LOCUS       DADQCX010000001        73906 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.001, whole genome shotgun sequence.
ACCESSION   DADQCX010000001 DADQCX010000000
VERSION     DADQCX010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 73906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.001"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(270..1766)
                     /gene="lysS"
                     /locus_tag="J8R83_000001"
     CDS             complement(270..1766)
                     /gene="lysS"
                     /locus_tag="J8R83_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAZ9573175.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="J8R83_000002"
     CDS             complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="J8R83_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAZ9573176.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="J8R83_000003"
     CDS             complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="J8R83_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAZ9573177.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3986..6097)
                     /gene="hflB"
                     /locus_tag="J8R83_000004"
     CDS             complement(3986..6097)
                     /gene="hflB"
                     /locus_tag="J8R83_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAZ9573178.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="J8R83_000005"
     CDS             complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="J8R83_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAZ9573179.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="J8R83_000006"
     CDS             complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="J8R83_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAZ9573180.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8297..8767)
                     /locus_tag="J8R83_000007"
     CDS             complement(8297..8767)
                     /locus_tag="J8R83_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAZ9573181.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8813..9238)
                     /locus_tag="J8R83_000008"
     CDS             complement(8813..9238)
                     /locus_tag="J8R83_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAZ9573182.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9305..9574)
                     /locus_tag="J8R83_000009"
     CDS             complement(9305..9574)
                     /locus_tag="J8R83_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAZ9573183.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9585..11180)
                     /locus_tag="J8R83_000010"
     CDS             complement(9585..11180)
                     /locus_tag="J8R83_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9573184.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="J8R83_000011"
     CDS             complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="J8R83_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAZ9573185.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14733..15293)
                     /locus_tag="J8R83_000012"
     CDS             complement(14733..15293)
                     /locus_tag="J8R83_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAZ9573186.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15646..16620
                     /locus_tag="J8R83_000013"
     CDS             15646..16620
                     /locus_tag="J8R83_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAZ9573187.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16790..18190
                     /locus_tag="J8R83_000014"
     CDS             16790..18190
                     /locus_tag="J8R83_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAZ9573188.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18268..18990)
                     /locus_tag="J8R83_000015"
     CDS             complement(18268..18990)
                     /locus_tag="J8R83_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9573189.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19069..19575)
                     /locus_tag="J8R83_000016"
     CDS             complement(19069..19575)
                     /locus_tag="J8R83_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAZ9573190.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19698..21497
                     /locus_tag="J8R83_000017"
     CDS             19698..21497
                     /locus_tag="J8R83_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAZ9573191.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21565..23139)
                     /locus_tag="J8R83_000018"
     CDS             complement(21565..23139)
                     /locus_tag="J8R83_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573192.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23394..23903)
                     /gene="mreD"
                     /locus_tag="J8R83_000019"
     CDS             complement(23394..23903)
                     /gene="mreD"
                     /locus_tag="J8R83_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAZ9573193.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23907..24761)
                     /gene="mreC"
                     /locus_tag="J8R83_000020"
     CDS             complement(23907..24761)
                     /gene="mreC"
                     /locus_tag="J8R83_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAZ9573194.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24916..25554)
                     /locus_tag="J8R83_000021"
     CDS             complement(24916..25554)
                     /locus_tag="J8R83_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAZ9573195.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25555..26205)
                     /locus_tag="J8R83_000022"
     CDS             complement(25555..26205)
                     /locus_tag="J8R83_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAZ9573196.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26218..27117)
                     /gene="rsgA"
                     /locus_tag="J8R83_000023"
     CDS             complement(26218..27117)
                     /gene="rsgA"
                     /locus_tag="J8R83_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAZ9573197.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27282..29351)
                     /gene="pknB"
                     /locus_tag="J8R83_000024"
     CDS             complement(27282..29351)
                     /gene="pknB"
                     /locus_tag="J8R83_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAZ9573198.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29348..30088)
                     /locus_tag="J8R83_000025"
     CDS             complement(29348..30088)
                     /locus_tag="J8R83_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAZ9573199.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30101..31459)
                     /gene="rsmB"
                     /locus_tag="J8R83_000026"
     CDS             complement(30101..31459)
                     /gene="rsmB"
                     /locus_tag="J8R83_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAZ9573200.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31459..32397)
                     /locus_tag="J8R83_000027"
     CDS             complement(31459..32397)
                     /locus_tag="J8R83_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAZ9573201.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32390..32881)
                     /gene="def"
                     /locus_tag="J8R83_000028"
     CDS             complement(32390..32881)
                     /gene="def"
                     /locus_tag="J8R83_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAZ9573202.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32896..35304)
                     /gene="priA"
                     /locus_tag="J8R83_000029"
     CDS             complement(32896..35304)
                     /gene="priA"
                     /locus_tag="J8R83_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAZ9573203.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35557..35862)
                     /locus_tag="J8R83_000030"
     CDS             complement(35557..35862)
                     /locus_tag="J8R83_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAZ9573204.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35867..36481)
                     /gene="gmk"
                     /locus_tag="J8R83_000031"
     CDS             complement(35867..36481)
                     /gene="gmk"
                     /locus_tag="J8R83_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAZ9573205.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36968..37252)
                     /locus_tag="J8R83_000032"
     CDS             complement(36968..37252)
                     /locus_tag="J8R83_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573206.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37270..38160)
                     /locus_tag="J8R83_000033"
     CDS             complement(37270..38160)
                     /locus_tag="J8R83_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAZ9573207.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38180..38398)
                     /locus_tag="J8R83_000034"
     CDS             complement(38180..38398)
                     /locus_tag="J8R83_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573208.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38368..40068)
                     /locus_tag="J8R83_000035"
     CDS             complement(38368..40068)
                     /locus_tag="J8R83_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAZ9573209.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGPYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40335..41108
                     /locus_tag="J8R83_000036"
     CDS             40335..41108
                     /locus_tag="J8R83_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573210.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41189..41758)
                     /gene="thiT"
                     /locus_tag="J8R83_000037"
     CDS             complement(41189..41758)
                     /gene="thiT"
                     /locus_tag="J8R83_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAZ9573211.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41824..41926)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41932..42903)
                     /locus_tag="J8R83_000038"
     CDS             complement(41932..42903)
                     /locus_tag="J8R83_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAZ9573212.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42997..44370)
                     /gene="glmU"
                     /locus_tag="J8R83_000039"
     CDS             complement(42997..44370)
                     /gene="glmU"
                     /locus_tag="J8R83_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAZ9573213.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44873..45691)
                     /gene="purR"
                     /locus_tag="J8R83_000040"
     CDS             complement(44873..45691)
                     /gene="purR"
                     /locus_tag="J8R83_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAZ9573214.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45858..46682)
                     /locus_tag="J8R83_000041"
     CDS             complement(45858..46682)
                     /locus_tag="J8R83_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAZ9573215.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46655..47335)
                     /locus_tag="J8R83_000042"
     CDS             complement(46655..47335)
                     /locus_tag="J8R83_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573216.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47358..48296)
                     /locus_tag="J8R83_000043"
     CDS             complement(47358..48296)
                     /locus_tag="J8R83_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAZ9573217.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48541..49392)
                     /locus_tag="J8R83_000044"
     CDS             complement(48541..49392)
                     /locus_tag="J8R83_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAZ9573218.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49546..52119)
                     /gene="mprF"
                     /locus_tag="J8R83_000045"
     CDS             complement(49546..52119)
                     /gene="mprF"
                     /locus_tag="J8R83_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAZ9573219.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52260..53066
                     /gene="proC"
                     /locus_tag="J8R83_000046"
     CDS             52260..53066
                     /gene="proC"
                     /locus_tag="J8R83_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAZ9573220.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53145..54701)
                     /gene="rny"
                     /locus_tag="J8R83_000047"
     CDS             complement(53145..54701)
                     /gene="rny"
                     /locus_tag="J8R83_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAZ9573221.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55112..56161)
                     /gene="recA"
                     /locus_tag="J8R83_000048"
     CDS             complement(55112..56161)
                     /gene="recA"
                     /locus_tag="J8R83_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAZ9573222.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFANPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56270..57511)
                     /locus_tag="J8R83_000049"
     CDS             complement(56270..57511)
                     /locus_tag="J8R83_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAZ9573223.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57751..58329)
                     /gene="pgsA"
                     /locus_tag="J8R83_000050"
     CDS             complement(57751..58329)
                     /gene="pgsA"
                     /locus_tag="J8R83_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAZ9573224.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58538..59422)
                     /locus_tag="J8R83_000051"
     CDS             complement(58538..59422)
                     /locus_tag="J8R83_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9573225.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(60200..61486)
                     /locus_tag="J8R83_000052"
     CDS             complement(60200..61486)
                     /locus_tag="J8R83_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAZ9573226.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61479..62747)
                     /locus_tag="J8R83_000053"
     CDS             complement(61479..62747)
                     /locus_tag="J8R83_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAZ9573227.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            62999..63460
                     /gene="mscL"
                     /locus_tag="J8R83_000054"
     CDS             62999..63460
                     /gene="mscL"
                     /locus_tag="J8R83_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAZ9573228.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63519..63965)
                     /locus_tag="J8R83_000055"
     CDS             complement(63519..63965)
                     /locus_tag="J8R83_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9573229.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64058..64303)
                     /locus_tag="J8R83_000056"
     CDS             complement(64058..64303)
                     /locus_tag="J8R83_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573230.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64418..64996)
                     /locus_tag="J8R83_000057"
     CDS             complement(64418..64996)
                     /locus_tag="J8R83_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9573231.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65073..65603)
                     /locus_tag="J8R83_000058"
     CDS             complement(65073..65603)
                     /locus_tag="J8R83_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAZ9573232.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65607..66467)
                     /gene="rlmB"
                     /locus_tag="J8R83_000059"
     CDS             complement(65607..66467)
                     /gene="rlmB"
                     /locus_tag="J8R83_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAZ9573233.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66460..66855)
                     /locus_tag="J8R83_000060"
     CDS             complement(66460..66855)
                     /locus_tag="J8R83_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAZ9573234.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(66852..68264)
                     /locus_tag="J8R83_000061"
     CDS             complement(66852..68264)
                     /locus_tag="J8R83_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAZ9573235.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68261..68797)
                     /gene="cysE"
                     /locus_tag="J8R83_000062"
     CDS             complement(68261..68797)
                     /gene="cysE"
                     /locus_tag="J8R83_000062"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAZ9573236.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(69119..70579)
                     /locus_tag="J8R83_000063"
     CDS             complement(69119..70579)
                     /locus_tag="J8R83_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAZ9573237.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70749..71906)
                     /locus_tag="J8R83_000064"
     CDS             complement(70749..71906)
                     /locus_tag="J8R83_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAZ9573238.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(71940..73310)
                     /gene="radA"
                     /locus_tag="J8R83_000065"
                     /pseudo
     CDS             complement(71940..73310)
                     /gene="radA"
                     /locus_tag="J8R83_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
     gene            complement(73373..73900)
                     /locus_tag="J8R83_000066"
     CDS             complement(73373..73900)
                     /locus_tag="J8R83_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAZ9573239.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT        20196 a        16105 c        13242 g        24363 t
ORIGIN      
        1 ttttgttatg tttttgaata aatattttct tctgtctttt ggacaagtaa taatatacca
       61 actaaattta gcttggtcaa cgaatttttt gtattttttc aagttttttt caataaacga
      121 ttattcataa cttttctttc tttatcgttc gttttcgtct tctttaatgt ctagaatagt
      181 cggcattagc ttttgaactt tcgttattat ttattccttt ctacacagca aaagctgcct
      241 aaggaattcc ttagacagct tttattcgat tatctcattg ttgggaatag caaaacatcc
      301 cgaattgatt gtgcatcagt tagcaacatt actaatctgt cgatcccgat gcctagacca
      361 ccagttggcg gcataccgta ttctaaggct tccaagaagt cttcgtctac accgtgagct
      421 tcgtcatttc ctagttcacg ttctttttct tgcgcttcga atctttctct ttgatcaatt
      481 ggatcgttca gttctgtaaa ggcattagca aattcgcgcc ccactatgaa tagttcgaat
      541 cgatctgtga atcgaggatc ttctggattt ttcttcgcta aaggcgaaac ttcgactgga
      601 tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa caaatgtttc aaagaattca
      661 ttgataacat gtccgacacc catagcttcg gttacttcta cattgtgttt ttcggctaaa
      721 gctaatgctt cttccaatgt catttcttgc cagaagtcta caccagtttg ttctttgatt
      781 gcatctacca tatggatgcg tttaaagtca ctttctaagt cgacagcttg tccatcatat
      841 gtgatttttg ctgttcctag tactttttca gctgcgttac ggataatacc ttctgtcaga
      901 ttcattacat cattgaaatc agtatatgct gtgtatgctt ctaacatcgt aaattctgga
      961 ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc cgatttcata aactttttcc
     1021 attccgccaa caattagtcg ttttaaatga agttctagcg caatacgcaa atataaatca
     1081 atgtccagtg cattatgatg cgtgataaat gggcgtgcgg cagctccacc tgcctcattg
     1141 tgcaatactg gtgtttctac ttcaatatag ccattgccat ctaaatagcg acggatttcg
     1201 ctgataattt ggcttcgttt cataaatcgg tcaaagcttt cgcgattact gattaaatcc
     1261 aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc catggtattt atctggcagt
     1321 ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt tgatagaaac ttcgcctgtg
     1381 tctgttttca tgatttgtcc agttacacca aagaaatctc caaggtctgc atgtttgaat
     1441 acttcatagg cctcatcacc tacttggtct tttcttacat aaatttgaat ttggccttca
     1501 cgatcttgta gatgcgcaaa tccagctttc ccttttcctc ggcgagtcat catacgacca
     1561 gctacactag cggtcaatcc catttctgct agttcttctt ttgttcttgg atcaaatagt
     1621 tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt ttccaaatgg atcgattcca
     1681 tcttcacgca attgttccat tttttgacga cgtacaagca tttgatcatt taaatcttct
     1741 acttgatgtt gttgttcctg tgtcacaaaa gttcctccat tctcatgtta atctctttcc
     1801 tataatgcca atgaaacaca aaaaaagcaa gccgaacttg gaatttcggc ttgaaaattc
     1861 acgaaaaact tagaaatcac aacgtttgtt tcaatagtac tttttccgct ttttctacaa
     1921 attgatccag caggtcattg atttcttgct gtttttctgt ctgattgatt gctactttca
     1981 ctttcgctgc tcgaggaatc ccttttaaat aataagccgc atgtgttctg aattctctac
     2041 aagctacttt ttctcctttg agatctgcta agcgttgtaa atgaagttta gctgtagcaa
     2101 ttttttcggc tggtgttggt tcaggaatca gttcccctgt ttcgagataa tgctgtgtgc
     2161 ggtgaatcat ccatggattg cccagcgctg cacgaccaat catcacaccg tctgcaccga
     2221 catagtcaag catccatttt gcatcttctg gcgttttgac atccccgttc cccataaatg
     2281 gaatcgtcaa atgttttttc acttctttca atacttccca gtccgctttt ccttcataca
     2341 tctgaacccg tgtacgtcca tgcatagcga tggcacttgc tccagctgat tgtgctgcta
     2401 atgcattttc tacagcaaag acgtgctctt catcccaacc aatacgcatc ttgattgtta
     2461 ctgggatatt tactgctgaa gaaacagctt ggaccatttc gtatactttc tcaggatcta
     2521 aaagccattt tgctcctgct tctgctttga ttactttatt tactggacag cccatattga
     2581 tatctattat atcggcagct gtgttttctt cgacaaattg agcagcttca actagactat
     2641 ctttatttcc gccaaatatc tgtaaactta atggatgttc tgtttcttca atgtggagca
     2701 tctctaaagt ttttttgttt ctgaaatgaa taccttggtc actgatcatt tcacatacga
     2761 ctaagcccgc accaaattct ttgacagtga ctcgaaatgc tgaatttgtt attccagcca
     2821 tcggtgcaac aacgacacga ttagggattt ccacattgcc aattttccat gtgtgttcca
     2881 cttaaatccc tcctaaggct tctttcttca atccatctaa ttcttcttcg ctatacttgt
     2941 atttgttatt acagaaagaa caaaccgctt ctgcaccgtg atcttcgtct atcattgctt
     3001 ggatttcttc tgcacctaac gcgataattg cttctgcaaa tttttctttt gaacagtcac
     3061 atttgaattg aacaggcatt ttttccaaaa tgttcaattc ttctgtacca agcaatcctt
     3121 tcaatatttc ttctggtgtc tgtccttcat ctaagagggt agagattctt ggtgtcgttt
     3181 ttaattgttc ttcgatcttg ctgattgttt cttcatcggc acctggcatg atttggatca
     3241 tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac caatacactc agtccaacag
     3301 ctgaagggat ttgttctgag atagcaagat agtaagtaaa atcttcagcg atttctccag
     3361 aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc taagtctttt gtgacagtaa
     3421 acattccttg tgttccaact gctccccgca catcgatttt accttcacta tttagaggaa
     3481 gactgagatg cggatttttg atgtaacctt tcacatctcc ctttccattt gcatctacta
     3541 caattcctgt tgctggacca tcgccttgga ttcgaacagt tagtttgtct tctcctttga
     3601 gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc caaagcagct gaggaggtgt
     3661 gccaagtatc atgacgtctt tgtgcctccg ctacggtatt tgttgcttga acggcgtatg
     3721 ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata atctttcatt tgttatgtac
     3781 tcctttttcc gtttttaaac tcatagtgaa tcatactagc aactactgct tttttcaact
     3841 ttggaatgct tcttttaaaa ataattcaga atcatctaga aaacaggaca tcaccctatt
     3901 tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg ttccggtttt cgggagtcat
     3961 atcagatcaa ttgacctata tttttttatt tgtattgatc gtctgaatga ttatcttctg
     4021 attgttgaga atctgaatca tgttctgctt tattttcctc attcagttca tgttttgctt
     4081 cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc tttttcttcc aaagcacgtt
     4141 ttgcttcttc aaaagttttc gcttcttttt cgcttggata atcatttgac tcagtacctt
     4201 caggcatcac accgtgttca aacaatgact tgattgcttt ggcatccaat gtttcgaatt
     4261 ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg agcttcgatg atttctcgag
     4321 ctttatcatg agcttccatc aagatttttc gtacttcttg atcaatctcg aaagcgactt
     4381 gttccgagta agcttttgtt tgaccatagt cgcggccaac aaacacttga tggtttcctt
     4441 catattgaac aggacctaaa cgatcactca ttccatattc tgttaccatg cttcgtgcta
     4501 gagctgtcgc ttgctcaaag tcattggaag caccagttga ttggacattg aagatgattt
     4561 cttcagctgt acgtccacca agtaagccta cgatttgttc aaacatatct tctttcgtca
     4621 tcaagaactg atcttctttt ggtaaagcga tcatatatcc gccggcgcgt ccgcgaggga
     4681 tgatcgttac tttgtggacg acccgagcgc gactcaatac taatccgaca atcgtatgac
     4741 cagcttcgtg ataagcaacc atttcgcgtt cttttttgct gattacgcga tcttttttag
     4801 ctggacctgc aatcacgcga tcttccgctt catcgatatc agaagcatcg attttctttt
     4861 tatttcttct agcagctact aacgctgctt cattcaagac attttctaaa tctgctccgg
     4921 caaaacctgg tgtctgttga gccacaactt tcaagtcaac gtcatctgcc atcggtttat
     4981 tccgtgcatg gactcgcaag attgcttcac gaccttttac atctggacgt ccaactaaaa
     5041 tctggcggtc aaaacggcct ggacgtagta acgctgggtc tagtacatca gaacggttgg
     5101 ttgcagcaat gacgattact ccttcatttc cgtcgaagcc atccatttct acaagcaatt
     5161 ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat accggcacca cgttgacgac
     5221 ctaccgcatc aatttcatca atgaaaatga tagctggtgc gtttttcttc gctgtttcaa
     5281 acaaatcacg aacacgactt gctccaacac cgacaaacat ttctacgaaa tcagaacccg
     5341 agatcgagta aaacggtact ccagcttctc cggcaacagc ttttgctaat aaggttttac
     5401 ctgttcctgg aggtccttct aaaagtacac ctgccgggat acgggcacct aattcaacaa
     5461 atcggcgagg atctttcaga aattcaacaa cttcaactag ttcttgtttt tcttcttccg
     5521 cacccgctac atcagaaaaa cgtacgcgat tagctttttt gtctgcttct ttggcttttg
     5581 atttaccaaa gttcatgaca cggccgccac cgccaccgcc gccgccttgt tgtcccatca
     5641 tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa gctaagcaat agggaaaccc
     5701 atataccgct gcttgattct tcttttactg ttgtagcaac tttgttttct tttgccagtt
     5761 ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat tgttgtgaaa tgggtagtag
     5821 tcgtatctgt tgaacctaag atagctaacc caccgctgtt agcgacggtc tgctgttctt
     5881 tgtattcacc agtgatctta tatacaccat ttgcaggctg cacttcaaat tctttgatct
     5941 tgcctgcttg tagttgttct gtgaattttg agtactcgat atctgacgat cgctggccgt
     6001 tattaccaaa aatgaaataa acgaccatta ccatcgctaa gattacgagg acataataca
     6061 aggcattttt catcatgccg ttgttctttt tgttcatagt tgccctccct aagcgtcaat
     6121 ttaatttaac agttttttat caatcctgac cattctattg taccataatt taattgagat
     6181 acagcattaa tttgattgat aaacactagg tttcaataca ccgatgtacg gaaggttacg
     6241 atatgcttct gcataatcca agccataacc gaccacaaat tcatttggta cgttgaagcc
     6301 aacataatct gcttcgatat ttactactct tccttcaggt ttgtcaagta gtgtaacaat
     6361 tttgactgat tttgctttgc ggtatttgaa aagatccact aaataagcaa gtgttcttcc
     6421 gctgtcaatg atatcttcaa cgatcaacag atcgcgacct tctacattcg tatctaagtc
     6481 tttgacgatt tttacttccc ctgacgagac tgttgcattc ccgtagcttg aaacatccat
     6541 gaaatccaat tccaaatacg tatcgataga acgaacgata tctgccatga atggtaccgc
     6601 tccttttaag acacctacta ctaggggatt ggtgttttgg taaatttctg ttaactcttt
     6661 gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag atcaaaattc tctcaatatc
     6721 cttttccaac atcaggttct ccttccaatt gcttcttttt gatatttgta aagaagtatg
     6781 tagtgtattt tatcagtttc ttcacgaata ctcaaatatg aaaaggcaaa aggtatcaag
     6841 ctatatatat ttcttttggc atctgtaatg atccaagcat gctgcctttg tgaattaggt
     6901 actttctgat cgataaaata tctagatact ttttttgtga gattctctgt taatttaatg
     6961 cggtctcctg cttttctttt ttcgacatac agttgcacat cagcaggaat ccaaatgtca
     7021 tgagaaaata gagaccatga atctgttgct ttgatgtccc ctgcattttc aggtttgacc
     7081 agaccaatcc attctgtttc attcaaatat attccttgtt ctggaatcag caacaagcgc
     7141 tggtcttctg tctggctagt tgcttgtttt tcttttttag agagtacaac aaaatgatac
     7201 tctcttttca gtatccaatt attgccaata ctgagttgcc attggctttt tttctgttgc
     7261 cactggtcta aaatcgactc catttgttgt tctttcaaaa taattcctgt ttttgagaat
     7321 gctttgtcga aaaaggagta aaaaaaatag tatcgttcag catctgtcat ttcttcaatc
     7381 atttctgcag aaaatcgaaa ttgttcctcc cactgttcga cttccttttc gatcaactgt
     7441 cccatatatt tttgaatgac ttggtctgcc cattggatct gttgcgaaaa ttgctggaaa
     7501 tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa ctaccaaatg acgaagccga
     7561 tttctctgga tatctaacaa ttggtttgtc tgatcctcaa agtaaacaag ctgcgattcc
     7621 gctgcataag tatataggtc ttctttgcta aaactcagca acggacgaat cagtctgccc
     7681 gtagcaaatg gttgtacttc tttgattcca gaaaaagtat ttaactgtcc cccacgaacg
     7741 attttcatta acaccgtctc gatttgatca tctccgtgat gagcagtcat caacgtgtca
     7801 tattgtcctt cttccatcac gcgagtgaat tcttgataac gaaagttacg agcttctgtt
     7861 tctatggcgg atttggctgg atcttcccaa atacttacat ataaagggag attcttctct
     7921 tcacaatatg agcgaagata ggcagcttct tctgctgatt cttctcttaa ttggtgattg
     7981 atgtggacga tacctaaaga aaaaccgatt tggcgttgca cttgtaaaag taaatggagc
     8041 aaaaccatcg aatcaacacc acctgatacc gctgctaaaa ttctcgatcc ttgttgccag
     8101 aatccttgtt cattcccgtg ccgaataaat gactgctgta atagcggtgc ttttttcccg
     8161 cctttttcaa cgttcatcct ttccacaccc tttcttccta aaaaaaagag agcgggaaaa
     8221 cgtctaaaac gacaattaac ctgccctctg ttgatactat gacccaaata gtcgcactat
     8281 cattatttgc ggctttttag ctgcgacgtc cgccacggcc accgcgcttt ccttctgtgt
     8341 ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa aaatgaactc atcaatgaat
     8401 cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa agattttttc tgtgctggac
     8461 gatttcggtt gtcacgggga tctttttgtt gatatttttt aggacggctt tcttctccag
     8521 attcagcagg ttgttcctgc gctttccgga tagatagtcc gatttttcca tcatcattta
     8581 ctgaaataac tttaactgtt acttcatctc ctacacttaa aacatcatgg atgtctttta
     8641 catagccatt tgacacttcg ctaatatgaa ctagacccgt ttttccagca cctagatcaa
     8701 taaacgcacc aaaatttgtg attcctgata cttttccttg cagttttgct cctacctcga
     8761 ttgacataaa aaaaatgttc ctcctaatta tttccctttt ttatattcct gcttattttg
     8821 cagttgtaga actagttgat tgatctgttt catttgtcga gctgtctgta tttgattcta
     8881 atataggata aactttttca ccgtcttttg agtaaaagaa tttgcttctg gcaagtttag
     8941 ctacatactc atcatctttc agcaatgaaa catcttggtg cagctgatca acgtctgcgt
     9001 tgacttcttt catttcagta tttgcttcga ctctcaattc gttcaattga tgcatccttt
     9061 gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat gaccaaagca ccaacaaaaa
     9121 ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg ttgttgctga aattcagcat
     9181 actttttctt tgcatattcc gtatctagcg cagcgatttt attgcttttt ttcgtcactt
     9241 ggattcgctc caatcttttt gattgtcttt ttcattatac caatatcgtg aaagcttgtc
     9301 taatctattt ctctagtgtt tctgtgcgat tttcagaaat aatttcgtac attttttgtg
     9361 catcttcttt tttggttgat tcatgtaatt ccgtaatttt cacttccaac gttttgttgc
     9421 caaactggac tttcaaaata tcgcctactt tgacatcact ggaagatttc gccaatttac
     9481 cgttgatttg aattcttcct ttatcagcta cttcttttgc tactgatcgt cttttgatga
     9541 ttcgggaaat ttttaaaaat ttatctaatc gcatatctta ttcctcactt tttaattttt
     9601 ttatttaatc gcaggatttt cttaccaaaa ggcaacatta gccattctcg tactgtaaac
     9661 agacgaagac gaatcactgc ataaatgaac acagaagccc cgatcccaac tcctatcacg
     9721 ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa atactatatt caatacacca
     9781 taatacagca gcagtactac tgtcatacaa agaaggctga acatcaactt ccgtccaaaa
     9841 tgccgttctt tccaaaaagc atttagctct tttgtttcaa ttcgaacaaa ataccaaagc
     9901 gtcacaccta atcctaaaag ggtagacagg cttgcacctg ctgttcctaa taaaccggtc
     9961 agaaaagaag tagtcaatcc ttttaccaat agtccccatc ctgcgccttt taaagaaggg
    10021 cgaaacgagt tcttgctttg agcaatactt tgataagctt ggatgactgc agtgaaagca
    10081 atggaaaaaa caaataatac aagcgctgca tttcccgcat aatctttaaa caacgcataa
    10141 ttgatataag ggagcagcaa ggctaatccc aaagacgcag ctaatgctaa agcggtcgtc
    10201 aatctaagat agattttggc tgtctgtaaa aactgacgat agatccggtt ggtcaaatga
    10261 cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg caatcactaa acctaattgt
    10321 actaaaggct gacctcgatc atagacccct tttgctatct tcgcaccgta ttctgacagt
    10381 ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga tcagctggaa aaagataagc
    10441 aatccactat aaatcgaaac cagtccgcct tctaccagaa aacgccggat caagggcttt
    10501 gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg ctcctccatg aatcttttgt
    10561 tcatagtagt gaaggatccc atatgcgcat aaaccgccaa aaacagctcc actcattgct
    10621 gccgtccctg tttggtacac cgtccatcca agctttctaa aagcaaacgc actacagaca
    10681 atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa cagcagttgg ttccatcaag
    10741 aatcttcctt ggaaattccc tcgataaaaa gatagaccag gcatcagcaa aaaggtaaag
    10801 gaaactactt ggatcagcgg tttcaattgt atgtctccca tcatccaagc aatccagctg
    10861 ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc aaaatactaa gggataaaga
    10921 ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt ctgcaacgta ctttgatatg
    10981 aactgcggaa gaccggataa agctaaagtc attgctatcc cataaattgg ataaacttgc
    11041 tgataaacat aaaaaccttc gtcgccgact aagttttgga ggggaattcg gtaaagggca
    11101 cttaatactt ttgctatgaa agaagcaatc gtcaatacaa atgctccttg catgacgcgc
    11161 cgcatttctt tatgatccaa atcattgctc cttcctacgc tgacagatat ttttgctcac
    11221 gcaacgcttt gacaaacttt tggatttcct gaagccatac tgcttcttcc atttggttgg
    11281 ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc tagactggct tttagttttg
    11341 tcgctgtcag tgcttcgaat aactgttcca cactatagcg ttttgttcca actttactta
    11401 gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc taggagcgct cgatcgccat
    11461 ccattttgat ctgcccaatt gtcaagagat gtgctacttc ttctggatat tctccaaaac
    11521 ggtcgagcag atcatcttct agttcatcta gcatttcttg cgaatcaagt tcacgaattc
    11581 gtttatagat ctcgattttc tgccgttgat ctgccacgta tgtttcaggt agatacgcat
    11641 cgacaccgag gtcgatctca acagtggtct tctccacttg actattcttt ccttgtttac
    11701 gagaaacagc ttcgcttagc atttgagaat acatatcgaa accgactgca tcaataaatc
    11761 catgctgctg agcacctaag agattacctg caccgcgaat ggaaagatcc cgcatcgcaa
    11821 tcttgaatcc agatcccagt tctgtaaaat ctttgattgc ctgaagacgt ttttcactga
    11881 cttcgttaag gatcttctgc tgctcataca taaagtaagc atatgcgaca cggctgcttc
    11941 ttcctacccg ccctcgcaat tggtataacg tggataatcc catataatca gcgttctcaa
    12001 cgaacaacgt atttgcgttc gggatatcta ctcctgtttc aatgatggtt gtagtgacaa
    12061 gaacatcata ttgaccttca ataaattcaa aaagcgtatt ttctaattgc gcctctgtca
    12121 tttgcccatg agcataaccg atccgtgctt ccggaacgag ttcttggatt tcttctactt
    12181 tttgttcgat cgtttctacc cgattatata aatagaatac ttgtccacct cgtcccattt
    12241 ctcgatggat tgcttcgcga atagctccag gatttttttc cataacatac gtttggatcg
    12301 gataacgatt cgcaggcggt gtttcgatta ctgaaagatc ccgcacgcct aacatcgaca
    12361 tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa aacatccact tgtgcacgta
    12421 actgtttcaa tcgttcctta tgttttacac caaaacgttg ttcttcgtca atgatcagta
    12481 gacccaaatc gctaaattca atatcttttg acaaaattcg gtgggttcct acaacaatat
    12541 caacttgacc tgtacgcagt tgttcgatgg tttctttttg ttgctttctt gttctgaaac
    12601 gacttaatag cccgatattt acggggaaac cttcaaatct ttccagcatc gtttcatagt
    12661 gctgctgtgc caagatcgtt gttggaacta aaaaggctac ttgtttgctt tcctttatcg
    12721 ctttaaaggc cgctcgaagc gctacttctg ttttcccata accaacatca cctacgagta
    12781 gtcgatccat tggtttttct ttttccatat cccgtttgat ctccgctgca cttctcaact
    12841 ggtcatcagt ttcagagtag gggaaggcat tttcgaattc tttttggtag gcgtcatcag
    12901 gtccaaaagc atatcctttt tctgactctc ttgcggcata taatttgatt agatcgtcag
    12961 cgatatcctc gatttttgaa gagacttttc gcttggtttt cgtccattca cttccgccta
    13021 gcttattgat gcgaggcgct ttggcttcag aggcgacata tttttggatc agattcagtt
    13081 gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa aatagtcata tagtcttggt
    13141 gaacgccatc tacttctagc gtttccatcc caatgtattt cccgatacca tgattggcat
    13201 ggacaacgta atctcctgct tttaactcat tatagctttt caatcgctct gcgtttgtta
    13261 ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa aatttctttt tctgtgatag
    13321 ctactatttt ttcttgagga agttcaaaac cagcctgcaa agctccttca actaattgta
    13381 cctgtcctct gatcaatgca tttttttctg tttctactac taatatgtct tcatctcgaa
    13441 gcatttgttc tgctttgcgt attctgtcct ttgtcggaat aaagatcaca acagtctgtt
    13501 tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg catttgtccg aagaactgtt
    13561 gcatcgtccg atattgaaaa ttatggattg cttggaaacg aagatttccc atcccttttt
    13621 ggaagagtga gaaaaaggtt gtggtgaact tttccttctg cacgattttt tgtatatctg
    13681 ctgaaaatgt ctgctcagaa aacacccgca attcgctgat tttttgagtc tgccattctg
    13741 ccgcttccct ttcgatttcc cgatttgttt ccatgattcg ctgataatca tcaacgacta
    13801 gtaaactatt tgaagggaaa taatccaaga tcgtcacaga ttcttggtaa agaagatctg
    13861 agtagaattt tgcttcttct gtcgggacac ctgcttgcca gcttgaagtc agctgaccga
    13921 agtaatcttg caaaaactcg cggtctgctt cttctgtggt cgcagcaagc cgtttttcta
    13981 gcattttttg catttgctct attccatgtt ctagatcctc tggtccgtag acttgttcac
    14041 tcgttgggga aacccagatt tcttccgttt tttcgattga gcgttgtgtt tctgcttcaa
    14101 aataccgcat agaatctatc tctacatcaa atagttctac acgaacagga taggttgtcg
    14161 ttaacgggta aatatcgata atgcttcctc gaatactgaa ttctcccggt tttgcgacca
    14221 tctcttctcg tacatagccc atcaaagtca attggcgagg aagattttcc acgtctatct
    14281 catcaccaat atgccaattc aattgcgcct gtagccaagt tttcttattc ggcagtcgtt
    14341 tgtgcaaaga tgcgactggc aacaaataga tacctgcttt tttttcttga agtgcgttaa
    14401 gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa ggccatttca gcagaaagca
    14461 cttcatccac tggaaataaa tggatctgat cttgcggaat cacatgttgc agatcttctg
    14521 ctaactgatt cgcataatac aaatttggca tcagaataat catgttttta tttgttttct
    14581 taaacgctcg agcaaataga agtgttttcg ctgagcccgc taatcctgtg attagttgtc
    14641 taggcatttt ttcttctaaa ttgctgaccc attcttttac ttgcggatct tttccgacta
    14701 attgaataat atccattcct tttcctcctt cctcaattga atcgattcat cgcatccacg
    14761 aacgaatgcc cttctatgag atattcgact gctttaacag attgacacat gctttcttct
    14821 atcaaaggct gattttcttt gctgaaagga ctaagcacat gctggactac tgtttttttc
    14881 ccttctggcc tgccgattcc caccttgatt cgatcaaaga cattcgtatt caaatgggaa
    14941 ataatacttt tgataccgtt atgcccgccg gcacttccct tttgacggag ccggattttt
    15001 cccactgcca gatccaaatc atcgtagatt acgactaatt cctctggata aatcccaaaa
    15061 taagtcatta gtgggccgac tgcacgacca gattcattca tgaatgtttg tggtttgact
    15121 aaaaggatct tttctccatt atgaaaaaat tcggcaactt ctgcttcgaa cggatttttt
    15181 ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga ccataaagcc gatattgtgt
    15241 tttgtatatt ggtatttggt acctgggttt cctaacccga cgatcatttt catttttgtt
    15301 ttccacctaa ttctaaaaag cagcacaaaa ggctggactg ctaattagcg gtccagtcca
    15361 tcgagctttt ttctttttta cacttgtcaa tgcatagtat aacacaaaac aaggcgtttc
    15421 ggctaaaaga gaatcgttaa taaatgataa agaaattaaa aatttcttca aagtttaatg
    15481 aaataattga tatataaaaa tagtgaaata acgcacatgt aagcttttac atataataca
    15541 accttgttat ctgttatatt ttatagccaa atagcgtgac atggggcttg agaaatgtta
    15601 gcataagcat gggaaaaaac aaatcaatgg aaggattgat actaaatgac tgcagctgca
    15661 gaaaaaaaag atcatcaaaa agttattctt gttggagacg gcgccgtagg ttctagctat
    15721 gcctttgctc tagttactca aaatatcgct caagaagtag gtattgtgga tatcaatact
    15781 gctaaaactg aaggagacgc aattgacttg tctcacgctt tggcatttac ttcacctaaa
    15841 aaaatctatt ctgctactta cgcagacgca catgatgctg acttagttgt tattacagct
    15901 ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag taaacaaaaa cctaaaaatc
    15961 aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta acggtatctt tttagttgcc
    16021 gctaacccag tagatatttt gacttactca acttggaaat tctcaggttt ccctaaagaa
    16081 cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt tccgtcaagc acttgcggaa
    16141 ttagttgacg ttgatgcacg taacgtccat gcttacatct taggtgaaca cggagattca
    16201 gaattcccag tttggtcaca tgcaaatgtt gccggcttgc aaatctatga atgggtaaaa
    16261 aacaacccag aaatcgatga agaagctatg gttaacctat tctttggcgt acgtgacgct
    16321 gcttacacaa ttatcgagaa aaaaggcgct actttctatg gtatcgcagt agcattagca
    16381 cgtatcactc gtgccatctt agatgatgaa aatgctgttc ttcctttatc agtattcatg
    16441 aatggcgaat atggattgaa cgacatctac attggtgcac ctgctgttat caaccgtcaa
    16501 ggtatccaaa aagtaatcga aattccttta agtgacagcg agcaagaccg tatggctgct
    16561 tctgctaagc aattaaaaga aattctagat gaagcttttg ctaaactaga cgctgaataa
    16621 tctttgaaca tgacggaaaa catctattcg gtgttttccg tttttttatt ttatcaccct
    16681 tatggtttct aaattttttc ataaagtaga gataaccttc gtcttttcct ctaaattatg
    16741 ctatcatgag accgttccac cctaaacttt tacttaagga gttgtcgata tgacaagatc
    16801 ttcgcatcga aaaaaatcga aacatgttgc tttgctttca gttcttggtg ttctcttagt
    16861 gctgatcagc ttttatacct atcgcagtac atactacaca aagcattttt tgccgaatac
    16921 agaaataaat ggaataaatg tcagcaatct aacagtcgaa aaagcaaatg aaaaattaaa
    16981 agaagcttat tctgataaaa aactggctat taaagaagat ggaaaagtct ggcaggaagt
    17041 accaaaatcc gagctcggct acaaagatga tttcacttcg gagctttctc cgatcctaaa
    17101 tgaacaaaac ggatggactt ggggaatgac ttatgtctca gcggcagaaa aacaagaaat
    17161 agatcctgtc agtcaaaacc accaaaaact agacactacc gttcagacat tgacaactaa
    17221 gctgactgat ttgaacaaag accggacacc tactactgat gcaacgatcg aaaaagcagg
    17281 tgactctttc gttatcaagc ctgaagtcaa tggaaatacg atcgacgtcg atgctgcggt
    17341 caaacaatta aaaagtgcgg taaactctgg taaagataca attgaattga ctgaattcaa
    17401 agaaaaacca aaagtaacat ctgaagacag ctcactgaaa gaacaactcg catccatgaa
    17461 tgctatcgca aatgtaaaag ctacttacag tataaacggt gagactttcc agatcccatc
    17521 aagtgatatt atgagttggc tgacctacaa tgatggaaaa gtcgatttag atacagaaca
    17581 agtacgtcaa tatgtaacag atttaggcac aaagtataac acaagtacga atgacacaaa
    17641 atttaaaagt acaaaaagag gagaagttac ggtcccagtt ggcacttaca gttggacgat
    17701 ccaaacagac agtgagacag aagcattgaa aaaagcgatt ctggcaggcc aagattttac
    17761 tcgttcaccc attgtgcaag gtggcacaac cgctgatcat ccattgatcg aagatacgta
    17821 tatcgaagtt gatctggaga accagcatat gtggtattac aaagacggaa aagtggccct
    17881 tgaaacagat atcgtttccg gaaagccaac tacacctaca cctgctggag tcttctatgt
    17941 ttggaataaa gaagaagatg caactttaaa aggaacaaat gacgatggaa caccttacga
    18001 gagtccggta aactactgga tgccgattga ctggacaggt gttggtatcc acgattcaga
    18061 ctggcaacct gaatacggtg gagacttatg gaaaacccgc ggttcacacg gctgcatcaa
    18121 caccccacca agtgtaatga aggaattatt cgggatggtc gaaaaaggaa cgcctgtatt
    18181 ggtcttctaa caaaaataat atataaaaag aaagcacccg tacgattggt acaggtgctt
    18241 tctttttatt atctaacaat gtgctactta catttcagca gcagtaaaga cttctgaaac
    18301 atcatcatcg tcttctagct tatctactag acgttccaat tgctcttttt gttcctcatt
    18361 taaatcaatc gtcgtttgtg gaatcatcgt caattctgct tgcgccaaag tgaactcttt
    18421 ttccaactca tctcgtacag cagcaaaatc ttctggtgca gtataaatct cgaatacttc
    18481 aggagaagtt tgcagatctt ctgcccccgc ctctaataca tcctcaaaca tcgtctcttc
    18541 atcaacagtc aacccatcgc gttcaatagc gatatatcct ttgcggtcaa acaagtaact
    18601 gactgaaccc gtttctccca gtgatccacc gtttcgagta aaagctactc ggacatttgt
    18661 cgctgtccga ttacggttat ctgtcaatgc atggactaag attcctactc cacccggacc
    18721 atatccttca tacgtgattt catcgtaatt cgtttcatct acggcactcg tagccttttt
    18781 aatcgcccgt tccacattgt cgttaggcat atttgcagct tttgctttgt ccacaacaag
    18841 ccgcaaagct ggattcatag atggatcagg accgcctgct ttagctgcca tataaatttc
    18901 acgagaaagt ttctgaaaga ctttccctcg ttttgcatct tgggcatttt ttcttccttg
    18961 gatattatgc catttactat gtcctgacat gatttttcct cccttgttct tttgagaata
    19021 cacttctatt ctagtactat ttcacaaaaa aacaaagcca cagccaatct ataaacgctt
    19081 cttgaatgcc gcaaaaagca cacataatat cacagcagtc agagcaccga tcgaatccaa
    19141 catgacatct tggaacatag gtgttcgtcc accggtcatc atctgatgga attcgtccaa
    19201 acctgcgtac cctgttgctg aaagccaagc aaggatcgct gtcagccacc aaatttttag
    19261 cttggggaaa acacctaaaa acaagctgcc tcccaaaata aaataggtac cgaaatgtgc
    19321 gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc agatggttga tactcaccat
    19381 acttccacca taattaaaac gtatacccgc taatgtgtct ttaaatggct gattaggcag
    19441 ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa gtttgagaag aactgtaaaa
    19501 taagattata acgactatca gtgcgattac taaataaata tttccgtttt tcatttgttt
    19561 ttttgaagaa ttcataagtc acctctgtat tttatcttag actttttttg aagaaacaac
    19621 aatcattttc atagagactt cttccataaa aaagtgctat acttaatttt gtattacaat
    19681 atgaagggag ttttttcatg agttattcat taaattggaa tctagattct attttttccg
    19741 gaggcagtca ttctgatgct ttgaaccaac ggatgaagca attggaagac caaatgaacg
    19801 agtattatca ccgcgtaaca aaatggtcac ctagttctga caatgcagag cagttaaacg
    19861 ctattcttca attgcaagaa acgattacga atggttttac ccaatgcagc agctatatta
    19921 ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa ggtcttatca ggcaagcttt
    19981 acgcaatgct gcctcgtctg caatcagccg aaactgtatt gtcaaagaaa tttgcagaaa
    20041 tatctgacaa tgattggaat cagatgcttt ctcaatcttc gtttgaaaca attgcttttc
    20101 gtttaaacga gattcgtcgt gatggctcac aattattatc agaagctgaa gaaaacatta
    20161 taaatacgct ttctttagat ggtctaaatg cttggagcag tcattatgat acgattgtag
    20221 ccagcatttc gattcccttc gaacaagatg gacaagtagt cgaattatct gctggacaag
    20281 ccttcaataa gatgatgggc gatccagatc caaaagtcag agaaacactt ttcgcagcat
    20341 gggaagaagc ctggaaagaa aaggcacccc tcttcacgga tactttgaat catttagatg
    20401 gttttagact ttctgactat gaacttcatg gtgtcacaga ttttctacaa aaaccattag
    20461 agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg ggatacaatc cagaaaaaca
    20521 aacaacccct tgttaattac ttgactagaa aagctaatct tttcggtaaa gaaaaaatgg
    20581 aatggcaaga tcaagatgca cctattattt taggcgattt gaaagaaaaa acctttagtt
    20641 ttgacgaagc agcagcattt attatcgaaa actttaacaa attcagtcca aaaatggcta
    20701 aatttgccca atctgctttt gaaaagagct ggatcgaagc agaagatcgt cctgggaaac
    20761 gtcctggtgg ttattgtact gagttaccag aaacaaaaga atcaaggatc tttatgacct
    20821 acagtaattc tgttaatgag gttgcgacac ttgctcatga actaggacat gctttccata
    20881 gcagcacgat gtgggattta ccttctttaa atcgcgaata tgccatgaat gtcgcagaaa
    20941 cagcaagtac attcgcagaa ctgatcgtag ccgatgctac attaaaagtc gcaaaaacaa
    21001 aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa tgctttagct atgttcatga
    21061 atatccattc ccgattcatt tttgaaaatc gattctatga agcacggcaa gaaggattag
    21121 tctcagaaga taagatcaca gagatgatgg ttgaggcgca aaaagaaggc tatcaaggag
    21181 ctttagctac ttaccatcca tatttctggg ctgcaaaatt gcatttcttt attgatgacg
    21241 taccgtttta taacttccca tacacatttg gctacctctt tagtttgggc atctatgctt
    21301 acgccaacca aaagggagca aattttgaag aagaatatat ccatttacta cgcgatactg
    21361 cctcaatgac gacggaagat cttgcgaaga aacatttgaa tgtcgatctt acccaaccag
    21421 atttttggca agcaggtatc gacatggtga ctgaagatat ccaaacgttc atggaattga
    21481 cagaagaatt tatctgattt ctattttatc acaataaaaa aagagttagt ccagaatggg
    21541 ctaactcttt ttgattaatc attcttacat gctgacagca aagtcagggg caaaccattg
    21601 aactgaacca acttttacgc tttcgcctgg ttgaggagca tggatatatt gtcctccgcc
    21661 taaagcaatc gctacgtggt aagttccgcc ttgtgacccc cagaataaca agtctccagc
    21721 ttttgcttga gaaactgaaa tttttgttcc agctgattct tgaggaactg tccaaccacc
    21781 gatgtcacga ccagttactt gcatgtaaac atagcgtgtg aaccctgagc agtcaaagcc
    21841 acttggatct ttaccgcccc aaacatatgg agtaccaata tatttgtaag cttctgctac
    21901 gattgctgca ccattcacac ttccagaagg agctggagca ggtgttacag gttttggttg
    21961 ttcaggtgtt ggtgttggcg ttggagccgg agtactactt cctgtgccgt ttcctgtatc
    22021 aacactttga tctgttgatg gtgttgtagg cgcaggtgtt gttgattctt ctgttgttga
    22081 agattcaggc actgttgttg attcttctgt tgctgaagat tcaggcactg ttgttgattc
    22141 ttctgttgct gaagattcag gcgctgttgt tgattcttct gttgctgaag attcaggcgc
    22201 tgttgattct tctgttgaag attcaggtgt tgttgattct tctgttgctg aagattgtgt
    22261 agctgatgat gattcttcag tcattgaaga ttgtgtagct gatgattctt ctgttgctga
    22321 gctttgtgca gtagatgaag cttgagtagc ttgtgcttca gcctctgctt gttcgcgtgc
    22381 ttctttttca gctttttctt gtgcagcttg ttgacgagct tgttctgcta gacgttgttg
    22441 ttcacgaata cgagcttgct ctgcttcagc ttctgctttt tgacggttca agtcagcttt
    22501 cttgtcttca gcagttgctt gttcagcagc taatgaagtt ttcagtacgt tcaaatcagc
    22561 ttgtttagat aaaagatcgc ctttttgaga ttccaaagca gcttggtttt cagctaattc
    22621 ttttagttta gcatcgtttt cagctttttt gtcttctaca gcttttttat cttgtttttg
    22681 ttgttccatc aagtcgttgt ttgcttttac catcgttgtc attgcttgaa cgcgtccaat
    22741 agcatctgct aatgaatcag cattcaatac agcatcgatg tagtttgagc ttgtgttgct
    22801 tacttgtgct tcgcgtgctt gtttttggat tgtatcttca cgtttttcaa tacgttcttg
    22861 taaatctgca atgtctttta ctaattgtgc agattcttga cgcaatgtat cttgttttgc
    22921 taataggtct tgtgcttgtg tgttgatttc agaaacttgg ctttctaagg catcgatttg
    22981 tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc ttttgatctt gctgttgtat
    23041 ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat gctacggcag tcaaggtcat
    23101 tgaacatacc attactgctg atattaaact ctttttcact cttcattcct ccgactggct
    23161 taatttaata aatatctaaa tatatttaag tctttcttaa cgatataaaa attgtaccat
    23221 agcagtgtgt caacgatata atagttatgt tacaaaaatg tttcaaaaca acttttaaaa
    23281 atgacaaaac tgttcgtttc agaaaatgat catgaaaaag ccgcgttaag tctagcattt
    23341 cttaagataa caacgattct ttttcgcttt cgacctaaaa ataaaaaaag aaattattca
    23401 tcactgaata atttcttaaa gggaaaaatg aataatacaa atataatcat gttcaacagc
    23461 agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat ttactactgc taatttaaaa
    23521 atcaactgga ccaccatcgt aaacaattca taacccgtga caaagatgat catactgaaa
    23581 aattcagtaa agatgttgac atggataacg tctttcatta catacatcaa ccatacaatt
    23641 aaagggagag ctactgcata gataccgata acgccaatat agtaagcgtc atagatagcc
    23701 ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa acgccatact gcaacataat
    23761 aatgccaata tcagaaagtg ggcatttgac atataggtgc ctttcgacca ctcccctagc
    23821 attcttgtta aatgaccatc tatcaacatc aaaaagaaca aaacgattgg cagatagtac
    23881 ttcattgttt ctttcttcaa catggactaa tcctccgcta gccgttggac aatcgtcaca
    23941 actgacacgt catacatttc tgcataaggt ttcacataaa cttcccgatc cagcccataa
    24001 ctatctggtt tcgttttaat aaccgtaccg atcggcaagt tagctggaga attccctcca
    24061 agaccggatg tctggacaac atccccttct ttgatatccg tatcaccagt taattgggtc
    24121 accactaagg catggagctt ttcatcatag tttttaagca aaccaaacgc ttcgccatta
    24181 gccgaagata cccgtactgg aaaatgattg gagctttcat tagaggatga cagtaattcg
    24241 attttagacg aagccgtatt gacctcgatc actcggccaa tcaatccttt ttgcgacatg
    24301 actgccatat ttgcttcgat accgtcttta gaacccttgt ctacgatcag catgtcctgc
    24361 caactgtcag gcgaacgagt aatgacattt gccgttactt tttcgtaact agtcagcgtc
    24421 tgattcaact caagttcttt tttcaacgct tcgatttctc tctcgtaatt cttgttttgc
    24481 tgtgaaacgt catcatagct atcgattttt tcttttagcc gctcattttc ggcataagtt
    24541 gaaaaaagat tatggacaga atctactcca tttcgtaccc accgtactgg ggcagagatt
    24601 gttttatcaa ccattgcaac actgtcatta acgatggatt ggaagaaatt gggctttcct
    24661 tcattcgctc gctgcgcagc ggtcacactt agtatcgtca ccacgatgat aacaataacc
    24721 aaggtaataa taatattttt attaggattg aacttcttca caaagacacc tcgaattaat
    24781 tagactcttg tgttcaattt tatcactaaa tgccgtgaaa caaaaggtaa gttgctcctc
    24841 ttaagctttt ttttagcaaa taatagattc tgtcattttt agcctgaaag acaaattttt
    24901 ttatttgttt atggatcaat ctttgctttg aataactgca atcataccat ctgaaaaaga
    24961 aaattctgcg gtatctgaaa gaaattcgtt acttgcataa gatgtcggat attctacttc
    25021 tttattttcc aatacatact tgctgccttt taatgtaaga ttcgagacgg gagtcaagca
    25081 gcaataagct aaatacttca tatctggtat ctgtcttact atatgctctc caggcaaata
    25141 ataagacaaa taattttgac aatctctgat aataagctga tgggcaaagg gtttgaagcg
    25201 aggttccata cctaaccaga gattggctaa aagatgatcc aatcttccgc ccgtagctcc
    25261 aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt tttaagatac ctaactgtgt
    25321 atctgtatcg tctttttctg caggggaacg ggtatactct ttggcttttg caaatacttc
    25381 cttctgctct tcgttcgaca atgaatcaaa atcacccact gccagatcta ctgggtagcc
    25441 tgcttgaagc aggtacagcg caccacggtc tatcccgaca taggcatcgt atttggacag
    25501 cagagactgc ggccagtttt gcggattacc tccagcagct aataaaattt tcatttagtc
    25561 taatgcctct tttaatcgtt cgatttgtcc gactggattt tcggctccat agatatatga
    25621 tcctgcaacg aagacatccg cccctgcatc tttacagatt tttgctgttt ctggaacgat
    25681 tccgccatct acttcgattg cataagtcca attgttctct ctacgtagat cagcgagttc
    25741 cgtaattttt tctactgttt cttcaataaa gctttgtccg ccgaacccag gattgacagt
    25801 catgactagt acttgatcag ccaaaggcaa aacatgtttg atcatggaga ctggtgttcc
    25861 tggattgata actactccag ctttaactcc taagcttttt gtcatttgaa gtgcccgatg
    25921 aatatgagga gttgcttcga cgtggacagt aatgatatct gctccagctt ttgcaaatgc
    25981 tggaatgtag ttttctggat caacgatcat cagatggacg tctaacggta atttagtaac
    26041 aggacggatt gcctgaacaa tatttggccc taatgtgata tttgggacaa atcggccatc
    26101 cattacatct acgtggatgt aatctgcgcc tcctttttcc actaactcaa tgtctctttg
    26161 taaattggca aaatctgcac tcaaaatgga tggtgctatc ttcattcttg tttcctccta
    26221 ttttcgttta ccttcttttt ttgcatacat tggttttctt ttttcgattt cttgtaagaa
    26281 ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct gtttctactc tatgttttac
    26341 ttcgcagcca ggttctttag catgcatgca ctctctaaat ttgcaatgga cagaagcttc
    26401 tacaaattca ggaaattgtc tcggcagttc tcctgcttca attgtcaaaa agtcaatcga
    26461 gctaaatcct ggtgtatctg ctactaaccc gccatagata ggaatcagtt ccacatgacg
    26521 tgttgtatgc cgtcctcttc caagtgcatc agaaatctct cctgttgcta aattcagttc
    26581 cggtgatatt tgattcagta gcgtcgattt tcctgctcca gactgaccca taaagaccga
    26641 tagccgttct gggaagtaac ggatcagttc tgtcgtatca cccgtatgat tgggtacaat
    26701 caccggatag cctattttag tataggtttg cttgatctct tcgatttttt ctgggtcgtc
    26761 tgacaagtcg gtctttgtca aaaaaataat cggttcgatc gactcgtatt ccaaggtaac
    26821 tagaaagcgg tcaagtagat tataagaaaa tgcaggctct acgatacttg tgacaatgat
    26881 tccaagatca acatttgtga ctggtgggcg aactaattga ttttttctcg gcaagatttc
    26941 cagaagatag ccgtctgttt gattttcact ctcaaagatc acctgatctc cgacaagcgg
    27001 cgtgattttc cgattccgga aatttcctct tcctcttgtt tgataggtct ctccgtttgc
    27061 gtatacatag taaaaaccgc tgattgcttt tctgatttgt cctttgataa gtgccacctc
    27121 cgtttttgtt tattttacca tacgaagagg aaagtaggtg ttattccatg caaacttctc
    27181 aaagtatatg gcttgaaaat tgatcaaaag agatagaaac acaaaaaaga gaatgcaaca
    27241 aatcaatgtc gcattccctt ctgatatatt ttattcagca cttattttga actttctgag
    27301 gtgctagctg atgaacttgt ggagctggaa gattcttctt ttgaagagtt gcttgtgcta
    27361 ctggagctac ttgagctgct agaactgtct gaagagtctt tttcagaact agaagacgct
    27421 ggatctggtc ctttagagta aattacgttc acaaccattc ctttggtaat tgtcgttcct
    27481 gcccctggta ctgtacgaat cactttatct ttatccaccg tgtttgaata ttcggaagtc
    27541 tcatgcccga tatattctgc accgacacta gctaaataac tttgtgcttc gctttttgta
    27601 tagccggaga tatcattcaa tttaggctct gttccttggc ttacgacaaa attgatgtaa
    27661 gtttcttctg ctacaacttc acccgaggct ggatcctgac tgatgatcga acctgatggt
    27721 acagtgtcgc tatagtcata agtagcacta atattattga tattgaatcc ttgtgtaaca
    27781 agccaattac gaacagtttc gtagttttct cctacatgac tactcaaagt cactgtttct
    27841 ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag gatcgacttc tgtatcttct
    27901 gatggagatt gcgaaatgat cattccgctt tctacctctg aactgaattc ctcttctttt
    27961 tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg cttcggcatc ttcataactt
    28021 ttaccactgt aatcatctaa tttgattttt ttcgtgccgc tactaatata cagagtgact
    28081 tcgcgttttt gcttgactgt cgttcccgct gccgggtctg tcttcactac attaccttct
    28141 tcgattttgt catctgcaat ttcttctgtt tttgttgcta cttctaattt cgcttttgcg
    28201 agtgtttctc tagcagaagc ttcagaaaga tcagaaacat caggaacaac aacttctcct
    28261 cgcccgccag aagcaaagaa tacagctgtt ccgattccta aaacagcaag aatagctaat
    28321 aggatcagcc accatttttt ctgtcctttc tttttaggat caggcagaac ttcttcctcc
    28381 tctggtaagg tttcgttttc tggcttgtct tttggcagag gcatagattt gaatgaatca
    28441 ggcattggtg catcttccgt aaggggtgtg ataacttttg tttcattatc catcacatga
    28501 ggctgccatt tttcttcgtt tgcacgagct ggtgataata ctgtagaaag atcatcagac
    28561 atttcctcgg ctgacttata acggtctgca ggttctttag ccgttgcccg taaaatcacg
    28621 ttttccagtg cttgtggcac atttggatca agtgctttta tagatggaag atcatcttga
    28681 aaatgtttta aagcaattgt tacagcagat tcaccatcaa acggtacgct acccgtcaac
    28741 atctcataaa ggatgatccc taaagcataa atatctgact gcttcgttgc catacttcct
    28801 ctggcctgct caggggacag ataatgaaca gatcctagca tcgtattcgt ctgcgtgatc
    28861 gatgtttcag ataaagcgat agcaatcccg aaatccgtga tttttacaac accttcatta
    28921 tcgatcagta cgttttgggg tttcaaatct cggtggatga tttgatggtt atgagctaaa
    28981 gaaatagcag aaaggatctg ctgcataata tttactgctg tttcataagg aacaggataa
    29041 tgtgtttgga tatatcgttt caagtccatt cctttgacgt attccatcac cagatactgc
    29101 atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt ttggatgaac gagttctgtt
    29161 gctgctaaag cttctctctg aaatcgtcga atcgcagtct ggtcattttg aaagtcaaat
    29221 cgtaagactt taactgctac atcacgatcc aagattaaat cgtgcgccaa aaatacattt
    29281 gccataccac cgctaccgat atttccagtg atttgataac ggccatttaa ttttttgccc
    29341 aactcgatca tacactgtcc tccttatatt cgataagaag aacggtgata ttatccgctc
    29401 cgcctgcttc attggcacga tcaatcagct cagttacttt atgagacaat gggccttctt
    29461 gattgatgat cgttcctatt tcttcttcag acagcatgtt cgtcaagcca tctgaacata
    29521 acagcagtcg atcttttagt tgccaaagat gagtagaaac atctacttcg actgttccag
    29581 gcatgccgac agaacgtgtt aaaatatttt tccttggatg gttcactgcc atttcttcgc
    29641 tgatttctcc tgatttgact agttcattga ctaaagaatg atcctccgtc aattgcatga
    29701 ttttatcttc acgaatcaaa taagctctgc tatccccaac attggcaatc gtgaaccagt
    29761 catctgacag agcggccgct acgattgttg ttcccatacc gttatattcc ggctgttctt
    29821 gtccacgctg ataaatcagc atattttctt cttgaatcga ttgaatgaac cattgggcga
    29881 ttttttcatc gtcaacagct tcttgttttt cccaagcttc gcctagattc gttaccgcca
    29941 tctgactggc aatgtctccg gcacgatgac cacccatccc gtctgctaat acagcaagct
    30001 tgagacctga acggctggta aatacactgg catagtcttg atttgtgtta cgtcgtcttc
    30061 ctacatctga ttgatattca atctgcattt tttcacctca ttactttttg cgcaaacaac
    30121 aaatgaaaaa tccatctgtg taaaactgat gcggatacaa agtcaacatt ttctcttcga
    30181 ttgatgattg tagcatagga ttggtcaaaa catcaatcct ctcaaaatca gggtgtcttt
    30241 ccaagaaagc agaaacaacg tcttggtttt cttcttttaa gatcgtacaa gtgctataag
    30301 tcagaatacc ggaagacttt aaagttggtg cgcagctttc taaaatttcc aattggattt
    30361 ttggtaaatt cgctaattca tccggctgtt ttttataacg aatatctggt tttcgccgaa
    30421 gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg atcaaactgc tctgcttcga
    30481 actgtttact gacttctcta gcatccatct tttgagcgta gacagcagaa gagacaccta
    30541 gacgtgctgc attatcttca atgagtttga ctttgtgttc gtgtacatct aaagcgacca
    30601 cttctccacc gcatgacgga tctaaaaaag aagcaatatg cgtcgtctta cctccgggtg
    30661 ctgcacaggc atctaagaca tgatgttcag gctcgatttg catagacggc gctacaagca
    30721 tcgaactttc atcttggatc gtcatgacgc catcgtggaa caatgagcta gaagctaaat
    30781 gccctttttt cgctactata ccgtatggac tgacttggct tttttcagct gtgatctctt
    30841 cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg gcgtgtatct actcgggcac
    30901 tagcatggct aggctgatat agcgataaac cgagcttttc agtttcttcg tatccgattt
    30961 gatccaccag tcgtttcgtc atccatagag gcaggctgat tttgacagaa agtctttcga
    31021 taggatcagc aatgccttgc agatctggtg ctccttgacg ctgataattc ctcaagacac
    31081 catttacaaa tttccctgtc ccaggatttc cttttacttt tgcgatttcg accgcctcgt
    31141 ttaaaatagc atgtgcaggg actttatcta aaaattctaa ttggtataca gaaagataaa
    31201 gaagcatctt gacccagtca tccacttttt ttgctttagc gatcaatggt gcaacgtaaa
    31261 attccaatag tcgctgatgg ctaatcgtac catagatcaa ttctgtaaat aaacccacat
    31321 ctttttgatt tagctcgctt tgtttgatca tctcattcaa caaaagattc gagtaggcgc
    31381 cacccttgtt cactcgctct aatgtcagta atgccatata tcgtactgat tttttcattt
    31441 ttttagggat ttttttcatt atttcacctg ctgaccaatc tgaacttgct gaccgcttcc
    31501 gttaaggaaa tcatgtacgg cctgttttcc tttaccagct ggctgtaatt cattgatggc
    31561 taagacggtc tgtttaccgc aagcaatcca tagatttttt ttgtctttcc ggatgatcgt
    31621 accaggtgct ttgtctgtag tttctgccaa tacttcaacc gataataatt tccagcgtat
    31681 gccctcatag gtcgtgaatg caattggcca aggacgcatt ccgcgtactt ggttgtcaat
    31741 ttcttctgca gttttatgcc aatcgattgc ttcttgttcc cgtgtgatgt ttggcgaaaa
    31801 agttgcttct gactcgtctt gaggtactgg tttttgtcca tccaaaatat tgggcaatgt
    31861 ttctagcaat agctttcttc ctaaaaggct aagcttttca aacatcgtcc ctacatcatc
    31921 ttgtttagtg attggtatgc tttcttgcgc atagattccg cctgcatcca tttttttgat
    31981 catttccatg atcgttacac cagtttcttt ctccccattc atgatggcat aatgaacagg
    32041 cgcacctccc cgatatttag gaagtaaaga agcatggaca ttgattgccc ctaattttgg
    32101 tacttgcaat aacttttcag gcaagaattg gccaaatgcc gcagtgacga tcacatcagg
    32161 caccaattca atgatttctt ccatttctgg cgaaccggag attttctctg gctgcagcac
    32221 acggataccg tgcttcagag ccgctttttt taccggtgtc ggcgtaatta ctcgtttccg
    32281 cccaactgga cggtcgggct gtgttaccac tgcctggatc tcgtaacctg attctatcag
    32341 cccttcaaga atcggcacag aaaaagcagg tgtgcccata aatactagct tagtcatcaa
    32401 gatgttcctc catatattct tcaagttctt cttccgggat ctgctgtatc attttctcaa
    32461 tgaacaagat accgtctaag tgatcgattt catgctggaa ggcacgggct aaatagccaa
    32521 aagccgtcac ttctatctct tctccgtctc gatcataata acgcacggtc acttcatctg
    32581 ctcgcttgac cgttccatag acatgcggaa tactgagaca accttctacg tcaaggcttt
    32641 caccttttgc ttcgatgatt tctgggttaa tcagttcaaa tttctcgcct tcatctactt
    32701 cgatcacagc aattctcttg ttttgtccta cttgaggagc agcgatccct attccgtcat
    32761 tcgcaatcat tgtctcatat aaattgtcta ataaagcgat tgtctcgtcc gtgattacat
    32821 cgattggctg agcagttctt tttaatttat cattagggtg gatcaatata ggatagcgca
    32881 taatttggcc ctttcttaaa taaagtttaa tggttcgttg tcaattgcca caaaaagacc
    32941 ttgtcgctgt tctttctggc ttccattcaa aatttcatcc aaaacatgag gaagattcgg
    33001 ttcatgttta tatttgatga ttagttgata ataatatcgg tttttcactc tcaaaatcat
    33061 gctgggcgtt ggccctaata gcaagctttg agggcttaac acttctttta gctgattggc
    33121 aatctgaaag attttctttg ccgctacttg ttcttcagga tggctggcgg ttattttcac
    33181 agtaaagtaa taaggaggat agcctccacg atgccgtaca tgcatttcct gctgataaaa
    33241 ctgctcataa ttttgttttt tagccaattc tatggcgtaa tgttgaggat tgaatgtttg
    33301 gatcacgact tcgcctgctt tttccgctcg ccctgctcgt cctgaaactt gggtaagcaa
    33361 ttggaatgta tgctcactag aacgaaaatc cggtaaattc agggaggtat cagcattcaa
    33421 caccccaact aatgtcactt ctggaaagtc caaaccttta gcaatcattt gtgtccctaa
    33481 taatatatct gcttcttttg caccgaattt ttgtaaaatc tgttcgtgtg ccccttttct
    33541 tcgagtggta tctacatcca tacgcaaaat cctagcttgc ggataaagtt ctcggagttc
    33601 ctcttctact ttttgagtac ctgttccata gtagcggatt ttattgccgc cacaattagg
    33661 acagcgattg ggaataggtt cttcatgtcc gcaataatgg cagcgcattg aacgtgtatc
    33721 catatgcagt gtaagagaga tatcgcaatt aggacatgga agaacaaatc cacagtccct
    33781 acacatcaca aaagacgaat atcctcgacg attgagcagt aggacagttt gttctttttt
    33841 gtctaatcga ttttgtattt tttcctgcaa attagcagaa aaagtagagg tccgatgatt
    33901 ctgaaactct tcacgcatat ctacgatctc aatagctgga agctgtgcag ctgctttggc
    33961 tcggtggttt aactgcaata actgataaac gcctttttga gctcgtgctc ttgattctaa
    34021 agagggcgtc gcgcttccta gaactattgg gcaatgatga tatttactgc gccaaattgc
    34081 tagatctctc gcatgataac gcggtgtctc atcttgtttg taacttgatt catgttcttc
    34141 atcgataatg atcagcccga tatttttcag cggggcaaaa atagcagatc gtgcgcctac
    34201 tactacttgc gcttcttccc gctcaatctt gcgccattca tcatattttt caccttggga
    34261 aagtccgcta tgtaagaccg caactgattc tccgaagcgt cctttgaatc gctcgaccat
    34321 ttgcggagtc aatgcgattt caggcactaa cataatagcc gttttatttt ctgacaaaac
    34381 atcagcgatt gcctgaagat atacttctgt tttcccgctg ccagtgattc cctccagcaa
    34441 aaagacctga tctttttgct gctgacctgc tgtgatgatt tgttcgacag catttttttg
    34501 ttctgcattc agttccaatg ccgtcgtttg gtcaaatact cggtctttat aagggtcgcg
    34561 ataacgttct gattctataa actccagcca gcccttttct tttccttgat tcaagacagc
    34621 agtactgatt cctttatttt tgaaataagc aattggttct tcttggctca gttcagataa
    34681 acacaaaaga agttcttttt gtttcttggc attttgccgt aattttgccc attcttcttc
    34741 gatttgcttt tcagttaaca aagaacggac caaacgaatc gtttttactt tatttcgtgt
    34801 atggacttca tatttgatat ctactaattg ctcttggcgc cagcgaatca attgagaaag
    34861 gctgccttct tcttctgctt ccttccagga aatcacttct cgctgatcaa acaatacctg
    34921 aacttctggt gtgtctgcca aaggatagat caatttatca tattctgctt tcatcacact
    34981 cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa gtaatttttt tcatataatc
    35041 agctaatgaa agtaattctt cattgaccac cggagcaagg tctagcaaac gaataactgc
    35101 cttcaaagat ggattagctg attcttctga tttttggata gccataacaa atccttggac
    35161 atgacgattg ccattaccaa aagggacttc tactcgcatc ccgacttgca aagctgtttc
    35221 catttcagag ggaaccaaat aagtgaatgg ctgatcggtc tgcatagtag gtacgtccac
    35281 aatgacttca gctgttaatg tcatggttcg tttcctcctt tttttgtctt ttcttatcaa
    35341 gcgacaaaaa gttccttgcc tattttacta gagatcgatg gatttgtctt atcttctgcc
    35401 aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag aactgtgtca aaaagttcag
    35461 acacagcctt ttctaccaga caataagtgg cgaatgtttg aaaaggaaac agctgggttt
    35521 gcttttcttt ttagatgttc gctctatttt tctttattac attttttgct cttcacggat
    35581 acgtgattcc aattcgtgtt gttcacgctc tttttgtgct tgacgttcct cttcttccat
    35641 cttcaaacgt tcacgtttta attcaggatg tggatcattg actacatttc ctgcatcgat
    35701 ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa gaatctagag taggctgtgc
    35761 acttgcatcc aattcatgcg cgcgtttact tgctaaaatc actagagaat attttgaatt
    35821 tacacgatct aatagtgagt caattgaagg ttttaacatc ataagactac atctccttta
    35881 acattttaat atatttaccg attacgcgat ctactcgaaa atgttcactg gcaataatgt
    35941 ttttgattcg ttcaactgct agcggcactt catcatttac aacagcatag tcgtaaagag
    36001 ccatcatttc gatttcttct tttgcaactt tcattcgttt ttcgattact tcatctgcat
    36061 ctgttcctcg gcctacgatc cgtgatttta attccgctaa atctggcgga gtcaaaaaga
    36121 tgaatacacc atcgggcact ttttctttga cttgttttgc tccttggact tcaatctcca
    36181 agaaaacatc ttttccttca tccaatgtct tgttgacata tgacaaagga gttccataat
    36241 aattcccgac atattctgcg tattccagca tctctccagc ttcgatcatt gattcaaact
    36301 cttctttgct tcggaagaaa taatcaacgc cttcgacctc cccttcacgc attttacggg
    36361 tagtcattga gatcgaatac tgaaaatcat tatcctcact ctcaaaaatt gcttttcgta
    36421 ctgtgccttt tcctacaccg gatggaccag acaacacgat taataatcca cgctctgaca
    36481 tgacgacgtc ctttcaacta gtctttttgt acttatcgtt tattttgcac tttttttctg
    36541 caactttcaa ggttatcttt aattatagct agaaattggt aaaaaagcta ccctgtacca
    36601 agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca taaacagctt
    36661 ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc aagcttttga acgccgtgta
    36721 taagaggtcg tgaagaagcc gattagtttc gagtatgaag aaaaattttg tgaaaatagt
    36781 ttctcacatt tttgcataaa tttggcttaa taccgagaaa atggtttttg aacatcactt
    36841 attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca acctttaaat gtattcctag
    36901 agcaaagaag ctaagcgaag aaatccaatt ctgtttattt attgtatttc tttgttcagc
    36961 atccttgcta aaagcccata ttggacaaag tattcactac acccatgatc tcatcttttc
    37021 gagaacgtgc tttttctgtc ggatcttcta cctcttctgt gtcaattcga acaataaatt
    37081 tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat aaacagttcg ttctcattat
    37141 agtctgcaca ggcatctttc catacgtcaa agccgttttt ttcagaaggg atatcccgtt
    37201 taaccacagt ttttccactt aattcgtgga acgttacgtc ataatatttc attatctcta
    37261 cctctttcgt cattcaatat tttgtacttg ttctctgatt ttttctaaga tcgtcttaga
    37321 ctggacgact tgatttttaa tttcgattgc atttgatttg gaaccgatcg tgttgatttc
    37381 ccgattcatt tcttggatca ggaaatctaa ttcccgacct acaggacatt gtgcttcgat
    37441 aagttcatct agtttttgta catggatcgc cagacgatcc agttcctcgt gaatatctcc
    37501 gcgttccaac aagatggcta gctccgtcaa caaccgttgc tcatcgactt tcgctccaag
    37561 aaattcctcc agcttttttt gataccttat ttgaaattcc ttttcataga tttctacaaa
    37621 actatcgagt ttttttagta cttctttgaa ttcttcagta ttctttttca acactaaagc
    37681 taaagcttga ccttcttttt ctcgactcgc ctcaatagaa tcaagtgcgc ttttcaatgt
    37741 atctagagct aactgtgcca attcttccat gctctcttcc ggtttttctt ctaccgttac
    37801 gaagttttcg tccagcacga agcgttccgc catccgacta attgacactt gattttgact
    37861 accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata agtgaatcaa tcaattccca
    37921 gttgatgacg atctgttttt cgtttttgcc aatataagct agattcacaa atacttcgat
    37981 tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa tcgttttcaa caaagttcag
    38041 gattttagga cttcgtattt gaacatctag aaaacgctgg ttgacacttt ttatttcaat
    38101 atctaactga tacgcttttg tttcgcggat ggctttgcca aaaccagtca tacttttcat
    38161 tcgacagggt ccttcctcat tacatatttt ctattgcttt ttgcagttgt tcaaactctt
    38221 cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc tggcgcccaa tctcgaagat
    38281 cgaattttgg cgggcgacca ttccagctga ctaggttcag ttctttacgc caccccttgt
    38341 tgttttctga caatatagcg atttcttcta cgatttcata tgaaaattct tgtgccatgg
    38401 ttgttcctcc ttgagataat ataaatatag gatcagtaat gtgtcaactg gttgcttaag
    38461 caattcatgc tgcaaacgat ccttgcgttt tccttgtagc agataatcaa aataaacagt
    38521 tttcgtgcgc tcattttgta ttttttgctg gtattttcga taccttcgcc attcttcagt
    38581 acttaattga ccaatttgtg ccaataaatc atccggcata ctttttatat cttgttggca
    38641 gatcatttga atcatcatgt ctacttgata gatttcattg ggcagtaaaa aatgtttttt
    38701 tgctaaaagt tctagcatcg ccaatccgca tgtctctggt acgaccctgt tcttatataa
    38761 attacgcagt ttttgccaaa attttatgct tttgaaaaaa gataattcta actgaatttc
    38821 ttttgttaag taagacaaaa atcctcgcca gtatgttctt gcaggtttaa cagaatgaaa
    38881 tgtataccag ttcccatagt aatagcctaa tcgttttttc atttccagat agcctaattg
    38941 taaatttaat tggttccttt ggctatcaaa aagcagaaag ctgcctagtg tccacaatgt
    39001 ttgacatttc caatggataa aaatgtctgg catacgaatt tttttcgctg ggcctggccc
    39061 ttgcacatct acgacaaatg cctctgttgc tcctttgtta atcgcaatat caataggtat
    39121 tttgttgcga tacccaccgt ctgcatattt attttttccg atctttcgat aagccatagc
    39181 gggataaaat gaagcagagg cgagtatcca atctggtatt tcttctgttt ttgtctgttg
    39241 gatatcagtc actacttccg ctagttctgg cagtttagta gacaccgtat ataaacgtat
    39301 tttgggatta tgtttgagta aggacaaatc caaattgtct ttgaccatct tttccaatgg
    39361 agcagaagaa accccgcctt caattagtgc tgttttcgtc atttggcgtc tttctcgata
    39421 gaagcgttca cgaaggtctt caactgcagc catttctggt aacgcaagca cttgtcttgt
    39481 cgacagcttt ttccataaat tcacagcttt tttcatatct ccttgtaaaa tcaatgcgcc
    39541 gttcaacgca cctaccgagg tacctgtgat aatctcaaag ttgatatcat gttccttcag
    39601 cgcctgccac acaccaatct gataaggacc gtgcgctcct cctccaccta aaacaagtgc
    39661 tgtatgatag accagctttt tatttaattg tgtggttcct tgatagccgt ttttatgaaa
    39721 aatacgcaac cattcttctg atagaggaga ttgaaataaa aaacaacagt tttctttaat
    39781 aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt ttccattcaa aagtttcacc
    39841 ttcaatcaac agattattaa aaataacatc tcctctactt ttagcaatag taaaatagac
    39901 ggtatatttt ttcgatactg ctttaaaagc acattgcttt tttgcagaac gccaaaaagc
    39961 gtctctactt tcttgatgac tttgaaaaaa tggaaggggt tgttttgctt gctggatagg
    40021 cgaatacagc gacattttct gtgaaaagta aacttttttt atctccatcg cgctctcctt
    40081 tttcttcaag tataccagta cgtcataaaa aggtcatgag tctcgtattc gactttgtag
    40141 attccataag aaaacaattc ataaaacctc ctttaaataa aaaaatacaa aaatcacaaa
    40201 aattaattga aaatgagagt gttttcaatg aaaacgtgat tttgtaatgg aattttaaaa
    40261 taaaagaaac aagctttttt aatgcaaatg ttgtaaaata aaagagatta agaggaaata
    40321 agaggaggaa catgatgact gagtcagttt atgtacatat tgataccaca agtaatgctg
    40381 ttttaacaaa agggctgact gctactgact ttgcaaacag tatcgtgcat tttcctcaaa
    40441 acttgctctt gcttgatcca tctgcttctg ctggagaata tgaatcccat acagggctga
    40501 aagtaatccg tggtacagaa aatattcagc gtttcttttc ctcttctcgt aacaggcgtg
    40561 gattcgatga attgaagtgg atcgacttta ctgatttaac gatgctgaaa gaattgacac
    40621 ctttagaaat ttcagaatta ttatattttg gtcatatgaa aacacatctt cattcgccgt
    40681 ttttttataa actacagaat aattttgtat acttcgatct taatgatcag ctgaatcgga
    40741 tttattatcg ctatttagat gaattttata ggatttttgc tagtaaatta agttcgatct
    40801 tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa
    40861 tcagtgtgga attattgaaa gaaatgcgta atttgatgca ggaagggatc attttttctt
    40921 ttgatcaagt tggtttgatc gatggtaaat atcgtatccc aatctatgtg attgaagatt
    40981 atatttggaa attaaaaggc acccggtatc gagaagagga aatcatcgct actttaatct
    41041 actctgtcac cgatcgacac tggcaattgg tagaagatgc cgatctttct tatctgccat
    41101 tgaagtagat ctatttctta tcaaaaaata aaaaggaaac aagaaactag gacatgattc
    41161 tgtctcaagt ttcttgcttc ttttttattt acagctcctg tcgtttatct ggcacaaaaa
    41221 tcgaaggagt cgtttgttgg atccctaata aaacgatgat cgttacaata gctgtactca
    41281 acccgctggc accattcatt acgaaagaaa agagccaagg attcatcccc catagtgcat
    41341 acgctcccca gaaaaccact cctgcaataa aatgccaaaa atatctggaa agtgcgccaa
    41401 tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt attatcgtct acatagcctt
    41461 tttggacatt tgaagccatg agccctgctg cgcctgcaaa agtataggca atcgggtact
    41521 caatcaacac ttgaacgaca cttaaataat aaacttgtcc caacggaaaa tgtaggatgc
    41581 cccaaatgaa acctgccagc atccctgcct ttgtccctct tcttaacgca aaaagagtca
    41641 atggaatctg ccctaatgaa atagaaaaac tgctgccgat ctggatcgga atcaacgaca
    41701 acaccatcgc taacgctgca acaatcgttc cttctaccca aactctattt tttcccataa
    41761 aaaaacttcc tcctttgaat aaaaaagtca caaaggagga agcagctttc gaaaatagtc
    41821 aaacagctgt ttattcacaa ttcctacgct cgcataaccg atacaggtac gaagggttta
    41881 gaaatagatt caatctcagc ccaattggac tcccctttgt gagtttattt attatttatt
    41941 ttttgtttca aacaatggac taactggttt gttttcatgg atacgtttga ttgcatctcc
    42001 cattagtccg ccaacactta cttcatcgat tttgtcgatt ttacgatctt ctggaagata
    42061 gatcgagtct gtaacaacta gacgctcgat agctgaatct tctattcttt gtaaagcagg
    42121 gccggataat actggatgtg tacatgaagc atacacacta gttgcaccag cttctttcaa
    42181 agcattggca gccaatgtga tcgtacctgc tgtatcgatc atatcatcga tcagtacaca
    42241 agttttgcct ttgacttgtc caatgatatt cattacttct gcaacatttg cttttggacg
    42301 gcgtttgtct atgatcgcaa tcggagattt caaaaattcc gctaatttac gtgcccgtgt
    42361 gacaccacca tggtctggtg aaacaacgac aacatcatcg cctttgattc ctttttctaa
    42421 gaaataattg gcaataagtg gcgcacccat caaatgatcg actggaatat caaagaaacc
    42481 ttggatttgg actgcatgaa ggtccaaagt cagcattctt gttgcaccag ctttttgaat
    42541 catgtttgct actaatttcg ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg
    42601 cgcatagcca taataaggca tgactacgtt gattgttttt gcacttgctc gtttcagtgc
    42661 gtcaatcatg atcagcaact ccatcaagtt atcattgact gggctgctcg ttgattgaat
    42721 aacatagaca tgcgatccac gaatactttc ttcaatgttt acttgaattt ctccatcact
    42781 aaattgagta acagatgatt ttcctaactc gacgccgact gctgctgcaa ttttctctgc
    42841 taatgggcga ttggaattta acgcaaaaat ttttaatctt gggtcaaagt aatgttttga
    42901 catggggacc tccactttct ttttcacaac tctagaattc tacctaataa atagtagtca
    42961 tattttttaa ataaatcaag tgattttgca aaagtcttag tttagataag ggagtttttt
    43021 tgcatatcct tctttattga cttgtcttgc tctcgcaatt gccagcgcat attctggaat
    43081 attgtctgta attgttgacc cggcagcaat cgaactgttt ttagctacct cgacaggtcc
    43141 gatgatattc gtgctagaac caataaagct gtggtcgccg acagtcgtat gatgtttgtt
    43201 ctttccatca tagttgacga agacaacacc acatccgaca ttgatttctt ctcccagcgt
    43261 agcatcacca acataagtca agtgaccgac tttagttcct ttgccgattt gagcattttt
    43321 cacttccaca aagtttccga tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg
    43381 tgcataaggt cccacatctg catgtttctt gacatggctg ctttcaatga ctgagttttc
    43441 aatgacgacg tgatcctcaa tcctactgtc tacgattttt gaatgtgacc cgatgacaca
    43501 atcagaacca atgactgtat ttccttggat ttgtacacct gcttcgatca atgtgtctgg
    43561 accgatttct acgcctgcat cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt
    43621 gaccatatgc atctggttaa ttcgctttct catgatctca tttgctttag ctaacgcgat
    43681 ccgatcattg actcccattg attcttcaaa atcatccgtt tgataagcag caactgtatg
    43741 gccttcttct tttaagattt cgatgatatc tgttagatag tattcacctt gagcattgtt
    43801 tgttccaact ttgcttaacg catcgaacaa agcttcgttg tcaaaacagt aagttcctgt
    43861 attgatttct tgtacaagag cttcttctgg tgttgcatct ttttgttcca cgattttttc
    43921 tacgatccca atatggtcac ggatgattcg tccatatcct gttgggtttt ctgcttgtgc
    43981 cgtcaagatc gttgcacttg cattttttcc ttggtgatat tcaaaaagat tgttcagcgt
    44041 ttcagtagtc aataatggtg tatcgccact gataactaac gttgttcctt tttttccttc
    44101 caagaaagaa gcagcttgca aaacagcatg tcctgttccc aattgttctg cttgtaacgc
    44161 atatttactg cgttctccta gttgtgcttt aacttgttct gctccgtgtc caacgatcgt
    44221 aatcacttca tctggtttcg tttcactgac ccgattaatg atatgttcta ccataggttt
    44281 accagaaacg ggatgtaaaa ctttatataa ttttgacttc atgcgggtac ctttccctgc
    44341 cgccaaaata attgcataac gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat
    44401 ttcagtttat cccagtatac ccattttttc aacaaaacaa gtgattttct tttatcccag
    44461 cgttttctgg ataaaaaaat agatagacca taacgggcct atctatttgg taaccggtgc
    44521 tctcctgcca actcctcggt cacaagtcac actactcata aaacatgaaa agctgttttt
    44581 tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt acaacctctt cattaaacgt
    44641 ttttcaatca gctgaccttc ggtattagct caataaacgg caaaatatga ggagcaattt
    44701 ttccgtttat tgagctaata ctcaggacag gacgctgatt tcacaacctc tagataaacg
    44761 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gaaaaaatgt ggaaagccat
    44821 tttcacaaaa tttttcttac tactcgaaac taagcggctt tttcacaacc tcttattctg
    44881 aaaaataatt tcctggcaca accgtaatat ttttcgtttg agtatctaca tctttgacat
    44941 aaagcagtga cgtataatca tcgatggcgc gatgaccgtt gaattttgat tcggcaaata
    45001 cagtgatgcc aacaagttct gattcgaatt cttcaatcaa gctcttcatt ccgttgactg
    45061 ttccgccgcc tttcatgaaa tcatccacta caaggacacg tgaaccacgt ttcaaacttc
    45121 tcttagacag ttccatcttt tcaattcttt cagaagatcc agacacatag ttgacactta
    45181 ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat aacgaatggc gcattcagat
    45241 aataggacac agcttgggca ataggtacgc cttttgtggc tacagtcatt acagcatcga
    45301 ttttttcacc aaggtattta gaagcaatga ttcttccaac ttgacgcagc agttcaggtt
    45361 ctcctaacaa atcagagaga taaacatatc ctcctggaag cagacggtct tgttctgata
    45421 gacgttctgc tagagattca atatattttt tcgcctcttc atatgaaatt tcagggatga
    45481 acaatacacc acctgcagca cccgggattg tttccaaggt tccataccct cgttctttaa
    45541 atgttttctt gatgattccc aaatcttcac tgatagaaga tttagcagat tcataacgtt
    45601 cggcaaagct tgttaaggaa atcaattcat gcgggtgatt caataaatac tgtgtcatgt
    45661 caactagacg ttcactgcga cgtactttca cctattccaa ctccttttaa gaaattttat
    45721 cgttttacat tatataagtt tttcttcaaa aattcgagca ttttatgaaa aaataagaaa
    45781 atagttcggt atttattaaa ataaaaagaa gcctataaaa aatttttcgt ttttataagg
    45841 cttcttttct ttataattta gttatttttt cttctgaagg caaccaatat tcgtttgatg
    45901 atatttacaa tcaggaacaa agcaataaag actaatgtga ttgttgctcc tggaggtgta
    45961 tctagataaa acgagctagt tagtcctgac agcatcccta gaaatcctac acaaacactg
    46021 atagcaatca cgacattgaa gcttttgcct aatcgcatac cgattgctgc gggaagaacc
    46081 atgattgcgg atatcaaaag tgcaccggca atcgggatca tcacagcaat agccacacca
    46141 gtaatcacat tgaacatcat cgacatcaaa tgaacgggta gcccatccac gtgggcggta
    46201 tcttcatcaa aagtcagaac atacatcggc cgtttgaata aaaagaacaa tataccgatg
    46261 gcaacgaata agattcctaa aaagatgact tgctcccatg taatggtcac gatcgaacca
    46321 aacagatagg attggatact tgttgctgaa ttccctccgc tcaaattcat caatactaac
    46381 gctagcgcca aaccaccagc cattaaaatg gcaatggaga tttctgaata ggttcggtag
    46441 atcgttcgca gatactccaa tatcacagct gctaatacaa cgactagcat ggtcgtaagt
    46501 gtaggattaa ggttcaaaaa gaatcctaac gctacccctg ctaaagagac atgagaaagc
    46561 gtatcagcca tcagcgattg tcttctgatc actaaaaaca cacctagcat cggggcgatt
    46621 ccggcaatga agatagcggc aagaaacgct cttctcatga attcatatga aagcaacgcc
    46681 attgagaatc ctcctttctc accagtcgga tctgtctgtc cgcatactgt ttgatatctt
    46741 catgatcatg ggtgatcatt agaactgatt tcccatggac atgcgcacta tgtcggagaa
    46801 gacgataaaa ttcatttctg gattcttcat ccatacctgt tgttggttca tcaagaacaa
    46861 ataagtcagg gtcagtagca aaaatacgcg ctaaactgat tcgctgcttt tgtccgccag
    46921 acaattcacc tattcgccga tttcgcatat cccacatccc tacagcttct aaagcacgct
    46981 gtacatgttg atgatctttt tcagagagac gcttgaacca gcggcctctt ggatatcttc
    47041 ctgaacggac taattcgatc accgtactag gaaaacctgc attgaaagat gcaacttgtt
    47101 gaggaatata accgatactt aatttttttc cttcttgatt tttctcagca atctttatca
    47161 ttccttttga aggtttcagt aatcctaacg atgctttcac caaggttgac ttggctgctc
    47221 cattttctcc agttaaaatg acaaattcac ccgcatctac atgataagag acatcttcta
    47281 gtacaggttc atcatcatag taaaaggtca aatcagatat ttcgatataa cgcaccttac
    47341 aacctccatt ctaaaactta attgatactt tcttttaaag ctttcagatt tttttccatg
    47401 acagaaatat aattttcgcc tgctttgatt tgttcattag tcaagctttc taaaggattc
    47461 aacacttcta gcttcactcc tgtttcattc gacaatgtct cagctacctt cgaagaggca
    47521 ttttcttcaa aataaatcac tttgatgttg tttttcttca caaattcttt tagctcagct
    47581 aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg aaatcgctac ttgttttaag
    47641 tcgtattgat tcgctaaata agcaaaagca gcatgctgag tgacaaatgt gcggtttgtt
    47701 gcatctttta gctcatcgga gtatttttga tccagtgctt caagcttttt gatataagca
    47761 tcggcattct tcgtaaaagt ttccttttta tctggatatt tttcgcctaa ttcttcagca
    47821 atcgttctga cttcttttat agctaatacc ggatcgagcc aaacatgtgg atcgtattca
    47881 tgtgaatgac catgcccttc ttctgattct tcatgttcgt ctgcttcttg cgattctaaa
    47941 cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt tgctatccac tgaatccttt
    48001 aacgaatcca caaaaaattc catgtctgaa ctattataca cgaaaacatc tgcatcggaa
    48061 atttctgctc tttcttttgc acttggttcg aaatcatgcg gctccgttcc agcagggatc
    48121 aaaagtttca cgtttccttc atcccctacg atctcttttg taaaatcata catcggataa
    48181 aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt ccttgttcgt atttccacat
    48241 gctgcaaaca gtaaagcacc tatcattacc gtagctgtca aaagatattt tttcatttat
    48301 atgctccttt caatgaacaa atcggaattt tacgatttat taacgtgaac taatgtatca
    48361 aaataaaaaa acacagtcaa tagaaatcca tcaatttctg atttaagcat gtatattctt
    48421 gattaaatcg taaaatggat gagttgctgc tcatatctag ccatttcact acaataaaaa
    48481 actgaagaat accattttag gattcctcag tttttcatca cctattttac ttcttatatt
    48541 ttattgcagg gttcgtacta aataaacttc ctcacaaaaa ccttttaacc cattatatac
    48601 tctctgcgct cttgaataat gttgacacaa ggcaaaaacg gttggtccgc ttccactcat
    48661 caatgcagca tctgctccgt acttgatcat acgctctttg atttgatgga tgactggatg
    48721 ccgctttccc gttatatctt ctaaactgtt tcccattttt ttgatcatct gctgataatc
    48781 ttgctctcgg atggcttcag caagtccgtg gatgtcttga tgttggatgg cttgcgtatc
    48841 tacttctcta aacactgtac gtgtagagac actcattctt ggtttgacca acacaaccca
    48901 gcactgtggc atagaaggta atacttggat ttcttcccct ttgccaccga caaatgccgt
    48961 acttccgtag acacagtaag gaacatctgt accgacttcc aaaccgattt ctgccagttc
    49021 ttctaacgaa cagcccagat tccataattg gttgatccct cttagagcag ctgcacagtc
    49081 tgtacttcct ccgcctaatc cagctgctac tggaatattc ttcttaacaa agatcttgac
    49141 accggttttg atattgtatt tattttttag caataaagca gcttgataaa cattgttccg
    49201 ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg attttgtctt ctgttatttc
    49261 ttcaaaaaat agatgatctg ccaagtctac gctcgacatc accatttcca actcatgata
    49321 cccatcttgc cgtctatata atacatccag tcctaaattt atcttggctg gcgctttttc
    49381 aatcaattcc atcctctcac ccattcgaaa agtctaagtc gcaagtattc tatcataggg
    49441 aaaaataaaa gtatagctta tgtctgccta gtggttgatt ttgtcatcgt ttcaacagct
    49501 ttcacagaat tttctcttca taatccaaac aagttctagt gattcttata attctgtgag
    49561 cacttcttct gccaaactcg gaacatttcc tttttctttt cctatcagac tgagtagctg
    49621 catggtagca aatccgaaat tacttccttt cctataagca aaataacgtc cttcccaatg
    49681 atcgacatat tttaatttct tttcataagc agactggaag gaatagaaaa aattaccata
    49741 attatatacg atatgcatga ctttttcttg aaagaaagaa aaatctgttt ctccaacatt
    49801 agctaatgga gctaagccta gattggcttc cgagtagccc attttctcgt atacaataaa
    49861 cagattggct aacagatagt cagctaattc ctcagattct ttaggtaaga cccgcaacaa
    49921 atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg atgaagccaa cgactttttg
    49981 atctttacgg acaataccga caccgctaga taatacatat gatttatcaa atcgtcccac
    50041 agagaagtat ttttctcgtg caccttgaag ccatttttgt gaaacttcat ttacagcttg
    50101 atgtaattct tccggcagtt gatcgtacca agtaaaatgg tatccttctt tcatcaaacg
    50161 ttgatattca agttgctgac tcagccgaga caagtcttct gttgctagat caacaatccc
    50221 tgcttcacct actttcgtga agtgaaaacc caattcatga agcatcacta cgtagctttc
    50281 tgatatctta taaaacgcaa gctgatagcc taaacaatct gcttgtttca taaactgatt
    50341 cgttgctgcc cgcatcattt taggattgcc aactggatct cctaaaacaa agcatttgtt
    50401 tcctttgatc tgataaccaa aaacgacttg atcttggtcg tcttcttggt aataaaaata
    50461 actgtaacct gacaagcgaa gctgatggct tgtagctgtg cctccgtatg tttccaataa
    50521 acggtcaaaa cggtcttttt cgtactcact gccaagcttc gtagtatctt cagctaaata
    50581 ttgataaagc gccactaaag ctagcaatga gatgcccaaa ccaataagcc ctgagaacca
    50641 cacatcatct gaaggaaaca aaataaaatg atttcctgtt attcgaccga ctaaaaagcg
    50701 tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa aagccgaaca agctagcatc
    50761 aaagattata gctccccaag aataaacgaa ttttgttcga taaaattctt ttctggataa
    50821 ccacacagct aacagaatca agacatatac caatatcaac tgccaagata acgtacgtgt
    50881 gattgtattt aaaataccaa aagatagtaa agcaatcgta ggcagaaatg cctttttgac
    50941 ttttactgaa agtgctctag caaggccgag taataaaaag ccaaccaata gattcactgt
    51001 ctgatctaaa aaattgaatg agaacggcaa taatacttga aatagccgac tgattgcaga
    51061 cagattagtg attgttgata gaagtaccat catgatcccc gcaaaataga cagcacttac
    51121 gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga atgttatcta aaaatcgatt
    51181 gattttgact cctgtatgtg tgatgaacaa tagaagtccc gtcataaaag gtagaacata
    51241 ataaaacaac cgataatata atagccaaac tactgctaca tcttgccgaa cagacaattg
    51301 actcattcct aagatcatca aaacgtcaaa agtccccatt ccacctggga ccatcgtcag
    51361 cattcctatc aatgtagcaa tcatgaacat aggatagatc gaaagcatcg aaatatctat
    51421 tctcatcaac ttgccgatga tcaaaaatac cgcaagggct cccgtccatt gtccaaagga
    51481 tgccagtagc agaccaagca agccttttgg ataaaactcg aagaacaatg tctttctctt
    51541 tagataagca aaaaagaaaa tgactggtgc taaaaaacta ccgccgaaaa gccagatcca
    51601 atagcttcga aaaatacttt ctgactgaat aaaaaagaca tcaataaatg taagaaacga
    51661 ccatacagac aaaccagtca gcataaatag tgcgactttt gatacagtgg ctaaaaccat
    51721 ttttctattt gtctgctttc cataaaaact agcccgcaga cttgctccta ccacaccacc
    51781 aaaaccggcg agattgttga tcgtgtttgt tacccacgca gcaagaagaa actcttttct
    51841 ttccattttt ggttttcctt gtttttctaa gactctgatc gtcacccaat catacaacaa
    51901 catcggagtg acacccagca gtccagccag aatcatgagc aggatcgtca tgcggctttg
    51961 ttgtcccatc ctttgccaaa tatcttgcca actcatgcca ttagcaatat ttgcgacttg
    52021 atttgccaca aagactaaca cggagccgaa aaaaatcagt tttaaaatca gactatgttc
    52081 ctttatccat tgcagcatca agtatcgttt atttttcaca ttttcccatt cctaacttgt
    52141 atacttttgt gtcatacccc aatgttatct tatttatttt aatttttcca ctttagacct
    52201 gttctttgct tgcgatgata gaaaaagaaa gatatcctaa tgctaaagga gaggataaca
    52261 tgaaagtagg atttatcggc acagggaata tggcacaagc tattattgat ggtttattaa
    52321 aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag tggacatttt gaaaatgcac
    52381 aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag taatcaggaa gttgcatcac
    52441 aatcagatat cgttctttta gccgtgaaac caaaaatcat tgaaaaagta ttggaagaac
    52501 taagagaata tagccagaaa gtcttattca tttctattgc ttcaggaaaa tcattaatag
    52561 atttagaaac agcgcttgaa gatcctcagg cctccatcgt acgtgtgatg ccgaatgtca
    52621 atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa tgaagctgcc acggaggaac
    52681 agcttcagca agctacgatg atttttgaag caatcggcag cgtctatcct ttagcagaat
    52741 cagatttcag tacattcatt ggccttgctg gcagctcacc cgcattcgtt tacatgctga
    52801 tcgatgcgat gggacggact ggtgtactga atggtttgtc caaacagaca gccactgaga
    52861 ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct ttcaagtgat aaaaatccat
    52921 gggaacttgt agaccaagtt tcttctcctg gcggtacaac tgttgcaggt gtagttgcct
    52981 tagaagaagc aggattcatc ccagcaatca tcaaaggaat caatacgacg atcgagaaag
    53041 atcttgagat gttgaataaa aaataatgat agcaatgttt tttcgtgcct tacaaaaaaa
    53101 gaagagctgt ggcttttgcc gcggctcttc ttttgtattt tttattattt agcataatca
    53161 gttgcacgag tttcccgaat aacgattact ttgatgtgtc caggataatc cagttcttct
    53221 tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt ctaaatccga gatttcttct
    53281 ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg cgtaacttga ttctacaccg
    53341 gcgaagctgt tcgaaatatt ttccagactt cttaaacgac ggatgtagtt ttctaatgat
    53401 tcacttcgcg caccaggtct tgctgctgag agcgcatctg ctgcagctac aaggacagag
    53461 ataacagaag tagcttccac atctccatga tgagaagcga tcgcgttgat tactactggg
    53521 ttttctttgt acttggcagc taattccgca ccgatctcaa cgtgagatcc ttcaatctca
    53581 tggtcaagtg ctttcccaat atcatggagc aacccggcac gttttgctaa ttggatatct
    53641 tcgccaagct ctgctgctaa gataccagct aattttgcaa cctcgaccga atgcttcaag
    53701 acgttttgtc cataactagt tctgaatcgc agacgtccga tgatcttgat tagatctgga
    53761 tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc cgtattcgcg aatacgttca
    53821 tccatttctt tacgagattt ctcgaccatt tcttcgatac gcgctggatg gattcgtcca
    53881 tcttgtatca gtttttccaa ggtcatccgt gcgatttctc ttcggattgg atcgaatccg
    53941 gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat cgataccagt cagcgtctca
    54001 agcgttcgaa tattacgacc ttctcgtcca atgatacgac ctttcatttc atcattcgga
    54061 agggtaacga ctgaaacagt cgtttctgaa acttgatctg ctgcgcagcg ttgaatcgct
    54121 aatgataata agtttttcgc tttgcgatct gcttcttctt tggcacgctg ttcagattct
    54181 tttaccatta gagttaactc atgattcagc tcttcttcag tcgatttcat gatgacatct
    54241 cgtgcgtcct cttttgataa accagcaatt ttttctagtt ctttttgttg atcttcaatc
    54301 attttttcaa cgtctttttc tcgctcttca attaattgct gttttgaact aagtgcttct
    54361 tctttacttt caagtgagtt ctcgcgtttt tctaacgagt catctttacg attcagcgtt
    54421 tgttcgcgtt gaatcaaacg attctcttga gattttaatt ctaacttact ttctctcagc
    54481 tcactttcaa cttcagaacg gtatttctga ttttcttcct tagcttctaa caatgcttct
    54541 ttttttagag tttctgcttc tttttttgca ctatcgatga ttccagcagc tgatgattgt
    54601 gcaccagcta tttctttctc gtgacgtgac tttgcgacca taaaccctaa accaagaccg
    54661 acaattaaac cgatgatagc gaggagaatg ttgaatacca taaaatccac ctccatacta
    54721 tctttttcat ttttatcatc tatacagctt ctatgataaa ttattctaaa ctcgtcaata
    54781 tgcatcttcg catatatgtg tacaaaaaac atgcacaact ttattctaat gtttgtaccc
    54841 cgtagtgtca actttaaata aacaaagaaa cggctttcta cttattcatt aaacgatggt
    54901 ttttaaaata aatgacacta gtttcatata ggtaaacctt taaattgaga aacttttcta
    54961 ttaaattatt ctttgtagat gaacagatat ttttatttta tgtacccact cgtataatta
    55021 aataactcac gatttcttta ttcaataaaa aaacggcagg tcaaggagag tacctactct
    55081 tcagaccagc cgtttttgtt tatcataatt tttattcttc tactaaaggc aattcttctt
    55141 gtcctttttc atcttctggg acagcgactt cttcaccaat accataagct gctctaacta
    55201 gagcagaaac ttctgccatc atttcaggat gattagccat atagatttta gcgttttccc
    55261 gtccttgacc aatccgatct tctttataag aataccaagc accgctttta tcaacaatgt
    55321 ctttttctac tgccatgtct agaagttctc cttcttgtga gatccctaaa ccatacatga
    55381 catctacttc agcgattttg aaaggaggtg ctactttgtt ttttacgact ttgatctttg
    55441 tacggttacc aacaatatct gtaccttgtt tcaattgttc tgcacgacgt acttccaaac
    55501 ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt gatttctgga ttcgcaaaca
    55561 tcacgcctac tttttcacgg atttggttga tgaaaatagc gattgttttt gttttgttga
    55621 tcgaaccaga gagtttacgc aatgcttgag acatcaaacg tgcttgtaac ccgacatgtg
    55681 agtcacccat ttcgccgtcg atttctgctc gtggaactaa agcagcaact gaatcgacta
    55741 ctacgatatc tacagcccca cttgatacta aagcatcagc gatctctaga ccttgttctc
    55801 ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac acctaatttt tgtgcatatt
    55861 gcggatctaa cgcatgctca gcatcaatga aagcggccgt tccgccattt ttttgtactt
    55921 ctgcaatagc gtgtagtgca actgttgttt tacctgaact ttcaggtcca tatacttcga
    55981 tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac atctaacgca agagagccac
    56041 ttggaattgt agagatttgt tggtcgattt tttcgcccaa tttcataata gagcctttac
    56101 catagctctt ttcaattttt ttcagtgcag catctaaggc tgctttacga tcatctgcca
    56161 atacgataat cctccttata tttacaaatc agagcaacat ttcattatcc ttatcatatc
    56221 ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat tcgcatttat cattttctta
    56281 aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc attatatctg atagcagcac
    56341 gatctctggc aaagtgatat ttttccgaaa ccacgccgtc tttagatgaa atagcgatcc
    56401 atactgttcc tgcagattga ccttctaacg tgtccggtcc agccactccg gtgaaagcta
    56461 cactgtaatc tgttcttgct atctcacgtg cttgaatggc catctgctcc acacattctt
    56521 tgctgactgt tccatattct gctaatagct ccggatcaat ctccagaaaa ccagcttttg
    56581 tttggagcga gtaggtaacg aatccgcctg gaaatacttc agatacacca gcaatgtcgc
    56641 ctaatgcggc ttggaaggcg ccggctgtca aactttccgc tgctgttaca gtctgcttgt
    56701 tttctttcag tagttccact acgacttttg ctagcgaatt atcatcgccg tatccataaa
    56761 aatattcccc tactcgttct tggatttttt cttctaatgc taaaagagct tgattccctg
    56821 cctgaacatc atttgttttc actgtcagtc gtaatgtcac ttcatttggt ttggcatatg
    56881 gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt tagctcagtg accagtcgcg
    56941 attcaccaat cccataaaag cgcaaaactt tagaaattag tttttcttca gaaggaaaac
    57001 gttcctctag taaaggacgt acttgttcca caaacattgg tttcaactca ttaggcggac
    57061 cgggaagaag gatatacgca tgtgtatctg tttgataaaa agtccctaaa gcaagccctg
    57121 tacgatttgg tagaggaacc ccgccttcga taatctggga ctgttgcaga ttgtttttgg
    57181 tcatttttcg atgggttgtt tcaaaatatg ccaataattt tttgtatcct tccgtatttt
    57241 gtatgagaga cttaccgagg tgagccgcag ttgcttcttt tgtcaggtca tcttctgtcg
    57301 gtcctaatcc gccacataag agtatgagtt cacttcttgt ttcagctaga gcaatcaact
    57361 cttctaaacg ctgctgatta tctcctacaa ctgtttgata ataaacttcg atacctagat
    57421 cagctagctg ttctgacaag aaagtggcat tcgtattcac gacttgtcct agtaaaagtt
    57481 ctgttccgac agctattatt tctgctttca ttacttcccg ctcccttata tagtatacgc
    57541 tgtattttta tattttttta tttaaaaaga gggcaaggag ctgtgacaaa aatcttgtca
    57601 cagctccttg ttccaaataa acagtgttct cctgccaaaa cctcggtcat aagtcacaat
    57661 atacataaaa catgaaaagc tgttttttga aattatccct tgtgactcag agttagacgg
    57721 caggctcaca acctctccac taaacgatac ttacattgat cctttgaaca caccgctgtt
    57781 tttgatgaag taatccacac ctgaatagat agtaaagatc agacaagcat aaagcatgat
    57841 ttgatctact ggaataccga tcaggctgaa tgggatatta ttgataaaca gcaagataat
    57901 agcaaccatt tgtgtagccg tcttgacttt tcccggccaa gctgcagcca tgacttctcc
    57961 atgttcgaca agtagtaaac gcaagcctgt gacggctaat tcacgacaga caatgatcgc
    58021 tactacccaa ccaggggcct ttccttggtc aaccaacatg ataaaagcag tcataactag
    58081 cattttatct gccaacgggt ccgcaaactt gccaaaatta gtgacaaggc ctcgcgcacg
    58141 ggcaattttt ccatctaacc agtctgtgat actagctaaa gcaaaaataa ctgcacctac
    58201 tagctgtgtg acagccagtg tggtgtctcc tacgttaaat tgtccccaat ctaaaggtaa
    58261 acctacaacc aaaatgaaaa tcgggatcat acaaattcta agtacagtta atttatttgg
    58321 taaattcaca ctatcgactc ctttcttccc tattctacgt gactatcagc gaagtttcca
    58381 ccgatattat ttacttttcc aaatgaattt attcaaagga gtatttttat tgaaattgat
    58441 ctttttgaat taacgaagaa ggaccgcgac acagatttgt cacgatcctt cttttttata
    58501 cctacaagta aacagatgcg taaactaatt tatacgatca ttctgcgtat tgaagagtaa
    58561 ggttcacatt ttttggactc tgattgtttt cccctggatt aactggtacg gattctccat
    58621 tcgctttgat cgttgcattg cttgctgcac caatcgtgat ggtcgcattt gttgctgttt
    58681 ccggtaacac ggtactctgt gtttcatttg ctgccagtgt cccttgataa acataggcat
    58741 tgtctactag cacacctaac catacacgat tgacagcagt aaattcaagg gttacaggct
    58801 tggtagcgtc tgtgatattt actgcgatgg cactgccaga atcttctcct gtagctattg
    58861 ccattttctt ttcttcactt gattttgttg ttgattctac tgtagaagac tctttggtct
    58921 gcgtgctttg ctctgaggaa gaggactcct cgactgatcc ttctacttta agcgaagaag
    58981 ctgtgtctcc gattattgga tcagcttgac gatcttgcca agtcatatag cccacgacaa
    59041 cgacaatcgc caaagcaacc aatcctaata aaatgacagg aagacttgtc caaaagcgac
    59101 ttggatgcga ttcttcctga tgcattgctt ttctagaagt acttactgtt tcaggctgcg
    59161 gacgttcagg gaccgatcct gtcaatttgc ttttcccatc aaaaacatcg actaaatggt
    59221 ctccatcttc tcctacagct tcagcgtatt gccgaataaa tgcccgcacg taaaatttac
    59281 caggcaattg gtcaaaatca tcattgtcga ttgcttccaa ataacgtttt tgaatttttg
    59341 taatctgctg taattcatct aaagatattt ttttattcag gcgtgcttgc cgtaattttt
    59401 ctccgatggt ttcaaaagcc actcgttcat cttctccagt ctgtttgatt ctccgaagca
    59461 tctgctgttg caacgaaaga cgttatgttt gggtgctgtg acaaaagtca tgtcacagct
    59521 ccttttttcc gaataaacat tgttctcctg ccaactcctc ggtcacaagt cacaatatcc
    59581 aataaatata agaagctgtt ttttgaactt gttccttgtg actcggagtt aaacggcagg
    59641 ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc ctcggtatta gctcaaaaac
    59701 cggcaaaata taaggagata tttttccgta tgtttctcta atactcaggt caaaacgctg
    59761 atttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagtccaa
    59821 ccaagttaaa aacattaaga agctgttttt acttggctgt tcttattact tgatgcaggg
    59881 cagctttttc acaacctctt ggtacacggt gttccagaag tagcttcttc ggcaataagc
    59941 cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
    60001 gaccacttct gtcacaacct ctttgattac ttcgtttgat tttattttaa tataagttga
    60061 ttaaaagaga gcatgatttg ttttattttc tcactaattt ttccaacaca actaagaata
    60121 ccataaaagc tgattttgga ggaggttcct actacaagtc taaaacgaaa tttaagactt
    60181 ttcctcataa aatactggtt tattttggtc tcatgtaaaa ctcgctgaag gcctcttcac
    60241 ttataaatgc ttccccagct gccagtacgt ctttcatttg gatcgaatcg atgatttcag
    60301 gaagatcaaa taaagttcga tcgccaaata aactttgcgt aaattgattg gcaatatatt
    60361 cgatcgaatt taatgattgg aaatattgtc caagcatttt cttcttcagc aaatcgagat
    60421 ttgtttctga cacttccgga tcatcagcga atccaagaat gatttctttg actttttctg
    60481 ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc aaagtgaaat tcacgatcca
    60541 agctgaattc aaaaccaaag ctgtcatcga taattccttg attgtacatc gctagatagt
    60601 ttcgagaagt attgcctaaa atcatttgga acaacagatt gattgctgtt ttatagcgta
    60661 acagttctgt tccttcttgc ggcaatgtgt ctaatccttt aataccaagt acaaatttat
    60721 ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat ttcttttgtg ttttcaggga
    60781 aataacgtac aatttcttgc tttggaggga aattttttgc ttcttggttt tcccgaataa
    60841 gtttcatcaa tttctcaggc tccatcttac caactacaaa taaaaccata ttgcttggct
    60901 gataaaacgt ccgatagcac gtatacaagt cttgagctgt gattttgtcg atactttcaa
    60961 ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata caagttattt agtatgccaa
    61021 aaaacatccg ccagttaggg tcgtcttcat acatttggat ttcctgaccg atgattcctt
    61081 tttccttgtt tacagtttct tctgtgaagt aaggtgcttg tacaaaatcg atcagagtcg
    61141 tcagattctt ttctacctga tccgtcgtag aaaacagata gctggttttc gtaaaacttg
    61201 tgaaagcatt ggcggaagct ccttgtttcc caaataattg aaagacatca ccatcttctt
    61261 tttcaaacaa cttatgttct aaaaaatggg caattccatc tggaactttc accttttctt
    61321 tttcaccata gggaataaat tcgttatcga tcgaaccata attcgtactg aacaaaccat
    61381 atgtcttgtg atagtcattt ttaggcaaca aatacacggt caaaccgttt ggcagtactt
    61441 catgataaag tgtttcattg atttgctcat attctgtttt attcatttgc atttcctcct
    61501 gctaaaaaga agattgcctg caattcgatt tgctcagcta cttgttgtat ctctttgatc
    61561 gttacgctct ccatacgttt caaccattct tcatcagata attttgtttc cggcagccag
    61621 ctgtccaaaa aagaagcttc gattgccgct tgcggagagt ctagagaaag cagatattgg
    61681 tttctcagca ttgcttttgt ctgagacagt tccaactctg ttatttcacc atttcgcaaa
    61741 ctttctaatt gctcgtgaat cagatgaagt acttgatttc ggttcttttc atcgataccg
    61801 gtttggacac tcatgaatcc tcggaacgta tccacgctac tagaggcata ataagctaga
    61861 ctttctttct ctctgacatt catgaaaagt ttagagtgag gaaaaccgcc aaataaaccg
    61921 ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat acacatttgt ctgataagct
    61981 aggttcagct ttgcttgaac gattggctca cgtacttgtc gttccttcac gatattcact
    62041 tgaggttggg tataaaacag atctggataa actgtttccc gcgactcaaa tggtaattgc
    62101 ccaactgctt cagctgcttt gtccggatca acatcgccga caacaaaaat gtcgatttga
    62161 tcatttgcca tcatttcttg atagtaggac gctagcgaac tagcagtgat cttgtccaaa
    62221 tcttcgacta cgcccaaccc tgggatcttt tgttccgggc tgttttcaaa ataaagttct
    62281 tgcaaggcat aggaagcaaa agtttgttta tcttccttca aactttccaa atatagacgc
    62341 agattgttct tttccaagtc aaacgtcaac tgatcaaact gatgattttt aatatttgga
    62401 taaaataaaa cctcttttaa aaaatctacc gcttgagaaa aaaggtttgg atcattgaca
    62461 tattcaccat tcacaaaact gatccctgcg tttagccaat gtaaatttcc tttttttcta
    62521 actgataatc caaagcttgc gccataaagc tctgcaagtt gcgcacttaa ctttgtctga
    62581 tccgaataat tcaaactatt tgtttccaac atgctgctga gaagtgaacg tttcgtgatg
    62641 acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc ggatcgtttt gtattgtttt
    62701 gttggtaaga catgaagatt cacgccttct gccaattgat acaccatatt tatatgctcc
    62761 ttttcacagt tgattgcccg cttactcttt taatgggtca acctgccttt tttacttatt
    62821 cctctgcttg aaatttataa gttcaggcaa ttcgccgttt tttctaaatg atgttacact
    62881 ttatagtata gcatagatgt tttttatcaa aagaaacaga cggctaaaag cgtatattgt
    62941 ttttttattt tttatttttc gatatactaa agacaaataa aagaagggag ggtcattcat
    63001 gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc ttggatcttg ctgtcggcgt
    63061 tgttattggt agtgcgttta caagcatcgt aaaccaagtg gtgcaaggct tgatcacacc
    63121 actaataggt tggtttgtcg caatgatcac aggtacttct gatttagaag gagcactttc
    63181 aattcttgac tggtcgccga caaaaggcgt cacatttgcg tttggtaacg ttattagtgc
    63241 tatcattaca tttctgatca ctggttttgt cttattctta gttgtcaaag cggcaaaccg
    63301 tgcgaagaat ttacgctcca aagaagagca agtggaagtg gaagaaactc ctactgcaga
    63361 agattatctt agtgacatac gcgatcttct tgccaaacaa gtggcagaag acaatacaca
    63421 tccagtagag caaacaaatc tttccgatac ttctaaataa taaagaatct aaaaaaaaga
    63481 aagccgattt tcagtgtcgg ctttcttttt ttagattctt aacttgctac ttgttccttt
    63541 ttcatgtcga tatgtggaat atcatcttcc aaatacacat ctgagattgc cttgaatcca
    63601 aacgactcat aaaaagcttg taggtattct tgtgcgccga tcacgattgg tttttctgga
    63661 aaatttttct ggatcatgtt aatcgtttct tgaacaatct ttcttcctaa accatcttta
    63721 cggttgtcct gatgaacaag gacacgtcca aaatggatac tctccgcttc ttcatatact
    63781 cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa acgtatgcca agcttctcca
    63841 tcaatgtcat caacttcttg ataaggacac tgttgttcca caacaaaaac tgcgattcgt
    63901 tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt caaatttctt tacctgatat
    63961 tccactaagc aaacgccccc tgctttttta ttcttagcat accgattcgc acacaaaaaa
    64021 gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta aactgcttca gttaaaaatt
    64081 cgatctcaac tgtccgagta agtacatctg aatagctgta agatactcgt tcaaaagaat
    64141 tttcttcagg atccaaatca acaacgaata ctgaaggata ggtttctgtt aaaacgccgc
    64201 ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa catgattggg ctgccgatac
    64261 gaccttctaa atctttcttg attgaagcta aagttgttgg catacagttc acctctacta
    64321 tcaactatac cacatatttt taaaattttc aagtttacca taaaaaaaaa agaaatgcaa
    64381 taaaaataaa taagaagctc attaagattt ttctaaatta ttcctcatta taaaatttca
    64441 agtgtttttt tattttgagt tttactctcc cgtaagcgct cattacttgc ttgtgatcca
    64501 ttgctaaaca ttcagccatg tctacaaaat caacgccttg catataataa tgaaaaattt
    64561 tagcttctat ttttgaaaac tggatttcgc aattttcgat tgcttctttt aataaaagat
    64621 gctgaattgc taaaggttct tgcaatgtga tctctgctaa aaagtctggt ccttctgtct
    64681 ctattttttg gtcgattgag acttcatctt tttgatcacg acgcttcagc gcgttctgct
    64741 tcctcaacag agaatagatt tgattgctta taacgctttt ataataactt ccaaagctaa
    64801 cacctttgct tttttcgtaa gttctcaatg cctgatataa agcgatcctt gcttcttgtt
    64861 cccaatcctc agaaacataa tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg
    64921 gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc accattacgt gcagcgcgca
    64981 ataactcctc agacataaaa taattcctcc ataaattcgt ttatggagga atcttatcat
    65041 caatgattca tcgaactgat tagaacgata tgttatttat tttttctcat taaatcgtcc
    65101 aatttttggg acaatttttt taactgctct tcattccatg gagaattacg tcggaaatca
    65161 ataaaatgca tatctttatt ttcttgggct attgtttttt ccgttttttt tatcgtctta
    65221 tataattcat aagcagaagt tcgtaatgct ccttgggaaa agatcatcca ctgttctgct
    65281 aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat tcagctgacc agcgattctc
    65341 tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc
    65401 ttataatttt gttggatgcc cggaactagt tgggcatcga agacaacgat gacttccatt
    65461 ccttcatatt tcgcataatt tgataaacga tgtaaaagag cttctcttgc atccgccatt
    65521 ttgtcctgct ttttaagctg gacaagttcc ggccacgaac caatcatgtt gtagccgtct
    65581 acaatcaaca gctgtttttt catggtctac tccccctgac gttgggaaaa agcctgatac
    65641 ataagcaaac cagcagcaac actggcattt aagctctgga cgtgcccggt catcgggatc
    65701 gtcagcaatt catccatttc ttttttcaat cctggactca ttcctttgcc ttcattacca
    65761 atgactaaag caattgatcc tttggcattc catttttgga agtttgtgcc ggtcatatct
    65821 gtgccaaata cccaaaatcc tgtttctttg agctgttgca cagcttgtac caaattcgtc
    65881 acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag tctttgttac gataggtgtg
    65941 attccaactg ctcggtgttt tggtatgatc acaccatcga cgccacttgc gtctgctgtc
    66001 cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg
    66061 tcttcttttt tctcttttgt tcgttcaatc agttggtcaa gggataaata ttcataaggt
    66121 gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt
    66181 ttaggaaccc atttgactgg cacagcttgt tcacgtgcga tttctttcag ttcttctact
    66241 ttttctcctc gtgaatcttc ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct
    66301 tctactgcgg catggtgccc aaagacgaaa ttatcttcta atgcttcttc attttgatca
    66361 gaaactgact gatttcgtcc agtttgcttt ttatttgaat atctattttg ttttttgtct
    66421 tcaaatccac gtttcgattg atgtttgttt gttctttctt tacccatttt tttcaccaac
    66481 tttctgaata caccagcgga tcaattcttc catccgctcg gtttgttttg tcaaatgcag
    66541 atagcccatg agcgcttcga accctgttgc gacccgatac gtcgtaacat cagcattttt
    66601 tgcgctcgta tggcttttag catttcttcc tctgcgataa taaagttctt cttcttctgt
    66661 caaaagatgt tcttccagca tttgctgaat caaaaaggct tgtgcattcg cagaaacata
    66721 attcgttgcc gcacgatgca gcttattggg ttttgtttct ccttgatcaa tcaggtggtc
    66781 acgaacatag atttcgtaaa tcgcatctcc aacataagcc aaggctaaac cgttcaattg
    66841 tgtgtaatct ctcatgcttc tcttctccat cgggttcctt gcggtgtatc ttctaataag
    66901 atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt
    66961 cttgcttgat ttcgttcttc gatcaattgt tcaatctctt catctaataa ctcttctgct
    67021 gtaaataaaa taccgaagat cgaaagccat tgcgagaata aagcttctcc ttgtgccaag
    67081 acagcggcag aaactttcgg ctggtctaga taagtgttca gccacttagc aagctcatag
    67141 accactgtga tcccatttgc tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt
    67201 tctaaatttt ctaacaaagc gattttatcc gcatcatctg ccaaattctc tgaggcagtt
    67261 tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct
    67321 tctttcatcg tcgtttcact gtagcggatc ggacgacggt attgtgtggt cgccatgaag
    67381 aaacgcaaga cttgtggatc aacgtttttg atcatttcat gtacagtgat gaaattccct
    67441 agagatttac tcattttttc atcgtcttcg ccaatcgtta catagccatt gtgcatccag
    67501 taattagcga attttttccc tgttttcgct tcactttgtg cgatttcatt ttcatgatga
    67561 ggaaattcta aatcttgccc gccaccatgg atatcgatcg tttctcctaa atgttttgtt
    67621 gccataacgg aacattcaat atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa
    67681 gaaatctcgc caggttttgc ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc
    67741 tgctgttctt cccctgtacg ctgacttgct ccgacttcca gttcatcgat ggattggtca
    67801 cttaatttcc cataattttc aaatttacgg gtacggtaat acacatcacc tgaagattca
    67861 taagcatagc ctttttcaac caacacttga ataaatgcta aaatatctgg catatgatcc
    67921 atgactcttg gatgcagtgt agcaggttcg acattcaacg ctttcgtatc ttcttcaaat
    67981 gctcggatga aacgatcagc aacttctggt gctgtaatac ctaattcgtt tgctgtacgg
    68041 atgattttat cgtctacatc cgtgaaattc gatacgaaat cgactttata gcctcgatat
    68101 tcaaaatagc gtcgaattgt atcgaaagca atggtgctac gagcatttcc gatatggata
    68161 taattataca cagtcggtcc gcagacatac ataccgacat gtcccttttg tatagggatg
    68221 aattcttctt tttttctggt caatgtattg tagattttta tcattctgat ctcctcactt
    68281 tttctccttt gattcgaacg acttttgctg gtactcctac cgctgtagcg tcgtctggaa
    68341 catctttcaa cacaacggca cctgcaccga ttttggcgtt ttttccgatc gttaccggtc
    68401 ctaatatctg cgcattcgca gagagcatgg ctccttgttt aacagttggg tgtcttttac
    68461 ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa taaaatcaca tcgtcctcga
    68521 tttctgcggt ttcgccaatg acgattccca ttccatggtc gatgaacacg ccagttccaa
    68581 tcgttgctcc tggatggatc tcaacaccag ttaggaaacg ccagaattga gcattgatct
    68641 tcgccaataa aaagagccgg tgctgatata aaaaatgaga gaaacgatgc caaaacaagg
    68701 catgaaaacc agggtatgtc aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc
    68761 tctttgctgc atcaatcgct cgggtaaacc aactcatgac tttccactcc tttcgtaaga
    68821 attttatgta ggaaatcatc ttcttataaa gaaaagaagc gccttttaaa taagtttcct
    68881 tatcaaaaga cgctttccgc gtggttccac ttttcttcat aatcaatgat tatctctgac
    68941 agctaacgcc tgttatacgt tcttggctac tttgtttcct ataaaacagt ttttcctgtt
    69001 ttctgtgttt cgccaagacc actcccagag gcatttcggc aaccattcat tgataccttg
    69061 caccacccgg tatctctctt gtaatgatca gctgcttact tttttctgtt catcgtgttt
    69121 agttcagtac ttgatttaaa tgtgctaatg atttttcacg accaagcaat tcgatcgttt
    69181 caggcaattc tggaccatgc atttgtcctg atacagctac acggattggc atgaaaagat
    69241 tttttccttt tacgccagtt tctttttgaa cagctttgat ggcagctttg acagttggag
    69301 catctactac ttccatttgt tctagctgtg ctttgaatgc gtggagaaca gtaggaactg
    69361 tttcaccagc aagtacttct tttgctgctt cattcaatac aggatgttca ttgaaaaata
    69421 gcgtagacag atcaacgatt tctgcagcat agctcatttg aggttgatac aggctaacga
    69481 tcttcttcac ccattcgatt gtcttttcat ctgggttttc tgctacacgt ccatcagcga
    69541 ttagataagg cagacacatg tcagtaaatg catctagatc cattgctttg atgtaatggt
    69601 tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg tgatttactt aggcgttttg
    69661 gatcgaacat tttgatcaat tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc
    69721 agcccaataa tgcaataaag ttgaacattg catctggtag atagcctaat tcgcgatatt
    69781 gttcgataaa ttgcaagatt gattcgtcac gtttgcttag ttttttacct gtttcactgt
    69841 tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca gccaaatgct tcatagatca
    69901 tcagttgttt tggtgtattg gcaatatggt catctccacg taaaacgtga gtgattttca
    69961 tcaaatgatc atcgaccgca acagcaaaat tataagttgg cataccatcg cgtttttgga
    70021 tgacaaagtc gccaccgata ttatcggatt cgaacgaaat agcgcctttc accatatctg
    70081 taaatgcgta ttctgtattg cgaggcacac ggaaacgtac aacagattct agaccttgtg
    70141 cttctttttc tgcttgttct tcaggtgtca agttcgcaca tgttcctgcg taatgaggca
    70201 tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc
    70261 atttgtatgc tcgattgcta gcaagcagct gatcaatcag cggttgatag atttctttac
    70321 gttcagattg acggtaaggg ccgtattctc caggattttc aggagattca tcccaattca
    70381 ttcccaacca agcaaggttt tccaactggc ttttttcgcc atcttcgata ttacgttttt
    70441 ggtcagtatc ctcaatacga ataataaagt ctccatcatt gtggcgggca aacaaataat
    70501 tgaataatgc agttcttgca tttccaatat gcaggtgccc agttggactt ggtgcatagc
    70561 gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac tagactttga ctaacagcaa
    70621 aaattccgtc agttacggct tctcaaatat catttattta aagccactca gcacaaattt
    70681 taccttttct aaggtaaata gtaaagccaa ctggttgaat ttccttacca gttggctgaa
    70741 tttctttttt attttgattg tttagtcttt ttctctgtct cttttttatt gtcgattcct
    70801 cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag cagctgtttg aagggcactt
    70861 gttacaacga cttcgatacg ttcattcatg taatgctgtc catcttctac gacaaccatc
    70921 gtgccgtcat caaggtaggc tactccttgt tggcgttctg tcccggcttt tactactaga
    70981 acattcatcg tttcaccagg gatgacgact ggttttacgg catttgccaa cgcattgata
    71041 ttaagaacag gtacattttg gaattcagag actttattca agttatagtc attggttaca
    71101 atgacaccat ctaaaagctt agccaatttg atcaatttgc tgtctacttc actgatatct
    71161 tcaaagtctc catcgtacat ttcgacagat ataccctctt ctttttgcaa ggcatttagg
    71221 atatctaatc cgcgacgacc acgcacacgt ttcaaactat cccctgagtc cgcgatgtat
    71281 tgtagttcgt aaagaacaaa attagggatc atcaaggttc cttctaagaa tccagtcttt
    71341 gtaatatcat aaatccgacc gtcaatgatc acgcttgtat ccaagatttt atatttatgg
    71401 aaattttctc ctgattttcg ttctaacagt tgactctcaa cttgactagc tgtttcttgc
    71461 tcgatttttt tgcttcgtga accaaaaact ttcttccatt cttcgattcg tgtcgttccc
    71521 attctcaatc ccagatagcc taagatgatc atcagtaaaa tcggcaatac actattgacg
    71581 aatggaattt ccatattgta aagaggggtc gagatcacaa cacctaaagt caatccgatg
    71641 atcgcaccga tcgcaccgaa gagaagataa gtcaagctga cctcacttag tttttgttct
    71701 acttgtttga taatagctga gatatgtttg gccaacagca aagataataa aaagaaaata
    71761 agtgcgccta acaggctgtt ggtaaatgta ttattcagcc atccgtttga ctgttgaccg
    71821 attgcctgcc aagctgaggg taaaaatgaa atacccaagc ttgcgccgac aatgatcatc
    71881 agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt ttcgacaatc atttattagt
    71941 tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta ctccaactat ctcgattcct
    72001 tttggcgctt cccagttacc taagttgttt ttaggtaggt atacttttgt gaagccgagt
    72061 ttttggactt ctttgactcg ttgttcaata tgactgacac gtctgatttc tccagtcagt
    72121 ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt tttctttata gcttgaagca
    72181 atactgacag cgatagctaa atcaatcgct ggttcattta attttacccc acctgcagct
    72241 tttaagtaag catcttgatt ctgaagaagc aacccagctc ttttttccag cactgccatg
    72301 atcagagata cccgattgaa atcaagacct gttgttgttc gtttggcatt tccgaacata
    72361 gtaggtgtga ctaatgcttg gatctctacc aaaattggac gtgtcccttc cattgccaca
    72421 acgatagcag agccagttgc accgtctagg cgttcttcta agaaaatctg tgaaggatta
    72481 gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca
    72541 aatcggtttt ttactgctcg caaaatccga aaactatgat gttgttcacc ttcaaaatat
    72601 aacaccgtat ccaccatatg ttctaacatt cttgggccgg cgatcgagcc ttctttggta
    72661 acatgaccga cgataaaaat ggctatccca tttgttttag cggttttgag tagttctgca
    72721 gtggtttctc ttacttggct gacacttcct gccacacttg tgatgtctgg ctgcgtcatc
    72781 gtttggatgg aatcaatgat aacataatca ggggagatat gttcgatggc acgactgatt
    72841 tcgttcatat ctgtttcagc gtatagataa aattctgtgt tgatacttcc gaggcgttcc
    72901 gcgcgtaatt ttatctgctc tgcgctttct tcgccggata catataagac ttttccgcct
    72961 atggctgcta attgctgaga aacttgtaac agcaaagtgg atttcccgat acctggatcg
    73021 ccaccaatca agaccataga ccctggcacc acacctccgc ctaacacacg gttcagttct
    73081 tctaattttg ttttgatccg aggttctttt ttagggacga cgtctgcgat ttttgttggt
    73141 tttgcttttt ctcctgtcaa acttgtccga gttctgcggt ccgttgtatc ttgttcgatt
    73201 tcttcgacca tcgtattcta ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac
    73261 acatacccgc aattttggca aacaaattgt acttttgatt tttttgccat tgtaccgcct
    73321 ccttttatcc taatcatgag acattaaatc aagcttaagt atctttaacg ttttatttac
    73381 tggaagaacc aaatccgcct tgacgttgag cagtcgtttg atcttgatct gcttttaaaa
    73441 acggcaaaaa gatcccttgg ccgatacgct cgcctttttt gatcactaca tccttgaaac
    73501 caaagttggt gaattggaac atgatatggc cttcatttgc ctcattattg taataatcac
    73561 tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac
    73621 ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc tttgattcca gtaggcacga
    73681 gggttggttt caattgtttt tcattttctg atacatcttt tttcaatcca tctgcgactg
    73741 tttccaaccc ctttttccag cctgctttcc agatacttgg aatcacgacc tcttctgctg
    73801 cttcaaaatc atagccagca gcatgatgtg tagcgcgctg cggtagattg atattttgat
    73861 ctttatattt agaaataact tcaaatcctc tttttctcac cggttt
//
LOCUS       DADQCX010000002        72809 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.002, whole genome shotgun sequence.
ACCESSION   DADQCX010000002 DADQCX010000000
VERSION     DADQCX010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 72809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.002"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(159..1784)
                     /gene="groL"
                     /locus_tag="J8R83_000067"
     CDS             complement(159..1784)
                     /gene="groL"
                     /locus_tag="J8R83_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAZ9573240.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(1835..2119)
                     /locus_tag="J8R83_000068"
     CDS             complement(1835..2119)
                     /locus_tag="J8R83_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAZ9573241.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            2344..3006
                     /locus_tag="J8R83_000069"
     CDS             2344..3006
                     /locus_tag="J8R83_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAZ9573242.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(3082..4374)
                     /locus_tag="J8R83_000070"
     CDS             complement(3082..4374)
                     /locus_tag="J8R83_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9573243.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            4544..5173
                     /locus_tag="J8R83_000071"
     CDS             4544..5173
                     /locus_tag="J8R83_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAZ9573244.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(5276..6085)
                     /locus_tag="J8R83_000072"
     CDS             complement(5276..6085)
                     /locus_tag="J8R83_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9573245.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(6140..7009)
                     /locus_tag="J8R83_000073"
     CDS             complement(6140..7009)
                     /locus_tag="J8R83_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573246.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(7010..8326)
                     /locus_tag="J8R83_000074"
     CDS             complement(7010..8326)
                     /locus_tag="J8R83_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573247.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(8323..10158)
                     /gene="walK"
                     /locus_tag="J8R83_000075"
     CDS             complement(8323..10158)
                     /gene="walK"
                     /locus_tag="J8R83_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAZ9573248.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(10163..10867)
                     /locus_tag="J8R83_000076"
     CDS             complement(10163..10867)
                     /locus_tag="J8R83_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9573249.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(11057..11917)
                     /locus_tag="J8R83_000077"
     CDS             complement(11057..11917)
                     /locus_tag="J8R83_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9573250.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(11904..12473)
                     /locus_tag="J8R83_000078"
     CDS             complement(11904..12473)
                     /locus_tag="J8R83_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAZ9573251.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            12854..12926
                     /locus_tag="J8R83_000079"
     tRNA            12854..12926
                     /locus_tag="J8R83_000079"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12887..12889,aa:Lys,seq:ctt)
     gene            complement(13422..13808)
                     /locus_tag="J8R83_000080"
     CDS             complement(13422..13808)
                     /locus_tag="J8R83_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAZ9573252.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(13805..14326)
                     /locus_tag="J8R83_000081"
     CDS             complement(13805..14326)
                     /locus_tag="J8R83_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAZ9573253.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(14328..15362)
                     /gene="sppA"
                     /locus_tag="J8R83_000082"
     CDS             complement(14328..15362)
                     /gene="sppA"
                     /locus_tag="J8R83_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAZ9573254.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(15395..16810)
                     /locus_tag="J8R83_000083"
     CDS             complement(15395..16810)
                     /locus_tag="J8R83_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAZ9573255.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(16779..18932)
                     /locus_tag="J8R83_000084"
     CDS             complement(16779..18932)
                     /locus_tag="J8R83_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAZ9573256.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            19190..19426
                     /locus_tag="J8R83_000085"
     CDS             19190..19426
                     /locus_tag="J8R83_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAZ9573257.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            19445..19660
                     /locus_tag="J8R83_000086"
     CDS             19445..19660
                     /locus_tag="J8R83_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAZ9573258.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(20363..21115)
                     /locus_tag="J8R83_000087"
     CDS             complement(20363..21115)
                     /locus_tag="J8R83_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9573259.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(21130..22377)
                     /locus_tag="J8R83_000088"
     CDS             complement(21130..22377)
                     /locus_tag="J8R83_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9573260.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(22453..22599)
                     /locus_tag="J8R83_000089"
     CDS             complement(22453..22599)
                     /locus_tag="J8R83_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAZ9573261.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(22703..23014)
                     /locus_tag="J8R83_000090"
     CDS             complement(22703..23014)
                     /locus_tag="J8R83_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9573262.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(23016..23213)
                     /locus_tag="J8R83_000091"
     CDS             complement(23016..23213)
                     /locus_tag="J8R83_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAZ9573263.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(23607..25334)
                     /locus_tag="J8R83_000092"
     CDS             complement(23607..25334)
                     /locus_tag="J8R83_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9573264.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(25327..26520)
                     /locus_tag="J8R83_000093"
     CDS             complement(25327..26520)
                     /locus_tag="J8R83_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9573265.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(26707..27351)
                     /locus_tag="J8R83_000094"
     CDS             complement(26707..27351)
                     /locus_tag="J8R83_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9573266.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKLHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(27445..27579)
                     /locus_tag="J8R83_000095"
     CDS             complement(27445..27579)
                     /locus_tag="J8R83_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAZ9573267.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(27581..29515)
                     /gene="feoB"
                     /locus_tag="J8R83_000096"
     CDS             complement(27581..29515)
                     /gene="feoB"
                     /locus_tag="J8R83_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAZ9573268.1"
                     /translation="MIARDYLVQEQPELIINIIDATNLERNLYLTTQLLDLDIPMIIG
                     LNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAKKRPSIPVP
                     CTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQKEIEQLIQ
                     LTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATNRWLALPIF
                     AFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQELILNGII
                     AGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSFIPMLIATG
                     CGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSWVAPSAYFL
                     GMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKSFVKKAGTI
                     IFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGTVAAITGLV
                     AKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAPCFAAIGAI
                     HREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILLMIGLVYVL
                     FRQPKSKNQFYTILSLEGEE"
     gene            complement(29512..29712)
                     /locus_tag="J8R83_000097"
                     /pseudo
     CDS             complement(29512..29712)
                     /locus_tag="J8R83_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter B"
     gene            complement(29709..30182)
                     /locus_tag="J8R83_000098"
     CDS             complement(29709..30182)
                     /locus_tag="J8R83_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAZ9573269.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            30583..30807
                     /gene="nrdH"
                     /locus_tag="J8R83_000099"
     CDS             30583..30807
                     /gene="nrdH"
                     /locus_tag="J8R83_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAZ9573270.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            30966..33125
                     /gene="nrdE"
                     /locus_tag="J8R83_000100"
     CDS             30966..33125
                     /gene="nrdE"
                     /locus_tag="J8R83_000100"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAZ9573271.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            33175..34140
                     /gene="nrdF"
                     /locus_tag="J8R83_000101"
     CDS             33175..34140
                     /gene="nrdF"
                     /locus_tag="J8R83_000101"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAZ9573272.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(34229..35368)
                     /locus_tag="J8R83_000102"
     CDS             complement(34229..35368)
                     /locus_tag="J8R83_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9573273.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(35677..36390)
                     /locus_tag="J8R83_000103"
     CDS             complement(35677..36390)
                     /locus_tag="J8R83_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAZ9573274.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(36644..37345)
                     /gene="nagB"
                     /locus_tag="J8R83_000104"
     CDS             complement(36644..37345)
                     /gene="nagB"
                     /locus_tag="J8R83_000104"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAZ9573275.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            37579..39111
                     /locus_tag="J8R83_000105"
     CDS             37579..39111
                     /locus_tag="J8R83_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9573276.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(39302..40504)
                     /locus_tag="J8R83_000106"
     CDS             complement(39302..40504)
                     /locus_tag="J8R83_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9573277.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(40586..41275)
                     /locus_tag="J8R83_000107"
     CDS             complement(40586..41275)
                     /locus_tag="J8R83_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAZ9573278.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(41381..41749)
                     /gene="rplL"
                     /locus_tag="J8R83_000108"
     CDS             complement(41381..41749)
                     /gene="rplL"
                     /locus_tag="J8R83_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAZ9573279.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(41802..42305)
                     /locus_tag="J8R83_000109"
     CDS             complement(41802..42305)
                     /locus_tag="J8R83_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAZ9573280.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(42715..43404)
                     /gene="rplA"
                     /locus_tag="J8R83_000110"
     CDS             complement(42715..43404)
                     /gene="rplA"
                     /locus_tag="J8R83_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAZ9573281.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(43508..43930)
                     /gene="rplK"
                     /locus_tag="J8R83_000111"
     CDS             complement(43508..43930)
                     /gene="rplK"
                     /locus_tag="J8R83_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAZ9573282.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            44273..44941
                     /gene="sdaAB"
                     /locus_tag="J8R83_000112"
     CDS             44273..44941
                     /gene="sdaAB"
                     /locus_tag="J8R83_000112"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAZ9573283.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            44954..45826
                     /gene="sdaAA"
                     /locus_tag="J8R83_000113"
     CDS             44954..45826
                     /gene="sdaAA"
                     /locus_tag="J8R83_000113"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAZ9573284.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(45917..46936)
                     /locus_tag="J8R83_000114"
     CDS             complement(45917..46936)
                     /locus_tag="J8R83_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAZ9573285.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(47109..47996)
                     /locus_tag="J8R83_000115"
     CDS             complement(47109..47996)
                     /locus_tag="J8R83_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9573286.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(48073..48618)
                     /gene="nusG"
                     /locus_tag="J8R83_000116"
     CDS             complement(48073..48618)
                     /gene="nusG"
                     /locus_tag="J8R83_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAZ9573287.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(48719..48889)
                     /gene="secE"
                     /locus_tag="J8R83_000117"
     CDS             complement(48719..48889)
                     /gene="secE"
                     /locus_tag="J8R83_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAZ9573288.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(48913..49065)
                     /gene="rpmG"
                     /locus_tag="J8R83_000118"
     CDS             complement(48913..49065)
                     /gene="rpmG"
                     /locus_tag="J8R83_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAZ9573289.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            49227..49871
                     /locus_tag="J8R83_000119"
     CDS             49227..49871
                     /locus_tag="J8R83_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9573290.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(49927..50430)
                     /locus_tag="J8R83_000120"
     CDS             complement(49927..50430)
                     /locus_tag="J8R83_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAZ9573291.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(50443..50489)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            51027..51992
                     /locus_tag="J8R83_000121"
     CDS             51027..51992
                     /locus_tag="J8R83_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAZ9573292.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(52091..53263)
                     /locus_tag="J8R83_000122"
     CDS             complement(52091..53263)
                     /locus_tag="J8R83_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573293.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(53250..54395)
                     /locus_tag="J8R83_000123"
     CDS             complement(53250..54395)
                     /locus_tag="J8R83_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573294.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(54409..55333)
                     /locus_tag="J8R83_000124"
                     /pseudo
     CDS             complement(54409..55333)
                     /locus_tag="J8R83_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            55450..56529
                     /locus_tag="J8R83_000125"
     CDS             55450..56529
                     /locus_tag="J8R83_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9573295.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            56561..57154
                     /locus_tag="J8R83_000126"
     CDS             56561..57154
                     /locus_tag="J8R83_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9573296.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(57264..57491)
                     /locus_tag="J8R83_000127"
     CDS             complement(57264..57491)
                     /locus_tag="J8R83_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9573297.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(57594..60182)
                     /locus_tag="J8R83_000128"
     CDS             complement(57594..60182)
                     /locus_tag="J8R83_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAZ9573298.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(60202..60861)
                     /locus_tag="J8R83_000129"
     CDS             complement(60202..60861)
                     /locus_tag="J8R83_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9573299.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(60910..61413)
                     /gene="trmL"
                     /locus_tag="J8R83_000130"
     CDS             complement(60910..61413)
                     /gene="trmL"
                     /locus_tag="J8R83_000130"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAZ9573300.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(61634..62500)
                     /locus_tag="J8R83_000131"
     CDS             complement(61634..62500)
                     /locus_tag="J8R83_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9573301.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            62609..63250
                     /locus_tag="J8R83_000132"
     CDS             62609..63250
                     /locus_tag="J8R83_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAZ9573302.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(63312..64673)
                     /gene="mgtE"
                     /locus_tag="J8R83_000133"
     CDS             complement(63312..64673)
                     /gene="mgtE"
                     /locus_tag="J8R83_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAZ9573303.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(64691..65590)
                     /locus_tag="J8R83_000134"
     CDS             complement(64691..65590)
                     /locus_tag="J8R83_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAZ9573304.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(65592..66389)
                     /locus_tag="J8R83_000135"
     CDS             complement(65592..66389)
                     /locus_tag="J8R83_000135"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAZ9573305.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(66367..67071)
                     /locus_tag="J8R83_000136"
     CDS             complement(66367..67071)
                     /locus_tag="J8R83_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAZ9573306.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            67202..67778
                     /locus_tag="J8R83_000137"
                     /pseudo
     CDS             67202..67778
                     /locus_tag="J8R83_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
     gene            67896..68573
                     /locus_tag="J8R83_000138"
     CDS             67896..68573
                     /locus_tag="J8R83_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAZ9573307.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(68652..70460)
                     /gene="pepF"
                     /locus_tag="J8R83_000139"
     CDS             complement(68652..70460)
                     /gene="pepF"
                     /locus_tag="J8R83_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAZ9573308.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(70636..71634)
                     /locus_tag="J8R83_000140"
     CDS             complement(70636..71634)
                     /locus_tag="J8R83_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAZ9573309.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(71860..72513)
                     /locus_tag="J8R83_000141"
     CDS             complement(71860..72513)
                     /locus_tag="J8R83_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAZ9573310.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        21810 a        15023 c        12381 g        23595 t
ORIGIN      
        1 agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc aatttccgtg
       61 aatttcttct tatttcttgg agttaaacgc ttctgttcca gcctcttttt atctgtcttt
      121 cactaatgat cagttgtaga taagcaagtt gctttttctt acatcatacc gcccatcatt
      181 gatggatcca ttgcaggagc tgctggcgct gctggttctg gtttatctgc aacgactgct
      241 tctgtcgtta ataacaaggc agaaacggaa gcggcatttt gcaaggcaga acgtgttact
      301 ttagttgggt ctacgatacc tgcttcaacc atgtttaccc attctccagt agcagcattg
      361 aaaccagtgc ctagttccac gttcttcaat ttatcaacaa tcactgatcc ttcataacca
      421 gcgttttcag cgatttgacg aattggttct tctaaagcac gaacaacgat cttgatacct
      481 gttgccacgt ctccttctgc ttctacagca gaaactttgc tgataacgtt cactagagct
      541 gtaccaccac ctgagaccat tccttcttct actgcggcac gtgtagcatt caatgcatct
      601 tcaatgcgta attttaattc tttcaattct gtttcagtag ctgcaccaac tttaacaaca
      661 gctacaccac ctgctaattt agctaagcgt tcttgtaatt tttcgcggtc aaaatcagaa
      721 gttgtttcag caatttggtt tttgatcaat tgcacacgag cttcgattgc ttctttttct
      781 ccagaacctt ctacgatcgt tgtattgtct ttatctacaa caactttaga agcatttcct
      841 aagttttcga ttgttgcatc tttcaattct aaacctagat cgtcagtaat tactgtacca
      901 cctgtcaaaa tagcgatatc ttcaagcatt gctttacgac gatcgccgaa accaggagct
      961 tttacagcta ctacgttgaa tgttccacgg attttgttca atacaagagt tggcaatgct
     1021 tcaccatcta catcgtcagc aataatcaac aatggacgtg attgttgcaa gatttgttct
     1081 aacaatggca gaatatcttg gatgttagag atttttttgt ctgtgatcaa gatatatggg
     1141 ttttctagaa cagcttccat tttgtcgtta tctgttacca tatattgtga taagtaacca
     1201 cgatcaaact gcataccttc tacaacatct agttctgttt cgatcccttt tgattcttcg
     1261 attgtgatga caccgtcgtt tccaactttt tccattgcat cagcaatcaa atgtccaact
     1321 ttatcagaac ccgaagaaac agctgctact tgtgcaatgg cttcttttga atcaacaaca
     1381 gttgagatat tatgcaattc ttcgactgct gcttttgttg ccaattcgat cccgcgacga
     1441 atgcctagag gattagcacc tgcagttacg ttttttaaac cttcgcgaac gattgcttgt
     1501 gtcagaacag ttgctgtcgt tgtaccgtct cctgcaatat catttgtttt tgatgctact
     1561 tctgatacaa gttttgcacc catgttttca aaatgatctt ctaattcgat ttcttttgcg
     1621 atcgtcacac catcatttgt gatcaatgga gagccgtaag atttttctag tacgacattt
     1681 cggcctttag gtcctaatgt tactttcact gtatctgcta atttatctac cccgcgtaac
     1741 atagctgcgc gtgcgtcttc tgcaaatttc aattcttttg ccatgattga ttcacctcat
     1801 tgattatttt tgattatttt tttatcttcc aaatttactc aacaatcgcc atgatatctt
     1861 ttcctgcgac gatcagatat tcttttcctt cgtattttac ttctgtaccg gcgtattttt
     1921 cgaacataac ttggtcgcct gcttttacag cggcaggaac tttttcaccg ttttctaaca
     1981 aacggccttc accgactgca acaactgtcc cagtttgggg tttctcttta gcagcagaag
     2041 ctaaaacgat tcctccgaca gttttttctt cttcttttgc gacttcgata atgacgcgat
     2101 cacctaatgg ttttaacacg ataaatccct ccgataactc tttttttaat ctgttagcac
     2161 tcttaacctt cgagtgctaa cctacatttt taataatact cattctccct cttttttgca
     2221 agcttttaaa tcaaagaaaa gaaattttat tctgacagct gcttattgaa attatgatat
     2281 aattgaaatc aatcgatata agcttgcctt gcatgcttgt tatcccttaa aaggaggaat
     2341 tacatgtctt taaaaaaata tagcttcctc agcatttttt gctatggtct aatttttatc
     2401 tcacccttga tcctagcttc gataggactt gtaaaatcta cgtctgaatt gatcacagca
     2461 actgcagtca tgtatatact aggcgccgtt gtcctagcta ttttttattt taagcaacgt
     2521 gaacccttag cgatcgaatc agcggtaaaa aaagcttctg ctccaaagat tgttatttat
     2581 ggattggttg gaatctttgt cgcattgatt ctgcaaagca tcgctgtcat gttagaatct
     2641 gtattgtttg gcaaagcaac cccttccgag aatacacaaa atatcatcca gatgatcatg
     2701 gaagcacccg cttttatttt ggcgacaact gttgctggac ccatcatgga agagttcgta
     2761 ttccgccgca gtatactggg gatcatcagt cgatattcaa atttttgggt cggagcagtg
     2821 atcagctctt tgctgtttgc gtttgctcat aatgatggtc atctgctaat ctactttttc
     2881 ctaggtttct tcttcagcct agagtacaaa gcaactggtc ggatctggac atcgatgatc
     2941 acacacgtag gaatgaacac attagttgtt cttgttcaat tagctgtcca aaaagggcta
     3001 gtataaacat gactataaat actcctgtca tcctagattg gtgattttcc caatctaaag
     3061 cgacaggagt atttttgttt tttagtcgtt catcttttct gctgctccat cattttttgt
     3121 ctgtctttcc tttttgcagt ttgcagaatc tatttttttc aaaaatggga aataaatgaa
     3181 aaaactaatt gacaacacga taccttgtaa aatcgctgca ggcactccgc ctactaagaa
     3241 acccgagagg atcggcggtg ttgtccaagg gacttggact gctgtaaata aaggaacgaa
     3301 tccaaaatat aaagcggaat aggtaatcaa tcctgaaacg accggtgcga aaataaaagg
     3361 aacagccatc atcgggttca tcacgatcgg tgtggaaaaa ataattgatt cattgatgtt
     3421 gaaaaaggct ggtaaaagag caagatttcc taattctctg tatttcttcg atttcgcaaa
     3481 aaccgtcata aaaaatacag cccctaacgt caatccagca cccgtaaccg tcatgaactg
     3541 atcgagaaat tgctgagtaa cgatatgtcc gccatttgcc accgtcaact cttgtcctga
     3601 ggctaagatt tctgcatttg ctaatgaatt cgcttgcaag acgggactaa ccaacccatt
     3661 gaccatcgca gatccatgaa gaccaaataa ccataaaaac ggaacaaaaa aacctaataa
     3721 aagcacacca aacaacgtgt ctatgaacga ttgaatggga agctggacat atgtccatac
     3781 tccttgaaca acagtcattc tgaacaaatg ttgaaaaacc gctgaaccga taagcgtaaa
     3841 agtgactata acaatgattg gaatcaatga agtaaaagac tgccaaacat tttcaggtat
     3901 cttctctctt tgcttccacc ctttcgcaag tcttactaaa cgtgcatagc cccatccgat
     3961 gatgagccca gttgtaactg ctcctagtat cccttcagca cctgtccaga cagtatctat
     4021 ctgagtattt agtggctgaa taagcagtag ataagcagac aaggctgtta tgccgactgg
     4081 taagcgatcg atgtcttctt cttttgcata agcgtatgca atggcaaaaa cgatccaaaa
     4141 ggctatcaca tcaaatgtag cctggtatac ttgtgtaaaa tacatagaaa atcctgtttt
     4201 gtctatccac tgagcgatgt aatccacagg aaaatgagca aataagaaaa acagcgagcc
     4261 aacaataatt attgggatcg tgtaagtcat tccattacgc aaagcagtta agggtctaag
     4321 attcacaaca gatgttatca ttggtaaaaa ggcacgatct aaccactctt tcatttctta
     4381 tctccttcaa cttctatttt tatcaatcag ttttcttaat ttaactatac ccaatgatca
     4441 cgaaccatga aaggaatgcg cactgagctt ttcaaaaatc ggattctttg acgaatattc
     4501 agcaactgct tacaatggac aggaataaaa aaggaggttt tttatgaaaa ttgcactcat
     4561 tggagctact ggccatgcag gttcatttat tttagacgaa gcattgtcca gagatttaga
     4621 cgtgacggca atcgtgcgtc atccagaaaa attgccatca gatgttccgt ttatacaaaa
     4681 ggatttattt gagttgacaa ctactgatct tgcatctttt gatgttgtcg ttgatgcttt
     4741 caacgctccc aaaggaaaag aagaaatgca tcaaacttct ttgtcccatt tgattgagat
     4801 gcttgaagga accgatacac gcttaattgt cgttgggggt gcctcttcgt tattcttaga
     4861 tacagaaaag acgactcgta tgattgacca agtacctaaa aatgcaccct tctatccaac
     4921 agctttcaat atgtacgaag gattgttaaa attgaaacaa tctaaaaatc tacattggac
     4981 ttatatcagt ccagcttctt tatttgatcc acatggcaaa cgtacaggta cttatttgtt
     5041 aagtgatgat tatttacaaa gaaacgctgc tagcgacagt acgatcagca tggcagatta
     5101 cgcgattgca ttagtagatg agatactgga tgagaaacat gaaaagcagc acatcagtgt
     5161 agtcagtcga taatacggtt atttttttaa tatgctaaaa aaataaaaat agaagataaa
     5221 accaaccctg attgatttta tcttctgctt tttatatttt tattgattga actgtttaaa
     5281 tcgaaaatag ctcagttgct tcatctggat ctgtatcata gatttcaaaa tcatgtccaa
     5341 cgccaaaatc tttttctttc aaaacatttt ccattgttaa atgagcaagt tctttcatat
     5401 tgttttcctt gctaagatgg ccaagataga ttcgtttggt ccgattaccg atcacatcag
     5461 tcatgacaag tgcaccgtct tcgttggaaa gatgtcctct atctcctaaa atacgctgtt
     5521 ttaaattcca cggataaggt cccatgcgta acatctcaag atcatgatta ctttccatca
     5581 aataaccatc ggcattttca atgacacctc gcatataatc actgcaatat ccggtgtccg
     5641 tcaacatgac gaatgaccga ttttctttat ggaaacgata aaattgcgga gccgctgcgt
     5701 catgggagac gccgaaactc tcaatatcga tatcgccgaa tgttctgact ttccccatct
     5761 caaatagatg tttttgttcc actggtacat ttccaatcag tggttccatc gcttcccaag
     5821 tctgctgatt ggcaaaaaca tccaaatgat acttacgagc caagacaccc acgccatgta
     5881 tatgatctcg atgttcatgc gtcacaagta ttccatctaa ttggtccggt gtccgatcaa
     5941 tttgagccat caaggaagtg atttttttac cgctaagtcc tgcatcgacc aaaagccgtt
     6001 ttttttcact ttcgatataa agtgaattac ccgaacttcc acttgctagg atactgattt
     6061 taaaagctgg tttttcttca gccatttgac tcctacttcc cttcttactt tgtaaacttt
     6121 tttcattata ctcgcttttt tattgatctt ccacttttgg tacagtattg tttgtcacga
     6181 tcgtattgct gaaagcgttg acgctctcaa tttggaccac tttatcgctt gtttcgatcg
     6241 ctacatgcca aacaggaaca tacacatttt tttcccggac tttcagaata caggaataag
     6301 ctagctgacg ccataaaatt tttgatcctc ttggtatttt gttattgatg tacaatgtat
     6361 tgattgcttc ctcttccgta tacagttccg tcttttcgcg cagctgctcg atatcagata
     6421 aatgcgtctg catgtatttc gtgatgctat aatcattatc gtttttttct aaagaaagaa
     6481 cgatttttgc tgtatcatca ttgaatggga tgccttcata ctcttggctt gcttggattt
     6541 ctagtggttc ttcttctaaa tgagaaaagt ttttcgtgta cacataatca ttaccgaata
     6601 aaatattgtc tttgttagat aaaaaatctt ccaaggaact actaatttta tctggatcga
     6661 tcacgttctt ttcagcatct gaactggata aagatttcgt caaaacatca ccgtctaaaa
     6721 acacaccact tgccagcaag ccgcttttac cagccttgcg ataattcgct aatgaagtgc
     6781 taagattggt ctgctccgcg ctaagataat agccttgctt gttctcagac gaaatcttcc
     6841 ccgtgtaagt gatatcgtcg ctagccagac gttgttggat tgattcagtc tgattagagc
     6901 gaatgacatt gttttcttgg tataccgcgt catgataact gctgaataaa aacacattca
     6961 accctaaaaa agcgacgaaa aatatccatt cgattttttt gaaatccaat taattcgcct
     7021 ccaatccagg taatttttcc agaaggtcgt tagctgaata ccagttatct ttatatttca
     7081 cataccattc aggtaagaga tcaacgacac gattcgtttc tttgacattt tgccatgtat
     7141 agccaacgat cactgaacca atcttgttgc tatctgctcc cttagctttt aactgctgga
     7201 tgatttcatt cgtacttgca agttctactt cttcgtctga aggtatcggc acttgaatcg
     7261 tattcaaact ggtttggata ttcacttgca cagaaccatt cgtttcaccg ccaacttcca
     7321 caccaatctg tcctctgctg tctgtcccaa aaaccgggaa gccttccacg aatatccgat
     7381 aatcgatcgt attgtcactg cggtcaaaat atctgaggtt ccctaaagaa ctgcctaatt
     7441 tgctaatata ggggaaactt tcagaaaata cactagcatt ttcttttttc tctggcagct
     7501 ctccacgaaa atcaactact tgcgtttccg aatggataga cattgtttca ttcccaccgt
     7561 aaaaaatcaa ttcattgctt tcatcattat ttttcacgct atctggtttc tggaaaaaag
     7621 catttctaaa aagtgtatag ggttgctgtg acaggatata actatacttc ttcagtttga
     7681 tcgaatgttt cgtagcatat tgcgtgtcga tcgtcgatgg ttctgttgtc atttctgtcc
     7741 attttgtgtc ttttgctgtt aattctttat tgatatctgt ccaattcaac gaaatatttg
     7801 cttcatatac gagatggttc gaataattca aaaatcggat ttttttattt ccttgatcga
     7861 attgtattct agtaaaatac atattttcgc tttcttttgc caagttcgac acatctaaat
     7921 ctaaatcaaa tgcttccttg tattctctta gcaaaaaagg cgcattatag gccaactcaa
     7981 aaccagagtt cagatttttc acctgttcaa actgtgattt gtctcctgaa actacttcag
     8041 aaagctttcc aaatcttgct ttatcgatga tcaattgcaa tcggtacacg agattttcac
     8101 tgttggtttc ttggatcatt cccgaatggt gccatgtaac atgaagcgga agaaagactt
     8161 cggaagtttt tcgattgctt tgagactcga tcatttgagt gtttgtctca tctacgttga
     8221 ttgaactttt tcctgctggg ctcagccaga ttgcataaga gaagtatatg cttaacgcaa
     8281 ccatcaaaat gagtcctata cgaacgactt tttcagagat tctcattccc accattcctc
     8341 ctcataaggt tcatatggca gcgagatata aaaagtcgac ccttttcctt ccttgctctc
     8401 tgcccaaata gcgcctcgat gcgccttaat cacttctcta gaaatagcta atccaagtcc
     8461 tgtcccacct tgtgctcttg cacgtgcttt atctactcga tagaaccgct cgaacactcg
     8521 gttcagatct tttttaggaa tccccaatcc ttgatcggtg atacttaaaa tcacgttatt
     8581 atgcgtttct aataagcgac aagtaatcgt tcccccatct ggtgaatact tgatcgcgtt
     8641 attcatgata ttatcgacta cttggatgat tttatctgta tctacttcga cccaaagatc
     8701 tctttgcgta aattcacgac ggatcttata atttttttcc tgatttccca ccatcatatc
     8761 aaaccggtca agaacaaaat tcactaactc gttgaaattg acatattcta attgaagctg
     8821 ggtattacct gtatccatgc gagatagatt taagaggtca ttgatcattc gaatcattcg
     8881 gtctgtttca tctagcgtta ccttcaaaaa atttggtgct acttcctcgt ctttccacgc
     8941 accttcgctc aatgcttcga tataactacg catacttgtc aacggtgtac gaagttcatg
     9001 ggaaacatta gagacgaatt cacgacgttc ccgttctgtt ttttcttgtt ctgtcacatc
     9061 atgcaagaca gctactaatc cgctgataaa acctgattcg cgacggatca tagaaaagtc
     9121 tactcgcaag atcatctgat cactttccaa tgtactggtt gaacggtcaa gtaccatttc
     9181 gtttggatct tctaataatt tccgcaacgt atattcttct tcgatatcta aaagtgtcaa
     9241 aatcgattgt ccgattgctt cctcgttttt gatatctagc aaggaaacag ccatatcatt
     9301 gatcgtaatg actttacccc tgcgatctgt cgcaatgacg ccgtctgtca tatgggatag
     9361 cacgctatcc aaacgattgc gttcagcttc cattgtatct tgagcttctt caatacgttc
     9421 agctaactga ttgaaggtat cagccagctg tccaagttca tcttgtccat gcactttgac
     9481 tttccgactg tagtctcctc tagcgattcg aatggcttgt tctctcattt caccgatcgg
     9541 ctgtgtaatc gaacgagcaa ctaaaacaga tacgatcatt gaaataaatg ccgcaattag
     9601 tgaggcagta aagaaaatga ctgctgtgtt attgatttcc gaatattttt gttcgatatt
     9661 acttttgacg taaagagccc cgataacggc atcgccggtc ggggacagga tcggttgaac
     9721 attgatattc acccgtttat cgtcgttatc taaagcaaca taacgtttag tcgtgaaatc
     9781 attgatatca acataatcat ttttctttcc cacagcgctt tgttcattga catcggttgt
     9841 tcctcggatg atcccttttt cgtcaacgac ccgtatttcg atgatatcgc tagtcgcact
     9901 gttttcaata aatcttttga tattcgcatt tacctcttca tcatctgcat tatcttttcg
     9961 attcaattcc gggctgattg ttgttgctaa tgattccacc gtttgattca tatctttaat
    10021 aaatgtattg atcgtggaac gttctaaacc acgtataaag taggcaccaa taatttcgat
    10081 cgagatcaat aaaatcagaa taaaggtaat agcgatctta aaattgactg atcgaaaaaa
    10141 gcggactttt cttttcatcc aattactcct gttctgggtt acgcaaatag taaccgacac
    10201 cacgacgtgt cactaaataa tttggatggc ttggattatc ttcgatcttt tcacgcaaac
    10261 gacgtacagt tacatccact gttcgtacat ctccaaaata atcataaccc caaaccgttt
    10321 gtaataaatg ttctcttgtc atcacttgtc caaggtgctt cgccaagtaa aagagtagtt
    10381 cgaattcacg atgtgttaac tcgattgttt ctcctcgttt cgtcaccatg taagcttctg
    10441 gatggatcgt caaatcacca atcgtcaatt ccgcaggtgc tgcctcttct ggttccttcg
    10501 cagccgtggc accgcgacga agatttgctt tgacacgtgc aactaattct cggttggaaa
    10561 atggcttggt cacgtaatca tcggcgccta actctaagcc taggacttta tcaatttcag
    10621 aatctttggc tgttaccata atgatcggca tatcataagt tttgcgtacc tcacgagcaa
    10681 cttctaagcc gtccatttta ggtagcatca aatcaagtaa aatcaaatca ggttctacct
    10741 cagcaacttt ttccaaggct tcttccccat catatgcagt ataaacgtca tagccttctt
    10801 tggctaaatt gaatttgacg atatccgaaa tcggcttctc atcatcgaca actaaaactt
    10861 ttttcataaa gagccacctc ttatatatta ttgtcatacc ttctcattat accgtatttc
    10921 tgcttttgtt tcatctttgc ctataaaaca aaagagaaaa ttaaaatgaa agtgcaaaat
    10981 actttattat tttttgttct aacttcaata aaaaaggaaa acactgattt tcacctcagt
    11041 gtttcctttt tttgatttat ccttctaaaa cttgtacacc gacacccaat aatcccggac
    11101 cagtgtggac tactaatgcc ggagaaatct ggccaaagta gatttggttt gcttgtggga
    11161 actctctttt aagtctcgct tccatttcaa ttgcttcttc tttcgcatcc ccatgggcaa
    11221 cagctaagtt gaagaccttt gcattaccga ttttttcttt gacgtaagca accgttttat
    11281 ccaaactttt tttacgtccc ctagcttttc ctactgtgta ataaatccct tcttcattac
    11341 atgagatgat tgggttaagc tttaaagcgg ttcctacaat agaagcaact aaaccgatcc
    11401 gtccaccttt ttgaagatat tccaatgtcg caacattaaa gaaaactttt gttctttcga
    11461 ctaactcatt cagattactg atcagttgat cccattctac tccttcttcc agccattttg
    11521 ctgcttggat cgcagaaaaa cctgcaccaa taccaatatt tttcgtatct agtacatatg
    11581 cttccaattc ttcttgctgt tgtgcaatta aacgaaccac attatatgtc ccgctcaatc
    11641 cactggaaat tgttaccgca agtacctttt cataaccgtc ttttttgatt tgctcaaaga
    11701 tttctgtgat cgactcacca tccggcaaag atgtaccagg gatttcctct ggcaaacgtt
    11761 gatagatctc ttcaggggta atgtcaattt tatctgtata tacctgatct ttataaataa
    11821 ttttcaatgg gatcatatac atctcgtatt tttttatcaa ttcttctgga acatccgtac
    11881 ctgaatctac taaaattgcg attttattgt ttttcatttg ttttctcctc ttttaaatat
    11941 tcggtttcta gaacaatcgt tttttccgca agaagtttca ttgcaaacga taaagttgcc
    12001 gctcttacag caatatattc tacaggggtt gcctggtcga atttttgcgg atgagattta
    12061 ccttgtgcta attggctgac catccacaca gctgcttctt gttcatcgca aaatagatta
    12121 taggcttcac gaattcctac tgtttttcct tggaacaata tcccttcttt gatttcagga
    12181 atagtcaata cttgtttcaa cgtagtgatt gcaagtaaaa atgctacgtg ttctttgtta
    12241 tatctttttt taactggtgc tggtatcaaa cctagtttaa cgtaattgtt taccatagaa
    12301 gaggtaagca atggatgctt ttctccttgt atcacaggtg aaagataacg atcaactaac
    12361 gttctgactt ggtccatata aagttctaag tcagggagtt cttcccagtg aggcagacgg
    12421 aatgtttcta gttccttccc ccactccatt aattgctgac gcattttttc catcataacc
    12481 gctccttttt tcatttcata aacatgatat cagacttatg ataaacattc aatctagttg
    12541 ctttaactag gtgatttgat tagcgggatt ccatgaaaac aaaaaacaag aaggctaagc
    12601 cttcttgtct tttatcgtta agaacaggag acccgccggg gagacggcgg gaaaggagta
    12661 aaaaatgaaa aaagtgttag ggtttgttct cttgcaagaa ctttgtttgt tggtatgctt
    12721 atataatagc gagcaaatgt gaataatcta tgaatgattt cctataagga agtaaagatt
    12781 tttctgattt tctttaaatg tagtcttgca ttttaaaatt cttagtgcta ctattattaa
    12841 gtactttttg tacgggccgt tagctcagtt ggtagagcag ctgactctta atcagcgggt
    12901 cgcgggttcg agcccctcac ggcccattgg gtgccaaacc cacggaacag gtaaatgttg
    12961 gtgcgaaagc atttcgaaaa catttacgct gttctttttt tatttttcaa aataactagg
    13021 gctttttatt tttaactcaa agtccactgt agccctttgg actttgagtt aaaaaagaag
    13081 cataattatg aacagtaaag tttctaatat aacaataatt cgagaagctt tgcaaaatca
    13141 tgctgccaat gaactctcta aacatatagg attaaatcta agtactataa aaggttaaaa
    13201 agtgaagaat atttaataga aaaactaaat ttacttgctg ctttcccctt ttccattaat
    13261 acaacaatca gagagtgtct ttttttcgaa aaaattagaa taaataaaag acacgtagtt
    13321 tttttatcta catgtcttcc atcgactaca agttatcatt tctcaaaacg tatttagctt
    13381 ttaattgatt aatcgtttca cgttgtctac acattgccta attaagattt tcttattaga
    13441 agcatcaatc ccgcaataat acctaaaact ccaggaatta cccacaataa tgttaaaaga
    13501 aaaaatggaa taatagataa aatgagtaaa ctaataccat agaccactgt tttttgattt
    13561 tttcttacta aaaaacctat tatgaaaatc attatcgaaa aaactagggt aattcctcca
    13621 aataaaacaa cattcccgct tagattgact aacatatcta tatccttact ggttagttct
    13681 gtagtattta aagtagttga atcaatagaa gatagaaaca taccacccat caatgctaaa
    13741 agactacata aaatccctgt tattccacta attaaaatca aaataaactc tgtttttctc
    13801 ttattcattt aattctctcc agattaagtg ttttagaatt agaaattttt tgaccatagt
    13861 taatagcttc taatgaacga ataacaacca ctgacgtgtt agaaaaataa tccccaatat
    13921 gttgtttctt gggcgtgaaa gcagccacca aatacccaat ttgaaataca aaatttttta
    13981 atataaacct acatatacac tcacgaataa agatagtttg ccaacttagc tctttttcct
    14041 caaagctcac tactcttatc ccaaaaatca ttttcccaat tgtttgtcct gaattcagct
    14101 tagtcaaaag tacaaaatag gttaaataaa tagctaatga cgctatacca taaaaagtaa
    14161 taatggattt gtcagattcc agtcccatga ttttgtaaaa gagacctata gtagcatggg
    14221 tgatgatgct aatacaaatt aaatcaataa gaaaagcaaa aaatcgtaac caaaatcccg
    14281 caaatacata attaggcaaa gtttcaatgc cactcttctt attcatttta tagccctcca
    14341 tagtaataca ttggttttgg agtatcagaa aatccaagtt tttcaaaaac tgaaattaca
    14401 cgatctgatg tagttgcctt tagcccttgc cattcagcaa tcttattacc taaccaagaa
    14461 gaagcaaagc cagttgtgtc atttttatat tctataaccg tcgcatcagt taatttcttc
    14521 tcttttttta gggaatctaa tgcatcttca gagtaaccaa tttgatccac caacccattt
    14581 tctactgctt ggttaccatc ataaattctt ccatccgcaa gttctttcac tgcattagta
    14641 tccatatttc ttccttttgc tacaacattg acaaaacgat cataagcact catcacaaat
    14701 tcctgtataa ctttattctc ttcctctgaa ggtttgtgtt gaggtgacat catatctttt
    14761 aatgcaccac ttttatacgt cgcatcagtt acgccaagtt tttctaataa gccagaataa
    14821 tttaaaccag aaataatgac accaattgat ccagttgttg tttcttccgt agcaaatatt
    14881 ttatctgaac cagcagaaat gtagtaccct ccacttgccg ctgtattttt aaatgcagta
    14941 tagataggaa tatctagctt tttaattttt gccatttctt tagcaatctc agcactttca
    15001 tatattcctc ccccaggtga atttacttct aataacactc ccttaaccgc tttgtcttct
    15061 tgaattttct ttagctgtgt taaaaaattc tgatggttat attgttccct actaaaaaga
    15121 ttgctttcac ctgtatctgc aataactcca ttgacggata gtttgacaat ctttttattt
    15181 gatgcgcctt cttctaacgt ttcttctgtg atttcgttag atccgtaaaa aatcttattt
    15241 attcctgtta gggttgtatt tgatgcttcc tctttatctt ttcctggaat tagcgcgacg
    15301 ataatggata gtaacaataa tccgcacgct actcccacag caatccatct tcttttattc
    15361 atataaactc ctcctatatt cttagtaaaa ataattattt tttatttaga aacacatcga
    15421 caatttgttg ccaatatgtt ttttctccta caattaaaga caactctcca gttaatccat
    15481 aacgaaacgg aaacgattga gttgttttta acgttccttt cactgcataa aaaacacctt
    15541 tctcagtggc agtagaattt tctgaaattt catctaaagt tccgtcgatc gtaatcggag
    15601 ccccaccttt ttgatccaat ttaaaatgaa ccttcatccc ttctttaata taggtacttt
    15661 cattcgcagg taaaagtgct gtaaatttca tttttgattt ttcgtggatc ggataaattt
    15721 ctgcaagcac tgttcctttg gctagttctg cttgtccctt tgtttcttca tttaaatgaa
    15781 ccgttccaga tacaggagct tttagtattc cttttgaaag ttgatcgtcc aaacttttga
    15841 taactgactg gttcttctct tgtttttcat ttagctctgt aactgtttgt tttacagttg
    15901 ttattgcttg ttctagctct tgctttcctt tttccgtttg actaattctg tcattctcag
    15961 aagtagttgg tttaactaat ttagcttttt ctgactgata ctgttctact tcttttttta
    16021 gttgctcaat ttgttcattt atgcttgctg aaattgtcag tttcacttga tttttttgat
    16081 catcagaaac attatttagt tgttcttgcc aattctcata gtttgccatc atttcttttg
    16141 aaaaatcttt taatgattga ttattactcc aagctacctg tacttgttgc cattcttgta
    16201 atttactatc tgaactctca atttgttttt ctagttgtct ttttgtcttt tcgtatactt
    16261 ctaattgctt ttgatcattt aattcacttt gcttcaaagc gtagcggagt gattcttttt
    16321 ctgacaacat gctctttaat tgattactgt agccaaaact gtcatccgtt gaaaacaaat
    16381 tttttccttt acttatactt tcaataaata gctgagccat ctttatttgt tgagtaatac
    16441 gttggttttc ttgttctatc tgagcctttt cattctctat taaagaacaa tccaatctaa
    16501 ccaacacatc gtccttatga acaaattgat tttcttttag gaagttttcc attattttag
    16561 cttctaatgg cacttgtaac ttctctattt tttcggggtt caattgagcc gttgtccgaa
    16621 taacaacctc ttttttagca aaggttaaaa acaatccaat aatacataaa aaaagaatta
    16681 cagggtataa cacccaacgg tagaagctat gatgttgttt agtatagata ctagaatgtt
    16741 cgaaccaatt attattctgc ataaattgtt tccctctcct agatttccca taatttttga
    16801 tagataccat cggcaaaacg aagttcatcg tgcgttcctt tttctaccaa atgcccttca
    16861 tggagaacta aaatttgatc acatgctttt gctattggta aatgatgcgc aataaaaata
    16921 atcgtttttt cttttaaatt gaggagataa ttcataattg catgttctaa caaggtatct
    16981 aatccactag ttgcttcatc taaaattaat atgtccggat tttttaataa agcccgtgct
    17041 aaggctaatc gttgtcgttg ccctcctgaa agattatttc caccttcttc caacaatgtc
    17101 tcgtaacgta atggctgttg attaataaat tcatttagtt ggactatctc acaaacttct
    17161 attatttgtt cgaaacttgg tgggctatct aaaccgaata taagattctc aatgattgtt
    17221 ccactaaaga aaaatgactc ttgaggcaaa tatgtcactc gatcgcgtaa tatctgaaaa
    17281 ggaatgtcta agtgattaat gtttccataa tggatcgatc cttctgatgc ttcataaaaa
    17341 cgaacaaata actttgcaag agttgatttt ccagaaccac taactccaac tatagccgtt
    17401 ttactgtgcg aaggaattgt acatgaaatt tcgttcaacg ttggggcctt catgctatac
    17461 gagaatgaaa cgttttttac agtgatatct tgttgaaata attgttcaga aagcatatat
    17521 tcaaaagact ggttcgattt ttctgaatca atcgcgaaaa tttcatttaa acgattattt
    17581 gcaacttgag ccgtttgcat tttcacttgt aaattaataa tgttttgtaa aggatctgtc
    17641 aaaaatacta gtaaagcatt gtatgtgata agttgaccta gactaattct attatccata
    17701 acaaaataag aacctagcca taaaattaat gcactgctaa ttaattgaat caaatgttta
    17761 attccttgtt gaatattatc aagcgtaacc gtacgaaatg attttttcat taatttaaca
    17821 aattcatggt ctatacggtt atatactttc tcttcaccgc tatatgcttt aattgtttct
    17881 attcctttaa gactttctat gatactagaa tttacagctg caccggctgc catttcttcc
    17941 ctgttcgatt tttcatagct tttcacgaaa gcgaatattg caactacata aaaaggcaaa
    18001 gagcatagag tgattaaaaa caacgtacta ttctgaatag ctaacgtaac cccaacaagc
    18061 aacaccatac caatatctaa aaatattgat aacgtagcac ttgctaaagc atcaataatc
    18121 ttactggcat caagaaaacg agaaataatt tcccctgatt ttctcgtagc aaaaaaattc
    18181 attggtaaag ttaacacatg tttgaaatac tgaagcataa ttgccatact cattcgctgt
    18241 cctaaaataa taagaagata actacgacta tattcaaaca atacccgaaa taaatagaca
    18301 gcgatcaagc caatggaaat tatatttaaa gttgaacgtg cttgattagg gatgaaaaaa
    18361 tcaagaatac cttgaaaata atatgagctt cctatgccaa aaaacgtaat gaaaatcgat
    18421 gctaaaacga tgtggaatac taatcctttt tgtttccaaa ttataggcaa aaaagaactt
    18481 aatccagcta ctttttcttt aataggaata taagtttctc taggcatagg taataaaaga
    18541 atacctgtcc attctttttg aaacgcttca atcgtttttc tattttttcc attagcggga
    18601 tctgcaatcc atagtacgtt tcccttcgtt ttataaatta caacgtagtg catatagctg
    18661 ttatcaacca atatatgtgc aattaatggt aagataagat ctctttcttt ccagatctca
    18721 ctatctgctt gaatagccat acaatcaaaa gacaattttt caaatgtctt tttcaatcca
    18781 aatgctgaag taccctctaa atcagtccca gataggtccc gtaatttatg aatcgggata
    18841 tcagttttaa aatattttaa aatcatcgaa aggcaagcaa caccacaatc tttttcatct
    18901 tgttgctgca caaaaggaaa tgattttatc acttatctaa cacaactcct tctaaaaaat
    18961 ttttatagaa aaattctcaa tatagcttta atacagtgaa aatattgtct cataattcca
    19021 caaaaacttt gaaaacagtt cttgaacact aactttttca ttcctgaatc aaatttattt
    19081 tggaaatttt actattcaag aataaacttg ataagtttca ggaagatttt tactgttaat
    19141 caaatacgta tgttacagta gcaccgtaaa aaatattatt taaagaagcg tgtttaaaca
    19201 tgcaaaatgt aaaggaacta agtattgtgg aaatgcacaa actgttggtg gaggcaataa
    19261 tgcttgggga aaattggggc aagttgtagg tggacttacc acaggggcag taggtggtgc
    19321 aggtttagga acagcaattt gcggaccagc ttgcggtgtt gttggagggt tatatggagc
    19381 tgtcgctgga ggtgctgcag ctggctggga tgctcgaaaa aaataaaaaa ggagaataag
    19441 tagtatgcat attaaaaaca caaaaacaac atttatatta tcttcagaag agttgaaaaa
    19501 tattcaaggt gggagtgccg tgggagtttt aggcactact ttttctgggg caacagcagg
    19561 agtaaaactt tgttcagccg gaggacctta tgcaatagct gcttgtggtg taggtggagc
    19621 tttattaggt gctggattca gcatgtggac cggtgcgtaa acaattaaaa aatatcaaac
    19681 ctcaagattg gtttgtgtcg attacgaaca taggtatgtt ctttatcttt tcaaaagttt
    19741 ggaatggaca gaacttttta ctaaagcttc ttgtgctagt ttttataatt atattaaatt
    19801 tttatctttt attaaagtca gataaaaatt ctttggaaat gtaatggtag agatattttt
    19861 acaaaaggac ttgcagcgct gtagttggtg ctgcaggagg acctatttcg gccgttacag
    19921 gaggtattgg taatgtactt gtcggatgtg cattaaagcc tgttcctgca agttaaattt
    19981 ataaaaacag gaaagtaatt atctcaaatc ctatcaagta caatcatagg attgcacttg
    20041 acaggacaaa ttttttaact aaaaaatgaa aaacactttc taaaaattag tagaatttgc
    20101 caaatctttc gcatcttcca ccatacattt aattttaatt cccctttatg gtacttaata
    20161 aaaacaagaa aagaactatt catttggccc ttttttggtt ccagaccata gaaatattcc
    20221 tccagtaact aatattgctg ttatgcacgt aactaataac agctataaaa attggtacaa
    20281 ctttaatagg attcagaaaa atttgcacta gtgaaggaat ctattttatt agaaaaatgc
    20341 aatctcccta aagaaaaaac cactaaacag tgctttcttt caacttctcc ttaatttttt
    20401 gtgctttccc taaagtaaag tttctggcca actctgaatc aaaatatagt gaacgttttt
    20461 taaaatctat ttctttaacg ttaaagatat ttactaaaca cgctcgacta attcttgtta
    20521 acataggata tttcttttca agctcactaa ttcttccata aaattcgtac tgcccatctt
    20581 tagtacacaa tgataatcta tgtggtaatt ttgaagcttc tacaaaataa atgtcattta
    20641 tatcaaaagt aaatgtttga gaacctatgg aaaaaacaaa tgcttgattc gtaacctgtt
    20701 ttgttgcatc tatcctttct tgcgctaata acaataactc aacaatctcg tttcgatact
    20761 catctagtgt ttgatctttt gttacaaatc ctaacgtttc aactcttctt tttattgtta
    20821 cgggtaacat ctcatcatga gtagttgtaa aaatgatttt tgcttgaaca tcatattttc
    20881 tgattacttc tgctaattct ataccgttaa cttcatgatt taaatcaata tctaagaaat
    20941 atattccttg ctttggtcgg aattgtttga ggtatttttt aacttctaac ggactttgtg
    21001 ttttcaatac tatcttaaat actttatcgt gaaaaagaat gaaattatca ataattcgtt
    21061 ctaactgatt taattgtata atttgatctt cacataatat tattggataa ctcataaatc
    21121 ctccttccct caaaacaaca aaataacttg agtagtaaat tgatacggat cgttttgata
    21181 gttcacaaac atattgggat tctttttatt gatttcctct atactagata aacctaaccc
    21241 ttgatgtccc ttttttgttg ttattccttt tttcattaga gtatctatag agagtagtat
    21301 ctctctacaa ctattcgata tcgaaatttc tatctgttta tcatctcggt aaatagctag
    21361 agacagttct ctatcttgac tctctataga tgcttcaatt gcattatcga gaataattcc
    21421 aagcacccta atacagtcaa atattggaac aggaacttca ataatagtac ttggacattc
    21481 gaatttacaa caaatcttat tgttatttgc ttggtatagc ttcgctatca acaaactttt
    21541 caaatattca ttttttatat tttttaaata acgatattca aacttattgg ttagataaga
    21601 attagaatag atctctaatt cttttatttc tttttccaat atcgaatcat ggttttgatt
    21661 agcgatttct tttaaactca gcaataaatt tttatagtca tgtctaaatc tggcaaattt
    21721 ttcttgatct ttttccagtg aatcagtata tttttttaga taaaccaatt cttttctttt
    21781 caattgctgt tcatattgtt ctcgttgcct aatagttatt ctaataaata aaaatagaac
    21841 aacaaacatt tgaatgatta aaaatattaa gacaccaaac acaaaatgat caaatacttg
    21901 atattgatga gcaacataag aaacaaataa accaattgta agtaaataaa tcatgaatat
    21961 agcagtaagt ttagaactgg actgttcaac aatcctattt atagctaatt ttctatataa
    22021 ccaaataaac atcagcaaaa acaaagaatc aagcattatc tggaatacta cataaccata
    22081 cccttttatc ccttcaaatg aaaacatata cgtcataacc atggaagtaa taatagatct
    22141 gaaatcatca ataagcatac ataatagtaa tttatttaaa agcactatat tagttttctt
    22201 cttttccttt aatataaaat aacttccgat tataggtata gctgcggaaa catcagtaaa
    22261 taattcaaca aaaaaagtga gtggtatcaa taaacataca aaaagatatt ttcttttgtt
    22321 aagatcagta ttagtcatat aaaataagag aaaaaagaaa aagtttccca cgaacattct
    22381 taatagataa gcttttgtat cgatagtaat caagagatcc cctcctgatt ttaggatatc
    22441 ataaaaaaaa ttttagttac actttttaaa taatgaaaaa acacattcca ctaaatttga
    22501 tgccggtttt ccttgaggtt ttgttccagc acctccttta atttttttaa gctcttgatc
    22561 tgaacattgt ttagcattta gtctattttt ttcttccatt acgattcccc ctacaaacta
    22621 taaatacttt tatgtcactg attcaatata cctatttttc taatcaaaaa attttgagac
    22681 atatttaata ttataagtat cattaaaatt gagatttatc tccataatct gctcgatata
    22741 aaccatttat tccagcagtt cttccaattt cactcaaatt tcttattaat tcctcttgat
    22801 attcagtgaa tcttatttta ttagtataag cagtaaaata tagataattc accaatctat
    22861 ttattaaagg accgggatct aattcatatt tttgtttttc taattttaaa tatacctttt
    22921 gtaaaacctc aagaatatca gaatatttag gatctttact tatagatata tcattatata
    22981 attcatgaac aatttgctta gcattttttt tcattttagc acttccctgg aattgctcca
    23041 cctaaaaaac cacctataga cattcctgca atacaagtag ttgccttggc ccaatcgacc
    23101 gtacatttat ttttagtgca atacactcca tttccataat attttccact atgagtggta
    23161 cccccataga taagttgtgt ctctttaata gacaaaattt ttaaatgttt cataatctaa
    23221 tcacccctaa attaatgttt ttagactatt attctaacat tcattaaatt tcaaaaaaca
    23281 attccttctt gaaacgtagc aaaataattc ctgaataaga atttaatcac ttttaagtat
    23341 ataaactatg tatattcttt aatatttttt gagaatgcac ttcgtacata ataaacttta
    23401 atcacattag tctttcatac ctacgatcga tctctttgac tcgcacccat aaattcataa
    23461 tagtttgtcg gcgtctttgg acgtttcgaa gatgagctac gcattctctt tttttataga
    23521 caaaaaagat agagacgaac atggagcttc caaatttgga tatttgatcc aattttggaa
    23581 gctccattta tttcgtgtct gtctttttat tttttccagc tttcgactaa ttcttggttc
    23641 tctttgatcc agtcttttgc tgcttgctgt ggatcttttc cattgttgat ttccaacata
    23701 actttttcca tatctttttc tgaccaatgg aaattgtcta atactttgta agcttctggc
    23761 tggtcttctt tcaatccttt tcgaaccatc gtatggatct gctcttcgct tcccattccg
    23821 ttttcaggat cttctaagta tttcagatca tatttggcaa acatccaatg aggtgtccat
    23881 cctgtaacta caattggttc gtgttttttg atcgcttgac ctagtgcaac ggtcattgct
    23941 cctgaagaag atgtctctac tttccagtct ttcaagttgt catatttttg gatcgtgttt
    24001 tcagcagccg taactacacc agctcctggc tcgattccta tgattttctt acctgcctga
    24061 tcggttaact catcgatcga atttacatcc atgtaggctg gcactgctaa accaactttt
    24121 gctcctgtca aattggcacc taggtcttcg acttgatctt tatattgtgc atattgtgaa
    24181 ccatgagttt taggtagcca agctgaaacc atggcatctg actcgccatt tgaaacagat
    24241 ttccacatga ttgaattatc taatggcgtc atcgttacat catagcccat ttgtttcaat
    24301 acttcaccga ctacatttgt tgaagcaact tctgtatccc attcaacata agataagttg
    24361 atacgttttg tttctttggc agatgaaaaa ctccctatac caatcgcacc taagatcact
    24421 actactacag caccaatgat cagtccttga cgttttttac ttttctgtgt tgttgctcct
    24481 gcagcttttt tattgtttgg ctggttcaaa tgctgtgtaa aacggtcaat gatgattgct
    24541 aagataacta atgcaacccc gttgacaaat ccattcccga cttgtgctct ttgcaatgct
    24601 gataatacgc cgcgtcctaa gccgggtgca ccgatcatag aggcaataac gaccattgaa
    24661 agtgacagca ttgttgtttg attgatccct gccatgatcg tacttttagc taaaggcaat
    24721 tctagtttga atagtttttg acgacttgtg ctcccgaatg aatcagaagc ttctactaat
    24781 tctttaggaa cttgtcgaat ccctaaattc gtaaaacgaa cggttggtgg cagagcaaag
    24841 atgactgagg caaatacccc tggaaccatc ccgataccga aaaatgcaac tgctggaatc
    24901 aaataaacga atcctggcat tgtctgcata aagtcaagga tcggtttgat aatactttgg
    24961 gctttactgc tttttgccat caagatccct aatggtaccc caatgatgat cgagatcaca
    25021 ctagataaaa gaacaagtgt gacagtattc atcaaatcat tccatagacc ttggttataa
    25081 ataaaccata gaccgattaa tgtgaacaac gtaagtcctg gacgtttctt agaaataaag
    25141 aaagctgcta ccgtcaataa caagataaac aaaggagctg gaatcactaa cagtaaattt
    25201 gtaatccccg acatcactgc ctgtccaatc gtttgtaaaa atgaaaatag gccagaaaaa
    25261 gttgtcgtaa accattctgt gatattttct acccagtttg ccactggtaa ttgatagttc
    25321 aatagattat tcatgttcac tcacctcgct tgtttctgct aatgcttcaa tcacactacc
    25381 tcggatgacg acacctttta attttccatc ctctacaact gcaagtggag tcggtgagtc
    25441 ataaataata ttgaaaatat cacttaccac catgtctttc ccaatcaccg tcacattttc
    25501 atctaggaag tcgatcaatg gacgtttttg cttcctagct tctaacgctt gatctgcagt
    25561 gatgatccct ttcaggtgtc tctttctgtc aacagccatc agcatgctga cttcttcatt
    25621 acgcatcctt gtcaatgcaa cgtttggtcc atcagattcg atattcgtcg tcaatgcagg
    25681 taccatgatg ttttgagccg taagcacttt ggaacgatcg acttcttcca caaattcacg
    25741 tacataatca tttgctggat tggtcaatat ttcttcacct gttccgatct gcatgatttc
    25801 gccgtctttc atcaaggcga ttctgtcccc aatccgtaaa gcttcattca aatcatgggt
    25861 aatgaaaata atcgtttttt gaacattggc ttgcaggtcc agtaattcgt cttgcatttc
    25921 tcgccggatc agcggatcaa gagccgagaa cgcttcgtcc atcagcaaga tctcaggatc
    25981 atttgctaaa gctctggcta ggccaacccg ttgttgcatc ccaccagata actgactagg
    26041 atattggtct ttaaatgaaa gcaaactaga attttctaat gctttttctg ctttttcttg
    26101 tcgttcttct ttaggtacac cacggacttc taacccgtat tctgtatttt ccaagatcgt
    26161 tcgatgtgga aacagaccga agttttggaa aaccatattg attttatgac gacggacttc
    26221 tcgcaattct tctttgctta acttcgatac atcttctcca tcaatataga tactgcccga
    26281 agttggctca atcagacgat tcaatagacg gatcaatgtg gatttcccac tcccggaaag
    26341 ccccatgatc acgaagattt ctccttcttt tacgtcaaaa ttcacgtcat acacaccaac
    26401 cgttgcaccg gttttcttta aaatctccgt tttcggctgg tgatcattca tcatatctaa
    26461 agcggcttgt gtctttttac caaatatctt tgttaaatgt tttacttcta cttttaccaa
    26521 acaaattctc cttttttatg taaattcatt tttctttctg aaaaaagtga ccacactatg
    26581 ttaacatcat gtagtcactt tgtcaaaaat gaaagaaatt tgcttgtcca aactgaaaaa
    26641 aacttggcta aatctttgta aataaaaggt ttagccaagt taatattttt ttaatatttc
    26701 acacaatcat tctgcaagct gatgctccgg gtaaaaaaag tttgtcatac gctgtagtgt
    26761 atattcattt ccaataaaat gaacgatgtc ccctgccgta aatttagcat aggggccagg
    26821 tgaaacaagc agttcttcat tatgagaaat tgcgataact gtggcgccag tcgcctgcca
    26881 gatattcaac tcgctaattg aacggtccag atgcattgct ttttctgata aagataattc
    26941 aaacggaagt aaaggattca tcttatgtat tcgcttcgtt tgattgacca gctgatccaa
    27001 taattgagaa aaatgattca gctcatcttg ttgcttctcc acacttgcca tgatttctgc
    27061 ttttgtatct tggatggatt gtacatcttg atattgcaat aggaaatctt ttgctttttc
    27121 cttcgaagca acaaatgccc cacttccatg ccgtacttcc atgattccaa gatctaccag
    27181 cacattgata gccttgcggg tagtctcagg agaagcattg tacgtactgg caagtgttga
    27241 gcgggcatgg agcttctcac ccactttata tcggttttca acgatacgtt cggctaaatc
    27301 aacagcaatc tgctggtagc gcgggcggac gatttttttc tttccagaca ttttctttcc
    27361 tctttctttt tttactttcc ctcatcttac tatgctctag caaaataagc aaaaaagggg
    27421 agaatagcct cttgcaacga ctgatcatcg cttgatctgt tcctttttta ctgggcaagc
    27481 tgtttgacag tcatcacaat tcttaccgga ttttaaacga gtatagacaa ttgcgcctgc
    27541 acttccaaag attaacacac ttaataagaa tgtcgccatc ctattcctct ccttctaatg
    27601 acaatatagt ataaaactgg ttcttggatt ttggctgacg gaacaaaaca taaacgagtc
    27661 ctatcatcag taaaatagca agatacgtcc ctaacgctac ctgtccaccc tccaataagt
    27721 gtcccaactg ataaatcaca aaactaacta aataagctaa accgcattga tagcctatgg
    27781 cgatccaagt ccatttcttg gcattcattt cccgatggat agccccaatt gccgcaaaac
    27841 aaggcgcaca aagtaaattg aaggctaaca atgaataagc tgctgcggga gtatatgtgt
    27901 gttgtagcac ttgccagatt tctctgccat tttcggatac ttccgcatga ccaaacaaaa
    27961 taccaaatgt gccaataata ttttctttag cgaccaatcc tgtaatcgct gcgactgttc
    28021 cttgccagtt tccccaacca agcggctgaa aaacaactgc caggattcgc ccgaaaaagg
    28081 ctaagatact ttggtcttca gaaacaggtt gagcataaaa attataagaa gagctgaacc
    28141 agatcacgat actagaaaca aagataatcg ttcctgcttt tttaacaaaa gacttgctgc
    28201 ggtcataggt ttgtcttagg accgctgacc attgaggaaa atgatatgcg ggcaattcca
    28261 tgataaaagg agctgtatct ccagcaaaca aacgtgtttt tttcaagctg attccagaga
    28321 aaataattgc agtcatacca agaaaatagg cagaaggagc tacccaagat tgatgaggaa
    28381 aaaaggcccc tgctactaag gcaataatcg gcaactttgc agaacaaggc atgaaggttg
    28441 tgaccatgat cgtcaaacga cgatcttgct cgttttcaat cgtgcgactg gccatgacgc
    28501 ctggcactcc acatcctgta gcaatcagca taggaatgaa ggattttcct gaaagaccga
    28561 atttcctgaa aagtcgatcc atgacaaaag cgatcctcgc catatatccg cagtcttcca
    28621 gaaagctcaa gcataaaaac aatataatca attgcggtag aaatcctaac actgctccca
    28681 cgcctgcgat gatgccgttc aagatcagct cctgcatcca tcccgctact tgccattcag
    28741 ctaacaatct gccaacatgt tctggtaacc atgtaccaaa caatgtgtca ttgatccaat
    28801 ctgtccccat tgttcctact gtttgaatag ccagataata gatcagccac atcacaaatg
    28861 cgaagatcgg caaggctaac caacgattcg ttgcaatctg atcgattttg tcactcatcg
    28921 ataattggaa agaatcattt gacacaacac agagtgtaca tagttgggta ataaattcat
    28981 aacgttcatt gaccagaatc gtctcactat cgtcgtccaa tagtttctct gttaactgga
    29041 tcagttgctc gatctctttt tgctgagaaa ctgctatctc gtaatcctct cttaccttct
    29101 gatctcgttc aaaatatttc attgcatacc agcgtttctt gccgctttgt tctcctagta
    29161 catcttcaat ttcatgtaaa gctgcttcta aacgtggatc atatgtacag ggaacaggaa
    29221 tagaaggccg cttttttgca gactcctgaa tcttttcgat tagtttttcg attccttgct
    29281 ttttcaatac gctgattggt aaaactggta caccaagacc ataggaaagc ttttctagat
    29341 tgattttttt tccttctttt ttgatgacat ccatcatatt cagaccaatg atcataggaa
    29401 tgtctaaatc caataactgc gtagttaaat aaagatttcg ttctaaattg gtagcatcaa
    29461 taatgttgat gatcagttca ggctgttcct gaaccaaata atctcttgca atcacttctt
    29521 ctggtgtata aggagacaaa gaatagatgc cgggtaggtc ctgaatatga atgttcggat
    29581 tttttttcaa cgatccttct ttttttctac tgttacgccc ggccaattcc ctacatattg
    29641 attcgaacca gtcaagagat tgaacaagct agttttcccg ctgtttggat ttccgactaa
    29701 cgcgatattc attctttttc ctccctttgt atcaagatta gttcggcctc tgactttcgt
    29761 aacgtcagtt cataccctcg cactgtcagt tcgattggat ctcccagagg ggctagtttt
    29821 cggataacta tttttacatt tcgcgtcaat cccatatcca ttaaccgtcg cttcactgcg
    29881 ccttgtccgt ggattgctac gacgatccca gtctctcctg cttttaattg atcaagagaa
    29941 gtccagcttt cagaggaagc agtcttttta ttgacaaaga tttgacctag tatttcccga
    30001 cttactgcca ctcgatgact ttttaccagt aaaatggcat tgttgcctga taaattgacg
    30061 acgacgattt tacttccggc aacgatcccg atattttgca aatggcgttt tgttttttct
    30121 tctgtttcga ttcgttcgac ttgataaacg aaattctgct ttgcctgcgc taaggtctgc
    30181 atattgattc ctctcttgtg aaataaatca tgtattaaaa tcattcatta tatgttctaa
    30241 ttttcttacg tgttacgcaa ataaatgaga atcattctca catagaatac tctcggtaat
    30301 tgagaatgtc aattatactt gtgatattat gagcgaatct ttagtattga tagataaaaa
    30361 tgagaaaaaa atatttcttc atagttttcc acaatttttt ctctattaaa tttgctattt
    30421 tcccacacga tacttgtttt cagctctttt ttcaaaaaca caaaacttag tattccacag
    30481 tttccacaac acaatatgta gtgtttgttg tttgactttt ttactaagag ttttatacta
    30541 tctattatag ataataagaa tgtgttagag gaggcactca ccatgaacgt aaaaatcttt
    30601 tctaaaaata attgtatgca atgtaagatg gtcaaacggt ttttaacaga aaatcaaatt
    30661 gcttttgaag aagtcaatat cgatgaacag cctgaagcag tagactggtt gaaagcacaa
    30721 ggattccaaa gtgttcctgt cattacttct gatgcagaaa cagttatcgg attccgtcct
    30781 gatcagttgc gtaaacttgc cagctaacat gactaaaaga atcaaaacgt gatacatgga
    30841 tttgaagggc ttgagacagc accagttttt gtcgcaaact tccaaatcct tttttaaagc
    30901 ttaaaaacaa tgcaatgatt tgcaatcaag catcatcaaa tacgaaatga aggttgggcg
    30961 tacgtatgag tcttaaaaat ttacaagatg tcagttattt caagctgaat aatgaaatca
    31021 atcggccagt caatggtcaa atccctttga ataaggataa agaagcttta gttgcctttt
    31081 ttgaggaaaa tgtcaaacca aatacgatga cttttctatc tattatggaa aaaatcaatt
    31141 acttgatcga tcaagaatat atagaagcag aattcattca attgtattca ccatcattta
    31201 ttgaaaagct atatcaattt ttggacgagc aacatttttc tttcaaatct tttatggctg
    31261 cttacaaatt ttattctcaa tatgcgttga aaaccaacga cggttccgct tatctggaaa
    31321 cttatgaaga tcgagtagcc ttcaatgcgc tttactttgc gaacggggat gaagaattag
    31381 cacttgctct tgcagacgaa atgatccatc aacgatatca gccagctaca ccttctttct
    31441 tgaatgctgg acgtaaacgt cggggcgaat tggtgtcttg tttcttgact caagtcactg
    31501 acgatatgaa ctctatcggg cgctcaatca actctgcttt gcaattgtcc cgtattggtg
    31561 gcggcgtagg gattacttta tcaaatcttc gtgaagccgg cgctcctatc aaaggatatg
    31621 agggtgctgc aagtggtgtc gttccagtca tgaaattatt cgaagatagt ttcagctatt
    31681 ctaatcaatt aggtcagcgt caaggagctg gcgtggttta tttgaacgtt ttccatccag
    31741 acattattgc tttcctttca gcaaaaaaag aaaatgcaga tgaaaagatt cgcgtaaaaa
    31801 ctctttctct tggcgtgatc gtacctgata aattttatga attgacacgt aaaaacgaag
    31861 atatgtattt atttagtcca tatagtgtcg aaaaagaata tggtgtccca ttctcttatg
    31921 taaatattac agctgagtat gatcatctag ttgcaaatcc aaacattcgc aaacaaaaaa
    31981 tcaaagcgcg tgatcttgaa aatgaaatct caaaattaca acaagaatct ggctatcctt
    32041 acgtaatcaa tattgataca gcgaaccgcg agaatccaat cgatggcaag atcatcatga
    32101 gtaatttatg ttcagagatt ttacaagttc aaacgccttc tgtgattaac ggcaaacagg
    32161 aatatgaagt attaggaacg gatatctcat gtaacttagg ctcgacaaat atcgtgaatt
    32221 tgatgcaaag ccctaacttt ggtcaatctg tgcgtacgat gactcgtgca ttgacattta
    32281 ttacagatgc atctgatatc gatgtcgtac caccgatcca aaacggaaat aagctgaatc
    32341 atacgattgg attaggtgcc atgggcttac acacttatct tgcaaaagaa caaatggaat
    32401 atggctcaga ggattcatta gactttacaa atatttactt catgctgttg aattattgga
    32461 cacttgttga aagcaacaat atcgctcgtg aaagaaaaca agttttccat aattttgaaa
    32521 aatcagctta tgctgacggc acttatttcg aaaaatacgt aactggagaa ttccagccaa
    32581 aatcagaaaa agtcaaagca ttgtttgaag gcatttttat cccaactgct gaagattgga
    32641 atgctttgaa acaagcagta atgaaagatg gactgtatca tcaaaatcgc ttggcagtag
    32701 caccaaatgg ctcaatttca tatatcaacg atacgagtgc aagtattcat cctatcactc
    32761 gcatgatcga agaacgccaa gagaagaaaa tcggtaaaat ttattaccca gcgccttatc
    32821 tatccaatga gacgattccg tattacactt ctgcttatga tatggacatg cgtaaagtaa
    32881 tcgatgttta tgcaatggca caacaacacg tcgatcaagg catgagtttg actttattca
    32941 tgcgttctga aatcccagaa ggcatttatg aatggaagac aacaacgaag caaacgacac
    33001 gtgatttgaa tattttaaga cattacgctt tccacaaagg aatcaaatcc atttattacg
    33061 tacgtacctt tactgatgat gcagaagaaa tcggaagcaa tcaatgtgaa agctgcgtga
    33121 tctaatatca tagatagatt cgcttattca tattttaatt aaaggagcat tctcatgtca
    33181 gaaacatatt atgaagcaat aaactggaat gaaattgaag atatcattga taaatccact
    33241 tgggagaagc tgacagagca attttggcta gatacacgta tcccactttc aaatgaccta
    33301 gatgattggc gtacattgtc tcaattggaa aaagatacag taggacatgt atttggcggt
    33361 ttgacactgc tagatactgt ccaatctgaa agtggcatgg atcagttgcg taaagatgtc
    33421 cgcactcccc atgaagaagc cgttttgaac aatattcaat tcatggaatc cgttcatgcc
    33481 aaaagttatt cttctatttt tagtacactg aatacgaaaa aagaaatcga agaaattttt
    33541 gactggacaa atacgaatcc ttatctgcaa aaaaaagctg agcgtatcaa tgaaatctac
    33601 aaacacggta caccgctaga aaagaaaatt gccagcgtct ttttagaaac attcttgttc
    33661 tattcaggtt tttatactcc tctttattat ttaggaaaca acaaattggc taacgtagca
    33721 gagatcatca aactaatcat ccgagatgaa tctgtacatg gaacctacat cggttacaaa
    33781 ttccaattag gattcaacga gttacctgaa gcagaacaag aaacgttaaa agactggatg
    33841 tacaatcttc tttatgagct ttacgaaaac gaagaacgtt atacagaaga attatacgat
    33901 ccaatcggct ggacagaaga agtcaagaca ttcctacgct ataatgccaa caaagcattg
    33961 atgaacctag ggatggatcc actctttcca gatactgcca atgatgtcaa cccaatcgta
    34021 atgaacggga tttcaacagg cacaagcaac catgacttct tctcacaagt cggaaacggc
    34081 tatttgttag gtcatgtaga agcgatgaaa gacgacgatt atttgattgg attggaataa
    34141 ggatttattt taattcaaaa atttttcgaa aaataaaaag agtttagcgt acagatattt
    34201 taaatgtaca ctgaactctt ttttatgctt attcacttgt ttcttccagc acttttggac
    34261 tgtctaactt ttccgaaaca tgttccattc ttctcaataa atagattttc cggatattta
    34321 atattatcgt cttaatcact gcatagacag gtatgcaaat cagcatgcct aatattcctg
    34381 cgacacttcc tgctccaatc aataccaaga tgatcgtcaa aggatggata ttcattgatt
    34441 tcccaaataa caacggcttg atcaaatttc catctaattg ttggatcact aaaatcgaca
    34501 acgccatata caaagcttga aatggagaga taaacaaacc gacaatgatt gctggtaccg
    34561 ctccaataaa agggccgaca tacgggataa tattcgtgat tccgcaaatg accgcaagca
    34621 acaagctata aggctgatcg aatattctca ttgccaaaaa gctcattaca ccaataatca
    34681 aagcatctaa gatcgtactg ctgatatagg cagataatgt ttcgtttaat tcttttaccg
    34741 tttggcgtaa ctctttacga atcgctttcg gaaagaagtg agacaacgca tcaataaatt
    34801 tgtgcccatc cttgaacata aatagcaaaa taaatggaac ggtaaataac aaaataaaaa
    34861 attgcatcat aaatgaaatg atttttgaga cacttgcaga taaactgact aatatgatat
    34921 tgaacaaatt actaagagat aaatttgctg atgctaattg ttcttccaaa ttgaaatttt
    34981 taaactcttc ccgctgcgcc aattcattta accatttgct tgtttcatct gcatacattg
    35041 gcaagctctg ggtcaattga attgtctgtt ccattaactg aggcactaca ttcatgacag
    35101 ttaaaacaac taaaatgatt acgaccaaaa acgtcaataa aaaaccgaac actctcggga
    35161 tccgatgctt ttcgagaaaa acaacgattg gatcgaacat ataatagata aaaccagcaa
    35221 caagcaatgg taaaaaaact gccgaaagca ttttcaatat tggactaaaa atattcggca
    35281 tttgtaaaat aaagtacacg ccgatgatcg tgagtactag ctccactgtc cagaaaaata
    35341 attttgattg tttaaaacgt gattgcatac atctcctcca aggtcctttg atacttctat
    35401 tctatcattt aacaaagagt tacgcgctga gattttcatt tgcttaaaaa aaacaaaaaa
    35461 aataaacata ttttaatgag tagacgagta cttaaacaaa aacacggttt ggagtagtga
    35521 caaaaattat actgcagtcc ctttttccaa ataaacggtg ttcaaaagct tgcatcttcg
    35581 taataagccc agccaaacga aaaatataag gaactatttt tatttggctg ggcttattac
    35641 ttgatgtagg acatctattt tacaacctca gatcatttat tgcgcaatac tgactaaatg
    35701 caactttgtg atatttttgt gtacggacaa ctcctcgatc acatcggcat aagtgagccc
    35761 ttttggaaga tcaatcgtat agatattttt gtacactcgg tagtcatcaa cgaattttac
    35821 gtcaaaattc acatcttcga ttacgatatt tttctcttca aaataatcgg taagaaaatc
    35881 tttggtttct tttctatgga taaattggat ttctaacttt ttagtcgtag gtacatggat
    35941 cacgcgtttc actactgtga gtgcaatagc aatcccgata aaactgatga tcgcaatgga
    36001 atagtaaccc atgccgatgg cgatccctaa tccagcaatt gcccataaag aagcggcagt
    36061 cgtaagtccc gtcaccgatt gtttcgtgac gatgatcgtt cccgcgccta agaaaccgac
    36121 accactcacc acttgagcaa tcagccttgc ttcatctgaa cgaatcgttc cagcaagctg
    36181 tggatactct aaagcatctc ttaatgcacc actagcgatc tcaacttgga tcaatgcaat
    36241 gatacatgct cccatacaaa ctaaaatatg cgtacgcata cctgctggac gatttttata
    36301 ttgtcgttca aaaccgattg ctccgccaaa tagcatagcg atccctaaac gtaaaataat
    36361 ctctggaatt gtcaatacca tatcattcat ctaaacaccc tccagtccaa tatatcatgt
    36421 ctgaaaggag cagacaaaaa aagtgcaatt tttacctctt acgaaaaaag gactgtgaca
    36481 aaatttttgt catagtcctt tttatgaata aacggtgttc aatcagctga ccctcggtat
    36541 tactcaacaa acggcaaaat atggggagct atttttcctt tgtcttctct aatactcagg
    36601 tcaaaacgct gatttcacaa cctctttagc ctactattga aaattacaac ttacttgctg
    36661 cttcttcatc gatgatcaca acaacattgt cgtgattttg caatacactt gctggcaaat
    36721 gattcgttac aggtccttca atcatccctt tgattgcatc agctttgctt tcgccaaatg
    36781 ccatcaagac gatttcttta cttttcataa ttgaaccgat tcccattgaa acagcttttg
    36841 ttggtacatc ttctgcttta tcgaagaatc gtttgtttgc attgattgtt gattctgtta
    36901 agtcaactac tgaagtcgtt ccgtcaaatg aagcaccagg ttcattgaaa ccgatatgtc
    36961 cattttgccc gattcctaag atttggatat cgattggatg tgcatcgatg atttgatcat
    37021 actttttgca tgctgcttcc agatcttctg cttttccatc tggtacaaac gtttctttga
    37081 atggtttttt atcaaataat tggacatcca tgaaatgacg gtagctttgt tcatctgaac
    37141 cgcctagtcc aacgtactca tctaagttta cagaagtcat ttcactgaaa tccaaatcgc
    37201 ttgaagtcat ttctttatat aaagtaactg gtgtgcttcc tgttgccaat cctaatactt
    37261 ttgcaccttt gttcatacct tctttgatga tttcaaatgc tttttttccg ccttcttcag
    37321 cgttttttac acgaatgatt tccatagtga ttgctccttt atattttggt atagcccaat
    37381 tatagcattc tttttttctt tttacaataa ttagtataga ccaaattgca tttttttcat
    37441 tttcttgaca ataaatagga atccgtgtta ggtttcataa gatggttcaa tcaaacaatc
    37501 catgttgcat gaaaaccaag caagtgattc actgtggacg ctttatgtct gcagtttttt
    37561 tatgaaaaag gagttattat gagtatactg acattaaaca acattaccca gcaatttggc
    37621 gacaaaatcc tctatgaagg tgtcgatctg caattaaatg ctggcgaaca tcttgggctg
    37681 attggacaaa acggagccgg taaaagtaca ttgattaaaa tcatcactgg tgagatctta
    37741 ccagatgacg gacagatcca ttggcaaaaa aatattcaca aaggttacct cgatcaatat
    37801 gtggaagtcg atgaaacatt aacaatcgaa gaatttctaa aaactgcgta cgcaaaagaa
    37861 tacgaaaagg aagaaaaaat tgcttttctt taccaaacat atagcgagac cttcgatgat
    37921 tccttgctgg aaaaagctgg gaaactccaa acggaattag accaaggagt gttttatcaa
    37981 atcgacacct tagttgctga gatgagcagc gggttgggga tcgatgtctt aggtttagat
    38041 tcactgttga aaaatctaag tggtggacaa cgttcaaagg tgattttagc aaaactactt
    38101 ttagaaaacc cagatgttct gatcttagat gaaccaacca atcacttaga tgatcagcat
    38161 atccaatggc tgacgcagtt tcttcaggat tttgacggtg cgtatatcgt gatttcccat
    38221 gaccaagaat ttcttgatca gatcaccacc catatcgcag acatcgagtt tggaaagatt
    38281 actaagtata ctggccatct aaaacaagca ttgaaacaaa aggaacaaaa tcgcgaaagc
    38341 tatttgcgcc aatatcatgc tcaacaaaaa caaatcgaaa agaccgaagc ttatattcga
    38401 aaatacaaag ccggttcccg atcaacgatg gcaaaaagcc gacaaaaaca attagataaa
    38461 atcgaacggc tgacgcctcc agcttcagca agtaaagctg tctttgattt tccattctcg
    38521 cctattgtca cgacattagc agtggaaaca actgatttag tcatcggata tgatcgaccg
    38581 ctacttgcac ccatcaattt gaccatccgc tttggtgaaa atattgccat tcgaggcttc
    38641 aacgggattg gaaaatctac tttattaaaa acactgatcg gtgagattga aaaaataagt
    38701 ggcgatttcc acttcccaga taacacaaaa atcaattact tttcacaaga tctgtactgg
    38761 gaaaatccat tagaaacacc actacaatat ttaagcagtc aatttccaaa agcgactatc
    38821 aaagaattac gtcgccaact agctaaagca gggttagtta atcaattagc aagtgaacct
    38881 ctcactacat taagtggtgg ggaacaaact aaggtgaaac ttgcacagtt gacaatgaac
    38941 caaggtaatt tactgattct cgatgaaccg acgaaccata tcgatcaaga aacgaaagaa
    39001 agcttacaag acgggataca gaaatttcca ggaacagtaa tcatcgtctc tcatgaacaa
    39061 gaattttatc aagatcttgt gcaacgagtc attgagattg aaccaaaata aacgtttgat
    39121 tgaatagttg aaaaaaagga gctgtgacaa aagttttgtc acaactcctt cttctgaata
    39181 aatggtggcc aattagctga ccttcggtat tagctcaaaa aacggcaaaa tatgaggagc
    39241 tatttttatt tggctattct tattacttga tgcagaacag cttttcacaa cctcttttcg
    39301 tctatttttt attttcgaga tttctctttc ctttaaaaac aactgtttga aagaagaacg
    39361 cacatccttg aaaaacaagc ccgctaaccg ttacacctaa ccagccatac tgctgccaca
    39421 ttgtcgtccc tagcaatgaa ccagccgcac ctccaataaa gtacataaac ataaatacag
    39481 tattatttcg gttgcttgct gcttcaccta gcccttgtac tcgtgtttga ttggcgactt
    39541 gaccaaattg attcccgacg tctaataaaa taatagctaa aagcaaaatg gccaaatggc
    39601 ttccgccaac caataaagca ataaagctta ttgtttgcat aacaagtccc atatacacga
    39661 tttttctttc agaataagaa tctgccagtc gtcccacgat aggtgcagca actgctccag
    39721 acaaaccaaa aatcgctaat atccctgctt cgaatgttcc ccaattgtag gcgggactgc
    39781 tgatataaaa aatcaacgta gaccaaaaga tcgaaaatgt tccaaacatg aaaaatccac
    39841 tgactgccgc ttctcttaat agacgttgag aagcaactaa atgcggcaaa cttttaagtg
    39901 aatcaaggta tgaaacagct gtactacttt gctggacaga acgcggcatt ttccagtaaa
    39961 gcagaagtgt aagaattccg actgcacata aagcaaataa atagatcatc cgccaagaaa
    40021 aaagactggc aacaatacca gataccgtcc gagaaagcaa aatccccacg agtaaaccgc
    40081 taagcaatgt acccatgacc ttccctcttg cttttggtcc cgctagtacc gcaccgtaag
    40141 gaatgatgat ttgcggcacg atcgaaagta atcctattaa aaaagaagcg catgcaaata
    40201 acgtaaacga aggcgcaaaa aaagcggcca acagagagac ggcagataac gctgccattc
    40261 gaatgatcaa ttttggacga tccaccacgt cccctaaagg aactaaaaac agtaacccta
    40321 acgcatagcc taattgggtc aacatcgtca atatcccgac tgcacttgtg ctaacagata
    40381 aactagctgc tacttttgtt ccaatcggct ggatgtaata catattggca acaacaacgc
    40441 cacaagtgat tgataatagt aaaataagcg aagttgttaa aggttttttt tcattactct
    40501 tcattgattt cccccatttc ctatcttagt ttacaactta tggaaaagat tggaaataga
    40561 aaaatacaac tattcgccac acttattatt tgtgcttttg ttttccttgt tttttcttgc
    40621 gatctttata aatgaagaca actaacccta ctagcacagt aacacttgca accaacgtga
    40681 ctgcagtttt gttatatccg tgaaacagag cttctccacc acacgcatac aacacagacg
    40741 aagggatgac tccaatcacg atcgacaata tgatttgctg tagaggcaat ttcatcgcat
    40801 ctgcagcaaa attgaccata gaagatggaa taaccggtat catatagcct aacattacac
    40861 ctatttttgg atgtttcatt tgtcggattg cttgcaccca atgattcgtt tcggttttct
    40921 tatctaaaaa ttttaagcga tgcataagga aaattgcagt gatgttacca agagcattac
    40981 ccaaaatgtt gatgatcgca cctgtcagtg gtccaaagct caaaccagca atgactccaa
    41041 ctactgaagt aggaatacct ggaacagcac acatcaccgc tgtcaatacg atcaagagta
    41101 tcgatgcaaa agtcccatgc gaacgaatat gtgcgagtag ctctgcctta ctcgctctcg
    41161 gatttaaaaa taattggatg tctgtctgat attctaaata caaccgatag cccactacca
    41221 gtatcagaat gattcccaac gagatcaata tcaatcggat tattttcttt ttcatatttc
    41281 ctcctgaaaa aaatctatat tcattaaata atagtttaac ataaaaacaa aaaagcaccg
    41341 aaatccaaca taggatctca gtgcttttaa atagtaaaaa ttatttaaca gttacagatg
    41401 cgccaacttc ttcaagttta gctttcaatt cttcagcttc ttctttagat acgccttctt
    41461 taactggtgc aggagcgcca tcaactacag ctttagcttc tttcaagcct aaaccagttg
    41521 cttcacgaac tgctttgata actttaactt tttggtctcc agctgcagtt aattctacag
    41581 tgaattctgt ttgttcttca gcagcagcag cgccaccagc agcagctaca gctacaggag
    41641 cagcagcaga tacgccaaat tcttcttcaa tagctttaac taggtcgtta agttctagga
    41701 tagttgcttc ttttaactca gcaacgatgt tttcaatgtt caatgccatt ataatttcct
    41761 ccgtttaatt gttctttttt atttaatgct ttatgcggca attaagctgc atctccatct
    41821 tctttgtctg ccactgcttt gacagcgtaa gccacgttgc ggactggcgc ttgtagtaca
    41881 gatagcaaca tagatagaag tccttcgcga tttggcaatt ttgccaatgc tgtgatttct
    41941 tccaatgaag agactttacc ttcgatgata ccgcctttga tttctaatgc ttttgcttct
    42001 ttagcaaatt cgtccatgat tttcgctggt gcgactacat cttcgttact gaatgcaaca
    42061 gctgtaggtc cagtgaatac ttcgtccatg ccttcaaggc cagctttttt agctgcacgt
    42121 gaaagaatag aatttttgat aactttcatt tctacgttag catcacgaag ttgtttacgt
    42181 aaacgtgtta cttcatcaac tgttaatccg cggtagtcaa cgactactac tgatgcagct
    42241 gctgtaaatt tttcgcttac ttcatcaacg attgctgctt tttttgcgat aattgcttca
    42301 ctcatttttg agtttcacct cctgaatttt gatggaagag ttttttgcac tgaaaaggca
    42361 agtcactttt atagttactt tgctcaacca gtattattca tcacctattc acttcgttca
    42421 tagtgattct actcgctttg ctcgaaagga aactcctttc gctttgctca accagtattg
    42481 ttcatcatct cttcacttcg ttcatagtga ttcacaataa aaaactctat gccaccgcag
    42541 acatagaggg actattgaat atattcaata aacgtcctcg gtaggaaatt aaggcttgat
    42601 gccacctact gtcttcggta caagttaatt attaacctca actagcttag catgctaaac
    42661 tagttgagtc aagaattatt tttcagttgg atcaatcaac attctaatat ttaattagaa
    42721 agaagcttgg tcaacatgga taccaggtcc aaatgttgtt gtgatcgtta catttttcat
    42781 gtattgacct ttagctgctg atggtttagc ttttagcaat acatcatgga ttgctgcaaa
    42841 gttttcaact aatttttcat cgtcaaatga aacttttccg attggtacat ggatatttcc
    42901 agctttgtcc acacggtaag ttactttacc agctttcact tcgtttactg cttttgttac
    42961 gtccattgta actgtaccag ttttagggtt tggcattaag ccttttggtc ctaatactcg
    43021 tcctagacga cctacagtag ccatcatatc aggtgttgca acaactacat caaagtcaaa
    43081 ccatccgttt tggatttttt gaaccatgtc gtcgtcacct acgaaatctg caccagctgc
    43141 ttcagcttct tttgctttgt ctcctttagc aaaaactaaa acagtttgtg ttttaccagt
    43201 tccgtttggt aatacaacag caccacggat ttgttggtct gcttttttag ggtctacgtt
    43261 caaacggtat gcaacttcaa ctgttgcatc aaattttgca atgtttgttt cttttgctaa
    43321 agctactgct tcggcaacag gataaacttt acttgaatca acttttttta atgcatcttg
    43381 catttttttg ctctttttag ccattttggt tcctccttga ttgtggttat aacggttgta
    43441 cctcccacgt gttctatatc tttcaatata gagccaactg agaagctgct gtcttagggt
    43501 gtatagatta ttctacagtg atccccatgc ttcgtgcagt tccttcaacc atgcgcattg
    43561 ctgcttcaac gttagctgcg tttaggtctt ccatttttaa ttcagcgatt tctcttactt
    43621 gatcgctaga aactttcgca actttatttt tgtttggttc gcctgaacct ttttcgattt
    43681 tagctgcttt tttcaataga acagcagctg gcggtgtttt tgtaacgaat gtgaatgaac
    43741 ggtcttcgta tacagaaata acaaccggaa tgatcaaacc tgcttgatca gctgtacgag
    43801 cgttgaattc ttttgtgaat cccatgatat tgatacccgc ttgacctagt gcaggaccta
    43861 ctggtggagc tggagttgct ttacctgcag gaatttgcaa tttaacgatt ttttctactt
    43921 tctttgccac gagacatacc tccttaagtc cgtgatgtgg ttaattggag atgcatattt
    43981 ctcctcccac gttttatctg atctgaaaaa atccagacaa ataatgtgca aaacaatgca
    44041 cactggtaca gtatagcaaa tttatttgtt ttttcaagat ttttttctgc tatttttaca
    44101 ttttgcttga ataaacgcta aatttattct aaaaaaacaa caatttttcg ttctcatttc
    44161 ttcttttatg ttacacttgc gctagcatgg ttcaacagat gaaagcaaac aataacacgg
    44221 ttttttagac ccttgtacaa agattcctac ataacaaaat gaggtggaga aaatgaaaga
    44281 tttaaggtat agaagtgtct ttgatattat tggacctgtg atgattggtc caagtagctc
    44341 tcacactgcc ggagctgcta gaatcgggaa aatcatacgt agtatatttg gcgaacagcc
    44401 tgattctgta gatatttatc tatatgaatc atttgcaaaa acctatcggg ggcacggaac
    44461 agatattgca ttagttggcg gcctgttagg gatggaaccc gatgatgaac gtttagctga
    44521 ttctttgaaa ttggcatatg aagccggtat ggaagtcttg tttgttccta agagtgaaaa
    44581 agccgaacat ccaaactctg taaagatgct tctaaaaaaa ggaacacgaa agctttcagt
    44641 cactggcatt tcgatcggcg gtggcaatat ccagatttct gaattgaatg gattcaaaat
    44701 ttctttaagc atgggtactc ctaccttgat cgttgtccac caagatgttc caggtatgat
    44761 tgctaaagtg actagtatac tttctgagac caatacgaat atcggcacta tgacagtgac
    44821 acgggaatca aaaggtgaaa atgccattat gataattgaa gtagatgatc ctcaagtaga
    44881 agaaacggta aaaagactca aacagctgcc aaatatcgac agcgtaaatt atttcgatta
    44941 aggagctaaa aaaatgtttt tatcgattga agaattagta gatcaagcaa aagcttatcc
    45001 aagtgtagca gaattgatga ttgcagttga aatggaaatg agtggccgtt cccgtagtca
    45061 catcatcgag atcatggaaa aaaacctctc agtaatggaa caatcaatca acgagggaaa
    45121 agaaggtgtt acctccgtca caggaattac cggtggtgat gcaaaaaaat tagatgatta
    45181 tttaaatgag gcagactttt taagtggaga aacaatctta aaagctgtac gcaatgctgt
    45241 agctgttaat gaagtcaatg caaaaatggg gttgatttgt gctacaccga ctgccggaag
    45301 cgcgggtgtt gttcctggtg tgctgatggc tgtccgagat cggcttgatt tgacacatga
    45361 acagcaattg gaattcttat ttaccgctgg cgctttcggg ttagtcatcg caaacaacgc
    45421 ttctatcagt ggtgcagaag ggggatgtca agcagaagtt ggttctgcaa gtgcaatggc
    45481 agcagcagct ttggtttgtg caaaaaatgg gactcctcat caagcagcac aagcagtagc
    45541 cattacattg aaaaatatga tgggactgat ttgcgatccc gttgcaggct tagttgaagt
    45601 cccgtgtgtc aaacgtaatg ctttaggctc ttctcaagct tttatctctg ctgatatggc
    45661 attagcgggt atcgaaagtg tcattccgcc ggatgaagtc gttgctgcaa tgtaccaagt
    45721 cggacgtcaa atgccgtcga ttttcaaaga aacagcagaa ggtggcttag ctgttacgcc
    45781 aactgctaaa cgacttgcgg aagagatttt aaataagagg gcgtgataaa gctccttaat
    45841 ttcgagtatt aagagattag ttatcttcat aacaaaaaac gaagagagga ctaattgccc
    45901 ttctcttcgt tttttattaa tccatcaatt tcgtattttt tacttcatcg atcgtttttg
    45961 ttcctgcaag ttgcatcgtg atcgacaatt ctttgttcag gtgttcaaaa acagatgtta
    46021 ctccttctgc cccacctaga ttcaacccat aaatcactgg tcggccaatc gcaactaagt
    46081 cagcaccact tgccagagct ttgaagacat gctctcctcg acggacacca gagtcgaaaa
    46141 tcactggtac acgtttgttg actacttcgg caatttttgg caatacttca aaggacgcag
    46201 gacctccatc tagttgacgt ccaccatgat tggataccca gataccatct gcccctgcag
    46261 agatagcgat tactgcatct tctggcgatt gtattccttt tacgataact ggaagatggg
    46321 tgatttcttt gattgttttg atgtcatctg gtgtcaagcc ttgttttgca gctgcataaa
    46381 tttctgcgat tccttttcct tcgccattac cacttgcact ttgttcgcta tacgcagcta
    46441 agttaggcat tggtaatgga aattggaatt gattgatgac gtcttcttca cggtaaccac
    46501 cgagcgttga atctgccgtt aaaatgatag ctttagcccc tgcttctact gctttgttca
    46561 aaatgaactc attgaatctg tcgtctttac tcatatataa ttggaaaaac tgcggtgcgc
    46621 ctggcgctgc atcggctgcg tctttgattg tcgtatttgc ataagtgctg atggaaaaga
    46681 ttgatccagc agcagctact cctttagctg tatcagcttc ccctttttca tgtgccaatc
    46741 cttgggccgc tgatggcgct tggataatcg gtgtatctaa ttcaattccg aaaacagatg
    46801 tatgcaaatc ggctgagtcg attccgcgta atatccgtgg catgattttc tttgtattaa
    46861 aagaagtcgt attttctttc atcgtccact catcttcaga accaccgcga atatagccaa
    46921 aagctcctgc ttccatgcgc tcttttacac gaccttctag ttaggcaatg tttacaatat
    46981 cgattggatg ttcttcatta cttgtatgat aagtcatagt agatccttct ttcatcttct
    47041 tgattacata taaatcatac taaacttaca aaaagtaagc aaacatttac tctcagatac
    47101 ttttatcgct attctttcca aataaatcga cttacaagct gatctacttc ttggttttca
    47161 tgaagcatac tatgagaggc attttcacct gtcactactt tttcctctat ttcatttccg
    47221 cgttgcttca acaacgcata gaccgctaat gcactgttta acggtactgt tccatcactc
    47281 aagtctgttt catctagttg accagcaatc aagaaaaatc gagtggttat aggaatatta
    47341 ccgatcattt gctggtaatc ttgatagcgg ttagaaacga cagcaggccc ctttgctaac
    47401 tcatctgtca gagactgcgc actatcatcg acaaaatcat taaaaggcgc gccaattgct
    47461 gttaatgtct gaacttgtgg caatgacgta tcctgtccat acgttcctaa atagcgtagt
    47521 gcactaactc ctcccatgga atgccccact atgttgactt tatctatgcc gtagttttct
    47581 ttcagataca aaagacaagt tttgatccat tctgcttgat tccactcgtt atttttatta
    47641 tcttcaaaca atacttggac catcggattg tctgcttttc cagacaaatc tcctgttgct
    47701 tgtatttgtc catctgttcc tactgttaaa accaattctt ttactgcttg ctgatttttt
    47761 tccaaacgcc gcaacatccc tttaaaggaa ttttctgtcc cgctgtagcc gtggaaaaaa
    47821 agtgttggaa tagtggtttt ttctatcact ttactggatt ctgccgtttt ttctttatca
    47881 gaaacttcag tagtatttat cttcgtcgtc tggcaaccac ttaacgcaaa caaactgata
    47941 aggactaaag ctgctgcagt tgcacgtttg cataaatttt tgattggttc tgtcatacac
    48001 ctcttccttt ccatatagaa aaaagaaaga cttgaaaggc caatcatatg atcgacattt
    48061 caagtctctt tattaatcga ttttatctac ttgatcgaaa tcaagttctg tactggtttc
    48121 acgtccaaac atatcgatgt tgactttcaa tttttctttt tctccgtcaa cttctgttac
    48181 ttgtccttct aatccagcaa atgcgccttc gatgattttc acgacttcgc caacttctac
    48241 ttctagatca ttttgtcgca ggctcatacc gatagaacgc aagatatgat tgacttcttc
    48301 tggaagtaat ggtgctggtt tgcttccggc tccgtgtgaa ccaacgaatc ctgtcacacc
    48361 aggtgtgttg cggacaacat accatgaagc gtctgtcatg atcatttcaa caagtacgta
    48421 tcctgggaat gttttatgaa cgatttcttt ttctttccca tttttgactt cagtttcttt
    48481 ttcttcagga acaacgacac ggaaaataaa gtcggccatt ttcatacttt gcgcacgaga
    48541 ttcgatattt gcttttactt tgttttcata tcctgaatat gtatgcaaga cataccagtt
    48601 tttttcaaaa gattccattg aaggctcctc atttcattgt aaaataaaaa aacctcagta
    48661 cacccgaagt ttttctttcg cttcattata gcactaaaag tacgttgtgg ctagcgagtt
    48721 attttaaaat ccagccaaat aagctttgga tggctgtatc cattacgtaa aacatcaatc
    48781 cgaaaataat agaagtttcg atgactacta acgtatcttt acggagttgt tttctgcttg
    48841 gccaagttac ttgtttgatt tcatctttta cgctttttag aaatttcatg agacaacctc
    48901 ccttgctact gtttatttcg tttctttatg taatgtatat tgattacaat atttacaaaa
    48961 cttattgatt tccaaacgtt cgccgctttt tccttcactg actgattttg tgtagttgcg
    49021 agacccacaa acggaacaag cgagtgctgc ttttttcttt gccatttact tctgccccct
    49081 tgctgagaat cagacttata cttcataaca gtatcacgta actttttact tgtcaatttg
    49141 tgaaataaac tatctattgt tttggataaa attatgatat gattaatttg aaattaagct
    49201 aaaatgagac aattggaggt atagcgatgc tattaaaaac acttgtatat aagaaaaaag
    49261 atctgacaac cgttacagag actagtacat tagaagaagc attaaaaatt ttagaaactt
    49321 ccggataccg ttgtgtgccg atcttagatt cttcaggtaa tattttccgt ggaaacattt
    49381 acaaaatgca tatctatcgt cataaagcaa atggcggtga tatgacgctt cctgtcactc
    49441 atcttttgaa aaacgctaca aagttcattt acctggatac ttctttcttc aaagtattct
    49501 ttacgatcaa agagcttcct tatattgctg tccttgacag tgaaaatcat ttttatggta
    49561 ttttgacaca tagtacgttg cttaatatgc tctctcaatc ttggagcgta gaacaaggaa
    49621 gctatgtact gacaattgct tccacaggaa agcaaggaga tttggctgct attgcaaaaa
    49681 tcatttcaaa acacagcagc attgccagct gtattactct tgatatcgaa aaagacgaat
    49741 acattcgacg tacattgatc acgctaccgg ctaacactga agcgaaagta tgtgaaacga
    49801 tcgtcaacca cttagagaaa aagaattata aagtggtaga aattgaaaat ttgcaaaacc
    49861 aagaagcata atcaaaaagc gaaaaaagaa aacagctaat ctgctttctt ttttcgcttt
    49921 ttataattag acacgctttt caaaatcaag cgcgcgatct aaataataca tcaatggtgc
    49981 tgaaacagcc atgacgataa actcacttaa tgcaagcgtg ccataggttg tccaaaatgc
    50041 ttggccacct gttggaacta acatataagc aatcagtccc atgctgatgg taaagaagat
    50101 cgtgttcaat actaaacgca tctttacatt tttcactttg ttttgcaata aagctgtcag
    50161 gcctaaagaa agcaatgttt ggccgccacc aaaaaccaca tccatgatac caaaaccaaa
    50221 gaaggcatta tagacgatga ccccgcctaa aactccccaa agcaatttac ggttaaagac
    50281 aactaaatga ttcaaacttt ctgaaatacg aaactggatc ggccctgagg atacaggcgc
    50341 aactaaaata gttaacgcta gataaagagc catgatgatg ccatttacaa cgattacgga
    50401 taaccgttgt ctgcttttcg ttttttgcat tttctctcct cttttctcct agttttttta
    50461 acgcgggatg gttgatgaac cgcggttatg tgaaacaaac aataattata acagactttt
    50521 catttatttc aatccgtctt atctgctttt aaaaaagcaa aagcttaaac aatgtaaacg
    50581 tttgctaaaa atcgtgggat atggtataaa gtaagtgtaa ggggtcataa gaattcccag
    50641 taaagcagac gaagtaggat ctgcaagaac agaattgttg tgaaacttaa ataaataaaa
    50701 aaggatgtgg gaatttgagc aacctcttac tagagaacgg tctagcaagc agctgaagat
    50761 ctaagtggac atgccgaacc ttggaacttc tccttacgta agtaatggat catgcgcttg
    50821 ctaggctttt ttgtgttttt cggtcttcgg acctttttca ttttcctaga cttctgctat
    50881 aataaccaag aattaatttt gtaacagatt tttttgaaaa aacaagtttc tttcattcaa
    50941 aaaatagaaa aagcttgcta attattggtt aaccagcaaa caggagtatt aaaatatctt
    51001 gttttattga atagcaggag gaaatcatga aattccatta tcatatattg atcaatccat
    51061 cggcaggcag cggaaatggc tataaagtag cagaaagaat tttaccggta ttaaaaaata
    51121 agcatattga ctatacactt cattatagtg aatacaaagg acacgatgct gagattgctg
    51181 aaactttggc aaaagaaaca ttgattcctt ggatagaaga agaacagaaa acaatcgata
    51241 ctttccccct tttgatcatc gtaggaggtg acggcacctt acatcaggta cttgatactt
    51301 tctatcagat ggaagtagaa ttcccagttg cttatattcc agcaggttct ggagatgatt
    51361 ttgctcgagg ggcaggcctt ccaaaaaatc ccaaaaaagg acttcagctg attttagcag
    51421 ctcaatcacc agaaaaagtc cacataatgg cttatgaaga aaaaataagt gaaaaaaaag
    51481 gaatagctgt taataatttc ggtataggat tagatgcagc tatcgtccat gcgacaaatc
    51541 attcttccac aaaaaagcga ttgaacaaat acaacttagg atcattttcg tatttattct
    51601 ctattctccg tgctttattc actcaaaaag gatttccaat tctggtagat gcaggaggaa
    51661 aacaattaag tttttcaaac gcatttttat gtacagcaac gaagcatcct ttttttggcg
    51721 gaggaatcgc gattgttcca actgctgatg cgtctaaacc agtcattgat tttgtcgtgg
    51781 tcgaacgaat caatttcttt aaaatcttgt ggctcattct tttacttata cagaaaaaac
    51841 aattgaaatc gaaatatttc catcactaca caacaaacag attacgtatc gtttcaacaa
    51901 caccgcaaca tggtcaagaa gatggagaag aaatggaaaa acgacctttt gatatcacaa
    51961 taaccacaac taaacagttg ttttggtgtt aataaaagag gttttgtcag aagctacatc
    52021 tggaacaccg tttattcgga aaaaaggact gtgacacgac ttttgtcaca gtcctttttt
    52081 tactatgcag ttaattcttt gcccaattgg gttgccatcg atagtttctt tctttaccca
    52141 aaataaattg gatcattgaa aacaccgcag caaaagcaac taagacacaa ccattgaacc
    52201 aaaaagattc tgcaaatgtt tgattgtaac tgagtgtttc actgatcaag ttattatttt
    52261 gaacaaacca atatgttggt gtgaatgccg ctattttgct aaccatttct ggcaagtatt
    52321 ctgctggtac aaacacccca ccgataaagc aactgcctgt gataaaaata tctttgatcc
    52381 caccgctggt ttctgagttt tttaccaatg aagtgataca agccgaaaag ctaatgatcg
    52441 gcaataaaaa caagaaagta tttaaaatat gataccatac cgttatatcc cacgaggtgt
    52501 ggatcactaa cagaaccatt agaagtaaga agccactgaa caacagcagc gagtaactaa
    52561 tcaaactaaa ggttactttg cgattcaagt ttcgtttggt aatgggcgca ctctggtttc
    52621 gtttactgat ctctttgcga ttaaatgcta gattgatgac gctgaaaccg ctaaaaatgg
    52681 atagaaacaa cccataagac aagaaattaa aggttgtgcc cgtcaacagc tttttcatcc
    52741 gctgactata tcccgcactt agctcaactt ctccagtaac cgagagtgcc atttgtgtct
    52801 gttccatagc tgcatcgatt gttttatctt cttcttgaaa cagaatcagt gtttgcaaaa
    52861 aggtgttcac ttgctgtgta acaactgttt tagaaaaggc atctgggcga ctctgtatct
    52921 tgatcgtcgg catctttcct acttcgactt gttcggtaaa gtctgcaggc agatgtaaga
    52981 taatgtttac acgattaaaa taaagagcat catcgatttc tttttgtgag gttccatcca
    53041 atgtaacgac tgtttccttg tcattcaaat atttacgaag gccatcgact acaggcgact
    53101 cttcttcact aatcaaggcg attttcgcat cttgcagaga ggtattttca acatcaatat
    53161 tttgcgcaaa aaagaatgtg gcaacaacag tgataattac acctatcagt aaattcgatt
    53221 tatttgcttt aagcaatgtc caaatcgttt tataaagcgt cataacgcac ccctctttcc
    53281 atccaagcat ttcctaacgc aaaaaggaaa ataaatccga tcaaccatag aagattggta
    53341 taaaaactag ccaaatcagt gtagaaataa agtttataca aactttcgct gatcaagttg
    53401 acgagattta attgaccaac aatcggaata tgaagatcaa tccaatactt cacttgttcc
    53461 gaccccatca taccagcaaa aaagctcatc gcaatcgtca ctgaaatcaa gatgctatcc
    53521 ttttgcacca gattcatttt tggtatcaaa ttaccaacca atgtacctaa caaaatcgca
    53581 cacaacgacc ccagagcggt aacaatcatc aaccattgcc aacgttcacc aaagtctact
    53641 tgatagataa aacgaaagac agctaacata atataaatct ctgtcaaaac aatcgtaaag
    53701 cttgctgcca aattagcgat tgaaactaac gattgctttc taggaatcaa ggacaagcga
    53761 ataccatttg acgattgatt tgcttgctga tcctgtacat tgcggacccc ccacatcgtc
    53821 ccgtagagaa tcgccattcc aatcagagtg aagaaataaa aacttttgaa actcatatta
    53881 cgacctgcat gaacttcttg aaaagatact tcttgttcaa aaacagtcat gatgggcgcg
    53941 agatcaacgt tctccacttc tgccacttta ctcgaaatta taccaatacg ctgtaaaaat
    54001 tgatccatga cgtttttcat caacgtctga ctcattcctg cttgacccac atggagcgaa
    54061 acagatgaac catcaatgag ataaaaacca gccaaatcat ctgcatttag cttttcattc
    54121 gcttctactt ccgatagttc ctgtacttca aataatggtt tatcattgac ttcgacttgt
    54181 tctaagactg tggtaaaatt ttccgaaagc gctgtttgat ccgctttgat tacaattcca
    54241 gtattaatcg tttcgagatt gccaccttga tcaatctcgc caaaggccgc cataaacatc
    54301 aatcctaaaa gaattggaaa ggccaatgtc caaaacaaca tggatttatt tcgcagcagt
    54361 atttttgtgc gatatttata aaaatgccaa aacattattt cccctcctct agtctctcaa
    54421 atccttgcca gtaatctcta aaaagacatc attcaaggac gcttctttgg ttgctatttt
    54481 tccgtaactg atcttttctt cttgtaagat tgtaagaatc ggcaacaata ctgtatttag
    54541 ttcagtagtt gttacttgga gctgaccttt tttataagcg attccatcag aagctattgt
    54601 tcgctgacaa cacgttttct gggagtaatg ggatgtcgat cgtcaaacga tccgccgtcc
    54661 gtaccatatc ttttagagat tctttggttc ctttagcaat cacctgtcct tgatccatga
    54721 tcacgatctg gtcgcaaaga atttctactt cttccatgta atgtgttgta tagacaatgg
    54781 ttgctccttg tcgattcagc tccttgatac tttctaaaat tttattccga ctttgggggt
    54841 ctacagctac tgtcggctca tctaaaaaaa ttaaccgcgg cttgtgggca atcccacatg
    54901 cgatgttcaa ccgacgtttc aagccaccac taagttctcc tggacgaaac gaaacatatt
    54961 tttctaatcc cactaattga atcacctctt caatcaaggc tttccttttc tctttttcgg
    55021 aaacatataa accgcaaaaa taatcgatat tttcttgcac acttagttcg tcaaagaccg
    55081 caacgtcttg aggaacgacc ccaatcattg ccttgacagc ataattttca ggagtcattg
    55141 ttgtcccgaa caatttaatg gttcctttgt cataatttaa caaagaaagc atacagttga
    55201 tggcagtcga tttcccactg ccgtttggtc ctaacagacc taagacttct ccttcttgta
    55261 cttgcagatc aaaatgattc aatgctacaa aatctccata gcgtttgact aatttatcaa
    55321 tttcgataat catcatgaaa aactccttcc aaatttcttg ttgatctgac tataataaag
    55381 tgcaagaaaa gaaactagtg acgattggct aaaccacaca tgacatttgt cacaatgaag
    55441 gagtctgcta tgcataaatc tcggctactc aacgaaacta gctttctact ggttatctca
    55501 ttgcttttgc tggtaagtca aggattcgtt gctatgcaag ttatctattt attgatcgcc
    55561 gttttattca ctggtgtcag ttatttactg cctacaaagc caaattggat tttccaagtt
    55621 attctatttc ttttatgtgc ctttttacct gatcttgtcc tgtttctgcc agcgacgatg
    55681 cgagtgatcg cccctgaaga aagccacctt gattacttgt ttttgttagg ttttttgttg
    55741 atttcgacgg ttggtaatca tccccccatc aaggtcgcct ttgtcgtaat tttgctgttt
    55801 ttttcctttt acttacgaaa aaaagatcaa cgaacgaccg atcttgagaa aaagtacatt
    55861 gtctccaaag atactcattg ggaaaaacaa caagagttat cggaacaaaa taaagcattg
    55921 gccctgtcac aagaaacaca attagccttg caaattgtgg aagaacggaa ccgaattgcc
    55981 cgagacatcc atgacaatgt cggtcatctg ctgtcaagtg cgattttaca aattggtgcg
    56041 cttgaaatga tcaatcaaga accaaaacta aaagaaccat tagaaaattt aagtgccacc
    56101 gttcacactg ggatggatcg gattcgtcaa agtgtccatg acctccatga gacatcgatc
    56161 tcttttcaac actccttaga gtttctgatc gctgattttc cttcttctgt tacgattgaa
    56221 ggaaacttgt ttgaaggatt gaatgaaacg cagcaaaact gcttcttaat ggtcatcaaa
    56281 gaagccttaa ccaacagtat caaacatagt catgccaaaa ccgttgtttt acattttcga
    56341 acgttgccgg ccttttatcg cttgcaaatc acgaatgatg gcaccagccc acaaaaaaat
    56401 tctgctcccg gtattggttt gaaaacgatg cgtcaacgtg ttcaagaaca aaagggacaa
    56461 gtccatattt tccaagaaaa ccagcaattt cagttaacga tcattttacc aagggaggga
    56521 caccaatgat aacagtagtc attattgaga tgatccattt gtgacgaaat cgttacaaac
    56581 cattttagaa agcacgaaag agatccgtgt gttaggcatt ggtcattgtg ccaaggatgc
    56641 gctagtctta tacgaaaccc atcgtcccga tgttttgctg acggacatcc gcatgcctaa
    56701 acaaacgggc atcgatgctg ccaaagaaat tttggctaaa tttcccaaag ccatcctttt
    56761 gcttttgacg acattcaaag atgaagaata catccgcgaa gcattttcca tcggtgtcaa
    56821 agggtattta atcaaacaga acttgcaagc gattattcct tctgtcaaat ccgcttataa
    56881 tggacaggcc gtatttggta atgaaatcat cgagactttc actcaaatga tgaagaataa
    56941 accgacgatt gatagtcatg cttatgcttc ttttagtgaa cgtgagcttg caatcatcaa
    57001 agaagtagct gccgggaaaa acaataaaga aattgcagat gccttgtact tgagtgacgg
    57061 cactgttcgc aattacatca gccaattact agaaaagcta gatttacggg atcgcacgca
    57121 attggctatc tatttttatc agcatttgca ataagtctta tctaacacaa aaaaacctga
    57181 atgatgctcc ttcgcatcat tcaggttttt ttcacatctt ctattcaatt gtcccgcaaa
    57241 ccatttcctc acgattgaaa gaatcaagga ttcgcagggc tgccaggatt cgttggattg
    57301 ttcggcgtgt taggcggaaa aataggcgcc ttgtctaacg ttttttctag ttttgattct
    57361 tcacgatcgt ctcgttctac atcaggactt tcattcaatt tgaattcttt ttccatctca
    57421 tctaactttt taaagtcatt gccagattct tttgctaatt tcgctaattt atcttcggtt
    57481 tctttagcca taaagtaacg cccccctttt gatttcagct tagcatatca cactgaaaaa
    57541 acaaaagaaa acgctaacca acgatcattt ttagctattt ctcatcttta aaatcaagca
    57601 ttttttgccg gtataaaatc gtagggagaa ctgttttcca taccaatcat cggatctact
    57661 aactggttat cgatcacttc tgctgtaaga acgaaatctt tagaaacagc aggttctacc
    57721 tcttctttct tttcttctcc aacaaatgaa gaaaacagat ctggttccac tgtttccatt
    57781 acttggtttt tcgtttcatt cgtcccactg tcatcttcta caggtagctt ttcttttaca
    57841 acccgtggct cttttgtata gttcccatct tcaaatggat catttccgac caaagaatct
    57901 tcataagctg ctagtttggt ccggagagtg atattcattt tatcattatc catgatcctt
    57961 gatttcaacg tagtcatccg gcttgctgat tcattcgcta cacaagtgac ataggcttgc
    58021 tcttccccta acaaaatcaa cagttcctta ctgcgagtca ctgccgtgta gagcaaatta
    58081 cgctgaagca tccgctgata ttgatggacc atgggcaaaa taaccatctt gaattcactg
    58141 ccttgtgatt tatggattga gcaacaataa gaaagagtga ttttattcca ttcgtttctt
    58201 ttataagtga cctcatttgc atcaaactgg ataactaatt catccacttt atcttcagaa
    58261 tcttttgcca agatgatacc cgtgatttct cccatatctc cattgaatac attcaattcg
    58321 ggagtattga ctaattggag gactttgtct cctatccgat aaacggtgtc gttccaatgt
    58381 acttcctttt ttccaggttt ccctggattg aatatctcct gcatcatttt atttaacgca
    58441 tcgatccctg caggtccccg atacattggt gctaatactt ggatatcttg tgcacggaat
    58501 cccttatttt tcgctttttc cacaatttta gagatcaagg gttcaatttg ataagcatca
    58561 cttcggaaat aggaacgatc tttttgattc tttgtgaaat cttttggcag acgtccttct
    58621 ttgatctcat gggcaagagg aataatacta gaaccatcac cttgccgata aatctgattg
    58681 agttccattt tgggaatttg ttcgatttcc aaaagatcat ggagtacttg accaggaccg
    58741 acagagggaa gctgatcttt gtctcctact aagataactt gcatattcgt cggaatcgct
    58801 ttgaataatg tgttagccag ccatgtatcg accatagaca tctcatcaac aatcaaaagt
    58861 ccgccttcta attctttcgt actgactgaa ggtgtttttt cccgtccatt cagccccaga
    58921 agacgatgga tcgtactggc aggcagacct gtcgtttcgt tcattcgttt agctgctcgg
    58981 ccagttggtg ctgcaagtag aataggaaaa atttcttggg tatattttga aggatccaat
    59041 tccagtccgt tcaactctgc aaaaagattg acgattccgt tgatcacagt agttttcccc
    59101 gtacctggtc ctcctgttaa aataaataga ggggaacgga ttgcttcagc gatagcttgt
    59161 tcttgcgaag gtccatactg tatgccgaat attttttcga tacgccgaat attcttctgc
    59221 acttcttttt caggataatg gatttctttt ttacgactga gaaggcgctg gatcgaatta
    59281 ccgatccccc attcagaaaa gtacaaactg ttttcgtaaa gattagtctc ttcttgttgt
    59341 atctttcctt cttcaacaag ttggataatt acagtagcaa cctgatcagg ctggatttca
    59401 attgggcgac ttgtttctaa aatacggatc gtttgctgaa gcaatgtctc cgccggtacg
    59461 tatgtatctc ctgtttgaac tgcatgctga aaaatctgat gcaagatagc tgctcgaatt
    59521 cttctcggtg aatctgctgc aataccgatt tgttcggcta gattatctgc acgtttgaac
    59581 ccgattcctt ctatgtcttc gactagctgg tacggatttt cttcgatgat atccaaagac
    59641 tcgttcttat aggcctggta gatactgaaa gctaactgac taccgaaccc gtaacgattc
    59701 agtcccatga tcacttgatc catcccgtgg tttagccgaa tcgtctcagc aagcatttct
    59761 ctttttggct tcgtcaaacc ggagatttgt tttaataccg aaggatcagc aatgattttt
    59821 tcgatagcat cttctcccag caattctaca attttttctg ctgttttctt cccgattcct
    59881 gggaattttt cgctggaaag atacgctacg atcccatttg cagttgttgg cttttcttgc
    59941 tcatatcttt cgagtttaag ctgccttccg tatttaggat gatccactaa ttctccataa
    60001 aaacgataag tctcattttc ttgaatatcg ccgaaacttc cggtgactac aatctctttt
    60061 tcacggtaat cagctgtggt ttcactgatg tgtaccaaaa gcactttgta aaaattacta
    60121 ggattttgaa aaaaaatcgc ggcaactgta ccaacgaaat aaggcatttc ttctggctgc
    60181 atcggaagcc gcctccttct tctatagtaa aggttctggt gctgtttcag ttcctaaaaa
    60241 atctgtttgg ttccatactt tcagttcata tggcaataat ctgcaaggct cttcagtctc
    60301 taaaatcgtc aaactactat tgaacaatcc acccatttca cgcaactcac ttagctcttt
    60361 tcctgtcatc cattgaatgg ctgcagttaa agaagctcca tgtcctacga ataaaagtgg
    60421 gccatcttta tgttgggcaa ccgcatctgc tacaacagtt tcgatacgtg tgattgccga
    60481 ttcaatcgtt tctccgtgaa aaggagaagg atcatacaga tctaaatgat tacgcaaatt
    60541 cggcagatta tccggatatt tctggtacat ttcatcgatc gactgacctt ctaaagtacc
    60601 cagccctagt tctcttagct tatctgtata aaaaatctct accggacgag caagctcttt
    60661 gttgatacct tctgctgtat cacgtgctcg ctttgctgta ctggaataaa ttgctttaaa
    60721 aggaacatat tttacctttt tcccaaatgc tttgatttct tcgtaacttt gtggcaaaag
    60781 cggagaatcg ccattgctcc cttgaaaacg tctttcctga ttccattgtg tcttcccatg
    60841 tcgggtaaaa tatagttcca tacgcagcaa actcctgtct ttcttttatt ttactctata
    60901 ataaactgtc taatccagct tgtcattttc atagtgatgc gtcaattcta aattagggaa
    60961 tccttgctgg cgaagtgctt catacactat cattgcagct gtattcgata aattcaatga
    61021 gcggacatgc tcatcattca tagggatgcg taaacacttt tcttcgtttt cacgcataaa
    61081 tgtttctggc aaaccggttg tttcttttcc aaataaaaag aagtgctctt ctccatcagc
    61141 aaaattttcg tcactatata ctttatgggc aaattttgag atcaaatgta gtttacgatt
    61201 acctaaaaat gttaaaaaag cttctaaatt actgtggtaa gtaatattta catcattcca
    61261 ataatccaac cctgcccgtt ttagatgttt gtcatcagtt gaaaaaccta gtggctcgat
    61321 taaatgaagc ggagtattcg tggctgcaca cgtacgggca atatttccag tgtttgcagg
    61381 gattaatggt tcaaataaaa cgatatgatt catcaggatc attcctctca tatttatgtt
    61441 cgtttctatt ttctgacaat ttgatttttg cataaaaaaa aacgtatcaa ctcggtgtca
    61501 gtcactgcga gtcgttacgt tagtgaagct cttctcacta acttttatca gaacaggaac
    61561 ctgataaaaa ccaatgaaaa aacaacttgt tgctaatata acaccctcaa cttttttttg
    61621 caacctctac tcattaaaaa ctgctagaaa aacgttttct cttagttcct tttaataatt
    61681 ctatgtcaat tgtaatcttc ttcaaaggat tcttatataa gtctgctttg attcgctctt
    61741 ctacctgcca ttctaaaggt gacatggcca aaagatcttt ttgattttcc tctggtatct
    61801 caaattcata ggttacacgc tgacgttcag ttaatttcat tgcttcagca aacttggcta
    61861 ctacacgttc attggaataa ctctgttttt caggttgatt cggataaaaa gcctgacgta
    61921 gttcctttaa ataattttct tgtggcacca ccttcaacac ttctccatct tctgagagta
    61981 cacgttggaa ttcttggtaa tgagaaggcg aaaagatatt taaaaccgcg ttgaatgttt
    62041 gatcagcaaa cggcaaattg gtcaaatcag ctacacacca aaatgcttcg gcagattgtt
    62101 ctgtagctgc gtagactcct tcttttgaaa tatcaaatcc aacagcattt tgaatctttt
    62161 tcaattttga aagttcattc aagaagctac cttctccgca gccaacatct aatagcgaga
    62221 cttcttcagg taaatgctgc gcaatagtct caataacggg ctgatacatg ccagattgga
    62281 tcattctacg ccttggaacg aacattcctt gatcgtattc tgttttaacc gcatgggata
    62341 aaaaataaag tgttcctttt ttggaaaggt caaaacggtg attatttttg catatcaagc
    62401 cattatcaga cttttttact tcttcttggc aaaccggaca gcggaacagc tgatgatttt
    62461 ctgccaaaaa ctggcgtcct cggtcaattt tttttaacat agttccccct catttctgtt
    62521 ttatcttacc gttagatgct cactttggca actgctaaaa atatgataca atgcctagaa
    62581 gaaagtgaaa gataaaggag aagattagat gatcaaagaa ttttgcgctg aaaactacac
    62641 atctattcct ctagcaattg ctagaggagc cgatcggatc gaattgtgtg acaacttagc
    62701 ggtcggtggc acaaccccga gtactggtgt gatcgaagaa acgttaagtt atgctgggga
    62761 aaaagatatc cccgtaatga cgattattcg tcctagaggg ggcgacttcg tctataacga
    62821 tatcgaattg aaaatcatgc atactgattt gattgaagca aagaaattag ggacggatgg
    62881 cgtagtattt ggttgtctta ctccttcagg ctggctagac gaagaggcct tagaactatt
    62941 gatcgaaaca gcagaagggt tgcagatcac cttccatatg gcttttgaca gtattcctga
    63001 agatcggcaa ttcgaagcaa tcgattggct ggtagaacat ggtgttgacc gtatcttgac
    63061 tcatggcggt cctgctgaca aaactattgt agaaaatttc ccacggctta aagaattgat
    63121 tgcctataca gatggccgct taatcatttt gcctggtggt ggtgtcactg cagagaatgc
    63181 agcacatgta gctaaagaat tgaacgtaag cgaagtacac ggaaccaaaa tcgtggatct
    63241 tcagttataa tcttataaac aaaaaaacat ttgcaacagg cataatgctt attgcaaatg
    63301 tttttgtttt tttacataaa atagcccata aataaagaag caatattgaa ataaatcagt
    63361 acactcgtca aatcgctcaa agtcgtgata aagggaccgc ttgctactgc tggatcaaat
    63421 cctagacgat ccattagcat cgggattaaa ctacctgcaa gattcgccac tgtgattgca
    63481 aatagcatag ccatccctat gacaaacccc aagataaaat tatgtttcca aaaacctacg
    63541 attagaaaaa tcgtgatccc cgtaacagct cctgtgacaa cgccggtcaa gacttcagcc
    63601 aaaacaagtc gaacaaatcc atgatctttc tcatcagaaa tcgcaagtcg acgaacagcc
    63661 acagctagcg actgggttcc agcattaccg gcagttcctg taatcagcga aatgaagact
    63721 gctaaaatac tcgcttcact taccaagtct tcatagtgac tgattaaaga agcggtcgac
    63781 atacctaaaa acaacagagt gatcagccaa ggcaaacgtc gagacgctgc ctttactgga
    63841 ttttcattaa tttcttccac attgaccccg gcaagtcctg aataatcgct agcagcttca
    63901 tcatcaataa cgtcgatgat atcatcgact gtgacgattc ctaacaaatg atcatcataa
    63961 tcggtaacag gaagagctaa gaagtcataa tctctaaatg tttgtgccac atcttcttgg
    64021 tcgtcgccta catgaactga aagcactcgt tcgctcatca gatcagaaat cattgcgtcg
    64081 tcatcattca cgattaggtc gcgcagagaa ataaccccta ctagctgacc ttcttgatta
    64141 acgacataga tgtaatagat tgtttcagct acatctgctt cgttcttcag cacgtacatc
    64201 gcagagcgaa cagtttgatt ggctacgatc gaaacaaatt cagttgtcat gatcgcgcca
    64261 gccgtttcat cctcgtaatg gagaagttcc ttgatttcac tggcatcgtc tgccgacatc
    64321 aaacttaaat atttagcaat ttgcttttta tccagcgtat taagcaagtc aacagcatta
    64381 tctgtataca tctcagaaag catatcagct gcatagctag gacgcatttc atctaggtat
    64441 tctttcatat gttcgttgtc ttcttcaatc acatcgaaca tatccgctaa ttctttaggc
    64501 gacagatagg aatagatcag ctgcctgttc tcttctgtaa gagattggta gaattgcccc
    64561 tgctcataga tatgcatctc taaaaaactg tttctgaatg cctgaatatt attttccctt
    64621 aaatcttgag tcaactgggc aaatctttcc tctaattctt gattttcatc caaaccaatc
    64681 tcacctcgcc ttattcttca aaccgtctca caactgcctc catgtctgcg gctaaaggct
    64741 gcttgaactc cagcaactct tctgtaaatg gatggtaaaa acgcagatca taacaatgaa
    64801 gggcttgtct ttttattccc agatccattc gcccgccata catatcatca ccgagcaggg
    64861 cacagccaat tgcggaaaaa tgaactctta tttgatgtgt ccttcctgta tgcagctgga
    64921 tatcaactaa cgcgatttct gttagtcgct tctctatcca gtactcagtc tgtgccgaac
    64981 gtccttcatc agagaccatt cgcttcaata gcgaagaata atctcgggcg atcggcaaat
    65041 cgatatgtcc atgtgccgat aaatctgaaa gccttccact gactaaggcc tgatattttt
    65101 tcacaaactt cttttcacga agttgcatat ctaattttgc gtgcgcaaat ccatgctttg
    65161 caaaaagcat caaaccagat gtatcccgat ctagtcgcgt caccacatgg attacttggt
    65221 tttcgtaacc ttgtttttta taataagcct ttacacgatt agccattgtc ccatttggat
    65281 ggtattgggc aggaatagac gaaacgcctg ctggtttatt tactaccaga acgtgttcat
    65341 cttcatacac gatatcgatc ggtgtttcat ccaaaagtac ggtttcatgt tctccttcag
    65401 caggaatcac aatggttacc ttatcatcct tagctagaga aaacaagaca ttttctactt
    65461 gatcattaac tttgatttga ccgccttgaa attttatttt cgctaacaga ccctttgaga
    65521 tccctttttc ttttaaaaaa tattttactt gctgagaatg atctttctca taatcccatg
    65581 taaactgcat atcaatcctc actaataaag gcatctttca cacgatgcca aaaatgcata
    65641 tgtcgataag aagcaaaatg gatccgttct tctgctattc gataataaat tgagcggata
    65701 tttgcttttg cgacattcaa ttgatcaacc gttacaagat aatcttctgt attttccaat
    65761 tttatttcta gccattcatc atgggcaatc acgatcggag aacccaaagt acgaaacact
    65821 cgattattca gtgaagcaat ctctgccaac tgaaaggcat tgatactagg atggatcaca
    65881 gcaccgccga cacttttatt atatgctgtc gaaccagtag gcgtagaaat cgtcaatcca
    65941 tctcctctaa aactttcaaa cagctcgttt ttgatgtata catcggctac catcgtacga
    66001 ttggcccgtt taatcgttga ttcattcagt gctaaaaaat gctggtccgg tgtttcatcc
    66061 aaataactga tccgaacatc cagcaaggga taactaacac tttgttcccg gttcgttcgt
    66121 aagctgtcta ctagttcttc cagctcgtaa tcccgccaat ccgtgtaaaa ccctaaatga
    66181 cctgtatgca cgcccaagaa acgcacatca ttcagacaat gactgtagtg atggaacgcc
    66241 gacaataatg tgccgtctcc gccgactgag atgaccaatt ctggctcatg atcatctcgt
    66301 tgaatccctg cttgttctaa aagtgcgttc aaacgttctg tcacttctat agtctttgct
    66361 tctttattat gaacgatcgc tactttcatc ccctgcctcc tctctttcgc tttctttctt
    66421 caaaagcgtt cgatagtaga catcatctga ttttcctctt ccatgggaga ataaccgctg
    66481 tgcttcttgg atttcttcac ggatactgga catctcttca tccaactgat aggcagcttc
    66541 tgccgcacgc tgaagtcgtt cactcatttc ttctggaaaa acgccttgat atttataatt
    66601 cagcgaatgc tcaatcgttg cccagaaatt catcgcaaga gtccgaatct ggatttccgc
    66661 caaaattttc ttctcaccgc tgatcagctg tacaggatac tcgatcacca gatgataaga
    66721 acggtagcca cttgcttttt tatttgtgat gtaatctcgt tcttggagaa ctttcatgtc
    66781 ttttctttta cggatgatct caacaacttg atggatatct tctacaaact gacacatgat
    66841 ccttaacccg gcaatatcag acatttcttc ttctaaacgt cccattggaa tatgccgtaa
    66901 ttgtgatttt gttacaatac tatcgactgg cttgactctc ccagtgacaa attcaatcgg
    66961 gacatgtcga ttttgttcac ggaactgttt gcggatcccc cgcagtttca ctttcaattc
    67021 tgatacagtt tgttcatatg gtgctaaaaa tgcttcccaa tctcgttcca tagctgatac
    67081 ctctacttca ttaacattca ttgtttattc taccatatat gcaaagtttt ttcgtactct
    67141 tgatttatgc attgaccaaa aaaagaaaat taggcaaaat agacaaaaag gagtcgatca
    67201 aatgacacaa atgcttgaaa tcgaatataa atctatgctg acaaagcaag agtacgagat
    67261 attcatcgct cactatcaat taacagataa agatttccgt gtacagacta atatttattt
    67321 cgataccgtt gatgaacagc tgaagaaaca aaattgtggc ctacggatcc gtttcgttgg
    67381 tcatcaagct gaatatacat taaaaacacc tgctgaaaaa gggcgtctcg aaacaacgga
    67441 tacctttata acagaagaag cagaagcatt tatcttcgaa aaacgtctgc ctcgttcagg
    67501 cgcagttttt caaaaacttt ctgatttgaa tatcgatcct gcttcattaa tccaaaccgg
    67561 aaagcttaca acaaaacggg ctgaattccc tattgaagaa ggacttttag ctattgatga
    67621 aagctgggga gacaatctac acgattttga actggaacta gaggtaaggg gatgcatctg
    67681 tgggaaaaat tgcttttata aattttttaa aacgtttttc tttaccttat cgtcctgcta
    67741 agaacaagat ccaacgtatg cttgaagcta aaaattagaa acctttcatt ttcacaaggc
    67801 acttgagttc atttttttac ttttttctgt taagttatag gatgtgaaag aatctagtca
    67861 ctagttgtat agaatctatt ttgggggaga ttcatatgat cgaaatctat ttatttgtta
    67921 atcctttagg ggaatactgt ttcgaaatgg aacaacagtt attacaattt atcgaagaag
    67981 agtacgggac accatcaaaa gaaaagatgc aatttcgctt tcttcctttg gtcaatttgc
    68041 agacaattgg ggatgtcatg caacaaaaag gaatttctca gaacaatctt gaggaacgta
    68101 atcacttatt ctcaatgact tattctgcag cattggactg caaagcggcg cagtttcaag
    68161 gaaagaaaaa aggccgccgt tttttgatca aattgcaaga agcagtcggc tgtaatgaca
    68221 taccatattc tcaagaactt gctgaatcca tatttgaaga aatcggcggc gatttgaata
    68281 tgtttaaaga agatcgtcag tctgacttcg ttaaagaagt attcttttct gatcaaaaaa
    68341 ttgctcggga aatgggcatc acaaaacacc cttctgcagt cgtttacaat tatgcctgcg
    68401 accgtgattt tggtgtttta gtagaagtaa aaggtacaag tagcctttgg agaatcacag
    68461 agctgtgtaa aacaacagat aactcatatc aagtttttaa tggtgaacat ttacatacaa
    68521 atgattctca gttccattca agaactagcc atttacactt gctttctaat taaaaaaata
    68581 cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga gaaaatcaaa
    68641 aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg ttgttcaaac
    68701 atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc ttttttcatt
    68761 acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt ctctagtgcc
    68821 tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa gccagtcgag
    68881 tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc gaatttaatt
    68941 tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc ataactatca
    69001 cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat gaaatgctcg
    69061 aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa gtaatggttg
    69121 agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc cgttaggata
    69181 ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc gtacacataa
    69241 ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg gacaagcgta
    69301 aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt gtcatagctt
    69361 cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat ccaacgttca
    69421 gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag tgcttctaaa
    69481 gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa gaccggtgta
    69541 taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa ttccatgtat
    69601 cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta tacactttca
    69661 ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg gactttcgct
    69721 ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt tctaaattgt
    69781 tcgtaaacac tgtacaatcc cttaaatgct gcttcgcgca cccttcgatc cgtgctttct
    69841 agcaactgac catacacgcc atgagataat tggactattt caccattttc tccttcaatc
    69901 gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga agcatcaaag
    69961 atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg ggctcgatta
    70021 tctactattt gctggatata atggcgatag acttccaatt ttggttcttc tttgaaatat
    70081 tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga aacggcttca
    70141 ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc tgtatttcca
    70201 gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg gcgataaacc
    70261 ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag tgttcctttg
    70321 tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc aaactcttgg
    70381 tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc ttctcgtttt
    70441 ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct atctatcaaa
    70501 atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc attcatgtgt
    70561 ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc gattcctagc
    70621 ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt taaaaaactg
    70681 ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat gttcttttat
    70741 ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt cttcgtacaa
    70801 cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt tttgatagat
    70861 ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt gtatggatac
    70921 tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat cttcactcac
    70981 tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata tttctttaag
    71041 gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg atacagtctc
    71101 tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc agcaatgcac
    71161 tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt gcgattgtcc
    71221 aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat aattttgggt
    71281 tctttcaata aatctctggt gagacagtct agaacattgg atttctattg ctagattcgc
    71341 caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa atactggttc
    71401 tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct cttttgattc
    71461 tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag cacatttttt
    71521 ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt tctttccttt
    71581 ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca gcatttttct
    71641 ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg cgtgaaaaag
    71701 ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata tttttcgttt
    71761 ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa aaaagactgc
    71821 gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat aaaatttcgt
    71881 tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg tttctggtgt
    71941 acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta catccgcttg
    72001 gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga ataaatacaa
    72061 atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt gttcaaaatc
    72121 ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag ataattcttc
    72181 ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt ctgaatcaac
    72241 agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga taaacagttc
    72301 taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc ggaactcctc
    72361 ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt tgtgattgcc
    72421 aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa ttagtacacg
    72481 gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt tgccacaatg
    72541 tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa atctcgctgt
    72601 taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt atttaactat
    72661 aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc cctctctatt
    72721 tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa tactttttgt
    72781 aaaaacaaaa aaacttggaa aaactatct
//
LOCUS       DADQCX010000003        59057 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.003, whole genome shotgun sequence.
ACCESSION   DADQCX010000003 DADQCX010000000
VERSION     DADQCX010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.003"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(134..262)
                     /locus_tag="J8R83_000142"
     CDS             complement(134..262)
                     /locus_tag="J8R83_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAZ9573311.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(265..1638)
                     /gene="rlmD"
                     /locus_tag="J8R83_000143"
     CDS             complement(265..1638)
                     /gene="rlmD"
                     /locus_tag="J8R83_000143"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAZ9573312.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1749..2804)
                     /locus_tag="J8R83_000144"
     CDS             complement(1749..2804)
                     /locus_tag="J8R83_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAZ9573313.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2814..4244)
                     /gene="gatB"
                     /locus_tag="J8R83_000145"
     CDS             complement(2814..4244)
                     /gene="gatB"
                     /locus_tag="J8R83_000145"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAZ9573314.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4241..5713)
                     /gene="gatA"
                     /locus_tag="J8R83_000146"
     CDS             complement(4241..5713)
                     /gene="gatA"
                     /locus_tag="J8R83_000146"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAZ9573315.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5713..6018)
                     /gene="gatC"
                     /locus_tag="J8R83_000147"
     CDS             complement(5713..6018)
                     /gene="gatC"
                     /locus_tag="J8R83_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAZ9573316.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6124..8160)
                     /gene="ligA"
                     /locus_tag="J8R83_000148"
     CDS             complement(6124..8160)
                     /gene="ligA"
                     /locus_tag="J8R83_000148"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAZ9573317.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8177..10411)
                     /gene="pcrA"
                     /locus_tag="J8R83_000149"
     CDS             complement(8177..10411)
                     /gene="pcrA"
                     /locus_tag="J8R83_000149"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAZ9573318.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10566..12125
                     /locus_tag="J8R83_000150"
     CDS             10566..12125
                     /locus_tag="J8R83_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAZ9573319.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12236..14167)
                     /locus_tag="J8R83_000151"
     CDS             complement(12236..14167)
                     /locus_tag="J8R83_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAZ9573320.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14185..15099)
                     /gene="pfkB"
                     /locus_tag="J8R83_000152"
     CDS             complement(14185..15099)
                     /gene="pfkB"
                     /locus_tag="J8R83_000152"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAZ9573321.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15096..15848)
                     /locus_tag="J8R83_000153"
     CDS             complement(15096..15848)
                     /locus_tag="J8R83_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9573322.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(16007..16216)
                     /locus_tag="J8R83_000154"
     CDS             complement(16007..16216)
                     /locus_tag="J8R83_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573323.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16227..17555)
                     /locus_tag="J8R83_000155"
     CDS             complement(16227..17555)
                     /locus_tag="J8R83_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573324.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17920..18507)
                     /locus_tag="J8R83_000156"
     CDS             complement(17920..18507)
                     /locus_tag="J8R83_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAZ9573325.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18590..19840)
                     /gene="clpX"
                     /locus_tag="J8R83_000157"
     CDS             complement(18590..19840)
                     /gene="clpX"
                     /locus_tag="J8R83_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAZ9573326.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20087..21376)
                     /locus_tag="J8R83_000158"
     CDS             complement(20087..21376)
                     /locus_tag="J8R83_000158"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAZ9573327.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21530..22462)
                     /locus_tag="J8R83_000159"
     CDS             complement(21530..22462)
                     /locus_tag="J8R83_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573328.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22619..23278)
                     /locus_tag="J8R83_000160"
     CDS             complement(22619..23278)
                     /locus_tag="J8R83_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAZ9573329.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23281..24306)
                     /gene="sppA"
                     /locus_tag="J8R83_000161"
     CDS             complement(23281..24306)
                     /gene="sppA"
                     /locus_tag="J8R83_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAZ9573330.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24319..24609)
                     /locus_tag="J8R83_000162"
     CDS             complement(24319..24609)
                     /locus_tag="J8R83_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573331.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            25019..26824
                     /gene="glmS"
                     /locus_tag="J8R83_000163"
     CDS             25019..26824
                     /gene="glmS"
                     /locus_tag="J8R83_000163"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAZ9573332.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26896..28251)
                     /locus_tag="J8R83_000164"
     CDS             complement(26896..28251)
                     /locus_tag="J8R83_000164"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAZ9573333.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28275..29444)
                     /locus_tag="J8R83_000165"
     CDS             complement(28275..29444)
                     /locus_tag="J8R83_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573334.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29441..30328)
                     /locus_tag="J8R83_000166"
     CDS             complement(29441..30328)
                     /locus_tag="J8R83_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAZ9573335.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30517..34197)
                     /gene="nifJ"
                     /locus_tag="J8R83_000167"
     CDS             complement(30517..34197)
                     /gene="nifJ"
                     /locus_tag="J8R83_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAZ9573336.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34395..34916
                     /locus_tag="J8R83_000168"
     CDS             34395..34916
                     /locus_tag="J8R83_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAZ9573337.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35615..36180)
                     /locus_tag="J8R83_000169"
                     /pseudo
     CDS             complement(35615..36180)
                     /locus_tag="J8R83_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36359..37015)
                     /locus_tag="J8R83_000170"
     CDS             complement(36359..37015)
                     /locus_tag="J8R83_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573338.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37583..38518)
                     /gene="whiA"
                     /locus_tag="J8R83_000171"
     CDS             complement(37583..38518)
                     /gene="whiA"
                     /locus_tag="J8R83_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAZ9573339.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38552..39550)
                     /locus_tag="J8R83_000172"
     CDS             complement(38552..39550)
                     /locus_tag="J8R83_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAZ9573340.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39547..40431)
                     /gene="rapZ"
                     /locus_tag="J8R83_000173"
     CDS             complement(39547..40431)
                     /gene="rapZ"
                     /locus_tag="J8R83_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAZ9573341.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40566..41297)
                     /locus_tag="J8R83_000174"
     CDS             complement(40566..41297)
                     /locus_tag="J8R83_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAZ9573342.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41301..42566)
                     /locus_tag="J8R83_000175"
     CDS             complement(41301..42566)
                     /locus_tag="J8R83_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAZ9573343.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42829..45645)
                     /gene="uvrA"
                     /locus_tag="J8R83_000176"
     CDS             complement(42829..45645)
                     /gene="uvrA"
                     /locus_tag="J8R83_000176"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAZ9573344.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45655..47649)
                     /gene="uvrB"
                     /locus_tag="J8R83_000177"
     CDS             complement(45655..47649)
                     /gene="uvrB"
                     /locus_tag="J8R83_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAZ9573345.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47908..49410
                     /locus_tag="J8R83_000178"
     CDS             47908..49410
                     /locus_tag="J8R83_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9573346.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49412..50149
                     /locus_tag="J8R83_000179"
     CDS             49412..50149
                     /locus_tag="J8R83_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573347.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50517..51683)
                     /gene="dnaJ"
                     /locus_tag="J8R83_000180"
     CDS             complement(50517..51683)
                     /gene="dnaJ"
                     /locus_tag="J8R83_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAZ9573348.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51834..53663)
                     /gene="dnaK"
                     /locus_tag="J8R83_000181"
     CDS             complement(51834..53663)
                     /gene="dnaK"
                     /locus_tag="J8R83_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAZ9573349.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53714..54277)
                     /gene="grpE"
                     /locus_tag="J8R83_000182"
     CDS             complement(53714..54277)
                     /gene="grpE"
                     /locus_tag="J8R83_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAZ9573350.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54371..55414)
                     /gene="hrcA"
                     /locus_tag="J8R83_000183"
     CDS             complement(54371..55414)
                     /gene="hrcA"
                     /locus_tag="J8R83_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAZ9573351.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55649..56815)
                     /locus_tag="J8R83_000184"
     CDS             complement(55649..56815)
                     /locus_tag="J8R83_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAZ9573352.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGNRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56831..57058)
                     /locus_tag="J8R83_000185"
     CDS             complement(56831..57058)
                     /locus_tag="J8R83_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAZ9573353.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57445..57701)
                     /locus_tag="J8R83_000186"
                     /pseudo
     CDS             complement(57445..57701)
                     /locus_tag="J8R83_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(58044..58509)
                     /locus_tag="J8R83_000187"
                     /pseudo
     CDS             complement(58044..58509)
                     /locus_tag="J8R83_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
BASE COUNT        16263 a        12810 c        10278 g        19706 t
ORIGIN      
        1 tgagccagaa tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta
       61 ttgacaaaga gccactaaaa agactaagaa acaataacaa aagttaacac ttcttagtct
      121 ttctttagca cgtctattta ttaaagattt tagggccttt tctcatgttt ttacgatcat
      181 tcttaggtgt ttccatttgt ttggatcggc ctccaccttg tttctttttg atcaattctt
      241 tcattttttc tttttggtcc atttttattc tcctttaacg aatgaagcga ctaattcgat
      301 atgatgggtt tgcgggaaaa gatctacagg ctgaactttc ttcacggcat aacctgcttc
      361 tgcaaataac ttagcatctc ttgcaaaagt tgccggatta catgagatat agacgattcg
      421 ttctggtgac atttcgattg ctgattcaat aaaatgatga tctaatcctt ttcgtggagg
      481 gtcaactacg atcacagatg gtttgatccc tttttcttgc cattttttca taactttttc
      541 tgcttttccg acttcataat gaacattttc gattttatta tttaaagcat tgaactgtgc
      601 atcttcaatt gcttctggaa taacttccat cccatacacc ttatccactc tgtctgctaa
      661 agacaagcca atcgtaccta ttcctgaata agcgtcgatc acaatgtctt ttttatctaa
      721 ctcggcaaac tcgatggctg tttggtacag atactctgct tgttgagtat ttacttgata
      781 aaatgacttt gctgagattc gataggtttt tcctaatagc tgatcttcga tatagtctct
      841 gccatataaa actttttctt tgtctcctaa aatcacattt gttttttctt cattgatatt
      901 ttggatgacc gaaaccactt ctggcaattc ttcatgaata gcttcagcaa tttccttgga
      961 tttaaagaat ttttctttac gagtaactaa aacgaccatc atttcatggg aataatgacc
     1021 acgacggata atgatgtgac gaagctgtcc ttcatttttt tcttcattat atcctcgtac
     1081 ttggaaccgt tgcaagatat ctctgactac tttgattgct tgatcgatga caggatcttg
     1141 gatataaaaa tcttcgatag ggactagatc atggctattc tttttgtaaa aaccggtggc
     1201 taactgtcca tcgatacggc gaacagggat ctgtgcttta ttacggtagc cgaatggttc
     1261 tgccattccg accgttggaa gtacaggaac ttctggcatc ttagcaatct tcgccattac
     1321 atgctctact tgtttttgtt tgaagacaag ctgttgttca tacttcaaat gggctaaagg
     1381 tgcgatacct atgcgaagta atgcattgtt ttctacaggc tgacgatcag gtgattgtgt
     1441 aataaatgtt tcgacttttc catatccaaa cttattgcct gcttttacta ctagtatttc
     1501 tacttcttct ccagggagtg cattttcgat aaataatgga taaccatcga tttttgctac
     1561 ccccattcct tcataactca agtcgacgat ttcgactgta tatcgttcgt ttttctttac
     1621 tatttgctgt tctgtcatat tttgctcctt taagcctatt tttcaatcct actgaactct
     1681 actataaatc agctaattac acaactaaaa ccggcactga ccttactacg ttcagcaccg
     1741 gcttttgatt aattcttttg attaggtgtt tcgtctgcta tttttccgtc accgtcgata
     1801 tcttcatccg ttaaacgttc gacttctttt acgaattctt tgctgacaac ctctaattct
     1861 tcttcatctg tacctgtgat tgcttcatca ggaatctgat cggtattggc aaagaactca
     1921 atgtgttgat gaagattttg gaaatgcatc ggtgcttccc cgccgtattc accatctaag
     1981 ttgatcatta ctggtcgatt gatatcatct tctgtttcaa cgaacaaact gcttgttttg
     2041 gtatagatta ttcttggatc atcgacatgt cgaccgccat tcagcatgag tgctgcaata
     2101 tgcaagatct caaagatatt tgctgtcttc acaatgatta aagaaaactt cccatcatcc
     2161 aatttggcat ctggcgcgat ctgttcgaat cctccaacag agttcgtcag ccctaggaaa
     2221 aacatcgaag catttccgat atattcccct tcatcatact tcaagcgcat tttgattggc
     2281 tttactcgag ggagcatctc tgctcctttc gcaagataag caagataacc aaaaatactc
     2341 tttagttctg atggaacttc ataagtcaat tctgtcaaat agccacctgc agcgatattg
     2401 atgaagtaac tgttatcaga aaggccgatg tccattttta cggtttggtg tttttttatc
     2461 acttctgctg ctgctttaat attatctcta ggaattttta atgctcgagc atagtcgttc
     2521 gttgtaccag ctgggatgat ggccatttta ggacggtgtt caagcggagc gattccatta
     2581 accacttcgt tgattgtgcc atcgccacca gctgccacta ctagatcaaa acctagttct
     2641 gcgactctac atgcttcatt cttggctgaa tctggttctg gtgtagttgc ataggcgctg
     2701 gcttcaaatc ctgcttcttc taatgcctgt aggatatccg ccaaattttt tttcaataat
     2761 tcttttcccg aggtggggtt ataaattacg cgtgcttttt tcattttcag cctctatcgt
     2821 ttcgctaatt catctttaag tagcttattc acgacaccag gatttgcttg tcctttagtt
     2881 gctttcatga tttgaccgac taggaagcca accgcacgat cttttccatt tttgaaatca
     2941 tcgacagatt gttggttgtt atccaaaatt tcattaatga ttggcagtag tttgttcgga
     3001 tcagataatt gcacccaacc atttttttca actacttctt gggcttctcc gccatttgtg
     3061 atcaattcac ggaagacttt tttggcgatt tttgagctga tcgttccatc ggcgatcaaa
     3121 cgaatcattc ctgctaagtt ctcaggtgtc aattttgtct cagctaattc cagtttctca
     3181 ctgttcaagt aagcagaaac ttcacccatc aaccagttag atgcttgctt ggcatctgca
     3241 ccattttcca aaacagcttc aaaaaaatca gacatttctt ttgtaagtgt caataccatt
     3301 gcgtcatact ctggaagtcc aaactcacgg atatagcgtt cgcgacgaga agctggcatc
     3361 tcaggcaaac tagcttttac tttttgaatc cattcgtcat cgatcacgaa tttcgggata
     3421 tcaggctctg ggaagtaacg ataatcacta gacccttctt tgacacgcat caaaactgtt
     3481 ttattcgttg tttcgtcaaa acggcgtgtt tcttgttgga tttctcctcc tgaaagaaga
     3541 acttttgctt gacgtttttc ttcaaaagct aaaccttttt tcacgaaaga taaagagttc
     3601 aagtttttca attctgcttt cgtaccgaac tcttcttgtc cataagggcg aagagaaata
     3661 ttggcatcac agcgcataga gccttcttcc attttcacat cgctgacttc tgtaaattgg
     3721 ataattgatc gcaatgcttc tagataagcg tatgcttctt ctggtgaacg catatcagct
     3781 tcagaaacga tttcgatcaa aggcgtgcct tgtcggttca aatcaacgta agaataaccg
     3841 ccaataccat gcatgttttt tccagcatct tcttctaaat ggacacgttc gatccggatt
     3901 tttttctttt taccttctac ttcgatttcg atccatccgt catgaccgat tggttgatca
     3961 aattgggaaa tttgatatgc ttttggatta tctgggtaaa agtaattttt ccggtcaaaa
     4021 tgagtatctt tagagatttc acagtttaat gccaaagctg ctttcatccc gaattccagc
     4081 gcagctttat tcattactgg cagcacgcct ggataacccc agtcgatcac gtttgtattg
     4141 ctgtttggtt ctgcaccaaa atgagctggc gctggagaga aaatttttga gttggttttt
     4201 aactcgacgt ggacttctag tccaatgact gtttcaaaat tcattcgtct ttccctccta
     4261 aaatagctgg ttgttgttta tggaattctg ttgcttgttc aaacgcatat gccgcttgat
     4321 acatcgtttt ttcatcaaaa taattaccga tgatctgcaa tccaactggt aatccttctg
     4381 ataaacctgc cggtacagac atacctggaa gtccagccaa gttgacaggg atcgttaaga
     4441 tgtcactcat gtacattgtg attggatcgt taatgttctc accgattccg aatgcaactg
     4501 ttggtgaaga tggcccgatg atcaagtcat aatctgcaaa gactttttca aaatctcgtt
     4561 tgatcaatgt acggacttgt cccgcttttt tgaagtaagc gtcataataa ccagcactta
     4621 aggagaatgt acctaacatg atacggcgtt ttacttcttc accgaatcct tctgaacgtg
     4681 agttgacata tacatcatct aatgatttca cattttctga gcgataaccg tagcggatac
     4741 catcgaatcg ttgcaagttg gaacttgctt ctgatgaggc aatgatataa taaacagcca
     4801 caccgtattt tgaatgaggc aagctgactt cttccacaac agcacctaat gaacggaatg
     4861 tttctgctgc tttcaataca gcttctttta cgccaggggc cacaccttcg cctaagtatt
     4921 ctttaggtaa agcaatcttc attcctttga tgtcgcctgt cagtccctct gcaaaatcag
     4981 gaactgaaac gcctgaagaa gtaccgtctt tttcgtcata accgctgata gctgtcaatg
     5041 ctaatgcatt atctttcacc gtacgggtca ttggtccgat ttggtcaaga gatgaagcaa
     5101 aggcaatcaa accaaaacgt gagacacggc cataagtagg tttcatccct acgatgccgt
     5161 taaaagctgc tggttggcgg atacttcccc cagtatcact acctaaagaa actggaattt
     5221 gtccagctgc aactgctgct gcagaaccac cagaagagcc accaggtact tttgttgggt
     5281 cccaagcatt ttttgttttc ttgaaataag aagtttctgt acttccaccc atagcaaatt
     5341 catccatgtt tagcttacca acagggatca tatctgcttg atagatttta tccatgaccg
     5401 ttgcatcata aattggttca aaattgtaaa ggatcttaga tgcagcggtt gtcaagatat
     5461 cttttgttac gatattatcc ttgataccaa ttggaatacc agcaaggacg ttgctttcat
     5521 caatcccttt ttcatctaaa gcttttgcct gttccaatgc tttttcttcg ttcaatgtaa
     5581 tgaatgcttc gacctcaggc tctgtttctt tgattcgttc aaatgttgct tttgtcaaat
     5641 cttgtacagt gatttctttc gatacaagca tatgatgcag ttcttctaga gaacgattgt
     5701 gtaattctgt cattatgcgc cagcctcccc attatcgatg attgcgggta ctttgataaa
     5761 gccgtcttct gtttccggca catttttcaa taattcatcg cggttccatc cagcttgcgc
     5821 ccgatcttgt cgcatcacgt ttactgtttc aaccacattc gacgtaaatg gaacaccttc
     5881 tgtatctact tcttccagca tttcaaccat atcgatgatt ttacctaatt ggtcggtaaa
     5941 acttgcaagt tcttcatctg cgaacgcaag ttttgctaat ttggcaacgt gtttcacttg
     6001 ttcttcacta atcgccatac taccccttct ttctaaacga gttaaaaact ttgctctcta
     6061 ttttaacaca agagtgccgt gtctgaaatt gtttattgaa atttgtctga aaaaactcat
     6121 ttttcattct tctactgagc gacttttagc caatgcatct gccatttgat cttctgtcca
     6181 aacttcgatt cctaattctt gtgctttggt cagcttgctg ccagcatctt ctcctgctac
     6241 cacgatatcc gtttttttcg atacgctacc agtcactttc ccgccaagat tttcgatcgt
     6301 ctcttttgct tcttcacgag taaatcgtgt tagtttacca gtaaggacta ctgttttttc
     6361 tttaaaagga gactcgactt cttgcaattg ggcatttcga agccctttgt attcgaaatt
     6421 gacgcctgct tgttttaatt cattcatcaa ttcatggact tcttcgttac tgaaataagt
     6481 gactacactg tcggcaatga tatcaccgat cgtatcaagc gcaataatcg actcatagtc
     6541 acttttactc aatgtttcta gatcaccgaa atgttctgct aaaatttttg ctgctttcgc
     6601 tccgacatgt cggattccta acccgaaaat caaccgctcg accgaattat ctttgctgtt
     6661 gtcgattgct gtcaaaatat tatttgctga tttttctttt attttgtcca acgtcaataa
     6721 ctcttcttct gtcaatttgt aaagatcagc aacatctgct actagttttt tatcatacat
     6781 ctgttctagt acgcgcggcc ccaacccatc gatattcatc gcatttcttg aaacaaagtg
     6841 gttcaaacct tctttcattt gagcagggca tttaggattg atgcaccgta aggctacttc
     6901 ttcatccaaa tggacaagtt cacttccaca aactggacaa tgtgtaggca attggtattc
     6961 ttcgctgtct ttaggtcgtt tatctaacac gacttgcgaa acttctggga tgatgtctcc
     7021 cgctttataa atcagaactg tatctttcaa gcggatatcc ttcaacttaa tataatcacc
     7081 gttatgcagg ctggcacggc ttactgtcgt tcctgctact cggactggtg tcatgatagc
     7141 tgttggcgtt actacccctg ttcgaccgac tgtccattcg atgttttcga ttagcgtttc
     7201 aacttcttct ggcggaaact tgtaagctgc tgcccatctc ggtgctttga cagtaaaacc
     7261 aagttgatct tgtagcgaga attcattcac tttgatgacg attccatcga tttcataggg
     7321 caaatccaca cgtttgtcat gatattcttc aatgtatgac cacacttcat caatcgaatg
     7381 acatagacgt ttttcccgat tcgtgtggaa tccaattttt tctagctctt ctagcgcatc
     7441 atactgggtt tttgcttgca taggaccgaa atcagctact gtgtataaaa aagtgtccag
     7501 atttcttttc gctgtgattt tagaatctaa ctgacgcaaa gaaccagctg cggcgttccg
     7561 aggattcgca aagatatctt ttccctctgc ttctctgtct tggttcaatt ggacaaatga
     7621 ccgttttggc atgaaacatt cgcctcttac ttcgatgttc attggttctt ttaatttgat
     7681 tgggaccgac cggacagttt ttaggttttc agtgatgttt tctcctacag ttccatcccc
     7741 gcgagtcgca cctctcacga aatttccatc ttcataacgc aaagaaacgg aaagtccatc
     7801 tatttttagt tcacagcaat agtcaactac acgtcccact gctttttgta cacgttgatc
     7861 aaaagctatc agctcttctt tgctgaaaac gtcgttcaaa ctgtaaagcg gaatatcatg
     7921 agtgactttt tcaaaacctt ctaatacttt tccgcctact cgttgagtgg gagaatcaga
     7981 cgtgatcaaa tcaggatatt gttcctcaat tgctactaat tctgcgtatt ctttatcata
     8041 aacatagtct tccactgttg gtttatcttc tacgtagtat tcgcgagacc attggttcag
     8101 tcttgtacga agttcttctg ctcgtttagc agcttcgtca atcgtcattt catgttccat
     8161 catttaccct ccactactaa gctttttcaa ttggcgcaaa ggcagccaaa agacgtttta
     8221 ctccttgact tgggaaagcc acatctagtt ctagatcctt cgacgtcccg cttactcgga
     8281 cgactgttcc tagaccccat tttttgtgtt tgactttatc tccaggtttc cagctgttat
     8341 tttcccctcc agtagcactt ttagagggaa caaccgctgt ctctggctgt ttatagctat
     8401 atgctgtttt tttagcgaat acaggtgttt ttttaggcgt aggacgcatg ccttcgattt
     8461 ccagtaactc ctgatcgatt tcttctacaa aacgagaagg tcggttatat tgcgtccgtc
     8521 catataatgt tctggagaaa gcatttgtta aatacaacgc ttcttctgct cgcgtgatcc
     8581 ccacatatgc gagacggcgt tcttcttcca gttcgctttc ttccatcaat gctcgagata
     8641 aaggaaaaac cccctcttct agaccaatca ggaatacaac tgggaattct aatcctttgg
     8701 ctgcatgcaa agtcatcaat gtcacttggg aagcatcttc ttctaaattg tcaatatcgg
     8761 aaacaagtgc cagatcattt aagaagaccg ttagtttttc ttctggtgca tcagcgtctt
     8821 cttcattttg ctgttcgaat tgtttgtcga attcttgtgt gaccgttaaa aattcctcca
     8881 agttttcgat gcgtgcttgt gcttctaatg tattttggat ttttaagtct tctagatatc
     8941 cgctacgatc caaaacctct ttcgtcaatt ctgtcactgt caagtatggg atcatctgag
     9001 tgacttcttg gatcatctct ccaaatgcac ctaattgctg tcctgctttt ccaccgatat
     9061 ttgccagatc cacattttgc gctgcttcaa gcagtggcca ttcatgaaga gaagcaaaac
     9121 tgcgtagttt ttcgatagat cctggtccga tgcctcgttt gggcgaatta acgatacgct
     9181 caaaactgat tgaatcttga ggatttgcca gcacattcaa atacgctaaa atatctttga
     9241 tttctttacg atcgtagaac ttgtgccctc caaccatttt ataaggaata tttgctttca
     9301 acagagtttc ttccattaca cgagattgtg cgttcgtccg gtacaagatg gcaaagtcgc
     9361 cgtaattccg atgattgctt cgaatctctt cttgcatccg atctacgata aaacgggttt
     9421 cgtctcgttc attatctgca cggtagtaag tgatcttgtt tccttctttg ttttctgtcc
     9481 acaagttttt tggttttcga ttgctattgt tttcaatgac ttggtttgct gcgctaagga
     9541 tgtttttcgt ggagcgatag ttttgttcta gcaaaattac tgcagcatct ggataatctt
     9601 tttcaaaatc caagatgttc tgcatatctg caccgcgcca gccgtaaata ctttgatctg
     9661 catctcccac gacgcacagg ttcctaaatc tacctgccaa taaattgact agcgtatact
     9721 gtgcgtgatt tgtatcttgg tactcatcta catgaatata atggaatttg ttttgataat
     9781 atgtgagtga atcaggatgt tcttcaaata atcgaatcgt attcatgatc aggtcgtcaa
     9841 agtccataca ttgattatat tgaagctctt tttggtaagc agcataacat tttgccgcaa
     9901 tctcttcgta ataactgcct tgcatttttg caaaatcctg aggggtctgc aggctgtttt
     9961 ttgcttgaga gattgttcct aatatacttc gaggatcata ttttttcgga tcaatgttca
    10021 gttcttttag tatccgtttc atcaaggtca gctgttcaga agaatcgatg attgtaaagt
    10081 tccggttata cccgataaaa tcaacatctc ttcttaaaat acgcacacac atcgagtgaa
    10141 aagtcgatac ccagacatct tcgcctccag atgcgagaat cgcattgaca cgttctttca
    10201 tttcttttgc agccttattg gtaaaagtaa tcgctaggat gttccaagga ttgacttctt
    10261 tttcctcaat caaataggca atgcggtgtg tcagcactct cgtctttcca cttcctgcac
    10321 ctgccattag cagtaatggt ccgtcagtgt gaagaacagc ttctttctga cgggggttca
    10381 tcccgtttaa taattcagct ttggatgaca ttaacaacat cctttctttt atcaatcttg
    10441 ttaattatag cattttcttg gctttcatta aactagctag ttcaaaatca tttgtttctt
    10501 tttatggatt tttccttgtc aattcgttga tttcgcgcta aattaaaaga aagcgaggcg
    10561 tttgaatgga aaaaaaagga aaaatcaaga aattagataa gactcagata tattttattc
    10621 taaaaggaat atttgttgga ctgctgacag gaatcgtcgt tagcctgttt cgattatcta
    10681 tcgaaaagct aagcgattta gttcgaagta tctatgaaat gagtcgggaa cagccgattt
    10741 acttaattgg cctagctatt tgctgcatcc ttgcagcatt tttcgtgggt tatctggtca
    10801 aaaatgaacc ggatatcaag ggaagcggga ttccacaagt agagggacag cttcgcgggg
    10861 aattatcaat gaactggttc tctgttttat ggaaaaagtt cattggcggt gtactttcag
    10921 ttggtgcggg cctttttcta ggtagagaag gaccttctat acagcttggc gcatccattg
    10981 gacaaggagc tggacaattg tttcggagtc catcttcaga agaaaagatt ttaatttcta
    11041 gcggtgcaag tagcggactt gcagcagcat tcaatgctcc tatcgcagga ttactctttg
    11101 ttttagaaga aatccatcac tccttttctc cacttgtttg gctgacatca tttgcttcag
    11161 caatcactgc taacttcgtc tctctttact ttttcggctt gagacctgtt ttatatctag
    11221 gtgaccttcc ttctttgccg ttgaaatatt atggttcctt agtgatctta ggagtacttc
    11281 taggcatctt aggttttatt tatcagaagg tcttgctggc tttgccaaaa ttttacaacc
    11341 gattgccttt accagcttat tttcacgggt tcgttccttt cttgctgatt ttgccaattg
    11401 gttatttatg gcctagtact ctaggcggag gcaatcaaat cgttttagct tttggacatg
    11461 cttccttgcc aatcattatg attatcggtt tgtttgttct tcgattcgtt ttttccatga
    11521 tttcttacgg tggtggtctt ccagggggga ttttccttcc gatattgaca ttgggggctt
    11581 taatcggtag cttttatgga aacattatgg ttgatttcgg gatggatcca atctacatca
    11641 aggattttgt cgttattgcc atggctggtt atttcacagc gattggaaaa gcaccgctga
    11701 cagcaattat tttagtgaca gaaatggttg gctctcttaa tcatctgatg cctttaggat
    11761 tggctgctct tgttgcttat atcgtcaatg accttctcgg cggtaatcca atttacgaat
    11821 cattattgga acgtctactt ggaaatactc agaccgcctc actaaaaggt gcaaggacaa
    11881 cttttgattt tccagtaacg gcagagagtt ctttagacgg attaatggta cgagacttca
    11941 attggcctaa aaatatgctg ctaatctcta tacgcagagg aaatcaggaa atcttgactc
    12001 acggtgatac gatcatgaat gtaggagata ttttggttat cttgactgat gaagcaaact
    12061 tgccaagaat caagcaggaa atcgaggcta aatcttctat cacaaatttg aagcaatcat
    12121 tttaacgaac atggaaaaac tattttacaa caactattca tctacactac ttgattctat
    12181 atgattctat aaaaaaagaa gagactggga aaaaccagcc tcttcttttt tatttctatg
    12241 cttctgctgc tgcaggagct tttctcaata aaccataaat cacaccagat acgactgctc
    12301 cgatagcaat aaacaccaaa tacatgaccg ggtgactcag taagaataca acgaaaatcc
    12361 cgccatgagg agccagtaat ttgatcccga aagctccgac taatccgcca gttaaagcag
    12421 aaccaataat aaaacttgga atggcacgaa tcgggtcagc tgctgcaaat ggaatcgatc
    12481 cttccgtgac aaacgatagt cccatcacga tgttcgtcaa accagcatct tgatctgttt
    12541 tgctgaattt attcttaaac aaacgtgtag caacgaaaat tgccaatgga ggtaccattc
    12601 ctccagccat aacagaagcc atcacgacac ttccgccagt tgcaacagtc gtagctaaag
    12661 ttgctgtacc aaacacataa gcggctttgt tgattggacc gcctaaatct gccgccatca
    12721 ttccagctaa taatgcacca agtaaagcag cattcgaacc actcatactt gtcaagaaac
    12781 cgttcaatgc atcattgatt gctttcatag ggacattgac cagcaacatc aagaaaccag
    12841 taatcagtaa gccaaacact ggataaaaga ggatcgtttt aattccatcc aatgattttg
    12901 gtaagttctt gaataattta cgtaaaaata cgatgacata accagctaag aatccaccaa
    12961 tcagtgcacc taagaatcct gcaccgcctg tattagctaa tgcaccagca gcaaatccaa
    13021 cgatcaaacc agggcggtca ccgatacttg aagcaataaa tcctgctaat accggcagca
    13081 tgaaaccaaa tgcagcttgt ccgatttggt tgaaccagct agcagcttga ttgtaattcc
    13141 ctagatttga taattgatca tgtggcacgc caataaattg gtcgatcatg aaagaaagcg
    13201 caatagcgat tcctccacca ataacgaaag gtaacatgtg tgatacgccg ttcatcaaat
    13261 ctttgtaaat tctttgtccg atagtaccat ccgcatttcc ttcttctgaa ctgctttctt
    13321 ttccatcacc atggaatact ggtgcagtac cactaagggc tagattgatc agctcttctg
    13381 gtttacggat accatcactg acaggacgat tgatcagttc ttttccgtca aagcgattca
    13441 tctctacttt tttgtctgct gcaacgatta caccttctgc acgggcgatg tcttcagcag
    13501 tcaatcggtt tttgattcct tctgaaccgt tcgtttcgac tttgatctcc acacccattt
    13561 ctttcgcttt tttcttcaga gcatcttctg ccatgtaagt gtgagcgatc cctgttggac
    13621 aagctgtaac ggcaacaacg aattttcttt ctggatgagc agaagcttct gcagcttgtg
    13681 tttcttgttc tgctttttct tctgcttctt tttgctcttc agctgtttgg aacaagtctt
    13741 ggacttcttc tggtgtattt gcttctttta attttcctac gaaatctgca tcaatcagca
    13801 atcgagatag tgctgctaat gcttgcaaat gtgtgtcgtt tgcgccttct ggagctgcga
    13861 tcatgaaaaa cagataagtt ggctgtccgt ctaaggcttc ataatctact cctttttggc
    13921 tttttgcgaa taaaactgtt gcttctttaa ctgcactgtt tttcgcgtga ggcatggcga
    13981 ttccatcacc aagacctgta gaagtttgtg cttcgcgggc tagaattcct tctttatatg
    14041 tttcgatatc ggaaatccgg ccggcatcaa acattttttg gaccatttca tcgattgcgc
    14101 cttttttatc agtcgcttgc aaatccatga tcatcgcttc tttgaccatt aaatccttga
    14161 tattcatgat tatcctcctt gaaactaatc aatttttgtg atttcaactt ctggcagcaa
    14221 ctcatcaatc aattcgcgag ctgccaagtc atcagaaaaa gctgttgcgc ttccgcaagc
    14281 aactccccat ttaaaggctt cgattggatc tttcgtacgg ctgtaagccc caataaagcc
    14341 ggcaatcatt gaatcccctg cacctactga atttttcaat gggcgaacta atacattcgt
    14401 tttataagtt ccttgttccg tgaagagcaa agcaccgtct ccagccattg agatcagcac
    14461 attctgtgcc ccttcagcta gcaatttttt accatacgga atgatttctt ctacagattg
    14521 gaaggttgta ttgtaaagct cagctaattc gtgattgttt ggtttgatca acaatggttt
    14581 cttaacaagt gcatttttta ggtcatcacc tgttgtatca atcacgaaat ctgcaccttt
    14641 ttctcgaatg atatcaatca gttcttgata aaatcctttt cgcaggctag ccggcgcgct
    14701 tcctgacaat acgacgatat ctccttgtcc tactgttcct aatgcttgct tcaactcatc
    14761 gatttcttca tctgaaatag atgggcccaa accgttaatt tcagtttcag tatctgattt
    14821 tagtttgata ttgattcttg tatcttcttt tacggttgtg aacaaagact ggatttgttc
    14881 tttttcaagc cacttcgaaa taaattcgcc agtgaaccct cctaaaaacc ctagtgctgt
    14941 agattgagaa tcgatccgtt tcaaaatacg ggaaacattg atcccttttc ctccaggtaa
    15001 cttgaagtct tccttcattc ggttcaaatc gcctagtttt aacccatcta cgcgtacgat
    15061 ataatcaatt gatggattaa gtgttactgt gtaaatcatt gtattgcctc cttaattgtt
    15121 gtcttttcac ggaattcatt aacgaattct aatggacaac gctcggttat gatcgtggct
    15181 gcttccaaag gtgcaacaga ggtgaaggac aactggttga atttggtatg atcaatcaat
    15241 acaaatgtct cttcggaatt tttcatggct aaacgtttaa cagctgcctc ttctgggtcc
    15301 ggagtcgtga atccttgttc aagatgggca ccgttcattc ccataaatgc tttattaaaa
    15361 tgaaaatttt ttagttgttc tatcgcatta gatcctaaaa cagcattagt tgccagcttt
    15421 atcgttccac ctaaaataat ggtagcaagc tccaaatcaa ctaaatttgc cgcatgttga
    15481 acggaatttg tcactactgt gatctgtttt ccttgcagaa aaggaatcat ttctaacgta
    15541 gtagagccag cgtctaaata aatgacatct tcgtcattaa tggtttcagc tgccgatttg
    15601 gcgatttgct gtttttcgtg aacgtttttg agtgattttt cactcatatt ctgctcaaaa
    15661 ttcaataatt gctctttctt agctccgcca tgaactcttt ctagaaaccc actattctcc
    15721 agctcttgta aatcacgtct tatcgttgat tcagaagcat taaaaaggtt tacaagatct
    15781 tgtgatttca cgattttctg ctgttcaagc aagtctagga ttttttgtct acgttcctct
    15841 gtaagcattt tcacgatcac ctcaatacaa ataatagcat attttttttc tactcgcaat
    15901 ataaatcagt caaaaacgtt cataaaaatt ataaatcagt caaaaaaaaa taaaaaacca
    15961 gtcaaaaaga ctggtttttt atttttttgt ctatcatcaa gccgttttat cgttttttat
    16021 tttcgcttct tgtttttttc atataaacag aagcaggttt tctttcctta tgaagaagat
    16081 aataataaag tcccatcccg ccaaacatga ccaaaaaacc gatgactgat cgaataggaa
    16141 aattaggaac aaaaaagaga cagacggata ataatgatgc cggaaccatt attcgataat
    16201 agagttgttt atccattttc ttcacctcat attttttgta aagtaatcaa ttgttctaat
    16261 tctcggtaat ctaaaaattg cacacgcaga tgctgctcac ctttcttgac atcgaattgg
    16321 atacttcgcc gctttttctt tattcgtttg aaggtaacat cagagagtct atgtttgatt
    16381 tcctttaacg gtaattctga cagggattct gaaggaacat agattcttaa ggataaaaga
    16441 tactcttgat atttttcatc tgttacctct acttctagat attccctaat ataataacaa
    16501 taagcttcga ttccattatc caaagcaaca gtcggatcga taactttata gcacatcatg
    16561 cgcgagcgat tctcgtcaac ccaaggaaaa tacgcctgag catttagtgt tccgcgaaca
    16621 cgcctttctt tataatctcc ttgttgaata tcataacttt ttgttacaaa aaatgaagca
    16681 ttctttttag gaacaggttg catttgtgca ttctgatact ggacagattg gatcgtatgg
    16741 tcagtgtaaa tgtattcaac gaatggcggt ttcaataaac cgacaccatt gtcccaagca
    16801 agatgatcaa acccaagctg gtccctaaaa taggattgaa acatttgatt gtttggcttt
    16861 tgccagttaa aggggtctcg ataaagctgg atacatatga cttcgttttc taattccttc
    16921 actttttcta cttgttggat gtcgagaaaa atcggtttag ggatgatttg atgataatag
    16981 cgactataat acatttccca acacgaagtg aaacataaac cttggtaaaa aagatcgtat
    17041 cctggaaatt ggttgcaatc gactactact tccccgtttt gttgtttcat tttaggtaaa
    17101 tgttcgattt catccttttt ctcaaacaat agccgttgag agatctgttt tgtattgtga
    17161 tagataaact cgctataagc tcgcatatag gcgaacaccc catgagcaat catttttttc
    17221 tgaatgaagt ctcgaatcaa aaattgcttt tctttgaaaa cagagataga caatacattt
    17281 tttatcaata attgattatc ttccaagcga aaactacatt cgttctcgtc atttcctaca
    17341 actaaccaac tttcgtctct taccgatgct agcattattt tttcttgaag ctttcgaaga
    17401 tcatacggat ccgcttgttg tgtgaaagag cggataaatg ttggctggat caacagacgt
    17461 gtcaaaatag cccaatcgct tatttcctgt tttttttctt cttcatttaa gtctgtgagc
    17521 tggatagtca tcaataattt atcttcgcca atcattttct cacctcttta aaatcttttt
    17581 ataatttaat tataaccaac gataaagaaa aactaaaact ttatgtctta gaaaccaatt
    17641 tggacgatta catgatagac taagtaaaaa gaaacaaaga ggtgtttaca atggggttga
    17701 aatttgaacg tacagataat ttagataaac ttttcgaatc atttgctgtc gatccggaaa
    17761 aaacagttgc accaaaagaa gagatcgatc gatttctaaa accacagcca caaaatgaaa
    17821 agaaaaaaga caagaaacaa aagtaagtta agctcaaaaa aagacttacc agccaaactt
    17881 ttatgaaaga gtttgactgg taagtctttt ttattctttt tatgattcaa ttgcttgttc
    17941 gattgctgcc cacgcttctt cttttccctg ttttgtaacg gaagaaaaga gaataaacgt
    18001 gtcattgcga tcaaaatcca acgctttttt gatttcgctc tcatgcttgt tccatttacc
    18061 acgagggatc ttatctgcct tagtggcaac aacaattaca gggatatcat aatacttcaa
    18121 aaattgatac atctggatat cttcttgaga aggcttatga cgcaaatcta ctaaagaaac
    18181 gaccgcacgt agctggtctc tagtcgttaa atatgtctcg atcatctttc cccattttgc
    18241 tcgctcagtt ttggatactt ttgcataccc atatcccgga acatcgacaa aatgtaatgc
    18301 gttctcgatc aaataaaaat tcaatgtctg ggtctttcct ggcttaccgg aagtacgggc
    18361 taaattcttt cgatcaatca atgtgttgat aaaagaagat ttccctacat ttgatcgtcc
    18421 tgccagagct atttctggca attgtgtatc tggatattgt tttggtgcca ctgcacttat
    18481 gataatttca gcttgatgga ctttcatggt ctctctcctt aacaaggtga tgaataaagc
    18541 aagcggctgt cgcaaaagcc aaaatgactt ttacggcagc ctcttttcat caacccgctt
    18601 ttttctctga atctttatag attactgttg gctcaccaga caattcagct gcttcttttg
    18661 tgataatcac tttttcgatg ttttcatttg aagggatatc aaacatcaca tccatcatga
    18721 tttcttcaat gatggaacga agtcctcgag caccggtatt gcgttcgatt gcttttttcg
    18781 caatggctct caacgcttca ggttcgaatt caagttcggt attatctaga gaaagaagtt
    18841 tttgatattg tttgactagc gcatttttcg gctcagtcaa gatccgtacc agatcatctg
    18901 ttgtcaattt ctctaaagct gccataacag gtaatcgtcc gataaactca gggatcaatc
    18961 cgaattttag taaatcttca ggaatgatat gctgcatgac actttcgtct tcagaaagtt
    19021 tttggttttg tgtaccaaat ccaatcgtct tttcgcccat acgattcttc acaatcgttt
    19081 cgatgccatc aaatgcacca cctacgatga acaatatgtt cgtcgtatca atctgaataa
    19141 attcttgatg tggatgttta cgtcctccct gaggtggcac gcttgcaaca gttccttcta
    19201 gaattttcag caaggcttgt tggacacctt cgccggaaac gtcacgagta atagatacat
    19261 tttcgctttt acgcgcaatt ttatcgatct catcaatata gatgatccct ttttctgcac
    19321 gttccacatt gtaatcagca gattgaagca atttaagcaa aatgttttct acatcttccc
    19381 ccacataacc agcttctgtc aaacttgtcg catctgcgat tgcaaaaggt acattcaatg
    19441 tttttgctaa tgtttgtgct aaaaatgttt taccagaccc tgtaggtccg atcaagcaga
    19501 tattgctttt ttgcagttca acatcatctg tgttttcttg tgcttgctga ttgacacgtt
    19561 tatagtgatt gtatacggca acagctaacg agcgttttgc gcgatcttgt ccaatcacgt
    19621 agttattcaa tacttcaaga atttctagtg gtttagggac ttcagtgaat tcgcgtacag
    19681 cttcttcata aaattcttca tcaatgattt ctttacatag gtcgatacat tcattacaga
    19741 tgtagacccc tggaccagct acgatctttt tcacttcttc ttgggttttc ccgcaaaaag
    19801 aacagcgtac ggtctcattg ctacttggat tgtcatacat ggtcttcacc ccttaacttg
    19861 caaaaagtat gcaagaaact atcaaagact ttacagtctt ttactatcat aacatagttt
    19921 agtaaaaaga aaaagtgttt aacaaaggat caactgacct atacctttgc attttttact
    19981 cttaacaaaa aataaggaac tgtgacaaaa tcgtgtcaca gtcccttatt tcgaataaac
    20041 aattttctag aagtagcttc ttcagaaatg atttattact tgatttctat tctttcgctt
    20101 ctgtcgctgt acctgtgatc aattcgattg cttttttcat tgtcacatca tgttccagca
    20161 tatcttctgt caacacgcgt ttgatttgtt cgattggcat gttgtatgtt tctgataatt
    20221 cttggatttc tgcattgatt tcttcttctg ttgcttgaag attttcagca gctgcaattg
    20281 cttcgatcac aagatttgtt cttgtgcgca tttctgcttc accttcgaat tgtttatgca
    20341 agtcttcttc tgtagaacca gttaattgat agtacatttc aggagagata ccttgacgtt
    20401 gcatgttgtt caagaattcg tccattgaac gatgtacttc atcatgaacc atcacgtgtg
    20461 gcaattcaac gatttctgcg ttttcaacag ccatacggat cgctgcttca tcttttgcat
    20521 cgtccgctgc tttttctttt gtttctacta attctttgcg atatttttct ttcaattcgt
    20581 ctaatgttga tacttcgtca tcaacatctt ttgcgaattc gtcatctaat tcaggcactt
    20641 cttttgcttt tacttcatgg attgtcactt tgaagactgc ttcttttcca gcaagatctt
    20701 ctgcttgata atcttctggg aaagttacat ttacatctag actttcacct gatttatgac
    20761 caactaattg atcttcaaaa cctggaatga atgagcctga acctaattca agtgagtaat
    20821 tttcgccttt tccgccatca aacgcttcgc catctacaaa gccttcgaag tcgattacta
    20881 ctgtatcgcc attttcagct gcagcatctt ctttgataac taattcagct tgtgcttctt
    20941 gttcacgttt gatacgtgca tccacgtcag catctgttac ttcacggtct tgtttttcaa
    21001 caactagatc tttatattgt cctaatttta cttctggttt cactgttact tcagcagtga
    21061 ttacccagtc ttgacctttt tccatgcttt caacatcgat ttttggttga gaaacaggat
    21121 cgatgccagc ttctttgaca gcagcttcat aagcttctgg taatacagca ttcaatgcat
    21181 cttcatataa agcttcttca ccgtacatac ggttgaatac ttgacgagaa actttccctt
    21241 tacggaatcc aggtacgttc aagctttttt tcactttatt aaacgcagtt gttaatcctt
    21301 tttggatttc gtcttgcgca atcgtaaatt ttaaaacacc atcattcgtg cctttttttt
    21361 caaatgttgc agtcatttaa ttccctccga gtttagaaat tcattttata catcaaaaac
    21421 gtttcatgca tacctttaaa tagtacacta accctttcaa attgtaaaca tattgaatgg
    21481 atagaatcct tgtttttcat aacattttta tctttttcac tgataaaatc taatggaaga
    21541 agatcatttg ctgcaaaatt ttttctcttt tttttaaaaa atcttgtttt tcatcttctg
    21601 taccttcata catcgttttt cctgtacacg cctctacagt cagttgaaac cagcgcttcg
    21661 ggtcttcgat gtatgtatca tagacaggat aaacaattgc agattgcaac gtgaattctt
    21721 catttaacac ggaactaagc agcgcatctt cattaccgta acgatctgaa aatacacata
    21781 attgctggta acttgcctgc tgctgcggct ttggcagatc ttttggtatg actttgacta
    21841 acttttcttc aatcgtcaaa tagaaaacag gatggcattc gttcaattgc ctaagtgtct
    21901 ccagtaattt tgcccttgct aaaatatgga cctctggcga tacaataagt ttactcgctg
    21961 tttggataaa ctcatgataa ggaagctgtt cgatctcatc aatagacgca agctgacgtg
    22021 caggttccaa cgaaggaagt tcctccgatt tattgtggag tgccttgatc ttctgcctct
    22081 ccatttgtcc ggataattct tctgcaaatt ggattttttc aatgacccgc tgctcgaaag
    22141 cttcataaaa atctgtactt gctatcaatt ttctagcata taaaaaatct tgtgtactga
    22201 ttaacaagtc aaaataaaat tcagcaaact cctcattttg aagatactgt ttttcatgca
    22261 agagtgcttg cttcaatgct tcttttttct cgtccaactc gtaaagacaa aaaacaagca
    22321 ggctattagc ctcaaagctt tctttcaact cgtaagctcg ttgaaataat tcttttgcct
    22381 gctgatattg ctggtttgct agtgcttgtt gtgctactcg cattaaattc tcatattttt
    22441 ctggaaaatc aatcggcttc acgcagtgtc ctcctcttgc tcatgttcag ctcatgttca
    22501 atagtagcaa aacaaaaaaa gcatgacaat taaaaataac tgaagcaccc tctaaaagct
    22561 agattttaga tctgactttt agaaggtgct ttcaactgtt actgcttttt attgctcatc
    22621 agctgttgac ttcctggttg aatgctttga tcagattgat cgtaacaaca cttgtattag
    22681 tgaaaaaatc gcctagatgt tgctttttct gattaaagat tgctggaaga taccctaaca
    22741 tcagcaaagg aaattttaga atgaaccggc aagcaccttc tctaactaaa acggttgacc
    22801 agctaagttc ttcttcatca aagctgatga ctcgaatacc aaagatcatt ttcccaatcg
    22861 tttgaccatg attgaatttc gtcaataaaa taaaatacgc tagataaata agtaaggctg
    22921 tgaatccgta gatactcaga taagaatctg aaaaattaag ccaacctaga tttttggcaa
    22981 taccaagtgt taaacgcgta atagctccga tacacaaaag atcgaccaag aaagcaaaca
    23041 ttcggataaa aaaacctgca tagaaatact taggaaaatc atttgctttt ggcggttcat
    23101 ttcttgtgtc cgtatacttt ttccatttac gttgtttctt tttgatttct tcgggcgtca
    23161 aaggctctct ttcaaaagag ctcagtacct tttgggaaaa gttggagtca ggtcctacag
    23221 caggctgctg ttgcttatct ttttcttgtt ccttattttc atttgaaagc tctgacatgc
    23281 ttactcacct ccgtaataat acattgcttt tggtgattcc gctgtcccta gattctcaag
    23341 aacggataag atctgactag tctcagaagg cttcaatccc tggaattctg ctagtttact
    23401 tcctaaccat gtactagcaa acccagatgg cgtggaagaa tattctacta gttccgcatc
    23461 ttcaagctgt tgttcctttc gcatagcttt taaagcatct tcaggaaatc ccaattcatc
    23521 gactaaacct acttcttttg cttggacacc atcataaatc cttccatcag caattttttt
    23581 gacttcttct tcagatttat tccgtccctc gctgacgatt gctacaaaac gactatatgc
    23641 gctgtcgata tatgcttgaa gcaccgcttc ttcttctttt gtctctggtc gcgttcctga
    23701 acccatatct ttcaacgctc cgcttttaac tgttgtatct tccacaccca gtttttctag
    23761 aagtcctgaa taattcaatc ctgacatgat cacaccaatt gagccggtca ctgtttcttc
    23821 tgttgcaaag attttatctg cttgagcaga aatatagtag ccaccgctag ctgccatgtt
    23881 tttcatgctg acatacattg ggatatcatg ttctttacga atcgtatcca atttcttagc
    23941 gatttccgca ctttcgtaga caccgccacc aggagaattt acttctaaaa agataccttt
    24001 gactgttgga tcttcttcaa tcgccttcag ttgttccata aaatttttat gattgtaacc
    24061 ttcagaagca aataaacctg aagcccctcc cgcagcaatc gttccatcta ctgataattt
    24121 tacgattttt tgcgtactgt ctccctcttc caacacattt gaagctagtt cttcatcccc
    24181 atataaccaa ctgttcaatc cctcaatttg atcgttttcc tgaggcttag tcaaactagc
    24241 tgaaactaac gaaaccacaa ataatcctgc agcaatcaga actgctgccc aacgtctctt
    24301 attcattctt tctcctttct aatacaagtt ttttatgacg atcacagttt ctgactgctc
    24361 agaagtgtcg aaccgctctg ctttttcttc ccgcgcatac ccggaaaacg actcttttgt
    24421 caattcatct tctaccgtaa actcacgagc ttcagcaact tccaaggcat caggtgcgat
    24481 ttcttggatg ctatcccagc cagtatctaa aaatattttc gtatcatctg atacaccagc
    24541 tgatgcttcg aatttggaca attgtttttt taacattccc agtgtcatga tctcaatttt
    24601 tgaatccatt tttactcctc ctctatccga ttactttcta ttgtaccgaa ctcctgaaaa
    24661 agatgataga taaaaaccca ttattttttg acataaaaag agcatttgac aaagcatttg
    24721 atatatacca atttattttt tattcttttt ttgttgacaa gaacattcgc aaaaggttat
    24781 gattttaaat gtttccagat aaaaaacaaa agaggaggat agttatacct tttaggatag
    24841 cgccaggtct gtgtaaacag atgacgagga gagggtttat cgaaagattc ggcggatggc
    24901 cctagggact gcactctaca gaaaatccac aaaaaatatc tgcaaagata aaacaaaagg
    24961 attttcctgc agctggaagc attcatacga attcattata gaaagtagga tgttttttat
    25021 gtgcggaatt gttggaatga ttggattaaa aaatgtaaca ccaggattga ttgacggtct
    25081 agaaaaatta gaataccgtg gttatgattc agctggtatc tttgtctcag atggcacaac
    25141 tgattatctg gtcaaagcac aaggcagaat tcaaaatttg aaaaacaaaa taaatattga
    25201 tactacagga aatataggta ttggtcatac acgctgggca actcacgggc aaccttctga
    25261 agaaaacgcc catccacata cttcccaaag tggacgcttc gtgctcgttc acaatggcgt
    25321 aatcgaaaac tttgaagaac ttaaaattgc ttatttagca aatgaccact ttattggtga
    25381 gaccgatact gagattatcg ctcatctaat tgaaactttc gcgaaggata ctacaacgca
    25441 agaggcgttt ttaaaagctt tgcgggtcat caaaggttct tacgctttcg ctttgattga
    25501 tcggacagca cctgatgtta tttacgtcgc taaaaataaa agtccactat taatcggact
    25561 cggcgatgga ttcaatgtga ttgccagcga tgcaatggct atgcttgctc atacgaagga
    25621 attcgttgag attgaagatg aagagatggt taccgtcaca tcagaaaaag ttattattca
    25681 aaattttgca ggtgacatcg tagaacgttc ttcattcgaa gcacaagtag attcttcaga
    25741 tatcgagaaa ggtacctatc ctttttatat gctgaaagaa atcgacgaac agcctattat
    25801 catgcgtcgt atcgctcaaa aatacgtaac agaagacaat cgtgtctctc ttgatcaaaa
    25861 gctggtcgat acattgtctg atagcgatcg aatctatatc gttgcttgcg gaactagtta
    25921 ccatgcgggg ttagcaggta aacagactct ggaaaaattg acacagatcc ctgttgaggt
    25981 tcatttagcc agtgaatttg gctataacac acctcttctt tcaaaaaaac cattctttat
    26041 tttcttgagt caaagtggcg aaacagcaga tagccgccaa gttctggtaa aaatcaaccg
    26101 tctcggctac ccttcactta cgattacaaa tgttgctggt tctactcttt cgcgggaagc
    26161 atcctttaca ctgctattgc atgctggacc cgaaatcgca gtagcatcaa cgaaagctta
    26221 tactgcacaa atagctgtac taactttatt agccaaagct atcggtgata aaaaagaatt
    26281 tgaaacttct cttgtattcg atatcactca tgaattgagt ttagttgcta atgcgatgga
    26341 atcggtcatc gcccaaaaag attatttaga agagttggca gaagtatatc tcagcgatac
    26401 aagaaatgcc ttttacattg gacgtggcgc tgactacaac gtttctcttg aagctgcttt
    26461 gaaattgaaa gaaatcagtt atatccaggc agaaggtttt gccgctggcg aattgaaaca
    26521 tggaacgatt gctttgatcg aagaaggaac accagtgatt ggaatcatca gtgaagaagt
    26581 gactggtgcg catactcgag gaaacctgaa agaagtcgaa agccgtggcg ctaaaacact
    26641 agttattgtc tcagagggat tagaaaagga aagtgaccag ctggtgctac caactgtcca
    26701 cccttatcta actactctaa ccacagtcgt accgactcaa ttacttgcat attacgcaac
    26761 gctattacgg ggattcgacg ttgacaaacc acgtaattta gcgaaatcag tgacagtaga
    26821 ataataaaag aacaaggacc agtgtcagac atctgacact ggtccttgtt cttttatttt
    26881 ttatgaaaat atctcttaat ccagtccgat ttcttctttg actactgccg cgattttatc
    26941 gacatagtaa ttaactttct catcagtagg cgcttctgcc atcactcgaa gtaatggttc
    27001 tgtaccggaa ggacgaacta ggattcttcc ttctgatccc atttcagctt ctgcctcttc
    27061 aatcactttt ttgattgccg gaacatccat cgcaccgttt ttatcactta ctcggatatt
    27121 cactaatttt tgcggataga ttgttacctc tgctgcaagc tctgataatt tcttacctgt
    27181 ctgtttcatg atattcagta actgaattcc tgaaagcatc ccatctccag ttgtgttaaa
    27241 atctaagaaa atcatgtgcc cagactgctc gccgccaaag ttataatcgt ttttgcgcat
    27301 ttcttctaca acgtaacgat caccaacttg tgtaacgaca tctttcaaac cgattccttc
    27361 caccgctttg tggaatccta agttactcat gacagtcgta acgatcgtat cttttttcaa
    27421 tcgatttttt tctgccaagt atttagcaca gataaacatg attttatcac cgtcgacaat
    27481 gtttccaagt tcatccaccg caataatacg atcgccatcg ccatcgaaag ctagtccagc
    27541 atctgctcct ttttcaacga ccatctcagc taaacgttct ggatgggtag agcctacgcc
    27601 atcattgata tttaacccgt ctggatttgt gcccatggta taaaaatctg tttcaagatc
    27661 ggcaaacaaa cgattaacac ttgttgaagt tgctccgttt gctgcatcga cacaaatggt
    27721 caaaccggaa aggtcaccgt tgatcgtttg tacaaggaat tgagaatatt tcaataagcc
    27781 ttctggaaat tcttctacag ttcccaatcc ttcagctgat ggacgaggca attcatccac
    27841 ttcagcatct aataatgctt caatttctag ctcttggtca tctactagtt taaaaccatc
    27901 tgcaccgaaa aatttgattc cattatcttg tgctggatta tgagaagcag aaatcatgac
    27961 ccctgcgctt gctttttgca aacgtgtcag ataagcaaca cctggtgtag agatcacacc
    28021 tagctggaac acttcgatac ccaccgataa aagtcctgaa atcagcgctt cttctaacat
    28081 ttgacctgag attcttgtat cccgccctac taacacgcgt gggcgttttc cttcttcttc
    28141 atgctggctt aggacataac ctccgcaccg tcccagctta aatgcaagtt ctggcgtaag
    28201 ttccttgttg gcttcaccgc gtacgccgtc tgttccaaaa tatttaccca tagttgtaaa
    28261 attactcctt taacttaatt ttctgaggaa tttgttctgc tcatttgtgt tgattcgctt
    28321 gtttctgatg tttcttctgt acttgtggtc gagctgcttg tcccagattc cgaactggaa
    28381 gaaatggttg ttgtcgatgg ttccgttcct gaatcagcag atgaaatact tctactcgta
    28441 cttgtatttt cttgtgtccg actgctcgtc gaagcagagc tactgcttga cgtttgcaac
    28501 acgggtgtaa tctccacact aactgattcg ggcttgatac ttaacccctc ttctactggt
    28561 atttcaattt tacgagttgt tcgatgattg atacctgaga cattgatcgg tacagcaata
    28621 ctgtcaccga tcgatgcaag caaatcgcta gagccgctta cttctgcttc cagttttgaa
    28681 aaactgaaat catagctttc taccccggca gctggtgttc cttgctgtat cccataaagt
    28741 cgtaccgact tgcttggctt gatcgaatca gctctcactg ttacttgcac tggatcagag
    28801 acgatactta atacttcccc tgctgcattc agcgcctgta ttgggacctc actattaatc
    28861 ccatcatctg tgaccatcga agcgtccaca tcagctacta ctcgtttgat ttctgccaat
    28921 gttttgtcac ctgtagtgat agagactttt ttaggactaa cggaagtatc atcaagttca
    28981 tatccagatg gtgtgaacgt tgaaggaatc aacgtttcca catcgaaatc ttttattacc
    29041 tttttctcaa ccgttactgt aatagtcgat ggttcgatct ttgctgtgac agcactgctc
    29101 aaattttgaa tttttagcgg aacctcatgt gttccttcgc ccagcttagt gatatctgct
    29161 gtgacgcgga acatccgtgt atcttcgttt gcctctgcat tcaactgaac tcggtttgca
    29221 ctggaaagtt tgacagtcac tgcattttca tatccatgga tatagtagcg ctttgaatca
    29281 taagaaatct tgattggcac cccagtaact gtttgattat acgcttcatt tccagaaagc
    29341 gtatttggaa cggactggcc atttgcattg aagtacagcg caatactgaa cagcaatgca
    29401 ataaaactgt aaagaatgct tgtccgtttc tcttttgaga tcatttgcga tcccctccct
    29461 tagtcatacc gtctaggaaa gattgaatca cgtttttctt gttttttgtt ttctcttcag
    29521 caatcagttc tctacgcaaa attgccaaat attcttgctg ggataagcca gccatcagtt
    29581 cattatctaa tgtaatgctg acatccccag tttcttcaga gacaacgatg gtaatcgcgt
    29641 cgctgacttc gcttataccg acagctgccc ggtgtcgagt cccgaattct tttggaatca
    29701 acatactttc tgatagagga agataggcgc ttgctactgc gatctttcct tcttttacaa
    29761 taactgcacc gtcatgcagc ggtgtattag gaataaagat attgatcagc agctctccag
    29821 tgatatctgc atctaatgca attcctgtct caatatactc atctaatcca gtatgccgtt
    29881 cgatagtaat tagcgcaccg atttttcgct tggacatata ttggatggct ttgtcaaaag
    29941 acaagatcat cttctcatct tcctgctgtt cgctttttga ttgtttgaaa agcgaactgc
    30001 gtccaagatg ttccagtcct ctccggattt ccggctgaaa aatcacgata gcagctatca
    30061 ccccgtacgt aatgacttgg ttcatcagcc aagacaaggt gtgcagacca atgatttccg
    30121 ctacgattcg gataacaata aaaatagcta cacctttcag aagctgaatc gcttttgtgc
    30181 ctcgcagcag ttggatcagt ttgtatacaa gataccagac aaccagaata tcaagtatgt
    30241 tcaccaaaaa attcagagag aacaagtcac cggaaaacat ttgctgccaa tagtccaaat
    30301 taaaaagttc cccgatttga aatgacataa aaagcctctc ttctcttttg agatttcctc
    30361 tctagtatat catatgtttt aattttagag gctgatctgc tcgtattttt cttgagaaaa
    30421 acgcataatt ttcaggaaaa ttgcaagtat gcgttttatt tttctctgca ataaatattt
    30481 ttaaacttca gagaattatt cattatattt tttctgttat ttttcctttt tttcttttgt
    30541 agcttgttcc atttttttac gtcgttctgc tctggcagct cttctttctt ctgcttcaag
    30601 gtccgtcgtt ttttcttttc tagtcttaac gggtacatcg atagattcct ctggttcaag
    30661 tcgtttcttg attttttcta attctcccgt cagtgcagca tagttgtaaa aacgtgtttt
    30721 agcgtcttgg atagtctttt caaataaagc ttttgcaaga tttggatttg cgttctctag
    30781 cgaggaaaag cgaacttgtt tcctcatgaa atcaggcata gcagagaaat caggtttttt
    30841 gtagtccaaa gtcattgggt tcttgttttt ttcgaccatt gcagggttat atcgatataa
    30901 tgaccaatag ccagaagaaa cagcttcttt tgcttcttta agcgattctt tcattccacc
    30961 aagcaaacca tgtgtgatac aaggcgtata ggcaatgatt aaagaaggtc caggatactt
    31021 ttctgcttct tcaaaagcct ttatcgtctg catttgattg gcacctgaag caatttgcgc
    31081 cacataaaca tttccatatg tcatcgccat cattcctaga tctttctttg aagcatactt
    31141 tccactagcc gaaaatttag cgattgccga agctggtgtt gcttttgagg tttgaccgcc
    31201 agtattggaa tagacttcgt tatccaaaac aagaatattc acgtctgctc cgctggcaag
    31261 tacatgatcg atcccgccaa aaccaatgtc gtaagcccat ccgtctccac caatcatcca
    31321 ttggctgttt tttacgaata gatcctttct cttgtatata tcctccagtt cagggacaat
    31381 tgatcgttcg ctttcgatcg cagcttgcag ttttgctgct ctttgctgcg ttccttcgct
    31441 ctcaaacatg tgtaccaacc agtcttccat caattctcgt agttcttctg atacttttgg
    31501 caatacttct ttgattgaac ttgccaaagc ctcgcgacga gtctgtgccg ctagaagcat
    31561 accataacca aattcagcat tatcttccaa taaagaattt gaccatgcag gcccttgacc
    31621 acattcattg gtcgtataag gagaagcagg agaagcaccg ccccaaatag aagaacagcc
    31681 tgtcgcattc gcgatcatca ttcgatcacc gaacatttgt gtcaataatt ttacataagg
    31741 tgtttcgcca cagcctgagc aagcgcccga gaattcaaga agcggttgat tgaattgtgt
    31801 agacaagaca gtattctttc ctttgactgg atttgctttt tgtcttaatg tcattgcaaa
    31861 agcccaattc acagcttgtt ctttctgttc ttcataaggc ttcatcacta aagctttttc
    31921 ttttgcggga caagcctcta cacacagacc acaacctgta cagtcttcca ctgaaacttg
    31981 gatacggtat tttacgccgt ctgcgcctcg catttctctc acgataaatc cttctggcgc
    32041 ttcttccatt tcctcttcat ctgctaaaaa tggacggatg gcagcatgag gacaaacaaa
    32101 ggcacattca ttacacatcg tacagcgatc actaatccac tcaggtactt ctaaagcgac
    32161 gccccgcttt tccatagaag ccgttcctaa aggcatttcg ccagttgtca ttccatttgc
    32221 tacaagtgta ccaacagaga gttgatttcc ttcctgtgca ttcactggtt caagtatttc
    32281 ttgtatataa ccagtgttcc ttttattgat tttttcaggc atctccaacg ttctccaatg
    32341 gtctgggatc gcgacttgat gaagcagttc ggtcgtccga tcgattgctt gtatgttttt
    32401 ttctacgata gccattgatt tatgtccata gcttttcagg gcttcttctt ttagcagcgg
    32461 aagcacctca tcaaaaggaa tgatgtcagc taatttaaaa aaagccgttt ccattgccgt
    32521 attgatccgg cgtcccaaac cgacttcttg ggccaatctc atggcattga tcgtatagaa
    32581 tctaatgtta ttttcagcca agtaacgttt taattttaag ggcagatgcg tttctaattg
    32641 ttcgtcgctc caaagagtat tcaataaaaa aatgccacct ggcttcaatc ctttgaccaa
    32701 gtcatagcta tgcaggtaag ctggtgtgtg acaggcaaca aggtccgcat gctcgacaag
    32761 atacgctgaa cgtatcggcg tatctccaaa acgaagatga gagacagtca gaccgccaga
    32821 ttttttcgaa tcataataaa aatagccttg cgcatattta tcggtgtgat ctccaataat
    32881 cttgatagct gatttatttg ctccaactgt tccgtcagat ccaaatcccc aaaacttggc
    32941 ctggaatgtt tgcggttctg tcaaatccag actttccttt ggttccaaag attgataagt
    33001 cacatcatcc acgatcccta tggtaaaccg ttttttgcgt atgcttgggt cttttttcaa
    33061 ttcatcaaaa actgctgaga tttggtcggg agtcacatct ttagacccca atccgtagcg
    33121 accaccaata acagccgggc gaagttcaga atcatataac gcactttgaa cgtctaataa
    33181 gagaggttct ccacctgccc ctggttcttt acttcgatca agaacagcaa ttgtttttac
    33241 tgtatgaggc aacttttgca cgaatgtttc cactggaaaa ggacgataaa gatggatatt
    33301 caaaaaacct gttttccgtc cgtttgcatt caagtaatca atcgtttgtt caatcgtctg
    33361 tgcaactgat cccatagaaa caatgacttc ttccgcatcg tctgctccgt aataagtcac
    33421 caagtcataa gaagttcctc gtaatcggtt gatctctttc atatattttt gaacgatttc
    33481 aggtaattta tcataatagg ggttgatcgt ttcccgttgt tgaaaatgga tgtctggatt
    33541 ctggttcgta ccactaacag tcggatgatt gggattcatc cctcgtttac gaaatgaagc
    33601 taatttctcc tgattgatca gaggagctaa ttcttcatat tccaaaactt cgattttttg
    33661 aatctcgtga ctcgtacgga atccatcaaa gaaattcaaa aaaggtactt ctccttcaat
    33721 agaagcaaga tgggcaacag gtgctaaatc catcacttct tgtacactgc tttcagctaa
    33781 catagcaaat cctgtttgtc ttgcagccat cacgtctccg tgatctccga aaatattcaa
    33841 cgcatttgtc gtcactgccc gactagcaac atggaaaaca cttggcagta gttccccagc
    33901 aatcttgtac atattcggta tcatcaaaag cagcccttga gaagcggtat atgtagttgt
    33961 cagtgcacca gttttcaatg atccatggac cacaccagct gctcctgctt cggattgcat
    34021 ttctactact tttactggtt gaccgaatac attttctttt cctgctgctg accattgatc
    34081 tactaattca gccatggtcg aactgggtgt tattggatat attgcagcaa tctcggtaaa
    34141 tgcataagaa atatatgcgg ctgccgtatt gccatccatt gttttcattt ttcgcatgat
    34201 tcatcatcct tgttcatatt ctctcttatt atctgttcca ttataacgta aaacattcca
    34261 ttttttcttt tatttataaa aatatttcac atatgtctat ttgaattggt catctaattt
    34321 ttagacaaac agtctaaatc gttgcctttt tttgtcagac atgtataaac tataagcgaa
    34381 agaggtgttt taacatggat atatcagtga ttgatgcaac gaaaacaaat acacaaaaag
    34441 gaatccttta tggttcatcg aatgctccta aaaaaatggt cgaattcatc aacctatctt
    34501 gtccgtattg ccgacaatgg tttgaagaat cttatgagct attagaagaa gcagtccaaa
    34561 gcgggcaatt gcagcgagtg atcaaattgt tcgataaaga aaaagaaagc ttgcagcgag
    34621 gaaacgtgat gcaccggtat ctcacaatca gcgatggtca aaaagcgatc aaagagatca
    34681 aacaaatatt cgatactcaa gacgagtgga aacatctttc tctccaagaa gtagcggatt
    34741 ttgcagtaga taaactaaag ctgacagaac aaaaagacga acagctgagc caagctgtca
    34801 tcaacgaagc tgagcaagca catattcgat ttgttccgac tgtcatcttg ggtaaagaaa
    34861 tctttgatga atctatttca atagaggaat taaaagaatt gatccaaaca aaataaaaaa
    34921 ataaggagcg taggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacctataaa
    34981 cggcggaagc agaagcaact ccttcttatt tcttggagtt aaacgcttct gtcccagcct
    35041 ccttattccg aataaatggt gtccaaaagc ttgcatctgc cagattatct catttcttat
    35101 gacaagctga gcaaattatc tccaccaaat aatttattca tatttttgac ttgcgcatac
    35161 taactaattc ttaaattttc atacaaaatt tctcaaattc ccttaacgag taatatttat
    35221 gtacggtgat tcacactagt atcccaatca ctttttaagt tatcccgatt tcaattctac
    35281 ttcaaaaata gttgctttta tgtatgctgt tagttgatta gatggtcgtt tgttgagcta
    35341 ggtcgtttat tttaaacaag ttgtttcttt agcttatacc tatctcgtct accaaacgca
    35401 agatggcaaa cacaaatgca tacgcatctg tatttgccac tttgattcgt ataaagctaa
    35461 caactcctaa ctcctctcat ttaatagttg ctctcttttt tattcagata catttttgct
    35521 gatcacagcc tagtatttca atggttttga acactaaacc aaattgttcc attacaacat
    35581 tcactggctg atgaaatgga ttaatagatt tcgattattc aaagcgattt tctattggtg
    35641 gattgtgttc ccaactaaca agacggattc caaagtcatt atataactct tcaagagtta
    35701 accctttcct gttcccaata gatgtatctc tcccacgctc gatataaaat atggagtttc
    35761 gaatgccaag acctggcaaa tctttccttg ttacagttac actgctacta acttccccat
    35821 ataaaatcca gctcctccaa aatgataata tatttttcga ccatcatcta actcatgtaa
    35881 caataattgt tgtgccctct tgtcactcgc caaatgcaaa cgccacgtgc gataccatgc
    35941 catgctacct gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac
    36001 aatcctttcc ccatctactt catattctaa tctaaaatca aactcccctc gggtaatcgc
    36061 aggtcttggt ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg
    36121 aaacacagct ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat
    36181 tattcgcaaa tcacctctac attctcacat actagttcgt aatactcctt taatatcaaa
    36241 atatctactg atcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca
    36301 aatcatcagc ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct
    36361 aatcaccaaa attgttaaca atcggttcag atatttccca attcactagc cttatattat
    36421 attgatttaa caattcttct tcatttattg tattttgatc aagcggacca aattgttcta
    36481 ataattcttt gtcatgtaaa atatcccttc tagtaatgcc tctttccctt tcaatgaaag
    36541 aagcactagg aaaagtatga ttataaccat tcaacctatc tcccatgtaa taattagcag
    36601 gtcctggaaa ataaaatatt tgcttattat cactaacttc taacagcaac actaaatctt
    36661 ctccgctggc taaacgactt gtccatctac gatatctccc tatgccttcg ttcattccaa
    36721 atccatcaaa ttcaactatt aacgtgtctt ctatcacatg taattcttca ttcaattcat
    36781 actcaagtct aaaaggaaat tctccatatg taatctctgg caatggtggt gctggagttc
    36841 tccaaataaa tacaataact gtgaatagaa aaaatccaac gatcgatata aatgttatga
    36901 gacctgctcg aagtaaaacc cgatataata aaaatgctgt atttcgcttt gctatatcta
    36961 gaaaaataaa aagtactgca atcataatga tagtaaaagt tgtaaaaaaa cgcatttttg
    37021 ccctcccttt ataaacatcg attctcaaat tctaaaccaa atcttggtag ttcaagttca
    37081 ggtataacgt attccaacca tacatctcaa ttactattta tgaacttatg attatcactg
    37141 aataaatcac tccatcccct tgttaaaact tctacattaa ttacacctgg ttgttttcga
    37201 ctagctaatc caatgaactt atcaaccatc cttatccacc aaccacgaga atcttgacca
    37261 gaagtaagaa gagcagttct caaggatgat cgagcagttc cttccagttt tttaattaat
    37321 caggccagtt atagataaat acttgatctt atctatatca ggacttctat attaagcaaa
    37381 aatttatgta caaaactaaa atcttcattc agttgtctcc ccgcttttta tacgattgta
    37441 ttaaaaacaa tagaagcctt tccaaattat gttactccag taaagatgga attatagttt
    37501 gacggaagaa aagcaagtat aacttttaaa aaaaactgat acattcgcat ctcctgcttc
    37561 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
    37621 ttattttgcg aattcggtga ttaattcccg attttgatat cgcacctgag ggaatcattt
    37681 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
    37741 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
    37801 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
    37861 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
    37921 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa taagaaatat
    37981 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
    38041 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacgg ctcgtttccg
    38101 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
    38161 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
    38221 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
    38281 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
    38341 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
    38401 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
    38461 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
    38521 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
    38581 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattccaaaa
    38641 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
    38701 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
    38761 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
    38821 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
    38881 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
    38941 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
    39001 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
    39061 caatggtttt acggtcgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
    39121 agacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
    39181 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
    39241 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
    39301 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
    39361 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt cccccatcat
    39421 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgcaaactt ttcaggataa
    39481 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
    39541 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
    39601 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
    39661 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
    39721 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
    39781 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
    39841 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
    39901 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
    39961 tgactcattg attttttcac gtaattgtcg tggtgtcaat gtcgtcgtat caatgatcac
    40021 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
    40081 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
    40141 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
    40201 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgtaaatcca ctcctaaagc
    40261 catttttgtg actttgcctg attctttgat taattcccag aattttggaa tcaatcgagg
    40321 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
    40381 ccctgcaccg ctcatacctg ttatgatgac taattgcaaa ttatctgtca taattacgaa
    40441 ctcctctcac attgtgcata gtaaaattat atcattccgg gcgtatcatt accagttttc
    40501 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
    40561 tttttttact tttccgatgc tgtatccaat gccttgcttc tttcagctag cgctcgttca
    40621 atcgtccgat ctgctaaaat agattgggca tcgatcactg gataatggtt atcttcagca
    40681 aattcatgca tcaatgacaa ttctgtgcaa cctaagataa ctttttcaca gtttaggcgc
    40741 tctaccgctt cttctaagat ttcgtaatat agctcttgat tcaaataatc cgattccttg
    40801 atctcatgat agatcagata attgattttt tcttgaagaa cagtatcagg aatcactgtt
    40861 tcgaatccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
    40921 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
    40981 ggcatatgaa ggataggaat atccgttgcc gcttgtaatt cttcaaaaaa gtagtgtgcg
    41041 gtgttacaag tcaacacaat gaagttcggc tgcaataaat tttgtttctc aatatcatcc
    41101 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
    41161 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
    41221 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
    41281 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
    41341 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgaccg gtctttttca
    41401 taaaacacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
    41461 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
    41521 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttaaa cactcgatct
    41581 tctgtgacga aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
    41641 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
    41701 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
    41761 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
    41821 tctaacagtg gatgaccaag acacatcatc cgaacttgat gatcttcatc tacatacgca
    41881 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
    41941 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
    42001 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
    42061 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
    42121 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
    42181 aagcttactt tattgatcag tctttcaaat aaagaataat caatatatgg acagataaaa
    42241 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
    42301 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
    42361 tcgataaaca cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
    42421 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
    42481 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
    42541 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
    42601 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaactcctc
    42661 cgattgctca attctttttt gaacggattg aacttatagg aagtttttgt ctataccaat
    42721 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
    42781 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
    42841 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
    42901 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
    42961 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
    43021 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
    43081 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
    43141 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
    43201 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
    43261 ttctacagca tcttctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
    43321 cacttctaat gtttcagagt tatatcgttt gccatgacat acttcacaag gaacatagac
    43381 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
    43441 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
    43501 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
    43561 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
    43621 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
    43681 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
    43741 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
    43801 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
    43861 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
    43921 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcag
    43981 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
    44041 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
    44101 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
    44161 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
    44221 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
    44281 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
    44341 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
    44401 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
    44461 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
    44521 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
    44581 gaaaagatca tctgtcccat tcaagatgat atcctgatgc tcttccggta attcttcgaa
    44641 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
    44701 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
    44761 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
    44821 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
    44881 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
    44941 cagagcatag ccgtctgcca atcgcagagc cgcctctaaa gaatcaaata gacgagaacg
    45001 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
    45061 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
    45121 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
    45181 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
    45241 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
    45301 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
    45361 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
    45421 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
    45481 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
    45541 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
    45601 gttatgggca cgtgcaccgt gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    45661 tgaagctttt aattctaaaa tcatatctcg cacattagcg gctgtttcaa aatccaatgc
    45721 tttcgccgca tttttcattt ctttttctaa tttcatcaat aacgtatctt tttcttcttt
    45781 cgtcatttct tcatacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    45841 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    45901 attgtacttc tgctgaatcg tacggcgtct tgatgtttca tccatcgcta gacgcataga
    45961 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    46021 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    46081 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    46141 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    46201 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    46261 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    46321 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    46381 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    46441 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    46501 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    46561 ttttctcgct cggtcaccat tatacattcc tctgacttga ggcatggtta cgtgcgattc
    46621 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    46681 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    46741 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    46801 gttttcattt cgcaagacag ttaaacgctg ttctaattcc gctttgatat tcgctacggc
    46861 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ccacgtgttc
    46921 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    46981 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    47041 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    47101 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    47161 tacttgtttt tggtactcaa aaggcgaacc taatccaaaa atacatgaaa cggatgcaat
    47221 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    47281 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    47341 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    47401 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa ttagtgttgg
    47461 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    47521 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    47581 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    47641 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    47701 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    47761 acttttttat cttattatgc atgttacgtt ttataacata aaatgttaga aactcgcatt
    47821 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    47881 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    47941 ttcttaatga caggacttgt gacacttgcg tttggacatg ttgcacaagc tgacaacact
    48001 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    48061 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    48121 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    48181 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    48241 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    48301 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    48361 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    48421 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    48481 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    48541 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    48601 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    48661 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    48721 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    48781 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    48841 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    48901 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    48961 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    49021 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    49081 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    49141 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    49201 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    49261 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    49321 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    49381 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    49441 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtgtcca tcaacgaagg
    49501 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacatttt tgcgttgctt
    49561 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    49621 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc agcactttaa
    49681 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    49741 agaatctaga gaagaagcag agaaaaaagc aatcaaattg ctgcagacag ttggtctaga
    49801 agataaaaaa gatatgtatc ctgaaatgct ttccggtgga caaaagcagc gtgtggctat
    49861 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta catctgcact
    49921 cgaccccgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    49981 gacgatggtt atcgttacgc acgaaatggg cttcgctaaa gaagtggcca atcgtgtcat
    50041 gttcattgac gacggaaact ttttagaaga cggaacgcct caacaaatct ttgaaaatcc
    50101 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaat aaaaaccaaa
    50161 aatgcccggt cgcttcatga cgaccgggca tttttagttt cttgtttttt cacttaactg
    50221 taccagccgc atcgcttgtt ctcctgcaca aacaagcaat cgctctacct gttccatcgc
    50281 ataagaaagt accatcggtt cattgacgat atcaagtaca tagtcgatac caccttcaga
    50341 aactatgatg attatcttat tctaaagctg gcttttttgt tggtacaaac atgacaacta
    50401 caaaaaaacc aggcgaacgt atgattgttc gtctggtttt taattattaa tgacttagcg
    50461 tttttactag aaatagaaaa tttgggcaag tctactttat atttttacta gaaaaactac
    50521 ttccgctttt tcccgccaaa agcatcttta aacttatcga agaaaccgtc ttcttgctgt
    50581 tcttcaactt tgatgccgcc agcttcagcg aatgcacgta atgcttctct ttgttgttca
    50641 tttagatttt tcggtgtgat cagttttact ttgacatgtt ggtcgcctgt tgcaccacca
    50701 cgtaacttcg gagcgccttt tccacgtaaa cggaagttcg tacctgtctg tgttccagca
    50761 gggatcttca atttcacatc tccatggaca gttggtactt ggacttcatc ccccaaagct
    50821 gcttgtacaa aacttaaagg caattcatag taaatttcag aaccttcacg atcaaagata
    50881 tcactttctt ctacacgaaa aaccacatac aaatcaccaa atggtccgcc gttttctcca
    50941 gcttctcctt gaccagctaa acgcatttgt tgtccttctt ctacaccagc tggtacattc
    51001 actttaactg aatgtgcttt cttctcatgt cctgagccat gacaggttgg acaaggttct
    51061 ttgatttctt tccctgtgcc atgacaaaca tcacaagttt gacggctcat cactcgtcca
    51121 agtggcgttt ggcgttctac attgatcgta cctgcaccat gacatttatg acaagtagtt
    51181 ggttgtgtgc ctggttttgc accgtttcca ccacaagtat gacagatttc ttcccgatta
    51241 tacttgattt ctttttctac accaaaaatc gcttcttcaa aagacaagtc gaccgtatat
    51301 tgcaaatcag caccttgacg aggcgcattt ggatcgactg accgaccgcc tcctccaaag
    51361 aaagagtcga agatatcttc aaaaccaccg aagccgccac cagagaagcc gccgaatcca
    51421 ccaaatccgc caccagctcc accagcaccg taatttggat ctgtgcctgc atgcccgtat
    51481 tggtcgtatg cagcgcgttt ttgcgggtca cttaaaatct catatgcttc tgatacttct
    51541 ttgaattttt cttccgcatc aggttcttta ttgatgtcag gatggtattt tttcgaaagc
    51601 ttacgataag ctttctttat ttcatcttct gatgctcctt ttgagagccc taagacttca
    51661 taataatcac gttttgttgc cataggcttt cctcctattg gttctcatca ttttcacgtc
    51721 gcttgttatc atatcatatt ttgtttgaaa caaaaaccga tacttcaaac tatttttcaa
    51781 aagaaaaagc caaagtagca actttggcct tctctcgaaa ttcagtgaac tgattattta
    51841 tcgtcgccat cgacttcttc aaaatcagca tcaacgacat catctgctcc gccttgagct
    51901 gcttctggat tttcttgagc ttgttgttgt gcagcttgtt cgtatagttt aacagtcaag
    51961 ttttgaacga tttcgttcaa tgcatcgcgt ttagttttca tttcctcgat gttgtttgct
    52021 tcaacagcgg cttttaattc gtcacgagct gtttctgctt ttttcacttc ttcttcgtcc
    52081 actttgcctt ctaattcttt caatgttttg tccacagaga atagcaatgc gtctacatca
    52141 ttacgtaggt caacttcctc tttacgagct ttatctgctt cagcgtttgc ttctgcatct
    52201 ttcaccatac gttcgatttc ttcgtctgtt agacctgaag aagatttgat cgtgattttt
    52261 tgttcttttt gtgtacctag atctttcgca gatacattta caatcccgtt tttatcaata
    52321 tcgaatgtta cttcgatttg tggaatacca cgaggagctg ctggaatatc tgtcaattgg
    52381 aatcttccta gagttttgtt gtcagcagcc attgggcgtt caccttgtaa tacatggatg
    52441 tctactgctg gttgattatc tgccgcagtt gagaatactt gtgatttact tgttggaatc
    52501 gttgtattgc ggtcaatcaa tttagtgaac actccaccca ttgtttcgat acctaatgac
    52561 aatggtgtaa cgtcaagtaa aacaacatct ttcacatcac cagtgatcac gccaccttgg
    52621 atagcagcac ccatagcaac tacttcatca gggttaactg atttgtttgg ttcttttcct
    52681 gtttctttac gtactgcttc tacaactgca gggatacgag tagatccacc gactaaaata
    52741 acttcgtcga tttctgattg tgacagacct gcatctttta acgcttgacg tactggtact
    52801 tttgtacgtt ctactaagtc agctgttaat tcatcaaatt ttgcacgtgt caatgtcatt
    52861 tccaaatgca atggtccaga ttctcctgct gtgataaatg gcaagctgat ttgtgtgctt
    52921 gatacgccag ataaatcttt tttcgctttt tcagcagcgt ctttcaagcg ttgtaaagcc
    52981 attttgtctt gagacaagtc aatgctgttt tcttttttga attctgctac catgtagtcg
    53041 atgattttgt tatcaaagtc gtccccacct agatggttgt cgccagctgt tgacaataca
    53101 tcaaagacac cgtctcctag ttcaaggata gatacgtcaa aagtaccgcc accaaggtcg
    53161 aatactaaga ttttttcgtc gcgatctgtt ttatctaaac cataggcaag agcagctgca
    53221 gttggttcat tgacgatacg ttctacttct agaccagcga tcttaccagc atcttttgtt
    53281 gcttgacgtt gtgcatcatt aaagtaagct ggcacagtga taactgcttt ttcgactttt
    53341 tcacctaaat agtcttctgc gaatcctttg atatattgaa ggatcattgc tgagatttct
    53401 tgtggtgtat atgatttacc ttctacatct actttgtaac ctgcttcacc gatatggcgt
    53461 ttgattgatg aaatcgtatt tgggtttgtc acagcttgac gttttgcaac ttcccctact
    53521 tggatttctc catttttgaa tgatacaaca gaaggtgttg tacggtttcc ttctgggtta
    53581 gcgatgattt ttgcttcgtt tccttccaat actgctactg cagagttagt cgtacctaag
    53641 tcaataccga taattttact cataattaac gtctccttct ttaattgaaa gtgtaagttt
    53701 tatatccgca caattattgt gcaacaatga ccatagttgg tcttaacacg cgatcatgta
    53761 atttgtagcc ttcttgtagt acttctacaa tcgtatcggc tggtgtatct tcagtcgctg
    53821 gaacagtttg tactgcttga tgaagattag gatcaaaggc ttctccttta gcagggattt
    53881 tttcaattcc ttcttcttcc agtgcgttac gcaaactttc caagaccatt tccacgcctt
    53941 ttttcaaacc tgccccttga tcatctgaca cttctgtggc taatgcacgt tccaggttgt
    54001 caattgatgg aagtaatttt ttggctaaat cttgtgaacg gtatttttgt aattgctcac
    54061 gctcattttt tcctcgattt gccatatttg cgatttcagc acgagcccgc aagtatttat
    54121 cttccatttc ttctaactca gcttttaatt tcgctgtttc gaattcttcc gcttcagctt
    54181 ctgaaatacc cgaatcttct gcagcttcga catcgatttc cggttctggc tgagcatctg
    54241 tcatttcttt atctagttct tcttgatttt ctttcacgat acagtcttcc tttcattatt
    54301 cagtcagctg tttgattgct cttactaaga aagagagaac gatcagctgc aaatagcttc
    54361 gttattcaca ttacgagttt gacaagtcaa gcgagcggta gtaatcagca agtttagctg
    54421 ctagttctct tcgataaaca tcgactagac cgaacatccg agaataaggc atactagtag
    54481 gccctaacaa ggctattgta cctcttccat gaccatctat ctcgtaactt gcttgaatca
    54541 tactcatatt ctgcaataaa tcattgccta attcagcacc aatcttgata tgaatattgc
    54601 tatccatcgg agtgatcatt tgtgtaagtc cgtctgagtc tttcataaaa gaaaacatcg
    54661 atttgaactg atcaagatct tgacggggct cataatccaa gagattcatt tgtccactga
    54721 cataaacctt ttcttcaaaa acatgaccaa gaacggtgtc aaataactga gacatccctt
    54781 ctgtcgtctg gaaatattta tgaagaatca tcggaatctc cgtacgaagt ttatggtaca
    54841 ccgtcatcag aggatctccg actagacggt cgtttacaat ctgtaccatt ttttctagtt
    54901 cctgacttcc catatattcg ggaagagtga acacttggct ttctacattc cccatatctg
    54961 ttacgacgat agcaataatc tgtcgattat tcaagggtac gatacgaaag ccagtcagtc
    55021 ggcggtcttt tatttcaggt cccaatgaaa aagtcgtata gcttgtcagc tcagataata
    55081 tctcagcaga ttgcttaata atctcattga tttcatgaaa ttctctgcct agagactgac
    55141 gaatcagcag caaatcatct tctgctacgc gagcaggttt taacaaatga tccacgtaat
    55201 aacgatagcc taaagcagat ggaatccgcc cagaagaaga gtgagtcttc aacagcaatc
    55261 cttcatcttc taatgctttc atatcattgc gaatcgttgc tgagctggcc ttgactccct
    55321 cagacattaa tgttttggaa ccaacgggca cgccactact cgtatagtgt tggatgatca
    55381 gacgtaaaat gtcgttttgt cgctttgtta acatcttcct cacctctcat tagcactcat
    55441 atattctaag tgctaattca cttataaata tagcaagaag cccttctcct gtcaagagaa
    55501 agactccatt ttttagcact ctaaacacaa gagtgctaat tctaaataat tgatgtaaat
    55561 ccagttatat caatacttca atacctcatt gtcaaacttt ctaaactttt tcttttcaag
    55621 tttcgataaa aaacaaatat tcttcaaact atttttcaaa taaaaagcgc tcaaacacat
    55681 tgttccccaa aaaagtccct cttggtgtca aataaacacg gtcttcttca ttaacaagta
    55741 acccttcttg ctctaattcc cttagcacat caccgtacac cgattcaatt gttttttgat
    55801 agcgatcata gaaatgtttt ttagtaatcc ctgttttttt tcttagtcct aagaacattt
    55861 cttcttctat ttgatttttt cgtgtcaatt tttcttcttc caataccggg cgttcatttg
    55921 ctcgtaatgg gcgtaaatag tgttggattg gtcctttgtt gcggtaacga atatctccaa
    55981 gataaccgct agcaccagct ccaaacccaa aatagtggtc attgttccag tacatgaggt
    56041 tatgttgaga ttcatgtccg gagagcccaa agttacttat ttcatattgg tgacgtccat
    56101 gcttttccat tgcttcaatc gtctcttcaa acattctggt ttccgtttcc tgatcaggca
    56161 gttcgagtct tccttgtcgt acccagttca tgaacattgt tttgttttcg aggatcaatg
    56221 agtacaaaga atagtgaggc agatccaaag ccaaagcttt ttccaaagta tcccgatttc
    56281 cttctagtgt ttgtcccggt aatgcataaa tcaaatcgat gcttacattg gtaaaatttt
    56341 ctgcttctaa aaattgcatt gtttgataca catcttctgc agtatgttta cgtccaattt
    56401 ttttcaataa gcgattgtca aatgtctgca ctcccatgga taaacgattg acgccatagt
    56461 ttttcatcac ttgaagtttt tcacgggtca aatcaccagg attcgcttct acagtaaact
    56521 cattaccatt ttgaaaaggc aggatctctc tagcacctga taatagtcga tcaagttgtt
    56581 tagcagataa agaagttggt gttccgcctc ctacataaag tgtttccaaa ttcgctgtag
    56641 gatgactttc cagcattaat ctcatttcat tcagcagcat ttccacatac tcatctactg
    56701 gctgcccttc taaaaaaact ttattaaagt cacagtaata gcagatatgc tcgcaaaatg
    56761 ggatatgaat gtacgcagaa accttgtttt ctgcgggatt tattgtttct atcattgaaa
    56821 ttctttctcc ttacgtcgaa aagtcgtgcc tgttttcgac cttcttaaaa tcgcgttcaa
    56881 gcaccaactc attgaaataa gccgcatatt tagaatcaag gaaacctagc tctaaaaatg
    56941 cttgcttatt gtcatcggag ctacacggtg cttttacagc ctctcgataa acggtaatcg
    57001 caaagctgac cttcggcatt aagtcaaaat ctgcaaaaat atgaaaagct attttcacag
    57061 attcctcctt aagtgctcag accacaacgc tttgcttaca acctctcata tacgcatact
    57121 aaacgtattt ggcgaacaaa tccactaaaa aatccaagaa tcgacttctt ggatgatttt
    57181 tttacactca tgattcttcc taaacaattt tgtccttatt ttattcataa aaaaatctag
    57241 tcaaatctct cacttcaaga gttttaacta gattccaatt attatttttt tgtaaaaata
    57301 aacagtctct taatcataga catttcttcg gtgccctact tgaatagcga taacaacgaa
    57361 ttgattatct tctatctcta ccaatacacg tatttgccaa tcagagctgc ttctgaattt
    57421 cgggcgtgaa ttttaaacga caggtcattc cagcccacca aattcattaa ggattcttcc
    57481 atgaatactg ttgttttccc acttcttatc caatgtttat gggcaatttc agccgtttga
    57541 cgattgtatt catcttctag ttgttccatc gaatagtttt ttagaagttc agataaagta
    57601 atcccataaa attcagccat ataagaaagc cattcttttt tggcgtcact tacacgaacc
    57661 gtaatcatag ccctataatt gcctctctta aagaatctca tgcatttcct gatgtgattt
    57721 tagaaaaatt tacttgctaa aaaactgtga aaatgtagga gctagcatcc ttgtagtaaa
    57781 tgatcgagct ctttattata cattaaaaaa gttcagaaat tttgatgaag tagccaacta
    57841 ctttttcatg agtaaagcaa cactagaaaa agaatcctcc agtacttaga atttactgga
    57901 ggatgtactt ttgaagaagc ctataggtta tttaaaaaat attactacag gaaggaacga
    57961 gaattacttc gttacttata atagaactta gtcttatata gaaggcatag ctcacattag
    58021 cttatttgtc ctataaaaat aaattacggt attttagaaa agctattttc tcttttttca
    58081 acgatcttca gcaatttttc tttatcgtca ggtaactcaa gttcatgaat tctagcatga
    58141 caattgggac ataacgcgat acagttttca atcacatctt ttccaccttg cgacaaatat
    58201 tctatatgat gacaatgtaa ataaggtaca ccgtctttta taaatggccc tttttcttgg
    58261 caaagttgac aaataccttt tgcaagtcgt ttaacatatt cagatacgaa gggattacgt
    58321 ttatatattt ttgtttttga gaagcaaaac tcctcttcgt taacatattt tgcagccatt
    58381 tttttattat aattactaac ttttcttgct tcttcctcta atttagcatt agataaatta
    58441 cgaatatgtc tagtttgatt ttcttcctgg ttatatatct ttatcttcaa tcaattgctc
    58501 ttgatttatt aaagctaatg gaaatttata tacttttctg ctgttgcccg aactatcttt
    58561 ttcattaaca gtatatattt gtcctgctaa atatacttct cccagatatg tgtgttcttt
    58621 tggtttaaat gtttcaaata aatgaatctt tacaaaatta ctttttgaat tggctaaaac
    58681 tttattttga ttcttatcca atacttgatc cccttttagc cccataccgg tatattgtaa
    58741 aataccattt aaccacttat ctttataaac attacttcct gtttgatcac taaacagtac
    58801 aagagtatta gtttgatgag atcttctcat tccaccctgt ttggaacatt taaacttctc
    58861 tgaaatttct ttgttagtat atactctacc aacttctaac tcacctaata tgtttttaga
    58921 ccaattttct cgccatgtaa taatcttatc aagattaaac atttctccct cttttggcat
    58981 gccatttcta attaaattag ctaatacacc agtagaaata tctaattttt ttagtaattc
    59041 tttcttagta atcaatg
//
LOCUS       DADQCX010000004        57845 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.004, whole genome shotgun sequence.
ACCESSION   DADQCX010000004 DADQCX010000000
VERSION     DADQCX010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 57845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57845
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.004"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            99..284
                     /locus_tag="J8R83_000188"
     CDS             99..284
                     /locus_tag="J8R83_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAZ9573354.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            351..746
                     /locus_tag="J8R83_000189"
     CDS             351..746
                     /locus_tag="J8R83_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAZ9573355.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            736..1113
                     /locus_tag="J8R83_000190"
     CDS             736..1113
                     /locus_tag="J8R83_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573356.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            1114..1509
                     /locus_tag="J8R83_000191"
     CDS             1114..1509
                     /locus_tag="J8R83_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573357.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
     gene            complement(1816..2214)
                     /locus_tag="J8R83_000192"
     CDS             complement(1816..2214)
                     /locus_tag="J8R83_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAZ9573358.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(2406..3173)
                     /locus_tag="J8R83_000193"
     CDS             complement(2406..3173)
                     /locus_tag="J8R83_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9573359.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            complement(3208..4431)
                     /locus_tag="J8R83_000194"
     CDS             complement(3208..4431)
                     /locus_tag="J8R83_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAZ9573360.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLENHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            5412..6215
                     /locus_tag="J8R83_000195"
     CDS             5412..6215
                     /locus_tag="J8R83_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9573361.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            6800..7255
                     /locus_tag="J8R83_000196"
     CDS             6800..7255
                     /locus_tag="J8R83_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573362.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            7374..8432
                     /locus_tag="J8R83_000197"
     CDS             7374..8432
                     /locus_tag="J8R83_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAZ9573363.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            8474..10423
                     /locus_tag="J8R83_000198"
     CDS             8474..10423
                     /locus_tag="J8R83_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAZ9573364.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            10426..14067
                     /locus_tag="J8R83_000199"
     CDS             10426..14067
                     /locus_tag="J8R83_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573365.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            14467..14805
                     /locus_tag="J8R83_000200"
     CDS             14467..14805
                     /locus_tag="J8R83_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573366.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            14915..15136
                     /locus_tag="J8R83_000201"
     CDS             14915..15136
                     /locus_tag="J8R83_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573367.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            15156..17312
                     /locus_tag="J8R83_000202"
     CDS             15156..17312
                     /locus_tag="J8R83_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573368.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            17324..17557
                     /locus_tag="J8R83_000203"
     CDS             17324..17557
                     /locus_tag="J8R83_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9573369.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            17547..18413
                     /locus_tag="J8R83_000204"
     CDS             17547..18413
                     /locus_tag="J8R83_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573370.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            18428..20398
                     /locus_tag="J8R83_000205"
     CDS             18428..20398
                     /locus_tag="J8R83_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573371.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            20565..20792
                     /locus_tag="J8R83_000206"
     CDS             20565..20792
                     /locus_tag="J8R83_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573372.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
     gene            20789..21283
                     /locus_tag="J8R83_000207"
     CDS             20789..21283
                     /locus_tag="J8R83_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573373.1"
                     /translation="MNKLPEKNRVFRLKGDLSQFKIDENGQFFVWMRHEHCWCNPFVL
                     KKENEIRTKIANGEWDYLFRWEDESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQN
                     IDIDAIECLKEVDQKYEEEPYYLLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDR
                     KSSI"
     gene            21458..21793
                     /locus_tag="J8R83_000208"
     CDS             21458..21793
                     /locus_tag="J8R83_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573374.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(22050..23633)
                     /locus_tag="J8R83_000209"
     CDS             complement(22050..23633)
                     /locus_tag="J8R83_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573375.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRNRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            23755..24339
                     /locus_tag="J8R83_000210"
     CDS             23755..24339
                     /locus_tag="J8R83_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573376.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            24350..24595
                     /locus_tag="J8R83_000211"
     CDS             24350..24595
                     /locus_tag="J8R83_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573377.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            24601..25323
                     /locus_tag="J8R83_000212"
     CDS             24601..25323
                     /locus_tag="J8R83_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573378.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSADNNKDTKSSSTVVTKN
                     SSTSASTTISSMTENNAEKYQKYEDINKGQKPEEVYTDFINTVKNDEDYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYHAVAVDITDGV
                     PEWIQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            25454..26197
                     /locus_tag="J8R83_000213"
     CDS             25454..26197
                     /locus_tag="J8R83_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573379.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKAKSIRELKTEVEKIRLGLTREEISRLSENSSFVIQKEKEKHLLHRELIIEKYYDV
                     DLPDQLRIIDEFSEKKWKSEIYPSLIQYKASGKPMYNYTGFLNYTQYKYAFRKLKGIK
                     QADIALYEMKKMDRLKLIQELVQNTWNQAIVELEKENGKILTNEYLIVNEIEELIGLF
                     SCENGEVFLKSSPIYSILDSPYQFIQVRR"
     gene            26203..26568
                     /locus_tag="J8R83_000214"
     CDS             26203..26568
                     /locus_tag="J8R83_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573380.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDQQFNQTHHNIILLVDQAKRRLEKAEYELLDQGIICLDKGIRRYYSAELKKQ
                     NVDRHALKHEILELIMQRI"
     gene            26584..27114
                     /locus_tag="J8R83_000215"
     CDS             26584..27114
                     /locus_tag="J8R83_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573381.1"
                     /translation="MSQNISAVKQLIEKDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAEEKSSILEISQ
                     NDKAIQVKCVDPTGKIIVGFDIERKSKIDFITQLTKINNLNILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFSNA"
     gene            27276..27644
                     /locus_tag="J8R83_000216"
     CDS             27276..27644
                     /locus_tag="J8R83_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573382.1"
                     /translation="MWNNKLKTGLLLIVISCAMMVGMIIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSNLMMKKV
                     RKLAQNYLEEKEGNSPIDKN"
     gene            27835..28095
                     /locus_tag="J8R83_000217"
     CDS             27835..28095
                     /locus_tag="J8R83_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573383.1"
                     /translation="MAYENLQLVVAEVSGDIYLTKVKDGIMDTNYRRVATDDVLSSST
                     EWFRKNEESAVHFEGIDGNIHSLFYTKDKEKAKKILDILKGR"
     gene            28713..29513
                     /locus_tag="J8R83_000218"
     CDS             28713..29513
                     /locus_tag="J8R83_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573384.1"
                     /translation="MSKDLRELKLRKKQYNQYFSSLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSRSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            29550..29732
                     /locus_tag="J8R83_000219"
     CDS             29550..29732
                     /locus_tag="J8R83_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573385.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENVEDLRLIGE"
     gene            29922..30209
                     /locus_tag="J8R83_000220"
     CDS             29922..30209
                     /locus_tag="J8R83_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573386.1"
                     /translation="MVEVEFGSKEWFEELNSMIKFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            30300..30539
                     /locus_tag="J8R83_000221"
     CDS             30300..30539
                     /locus_tag="J8R83_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573387.1"
                     /translation="MKEIEGIKKRNQERLELLNENRNRMFSYYESMRCLNKSRSEIIE
                     SSKYKQLMEERVSLIQEIETESIFPDHSPKVRFYN"
     gene            30667..30996
                     /locus_tag="J8R83_000222"
     CDS             30667..30996
                     /locus_tag="J8R83_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573388.1"
                     /translation="MKLEGSLQNRMMEGSTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELVKTKNGWKVLKEDIHFYIGDRE
                     KYYDPSF"
     gene            31049..31880
                     /locus_tag="J8R83_000223"
                     /pseudo
     CDS             31049..31880
                     /locus_tag="J8R83_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            31895..32212
                     /locus_tag="J8R83_000224"
     CDS             31895..32212
                     /locus_tag="J8R83_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573389.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            32215..32447
                     /locus_tag="J8R83_000225"
                     /pseudo
     CDS             32215..32447
                     /locus_tag="J8R83_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(32562..33038)
                     /locus_tag="J8R83_000226"
     CDS             complement(32562..33038)
                     /locus_tag="J8R83_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573390.1"
                     /translation="MTDKTSDLPKLDPKISQVKSKKDGKTKNAVKETSSLLLDIPMSS
                     FDEILDANTDETSVKIASHVGMNSQNDYFYNLLNSLRKLEDKKNQVIASKAPDLTTDL
                     DAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            33164..34495
                     /locus_tag="J8R83_000227"
     CDS             33164..34495
                     /locus_tag="J8R83_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAZ9573391.1"
                     /translation="MVQFTGIAMSVITINPQVLHADGIATYDAQFNCTTEGSGSGTDS
                     DGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRTVEGYY
                     GDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMFKG
                     DGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMKSK
                     GMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEGKI
                     NGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFQGELQGQCTELTWAYMSQL
                     YDGNQPTLGNGGYVWESYKSAGAKVTNKPIVGYAFSALDGWLWAVGSAGHTGVVIAVF
                     DDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            34520..35047
                     /locus_tag="J8R83_000228"
     CDS             34520..35047
                     /locus_tag="J8R83_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573392.1"
                     /translation="MNSKTKDAIIISLLSGMLLAMLVGILYFNKQNQDIEAEKHSVQI
                     ENELTFFKEVKPNEVDGLQRDLENDIQEMFKGSDRSKFANQSGEEFLRKLFIVTGKPP
                     VTNESSEQEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            35034..35597
                     /locus_tag="J8R83_000229"
     CDS             35034..35597
                     /locus_tag="J8R83_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573393.1"
                     /translation="MQNHEITTAKKAIGILSIILILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            36015..36752
                     /locus_tag="J8R83_000230"
     CDS             36015..36752
                     /locus_tag="J8R83_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573394.1"
                     /translation="MADRKLEKLLEETWDPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENRGTWDFWANLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISEQDGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVNITNRLDYDSWADIALEKYIYSTLKEFIENRMNIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(36769..37185)
                     /locus_tag="J8R83_000231"
     CDS             complement(36769..37185)
                     /locus_tag="J8R83_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573395.1"
                     /translation="MNKKRKLSVLITLVSMLAILSGILSIKIFNQINTSANTKNEIVI
                     ENTSNSKEISTTKNKDKSDETTTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKDEELYSFVK"
     gene            37578..38825
                     /locus_tag="J8R83_000232"
     CDS             37578..38825
                     /locus_tag="J8R83_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573396.1"
                     /translation="MNMKKNSLAMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNINK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSNPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            39095..41485
                     /locus_tag="J8R83_000233"
     CDS             39095..41485
                     /locus_tag="J8R83_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAZ9573397.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDEQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            41534..43369
                     /locus_tag="J8R83_000234"
     CDS             41534..43369
                     /locus_tag="J8R83_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAZ9573398.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            43444..44301
                     /locus_tag="J8R83_000235"
     CDS             43444..44301
                     /locus_tag="J8R83_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9573399.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNVNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            44291..45370
                     /locus_tag="J8R83_000236"
     CDS             44291..45370
                     /locus_tag="J8R83_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9573400.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDGGSFDIGEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQNSTLTDIPDL
                     DMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDSESVSDKTETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVIGALASLKVLILLIKEFRKA"
     gene            45709..46509
                     /locus_tag="J8R83_000237"
     CDS             45709..46509
                     /locus_tag="J8R83_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573401.1"
                     /translation="MVGISKTALDSLAKLFSSRFDSAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            46597..47403
                     /locus_tag="J8R83_000238"
     CDS             46597..47403
                     /locus_tag="J8R83_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573402.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            47635..48504
                     /locus_tag="J8R83_000239"
     CDS             47635..48504
                     /locus_tag="J8R83_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAZ9573403.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            48524..48871
                     /locus_tag="J8R83_000240"
     CDS             48524..48871
                     /locus_tag="J8R83_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573404.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            48884..50146
                     /locus_tag="J8R83_000241"
     CDS             48884..50146
                     /locus_tag="J8R83_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573405.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            50226..51602
                     /locus_tag="J8R83_000242"
     CDS             50226..51602
                     /locus_tag="J8R83_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAZ9573406.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKANQGAKSLEKLQQEKLEKLEKALSS
                     STSETQSSKGIDNGQSITTKNKPKNSNSNLSVNVVITTDKSEKKQVNGTTSPIMQKMI
                     KAKKQVQK"
     gene            51599..52228
                     /locus_tag="J8R83_000243"
     CDS             51599..52228
                     /locus_tag="J8R83_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573407.1"
                     /translation="MIIISSFLRWLTPYKYTDEIVEKRAKKKVKKTMLTPKEMLDRGI
                     LGVKVLEVNQPFELDNARDRLLRAEVDVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLKPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSSQNRVQINKFEKKVRK
                     FNDRKIILWFANIQKQPDGTAKWEAVIFDEDGKKVMSEVWHDKAKFVWQ"
     gene            52240..52710
                     /locus_tag="J8R83_000244"
     CDS             52240..52710
                     /locus_tag="J8R83_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573408.1"
                     /translation="MLTNLKLYREGFNEKVSIGESIEYLGKKYIIIRILEIKKLYFSK
                     YNNLAVRVLVQKVGNPSDYRSDYHNYKTESSVIKRYNQSKNDERIFKVGEIIISKYGI
                     AYEIVSIKKFYYEFVDLVVEYSVRLIVPWSKEEINEALKHERKSTFKVLEGEKK"
     gene            52707..53189
                     /locus_tag="J8R83_000245"
     CDS             52707..53189
                     /locus_tag="J8R83_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573409.1"
                     /translation="MKTDLTRQAEKCLWHETNRMGVFGCFEVTIGWDGSERVDYITYS
                     VDNTVRCYEIKVTLADLKSKAKQTFIGDYNYLVVTSDLWEKMQQDDKLMRKYYYQGVY
                     VFNEKYPSIISVKKARKQKVSLGTRSTVLESMVRSMNREVKKLYKVKPFWEIAEVEKG
                     "
     gene            53186..53848
                     /locus_tag="J8R83_000246"
     CDS             53186..53848
                     /locus_tag="J8R83_000246"
                     /inference="COORDINATES: protein motif:HMM:NF019467.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290663.1,RefSeq:WP_002351343.1,
                     RefSeq:WP_010747081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAZ9573410.1"
                     /translation="MIQTFAKMSRSAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVELDEPKKSVDVPENVAELLDYYRNSSDVDLLALILTFHDWYYCQNEDTQHDKHD
                     KAVDWLIENPEKFMRAWLDGYDSKKKPLESNEETYLTAEQYDYARKTGDWESGKTFNH
                     RKDQPKISFSDIAAIIEGIYYGQADEEIFSIQDLLEFLNKNKDSFVELTDYEEDTANG
                     KL"
     gene            53835..54203
                     /locus_tag="J8R83_000247"
     CDS             53835..54203
                     /locus_tag="J8R83_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAZ9573411.1"
                     /translation="MENYDPNMRWGTHTLKVSFQRWDYKGFVTFRKAGNCKGLDVLAL
                     DEDYLYDHPLTDNPIGFGLLPEDDEGNEWFKMILTNDKGDQLFVEDTWSYLSEYIVSI
                     KIIDFVADKEKEIGEGKSNY"
     gene            54284..54730
                     /locus_tag="J8R83_000248"
     CDS             54284..54730
                     /locus_tag="J8R83_000248"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573412.1"
                     /translation="MIVSAVTIYWLGNQQNSLIVDLGELKVGLRMTRWLLLAQTVGLA
                     ILTWICVEKITSNNNQEIVESTNLRITEQAIEKQKDKEKKEIMSIYLSSGASFFHEID
                     SMKLSSQEIIDRWKNMPLGGELIVEDSDGWSAYKKDEIVAITILFE"
     gene            55382..55435
                     /locus_tag="J8R83_000249"
                     /pseudo
     CDS             55382..55435
                     /locus_tag="J8R83_000249"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55439..56038
                     /locus_tag="J8R83_000250"
     CDS             55439..56038
                     /locus_tag="J8R83_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAZ9573413.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLQSNIVSMGLSGGIFGWIALFAIAYIHFDSKEHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            56054..56530
                     /locus_tag="J8R83_000251"
     CDS             56054..56530
                     /locus_tag="J8R83_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573414.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            56547..57449
                     /locus_tag="J8R83_000252"
     CDS             56547..57449
                     /locus_tag="J8R83_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573415.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            57522..57713
                     /locus_tag="J8R83_000253"
     CDS             57522..57713
                     /locus_tag="J8R83_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573416.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
BASE COUNT        21499 a         8024 c        11185 g        17137 t
ORIGIN      
        1 gaaaaaatta actagcacca cgggttaaaa catcctcttt ttctattgat tccatacaca
       61 acaatgtgta taatagattt tgtaaaggga gggtagctat gcctaagaca gcaagagaaa
      121 ttgtaaaaat tctcaaatct aacggcttca aaaagactgg acaaactggc agtcatgcaa
      181 aattttataa ttccaagact aaaagaacgg tcgttgttcc gatccacaat ggtgatgtac
      241 cactaggaac agaagctaat atctggaagc aagcagggct ttaacagcct tgccttccta
      301 tttggtatta ggcatactat cctctcttac actagaaaag gagcgaggaa atgaagacaa
      361 aaaatatttt ttatccggca atcttcgaga aagaaggaga agcttataac atcgttttcc
      421 ctgacttacc ggaaatatct acctttggaa atagtcttga agaagcatat ttaaacgcta
      481 aggatgcttt aggattagcg ctatatagtg taccagatgc agaatttcct aaaccatcag
      541 cagtggaaga attaactttg aaagccaacc aagtggtagt aatcatccaa ctaaacatta
      601 aacttttccg aagaagctta aatacaaaaa caattagaaa aaatgttagt gttccggaat
      661 ggttagttct tttagggaag gagaaaaaca taaacttctc tcaactactt caaaaagcac
      721 tagaagaaga gttgcttgaa aagtaaaaag gagaccgaac ctatgaaagc tacacactta
      781 aactatttct ctcgaacgtt aatcaataat ctattaaaag atacaactgg cattagcgtt
      841 agtaccaaac actttgccaa tgatctaatt atttttgagg ataataactt gcgaattgag
      901 atgtttattg aacaggcaac ccctaactca atacctgaat tctgctatac gcacactgaa
      961 aaaatgaaac atgcaaaatc agttaaagat gttgaagcat taagtgaatc actaacgaac
     1021 gctttaaacc tcgttaagaa ggcaaaattg ttatttgaat ttcaaaccga ctaccacaat
     1081 gagttgcttg ctcaatctga aattttagat taattgaaac aggagaagag aaagatgaaa
     1141 caaacacaaa cagaaaccgt taacgatacg cttgctgatc aattagcagg ttattataaa
     1201 ttatttgaga tgggtaaagc acagcgcttg atccactatc tttggaaata caaaattttg
     1261 tttctttttt gggaatcaac actaacattc tcagttcttt tttataagtc agatttttat
     1321 aatcaacact tagttttagg gagttttttg cttatctaca ccattttgat gcttaattta
     1381 tatacctaca tcacacttga agaacactta gtaattagcg atgcagggat cgagagaaac
     1441 atcaaaaggg tatccttcaa gatcacgtta aacaagccta ccgataaaaa gctctcagaa
     1501 gcgttctgag agcttttgac attttcttgt ataattttat cctaacacat tacaaagcac
     1561 ctaattcgag cttatatcaa gcaaatttgc tatttattac tcaatacata tctaaaaatt
     1621 acttgatgga aaattagata catggtaagc atgaaaagaa aatcaatttg agcagatgca
     1681 gtacaataca tagcaattta aaagctctca gaaggcttct gagagctttt aatatattct
     1741 ttgataattt gtctttctta aatccatacg tcctaaaaca agctgttttt gcttaatatg
     1801 atcatctgag agacatcaaa tcaacttttc tctcaacaaa tcattcaaag ctttcgacag
     1861 attaatattc tcttcagccg ctaaaacatt taaatagtgt tccacagtca ctgattttcg
     1921 atcataattt tgcttgtttc gagctttagc aactttcgta ttagctttta cgacaaataa
     1981 attaacattc tcagatcgct tgattcttgc atttaactct tgaacaggcg taggcgatgg
     2041 aatttctttt tcttgcaact ctaaaagcac caagtatcct tccaatactt cttgcgccat
     2101 ctcaaaagca tcttctaaag tttcaccatg tgtatataag tctggaaaat ctgggaattt
     2161 aactgcatat tcatttcctt tccattcgaa tactgcacaa aaaaagtatt tcatcgcatt
     2221 gcacctctct aattaaaaaa taatttttgc ttttttgttt caaaaaaaag aatcgcctac
     2281 caaaaaaatt gataggcgat cacaagctaa ttaacctcta aaggagatta ataccttgct
     2341 cccaaggcac tatatatctt agcatacgtc tgaagcatct tcaaacgagt aagatatatt
     2401 ttgcattaac ctaatttttt ttctctataa gttttttcat caaactcact agaaatatta
     2461 aactggacag caaaattgta atttctgcct tttctaactt tagcaaaatc aatattcagc
     2521 attgattttt cattaatttc ctcaactgat tcccttaaaa cacgtctatc aaaattcgat
     2581 attgttttat actcattttc tgttttcgta atctcacgaa ttttaactat ttcaatcagg
     2641 ggattcttat atatttcagc tttctcaaaa tctcctttat ttttggcgat aagatatttt
     2701 ttataataca tcgccaaata tttgtataac acgatgctat attttttttg aaaagatgct
     2761 aagtcttcaa aaacaaagaa cggatacttc tttttgattg agacaattaa gggaattaca
     2821 tcttctgaaa aactgaaaga tacactatgc tcttctaaat cccaatgaat ccgatcaata
     2881 gcagatacag tagtatacgt cttatatttt ttgtctagat tcgaaatttc ataaactgct
     2941 tgtctttgca aagtgttaac tatggttttt agttccgttt caagattttg atcaacatcc
     3001 atgtaattaa taatcgcttt aacaggtaaa tctactacgc ctgttttctt tagctttgtg
     3061 ggtgagatat aactgaacag caattgataa agttcatacg actttaaatc cattttcatg
     3121 tcaattgttg ctaagaactc ctcattgtac tttgtcagtt catctttttt caaaagtttt
     3181 tccttccttc acgcattttt tcagttgtta atcataaagg ttcacataag gcaaataact
     3241 cgtaattgat ttttcgagat atttaacagt attttttatt gtgtaatcct ccttatgagt
     3301 agcaacgtaa gataggtgat tgacaactga ttcaaatcct ctatctttgg ataaacgatc
     3361 ataaagcgga taaactttat tctgaagtcg gctcataagt ttaagatcgc ataagtcggc
     3421 agaactgatc aaaaagtttt tgattagtaa tttagtgtat ttgctattca tagctttcaa
     3481 gtacgattga ttcattttct ctgttttatc ttctgcgcct tttaaataag cagggtctct
     3541 ttgttcttgc ttataaggta ccggaactga catggtacgt gtaagcaaga actttatgtt
     3601 tgtataagta tgacccttct tgataagctc atagtcaatt ttaaaatcag tgtatttatt
     3661 cagttgggca atcggttctt taattacacg tctttcaaag tctcgaaaag ctttatattt
     3721 tttctcaata ctaaatttct ttcgtaaatc tgcaatggag aaaacaggat tttttaatct
     3781 atcaagtgat tttgtactcc atgttaagtt atctctattt gcttcataca gattaaaatc
     3841 tttagtgaat aattgaaaaa aactgatcgc atacttgctt gtcaagttaa ctacttgatc
     3901 aaatgtatat tgcgtaaaat gattttctaa gttcgttaat aaaggcataa ttgaactact
     3961 aaatttaata gatactgcat cagaaaaatc attgaattca gtaatttcta gcggtgagat
     4021 gactttgtat tcagtcttac cgttaggttt agttctttga attttaatga cagattgctg
     4081 atgcaatttt tcaataactt gttttaatct tgaatgtttt gaagaagatg aactagaaga
     4141 catcaacgca aataaagcct ttttagatac tttgacggta ttattaaaag gcggattttt
     4201 agggtcaaga tgtcctatag cgtaaagata aattttttgt ggcatagcat ccatttcaac
     4261 aatgctatct acaagttgat tcgataaagt aacagttaaa tcaaactttt ttagattgct
     4321 ttcggtagtt tcaaatttcg ggtttacatt cttttctgtt attttcatac gattgcctct
     4381 tctttctaag cttggtacga gcttaaaaac ttggaactgg tacgattcca ttgaataagt
     4441 atagacctgt tttcgatacg ttacaataag aaatgtatcg taaatttata acataactca
     4501 atgtcagtaa aacacatttt attttttcca atcaaatttc attgaaaata cagcagaaat
     4561 cgctatttta gaacattttc aaaataaaaa tccttttcaa taaaatacga aattataaaa
     4621 attaccaaaa ttaaaaaaca aatatttttc tagtttttag aaataaattc acatactttt
     4681 tctttttttg gatatattcg gaataccaca tcgctttttg tccacgtttg catcgctttt
     4741 tgtccacatt cacatcgctt tttgtccatg ttcgcatcgc tttatgtcca ccctaaaatc
     4801 tatttaagat tgatataaag cctttttgga ggttgctaaa gttttaaaga ttaaaatata
     4861 tattataaat ataaataaaa ggggaagctg aagcttcctc cttttccttt ttttcaatta
     4921 ttcaaagtta cacaagcaaa ataaactcct agatagtgtt agtttttttt aagatttttt
     4981 atttttaaga ttttgaaata agagaggagt aatcctcctt tattaaatat ctgttaatat
     5041 atctgttaaa tatctgttaa tatatctgtt aggggaggct taatctcttg ggagagtaag
     5101 tattaaaggg gtataaaggt aacacttttg gacagtaaag gtaacaaaag tggacagtaa
     5161 gggtaacagt tttggacagc aaaggtaaca aaagtggaca tttgaggtat cacactagga
     5221 taagacgtta ccttcggttt tcttgatttg gaaggcgaaa aaatagaaaa ttagattagt
     5281 aacaaatctt tgttgactgt tacctttagt tgtgatttaa tttaggtaac aagcagaaaa
     5341 aattgtttcc tttaattagt accagattaa catgattaaa ggagcgcaaa aagaagattg
     5401 gagagtaatc aatgtctcaa gaagttaccg aaaagattat tgatagtgat gtagatttag
     5461 tatcagaaca aacaaatgca attgtgcgtt ataacaatgg tctgaataca acagctttgc
     5521 gaggatttaa gcctgttgaa atggatgtgt tttgggctat tttatcaaaa atgaaacgtc
     5581 aaggaacagc agaagtaact tttgatttca acctctttcg ttatttggtc aaatacgaca
     5641 gaagagaaaa ggacagtttt tattctgtgt taaaagattt gagtgacaaa ctaggtaatt
     5701 taacctaccg ttttgaagat tcagacgtct atgaacagct gtggcttttt caaaaattcc
     5761 ggatagataa acagaaggaa acagttacaa ttaaggcaaa tgaggaattt gaatttatct
     5821 taaactcaat tggcaaaaac tttactcgtt ttgaacttga taattttaca aaactaagaa
     5881 gtagctacac aaaagaattg tatcgtcatc tcatgcaata cagaaataaa gagtggcgaa
     5941 atggttattg ggtagtcaaa gttgaagatt ttagaagagc attaagtata ccttcaagtt
     6001 atagaatgac aaatattgat aaaagaatac tagagcaggc gaaagaagaa tttttagctc
     6061 ctgatgaaaa cggaatacag gtatttgaaa cttttgatta tgaaaaaatc tatgcaaaga
     6121 aaggaagaag agttgatcgg ctcagattca cttttagtga gccagaatca aacttgccaa
     6181 ccatttcaat gcataattgg ttagaagaag attgagaaga agcaggttgt aattttaata
     6241 caacctgctt ctttaaaaaa gtatgggtaa cacttttgga caataaatgc aagaagtttt
     6301 tttgtaagca agtttcagtc taaataatat ttgaaagaat ggctaatcta tacaaatttt
     6361 aacaactatg ggtaacactt ttggacaagt caagaaaaaa aacaattttt cttaatttgt
     6421 tgatcgacta aaggtaacac ttttggacaa cacagaataa aaagtccggt gatatcagtt
     6481 ttggtaggaa acatcttaat atctttgtga gattgaaggt aacatttttg gacaagtcaa
     6541 ctatttgtta aaagttaata tagagtaatt agataagttt tttcttttcg tctgataaat
     6601 ggataatatt agttatttta ttgctaatta gtctttcatg atgactgaaa tagctaaaat
     6661 aaatatctcg ttggataatt gctgatactt taagggatat ctaaatttgc tgattgattt
     6721 atttatgtta ttatgatatt ataataacat aaatgtgtta cgcccgaacc tcattttaaa
     6781 aaaatgaagg ggtgagacaa tgaatgctat taattggcat gaatttgtta actatatgga
     6841 gagcttacta gatgatctaa aaagttttag tattgctgat gcagtaaagc atgggttacc
     6901 agttagtaca acgatgaaat tacgaggatt gaaaattcca gatgaaatta ttaagctgag
     6961 aactaaaaca attattgaaa ccgcaaaagt cgttgacaat atgaaccatg aactaaaagg
     7021 caagaaaaca acttacgaga aagattttga acgtttttta aaatctgtta ttggaaaata
     7081 tctaggtaaa aaatctttca gtgaattgag agatgaagag attgtaccta ctccaatggt
     7141 tagcaaaatc cgaaaaaaca aagccgaggg gaattactat cttggtacaa tagcaaaaat
     7201 cattgattat ttggaaaata aagagcaaaa gaaaggaacg aagaaaggaa gataattttt
     7261 gtgttaaata ttaatgggga agaatatacc gaaatgattc aaaatcccga acctagaatt
     7321 accgaaaaaa cgtctgattg tttgctcttt tatgaaaggg ggcagacaaa ctaatggaaa
     7381 aaaacgtcaa ttcaacatct accaaagatc aatacagtat tattggaggg ttgcttggtg
     7441 ataaggataa gagaacacgt cacggattac gcattatgct tgcaactttt ctaggagtgc
     7501 tttttttatt aacaggcttg ggtagctaca tttatcaatt aggaaactat aattattatc
     7561 tcgtgaacaa tacaacacct ataggctctt cattggagtt tgctcgatca ggagcagaga
     7621 tcactatttc agatgtgtgg acagatcaaa acagagatgt aacagtagta aaactcggtt
     7681 actcgcaaaa cgctagaaag ttgttatcta cgcaaggaaa aaactacaac ttatatatgg
     7741 caacgaaaga aaaagatcgt cctaaaaagc ttgaaatgag ctatgggatg ttaagtactg
     7801 atggggatgc tttcttattc ctaaaaggta aattagatga aagagcttat caagttttta
     7861 ttgcaaacca agtatcacta atttctggtg atgatacagc tgacgatgat accaaagtca
     7921 atgtgaatga agcagattca gttacaaaag cactttctca atattctatg aatgatgtta
     7981 ataatgaagg agtaatttct tttgggaaaa aagcaaaacc tgttaatact cctgataata
     8041 tcaatttcag aataaatcca tattcagatt caactaatgt ctatcaagga agctttctta
     8101 ccaaagatgg cgatattgat tattcaaaag ttgtagcagt tacaagtaag aataatgttg
     8161 taagtaagtt agaagatcag ttaaatgctt caaatactaa catcaagaaa attgaagcta
     8221 caaaagctga gtatctggaa cgtttacaac aaaatcctga cgataaagat tcgcaagaaa
     8281 gtattcgtca actagacagt cgaatggaga ccgaaattaa agcaatcaat gatacacaaa
     8341 aattgattga tcaatacaaa aatgctgact ttaacaaaga ttcttttgga gacatgaaga
     8401 cgacatttaa gtacctaact ctgactgact agaagtaaat tattcttatt ttagaggaag
     8461 tgaacacaaa cagatggaaa atagtaccga gttttttaag aatattcaaa ctgaatttaa
     8521 tcatgctctc acaccaatga aaccaccgaa acataagtta gtgggacgtg atgacgaact
     8581 ccatgagttg tcactgatct tgaatagacc ggaaacaccg caagctatct tgttaggtga
     8641 agccggaaca ggtaaaacag cacttgcaag tgaatgggct gaaagacagc gacaagatgg
     8701 aaagaaagta caagtataca aattatcaat cggacaattg cgtgttgggg gagatgatgt
     8761 cctccaaaca cgtttagaaa cattaattcc aagattgaaa gaatatgagc gaattttaaa
     8821 atctgaggac aaagaaaatg aatttgtcct cttcattgac gagtttcata aagttgttag
     8881 ctcttttggt agtggcaata aaattggggg tgattcgcta aaagaaccgt tagcaaatga
     8941 atcacttcaa ttgattaccg ctactacaag aaaagaatat gaaaactata tcaaaagaga
     9001 tgatgcctta gggagacggt tacaaccgtt agaattgaat gaactaaaaa gcgatgttgt
     9061 cgtcgatatt ttgagacaat ggctaaatac atcctctgtt aaagatgatc ctcaggcttc
     9121 ttttaaatta tcgcaaagga ttcctgatga attacttcaa gaaatcgtac aagcaaacaa
     9181 gctttatcgt gaggatttgt ccgaaccggc taaatcaatt gccgtaatgg aggatttgat
     9241 tgcaaaagat cgagtagacg gaaatgctta taatcgagaa agtctattgc aaatatttgg
     9301 taagtataat attcagctag attctgattt tgatatggaa aaacttcaag aggaattaaa
     9361 gtccataaaa gggcaaccgt tagcagttta tactataaca atgttgttta aacgtatgaa
     9421 gcttggattt gatcgtttta aaggtcgaaa gcaaccaaaa gcaactgctc tgtttacagg
     9481 atcaacaggg gtcggtaaaa ctgcaatggc taaagccgtg gcaagaggac tttatggcga
     9541 tgaaaataaa gttctcttag ttaatatgcc ggactacaaa acaaaagatg atgcaatgcg
     9601 ttttagacga ctcataggta ctcatgtaag gcatgatcct tctgcgatta ttgtgtgtga
     9661 tgaatatgag aaagctggtg tagaaacact cgatgccttt ttatcaattt tagatgaagg
     9721 taggataagt tttactgaaa gaggatggga tgatcgagaa gttcacgaca ctgtttcatt
     9781 gtcaaataca attttatttg cgacaacaaa tgcaggtgcg gagatgttcg attcgttaaa
     9841 cagatatagc tcactatctc gtgttacaaa caaggaaaat tctaatgaat atagcactga
     9901 actaaaaaga gaataccgaa aagtcgcatc agggatcaaa caagccttga ttggtgaagg
     9961 tctaaagcct gaagttatta accgatttgg acgaatagtt ccattttggg ctttatccga
    10021 acaaactctt ctggaaattg cttataatga aatgttgaag agtgctgaat tagtacgaaa
    10081 acatttaaat atagatttac gtcttccacc taggaaagaa agagtatatg gtcaaaattt
    10141 ttatgcagac gatctctcca tgcacttagt ttttgacatg gcttcacaag aggattctaa
    10201 atcagggggt gcaaggaata tcttgcattt agttgaatct gagtttgaag aagcgattac
    10261 tgaagcaata attacttatc caaacgcaaa aatattcgat gttaagttga gtgaagccgg
    10321 agcgtttgaa ggaaaaggtg attctaatgc tgaaattatt gcaaagcctt ccgttgctga
    10381 aagtaaagaa aacaagattg tattttcgat tggaggggcg tagctatgaa attcaagaaa
    10441 tatttactac aaaaccttag aataaaacga tgggtcgtaa gaggtctagt tattggagga
    10501 gtattagcag ttactttagg cgctcctttt ggaatgaatg atccaactcc tgacaatcaa
    10561 gatagcaaac aagaaacagt tataaataag aacgttgcat atgcggaaag taaaccggca
    10621 gaacaaggaa tgtggacact atatgctcgt atcctaatgg gagataaaga agttaatgat
    10681 agtgccgcta aaactggaca aatgaatttg ttaggacaag gtggtatcag tgccgatttc
    10741 ccttattctg acatttctaa acaaggtaat tcgattgcag ggggtaatgc aggtactcaa
    10801 ctagcatcta ctttagcaac ttatagttac tacggatata ttgaaacagt ctcaggaaat
    10861 gctattgcca gtcaagcatc atccattcta ggaagtattg gtaggacgat tggtagtttt
    10921 atcggatcaa ttagtttaat cctttctaat attgctgaat ccataaatga actccttgga
    10981 aaatttttca tgagtatgaa tatattttct cttatggggt ggggagaagg tggatcggat
    11041 gtatctaatc cggtatctaa agcattaact agcttgctta acaatttggg attaaataat
    11101 gaattattta aagcgatagc aagcttatct atgctctttt tcacagcaat actaggttat
    11161 caaggaatga aattattgtc gaaagatggt gttaactcga agggattatc accagtactt
    11221 gaaaaatgga ttgttcgtat ttttgtattg tttatattct taccagtggc aggatcgcta
    11281 ttgggagttt atatcaacgg catccagtca gcaaaaaaag atggagatat accaacaaat
    11341 gttgtttctg actacatcat taacacaaga ctttgggctt ctactcaaaa tcttgctcca
    11401 tcatctgata ctggtggtga tgtacctgac ggaaagccta catccgaaat caagttcgtt
    11461 gatacagatt atgaaccatc taaaaaatct gcaatgataa gagcgatcaa tactagcagt
    11521 tatgccagac aaaataatga tctagattct aattcagtcg gtatggctct attaaaagaa
    11581 tggtcatcga atgatacttt caatattaat acttatgccg gtgatgttaa tgtcgccgaa
    11641 aatgatgctt atatgggaag agcgcctgct gtttggacag gctataattt aggggatgga
    11701 aaagaaggaa gtgcaattaa gaaaccaacc aatttaaatg gatatatttg gtcagcaaat
    11761 caaaatgtga cagacgacaa tcgcaagcct gatggaaaag gaacagcgca taactttgat
    11821 gctactcaac cttggggcgt tgctaacaat gcaactttta gcacacagtc ggtagcttta
    11881 ttgctccaat cggcacttga tacatcggga gctaagtttt atgcgtataa tatcgctcct
    11941 tcaggaattc aaggcagtgc taagaatatg tcaacagtaa aaacagaatg gcgtacagca
    12001 tccttagttg gtcatggagc tatgggtaag tttggctcgt ggctagcgat gaacgctgaa
    12061 tcaatcgttt tagcagttct ttacttagca tgtgcttggg cgatgttcaa tgtgaatatc
    12121 gtgaaagcat ttaaacgtga atttattcgg atttgggaag tagttctaac aggatcactt
    12181 gcatcaggag caggtgtgat ggcaatttca ttaggtgttg ttacaacatc tctgatcgga
    12241 ctacaattac ctatctttct gattactttt attcgtgcat ttggtgatac tgctgtggga
    12301 ttcattccta atacattagt tggcgatggc gtagcaaata ttgttcgatc tgctatgatt
    12361 ttaggtgtag gatatctttt agtctttaaa aaaggcgaaa aagtaaataa tttgattaat
    12421 atgcttattg gcttaccact tgaagtagcg tttgggtttg atgaacgtgc taagttatta
    12481 tttggtaata gaaatgatgc tgtgcgagtt gtggacggcg tttctaaagc aatcaagaaa
    12541 agccaaggag ctaaaaatcc ctattatgat ggtggcaaca gctcagtaaa agatatggtt
    12601 gcaggaggtc ttggagcagt tggagcgcaa aaaatggctg aacgtttgaa caatatggga
    12661 gatagcaatg ctgatgctaa gtccattgct gataaagtaa ttcctgaaac accagaagga
    12721 atgtcattca acggtggcgg agttggttcc acaatcaata atacctcttt caaagattta
    12781 gttcgtcaag atcaactacg taataactcc caacaatata ttgatcattt aggacgtatg
    12841 gttgatgaaa acggaaactt tgtcgatgaa aatggtgaaa tattaaaaga tagtaaatac
    12901 ggtaaagatg ctaaaggcaa ctttattgac gaaaaagggc gtttggtcga tgaagatgga
    12961 aaccttatag atactaatgg taaaccattg gaagatagtg aagatggtaa tattggtatg
    13021 gatagcgaag gacgtttaat tgatgaaaaa ggtcgcttag tcgatgaaga tggaaatctt
    13081 gttgacgaaa atggacgcag gttgctaaat ggtgattttg gtcatgatag taacggacgt
    13141 ttagttgacg aaaaaggtcg tttagttgat gaagatggaa atcttgttga tgagtttggt
    13201 aataaacttg gtaaacacag cgatggatat aatgtgaatg gagatttagt cgatgaggat
    13261 gggaatatca ttgagacgag agatgcgctt gtggcagatc gaaatagaga actcgaacaa
    13321 caacggcata cgccaattgc tgttgcaatt cctgagaatg aagaagacga gattacttta
    13381 gatcaaactc atcaagaact gaggaatgaa atgagtggtg aggacgtgtc agacagagtg
    13441 catcgggaat taggagatgg agcatctggt gaaagtcagt caagagagct taacagcaac
    13501 tttgataata gtgctattcg gaatgacaca gtacttaaag acagagaatc gctaacaaaa
    13561 gaaacggata aagaacaatc agatgtgaag aaaaagttca ttcctactcc taatgttaat
    13621 caaacagata aatatgaaac aaatattgga tcaggaatgt cgaaagacaa tcaatcaatt
    13681 agagaacctg aactgacaaa taaaaataat agaacaaata attctaaatc tacttcagat
    13741 aattcaggga aatctaatca atcaaccaag aaaacatcaa cagctaaatc agccgttgaa
    13801 tatctatcaa aaactggtaa aaatgtttac acctcagcag ataaagcttt agcaaaagct
    13861 ccaaaaggta gtctagcagg gataacctat gaagctaaaa acgaagctat taaaataggt
    13921 aaaggaacgg ctaaggttgc caaggctact gctacaggag catccaaaac tggtaaagta
    13981 gtgaagaaat ctaccatgtc agtcaaggac tatattgtaa aatacggtaa tcaaaaatca
    14041 actgaaaata agtctgaaga cgagtaaaaa gaaggagcat tgatttgctc cttcttttta
    14101 ctttgatttc taactgaaga tgtcaaggaa aatttctatt tatgcaaaaa aattatttta
    14161 aattgtctat aaatgaatta aatatttact gttcaaagtt gtataattaa aaagggctta
    14221 tgctggtaaa gaacagaatt attatctaaa caaaaacttg ataaaccagc atttttagcc
    14281 aataaaaaaa gtgaaataat ttaatggaaa atctctttta atcatcgaaa atttatgtta
    14341 ttatgataac ataaagatgt aaatatcgag acgtcttttt cttagttaga tcattgacaa
    14401 gtgaacaaat aagatttgtc gatgatataa ttaacttatt aaaaatatta aaaaggaggt
    14461 ttttatatgt tcgattctat taaaaatttg gttagcggaa tgacgcctga tatgaaaact
    14521 ttagtacaag ttgttttgta tttcttggca ttcgtttttt cgttgaaacc aggattcact
    14581 gcaatgaaat tttttggtga tgcaaaatgg ggagatggat taaaatatgt tggggcgatt
    14641 attgcaatct ttattattcc tgtaattaca accgttatgc tttacacaat gggtactaaa
    14701 acaggtaatg atttgaacca aaaagctaat atcatatcag cacttattcc agttgttggt
    14761 atctatctag tttcaaaatt tccaaaaaat gaactgttag gttaaaagtg aattgaacaa
    14821 atttggataa tatgccgatt tgttcaattt actttttacc aaaaaactac gctccaagcg
    14881 tagtttagaa gtgagggaag aaagtaaatg taagatggtt tttgatagag aaaaaatgtt
    14941 agctcacgcc aacgaagtat taatgagcag tctgaaaggt accgaactgg caaagataat
    15001 gaatatgaat gttaaccagt tctatgatta tcgaaatggg agtaaaaaga ttgaaaaagc
    15061 cagacttgaa acgcttatta aattcgaaaa agcatatgta tatatgctag ataaacagaa
    15121 aagaactatt gactgaaaaa aggagtttta caataatggc aaaattcaaa gatattaccg
    15181 aatctattaa ttatgtggca gaaacagttc ctgtagttgc actctctttg aagccacaat
    15241 tactcgaagt gtacaaaaaa gaagaaaaag aagcgaaggc aaaaaaagct aaagcaaagg
    15301 tatggaaaga attcgatgcg ttgctgacca aagatttacc aaagaaaaat tatatggtaa
    15361 ttgaagatgt acaaaagctc aacagtgagg gagttataga tgaggatgat gctattctcg
    15421 attctgagaa gtatgtcgtt ctattgaagt caagtttgaa ttatgtagct gatctaccag
    15481 aaaaatttaa agagaagcta ttagcaggtg tccgttttat ggatagtagt ggtcaattat
    15541 tagttattcc ggatgatcct aatgtgtttg aatcagaagt tgaagaagct acagacttct
    15601 atagcgcagt agagcaatta gaagtagcta ctaatggatt agaacgaatt gctgagacct
    15661 tcaactcttc tgaagaagtt gaatttgaag ccgtagcaga aaatgtacca gatgaaaaag
    15721 aagctctttt tgtggatgat aacaaaccaa ccgaagcaga aaaccaagaa gtaagcatag
    15781 aagaaacaca aatacaaaca gaaacctacc aacaaccaaa aattgatgaa aaacccgaat
    15841 cccaaagtga caaagaaaat tatgtttatg aagctgaaaa aatcacatct gaaagtgatg
    15901 taccgaaaaa cttagatgct gattttttag aaaaaaattt tgaacagatc attgctgaca
    15961 aatttcaacc tgtagtttta gatgagatta atgaccctgt cgatttaaac gaggagatgc
    16021 tatccatacc tgagttgaaa ccattgctgt ttttagctaa agagagtatg aacgctcgca
    16081 tctctattgc taataataaa atcaacagtg aattaaataa gacgaaggag caattgatcc
    16141 tcaaaggaaa gcaaatgtta gctgatgagc ttttgcggat agaggaagca acctcattaa
    16201 atggtcaaaa tcagtttaca aatacactat cggttgctaa agagagctac gaagcagaag
    16261 catctaaaat tgatgattta gtgatggaaa aatccaatat cattcgtaaa gattatgata
    16321 tggcgaaaca ggcttatttg gatgctgaac taaagaaact agagcaacgg tatgatgctg
    16381 agcatttacc agaagttaaa caacaagaag atgaatatag aaaagcaact gaagaaagtc
    16441 ttgatcaaca gtaccaagaa gcaattgaat ctattaaaaa cgatgcattg aaacaaagcc
    16501 aagaagcaaa agaagttgtg gtggaacgaa ttatcaattc attgaaacca gaaattgaaa
    16561 aatcattaac agacgtgcaa gaaaaaactt tagagattgt cgaaaaaaca aagtcagaaa
    16621 atgaagctga gttccatgat acaaaagaga aaacaacaga tgtggttgtc aaatattttg
    16681 cgaacaaaga agaagttgaa aagcaggtag ctaacaacac gaaagaatta gaaacaaaac
    16741 ttgtagagca acaaaaaact atcgaagaat ataaagatcg aatgaaagag gtcaaagatt
    16801 tagcagaggg ttataaatta aatagcgaaa agttggcaga acaaagtgaa gctttaagag
    16861 aagacttatc tcgttcccga agtgatctag ctcaaatggc agaaaaaacg aaatcattag
    16921 cagttgctac agaaaatcaa tcaagttcaa aacgtgattt tacaagtaaa aagatggcta
    16981 ctatcatttc tgtcgctgca atggcttgcg gaacgatctt gggatcgtcc tactttatta
    17041 gtcataataa tcaacaagca caggctcaaa ctcaaacatc tatttcgaga gtggaaaatt
    17101 cgattgggac aaatacgaac tctgcttcaa caaatagtag ctatgaagca acaccaacta
    17161 cagagttcaa agttgggaaa gatgttgtca tcagtattga tgggaaaaca actaaggctg
    17221 aagtgatttc tattgatgga gaaaaagcag ttgtgaaaac tccagacgga aatcagtaca
    17281 aaattcaagc tcacttatct gataataact aaggagggct attatgcgag aagaaaaaat
    17341 agtttatcca gtaattcaaa acaatcaaga aaacatgacc tcttctcagc acttacagga
    17401 agcacagctc gtgtatcagg taaatgaact accacaaacg aacgagacaa tgagcaagtc
    17461 aatatcttta attggcttgc ttattgttgc aatagtgata actgtaggtg tttaccgtaa
    17521 gttgaacgtg aaaggaagta tttctgatgg cagataactc aaactatgga tttaaacata
    17581 acttacatca aaaaccttct gaaacaattg tcagagttga atggcttgaa aagcatgtca
    17641 atagcaccta ttctgttaca gcaaaaagat taattgtatc agctatagtt gttgcagtcg
    17701 ttgttcttgg atcaattgtt tacttagttt ctgatacgat taaactgaaa tttatttttg
    17761 ttccaacgtt attaatgata attggatttc ttattctaat tagccagtat atgtttattg
    17821 atccatctag tggttcattg atttctggtt ctattagact gttcaaatca gtagttaatt
    17881 cagcaagagt atctatgggg aaaaagaaac catttcgagg cacagagatt ttaaaagtga
    17941 aacaagatgg aacaatcgta tatcgagatg ggagtgtagc attaatgttc aatctagatg
    18001 gggctacatc actaaccgct tttccagaag aagttatggc tcaggaatcg aaatcaatac
    18061 aatatcaaaa taccagagat cgttccttag ctgaaatcaa aatcacttca tctcaacctc
    18121 agaatacgga aagacaaact cgaaatatga aaatacaaaa acgaaatgca aggagtaaca
    18181 aagcagtctt tgacataata gatcagcaag aacgatttgt atcagaatat attgatggtg
    18241 tgaaaacaac agtaatccaa tatcttatct tgaaatctca atctaagatg gtattggatg
    18301 aaggtgtgga acgtttagaa aactatacga gtagaggact ttattatagt gtcactcagt
    18361 tgtcagctaa acaaacaaaa gaaatattat ctgatattta tgcactgaaa tagaggtgag
    18421 agattaaatg gaaattatgg gtagatcaca actattaaat ttcaaaaaaa agagaaaaac
    18481 taaaaaagaa caaaaaacta gaaattcaaa ggtagtgaat aatacctttg ttagtgattt
    18541 aacatcttta gttggttatc aatttacacc atcttacatt aggacaggta agcggtgggg
    18601 aacaattgtg aaattagtga atacttatgg aatgaataga aattatggat ttggttggat
    18661 ggttaaagct attcctgaag tgagagtaga aggggtaaaa gcctatctaa ttgaagcaga
    18721 taagccagtg tcacaaaaag atcaacaaga aataatgcac gagaatgttg ggggatcaac
    18781 gaatagttat gaaaataatt tagaaggaaa aaattcagat gctgaaatta gcaaaactgt
    18841 tatgcggatt atggatttga atacagcatc tttactagac agcatggcaa ataaaattat
    18901 tgattggaag ctagaaatcc tattagtatc cgattctcct aataaaatca gcgaacagct
    18961 aattaaactc caacggttgt atgatgaaaa aatgtatgga ttaaagctta tgtcatatgg
    19021 aggagatcaa cgtgatctgt ttgatagact tttaagtgaa ccaatcggga atgtctatga
    19081 gtatacgtct atgagttcgg attttgcagg aaatgatcat gcaattcgca aaggtttaga
    19141 tgatgcgaat ggatgggcta tcggcactat gtctactagc tacgcaagtg gtgtagcttt
    19201 tatggcactg gatgattctt ttacaagtaa agttttagtg gcatcacaca aaaacgctac
    19261 aattaaaggc tatgatgaaa aaatctcagc atcatcactt tgggggcaat tgattgctaa
    19321 taatgcaatg gcaaatcata aacgaacttt tcatattgtc ttaaataaat ttgattactt
    19381 tggtgatcca actggtagaa catttgttgc caaaccttcg ttaaacagtg taatagaaaa
    19441 ggttaatttg gctgaagaag gtcttaactc tttggagctt tttggtaatc aaaaggacat
    19501 tggtgattta tatagacgga atctcgataa actaactcag attttttatt tgttagcagg
    19561 cagaacatta gattctgcaa ctagagtttt attgaaaaaa gaattaggta acttttatat
    19621 aagtcagaaa ctttgggata ttaattatga agaacgttca aaacttttgg tgaacagtag
    19681 tgatacaatg ccagttcttg gggattttat tagctatttg actaatgctg aaacaaaagc
    19741 caaaaaatct ggtactgaaa aagaagtcga tcgtattatt gtattaaaag acacattgag
    19801 aacagcatta gacagcttct ctaggatgtt taatcaaaga acgacactga aagaaatcgg
    19861 taaaagtgac aaattacagt tttactataa cttaggtgat ctaagagcag aaaccaatgt
    19921 tatggaagct caatttttaa atacctttga tttcatcaca tcacaagcaa aaaaagatga
    19981 tattgttatg attcacggct tcgataagtt atctattgaa accgttgggc taattaaaaa
    20041 aagattaaca atgcttgaag aagatggaat tcgtcttgcc tttctatttg atacaatcgg
    20101 ttcaggagaa gacaatgaat acaaagaaga tattgaaaca gctgatatat tcaatacaga
    20161 tggaaaaatt taccaaagtt ttgaaagtga ttttaattac actatcattg gaaagatgac
    20221 cagtggagag ttaatgaagt atgaaaaaaa agttgctcct gctagaaaag gagaagatga
    20281 tcaaaaactt tctgttgatt tgagacagta tttgacaaca ggaagaagta ataaatttca
    20341 gatcaggaga ccagtggatc tgactaataa ttttgttatt ggagagttta ttctttaagt
    20401 tttatctttg attttgagtg tataaggaaa ggataagaaa aaacatgtat atttgagact
    20461 aaaaacagtc ttagagaaca tggtacgttt tgtgaaaaga gaactataga aatttcataa
    20521 agtgaaacct tattgagtga aataattata gtggaggtta aataatgaaa ccaaacataa
    20581 aaattttaga tcgaatattt ctaggtagag acacagaagt aatcctaatt caacatgaag
    20641 aaggatttga agttagtata ggtattcaga aacttcaaaa acctcattat tgtaatcagt
    20701 tgtataaaaa ctttactgat gaagaaaaag cgagagtttt ttttaatgaa gtcaaaggta
    20761 tgagagaaca gtatgaggtg gttgaagcat gaataagtta ccagaaaaga accgtgtatt
    20821 tagattgaaa ggtgatctca gtcaatttaa aatagatgag aatggacaat tttttgtttg
    20881 gatgcgacat gagcattgtt ggtgtaatcc ttttgtgtta aaaaaagaaa atgaaatcag
    20941 aactaaaatt gcaaatggtg agtgggatta cctcttcaga tgggaagatg aatcttttat
    21001 agcaaatgat atggatcatg catttgtctc atttctggat aatacatggg gtacttggta
    21061 cgattgttac ctagaaaaat tgggctttca aaatattgat attgatgcta ttgaatgtct
    21121 taaagaagtc gatcaaaagt atgaagaaga accctattat ctcttgcaac aaaaattagc
    21181 caataattca gtgtttcagg tagaaatttg ggaaaatgaa gatggaactt atgaggggct
    21241 agcgcaagaa atacccttct cagataggaa gagttcgatt tgaaaagagt atatcagcaa
    21301 tttttatgaa gtgaaagcaa gcttacaata tagtaatgga aaattgtggt tagctggaag
    21361 gtatattcca gctaaccaaa tcttacgttt tctgggagag tggcgtttta aaacaatttc
    21421 ctaggaaaaa tagttaacat aaaaggaatg aattgttatg aaacaatatt taaatgaatg
    21481 gaaagcgata gaggggtcat tagtaacgca aagaataaag gaattacctg attgcttaga
    21541 gaaggatcat ttgtttcaaa tacgagaaat gttgaaaaaa gaacagtttg atccagacca
    21601 atttttagta gtcgagtatc caactattgg agtgtactgt tgtaaccata tcaatgatgg
    21661 aaaatatttt attattcagg agtatggagg acagttaact cctttctata ctacatggga
    21721 aatgagtgaa gaaggaatca ataattttcc atgtgaaagc atcgaagatt caatttcaca
    21781 caccgaatgt taattgatta taactataaa aaaggattga acattatgtt caatcctttt
    21841 ttcaatgaaa tgttttccgc catttcattg tttggtgcga tttctatttt attatatcaa
    21901 aataaagaga gattctaaag aaagaagagg gaaatatata aatcaagcga cagtatattt
    21961 attattaaat gctattgtga gaatataact aattagttta atttgaaagt aaatatacgc
    22021 tataaaagtg catcttgtgt tataaaaaat tattttattt tgtgaacata atttaacaat
    22081 tctttctcgg aattgatttc ttttcttaaa tagtcttcag acttattaat aatattatct
    22141 attatgtcta gatacatatc acttttcgat tcagctaatt catacagttt ttttaattct
    22201 ttatccttta attgaaaacc ctgatccata gtcactgcat ttggatatag aagcccacta
    22261 taatgtttac gtaaattcac ttggaatttc tgattataaa agtctaacag attagaaata
    22321 aaaggcggaa aattactgtt tttgtaaaat tgattatttc catttaggtt gtatagtaat
    22381 ttgttaaatt gctcctgatt taatttattg taaatccatg gtaatacttc catatcctta
    22441 tctgctaacc tgaatgaact agcatcggta agatgttcga tcataaaatc tatgaacatc
    22501 tctttttcac caaaatataa atattgatta tatattgttt ctaatgttga agatggtagc
    22561 gaagaaactc tcattttttg ctggagtata ggatcaacta gactatttaa gtgattttgt
    22621 aattcttcat tgttgtttcc tagaactgca agggaacgta aacggtagta atattctatt
    22681 tctgttagta cttgttgttt cggtttaaaa tcatttattg atatttgtaa attttgaatt
    22741 gtctcgtctg aaaaatcatg ttgtaattct ggatgggtag ctataaaagt aagtaaaaag
    22801 aacccttttg tatacgtgat ctgttgattt tcaccaagtg atttattaat ttcctctctt
    22861 gattcagctg tgaacctata ctttgcaatt tcttttttta gaatatttaa atagaattct
    22921 ttattatcaa aaattagggc attaagtagt ctgaaagtac tttccctatt tctatctgct
    22981 tcctcatttc cataagataa ttgaaaaaca aacttaaagg ctgtcttaca taggttttct
    23041 ttggcttttt cgcttagttt atttagatag ctatttttta gtgcagagtg aaattcttca
    23101 ggtgtaacag acatagcatg tatgcgactt gcatattgta taatttcgat cgttactttt
    23161 tttcctaata ttggattttt taggaatata atttcatagg acttccgtat aacatcctga
    23221 caagtttctt ttgttatatc tcttaattcc caagtattac cgttgtaagt gactacagga
    23281 tgagctgaat aatttctttg atccttaata tattttaaat cctcatattc atagctatca
    23341 attagctcag ttgaactata agctttttct agtagttcca tttcccattt tggagagttt
    23401 ggatcacttt ttcttagtct agctatatct tctaaaattt tcttagaagt attatcctcg
    23461 taaatatttg ctaaatcaga taatttatca attaaatcta aaataagcgc actgtaattg
    23521 acagctattg cagaacgata atttccctga taaaaactac ttctaacttc ttctaataat
    23581 ggaataattc taggattttt aacttttttt atttcatcat ctaatataaa catataaatc
    23641 tccttttttt atttgtatga caagtttacc ataaaaaaaa attaaaaagc gagacatatt
    23701 tatgttgttg tgttatcata ataacataaa tatgtagagt gagatgatga aaaaatggat
    23761 ttgaaacaat cgttttacat ctggttatat cctgataatc ctatgtcaat aatggctgat
    23821 atttttgtag ttagcatctt attgtattta ttttatctaa ttttctttca caatttaatc
    23881 gggtacatga ttcttgattg gaaaggaatg ttcgatatag aaagaaaacc atttgctaac
    23941 aatcaaacct ataccgtctt cgaaagtgga gattgggaag aaaatgaagt tgatgtgatc
    24001 catgaaattg gattagcttt atcaggaata caagatgctg atgttttggt atcaatgaca
    24061 acggatactg gatacaacgc ttatgaggta ttttatctta tgtattttat atggcgtgat
    24121 ggtcaagaaa ttatcaatgg tcgtgctgaa aaaacaatca attctaatac tgaaatttct
    24181 ttttgtatgg gtgaagggga aatgattgta tataaagatg ggtcagcaaa cattaaaaca
    24241 gcctttggtg atattgaaac aagtattaag gaacttaggg aatatgtgca gaacccatat
    24301 aattttcaat atttagcagg aagaataaat ttagtttagg agtaaaaata tgaaaaaaat
    24361 tataaatcaa ccaacaaatc acttgataat tgaaggtgtt attttcgtaa caatgtattt
    24421 tactgtagga aatggcatct caaatacaat cattcaaaaa aatccacaat acctattatt
    24481 tagtctttat gcttggattg tacaaatggt ttgggtttcc atattgatgc tgttgtttta
    24541 ttggatagta cgggttattc ttttattgtt aaacaaaaga aaaaaggata ggtgaataaa
    24601 atgaaatcaa ctaaattgaa ggttgtattg ttatcgacag cagcattaat aactcttaca
    24661 gcatgtggta caactaatag tgctgataat aacaaagaca caaagtctag tagtacggtg
    24721 gttactaaaa acagctctac atcggcatca acaacaattt cttcaatgac tgaaaataat
    24781 gctgaaaagt atcaaaaata cgaagacatt aataaaggtc aaaagccgga agaagtttat
    24841 accgacttta ttaatacagt aaaaaatgat gaagattatg ggaatgatcc attgcaaaat
    24901 aaaaatctga ctatcgttct ttacaaacct gattgtccag attgtcaaaa agcagaatca
    24961 aaaatcatgc aagaaataaa agaaggattt agttatgctc caacattaat gcatgatatt
    25021 accataaata aaccagctta cgagtatcac gcagttgctg tagatattac tgatggtgta
    25081 cctgagtgga tacaaaacat tcctggtctg gctgatgaga acaatcaata tcatacgcca
    25141 acagttgcag tagtaacacc aaagaaagtt aatggcacac tatactggga tgtaatggga
    25201 atgacaacaa atacaactga tgaaatgatt gaaagtacaa ctaaatatta tatggatttg
    25261 ggagcatata aattatatca acagtcagaa cctgttatgg acgatcaatc caaagttaaa
    25321 tagttcttta gggcgtaagc cctatttttt taaaattaag tgataacaaa taaatgattt
    25381 ctgaaacaaa cgttcttact caactactcg aaacacacaa gctaattaac tagattataa
    25441 aggagaatgc gtaatgaaag aaatcagtgc aaatgaagct catattccgc aaaagaatca
    25501 ggttggtata tataaggtgc ttcatggtga aggaatttat aaaatacagt tacttaccgg
    25561 ttacaataac ggtgcaaatg ggaagtggtt aaaggcaaaa agtattcgtg aacttaaaac
    25621 tgaagtagaa aaaataagac ttgggttaac aagggaagaa ataagtagac tgagtgaaaa
    25681 ttcttctttt gtaatccaaa aagaaaagga gaaacatcta cttcatcggg aactaataat
    25741 tgaaaaatac tacgatgttg atttacctga tcagttaaga attattgacg aattttcaga
    25801 gaaaaagtgg aaatctgaaa tatacccaag cttaattcaa tacaaggcat caggaaagcc
    25861 catgtataac tacacaggct ttttaaacta cacacaatat aaatatgcct ttcgcaaatt
    25921 aaaaggcatt aaacaagctg acattgccct gtatgagatg aaaaaaatgg atagattgaa
    25981 attgattcaa gagttagtgc aaaatacatg gaatcaagcg attgtcgaac tagaaaaaga
    26041 aaatgggaaa attttaacta atgaatatct gatcgtaaat gaaattgaag aattaattgg
    26101 tttattttca tgtgaaaatg gtgaagtctt cttgaagtca tcaccaatct attcaatttt
    26161 ggacagtccg tatcagttta tacaggtaag gagatgagtt acatgtctag cttgaaagat
    26221 gactatatcc aagcaaaaca agagtatgaa aaaatacaga tgttaaaatc tgagaaagtc
    26281 gaattatttt taacacaaaa attagcagag gatcatattg ctaacttaga tgctaaaact
    26341 ttagaggaat atgatcagca gtttaatcag acacatcaca atatcatttt gcttgttgat
    26401 caggcaaaga gaagacttga aaaagcggaa tatgaactat tagatcaagg aattatatgc
    26461 ttggataaag ggattcgaag atattatagt gcagagttaa aaaagcaaaa tgtagacaga
    26521 catgcgttaa aacatgaaat cttagaattg ataatgcaac gaatttgaag ggatagaaag
    26581 taaatgtcac aaaacattag tgctgtaaaa caattaatag aaaaagattt agagacgaca
    26641 gttcagaggt tagccgaacg aatccatttt gcaaattatc aaaccatctc taattggtca
    26701 agcaggaaca gaaatccgga agaaattcca atgaaatttt tttatcgaat cggaaaagaa
    26761 tatggtgttg atccgataaa aattttcgaa aagaccatga tttattacta tcatggaaca
    26821 cctaacgaag tgttggaaca tcttttggaa gaagcagaag aaaaatcatc aatattagag
    26881 atatcacaaa atgacaaagc tattcaagtg aaatgtgttg atccaacagg aaagattatt
    26941 gttggatttg atattgaaag aaaatctaaa atagatttta ttactcaatt aacaaagata
    27001 aataatttaa atattttaac acttagacca gatcatgaac agttgtttat gagttttaaa
    27061 aaacaattga aagaaataca aaaaagatat aacaaggtgt tttctaatgc gtgaaaagct
    27121 aaaagaaatc agagtgtttt ggataattaa caaagaattt attatcttgt atacacttgg
    27181 atttatcagc atgatcttgt tttggtggtt atatttaaaa aagtaattta aaagtgtcaa
    27241 ggagattttt atccagagaa ggatgtggaa tttgcatgtg gaataataaa ttaaaaacag
    27301 gcttgttatt aatagttatt tcctgcgcta tgatggttgg catgataata caaagggaac
    27361 aatcttattt tgaagtttct gctaacaatg taatagaaag atgccattat ggtcaacatt
    27421 tttggactgg ggaagtcaga gaaaatatag atcgtgagta tgttcaaaga atcgtttggg
    27481 atgcatattc tatcaaagat tatcctaaaa gtttaacgag tagattattt tacagcgaaa
    27541 aagataatca aaaactctcg aatttgatga tgaaaaaagt aaggaaactt gcacaaaact
    27601 atttggaaga aaaagaaggt aatagtccaa ttgacaaaaa ttgatgacac tgcaaaaaaa
    27661 tatagagttc gaattagctt ttttcggagc attgtttttt aggtgaacta tatttcatca
    27721 ctaaaatcag agataactaa cttgaaacat ggtcagatgt gttacttgaa gtctctgaat
    27781 aatcaatgtt atctagtaga attaagcaac taaaaaagaa agaagtaaga aaatatggca
    27841 tacgaaaatt tacaattagt agtcgcagaa gttagtgggg atatatacct tacaaaagta
    27901 aaagatggaa ttatggacac gaattatagg agagttgcta cagatgatgt gctaagctca
    27961 tcgacagaat ggtttcgaaa aaatgaagaa tctgctgttc actttgaagg aattgatgga
    28021 aacattcata gtttgttcta tacaaaagac aaagaaaaag caaaaaaaat tcttgatatt
    28081 ttgaaaggaa ggtagttaat taaccaatga tataagagaa tgtgagacca agtaaatact
    28141 tggtctctat aattttagcc actagtcaat taaatagcta aacaatttta ataataataa
    28201 aatatgactg cttcataatt aagaagtgca gaatttttct aagaacgata tttccttgtt
    28261 gaaatgagta ttgctaacaa tttgatcacg aacagcatcg ttacaaatgt tgtatcaata
    28321 tttgatagat tacatattct attaaaaaag aaaagaaaat tattgatatt atacacatta
    28381 gtgtgtataa taaaagagag ggagtgatta gaactttgag caattcacta attgtttaat
    28441 aatagaacga ttcctaagaa gttcattgtt cattggcaaa ttgctttatc agattgaaag
    28501 ttggcgaata aggtttgtag aataacacct tttcaagcaa agcgattttt gaaagctatg
    28561 aaatttgttt aataaaaaaa ttcaccagat aatctgatag agactaaccc aattactaac
    28621 agttgtaatt ggtgttagct tacaaattaa ttattgtgtt tagtcaatta caaattgtga
    28681 aacggcacta ataattggaa aggaaaaatg aaatgtctaa agatttacga gagcttaaat
    28741 tgcgaaaaaa gcaatataat caatattttt ctagtttgtt gaataaacat attgaagaag
    28801 gacttgatca tgattttgga aaagatgaat attgtttata ttgcgaacgt tacaatgaaa
    28861 aaatgtctga atatctacag ctgaaaaaag agatacagaa attagagaaa aaagtacatg
    28921 cttggaagta taaagattcc aggtctggtt atgttgaatc tcaaaataag ccaagaaaaa
    28981 agaagcaagc gtatgttcta aagatggtaa atggggaaga gttaattgta ttagcgtaca
    29041 gtgaagaaga ggttcgagaa ctcgttgaaa cacctgtcag gaaaaaggtt gaaacaataa
    29101 atgagataga cgacagccaa tacaatagca tctatattga aacaagtcat ggtggatata
    29161 agaaattagc aactttcctt agaagttcta aagttgggat aatttctaaa aaagacataa
    29221 gtgctgttac cgatagtttt tgtactttat ctgttcctaa agcttatttc caatacgata
    29281 gtaaaagatt tgaacgctta gagaaattct gtagaccgta tactgtattg aaaactaaaa
    29341 aatttaataa aactaaaaga gtttcgatac agttaccgac tggtcaaatc tcattaggtg
    29401 aaaaagacta tctgataaaa gtaggaaaag agttaattat aaaagtaccg gaacacttat
    29461 ttaaagaaaa ttttgagata cgtgaaacct tggtatggaa agaagaaaaa tagtttggaa
    29521 gacatagaat ggtataaggg gaaattgaaa tggcagtaaa taaaatattg caggtattaa
    29581 tcatagacga atttggcgga ggagaatggt ttgatgtgca gtccatagac tttgaagaag
    29641 aagtcgtagt tatagaaaat atttacggcg aagtatactc atattcgctt gaaggtgaga
    29701 atgttgagga tctacggttg attggtgagt agaaaaaagc agaaatatca aaatggagat
    29761 aaaaattaat agcatgtaaa gatagtcatg cttacatgct ttatccaaaa tggtatgcag
    29821 acaaaaatat agctgaaata aacgattatc taactagtat aaaggaacgc aatgcaatta
    29881 attaacaata gacgaaaaat gaaattaaag gagataggaa aatggtagaa gttgaatttg
    29941 gatcaaaaga atggtttgaa gagttaaact caatgattaa gttcccagaa aagtttactt
    30001 tttactacaa taaaagagac aatatcattc aagtagcttt acttgaaact aagggaagat
    30061 tagaaaatac tcgatggagt atgataaaac catcggcact tagatttcat cctaaagact
    30121 tgacagcggt tgtagcggta aaagaggttc aagactcaca agaatattat gaagtagtaa
    30181 aaaatctgaa ggatatttgg tgtaaataat tctaaattga ccagttattt ggtcaaaaat
    30241 agtatgtgat tatttcatcc aatgtggcat cataattggt atggaagggg ataaattatt
    30301 tgaaagaaat agaaggtatt aagaaaagaa atcaggaaag attggaactg ttaaatgaaa
    30361 atagaaatag aatgtttagt tattatgaat ctatgaggtg tttaaataaa tctagaagtg
    30421 aaattataga atcatcaaag tataaacaat tgatggaaga gagagtttct ctcatccaag
    30481 aaatagaaac agagtctatt tttccagatc attctcctaa agtccgattt tataattaaa
    30541 cattaacaaa tgaaacgatg ctaaataggc atcgtttttt atctatttat aaaattaatt
    30601 tatttacaaa atgtgtatcg gtatgtatgg tgaatttgta gataagttga gaaagggtga
    30661 tcttaaatga aattagaagg tagcttacaa aatagaatga tggaaggcag tacaacaaac
    30721 aaggagattg tagttggaat gggagcaacc gagcttctat ataccgacag aaatccttat
    30781 acagtaattg aagtaaaaag caaaaacaga attttggttc aagcggatgg agcaatcaat
    30841 aaagctactt ttccagatca agagtgggaa tatagcagaa atcctgaagg tcaaatattg
    30901 gagttagtta agacaaaaaa tggatggaaa gtgcttaaag aagatattca tttttatata
    30961 ggtgatagag aaaaatacta cgatcctagt ttttaaacaa cctgaagatg agcgaggttt
    31021 tatcctcgct cagaaaggag tatggaggat gttcagtcaa gaagaaatca tcagcaaatc
    31081 gcaaccggat aaaaatggaa ctataatcat gaagaaaaaa atcccttgct atcgttgtag
    31141 cggatcaggt cagtacaagt ttatgtctat ggggaaaatt acctatggca catgttttaa
    31201 gtgcgatggt gatggatttc ttgttgtaac tgaaaaatcc tttacgccag aatatagaac
    31261 taagctaaat gttttaaata aaaaaagagc tgatcgaaaa ataaggatcg caagagagaa
    31321 agaatctcag aaaaattttg atcgttatgg ctttgaaaag ggttatattt acgtggttat
    31381 agagaaaaat agctatacga tcaaagatga actgcatcat caaggagcta cttatgatcc
    31441 tttattaggt tggttttttt aaggaaaaac aagaacaata caaaactcaa aaagtttttg
    31501 tagaagaatt ttctgtaatc aatgatgaag gaattattga gttgaagcta gaagaataca
    31561 gcaaaagaca acaggagatt ttaagtgcga agcgtagaga agagggtgag tttattggta
    31621 caatcgctca acgattggaa ttggatttga aacttaccaa taccgtcacc atagatacac
    31681 aatggggcaa tgtttacctg catttatttg aagatcaaaa ccataattca ttgatttgga
    31741 agacaaataa atttctttat tatgatgaat gggatgttgg agaaataaga aaagttaagg
    31801 cgacaataaa agcgcatgac tactacagag ataccaagca gacttggatt aaaaatgtta
    31861 aaattcaaaa aaatgagtaa gaagggataa aagtatgaaa agagaagaat acaaacaaag
    31921 attaaacgaa ctgcttgaag aggacgaaac attaactcat ggttcgccgg atgaaattct
    31981 atacatgatt gataatatgg taatttttgg tggatatgaa cttggtaata ggtcagttga
    32041 tcataatatt ttagaatttg atgatgtatc atgggaagaa attcttgatt ggggaatttt
    32101 ggcagtacct gaaactaaaa cctatattag tgacactatg gttccttttt ttgaggaatt
    32161 ggattataaa agacttccca aaaatgaaaa tcatatactg ggaggaaact aacaatgtta
    32221 agtgacttac ttattttact gatctatcta ggtggaactg aaattattgc gtattttttg
    32281 cttgtaattg gtgaatatgg tatttccagt gcaatcactc aaaggtttag attaccagta
    32341 agtgaactaa aaaaatgatg agattatcag catatctttt aatgtttttg aatgtggtca
    32401 tgttaatctt tgtagtaatc ggtgtgactt tcaatttaac ggaatagagg gaaatctata
    32461 atggaaaaaa gagaaaagaa tgaacatatt ttttgagtca atattgttga tggtttttgc
    32521 gatcagcgct taccagaaat ctaaaaaaga gtaatgactg tttagtcatc actctttttt
    32581 tgtagggaaa ttgaaatatg tggagcttgt attggtttag ttaggattgc ttggctataa
    32641 ggagctagtt ctttatcaaa accatcaaag taggttttca gtagcgattt aactgatcgc
    32701 tcatcttgtt tgatttggat aatttcagca tccaaatcgg ttgtgaggtc aggagctttt
    32761 gaagcgatta cctgattttt tttatcttcc aactttctta ggctgtttaa caagttgtaa
    32821 aaataatcat tttgactgtt cattccaacg tgagatgcaa ttttaacaga agtttcatcc
    32881 gtattggcat caagtatttc atcaaaagaa ctcattggaa tatcaagtag taacgaggat
    32941 gtttccttta cagcattttt agtttttcca tcttttttgc tcttaacttg agatattttt
    33001 ggatctagtt taggtaaatc acttgtttta tcagtcattt attagctttt cctttctatt
    33061 aatttatgtt attatattat cataataaca taaaaaagaa cactttttgg gggcgtagtt
    33121 attgaaaaaa tctaagagaa agattgccac gttgcttacg ttaatggtgc agtttacagg
    33181 gattgcaatg agtgtaatca caataaatcc gcaagtgtta catgctgatg ggatagctac
    33241 ttatgatgca caatttaact gtactactga aggtagtggg tcaggaacag atagcgatgg
    33301 aaacgatact ggaagtggcg ctgtaacagg tgatgtagcc aaaaatattg aagatattta
    33361 caaatacatg aatggagaat atggcttatc aggtgctagt attgcaggta ttttaggtaa
    33421 ctggaaacaa gaatcaggta ttgatcctcg aacagtagaa gggtattacg gcgatgggca
    33481 gagagaagtt gacttcatca aacaatttac tgatggtcta atgggtattg gctatggtca
    33541 atggacagcc gggcgacata cagcattagt tgattggtct aagaaaaata atggcggttc
    33601 ttggtggact acagaagccc aattggactt tatgttcaaa ggtgatgggg gattcgtagg
    33661 aatattaaaa gattatgctt taaatgcttc tgatgatgta gtagaaaatg cagtaacttt
    33721 tcataaaaac tgggaaattt cagctgattc cgaatcagct gtaatagctg tacgtggtga
    33781 aaatgcaaaa gaaatctgga agtacatgaa aagcaagggt atggacggtg caaaagatga
    33841 aagtaagatc aataaaatat ccggaggttc aagtaccgga gatggatcga ataattcatc
    33901 aagttcagca tcaggaacag tagaagatgc ctgtgcaact acggatgatg ctaattctgg
    33961 ttctggatca attgggaaag aaggaaaaat taacggtaaa aaaggtcaag taatagcaaa
    34021 tatgacttat gaagaagcat taaaaaaata tgggaaagca atcacgctac caaaatttaa
    34081 agaaccagac tggtcaacat caccttttca aggtgaatta caaggacaat gtactgaatt
    34141 aacatgggct tatatgagtc aattatatga tggaaatcaa ccaactttgg gaaatggcgg
    34201 ttacgtttgg gaaagctaca aatcggcagg agcaaaggtg acgaacaaac caattgtagg
    34261 ttatgcgttt agtgctttag atggatggtt atgggctgtt ggatcagcag gacatacagg
    34321 tgtagttata gcggtgtttg acgatggatc atttttgtgc gctaatttca atgttccacc
    34381 tacccaagca ccaacaagag gtgtttcagt aactttgatt gatggtgtgg atgggtcaga
    34441 taatgtgcat ttctttagcg gtgtaggcaa agctaaattt gaaattgaaa aataaaaatt
    34501 tgaatggagg gcgacagaga tgaatagtaa aacgaaagat gcaattatca tttctttgct
    34561 ttctggtatg ctattagcaa tgcttgttgg aattctatat ttcaataagc agaatcaaga
    34621 catagaagct gaaaagcaca gtgtgcaaat tgaaaatgaa ttgaccttct ttaaagaggt
    34681 taaaccaaat gaagtggatg gattgcaaag agatttagaa aatgatattc aagagatgtt
    34741 taaaggatca gaccgaagca aatttgcgaa tcagtcaggt gaagaatttt tgcgaaagtt
    34801 atttattgtg acaggtaagc caccagttac taacgagagt agcgagcaag aaaaaataga
    34861 atactataaa ccttttactt ttaagctaac aaactttgga attaagacat ctagtagtgg
    34921 gttgtatgaa gcattgactg atttcgaagt tcaatacaac ggaaaaaaag tgtatgatac
    34981 cacattaacc atcacactaa ataatgataa gaaagtgact gggggtgctt tttatgcaaa
    35041 atcatgaaat tactactgct aaaaaggcga tcggaatact ttccataatt ttgatccttt
    35101 gttgtgtggt actatttcaa aagaaaaatg cttatgataa taatgtcaaa gaattggaag
    35161 accttaaaag taaacaaatc gaagtagtca agaataacca gaaagtgaaa gctatgcaag
    35221 aagcccaata caaagaattg ggaaatgctg aaatcaagga acaaagtagg aaattcttta
    35281 atttatttta caactggaat tcatgggaaa aatatacgaa gaatatgaag gaaatacaaa
    35341 aagaatttcc tcagatagta aagtctagtc ctgttgatat ctctggcaca atggtaggta
    35401 ctggtaatag tccaatatct agctatactg ctgattacta tacaacaaat caaaaaggta
    35461 aaatggttga attgattaca cagacaagaa atactccaac aacagcaaca acaacaattt
    35521 ggcgtggagt aacaagcata ggagaaaatc aattgtttta cttggaggat ttagatagct
    35581 atgtaagagc agagtaaaat aaaaaaagag ctaacggtac caacgttagc tctttgtgct
    35641 gacgatgata acaaaaccta ccgaaaaagg attgtttcat cacaaacaca aacagaaaag
    35701 aattgataaa aaacccgaac ctcagaattt ttattaatca attcattttg attataataa
    35761 attgagctga acattacaat acgtatatgt tgtaaaacgt aaaaaaagtc aaaagtaaat
    35821 actttcttaa aaagtcaaat aaaactatta aagacaatat atatggttta tttgacataa
    35881 gaaaatggtc tagatgataa ttagaatata gaattgtaga cttaaataaa tcataaaaaa
    35941 ccttctatga taagttatag ctcttaattt taagcagttt tagatataag aaagtaaagt
    36001 gggggagaat aataatggca gatcgtaaat tagaaaagtt attagaagaa acgtgggatc
    36061 caaaagaatt tagtgaattt tttatggaga attttgaaac tgacttagcg gtgattgtta
    36121 aagatgctct tagagagcaa gggtatcctg aaactgcaaa ttatataaac attaatttta
    36181 ctttgtatac tgaaaataga ggaacttggg atttttgggc taacttagca aataaggagt
    36241 taagtgataa atcagataca ggaattcgta acttttttga atcaaacaga gatgattata
    36301 tgtacgctaa caatcaaaat aaattgaact ttagagtaga gtttgatgaa acacctgaag
    36361 aatttataga aagacaaccg cctaaagaaa atgtagcaaa ggtattggaa gatcgttgga
    36421 attcagatga aatagtttca acaattagcg aacaagacgg acaatatgaa ccgctagtag
    36481 aagcggttag agaagagcta agactgaata agtttcctga tgttcaaaat attgatgttt
    36541 ctcaaattga aataaacgtc aatatcacca atagacttga ttatgatagt tgggcagata
    36601 tagcattaga aaaatatatt tactcaacgt taaaagagtt tatcgaaaat agaatgaata
    36661 tcatgtatct acagcatcca cagtatttaa actttggtgt tgaaatagct acacctcttg
    36721 aagaatggaa aatggagcaa gggcttgact agcctttgct ccattttttt attttacaaa
    36781 tgaatacagt tcttcgtctt taccaagaat gattgtttgc ccaactttga gattatcagg
    36841 tgatccttca gcggtttgta aggagaacgt tccattgaac ttatcggata ccgttatagg
    36901 tagctttaat tctgatcctt cctcatcttt gagaattgct gttttccgtt catcaaaata
    36961 aacagtcttt attagataat ttttagtagt ggtttcatca gatttgtctt tgtttttagt
    37021 agtactaatt tctttagaat tagatgtatt ttctatgact atttcgtttt tggtatttgc
    37081 gcttgtattt atttgattga aaattttaat cgacaagatc ccactaagaa tagccaacat
    37141 agaaacaagt gtaattaata ctgataattt cctttttttg ttcatttctt cttaacttcc
    37201 ttttttgttt tgattagtta gatattcctt atctaataag cctttttagg ctattaaatg
    37261 aagataaacc ccaaaaaatt attgcaataa tgatagtgca atggtactat tattataaaa
    37321 taaattttgc gaaaggggta ggtctaaatc gcaaataaaa agaaattgaa cctagacaaa
    37381 tacaacttgt ataccgcaag ggaagcaagt ctaattttgg gtaaaggtag aaattatgtt
    37441 acaaacataa tcaactatta tccaaatcgt ttgcctaaag gttcgttcaa gaaagtgggt
    37501 gacaaaacct atattataac ggaagaagga atagaagcat tgcgatcaca aacagaaaat
    37561 aaaaacaaaa agaaggaatg aatatgaaga aaaattcgct tgctatggtt ttatttgcat
    37621 cagctgtact tgcggggtta tcagtaccag taacctcaca tgctgatgaa tggactgcaa
    37681 acacaccgga tcaaatccaa attacaacag gacaatcaag ttatgcgttc aaaaaaggag
    37741 atactatttg gtcaactgta gagaagctta aaagcttagg ttacaagact actgttgctg
    37801 agtttgccga attgaacaat gttgatttgg caaaaggaga acaacggact atcccgattg
    37861 gacgaacttt caacatcaat aaagatacat taacagttaa ggaagcagat ggcgaagtag
    37921 ttagtcaaac tgttcaaaaa gataaacctg atcctgttga aaatacggag caagagaaca
    37981 aaaaatccga gactacaaaa gaatcggaac caacagcaaa cacttctgat aagacagaaa
    38041 caagtgcttc aagtgttgat ggagcaagtt catctaatac aaataattct acaagtgaga
    38101 aagaagcatc acagggaaca agtgaaagta gcactacgga agctgatact ggaacatcaa
    38161 caaataactc acaatcaaca tcaaatgatg caaatgaatc aaccagtaca tcttctagtg
    38221 atcaatcaca aacaggttca agtgatgaaa ctgacagttc tacttcacca agtaaccccg
    38281 aacaaccaac taatgttgtg ctaggcgttc catttattag tcaaggtaac acaatgcttt
    38341 gcgaaggaac atctttgcta gaagcgttac attataaagg tgttgcaaca aatcaagatt
    38401 taatgacttt tgttaaatca atgccactat ctcctgataa taatccaaat aatggttttt
    38461 ctggtgaatg gagacacaat gtggatggaa cttatcaagg tatgaatccg gctcctgtag
    38521 tttcatgggg tgttgctaat ggcggaaatg ttgtagatat ttctggttca tcggtacaag
    38581 gattaaaaga tgagattgta aatggaaatc ctgtagtagc gtgggtaact tatgcctttg
    38641 aacctgctca acataaatca atgttttggg gcgatgctat ttggaatcga catgtagtag
    38701 ccgttgatgg atttaaagac ggtttttacc atgttgtcga tcctgtgttt ggggcaagtt
    38761 ggattaatgc aggatcattt gaaacagcat ataacgtatc tcaattagcg gtttcggtac
    38821 gttaataaaa gagatcgttt atatactaag tagttaagta tagtctttat ttgtccttgc
    38881 ttaactactt agaaaacttg ttgctcatgg ttggtagaac taaaaggggt gatgctatga
    38941 gtactagagc gttgaaacag cttgctttca acgaaaaaag tgattaatag gtgtggtgat
    39001 tttaacttag gaatgggcgc gaaggtcatt accacaccga catatcgtgg ctcattttct
    39061 tcgcctaact ggtataaaga aggagtaacg agagatgaag catgaaaaaa cgataatttt
    39121 aaaatcaaaa ataatttatt gttttgcgac tttagtaatg gtgttatcta cgcttataat
    39181 gcctttttca gcaataagag ctgaagcaga tgtcacaaaa ccgacaagtg caaaatttac
    39241 agaaactggc gtaaaaacag acggttatat tagggttaat atgccgaatc atccaaatga
    39301 atggatgatt tcaagtcaat ttaaagattc tcatggaaat attggatatt gtatggattc
    39361 agaattgcca tccccaacag gaagtggagc cggaagcttg aagtacaagg gagctggcag
    39421 tgatgagttc tatcgtatgt ttaaaggtgg ttttccatca aaaacagcaa aggaactggg
    39481 tgcaggaaat gatacagaag catggtatgc aacacaatta gtttcatggg ttttagccgg
    39541 aaactttaaa gtttcacaga ttgtatggtc acatccaaac cataccgccg cagaaacagc
    39601 tcgtgtaaaa aaagcatttg aaaaaattta tgactatgct aagaatggaa aagatacgcc
    39661 caacactgag ttttctatca cagcttctaa gacagctgac gaaggaaaat atcacacttt
    39721 cacatataaa acagcatcaa ataagactgg taatgcgaag ctcactttta catcagcaaa
    39781 accagctggt atgaagattt atgatgcaga tggtaaagaa attactaaca acactgtgaa
    39841 attaaattca agttttacta ttaaagtacc tgtgactaca ccaagtggta ctttgtcatt
    39901 taaaggtact gctaatgtta gcacaaccaa tccttttact tttgatggac gaggtgtgta
    39961 tcaagatgcc gtagttatga tcactacttc agaaacaaag gactctaaat ctttgagtgc
    40021 taaatggaca agagctgttg gtcaggtaac agttaagaaa gttgatcaag atggaaatgc
    40081 tttaaaagga gcggagttta ctctaactga caataacaat gctaaatctg ttaagacaac
    40141 cggagatgat gggttagcta cgtttgattt gcaacaaggc ttaacataca gcttagaaga
    40201 aacaaaagtt cctgaaggtt atcaaggttc atttaaaaag gatggtatta ctgttaatac
    40261 cgatggacaa gaatttagtt acactgctac gaacacaatt aaaaaaggta aagtaaaagt
    40321 taaaaaggtt gaccaagatg gaaaaccatt agctaatgct gaatttacct tgacggatga
    40381 ttcatcccaa acacaagcag aaaaaacaga tgaaaacgga cttgcaagct tcgatattgt
    40441 agcaaacaag acctacagcc ttgaagagac cggagtacca actggttata caggcgtatt
    40501 caagcaagaa ggaattaccg ttaaagatga tggacaaact tttgaatata cagctacaaa
    40561 cactttgaaa aaaggtttag taaaagttca taaagtcgat caagatggaa aacctttggc
    40621 aaatgcagag ttcactttaa ccgatgaaaa aggtgcaaca caagtagaaa aaacagatga
    40681 aaatggactt gcaagcttca atattgtagc aaacaagacg tatagcctag aagaaactgg
    40741 agtaccagta ggttacacag gtgcatttaa gcaagagggt atcaccgtta aagacgatgg
    40801 gcaaactttt gaatatacag ctacaaataa tttgaaaaaa ggtgtagtaa aagttcataa
    40861 agtcgatcaa gatggaaaac ctttagcaga tgcagaattc accttaacgg atgaaaaagg
    40921 tgtaaaagaa gttaaaaaga cggatgcaac tggtctggct acgttcaaca ttattgcgaa
    40981 caaaacttac aacttagaag aaacaaaagt accaacaggt tacacaggcg cattcaaaca
    41041 agaaggaatt accgtcaaag atgatggaca agtctttgaa tatactgcta aaaacacttt
    41101 gaaaaaaggt gtgatcaaag ttcataaagt ggatgatcaa gggaaagcat tagcaaacgc
    41161 agaattcact ttgacagacg acaaaggtgt aaaagttgta caaaaaacgg acagcaatgg
    41221 cttggcaaca tttaatattg ttgccaacaa aacgtacaaa atcgaagaaa cacaaaaccc
    41281 taatggttat acagggaaat ggtctaaaga aggcatcacc gttgctgacg atgaacaaac
    41341 ctttgaatat acagtaatta atcaccttgt acctgaaaca gtaagaacag gcggaatcgg
    41401 tacatcagcc ttccttcttg tatttctaat tgcaggattg agtatggtgc tactgtatta
    41461 tcgagaacag cacaaagcaa aataaaaaag tgttaatgga aaagaagtaa atatgaaaaa
    41521 agaaggctga cgtatgaaat caaaaaaaat tttttcaaat ttaatgctat ttggtacttt
    41581 gctaggagtg ggattgggcg caagctcaat ctcttctagc cttggactag gggggcaagt
    41641 agcatatgca caacaaaact ataattatca aggaactgga acgattcata tccataaagt
    41701 aacaaatact aatggggatg ggaaccctgt ctcagatatt gataacaaag ggaaagaaat
    41761 agctttacca aatggtgtaa aacctcttga aggcgttgag ttctcttatg tgaaacttac
    41821 taaagatgaa gctaaatcct tgggatggac ggatagtgat actacaaaag gtcaacatat
    41881 tgatgatgct aaagcacgat tattactaaa caaaaaatac agtgaagtaa gtagaatgaa
    41941 gactgattca caagggaata tagacatacc tatacaagta aatacagacg atttaacaga
    42001 taacttgtat ttgattgttg aaacaggaac agtcaaaggt gtagttgaag aagcgtatcc
    42061 tatgattgtt aacgtacctg aactaaacgg atcagatgat caatacttta attatgatgt
    42121 acatgtctat cctaaaaact atttccaatt aaactcagca gagcttgata aaaaagacga
    42181 agatggaaag gctcttgccg gaactgtttt tgaattgcga aaagatgatg gatctgatca
    42241 ggttgttgga acttataaaa cagacagcac aggtaaatta actgtagatg gtttggaatt
    42301 aggtgactat tatttcctag aaaccgactt gggaacagat gctaataaaa caacctattt
    42361 actagatggt aaaaaattca aatttagcgt taaacgtggg gagactgcta aagtagttct
    42421 tgatgttacc aactacaaac gacctgtaat tactaaggta attgataaag aaaccgttga
    42481 tactggcgaa gatgttcaat atacattgaa accatcaatt cctggtaata ttggtaatta
    42541 cgaaaaatat gttgtcaaag atgttctagg tgcagagtta acttatgatt catcagaagt
    42601 gatcgaagga atgactttag atactgatta cagtatcgaa cgtgacggac aaacgacaaa
    42661 ctatgtcttt actgaatcag gtatggataa gcttcagaaa caatttgatg caggggatcg
    42721 cttctttaca attttgatga acgctcatac taatagtaaa gctaaaatgg atacaccact
    42781 taagaatgat gtttcaacga tctacaacaa tggatatgaa cccgaagacg aaacaccagt
    42841 tgatcacgct tatacaatca ttggtgatca ccaattcatt aaaacagatg gagatacaag
    42901 caaagcattg agtggagcaa aatttgtagt gaagaacaaa attgatccga ataaagttac
    42961 ttacctaaaa caagatccaa caacgaaagc tgttacttgg attgcagata aatctaaagc
    43021 tactgaattc gtttccggat cagacggtaa gttccaaatt gaaggcttgc aatataccta
    43081 tgatgtagat tttgataaac aaggtaatcc aacaatcaca gataaaaaaa tcaatgatta
    43141 tgctcttgaa gaagttgttg ctccttcagg atatacacca actagaaatg atgttccatt
    43201 tgtggtatcg aatgatgatg cttctagcga agtaacagac atcaagaacc ttaaaacacc
    43261 tgaaacagtt cgtacaggtg gaattggaac agtagtattt ctagtggttg caggtgtggc
    43321 aggaacaggg ctatatgttg tctacaaacg agaacaacac aaagcttaat gaaataaaat
    43381 tccctagagt gtttttggct ctagggtttc tttttaaaaa gtgtgtgaaa agtaggtatg
    43441 agcatgaaaa agaagaatat caagttgatc atcttaaaaa ttgggatgtt gctatgttta
    43501 ggagtaggtc tatatcctgt aattactcag gcttatacct actaccaaac tcaacaaaca
    43561 ctaaactcct ataaggaaaa atatgatgaa gcttctgaaa aggagaatga agaagtcttc
    43621 aagagatatt cagaagttaa taggaaacga aaagacacag aacaaacctc agtcacgatt
    43681 cctgaagata ataacaatat tccgtcaaat gtaaatcttc agaaggataa attaggtgaa
    43741 ttagtgggtg aaattcttat accaaagatt aatgtggatt tgccaattta tgatggtgta
    43801 aacgattttc aactatcagc aggagcagga atattaaccg gaactgatta tccaactggt
    43861 gggattggaa accattctgt tatatcagct cattcgggca ttcctaataa aaaatatttt
    43921 acagatttag agttgctcaa acttggtgat aaatttttta ttgatatttc agggaaaaag
    43981 cttgcttatc aagtagatcg gataaaaaca atcctaccaa ccgaatttga ggatttgctt
    44041 cctgtggcag gaaaagatta tgtaacactt atgacatgta cacctgttgg agataattct
    44101 cataggttac tcgttagagg ggttagcata ccttaccaaa aaagtattgt tgagaaagaa
    44161 aagaagaaag aagatttaaa ggtaaaggcg cagatgaact ggtatcctat cgtagttgta
    44221 ggggttttat taataatagc tgtgatagtc attattaaaa aaatagtagc aaagagacga
    44281 ggaatgaaaa atgaagaata aaatactact ttttttgact cttatttgca ctttggtttt
    44341 aacaatttat cctgcaaatc agctctatca tcaattcaaa acaaaagaga atgtggcgga
    44401 aatccaagag aaaattgaga aaaaacaaac tccttcaaaa gaggaagtgg caaaaaaagt
    44461 cgaacaaata aaatcgaaca gcggtaacca aggattagac aatactcaga aaacagacgg
    44521 cggatcattt gatattggtg aagctgaagg aaaggtcaat ccttacacag gagatgtttt
    44581 ttcaaaaaat caaacgaaag attttgaacc atctacctat tcaggggcgg ttggttatgt
    44641 ctatattcca aaaataaatg tgctagagct tttgtttcta ggcgcttcac aggaacattt
    44701 atatagaggt gtggcacaga tgagtgctac tagtctacct ttatcaggta aaggtcatca
    44761 aacagtaata gcaggtcatc gtggcggtta tacgtcacca caatttcttt atgttgatca
    44821 attagtagcc ggagaccaca tttatataga ttatcttggt gaaaaagcag tttatacggt
    44881 tttccgaaca gacgttatta gaaattacgg tcagaattca acactgactg atattcctga
    44941 tttagatatg ttaacacttt atacttgtca tccatatcct cagaactacg atcgtttatt
    45001 agttagaagt ctaagagatg aaaaagcaaa atacatcacg ccacaagtaa cagttggcaa
    45061 taccgcatac gctgatgcca ttgatagcga gtccgtttca gataagacag aaactgttac
    45121 atcttctaat gatttatttg aggatgttga tcgtgccaac aaggaattag atggaaataa
    45181 tgatcttaat attccggaac aaggtagcgt agagatgcaa gacagaacat ttgctgaaaa
    45241 ggcaagttca atattcacag gaattaccaa taaacatcag aaaatgcttt tagtcatttg
    45301 gactgtaata ggagcattag caagtctaaa ggttcttatt cttttaatca aagagtttcg
    45361 aaaagcataa tgaagattat aaaaattgat agagtacagt aaaaagggat tgatactatt
    45421 attgatctct tttttatttt gaatagagct agattcactt ttaaataaaa tcaaaactga
    45481 ttttaattct aaagaaaaag tcaagaaaaa aatacaacaa atttttttat cagaatattt
    45541 atcagaatat tattagaaaa gataaactca aaagcttaat ttaatagggt tattggttgt
    45601 atttagaaat aatgtatgga aaagctataa agaaatagat aagatgtaga aaatcttatt
    45661 tgtgaatgaa aaacaagtca tcgtaaaata ttaataggag gtgtagtaat ggtgggaata
    45721 tcaaaaacag ctttagactc attagctaaa ctatttagta gcaggtttga tagtgcagaa
    45781 tttgttgaat atctaagcca aaacgaaagt ggaaaaactc tgatcgaaac aatgaaaaaa
    45841 gactatttga atgaaaatga ctttccgaca tggacgaata ttgaagatgc tacatgggat
    45901 gtagtgtgta cgatatattc tccttgggta acgattgctg attttgtttt agataaaatt
    45961 ggaggggata cataccctga tgccaaatct cttgctacaa gtgactttaa aacgttctat
    46021 ggttatctaa taggtctaat aggcaatgga atagatttga aagttacgcc aaaacaaaca
    46081 cctgaagaaa ttgaaaaaga aaaaggagag gttcaaatgg cttatgcaaa tgacagagaa
    46141 aaagtaaaat tattggaagg taaattatct gaagaagaac ttggaaaaat ggtgcaagaa
    46201 atcaatgaag acagcaacta ttttcctgaa ttgaaggtat atcaaaatga cgaagatttc
    46261 tttaatgaaa tgtttagtaa tagtccatgg gaagcagtga gtaaaacaaa tttaggagaa
    46321 tggaactttc aagatgatct agttgcattt agcaatgatg ggtatttacg atcatattca
    46381 gaaagtgagt atagagctga attaaaaacg tatgaaacgg atattctgat gagctattta
    46441 aatctattag agagtggtca gggagagtta agagataaag ttgaagaact attaaaagaa
    46501 gagctatagg gattatttca acataaacac aagcagaaaa ctaccaaaca aaacgtacca
    46561 tgcaaaaagt cggttaaacc ggctttttgc tctattatga gaggagatca aaccatgagt
    46621 gcaacaaccg atatggcttt agaagcagta ataaaagata atacaggaaa tgtcgaaaat
    46681 gtagaagact ttagcgatat tgcaatcaat ctttcagcat ggatttcagc tgtaggagaa
    46741 gaaaatatcg aatttgagat caagaatatg gatgacttaa aagcaaaatt tccttttatc
    46801 gcttcgaaac taagtcaatt tgccgaggat aaatcgtgga atgaattagt tagtttttcc
    46861 gaaaaaattt atgatattac gcaagaagat gagtgtgttt catgggaaat gaataatcaa
    46921 tacaagaaaa ttgatgcttt cgtcaaatca cgtatagaag gaacagcttt tgagtttgaa
    46981 ggtatagata ccgcagataa ttggttaaat aaagaatcct ttattaaaag tatagcggat
    47041 gatcttgaaa aacaatggtc taaggaagac tatgcagagt acctaaaaac agaaagagat
    47101 acagaggtga aagaaaaact cactgaggta tgtttggatg aacatattga tcccaatatc
    47161 gtaaaacaag aagactatga agtggttatt gataaagttc ctactgattt tgaggaagtt
    47221 gtaaagtata tagttgaaga agcattatcg caatactctt cagatgagga agtggacgaa
    47281 gaaactgttc gtaccagagt ttggcaactg gtttttgatg acaaagatta taaatatttg
    47341 agtgatcaaa actcggttaa ttggagtgta cgattattaa ttgatcaaaa tgatattgaa
    47401 taaaatagag ctgaaaagct ctattttttt tgataaaaaa actagctatt tttttaaaaa
    47461 taatttggtt caaaatttat ttttttaact tgataatttt ttgccatcct tttttaaatt
    47521 ggctatatat caaggtttat agtggggata aataaaaata catttgacaa aatttacaat
    47581 atagtttatt atatatttat cttattatga taacacaata aaaggaatga tggtatgaaa
    47641 aagaagaagt ttagtcgatc gttgttagga attttagttt tagttgcggt tggtcttagt
    47701 ggcaagggtt actttcagaa taacagcact caggaacatg attttcagat caaaagtagt
    47761 gttcaggtag gtaataaagc agacagtgaa tcaaaagaat ttttagggat acgttatgat
    47821 ccaaacaaat atccaaataa tatcgtaaac attaatgatg ggaaatatac actgacaaaa
    47881 gaagaccatg aagcattatc agaaaaaggc agtcaaacct tttgggtaaa ttatgcagat
    47941 ttagatcaac ttggaagagc aggagatgtt gaagcgttga tcacctatga tgctataaat
    48001 tctcactcat ctaaaaatgt ggaacgtcca tctttcaaaa gttctgtcca tattgcagga
    48061 gaatacaagg atggagtatt tgatcaagag agagatactt gggtcggcaa agattcaaac
    48121 aatgaaatca ctcagctaga aggatataaa ggttatctct ataacaaaag tcattcatta
    48181 gcatggtcgc taggaggaga tatggaggta cacaatttaa cacttggaac gagagcgcaa
    48241 aatgttggga aaaatgatca gaatggaggg atggcttact cagaaacgat tgtacgtgat
    48301 gcaatctata aaaataagaa tgaaaaagta ttgtataaag ttgatccaat ttataaaggg
    48361 aatgaattgg ttcctcgtgg ttctcatgtc gaagctttct cagttaacga taatggaaaa
    48421 acggtaaacc ttaatgttta tgtatttaac aatcaaaaag gaatcaacat caactatcaa
    48481 aatggtactt gggtaagaga ttagaaattg agaaggtgaa gaattggaaa caataagcat
    48541 caatggatta gataaatcag ttgcaaatcg aataaaaaaa ggaaatggct actatcttct
    48601 gaagaagggt aaatattcag ttgctagaga gttagaaaca atgagtatcg tgtatgtagc
    48661 taagaatcat tttgacgtag aacaggctat ttttgatcca gattctgaaa tagggaaatg
    48721 tgttgaatta tcagagaaaa ctgttagtac aaaaggggcg atgatcattg agagagaaat
    48781 gttagacgaa atcagagtaa tcattcctaa agatacgcag atgtgtgagg acagcataag
    48841 tgacgatgaa ccaaaatcag aaagaaaata aggagatatt cagatgagcg aaaaatccat
    48901 tgaattaaag gaatataagc gaagcgatgg agaaaaatat tatcctgtag ccagtttttc
    48961 taaatcagta tatctggttg gacgtgcatt ggtagttggt gcaattggca tatatatttt
    49021 gcattgggta acaaaggttg tacaactgct tgtagatacc ttagtaagta ttcttgtctc
    49081 gttaaatgat gttaacggaa cagatgattt aggattaaaa gaaatgttta aagagttact
    49141 caatgcgttt tttcccaatt atttaagtta ttcatataat gtacaaagct tttttgcaaa
    49201 gctacacttg gtagacatct ctattttagt attagaagca ggaacggtat tctttgttgg
    49261 atatttggtt actttgatgt tcaggcatca ctatggagaa caaagaccat tttttgatga
    49321 tatggaaagt agaaggttga aaagagaagc tctagaagct atggatgtga agtatgatcc
    49381 aaacaagatt ataggagatg aaacgaacaa caaaaaaaga aaacgaaaca aaacgcaatt
    49441 agaatccgat gtgctatcaa cgcttaaaaa tatcaaaatt tctgttcata caagacgtga
    49501 tctaagtgtc aatgaagata ttcgagaata tatcgtaaaa atcccgcaac caaaagggaa
    49561 gaaagttaga gaaacagttt tacgacaaat tcaagattta gggtcgatcc tgacaagagc
    49621 aacaagcgga cgagccaaat ttggtgaaaa agaagatgaa gtttcaggcg attatttcat
    49681 tttccgagca tcagtaaata ttgaaagaga acgtaaggaa agagtaagta ccaaaaacaa
    49741 agaaacggaa agagcaacat cttcaatcgc agtttcaaat tcacaatttt cttttccaat
    49801 caatctcttt gccgataatt ccaaaaatat ccaaaaccaa accgaaaaag ctagaaaata
    49861 tgccgaaact caaaagcaat ctttagaact ttatctatct tctgctgacg tacctgcaag
    49921 tctaacagat atgcacgttg ggaatacatc tattgaatat ttgtttactt tatctcgtac
    49981 cagaaaaatt caactaagct caatgaaaga agaaattgaa acttacttgc atatatcagg
    50041 tgtaatcgtg cggatcaacg cagggcgtat tcaaattact ctaccattag gagaaaatga
    50101 tcgtattcca attgatgtac catcaatgat caatagcgtg ttttaaaaga catcacaaat
    50161 agaaacagaa aatacaaact accagttcac aaacagaaaa gtaccgagaa aagtgaggaa
    50221 tagaaatggc tatgaaatta ttagagaaag tcaaaaagag agccgaaaaa gctgaatcta
    50281 ttttgctaga taaagaacct aatataaagc ttaatggaaa attcagtgtc aatatgttga
    50341 acacaaaggc taaagacccg acagatgcta tttttggaat taagcctgat ggcacaattg
    50401 ctcatttttg catcagcgaa atgccacaca tgttggttgc aggaacgaca ggatcaggga
    50461 aatcagtatt actgaatgaa attcttgtta cagcaatgtg tcactcaacg cctgatgaat
    50521 taaaaatagg aattgtagac ccaaaaaggg ttgaatttgg aagatacaaa aaattgccgt
    50581 tcatgttggc tgatccaatt acagatatgg atgaagctta tgattttttt gaatatcttg
    50641 tgatcttgat gcatgaacgt tacaaactga tggaaaaagc agggttacaa aacatcacgc
    50701 tatataacga atatgccgaa aaaaatggat tagatagatt tccctatgtg atcttattag
    50761 ttgatgaata ttcacagttg gttggaacac ataaagaagt agaaggtttg attgttcaat
    50821 taggacaaat ggcaagggca gcaggtattc atgttatctt agcaacacaa tctcctcgat
    50881 caacagttgt cactggtatt atcaaagcca attttccgtc acgtgtttgc cttatggtag
    50941 caagtgattt agaaagtagg attgtattag atgaaggcgg tggagaaagt ctaagtccaa
    51001 agggagatat gcttattaag cttgttgatg gaagtatggt tagagcgcag ggagcttaca
    51061 tcagtaacaa agaaattgaa acaatcttca atcaccttag aaatactatg ccagaaccag
    51121 aatatgttga ttaccgagca atcgtagctg aaactcgtgg tgagggcggt gaagacgagg
    51181 attttggtgg aattggtaaa gctcctgtaa gaaaatctgc taaaagaaat ttgaacacac
    51241 ctttagcaaa tccatcatct aaagagccat caattgaaaa gaagagtgcg tttgctatta
    51301 agcttgaaaa aaataaagaa gaaaaagcta atcagggagc taagtcacta gaaaaacttc
    51361 agcaagaaaa attagaaaaa ctagaaaaag cattatcatc atcaacttct gaaactcaat
    51421 cttcaaaggg tatagataat ggacaatcaa ttacaactaa aaacaagcct aaaaatagta
    51481 attcaaatct ctcggtaaat gttgttatca caactgataa atctgaaaaa aaacaagtga
    51541 acggaactac ttcacccatc atgcaaaaaa tgataaaggc aaaaaaacag gtgcagaaat
    51601 gattatcatt agttcctttt tgagatggct aacaccatat aaatatacag atgaaatagt
    51661 tgagaagcga gcgaagaaaa aagttaaaaa aacgatgtta actcctaaag aaatgctaga
    51721 tcgtggaata ttgggagtga aggttttaga agtaaaccaa ccgtttgaat tggataatgc
    51781 gagagatagg ttgcttagag ctgaagttga tgtcgcatac ttttatcatg ataaaagcaa
    51841 gcatcaaata gctatcaaat tcaatccaaa atcggcatgg cgataccaag caagagatga
    51901 cctaaagcgt aggaagctga aaccgatgct ctatcctgaa ggaaaagagg catttgatag
    51961 aacccatatt gttcccattg gatttcatgg tacagagtca gataaccgcc tattggtagg
    52021 gtggaacagc tcacaaaata gagttcagat caataaattt gagaagaagg taagaaaatt
    52081 taacgatcgg aaaataatac tttggtttgc caatattcag aagcaaccag atgggacagc
    52141 aaagtgggaa gcggtcatat ttgatgaaga tggcaaaaaa gtaatgtctg aagtatggca
    52201 tgataaagct aaatttgttt ggcagtagag gtgaaaattg tgttaactaa cctaaaacta
    52261 tatagagagg gatttaacga aaaagtaagt atcggtgaat ctattgaata tttaggaaag
    52321 aagtacatta ttattcgtat tcttgaaatt aaaaaacttt attttagtaa atataataat
    52381 ttagcagtta gagttctcgt ccaaaaggtt ggaaatccaa gtgactatag aagtgattac
    52441 cataactata aaacagaatc atctgtaatt aagcgttata atcaatcaaa aaatgatgag
    52501 agaatattca aagtaggaga aattattatt tctaagtatg ggatagcata cgaaatagtt
    52561 tctattaaaa aattttatta tgaatttgtt gatttggttg tagaatattc tgttcgattg
    52621 atcgttccgt ggagtaaaga agaaattaat gaggcattaa aacatgaacg aaaaagtaca
    52681 ttcaaagttt tagaaggtga aaaaaagtga aaacagacct tactaggcaa gctgagaagt
    52741 gcttatggca tgaaacaaat cgcatgggtg tatttggttg tttcgaagtc actatcggtt
    52801 gggatggcag tgaaagagta gattatataa cttattcagt agataacaca gttcgatgtt
    52861 atgagatcaa agttacttta gctgatttaa aaagcaaggc gaaacagact tttatcggtg
    52921 attataacta tttagttgtt actagtgatt tgtgggagaa aatgcaacaa gacgataaac
    52981 ttatgcggaa atattactat caaggcgtat acgtgttcaa tgaaaaatat cctagcataa
    53041 taagtgttaa gaaagcaagg aaacaaaaag tatcgctagg tacaagatca actgtattag
    53101 aaagcatggt tcgttctatg aatcgtgaag ttaagaaact ctataaagta aaaccatttt
    53161 gggagatagc agaggtggaa aaaggatgat tcaaacattt gcaaaaatga gtagaagtgc
    53221 ttggattgaa aagctggaaa atgatttgag tgttatgcga ttagctccaa agaaattcaa
    53281 acgagagatt gcagaaaaag aagcaatttt gtcggtattg aatgcggtag aactggacga
    53341 accgaaaaag tcagttgatg tacctgaaaa tgtagcagag ttactagatt attatcgtaa
    53401 ttcgtcagat gtcgatttgt tagctctgat attaacattt cacgattggt attactgtca
    53461 aaatgaagat actcagcatg ataaacatga taaagcagtt gactggttaa tagagaatcc
    53521 agaaaagttc atgcgtgctt ggctagatgg ctatgatagc aagaaaaagc cactggaaag
    53581 taatgaggaa acgtatttaa cggcagaaca atatgactat gctagaaaaa caggagattg
    53641 ggaatctggt aagactttca atcacagaaa agatcaacca aaaattagtt tttcagatat
    53701 agccgcaatt atcgaaggta tctactatgg acaagccgat gaagagatct tttctataca
    53761 agatttatta gaatttttga acaaaaataa ggatagcttt gtagaactaa ctgattatga
    53821 ggaggataca gcaaatggaa aattatgatc caaatatgcg atggggtaca catacgctta
    53881 aagtttcttt tcaacgttgg gattacaagg gatttgtgac ttttagaaaa gctggaaatt
    53941 gtaaaggatt agatgtctta gcgttggatg aagactatct atatgaccat ccattgacgg
    54001 ataatccaat cggatttgga ttgcttcctg aagatgatga gggcaatgaa tggttcaaaa
    54061 tgattcttac aaacgataaa ggtgatcaat tatttgtaga agatacttgg tcatatttga
    54121 gtgaatatat tgttagcatt aaaatcattg attttgtagc agataaagaa aaagagattg
    54181 gagaaggtaa atctaattac tagctaatga atagcaactt tggaggataa gtcaaaagaa
    54241 taaaaaaaga atactgtgtg tcattgcagg gatgtatctt tgcatgatag tatctgcggt
    54301 taccatttat tggttaggaa atcagcaaaa cagtttaatt gttgatctgg gggagttaaa
    54361 ggttggatta cgaatgacta gatggctttt attagctcaa acagttggtt tagccatatt
    54421 gacttggata tgtgtggaaa aaataacatc taataataat caagagattg ttgaatcaac
    54481 aaacctaaga ataactgaac aagcaattga aaagcaaaaa gacaaagaaa aaaaggaaat
    54541 aatgtcaatt tatttatcta gtggagcatc attttttcat gaaatagatt cgatgaaact
    54601 gagtagtcaa gaaatcattg atagatggaa aaacatgcct ctaggtggtg agttaatcgt
    54661 tgaagatagt gatggttggt cagcttataa gaaggacgag attgtagcta tcacgatttt
    54721 gtttgaatag taatatatta ccactagata atctgaatat gttgatctgc tagtgacgta
    54781 ccaaatgcgt ttaatagaac cttggtcaca ggcagaaatt gataaagcag taaaattgaa
    54841 ccgattatca aaatttaacg tattaggaaa tgccttttaa aaatcgcaat acacaaacag
    54901 aaaaatacca aaaaattagc aatgaacgta ggtaagaaca tgacaataaa taataataac
    54961 cctaacaaat ataatgctct tgtccaatgc tatatcgaaa acaaaattac aatgcaagaa
    55021 gtcgctgatg aattaggcaa atcaaaaagc ctagtatcac acgactttaa gcacaatgtt
    55081 tttccgaacc cgattgagct gaggaaaaaa tttcaaaaga gagtttatca agaaataggg
    55141 aagtggattg atgaagggaa tgcaattgac cctttaattg aaaaatatcc ttttttaaaa
    55201 agcaaaaata aaattcaaag gttaattcgt caaggcgata ttcaagctaa agaacctgtt
    55261 ttgacaacca atgatttggc taaaataaat cttcataaac agattattga agactttgaa
    55321 aaaaatcttt caacaactga aattttaaaa aaatacaata ttccgagagg aaagctaaca
    55381 tcgactcttt ttagagaata tggagaatcg gcagttacta aagcaaagga agtagcgaat
    55441 gagagaaaaa aacaaaaata gtagtcgata cttagtagcg actgtagttt ttgtttgtgt
    55501 attgattttc ctgtttgatt ttttacagat tggaaaaagt ataattggaa atacattgag
    55561 tgcaaaggaa atggttgctt taggtggttt gtatgaagga catttgttcc cgaatatatt
    55621 catttctatc gtttctcata ttaacttgta ccatttaatt tctaatttat tgttcttagt
    55681 agttcttgaa gaagcactga atgatcagta tgagtggtta acattattga tcgttttaat
    55741 catatcagga tttctaggaa gcttagttcc ttttctgcta caaagcaaca tcgtaagtat
    55801 ggggcttagt ggaggtattt ttggatggat tgctttattt gcgattgcat acatccattt
    55861 tgatagcaag gaacatttat tactaagtgt ttttgtatta ttgataatcg gcattttatt
    55921 ggtatctact tttgaatcag gcgaggcaaa tgtcttgtca catgtaatcg gatttgtctg
    55981 tggaatgatc ttgggattta ttctaaagaa cgtttcattg atcaaacaaa agaattaaaa
    56041 gggagtgcta aaaatgccaa aaagaaaaga aaagaaaatt ccagtgtttt tgtctgtctc
    56101 agaaatgtta tcacttcaaa tactgttaag aaaaaagatt gaaacaatag acgaagaagt
    56161 tagaaataaa agggctatgt acgaacaacg tgaagcgcta agagaacgaa tccactattt
    56221 tgatgatata cacactaaaa tctatgaagc acgtacaaat cacgaagacg aaagtaaatt
    56281 aggattagct caacaacgga tacttgaatg gcttaatacg aatactgatc aagaaccgtt
    56341 aagagtgatt agtaatcttt ttgaatttgg aacgaagcat tggtttaatg ctgtagagaa
    56401 ggatgctgac ttacaagaag cgtttgatac gctaagtaag gatagcaaat ccatgcgaga
    56461 tttattgatt acttatctaa atgagcatga gtttgaacaa acgaaaacca aaaagaaaaa
    56521 taaagaatag aaagttgtga tgaatcatgc tattaaccct gttaggttat ttatgtttaa
    56581 ttcttgcttt ttttggggca atcgctataa ttattggtca atttcaaaca aataatccga
    56641 ttatgcgtaa cataggcatt ggaattgtga ttgtaacctt tattgtgttt aatgccacta
    56701 agatttttgg aagtaacgat aaacaatttg gtatatcggg agttaataat agttatgctc
    56761 cagattcttt gggaagggta gtaatagatg gaacatttga aaatgtaacg agttataaaa
    56821 atgtttcgct gacagtgaag gaagatggca agaaagcatc agacgacgtt ctcgctacta
    56881 ttaagccgtc tcaatcacaa tttgaagtgt tttatacagt taaagagaat agccctgtac
    56941 acaagctgac attggttttt aacgttgatg gagaagaata ctataaagat gtaaaaataa
    57001 ataaaacatc aacgaaaaag attatcgaat cagcgaaaaa agaagtagct acagaagaaa
    57061 gtacaactga atcaagttct actgtcgaag cggaactacc agataaaatt gattttgatc
    57121 ctgaaaaagt caaatcgttt gaatctgttt ctggttctat ggctgatcgg tttaacactg
    57181 aagtcttcaa agctatcaaa actgttaaat tggatactga aaagcaaatg attaatgtta
    57241 ccttattcaa ttcagttgaa tctatggatc aggataaaaa agttacggtt gcaagagaac
    57301 taggaaaaag agtaattggt ttgtatcgtg gtactgctaa accagattca gacggtgcag
    57361 atttgccagt tcatgtagtt tatgaagacg gtaaagtttt tggagattct acagcaaacg
    57421 aagcattaac gattaaattg gctaaatagc cagaaagtta taataaacaa atggtgtcac
    57481 accaataata tataggtgtg acaccttgga gatgatagct gatggtagta aataaagaaa
    57541 aagttagaaa gtatgtgact ttaaaaatag cttctgttaa atatttagaa aagcgagcta
    57601 aagaagaaga aagagcaaga ggtaagaaag taacagtttc agagttgtta gaagaattga
    57661 tcgagaatga tcaaacaata agacgtgcat ttactaatag gtctatcaga taacaatata
    57721 attaataaaa aagaaagagt gatttggtct tagactaaat cactcttttt atataaagtt
    57781 tctttacact cattccgaat aatgttaaaa ttctttatat gatatatagt tccttgtcag
    57841 aggaa
//
LOCUS       DADQCX010000005        55897 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.005, whole genome shotgun sequence.
ACCESSION   DADQCX010000005 DADQCX010000000
VERSION     DADQCX010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.005"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(5..586)
                     /locus_tag="J8R83_000254"
     CDS             complement(5..586)
                     /locus_tag="J8R83_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9573417.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(719..1402)
                     /gene="rpiA"
                     /locus_tag="J8R83_000255"
     CDS             complement(719..1402)
                     /gene="rpiA"
                     /locus_tag="J8R83_000255"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAZ9573418.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            1721..2134
                     /gene="rpsL"
                     /locus_tag="J8R83_000256"
     CDS             1721..2134
                     /gene="rpsL"
                     /locus_tag="J8R83_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAZ9573419.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            2218..2688
                     /gene="rpsG"
                     /locus_tag="J8R83_000257"
     CDS             2218..2688
                     /gene="rpsG"
                     /locus_tag="J8R83_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAZ9573420.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            2782..4869
                     /gene="fusA"
                     /locus_tag="J8R83_000258"
     CDS             2782..4869
                     /gene="fusA"
                     /locus_tag="J8R83_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAZ9573421.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5041..6228
                     /gene="tuf"
                     /locus_tag="J8R83_000259"
     CDS             5041..6228
                     /gene="tuf"
                     /locus_tag="J8R83_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAZ9573422.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            6635..6943
                     /gene="rpsJ"
                     /locus_tag="J8R83_000260"
     CDS             6635..6943
                     /gene="rpsJ"
                     /locus_tag="J8R83_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAZ9573423.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            6974..7603
                     /gene="rplC"
                     /locus_tag="J8R83_000261"
     CDS             6974..7603
                     /gene="rplC"
                     /locus_tag="J8R83_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAZ9573424.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            7631..8254
                     /gene="rplD"
                     /locus_tag="J8R83_000262"
     CDS             7631..8254
                     /gene="rplD"
                     /locus_tag="J8R83_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAZ9573425.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            8254..8544
                     /gene="rplW"
                     /locus_tag="J8R83_000263"
     CDS             8254..8544
                     /gene="rplW"
                     /locus_tag="J8R83_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAZ9573426.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            8583..9416
                     /gene="rplB"
                     /locus_tag="J8R83_000264"
     CDS             8583..9416
                     /gene="rplB"
                     /locus_tag="J8R83_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAZ9573427.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            9459..9737
                     /gene="rpsS"
                     /locus_tag="J8R83_000265"
     CDS             9459..9737
                     /gene="rpsS"
                     /locus_tag="J8R83_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAZ9573428.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            9760..10107
                     /gene="rplV"
                     /locus_tag="J8R83_000266"
     CDS             9760..10107
                     /gene="rplV"
                     /locus_tag="J8R83_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAZ9573429.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            10121..10777
                     /gene="rpsC"
                     /locus_tag="J8R83_000267"
     CDS             10121..10777
                     /gene="rpsC"
                     /locus_tag="J8R83_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAZ9573430.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            10780..11214
                     /gene="rplP"
                     /locus_tag="J8R83_000268"
     CDS             10780..11214
                     /gene="rplP"
                     /locus_tag="J8R83_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAZ9573431.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            11204..11392
                     /gene="rpmC"
                     /locus_tag="J8R83_000269"
     CDS             11204..11392
                     /gene="rpmC"
                     /locus_tag="J8R83_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAZ9573432.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            11417..11683
                     /gene="rpsQ"
                     /locus_tag="J8R83_000270"
     CDS             11417..11683
                     /gene="rpsQ"
                     /locus_tag="J8R83_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAZ9573433.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            11741..12109
                     /gene="rplN"
                     /locus_tag="J8R83_000271"
     CDS             11741..12109
                     /gene="rplN"
                     /locus_tag="J8R83_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAZ9573434.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            12146..12454
                     /gene="rplX"
                     /locus_tag="J8R83_000272"
     CDS             12146..12454
                     /gene="rplX"
                     /locus_tag="J8R83_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAZ9573435.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            12482..13021
                     /gene="rplE"
                     /locus_tag="J8R83_000273"
     CDS             12482..13021
                     /gene="rplE"
                     /locus_tag="J8R83_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAZ9573436.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13040..13225
                     /locus_tag="J8R83_000274"
     CDS             13040..13225
                     /locus_tag="J8R83_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAZ9573437.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            13261..13659
                     /gene="rpsH"
                     /locus_tag="J8R83_000275"
     CDS             13261..13659
                     /gene="rpsH"
                     /locus_tag="J8R83_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAZ9573438.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            13691..14227
                     /gene="rplF"
                     /locus_tag="J8R83_000276"
     CDS             13691..14227
                     /gene="rplF"
                     /locus_tag="J8R83_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAZ9573439.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            14388..14744
                     /gene="rplR"
                     /locus_tag="J8R83_000277"
     CDS             14388..14744
                     /gene="rplR"
                     /locus_tag="J8R83_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAZ9573440.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            14765..15265
                     /gene="rpsE"
                     /locus_tag="J8R83_000278"
     CDS             14765..15265
                     /gene="rpsE"
                     /locus_tag="J8R83_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAZ9573441.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            15280..15459
                     /gene="rpmD"
                     /locus_tag="J8R83_000279"
     CDS             15280..15459
                     /gene="rpmD"
                     /locus_tag="J8R83_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAZ9573442.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            15503..15943
                     /gene="rplO"
                     /locus_tag="J8R83_000280"
     CDS             15503..15943
                     /gene="rplO"
                     /locus_tag="J8R83_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAZ9573443.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            15943..17238
                     /gene="secY"
                     /locus_tag="J8R83_000281"
     CDS             15943..17238
                     /gene="secY"
                     /locus_tag="J8R83_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAZ9573444.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            17300..17947
                     /locus_tag="J8R83_000282"
     CDS             17300..17947
                     /locus_tag="J8R83_000282"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAZ9573445.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            18138..18356
                     /gene="infA"
                     /locus_tag="J8R83_000283"
     CDS             18138..18356
                     /gene="infA"
                     /locus_tag="J8R83_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAZ9573446.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            18389..18505
                     /gene="rpmJ"
                     /locus_tag="J8R83_000284"
     CDS             18389..18505
                     /gene="rpmJ"
                     /locus_tag="J8R83_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAZ9573447.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            18523..18888
                     /gene="rpsM"
                     /locus_tag="J8R83_000285"
     CDS             18523..18888
                     /gene="rpsM"
                     /locus_tag="J8R83_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAZ9573448.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            18916..19305
                     /gene="rpsK"
                     /locus_tag="J8R83_000286"
     CDS             18916..19305
                     /gene="rpsK"
                     /locus_tag="J8R83_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAZ9573449.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            19385..20323
                     /locus_tag="J8R83_000287"
     CDS             19385..20323
                     /locus_tag="J8R83_000287"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAZ9573450.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            20351..20731
                     /gene="rplQ"
                     /locus_tag="J8R83_000288"
     CDS             20351..20731
                     /gene="rplQ"
                     /locus_tag="J8R83_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAZ9573451.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21003..21842
                     /locus_tag="J8R83_000289"
     CDS             21003..21842
                     /locus_tag="J8R83_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9573452.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            21818..22687
                     /locus_tag="J8R83_000290"
     CDS             21818..22687
                     /locus_tag="J8R83_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9573453.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            22677..23474
                     /locus_tag="J8R83_000291"
     CDS             22677..23474
                     /locus_tag="J8R83_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAZ9573454.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            23677..24423
                     /gene="truA"
                     /locus_tag="J8R83_000292"
     CDS             23677..24423
                     /gene="truA"
                     /locus_tag="J8R83_000292"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAZ9573455.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(24878..27547)
                     /locus_tag="J8R83_000293"
     CDS             complement(24878..27547)
                     /locus_tag="J8R83_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAZ9573456.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(27785..27973)
                     /locus_tag="J8R83_000294"
     CDS             complement(27785..27973)
                     /locus_tag="J8R83_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAZ9573457.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            28243..28605
                     /locus_tag="J8R83_000295"
     CDS             28243..28605
                     /locus_tag="J8R83_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9573458.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            28657..30339
                     /locus_tag="J8R83_000296"
     CDS             28657..30339
                     /locus_tag="J8R83_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAZ9573459.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            30456..32492
                     /gene="recG"
                     /locus_tag="J8R83_000297"
     CDS             30456..32492
                     /gene="recG"
                     /locus_tag="J8R83_000297"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAZ9573460.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            32541..33542
                     /gene="plsX"
                     /locus_tag="J8R83_000298"
     CDS             32541..33542
                     /gene="plsX"
                     /locus_tag="J8R83_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAZ9573461.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            33664..33906
                     /gene="acpP"
                     /locus_tag="J8R83_000299"
     CDS             33664..33906
                     /gene="acpP"
                     /locus_tag="J8R83_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAZ9573462.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            34174..35178
                     /locus_tag="J8R83_000300"
     CDS             34174..35178
                     /locus_tag="J8R83_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573463.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            35179..36123
                     /locus_tag="J8R83_000301"
     CDS             35179..36123
                     /locus_tag="J8R83_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573464.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            36123..37085
                     /locus_tag="J8R83_000302"
     CDS             36123..37085
                     /locus_tag="J8R83_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573465.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            37112..38026
                     /locus_tag="J8R83_000303"
     CDS             37112..38026
                     /locus_tag="J8R83_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573466.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            38052..39833
                     /locus_tag="J8R83_000304"
     CDS             38052..39833
                     /locus_tag="J8R83_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9573467.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            40181..40867
                     /locus_tag="J8R83_000305"
     CDS             40181..40867
                     /locus_tag="J8R83_000305"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAZ9573468.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            40887..44468
                     /gene="smc"
                     /locus_tag="J8R83_000306"
     CDS             40887..44468
                     /gene="smc"
                     /locus_tag="J8R83_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAZ9573469.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            44477..45286
                     /locus_tag="J8R83_000307"
     CDS             44477..45286
                     /locus_tag="J8R83_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9573470.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            45297..46295
                     /gene="ftsY"
                     /locus_tag="J8R83_000308"
     CDS             45297..46295
                     /gene="ftsY"
                     /locus_tag="J8R83_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAZ9573471.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            46482..48749
                     /gene="gshAB"
                     /locus_tag="J8R83_000309"
     CDS             46482..48749
                     /gene="gshAB"
                     /locus_tag="J8R83_000309"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAZ9573472.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(48838..49290)
                     /locus_tag="J8R83_000310"
     CDS             complement(48838..49290)
                     /locus_tag="J8R83_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAZ9573473.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            49440..50390
                     /locus_tag="J8R83_000311"
     CDS             49440..50390
                     /locus_tag="J8R83_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAZ9573474.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            50383..51342
                     /locus_tag="J8R83_000312"
     CDS             50383..51342
                     /locus_tag="J8R83_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAZ9573475.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            51339..52094
                     /locus_tag="J8R83_000313"
     CDS             51339..52094
                     /locus_tag="J8R83_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9573476.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            52117..53070
                     /locus_tag="J8R83_000314"
     CDS             52117..53070
                     /locus_tag="J8R83_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9573477.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(53714..54010)
                     /locus_tag="J8R83_000315"
     CDS             complement(53714..54010)
                     /locus_tag="J8R83_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAZ9573478.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            54365..54721
                     /locus_tag="J8R83_000316"
     CDS             54365..54721
                     /locus_tag="J8R83_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAZ9573479.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            54731..55630
                     /locus_tag="J8R83_000317"
     CDS             54731..55630
                     /locus_tag="J8R83_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAZ9573480.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        18377 a        10107 c        11999 g        15414 t
ORIGIN      
        1 ggtattagat gcataattgc tcgatttctt tttcaggtaa attgatatat ttataacatg
       61 ttccaactga aacaccgcat tttgaagaaa taaattggat cgtttctttt ttttcataat
      121 agagacgtcg gatttttttg atcgtttttg catcgatttt tggtcttccg ccgatttttc
      181 cttttttacg agcttcatct aatccaacta atgtacgttc tttgatcaat gcgcactcca
      241 tgtttgctag gttttccatt aattggaaat agatttttcc catttcgcgc gtatcgattc
      301 cttcatcaag actaatcaag tgcagcccgc gatctttgaa taattgcgtg agttctgtta
      361 attgccgcgt agatttgcct aatcgatgaa gttggcaaat gactagtgca tcgccttgtt
      421 gcatgtcagc gatcactgac tccaaatgaa cagcagtaga atcattttgt tccacttcat
      481 atgtctcatg gaaaatttct tgacaaccaa agtcagataa ttgatcaacc tgagttgtta
      541 aatcaacgtc atttatggtt gtgcgtgcat aaccaataat tttcatggtg attcctttct
      601 agcagtgatt ttctaactgg atataacagt aaaaatgtag cataaagtac gtcaaaaaga
      661 tagttttttc gcaaattttc cgctgtcttt ttttattgga tgatcaagca gtttttcttt
      721 atttacgacg gattgcgtca agaatctcaa cgcctttttc tgagccgaca actactttag
      781 aaaccatgtt taggaaaagc ccatgttcta ctaccccaac aagttcatct aaataggtag
      841 ctaagctttc tggctgttcg atgacttcta gatgcagatc aatgatgtaa tgaccaccat
      901 ctgtggttaa gacttctccg ttttcgtctg tacgcaagac gggttggaat cttttttctt
      961 caaaaatatg aagtagctgt tgggagccat aagggatcac ttcaactggg agtgggaact
     1021 tcccaagttt atcgactaat ttagaagaat caacgatcca aatcgtttct tttgagtacg
     1081 tagcgactat tttctcgaaa agcaaagcag cgccgccgcc tttgatccct tgaaaatcag
     1141 cactgatttc atcagcaccg tctattgtca aatcgactac ggggacttca tcaatactct
     1201 ttaacggtat tcctaatttt tccgcttgtt cttttgtcgc atttgaagta gtaactcctg
     1261 tgatacgtaa accttcttca cgcatacggc gaccaatctc ttctaccata taataggcgg
     1321 ttgaaccggt cccgagacct acgatcatcc cgtcctttac gaatttcgcg gcttcaatgc
     1381 cagctaattg ttttaaattc atctttgcgt ccaccttttt ttagtttgag catcgtgctt
     1441 tcctcactat tttagcgtga tttacggtaa aaagatacca ttctttttta ttccaataaa
     1501 gctttttcaa aaaaaattgc atctcttgtt gacatgtttt ttcattcgtg atattctaac
     1561 aaaggtgctt tatctacagg tttctgtgaa gaaacgtgct gactgtttat caaagcatat
     1621 ttgataagga tgcagacatt gcatttattt tttatcacaa aaaaagaacc acctggatgt
     1681 gtggaactag acgcaaatcg tgggaaggag gaaacaagga atgcctacaa ttaaccaatt
     1741 agtacgtaaa cctcgtaaat caaaggtgga aaaatctaat tcacctgctt tgaacaaagg
     1801 atataacagc tttaagaaaa ctcaaactaa cgtaaactca cctcaaaaac gtggggtagc
     1861 aactcgtgtg ggtacaatga cacctaaaaa accgaactca gctttacgta aatatgcacg
     1921 tgttcgtttg tcaaacttaa ttgaagttac tgcttatatc ccagggattg gtcataactt
     1981 acaagaacac agtgttgtat tattacgcgg tggtcgtgta aaagacttac caggggtacg
     2041 ttaccatatc gttcgcggtg ctttagatac tgctggtgtt aacgaccgta aacaaagccg
     2101 ttctaaatac ggaactaaaa aacctaaagc ttaattttaa ttattaaaca aatgaaactt
     2161 gcttctacta tatagaagta attactatga acaatatttc ggaaggagga gttacggatg
     2221 ccacgtaaag gtcctgttgc aaaacgtgat gttttaccag atcctattta taactcaaaa
     2281 ttagtaactc gcttgatcaa ccgtgtaatg gttgacggaa aacgcgggat tgcagctaac
     2341 attatctata atgcctttga cttgatcaaa gaatctacag gtaacgatcc attagaagtg
     2401 tttgaacaag caatgaaaaa cgttcaacct gttcttgaag ttaaagcacg tcgtgttggg
     2461 ggttcaaact accaagtacc agttgaagtt cgccctgaac gccgcgttac tctaggtctt
     2521 cgttgggtag taaactacgc tcgcttgcgc ggtgaacaca caatggaaga acgcttagca
     2581 aaagaaatca tggatgctgc aaacaacaca ggtgcttctg ttaaaaaacg tgaagacact
     2641 cataaaatgg ctgatgccaa ccgtgcgttt gctcactatc gctggtaaga ttctctctgt
     2701 ttggtcggct tttataagtc gacctcagat agtgtcctta tttttagcaa ctagatagta
     2761 aagagaggag aaacaaggag aatgaccaga gaattttctt tacaaaacac tcgtaatatc
     2821 ggtatcatgg cccacatcga tgctggtaaa acgactgcta ctgaacgtat cttgtactat
     2881 actggtaaaa tccataaaat tggtgaaact catgaaggag cttcacaaat ggactggatg
     2941 gaacaagaac aagaacgtgg tattacgatc acttctgctg ctactacagc acaatggaag
     3001 ggtcaccgaa tcaacatcat cgacacacca ggacacgtag acttcacagt tgaagttgaa
     3061 cgttcattgc gtgtacttga tggtgctgta actgttcttg atgcacaatc aggtgttgaa
     3121 cctcaaactg aaacagtttg gcgtcaagca acaacttatg gtgtacctcg tatcgtattt
     3181 gcaaacaaaa tggacaagat cggtgctgac ttcttatatt cagtatcaac tttacatgac
     3241 cgtttgcaag caaacgctca cccaatccaa ttaccaattg gtgcggaaga cgacttcaca
     3301 ggaattatcg accttgtaac aatgaaggct gaaatgtata caaacgatct tggaacagag
     3361 atcgaagaaa cagaaattcc tgaagaatac cgcgaattag ctgaagaatg gcgcgaaaaa
     3421 ttggttgaag ctgtagctga aactgatgaa gaacttactt tgaaatactt agaaggtgaa
     3481 gaaatcactg aagctgagtt aaaagaaggt atccgccgcg caacagttaa cgtagaattc
     3541 tacccagtac tatgtggttc agcatttaag aacaaagggg ttcaattact attggacgct
     3601 gttcttgatt acttgccatc accgttagat atcccagcta tcaaagggat tgaccctaaa
     3661 actgatgaag aagtagaacg tcctgcagac gacagcgctc ctttctcagc tttagcattt
     3721 aaagttatga ctgacccatt cgtaggtcgt ttaactttct tccgtgtgta ctctggtgtt
     3781 ttacaatcag gttcatacgt acaaaacgca acaaaaggca aacgtgaacg tgttggtcgt
     3841 atcctacaga tgcatgccaa ctctcgttca gaaatctctg aagtttacgc tggagatatc
     3901 gctgctgctg ttggtttgaa agacacaact actggggaca cactatgtga tgaaaagagt
     3961 ctagttattc ttgaatccat ggaattccca gaaccagtta tccaagtcgc tattgaacct
     4021 aaatcaaaag ctgaccaaga taaaatgggt gtggctttac aaaaactatc tgaagaagat
     4081 cctactttcc gtgctgaaac aaacgtggaa acaggcgaaa caatcatcgc tggtatgggt
     4141 gaacttcact tagatatcat cgttgaccgt atgcgtcgtg aattcaaagt tgaagctaac
     4201 gtaggtgcgc ctcaagtatc ttaccgtgaa actttccgtg ctggcactca agccgaaggt
     4261 aagtttgtac gtcagtctgg tggtaaaggt caatacggtc acgtatggat tgaatttaca
     4321 ccaaatgaag aaggtgctgg tttcgaattt gaaaatgcga tcgtcggtgg ggttgttcct
     4381 cgtgaataca ttccagctgt tgaaactggt ttgaaagatg ctatggaaaa tggtgtctta
     4441 gctggctatc cattagtaga tatcaaagct aaactttacg atggttcata ccatgatgtc
     4501 gattcaaatg aaactgcctt ccgtgttgct gcttctatgg cattacgtgc agcagctaag
     4561 aaagctaatc cagtaatcct tgaaccaatc atggctgtag aagttgttat ccctgaagat
     4621 tatttaggtg atgttatggg tcacgtaact gctcgtcgtg gacgtgttga aggtatggaa
     4681 gctcgcgctg gcggccaaca agttgttcgt gcgatggttc cacttgctga aatgtttggt
     4741 tatgctacaa ctcttcgttc tgctactcaa ggtcgtggta catttacaat gacatttgac
     4801 cactacgaag atgtaccaaa atcagtacaa gaagaaatca ttaagaaaaa cggcggaaaa
     4861 gctgaataat ttcttgaaac cggatagtcc tgcaaagaga ttatccaaag agactatatt
     4921 tttaatatag tttcgtgtaa aataattatc gatgatatgg gcatgtggtg taccttgtgt
     4981 acatcatata cctatcagac aaataaaaaa tatattgtat ttttaggagg acattttaaa
     5041 atggcaaaag aaaaatttga ccgttctaaa ccacacgtta acattggtac tatcggacac
     5101 gttgaccatg gtaaaactac attaacagct gcaatcacaa ctgtactatc taagaaaaac
     5161 ggcggccaag ctatggctta cgatcaaatc gatggtgctc cagaagaacg cgaacgcgga
     5221 atcacaatct caacagctca cgttgagtat gaaacagata cacgccacta cgctcacgtt
     5281 gactgcccag gacacgcgga ttacgttaaa aacatgatca ctggtgctgc tcaaatggac
     5341 ggagctatct tggtagtttc tgctgctgac ggcccaatgc ctcaaactcg tgaacacatc
     5401 ctattgtctc gtcaagttgg tgttccttac atcgttgtat tcttgaacaa agtagacatg
     5461 gttgatgacg aagaattact agaattagtt gaaatggaag ttcgtgacct attaacagaa
     5521 tacgaattcc ctggtgacga tgttcctgta gttgctggat cagctttgaa agctctagaa
     5581 ggcgacgctt catacgaaga aaaaattctt gaattaatgg ctgcagttga cgaatacatc
     5641 ccaactccag aacgtgacaa cgacaaacca ttcatgatgc cagttgaaga cgtgttctca
     5701 attactggac gtggtactgt tgctacaggt cgtgttgaac gtggacaagt tcgcgttggt
     5761 gacgaagttg aagttgttgg tattgctgaa gaaacttcaa aaacaacagt tactggtgtt
     5821 gaaatgttcc gtaaattgtt agactacgct gaagctggag acaacattgg tgctttacta
     5881 cgtggtgttg cacgtgaaga catccaacgt ggacaagttt tagctaaacc aggtacaatc
     5941 acacctcata caaaattctc tgcagaagta tacgtgttga caaaagaaga aggtggacgt
     6001 catactccat tcttcactaa ctaccgtcca caattctact tccgtacaac tgacgtaaca
     6061 ggtgttgttg aattaccaga aggaactgaa atggttatgc ctggcgacaa cgtaacaatg
     6121 gaagttgaat taatccaccc aatcgctatc gaaaacggta ctaaattctc aatccgtgaa
     6181 ggcggacgta cagttggtgc cggtgtcgtt acagaaatca aagcttaatt cacttaagtt
     6241 ttaaagtaaa gcaacattta ttcggacgta atcgctcgga acgaaggtct taggatcttt
     6301 gttccgagct tttttattta ttgcaggatc aggaaaaaag acaggagtat tataaataga
     6361 agaaacacga aataaaagag tcagtatttt ctaaatgaaa ctttatgaaa acaaaatgtt
     6421 ttttacaaga aaaagccttg ctttgtgagt ttatatatat tataatgaca aaggtgcgtt
     6481 tactttagtg aattgcacag acgtaatcag aatgatttcg tcggctaaga aacgagaggt
     6541 tgcgacacgc ccggacgctt tgccacgaac gagcgtgacg gaaattttcg tggagctatg
     6601 tctacttttc aaaataggcg aaggagggaa caagatggca aaacaaaaaa ttcgtatccg
     6661 tttaaaagcg tatgaacacc gtattttaga tcaatcagcg gataaaatcg tggaaactgc
     6721 aaaaagaact ggagctagcg tgtctggtcc aattccatta ccaactgaac gcagtcttta
     6781 cacaatcatc cgtgcgactc ataaatacaa agattcacgc gaacaattcg aaatgcgtac
     6841 acacaaacgt cttatcgaca ttgtgaaccc aacaccaaaa actgttgatg ctttgatgaa
     6901 gctagactta ccatctggtg taaacatcga aatcaaatta taaaactaaa acaaaaataa
     6961 tggaggtgta ctcatgacca aaggaatctt agggaaaaaa gtgggaatga cacaaatctt
     7021 cactgaatct ggtgaattaa ttccagtaac tgttgtagaa gctactccaa acgtagtact
     7081 acaagtgaaa acaatggaaa cggatggcta cgaagctatt caagttggtt accaagatat
     7141 gcgtgaagtt ttatcaaaca aacctgcgaa aggtcatgtt gcaaaagcaa acacggctcc
     7201 taagcgcttc attcgtgaat tcaaaaatgt tgagctagga gaatatgaag taggaaaaga
     7261 aattacagta gatgttttcc aagcaggaga cattattgat gtaacaggta ctacgaaagg
     7321 taaaggattc caaggggtta tcaaacgcca cggacaaagc cgcggaccaa tggctcacgg
     7381 ttctcgttac catcgtcgtc ctgggtcaat gggtccagtt gcacctaacc gtgtatttaa
     7441 aaacaaacgt cttgctggcc gtatgggtgg caaccgcgta actatccaaa acttggaagt
     7501 tgtacgtgtc gatgcagaaa gaaatgttat cttgatcaaa ggtaatgttc ctggagctaa
     7561 aaaatcttta attactatca aatcagctgt gaaagctaaa taattgtagg aagaaaggag
     7621 gaactaagga atgccgaatg tagcattatt caaacaagat ggaagccaaa acggtgaaat
     7681 cacacttaac gaagaaatct tcggaattga acctaatgaa agtgttgttt acgatgcaat
     7741 cgtaatgcaa cgtgcgtcat taagacaagg aacacacgcg gttaaaaacc gtagcgctgt
     7801 tcgcggcggc ggacgtaaac catggcgtca aaaaggaaca ggtcgtgcac gtcaaggatc
     7861 tatccgctca ccacaatggc gtggaggtgg cgtagtcttt ggaccaacac cacgttctta
     7921 cagctacaaa cttcctaaaa aagttcgtcg tttagcaatg aaatctgtat tgtcagaaaa
     7981 agttgctgaa aacaacttgg tagcaatcga aggcttgaac ttcgacgcac caaaaacaaa
     8041 agaattcaaa caagttcttg ctaacttatc tatcgactct aaagtattgg ttgttctaga
     8101 aaaaggtaac gactttgctg ctttatcagc acgtaactta ccaaacgttt ctgtagtaac
     8161 ttctgataat gtgagtgtgc tagacgttgt atcaaataca aaagtgttag caacacaaac
     8221 tgctcttact caaattgagg aggtgcttgc ataatgaact tactagacgt aatcaaacgc
     8281 ccagtgatca ctgaaaaatc aatgcttgcc atggatgaca agaaatacac ttttgaagtg
     8341 gacactcgcg caaacaaaac tttagtaaaa caagcggtag aagctgcttt tgacgttaaa
     8401 gtcaaaaacg tgaacatcgt gaacgtacgt gcgaaattca aacgtatggg caaatatgca
     8461 ggatatacaa aaaaacgtcg caaagcgatc gttacattga ctgaagattc aaaagaaatc
     8521 caattattcg aagctgctga ataagcacta atagataact cattaaatta ggagggaaaa
     8581 acgtggcgat taaaaagtac aaacctacct caaatggtcg tcgtaacatg acaggttctg
     8641 attttgctga aatcacaaca tcaacacctg aaaaatcatt gttacaacca ttgaaaaacc
     8701 atgctggacg taacaacaac ggccgcatca ctgtacgtca tcaaggtggc ggacacaaac
     8761 gccaatatcg cgtgatcgac ttcaaacgta acaaagataa cgttgttgca actgttcaaa
     8821 cgatcgaata tgatccaaac cgttcagcta acatcgcgtt agtacactat gaagatggag
     8881 tgaaagctta catcttagca cctaaaggac tagaagtggg tatgaaactt gtttcaggtc
     8941 cagaagcaga tatcaaagtc ggaaatgctc ttccattaga aaacattcca gttggtactg
     9001 ttatccacaa cattgaaatg aaacctggta aaggtggaca attgatccgt tctgctggta
     9061 caagtgctca agtacttggt aaagaaggca aatacgtatt gatccgcttg aactctggtg
     9121 aagttcgtat gatcttagct gcatgccgtg ctacaatcgg ttctgtaggt aacgaacaac
     9181 acgaattaat caacatcggt aaagctggac gctctcgttg gatgcgtaaa cgcccaactg
     9241 tacgtggtag cgtaatgaac cctaatgatc acccacacgg tggtggtgaa ggtaaagctc
     9301 ctatcggacg taaagcacca gtttctcctt ggggtcaacc agctcttggt tacaaaactc
     9361 gtaacaaaaa agctaaatca gacaaactta ttgttcgtcg tcgcaaaaat aaataattac
     9421 tttgaccatg tgtcgcacat tttgagagga ggttcaccat gggtcgtagt ttaaagaaag
     9481 gaccttttgt cgatgagcat ttaatgaaaa aagttgaagc tcaagcaggg gttgaaaaga
     9541 aaaaagttat caaaacttgg tcacgccgtt caacagtttt cccaagtttt gttggatata
     9601 ccatcgcagt ttatgatgga cgtaaacatg taccagttta catccaagaa gacatggtag
     9661 gacacaaatt aggtgaattt gcacctacaa gaacttatcg tggacatgct gctgacgata
     9721 agaaaacgaa acgctaattt gaggggagga taaatccaaa tggcagaaca aatcacatca
     9781 gctaaagcaa ctgcaaaaac agttcgcact tcacctcgaa aagcccgttt agtaattgac
     9841 cttatcagag gtaaaagtgt cgcagatgca atttcaatct tgaaattcac accaaacaaa
     9901 tctgctggaa tcattgaaaa agtattgatg tcagcagttg cgaatgcaga aaataacttt
     9961 gacttagatg ttgaaaactt ggtagtaagc gaagcttttg ttaacgaagg acctacaatg
    10021 aaacgtttcc gtcctcgtgc aaaaggatca gcttctccaa tcaacaaacg tacaagtcat
    10081 atcacggtag tcgtatcaga aaaataagga gggataatca gtgggtcaaa aagtacatcc
    10141 aattggaatg cgtgtaggca tcatccgcga ctgggatgct aaatggtatg ctgaaaaaga
    10201 gtatgctgag ttcttacacg aagatttaag aatccgtaaa tttatttcaa ctaaacttgc
    10261 tgatgctgct gtatcaacag ttgaaatcga acgcgcaaca ggtcgcgtaa acatttcaat
    10321 tcacacagct aaaccaggta tggttattgg taaaggcggt tctgaagtcg aaagcctaag
    10381 aaaagaatta aacaaattaa ctggtaaaag aatccatatc aatatcgtgg aaatcaaaaa
    10441 accagatcta gatgcaaaat tagtaggtga aggaatcgca cgtcaattag aaaaccgtgt
    10501 tgctttccgt cgcgctcaaa aacaagccat ccaacgctca atgcgtgctg gcgctcaagg
    10561 gatcaaaact caagtatctg gtcgtctaaa cggagcagat atcgctcgtt cagaaggata
    10621 ctcagaagga actgttcctc ttcatacttt acgtgcggac attgattacg catgggaaga
    10681 agcagataca acatacggaa aactaggagt taaagtgtgg atctatcgtg gagaaattct
    10741 tccaactaaa aaaaacactg agaaaggagg gaaataatca tgttagtacc taaacgtgta
    10801 aaacaccgtc gtgaattccg cggaaaaatg cgcggggaag ctaaaggcgg aaaagaagta
    10861 gcattcggtg aatacggttt gcaagctgtt gattcacatt ggatcacaaa ccgccaaatc
    10921 gaagctgctc gtatcgcaat gactcgttac atgaaacgtg gtgggaaagt atggattaaa
    10981 attttccctc acaaatctta tactgccaaa gcaattgggg tacgtatggg ttctggtaaa
    11041 ggggcacctg aaggatgggt tgcaccagta aaacgtggta aaatcatgtt tgaaatcgca
    11101 ggcgttcctg aagaagtagc tcgtgaagcg ttacgtctag cttctcacaa attaccaatg
    11161 aaaactaaga tcgtaaaacg tgaggaaatg ggtggtgaat cgaatgaagg ttaaagaaat
    11221 cagagaatta accactgccg aaatgcttga tcaagaaaaa caattaaaag aagaattgtt
    11281 taatcttaga ttccaattag caacaggtca attagaaaac actgcacgta ttaaagaagt
    11341 acgtaaatcg attgcacgca tcaaaactgt gttgcgtgaa caagctaagt aattatggaa
    11401 ggaggccatt aagcgtatga ctgaaggaag aaatcaacgc aaagtttatc aaggtcgcgt
    11461 ggtttcagac aaaatggata aaacaattac cgttgctgtc gaaacaaaga aaaaccaccc
    11521 tatctatggc aaacgcatga actattctaa gaaatacaaa gtgcatgatg aaaacaacac
    11581 agcaaaagtt ggcgacatcg tgagaattat ggaaactcgt ccattatcag ctacaaaacg
    11641 tttccgtttg ttggaagtag tcgaagaagc agttattatc taataacacg agattttcct
    11701 atatagattg aatgcaaaat ctgaaaggag gatacacaac gtgatccaag cagaaagtcg
    11761 tttaaaagtc gctgataact caggcgcacg tgaaattttg acgatcaaag tccttggtgg
    11821 atctggtcgt aaaactgcta acatcggtga tgtgatcgtt gctacggtta aacaagcaac
    11881 gccaggtggg gttgtcaaaa aaggtgacgt cgttaaagcc gttatcgttc gaacaaaatc
    11941 aggagctcgt cgtacagacg gttcatatat taaatttgat gaaaatgctg cagtgattat
    12001 tcgtgatgat aaaagccctc gtggaacacg tatctttggg ccagttgcac gtgaactacg
    12061 tgaaaacaac ttcatgaaga tcgtttcact agcaccagaa gttttataat cttgagacac
    12121 ttatcaaagg aggtgcgaaa cagttatgtt tgttaaaaaa ggcgataaag ttaaagttat
    12181 cactggaaaa gacaaaaaca aagaaggcgt tgtactagca gcgttcccga aaaaagataa
    12241 agttattgtc gaaggtgtaa atgtcgttaa aaaacaccaa aaaccttctc aagctgctcc
    12301 tcaaggtgga attgttgaga tggaagcgcc aattcatgtt tctaacgtga tggtggttga
    12361 ctctactggt gtagctggcc gagttggcta caaagaagta gacggcaaaa aagtccgtgt
    12421 ttctaaaaaa accggtgaag ttttagataa ataaaagttt aaggaaggag ggtcttactg
    12481 aatgaaccgc ctaaaagaaa aatatcttaa agaagtaact ccatcattga tggaaaaatt
    12541 taactatagc tctgttatgc aaacacctaa agttgaaaaa atcgtcatca acatgggtgt
    12601 tggtgatgcg gtatcaaacg ctaaaaactt agataaagca gttgaagaat taactttgat
    12661 cactggtcaa aaaccaatga ttacaaaagc taaaaaatca atcgctggat tccgtttacg
    12721 tgaaggaatg ccaattggtg caaaagttac attgcgcgga gaaagaatgt acgaattctt
    12781 agacaaattg gtttctgttt cactaccacg tgtacgtgac ttccatggtg taagtaaaaa
    12841 agcctttgac ggtcgtggaa actatacttt aggtattaaa gaacaattga tcttcccaga
    12901 agtagattat gatttagtag ataaagtacg tggtatggac atcgttattg taacaacagc
    12961 aaactctgat gaagaatctc gtgagttgtt gacacaatta ggcatgccat tccaaaaata
    13021 attaaaggag gcgaactacg tggctaaaaa atcaatgatt gctaaaaaca aacgtcctgc
    13081 aaaattttca acacaagctt atactcgttg cgaacgttgc ggacgtccac attcagttta
    13141 tcgtaagttc catctttgcc gtatttgctt ccgcgaactt gcctataaag gtcaaattcc
    13201 cggcgtgaag aaagctagct ggtaaaaagt aaattcgcat aagaaggagg taaaagatca
    13261 atggtcatga cagatccaat tgcagatttt ctaactcgta tccgtaacgc aaacatggtt
    13321 aaacatgagt ctttagaagt acctgcatca aaaattaaac gtgacatcgc tgaaatcttg
    13381 aaacgtgaag gtttcgttcg tgatgttgaa tacatcgaag atgacaaaca aggcgtgatc
    13441 cgtgttttcc taaaatttgg taaaaacggc gaacgtgtta tcacaaactt aaaacgtatc
    13501 tctaaaccag gtttgcgtgc ttatgtcaaa gctgacgaag taccaaaagt attgaacggt
    13561 ttaggtatcg caatcatttc gacttctgaa ggtgttgtca ctgataaaga agctcgtgaa
    13621 aaaaatatcg gcggcgaagt tatcgcttac gtatggtaat caagtagaat ctacaaggag
    13681 gtgtctttaa gtgagccgta tcggaaataa agtcgttgtt atccctgaag gagtaacagt
    13741 tactcaagac ggaaacaacg ttacagttaa aggaccaaaa ggtgaattga ctcgtacttt
    13801 ttcagcagat atcaaaatga atatcgaagg aaacgaagta actttcactc gtccaaacga
    13861 cagtaaagaa atgaaaacaa ttcatggaac aactcgtgcg aacttcaaca acatggttgt
    13921 aggtgtcagc gaaggtttcc aaaaagcgtt agaactaatc ggggttgggt accgtgcaca
    13981 attacaagga tcaaaacttg tattgaacgt tggttactca catccagtag aaatcacacc
    14041 accagctgga gtaactgttg aagtaccagc taacacacaa gtaattgtta aaggtgcgaa
    14101 caaagaagaa gttggcgaat tagctgcaaa cattcgtgga actcgtcctc cagaacctta
    14161 taaaggtaaa ggtattcgtt atgttggcga atatgtacgc cgtaaagaag gtaaaactgg
    14221 taaataatcg tttagaaaaa ttgcatagaa gccagcagca ggaaaaaggc atttggctga
    14281 agtttacctt caaaaaaata catttttact tgtgccgcag cttctatttt tcgaaacgta
    14341 tttactgctt gaaatagtag tacaataaaa ataaagaggt gacaattgtg attacaaaac
    14401 cagataagaa caaaacacgt caaaagagac atcgtcgtgt acgtaacaat atctctggta
    14461 ctgctgagcg cccacgcttg aacgtttttc gttctaacaa aaacatctac gctcaaatta
    14521 ttgatgacgt agcgggtgta acgctagcaa gtgcctctac cttggataaa gaaatttcag
    14581 gtggaacaaa aacagaagca gcacaagctg tcggtaaact agttgctgaa cgtgcagctg
    14641 aaaaaggcat taaagtagta gtctttgacc gtggtggata cctttaccat ggccgtgtgc
    14701 aagctttagc tgaagctgct cgcgaaaatg gactagaatt ttagaagaag gaggaatacc
    14761 attcatggtt tatatcgatc caaaacattt ggaattagaa gaccgcgttg ttgcaattaa
    14821 ccgtgtaaca aaagttgtta aaggtggacg tcgtctacgt tttgctgctt tagttgttgt
    14881 cggtgacaaa aacggacacg taggatttgg tacaggtaaa gctcaagaag ttcctgaagc
    14941 aatccgtaaa gcaattgaag atgcgaagaa aaacttagtt gaagtaccta tggttggttc
    15001 aacaatccca cacgaagtaa tcggtgcttt tagtggtggt agaatcctaa tgaaacctgc
    15061 tgtagaaggt tctggggttg ctgctggtgg accagttcgt gccgtattag aattagctgg
    15121 ggtagcagat atcacttcta aatctttagg ctcaaataca ccaatcaacg ttgttcgcgc
    15181 aacagttgaa ggtttgaaac aattgaaacg tgcagaagaa gttgcagaac ttcgcggcaa
    15241 atcagttgaa gaattaatcg gataaggagg acaacaataa tggctgaatt aaaagttact
    15301 ttaaaacgca gtattatcgg acgtcctcaa aaccaacgcg atacagttaa agcgttaggt
    15361 cttacaaaga ttaacagttc agtggttaag ccttctaatg aagcaattaa aggcatgatc
    15421 aatactgttt ctcacctagt ggacgttgaa gaaatttaat ttagaaaaat cataactaga
    15481 acattaagga ggtgccaaac ctatgaaact tcatgaatta aaacctgctg aaggttcacg
    15541 ccaagtacgt aaccgtgttg gtcgtggtac ttcatctggt aacggaaaaa ctgccggacg
    15601 cggacaaaaa ggacaaaaag ctcgttcagg cggcggtgtg cgtttaggat ttgaaggggg
    15661 acaaacacca ttgttccgtc gtttaccaaa acgaggattc acaaacgtga accgtaaaga
    15721 ctatgcagtc attaatcttg atgtattgaa ccgctttgaa gacggagctg aagtaactcc
    15781 tgttgcttta gttgaagctg gaatcgtgaa aaacgaaaaa gctggaatca aagtattagc
    15841 taatggggaa ctaaacaaga aattaactgt gaaagcagca aaattctcta aagcagctca
    15901 agaagcaatt gaagcggctg gtggatcaat cgaggtgatc taatgtttag actattaaaa
    15961 gatgctttta aagtaaaaga cattagatcg aaaatcctat ttactgtatt tgtgttgttt
    16021 gtatttcgcc taggtgcaca tattactgta ccaggcgtaa atgctgcttc attgcaaaac
    16081 ctttcttctt tgccattttt caacatgttg aacttggtaa gtggtagtgc gatgcaaaac
    16141 ttttccattt tctcaatggg ggtttcacca tacattactg cttctatcgt cattcagctt
    16201 cttcaaatgg acatcgtgcc tcgatttgtt gaatggtcga aacaagggga agttggtcgt
    16261 aaaaaactga atcaagcgac tcgatatctg acattagtat tggcatttat ccaatctgtc
    16321 ggtatcactg ctggattcaa tcaatacgct caattaggtt tcgtgaataa tcctaacgta
    16381 gcaacttacg taacgatcgg tttgattcta acagccggta cgatgtttgt tacttggcta
    16441 ggagaacaga tcacagaaaa aggtatcgga aatggcgtat caatgatcat ttttgcaggt
    16501 atcatttcta gattgcctga aagtatcaga gaaatttatg aagattactt tataaatatt
    16561 gatccttcag acatatggaa atctgctatt tttgtggcca ttttactagt agcggtcttg
    16621 ttgatcgtga cattcgtaac atttttccaa caagctgaac gcaagatccc gatccaatat
    16681 acgaaacgcg tagctggcgc gcctacaagc agctatctgc cgttgaaagt aaatgcagct
    16741 ggagttattc cagttatctt tgctagttcg tttattgcta cgccaaatgc tgttttacaa
    16801 gcattgagcg gtagattcgg ttctgaaaac tggtacaaag tgatgatgga gatctttaac
    16861 tataatacag cacctggtgc tacgatttat acgattctga tcgttgcctt cactttcttc
    16921 tacgcctttg ttcaagtaaa ccctgagaaa ttagcggaaa acttgcaaaa gcaaggaagt
    16981 tatataccaa gcgtacgccc tggtaagggg actgaagagt atgtctcaag attactgatg
    17041 cgtttaagta cagttggtgc agtcttcctt ggtttagtgg cattgcttcc aatcattgct
    17101 caaatggttt gggatcttcc acaatcaatc ggattaggcg gtacaagctt actgatcgtt
    17161 atcggtgtag ctttagaaac tgcgaaacag ttagaaggct taatgctgaa acgtaaatat
    17221 gttggattca ttgagtaaga aagcgtgttg aggtttcccc tcaacacacg ttctcacaca
    17281 tttattagga gggaaaacaa tgaacctcat tttaatgggg ctgccaggcg caggtaaagg
    17341 aacacaagct gaaaaaatca ttgatgctta tggtattccg cacatctcaa caggagatat
    17401 gttccgcgca gcgatgcaaa acgaaacagc tcttggcctg gaagcaaagt cttatatgga
    17461 taaaggtgca ttagttcctg atgaagtaac aaatggaatc gtgaaagagc gactagctga
    17521 accagataca gagaaaggct tcttattaga tggctttcca cgtacgctag atcaagcaaa
    17581 agctctggac gcaatgctaa aagatttgaa taaaaaaatt gatgctgtca tcgatatcca
    17641 tgttggtgaa gaaatcttgg tcgaacgtct agccggccga tttatctgca gcaattgtgg
    17701 agcaacttac cataaaattt tcaaccctac aaaagttgaa gacacatgtg atcgttgcgg
    17761 tgggcatgaa ttctatcaaa gagaagatga taaacctgag acggttaaaa atcgtctggc
    17821 tatcaacatc aaaaatagtg aaccaatctt ggcttattat aaagaacaag gtttgctaaa
    17881 cactattgat ggtgctcgtg aaatcgatgc tgtatttgca gatgtacaaa aaatcattga
    17941 aaaatagcac gattgcccgt agccgacttg cattatgcag ttactcttgt caagttcaat
    18001 aaattatgat agaatatgtc agtccgactt ctagagaatc ctctagatga tccattttga
    18061 gaattttgag gtgggaactg cagtttccgc cattttatcg tgtgaaaatg cgaaacaagt
    18121 acaaggaggt actgtgcgtg gcaaaagaag atatgattga agtcgaaggt acagtcgtcg
    18181 aaactttgcc gaatgcaatg tttaaagttg aactagaaaa cggacaccaa gttcttgcta
    18241 ctgtttcagg taaaattcgt atgcattaca tccgtatctt acctggtgac aaagtaacgg
    18301 ttgaattgtc tccatacgat cttaaccgtg gccgtattac ttatcgcttt aaataattgt
    18361 actccgtaaa actacaggag gtattatcat gaaagtaaga ccatcagtaa aaccaatgtg
    18421 cgaacattgt aaagtaattc gtcgtaaagg acgcgttatg gtgatttgcc cagcaaatcc
    18481 aaaacataaa caacgtcaag gataattgga ggtgctataa atatggctcg tattgcagga
    18541 gtagatattc ctcgtgataa acgtgtagta gtttcactta cttatatcta tggtattggt
    18601 aacactactg ctaaaaagat cttagctgat gctggtgtat ctgaagatgt tcgcgttcgt
    18661 gaattaacga atgaacaaac agatgctatc cgtgcagaag tagataaatt aaaagttgaa
    18721 ggggatcttc gtcgtgaagt gaacttgaac atcaaacgtt tgatggaaat cggttcttac
    18781 cgtggaatcc gtcatcgccg tggattgcct gttcgtggac aaaacacgaa aaacaatgca
    18841 cgtactcgta aaggcccagc tcgcgctatc gctggcaaga aaaaataatt cttaagtgaa
    18901 ggaggttaaa acttcatggc agcaaaaaaa gtgaatcgta aacgccgtgt gaagaagaat
    18961 atagaagcag gtattgcaca tatccattct acattcaata acactatcat catgatcact
    19021 gatactcacg gaaatgcatt agcgtggtca tcagctggtt cattaggttt caaaggaagc
    19081 aaaaaatcaa ctccttttgc cgctcaaatg gcagcagaaa ctgctacaaa agcagcaatg
    19141 gaacacggat taaagactgt tgaagtaaca gttaaaggac ctggttctgg acgtgaagca
    19201 gcaattcgtt cattacaagc tacaggttta gaagtgactg caattcgtga cgtgactcca
    19261 gttcctcata atggtgcccg ccctccaaaa cgccgtcgtg tttaatgagt gccgctcatt
    19321 ttgagtttta tcagtaacgt cattgaacaa gacacttttc gttttgaaag gggtaaagat
    19381 aagaatgatt gagttcgaaa aaccaagaat cgcaaaaatt gatgaagaaa aagattatgg
    19441 caagttcatc gttgaacctc ttgaaagagg gtatgggact actttaggga attccctacg
    19501 tcgtatttta ttatcttctt tgccaggtgc tgccatcact aatattcaaa tcgatggtgt
    19561 actgcatgaa ttctctacca tcaaaggtgt tagagaagac gtcactcaaa tcatcttgaa
    19621 cattaaaggc ttagcgctga aaatgtatgg ccaagaagaa aaaacccttg aaatcgatat
    19681 taccggacct gctacagtaa ctgctggcga tattatcgtt gatagtgatg tagaaattct
    19741 taacaaagat atgtacatct gtagtgtctc tgaaggagct acgttccatg ctcgcttaac
    19801 agtgaaacct ggacgtggtt atgttcaagc agatgaaaat aaaaaagaag atatgccaat
    19861 tggcgttctt ccagtcgatt caatctacac acctgttcgt cgtgtgaact atcaagttga
    19921 gaacacacgt gttggacacc gtgaagattt tgataaattg acgatggaga tttggacaga
    19981 tggttcaatt gaaccgttgg aagcaatgag tttgtctgcg aaaatcatga ctgaacattt
    20041 ggatattttt gtgaacttaa ctgatgaagc aaaaaatgct gaaatcatgg tcgaaaaaga
    20101 agaaacacaa aaagaaaaaa tgttggaaat gacgatcgaa gagttagact tgtctgttcg
    20161 ctcttacaat tgtttgaaac gtgcaggaat caatactgta caagaactta caaataaatc
    20221 tgagcctgaa atgatcaaag tccgtaactt aggacgtaaa tcattagaag aagttaaagc
    20281 aaaattgcac gacttaggtt taggtttacg taaagaagat taaaaccttt tacgaaggag
    20341 ggaaaccaac gtgagttatc gtaaactagg acgcacatct agccaacgta aagcgatgtt
    20401 gcgtgattta acaactgatt tattaatcaa cgaacgtatt gtgactactg aagctcgtgc
    20461 gaaagaagtt cgctcaactg cagaaaaaat gatcacttta ggtaaacgcg gagatttgca
    20521 tgcacgtcgt caagctgcgg ctttcgtacg taatgaagtt gccagcgtgc gtgaagaaaa
    20581 tgaggacatc gtcattgaat cagctttaca aaaactgttc aacgatattg cacctcgtta
    20641 cgcagaacgt caaggcggat acacacgcat tttgaagaca gaaccaagac gcggtgatgg
    20701 tgcaccaatg gttgtcttag aacttgtcta aaatcacact aataacatca ctttatagat
    20761 gattctttta gagtgttatg atgttggaag atatttttcc gagtctagct cagcgctgct
    20821 cctcaagcga atatcgcttg gggagtaagc actcatcata aagtgttttt ttataccttc
    20881 aattacctgt catgacagat atgtttgaag gcataaaaaa acattttaag cgagaaataa
    20941 ttgaaaattt tgtctttttt tgatagtgtt agtaggaact ttaggatgaa gaaggagtaa
    21001 tcatggagcc aattattgaa ttagaaaaga taaattataa ataccagcca gatgatcttc
    21061 gccccgcatt gaaagatgtc tcctttacaa ttgataaagg tgagtggatc gctattattg
    21121 gacacaatgg ttcaggaaaa tcgacacttg ccaaaacgat caatggattg cttctgccag
    21181 aatcagggat cgtgaaagtg ggaaatcaaa tattggatga agaaaatatt tggacgatcc
    21241 gacagatggt tggaatggtt tttcaaaatc cagacaatca gtttgttggt tcgacagtag
    21301 aagatgacgt tgcttttggt cttgaaaatc aagggattcc cagagaagaa atgctagtgc
    21361 gtgtgaaaga tgcacttgag aaagttagaa tggctgagtt tgcttcacgc gagcctgctc
    21421 gtttatcagg agggcaaaaa caacgtgttg ccattgccgg cgtggttgcc ttacgacctg
    21481 atatcattat tttagatgaa gcaaccagta tgctagatcc agaaggtcgt gaagaagtga
    21541 tctctacgat caagaagatc aaagaagaaa gtcaattgac cgttatatct atcactcatg
    21601 atattgatga agcagctaat gccaatcgga tactagtgat gagacaaggc gaacttgtcc
    21661 gtgaaggtac accaaaagaa attttttctg ctggtcctga actgatcgac ttaggtctag
    21721 atctaccatt tcctgaaaaa ctgaagagcg cactgaaaga acgtggggtt gatgtgccca
    21781 gtgaatatat gacagaagaa aggatggtgg attggttatg gacatccgtt ttgaacaagt
    21841 agacttcact tatcagccga atacaccatt tgaacaaaga gccttatttg acatcaatat
    21901 gacgatcaaa gaaaacagtt atactgcatt agtagggcat accggaagcg ggaaatcaac
    21961 cttacttcag catttgaatg cgcttgttaa gccaacaagc ggtacagtcc atattggaga
    22021 acgagatatt cagccggata cggataataa gaatttaaag cccatccgaa aaaaagttgg
    22081 catcgtcttt cagtttccag aagcacagct attcgaagaa acggtagcaa aagacattgc
    22141 tttcggtcct aaaaactttg gtgtcagcga agaagaagca ctagtcctag caaaagaaac
    22201 attagaacaa gttgggctgg atgaaagcta tttggaacgt tcgccatttg aactttcagg
    22261 agggcaaatg cgtagagtag caatcgctgg tgtgcttgcc atgaggccgg aagtacttgt
    22321 attggatgaa ccaacggcag gacttgatcc ccagggcaga aaagaaatga tggagatgtt
    22381 ttggcgtctt cataaggaac agcagatcac tattgtatta gttacgcatt taatggatga
    22441 tgtagccaat tttgcagatt atgtctatgt gttggaaaag ggacgaatcg ttaatagcgg
    22501 ggagccgcaa gaggtctttc aaaacattga atggctaaaa gaaaaacaac taggcgtacc
    22561 tactgccacc gagtttgcag aagaattaat ggctaaaggg atgaactttg ctaccttgcc
    22621 tttgacagct gaagaattag cagacgctat cgtccattat gctggaggaa atgcccatga
    22681 tgaataaatt gatatttggt cgttatatgc ctggagattc cttgatccat cgattggatc
    22741 cccgagctaa attattagcc agtttttatt ttatcggaat cattttttta gcaaataatt
    22801 gggaaacgta ccttttgttg gcatttttca cattactttc tgtcttcttg tcaaaagtag
    22861 atttgaaatt ttttatccga ggcattcgcc cattgatctg gctaatcctc ttcactgtag
    22921 ctttgcaggt cttgtttaca agtggcggag aaacttattg gagttggggt gttttccata
    22981 tcactgaatt tggtgtgatg aacggcctct ttattttctg tcgattcgtg ttgatcattt
    23041 ttatgtcgac tctactcacg cttactacac cgcctttgga attatcggat gcgattgagt
    23101 acttgcttcg tccattgaaa gccgtacggt tcccagtcca cgaaatttca ttgatgctgt
    23161 cgattgctct tcgttttgtg cctacattga tggacgaaac agaaaagatc atgaacgctc
    23221 agcgcgctcg cggtgttgat tttggtgaag gaaacctagt tcagaaaatg aaagcagtca
    23281 ttcctttgct gattccttta tttgtcagca gcttcaaccg tgcggaagat cttgcgactg
    23341 ctatggaagc aagaggctac aaaggtgggg aaggaagaac gaaatatcgt gtattgcatt
    23401 ggcataatag agacacgatg gttatcattg cttttgtatt attaactgtg ctactgatct
    23461 ttttaagagg ataaacgttc agtgggccgc tatctattct tttcttgctg atctgtttgc
    23521 aagaaaggat gcaagcagtg tatgacaaga aatattaggg tctgtggcag actaaggtca
    23581 caggcctctt tcttttatct gaaaagaaag aacgaaaaaa ttttatagaa aaatcattat
    23641 tccagataac cttttaggaa caaaggagag aaaaacatgg tacgttacaa agcaatcatt
    23701 gcgtacgacg gaacaaattt taatggattc caaaaacagc caaatgggcg tactgttcaa
    23761 gaagaagtag aaaaaacatt acaaaaaatg gcaaatggaa aagaaatcac ggtctttggt
    23821 tcgggaagga cagatgccgg agtacatgcg atcgggcaag taatccattt tgattatcca
    23881 gaggagcgtc cgttagaacg aatgcgtttc gcgctagata cccagtcacc agaggatatt
    23941 gctgtaagac aagtagaaat tgtttcagaa gacttccacg caagatattt ggtcaaagaa
    24001 aagacgtatc aatttcgagt ggatataggg aaaccacgca gtccttttcg acgccattat
    24061 gcaagttatt ttccttaccc acttgatttg gaaaaaattc agcgggcgct tcctgattta
    24121 ttagggactc acgatttcac ctctttttgt gcatcaggaa gctcgataga ggataaaata
    24181 cgtacgatct acgaggctaa gatggaggta aatgaaacaa aagacgaatt gttgtttaca
    24241 tttaggggaa atggcttctt gtataagatg atacggatct tagtaggaac gcttttgaaa
    24301 attggcaatg gccgattgcc tgaagatagt atcccagata ttattgcgaa aaaagatcgt
    24361 aatgcagcag gacctacagc acaccctgaa ggactttatt tgtatgaagt gaaatatgaa
    24421 taagaggtta tgatagaagt ggtcagcttc aagaaataag aaggtattta cgaaaattac
    24481 ttctcaaaat tttgcaaaat ttcggcttat tttcgaagaa gctacttctg gaacaccgtt
    24541 taaggaagag gtcgtgaaat cagcgttttg acctgagtat tagagaaaca aacgggaaaa
    24601 tagctcctca tattttgccg tttgttgagc taataccgaa ggtcagctga ttgaacaccg
    24661 tttaagaaag aggtcgtgag cctgtcattt aactctgagt cacaaagagc aatttcaaaa
    24721 aacagcttct catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc
    24781 atctttttgt tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc
    24841 cttggtgcgg acagtctgaa caggttccat cgtttcttta ttttctacgt cttcttctgt
    24901 gtgtgtttcg tggttgttct tctattgctg gatcaatcgt gccataaaag gggcgattgc
    24961 ggtcaaggta ccagacataa agaataaaca atgcaataca taggacaaaa aggattgcac
    25021 ctatcgtaaa tccttcaggc aagtaactga aagtgacagt atgtttacct gctggaactt
    25081 ttatcatcaa gaatgcgtct ttgaaattgc tgaccttgac tggtttccca tcaattttag
    25141 ctttccatcc tttgtcataa ggaatagttg tcaccaacat ggaatcttca gcggtattta
    25201 cagtcccaga agcttttctg ccagtggctt ccatttcgac acctttttct ttgatctgat
    25261 tcattgcggc ttgataggct acaacatcta gaccaacgac tttaggctcc atgaaactta
    25321 tttctttcgt cccataaaaa cttgcagtaa atgtcactgt tgtctcttga ggataatagc
    25381 caagatcata gtattgacca gaaatgttga tttgcgtttt tcgcgatgta ccattgacag
    25441 tgatcgtcgc actagaactt tctaattgcg caaaattggt tgggaacaaa cttaagtaag
    25501 cttgtgtatt tgcaggcaca tggacttccc aagtgagctc ttttggctgg ttatctgctg
    25561 tttctgagta agtgacgcca gtcgttgtct ttgtgatcgt cgtattcaac tgattcttca
    25621 aagtaggtgt atagaatgta aaatactgtt catttagacc agacaatgta ttgatcaagt
    25681 ttgtctgact ggtcaaatta tctgtcactg gctgctcaac atcattaacg gacaacggtg
    25741 cagtaaatgc tagtggcaat gcattgacat tctgatacag tgtatagtcg ccgctttgac
    25801 cagcttggcg gaagccatat ttactgaacg tgctttcgtt tttagaaatg ttatatttga
    25861 ttcctgtaaa cccatccatc agcaaagtat tattgttata acggatattc aaatttgtcc
    25921 ctcttgaacg gaaacctaat ttatccaggt aagaggaaga attacgattt cttatagaag
    25981 aaaacaaact gataccactg taaccatagt tgatcgaatc gtttgcagat actggatcca
    26041 gattttccaa gcggtaaaac gagtcggaat ctttttttgt ttcatttaca agagctttca
    26101 agtcaggata aggatcagta tataaactgc gggaagcata attccaatca tcaagaatgc
    26161 catggatcat actgttcgta ttgaccagtg cttcagcaga catgatcaat aataacaata
    26221 tactcagatg attgaatgaa agttttttat gctgataaaa tcccacagca aaagcataaa
    26281 tccctaagaa aaccactgtc aatacaaagg aagtcatcgt cacataggtg tagcttcctt
    26341 caggtttgat gccccatgcc accgcaaaga gagcagctac gaccaaaatg attcctaaca
    26401 acagcccacg atcgtcttgt tctatctttt cccatccttt tcctgcaagc aggagcacta
    26461 agaaagagaa cagataggca taacggaata aaaacatatt cggtgcatgc ataccatgcc
    26521 agaacaaatt caatggaaca agataaaaac ttgcgataag tatggcgaaa agactgccgt
    26581 acaaaaattt atttttcaac ggtactttcc gactggcaaa ataaaacaga cagaggacta
    26641 atggtagcag acctgcgtaa acgaacggaa tcgatccgta ttttgtcgtg tcataaacac
    26701 caatcatatt tttcatgatt agatccagat aagaagtcgc ttctgttttc aacgtagtga
    26761 tctgactcag tgcctcgcca tttgaccgaa gatccagcac tgctggcaat acaatgatca
    26821 ttgaagcgcc gcctgccagt aaagaagtga taccataagg aacaatcgtt tttttatatt
    26881 ctgaccagtt tgtcaataga cgggcgataa aatataagaa agaaaatacg ccaatcataa
    26941 aacccatata aaaactggat aaaaacaaga gtaaataact gataaataaa agtttcggcc
    27001 gtttaagatc cataacacga tgaatcccca aaatcactaa tggaagataa aaaaatgcat
    27061 ccagccacat gatgatctcc gaatgtgcag tgataaatga gatcaatgcg taactgacgc
    27121 taagtgcaac atgcccccag cgaggaatct tgaacgtacg tgcaagaaac caaaaagcca
    27181 atccggcaca gccgacctta agcaaagtca gaacatacag tgcatctggc atcatctggt
    27241 ttggaaaaaa gaacaccagt ggcgtgaaga tcccgcctag atagtaagaa attaaagata
    27301 aataattcaa tcctagagaa gcattccatg tataaaaaat actttgcttt ccaagaagaa
    27361 catttcggaa gctggcatga aaattagaaa actgtgaaaa ggcatcactt gccaaaatac
    27421 ttctgctgct tccaggatag attccgatac ttagataaac aagtgctaaa atcaaaaacg
    27481 gaatcaggaa actagctgct gcgtagcgtc cgttttctct aaagaatgac tttaaatttt
    27541 ttttcatatt tattttccac caaatttcta tgaagttgta ttcagtttat catatccttg
    27601 tttttctctg cttaaaaaga gtctagtttt cacaaaaaaa taaaatttag aataaataac
    27661 ttcataattt gttcgtataa caaaaataaa cgcaaaaaaa gggtaggaat caaaagtccc
    27721 acccttaaaa atttttatta aataaaaaac cgttcactat ctgaacggtc caagtatcat
    27781 tcaattaaac gcgttcaact tttcctgatt tcaaagcacg agttgacacc caaacttttt
    27841 taggttttcc gtcgaccata acgcgaactt tttgtaagtt aggtttaaca gtacgttttg
    27901 ttgagttcat agcgtgtgaa cggttgtttc cactttttgt cttgcgacct gtaaagtaac
    27961 aaacttttgc catggtaatt tcctcctttg ccttgatttg gagcaataga ataattcagc
    28021 tcataccaga ctaacatatc atatagaatg ggaatttgca agtacatttt catagataca
    28081 attgacaatt gagaagaata attgtaaatt aaacaaggtt atacctgaaa ttttgcaagg
    28141 tttttgagta ctttgggtaa ctgcctttta tttcaagttg cgctatgata aaatatgata
    28201 gaagaaaaat gggagttttt tacccgttaa ggaggctcat tcatggctgt aaaaattcaa
    28261 acgtcagctg gaaccattga aattaccaat gatgtaattg caacagttgt tggtggcgcc
    28321 gcgacagatg tgttcggtgt tgtaggaatg gccagcaaaa atcaaattaa agataatatt
    28381 actgagattt tgcgtaaaga aaattactca agaggagtag ttgtccgcca agaagataat
    28441 ggtattgctg tagatgttta tacgattatc agctatggta cgaaaatctc tgaagtttcc
    28501 cgcaacgtcc aagaaaaagt gaaatacaat ctagaggcat tattaggcgt aactgccaat
    28561 tcagttaatg tctttgtaca aggtgttcgt gtactgccag actaggcagg agactggctg
    28621 gtaactcagc agtcgatctg aaggaggatt atctaggtga gtgtaacaga aataagtgca
    28681 agccagttcc aggaaatggt ccaggcaggt gcgaatcgtc tgcaagtaaa tgcagaatac
    28741 gtcaattcat taaatgtatt ccctgtgcca gatggcgata cgggaacaaa tatgaatcta
    28801 tctatgacta gtggagctaa ggcagtagta gattcaacct cagaaaaagt aggagaatta
    28861 gcagcaatgc tttcaaaagg attgctgatg ggtgcgcgcg gaaattccgg cgttattttg
    28921 tctcaattgt ttcgtggatt ttctaagcaa attccagatg ttgtctcatt aaatgcttct
    28981 gatcttgctg cagccttcac tcatggagtt gaaactgcgt ataaagcagt aatgaaacca
    29041 gtagaaggaa cgattttgac agtagctaga gaagcagcga aagctggaga aaagaaagca
    29101 aaaagtactg atgatgtcgt tgaagtaatg acagctgttg taaaaggagc aaagcgtgct
    29161 ttagctaaaa ctccagactt gcttccagtc ctaaaagaag tcggtgtcgt agacagtgga
    29221 gggcaaggac tgctgtttgt ttatgagggc tttttaagtg cattgaatgg agaattccaa
    29281 gcggatgaaa catatgaacc ttctccagca gaaatggatg atatggtcaa tgcagaacat
    29341 catcgcagtg tccaaggtca aatggcgaca gaagatatcc attttggtta ctgtacagaa
    29401 atcatggtaa aaatcggaga aggacctaca gtcgatagta cattcgatta cgaagaattc
    29461 cgtaactatt tagatggtat aggagattct ttacttgtgg tcaatgatga cgagatcatc
    29521 aaagtccacg tgcatacaga aaacccagga gaagtcttga attatggaca aaaattcggt
    29581 tcattagtca aaatcaaagt cgacaacatg cgcttgcagc atgagacgat tttggaacac
    29641 gatgaagaag tgaacgagtt tgcgaaaaaa gaaataccac gtatcccgta tggtatcgta
    29701 gcgatcgctg ctggtaaagg cgtccaagag ctgtttgaaa gtttaggcgc taattatgtt
    29761 atcagtggtg gacaaacaat gaatccaagt acggaagaca ttgttaaagc gattcaagaa
    29821 gtaaacgcag ataaagtgat tgtcttgcca aacaataaga acatcttcat ggcagctgat
    29881 caagcagcag aagtagcaga tatcccagta gcagttgttc cttcaagaac gatttcccaa
    29941 ggattgacag ctatgctttc attcaatgat caagcttctt tagaagaaaa caaagaaacg
    30001 atgacagaaa tgttgtctag cgttgtgagc ggtcaagtca ctcacgcgat cagagatacc
    30061 tcaattgacg gtgtagagat caaagaagga gactttttgg gcatgatcga tggaaaaatc
    30121 ctgatctcta acccagatat cacagcaaca gcgttaagta cactagaaca aatgatcaat
    30181 gaggacacag agatcgtaac gatcttggca ggtgatgaag gaacagttga acaagcaaat
    30241 gaatttgctg agaaactaac agaaaaacat cctgatttgg aaatcgagat ccaccaagga
    30301 gatcagcctg tctatcctta tctattttct gctgaataat ttctgtgtca gaatatcttt
    30361 ctaacacagt attcattcat aaaaggcctt cggttagtga tcaggtatga tcgctgacca
    30421 agtccttttt ttgttaaagg agggaggaaa aatttatgcg ttctttagat gatccaatca
    30481 ctatgctggc aggagtcgga gaaaaaagag cagctagtct tgccagcttg ggcatccaaa
    30541 cgattgaaga cttactgact tattatcctt ttcgctacga agatattcag gaaagaaatc
    30601 taaacgagat ccaggatcaa gaaaaggtta ctttgaaagg aatcgtagtc tcgcctcctg
    30661 tgatgaatcg atttggttat aaaaaaagcc gattgcaatt tcgtatgatg caagaacatg
    30721 atgtgttcaa cgtttctttt tttaatcaac cttatctaaa agaaaaagtc attttatcgg
    30781 aggaaatcgc cgtatacggt aaatgggatg caaagcgtaa agccttgaac gggatgaaga
    30841 ttttaggttc tcaaacaatg gatgactttt cgccgatata tcacgtcaac aaatcaattc
    30901 gtcaaacgac attagttgat ctaatcaaaa aagggtttca agaatacggc acattgattg
    30961 aagaaaatct gccaaacaac cttgtggaga aatatcgact gcttgaccga gcttctgctg
    31021 taagaagtat gcattttcca aaagaccacg aagaaaacca tcaagccaaa cgacgtgtcg
    31081 tttttgaaga gttcttttta tttcaaatgc gtcttcaagg attgaaaaaa gcagaaaaag
    31141 cagaaacgaa tggtttggag atcctttatg atgtccaaaa attgaaacaa tttactcaaa
    31201 agctaccttt tgaactgaca aatgcacaaa aacgtgtaac gaatgaaatc tgtcgggatc
    31261 ttcgcagtcc gcagcatatg cagcgacttt tgcagggaga tgtaggtagc ggaaaaacag
    31321 tggttgccgc gattgcgtta tacgctaccg ttacagcagg tttccaaggt gcgttgatgg
    31381 tgcctacaga aatcttggca caacaacata tggaaagctt gcaacagctg tttgatccca
    31441 atgaagtaac catcgcattg attacggggt caacgaaagc aaaagaacga cgtgagctcc
    31501 ttgaaaaact agagcaaggg gaaattaacg tcgtgatcgg cacacatgca ttgatccaag
    31561 atggagtcga atttcagaat ttaggtctag ttattacgga tgagcagcac cgttttggcg
    31621 tgaaccagcg gaaagtactt cgtgaaaaag gctggcgacc agatgtctta tttatgacag
    31681 cgactccgat tcctagaaca ttagctatta cagcatatgg tgagatggat gtatctatca
    31741 ttgatgaact tccagctgga cgtatcccga tcgaaacacg ctgggtaaga acacctcaat
    31801 tggacagtgt actggattgg acgaaaaaag aactggcaag aggacatcaa atgtatgtca
    31861 tctgtccgct gattgaagaa tcagaagcat tagatgtaaa aaatgcagtg gaaatctatg
    31921 aaaaacttcg tgaactattt gcaccaaaat atgaagttgg cttgttacat ggtaaaatga
    31981 agaatcagga aaaagaagta atcatggaag ccttcaaaga caaccagatg cagatattag
    32041 tttcgactac tgtaattgaa gtaggggtaa acgtgccgaa cgcgaccgtc atgctgatca
    32101 tggatgcgga tcgatttgga ttggcacagc tgcaccaact tcgtggacgt gttggacgcg
    32161 gaagtgatgc ttcctactgt atcttagttg ctaatcctaa aaatgaacta ggtgtggaac
    32221 ggatgaaaat catgacagag accaccaatg gttttgtact aagcgaaaaa gatctggaat
    32281 tacgtggtcc tggtgaagta tttggcttcc gtcaatctgg tctgcctcaa tttgcgattg
    32341 ctgacttggt gacggatgga aatgttttgg aggtagccag agaagaggct gcagcccttt
    32401 ggcaaataaa ggattggcag atgcttcctg agtatcagcc tttagcgcaa agcctccaaa
    32461 tagaaaatca ggataatcgt tatttcgatt agcagactgt gctatacttt atactgatga
    32521 cggaaaaagg agtggaaaca atgaaaattg ccgtagatgc aatgggcgga gatcacgcac
    32581 ctcaagcaat tgtagaaggc gtggctttag cgcagcaaga ttttccagaa gtagaattct
    32641 tactttacgg aaaagaagca gaaatcaaga aatacttaac aaatgaaaaa aacatcacga
    32701 ttatccatac agacgaaaaa atcaatagtg atgatgagcc agtaaaagca attcgacgaa
    32761 aaaagactgc atcaatggtc cttgctgcac aagcagtgaa aaacggtgaa gcagatgctg
    32821 tattttcagc agggaataca ggcgcgctac tagcagcagg gttgttcatc gtaggacgta
    32881 tcaaaaatat cgaacgccct ggcttgatgt ctaccttgcc agtagtaggg aaagaaggtg
    32941 ccggtttcga tatgctggat cttggcgcta acgcagaaaa caaaccagaa catttgttgc
    33001 aatacggtat tttaggttct ttttatgcac gtaaagtccg aggtatcgga cgtcctcgtg
    33061 tcgcactctt aaacaacgga acagaagcaa caaaaggtag tgaagtgacg aaaaaagcct
    33121 atgaactcct tcagaatgaa acaagcttga attttattgg aaacgtagaa gctcgtgagc
    33181 tactcaatgg tgtggctgat gtagtggtca cagatggatt tacaggcaac gctgttttga
    33241 aatctattga aggaacagca atgaatatga tgaatctatt aaaatctgct attctaaatg
    33301 aagggatcaa aggaaaaatg ggcgctatgc ttttaaaaga cggcttacgt tctttgaaag
    33361 cagaaatgga ttattccaaa catggcggtg ccgttttgtt tggcttgaaa gcaccagtca
    33421 ttaaaactca tggagcaaca ggccccgatg ctgttcgcta tacgatccgc caaatccaca
    33481 caatgcttga gacagatgta gttggacaat tagtcgaaca atttgaaaaa agcgaagaat
    33541 agtatttgga tatctgaagc gatccgttcc attgaaaaaa aggtggacat tcctgaaaaa
    33601 tgccagtaaa attagccatg gtgtaggtaa ttgacaagtg tatgattctt ggaggtgaaa
    33661 aagttgactc gcgaagaagt atttaacaaa gtagcgaaaa ttatttcaaa tcattttgag
    33721 atagataccg ataaagtgac ggatgaattg aacatcaaag atgatttaaa agctgattca
    33781 attagtatta tggaattcgt tttagagctt gaagatgaat tcggtacgga aatttcagat
    33841 gaagacgctg aacaaattga aacagtcggt ggcgcagtag attatatcag cagccatctt
    33901 aaataatttc aaataaaagc aaagaaggat aaaaagctgc atgcagcttt ttatccttct
    33961 ttttttaatc tttttgacac gtaaaagtca tttttctgat aattctggcg ataaacagaa
    34021 attatgttgc aaagtaaagc ggttttctat ataattatta ataattcatt acacaaagat
    34081 aagaataacc tttgttataa aacgatttat tctgtgtaat gtcctttttt attaagaaaa
    34141 acttccattt aggaagcaga gaggggtatt cgattgtccg ataaccaatt attagaagtt
    34201 cagaacctac atacaggatt ccgactcaaa gatgactatt acgatgcagt agatgacgtt
    34261 tcatttactt tagacaaaaa cgagatttta gcaatcgttg gggaatctgg gtgcgggaaa
    34321 agtaccttgg ctactacgat tatgggatta cttgatccta ataacacaaa aattacaggt
    34381 gagattttat ataacgatct gaatttaatc gacctgaacg aaacgctcta taataaaatc
    34441 cgcggaaatg atatcggaat gattttccaa gatccgttgt ctgcattaaa tcctctcatg
    34501 agaatcgaag accagatcaa agaaggactt tcctatcaca caaagatgaa tgcagaacag
    34561 cgtcaagctc gtgcactaga attgctagaa caagtaggga ttcctaatcc tgcgagagtt
    34621 ggacgccaat atccccatga actatcaggc ggtatgagac aacgtgtcat catcgcaatc
    34681 gcaatcgcct gcaaacctcc aatcgtcatt gcagatgaac cgacgacagc cctagatgta
    34741 accatccaag cacagattct tgatttactg aaagaccttc aggaagaaac aaaaacaggg
    34801 atcatcttga tcactcatga cttaggagtc gtagcagaaa tggctgatcg agtggcagtg
    34861 atgtatggcg gacagttcgt tgaagtagca ggtgtaaaag aactgtttga tcatcctaag
    34921 catccttata cacgctcttt actgaactct ataccacaag aaggaaatca tgatgcagaa
    34981 ctccatgtga tcgaaggtgt cgttccttct ctgaaaaaca tgcctcgtaa aggttgtcgg
    35041 tttgcaccac gtattccatg gataccagca agcgatcatg aagaagagcc tatccttcat
    35101 gaagtcgcac cgaaccactt ggtacgttgc tcctgctata agcatttcca ctttagagac
    35161 gaaaaaggag aggtgtagat gacagaatta atcacaatca aagacctgaa agttcattac
    35221 cctattcgca gtggattctt caatcgagta acggatcatg tatatgctgt agatggtgtg
    35281 gattttatta tcgaaaaagg aaagacatat ggtttagtgg gagagtctgg ctctggaaaa
    35341 tctactacgg gaaaagccgt tgtgggatta gaaaaggtaa cagccggaca aatcatgtat
    35401 gaaggaaaag atgtaacgaa gcgaagcaac cgcaaaaaaa tgggttataa caaggatgtg
    35461 cagatgatct tccaagattc aatgtccagt ttgaatccta aaaagcgagt gttggatatc
    35521 attgctgaac ccatccgaaa ttttgaacgg ttaagcgatc aagaagaaaa gaaaaaggta
    35581 aaaggactgc tagatatcgt tgggatgccg gaagatgcgc tatataaata tcctcatgaa
    35641 ttttcaggcg gacaacgtca acgtctagga gtagcccgtg ctgttgctac caatccaaaa
    35701 ctgatcgtag ccgatgaacc tgtatctgct ctggatctat ctgttcaagc gcaagtattg
    35761 aatttcatga aacgaatcca gcaagaatac ggcctcagct atttattcat ttcacatgat
    35821 ttaggtgtag taaaacacat gtgcgacaat atcgcaatta tgtacaaagg tcgatttgta
    35881 gaaatcggta caagagaaga catttataat gacccgcgac atatctatac gaaacgtctg
    35941 ctttcagcta ttccgcaaat cgatgtagaa aatagggaaa gccacaaaga aaatcgacga
    36001 agagtagaac aagagtatat ccaaaaccaa aaagaatact atgatgcgac tggtcgagtc
    36061 tacgatttgc gtacgatcac aactacacac aaagtggcgt tgaaagatgg aggtgcaagc
    36121 taatgtggaa aacgattctg cgacgtgttt tattgatgat cccgcaagtt attattttaa
    36181 gtgttctgat cttcttatta gcccaagcga tgccggggga tccatttacc ggtttgatca
    36241 atccaaatca ggatccggca gtgatcgaac agatgcgaca agcagctggc ttgaatgacc
    36301 catggtatgt ccagtacttc cgttggatcg gaaatgcttt gcaaggcgat tttggtcaaa
    36361 gtttcttata caaacgctct gttgctgact tgatcggcga acggatcatc aacactttat
    36421 atctatcgat cttgacagtt gtccttactt atttgattgc tgtgcctctg gggatgcttg
    36481 ctggccggta tcaaaattca atcttggata agattgtcgt aatctacaac ttctttagtt
    36541 ttgctgttcc tttatttatc ttcggcttga tcatgctatt tgtttttggt tatcgtttag
    36601 gctggttccc aacaagtgga tcacaaacac taggtttgca aggtggattt atcactcaat
    36661 ggatagaccg tttgaaatat attctgttac catcaattac ccaagcattt ttggcgactg
    36721 ccgtcacaat ccaatatctg cgaagtgaag taatcgattc gaaatcgctc gattttgtca
    36781 gaacagcccg ttccaaaggg gtaccgacga ataaagtatt cagtcgacat attttccgaa
    36841 atgcagcgtt gccgatggct tctcaaatgg ggtatgaaat cacttcgttg attgctggtt
    36901 ctgtagttat cgaaaagatt tttggttatc cgggagtcgg aaaactattt attgattcca
    36961 tcggccaacg ggactatacc gtgatcacat ccttagtatt gattttagga atcgcgacgc
    37021 tagtggggac attactttca gatatcatca tgagtatcgt tgacccgcgt attcggattc
    37081 aataaaacca atcagaaagg agaatggatc gatgagtgaa aaaaacaata cagcagttca
    37141 agaaagtatt cctcctatgg ggatacgaat gattgctcga gaatttaaaa aagataaaat
    37201 tgctattttt tcattaggtt tgctagtggt tttattatta gtgatcttta tcggtgcgat
    37261 gctgaccgat caagacaaag tgatgtatgt tagtatcttc gacaaatacg ctgcaccagg
    37321 aacagtttcg acacaaggac aaaagttcat tctgggagca gatgaaggcg gacgtgatgt
    37381 attaggacaa ttgatcatag gtgctagaaa ctctgttacg atcggatttg cgatcacgat
    37441 ccttacttcg atcatcgggg ttggattagg gatcatctct ggctactacg gagggatcat
    37501 tgacaacatc ttgatgcgga tcgttgattt tatcatgatt ctaccgatca tgctgatcat
    37561 tatcgtcttc gtatcgatta tttccagata caatgtctgg tcctttatat tcatcatgag
    37621 tgcattttat tgggtagcta aagcccgatt attccgaagc aagacattat ctgaagcaag
    37681 aagagattat gtcagtgcct caaaaacaat gggaaccaat gattttaaaa tcatgttccg
    37741 cgaaatcatg ccgaatctaa gttcattaat cattactaat ttgacgatga actttgcggc
    37801 aaacatcggt atcgagacaa ctttgacttt cttaggtttc ggcttgccgg caaatgtacc
    37861 tagtttaggt acattgatcg gttatgcaag taacggagaa gtcttagtga atcggcaatg
    37921 gatctggtta cccgcatcaa tccttatttt agttttgatg ttgagtatca attatgttgg
    37981 acaagcattc aagcgttctg cagatgcgcg ccaacggtta ggctagtata gaagcgaagg
    38041 gggaaatagg aatgaagaaa acgatttttg gatttgcagc gctgatgtct gctgtcgttc
    38101 ttgcagcatg cgggggcgga ggtacagata cctctggaaa caactctgga ggcaacggca
    38161 ataacaaaga ggaattaact tttccaattg caacaaaaaa taatgatgat gcaatcgaag
    38221 acggcgaatt agaagctgcg gtcgcaacgg acagtcagtt taaaggattg ttccagtggg
    38281 agttttacca agattcatat gatgcagctt ttatggctcc ttctcatgaa ccgctatttg
    38341 caaacgatga cgatttcaga atcacagacg acggagctgc aacgcttgat ctagatgaag
    38401 atacgaaaaa agcgacaatc aaagtaaaag acaacgtcaa atggtcagat ggtgaagatg
    38461 taacggcgga cgatgtgatt ttcccttacg aaatcattgg gaataaagat tacactggta
    38521 tccgttatga cgacactttc cgtaacatcg taggtatgga agaatatcat gatggaagtg
    38581 ccgacacaat ctccggaatc aaaaaaatag acgacaaaac agttgaaatc gaatataaag
    38641 aagtaaaccc aagcatgctt caatcgggtg gtggtatctg gtcatatgca gcaccaaaac
    38701 atacgttaga aggtgtagca atcaaagata tggaatcaag cgatcaagta cgtaaaaatc
    38761 cagtgacttt tggcccttat tacatgagta atatcgttgc aggagaatca gtagaatact
    38821 tgccaaacga gcactactgg aatggtacgc ctaaattgaa aaagatcacg atgaaatctg
    38881 taccgatggc aagtgcaact gaagcattga actctaaatt atatgatatg attttccaaa
    38941 tgccaacaga tacttacgat acctataaag aaattgctgg ctatacaaac ttaggccgtg
    39001 aacaaacttc ttatacttat ctaggattca agttaggtaa atggaatgca gatacaaaga
    39061 gtgtggaata caatccagat tcaaaaatgg ctgataaatc attacgtcaa gcaatgggct
    39121 atgcattaga taataatgca gtaggtgaac gtttctatgc aggtttgaga agcaatgcga
    39181 cttcattgat tcctccagta ttccagtcat accatgatga tgagatgaaa ggattcacac
    39241 aagatctaga caaagcgaaa aaactattag atgatgctgg ctacaaagat gtggatgacg
    39301 atggtttaag agaagacaaa gatggaaata aactaacaat caactttgct tcgatgtccg
    39361 gtggggaaac agcgcaacca ttggcagatt actatatcca acaatggaaa gaaattggtt
    39421 tggatgtcca atacacaaca ggtcgtctga tcgaattcaa ttctttctat gataaattag
    39481 aaaacgatga tcctgaaatt gatgtttacc aagctgcttg gaatacagga actgatccaa
    39541 atccaagtgg actatgggga ccaaatgctg cgttcaacta cactcgttat gaatcagaag
    39601 aaaatacaaa attgatcaac gatatcagtt caagcaaagc atttgatgaa gagtaccaaa
    39661 aagaagcata tcaaaaatgg caacaatatg catttgaaga agcatttgcg attccaacgt
    39721 tgttccgtaa tgaagtattg ccagtcaacg accgtgtcaa agactgggat tggtcttatg
    39781 atgtaccaaa cccatgggca aatgtttctg ttacagcaga ttcacgttca taatcactaa
    39841 aaatgaccga aaaagggcga tgtccttttt cggttttttg atatttttct gtttatttct
    39901 ctaatattca ggtcaaggcg ctgatttcat gacttctcca ataaacggtg ttcaaagtcc
    39961 agtttctcgg tattaagtca aatttatgca aaaatatgga aagccatttt cacaaaattt
    40021 tttcttcata ctcgaaacta aacgaatttt tcacaacttc tcgtcaatca ctaggattat
    40081 taaagcttta cttacctttt gaccgaacca tttcaaattt gacaaaaaac cagtataata
    40141 aggaagtatc gaaaaaatat ccataaaagg aatgtggaaa atggacaacc agctgacaaa
    40201 agaactaaaa gaaaactata acatcgtttt tcacgatcta aatttgcttg aacaagcttt
    40261 tacccattca tcctatgtga atgagcatcg caatctgcaa ttatcggata atgagcgact
    40321 tgaattttta ggagatgccg ttttagaact gatggtttct cagtatttat tccgtttata
    40381 tcctcatttg ccagaaggaa aattgacaaa aacacgagct gcgatcgttc gcgaagacag
    40441 cttgtcgaaa tttgccaaag aatgtcactt tgatcaatat gttttgttgg gcaagggaga
    40501 agagaattca ggaggacgta cgcgaccagc attgctttgc gacctattcg aagctttttt
    40561 aggcgcgtta tatcttgacc agggattcga cacgacccat gcattcatcg aaaaagtgat
    40621 ttttcctaaa gtcaaagcag gtgctttttc acatgagatg gatcataaaa caaaactaca
    40681 agaagtcttg caaaaatcag gtgatgtatc aatcgaatac cgattgatca atgaagaagg
    40741 tccagctcat gaacgagtat tttggatcga agtttatgta gatgatcaat tgattggcac
    40801 tggacaaggg aaatcgaaaa aattagcaga acaagctgcg gcggaaaatg cattggcagc
    40861 actgtaaaag taagtgaggg aaagctttgt atttgaaacg aattgaaata gccggtttta
    40921 aatcatttgc agacaagaca gtcattgatt ttgaaaatag cgtcacagca gtggttggac
    40981 caaatggcag cggaaaaagc aatattacag aggctatccg ctgggtatta ggagaacaat
    41041 ctgctaaaag tctgcgaggc ggaaaaatgc cggatatcat ctttgccggt tccgataccc
    41101 gtaagcagct gaatattgca gaagtcacag tgattttaga caatagtgat cattatctgc
    41161 cattggagta caatgagatc agtgtaaccc gccgttatcg acggactggg gaaagcgagt
    41221 ttttcatcaa taaacaaagc tgcagattaa aagatatcca agaattgttc ttagattctg
    41281 gattaggaaa agaatcgttc tcaatcattt ctcaaggaaa agtagaagcg attttcagta
    41341 gtaaaccgga agaccgtcgt gggatctttg aagaagcagc tggtgtcttg aaatacaagc
    41401 agcggaaaaa gaaagcagaa cagaagcttt ttgaaacaga agacaacctc agccgcgtcc
    41461 aagacatcat ccacgaattg gaagaacagt taactccttt ggccgcccag agtgaggcag
    41521 caaaggagtt tttacggcta aaagaaacac tgactcaaac cgatgtctct ttgatggttg
    41581 ctgaaatcaa gacagcaaaa aaagattggg acaacaaaca agcacagctt gcgaaattca
    41641 atctagaatt aggcaaacta tctgagtcga tccaagaaca agaatccatt ttggcgaagc
    41701 agcgtaaaga aaatgcgcaa gccgatcgtc tgatcgaaaa aaatcagcaa gtattattag
    41761 atctttcgga aaaactgaag cagacagaag gacaaaaaga tgttttgcag gagcggacaa
    41821 agcatacaca aaaaagctcg caagaatatc aaacttcatt agcagaagca caaaaaaagg
    41881 ttaaacattt tgaaaagctt caagaaagct tgatgaaagc agcagcagaa aaagaaacag
    41941 agatccaaaa agctgaagca aatctcataa aaacacagca agaattagaa aaataccaaa
    42001 aatcaacgaa agaattattg gcagaattaa gagatcaata tgttgatttg atgcaagaac
    42061 aagcagctgt aggaaacgaa ctgaagtatc tagaacgtca atatatacaa gaaacagcaa
    42121 aaagcaagca gacgttagcc aagcaatcgg aagtagaagc atcagtagac cgattgatct
    42181 tacaaaaaga agaattgaca caaaagcagg cgcagctaaa atcatcttta actgaaacaa
    42241 aagagaagtt agaaatgatc caacaaaacg ggaaaaagtt ccaagaagca ttagcaaaag
    42301 aacagcctaa aatgtatcaa ttaatgaatc aagtccagca gctacgtgct cgtaagaaaa
    42361 gccttcaaga aatccaagaa aactattttg gtttttacca aggggttcga ttggtcttgc
    42421 agcataaaca gcagctttcg ggtattgtcg gagcagtggc tgaactgatc gatgttcctg
    42481 cagatttcac gttagctatc gaagcagctt taggtggggc agcccagcat gtcatcgttg
    42541 aaaatgaaaa agatgctcgg caagccatca cgtatttgaa acagcaaaga ggaggaagag
    42601 caacattcct tccactgacg acaatcaaac caagacaatt accggctcat atattgacac
    42661 aagcagcagc tgtagaaggg tttataggga ttgccagtga acaagtcagt tatcccgatc
    42721 aaatccaaac tgtggttcaa aacctgctag gaacgatcct tttagccaaa gacttaacta
    42781 gtgccaatgc aatcgcgcaa acgatccgct atcaatatcg agtggtttcc ttagaaggtg
    42841 atgtgatgaa tgccggagga tccatgacag gtggagcgaa taaacgagga aaccaaggca
    42901 gtttgtttgt acaaaatcaa gaattgaaac agttgactag tgaatttgaa gaagcagata
    42961 aacaactcca agcacaagaa aaaaaagttc aggagctgca acaagaaaca gctcgtttag
    43021 ccgaagaaca agaagttttg cgtacacgag gcgaacaatt acgttttgaa gaacaagaag
    43081 cgacaaatca gctacaaaac atcataaatg aacttgaacg ttttgaaaaa gaaaagcaaa
    43141 tctcaacttt tgagacacgt gaactgcagc agtttatcga agattacgaa aagcaaacga
    43201 acgaattgaa agacaaacaa acagatcttg aatcgcaacg acaaaaaatc gacgaagaaa
    43261 tcaaatcgtt aagtcaagaa agcgaccaga tggaagccag aagagcacaa gtacaaagtc
    43321 aaaaagcaca agaacaagca gatcttgctg tcttgaaaga gcagtttaat catctgcaga
    43381 tccagctccg cggtgcccga gtccaaaaag cagaggcaac cgaacgtcaa gaagcgatag
    43441 aaaagcagtt ggcgacattg acagcagact tttctgatca tgaagtcaca gaagaaagtt
    43501 tggaaaaaca aattaacgaa ttatctgctc agcgagaaac attaaaagcc gagttggcaa
    43561 aagccaaaga gcagcgagat agaaggcaaa aggagatcga taagcttgaa gcagtcttgg
    43621 cagagcgtaa tcgtgagcaa aaagcacgac tgtcggaaca atccaaatta gaagtccaaa
    43681 aagaccgagc tgaaatgatt ttagataatc atttgaccta tctgcagtca gaatatcagc
    43741 tgacatttga gaaagcttcc caagactatc aagaaacaac cgatatcgaa gacagtagaa
    43801 caaaggtttc atccttaaaa gaacagattg aaaaactggg accagtaaac ttaaattcaa
    43861 tcgaacaata cgaacaagtc agtgaaagac atacattctt agcaacacag cgagatgatc
    43921 tgttagcagc gaaaaaccaa ttgtttgaaa cgatggatga gatggatgat gaagtgcgga
    43981 caagattcaa agaagtattt gaagctatcc gtcaagaatt caaaattgtc tttccaaata
    44041 tgtttggcgg cggtaaagct gaattagtac tgacggaacc aactgatttg ctgaaaacag
    44101 gtattgagat tgaagtacaa cctcctggca aaaaactgca aagtctaagt ttgctttctg
    44161 gaggagaacg agcacttaca gccatcgcgt tgctcttttc cattatccgt gtctgtcctg
    44221 ttccgttttg tatcttagat gaggtagaag cagcgttaga tgaagccaac gtgaaacgtt
    44281 ttggtcgtta cttgagcgat ttccaagatg acacacaatt tatcgtagtc acacaccgca
    44341 aaggaacgat ggtcgcagca gatgtactgt acggagtgac gatgcaggaa tccggtgtat
    44401 caaaaatcgt ttctgtacgg atggaagata tcaatgaaga ggcgaaaatc aacgaaacga
    44461 aagtgtagga acgaaaatga tcaaattagt agcaatcgat ttggacggta cattattaaa
    44521 tgaacaaaag ctgatttcag atgagaataa acaagcatta gcacaagcaa aacagcaagg
    44581 ggtcaagatc gttctatgta caggacgccc cttagctgcg atggcgcatt atctgcaaga
    44641 attaggactg gtagatgaag gtgactacag catcactttc aacggcggtt tggtacaaaa
    44701 aaatgatact ggtgaaatca tggaaaagaa agtgatggaa gtatcagata tccaacgctt
    44761 atacaaactg gctcagcaat tggatctgcc actagatgtt ttgtctgaca atgtggtttt
    44821 acagctgcct agtgccccaa ggaagcaatc cttgtacaat gtgttgaata agctgctgca
    44881 attccaacca gcggatataa gcgatattac agatgaattt gtgcttaata aggcagtaat
    44941 cgcttatgac caagaagaat tagatcctaa aatcaaagaa ataccagcag aattccatga
    45001 aatgtatgag atcatcaaaa caagaagtat gcttttggaa tttatgccaa aaggtgttac
    45061 aaaagcttat ggtatttctt tattggcaaa agatcttggt ttgaaacaag aagaaatcat
    45121 ggcgatcggt gatgaggaaa atgatttacc gatgatccaa tatgctggac taggcgtagc
    45181 gatggagaat gctgtgcctt tcgtcaaaga agcagcagat ttcgtgacag ccagcaatga
    45241 agaaaatggc gtagccaaag tgatccaaaa atttgtatta gagtaggggg agtcaaatgg
    45301 gattttttga taaaatcaag cgtgctttta ctggcgaaga gaaaacagaa gaagttgaag
    45361 tacaggagaa gtacgacaag ggtttagaaa agacgcgtaa aacatttggt gaacggatga
    45421 atgagttgtt tgccaatttt cgaacagtcg atgaagactt ttttgaagaa ttagaagaaa
    45481 cacttatcgg tgcagatgta ggttttgaaa cagcgatacg aatcaccgaa gcattacgtc
    45541 aagaagtgaa actcagaaat gcgaaaaaat cggcagaagt ccaaaatgcg atcatcgaga
    45601 aacttgtgga tctctatgaa gcggaaggaa tcaatgaagt aaatgaacta aatatccaag
    45661 aagacggact aacagttatt ttgtttgtcg gtgttaatgg tgtagggaaa acaacaagta
    45721 ttggtaaact tgcccatcag ttcaaaaacg aaggtaaaaa agtattgatg gcagcagcag
    45781 ataccttccg cgctggagca atcgaccagt tagttgtctg gggcgaacgc gctggtgttg
    45841 aagttgttcg tggcaatgca ggaggcgatc cagcagctgt cgtattcgat gctttggaaa
    45901 gagcaaagac agagcaggca gatgttttac tagttgatac tgcaggccga ctgcaaaata
    45961 aagtgaactt gatgaacgaa ttagaaaaaa taaaacgagt aatccagcgg gaattaccag
    46021 aagcacccca agaaacactt cttgtattag atgcaaccac tggtcaaaac gcgatggttc
    46081 aagcaaaaca attcaaagaa acaacagatg tgaccggtct tgttttgaca aaattagatg
    46141 gtacagcaaa gggcggtatc gtacttgcta tccgtaatga attgcattta ccagtgaaat
    46201 tggtcggtct tggtgaagga atcgatgact tggagccgtt tgatccaaat gattttgtcg
    46261 ttggattgtt caaaggatta ctaaaagaag aataacccat gtctaaaaag caggagctgt
    46321 gacaaaagtt gcagctcctt gtttgaatga ttgtttttaa catagctgtg tttttgatgc
    46381 cttcattttt atacttattt gtaagcggtt ctcaaacaat ttcgttcttt ttcttagact
    46441 ttttgattat aattagattc atatgaattg gaggtcactt aatgatgaat tttaagcaat
    46501 tattattgca tgtcaatgcg cgccctttta tcgaccaagc tcgatttggt atagaacggg
    46561 aaggacagcg ggttgatctt gcaggaaatc tagcaaaaac cgatcatcca gcaatctttg
    46621 gcgatcgatc ctatcacccc tatatccaaa cagattttag cgaaacacaa acagagatga
    46681 tcacccctgt taccgattct attcccgaat tatttcagta tctcgctgct gtttatgatg
    46741 tgactgctcg ttctataccg aaagaagaga tgatctggcc attaagtatg ccacctgcct
    46801 taccggaaaa agacgaagag atcattattg caaaattaaa aaatttcgaa gatgtcttgt
    46861 atcgacgtta tttagcaaaa gaatacggga agcgaaaaca gatggtaagc ggtattcatt
    46921 tcaattttga atttggcgat gagttgctaa gaacattgtt cagccatcag gaagaatttc
    46981 aagatttttc cgaattcaaa acagaacttt atttgaaaac agcgagaaac tttatgcgct
    47041 atcgctggat gatcacttat ttattcggtg cttcaccaat gagtgagaag aactactttt
    47101 tagatgaatc acatccgcaa gaacctgttc gcagtattcg caacagtgcg ctgggctata
    47161 cgaatcatcc aaatgtgaaa gtttcctatg cttctatgaa acagtattta gcagatatcg
    47221 agcgaatgat cgaagaaggg aaactttcgg aggagaaaga attttataca ccgcttcgtt
    47281 tccgaggcgg aaagaaagtc gcagatttag caacaacagg tgttcgttat attgaattgc
    47341 ggaatatcga tttgaatcct tatgcaagat tgggtatcaa tccagagcaa gttcggttct
    47401 tacaattatt cctgatgtac atgttatgga cagaagaaaa agaagactgt gaccaatggg
    47461 tagcagaagg tacgactcga aataacaaag tagcactaga acaaccatca gatcaaacag
    47521 aatttcatca agaaggtaga gaaattcttg aaggaatgaa gcaaatgctg gttgaattgg
    47581 attggttgga ttctctttat ttagtagagg aagcattgac tcaaatggat catcctgaac
    47641 aaacgttagc agcgaaactc tatcaagaag cacagctatc gagtcagcaa gaagttgctg
    47701 tggcattggg acatcaatat tataaagaaa gccatgaacg tccctatcag ttggccggtt
    47761 ttcgcgaaat ggaactttct actcagatat ttatgttcga tgccatccaa aaaggtgtcc
    47821 aagtcaaagt attagatgag tcggatcaat ttttgcgtct gcaattccaa gaccatgtag
    47881 aatatgtgaa aaatgcaaac atgacaagta aggacagcta tatcgtccca cttatcatgg
    47941 aaaacaaaac agtaacgaaa aaagtcttaa aagaagctgg gttccgggta ccaggaggcg
    48001 cagaattttc atccatggaa gaagcggtaa aagcttatcc gagatttgcc gagcaggcat
    48061 ttgtgatcaa acctaaatca accaattacg ggttaggtat cacgattttc aaggaaggag
    48121 ctagtctgga agattatcaa gcaggtttag ccattgcttt tcgtgaagac agttcggttt
    48181 tagtagaaga atttatgccg ggaacggaat atcgtttctt tgtgatcgac ggagaagtcc
    48241 aagccatcat gttgcgagtc cctgctaatg ttattggtga cagtatccga acagtgaaag
    48301 aacttgttga agaaaaaaat agtgaccctt tgcgtggaac gaatcatcgt gcacctttag
    48361 aattgatcca attaggtgaa ttagaacaat tgatgttgaa agaacaaggg ttgacgatcg
    48421 aatcagttcc ccaagccaat caaattgttt atctaaggga gaactcaaat atcagtacag
    48481 gtggtgattc gatcgatatg actgatgaat tttctgaagc ttacaaaaaa atcgccgttt
    48541 ctgcggtaga agcactagga gctaagatta gtggtatcga tttgattata ccagataaag
    48601 aaatcgatcc tacaactgat aaaaaagcat atgggatcat cgaagcaaat ttcaatccag
    48661 ccatgcatat gcatgtttat ccttttgcag gaaaaggcag aagattgacg atgaatgtat
    48721 tgaaattgtt atatcctgaa gtattttaaa agaaaaagct tttgacagat tgtcctattt
    48781 gatgtcaatc tgatcaaaag ctttttttgc atgtaaaaat ttatgtgttt tttcgtttta
    48841 aaataaacga tcccagaagc tttttttctt ttttggtttt tctttttcag ctggcgaaga
    48901 gttttcttct gggtattttt tttcgatatc aatcacaggt tcatttactg cttcttttgc
    48961 tgttaagagc aatccgaatt cctcaggatt tgcagtgacg taatcgttga ctacagtgaa
    49021 acggctattg tttttcgttg ctagctggat atattggttt tggacagaaa ggggtagagc
    49081 cccattcaag agtatggaag catctggatg ttttttgagt tcttttaaaa agttttcttt
    49141 gttttttggt tggatcattt cagcaacagt catactaaga tagcagcgtt ccctgaatgt
    49201 ccctaaatat ttatgctgtt cttcagggtt cactaaaggt gtaccataaa gtcccttatc
    49261 caaatggctt tttacatcat cttgtgccat aaaaaatacc ctccttcttc tctttgtctt
    49321 tcttacgatt atagcatatt cccaataata cctaaaacat atgaaaaagc ggttgctttt
    49381 gttcaacgat tcacttaaaa taagaatgaa aatcattctc aattagaaag gtggattgga
    49441 tgcgctacgg acgactagta gcattattag ttattttaag tagtatttca ttgttcatcg
    49501 gagtatcgaa tgtacaattg tcagaactgc tccagttaga tgggcaaagc ttacaaatct
    49561 tgctagtgac tcgtttgcca cgaacgattt gtttgatcct tgtgggagcg accagtagta
    49621 tttgtgggtt gatcatgcaa catttgaccc aaaataaatt tgtttcacca acgactgcgg
    49681 gcacgatgga tagtgcgcgt ttaggtattt tagtggctat gattttccta cctggtgcat
    49741 ccttgattgt ccgatccttg acagcatttt gctttgcttt tgcaggaaca ttgctttttt
    49801 tatcccttac gcgattgttc ctccagaaaa atcaattgat gcttccgttg attggagtca
    49861 tgttagggaa tatcattggt tcagttgcta ctttttttgc ttatcaattc cagttggtac
    49921 aaaatatgac ttcatggctt caagggaatt ttgcgactgt gatacgagga aattatgagt
    49981 tattgtatgc tgttgttcca ttgttgctct tggtttggct atttgcttac cgatttacga
    50041 tcattggtct gggcgaatcg tttgcagtaa atctgggaat agattaccag aagatgcagt
    50101 ttttaggcat tggcttagta tcattggcta gtgcagtcat gttgatcatg gtaggaagca
    50161 ttccttttat cggagtgatc attccgaatc ttgtctctag aatatatgga gatcaagtgc
    50221 acaaaacaat tggcgtaact gctttagcag gtagtttgtt cttagtattt tgcgatcttg
    50281 tcgctcgcgt gttgattttt ccttatgaaa taccagtcag tgtgatcgtt ggaatcatcg
    50341 gtggggctat cttcctttat cttctgataa ggggacgacg atatgcttaa aaaaaagcca
    50401 tctattttta ttggtatgct tgttcttgtt ttatttgtta caggaatgta cttgacgatc
    50461 catacatatg gaaactggca ttttgcatgt gcattgagga gtaagaaaat ttttgcattt
    50521 atccttgtct cgctagctgt cagcagtgcc acaatcagct ttcagacaat tacgcataac
    50581 cagtttttga ctccttcagt attgggactt gagtcgttat atgtccttgt ccaaacggtc
    50641 cttttcttct ttatcggagg agtgacgatg cttcagcaga caggtacagt ttttttctta
    50701 ttgaacgttg ggctgatggt cgggctgagt ctattgttat ttttctttct tttgaaaaaa
    50761 atgagagcga atcttttttt attactgatg tcagggatga ttttaggtac gctttttggt
    50821 agtgtcagta cctttttaca agtcatcatg gatccgaatg aatatgattt gcttcaaggc
    50881 agattatttg caagctttgg caatatccag agtcagtatc ttttgcctgc ttctttgatc
    50941 attatcggct gctggtacct gttatttcga tatcgacatg tgctagacgt tttccatctc
    51001 ggaaatgaac aagcagtaaa cctcgggata gacacagatc gttttgaatt tttgatttta
    51061 tgttgtgtca gtcttttgac agggacatca acggctcttg tgggtccagt tactttttta
    51121 gggtttattg tcgcaaatat cagttatcgt gtcttttcta cttatcgtca tggtcagcta
    51181 tttatcggaa gctttctggt agctatgctg tttctgacag gaggacagct cgcagtagag
    51241 cagattttcg gctggaatac aacagtgagt gtcgtcgttg aatttgtcgg aggaatttat
    51301 tttgtcacaa aattgattcg cgaaaggaag agtatcctat gattgattta caaaaggtca
    51361 ataaactgta ccatggaaaa tcagtggtta aagatgtaca gttaacgatt cctgaaaaga
    51421 agttgactgc ttttatcggt ccaaatggtg ctggaaagtc aacggtgttg tcgatgatca
    51481 gtcgtttgat accaaaagat acaggtgaaa tctatttaga ccataacgaa gtaaaggctt
    51541 ggaaatccaa tgaattagcc aaaaaattat cgatcctacg acaatcgaat gaaataaatg
    51601 tccaaatcac cgtgaaagaa ttagtagaat ttggacgatt tccttatacg aaaggaaaat
    51661 tgacgacaaa agacgaggaa atcgttcagg aatcactgga acacattggg ttagaagaaa
    51721 tagcggatca atcgattgac actctttcag gcggtcaact ccaacgtgcg tatattgcaa
    51781 tggtgctagc gcaagacacg gattatattt tactggatga acctttgaac aatctagata
    51841 tgaattttgc ggttcaaatc atgcagattt taaaaaattt agtacaagaa atcgggaaaa
    51901 caattgttat tgttcttcat gatatcaact ttgctgcaag ttatgcagac gaaattgttg
    51961 caatgaaaga tggacagtta tttacgcaag gaacgaccca agaaatgata aaaaaagatg
    52021 tattggatga attatacgaa atggacatac ggatttgtga gattgaaggc cgcagattct
    52081 gtctttattt ctaaaactaa cattaggaga gaagagatga aaaaattagt agtaggtatc
    52141 ttgattctag catcatttgg tttagcagca tgtggaaata gcaacaacac cagtcaggca
    52201 gacacaaaaa aaagcagcac acaaactgaa actacattga cgataacaga tagtaatgga
    52261 gaccaaatcg aggtgccaaa taatccagaa aaagtcgtcg tattcgacaa tggttcttta
    52321 gatacgatgg atgctcttgg tgttggagat aaggtagttg gagcagctac aagcagcctt
    52381 cctgagtatc tttcatccta taaaaaagta gaatcagcag gtggaataaa agaaccagac
    52441 ttagaaaaaa ttaatcagct tcagccagat ctaatcatca tttctggccg acaaagagat
    52501 tttcaaaaag atctaagtca aattgctccg accattttcc tttctttaga tgcgaaaaat
    52561 ccatgggaat ctttccagca aaatgtcact gctttagggg agatctttgg taagcaagaa
    52621 gaagctaaaa ctcaattaga ggaattatct agtgcaatcg atcagacgaa aaagaaagca
    52681 gaagctactg acaaaaaagc actagtcaca cttgtgaatg aagggcaatt atcagcctac
    52741 ggatctggtt ctagattcgg tttcatccat gatttatttg gctttgaaca agcagatgat
    52801 caaatcgaag catccactca cggtcaaagt gtttcttatg aatatgtgct ggaaaaaaat
    52861 ccggatatct tatttgtagt agacagaaca aaagctattg gtggagacga cagcaaagat
    52921 gatatttctg ccaatgaact ggtagcacaa acgaatgctg gtaaaaatca gcagatcatc
    52981 tcccttgaac cagatgtctg gtatttaagc gggggcggtt tagaatcaat gaaactgatg
    53041 atcgaagatg tgaatcaagc atttaaatag cataaataac agaggattaa actctcatac
    53101 tatgtaacaa taatgtttct tacattctta aatagcaaga gcctatcctc aaagaagtta
    53161 tcaaaaacca tccgtaaaat cgtattgatg attttacgga tggtttttat ttatttgaga
    53221 aatctttttt caacgtgaat tcattatcta catcatacgg gttgattcta gaatggggag
    53281 tggcaaaaaa tagtgtgatc cattttttca gcatcaagat cgcctccttt gatttgaatc
    53341 aaaggtacaa agcgaaactt agataaaact taaatttaga tatttttatt ttgtaccgat
    53401 ctcttcttta aacgatgttc catctgctgc ttctcggcaa taagtccact agactagaaa
    53461 atatgagaag ctattttctg tccagcgttc ttattactca aaacaaatcg cagttgtcac
    53521 aatctcttct aaacgatgtt ccatctgctg cttctcggca ataagcccac tagactagaa
    53581 aatatgagaa gctattttct gtccagcgtt cttattactc aaagcaaatc gcagttgtca
    53641 caatctcttc taaacaatgt tcaatcagct gaccttcggt attagctcaa agcactgatt
    53701 tcacaacctc tatttaggca tgtgtctcag caagcggttg atagttgatg atctgcattt
    53761 ttcgataaaa atcggcggga agcttactcc accgttttag taattgatag aaataactct
    53821 cttctgcttt gattttatac tcgcttaata tcaatccaaa actattcgtt ttttttgaag
    53881 ctaatttttt ataaatatcc aatgctttgg ttttatcttc attgacaaag agtgttttta
    53941 cttcaatata agaaccctcg atattttgtg tttcttcgat aaaatagatg ttttttatat
    54001 attccttcat agtgattcct ccaaagaagt cttttatttg ataagtttac tctaccgaag
    54061 agttgttaat aatccgtgaa caaaaagtaa ttctttttcc aatagttgtt aaaggttttt
    54121 tattttttat agtatttttt gttatttaag aaaggaataa ggttaaacaa ataacaggtt
    54181 gctttttggg tctttttccg ttcaagaaac tgaacgaaga aaagggaaag ttgtctcttt
    54241 tgtgataaga gaaatcataa taaacgaatg acttactttc caataaattg agaacagtca
    54301 gaaccagaca aattagttgc atctgatgaa taaagtgatt attctatgac atgaggtgat
    54361 acagatgaaa ttagaagtga caaaagaagc acaagaagta ttgaagaata aattagaagc
    54421 agacgatcaa cttttattag atatcgaaaa cggtgacggt ccatttgcag aaagccaagt
    54481 cagttgccaa ttggatacgg catttcgatt gatcattgtc aaaaaagata cacaaacaga
    54541 tctaagtctt tattctgtag tggctgatac accagttgga ccaatcaaaa tcaaagacag
    54601 tgcaatactt tacatggatg atccatccac acttgcttta gaaccaactt ataatagttt
    54661 acaattaaaa ggaccaagcg gcttgagaaa aggcaacttg caagttgttc gaaaagacta
    54721 gagggataaa atgggaaaat tggcgatcat cagcgaccta catgtggaca tcaataaatt
    54781 cggcgaatca gagctgatgc agctttggca agttttgcaa aagcacaaga tcactcggct
    54841 tcatctagcc ggagatacgg ctaataaagt agaccgttgc ctagctgttg tcgaattttt
    54901 cgtcaataaa ggattatcta cgacatttca tttcggcaat cacgagttgg cagatgtgcc
    54961 caatgaacag atgatggacc attttccaga cccacatttt ttaaatgaac ggtatattgc
    55021 tttaaatgag cagaccgttc ttttagggat gaatggctgg tacgactatc agttttccga
    55081 attgaaagat tacgaggcaa tcgtacgaat gaagcgtttg tattggtatg atcggttcat
    55141 ccagcgtggg aaaacagatc tcgaggtcaa tgcagaaatg cttgcagctg caaaaaattt
    55201 gctagaccag ctggaagcaa aaaaacttga ggtgatttta tccactcatt tcgttcctaa
    55261 acgggcattt atcatgtatc aatctgctcc ttatgagcgt tggaacaaat taaatgcatt
    55321 tttaggatca gaatcattcg gagaattact tgaccgttat tcaaatatca aacaagtagt
    55381 ttttggccat acgcatcgtc gctttgaaga taaatccatc ggtcacacga tttacagctg
    55441 cagacctttt ggttattatt atgaatggca gctgacccga gattttgtct tgaaagaaca
    55501 gttgctagac agctatgatc ctatgaaatt acgtgtcctc ttgcgtgccc atcacccagc
    55561 ttttcaggcc tatcaaacac aacatttgca agaggaattt gaacaagcga tgacaatcgt
    55621 tccgtattga gacagcatta gtaatgtgta aaagaaaata ccttgtaaaa cataaggata
    55681 agtaagagca gtagatccat ttatcgtgga tatgctgctt tttttgcgga aaataatcag
    55741 cgaatgttta tttgatcgga tgatttgtaa ctcgcagagt actagatgca agcgtgtatt
    55801 ctttttttga acgataatca caaaaaaaaa tataatatac attttttatt taattataat
    55861 taatattgat tgaagtctag gcagtcaagt cgagagt
//
LOCUS       DADQCX010000006        55197 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.006, whole genome shotgun sequence.
ACCESSION   DADQCX010000006 DADQCX010000000
VERSION     DADQCX010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.006"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            368..1471
                     /locus_tag="J8R83_000318"
     CDS             368..1471
                     /locus_tag="J8R83_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAZ9573481.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            1755..2435
                     /locus_tag="J8R83_000319"
     CDS             1755..2435
                     /locus_tag="J8R83_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAZ9573482.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            2525..3559
                     /locus_tag="J8R83_000320"
     CDS             2525..3559
                     /locus_tag="J8R83_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAZ9573483.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            3573..3908
                     /locus_tag="J8R83_000321"
     CDS             3573..3908
                     /locus_tag="J8R83_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573484.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            3892..6372
                     /locus_tag="J8R83_000322"
     CDS             3892..6372
                     /locus_tag="J8R83_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573485.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            6428..7987
                     /locus_tag="J8R83_000323"
     CDS             6428..7987
                     /locus_tag="J8R83_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9573486.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            7984..9348
                     /locus_tag="J8R83_000324"
     CDS             7984..9348
                     /locus_tag="J8R83_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9573487.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLTRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            9519..10589
                     /locus_tag="J8R83_000325"
     CDS             9519..10589
                     /locus_tag="J8R83_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573488.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            10604..11272
                     /locus_tag="J8R83_000326"
     CDS             10604..11272
                     /locus_tag="J8R83_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573489.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            11292..11870
                     /locus_tag="J8R83_000327"
     CDS             11292..11870
                     /locus_tag="J8R83_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9573490.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            12273..13184
                     /locus_tag="J8R83_000328"
     CDS             12273..13184
                     /locus_tag="J8R83_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9573491.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(13440..14357)
                     /locus_tag="J8R83_000329"
     CDS             complement(13440..14357)
                     /locus_tag="J8R83_000329"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAZ9573492.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            14559..14996
                     /gene="zapA"
                     /locus_tag="J8R83_000330"
     CDS             14559..14996
                     /gene="zapA"
                     /locus_tag="J8R83_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAZ9573493.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            15054..15602
                     /locus_tag="J8R83_000331"
     CDS             15054..15602
                     /locus_tag="J8R83_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAZ9573494.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            15717..18077
                     /locus_tag="J8R83_000332"
     CDS             15717..18077
                     /locus_tag="J8R83_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAZ9573495.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            18164..18478
                     /gene="trxA"
                     /locus_tag="J8R83_000333"
     CDS             18164..18478
                     /gene="trxA"
                     /locus_tag="J8R83_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAZ9573496.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            18660..20438
                     /gene="uvrC"
                     /locus_tag="J8R83_000334"
     CDS             18660..20438
                     /gene="uvrC"
                     /locus_tag="J8R83_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAZ9573497.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            20583..21482
                     /locus_tag="J8R83_000335"
     CDS             20583..21482
                     /locus_tag="J8R83_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573498.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            21475..22737
                     /locus_tag="J8R83_000336"
     CDS             21475..22737
                     /locus_tag="J8R83_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573499.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            22900..24798
                     /locus_tag="J8R83_000337"
     CDS             22900..24798
                     /locus_tag="J8R83_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAZ9573500.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(25097..25816)
                     /locus_tag="J8R83_000338"
     CDS             complement(25097..25816)
                     /locus_tag="J8R83_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAZ9573501.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            26153..26485
                     /locus_tag="J8R83_000339"
     CDS             26153..26485
                     /locus_tag="J8R83_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573502.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            26472..28475
                     /locus_tag="J8R83_000340"
     CDS             26472..28475
                     /locus_tag="J8R83_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAZ9573503.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            28494..28964
                     /locus_tag="J8R83_000341"
     CDS             28494..28964
                     /locus_tag="J8R83_000341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAZ9573504.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            28985..29569
                     /locus_tag="J8R83_000342"
     CDS             28985..29569
                     /locus_tag="J8R83_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAZ9573505.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            29584..30570
                     /locus_tag="J8R83_000343"
     CDS             29584..30570
                     /locus_tag="J8R83_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAZ9573506.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            30560..30871
                     /locus_tag="J8R83_000344"
     CDS             30560..30871
                     /locus_tag="J8R83_000344"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAZ9573507.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            30893..32674
                     /locus_tag="J8R83_000345"
     CDS             30893..32674
                     /locus_tag="J8R83_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAZ9573508.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMCG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            32667..34043
                     /locus_tag="J8R83_000346"
     CDS             32667..34043
                     /locus_tag="J8R83_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAZ9573509.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            34050..34685
                     /locus_tag="J8R83_000347"
     CDS             34050..34685
                     /locus_tag="J8R83_000347"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAZ9573510.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            34715..36070
                     /locus_tag="J8R83_000348"
     CDS             34715..36070
                     /locus_tag="J8R83_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAZ9573511.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(36262..37656)
                     /locus_tag="J8R83_000349"
     CDS             complement(36262..37656)
                     /locus_tag="J8R83_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAZ9573512.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            37748..38719
                     /locus_tag="J8R83_000350"
     CDS             37748..38719
                     /locus_tag="J8R83_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAZ9573513.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            38716..39498
                     /locus_tag="J8R83_000351"
     CDS             38716..39498
                     /locus_tag="J8R83_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAZ9573514.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(39667..40038)
                     /locus_tag="J8R83_000352"
     CDS             complement(39667..40038)
                     /locus_tag="J8R83_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAZ9573515.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            40172..40615
                     /locus_tag="J8R83_000353"
     CDS             40172..40615
                     /locus_tag="J8R83_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAZ9573516.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(40658..41467)
                     /gene="yidA"
                     /locus_tag="J8R83_000354"
     CDS             complement(40658..41467)
                     /gene="yidA"
                     /locus_tag="J8R83_000354"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAZ9573517.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(41486..42853)
                     /locus_tag="J8R83_000355"
     CDS             complement(41486..42853)
                     /locus_tag="J8R83_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9573518.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(42837..43667)
                     /locus_tag="J8R83_000356"
     CDS             complement(42837..43667)
                     /locus_tag="J8R83_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAZ9573519.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            43830..44267
                     /locus_tag="J8R83_000357"
     CDS             43830..44267
                     /locus_tag="J8R83_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAZ9573520.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            44343..44963
                     /locus_tag="J8R83_000358"
     CDS             44343..44963
                     /locus_tag="J8R83_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAZ9573521.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            45152..45658
                     /locus_tag="J8R83_000359"
     CDS             45152..45658
                     /locus_tag="J8R83_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAZ9573522.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            45675..46574
                     /locus_tag="J8R83_000360"
     CDS             45675..46574
                     /locus_tag="J8R83_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAZ9573523.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            46661..47545
                     /locus_tag="J8R83_000361"
     CDS             46661..47545
                     /locus_tag="J8R83_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAZ9573524.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(47737..47808)
                     /locus_tag="J8R83_000362"
     tRNA            complement(47737..47808)
                     /locus_tag="J8R83_000362"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(47773..47775),aa:Arg,seq:ccg)
     gene            47868..49202
                     /gene="rpoN"
                     /locus_tag="J8R83_000363"
     CDS             47868..49202
                     /gene="rpoN"
                     /locus_tag="J8R83_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAZ9573525.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            49405..50442
                     /locus_tag="J8R83_000364"
     CDS             49405..50442
                     /locus_tag="J8R83_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAZ9573526.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            50483..51484
                     /gene="gap"
                     /locus_tag="J8R83_000365"
     CDS             50483..51484
                     /gene="gap"
                     /locus_tag="J8R83_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAZ9573527.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            51594..52784
                     /locus_tag="J8R83_000366"
     CDS             51594..52784
                     /locus_tag="J8R83_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAZ9573528.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            52888..53643
                     /locus_tag="J8R83_000367"
     CDS             52888..53643
                     /locus_tag="J8R83_000367"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAZ9573529.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            53759..55057
                     /gene="eno"
                     /locus_tag="J8R83_000368"
     CDS             53759..55057
                     /gene="eno"
                     /locus_tag="J8R83_000368"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAZ9573530.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        18305 a         9607 c        11686 g        15599 t
ORIGIN      
        1 ataccgaggg tcagctgatt gaacaccgtt ttatcgagag gttgtgaaaa agtcgcttag
       61 tttcgagtag taagaaaaat tttgtgaaaa tggctttcca catttttgca taaatttgac
      121 ttaataccga gaaaatggct tttgaacaca gtttattcaa aaaaagggac tttgacacta
      181 cttttgtcaa agtcccatcg gttttttatc tatttttatt acaatcattt cttccagagt
      241 agtgacatct ggaatggctg aaatgtaaac agattatttg cctgtatcaa tgtcgaagag
      301 taatataaaa agtgtaaacg ctatcatatt gttcatcatt caaattttat agagagaagg
      361 cattgagatg gaaaaaacat atcaagcagg tacaaatgaa ggaatagtag attttatcaa
      421 tatggaagat ttagaaatcg cggcttcaca agtgattcca gctggtggtt atggttacat
      481 cagcagtggt gctggcgact tatttactta tcaagaaaat gaacgggcat tcaatcatcg
      541 tttgattatt cctcatgtat taagagatgt agaattaccc gatacaacta cacattttga
      601 cgaagaaatg ctgactgcac caatcatcat ggcaccagtt gctgctcatg gattagctca
      661 tgtgaaggcg gagaaagctt ctgcaaaagg tgtagcagat tttgggacga tctatacagc
      721 aagttcttac gcttcttgta ctttagaaga gataagagaa gcaggcgggg agaaagcacc
      781 gcaatggttt caattttata tgagcaaaga taatggaatc aatttggata ttcttgaagt
      841 ggccaagcgt aatggagcaa aagcaatcgt attgacagcg gatgcaacag ttggcggaaa
      901 ccgtgaaaca gaccgcagaa acgggtttac cttcccgctg ccaatgccga tcgttcaggc
      961 ttatcaatca ggagtaggcc aaacgatgga tgctgtatat aaatcttcca aacaaaaact
     1021 tagtccaaaa gatgtagaat ttatcgctgc tcattctgat ttgccagtct acgtgaaagg
     1081 tgttcaatca gaagaagatg tctatcgatc attagaatct ggtgctggtg gaatttgggt
     1141 atctaaccat ggtggccgtc aattagatgg ggggcctgct gcgtttgatt cgttgcaata
     1201 tgtggcagaa gcagtagata aacgtgtacc aatcgtgttt gacagcggtg tacgacgtgg
     1261 acaacatgtt ttcaaagcaa tcgcatcagg tgccgatctt gttgctattg gcagacccgt
     1321 tatttatgga ttgtctttag gaggaagtac aggagtccat caagtgtttg atttctttaa
     1381 aacagaattg gaaatggtca tgcaattagc tggaacacaa acagtagaag atatcaaaaa
     1441 aataaaattg cgtgagaatc gttttattta agaaataaat gacgaaaaaa ataggagtgc
     1501 ggcagatgat gccgtactcc tatttttata gttcaaggat gtcactaata gaataatttg
     1561 aaacgaaaaa ataaaattga aatatttttt catacttaat aaaaaaggaa gaatattcat
     1621 gtaaacgatt ttattgtttt tttctctttt atacaaaaag ggtcataatt tcaagtaagc
     1681 ggatgaattc atgaggattt tttgcatact gtctctacta tacttaggtc actaagaaaa
     1741 aggagtgatt tattatgaaa aagaacatga ttgggacatt attactttca acacttcttc
     1801 taggcggctt ggcaacacca gcttttgctg agggtcaagc gacttcaaaa ggagatatta
     1861 cctttactga accaacaaat accgttgagc ctcttaaccc tactgatcct tcaaaaccag
     1921 tagagccagc agatccggaa aatccagcaa ctggccagac aggttcttta acattggatg
     1981 tagttcctga attgccattt ggtacacacg agattgaaag cggaacaaaa acgtatcaag
     2041 tagacgcttc aaaaaacgat acaccttatc tccaagtatc agatcgtcga ggtgtaggtg
     2101 cagatggcca agcacaaggg tggaacgtga cagtttcggt ttcagatttt gtaaacggtt
     2161 cacaagtttt gcaaggcgct gaattagatt ttggaacatc cactgttaaa agtacgtcag
     2221 ataacgaatc cactggacca actagtcaaa ctgtaactgg gttgagtaaa gcaagtgcag
     2281 cgacaccaat atttacagca gcaaaagatc aaggtctggg aacatggctt tctgtttatg
     2341 atccagcaaa tatcacactg aaagtgccga aagcagcagc tggaacattc acggctgatt
     2401 tgacttggaa cctcgtggct ggcccagtag catagagtat gaaataaatt caacaaactg
     2461 cggtgaaaat actataggtg aaggattttt taccgcagtt gttgttgaaa ggatgtggtg
     2521 gacaatgaat caaagtaaac gactgtttgt ttcgtttttt tctattttaa gtctattttt
     2581 catttttccg tcaatcagcc aagcaaagga ttcagcagga gactttggaa tcaaaccggt
     2641 atttccagag aaccaaatag ataaagcaat cggttatttt gatttattag tggcaccgga
     2701 acaaaatcag acactagaag taattatcag caattcttca gatgaagaac gaacatttga
     2761 ggtctctgtc aatccggcgg taacgagtga tggtggaacg atcgattata gtcaaaaaaa
     2821 cccaacgtta gatgagacat tgccgtttga tgtccgtgac gttttgctca ttgcgaaaaa
     2881 ggaaatcaat gtatcagcac atgcagaaac aactatacct atagaagtga aaatcccagc
     2941 aaaaagcttt aagggacgtg tattagcggg tattcatgtt tcacctaaag aagaagctga
     3001 aacagaaaat gctacagaag gagcacaaat caaaaatcgt attgcttata atctcgcagt
     3061 cgttttacaa gaaagtcaag agacgataga accggatctg aaacttttat caggagattt
     3121 ggacgaggtc aacgcaaagc caactgttca gcttcgtttc caaaatcctc agcctaggat
     3181 tatcagcaat ttgatattta cgagcaagat cttttatgaa aatcagcttt atattgaaaa
     3241 tacgtctaat gaatttttag ttgcaccaaa ttcgaatttt cacttgaatc ttgatttagc
     3301 tggtgataaa gcaaaagccg gcgattaccg cgcagaaatc atagcaaaat caggcgacag
     3361 taatgaatgg cgatttacac aaaactttac gatcaaaaaa gaaaaagcac aaaaagtaaa
     3421 tgaaaattcc gtttttgcag tacaagaaca atctttccca tggctttatg caggattggt
     3481 tgctgcagtt ctagtgttat ggttgatttt gctgtttttg tgggtccaca agaaaaagaa
     3541 aaaaggagaa acaacatgat gaggtgattt cgttgaaaac atcgatctta ttgggaggga
     3601 ttattgcaag tttgctgttc ttcagctggc aagagccagt ccaagcagat accaaaagtt
     3661 caggtacgat tacattttat gatctaagtc cagttccgca tccaagtggt tcagtcaatg
     3721 gcgcatcaaa acagcagaca cagctaccga tttataaaga atctaatcaa catggcgtat
     3781 tcccggagac gaatgaagaa aagatccgtt ttctttattt gatcattggt atagaattat
     3841 ggcttcttgc gtggttgttg ttatggagaa gaaaggaaaa ggaggatgaa catgttgcta
     3901 caaaataaat tttcattttt tcgctccttc ttttttactt cgctttttgt tttaagtata
     3961 tttatctttt caccttcggc agaagctgtt ggagcaacgc ctcctgccat ttcttatgat
     4021 ccatacacgt atgaaaatat cgtacctcca aatggtggac gtagtgcagt caatggcggg
     4081 aagcttgtcc aactaactgg ggctaaccaa ttgcctaaat tgactgctac ttatttgaac
     4141 gatggttcaa atgatccttg gaaaggtggc acggtccgtt ttcattggga aagccatgtg
     4201 aaactaacaa atgtacttga tttggtgaat atcactgcac aaggatttgc atttgtggcg
     4261 atcatcaatt tgccggaaca tgtatcaagc agtgatgtat taaaagcaat tgactggaac
     4321 aacgcctact tgtatattgc cggtgccccc atcaaggtta ctagcggtag tttattatca
     4381 gcaggaagcc ataccttgcg ttttgggatg gggtcgtggg atacaaatac tctattggca
     4441 gatattattg ctattattac gcgaggcgaa ttcaacgtgg acgatatccc gcttcaattt
     4501 gatgttacag ctaatgtcgc gaagatgaca gaaaacggag ataaatatga tacgagtcca
     4561 aacaaaattt tgaccaaggg taaattacaa ccttctatgt ctaaaaaggc cgttttttct
     4621 gttgattttt atgattcgaa taatattatc caagatcgta tgttcaattc gattttagct
     4681 ccagctgcag gtagatttta tcctaaatta actggcggaa acttgaatcc aggagcatat
     4741 gcattttctg caagtgcaga gataaatacg tggaatagtt acatctcaac aagtgattca
     4801 acaggaaaat ataatacatt tgctgatacc acagaatacg tggatggaaa taaccagaac
     4861 cttccaggct ctaccaatag tcggacattg acgatggggc tgactgaagg acgttttgat
     4921 cagttgccat ttagtcgctt tgatcgcgta gtcaactatt ttacaggaaa aaacgttaca
     4981 caaggagcaa tactgactca tactccagca agcacaagtg gattgaatca gacagccaat
     5041 atcgtgtaca gtgggaaaga tgcgcaaggc ggattgcttt ctcctgttgc tttaaaggta
     5101 ttggagcagt acaagctaga cggaacggtt ttaccaacaa acttaacagc cgatagtcag
     5161 tggggaaagc tcctttcttc tgcatcgtac caagtcacgg ccaattggtc agcaactgaa
     5221 ctaaaaaagg gttcgatcca ttacaggctt tattcgaaag gaacccaaaa attagcgaca
     5281 ggatggacag atcaactttt ccaaacgatc caatcaaata acgggggtgt aaatacagct
     5341 acttctacac tacctgcatt ggcttcaggg caatattatt ttgattatcg cttggtggac
     5401 gatgtactta ctaacatgta tccgtctttt gcgtacaaat ggcagtctga acaagctgga
     5461 atcaccactc ttcctcaaat aacagtggct aattttccat ctgtgagtgc agatagtcag
     5521 ctaaaaaacc ttagcagaca acctgagaca ggagatcccc tgtctgctct atcaggagat
     5581 acgattcaag aaaatgtgac attcacgtta acaaaatctg gggatgcgat aaccgacaaa
     5641 aaaatcacga tctcacttcc tgaaaatact acttatatca atggttcctt aaaattaaat
     5701 ggtacaacta tcgcagatac cggcattcaa caaggagttt ctgtcccagc agatctattg
     5761 agcaaaatag gagataccat tcatcttact tacaactatc aattaaatac tgtagatact
     5821 tctgtacaat ccgtcagcat actgacaaag gcagctgtac tttccagcaa tattacatta
     5881 gcagatggtg ctaagcttcc taacccagtt gtccaaacat ctgctaaaac aattcttgtc
     5941 cccaaacaag aattaacatt agttaatgta ccagatgatt ttacatttgg taacgatctc
     6001 cccaaaccgt tgaagacaag ttattatgaa gcaaaaggcg atttttcttt tgatgtgcgg
     6061 gatactcggc ttccaagcac gtctccttgg caactgacag ggacattgac ttctttattt
     6121 aagaatgatc aaggtcaaga attaagcgga acaaaattat acttcaatca ttctggatca
     6181 aaacaattga ttcagcaagg tcaaaacacg ttgatttatg agagtgatgg aacagctaaa
     6241 ggagaggttc tcgttgactt tcccgatacc gatggtttac tcttagaggt aaatagcagt
     6301 acgaatgctc aacctggcgc aacgtatcaa ggcatggtca catgggaact gacagctggg
     6361 ccaaccagct aagtgattag aatttgtatg gatctgtgat aactgtcaca gatcctcttt
     6421 ttcaaggatg agaaggaaac ttctgctgtt aaaatcagaa atgcttggag gagtggactt
     6481 ggaacttttc agtttgcttg aaaaaaatga acaacggcaa atcaaacttt tccaactttt
     6541 attagaggaa aaaggagaga tttccgttaa taacgtactt acccgcttat cagttgatcg
     6601 ggctaccttg aaagaagatc tgttttattt acaagctaac ttggaaaata tcaaacaatt
     6661 ggaaattgtt atccaagaag ggaatatttt attaatcaga catggaaata tagcagcagt
     6721 cgatgtttat tatcattgct acttgcgcta ttctacaaaa tatcagatac ttctttatct
     6781 gttggaaaat ggctcatttg atcggcagaa acttgtcatg gaacttaata tcagttcggc
     6841 tactttgtct cgcagagtga aggaattaaa tgattcttta aatgagtttc atctgaaaat
     6901 aaaaagcggg cggctgaccg gtccagaaag tcaaatttgt tatttttatt tccaattatt
     6961 ttggtttgga cgtccttatc ttgaaaacaa aaaagaatac agtgatttat caggaaacac
     7021 ttttttagat ctgctgcaaa aagagtttag ttttactatt acagaagaag gacgattgaa
     7081 atttgaaata tggctttcca ttatgaagaa gcgaatgcgc tgtacgaaaa aatccaaacc
     7141 agattatagc aatcttcctg ttggattgtt tcaaacgaca caatttttat tggacctcca
     7201 tacatttttg acccgttact tctttcaata tgcctttcct tggaatcaaa atgaaacgtt
     7261 ggttttttat cttttcatga tcagtaactt tacattagat acacataact cgcatgtcca
     7321 ggagtttttg ataagcgaaa aatacaaaga cgacgtagta gctcaattga atcgaacgtt
     7381 taaacaatcg atagaagaat atttctcttt ttatgttttt ccagaagaga tttcgcaaaa
     7441 gattgcgttg acagtgatgc aaaatcacgc tcattttgcc tattttagag gatggatgaa
     7501 tatttttggc caagaaggat taaaacagcg gttaactgaa gtagaagata aacaattcct
     7561 ggttttatgt gaaagattgg tcagacaaac atttgctatt gttgatttta ctgaagtaga
     7621 cgaggaaaat gcccgctttg aattatttgc tcgctatgca tctattttgc ggacgctgat
     7681 caagcagtta gaattacgtc tgcaaattgc ttatgatctt ccttatgaaa ggctaatggc
     7741 ggatatcgtg aaagaaatca tccaggaaca attgctgaat acgatcaaat atgatttagt
     7801 cgaatacgag aaagaaaagc agtatgatat cattttgact agccaattga aagagtaccc
     7861 gtcacagaag tccgctaaag tttttgtatt cactagcaac gaatataatt atgatttccc
     7921 ctatttgaac caatttttaa aagaatgtta tttagaaaaa ttgaatttaa ggatgaataa
     7981 aacatgaaaa tcgtgatcat tggtgcttcc catgcaggca tcacagctgc cctaaatcta
     8041 agaaaacttc aaccgaaagc agaagtttta ctgatcgatg aagatcataa agatggacta
     8101 ggctatgttt caaatggaat caacctttat ttaaaaggaa agatacgtag tttagctgaa
     8161 gttgcccata acatgcggac tcttcaagaa agtggggcaa aactgatcac cgaatggaga
     8221 gtaactgaac ttgatccaga caaacatcag ctcatcctcg catccaaaga aggaaaaaac
     8281 gagaccataa cctatgataa attaatcgta gcaacaggtt cctctcctgt caccttgtat
     8341 aaacaaattg aagctgaaaa tgtctacacc tataaaaatc tagtgcaatc taagcaagta
     8401 cttgccgctt taaaagaagc aaaagaagta gtgatcttcg gtgctggtta tattggattg
     8461 gaattagcag atgctttgag aaataaagga tacattattc atctagttga ttatatgccg
     8521 aatgttttaa caagatattt cgataaggat atgatcaaca gttttcaaaa tcagctgcaa
     8581 actaagcaaa tcaattttta tccaaatgaa ttcttgatcg attggaaaaa atcagaagag
     8641 aaagtagtat ccgtacaact tctatctcaa gcaataaagg cagatatggt cattttttct
     8701 gcccaaactc gtcctaatac gacattgtta aaagaaaaag tggctttgta tgaggatgag
     8761 actgtgatag tcaatgaata tctgcagaca agtgatccgg acatctatgc gattggagat
     8821 atcgtcccag tcagttttga caaaaataaa cggcatctct ttttaccttt agttactcga
     8881 gctgtacata tggcaagagc agtagcgcta actttgagtg gtcagccaac cgcttacgac
     8941 ctcagacaaa agataacagc agcagtcatt atagactact ttttaggaac tgtagggctg
     9001 acagaagatg aagcgccatt cttggaacaa aataccggtt cgtgttcagg agaatttgat
     9061 ctatttccac aatacgatga agaaaacaaa acagtaaatg caaagctgat ctaccatccg
     9121 gatacattag aaataattgg cggacagctg ataagccaag aattcttatt atcagatttg
     9181 aacctgcttg cggatatcgt gaaacacaaa actacgattc cacagctagc agttgaggat
     9241 tttggatttc tgtctgaaca cacctctcgt tttcactacc tcaatgagtt agcttttaaa
     9301 gtactagcta agagagcaaa tagcaataga gtagataaaa gactgtgaga aatatcacgg
     9361 tcttttattg tgtggggata taataaatat taatcaatcg agaataaaaa attcatataa
     9421 tgaaatagcg gaagaatttt ttgagcataa tattcgccaa aaatttatca agtgataaaa
     9481 ttgttgtata aaatgattat ttcaggagga ggagttaaat gtttttagca ttaaatgaaa
     9541 ttatgcattc aaagttacgt tatgcgttag ttgcaggggt gatgtttttg atcgcctacc
     9601 tggtattttt tttgactggg ttagcttatg gcttagctca agataatcga acagcagtcg
     9661 acaagtggga ggcagattcg attgtgcttt cgaaagatgc aaattcaaat ctagggatgt
     9721 ccatgattac taagaagata gcagaagaag tcgaaggtgg gaaagtggcg tatcttgccc
     9781 agacacctgg agtcgtgact agtaaagaca gtacagaaga aggaaaaatc aatgttagct
     9841 tcttcggtat cgataaaaat caattcatca tgcccaatct tgttgaagga aaagcttttg
     9901 ataacgatga tgaggcagta ggcgatatta gtttgaaaga agaatatggt ctagccgtag
     9961 gagatacagt taagttatct ggtagtgaca agacgtttaa actaactggc tttacggatc
    10021 atgccaaatt caatgtctca ccagttctct atacaaccat caatgcttac caagagatcc
    10081 gcttcgaaaa agaagataca agtgaaaatg cacggattaa cgcaatagtt gtcagaggta
    10141 aaatcagtaa tttacctgaa gatttagaac agatcaaaat ttctaaattc atcaatgaat
    10201 tacctggata taatgcgcaa gtattgactt ttggatttat gatcggattt ttgatcgtta
    10261 ttgcggctat tgtgatcggg attttcattt atgtactgac gatgcaaaag attaatatct
    10321 ttggtgtaat gaaagcacaa gggatcacag gaggatttat tgcgcgttct gtagtggcac
    10381 aaacattcat tttatcattt gttggtattc ttcttggtct attaggaaca gtgggaacat
    10441 cccttgttct acctgatgcg gttccattcc aaagcaattg gctgtttttt ggcgtcatta
    10501 gcttgttgat gctggtagta gctgtgttag gcgcactatt ttctgttcgg acaatcgtaa
    10561 aaatcgatcc gttgaaggca attggataag aaggaggaag agcatgaaag caatagaatt
    10621 taaagaagta gaaaaaagtt tccaagatgg cgaccaagta gttaaagcat tgaaagaaac
    10681 aaccatgagt atcgataaag gggaatttgt tgcaatcatc ggtccttctg gttcaggtaa
    10741 aagtactttt ttgactttgg caggcggatt gcagacgcct agcagtggct ctgtatttat
    10801 caatgatcaa gaattcagta atcaaaaaga aagtgaacgc gttaaactac gttttaaaga
    10861 aattggcttt attttgcaag cttccaatct ggttcctttt ctgacagtaa aaaagcagtt
    10921 attattagta gataagatca aacatgaaca tcgtcaaaaa gaagcaaaag aattatttga
    10981 gcagcttggc gtggataagt tgatcaacaa gtatccagaa gaactatctg gtggagaacg
    11041 gcaaagggtc gcaatcgctc gtgcattgta caatgatccg tccattattc tagcagatga
    11101 accaactgct agtttggatt cagaaaaggc acgagaagta gtcgatatct tggcaaaaga
    11161 atcaaaagac aaaaataaag caacgatcat ggttactcac gatacacggc tgattgacaa
    11221 atgcgataga atatttatga tggaagatgg tgtattgaaa gaaaaagaat aaccaaaaag
    11281 caggtggaaa aatggtccat cgatacaaca aagatacaca gcaaaaaatt ttgaaagaag
    11341 cgactgactt gtttatgtcc aagggatatc tcggcacttc aacaagagag atcgcacaaa
    11401 aagttgggat cacccaaccc aatctctatc attatttcgg tgataaagaa aaactatata
    11461 cggcagtttt agaaaaccac ttaaaagatg ttggaaaagc tttgagagaa atcgttcaaa
    11521 caagcgaaac gggatttcaa gtaaccttga caaaaatggc gcagtttttg attgagacac
    11581 atctggtcga tttgtttctg atgcttcacg atcttgaaag caatctttca aaggaaacaa
    11641 gagatcatct tttctttcta tggaagaaaa attatcgtga accttttgaa gaaatctttt
    11701 cagcaaacca atctgtgcta agaaatggga tttcaaaaga aatcgcagca aggcattttt
    11761 tcttagtgtt agcaccttac atcactcggt cgaaaagacc tgtggaagaa ccgctaaatg
    11821 tggcgcaatt gatcgattta tatttgaatg gtgtattagg agaagcgtaa agctgttata
    11881 tagggagaaa aatagttagg tgaagaagca agatatgacg aagatcgtta tatcttgttt
    11941 tttttatata ggtagttttt cataaataca aatttgttat tctctcatga ttatcagggt
    12001 atatttttat ttattatgtc ggtgttccag gaagtgtttt aatttaataa cgaagaaatt
    12061 aattgtttgt agaatgaagg aaactattta ttgggtagat gaatcaccac gaatagtcaa
    12121 aaggagattt caggatatgc caaaaatgaa aaaaatcatt ttagcagtaa tgttattttc
    12181 tacggttata tcttttacag cccctttttt gcgtacttaa gctgatttta agttttgacc
    12241 cttagtctgg atctacgagg tgagagtcaa gaatgaaaaa aataattgga gcttttgtat
    12301 ttgcaatcat tatcattatt atctgttttc aaatagatgt ttttggtcaa aaaaagatag
    12361 ttggacaaac ggtcagcagt acgaacagta cggttacaaa gacaaaggaa tcatttgatg
    12421 atacagaaca agagacatta atcaaaatcg gaaaaaatga ccgtacacta tatacagatg
    12481 actcgctaac taccccactt gcaactataa acggcggaga gctggcggag tttctttctg
    12541 aaacaaaaaa tgcttatcag atcaagacaa atgatggcta tactggatat ttagccctcg
    12601 aagatggaac caaagtcaca aagaatatac aaacaaaacc ggaagagcta tctgatgcag
    12661 tgattgtatt agatcctggg catggcggaa atgatactgg ggcattaagc aatgatgaac
    12721 aaacagaaga aaaagatata acattaagta cagccataaa agtaaaaaag gcgctagagg
    12781 atgctggagc aacggtttat ttgacccata ctacagatga attagtacag cttggagata
    12841 tatgcgacta cagtgaagaa aaaaaggcag atgtctttat cagtttacac gcagactcta
    12901 cggaatatgc gaatgaagca actggaatca cgacatatta ttactatgga caagaggaaa
    12961 cattagcaca gacaattgct gactccttca ctgatctgcc tctggattca agaggaatct
    13021 ccactgggaa ctatcaagtt cttcgagaaa atcttcaacc ttctatttta atcgagatgg
    13081 gttatatgaa taatgatagt gatttaaagg aattagtaac agacagttat cagcagcaga
    13141 ttgctgcaag tttgacacaa gcattgacca cttattttca gtaataaata agcccagcca
    13201 aacaaaaata gctcctcata tttttcgttt ggccgggctt attatcgcag atgcaagctt
    13261 ttgaacaccg tttaaggaag aggttgtgag cctgccgttt aactccgcgt cacaaggagc
    13321 aatttcaaaa aacagcttct catgtttgat gactattgtg acttgtgacc gaggagttgg
    13381 catgagaaca ccgtttattc ggaacaaggg actgtgacat gacttttgtc acagttccat
    13441 tattttttta gcagcttcaa agctttttct gtattggcaa aatgaagttt ggcatatttt
    13501 tcaagcatag gcatgccgcc tttctccaat agttttgccg ctacttggtc agatttcgtt
    13561 ccagctcctg atggaagggt gattccagct tcagctgatg ctttgtgtaa ctcttccaaa
    13621 aagctggcac gactgatgat agaagcagca gcaacagcta aatgatattg ttctccttta
    13681 gtaacgaagt acagtttttc ttgtaattga tttttttcta aacgcgcata ttttttaaaa
    13741 tttgcttccg gcgtaaactg atcgatcaaa atcgcttctg gtttttctgg ctcgattttt
    13801 tttagcagca aatggatcgc ttgattgtgc aaagcgactt tcatccgaac ggcattgtat
    13861 tttggttgga tctcattgta tttttctgga gataagacaa gcagtttata ggggatggtt
    13921 ttttttaaga tgtcagcaag ctggatgatt tggctatctt ttaactcttt tgaatctcta
    13981 acaccaagtt tacgtaattc tgcaagctga tcacgtttca cataagcagc acatactgtt
    14041 agcggaccaa aatagctgcc atttccgacc tcatcactac ctaaaacgga taattgactg
    14101 atattttttg gcaaagaaga ggctgttttt gctggcttgg cttgtttatc ctgtgcctcc
    14161 ccccatttat cagcttctat tgctgcattc gtaccttgaa acatcacttt tccggatgta
    14221 taagcggtaa tggtcgtccc gtcttttttt gcagcaaagc tagtataagg aatctgttta
    14281 tttaacaaat aagagcgata gtatgctttc atttgactaa gttggtcgtt tgttgctttg
    14341 ataatgacgt tgctcataaa attctcctcg tttttataca taaaactata ccgcaactca
    14401 cgacttttcg ttttctaaga gattgcgaga catagcattt ttttaaagtt tatcatataa
    14461 tagttaagta tgtgaaaaat atttgtggag aacggtgaaa gaaccaactt catggtacac
    14521 taaataaaac tttcatcaaa taggaggaaa tgattcgtat ggcgcacgaa aaaacacgct
    14581 acaaagcagt gattgccaac caaacatata ctattatcgg acgggaaacc aagcatcata
    14641 tggatatcgt aacgaagctg atcaatgaac agttagcaga attgaaacaa ttatcaccac
    14701 aaatggataa tgaacaagca gcaatcttga tggctgtcaa tgcgctttcg gatcaattga
    14761 agaaacaaga aagaatcttg gagctggaag aagaaacagc agaattaaag aaaaaaatga
    14821 tcaaatttac agagcttgaa aatcgtgtga aacgcattga agcaatcgag aacgaagctc
    14881 gggaagtatt gaaagaaaat ggtcaagcag atcataccat taaaaatcat gtggaagcac
    14941 aacagatttt aaacgagaaa cgaaaaggac aaattaaaca aaaatcttct aattaagatc
    15001 cttttatcaa aataagaaaa atttaaaaaa gttagaagag aaaggaacgt agcatgctga
    15061 gtttgctgat tttattttta ttgctaattg cgtttttttc tggagcacgt cgcgggtttg
    15121 ctttgcaaat catattcgcg attggatatg tattgtcatt tattgctgcc cagcattttt
    15181 acaaaccatt agcaagtcat ttggaattat acattccata cccagctgtc accccaacat
    15241 caaagttagc attttttgat caggtatttg cttttcacct agatgaagct ttttatgcag
    15301 gaactgcttt tctgattatt ttgctaattg gctggctgct tacccgattt gtgggggttt
    15361 ttgtccatgg attgacgtat gtgccgatct tgagacaggt agactggatt gcaggaggca
    15421 tcctgtcact aatcatggct tacgttacta tatttttgat tttgcagtta cttgcctttg
    15481 ttccattaga tgtggtccaa aatcaattcg gcgagcatag tttcgctcgt tttatcgttg
    15541 agagaacgcc atttcttacc aacaagatgt atgagctttg ggtaacgaat attttgaatt
    15601 aaggaaaata gtgctggaaa atatttcgtt ttttgtacag agtagtttat ttaagaaggc
    15661 tgcgtagcgt atgtccggca cagctctttt ttcatagtga aagataaggt gataaaatga
    15721 ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa acagatggtc agacaatttg
    15781 tagtgactgc acaaggaaaa gaagaactgg cagaattggt accagtgagt gagaaacaaa
    15841 cgatcacaaa ctggcttcaa gaaactgagg atggattgaa agtgcaacgt ctgcgaggcg
    15901 ggatccctat acctaaactt gaaaatatcc gtccccatat gaaacggatc gagatcggag
    15961 cagacttgaa tggagtggag cttgcacaag tttccagagt attgtctacg acaagcgaat
    16021 tgaatcgttt cattgatgat ctttctgaca gtgaaatcga atttgcacgt ttgtatatgt
    16081 gggcagatca gttagtcacg atccctgttt tgagccgccg tttaaaggaa gcaatcgatg
    16141 aagacggacg cgtgactgat gacgcttctc ctgagttaaa gagcataaga cagaacattc
    16201 ggcgaagtga acaagctgtt cgtgaacagt tagatgggat cgtccgtggg aaaaatgcaa
    16261 agtatttaag tgatgcgatc atcaccatgc gaaatgaccg ctacgttatc ccagtcaaac
    16321 aagaataccg cggtgtattt ggcggtgtag tccacgatca aagtgcttca ggacagactt
    16381 tatttattga accaaaacaa gtggtggatt tgaataatcg tttgcgtcaa taccaaatcg
    16441 ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc tgctgaactt gttccccatc
    16501 gtcaagaaat catccacaat gcttatgtga ttggtaaaat ggatctgatg aatgcaaaag
    16561 cacgatttgg taaagaagta aaagccatcg tgccgggaat cagtgaagac aatcatgtcg
    16621 tcttgaaaca agcaagacat ccactgatcg atcaggaaaa agtagtttct aatgacatca
    16681 caatcggaaa agactatcaa gccatcgtca ttacaggacc taacacaggt gggaaaacga
    16741 tcacgttgaa gactttaggt ctgttacaac tgatggggca agcaggatta ccgattcctg
    16801 caggtgaaga aagtcaaatc ggtatttttg aggaagtatt tgcggatata ggagacgaac
    16861 agtcgattga gcaaagtcta tcgacctttt cttctcatat gacgaacact gtagatattt
    16921 tatcaaaagt caatgaaaaa agtctggtat tatttgacga gctcggtgca ggaacagatc
    16981 cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga tcttggtaaa aagtctgctt
    17041 atgtgatggc aacaacgcat tatcctgaat tgaaagttta tggatacaat cgggcaaata
    17101 cgattaatgc cagcatggag ttcgatgtgg atacactaag tccaacgtat cgtttgctga
    17161 ttggcgttcc tggacgaagc aatgcgtttg aaatctctag ccgattaggt cttgatacag
    17221 aagttattga tgaagcgaag cagttgatga atgatgagag ccaagattta aacgaaatga
    17281 tcacagattt agagaatcgc cggaaaatgg cagagaccga atatctggaa atgcgtcatt
    17341 ttgtttctga ggcacaagaa cttcacgatg atttgaaaga agcttacagc tatttctttg
    17401 aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc aaacgaagtc gtgtcagagg
    17461 cggaagaaaa agcagaaaaa atcattgctg atattcgtaa aatgcaacag cagattgggc
    17521 aaggaaatgt gaaagagcat cagttgatcg atgcaaagac ccaattagca aatctacatc
    17581 aagaagaaac tttgaagaaa aataaagtat tgaagaaggc gaaagaacaa aaaacgttga
    17641 aaccgggaga cgaagtgttg gttacgactt acggccaaag agggacgctt ttacgtaaaa
    17701 acgggaatca gtggcaagta gaaatcggta tattaaaaat gaatgtgtcc gaagacgagc
    17761 tgacgcctgt tgctcctcaa aaagagccga cacaacgagt tatccatgct gtacgatctg
    17821 aatctagtag tcacgtgccg aatcaattgg accttcgagg aaaacgatac gaagaagcgc
    17881 taagtgaggt agatcaatat ttggattctg ccattctagc tggttatcct caagtgacta
    17941 ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat tactgattat cttaaaaacc
    18001 atcggagcgt caaaagcttt gagtttgcac cggcaaacca aggcggaaat ggtgcgacaa
    18061 ttgttaaatt taagtaaagc ttactaaagg taagcagatg gttcgctatc caagtataga
    18121 aatgctatac taatcataga ttttaaaaat ggaggtcttt gatatgtcac aagtaattac
    18181 agataagaca tttaatgaag aaacagataa aggacttgta ttgattgatt tttgggcaac
    18241 ttggtgtggt ccatgtcgta tgcaagcacc gattttggat cagttggaac aagaatatga
    18301 tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa aatccagaaa ctcctcaaca
    18361 attcggtatc atgagcattc caacattaat gttgaaaaaa gatggtcaag tagtagaaaa
    18421 agctgttggt gttcattcaa aagaacaact acgtcaaatg atcgatcaat atttataaaa
    18481 acttacagca aaaataagct gagggtggga ctgaatccag ttccgtcctc ggtttttttg
    18541 cggttgagtt aaggttattc aaattaatat tttttgagta taattacgtt gtcaggctgg
    18601 attgtttttt tgacagacat gctataataa ctttaattga atatgaaggg gagtaccaga
    18661 tgaacgaacg aatcaaaaac aaattagctt tacttcctga tcagcccggc tgttacttga
    18721 tgaaagataa aaatggaacg atcatttatg tcggcaaagc caaaatatta aaaaatcgtg
    18781 tccgctcata ttttactggc agccataata cgaaaacgga acggcttgtt agtgaaatcg
    18841 aagactttga atacatcgtt acagaatcga atatcgaagc attgctctta gagatcaatc
    18901 tgataaagaa aaatgatcct aaatacaaca ttatgttaaa ggatgataaa acctatcctt
    18961 tccttaagat aacgaatgaa aaatatcccc gtttggtgat tactcgtaaa gtactaaaag
    19021 acaaagcact gtattttgga ccatatcccg atgtcggtgc ggcgaatgag acaaagaaga
    19081 tcctcgatcg attatttcct ctgagaaaat gcaaacctag tcagacgaag gagccttgtc
    19141 tttactatca tttgggacaa tgtctgtgtc cttattattt cgacgtagat ccgaaagtct
    19201 atacgaaaat cgttgatgaa gtgaaaaagt ttttaaacgg aggacacgaa aaaatcgagt
    19261 cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat ggagtttgaa aaagctgcag
    19321 aataccgaga ccagatccgt gccattgaga caatcatgac tcgccaaaaa atgacaaata
    19381 ctgatttact ggatcgagat gtatttggtt atgcgattga caaaggatgg atgtgtgtcc
    19441 aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga tgtttcaatg tttcctttct
    19501 ataacgaagc agaagaagat ttcttgactt acctcggtca gttttatcag gaaaatgagc
    19561 atttcattcc taaagaagtc ttgattcctg atacgatcga caagcccagt gtagaagctt
    19621 tgttagctac gaaagtgctg caaccaaaac gaggagaaaa gaaaaaatta gttgaattgg
    19681 cgaataagaa tgcctcagtt gctttgaatg aacggtttga tctgattgcc agaaaacagg
    19741 aacggacgat cggagcagtt gaacgtttag gaaacgcgat gaatatcccg accccaatac
    19801 gtatcgagtc ttttgataac tctaatatca tggggacgaa tcctgtggct gcgatggtcg
    19861 tattcattga tggaaaaccg gcaagaaaag aatatcggaa atataaaata aaaacagtca
    19921 acggaccgga tgattatgca tcaatgagag aagtcatcta tcgcagatat tcacgagtga
    19981 ttcgcgaagg gttgccttta cctgatttga tcttgatcga tggaggaaaa ggacaagtag
    20041 atgtggcaaa agatgtctta gaaaatcaat taggaatcga tattcctatt gctggcatgg
    20101 caaaaaacga taaacataaa acaaatgagt tgctattcgg tatagatttg gctgtagtac
    20161 cgcttgagcg aaattcacca gagtttttct tactccagcg aatccaagat gaagtccatc
    20221 gattcgcaat cactttccat cggcagctac gcagtaaaaa cagttttgct tcccgattag
    20281 atgaaattga agggttagga ccaaaacgaa aaaaaatgct gcttaaagag ttcaaatcgt
    20341 tgaaaaatat cacagcagcc acgacagaag aattacaaga aatcggactg ccgaaaaatg
    20401 tcgcacaaaa cgtatttgat aaattacatc aggaatgagg aaagggcact ttacaaagaa
    20461 agtaaagtgt cctatcattt tatgtacaac aaaaagagcg tttacgtttt gttggtaaat
    20521 aataaatcgc ttacgtctgg tgtctaagga tatatgtgat ttcttgaaga aggagtgaag
    20581 aaatgttaga agtcaaggat cttgttaaaa cttttgggaa ctacacagct gtcgatcatg
    20641 tctctttcca aatccccgat ggaaaaatca tggggctaat tggccaaaac ggggctggga
    20701 agacaacgac ttttcgtttg atcttggatt ttttgacaca agaccaagga gaagtgttat
    20761 ggaatggcca tcatcttggg gagaaagatt atgatgtcat cggttatctt ccggaggaac
    20821 ggggacttta tccgaaagta acgattcaag accaactgct ttattttgca gaacttagag
    20881 ggaaatcaag aaaagagatt gaaccaaaaa tcgatttttg gatggaaaaa tttcaggtaa
    20941 aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg aaatcagcaa aaagtccagc
    21001 tgatcgccac gttaatccat gaacctaaat tgatcatttt ggatgagcca ttcagcgggt
    21061 tagatccggt aaatgctgaa ttgctaaaag atggaatatt ggaattgaaa aaacatggtt
    21121 catgtgtcat tttttctagc cacaatatgg ataatgtaga aaaaatctgc gatcatttga
    21181 tcatgttgcg aaacggaaaa atggttttga atggaaaagt acatgagatt cgtgaatcat
    21241 ttggccgtac gaagttattc ttggaatctg gtttaagcca acaggaagta gaagaaatcg
    21301 aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt agagattacc ttagaagatc
    21361 ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt cggctacatt cctatgttta
    21421 accagcaacc gccaactttg gaagagattt tcaaattgaa agcaggtgaa atcgatgcgt
    21481 aagttttgga ttattaccaa agatgtctat ttaaaaaatg ttaagtcgat ttctttcttg
    21541 atcatgatat tagtcccttt tatcatgctg ggtatcattt atgtagcagg aaactttgct
    21601 caacaaaata gtgatgtcaa taaaatcggc gtattggctg ataatgagca aatcagtcag
    21661 caaatgagcc aagtcaaaac agatgatttt gagttcaaag cagttgattc tgaagaaaaa
    21721 gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt tagtagtctc aactgagaat
    21781 gataagataa atgggatgct ttatagcgaa aattcattag gacaaagtac acaactactg
    21841 atacaacaac aactgactgg cttgcaatcg atgcttcgag caagtcaatt aggcatttca
    21901 ccagaagaag tagctagctt gagccaacaa gcaagtttga ctcgacaaaa agtcaatttt
    21961 gattcaaaag gaaaaatgac agttggagaa gataactcga cagtccaata tgtcgtaagt
    22021 tatgtagcaa cgattgtctt gttcattatt attttgacgt atgcgcagat cattgcacaa
    22081 gagatcgctt ctgaaaaagg cacgcggatc atggaagtga tcctgtccag tacgactgca
    22141 caaaagcatt tttacggaaa actaacaggt gttttacttg ttgcattaac gcaaatggca
    22201 ttatacggta ttatttttgg tataggatac agtcaattca aagatatgga aatggtcaaa
    22261 aatatattag acggtatctc attggataac ttgattggac cattcttgtg gtattctctt
    22321 ctattcatga tctttggcat tttgattttt tctgttttag cagctttatg tggctctttg
    22381 gtcaacaaag cagaagatac agcaaaagca attttgccag tgacttatct atctctaggc
    22441 ggatatatgc ttggattgat actaggagct tcagatccaa acaatatcgt tattcggatc
    22501 acttcgtata ttccattctt atcttcatat attatgccgg ttcgcttagc aaatgagaca
    22561 gtcggtatgg gtggagcatt gatttccttg ttggtacttg tagccgtaac attcttattg
    22621 atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg tgtatagcga aggcggatta
    22681 tggagttcat tgaaacaatc gatttcaatt atgagaaatg aacgaaaaaa agcataaaat
    22741 atagaaaaat atagaaggaa gctggacatt tattgttccc agcttctttt ttgtatagac
    22801 ctatttctat ttttttatta tattggatat atatattcat tgaaaataga gcataacaac
    22861 tttataatgt tgagtatacc aatttttgga ggcgttttaa tggaccgcta tttagattta
    22921 ctttcagaga agttccctac aacggaagat gtcatcacgg aaatcatcaa tctcgaagca
    22981 attttgcagc ttccaaaagg aacagagtta tttttgagcg atatacatgg cgaatttcct
    23041 gcttttgatc atattctgcg tatcggttca ggaaatctta aagaaaagat caaagacctt
    23101 ttctctgaac aaatgacgga aacggagatc agccaattca ctatttttac ggcttatcca
    23161 gaatatgtgt tgacgactga ttggtacaaa aaacaagata aatcccagct gatccatcgt
    23221 ttgatcgatc ttttacggtt tacgacagtc aaatacactc gatcaaaagt tcgaaaagga
    23281 ttgccgaaag aatatagcta tatcattgag gaactcttgt atatcgatga tcgtatcaac
    23341 gggaaaaaag actatgtaaa aaaaatcatt gaacaacttg tcttgatgaa ggaagaagaa
    23401 aaatttttaa caaaacttgc gcagacgatc caaaaatctg tcatcgatca tttgcatatc
    23461 gtgggtgata tttttgatcg aggaactcaa gcagccaaag taatggatcg aatcatggat
    23521 ttttcctctg tagatatcca gtgggggaat catgatattt tgtggattgg tgcgtattgc
    23581 ggctctgagg catgtttatt gacgctttta cggattgccg cacgctacaa ctatttattt
    23641 gaattagaga aagaatatgg attaaattta cgtccattat tttcttttgc ccatcaaacc
    23701 tatcagaaga atccagtatt tacccctaaa aacaggaaag atctatctga aagagagcaa
    23761 gaagaattag aaaagatcca tcaagcactt tctatcctcc aattcaaatc agaacatcag
    23821 ttgttgaatc gacgacctga atttaaaatg gacgatcgta aattgttgga aaaaatcaac
    23881 tatgaggaat caacgatcgt tttagaaggt cagctctatg agttgaaagg gacttgtttt
    23941 caaacgatcc agccagatga tcctaaaaaa ttcttggaag aggaacaaaa agtgatcgat
    24001 agtttgatgt attcattcca gcactcgtta agaatgcaaa aacacatgac gtttttgatc
    24061 gaaaaagggg gaatgtatct cacgaacaat cagcatgtac tgttccatgg ctgtatacct
    24121 gtagatgaaa aggggcagct cttagcattt gaattagacc aatcttatcg cggaaaagaa
    24181 ctgctgggat tttttgaaaa acagataact gaaagcgcaa aagatttgac tgcaaatgaa
    24241 gatttggcga ccgatttgat ttggtatgcg tggagcgggc cattttcgcc tttattcggc
    24301 aagagtaaaa tggcaacttt tgagcgctat tttctcacag agcctcatac gcacgtcgaa
    24361 aaaagcaatc cctattatca cttgcgagat gaagagtggt tcagtgaaaa aattttggca
    24421 gaattcgatg caaaagaaga aggttcagca atcatcaatg gacacacgcc agtaaaagta
    24481 aaaaaaggag agtcaccgat caaagcaaac ggaaaagcat ttgttattga cggaggtcta
    24541 tccaaagctt atcaaaaaac aaccgggatt gctggctact cattactatg caattcttac
    24601 ggtttccaaa tcgtgacaca ttatccgttc ttgcctattg aacaacaatt tgcaaaaaaa
    24661 tctgatcaaa cgaatgtaaa aaaagtgatc gagcagcagc tcccacgcaa acttaatcgg
    24721 aatacgacaa aaggaatgga attacagcaa cagattactc aactccaaag gctgttggat
    24781 tatcgaaagg acgattgaga aaaatgctag ccaacattgc tcaatagact aaaaagcgac
    24841 tgcaacaaaa ggcgtgtcgc agtctccttc ggaattagct caaaaaacgg taaaatatta
    24901 gaagctattt ttctgtttat ttctctaata ctcaggtcag ggcgctgatt tcacgacctc
    24961 ttccttaaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat ccaacaaaca
    25021 tgagaagctg ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac
    25081 ctaatcagaa aaacgattaa aattcattca caaagaaatc gaataaacgc tgttcagatg
    25141 aatctacacg atgagaaagt tccggatgcc attggacacc aaggattttg tgcatattat
    25201 ctttactttg gactgcttca atgagtccat cgttggaaaa ggcgatggct tttaacaaag
    25261 gagaaagatc tttgactgcc tgatgatgat aggaattcac aaagtatgaa tcagggagaa
    25321 ggtcacttaa taaactgtcc gaaacgattt tgacttcgtg agttgcaaac tgcggggcag
    25381 tgggctgttg ttcgtgtttt acggaccatt ttggatataa tgaaagatct tgataaagtg
    25441 ttccctccaa cacgacattc aatagttgaa gtcctcggca gactgcaaaa atcggttttc
    25501 tttgtttcaa tgcttccaag atcaatgcct gttcgaattg gtctcgttga atatttgttt
    25561 ccgtcagttt tggatgaggg tcttccatgt aaagttgcgg actaacatcc tgaccgcctg
    25621 caagaatgag tttgtcgatt ttctcaatta gttgaggcgc tgaatctgga gacatgactg
    25681 gcagaataag aggtaatcct tgagcatcta aaactgcatc cacaaatccc tgcggtgtat
    25741 agcttacttg atttccttgg aaagtatctg tcgctcgaat cagttgattc ccggcaatgc
    25801 cgatgattgg tttcattttt attcccccta aagtagacta attgtaacaa ggatttaaaa
    25861 aaatttaaac tatgtaagac ttgcccctat acttatctgt tcttgctgtg ttactatctg
    25921 taaagagaat tttcgtgtga aattcatgac gatagttgaa aatattgctt aatttgttat
    25981 aataaaaagt aagcagaaat aaaaaggttg ggcgtaagct tcaaggatct agttcttcaa
    26041 ggggtgagaa ggacatttta ttgaaggggc ctgcctatac taagttatct ttagaggtac
    26101 atactttcaa tgaaaaaaga aagcatgtac ctctttttta aatcgaaagg aagtgaagca
    26161 agtgttagaa gctttggaac aaatccgaaa agcagaagaa gaaaatgaga agcgtgctcg
    26221 aaccctacgg cagcagttga agacctatgc agaagaaaaa gagcaagaat tggagataat
    26281 ccaaacgaac agtcggcaac agctgaaaca gttggtagaa gaaaaagaac aattcgaaaa
    26341 gcaagaatta gaaaaagaaa aaatgaaatt gaaagcagaa gcagacaagg tgcaagcaac
    26401 tttgaaagac caatatcaaa agcatcagag tcaagcaatc ggtgcaatca ttgaaagggt
    26461 gaaagaaact tatggccgtc actaagatgg aaaaagtgac cctcatttca gataaaagaa
    26521 atcaggagag gattttacaa gcagtacaag gaatccaaaa tgttgaaatc cgggatctgt
    26581 atcaaaatag aacaaacaac cagtgggtag aaaaatattt tccagatacc acgattattg
    26641 ataaagaagc aaaattaagc gctttaggca atcggctgaa agacatccaa gaagctatcc
    26701 aattcataca acaccacggc gatagccgtc aaaagaaact ccatttgaaa cgtcaagaac
    26761 tttccttaca agacttggaa gcaaattatt ccgaagaaaa tttcatgaat aaattagaag
    26821 aagtccttga tttaaaagaa aagtgggaac agctaactga aaaacgtgat cgtttagaag
    26881 aagaggaaga atggcttctt cattggcaac agctggatat tgctccaagt atgtatgcaa
    26941 gtaagacgac catttttgag atggggactg tgagtgcagc aaattttgaa agtttcaagg
    27001 aagaactaag taagcttgat gacgtttata tggaagaaat agattatacg ccaaaacaag
    27061 tttatctttc gtatgttgct ttaaaaaaat cagttgctgc tatagaagaa attgctggga
    27121 aatacgggtt caataaagaa acgtatcctt atgaacaaaa tcctaaagaa aaattgcaag
    27181 aaaccaaaca gcaattatcc attgttcacg agcagcaaaa aaagataacg acagcgttag
    27241 gtcagtgcag cggctatatc caagaatttg aatgggtaga agaagtcaca cttgccgttg
    27301 cagaacggga aaaagtaaaa gaacggttta tccatgccac ttatctgatc gttttgcaag
    27361 gttgggtaga tgcagaagaa aaacagaatt tgatgcatgt gttaaacgaa actgtatcag
    27421 aagaagatat atacgttagt ttcgaaacac caaactcaga agagattcag caggaagtcc
    27481 ctactaaatt gaaaaaccat ccgcttatcg aaccttttga attgctgact gaaatgtaca
    27541 gtctgccaaa atatgaagaa gtagatccaa cgccttggat gacaccattt tatcttgtct
    27601 tcttcgggat gatggtcgca gatgttggtt acggattgct gatgctcatt gggacaatac
    27661 tagctcaaaa actatttgtt ttaccccgcg ggatgaaacg tttcgtaaaa ttctttgaga
    27721 ttctctcggt accatcgatc atctggggat tgatctacag ttcatttttc ggacaggcat
    27781 taccaaaaga actatttggt atccgcttgc ctttcccaat cctatctacg acggatgacg
    27841 tcaatacgat tttgatttta tccgtgattt tcggtctgat acagatcttg gttggattat
    27901 tcgtggcagc aaaggaaaat atcaggagga aagattactt gagtgctgtc agtgatggtt
    27961 ttgcctggca agggatcctg attgggatcg ttattgcatt gattggtgtc atgttgataa
    28021 aaaatacagc atttgtttat cttggcgcgg ggctatcgat cattgctgct ttatgtatct
    28081 taatcgtgcc gattatccaa tcgccgtcta aagtcaaggg tgctgccaaa ggagcgtata
    28141 atctttacgg attgactggt tatatcggtg atttagtcag ttatacacgt ttgatggcac
    28201 taggtatttc aggcggaagt attggcgcgg cattcaatat gctagttgct ttcatgccgc
    28261 cagccgctcg attcagtgta gggatccttt tgatcatcgc tttacacgca ctgaatatgt
    28321 ttttgacact gttaagtgcc tatgtccatg gtgcacgatt gcagtatgtc gaattttttg
    28381 gaaaatttta tacaggaggc ggacgtgcct ttgacccgct gaaaacggcg gaaaaatacg
    28441 tcaacatcaa tcataagaaa aaaaacaata aataattgga ggatttttat acaatgatgg
    28501 attacttaat tagtcaaaat ggtggaatgg tatttgcagt attagcgatg gcaacagcga
    28561 cgattttttc agggattggt tcagctaaag gtgttggaat gacaggtgag gcagcagcag
    28621 cgttaacaac aagtcaaccc gaaaaattcg gacaggcttt gattctgcaa ttgcttccag
    28681 gtacgcaagg gttgtatgga ttcgttatcg cctttttgat ttttatcaac ttaggaaatg
    28741 atatgtcagt tgtacaagga ttgaactttc taggcgcttc tctgccgatt gcttttacag
    28801 gtttgttttc aggtatcgcc caagggaaag ttgcagcagc aggtatccaa attttagcga
    28861 aaaaacctga acatgctaca aaaggaatca tttttgctgc gatggttgaa acatatgcga
    28921 ttttaggttt cgttatttcc ttcctattag tattgaatgc ctaagcataa aggaggaaaa
    28981 gcagatgaac gccattgaaa aaatcatctc tcagatgaat gaagcagcag agcaagaaag
    29041 agcggcgtta gagcaagaag agcgaatgaa gatcgatcaa aactttgaac aaaaacgtac
    29101 gcaaatcgaa acagaacatc aaaaacaaaa agaaaaacaa atcgaattac ttgaaaaaaa
    29161 ataccgtcag cttaggaatc gccaacaagt agaagtacga caagaaaatt tgaatgcgaa
    29221 gcaggaattt ttacgacgat tgtttgcaga tgcaatagct gaaatggaga attgggatga
    29281 atctgaacaa atccagttta tcaaaaattc attgtattca ttacctttga caggcaaagt
    29341 aacattcatt gctggagaaa aatcagcagc ttatctttct cagacattgc tggatgaatg
    29401 gaacaatgaa cttcccttta tgatggtttt aagtgatgaa actgttgctg atcaagcggg
    29461 ttttctgata aacgatcaag gagttcagta taattttctt ttcagcagcc ttgtacaaga
    29521 tatccaagga acgatgagtt ttgagattgc caatcaatta ttcgaataag gagggatcag
    29581 tgtatggaat accacgaact aaatcccttg attcgcggaa gagagcttga acttttgtcc
    29641 aatgagacat ttgaacggat gattcaaaca aattctgtcg aagcacttgg tgaaatattg
    29701 aaatccacga tttacagtcc atatatttat gacggatatg aatatgactt cgaacagaat
    29761 cttttaaagg agcagagccg tctatttcgc tggttaaagg aatcagcacc ggagcctgaa
    29821 atcgtttgga tctatacgat gcgctatact ttccataatc tgaaggtttt gacaaaagcc
    29881 gagatgacaa atcaaaatct ggaccatttg tatatcgacg atggatttta ttcattagaa
    29941 accttgaagg atgccattca tacgcaagtt tcaaatgaac tccctgaaag cattatggac
    30001 agtatacgag aagtacgtga ttattttgaa gagtctacca ttcttcaggg aattgacgtg
    30061 atttatgatc gacagttttt gacagagcag cgacggcttg ccgataagct aggatatcaa
    30121 gaattgctga cagaagtcat tgcttttatt gacttgacca atatcacaac gatggctcga
    30181 ggaatattgc agaaaagaac atatgggttc atgacgacgg tactttccag ctcgggaagt
    30241 atcgaaaaag aagtattttt gaactttgta gataaagata tggaagatta cacgaatttt
    30301 ctattagaga cagattatgc tgattttctg cgccctgtca tccgtgaggg aaatcttgat
    30361 ctcgtaaagc ttgaacagtt gaaagatgat tatctaagtt cattgtatca agaagcacaa
    30421 acccaggctt tcggaccact gccactacta gcctttttga acgcaaaaga ggtagaaagc
    30481 aaaaaccttc gtttactggt tatcggcaaa agaagccatt tcgaaccaga aacaatcaga
    30541 aagcgggtga gacaagtcta tgacgcataa gatcggtgta gttggcgaca aagattctgt
    30601 tttgccattc aaattgtttg gctttgatgt tcgttatggt acaaccaagc aaaccgttcg
    30661 tcaggcaatt gaagaaatgg caaagaatga gtatggcgtg atttatgtca cagagcaatg
    30721 tgcagcattg agcccagaaa cgatcgaacg ttacaaggaa caaatgatac ctgctatcgt
    30781 attgattccc aatcatcaag gatcattagg gatagggctg gaagaaattc aaaaaaacgt
    30841 agaaaaagca gtaggtcaaa atatcttata gtatgaaaag gagatagaaa ttttgcaaat
    30901 tggaaaaatc ataaaagtct ccggacctct tgtaatggct gagaacatgt ctgatgccag
    30961 tatccaagac atgtgtctag tgggagatct aggagttatc ggagaaatta tcgagatgtg
    31021 tggcgatgtg gcgtctattc aagtatatga agagacttct ggaattggtc caggcgaacc
    31081 ggttcgctct actggtgaag ctttatctgt tgaattagga ccagggatca tttcacaaat
    31141 gtttgacgga atccaacggc cattagatac ctttatggaa atcacacaaa gtaatttctt
    31201 agggcgcgga gttcaattgc ccgcattgga ccatgagaaa aaatggtggt tcgaaccaac
    31261 agtagaagcc ggagaaacgg tgagtgctgg agatgttatc gggatcgtag aagaaacaaa
    31321 agttataaaa cataaaatca tggtgccaaa tgggataaaa ggaacgatca aaacaatcga
    31381 aaaaggttca ttcactattg atgaaacagt atgtgtcatt gaaaccgaaa atggtgacaa
    31441 aaatttgacg atgcttcaaa aatggccagt aagacgtagt cggccaatca aagaaaaatt
    31501 aaacccggat gcacccatga tcactggaca gcgagtgatt gatacattct tcccagtgac
    31561 aaaaggagga gcagcagctg tacctggtcc ttttggtgca gggaaaacag tcgttcagca
    31621 tcaaattgca aaatgggccg atgtggacat ggttgtctat gtgggatgtg gcgagcgtgg
    31681 aaatgagatg acggatgttt taaatgaatt ccctgaattg attgacccta atacaggaga
    31741 atcgttgatg gaacgtacgg tattgattgc taatacatca aacatgccag tagcagctcg
    31801 agaagcttct atctatacgg gaatcacaat tgcggaatat ttccgtgaca tgggttatga
    31861 cgttgctatc atggcagact ccacttcacg atgggcagaa gcacttcgtg agatgagcgg
    31921 acgtttggaa gaaatgcctg gtgatgaagg ttatccagct tatcttggtt cacggcttgc
    31981 ggaatactat gaacgatctg gaagagtcat tgcattagga tcagaaggtc gcgaaggaag
    32041 tataaccgca atcagtgctg tatccccgtc tggaggggat atttcggaac cagtcacaca
    32101 aaatacattg cgggtcgtaa aagtattctg gggtcttgat tccagtttag cccaaaaaag
    32161 acattttcct tcgatcgatt ggatacaaag ctattctctt tattcaacag aagtagggaa
    32221 gtatatggat catatccttc aagctgactg ggcatccatg gtcaccgagg gcatgcgtat
    32281 tttgcaggaa gaacagcagc tgaatgaaat cgtgcgtttg gtagggattg attccctttc
    32341 agataatgac cgtctgacat tagaagtggc aaaatccatt cgtgaagatt atttgcagca
    32401 aaatgctttt gatgatgtcg atacattcac ttcaagagag aaacaattca aaatgttgaa
    32461 gatgatcttg acctttggtg aagaaggacg ccgtgcgttg tcgttaggtg cttatttaag
    32521 tgagatcatg gacggtaccg tatcgattcg tgaaaggatc ggacgaagca aatatatccc
    32581 ggaaacagaa ttagaaaaac tagatcaaat tattggtgaa atcaagcaaa cgatgcaaac
    32641 gatcgtttca gaaggaggca tgagcaatga ttaaagaata tcgtacgatc ggtgaagtcg
    32701 tcggtccatt gatggcggtt gaaaaagttg ctggtgtcaa atatgaagaa ttaatcgaag
    32761 tccgtatgca aaatggcgag attcgtcgtg gacaagtatt ggaagtccaa gaagataaag
    32821 caatggtcca aatattcgaa ggaacaagtg gtatcaattt acgtgactct tctgtacgat
    32881 ttttaggcca tcctttagaa ctaggtgtat cggaagacat gatcggtcga gtattcgatg
    32941 gtttgggacg accgaaagat aacggaccag agatcctgcc tgaaaagcat ttggatatta
    33001 acggagaagt aatcaatcca gtagctcggg attatccaga tgagtttatc caaacaggta
    33061 tctctgcaat cgatcatttg aatacattag ttcgtgggca aaaattacca gtattttctg
    33121 gctctggtct tcctcataaa gaattagctg ctcagatcgc gcgacaagca acggtactcg
    33181 attcatcaga tgatttcgcc gtagtctttg ctgctattgg aatcactttt gaagaagctg
    33241 aatttttcat ggaagatttt cgtcaaacgg gcgcaatcga ccgttctgtc atgtttatga
    33301 atttagcaaa cgaccctgca atcgaacgta tcgctactcc tcgtatggct ttgactgctg
    33361 cagaatatct tgcttatgaa aagggaatgc atgttttggt tatcatgaca gacatgacca
    33421 actatgcaga ggcattgcga gagatttctg cagcacggcg agaagttcca ggaagaagag
    33481 gatatcctgg gtatctttac acgaacttag ctactttatt cgaacgagca ggaagaatcc
    33541 gcggactaaa aggatcggtt actcaaattc cgattctaac aatgccagaa gacgataaaa
    33601 ctcatccaat ccctgacttg actggttata ttacagaagg acagatcatc ttgactagag
    33661 agctttacaa gagtgggatt cagccaccaa ttgatgtact cccgtctctt tcgcggttaa
    33721 aagataaggg aactggaccc ggaaagacaa gagaagacca tgcagctacg atgaatcagc
    33781 tttttgcagc ctatgcacaa ggaaaacagg caaaagaatt agccgtagtt ttaggtgaat
    33841 ctgctttatc tgatgtagac aagatctatg cgaagtttgc tgagcggttt gaaaaagaat
    33901 atgtcaatca aggattctac acgaaccgtt cgattactga aacacttgat ctagggtggg
    33961 aactgctatc gatgttgcca agaaccgaat taaaacgaat caaagacgac atgctggaca
    34021 aatatctgcc agaagggaag tgagttctga tggcacgatt gaatgtgaat ccgacccgca
    34081 tggaattgac tcgattgaaa aaacagttga caactgccac aagagggcat aaattattaa
    34141 aagataagca agatgaactg atgcgtcaat tcatcctgtt gattcgaaag aacaaccagc
    34201 tgcgtcaaga aatggaagag tctatgacag aagcaatgtc tgattttgta ttggcaaatg
    34261 cttcgatcac ggaacctttc atcgaagaat tatttgtttt gccggcggaa aacgttgatt
    34321 tgtctatcgt agacaaaaat atcatgagtg taaaagtacc tgtgatgaat tttgaatatg
    34381 atgaacagct gacagacaca cctttggaat acgggtattt gaattccagt gccgaactgg
    34441 atcggtcaat cgatcggttt actaccctgc ttccaaaact tttggaactg acagaaatcg
    34501 aaaaaacttg tcaactgatg gcgagtgaaa tcgaaaagac acgtcggcga gtcaatgcat
    34561 tagaatatat gacgatccct caattagaag aaacgatcta ttatattcgt atgaagctgg
    34621 aagaaaacga gcgcgcagaa gtaacaaggt tgatcaaagt aaaaaatatg ggtaccactg
    34681 actaagtggt atcttttttt aaaagaggaa aacgatgatt aaacaaagca aacaaataaa
    34741 gaaacgtttg ccggctgttc agcttctcgc attaggattt tttctcctga ttttagttgg
    34801 cggcggccta cttaccctac cattttttag taatagtggg catgggacaa attttatcga
    34861 tgcgcttttc actgcaactt ctgctgtctg tgtaacggga ttgacaacat tgaatacagc
    34921 agagcattgg aacagtgctg gtcaattttt gatcatgctt ttgattgaga tcggcggtct
    34981 tggttttatg atggttccga ttctatgctt tgcattgata aagaagaaag tcagtctcag
    35041 cacacgtatt atattaaaag aagcgctgaa tctagaagaa gtatcaggtg tgatgaagct
    35101 catgctttac atcctaaaat tggcctttgt tatccaattg attggtacgg ttgctttatc
    35161 ttttgtattt gtgcctgaat ttggctggtt gaaaggtatc tggtacagtt tgttccatgc
    35221 aatctctagt ttttgtaatg cagggtttga tttgttagga gacagtttag ccaatcacca
    35281 gcaaaatgtt tatttgatca tggtggtatc tgctttgatc atttctggtg ggttaggctt
    35341 catcgtatgg cgtgatttac tggaatatca tcagaaaaag aagatgacga ttcattcaaa
    35401 aatcgcatta accgttacag gtaccctttt attaggcgga ttcgttgtgt tctttttcac
    35461 agagcgcaat ggggcaacgc tagtggaagg gaatatgttt caacgattgg caaacacctt
    35521 ttttatgagt gtgacaccta gaacggctgg atattattca gttgattacc tccatatgag
    35581 ccatgcaggt ctgattttaa cgatgttttt gatgtacatc ggcggaacat ctgggtcgac
    35641 ggccggcgga ttgaaaacaa ctacgttagg tgtgttgctg atccagatgc gttcgatgtt
    35701 gaaaggacgt acgagagcgg aagcatttgg ccgtaccatc cgacaaggcg cagtgttgcg
    35761 ggcacttact ttattttttg ttacgttgac gttgtgtgta gtcgccatca tgattttatc
    35821 ggtgactgaa acgataccta aaacttctgg catcgaatat attgcttttg aggtcttctc
    35881 tgcgtttggt acagtaggtc ttacgatggg attgacgcca gacttgactg caatagggaa
    35941 attgatcatt atagcgctta tgtacattgg acgagttggt gtattgactg tggtcttctc
    36001 tctgatgaca aaagcacaaa gaacacaatc aaaatacaaa tatccagaag aaagtgtcat
    36061 gattggataa tttcatcttc tgacagaaac ctagtgattt agtaaaataa gaaaataaaa
    36121 taatttttct tgcttcttgg atactttaag tgcaaaatgt tcgtttattt tttgaggcac
    36181 tacccgttgt tgaacctcgg gtagtgcctc ttttttattg aaaggaatca ataagatttg
    36241 attcctttat ttatcaatag gttataattc atattttttt attttttctt ttacgatact
    36301 tagtccagaa gctaaaattt caaggttatt agaggatagg gaaattcgaa cgaatgcatc
    36361 tggttgcgca cgtgtagtaa agcgtctgga atgataaagt cggataccgt tagcaagaaa
    36421 gtcattctca attatcttag ggtcaatctc aggatcaact ggaagaattc gatagtaagg
    36481 gacacgattc gttggttttt ctactttgaa aagagaatca aaaagctgat tggctctttt
    36541 tgtaagactt aatttagttt ctaagatcct atttgcttca tttgaatgga ggatttgagt
    36601 gatgacttcc acatctaatc cagaagtttt cacatttata ttaaaaattg cttgttctat
    36661 cttgctttgg acatgtactg gaactacaag ataagcaact cgcaatccag aacaaataaa
    36721 ttttgtcatt ccagctaagt agattgtttg gttaggtaat aaattttgga aaggaggaat
    36781 gatcgtatgt tgatagtaag ttgttaaaaa tgaatggata tcatcttcaa taacccatag
    36841 accttctttt tcaatcactt cggctaattg ctctcgtctt ttgtgagaga tttgaaaccc
    36901 tataggatta ttacaagaag gcataagaaa gacaccatga atcttctttt ttctacattc
    36961 ctgaatcaat atatcaggtc gcattccttg ctcgtcaaaa tcaattggaa cgatctctaa
    37021 atgatataac tgagccaatt caatgaaatt agcgtatgta tatcggtctg ttgctattct
    37081 atcacctgga gagaaaagtg cagaaagtgt gatagccaat ccattttgaa caccggaaac
    37141 aatagataga gattctaagg acggaatgac tccttgagtt tttaaccaat ttgctgcagt
    37201 agtcaattga aaatttgtgc ctttgggatc ttggtaatta agcaaaccaa caagatttgg
    37261 gttattacta gttgattgaa taaacgggac aacgaattta ttacattctt caaaagaact
    37321 aaccagacca aaatcaatga tatgttcggt tacttcattg gtagagatgg tgatggactc
    37381 aaagacattg ggagaaataa atgtgccact tccaatattc gtatacagca aacctttctc
    37441 aattccatat ttataagcct tgccaacggt agtaaaattt aaatctaaat aatcagctag
    37501 ctctctttgg gagggtaact gagtgttttt ctgtaattta ttctttaaaa tatcttgttc
    37561 taattgttga atcaacgatc gataataagg acgcttcaat ttttgtttgt ctggtcgcca
    37621 agttaacggg taattgtcat aagaattaat aggcattttc tccactcctt aaaattgtat
    37681 accatacaat tttaccattg attgtattga ttttagaagt taatcttttg tgaggaggga
    37741 attgtctatg aaaattatta attttgagga agtagtagct tcttttagtt ttgaagaagc
    37801 gattcaagta atgaaaaaat gtttttttga ttatgaaagt ggtaaaatca gccaaaatcc
    37861 tcgattggtg gaaattttac ctgacggaaa aggcaaaaat atgtttgcga tgatgcctgc
    37921 ttatttgggg gagaacagat attttggcac aaaagtcatt accgcttttc cggataatca
    37981 tcagtatcat ttaccttctc atttaggaga gattttcttg tttgatgctc aaaacggact
    38041 acccaaagca ttgataaacg caaatgcagt cacctggatt cgaacagctg ctgtatctgc
    38101 gctggcaaca gattacttag caaatccgca tgcagaaaca cttgctttaa ttggagctgg
    38161 tcaacaagca ttgtcgcatt tgactgcgat ttctaccatt cgtcccatca ctacagtgtt
    38221 tgtttacgat attttagaag aaagacgaaa tacttttatc gctaaagcta aaaaacagta
    38281 tcctaaaata acgtttataa atgcaatatc agtagaagat gcagtacgtc cagcggaaat
    38341 catttgtacg ttgacctcta gtaaagaggc atttcttcaa aaagagtggg taagggaaga
    38401 cgcacatatc aatgctgtgg gcacatttac tcctgataca agagagataa gtacatcgtt
    38461 gatggaaact tctcaaatct atgtagatga ttactcagct gccttaacag aaagcgggga
    38521 cctgcttata gccatggcag aaggagattt agaggaatct tgtattgttg gtacattagg
    38581 cgaattagtt tctgagaaaa aaacatttta taaaggagaa tcgaggccga cgattttcga
    38641 cgcagttggt ctagctattg aagatctttg ttgtgcagaa tatatttata acaaattaga
    38701 gaaaggggct ttaaaatgaa cttagattat tacgtagttg atgcatttgc agatgaggtg
    38761 ttcaaaggaa atccagcagc ggtttatgtg ctagaagaat ggctgccaga aggtacgatg
    38821 caaaaaattg ccattgaaaa caatttatct gaaacagcat ttacagtgaa gaaaaaccaa
    38881 gaatttgagc ttagatggtt tacgccagat cgagaaatcg atctttgtgg tcacgcgaca
    38941 ttagcaacag catttgtttt atttaactat tacaaaatac ctgatgaaac gattaaattt
    39001 tctactcaaa gcggtaatct atttgtgaca agaattaaag attattatta catggatttt
    39061 cctagtatta tgccgaaaaa agtgccgata ttgtctgaat atgaagaagc gattggggct
    39121 aagattaaag aagcctactt agcacgtgat ttatttttcg tattagaaga tgaaaaaacg
    39181 gtggctaaat tgcagccaga ttttacagct atcaaaaatt ttgaattagg aataggagtc
    39241 atcgtgacag cagaaagtgt gcaaaaagac tttgtttcta gaaccttctt tccaaaatta
    39301 acaatcaatg aagatccagt atgtggatca gcacattcta atcttattcc ttattgggca
    39361 gaaagaatga ataaaacaaa attgtcagct tatcaaatgt catcaagggg cggggatcta
    39421 gaatgtgaat taaaagaaga tcgtgtgata ataggaggaa aagcagtttt gttttctaaa
    39481 ggtacctcgt ttatttgatt tctttcaaat gaattaaaaa taaattggtg gagagtggca
    39541 accttatagc tacaatggtt gttaaaaaaa gacgcaaact ttttcaattt aatgaaaagt
    39601 ttgcgtctca ttttaattat tggtgtttgt tttttattca atcaagagta aaatgcccca
    39661 tactaactat cctcggatga cttcgatttt ataaccatca gggtcaatga caaagtagta
    39721 agaaggcgca gtgccaggta atccttttaa gtcagtaatc tcaagaccgg cagctttatg
    39781 ttgctcgtgt aatttttcta gatcatcagc tgctatagcg atatgaccat agccgtctcc
    39841 tagatcatac gcaccatgat catagttgta agtcaactct aattcatagt catccccagg
    39901 aagtgtcaaa taaacaagtg taaatttgtt ttctggaaaa tcacggcggc ggctttcttc
    39961 aaaaccaaat gccttttgat aaaattcgat tgatgcttca agatctttca ctcgaacaca
    40021 tgtgtgagcc attttcatag attcatctct ccttttcctt ttactcaatc ataacaaaaa
    40081 gaagtaagga aatagttgat ttgtgcttgt tcatgagaaa tttctcatgt aaaatggata
    40141 gaaaataaaa ctgttaaggt ggaaactatt catggataaa ccaatttttg gtgaaaaaaa
    40201 gcaatttgct gattatcaaa cccgttatgc agcatatatt gtcatagaaa gagatcagca
    40261 gattgcagta atcgaggctc caaatggtgc tttttttctt cctggcgggg aaattgaagg
    40321 agaagagacg aaagaagaag cgattgtccg tgagctgata gaagaaatgg gaattgtggc
    40381 agaaatttct tcttatctgg gagaagctga tgagtatttt tactcgaatt atcgtgcaac
    40441 ttattattat aatccaggat atttctttgt tgctgattct tggaagcgta taggagaacc
    40501 aactgaaaag accaataaaa tttggtgggt gagccctcaa gaagcgcttg tgaaattgaa
    40561 acgtggtagc caccgatggg cagtcgagag atggatcgaa aaaaataaaa actgaaagaa
    40621 agcgagtaga tcagctttct ctcagttttt ttatttatta cagtacatat tttttgattg
    40681 cttcagctac accgtgctcg tcgtttgatg aagtgatgac atttgctgct tctttgacaa
    40741 gagaaacggc atttcccatt gctactccta gaccagcata ttcaatcatg gataagtcgt
    40801 tctcgttatc tccgatagcc atgatttcat cttgatcaat accaaggtgc tgtgcgagat
    40861 tcgcaactgc cgcaccttta cttgcttctt tatttagtac ttcgaagtaa tagggcgcac
    40921 ttttgaccgt tgtgtattta tcacggaaag tttgcggtaa acgcgcaatt gctgcatcta
    40981 aaatttctgg ttcgtcgatc atcatcattt tgacgatgtt catgtctggt gtcatttctt
    41041 caggtgttcg atattttagc ggcatcttga ctaaacttgc ttcgtggatc gtataagcgc
    41101 tgatatctcg attaggcgtg tagatcgctt tgtcatcgat cgaatggaga tgactgccga
    41161 cacggcgtgc catcacttcg atctctagga aatcttcatg tgtcagtccg tgacgggcga
    41221 tgattttacc tgatttcgtt tgttgtacga gtgccccgtt ataagtaata acgtaatcat
    41281 tatcttgaaa aaggttcaac tcgtttaact gttcctggac acctggtaag ggacggccag
    41341 tgcataaaac gatcgaaaca ccttttgcaa cagcagcggc aatcgcttct tttacttctt
    41401 ttgttacttc tcttttctca tttaataaag taccatcgat gtcgatagcg actagtttga
    41461 tagacataat ttcctccaat atattttaat ttatttcaat caatgcgcca ttacggatat
    41521 ggctggcaaa ttcttgataa gtttcgtcaa ataaatcata atgatcacgc aaggacggat
    41581 caaccatttc ttttggaaag aaaaatcgct catctccttg ttcttgtccc gctaatgcag
    41641 caacaagctg actaacctgt gataattcta tcaaagttcc gtcatttcgc aaaatctcga
    41701 tttgtgtgcg atgtctgcct tgttctgggc gataaaaatc ataaggtaga tcgtagctag
    41761 aattcacagc agtgtaataa acaggattat atccgacctt ttctactaac aaagtgagtt
    41821 cttggactaa ttttgaatcc cggttgccag aaaaagtagc agatttcagt ggtttacgat
    41881 tcaaaaaacg tttagctaaa tcatttaaaa taggatcagc agattcagac cattgagtaa
    41941 agtaagtgcc caagacccca tcatcaagtt tgaggtattc ttctaaagta aagcttccgt
    42001 caagaaatgg cagaagtaat tgagaatgga gttcaaaact gctggcatct tcttgataca
    42061 actcgtgtgc gcgatgaagc agatgctcca aaattacttc cataccacgg gaaacaggat
    42121 ggaagtacac ttgcacatac atttgatatc ggctaacgat ataatcttcc actgcatgca
    42181 tgccactcat ggaaaaagcg atcccgcctt cataaggacg aatcacacgt aatattcggg
    42241 taagatcaaa tgttccatat tctgttccag tgaaataagc atcccgaagc aaatagtcca
    42301 ttcgatctgc atcgatctga ctagaaatca tttggacaac ttgtgggttg gggtaagttt
    42361 tttggatcac actagctacc ttttcaggaa aaccttcttc tactcggtta agaatctgat
    42421 acacttctgt ttctggagaa gtgatgatct ctacagtgat ggcttcatga ttcgtatgga
    42481 agatatgttc aaatgtatga gagtaaggac catgaccgac atcatgcaac agtgccgcac
    42541 ataaagtcac cagccgttcc tgatcatccc agcctccgtt gcctattttt tcttttgaaa
    42601 aatttcgaga aaagatatcg cagattcgtc ttgaaatctc ataaacgcct aatgaatgag
    42661 taaaacggct atgttctgct ccgtgaaaag tgaaagaaga agtgcctaat tgtttaatgc
    42721 gtcgtagacg ttggacttct ttcgaattga tcaaatctaa gattacttga tgctggacat
    42781 ggatatagtt atggactgga tcacgaaaaa ctttttccat aggcagcatt tgatatttat
    42841 aaggggttgt cataatgtag ctcctttatg ttattacgtt gttccattct ctggatttgg
    42901 ttgttccatt gctccagctg gatttctttt tttagccagt cggtagaatc ctgtaaatca
    42961 cttgcagaat acagcttttc aaaagctttt gcaaatgctt ctttgacttc ttttacaaaa
    43021 aggggttggt caagcagttc ttcaagtgtt gccattgtag caggatccac tgcaggatag
    43081 ccatttgtac caaagtcttc ttttaaagca gattgataaa atcgcttcat gacttgcccg
    43141 cgtttttcct gattaccgtt gacacttaag tacatcataa cagaaatccc atttttgatc
    43201 cgacgctgag cgataccggc aaattttttg ccatggatgc ttaaatcata agttccagga
    43261 caataagaat gggtgatttc gaatgcttgt atcggtgcct ttggaaaagc gtatttagtc
    43321 aataggagca tttgctcgta agcgtcatct atggttattt tttttgtgtc actttggggg
    43381 aaaatcaaag aaatattcaa aattccttca tctgatacga tccctaatcc acctgaattt
    43441 ctgatcactg gagcgtaacc tgcatctttc agtgtttgga tcccgtcact tagaaaagga
    43501 gttcgaacat ccttcatacc taagatgact gtgcagtcat attgccagaa atgtaaaaag
    43561 atttgctggt gttctttaga atattccgtt aatatatctg ttaatgcaaa aggggaaaag
    43621 tcgttttttt gataaatgtg ctgatctagt cgaatcgcag ggttcattca accggctcct
    43681 ttgtataaat tcatattttc tacaatatta tactctaaaa tcaaagagtt gttttggaaa
    43741 aaaggttttc tgtaaaaatg gacaagttgg ttgacaaaac aaaagaaact aggaacaatg
    43801 tagctatgag aagtaaagga gaatgaataa tggaattatc acaaggaaca ccgatttcaa
    43861 tcaaattgcg tacaaaagta aaacagcaag gggaagtgca agatttttat tttgatttga
    43921 aagggcaaat ggtgacaatt ggcgatacgc tgtacatacg ttataaagag attcaggagg
    43981 agacgggcga tgagattcct gtaacgatca aattagttcc agatggtcat gtacagctga
    44041 tccgtgcagg agaaatgcgg atgcgtttga aatttggcta taaagaacgg ttagaaacat
    44101 cctatcgaac accatacggt atgatccaga ttgctacttt tacgaaagaa ctgcatgtta
    44161 gtttgaaaga ccgtcccaca ggagggaagg ttcgaatcga ttatgatctg ttcatgggac
    44221 cggaaaaaat cggcgaatat tatttgacct tggattttac agcgtaaata taaaagaaaa
    44281 gtttgatttt ttgtgtctga ttttgtatga taaggagtag actgtgaaag gacgtgtcct
    44341 gattggaaat tagtgtattt gaaggtgcaa acaaaagcga attatcaatg atcgaagtag
    44401 cacacgcgat cttagaacaa cgtggcgatg tcatggattt ttctgattta gctaaccaga
    44461 tccaaaacta tcttgggaaa tcagacagtg aaattcgtga ttcactcgca caattttata
    44521 ctgacttgaa tattgacggc agctttatct cattagggga taatcgttgg ggcttgcgtt
    44581 catggtatgc tatcgattcg atcgatgaag aagtaaacca tggaatggac gaagaggatg
    44641 aagatactcc acgtcgccgt aaacgcaaga aagtcaacgc ctttatcaat gatgatgaag
    44701 acgcgatcga ttacaatgac gatgacccag aagatacaga tctgacagaa gaagatgacg
    44761 atgatctgtt tgatgacgat gatgatgaag atgaagaaat cgctgcttat aattctgact
    44821 tgcaagaaat cggagcagat gacccgacag atgatgaaga agacttgcca ggaaatatcg
    44881 aagaagattt aagtatcata gacgaagacg atgatgatga agattatgaa gaggaagaat
    44941 tttctgactc tgaaaaagaa taaacattat tttcttacga gaggttgtga cagagacgat
    45001 cagcctatca gaataaggag gtgtgacacg atttttgtca caccttcttt tttgtatata
    45061 aaaatcccaa gtaaatacat aaaaaataaa aaaattgaaa cttttagcgc accttgtacg
    45121 tcatattaag tgaggcagaa aggagtggag aatgattttt actggatata agaaaaaacg
    45181 gcagatcgaa aaataccgtc acctgctgaa tggactcatc gaaactgatt atcaaaaaat
    45241 gttccgtatc acgatgaatt acgtacatga taaagaagag gccttagatg tgatgcaaga
    45301 tagttttcat aaagccctga actattttga aaaagaaaaa gagatcgagc attttagtgc
    45361 atggttttat cggatattga tccgcacggc attagatagt tggcgcagac aaaaaaggac
    45421 gcctgtggac ttatttgaaa ttcaagatat cccccaacag ttacctttag aaacttccgt
    45481 tgcagagctc catatgattt tagataaaat agacagtccg gaaaaagaga ttctgatcct
    45541 ctactttttt gaaggatttc gtttgaaaga aattgcgact atcttggata tgaatgaaaa
    45601 cacagttaaa acgaaaatgt accgctcatt gaatgcttta cgtcaaatcc tagaatgaag
    45661 gagagaagag tgccatgtat tcccaaaaag aaaatttaaa aaaactaaag aaaacttata
    45721 aagaacaagc aattcccaaa gggcttaaag aggagatccg ccagcgtttt attatcgaag
    45781 agcaatcatt tataaaagca aagcggagaa agagacgtct ccaagggttc ggagtatctt
    45841 tggctatcgt aatgattaca acaagtagcc ttctttttaa tagtcaagtt cgaagctttg
    45901 cagaagattt acccatctta ggatcagtca ttgaattgat cttaggcgaa cgctttactg
    45961 atcgatctga aaaaatcgat attcaggtac cgaagatcaa tacacaaaat gagaaagaaa
    46021 ataaaacaat tcatggatta aatcaaaaat actttcgcga aggacaagca gattttgaaa
    46081 aagctgaaaa agaatatgga aattttgaaa cggatcatta ccaagttttg ggagattatc
    46141 agaaaatcgt agacgataac cggtttctcg tgattgaaag gcagatcacc caaacagcag
    46201 cagatagcca tgttgaaaaa agatacgaca caatcgacaa gaaaaacagt gtccagctct
    46261 cacttccact tttattcaaa gatgacacct atctatctgt tttgacaaaa gaagtcaaac
    46321 ggcagatggc cgaacaagtc aaggaagatc catctaagta ctattggact gagcaagata
    46381 ttcaagaagg gacgatagaa aaaccaacac ttgttacgcc tacacgaagt ttttatttga
    46441 acaaagagca tcaattagtt ttgacttttt ctcaatacga aattgctcct ggttatatgg
    46501 gtacaccaga atttgtcatt cctaagtccg tgacaaaaac gattttggca tcggaagatt
    46561 atttggatca ttagacgaga agtagttgcg actagcagtt tcaattttca agtaagtaca
    46621 agtaaataat aagaagagaa aaagagaaag aagagatata gtgaaaagaa attatttagt
    46681 tatcagtatt attgctttat ccgtgctttt gtttttcgaa attacttcgg tggcctcctt
    46741 gatcaccgaa gtaaaaggac aaacacactc ttcggagcat tcgtcacaat ctttcaaaca
    46801 atcagaacaa tcaaccatta aaagccaatc aactgaaaca gctaacgtca aagaagccat
    46861 tcaagaatca gcggaaaagg tacaaagtca gtcatcacaa tcaacacaag acagtacaaa
    46921 aacgagccga gatccggctg tcaaaagcgt cgcaatcagc tttgatgatg gaccaggagc
    46981 gaccacaaca ccgcagcttc tgcgaatctt aaaagaaaaa aacgtgcatg ccactttttt
    47041 cgtcttagga gaaaatacgg cgcagcatcc tgaaatcgtg aagcagacag ctgaagcagg
    47101 gcacgagatt ggcaatcaca catacgatca tcagaatctg gccactcttt ctgcccagtc
    47161 gatgacggag gaagtgacga aagcagacac tgagatcaaa aaagtcactg gcaaaacccc
    47221 cacttttgtt cgtccgccct atggttctgt cacgaatgta ggagcaacga tcatccagcg
    47281 accgatcatc gaatggtctg ttgattcaga agattggaag acaagaaatc ctgatttgat
    47341 tttgcagaag atccaagcaa cagtatacga tggggcaatt attttattcc atgatatcta
    47401 tcctgaaacg attcgtgccg ttcctcaagt gatcgattat ctgaaagagc aagggtatcg
    47461 catcacgaca gttggggatt tattagggca tccaacggct gtcgagaact attatggcag
    47521 aaacgatcat cggccagttc agtaagtgag acaagtatct ttaataaata acacatttta
    47581 ataagtagtt gaacacataa ctaccttact tgcaaaggct taacaatatc tatacaggta
    47641 caacaaaaaa ctgtccacca attttctttg gcggacagtt ttcacttaaa aataaagaag
    47701 caactattcg taaattatgc taaaatagca gtagaacgcg tcctgaggga atcgaacccc
    47761 cgtctcaaga accggaatct tacgtgatat ccactacact aaggacgcaa gcactgggat
    47821 aattgtaact aaacagataa aaaattacaa ggggattgga caaaaaaatg aaatttgagc
    47881 aaaatttttc acaaaaacag cagcagacac agaaactagc catgacgcaa cagttgcaac
    47941 agtccatcca agttttacaa tataacagtg aggagctgtt ggcattcgtt gagaatcaag
    48001 caatggaaaa tccattggtg gaagttgttg agccggaatg gcagccagat tacataaaag
    48061 cttcttcatc ttcttatgaa ggagaagaga caaattacct aaatcagatt cctgatacaa
    48121 aagggtcttt atttgattca ttgatcgaac aagtccattt gaattaccga gatacttttt
    48181 tgaggaaaat cgttctttat cttgtagaat acatcgattt gaacggattt ttgacgatta
    48241 gtttagaaga agccggaaaa gagattggag ctacgcctat ccaaatgctc gatgcgttga
    48301 ctctgattca gcaattagaa ccagctggag taggtgcacg tagtttgcaa gaatgtctca
    48361 tgcttcaaac agaacgagat gattatgcgc cggaattagc ttatatcgtg ttggaagaat
    48421 gttttgagga actggtggag cgaaaatgga aagaaatcgc acaacgtttt tctgttgatc
    48481 tacatgctgt tcagcagata ttcgactatt tacaaacgtt gagtccaagc cctggccgga
    48541 ttttcgaccg tagcagcgaa ttgtacatta ttcctgatgt ccgggtatta gtggacgacg
    48601 ataaaaatgt acaagttatc tcaaaccgaa aaaatcagcc aaatatacgc tttcaagaga
    48661 gttacttcaa acaaatgtca caacaagcag ataaagaaac tgaaaattat ttaaaagaac
    48721 ggaaacagga attcgaatgg ttgaagaaaa cgatcctaca acgtggggat acaattttgc
    48781 gggttgctca agtcattgtt tcccggcaaa aagctttctt tatcgacaag gaacgtccaa
    48841 tcaagcctct tacgttaaag gaagttgcaa ctgagataga tgtgcatgaa tccacggtca
    48901 gtcgtgcagt caacgggaaa tatttggaaa cagacttcgg tgtatttgaa ttaaaaaaat
    48961 ttttcactac acgaattcct acgaatagta cagaacagac agaagacctt tcagcagata
    49021 cagcgaagaa aaagctgcag gaattagtcg atcaagaaga caaaaacaag ccgttgtctg
    49081 accagaaatt ggttgaattg ctgaaaaaag atgagatagc gatctcaaga cgaacagtag
    49141 caaaatatcg tgatttatta ggaatcccga gttcatcaaa aagaaaacgt tatgataact
    49201 aatcagtcaa aagactagaa aaagtatttc actttttcta gtctttttag ttgaaaaacg
    49261 agagcaaaac tgttagactt acagtcgtga ggttgagatt tccctttatt gatgtgaaat
    49321 tcgaatagtt aatttctttt tttatcgtat atgggtcgtt ttaagtctac attggacgta
    49381 aagtgtccaa ctaaggagat cgctatgctg gatgaaataa aaatgattga atctgttgca
    49441 ccagatatta tcgaagtgtt gcaagaacgc tataaaattt tacgaaatat ctattggatg
    49501 cagccgattg ggcgtcgaag tttatcggaa agtatgggga tcacagaacg agtcttacga
    49561 acagaaacag accttttgaa aaatctgaat ttgatcgaca cctcaaaaag cggtatgacg
    49621 ctgacaacta agggcgaaga agtttatcaa agccttgaaa acttcatgga tcagctttta
    49681 ggtacgcatc aaaccgaaca acagttggca gaatattttg gtaaccaacg ctgtatcgtt
    49741 gtttcaggaa acagcgaaga gcagaccaaa gtggctgatg cattcggcga agcgctgagc
    49801 gaagccttag accgactact tccagaaggc gagaatatca tcgctgtgat gggaggaact
    49861 actatggctg tggtagccga acaattgtct aatctggaaa ataagaaacg gcataacctg
    49921 tttgtccctg caagaggcgg gattggtgaa gcgataactg tacaggcaaa ttctgtcagt
    49981 gcaagaatgg ctgctaaagc aaacggtaac caccgcgcac tttatgttcc ggaacaatta
    50041 agtctggcaa cttacaattc tttactcaat gagccatcta tccaagaagt cttaaacttg
    50101 attagtgaag cgaattgtgt tattcatagt attgggcgtg cattacacat ggcagcacgt
    50161 cgtaagatga ctgaaaaaga attagtcatg ctgaaacaag caaatgctgt tgcggaatct
    50221 tttggctact ttttcaatga aaaaggtgaa gtcgtttata aggtccctag aatcggcata
    50281 gaattgcaag atttggaaaa agtcccgatc atcatggcaa tcgcgggcgg aaaatcaaaa
    50341 gctaaagcaa ttcgagctta tatgaaaaat gcaccaaaac aaacgtggct catcactgat
    50401 gaagctgctg caaatgagat tttaaaaggg gtaacccttt aaaataaata tttttttgat
    50461 tttcataagg aggaaatctt aaatgacagt taaagtaggt attaatggtt ttggacgtat
    50521 tggacgtcta gcattccgtc gtatccaaga tgtagatgga atcgaagtag tagcaatcaa
    50581 cgacttgaca gatgctaaaa tgttggcaca cttgttaaaa tacgacacaa ctcaaggacg
    50641 tttcaacgga acagttgaag ttcatgaagg ttcattcaac gtaaacggaa aagaagttaa
    50701 agtattagct aaccgcaacc cagaagaatt accatggggc gaactaggcg tagatatcgt
    50761 tctagaatgt actggtttct tcacttctaa atcagcagct gaaaaacatt taacagctgg
    50821 tgctaaacgc gttgttatct ctgctcctgg cggaaacgat gttccaacaa tcgtttataa
    50881 cacaaaccac gaaacattaa ctggtaaaga aacagttatc tcaggtgctt catgtactac
    50941 taactgttta gctcctatgg ctaaaacatt gaacgacaaa tttggtgttg ttgaaggatt
    51001 aatgacaact atccacgctt acacaggtga ccaaatgact ctagacggac ctcatcctaa
    51061 aggtgacttc cgccgtgcac gcgctgctgc tgcaaacatc gttcctaact caacaggtgc
    51121 tgctaaagct atcggtttag taattcccga attgaacggt aaattagacg gagctgctca
    51181 acgtgttcct gtaccaacag gttcattaac agaattagta acagttcttg aaaaagaagt
    51241 aactgttgac gaaatcaatg cagcaatgaa agaagcttca aacgaatctt acggatacaa
    51301 cacagacgaa atcgtttctt cagatatcgt tggtatgact tacggttcat tatttgatgc
    51361 tacacaaact aaagtaatga cagttggcga caaacaatta gttaaaactg ttgcttggta
    51421 cgacaacgaa atgtcataca ctgcacaatt agtacgtact ttagaatact tcgctaactt
    51481 ataagataga caaacgtaca agtgtaaatt atagacatgt acatttaaaa gcggggaagc
    51541 aatcgcgctt cttccgcttt ttttgataat aagtttattc aggaggaaat aaaatggcta
    51601 agaaaacagt gaaagatatc gatttaaaag acaaaaaagt tcttgtccgt gttgacttca
    51661 acgttccttt gaaagacggc gtgatcactg acgacactcg tatcaaagca gcattgccaa
    51721 caatcaacta cgttctagaa caaggcggaa aagcaatcct tttctctcac cttggacgtg
    51781 taaaaacaga agaagataaa gaaggaaaat ctttagctcc agttgcaaaa cgtctaggcg
    51841 aattattagg taaagaagta acattcgtac ctgaaactcg cggagaacaa ttagaagaag
    51901 caatccgcaa catgaatgac ggcgacgttg tcgtattcga aaatacacga tttgaagata
    51961 ttgacggtaa aaaagaaagc aaaaatgata cagaactagg taaatactgg gcttcattag
    52021 gcgatgtatt tgttaacgat gctttcggta cagctcaccg tgcacatgct tctaacgtag
    52081 gtatcgcttc aactggtatc ccaacagttg ctggattctt gatggaaaaa gaaatcaagt
    52141 tcatcggtga agcagtagaa gaaccaaaac gaccaatgat tgcaatcctt ggtggcgcaa
    52201 aagtttctga taaaatcggc gtaatcgaaa acttgattcc taaagcagat aaaatcttga
    52261 tcggtggcgg aatgacttac acattctacg aagcaaaagg aatcaagatc ggtaactctc
    52321 tagtagaagc tgataaagtg gaactagcaa aagaattaat cgaaaaagca ggcgacaaac
    52381 ttgtcttgcc aatcgacaat gtctgtgcac cagaattttc aaatgatgtt gaaacacaag
    52441 taatcgaagg agacattcct gatggtttga tggctttaga catcggccca gcatcagtaa
    52501 aattatttgc tgatacatta caaggtgcaa aaacagttgt ttggaacgga cctatgggtg
    52561 tatttgaaat gagtaacttt gctaaaggta caatcggtgt ttgtgaagca atcgctaact
    52621 tagaaggcgc aacaacaatc atcggtggcg gagactcagc cgcagcagca gaacaattag
    52681 gatttgctga caaattcaca cacatctcaa caggtggcgg cgcaagcttg gaattgcttg
    52741 aaggtaaaga attaccagga ctagcagcaa tcaacgataa ataaacgacc aagtttgctc
    52801 aattctgacg agtaatcgaa caaaaggtga agggagtttt catgactccc tagccatttt
    52861 tcaataaatt aaggagtgtg ttcctcaatg cgtaaaccta ttatcgcagg taactggaaa
    52921 atgaacaaaa ctgcatcaga agcaaaagaa tttgctgaag cagtaaaaaa caaaatccct
    52981 tcaaatgaca aagttgattc agtcatcgga tctcctgcat tattcttaca agaattaatg
    53041 acatcagctg aaggtacaga actaaaaatc tcagcacaaa actgctactg ggaaaactca
    53101 ggtgcgttca ctggtgaaac ttcaccagca gctcttgctg atctaggtgt tcattatgtg
    53161 atcatcggac attcagaacg tcgtgaatat ttccatgaaa cagacgaaga catcaataaa
    53221 aaagcgaaag ctatctttgc aaatggtatg acaccaatcc tatgctgcgg cgaatcttta
    53281 gaaacctatg aagcaggcaa aactgctgaa tggatcgaag gacaaattac agctggttta
    53341 gctgatcttt cagctgaaca ggtgtcaaac atggttattg cttatgaacc aatctgggca
    53401 atcggtactg gtaaatcagc tgacgcacaa atcgctgacg aaatttgtgg agttgtacgt
    53461 caaacagttg aaaaacttta tggaaaagaa gtatcagaag cagttcgtat ccaatacggc
    53521 ggttctgtaa aaccagaaaa tattgctgaa tacatggcaa aagaaaatgt tgacggtgct
    53581 ttagtcggtg gcgcaagctt gcaagcagat tcattcttgt cattgttaga cgctgtaaaa
    53641 taattgttga aaatttgcga aaaatgcaag aaatgtttgc actaatgagc aaaattaact
    53701 aaaatcgtat atgagggaaa tcccttagga aaaaacaaac tcaaaggaga gacaaaacat
    53761 gtcaattatt actgatgttt acgctcgcga gatcttagac tcacgtggta acccaacaat
    53821 cgaagtagaa gtatacacag aaagcggagc ttttggccgc ggaatggttc cttcaggtgc
    53881 ttcaactggt gaatacgaag cagttgaatt acgtgacgga gacaaagctc gttatggcgg
    53941 taaaggtgta actaaagctg tcgacaacgt aaacaacatc attgctgaag caatcattgg
    54001 ctacgatgtt cgtgaccaaa tggctatcga caaagctatg atcgctttag acggaactcc
    54061 taacaaaggt aaattaggtg cgaacgctat tttaggtgtt tctatcgctg ttgcacgtgc
    54121 agctgctgac tacctagaag tacctttata ccactaccta ggcggattca acacaaaagt
    54181 attgccaaca ccaatgatga acatcatcaa cggcggatca catgctgata actcaatcga
    54241 cttccaagaa ttcatgatca tgcctgttgg cgctccaaca ttcaaagaag ctctacgtat
    54301 gggtgctgaa gtattccacg cattagcttc aatcttgaaa gctcgcggat tagcaacttc
    54361 tgttggtgac gaaggtggat ttgctccaaa ccttggttca aacgaagaag gttttgaagt
    54421 aatcatcgaa gcaatcgaaa aagctggcta tgtacctggt aaagacgttg ttcttgctat
    54481 ggatgctgct tcttcagaat tctacgacaa agaaaaaggt gtttacgtac tagctgactc
    54541 aggcgaaggc gaaaaaacaa ctgacgaaat gatcaaattc tacgaagaat tagtttctaa
    54601 atatccaatc atctcaatcg aagatggatt agacgaaaac gactgggacg gattcaagaa
    54661 attaactgac gtattaggcg acaaagttca attagttggt gacgacttgt tcgtaacaaa
    54721 cactcaaaaa ttatctgaag gtatcgaaaa aggaattgct aactcaatcc ttatcaaagt
    54781 gaaccaaatc ggtacattaa cagaaacttt cgaagctatc gaaatggcta aagaagctgg
    54841 ctacacagca gttgtatctc accgttctgg tgaaacagaa gattcaacaa tctctgatat
    54901 cgctgttgca acaaacgctg gccaaatcaa aactggttct ctatcacgta ctgaccgtat
    54961 tgctaaatac aaccaattac tacgtatcga agaccaactt ggtgaagttg cagaatacaa
    55021 aggtttgaaa tctttctaca acttaaaaaa caaataattc ttttctaatg aagatacatg
    55081 atcgactatt gaaagatagt cgagtatgat cacttagtta agtaatcgaa ctctctactt
    55141 gctgaaatat cagcaggtag agagtttttt tgcaactagc ttctgtatat gatgttt
//
LOCUS       DADQCX010000007        54894 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.007, whole genome shotgun sequence.
ACCESSION   DADQCX010000007 DADQCX010000000
VERSION     DADQCX010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 54894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.007"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            445..1152
                     /locus_tag="J8R83_000369"
     CDS             445..1152
                     /locus_tag="J8R83_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9573531.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1211..1855)
                     /locus_tag="J8R83_000370"
     CDS             complement(1211..1855)
                     /locus_tag="J8R83_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAZ9573532.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            1981..2268
                     /locus_tag="J8R83_000371"
     CDS             1981..2268
                     /locus_tag="J8R83_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573533.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2376..2696
                     /locus_tag="J8R83_000372"
     CDS             2376..2696
                     /locus_tag="J8R83_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9573534.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2777..4090
                     /locus_tag="J8R83_000373"
     CDS             2777..4090
                     /locus_tag="J8R83_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9573535.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            4087..4806
                     /locus_tag="J8R83_000374"
     CDS             4087..4806
                     /locus_tag="J8R83_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAZ9573536.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            4934..5485
                     /gene="raiA"
                     /locus_tag="J8R83_000375"
     CDS             4934..5485
                     /gene="raiA"
                     /locus_tag="J8R83_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAZ9573537.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5707..8241
                     /gene="secA"
                     /locus_tag="J8R83_000376"
     CDS             5707..8241
                     /gene="secA"
                     /locus_tag="J8R83_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAZ9573538.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            8367..9468
                     /gene="prfB"
                     /locus_tag="J8R83_000377"
     CDS             join(8367..8429,8431..9468)
                     /gene="prfB"
                     /locus_tag="J8R83_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAZ9573539.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9573..10259
                     /gene="ftsE"
                     /locus_tag="J8R83_000378"
     CDS             9573..10259
                     /gene="ftsE"
                     /locus_tag="J8R83_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAZ9573540.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10243..11136
                     /locus_tag="J8R83_000379"
     CDS             10243..11136
                     /locus_tag="J8R83_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573541.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11288..12736
                     /gene="cls"
                     /locus_tag="J8R83_000380"
     CDS             11288..12736
                     /gene="cls"
                     /locus_tag="J8R83_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAZ9573542.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13073..13930
                     /locus_tag="J8R83_000381"
     CDS             13073..13930
                     /locus_tag="J8R83_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAZ9573543.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            14045..14965
                     /gene="pstC"
                     /locus_tag="J8R83_000382"
     CDS             14045..14965
                     /gene="pstC"
                     /locus_tag="J8R83_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAZ9573544.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            14965..15849
                     /gene="pstA"
                     /locus_tag="J8R83_000383"
     CDS             14965..15849
                     /gene="pstA"
                     /locus_tag="J8R83_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAZ9573545.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVSEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15864..16670
                     /gene="pstB"
                     /locus_tag="J8R83_000384"
     CDS             15864..16670
                     /gene="pstB"
                     /locus_tag="J8R83_000384"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573546.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16686..17444
                     /locus_tag="J8R83_000385"
     CDS             16686..17444
                     /locus_tag="J8R83_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573547.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKNKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17457..18134
                     /gene="phoU"
                     /locus_tag="J8R83_000386"
     CDS             17457..18134
                     /gene="phoU"
                     /locus_tag="J8R83_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAZ9573548.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18371..19402
                     /locus_tag="J8R83_000387"
     CDS             18371..19402
                     /locus_tag="J8R83_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAZ9573549.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            19399..20166
                     /locus_tag="J8R83_000388"
     CDS             19399..20166
                     /locus_tag="J8R83_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAZ9573550.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            20266..21834
                     /gene="liaX"
                     /locus_tag="J8R83_000389"
     CDS             20266..21834
                     /gene="liaX"
                     /locus_tag="J8R83_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAZ9573551.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22134..22451
                     /locus_tag="J8R83_000390"
     CDS             22134..22451
                     /locus_tag="J8R83_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAZ9573552.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            22451..22801
                     /locus_tag="J8R83_000391"
     CDS             22451..22801
                     /locus_tag="J8R83_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAZ9573553.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            22968..23906
                     /locus_tag="J8R83_000392"
     CDS             22968..23906
                     /locus_tag="J8R83_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAZ9573554.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            23921..24751
                     /locus_tag="J8R83_000393"
     CDS             23921..24751
                     /locus_tag="J8R83_000393"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAZ9573555.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            24795..25820
                     /locus_tag="J8R83_000394"
     CDS             24795..25820
                     /locus_tag="J8R83_000394"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAZ9573556.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            25835..26773
                     /gene="galU"
                     /locus_tag="J8R83_000395"
     CDS             25835..26773
                     /gene="galU"
                     /locus_tag="J8R83_000395"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAZ9573557.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            26898..27338
                     /locus_tag="J8R83_000396"
     CDS             26898..27338
                     /locus_tag="J8R83_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAZ9573558.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            27341..27943
                     /locus_tag="J8R83_000397"
     CDS             27341..27943
                     /locus_tag="J8R83_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAZ9573559.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(28002..29108)
                     /locus_tag="J8R83_000398"
     CDS             complement(28002..29108)
                     /locus_tag="J8R83_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAZ9573560.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            29318..30319
                     /gene="ccpA"
                     /locus_tag="J8R83_000399"
     CDS             29318..30319
                     /gene="ccpA"
                     /locus_tag="J8R83_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAZ9573561.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(30656..33001)
                     /locus_tag="J8R83_000400"
     CDS             complement(30656..33001)
                     /locus_tag="J8R83_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAZ9573562.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            33280..34182
                     /locus_tag="J8R83_000401"
     CDS             33280..34182
                     /locus_tag="J8R83_000401"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAZ9573563.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            34395..36170
                     /locus_tag="J8R83_000402"
     CDS             34395..36170
                     /locus_tag="J8R83_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAZ9573564.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(36236..37822)
                     /locus_tag="J8R83_000403"
     CDS             complement(36236..37822)
                     /locus_tag="J8R83_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAZ9573565.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            38073..38297
                     /locus_tag="J8R83_000404"
     CDS             38073..38297
                     /locus_tag="J8R83_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAZ9573566.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            38439..40190
                     /locus_tag="J8R83_000405"
     CDS             38439..40190
                     /locus_tag="J8R83_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9573567.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            40190..41974
                     /locus_tag="J8R83_000406"
     CDS             40190..41974
                     /locus_tag="J8R83_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573568.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            42300..43151
                     /locus_tag="J8R83_000407"
                     /pseudo
     CDS             42300..43151
                     /locus_tag="J8R83_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            43205..44956
                     /locus_tag="J8R83_000408"
     CDS             43205..44956
                     /locus_tag="J8R83_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9573569.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            44960..45130
                     /locus_tag="J8R83_000409"
     CDS             44960..45130
                     /locus_tag="J8R83_000409"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573570.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(45170..46072)
                     /locus_tag="J8R83_000410"
     CDS             complement(45170..46072)
                     /locus_tag="J8R83_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9573571.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            46303..47706
                     /locus_tag="J8R83_000411"
     CDS             46303..47706
                     /locus_tag="J8R83_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAZ9573572.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            47706..49139
                     /gene="ascB"
                     /locus_tag="J8R83_000412"
     CDS             47706..49139
                     /gene="ascB"
                     /locus_tag="J8R83_000412"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAZ9573573.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            49284..50210
                     /gene="trxB"
                     /locus_tag="J8R83_000413"
     CDS             49284..50210
                     /gene="trxB"
                     /locus_tag="J8R83_000413"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAZ9573574.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            50424..52151
                     /locus_tag="J8R83_000414"
     CDS             50424..52151
                     /locus_tag="J8R83_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAZ9573575.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            52223..52516
                     /locus_tag="J8R83_000415"
     CDS             52223..52516
                     /locus_tag="J8R83_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAZ9573576.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(52608..53468)
                     /locus_tag="J8R83_000416"
     CDS             complement(52608..53468)
                     /locus_tag="J8R83_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAZ9573577.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            53560..53988
                     /locus_tag="J8R83_000417"
     CDS             53560..53988
                     /locus_tag="J8R83_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAZ9573578.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            54150..54326
                     /locus_tag="J8R83_000418"
     CDS             54150..54326
                     /locus_tag="J8R83_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAZ9573579.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            54353..54799
                     /locus_tag="J8R83_000419"
     CDS             54353..54799
                     /locus_tag="J8R83_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAZ9573580.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        17835 a         9598 c        11744 g        15717 t
ORIGIN      
        1 attctgctga tttaagatag agttaagtta actacaagaa ttggagggat ccacatgaaa
       61 tggaaagaaa aagtagacga agcagctgaa aagttatatg atttggtcaa atcagaaaaa
      121 tacaatattg aagtgaatat tccgaaaaaa ggcggaaaag cggtccgggt aaaatcaaaa
      181 cgcccaacga atcatacaaa aaaatggatg gctaaaaacc gctaataata acaaaagatc
      241 cataagtcgg cattttcatc gattttaggg tcttttgtta ttttctaggt tggacatatc
      301 taaaaaattg tttctgacaa taggagtagg aagaacgatg tgtgtctaaa tcctctgttg
      361 atggatagaa acctttatct ttttcagttg tgaatcaggt atataccagt tataatagaa
      421 gaaacgaaag gacgggtgta cgttatgtcg aatcaattac ctgtatatat acagattcat
      481 gaccaattaa aaaatgaaat cgaacaaggt atatggaaag tcggagaccg tcttccttca
      541 gaaagagaat tagcagtgaa attcaatgtc agccgtatga cgttgagaca agcaattcaa
      601 aacttggcag atgaaggaat cttagaaaga aagatcggtt cgggtacata tgttgcacga
      661 gaaaaagtac aagaaaaaat gtctggtgca acaagtttta cagaaattat ggaatcacaa
      721 aatcgagtac cgtctagtcg gacaatctct tatttcttga cttcgccaag ctcaagtgaa
      781 atggaaaaac taaacttgag taaagatgac acgatcttgc gaatggaacg tattcgtttc
      841 gcagatgatg tccctatttg ttttgaagtt gccagtgtgc cacaaaagct gatcgatggc
      901 tacagcaaag cagagattac tgaatcgttg tatcgcacgc tagaagaaaa aggcgggaaa
      961 aagatcggtc cagcgaatca aacgattact gctgtgttgg cttctgagaa aattgctgac
     1021 tatttagagg taaaacgagg agatgcagtt cttcgtttgc gccagatttc ttattttgaa
     1081 gacggtacgc cgtttgagta tgtgcgtacg caatacgtag gaaatcgttt tgagttttat
     1141 ttggaaaaat aaaaaacagg tgatccctga ttccgtatta gaaataaaag agaatcagaa
     1201 tcacctgttt ttatatatga tcagttacca gttgctcgtg ataagaaaca ggaccctctt
     1261 caaattggac ttgtccgttc agcagctcaa tgatggattc tttaaagtgg tcagcacttt
     1321 tttcatctac agcacagatg acgctaactt gatcagtata ttggatttct tttataaaaa
     1381 aatgttggag ttcaagataa ttctgtaatt ttcctagttg cggatacgtg atcatcacag
     1441 agatctcctg ttgcaaggta ccttctacga ttccaatgtc agacaatgct tgagagaccg
     1501 catgagtgta tgctcgtatt aatccgcctg tgccgagttt cgttcctcca aaatatcgag
     1561 tgactactgc agctacattg atcagttgat tttttttgag gacttccaac atcggtatgc
     1621 ccgccgttcc acttggttct ccatcatcgc tgcttcgctg gatttcattt ttttctccaa
     1681 tgatgaaggc gctgcagtta tggttcgctt tccaatgttc tttttttatt tcttgaatga
     1741 aactttttgc ttcgtcctct gattctattc gtctaagaga acagataaag cgtgattttt
     1801 tgatctcgat ctcactttgt ccattttctt ttattgtacg atagcgctcg atcatcttgt
     1861 cacctctttt ttcattttct ttattcagta taaataaagt tctaggttgt ttcaacactg
     1921 taacggttgc gcaattgctg tagtatgcga taataaagac aaaggcaggt ggatctgggg
     1981 atgcaggaac gaatgaaaaa gtacgatgca attacgcatt atttgaagaa caatggcggc
     2041 tctcaagtaa cgttgacctt tacccaattt gacgaactgc tgtttcccag taacggactt
     2101 cccaaaacag caagggaaag tacagattgg tgggcaaatg attataaaca ccctgaaaaa
     2161 ggtgcctatg gctggataaa tgcaggctat gaagtagttg tcatcaattt ggacaaagaa
     2221 tatgtcgtgt tcaataaatt agtgaaatct agttggctat ttgattaaat aaaccgcgtt
     2281 tagaaaacgt tgacaaattt ctttcttttt atataataga gtaacagacg cgaagaaaac
     2341 gtttgcgtag tttgttttaa aaaggagaga aaagtatggc taaaaaaaca atcatgcttg
     2401 tatgttcggc tggtatgagc acaagtttac tagtaacaaa aatgcaaaaa gctgctgaag
     2461 caaaaggaat cgactctgat attttcgctg tgtccgcttc tgacgcagat aacaatcttg
     2521 caaataaaga cgtggatgtg ttgttattag gcccacaagt tcgctttatg aaagctgatt
     2581 ttgagaaacg tctggaacca aaaggcattc ctttagatgt catcaatatg gctgattatg
     2641 gtatgatgaa tggcgaaaaa gtgttagatc aagcaatcac gctcataggt gaataaatag
     2701 aacagtataa ctatcgaaca agcgatccaa aaaatagatc gcttgttttt tcgtatattt
     2761 ttttagggcg aataatatga atcatttttg gggtagaagg cttctgacga gagatattaa
     2821 agcaatagac tgtgaggagg taaatttacc aaattatgag aagatcgcag cagtggaacg
     2881 tttgagcaac tggattcttt gtcatcgctg tggaatgaga acgtccgtca ttgatggaca
     2941 gcttgcagat tacggttatt tttgtacaca ttgtctatat ttagggcgat gcgacactca
     3001 acaagattta tatttgtttg atcagcctga agcaaaacct cgagaagtcg tctttttttg
     3061 gacaggacag cttactgaaa aacaaacgga aatctcaaag agaatacttt gccattcaga
     3121 aaaaagacat catcttattt gggctgtaac aggtgcaggg aaaacagaga tgctttatcc
     3181 tattttagtg gaaactttaa aagctggagg aagagtagcg atttgtacac cgcgagtcga
     3241 tgtttgtaat gaattgtttt tacgctatcg ttatgttttt ccagaagaaa aaatcacgtt
     3301 gctccatggg aatacagcaa cggcttatac ctttacttct tttgttatct gtacgattca
     3361 tcagctatac cgtttttatc ggtcctttga tttaatagtg atcgatgaga tcgatgcgtt
     3421 tccttataac ggggatgcag gattagctca tgctgtgcaa acagcgatta aaccagacgg
     3481 acgattcatc tacttaagtg ccacacctga taaaaagtta ctaaaggaga tcaagcagac
     3541 gtttgacatc cacaaacttg ctttacgctt tcatcggcgt ttgcttcctg aacccgtctt
     3601 ggttttcatg aataattggc gacaaaaatg caagaacaag aagaagataa aatctttggt
     3661 gcggatcatt catcaattaa ttaaagaaaa ccatatcctt ttattttgtc caagtatcac
     3721 gatgatgcat cgtttgaaag ccacacttca agaggctctt ccgagatatg agatcacaga
     3781 tgtttcttca agagacaatc agcgggcgga aaaagtccag aaaatgcgag aagcaaaata
     3841 tgacatactg ttaaccacga tgatccttga acgtggagtc acatttgaaa gaatatccgt
     3901 tatcgtttta ggagcggatc atccggtttt tactaaatct tctttggtac aaatcgcagg
     3961 aagagccgat cgtaaagggc cttatacgaa cagtcaagta tattttttct atgaagaaaa
     4021 aactgcagct attcgaaaag cttgtcagga aatcaaagaa atgaatgaag aagggaagaa
     4081 gatactgtga ggtgcagttg ctgcagtaaa gatatcgtcc aaaatttaac attcagcgag
     4141 attattggtg tttcgaaata cagattacct cagacttgtt cagtttgtcg cgcacaattt
     4201 catttattgg aaacaagagg ctgttctggc tgtcaaaaac caatccattt caatctagag
     4261 agtacgaaaa agaaagtaaa ttctatcccc gtttactgca gtgactgtca agaatggaag
     4321 aagaaatatc cgacctatga ttttcagcac cgtgcctttt ttgtgtacga tgaaaatatg
     4381 aaggcctggc tcaatcaata caagtttatg ggagatatcc gactagcagg cacctttgca
     4441 tataaatgga cgcagataaa aaaagaatac ccgacataca tctattgtcc aataccttta
     4501 tctgaaaaaa ggcgaacaga aagaggattc aatcaagtaa gcgagatgtt gaaagcagca
     4561 agaattcctt ttcagatgct actcaaaaga gagaagcatc tgctggctca agcaaaaaac
     4621 acgcgaaagg aaagattgga gatgcctcaa ccttttgaac ttgcagtcac cttttctaag
     4681 atacaaaata aaaaaatatt gattattgat gatgtctata caacaggaca gactcttttc
     4741 cacgcagcag attgtttgca gatcgcacag ccgaaaatca tccgaactat ttctttggcg
     4801 agatgaatta gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat
     4861 ataatagaat taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa
     4921 aggggtaatt tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc
     4981 gattcgcgac tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc
     5041 cgatgcaacg gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt
     5101 aacgatccca ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc
     5161 aagtatcgat ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat
     5221 taatcgtaaa tcccgtgaaa cgggcatgaa tactgcaaat gctgctgctt tattcaatga
     5281 agaggacgaa aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt
     5341 gaaaccaatg gatagtgaag aagcagtctt gcaaatgaac atgctgggac ataacttctt
     5401 tatttttgaa gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa
     5461 atacggactg attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc
     5521 agctactgac agctgccgca agtttttttg agtttcctcc tcttttagat gaaatatgaa
     5581 taaattatga agttcttact ttaatacgct taagatattt caattatcta taactaatga
     5641 taaaatgaaa agtaaagtct acatagtctg gataatacac agaaggaaaa ggagattaca
     5701 caacgcatgg ccaatttgat tcgttcactt atcgaaaacg ataagaaaga actaaaacgt
     5761 ttagatagca ttgcaaaaaa agttgaagca tacgctgacc aaatggcagc attaactgat
     5821 gaacaattac aggcaaaaac tgctgaattc aagggcagat accaaaaagg agaaacatta
     5881 gatcaattac ttccggaagc ttttgcagtc gtccgagaag cagcaaaacg tgtattaggt
     5941 ttatatccat accacgtaca attgatgggt ggaatcgtgc ttcacgatgg aaatatccct
     6001 gaaatgcgta ctggtgaagg taaaaccttg accgcaacga tgccagtata tctaaatgct
     6061 ctgactggcg aaggggtaca cgtagttacc gtcaatgaat atttagcaac ccgtgactcg
     6121 acggaaatgg gcgaacttta taatttctta ggattaacag tggggttgaa tatcaactca
     6181 aaatcttcgg atgaaaaacg cgaggcttat aattgtgata tcacttatag tacgaataat
     6241 gaattaggat ttgactactt gagagacaat atggtcgttt accgccatca aatggtacaa
     6301 cgtccgctga attatgccat tgtcgatgaa gttgactcaa tcttgattga tgaagcgaga
     6361 acgccgctga tcatttcagg gcaagcagaa aaatccacag ctttatatac aagagcagac
     6421 aacttcgtga aacgtttgaa agaagaagaa gattataaaa tcgatgtaca atcaaaaaca
     6481 atcagtttaa ccgaagcagg gatcgaaaaa gcagaagaaa cattcggttt ggataactta
     6541 tacgacattg aaaatactgc attgacccat cacttggatc aagcattgag agccaactat
     6601 atcatgcttt tagatatcga ttatgttgtc caagacggaa aagtactgat tgttgaccag
     6661 ttcactggtc ggatcatgga tggacgccgt tattcagatg gacttcacca agcaatcgaa
     6721 gctaaagaag gcgtagagat cgaagacgaa acgaaaacca tggcgacgat cactttccag
     6781 aactatttcc gtatgtacaa gaaacttgcg ggaatgactg gtacagctaa aacagaagaa
     6841 gaagaattca gagaaattta taacatccaa gtataccaga ttccgacaaa tcgtccggtt
     6901 atccgtgatg atcgtccaga tttgctttac ccaacattac aaagcaagtt ccacgctgtc
     6961 gtgcaagata tcaaagatcg ctaccgcaaa ggtcaacctg tgttagtcgg aactgttgcg
     7021 gttgaaacat ctgagttatt atcagatatg ctgaatcaag aacgtattcc tcatgaagtg
     7081 ctgaatgcga aaaatcactt taaagaagca gagatcatca tgaatgctgg tcaaaaaggt
     7141 gctgtgacga ttgctaccaa catggctggt cggggaacag atatcaagtt aggacttggg
     7201 gtaagagaac ttggtggtct agcagttatc gggacagaac gacatgaatc tcgtcgtatc
     7261 gataaccagc ttcgaggacg tgcaggacgt caaggagacc ctggtatgtc acagttctac
     7321 ttgtcattgg aagatgattt gatgaaacga ttcggttcag aacgaatcaa agctttctta
     7381 gatcggatga agatcggtga ggaagatgct gttatccaaa gcaagatgct gacgaaacaa
     7441 gtagaatctg cacaaaaacg tgtagaagga aataactatg acacacgtaa aaacgtctta
     7501 caatacgatg atgtgatgcg tgaacaacgt gaagtaatct ataaacagcg acaagaagta
     7561 atcatggaag aaaaaagctt atccaagcca ctaatgaaca tggtcaaacg gacaatcagt
     7621 cgtgtagtag atgcgcatac acaattagag aaagaaaatt ggaatttgga aagtatcatc
     7681 gattttgccg gcagtactct tgtccatgaa gatagtatta ctcttgcaga tatcgaagga
     7741 aaaacagctc aggagatcaa agagtatcta aacgaacgag cacaagaagt atttaatacc
     7801 aaagcggctc aactaaatgg tccagagcaa ctgttggaat ttgaaaaagt cgtgatcttg
     7861 cgtgttgtgg actctaaatg gacagaccat attgacgcaa tggatcaatt acgtcagtca
     7921 atcggcttac gtgcttatgg acagaacaat ccattagtcg aatatcaaac agaaggctat
     7981 aagatgtttg aagatatggt aggcgccatc gagtatgaag tcactcgaat ctttatgaaa
     8041 gctgagatcc gtcaaaacgt acagcgtgaa caggtttctc aaggaacagc ttctcactca
     8101 gaagacggag atgccaaaga aaatagtaat actagcgcga aaaaacagcc aatccatgtg
     8161 aacaaggtcg gaagaaatga tccttgtcct tgtggaagcg ggaaaaaata taagaactgt
     8221 catggaaaaa atgcaaacta atttctgaca gcaggattgg tgagacaaat tcttttttta
     8281 agaattcgtc tcaccttctt tctgttattt gctgattctg ttagactaga tataatgaaa
     8341 aaagtatagt gaaagaagga aaaaacatgg aaatatccga aattcgaaat ctcctgacag
     8401 aaatgcagga aaaggtcaca agtttcagga ggtctctttg acttagatca gctggaagaa
     8461 gacatcgcgg aagcagaagc aaaaatggct gaacctggtt tttgggatga cagcgaagcc
     8521 gcacaaaaag tgatcagtga aaataacgct aataaagaaa cctatgacca attccattct
     8581 cttgccgaag aactagaaga aatcgaattg atggtggaga tgctgcaaga agaacctgat
     8641 gcagcaatgc aagaagaagc agaaacacgt atcaatgcat tagatgaaaa aatgaagacg
     8701 tatgaattat ctatgctgtt agacggacct tatgatcgaa acaatgcgat cgtcgaattg
     8761 catccagggg ctggcggaac ggagtcccaa gactggggca gcatgctttt acgtatgtat
     8821 acacgttggg cagagcagca tggctatcaa gtagaaacac tagattatca agcaggtgat
     8881 gaagcaggga tcaagagtgt gaccctgctg attaaaggac ataacgcttt tggttatcta
     8941 aaatcagaaa aaggtgttca tcgccttgta cggatttcgc cttttgactc agcgaaacga
     9001 cgtcatactt ctttttgttc ggtagatgtg atgccagagc ttgatgaaac gatcgatata
     9061 gaaatcaatc cagatgattt gaaaatcgat acgtaccgag caagtggtgc aggtggtcag
     9121 cacatcaata aaacagaatc tgctgtacgg atcactcact tgcctacagg aacagtagta
     9181 gctagtcagg cacaacgctc acaattgaaa aaccgtgagc aagcgatggg gatgttaaaa
     9241 gctaagcttt atcaattaga agtggaaaag aaagaacaag aagcagctgc acttcgagga
     9301 gaacaaaaag aaatcggctg gggttcacag atccgttctt atgttttcca tccctattct
     9361 atggtaaaag accatcggac aaacgtagag acaggaaatg tccaagcagt tatggacggt
     9421 gaccttgatt tatttattga cggctattta aaaatgcatc tacaataaga acccattgtt
     9481 aaattgaaat aaaattgtaa gattttgcaa gcatgttgaa acattgccat gctataatag
     9541 ctaaagactg aaaaagatat ggagagaacg ccatgattga aatgaaggat gtaatgaaga
     9601 agtactcaaa tggtacgacc gctatccgca atctctcgat tgtcatcgaa caaggagagt
     9661 ttgtctatgt ggttggtccg tctggagccg gtaaatctac attcatcaaa ttgatgtatc
     9721 gagaagaaaa agcttcaaaa ggaactttga acgtcgcagg tcatgatcta atagcaatca
     9781 aaaaccgcga agttccttat ctacgcagag aaatcggcgt ggtgttccaa gactataaat
     9841 tattaccaag aaaaacagta tatgaaaatg ttgcgtacgc tatgcaagtt atcggcagaa
     9901 aacctcgaga tatcaaaaaa cgagtaatgg aagtgctgga ccttgttggt ttgaaacaca
     9961 aagttcgagt ctttcctagc gaattatccg gtggggaaca gcaacgtgtc tctattgctc
    10021 gggcaatcgt gaatacgcct aaagtactta tcgcggatga accgacagga aatctggatc
    10081 cagaaaactc atgggaaatc atgaaattat tagatcggat caatgcccaa ggaactactg
    10141 tcgtgatggc tacacataac agtacgatcg taaatacgat tcggcaccga gtaattgcta
    10201 tcgaaaacgg ccgcattatt cgagatcaag cggaagggga atatggatac gatgattaga
    10261 acctttttcc gccatttatt agaaagtatc aagagtttga aacgtaacgg ctggatgaca
    10321 gttgcttcag tcagtgcggt aacgatcacg ttgactttag tcggtgtatt catggcagtt
    10381 atcatgaatg caactaaatt agctcaggat atagaaggaa acgttgatgt atctgtattc
    10441 gtagatatcg gtacaaaaga cgaagagatg aaaaagctag aaaaagaatt gaatgactta
    10501 gatcatgtta aaaaagttga attttcaagt aaagaacagg aattgaaaaa aatccaaaac
    10561 gaaatgggtg attcctggaa attgtttgaa ggtgacaata acccgttata tgatgtgtat
    10621 gtagtaagtg ctactgatcc ttcttataca aaacaagtag cagaagaagc agcagatttg
    10681 aagaatgttt ctcgttctga ttacggtgga gcttcctcag atcggatttt ccaaatcgct
    10741 ggtgcagttc ggacatgggg attagttgca gcggcattgc tgctgttcgt agcgatgttt
    10801 ctcatttcga acacgattcg gatcacgatt ttgtctagac agcgtgaaat tcaaatcatg
    10861 cgtttagtcg gtgcaaaaaa tggatatatt cgctggccgt ttttccttga aggtggctgg
    10921 atcggtctga tcggtgcgat tcttccgatt ttgatcatca catttggtta tgcatggttt
    10981 ttccaattga tcaatccatc attattacgt tcccattatt cattgattca tccacaaaat
    11041 atcgtttgga aaatcaatct tttaatggtc ggcattggtg tgatcattgg ttcacttggc
    11101 tcgatcattt ctatgagacg tttcttgaaa ttctaatacc acaatataaa taaaatgaga
    11161 aagttggaca gtttcgttcc agctttcttt ttttattggc taggagaata gaaggaagcg
    11221 gcttttttcc ctttacttta aaaaacaact tgggtattct taagttggta gaggaagagg
    11281 tgaagccgtg aaaattatcg ttgacaattt ttttacgatc cttttgatta tgaatatttt
    11341 gctttccttt atcatcgttt ttcgagaaag aaaggaaact gctcaaacat gggcatggct
    11401 gctcgttttg atgttcattc cagttgtagg atttatttta tatatttttt taggaagagg
    11461 gatttccaaa gagaaaatct ttgatttgaa gatccaaggg aaaatcggta agaacctgga
    11521 aattgaagaa gacaaacagg cattgatgcg agggctttat cctcatccgc ctactggaca
    11581 agtagatgtg aaacaattga tctatatgct cacggtattt gaaagtacgc tctatacgac
    11641 taaaaatgaa atcactttat ttacagatgg tcgtgaaaaa ttcgatgcgc tgattgaaga
    11701 tatcaagcaa gcagaagacc atatccactt ccagtattat atttatcgca gtgatgcatt
    11761 aggtgaagaa gttcgagatg cattgacaga ggcggcaaga cgaggggtaa aagtcagagt
    11821 ccttcttgat gcatggggtt ccacacaagt ttcttccagc ttttttcaga atttgaaaaa
    11881 agcaggcgga gaaatcgcat ttttctttcc tctatttgtt ccgtatatta atcctcggat
    11941 caattatcgc aatcatcgta aaatcgtagt tattgatggg aaaatcggat atacaggtgg
    12001 gttcaatgtt ggaaatgaat atctaggatt ggtaaagaaa tttggttatt ggcgagacaa
    12061 tcatttgcgt atttacggag aagcggtgta tatcttgcaa aaccgttttt tgatggactg
    12121 gaattctcag catacaaaag aagtaggcta ttctcccaaa ttttttccgt ccattcactc
    12181 tactggtgat atagctgttc aaatcgtgac aagcggacca gataccgaac atgaacaaat
    12241 caaaatgact tatttgaaaa tgatttcgtt agccaaacgg gagatattga tccaaacgcc
    12301 ttattacata ccggatggat cgattcatga agcactgaag ttggctcttc tttcaggcgt
    12361 aaaagttcat atccaaatac ctaacaaacc agatcatctt ctcgtttact gggcaacgta
    12421 ttctttcgct gcagagctga tcgagtatgg agcaaggatc gaaacatatg agaatggatt
    12481 tattcatgca aagacgatga ttatcgatgg tggcattgtt tcagttggct cagcaaatat
    12541 cgatgttcgt tcatttcgct tggactttga ggtcaataca ctgatttatg atgaacgaat
    12601 ggcttcacgt gtaagaaaag cattttttga agactcgaaa atttctacgc atctcacaaa
    12661 agaaatgtat gaaaaccgag gaataatcat caagatgaaa gaaggattag caagattgat
    12721 ttcgccgctc ctttaaaaca caaaaaggac atgagaacca tcaacagatg gagatctcgt
    12781 gtccttttct aacggggcca tttctgagag tacgtcagaa atggagaaag cgtctcgcat
    12841 gagcgaaatt aactttgggg tatctcttgt tttttgggga aagcaagaaa taagctaata
    12901 tatgctatta aaagagacac atttcaaagc cagtatagca tagaaacttt taatgagata
    12961 gtttttttta caattatgag gatttatttt gttatttaat gattttgatt cgttttcatc
    13021 aagtaatgaa aatgataaaa taaacatact ttaggattaa aggagatttc taatgaaaaa
    13081 acttaaatta ttcttaccaa taataggatt agctattctt ttatcaggct gttcaaagtg
    13141 gattgatcga ggagaatcca ttacggctgt tggctcttct gctttacagc ctttagtaga
    13201 aacagttgct gaaacttacc agacagaaaa tcctggaaaa ttcatcaatg tacaaggggg
    13261 cggaagcgga actggtttgt ctcaagtaca gtcaggagca gtcgacatcg gaaactctga
    13321 tttgtttgcg gaagaaaaat cggggatcga tgcctcagca ttagtcgatc atcgagtagc
    13381 agttgttggg atcactccta ttgtgaacaa ggatattggc gtaaaagaca tcagtatgga
    13441 aaacctgaaa aaactattta caggcgagat caaaaactgg agtgaagtcg gtggaaaaga
    13501 tcagccagta gttatattga accgtgcttc aggaagcgga acccgtagca cgtttgaaaa
    13561 atgggtattg gacggagaaa cagctgttca ggcacaagaa caagattcaa gcggaatggt
    13621 gcgccagatc gttgccgaca cacccggtgc aatcagctat gttgcttttt cttatgtttc
    13681 cgatgatgta gatacgttga atgttaacgg tgtagaaccg acagatgaaa atgtgacaac
    13741 gaacaaatgg acgatttggg catatgagca tatgtacaca agagatcatc caaaaaaact
    13801 gacaaaagaa tttttagact atatcttatc tgatgaagta caagataaca tcgttggaga
    13861 actaggttat atccctgttt ctcatatgaa agtcgaacgt gattggcaag gaaatatcgt
    13921 taaagagtaa tctttacaca aaatttacaa acttagctaa acttttacat gttattaaaa
    13981 ccaaattgat gttcaatttg tacactgagt gagtatgtta aacctgatta agggggagtc
    14041 atctgtggaa gatgtgaaaa aagtattatt aacaaaatca aaacgttcaa aaatggaaca
    14101 gcgtggaaaa ttcatcagtt ttttatgtat cgcgctgatc gtgttggttg tattatctat
    14161 tttttatttt gtagctagta aaggattggc cacctttttt actgataaga tcaatgtatt
    14221 tgattttctg tttggtacag attggaatcc aagccaaatc ggagcaaatg ggaaaccaat
    14281 ggtaggggca ttgcctatga tcacaggttc gtttattgtg acctttttat ctgctattgt
    14341 tgccacacca tttgccattg gtgcagcagt attcatgacg gagatctctc ctaaaaacgg
    14401 aacgaagatc ttacagccgg tcatcgagct gcttgtaggt attccttctg tcgtttatgg
    14461 ttttatcggt ttatcagtta tcgtgccttt tgtcagaagt atttttggcg ggacagggtt
    14521 tggtatctta gctggtacat ttgtgttgtt cgttatgatc ttgccgactg tcacaacgat
    14581 gactgttgat gcattaaagg cagtaccacg gcactatcgg gaagcttcat tagcgcttgg
    14641 tgccacaaga tggcaaacaa tctacaaagt cgtgctacga gcagccgtgc ccgggatttt
    14701 aacagcagtc gtttttggta tggctcgtgc gtttggtgaa gccttagcta tccaaatggt
    14761 catcggtaat gcagcattga tgccaacagg acttactact cctgcttcta cattgacgtc
    14821 catcttaaca atgggaatcg gaaatacaat catgggaaca gttgaaaata atgtgttatg
    14881 gtcattagcg ctgatcttgc tattgatgtc attattcttt aatatcgtga tccgtatgat
    14941 tgggaagaaa ggagagctga aataatgaac gcaaaacgct cagataaaat tgctacaggt
    15001 gttttatatg tagtttcggg gatcatcgta ttgattttag cagctttact actttatatc
    15061 ttagttcggg gaataccgca catttcatgg tccttcttga ccgaaccttc caaagcctac
    15121 caagaaggcg gtggaatcgg gatccagcta tttaactcga tttatttgct tttgatcacg
    15181 atgatcatca gttttcctat ttctttaggt gcgggtatct atctttcaga atatgctgga
    15241 aaaaactggc tgacagatgt gattcgcacg tcgattgaaa tcttgagctc attgccttct
    15301 gtcgttgtcg gtttattcgg tttcttggtt ttcgttattc aattccagta tggtttctcg
    15361 attatttctg gtgcattggc tttgactgta ttcaacttgc ctcttttgac tagaacagtt
    15421 gaggagtctt tacaagcggt ccattacaca caacgagaag caggattggc tttaggtttg
    15481 tcacgctggg aaacagtgat aaaagtggtg gtttcagaag cgacaccagg gattttgact
    15541 ggtgtgatcc taagttctgg aagaattttt ggtgaagcag ctgcattgat ctatacggct
    15601 ggacaaagtg cacctgcgtt agattttacg aactggaatc cattaagtgt ttcaagcccg
    15661 atcagcattt tccgtcaagc tgaaacatta gctgtccata tttggaagat caatacagaa
    15721 ggcacgatgc ctgatggtgt ttctgtttcg gctggcgctt ctgccgtgtt gatcattgct
    15781 gttttactgt tcaacttcgg cgctcgtgcg attggcaaac gattataccg aaaaatgact
    15841 tcagcctaag gagaagaagc aaaatgaaaa aatataactg gaatgaaaca aatgtcatca
    15901 ccatgccaaa agagaaagaa gtagcactat atacggatga tctacatgtc tggtatggcg
    15961 acaatgaagc aatcaaagga gtggatctgg aatttgaaaa aaataagatc actgcactga
    16021 ttggtccttc cggctgcgga aaatctacgt atcttcgttc gttgaatcga atgaatgatg
    16081 ggatcgctaa tacgaaaatc actgggaaaa tcatgtatca aggcgtagat attaatgcgc
    16141 ctcaagtgga tgtttatgag atgcgcaaac ggattggcat ggtttttcaa cgtcctaatc
    16201 cgttcagcaa gtcgatttat gacaatatta catttgcttt gaaacagcac ggcgaaaaaa
    16261 acaaaaagaa attagatgaa atcgttgaaa caagcttgaa acaagctgcc ttgtgggacc
    16321 aagtaaaaga cagcttggac aaaagtgcct tggctttatc tggcgggcaa cagcaacgtt
    16381 tatgtattgc tcgtgcgatc gcgatgaaac ctgatatctt gctgctagac gagccggcaa
    16441 gtgctttgga ccctatttcg acaggaacgg ttgaagaaac acttgtaaac ttgaaagaag
    16501 actatacgat catcatcgtg acgcataaca tgcaacaagc ggctcgtatc agcgactata
    16561 ctgccttttt ctatctagga aaagtaatgg aatatgacaa aactaacaag atatttacca
    16621 gaccaaaaat tcaggcaacc gaagattatg tgtccggtca ttttggttaa gacggaggcc
    16681 tcaacatgac aaaagaaatt atttcatcta aagatcttca tctgtattat ggaaagaaag
    16741 aagcactaaa agggatcgat ctaagtttca atcaagggga aatcactgcg atgatcggtc
    16801 cttctggttg cgggaaatcc acttatctgc gttctttgaa ccggatgaat gacctgattc
    16861 cgaatgtaac gatcaccggg agtgttttat ataaagacaa agacatctat ggtccaaaaa
    16921 cagatgttgt tgaactaaga aaagaaatcg gcatggtatt ccagcagcca aacccatttc
    16981 ctttttctat ctatgaaaat gtcatctatg gattgaaatt aaaaggggaa aaaaataaaa
    17041 aagtccttga tcaagtagtt gaagaaagcc tgaaggcagc gtctgtttgg gatgatgtga
    17101 aagacaaatt gcataaaagt gctttatctt tatccggtgg gcagcagcag cgtgtatgta
    17161 tcgcacgtgt tttggcagtt aatccggaaa tcatcttatt ggatgaacca acaagtgcgc
    17221 ttgatcctgt ttctactggg aaaatcgaaa gtatgctgtt agaattaaga gagcggtata
    17281 cgatgatcat cgtgacccat aatatgtctc aagcttcacg tatttcagat aagacggcat
    17341 tctttttaga tggtcacttg atcgaataca atgatacgaa gaagatattc atgaatccag
    17401 aaaaacaaga gacagaagat tatatttcag gtcgatttgg ataaggagga aacggaatgc
    17461 tacgtacaca atttgaagaa gaattgctga atctccataa tcagttctac gaaatgggga
    17521 tgatggtgag cagcgccgtg cacaagtcag ttcgtgcata catcaaacac gataaaatct
    17581 tagcccaaga agttatcgaa aacgatataa atatcaataa catggaaaca cgcttggaga
    17641 agaaaagttt tgaaatgatc gcattgcaac agccagttac aactgatttg cgtatgatca
    17701 ttacggtcat gaaagctagc tcggatttag aacgtatggc cgatcatgcg gtgtctgttg
    17761 ctaaatccac gattcgcgta aaagggcaga cgagaatacc ggaaatcgaa aaagagatct
    17821 ccgatatgtc cgattatgtg aaaaaaatgg tggacaacgt cctagttgct tatgtcaaaa
    17881 cagacgaaaa agacgcacgt acgatcgcca atatggatca aagagtcaat gactatttca
    17941 atcgaatcta taatgcaaca atcaaaaata tgcaggaaaa tcctgagaca gtcatcagtg
    18001 gaacagacta cttgaatgtt gccagttatc tagaacggat cggagactat gtgacaaaca
    18061 tctgtgaatg gatcgtctac ttggctacag ggaaaatcac tgagttaaat acgaaccaca
    18121 atgagatttt ctaaactaaa gcggtgattc tgccgtttgt ttaggaaaag aggttgtgaa
    18181 atcagcggtt gtgaaaaagc tgttctgcat caagtaataa gaacagtcaa acaaaaatag
    18241 ctcctcatat ttttcatttg gctggactta ttaccgcaga tgcaagcttt tgaacactgt
    18301 ttattcggga aagggtttgt gacaaaatat gtcacaaacc cttttcatca tttcatagaa
    18361 aggataaaga atgcaaaaaa aaattagcat catcactata ttttttattt gtgtgcttac
    18421 ttcatgggtt attcagcatc aagctgcttt atatgaagta cctgtcatcg agatcgaaaa
    18481 agtacgaata aaagaggatc atcaattgat tacaggaaga ctgatgaaca cgaatcaaaa
    18541 aggagaatcg atttatttat cggttcctta tcaaaaaaat caaatagaaa cagcaaatat
    18601 aaaagcgaga caaatgtatc tagtccaaat gcatggagat gaatggcagc tagtagcaaa
    18661 aaaaaatgat ggctggcttt tcttcttcac aagtatcttc attggcgcca tgttgcttat
    18721 tggcggaaaa catggtctat ttgctttagg aagtctcatc atcaatatcg ttttactttt
    18781 acttttgttg ctcatcttta ctaaaataga agggatttct ctattaaata tatctatcct
    18841 gttcgtcgtt atagggatga ttattagcat attggcttta gatggatgga atagaagcag
    18901 tataatcaaa atttcagctg cagttacgag tgttttttta gcatttttta tttgtctttt
    18961 gacaatgaat ctttggaaag accaaggact gcgctatgag gaactgaatt atctgacacg
    19021 accgtatcgt tctgtttttc tttctagcgt actgattgga acagctggag gaacactcga
    19081 taccgttatc acagtcattg cgacattaga agaattgact aagcgacaac cagaaataac
    19141 agcgaaacag ttatggcttt cgggaaggca agtgggtcga gatgtgattg gctcgatgac
    19201 caatatcctt ttgttcgtct atatcagtgg gtcagttcca tcgcttcttt tatatttagg
    19261 aaatcaatgg tcgttcaaag aaacgataga acagcattta tcattggaat ttttacgcgt
    19321 cattgctggc agcttaggaa tagtattatc gatccctatc tcggtcctct tttttctgac
    19381 tgtaaggagg ctgaaacgat gaatgtactt attatacttg ttgggatttt agcaatcagc
    19441 gtgctactta ttggcggtac gcaaggtatg tatattcttt taggcttatt catcaattta
    19501 gggatctttt tcttgttgtt attcggttat catcagaagt ggccgatact ggcattgtcg
    19561 gtcataggat ttttattgat tgctgtggtt atcttatttt ttatcaacgg ttataatcta
    19621 aaaatgcgtg cagcttttgt gagtatactg atctttttat tttgtttcct actattgctt
    19681 cctatcactg attttttagc aatccaaggt tttacaacga tagaactaga agaattatct
    19741 ggcttagata agactttagc gattgatttt agattactta cgagatcgtt gcttctgatt
    19801 agtcttagtg gtgctgtttt agatgcgagt gtagcaattt ctagtgggac attcgaagta
    19861 tatcaggcaa atccgcaatt atctttttac caattgcgcc attctagttt cgctattgct
    19921 aaaaaaatat tggcgtcaac agtaatgaca cttctttttg cattcatggg aagttcttta
    19981 gcgttgatcc tctggtttat tgatttagac attccttttc agcaagtgat caatgaaaaa
    20041 tcatttgttc tagaatatac gatggctatt cttaccacat tgtccgcact acttgttctt
    20101 cctttaacct gcgtgactac agcatatctc tttacaaaaa agaaagaaca actcaagatg
    20161 gagtaaaagt tacaacttaa gtcctatgac atttttactg aatcagtgca taatatggat
    20221 gtaaggaaaa gcttgcaaac aattttgctt aaggaggcaa tttccatgaa agaaagagaa
    20281 cgtattttag atttagtgaa aaaaggaatc ctttcgactg aagaaggctt agatttatta
    20341 gaaagcatgg caactgaaaa agacgaaaag caaatcaaaa aagaagcaga caaggtaact
    20401 gctagtcata aagaaaaaga tcaggcaagt caattgatcg ataaacttga aaacggcgaa
    20461 gaagaaattt ctgagccagt tgatccaaag gaaagagaaa gacaagatca agaaaactta
    20521 gaaaagatct tagatgaact agcaactgaa gcgaataaaa cttcggcgcg tctagatgaa
    20581 gtaaatgctc aattcgctga caataaggca gcacgcaatg agaaacagga agcattgatg
    20641 cagctgaata caaaagaaga attaggcgag ttgacagaag aagaattagc acagcgtcag
    20701 acgttagaag cagaaatcaa agagttagaa gctagtggcg atacactgtt agaagaacaa
    20761 ttgaaattag aagcagaatt aaaagatatc cgtaagaatc aatggtctga gaaaaaagaa
    20821 acgtttactg ataagtttga attgccagat gattggaaag atcaagcaac agatacactg
    20881 aatcaagtag gcgaaaaaat gtcagaagct ggatcacagt taggaaaatt cttgaagaaa
    20941 acattccaaa ctgtttcaga aacagtgaat gacaacatgg aatggaaaga tgtcagcttg
    21001 cgtgttcctg ggattgcgac aacgaaattt gagcatgaat tttactatga agctcctgca
    21061 gcaagtatcc ttgatatcaa ggcagcaaac ggaaacgtga cgttaaaaac gtgggacagc
    21121 aacgatgtga aagttgaagc taagatcaaa ctttacggaa aaatgggtgc tgaaccattt
    21181 gaagcattct ctgaacggag ccagattgag gttaatgaag atcatatctc cttccaaatt
    21241 ccaaataaac gtgtgcgtgc agaccttgtt ttctacttac ctaaacgagt atacgaccac
    21301 gcagctatta aacttctaaa tggcaacatc atgattgaaa cattggaagc taaagatatt
    21361 tatacaaaat ctacgaatgg taacatcatc gtggaccaat taactgcaac gatgctggaa
    21421 gtagaaggtg taaacggcaa tatcgatatt cgaaacggga acatcttaga ttctattatc
    21481 gaaacagtaa atggtacagt gacatttggt gcgacagcag aaaacctttc tgtgtctttg
    21541 gtaaatggtg atgtacgtct tacgattaaa gaagataatt tgaaaaaagt agaagcaagt
    21601 tcagtgaacg gaaatgtcaa agtcgcttta ccagatggca tcggtttgga aggacatgct
    21661 aaaacaagtc ttggaagtat caacagccgt ctgtccaatt acgaagtagt tcgtgagaaa
    21721 aaagaacgga caaaccaaat gttgcaattc cgtcgtgttt cagatggtga aatcgcgcaa
    21781 gtgcaacttt caacgacaac aggaagtatc tatttaaaag atacagataa ataaagaggt
    21841 tgtgaaagag atgttcagcc ttgagcaata agaagcgatt ttgtaaaata gcttccccta
    21901 ttttacaaaa ttgtgcctta ttgccgatag gctatctctt gaacaccgtt taccaagaga
    21961 ttatgaactt gccaattatc gccgagtcac aaggaataat ttcaaaaaaa gctcgtcacg
    22021 ttttatgaat atggtaattt gtgaccgaga attttgcaaa aagacaccga ttaagaagaa
    22081 ggttgtcaca acgattttct tcatttaaaa tagtagaaca gaggtgagac atgatgaaaa
    22141 aaaagttgac aaaatccaat aaaaatgttg ttttgacagg gactttagca ggaataggag
    22201 aatacatcgg gattgatccg actgttatcc gtgtgcttta tgtattcctg agcttagttg
    22261 cttttggaag tccaatcatt ttatacattt tattagcttt gattatccca tctgcgcgtt
    22321 ctgcacgaac aaactatgga cataacaatg catattatga aaaaaacaat tatcgtgaac
    22381 aaactcgtga acaaacaaaa aaacgcaaag aagcggaaaa aatcgatgat gacgaatgga
    22441 gtgactttta atgtcgtact ttcaacgtat tttagttaat acgttaacat tcatatcatt
    22501 ggctgttctt tttcctgcga tggtccatgt gagcagtatt tggacggccg ttcttgccag
    22561 cttcgtattg tctgtgttga atatgtttgt caaaccgatt ttgacgatac tgtccctgcc
    22621 ctttacatta gtcacattgg gattgtttac gtttgttatc aatgcagcga ttcttaaaat
    22681 gacctccttt tttgtgggag cagaacattt tagtttttct tcattcggtg cagcgttgtt
    22741 agtagctatc ttgatgtcgc ttgtcaatgt aattgtcagc gaacataaca gtagaaaata
    22801 aaagaaagct gtgccgaact atcggcgcag tttttttatt tagaatcagg aatgcgtttt
    22861 ctattacatt ggtaattaaa taaaaacgtt ttttttaatt ggtagtactt ttggctagac
    22921 aatgataaaa tgatagagaa cactctaata gaaatgaggt agcatgaatg tcagaagttg
    22981 taaaagttag ccaattagtg aaaaaattat ctttggaaat cgtgacaggc gacgagaaaa
    23041 gcttagaccg tgtcatcgta actggggaca tctcacgccc aggactagag ttgactggtt
    23101 attttaatta ttattcccat aatcgtttac agctatttgg cagtaaagaa atcagttttg
    23161 cggaacggat gatcccagaa gagcgtttga tcatcatgag aagattatgt agtgaagata
    23221 tgcccgcatt tattatttca agaggattac cagctccaga agaaatgatc caggcagcaa
    23281 atgaaaatgg gatagctgta ctgcgttctc ccatctcaac ttctcgctta ttaggagaat
    23341 tatccagtta tttagatggt cgccttgccc ctcgaacaag tgtccacggt gttttagtgg
    23401 atgtttacgg attaggtgta ctgattcaag gtgacagtgg gataggaaaa agtgaaacag
    23461 cgttggagtt gatcaaacgc ggtcatcgat tgatcgcaga cgatcgagta gatgtttatc
    23521 agcaagatga attaacggtg atcggagaac cgcctaaaat cctggaacat ctgattgaaa
    23581 tccgaggaat cgggatcatt gatgtaatga atctttttgg tgcgagtgcg gtacgtggct
    23641 ctatgcaagt ccagttggct gtttatctgg aagcatgggc aaaagataag aaatacgacc
    23701 gtctgggctc tgaagacacg accgttgaaa tcgcggaagt aggcattcca caaataaaaa
    23761 tccctgtcaa aacaggacga aacgttgcaa tcatcattga agtagccgcg atgaatttcc
    23821 gtgcacgtac aatgggcttt gacgcaacga aaacatttga agaaagatta agtcgcttga
    23881 ttgaagaaaa ctcaggcaac gactagcaag gagtgacaat atgttagcac aaatcaatcg
    23941 agttgctttt gagcttgtag ggattcctat ctactggtat gcattgatca tcgtatcagg
    24001 tatcattatc gccatgtggc ttagcagcag agaggctgtt cgggtaggat taaaagcaga
    24061 tgatgtgaca gattttatgt tgtggggatt gcctatctcc attattggcg ctcgcttata
    24121 ttatgtttta tttgatcttc cccagtatat agctgatcca atccaaatat tcaatatccg
    24181 ttcaggaggc ttagctattt atggcggact gattgcaggc gcgatcacgc tgtatttttt
    24241 tactaaatat cattttattt ctttgtggac ttttttagat atcgctgcac caagtgtatt
    24301 attagcacaa gcaatcggtc gttggggaaa tttcatgaac cacgaagcat atggaccaga
    24361 cacgacgcga agcttcttag aaagtctgca tttaccgcaa ttcatcattg ataatatgta
    24421 tatcgaaggg atctatcgtc aaccaacatt tctttatgaa tcactttgga gtttgattgg
    24481 atttattttg cttttgtttt tacgaaagaa accacacctt ttgaaaaaag gtgaagtcct
    24541 tttatgttat ctaatgtggt atagtttcgg gcgtttcttt attgaaggat tacgtacaga
    24601 cagtctttac tttttaggtg tgatccgtat ttctcaatta ttatctgctg tgttatttgt
    24661 cggtacattg attctattta tttggcgcag aaaaaaagga aatttaccgg attatgaccg
    24721 ctcattagga aaaaatcaac aaattatctg atttttagag cgttaaaaat gaaaaaaatt
    24781 tcaggagtgg taaaatgaat tatagagtag cggttttagg accaggctct tggggtactg
    24841 ctttggcaca agtcctcgcc gaaaacggac atgacgttcg gatttgggga catcgtgctt
    24901 cacaagtaga agaaatcaac acccaacaca cgaatcaacg ttatttacca gatcattgtc
    24961 tacccgattc catccaagca ttcaccaata tggaagatgc agtaaaagac gcagatgcgg
    25021 tgctattcgt cattccaacg aaagcaatac gttctgttgc aaaagaacta gtgcctaaat
    25081 tgaatacaaa gccagtgatc atccatgcaa gtaaaggatt agaacagggg acacataaaa
    25141 ggatctctga tatcttgtta gaggaaatcc cagtagaaaa aagaaaagct gttgttgttc
    25201 tttctggacc aagccatgca gaagaagtag cgaaacatga catcactacg atcacagctg
    25261 caagtacaga tgcaaaagca gcaaaatatg tacaagagct gttcatgaat aattattttc
    25321 ggatctatac caatcctgat gtgatcggtg tagagatggg ggcagctttg aaaaatatta
    25381 ttgctattgg tgctggcgct attcacggct tagggtttgg cgataatgca aaggcagcaa
    25441 tcatgacgcg cggattagct gagatcagcc gtttaggtgt agcaatgggt gccaacccgc
    25501 tgacctttat cggattaagc ggagtaggcg atctagtcgt tacttgcaca agtgttcatt
    25561 ctaggaactg gcgcgcaggc aacttgttag gacaagggca gcccctagaa gaggtgctag
    25621 ccaatatggg aatggtcgtt gaaggtgtga atactaccca agcagcgatg gaactagccc
    25681 aaataatgga aatcgaaatg cccatcactc aaacaatcta tgaagtgctg tatgaacaaa
    25741 aagaaatcaa aacagccgca aaagaaatca tgttacgtga tgggaaaaaa gaaaatgaat
    25801 tctcattaac aattttttga aggagcgaat gtatatgaaa gtcaaaaaag cagttattcc
    25861 agcagcagga ttaggaacaa gatttttacc agcaacaaaa gctatggcaa aggaaatgtt
    25921 gccaattgtt gataaaccaa caatccagtt catcgttgaa gaagcgttga aatcaggtat
    25981 cgaagacatc ttgatcgtta caggaaaagc taaacgacca atcgaagatc actttgattc
    26041 aaatattgaa ttagaaacaa acctaagtga aaaaggaaag accgaattat tgaaattagt
    26101 agaagaaacg acagatgtca acttgcattt catccgtcaa tctcatccaa agggtttagg
    26161 acatgccgtt cttcaagcaa gagcctttat tggaaatgaa ccatttgtcg ttatgctagg
    26221 cgatgatata atggaagacg aagtaccatt gacacagcaa ttaatcgatg attacgaacg
    26281 tactcatgct tctacgatcg ccgttatgca agttcctcat gatgaaactt caaaatacgg
    26341 aattatcaat ccaggagaag tattggaaga tgggttatac aatgtcaaaa actttgttga
    26401 aaaaccagat ccaagcaaag caccaagtga tttagctatt attggacgtt acttattgac
    26461 tccagaaatt tttgatgtat tgtccgagca acaaccagga gccggaaatg aaatccaact
    26521 aactgacgca atcgatacat tgaataaaac acaacgcgta tttgcccgta aattcacagg
    26581 taaacgttac gatgtcggtg acaaatttgg ttttatgaaa acaagtattg aatatggtct
    26641 aacacatcca gaagtaggtg cacctttacg tgagtacatc ctgtctttag gtaaaacatt
    26701 agaagcagaa ggaagcaaga tcgatcataa tccaaaagga ataacagaaa tcaaagaaga
    26761 aaagaaaaaa taaccctttt ttctaacgag cttcagctgc taattgaata aaaagtagtt
    26821 gaagctcgtt tttatttgtt taaaaaacac gaaaatgcta tccttataga aaagagagac
    26881 aagaagggag tttgatcatg tcaggaggag aaattgcagg attgatcgca gcaatcgcct
    26941 ttgcgatact tgtcgttttt atcgttcgtg tgttgttgca agtttctaaa actttagaaa
    27001 aagtagatca gactgtagca gaagcaaata cgacgatcga aatcgtcaca aaagacgtag
    27061 atcttttgtc tagacaagta gaaggcttac tggtcaaaag taatgaactg ctcttggata
    27121 tcaatggaaa agtcgcaacg atcgatccat tgttcacagc agttgctgat ttaagtgaaa
    27181 gtgtatcaga acttaatcat tctagtaaaa acatcgcgac gaaagtcggc ggaatcggta
    27241 aaacgacagc taaagcgacg gttgccggaa aagtcggtgg gacagcgatg aaatttttta
    27301 aaaacaaaaa acatactgaa acgacaggag gaaaataaaa atggctaaaa aaggtggatt
    27361 tttattaggt gcagtagtcg gaggcacagc cgcagcaatc gccgcgttat tgttagcacc
    27421 aaaatctggt aaagaacttc gggatgaatt agctgcccaa gcggatgatt tgatggatat
    27481 ggcttcagat tacacagata tggcgaaaga aaaatcgact gagttaacag gtattgcaaa
    27541 agaaaaagcg caagatcttt ctcaacaagc aggtgatcta gcaggtagtg tcaaacaaaa
    27601 agtaagtgaa tcagcagatg aagcaggaag tgaatctgac gatatcttgt taaatcttaa
    27661 agaacaatca gctgacttat ctaatcgttt caaaaaaacg gcagaagata tgaaaaaacc
    27721 tgcagatgaa ttaggaagta ttgctaaaga tacttcagaa gatatcatga ttgatgtaaa
    27781 agacgctgct ggtaaagcag gagatactgt caatgaagga atgtcagaag caaaaccagt
    27841 tgcagatgac tcaaaagaaa tgatgaaaat ggcaaaagaa gatgcgaaag aagctaaaaa
    27901 agaaataaaa gatacaatga cagattcatc tacaaatcac taaaatcaca aatttataga
    27961 ataaaaaggt gggagcggac tagctctcac cttttttact cttatttttc taaaacaagt
    28021 aattcttttg gtgtagtcgt gaatggcaca cagccatcgc ttgtcacata tacacagtct
    28081 tcgatacgta cccctacttt ttcaggaata tagattcctg gttcaagaga gaagcacatc
    28141 ccttcttcga ttactaagtc atttccttct acaagggaag ggaattcgtg gacggttgtt
    28201 ccgatcccgt gacctaaacg gtgattgaaa tattcgccgt agccatagct gttgatcacg
    28261 tttcgtgcga tttgatcaag ttcacctgct gtcacacctg gacggacggc ttcttgtgcg
    28321 gcaagctgtg cttcaagagt gatgttgtag attttttctt ggaagtcggt tggtttttga
    28381 taagcaattg tacgagtagc atcactgcaa tagccattcc aaacaacgcc aagatcgaat
    28441 aacacaagtt cattcggtga aatcttcgta tttcctggtg taccatgagg gcttgcagca
    28501 tttgctcctg caaggactaa tgtgtcgaaa gacatttgtg aaacaccttg ttttttcaat
    28561 tggtattcaa tttctgcaat gatcgcttgt tcagtcacgc cttctttcac tgctttaaag
    28621 ccaatctcaa atgcaacatc ggcccattta ccagcttcga tcagtttgtc tttttcctct
    28681 agagttttga tcagttgtag acgttggatg atggaagtta gatcagtgta agaatccgtt
    28741 cccgtcaaga tatcagagat agcatcgaag cgctcgacag tcaaggcgtt cttttcaatc
    28801 cctacattgc caggctgacc atagcgagca cgaagttctt ttccgatgat ctcccaaggg
    28861 ttttcgctgt ctaaatagcc acggacatca tacgcccaac tactgttttg agcatcttca
    28921 acttccaaag caggagtgaa aaggaaagga tcttgttcaa gagggataaa aagagctagt
    28981 acacgctcat gaggatcact ttcgtatccg gaaaagtaag cgatgtggcc agggtcgctg
    29041 atataagcca attcgacttg gtgttgtgcc atccattgac gtagttcatt gatttttacg
    29101 ttattcattt ggcaacctac tttctaaatt aattttgtat tcaataattg taccactgat
    29161 ttattaaaag accaacgttc taaaaactga aaaaagtaaa aattttcatg aaaacagaga
    29221 taaaacggtt gcaattcttg agattatttg atattctatt ttagaaatgt aagacgtatt
    29281 ttcagaaaac atataaaata tgaataggag aacacaaatg gaaaagcaaa caatcactat
    29341 ctatgatgta gcgagagagg caaatgtttc gatggctact gtttcacgtg tcgtaaatgg
    29401 caatccaaac gttaaaccag caacaagaaa aaaagtcttg gaagttatcg atcgcttgga
    29461 ttatcgtcca aacgcagttg cgcgtggctt ggcaagtaag aaaacaacaa cagttggtgt
    29521 aatcatccct gatgtcagca atatgttctt tgcttcttta gcacgtggta tcgatgatgt
    29581 ggcaacaatg tacaaataca atattatctt agcaaattca gatggcaacg accaaaaaga
    29641 agtcaatgta ttgaataact tactggctaa gcaagtggac ggcgtgatct tcatgggtca
    29701 ccatatcaca gacgaaatcc gtggagaatt ttcacgttca aaaactcctg ttgtattagc
    29761 tggctctatt gatccagatg aacaagtagg tagcgtaaac attgattatg tatccgcaac
    29821 aaaagatgca gtaaacaaat tggcaaaaag cggcaataaa aaaatcgctt ttgtcagtgg
    29881 tgcgttgatc gatcccatca atggacaaaa tcgtctgaaa ggctataaag aagcattaag
    29941 cgaaaataac ctaccatata gcgaaggatt gatctttgaa gcacaataca acttcaaaga
    30001 tggtctatct ctagtcgatc ggatccataa tagcggtgca acagctgtct atgtttcaga
    30061 tgatgaatta gccatcggta ttttggatgg tttattagac cgtggcgtga aagtaccgga
    30121 agaattcgaa atcatcacaa gtaacaattc actactgaca gaagtagctc gtcctcgttt
    30181 aacaagtatc acacaaccat tatacgattt aggggctgta tctatgcgcc tattgacgaa
    30241 aatgatgaat aaagaagaag tcgaagaaaa aacgattatc ttgccttatg gaatcgaaga
    30301 aaaaggatct acaaaataat aaaaggacaa ccattcagag gttgtgtgcc tgccgtttaa
    30361 ctctgcgtta caaggagcaa tttcaaaaaa cagcatctca tgtttgatga atattgtgac
    30421 tcgtgattcg gagttggcag gagaacaccg tttatttggg aaaaggggtt atgacaaaat
    30481 tttgttataa tccttttttt gtgtcttaaa aaagagagaa agtggttgaa attacattta
    30541 tcgtatataa aacaatccgt gtatagatgc tgcattttgt tcaccaccat caaaaaaata
    30601 agggactgtg acaatactat tgtcacaatc ccttattact gtgtattcta ttaaatcaat
    30661 catctttctc atctgattct ttagttgctt gattcgctct tgcataagct gaagcggtgt
    30721 tccagtaatc tgtatagttt tcatcggtac cgccaacgcc aaatttaaag gcgcttttct
    30781 tcggtccatt tttcgcccat agcgattcaa ctgtttttcc tggtgtttgg atggattttt
    30841 tattgacagt aacttttcca ggtgtttgac cagtaaatcc agatactttt ttcttcatca
    30901 catcagatga taattcgaat ttctcatcag tgccaaaaat gtcaggtttt gcttggtaag
    30961 cttgattgat cagattggca agataattag ccgaacgtat ccttgctttg ctgtccattc
    31021 cagtattgtc atcgtgccct gcccagctac tgatggtaat agacggagta gagacaatta
    31081 gccatgaatc tcggtattca ttggtagaac cagtttttcc gacccaatct gcttttccta
    31141 gatttccgtt taagcttgag atggcatctt tgaatggtgt agtgattttt gcattgatca
    31201 cactacgcat catgtcattc atgatcgatg ccgttgcttc cgaatagatc cggacagagt
    31261 tgctttcgtg tttataaatt acatttcctg cgttatctgt gatggaatcg atgatatagc
    31321 cttcttcata gacgccgccg tttgctaaag cctgaaatcc gttggtctgt tgaagcgtcg
    31381 tgacatctac tgtacctaaa ggagcagatt caacgcccca attgtcattt gccgggtagt
    31441 tcatctttgc caagtagtgc tcgtaagcat attgtttcga tccaccggaa ttcaacacat
    31501 cttgatataa gtgataagcc gggatattgt tggaccattc tagtgactca cggacggttt
    31561 ggaaggtgtt cgatccttcg ttagtagcat tgacgatttt ctcgccagca ttttctcctt
    31621 cttgccaagt tgttgcataa tctgatacac gggattctga tccgataagc cccatgtcga
    31681 ttgcaggtcc ataaacaaga actggtttga ttgatgagcc agcttgacgt tctgtatcga
    31741 aggcatggtt attttgattc tgactgtaat tccgtccgcc aacgaatccg tagatgcggc
    31801 cagttctgtt atccatcaat acatttccgg tttctacttg actgccagca ccatcatcta
    31861 acatgtatcc ataattttca acgccatttt gcaatgcagc atagacatct ttatcgattg
    31921 tcgaatggat tgtatatcct ttattttgga tcgtttgctg tgccttttga taataagcgt
    31981 cactgaccga tgaatcagac atatcagcgt tgtctttttc agccaattgt tgtgcaatga
    32041 ttcttgttgc ttcattcatc acagtataat acaagaattc tctgtcagtc tgttctgcga
    32101 tttgttgtgg tagaaagtct tttgtaaggt cataggcttt tgcttcttcg tattgttctt
    32161 tcgtaatttg gccttcacga tacatactga ataaaacaaa atcttttctg gcaaggccgg
    32221 cagaaagatc ttcttttagc gcgcctgtgt tcgtgtatgg actatacgtg atcgggcttt
    32281 ggggtaatcc agcgatataa gcagcttgcg gcagcgtcac atcttttgca tctacaccaa
    32341 agattccttt tgcagcttcc tggactccag caatgttttg tcccttatta ttacgaccaa
    32401 atggtgagac attcaaatac gtagcaatga tctcatcttt tgaaaagtat ttttctactt
    32461 gtgcagaaag aatgatctcg tttgctttac gtttgaatgt tgtttcatct gtaaggatct
    32521 gctgtttgac taattgctgt gtcaaagttg atccaccaga agagccaata ccagtagctt
    32581 cagatactaa tgctcgtaaa acagctttag gaacgtaacc ttggtgttta tcgaagtatt
    32641 catcctctgt gctgataatt gcagttttca ataaaggtga aatcttatca gatgaaatag
    32701 tcgtgcgcat cagatctgtc tggatttttg atatctctgt attatctgca taaacaatct
    32761 ttgacgtttc tgtaatgttt cctagttctg tctgcagtgc ttttttagtc ggcaattgtg
    32821 tgtcttcgac gagataggca aaatagccag cgcctattcc aatacctaga gctgcgaaca
    32881 tcaaaagaag aacagtaata aaaacagtca atgattgaaa aactctaaaa ataatcttag
    32941 gaacaaacca tttttctttt tttcttctat tctgtttttt tcgagtattt ttgcgtggca
    33001 aaagggtcac ctcaactaat ggttttattt cgctaattat agcaaataat agaacaaaaa
    33061 aacagacaag gctgtttttg gcaggaattt cttttttaaa agagttaaaa cgtgagaaaa
    33121 tgatctttat tataaaagag ttcttaagct tttctttaga gaaaatttca gttactatgg
    33181 agaacagggc aaagaaaaat caatcatttt ctttgtatat catcttacca atatatagga
    33241 attgttagta acaattgcct ttcaaggagg aatccatcca tgttattagg ctcacacgtc
    33301 agcatgagcg gaaagaaaat gctgttagga gcagcagaag aagcagccag ttatggatct
    33361 tcgactttta tgatctatac aggcgcccct caaaacacta gaagaaaagc catcgaagag
    33421 atgaatattg atgccggaaa agcgtacatg gcagaaaaag gtctaacaaa tatcgtcgtt
    33481 catgcccctt atatcattaa tttggggaat acgatcaaac cagaaatgtt tccttttgcc
    33541 gtccaatttc tgagagaaga gattgttcgt gcggaagctt taggcgctac tcaaattaca
    33601 cttcacccag gtgctcatgt aggggcagga acagaagccg gaattgctag aattattgaa
    33661 ggcttgaatg aagttttgac aaaagaacag acggcacaaa tcgctttgga gacaatggca
    33721 ggtaaaggta cggaaatcgg tcgaacattt gaggaattag cgcaaatcat cgatggagta
    33781 aaattgaatg aaaaattatc cgttactttt gacacctgtc atacgaatga tgccggttat
    33841 aatattaaag aagacttttc aggtgtaatg gaagagtttg ataagatcat cgggttagat
    33901 cggcttaaag tactccatat caatgattct aaaaatccgc aaggttcgca taaagaccgg
    33961 cacgccaata ttggttttgg aacaatcgga ttcgacacgc tgaataagat cgtccatgat
    34021 ccaatgtttg acaatatttc gaaaatcttg gaaactccct atgtaggcaa agataaaaag
    34081 aaagcttacg caccatatgg aaaagaaatc gccatgttca aagcgcaaac attcgatcca
    34141 gaagtgtttc ctgagttatt agcagaagaa gtgatactct aagattttct atctgacagc
    34201 agcaaaaaag gaccaggcac attgccttgt ccttttttgt ttaagaaaca aaggagtact
    34261 ttttgcagtc tttttcatca tgcatcttct cccccctctt tttaaattta gacaaacaag
    34321 gtatactggt agaaaagtaa aaaaacgaaa agtttcacaa gcaagtggca aaacgtgatt
    34381 ggaaggacga aaagatgctg aacactttaa aacccttgat caaccaacta aaaaagaaac
    34441 atacatactt tattcttggc atagccctat tatttacaat tattcgtttg tatttatata
    34501 gtaaagcaat ctatggaaca gacatgtcgg caacctatga tgaccagctg ctgattcgct
    34561 atgctcaaaa tattttggac ggtaaatggc taggggagta tacgactaca acactttcca
    34621 aaggaatctc ctacagctta tttttagtac ttgcacataa actgcatctt tcttatgcag
    34681 ttttgttcgg catgttcagt atttttgcca gtatattggt tgcactcgcg tttaaaccga
    34741 ttgtgaagaa caagtatctt cttttaagta tctattttta ttttttgttt tctccgatta
    34801 gttttacaca tgaatattcc actcgaacat atcgtaatgc cctcgtgatt ccggctgttg
    34861 agatcattat cgcttgttta ttagctattt attaccgcaa atacggttct agcagaaaat
    34921 tgctgccatg gtttttaggg ctttctgtcg cttttccttt cttttggttc attcgcgaag
    34981 attctatctg gcttcttcct tttactgtag tagctttggg tatcagtttc gtccagatct
    35041 tgctagggca agacttttct ttcaaagaag taaagaagtt aaaaaaacga ctctttcttc
    35101 tctcgaaacg ggaatggctg aaactttcat tgtttttact tcctatagtt ggcttttcca
    35161 tcgtctatca atggatcgaa tataaaaatg agacaacata cggtattgca accatcaatg
    35221 accgttccag tggagaattt ggacgtttga tgaaacaact gatccgaata gatgatgaaa
    35281 cgaacttgaa taaagaaaac agtgagatat gggtctcaca tgctgcacta aataaagcat
    35341 tagccgcatc tcctacattc catactgttt ctacccgtat tgacgaatta tatacgactc
    35401 acgcgtggac tcaaggtgga aaagtaaaag aattacccgg agatatcatc ttttgggcat
    35461 tgcgagatgt ggtaagcgaa tctggttatt accaaaacaa tgcaaaagaa accaatgatt
    35521 tttggaaaaa agtcaaccaa gaattagaag aagcctatca caagggaaca atcaaaaaga
    35581 aaaaagagtt ctatctgatg ggatcaggag atggaaagac gatgagtgat ctgccaatcg
    35641 tattcgattt ccttcaatca ggatacgctt atgcatggcg atataaagat ttccatcaag
    35701 gaggaaatta tagtttcgga acgcaagaac aagtcaaaca ggctcaagaa ttattaaacc
    35761 ttccgctaat ggagaattgg atcgatagta atgaaccgag aacacctaat ttccaattaa
    35821 caaaatcagc aaaagtcgcg aatgtcatca taaaaattta ccaagttctg gctattcccg
    35881 tgctgattgc ttcaatagca gggatattac ttatgatact aggaaccgta tttgcaaaag
    35941 ctgatcgtgc ctattatagt tcctctttga ttgtggtcac cggattaata ctgacacaat
    36001 tggtttttct tttcggtgtc tcatggtttt gttcttatgc gccagaaaaa aaggactatt
    36061 ttttaagtgt ctacactggt gcaggcgtgc cattaacgca attcatcgta gtaacaagca
    36121 tgctagtttt cagtaaatta aatctgaaaa aagctttatc ttctaaataa aaagaccctt
    36181 ggtagctaga tttttaacct aactatcaag ggtctttgtg tggaaaaatc agtttttatt
    36241 cgatttcttc taccgtttcc tgcaaaagct gttcatattt tttgtttcct ttatataaat
    36301 caccaatcgt ccatgccaac aggagaagga caagaacaat gattacataa gcgatgtgat
    36361 cagccaatgc tagttgagcg gaagtggctt gctcgccgaa gaaactttcg atctgtcctg
    36421 gtaatcctcg taagttcaag taagttagac taatcacaga gaaccagcca agaagtttta
    36481 cgatgaatga atttttaaat cggctaccca tctccgcttg gctgttggtc atcatcagta
    36541 aaggaatcat cgaaaacggc aacgcaaaag ccaagaacac ctgggattca ttcattaagt
    36601 tattcaaagc ggcatgttct tcgatcgttc cttttgtact tgtaaacaaa acacaaatca
    36661 atacaggaat cacagaaagc aatcgtgtga ccagtcttct tagccaaatc gggatacgca
    36721 tatggatgaa tccttccatg atgacttgac cggtcaacgt accagtaata gtagagttct
    36781 ggccagaagc aagaagtgct acagcaaata aagtggacaa gataccagat tttgctacag
    36841 caatcaaaat accattgctc atagctgatg gatcagataa agcttcatac agaccaaaaa
    36901 aggaaggatc ttggacagaa ccggttttga agacagcgac acccatgatc aatagcagtg
    36961 cattgactag aaaagccatt gacaactgga tattagaatc ccaagtagaa aaacgtacag
    37021 cttgtgctac atcttcttcg ttttggtgat cgatcttccg agtttgtgaa actgctgaat
    37081 gaagatataa gttatgcggc atgactgttg caccaataat ccctaaagct ccagtcagcg
    37141 gagtttcgcc gccgatgacc ggtgagtctg agaatgtatg actgttaggg ataaagccag
    37201 caaataaact gtgccaatct gggttagaca agccaacttg atagacaaaa acgaataaaa
    37261 tgacgaaaat taagcagaca accagtgctt cgatcttacg aaacccgact tttgtcagta
    37321 gtaagagaac gaaaacatct aatacagtaa taaagacggc aatcaccaat ggaatatcaa
    37381 aaagtaagta gagggcgatt gctgcaccaa tgacttctgc aatatctgtt gccataatgg
    37441 ctaattcagt caagatccat aaaatgacac ctaatgtctt acttgtgcgt gctcggattg
    37501 cctgtgccaa atccatttgg ctcacgattc ctaattttgc tgccatatac tgtaaaagca
    37561 tagcaatcag actagacatc aaaataactg acatcaataa atattggaaa ttttgtcctc
    37621 cggtgatcga agtagaccag ttacccgggt ccatataccc aactgctact aacgcaccag
    37681 gtccagagta agcaagaagt gttttaaaaa aacttttccc ctttggtaca tcaactgttc
    37741 catttacttc agctaaagat aaaccatttg tatgttcaat aagtcgatgc ttatgaaatt
    37801 gtttattgga ttgattattc aagaaaaaac cacctttcct atttatctac gattacattc
    37861 tacacctcaa aaagaaaaaa ttaaagaaaa agattcggta cgcctaattt tttttcatgg
    37921 cgcgtcttgc tagatgacga aagaaatttt gttctcctct aaaaaaacca ctattttttg
    37981 catgaaacta aagaatacgc ctttcttttt tcaataaact ttagtaaaat aagtcattga
    38041 gagcaattcg gaaatagaaa ggagagattt atatgttatc aacaggtatt gtcgtactta
    38101 ttgctattat tgctttgcta atcggcgcag taggtggctt tttcctagcg cgtaaatata
    38161 tgaaagacta tttagaaaaa aatcctcccg ttaatgagga catgttgcga tcaatgatga
    38221 tgtcaatggg gcaaaaacca tctgagaaga aaattcgcca gatgatgcag caaatgaaga
    38281 accaagggaa aaaataggtt ctgacccaac gactttttac gggctgattt tttcagtccg
    38341 ttttttattt cgtaatttgt tagactattc agattattca gcaaaaaaga caagcacaga
    38401 caatcctagg ctcttgataa agacaaagga ggagtaaaat gtcgattttt agaaaattag
    38461 gctggttttt tcgtcaggaa aagaaacatt atttaattgg ggttttctcg ctattcgcag
    38521 tggccttggt acagttagtt cctccaaaag tgattgggat catcattgat gagatcgccg
    38581 ataaaaattt atcaataaag atcattttcg ggtggatctt cctattgatt atcgctgctt
    38641 ttttacaata tctttttcgt tatatctggc ggacgaatat ttggggaagt gcagctcgat
    38701 tggagaaaga acttcggcag cagttattca aacattttac agaaatggac aatctctttt
    38761 accaaaaata tcggactggg gatttgatgg ctcacgcaac gaatgatttg aatgcgatcc
    38821 agaatgtagc aggagctggt atcttgacct ttgcagattc agtgattacg ggcggaacaa
    38881 cgatcattgc gatgattttg tttattgatt ggcgcttaac actgattgcg ctgattcctc
    38941 tgcctttgct ggccgtcact tcacgagtgc tggggtcaaa actccatgat gcttttcgtg
    39001 attcgcaaga agctttttct agtatcaatg ataagacaca agaaagtatc actgggatca
    39061 aagtcattaa aacatttgga caagaaaaag aagatctagc ggattttgaa gaaaagattg
    39121 aagatgcaat tattaaaaac aaacgagtca attttttaga ctccttattt gatccattca
    39181 ttaccttgat tatcggtctg tcttatgttg caacaattat tttaggtgga aagtatgtct
    39241 tggaaggcac gatctcgatc gggcagatgg tctcatttat tagttatatc ggtatgcttg
    39301 tttggccgat gtttgcgatt ggtcgattgt tcaacgtatt ggaaagagga aatgcttctt
    39361 atgatcgcgt caatgaactt ttgcatgaaa agacgcatat cgtggaacaa ctgggtgcag
    39421 tgcagacccc ggcaaaaggc gagctgaatg tagctatttc ctcttttaat tatccgaaag
    39481 aagaatcacc agcattagaa caaatcaagt ttgcgatcca agaaggagaa acattaggta
    39541 ttgttgggaa aactggtgcg ggaaaaacga cgatcatcaa attactgatg cgtgaatacg
    39601 atgattatca agggaaaatc caatttggcg gacgttcgat caaagaatat tcattgaatg
    39661 ctttattagg atcaatcggc tatgtgcctc aggatcactt cttgttttcg atgaccattc
    39721 gagataatat ccgtttttct aatccaaaac tttcagaaga agaagtagag catgcggctt
    39781 ctttagcatt tatcaacaat gaaatcaagg aattaccaaa aggttatgat accttagttg
    39841 gagaacgtgg agtctcttta tctggcggac agaaacaaag gatttcgatt gctcgagcat
    39901 tgatcaaaaa tcctgaatta ttaatattag atgatgcact ctctgcagta gatgccaaaa
    39961 cagaagaagc tatcttgcat aatttaaaag aaataagaaa agagaaaaca actatcattg
    40021 cagctcaccg tttaagtagc gtgatgcatg caaaagaaat cattgttgtc gatcaaggga
    40081 aaatcattga acgaggaacc catcatgagc tgcttgcact aggcggctgg tatgaacaaa
    40141 tgtgggagaa acagcaatta gaagcgaaga tagaaggagg cgaggcctga tggatgaaaa
    40201 ttatcaatcg gaatggacaa aatcgattcc acttaaagaa cagaaaaaga tcatcaaacg
    40261 actgatgaag ttcgccaaac cttttagaag aacgttcatc gttgctatct tatttgcgtt
    40321 tgctttgtct gtgatcaatg tcctattgcc aaggatcatc caaactttta tggatgatca
    40381 tctggctaaa cagtcggcta cgacacaagt tattttgttt tttgctggta tgtacttatt
    40441 tggagtcata gtaaaaagta tcatttggtt tttccaatgg tatttgtatt ccatggcctc
    40501 attgaagacc tatcagtata ttagggtaaa attatttgaa aagctgcata cactaggtat
    40561 gcgttatttt gatcagacac cggcaggatc aaccgtttct cgagtgacga atgacacaga
    40621 aacgctattt gaattttggt acgtcttttt gatggtattg actgggatct ttgcagtcgt
    40681 ttcttcattc cttgccatgt ttcaaatcaa tggagaaatt gccttgtgga ctttggtgtt
    40741 tttgccgatt ttaggaatcg tcatctggta ttaccagaaa ttcagttctc gtatttaccg
    40801 aaatatgcgg gaaaaattaa gtcagctgaa cacgaaattg aatgaatcga tttccggcat
    40861 gcgtattatc cagcagtttc gccaagaagc tcgtttagct aaagaatttg aacaagtgaa
    40921 caatgagtat ttagacacgc gttatgcgat gatcaaaacg aattcgattc tgttaagtcc
    40981 gatcatcaat tttctatatg cattggcgat tgcgttggtg ttgactttgt ttgggatcga
    41041 tgcgttgcat tctcccgtag aagttggact gatctatgca tttacgacct atgtccaggg
    41101 attttttaat ccaatgtctc aaatgatgga ctttttgagc atcttcacag atgggatggt
    41161 tgctggtagt cgtatcttga agattatgga tacggaagaa tatgcaccac aacaaaaccc
    41221 tggagcagat caaatgatta cttcaggtaa gattgagttt cgcaatgtaa gcttttctta
    41281 tgatggagag cacaatgtat taaacaatat ctcttttgtt gctaatccgg gagagaccgt
    41341 tgcattagtg ggacacaccg gaagcggaaa aagctcgatc atcaacgtat tgatgcggtt
    41401 ttacgaattt tatgaaggtc agatattgat tgatgatcat gacattcgag aatatccaat
    41461 ggaagagtta cgtaagaaaa tggggctggt cttgcaagat gctttcttgt tttatgggga
    41521 tatcgcagga aatattcgga tgatgaatcc agctatcaca gacgaacaga tacgccatgc
    41581 ggctgagttt gttcaagcaa acaaattcat cgatgaatta ccaaaaggat atcactcaaa
    41641 agtgatcgaa catggtgcca gctattctag tggacaacga cagctgatca cttttgcgcg
    41701 aacaatcgtg actgatccta aaattctagt attggatgaa gcaacagcaa atatcgatac
    41761 tgaaacagaa ggattgatcc aagaaggatt ggcaaaaatg cgtcaaggac ggacaacgat
    41821 tgcgattgcc catcggctgt caacgattcg agatgcagaa ttgattttag ttttagacaa
    41881 aggtcatata gtagaacgcg ggaatcatga aacacttcta gcgcaaaatg gtttgtatgc
    41941 agatatgtac aaactgcaaa gcagtggtat ataaaagatg ttgtgacagt agaattttga
    42001 cctaagcact agagtgaaaa taaaacatag cttctcatat ttttcatctg tgagagttag
    42061 tgtcgtagtc accagattta aaaaaagatt cgacagctag tcagaagtgc ctaatagcca
    42121 ctaagaaagc gttgacaaaa gcatttgctt tcgataatat aaagaaaacg atacaacttg
    42181 gatagtgatt gcctgatgca agctaaacct gatgagtctc ccatggtttc atggacggct
    42241 ttttgggttt ttctttttgt tttggataca gccctataca tcatggaaag gagcaaaaca
    42301 tgctgattga gaaagtactg aataacaacg tcgtaataac cagggatgaa agaaatcagg
    42361 aaatgatcgt gatgggaaaa ggtttggcat tcaaaaagaa agtgggtgac ccgatttttg
    42421 actcatgcat cgacaaaaaa tttcagttga caaatgacgg gctttcacaa cagttctaag
    42481 aattggcaca agcgattcct cttgagtact tagaaatttc ttgtgaaatc attgaatata
    42541 caaaagaggc tctacaagtc cagttgaatg attctgtgta tattgcattg acggatcatt
    42601 tgtatacggc tatcgaacgt cacaaaatgg gaatatttgt accaaatgta ttgctgtatg
    42661 atatcaaaca actatttcct aaagagtatg ccatcgggaa aaaaacagtg aagaaaatct
    42721 cggataaata ccacatcaag ttatcagaag atgaagccgg atttatcgca ttgcatttag
    42781 tcaatgcaca aggcattcaa agccagcaag acaataccta cctgtttact ataacaatac
    42841 aggatattct aaatatcgtc cgctattact ataagattac atttgatgaa gattcagtcc
    42901 atttttttcg attcgtcaca cacttacgtt tttttctgac acgcgtccta gatggagaaa
    42961 aatcagaagt gggagaagtt tctgaggaat tgtttcaggt tattcaaaaa aaatataagg
    43021 atacgtttgg ttgcgttgag aaaatagcag actttttagc cgagacgttc aactaccaga
    43081 tgtccacgga cgaaaaaatg tatttaacga tccatactgc gcgtttagtg catgagaatc
    43141 gttgtaaata aaaaaaggag gataaattaa caagaacgta tgaaataagg gtagtgacat
    43201 tcagttggct aaaccttcca ctaataaatt ggagggaata gaaatgggaa aataccaaga
    43261 attagcgaga aaaatcgtag aaaatgtcgg cgggaaggaa aatatcaatg gtttgacaca
    43321 ttgtatcaca aggcttcgtt tcaaattaaa aaacgaagaa aaagcaaatg atgagatctt
    43381 gaaaaatatg gacggtattg taacggtaat gcgagcggga gggcagtatc aagttgtcat
    43441 tgggaatcat gtgccagtcg tgtttgaaga ggttataaaa gcaggaaacc ttacttttga
    43501 tgaggctgtt tcaacagaaa aaatgagacc gtttgatatg cttattgatg gaatatcggg
    43561 ctgtttccag ccattccttg ctatcctagc tgctggcggg atgattcgtg gactgacagc
    43621 attccttgtc ttcttaggcg cgtttgaccg cggttctggc acatttgtta tgtttgataa
    43681 tatcggtgat tctgtattcc aatttatgcc tgttattatc ggtttaacag ctgcccgtaa
    43741 atttaaagta aatgaattcg tagggatgtt gcttggcgca gcattaatga atcctagctt
    43801 gtcgctggaa gctttgagtg gtgcagcaga agcaccacta acgaccatat tttctggcac
    43861 tatttttgaa gcacctattt atcaaacagt attcggcatt ccctggattg cgcgtaacta
    43921 cgcttcttct gtcattccca ttatctttat tgtgttgtta gctagccaaa ttcagaaacc
    43981 aattaaaaag ttagtacctg agatgatcgc gaatttcttc gttccattct tcaccgttct
    44041 tattacaatg cctttaggtt ttttactcgt tggaccagta ttcacattcg caactgatat
    44101 tttaatggct ggatttgaaa cacttttagc actttcgcca gttatttatg gagcaatcgt
    44161 aggcttcttc tggcaaattc tggtgatgtt tggtctccat tgggcaatcg taccaatggg
    44221 attgatgcaa ttttctgtga atggttggca aaatattatg acacctgttg cagtagtgtc
    44281 ttttggacaa actgcagcac ttaccgcact ctactttaag cttagaaatc caaaagacaa
    44341 agcaattgca ataccagcca ttgtttctgg tattgtgggg attacagagc cagctattta
    44401 tgggtttaca ttaccacgta aaaaaatatt tatttttacc tgtgtcggtg gtgcgttagg
    44461 gggcgcgtat agtgggttaa tgaatttaac ttcttggaat caaggtggac taggcatctt
    44521 tacaattccc aactatatta gaccagatgg tgatttaaca gatgtgatta atgtattgat
    44581 tgggatcgcc attgcgatgg tggtatcctt tacgctgact tttttctttt ggaaggatga
    44641 agcaggtgaa acagatgata tacagaaaaa atcaggtaaa gaaattgtaa aaacaccgat
    44701 acaaggacaa atcgctccac taaatgcagc aaaggatgca gcttttgcac aaggaacact
    44761 aggtcgagga atcttgatct accctgaaaa aggagaagta cgtgcccctt ttgacggaac
    44821 agtcatgacc ctgttcccga cgaaacaggc aattggaatg gtttctgaaa cagggctgga
    44881 attgctgatt catgtcggat tggatactgt gcagttggaa gggaaatatt ttgaaagctt
    44941 agtgcagcaa ggataaagag tgaaacaagg cgatctgttg ctacgcttcg acaaaaagaa
    45001 aatcgaaaag gaaggataca gtttagaaac acctgtgatc gtcaccaatt acacggatta
    45061 tttggatatt ttggaaaacc aaggggagac ggtcgggcca gacgatgcac ttatcaccgc
    45121 actgacctga acggttaggt gaagaatgga ctaggcttaa ctattctttt tattccactt
    45181 ctttattttc aaaattgaaa ggctctttca tgatggctga gctgataggg cgtttatcga
    45241 atttttgacc gacagaaatt agatggacta aattctgttg ataattttct gcaaaaacac
    45301 aactatataa cacgtctaga agataacaaa ttgatgtatt gatcgtaaaa ttaccaattt
    45361 ttgaatacag tcgctcgcgt gtcgtaagtc gcaaagcggc tgtactcatt gcagatagcg
    45421 ttgaatcacc gatactggtc aaagctaaaa ttggaacatg attttgtttc aatatttctg
    45481 cggtacgaag gatcacattg ttttcacccg tataagaaat cagaatcccg cacatatcac
    45541 tcgtgcaatt gtacgcttca tagaatgatt caccaaaagt ggtgacaatc gtgacatcca
    45601 ttttgatgcg cttcattttc agcatgaaat cttgagaaat caaagtattc gagttactgg
    45661 cgaaaatcac gatttttttt gcttgaagca ttagttgttt ggctttttgc agttggtcat
    45721 gatgaatgag agaaagtgta tcatgaatcg tcatctgttc taaagaagcc attttatttg
    45781 cgatcgtcat aataccgtct gtggtggaaa aaggaagatt cgcatctacg tcttgaaaat
    45841 tcccttcaag ataggctgtt tcagctaaaa aagcattacg aaaactgacc cagccatcaa
    45901 aacccatttt ttttgctaca cggatgagtg tagaggggtg gacataacat cgctcagcaa
    45961 tcgcttggat ggtcatttcg ccaagtgctg gagaatcgct taagagaaac tggatcactt
    46021 cattttctga aggagaaaag gagatttctt tgattttttc acgtaataac atgtagatac
    46081 cttcttctta tttttttacg taaattataa cttttttgaa aatgatttgt aaacggattt
    46141 atactatata acttaaaata gacatttttt gacaagatat ttacaaaaat ccactagaaa
    46201 acagtaaatt ttgtaaatgt tactggaaag aaacagattt ctattgtttg ttttgtttac
    46261 aaaaaagata atgaaagtgt aaaaaagtaa aggagtgaga acatggcaaa aggaatcaaa
    46321 atcgctacga ttggtggagg cagcagttac acccccgagt tgatggaagg atttatcaaa
    46381 agatatgagg aattaccgat acgagaaatc tggctcgtag atgtagaaga aggaaaagaa
    46441 aagcttgaga tcgttagtca gatgtctcag cgtatgtggg atgcttctcc gtatgaagtc
    46501 aagatctatg caactctgga tcgggaagaa gcattgaaag atgcggattt tgttacgact
    46561 cagtttcgtg tcggtcaatt agatgcacga atcaaagacg agcggatccc tagttattat
    46621 gggatgattg ggcaagaaac aaatggtgct ggcgggatat tcaaagcttt tcgtaccgtt
    46681 ccagtcgttt tggcaatcgt tgaggacatg aagcgtttat gtccaaatgc ttggctgatc
    46741 aatttcgcga acccaagtgg gatggtgaca gaagcagtta tcagatatgg caaatgggat
    46801 aaagtgattg gattatgcaa tgtgccagtg atggcgatga tgacagaacc agcaatgctt
    46861 ggcaagaaaa aagaagagct gatctacaag tttgccggtc taaatcattt ccattggcac
    46921 aaagtagcag ataataaagg aaatgaccgc acggcagaat tgattgatcg tttatacgat
    46981 gaagagaatg gattaccgaa aaatatcttt gatatcccgt ttttcaaaga acaattaaaa
    47041 caaatgaaca tgatcccttg tggctaccac cgctattact atcgtgaaga agaaatgctg
    47101 gaacatgctt tagaagaata tcaaacgatt ggtacaagag cgcagcaagt gaaagaaaca
    47161 gaagcagagc tatttgaatt atacaaagat ccagaattag accataaacc tgaacaattg
    47221 caaaaacgag gtggcgctta ttattcagac gctgcctgtg aaacgattgc ttcaatctat
    47281 ggaaataaag aaacacagat cgtggtatct acaaagaatg atggagctgt tcctgacctg
    47341 ccggcagatt gtgtagtaga agtcactgcc tatgttggcg cacaaggagc gagaaatgta
    47401 gcgtttggtt ctcttcctgc tgctgaaaga ggctggttgc aagtaatgaa gaatatggaa
    47461 ttgctgacga tcgaagcagc tgtgactggt gattatggga cagctttaca ggcgtttacg
    47521 atcaatccac ttatacgatc aggaaagaca gcaaaacgga tcatggatga gttgtttatt
    47581 gcacaccagc agtatttacc gcaattcaag gagacaatca gccgattaaa agaagaagga
    47641 atcgaagttc aagatgaact ggcaagagaa ttatcaggta atacacatat aatggaggaa
    47701 gtataatggg attcagaaaa gattttttat ggggcggtgc tacagcagcc aatcaatgtg
    47761 agggcggtta tgatgaaggt ggacgcggac tagcaaacgt agatgttgtg ccaatcggaa
    47821 aagaccgttt tcctgttatc accggaaaga aaaaaatgtt tgaatttgat gaggatcatt
    47881 tttatccagc aaaaattgca atcgatatgt atcatcgtta taaagaagat attgctttgt
    47941 ttgcagaaat ggggttcaag acttatcgaa tgtccatcgc ctggagtcgt atttttccaa
    48001 tgggggatga gaaagagccg aatgaagctg gcttgaaatt ttatgaggat gcctttaaag
    48061 aatgccaaaa gcacggaatt gagccacttg tgacgattac gcattttgat tgtccaatgc
    48121 atttgatcaa agaatatggt gcgtggcgtt ccagagaact cgttggtttt tatgaaaatc
    48181 tgtgtcgagt catcttcaat cgctataaag gacttgtcaa atattggctg acattcaatg
    48241 agatcaatat gatccttcat gcaccattca tgggcgcagg gctgtatttt gaaaaaggag
    48301 aaaatgaaga acaaatcaaa tatcaagcgg cacatcatga gttggttgca agtgccatcg
    48361 caacgaagat tgctcatgaa gtagatccgg agaacaaagt aggctgtatg ctggcagcag
    48421 gagcatatta tccatacact tgcaatcctg aagatgtttg ggcttctaga aaatcagatc
    48481 gagaaaatta tttcttcatt gatgtccagt cacgaggaga atatcccgct tatgcattga
    48541 aagaaatgga gcgaaatggc attcagatcg aaatggaacc aggggatgcc gcattgctga
    48601 aagaacatac tgttgatttt atctcttttt cttattatgc ttcccgagtt tcgactaccg
    48661 acaacgaact cttggaacag actgcaggaa atatctttgc ttctgtcaaa aatccatatc
    48721 tgcaagcaag tgaatggggg tggcaaattg atccattagg cttgagaata acgatgaatg
    48781 atatttatga tcgttatcaa aaaccattgt ttattgtaga aaacggctta ggtgcagtcg
    48841 atacgccaga tgaaaatggt tatgtggaag atgattaccg aatcgattac ctggcagcgc
    48901 atatccaggc gatgaaggat gcagtagaac tagacggagt cgatctatta ggctatacga
    48961 cttggggatg tattgattta gtatcagctg gtaccggtga gatgaagaaa aggtacggat
    49021 tcatttatgt cgatcgtgat aaccaaggaa atggcacatt agcccgttca aagaaaaaat
    49081 cattcaactg gtataaaaaa gtaattgatt caaatggaga aaatctttcg aacgattgat
    49141 caatgattta taaaagtcta ttgtttttca gcggattttt cgagtataat aaagctattc
    49201 gagaaacgca agcagaacaa tagacttttt ttcgcattgg ctgtaaagta tgcttacttg
    49261 attaagtaaa ggagaatcta catatgtatg atgtaatcgt tattggcgca ggtcctgctg
    49321 ggatgactgc tgctttatat gcttcacgtt caaacttatc cgtattgatg atcgaacaag
    49381 gtgcccctgg cggccaaatg aacaatacgg cagaaatcga aaattatcct ggattcgatt
    49441 cgatcatggg ccccgatcta gcttataaga tgtatgaaag tgtctcaaga tttgggacag
    49501 aaaatgctta tggaatcgtt caagatatca aggatcacgg cagccataaa gaagtcatct
    49561 gtgaagataa aagttacgaa ggaaaaacag tcattatcgc aacaggatgt atccaccgta
    49621 aattaggcgt acctggcgag gaagaatttg ctggacgagg cgtttcttac tgtgcagtct
    49681 gtgatggtgc gtttttccgt aacaaacgtc tagtagtcat cgggggtggg gactcagcag
    49741 tagaagaagc catctatttg acacaatttg cttctgaagt agtgatcgtc caccgtagag
    49801 atgaattacg tgcacaaaag atcatccaag accgtgcatt tgcaaatgaa aaaatttcct
    49861 ttatgtggga tacagtcgtt gacgaaatcg ttggaaacga aatggtagtg acaggtgtga
    49921 aagcacgtaa tgtcaaaacc ggcaatgaat ttgatttagc agcagacgga gtattcatct
    49981 atgttggact ggatccatta actgcacctt ttagagaagc aggtttgacg aacgaagctg
    50041 gctggattcc aacagacaac gaaatgaaaa cgaatatgcc aggcgttttt gccatcggag
    50101 atgttcgtga aaaagatttg cgacaaatca ctacagctgt tggtgacggc ggtattgctg
    50161 gacaacaagt gtataaatac ttggagtctt tagaagaaac aacagcataa gtttaaaaag
    50221 agtagaagaa cgggttcaat tgttctttta ctcttttttt tcgcgtgaaa tttactgaat
    50281 ctgatttatg cgaacacgtc caacaccttt tgataaaaga atcctttctt gatttaagcg
    50341 ttttttggtc ctcatacttt catatctaat aagtgaatgc tatacttatt aagaaccata
    50401 tttcagaaag aggtgttatt ttcatgtctt gggaacaagt gtatgaacaa tgggtacatg
    50461 aagaaaattt agaagaaaac ttaaaaaaac aattaaatga tctgggtgaa gatcctgaaa
    50521 aacttgaaga tgctttttat gcaccgttgg aattcggtac tgcaggtatg cggggaatct
    50581 taggacctgg gatcaatcga atgaacatct atacggtaag acaagcaaca gaaggactag
    50641 cacgtttcat ggatacacaa ggtgaagaaa caaaacgccg aggtgtcgct atcgcttatg
    50701 actcacgcca tcagtcacca gaatttgcaa tggaagcagc caaaacacta gcacatcaca
    50761 atatcccgtc ttatgtattc gaaagtctgc gtccaacacc agagctttct tttgcagttc
    50821 gtcatttgaa gacgtttgcg ggaatcatgg taaccgcatc tcacaaccca gcggcttaca
    50881 atggatataa agtctacgga gaagatggcg gacaaatgcc tcctgcagac gcagatgcat
    50941 tgacgaaata tgtccgtgaa gtcagcaatc cgctaaaagt cgaagtatta tctgacgaag
    51001 aagctaaaca tagcgggttg atcacgatca tcggagaaga agtggacgct gcttatctag
    51061 aagaaatcaa agcagtgacg attgatcgtg aattggttga aacaatgggg aaagatttga
    51121 aacttgtgta cacgccactt catggaacag ggaaaatgtt gggcgaacgt gcgttgaaac
    51181 aagctggatt cgaacaattc gtactagttc ccgaacaagc tgtggcagat ccagatttca
    51241 ctacggtcaa atcgccaaat ccagaagaac attcagcttt tgaatatgct atacgacttg
    51301 gagaaaaaga aggagctgac ttgctgattg caacagatcc tgatgcagac cgtttaggcg
    51361 cagcggttcg tttgccagat ggttcttatg aagtattgac tgggaaccaa atcggagcat
    51421 tgtttgctca atatattttg gaagcacatc aatcaagagg cactttacca gaaaacgcag
    51481 cggtattgaa atcaatcgtt tccagcgaat tgcctacagc aattgcggaa cactacggtg
    51541 ctaccatgtt caatgtgttg acagggttta aattcattgc tgaaaaaatc caacaatttg
    51601 aagaagacca ttcacatact tttatgtttg gattcgaaga aagttatggt tatttagtta
    51661 aaccttttgt tcgcgataaa gacgcgatcc aagcattgct tttattagca gaagtagcag
    51721 cttactataa aaaacaaggc aaaacgttgt atgacggctt gcaaacgatt tttgaaacct
    51781 atggctattt cgcagaaaaa acgatttctg tgacaatgag cggacaagaa ggttctgcga
    51841 aaatctctgc tttgatggaa aaattccgta aagaagcacc gacagaattt gccggagcaa
    51901 aagttattca aacagaagac tttaaagaat tgacgagaac agaccgtgaa ggaaacgtag
    51961 aaaaactaac aacaccgcca tccgacgtat tgaagtatac attggaagaa aatggctgga
    52021 ttgctatccg cccttcagga actgagccga aaatcaagtt ttatattggt gtaaaaggaa
    52081 gttctacaga agacgcagcc gaaaaagtag cctcttatga agcgattatc aaaaagatga
    52141 cagaagaata aaaaacttga gactgatgga aaaagtggta aactttagaa gtcagtcttt
    52201 tttcaagttg gaggtgaatg gattgccaga cacgcaaaaa tcaaaagtag agaaagtcag
    52261 tcaattattc aaaatgttga gtgatcccac tcgtcttaaa attctgctat atctgaaaga
    52321 cggggaacaa aatgtgacag caatcaccca agcagtggaa atggagcagt ctgctgtatc
    52381 gcatcaacta cgtttattaa gagaaaatca tgtcgtcaag tctcatcgcg agggaaaagc
    52441 gattttgtat agtcttgatg attctcatgt actggatatt ttgaaccaga cactcaaaca
    52501 tgtggaacat caataacgat aggtgcaaat agataaacac tggagtgtga caacgaagaa
    52561 atttcgttgt cacactccag tgttttttaa gaaaaagaca aaaatgatca atcgcttttt
    52621 tctgttgttt cagttccata ataactatga tcttctaggt ctaaagcatt caaaataagc
    52681 gaagccgttt cttcaataga taaagatgct acattgatca ctacacatcc tagtttttca
    52741 taaagatcat tcgcaaaatc gagttcagct ctaatttttt cgatatcgga ataagcagta
    52801 tcagggttta atccgtaaga gcgcatccgt tctttacgga tattatttaa aatatctggg
    52861 ttatttgtta gtcccacgat ttttttagga tcgatctccc aaagctgttt gggaatatgt
    52921 gcttgtggga tcaaaggtaa attggcaact tttaaatttt tgttagctaa aaacaagctc
    52981 aaaggcgttt tggaagttcg ggatacgcct agcaaaacga catctgcttc taaaaaacca
    53041 cgaggatctt tcccatcatc gtattttaca gcaaattcca ttgctttgat ccgtttgaaa
    53101 tagttctcat tcaataaatg gagggcacca ggttgccgaa ttggcttgat accagttaaa
    53161 cgttcaattt ctgatatcgg tggcgtcatc acatcaaaac taaataattg atgttcttca
    53221 caaaaagaac gtgttatctc gatcagttct tgattgatta atgtatgcag gacaagtgct
    53281 ttttcttcta atgcatcttg caatgcctgc cttaatgttt tttcatctgt cacgaacgtt
    53341 ctgcggaata ggttgaactc aacggtagga tactgagcca tagtagcttg cgctagtttt
    53401 gtcgcagttt ctccagcaga gtcggagatg acaaaaaaag taacgatttc tgtagaatcg
    53461 gaagtcatgg ataaaacctc acttgcattt tttttatgtt tattatacca tactctagaa
    53521 tgcgtacttc gtaatcattt tgatttggag ggataagtca tgaaaaaaca gacattgatc
    53581 gaacaatcat tagaaacatt gaaaaataac ggttttaaat atactaaaaa aagagaagca
    53641 ttgttaactt atttagtgaa gcgtaaccgc tacgtatctg ctaaagaagt ttttgactat
    53701 atgaatcagg aattcaaagg ggtaagttat gatacgattt accggaatct ccatgatttt
    53761 gcagagatcg atttactgga agaaaccgat ttaaatggag aaatgaagtt tcgttttcat
    53821 tgctgtcagg ggaaaatcgg ccatcaccat cattttatct gtacagtgtg cggaacaacg
    53881 aaagaaatcc atatgtgtcc gatgaattat ttcgaagaac agctaggtgg atgcacgatc
    53941 gaagggcata gattcgagat tttcggaaga tgtgaaaatt gtcaataagg atttaaataa
    54001 aataacattt gataatttta aaaaaaagca agatttcctt gacggtcaaa acagcattag
    54061 atataatatt tacaggacag tcttgttttt tgagatatat ttcaataaca attacggtta
    54121 ctttttaagc tcggagggag ggaattaaca tgtcaaaaac agtcgttcgc aaaaacgaat
    54181 cacttgacga tgctcttcgt cgcttcaaac gttccgtgtc aaaagcgggt actttacaag
    54241 aatctcgtaa acgtgaattc tacgaaaaac caagtgtaag acgcaagaaa aaatctgaag
    54301 cagctagaaa acgcaaaaaa ttctagttct gtgatgaatt ggagttggta gtgtgtcact
    54361 actaagtaga ttaaacgatg acatgaaagc agcgatgaaa gcgaaagata aggaatcttt
    54421 acaagtcatc cgaatgatca agtcatctat acaaaacgag cagattaaag aaggtcacga
    54481 cttgacagaa gaagaagaac taacggtgtt gtctcgtgaa atgaaacagc gacgtgattc
    54541 tttgcatgag tttgaagaag caggacgtga cgatttagct gaaaaagtaa aaagtgaaat
    54601 tgtaatagtc gaaaaatata tgccggaaca actttccgac gaagaaattc gacaacttgt
    54661 tcaagaagca atcactcaaa ctggtgcttc atcaatgaaa gaatttggca aagttatggg
    54721 tgcaattatg cctaaagtca aaggaaaagc agatggaaac caagtgaatg cgattgtgaa
    54781 agaactatta caatcttaat tttatcattt aaactgcgga cagtgattat ccgcagtttt
    54841 ttgtgttcgt aaaaaaagaa ctaaaaaaca gctagaagaa agaatcttat tctt
//
LOCUS       DADQCX010000008        52449 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.008, whole genome shotgun sequence.
ACCESSION   DADQCX010000008 DADQCX010000000
VERSION     DADQCX010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.008"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..794
                     /locus_tag="J8R83_000420"
                     /pseudo
     CDS             1..794
                     /locus_tag="J8R83_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            934..1860
                     /gene="cysK"
                     /locus_tag="J8R83_000421"
     CDS             934..1860
                     /gene="cysK"
                     /locus_tag="J8R83_000421"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAZ9573581.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2096..2542
                     /locus_tag="J8R83_000422"
     CDS             2096..2542
                     /locus_tag="J8R83_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAZ9573582.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2814..4166
                     /locus_tag="J8R83_000423"
     CDS             2814..4166
                     /locus_tag="J8R83_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9573583.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4337..4624
                     /locus_tag="J8R83_000424"
     CDS             4337..4624
                     /locus_tag="J8R83_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573584.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4850..5293
                     /locus_tag="J8R83_000425"
     CDS             4850..5293
                     /locus_tag="J8R83_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9573585.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5299..6483)
                     /locus_tag="J8R83_000426"
     CDS             complement(5299..6483)
                     /locus_tag="J8R83_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAZ9573586.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6751..7449
                     /locus_tag="J8R83_000427"
     CDS             6751..7449
                     /locus_tag="J8R83_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAZ9573587.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7456..8133
                     /gene="nth"
                     /locus_tag="J8R83_000428"
     CDS             7456..8133
                     /gene="nth"
                     /locus_tag="J8R83_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAZ9573588.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8259..8792)
                     /locus_tag="J8R83_000429"
     CDS             complement(8259..8792)
                     /locus_tag="J8R83_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573589.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9089..11470)
                     /locus_tag="J8R83_000430"
     CDS             complement(9089..11470)
                     /locus_tag="J8R83_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAZ9573590.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11460..12107)
                     /gene="recU"
                     /locus_tag="J8R83_000431"
     CDS             complement(11460..12107)
                     /gene="recU"
                     /locus_tag="J8R83_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAZ9573591.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12171..12710
                     /locus_tag="J8R83_000432"
     CDS             12171..12710
                     /locus_tag="J8R83_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAZ9573592.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12800..13219
                     /gene="gpsB"
                     /locus_tag="J8R83_000433"
     CDS             12800..13219
                     /gene="gpsB"
                     /locus_tag="J8R83_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAZ9573593.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13241..13608
                     /gene="rnpB"
                     /locus_tag="J8R83_000434"
     ncRNA           13241..13608
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="J8R83_000434"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13817..14983
                     /locus_tag="J8R83_000435"
     CDS             13817..14983
                     /locus_tag="J8R83_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAZ9573594.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15029..16525
                     /locus_tag="J8R83_000436"
     CDS             15029..16525
                     /locus_tag="J8R83_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAZ9573595.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16606..17289
                     /locus_tag="J8R83_000437"
     CDS             16606..17289
                     /locus_tag="J8R83_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9573596.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17934..19124
                     /locus_tag="J8R83_000438"
     CDS             17934..19124
                     /locus_tag="J8R83_000438"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAZ9573597.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19226..20179
                     /locus_tag="J8R83_000439"
     CDS             19226..20179
                     /locus_tag="J8R83_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAZ9573598.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20248..21597
                     /locus_tag="J8R83_000440"
     CDS             20248..21597
                     /locus_tag="J8R83_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9573599.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21780..22103)
                     /locus_tag="J8R83_000441"
     CDS             complement(21780..22103)
                     /locus_tag="J8R83_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573600.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22232..23395
                     /locus_tag="J8R83_000442"
     CDS             22232..23395
                     /locus_tag="J8R83_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573601.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23465..24814
                     /locus_tag="J8R83_000443"
     CDS             23465..24814
                     /locus_tag="J8R83_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAZ9573602.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24859..25290)
                     /locus_tag="J8R83_000444"
     CDS             complement(24859..25290)
                     /locus_tag="J8R83_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9573603.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25678..28320
                     /gene="alaS"
                     /locus_tag="J8R83_000445"
     CDS             25678..28320
                     /gene="alaS"
                     /locus_tag="J8R83_000445"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAZ9573604.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28520..29116
                     /locus_tag="J8R83_000446"
     CDS             28520..29116
                     /locus_tag="J8R83_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9573605.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29238..30386
                     /locus_tag="J8R83_000447"
     CDS             29238..30386
                     /locus_tag="J8R83_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAZ9573606.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30424..30837)
                     /locus_tag="J8R83_000448"
     CDS             complement(30424..30837)
                     /locus_tag="J8R83_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAZ9573607.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30916..31347
                     /locus_tag="J8R83_000449"
     CDS             30916..31347
                     /locus_tag="J8R83_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAZ9573608.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31446..31679)
                     /locus_tag="J8R83_000450"
     CDS             complement(31446..31679)
                     /locus_tag="J8R83_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAZ9573609.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31862..33532
                     /locus_tag="J8R83_000451"
     CDS             31862..33532
                     /locus_tag="J8R83_000451"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAZ9573610.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33679..34065
                     /locus_tag="J8R83_000452"
     CDS             33679..34065
                     /locus_tag="J8R83_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573611.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34052..34750
                     /locus_tag="J8R83_000453"
     CDS             34052..34750
                     /locus_tag="J8R83_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9573612.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34755..35219
                     /locus_tag="J8R83_000454"
     CDS             34755..35219
                     /locus_tag="J8R83_000454"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAZ9573613.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35216..36127
                     /locus_tag="J8R83_000455"
     CDS             35216..36127
                     /locus_tag="J8R83_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAZ9573614.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36362..36901
                     /gene="pyrR"
                     /locus_tag="J8R83_000456"
     CDS             36362..36901
                     /gene="pyrR"
                     /locus_tag="J8R83_000456"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAZ9573615.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36915..38198
                     /locus_tag="J8R83_000457"
     CDS             36915..38198
                     /locus_tag="J8R83_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAZ9573616.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38211..39137
                     /locus_tag="J8R83_000458"
     CDS             38211..39137
                     /locus_tag="J8R83_000458"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAZ9573617.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39156..40436
                     /locus_tag="J8R83_000459"
     CDS             39156..40436
                     /locus_tag="J8R83_000459"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAZ9573618.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40441..41517
                     /gene="carA"
                     /locus_tag="J8R83_000460"
     CDS             40441..41517
                     /gene="carA"
                     /locus_tag="J8R83_000460"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAZ9573619.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41522..44707
                     /gene="carB"
                     /locus_tag="J8R83_000461"
     CDS             41522..44707
                     /gene="carB"
                     /locus_tag="J8R83_000461"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAZ9573620.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44761..45537
                     /locus_tag="J8R83_000462"
     CDS             44761..45537
                     /locus_tag="J8R83_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAZ9573621.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45534..46466
                     /locus_tag="J8R83_000463"
     CDS             45534..46466
                     /locus_tag="J8R83_000463"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAZ9573622.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46463..47179
                     /gene="pyrF"
                     /locus_tag="J8R83_000464"
     CDS             46463..47179
                     /gene="pyrF"
                     /locus_tag="J8R83_000464"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAZ9573623.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47186..47815
                     /locus_tag="J8R83_000465"
     CDS             47186..47815
                     /locus_tag="J8R83_000465"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAZ9573624.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47803..48117
                     /locus_tag="J8R83_000466"
     CDS             47803..48117
                     /locus_tag="J8R83_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573625.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48155..48796
                     /locus_tag="J8R83_000467"
     CDS             48155..48796
                     /locus_tag="J8R83_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9573626.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48827..49531
                     /locus_tag="J8R83_000468"
     CDS             48827..49531
                     /locus_tag="J8R83_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAZ9573627.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            49528..50430
                     /locus_tag="J8R83_000469"
     CDS             49528..50430
                     /locus_tag="J8R83_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9573628.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50588..52294)
                     /locus_tag="J8R83_000470"
     CDS             complement(50588..52294)
                     /locus_tag="J8R83_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAZ9573629.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17146 a         9140 c        11269 g        14894 t
ORIGIN      
        1 ggaacgagtc ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca
       61 gatgaacaag gatctcaaac agttgctgat cctcaagcgt ttatcgatca aatcggctgg
      121 tctgcgtcag aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg
      181 ttgttggaaa gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc
      241 ggtgtgaaag gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaacg
      301 gacaatgggt aacgatgaat gaaccattcc gaaaatattc ttcttattgg gaatccttcc
      361 aagaccatgc gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg
      421 gcgtgtggaa aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt
      481 atgctaccga tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa
      541 cccgttttga tacgccatca acaggttcgg ctaccacaag tacaacaaca acgactacta
      601 cgacgacttc aacgtcatca tcttcaacaa cagatgtaaa tacaaataat ggtcagacat
      661 atacagtcgt gtcaggtgat acgctatggg atattgcaca aaaatttggc atgtctgttg
      721 atgatctaat ggcgaaaaat ggcatgtcta tgtccagtta ttctttatta gttggtcaag
      781 aactaaacgt ttgatttaga taaaaaggca aagaaactac catatatggt atatctttgt
      841 cttttttttg ctagtcaaag acgaatcact cgccataaat gaacagattg tattatgata
      901 agtaagaaga gcaaagacaa ggaggaattg aagatgacag ctatctataa ctcagtcacc
      961 gaattgattg gcaaaacgcc aatcgtcaaa ttaaataaaa tcgtaccaga agattcagca
     1021 gatgtttttg taaagcttga gttttttaat ccaggaggaa gtgtaaaaga tcgtattgct
     1081 ttaagtatga tagaaaaagc agaacacgat ggtctactga aaccaggtga tactatcatt
     1141 gaacctactt ctggaaatac aggaatcgga ttgtcgatgg taggagttgc aaaaggatat
     1201 aaagtaatca tcgtgatgcc tgagacgatg agtatcgaaa gacgtttatt gatgaaaggg
     1261 tacggcgcag agttgatttt gactcctggt gcggatggta tttctggatc aatcagagaa
     1321 gcagaacgtt tggcaaaaga aaacggctac tttttaccat tacaatttga aaatgaagca
     1381 aatcctcttg tgcatgagaa gacgactggt cctgagatac atcaagcatt tggagtaaat
     1441 ggcttggacg cgtttgttgc aggtatcggt acaggaggaa cgatcactgg cgctggccga
     1501 gaattaaaac gtgtgtatcc gaaaatcgaa ttaatcgggg tagaaccagc agaatctgct
     1561 attttagaag ggaaagaagc gggacctcac aaaatccaag gaatcggtac aggttttgtt
     1621 cctaaaacac tggatacttc tgtgtatgat aaagtccttt ctattagtgg agacgaagcg
     1681 atggaaacag ctagagaagt tgggcgaaaa gaagggattt tagtaggcat ctcatctggc
     1741 gctgcaattg ctgccgcgct aaaagtcgca aaagaattag gaaaaggcaa gaaggtatta
     1801 gctgtggttc ccgacaatgg tgaacgttat ttatctacag ccctttacca agagatataa
     1861 ggcacttggt ttttctccag ataggtttat gtaaaaaact tttaaagatg aaaagaacac
     1921 acaaaaattt atgatgagaa aaattatttg aatagagacg taaaatagtg aacgcgactg
     1981 ttttacgtct tttttcatta aaatacaata aaattgaatt ttcttttcat gttaagtgga
     2041 ttttaaaatg taaaaatagt atgataagac gagaataaca acgtggggtg tttacatgga
     2101 aaataagtta gtcgaagagg ttatcgaaaa gttaaaaaaa gagaacattc gaatcacacc
     2161 tcaacggtac gcggttttag aatatttgat tgaacatcat tcccatccaa cggctgatga
     2221 gatttataaa gcacttgaac atcggtttcc aaatatgagt gttgcgactg tttacaataa
     2281 ccttcgctta tttacttcga ttggatttgt tcaagaaatg aagtacggcg atgcttctag
     2341 ccgatttgat ttcagttcaa agcgtcatta tcatgtaatt tgtgaaaact gcggtaagat
     2401 tgttgatttt cattacccag ggcttgaaga tatagaaatg gctgcgagca gactgactga
     2461 ttttgagatt aatgaacatc ggttggaatt gtatggactc tgtccggatt gtaaagagtc
     2521 agcaaaaaag gcgcaaatgt aaaaacagtt tctataagtg ttatacctaa aaaaagctag
     2581 ctgtgtaaaa aaacgctagc ttttttattt ttttgtcttt tattcacaat cttagatatc
     2641 aaagtgaata ttatcacaat aagaatcttg tagatattgg gttcttatgc ttgaaaagga
     2701 atgaaactac aaacaaacct ttgtgaattc acaagcatta aactgttgta tccgttttat
     2761 ttctgttata gtagttttgt cgaaggacaa aatgttaatc ggagggacca taaatgaaag
     2821 tagtagtaat tggctgtact catgcaggta ctgcagctgt aaaaagtatt ttaaaaaatc
     2881 atccagaagc agaagtgaca gtatatgaaa gaaatgacaa tatttctttc ttatcttgcg
     2941 gtatcgcact ttatgtcggc ggagtagtaa aggacccagc aggcttgttc tactcaaatc
     3001 ctgaagaatt atcttcatta ggagcaacag ttaaaatgga acacgatgta acagacgtcg
     3061 atacagaaaa taaaacagta acggcaaaag atctgaaaac aggagaaaca gaaacggttt
     3121 cttatgataa attagtgatg acaactggtt catggcctat tatcccaccg attagtggaa
     3181 tcgatgcgaa aaatgtactc ctatgcaaaa actacaatca agcaaatgaa attattgcac
     3241 aagcgaaaga agcaaaacgt gtagtaattg ttggtggtgg atatatcggt attgaattag
     3301 tagaagcttt tgtcgaatct ggaaaacaag tgacattgat tgatggatta gatcgcatct
     3361 tgaataaata tctagataaa ccattcacag atatcttaga aaaagaattg acagaccgcg
     3421 gtgttactct tgcgctaggc gaaaatgtta ctgaatttat cacagatgaa gaaggaaaag
     3481 tgaaacaagt agctacacca acagatacat ttgatacaga tatggtcatt ttatgtgtgg
     3541 gcttccgtcc aaatacaaaa ctgatcgaag gaaaagtaga tacactgcca aacggggcaa
     3601 tcaaagtgaa tgaatacatg cagacaagtg atccagacat ttttgcagct ggagactctg
     3661 cagtagtcaa ctacaatcca agtggcacgc aaaactatat tcctttggca acaaatgccg
     3721 ttcgtcaagg tttacttgtg ggaaataact tgacagatca taaaatggcg tatcgtggta
     3781 ctcaaggaac ttcaggactt tacctatttg gctggacgat cggttcgaca ggtgtgacca
     3841 aagaaagcgc aactttgaac gatctagaag tccaagcgac tgtatttgaa gataattatc
     3901 gtccagagtt catgccaact actgaaaaag taatgatgga gctagtctat gaaaaaggaa
     3961 cgaatcgtat cgtaggtgct cagttcatgt ccaaatacga cattacacaa tcagcaaata
     4021 ccatgtcttt agctgttcaa aataaaatga ctgtagaaga tctcgcactt tcagatttct
     4081 tcttccaacc acattttgac cgcccatgga attacttgaa cctacttgca caagaagcgc
     4141 taggcgaaat cgaaactgca caataaagaa aaagggttgt gacacaattt tgtcacgacc
     4201 ctctgtcttt ttttgtgaaa agtacaatta gttgtctttc ttcgaatttt ttgtcacaat
     4261 aagcagcaaa gataaagctg ttacataaaa gaacaagcag ctttatttga ttttgaaaag
     4321 aaaggtgaga aagaagatga ataaagaata ttttgtccaa caagatgcat ttttagaaga
     4381 ttataaaagt gcttcgaaga aattaacgat caatattgat gagttggcag atcaagtact
     4441 ctctcagttg aatgaaacgc aagaggaata ttacacgatg ccagcaaatg acgccaaaga
     4501 taatgtttct catcgttttc ctttcagtag acgcatctac tcagatgaaa atgacggcac
     4561 attgaataca gagtacacat atgaaggtca gccatatgtg ctagaaactg atgatgatct
     4621 ttaaagacag tttttgaaaa ggccgctcat ccttaagtga tgacaaaaaa tcatcacaat
     4681 taccgatgac tgtctcttta ctatctttta atcagaaaaa ggggttatga caagctttgt
     4741 caaccccttt ttttcttggt ttcagattgg gttttcctac aaaatatttt tatctttgtt
     4801 gaataggaaa caaaaaaaca atataatgaa agaaaaagaa ggtgtagaaa tggataaaag
     4861 acaactgcta atagaagaat atctggattt agctaatgag attattcatc gtaataaacc
     4921 agaaatggaa aaagaatttg caggatttac tctaaatgaa ctagaagtga ttgaacatat
     4981 cgggaaaatc cctgatccta acgtgacaaa attagcgaat gctagttaca tgactagagg
     5041 agccatcagt aagctaacaa aaaaactgat agctagaggg atcataaaca cttatcaaag
     5101 cgaagagaat aaaaaagaaa tctattttca attgacgcca atcggacaaa aaataaggaa
     5161 tagacacgag caactccatc aaaaatgggt acagcgagat gctactgtat ttgaaaatat
     5221 gtcaaaagaa gaatttgaca cagtatttcg ttttatcggt cgatacagag aatttatacg
     5281 aagtagcaaa tgaagctact attttttatt gtagtgataa taggcaaaaa tcataagcaa
     5341 aaatccgaat accgtcggaa gaaatggtgc tgcagcataa agctgtcctg cgattagcgg
     5401 gccgatgacg cgcgatagag attgtatact ttgggtaccg cccattacaa gaccttgctg
     5461 gttatctgag acagaattgg atagttggcc attgaataca ggagtaaaaa tagaatcacc
     5521 gaaaccataa cagataatcc caaataaaaa caaaatcggc agtagaagaa ttccagataa
     5581 tgtgatgaat agataggcga ggatttcact gaacatccct attcttgtga tctgctgttc
     5641 tgaaaatttt ttgagcaatc gaggcataat gaacaattgc gagacagtat ccaagattcc
     5701 aatcaaagag aagcttaaac caaccaaccc agccttccac tgaaaggcgt caatcgaaaa
     5761 ttgagaaaag atagattgaa gagagccagc tgccaaccaa acagcaaaac ctgctgtcaa
     5821 taaaggaata acggatgaaa tcttgaataa ttgttgtaat tggtgaaaag gtcttacatg
     5881 ggagaaactt aaatctactg aacgtttttt tattggaagg ctttctagca taaatgtgta
     5941 gccataaacg gcatttaaga aagtaaagag tgctccaata aatataggaa cagaattccc
     6001 caactcagct aatagacccc ctataatagg acccagcgtt gttcctatac cgactaaagc
     6061 acccatccat ccaaaaactt tggttctttc attaggttcc gtgatgtcgg caaagtaagc
     6121 atataaggtg gagatttctc ctgccgtcaa tccttcaatg atacgaccaa ggaacaacat
     6181 ccatatcgaa tttcctaaac caaaaagcaa atatccgata cttgatccta ataaactgat
     6241 aataaggatc ggatgacgcc caaaatgatc acttaagcta ccgagaatgg gggcagataa
     6301 gaaggcagct agagcataaa cagacatgag caaagtgata tagaaagctt gctgatgtat
     6361 ggagtgagaa taaggcagcg ttaaaaacgg aagtacagga ctgacgatag taaatcctaa
     6421 tccagtgaat aagacagaga cgtatccaaa aactttagaa tgtttatttg tgaaactgta
     6481 catgtaaaaa ctcctttatg caataatgtt aacttggaaa caaaaatagt gtatagtaat
     6541 tttgtttcct tgtcaacatt ctaaggaaca gcgaaatcta cttaatttat ttattccgaa
     6601 aagtgaagat acgcatcaaa aacatgaaca aacaaaaatc aagtagacga cattgtaaat
     6661 ctgaccgatc agtgaagtaa atagaaaaga aacctgttct tgcttcccat gtttttttta
     6721 cgtatactgt gattgagcgg aggagaaatc atgttgaatt tagaaaatta cttaagcgct
     6781 ggacaaacag tcatatctaa tcttttactt aaaaattatc ataggatcgg tctacaatct
     6841 gaagaatttt tatttgttct acagttgcat atggcacagc ttgaaggaga tactttccct
     6901 gatttgcaga tgattgctat ggatatggga atcaaacaag atcagatttt tcaaatactg
     6961 gatcgtctcg taacaaatgg atttatcaag atagaaacga cgattgtcaa cggtaaaaaa
     7021 gcagatcgat ataatcttta ccccatctat gatctattag gtgagtattt aaaaacacaa
     7081 gaaaaaaaat acgaagaaaa aacacaagaa aaagaaatcc agtcagtgta tcaattattt
     7141 gaacaagaat ttggacgccc gctttcttcg atcgagttcc agcggatcgg acaatggcta
     7201 gaagaagacc attatcagcc ggaaattttg aagctagcac tgcgggaagc cgtattaaat
     7261 caggcttata gttttaatta cgttgaccgc attttgctat cgtgggaaag aaaaaatcta
     7321 cgtacaaaac aacaagtgga agaagaccaa aaacgaagaa aacagcagct tcttcaaaga
     7381 gaagtagaac agtcagctca acaagaagaa ttgccgaaag tctcactgaa aaattggttg
     7441 gaggagtagc ggaatatgtt aagcaaacaa aaaacaatgg aagctctaga aacgatgtat
     7501 ggaatgtttc ccgaagcaca tggagaactc aagcacaata atccatttga gttattgatt
     7561 gcagtgatct taagtgccca ggcgacagat gtatcagtga ataaagcaac gccagatttg
     7621 tttgcctctt ttccgacacc cgatgcgtta gcagaagctt caatcgatga aatcattctt
     7681 aaaataaaaa cgattggttt gtatcgaaat aaagcaaaaa acatcaaagc gtgtgcacag
     7741 cagctgattg aacgtttcga tgggcaagtg ccaacgtcaa gagaagaatt gatgtctctt
     7801 cctggtgtag gcagaaagac agcaaatgtc gtattggggg atgcattcgg gataccagca
     7861 atcgcagtag atacccacgt ggaacgtgtc tcaaaacgcc tgaggatctg caaactagat
     7921 gctacggtca tggaagtaga agaaacactg atgcggaaag taccacaaga attatgggta
     7981 aagacacatc atacactgat tttttttggt agatatcatt gcacggcaag aaatcccaag
     8041 tgcgaggtat gtcctttgct atcaatatgt caagatggga aaaatcggat gcgtctaaaa
     8101 gaaaaggcgc taaaaaagaa accacgcctg tagacgtggt ttctttaatt gcaaataaat
     8161 gtatgaatta tcttgttatt atggagaaaa gctgtttcgt ttatcttttt tgcatgaaaa
     8221 agtaaatgta catactcagt agctaggatg gtaacttatt acaatttatt gcgataaaaa
     8281 taaaagttgt tatttttatt gggaaaatac ccgatgtaga aaataatgcc ttccaatata
     8341 cctataaaat aagtccagta ttccaaagga ttatataaat aagtgacgta tctatctaaa
     8401 ggtgtaataa aaatgataag tgataataaa aaaataccat ttataactaa acataaacta
     8461 atggatttgg gcggtttcag gctcatcaga aaaatataga ttctggtgaa caacaaccat
     8521 aaaaaagtga gaatcattgc atgagagctt ctttccataa attttccttt aagagtagtg
     8581 cttaaaagta cagaaaaaat aataaatgca aggataggag caattaaagt aaatttattt
     8641 aataataaac aaaatttttc agctttttta ttcttggaat aacgaggtat tgttttcgat
     8701 aaaaaaagat ggtgcagaca aattatgata attaagcata ctatcagata actcaaaatg
     8761 aagccttctt tcaaaaaatt attcaaaacc atatattgta ttttttattt gataataaca
     8821 atgggattat taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt
     8881 ataaacaagt aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt
     8941 ttaagctaaa tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa
     9001 tacagcttgg tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac
     9061 cacgcttgta gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg
     9121 atggtgtatg gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag
     9181 gaggagcaga tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg
     9241 aagacgctgg ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt
     9301 cgctttgact agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag
     9361 tctggacata gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg
     9421 tatattgatc tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc
     9481 agtctgtatt tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg
     9541 ctacgtgtga cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg
     9601 aaatcgaata atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa
     9661 taccaagttt tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat
     9721 ataacccagc gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt
     9781 ctgtgatcat ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt
     9841 cttctgttcc gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc
     9901 cattggcgaa agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc
     9961 catcttgttc ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga
    10021 tcccaagatt ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga
    10081 ctgctggaac attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt
    10141 gattatccca gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa
    10201 tagtttttcc agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt
    10261 tcatcgtaga accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt
    10321 cttctgcgat gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa
    10381 gggtggaggc aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga
    10441 tatcatatag tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg
    10501 tgtagacatt cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat
    10561 cgacgatctt agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta
    10621 cattaacagc ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca
    10681 aaacagtatc tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag
    10741 gggcttgagg catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct
    10801 taccaaagta catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt
    10861 tatttacgta gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca
    10921 tccacgcttc ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg
    10981 aaagtttgat caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt
    11041 tagagagggc agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc
    11101 gatcttctac cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt
    11161 tttcacgctt ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg
    11221 aagatacggt agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc
    11281 agaaaagtcc tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga
    11341 tcttgataaa taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat
    11401 tcttcttcac actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt
    11461 catttgccat tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg
    11521 tccaaataag gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc
    11581 aaagataaag gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa
    11641 tgaacactat tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag
    11701 accccatttt gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta
    11761 aagggaaaag atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga
    11821 tagacgccat tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca
    11881 gcacttctct taggatagtc tactttcacg atttggatag gggtaggctt tttatggata
    11941 accgccaacc cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc
    12001 atcccccgat tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga
    12061 gaggcattct tataataagg ttggccattt ggatagcgca ataccatctt taatcacact
    12121 cctaggccac attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt
    12181 caaaagtaat ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg
    12241 atcctaaaat ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag
    12301 aagggctgga atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa
    12361 tagtagcgga attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt
    12421 ctgattttgg taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat
    12481 tagcagatta tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga
    12541 atcacactcg ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat
    12601 tccctggaaa aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct
    12661 acgaaattcg gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt
    12721 gtttgattta tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat
    12781 gaaaactaga ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca
    12841 agaattcaaa acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa
    12901 tatcatcaaa gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga
    12961 tcgattgagt gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt
    13021 gcaacaaaca gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt
    13081 gtcaaatctt gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa
    13141 accagcacaa cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga
    13201 aaaaacacgt caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc
    13261 tgacttgatc aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg
    13321 tgcttagcga aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag
    13381 gcttcggcta tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc
    13441 catccggtgg aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt
    13501 tttgtctgga agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct
    13561 ttgttttttc tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat
    13621 cagggaatta ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag
    13681 ctatttttca atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg
    13741 ttattcggaa tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata
    13801 aataaggaga ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag
    13861 cgggctagaa gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga
    13921 gaacggacgt gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt
    13981 acgtacagca gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga
    14041 attgtttgaa aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt
    14101 tcctgtagct ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat
    14161 cacaaaaaaa gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc
    14221 actgacggaa actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat
    14281 ggtaactctg gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg
    14341 tggagcacca ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa
    14401 agaccgtcca ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt
    14461 aataggccat aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg
    14521 gttcagtcaa gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga
    14581 tattgaatta gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc
    14641 caatgcagaa gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga
    14701 cttcaaaacg gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct
    14761 aggagaagaa gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt
    14821 aaaaacatgg agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca
    14881 aaaagcaacc aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta
    14941 ttggggaact cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca
    15001 ttcaattgga tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa
    15061 agaaatcaat cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat
    15121 gcctgaaaaa gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt
    15181 ttcaaaaaaa atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga
    15241 agaattgtcg gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga
    15301 acatcgcgta ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg
    15361 acaatggcaa aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca
    15421 aaatattgaa ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta
    15481 tgatgttttg ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt
    15541 tgatcagctt aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga
    15601 acctgaaaca gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt
    15661 gaaagtaatc gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca
    15721 cccatttatg actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac
    15781 agatttcaaa atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca
    15841 agacatcgat gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca
    15901 tgaatcacaa tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa
    15961 gcaatatcct ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa
    16021 attttatcgt ttattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt
    16081 gacttaccct ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg
    16141 ggtagatgtt gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat
    16201 acgaccaaca aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt
    16261 tggttatttt ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt
    16321 gcagcaagaa atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa
    16381 ctggatgtca gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat
    16441 ggatgcaaca catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta
    16501 ttttaatgta tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa
    16561 tctatagatg ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa
    16621 gtgatcgctg attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat
    16681 cataccaaaa gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac
    16741 cgctttgtga cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa
    16801 aatgagaacg aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag
    16861 gaacagatct cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct
    16921 gaagcggccg aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca
    16981 ttaggagcaa tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt
    17041 tttgatcctg aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg
    17101 acagtgatca atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat
    17161 tacggatatg aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt
    17221 tttctggaat ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac
    17281 aaaaaatgat ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc
    17341 gtaaaagtta cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg
    17401 agtcacaagg aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg
    17461 attcggaatt ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt
    17521 gtcacagtcc ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa
    17581 attaaaaatt gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat
    17641 aaataaatta aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg
    17701 tgttgtattt atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca
    17761 tactatataa gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat
    17821 tctcataatc agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac
    17881 acgatatatg tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt
    17941 ccaaagaact aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat
    18001 acaatacgat cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa
    18061 agatgatcaa tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa
    18121 aagcatgtat tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca
    18181 atggttcgct gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag
    18241 aagcagcaat cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa
    18301 tgacaaaaga agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt
    18361 gccgcttatc cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga
    18421 aaaaagcaaa ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg
    18481 gtgttttctc catggatgga gacattgcac gattgccgga aattattccg attgttgaaa
    18541 aatatggact gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg
    18601 caggaaccgt caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat
    18661 cgaaagctat aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt
    18721 tgaaagctag aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag
    18781 ctgcattggc ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg
    18841 aaaatgctaa ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg
    18901 aaacacctat tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga
    18961 agctgatcga acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga
    19021 caggcaggat cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag
    19081 tagcagttta tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt
    19141 cgtctattta aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta
    19201 gtaaaaaaga tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca
    19261 aattggttca gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc
    19321 gacagatata cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt
    19381 aatggattac gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca
    19441 tttggctgct cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa
    19501 cgtgactggg ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac
    19561 gccaagttca atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac
    19621 tcttcagcgt cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga
    19681 ttattattat gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc
    19741 ttatgcaacc ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc
    19801 aatcaaagaa ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta
    19861 tatgccagat gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt
    19921 tcatcgaaat gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc
    19981 tattcaaaaa atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc
    20041 aatagcagaa tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt
    20101 ttcgccgaaa tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa
    20161 attggtagag acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat
    20221 tggctatggt atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa
    20281 gtaaaaatag aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt
    20341 atgggcacag tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca
    20401 ggatccgcca gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca
    20461 ggactaacag gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat
    20521 atcgaacgga tttacggaaa tacagcagct tttttattgg gctgggcgca agtcgtgatt
    20581 tattttccag caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta
    20641 tttggtcttt cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg
    20701 ttgatcaatt ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc
    20761 aagcttattc ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac
    20821 ttccaactgt ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg
    20881 ggcttgctag caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga
    20941 gaattgaaaa agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc
    21001 atgatcgttt atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc
    21061 gcaggaaaca gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga
    21121 agactggtca cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt
    21181 actggaatgc gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc
    21241 tttgctaaac ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc
    21301 atcgctattg gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt
    21361 gtcatttgga ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa
    21421 cctgatttgt ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc
    21481 attggaggga cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg
    21541 gggatagtat tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta
    21601 aaacattcga attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg
    21661 aggagtacgt ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt
    21721 tgtctacgat gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt
    21781 tactttgatt tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc
    21841 aagcaaccag aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta
    21901 gacaaagcat gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga
    21961 ttgaagacta gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta
    22021 gttctttttc ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca
    22081 aaaacaaagt acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg
    22141 aaagaaatga gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata
    22201 agagagatac aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt
    22261 tgcgctgatt gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga
    22321 atatcgaaag tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt
    22381 ttatttattg tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc
    22441 ccaaatgaca gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga
    22501 caacacggta ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt
    22561 atttttggaa ccagctttta atgttttatt actcatacca tttggcattt atttaagata
    22621 ttatttccgg ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt
    22681 tgaattgacg cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga
    22741 tgtgaatgat ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt
    22801 atttacattt atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa
    22861 gactgtctca ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct
    22921 tattaatttg gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc
    22981 tcatatctgg tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac
    23041 caatggatgg acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga
    23101 acgaatttct ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg
    23161 tttaagctgg ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt
    23221 gcagatgagt gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt
    23281 aaatatcttg ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca
    23341 cacatatact gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag
    23401 caaaaacgct ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc
    23461 acgaatgaat aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc
    23521 aaagggcttc aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg
    23581 aaaaaatatc attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc
    23641 tttgtttgaa aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag
    23701 tagggaacta gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc
    23761 ggagatccgt gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct
    23821 gcatcaccaa cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa
    23881 tgaacaagcg ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac
    23941 attggatatg ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct
    24001 gcagttttta gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata
    24061 catggaaaat ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga
    24121 aaattggctg atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac
    24181 aattggtcat ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat
    24241 tgccgattac ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc
    24301 aagagagaga aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc
    24361 gactgattta gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga
    24421 aattccagaa gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt
    24481 aaaaggaacg gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga
    24541 aaaattgggc gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata
    24601 cgatcgtaat agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat
    24661 tggtcttgtg aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg
    24721 ggcaattgca gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac
    24781 tgctcgtaaa aataagaaaa attcacataa ataaaaaaca agaggttgtg acaaaaggcg
    24841 tgtcacaatc tcttgttttt aagctagact ttttttcatt ccgatacaaa gtacttcatc
    24901 ttcaataaaa ggttctgtgc aagtatgata cccttgtttt tcataaaaat ctacagccgt
    24961 catttcagct actacataac tagtctgaca accttctgaa accgcccgtt tttcagcagc
    25021 ttcaagcaac tgaccgccta acccttttcc tcggtattct tttgctacgc aaaatcgttc
    25081 cggcttgaag caagtaggtg ttttcttttc ataacgcaaa gtagctactg gtcttttttg
    25141 atcaagaaat agataatagg tttgttgcgg gatatctttt ccgtcgaatt ctagttctgc
    25201 aggaatccct tgttctaata caaaaacttg atatctcaaa aagcagctag ctgcgcgtat
    25261 ccattcatcc gctccaacta tttttttcat catattcctc cttgtcatga atagcagaga
    25321 tgtattgatt cctttattct tatcgtacca aaaatcgtgg agtatgacca aaaggaaatg
    25381 aaaataaaaa ttgagatatt gacagtgatc aatagaatgc gtatactaat taagtacgaa
    25441 aaggatatga tttgtttttt aagactcaca gaaaattctt tcttggctga aaaaagaata
    25501 gtcactaatc aaattgctcc ctttttctat tttggtagaa ataccgacgc agctcagcgt
    25561 tatcgagttt aagaggtaat gattacacat cattgcaatc aaggtggtac cgcgagtttt
    25621 cgtccttggc tgtgatggtg tttttttgta tttaatttat agaaagcagg taatgacatg
    25681 aaacaattaa gtagtgcaca agttcgacaa atgtttcttg atttcttcca atctaaagga
    25741 catacgattg aacctagtgc gtctttgatc cccgtgaacg atccaacctt attgtggatc
    25801 aactctggtg ttgcaacatt gaaaaaatat tttgatggtt cagttgtgcc agaaaatcca
    25861 agaatcacaa atgcccaaaa atctattcga acaaatgata tcgaaaatgt cggtaaaaca
    25921 gcacggcacc atacgatgtt tgagatgctg ggtaattttt cgattggtga ctatttcaaa
    25981 aatgaagcca tccactgggc atgggaattt ttgactgatc caaaatggat ggcattcgat
    26041 ccagaaaaac tttatgtaac agtttatcca aaagatacag aagcaaaacg catctggcat
    26101 gaagaagttg gcctgccact agatcacatt attgatgtag aagacaactt ctgggatatc
    26161 ggtgcaggcc catgtggtcc ggatacggaa attttctatg accgtggaga agcttataac
    26221 gatttagcag aagacgatcc tgaaaactat ccaggaggag aaaatgaacg ttatttagaa
    26281 atctggaact tagtattttc agaattcaac cataagcctg ataacacatt tgaaccactt
    26341 cctcataaaa acattgatac ggggatggga ttggaacgca tggtctcaat cgttcaagat
    26401 gcgtcaacga actttgagac agacttgttt atgcctatta tccacgccgt agaaaagcta
    26461 agcaaacaag taaaatatgg tgaaaaccca gtaacagata tttcttacaa agtaatcgca
    26521 gatcatattc gcgccctttc atttgctatt ggcgacggtg cattgccatc gaatgaaggg
    26581 agagggtatg tcttacgccg tttgcttcgt cgtgctgtca tgcatgggaa aaaattaggt
    26641 attgaacaag cattcttata tcgtttagtc cctgttgttg gggaaatcat ggtaagttat
    26701 tatcctgaag tacttcaaca aaaagaattt attgaaaaag ttatccgtac agaagaagaa
    26761 cgtttcaatg aaacaatcaa tgaaggtttg gaaatcttaa atcaagtgat ccaagaagta
    26821 aaaaacgaaa acgggacgac tctagcagga aaagacatct tcaaactata cgacacatat
    26881 ggcttcccgg tagaattaac ggaagaggtg gcagaagatg aaggactgaa agttgatcat
    26941 gctggttttg aaaaagaaat ggatgcacaa cgcgaacgtg ctcgctctgc ccgcagtact
    27001 gaaaaatcaa tgggggtaca atctgcttta ttgacagata tcaaagtaga aagtaaattc
    27061 attggataca cagaacaaga atcagatagt caattattgg tcatcgttaa aggtgagtct
    27121 cttttgaatg aagtcgcaga aggtgaagct caaatgatct ttgatcaaac acctttctat
    27181 gcagaaatgg gtgggcaagt agcggatcaa ggatggatca tgaatgaagt aggcgaaatc
    27241 gtagcagttg ttacagatgt tcaaaaagcg cctaatggtc aatttatgca caccgtagaa
    27301 gtaaaagcac caatgagtga aggacaaacc tatcatctat tgatcgatca atcgatgcgc
    27361 aatcggatca tcaaaaacca tacagcaacc catctactgc acaaggcatt gaaagaagta
    27421 cttggcgagc atgcaaatca agctggttct ttagtcgctc ctggacattt acgattcgac
    27481 tttacccact ttggtcaaat cacttcagat gaattagctg aaatggaaag aatcgtcaac
    27541 gaaaaaatct gggaagctat cccagttgaa acaattgaaa cagatatcga tacagccaaa
    27601 aacatgggtg caatggcttt gtttggtgaa aaatacggac atgacgttcg agtagtaaat
    27661 attggcggct ggtcaatcga actgtgcgga ggcacacatg tagcaaatac agaaaacatc
    27721 ggaatcttca aaatcgtttc tgaatcagga attggtgcag gcgtgcgacg aatcgaggct
    27781 gtaacaagta aagaagcgta cgaactactt gaagaagaag aaaaacaact aaaacaagta
    27841 gcaacaattg ttaaatcacc tcaattgaaa gaagttgttt caaaagcgga acaattgcaa
    27901 cagcaagtaa gagagctaca aaaggaaaat gaacaattag ctagcaagtt agcgaatcaa
    27961 caagctggtg atgtattcaa agatccagaa acgatcaatg gaaaaacaat cattgcagca
    28021 caagtaaaag tgaaagatat gaatcagctg cgtcaattag ctgaccaatg gaaacaaaaa
    28081 aatatttcag atattcttgt tttagcaaac gaacaagaag gaaaagtcag tctgctagcg
    28141 gcaatgacga aagaatcaaa tgaagctgga ctaaaagctg gcgacttgat taaagcaatc
    28201 gcaccgaaag taggcggtgg cggtggtgga cgtccagaca tggcacaagc tggcgggaaa
    28261 aatcctgctg gtattccaga tgcacttaaa gctgcgaaag aatgggttgc gcaacaatag
    28321 ggcgtttacg tttgacagaa aaacaaaagt tcaaacattg aacgaaacat gattatgggg
    28381 gcgaagacaa acaagtcttg ccctcatact tttttcaatt ggatggcgca tctaatcaaa
    28441 tggtcggatt cggatggtct ttagttgacg aaagtgacag aaatttttac gattagtata
    28501 aataaaaagg ggtgaaaaaa tgaatagtag aaataagacc tttcgactag tcttacgtgc
    28561 gatcttgtta gcaatcatca tcgtacaagc gatggttcct tggctggggt ttattccatt
    28621 aggattcatt agtttaacaa ttatccatat cacagtaatt attgctgcag tagtattagg
    28681 cccaaaagat ggcatggtga ttggcttgtt ttggggaatc gctacaattg ttcgtgccta
    28741 tgccatgcca acaacgccat ttgatacatt agtgttcacg aatccgatta tctcggtagt
    28801 tcccagagta cttgttggct tagtagcagg cttggttttc cactggattt atcaaaaaaa
    28861 taaatcaata acgatcagct cagcctttgc aggggtactg ggttcattgg tcaatacagt
    28921 cttagtgtta ggattcatgg gattatttta tacaggtgca acggcagatg cctatggtgt
    28981 agactctgct cttttattta aaaccttagc aggggttgca gcaatcaatg ggataccaga
    29041 agcaataggt gcgggaatca taacaccatt actagcaaaa gcgttatttg cagcaacacc
    29101 gttgaaacca gaataatgac catcttttaa tagtaatagg acgcacgata gatagaaaaa
    29161 ggaagagagg agaggaaaac aatcgtcctc tccatctttt tacctgagca acaagcaaac
    29221 tagaaggggt aaaaaacttg gctaagaaac aagaagaaaa aaagaaacaa ataccgcaac
    29281 agcggacaaa aaaaggagta ctagcgggta tcttaggatt ggttacgaat ctgatcttgt
    29341 ttgtctctaa gctaatgatc gggctttttt caggaagtgt ctccattatg gctgatgcag
    29401 tgaacagtct atcagatact gcttcatcca tattgacttt gatcggattt aaaattgctg
    29461 caaagccagc agatcaggaa catccttatg gacacgaacg cttcgaatat atcagtgggt
    29521 tatttgtttc gatcatcatt acttatgtag gatttcaatt tttagagtct tctgctgaaa
    29581 aaatcatcca tccagaaaat gtctctttaa cacccatcgt cttttttgtc ctaatcattt
    29641 ccatcttttt gaaatttgca caaggcaaaa tgtatcaggt tattgcgcaa tccattgatt
    29701 ctgaaacatt gagagctaca gcaacagata gttataatga tgtctttact acactggctg
    29761 tattgctttc agcagcaatc gaatgggtaa ctggatggcg tattgatgga tatataggtt
    29821 ttgctttagc attatatatc ctttatagtg gattgacgat gcttcgaaat tttgtatacg
    29881 aactattagg aagtcgccca acgccagcag agattgaaga aatggaagag catttaaatg
    29941 cttgcgatga tatacttggc tatcatgatt tattggtgca taactatgga cccaataaac
    30001 gctttgcatc agtccacatc gaagtagatg aatcaatgaa tttgaatgtg gctcataaga
    30061 ttattgatct gatagaaaaa gactttaaaa agtctttgga tgtggaactt gtctgtcact
    30121 tggatccaat gcctgttgat aacgaaaaat actataatat cttgcggcag ttaaagcaaa
    30181 ttcttcttga aacaggtaca gggcttaata ttcatgattt tagagtaatt catcaaggaa
    30241 aaacgctgca atttgatgta gtggtccctg agaaattcca gtttgttgat acagaactag
    30301 aaagaatctt acgtagtcaa atagaagaaa aaatcggaga ttaccaattg gaaattacgt
    30361 ttgatcacaa ttatctttta tattaaatga gaaactataa aaagactcct taaagttttt
    30421 aatttaaaga gtcttttttt cttttaattg tttatggaga gcctgacgtg caagattatc
    30481 tgctccttta tttttgtttt cgggcaacca ttgcaggatc aataaagaaa attcggatag
    30541 aagttcttgg attctttgaa ggtagggaag gaagagctcg ttcttcgttg cgtttttgtc
    30601 gaccgtagaa actagtgttt tgctgtctga aaaacagaaa atcgtttcat tctgtaagtc
    30661 gtttttcttt agaaattcta aagtttttaa aaagacttcg aactctgctt gatggtttgt
    30721 ccctatagaa agcgggatag atagctgttc ttgtttacct tgatagacaa tcaagattcc
    30781 acctccacta ggaccagggt tgccttttgt agaggcatca atgtatactt ttaacataaa
    30841 aagagattct cctttttgtt caaactaatg ttatggtaag attatatcat tactgaatcg
    30901 gtgagaggtt agagaatgaa aaaaaatatt cgatggcagc ctgaactggc acatacgatc
    30961 atctattggt cattgacctt gatcattctg ttttttagtc tgattctttc tttagaaaac
    31021 acaggtcctt attggaaaag caattttgtt ttaggtattt ttcttgtttt tctatttcta
    31081 ggtttgcggc gttcttttat tttaaaatca aactctgtga ttatacgtta tgctgctttt
    31141 tggaaagacc gagaaatatc tgtcggacag attcgatctt tgacgccaac taatactggg
    31201 gtgcaaatga tgttgcaaga tgagaaagcc ccatctgttt tcatgatgcg aaaaaaagat
    31261 caagtagtcc tttttgatca ttttgaaaaa aacggaccca aatcagaatc aattccttat
    31321 ccttatacga aaaaaagaaa aagctaattt taaaaatcag aacctaaaaa aacgaatttt
    31381 tacaggaaaa gaaaagagtg agacgtacgg ttcatcccgt ttagcgtctc actctatttg
    31441 tttatctatt catgcatact agtatcggta gtctgaacgt tgcctttctt gacatgggca
    31501 gcttgtgttc ctcgattccc ttcgatgatc tcaaattcga ccacttgatt ttcttccaaa
    31561 gttttgaatc cctcttcttc aatcgcagta aaatgtacaa aaatttcttc tgtgtcatca
    31621 taactgataa agccgtatcc ttttttgttg tcaaaccatt ttacaattcc tgtggtcaaa
    31681 gcactcacga cctttctaaa gtctgatcat agccttcatt ataaagagta tttataagta
    31741 cgtcaaataa attaaaaacc tgtaatttta tgtttttttt ctgaataaaa aaaggtataa
    31801 ttggcatatc ttaacaaaga agatattttg ttgaataaag ttcgtgaaaa ggggtaatca
    31861 aatgaagaat gatctgcaaa tttcacaaga aacagagcta gaaccgattg ttgaagtggc
    31921 tagtaaatta gatcttaagg aagacgattt ggaactgtat gggaaatata aggcgaaaat
    31981 caatttttct ggaatcaatc gatcaaagga taacgctgag gggcatttga tcttagttac
    32041 ttccatcaat ccaacaccag ctggcgaagg aaagtcaacg atcactgtag ggttaggaga
    32101 cgcgctcaat aaaatcaata aaaaatctgt tattgcattg cgagaaccct cacttggtcc
    32161 tgtgatggga atcaaaggtg gtgctgcagg cggaggatat gcacaggtat tgcctatgga
    32221 agatatcaac ttgcatttta ctggtgacat gcatgctatc acaacagcta ataatgcatt
    32281 atctgctctt ttagataatc atattcatca aggaaatgaa ttgaacatcg atgcccgccg
    32341 agtgatttgg aaacgggtag tcgatctcaa tgatcgtgaa ctgcgtaaag taattgttgg
    32401 cttgggtggg ccaatccaag gtgttccaag agaagatggg tttgatatca cagttgccag
    32461 cgaaatcatg gctatcttgt gtcttgcggc agaccttgaa gatttaaagg ctcgtcttgc
    32521 aaggatcgtt gtcggctata catttgaccg tcagcctgtg actgctggag acttgaaagc
    32581 agaaggcgct ctggcattac tgctgaaaga tgcaatcaag ccgaatcttg tacaaacaat
    32641 ttacggaaca ccagcttttg tccacggggg accgtttgcc aatatcgctc atggctgcaa
    32701 tagtatttta gctaccaaga cagcattgag attagcagat tacgttgtca cagaggcagg
    32761 atttggtgca gatcttggcg gagagaaatt tttagatatc aaagtaccta acttgaaaaa
    32821 agcgccggat gctgtggtga ttgtcgccac tgtccgtgca ttgaaaatgc atggcggaat
    32881 gaaaaaagat gaacttaaaa atgagaatct tgatgctttg aaagtaggtt ttgcaaattt
    32941 aaagcgccat atacgtaata tggaacaata tcagctacct gtgatcgtcg caatcaatga
    33001 attcgtaaca gatacagaca atgaactcac actgttggag cacttgtgtg aaaatcaggg
    33061 gattcttgcc aagagagcga gtgtatgggc agatggagca gaaggcggcg ttgatttagc
    33121 aaaagctgta gtacgattga ttgatagaaa agaagctaat tacaagccat tataccgcct
    33181 agaagaaacg atacaagaaa agacagaaac aatcgtcaag aaaatttacg gaggaaatgg
    33241 tgttgttttc agcaaaaaag cgcaaaaaca aatagaagag tttacgaaga atggatggga
    33301 caaactgccg atttgtatgg caaaaacaca gtattcattt tctgatgatc cttcactgct
    33361 aggtgcaccg gaagatttca ccatcacgat ccgcgaaatc atcccaaaat taggggcagg
    33421 atttttagta gccttgactg gagatgttat gacgatgcct ggtttgccta aaaaacctgc
    33481 tgcattgaat atggacgtga caaatgacgg agaagtgttg ggattgtttt aagcttgatt
    33541 ataatctacc atcgaaggag ctgtattttg actacagctt ctttttttag acgataggga
    33601 attaattttg tttacactag gatcattctt tttctttatt gtattttgag ctatactaaa
    33661 gcataatagg agggtatgat gaaaacgaca tttataagaa aaaccggttt ttacggtatg
    33721 ggtagctcga ttcagctaag aatcaacaat gaaaaacgca gtgttctcag tcatgaacaa
    33781 aagataacgc ttgatctgga agtgcccttt acgatgcagg tcacctttta ttggctaaaa
    33841 agccccgttt atacagtgaa agaagcaaag cctgcttatg tgatcacaat gaattacttg
    33901 attcttcaaa tctatccgtt tttatttcta gcaactgggt tgggggccgt tttcctacaa
    33961 aatttatttt tcagtttttt tgcagttatt gtgttgattg cgttcttttt ctatataaaa
    34021 aaccgggcat atttgatcaa ggaggaaaat tatggcaaac tctgatcttt ttttaatcag
    34081 tttcaatcga atcgaaaaat ggatgagaga cgagatggga aatgcacgaa atatgggatt
    34141 taccgaactt gtcagacgcc tagctcaaag aaaacaatta atgatcagaa aatacgaaga
    34201 tgatctttta cagcttgctc agttaaggaa tgcgatcgtc catgatcgga tcgcagtcga
    34261 ttttgtcatt gcagagccaa atgattggac agtcaagcga atccagctga tcgaacaaga
    34321 actgattcag cctgaaaccg tgctgcctcg atttgcaaaa cgtgtaacag gttttgaaca
    34381 agatcttccg ttacttgaac tgttaaagat agtagcagaa aaaaggtatt cacaatttcc
    34441 gttatacaat aaaggaaaat ttgtagcatt gattacttta cgtaatatcg ggttttggct
    34501 agcaaaagaa agccaaaaag gtccggttga tttaacaaat aaacgagcgt tggatttgat
    34561 catccaaaac ggaaagtaca caaattatca ttttgttcca gctaaaacac atatttacga
    34621 ggttgaagcg atgtttcgtg agcaagggac tttggaagcc gtacttatca ctaaagatgg
    34681 gaatcccgat ggtaatctgc tcgggatcgt acgacctcgt gatatttata aacaaataga
    34741 aaaggattga ttttttgtta attatttatt ggatattcag cgctttgcta gtaggagtgg
    34801 atcagttggt caaatggtgg atcactgata atctagcgct tggagagacg aaaaatctta
    34861 taccaggtat tttgtcactg aatcatattc gaaacactgg agccgcatgg agtatgctag
    34921 aagggaagat gtggttcttt actatagtga cactcattgc agtcgttgtg attctcacat
    34981 tgatgattaa aaatcgtgaa aaaggtaatc gctggttcat gattggattg agtttgattc
    35041 tagctggtgc gattggcaat tttatcgacc gtattcgtct tggctatgta gtagatatgt
    35101 tccagacaga ttttatgagc tttccgattt ttaacgtagc agatgtgaca cttgtatgtg
    35161 gagtgatttg tatgttaatt tatattattt tagatgaaaa ggatcaaaga aaaaaatgac
    35221 agaacttaaa acgacgattc accatgaatc tggtaggatc gataaagtat tgactaattt
    35281 attcaccgat tacagtcgtt cgcaaattca gctgtggctg aaaaatggag cggtttctgt
    35341 caatggacag ccagtcaaag caaattacaa agtaaaacaa ggagacgaga ttactgtctt
    35401 gatccccgaa ccagaaacat tagatgtggt cccagaaaat atcccgttga cgatcgttta
    35461 cgaagatgaa gatgtagcgg tgataaacaa acctcaagga atggtcgttc atccttcagc
    35521 aggtcatacg catggcacaa tggtcaatgc gctgatgtac catatcaagg atctttctac
    35581 gatcaacggc gttattcgtc caggtattgt tcaccgaatc gacaaagata cttccggact
    35641 gctaatggtt gccaaaaatg accaggcaca cgaatcatta gctcagcaat taaaagataa
    35701 gacctctttg cgcaaatatg ttgctttagt ccatggagag attcctcacg aaaaaggaac
    35761 catcaatgcg ccaatcggcc gttcgaagga aaaccggaaa atgcaggcga taagagaaga
    35821 tgggaagtcg gctgtcacac attttactgt attggaacgt ttcgaaggat ttactctggt
    35881 tgaattaaaa ctagaaaccg gaagaacaca ccagatccgt gtgcatatga agtatatcgg
    35941 ttatccgtta gctggagatc cagtatacgg accgaagaaa actttgaaag gcaatggtca
    36001 gtttctccat gcgcaaatgt taggttttac gcacccgact acaaacgaaa agatgatctt
    36061 tgaagcacct cttccagaag tttttgaaaa aactttagaa aaattaagaa aaaacattgc
    36121 attttaattt agataacggt atagtaatta acaacgaaag cataaaactt aatagaattc
    36181 ctttaagttt agtcccgtga ggctaagaag ggtgggagca aggatacgta tggtgcgcca
    36241 taagtagatt gctcattgac atagtatagc tatcagtgta tcagtatacg ctcagtctaa
    36301 acattcctcc tgtcctctta gggcaggagt ttttttatgc aaaaaagtag ggggaatgaa
    36361 aatgcaagca aaagaagtag tagatcaggt aaccatgaag cgagcattga ctcgaattac
    36421 ttatgagatt atcgagagaa accatagtat ccaagatatc gtattggtag gtatcaaaac
    36481 acgaggaatc tacattgcat caagaattgc cgaacgcctg aagcagctag aagatatcga
    36541 tattcctgta ggagaactgg atatcacttt ataccgagat gacaaaaaag aaaatccaga
    36601 agaaccggaa cttcattctt ctgacatccc agtttcctta gaaggaaaag aagttatttt
    36661 gattgatgat gttttgtata caggacgaac gattcgagca gcaatggacg cagtaatgga
    36721 ttttggcaga ccaagaaaaa tttcattagc agtcctggtc gatcgtgggc atcgagaatt
    36781 gccaatccgt gcagattatg ttgggaagaa cattccaaca tctcgggcgg aagagatttt
    36841 agtagagatg caagagcttg atggacaaga tcgcatcatg attttgaaag aggaagatta
    36901 gaggagagag aaacatgtcg gagaaaaaag gatttcataa tgatgacgtg gtgttagata
    36961 tccacgatcg cccaacccca ggacattggg taggattaag tttacaacac ttgttcacga
    37021 tgttcggagc aaccgtgtta gtccccatct tagtaggtat cgatccaggt attgcgctag
    37081 tcagttcagg actaggtaca ttggtgtact tatttactac taaaggaaag atacctgcgt
    37141 acttaggaag cagcttcgct ttcattgcag cgatgcagct tttgatgaaa acagatggtt
    37201 atccagcgat tgcacaagga gcagtcacaa ctggattagt ctatttgatt gttgcgctga
    37261 tcatcaaaaa gatcggttca gcatggctgg ataaaatctt gcctccaatc gtcgtcggtc
    37321 cagtcatcat ggttatcggg ttgggacttg cggcaaatgc agcaacaaat gctatgtata
    37381 atcagggcac gtatgatttc aagtatattg ctgtagcgct gatcacatta ggattaacaa
    37441 ttttcttcaa catgtggcta agaggttttc tcggattgat tccgatttta ctaggtatta
    37501 ttagcggata catcgtagcc ttgctgtttg gaatcgtgga tactaagcca atcgtagacg
    37561 ctgcctggtt tgctgttcct aactttgaga ttccctttgt acaatatgaa ccaaagctat
    37621 atcttggagc aatcacaaca atggcaccca tcgcttttgt gacgatgaca gagcatatcg
    37681 gccatcttat ggtattgaat aaactaacta aacgtaattt ctttgaagaa ccgggtcttc
    37741 ataagacgtt gacaggtgat ggattagcac aaatcgtggc agcctttgtc ggaggtcctc
    37801 ctgtaacaag ttacggtgaa aacattggtg ttctggctat cacacgtgtc catagcgtgt
    37861 ttgtgatcgg tggagctgca gtatttgcag tcattttagg attcgtagga aaattaagcg
    37921 ctttgatttt aagtatccct ggaccagtca tctcaggaat cagttttatc ttatttggag
    37981 taattgccgc aagtggaatg aagattttaa tcgagaacaa aatcgatttt gataaaaaga
    38041 aaaatctgtt gattgcttca gttatcttag tagtaggaat tggcggactc gtctttgaag
    38101 taggcacatt tacattgtcg gcaatggcat tagcaactgt acttggcatc attttaaatc
    38161 ttatcttacc agaaacttca cgaagcgaag aaaactaagg aggaaacatt atgatcatca
    38221 aatcagaacg tatcagctta aagcatttat tgaccgttga ggcacttact gatcaagaag
    38281 ttatgggctt gatccgcaga gggcaggaat tcaagcaagg tgctaattgg actccgcaaa
    38341 agcgccagta ctttgctaca aacctctttt tcgaaaatag tactcgcaca cataaaagct
    38401 tcgatgtagc ggagaaaaaa ctagggctag aagtgattga atttgaagca agcacaagct
    38461 ctgtccaaaa aggggaaaca ctatacgata cagtactgac gatgtcagca ttaggcgtag
    38521 acgtagcggt tatccgtcat ggtgatgaga actattatga cgaactgata caaagtaaaa
    38581 caatccagtg ttcgattatc aatggaggag acggaagcgg acagcatcca acccaatgct
    38641 tgcttgattt gatgaccatt tatgaagaat ttggtcattt tgaaggtctg aaagttgcca
    38701 tcgtaggtga tatcactcac tctcgcgtag ctaaatccaa tatgcagatg ttaaaacgtc
    38761 taggcgcaca agtattcttc tcaggtccta gagaatggta cgacgatgaa ttcgaagtgt
    38821 acggacatta tatgccattg gatgaactac tagatcaagt tgatgtcatg atgatgcttc
    38881 gggtgcaaca cgaacgccat gatggaaaag aaagtttctc aaaagaaggc taccatcagg
    38941 aacatgggtt aacagttgag cgtgcgaaga agttgcaaaa acatgcaatc attatgcacc
    39001 cagcaccagt taaccgtgat gtagaattag ctgattcatt agtggaagga ttacagtcgc
    39061 ggatcgttca gcaaatgagc aatggagtat tcgtcagaat ggcaatctta gaagcagtgc
    39121 taaatggaaa agcgtaatta taggaggatg aaaaaatgaa aacactcatt aaaaacggtc
    39181 agatcaatac acgaaaaaat atgacgacac cagcagaaat ttggatagaa gatgggcgaa
    39241 tcaaagcaat cggtacagga ttctcagaag ccgaatttga tgaagtgttt gatgcaaagg
    39301 gacaattgat cacacctggt ttagtggacg tccatgttca tttgagagag ccaggattta
    39361 catacaagga gacgatcgaa gctgggactc gctcagctgc tcgtggcggt ttcactactg
    39421 tatgcgcgat gccgaattta aatcctgtac ctgatacggc agaaaagctg agacaagtat
    39481 atgacatcat tagaaaagat gcagttgtga aggtattgca gtatgcgcca atcacagaaa
    39541 atctgcgaag tgagaaatta gttgatcaag aagcactgat tgaagaaggt gcttttgctt
    39601 tcacaaatga cggtgtaggt gtccaaacag ctgggacgat gtatctggct atgaaagaag
    39661 ctgcaaaaaa caataaagcc ctagtagccc atacagaaga tgaatcttta ttatttggcg
    39721 gcgttatgca cgctggcaag aaggcagaag aacttggtct tcccgggatc ttaagcgtaa
    39781 ccgagtcttc tcaaattgct agagatctgt tgctagctga agcaactggt gttcattacc
    39841 atgtttgcca tgtttctact aaagaaagtg tccgtgtaat cagagacgca aaaaaagcag
    39901 gaatccacgt aacagcagaa gtttcacccc atcatcttat tttgatcgac gaagatattc
    39961 ccgaagattt cggcttttgg aaaatgaacc cgccgctaag aggacgggag gacagagaag
    40021 ctttgatcga aggcttgctt gacggtacga tcgattgcat cgctacagac catgcccccc
    40081 atggattaga agaaaaaagc caaagtttca tgaaatcacc atttggtatc gtaggaagcg
    40141 aaacagcgtt tcaactgatc tatactcatt ttgtagaaac tggtcgattc acgttggaac
    40201 aagtgatcaa ttggttggca gttaaaccgg ctgagatttt tggtttgaat gcaggaacgc
    40261 taacggttgg tgcccccgct gatgtagcag tttttgatat tacacaaact tgcacgatcg
    40321 ataaagaaga ctttttatca aaaggggaga atacaccttt tatcggctgg aaagtaaaag
    40381 gcgaaacaca aatgactttt gtcaacggaa aacttgtgtg gcagaaggga gaataaaagt
    40441 atggaacgtt tgcttatatt agaagatgga acagttttcg aaggaaaggc ttttggtgca
    40501 gatgctagtg tcttcggaga aatcgttttt acaacaagta tgactggtta tcaagaaact
    40561 atcactgatc aaagttttaa cggtcaaatc attacattta cctatcctat ggtgggtaat
    40621 tatggggtaa atagagatga ttatgaatcg atttctccaa catgcaaagg agtagtagta
    40681 aaagaacatg cacgtgtagc ttcaaactgg cgaaaccaaa tgacgctaga ttcatttttg
    40741 aaacaaaaag gaattcctgg aatatcaggt atcgatacgc gcgcccttac tcgcaaaatc
    40801 cgtgaagtcg gaacgatgaa agctagtata gttgatgctg gagattcctt cgaacatgca
    40861 tttgatcagc tgaaagcaac cgttctagca accaatcaag tgcagcaagt ctcaactaac
    40921 aaaccttatc caagtccagg aacaggtcgg aaagtcattg tcattgactt cggcttgaaa
    40981 catagtattt tacgagaatt gagtaaaaga aactgtaacc tcacagtact tccctataac
    41041 acagatgccg agacgatttt agcgctatca ccagacggag tcatgctgac gaatggacct
    41101 ggtgatccaa aagatgtgcc agaagcaatc gaaatgatca aaaaaatcca aggaaaagta
    41161 ccgatttttg gtatttgtct cggtcaccag ttatttgctt tagccaacgg tgcagatacc
    41221 tataaaatga aattcggaca tcgaggatta aatcacccgg tacgagaagt agcgaccgga
    41281 agaattgatt ttacttctca aaatcatggc tatgcagtcg atgaagccac gattgatcca
    41341 gaaaaactca tcgtaactca tgtagaagta aatgacggaa cagtagaagg agtcaaacac
    41401 agagattatc ccgctttcag tgtgcagttt catccagatg ctgcccctgg tccgcatgat
    41461 gcactacatt tatttgatga atttatggaa atgatggacg caggaaagga gcagtaaaca
    41521 gatgccgaaa cgtacagata tcaagaaaat tatggtgatt ggatctggtc cgatcatcat
    41581 tggtcaagcc gcagaatttg actacgcagg aacacaagcc tgccttgcct taaaagaaga
    41641 aggatatgaa gtggttttag taaattctaa tcctgcgacg atcatgacgg ataaagaagt
    41701 ggcagatcaa gtatatatcg aaccgatcac acttgaattt gtatcaagga ttcttcgaaa
    41761 agagcgtcca gatgctctcc ttccaacttt aggcggacag acaggcctca atatggcaat
    41821 ggagctggca gcatcaggta ttttagaaga attgaacata gaacttctag gaacaaagct
    41881 ttctgcgatc gatcaagcag aagatcgtga tctattcaaa cagttgatga aagaattgaa
    41941 tcagccaatc cccgagtctg aaatcgtcaa tacagtagaa gaagctgtag attttgcaaa
    42001 taaaatcggc tatcctgtca tcgttcgtcc agcctttact ttaggcggaa ctggtggagg
    42061 tatgtgtgaa aatgaagaag aattacgtat cgtatcagaa aatggattaa gtctttcccc
    42121 cgctacccaa tgtttgattg aacgaagtat tgcaggtttt aaagaaattg aatatgaagt
    42181 gatgagagat tcggctgata atgcaatcgt tgtctgcaat atggaaaatt ttgacccggt
    42241 gggtatccat acaggtgatt ctatcgtatt tgcccctagt caaacattgt ctgaccatga
    42301 atatcaaatg cttcgtgatg cttctctttc gattattcga gcacttaaga tcgagggagg
    42361 ctgtaatgtc caactcgctc ttgatccaca tagttttaat tattatgtga ttgaagtcaa
    42421 tccgcgtgtt tctcgttcat ctgcgttagc aagtaaggcg actggctatc cgatcgctaa
    42481 gctagctgct aaaatagcgc ttggattaac attagacgaa atgaaaaatc ctgttacagg
    42541 aacgactttt gcagaatttg aacctgcatt agattatgtt gtagctaaaa ttcctcgctg
    42601 gccgtttgat aagtttgaaa acggagaacg gcttttaggc acgcagatga aagcaactgg
    42661 tgaagtgatg gctatcggtc ggaatatcga agagtcttta ttgaaagctg tgcgttcttt
    42721 agaaatcggt acacaccata tcgaacttcc tgagttggca gacatcacgg acgatgacct
    42781 aatccaaaaa gtggttcgag cacaagatga tcgcctgttt tatgtagctg aagctattag
    42841 aagagggtac accatagaag aattagcgga tttgacaaaa atcgatttat tctttttaga
    42901 taaactgttg catatcgtag aaatcgaaca gcagttgaaa cagcagccgt tggatgacaa
    42961 gatattgaaa acagcgaaac aaaacggttt tacagacaaa aaagtggcgg agctgtggga
    43021 aataaacgaa gaagccgttc gccagatgag aaaagaaaat gatttgattc ctgtatataa
    43081 gatggttgac acttgtgcag cggaattcga atcaaaaaca ccttattttt atagttccta
    43141 tgaatatgaa aatgaaagtt cacgatcaga aaagccctca attctagtac tgggatctgg
    43201 tcctatccgt atcggacaag gggttgaatt tgactatgcg actgtgcatt ctgtcaaagc
    43261 aatccagcag gcaggatacg aagcaatcat catgaacagc aatcctgaaa cagtttcgac
    43321 tgacttttct atttcggata aattatattt tgagccattg accttcgaag atgtgatgaa
    43381 tgtgatcgag ctagaacagc cgataggagt aatcgttcaa tttggtggtc agacagcaat
    43441 caacttagcc gaacctttga ctgctgctgg tgtaaaaatc ttagggacaa cgatcgaaga
    43501 cttggatcgt gcggaaaatc gtgatttatt cgagcaagcg ctgaaagagt tggatattcc
    43561 tcaaccttta ggggatactg ctacaagtaa agaagaagcc gtggttatcg cttcgagaat
    43621 tggttatcca gttcttgttc gtccaagcta tgtattaggc ggacgtgcga tggaaatcgt
    43681 tgaaaaccag cgagatttag aagattacat ggaacatgct gtgaaagcat ctccagaaca
    43741 tccagtacta gtggaccgtt acttgcttgg tggtgaatgc gaagtggatg cgatttgtga
    43801 cggtgaaaca gtactcatcc cagggatcat ggagcatatt gagcgtgctg gtgtccattc
    43861 aggggattca atggctgtgt atccacctca aacattatct gaatcgatca agaaaacgat
    43921 cgaagattac acgatccgct tagcattagg tttgaattgt gtcgggatga tgaatatcca
    43981 gtttgtcatc catgaaaatg aggtttatgt gatcgaagtc aatcctcgag caagtcggac
    44041 tgttccattc ttaagtaagg tgacaggaat tccaatggca caaattgcga cgaaagctat
    44101 tttgggagag aaactaaaga cacttggtta tgaaaacgga ctttatccag aaacaaaaga
    44161 agttcatgtt aaagcacctg tcttttcttt tacgaaattg cagaaagttg atacttactt
    44221 agggcctgaa atgaaatcga ctggagaagt aatgggatct gacagacaat tagacaaagc
    44281 tttgtacaag gcattcgaag cttctggatt acacttgcct gaatatggag ccgtattatt
    44341 tacgattgcg gacgaaacaa aagaagaagc actagaatta gctaaacgtt ttacagaaat
    44401 tggctatagt ctgataggaa cgaaacatac agctgcttat ttcgaaaaaa atggtctggt
    44461 cgttgaaaca gtagcgaaaa tttctgagga agcagcagaa aaaaatgtag tcgacttaat
    44521 aagagatggt aaaacacaag tggttgtcaa tacgattgat aaagatcggg gaaatgcttc
    44581 taaagacggt ttcatcatcc gaagagaagc agttgaacat ggtattccat tgtttacttc
    44641 tttagacaca gcagatgcga tcgttcgagt gatggaatcc cgtgcttttt caactaaccc
    44701 tatttaacgg cgagcacatg ttaagacaaa aagacgaaaa accgttgcag gaggggacag
    44761 atgaaacaag aaatgatgga aatcgttcag caaaaacagc tggcaccaaa gatttttgaa
    44821 atgacattga aaggtgatct agtaaaagaa atgcagcaac caggacagtt cttgcatatt
    44881 ctcgtgccgc gtgcagactt gctattacgc cgaccgatta gcttgaatca tatcgaccac
    44941 gaaacaaata cttgccgtat catttatcgg gtggaaggtg aggggactag agtcttctct
    45001 actctttctg ccggagacca tttagatgtc atgggtcctt taggcaatgg ttttgatttg
    45061 tccaatcttc atacaggaga cgaagtattt ataatcggtg gaggaatcgg tgtccctcct
    45121 ctatatgagt tatcaaaaca gttagtcgaa aaaggaatta agccaacgca ttttttaggt
    45181 tttgccacac atgaagtcgt ttattatgaa aaagaattta atcgtctagg agaaacaaga
    45241 atcgctactg acgatggaac atacggtatg cacggaaatg tcggtaattt attgttagga
    45301 acgaagacgg aacctacagc tgtttttgca tgtggttcaa acgggttatt gaagacagtg
    45361 gaacagctgt tttcttcgca tcaaaatgtc cagttatcat tagaatcccg catggcatgt
    45421 gggatagggg cttgctatgc ttgcgtttgt catacgccgg aagatgaaac aggaacaaaa
    45481 agtgtgaaag tttgtgacga aggaccgatt tttaaaatag gagaggtaat tatatgaatg
    45541 agaatccttt agcggtcaaa cttcctggcc tagaattaaa aaatcctatc atgccggcaa
    45601 gcggctgttt cggttttggc aaagaatacg gaaaatacta tgatttgaat cagcttggat
    45661 cgatcatggt caaggcaacg actccaaatg cccgctttgg caatcccacg ccaagagtgg
    45721 cggaaacacc atctggcatg ttgaatgcaa ttggtttgca aaatcctggt ctagacgttg
    45781 ttatgcataa acttcttcca gaattagagg agtacaatga gttacccatc atcgcaaatg
    45841 ttgctggtgc ttgtgaagaa gactatgtag aagtttgtag caaaattggc gaagcaccaa
    45901 atgtgaaagc aatcgagctg aacatttctt gcccaaatgt caaacatggc ggaattgctt
    45961 ttggaacaga ttctgatgtt gcttttcaat taacacaagc agtaaagaaa gtttcttctg
    46021 ttcctgtcta tgtcaaattg tccccaaatg taacagacat cgttccaatc gctcaggcaa
    46081 tcgaagctgg aggggcagat gggtttacga tgatcaatac tcttcttggt atgcggattg
    46141 accttaagac aagaaaaccg attttagcca atcaaacagg tggactctcc ggaccagcaa
    46201 tcaagcctgt cgctattcgt ttgattcacc aagtagcaag tatatccagc cttccaatca
    46261 ttgggatggg cggcgtgcag acagtggatg atgttcttga gatgtttatg gctggagcaa
    46321 gtgctgtagc tatagggacc gcgaatttca ccgatccgta tatctgtcct aaactaatta
    46381 aagagctccc tgtgcgaatg agcgaactag gcatcgaatc gctggaaaga ttaatcaaag
    46441 aagtgagaga ggaacgtgaa cgatgaatca actagaccaa cgaccaatta ttgcattaga
    46501 tttttcaact aggcaagagg tagaagactt tcttcgattt ttcccgaaag aagaaaaatt
    46561 gtttgtgaaa atcggaatgg aattgttcta ccaagaagga cctgaaatcg tacgttatct
    46621 aaaagaggct ggtcataatg tatttttaga tctgaaactt cacgatattc cgaatacggt
    46681 cgaaaaagca atgcggggat tggcaaagct tggtgttgat ctcacctgtg ttcatgccgc
    46741 tggcggtatt cgtatgatgg aggcggcaat gcgaggatta gaagagggga ctccagaagg
    46801 tggaaaacgt ccgctacttc tagctatcac tcagcttact tctacaagtg aagaagaaat
    46861 gcatgccgat caactaatcg aagtttcttt agaaaaaagt gtgatccatt atgctagctg
    46921 tgccaaaaaa gcaggattag atggtgtggt ttcttctgct tgggaagtag aagcgatcaa
    46981 agaaatggca ggagacgaat ttgtttgctt aactccgggt ataagaccag aaggaacagt
    47041 cgcaggagat cagacaagag tagtcacacc ttctcaggca aaaaagatcg gctcaacttt
    47101 tatcgttata ggtcgaccaa tcactcagtc aactaatcct tataaagcat atcaaacgat
    47161 tcaaacagaa tggagctaac ctaaaatgaa tgttgaacaa agtatcgcaa aagacttatt
    47221 agaaattgaa gcagtatttt taaatccaag taatcctttt acatgggcaa gtggaatcaa
    47281 aagcccaatt tactgtgata accgaatcac gatgagctat ccaaaagtcc gaaaagagat
    47341 cgcaaaagga ttagcaagca aaatcaaaga agcttaccct gaagtacaag tgattgctgg
    47401 aactgcaaca gcaggaatcc ctcatgccgc atgggtagcg gaaatactgg atttgccaat
    47461 ggtctatatt cgaagtaagg cgaaagatca tgggaaaggt aaccaaatcg aaggacgtat
    47521 atttgaaggt cagaagatgg ttgtgatcga ggatttgatt tctacaggcg gaagtgtctt
    47581 ggaagcagct gaagcagcaa aaagagaagg tgcggatatc cttggtgttg cggctatctt
    47641 tacgtatgag ttgccaaaag gaaaagcaaa tttcgaaaaa gccgaaatcc ctcttatgac
    47701 gttgaccaat tattctgtat tgattgaagc agctttagaa gatcgttata tcgatgagca
    47761 agaattaact ctgctaaaag aatggaaaaa agatcctgaa aattggcaga tttaagcgcg
    47821 cttgatgaag atagagaaat ccgatttgtg tctccagaat catcaattgg aatagcaaaa
    47881 atccaaaaac tgattgcgag aagcatcttt tcatcaggta tgaaaagaaa cttctatcgt
    47941 gatcagtttt tgattttttt aaaattcatt tttctaagac tggttagcag aaagaagaga
    48001 ataatctctt ctcttttttc tattatatat agattttctc tattttttgg taagggagct
    48061 gtttcaaaaa tggtaaagag cggaaatgtt gcgaatatca gttatttaat gatatgatat
    48121 tcggaaaaag aaatctcaaa gggaggtaac ttttatgggg ttgaatgaat ttattttagg
    48181 attgaacaat ttagagacga tcacaagggc acctggattt tttaaatata cagagcatac
    48241 agttgcagca cattcgtatc gtgtagcatc tattgcgcaa gttctaggag acattgaaga
    48301 agcgaatgga caaccgatcg attggaaact gctctatgaa aaatcattga atcatgacta
    48361 cacagagcgt tttattggtg atatcaaaac gccggtgaaa tacgcaagca aagagttaag
    48421 agggatgctg caaacagttg aagaaaagat gacggacgaa ttcatcaacc aagagattcc
    48481 agctgagttc caagaagttt atcgccgtcg gttgttcgaa ggaaaagatg aaaccgtaga
    48541 aggagaacta ttagccattt cagataaggt tgaccttctt tatgaatctt ttgatgaaat
    48601 catcaaaaat aacccggaaa aagtttataa ggagatgttc attgaggcag tgactacgat
    48661 taaaagcttt gaacatcggc cttctgttca gtatttcttt aaagagatat ttccggaact
    48721 attgaaccag gaattttatg gaaaagaggc gtttttagaa accgtctcaa cgattgtaaa
    48781 gaaagaagaa aaataaaaat gatatgagat gcagggggaa gtatagttga aaaagaatat
    48841 ggatgtcgaa tggggctatt ctggagacaa aggtccggaa aattgggcga gtttatgtga
    48901 ttggtttgcg agaggtgcgg aatttccatt gcagtcgcct attcatttga ccaaggggga
    48961 agaaaccaaa atagaaggag acacgctttc ctttcattat caaaagcaac ggtttactga
    49021 caaggaattc aaaaacacga ttcatttagt accttttgac caactcagtt atgtagagtt
    49081 caagaaagaa cgctattatt tgacagatat tcatttccac ttgccttctg aacatatcat
    49141 caacggaaaa caggaagata ttgaatttca ttttgttcat atgaacagca aaaaagagaa
    49201 tctagttgtg ggtgtcatgt accagctaat ggtacaggaa ggttggctgt ataatcaaga
    49261 aaatggggaa agttggaact tagaaaaaca tgagcattgg gtaaatccgg atgtgttctt
    49321 tccggagcaa aaaagccatt tccattatat tggctcattg acaactccgc ctaccagcgg
    49381 gccaatccaa tggtttgtaa tggatcatgt aggaaaactg aaccaagagt ttcttctccc
    49441 cttcgatggt cagtatgctc gaccgaacaa ccgaccaatc cagcccttga atggaagaga
    49501 aatttattat ttcgaggagt ttgagcaatg aatattcagc agatgaaata cgtggtcgct
    49561 gtagcaaaca atggtagttt cagagaagcg gcaaagaaaa tgtttgtctc ccagccaagt
    49621 ctttcagctg gtatcaaaga attagaaacc gagttaggga tcacgctgtt tactcgaacg
    49681 aatcgagggg catatttaac agaagaaggg caagacttct taaatcgtgc cgagaaaata
    49741 ttggtccagc ttgatacatt agaaactcac tatctaacga gtgaaaagag agacaatttt
    49801 tcgatcgctg cccagcatta tgatttctta ggtcctttga ccgcacagct actcgaggaa
    49861 ttcaaagacg agatcaaaca atttcggatc atggagacga caacagcgag agtgatcgaa
    49921 gaagtcaaag agcagcacag tgagatcggc attatttata tgaatgagca taatcaagct
    49981 ggtatcagaa gatatttaca acaaggagag ctaagtggcc gcagcattgg aaaattcaaa
    50041 acgcatattt ttttaaggca aggacatcca ttagctgaac acgcagagat caccaaagaa
    50101 gaattgttat cttatcctca agttcgtttt acacaggatg gaaataattt cccgtatttt
    50161 tatgaagacc ttatcgagat ccctgatcaa gaaacagtga tttatacgag tgatcgaggt
    50221 actttgatga atatcgttct tgaaactgat gcttacgctt caggatctgg tattgtgatt
    50281 ggagggattc gcgagcactt gcggttaatc cctttggcag aaggcgaact aaatgaattt
    50341 tatatcattt attcggcgaa acgtccgctc agtgaaatcg ctcaaagatt tatcaaagag
    50401 cttactcggt tactggacca gcagagctaa gaaaagcaga tgagaacgct gtttattgaa
    50461 caccgttgat caaaaaagag gggttgtgac agaattttgt cacaactcct ctttttgtag
    50521 caaacaattt ataactaatt gctgttgtgg gaaagtacgc aaatatgatt ctagaaacac
    50581 tcattgatta cctgttttgt ttcatagctg taattttttc ttcttctggt gtcacgataa
    50641 tcgtcttttg gttttcataa ataacataac caggcttggc gccatttggt tttcggatat
    50701 gctttacctg tacaagatca accggcactt gggcagagta tcggtatttt gaaaaatagg
    50761 cagctaactc ggcagcttct gtaattgttt catctgaggg cttgtcactt ttaatgatga
    50821 cgtgcgaacc gggtatattt tttgcatgaa gccaatagtc ggttttttta gctgtcttca
    50881 ttgtcagctg gtcattttga agattgtttt taccaacaag aatgagcgtt ccgtcagaag
    50941 aaaagtattg atcaggctga gatggtttct tacgtttttg tttttttaag ttcttctttt
    51001 tcaggtatcc ttctgaagtc aattcttctt taattgcttc gatatccatt gggccggcaa
    51061 tttccagttg agataagaca gattcaagat attggatttc atctttggct tcttggattt
    51121 gttcgccaat cagcttaaca gcgttcttca gcttttggta tcgatggaaa tatttctgtg
    51181 cattttgatt tggtgtcaat gccggatcta gtgctatttt gattggccga tcttcttcat
    51241 aataattagg taaaacaact tcttttgcgc cgcgtggtac ttgtgtcaga aaagtagtaa
    51301 gtagttcgcc atttctacgg taattctcag cgttttcgga ttctttgagt gtttgttcac
    51361 gttttttcaa tttattttta tttcgtttta gttcattttc gatttttcga atcagttctc
    51421 cgccttgttg ttttgcccga tctttctctg ctttttcgtg ataatagcta tctaataatt
    51481 gactgagtgt tggataagct gttacagcag atgcctgttc ggacaatacc tgataagcaa
    51541 tcggtgtgaa aaaatcttta ttttccgttt cgtaaaaagt aggaataggc tgatggctga
    51601 tggctgagaa aaattcgtcc catacaacca tcttttcatt aggacgttcc agtaatcttt
    51661 tggtcagctc ttgagcgata tcgaaaccga ttccctgaaa ctgacgttgg attgcttttg
    51721 gatctagttc agtttgggaa agccgctgaa agattttttc tttctcggag ctaaatgggt
    51781 tcaagacctc ttgttttggc ggagcaacat attctacacc aggaagcaaa gaacgataag
    51841 tgttttgaga gcttccaatg tgtttgatcg catccagtat ttttccagtt tctcgattaa
    51901 ctaagacgat cgtactatga cgtcccatta attcaacgat caatatgata ttttgtagat
    51961 cacccaactc gtttcgttta gcaaagtgga aatggatcac tcgatcattt tcgatttgtt
    52021 cgatgtcttc taaaatagcg ccatccaaat attttcgaag catcatcacg aagttaggcg
    52081 gattatcagg attctgataa tcgatttggg taatctgtac acgagcataa cttgggtgcg
    52141 cagataataa taatcgatgg tttttgccgc gtgaacgaat caccagcacg atttcatttt
    52201 cataaggctg atggattttc gagatccggc cagatagtaa cgtttcacgc aattcgttga
    52261 ccatcgcgtg ggtaaataca ccatcaaagg acatggttca ttcctcattt cttttcataa
    52321 gtatattcat tataacgaaa aaaagaagaa aaaccaattt ggccgaatag taaagcaaaa
    52381 gtctagaaaa atcttggact aattacataa aaaacagtgt ttctatcgtt gaaatccaaa
    52441 tttttaggt
//
LOCUS       DADQCX010000009        50182 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.009, whole genome shotgun sequence.
ACCESSION   DADQCX010000009 DADQCX010000000
VERSION     DADQCX010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.009"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(119..637)
                     /locus_tag="J8R83_000471"
     CDS             complement(119..637)
                     /locus_tag="J8R83_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAZ9573630.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(639..1256)
                     /locus_tag="J8R83_000472"
     CDS             complement(639..1256)
                     /locus_tag="J8R83_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAZ9573631.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1253..2116)
                     /locus_tag="J8R83_000473"
     CDS             complement(1253..2116)
                     /locus_tag="J8R83_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9573632.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(2103..3014)
                     /locus_tag="J8R83_000474"
     CDS             complement(2103..3014)
                     /locus_tag="J8R83_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9573633.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3055..4389)
                     /locus_tag="J8R83_000475"
     CDS             complement(3055..4389)
                     /locus_tag="J8R83_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9573634.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4597..5427
                     /locus_tag="J8R83_000476"
     CDS             4597..5427
                     /locus_tag="J8R83_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAZ9573635.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5671..5920)
                     /locus_tag="J8R83_000477"
                     /pseudo
     CDS             complement(5671..5920)
                     /locus_tag="J8R83_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6111..6305)
                     /locus_tag="J8R83_000478"
     CDS             complement(6111..6305)
                     /locus_tag="J8R83_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573636.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6810..6995)
                     /locus_tag="J8R83_000479"
     CDS             complement(6810..6995)
                     /locus_tag="J8R83_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573637.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7845..8186)
                     /locus_tag="J8R83_000480"
     CDS             complement(7845..8186)
                     /locus_tag="J8R83_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9573638.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8186..8416)
                     /locus_tag="J8R83_000481"
     CDS             complement(8186..8416)
                     /locus_tag="J8R83_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9573639.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8703..9041
                     /locus_tag="J8R83_000482"
     CDS             8703..9041
                     /locus_tag="J8R83_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573640.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9246..9485)
                     /locus_tag="J8R83_000483"
     CDS             complement(9246..9485)
                     /locus_tag="J8R83_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAZ9573641.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9461..9808)
                     /locus_tag="J8R83_000484"
     CDS             complement(9461..9808)
                     /locus_tag="J8R83_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAZ9573642.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10540..11121)
                     /locus_tag="J8R83_000485"
     CDS             complement(10540..11121)
                     /locus_tag="J8R83_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9573643.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11304..11930)
                     /locus_tag="J8R83_000486"
     CDS             complement(11304..11930)
                     /locus_tag="J8R83_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9573644.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11952..13283)
                     /locus_tag="J8R83_000487"
     CDS             complement(11952..13283)
                     /locus_tag="J8R83_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAZ9573645.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13438..13839)
                     /locus_tag="J8R83_000488"
     CDS             complement(13438..13839)
                     /locus_tag="J8R83_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAZ9573646.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13925..14131)
                     /locus_tag="J8R83_000489"
     CDS             complement(13925..14131)
                     /locus_tag="J8R83_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573647.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14226..15728)
                     /locus_tag="J8R83_000490"
     CDS             complement(14226..15728)
                     /locus_tag="J8R83_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAZ9573648.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15746..16201)
                     /gene="argR"
                     /locus_tag="J8R83_000491"
     CDS             complement(15746..16201)
                     /gene="argR"
                     /locus_tag="J8R83_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAZ9573649.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16299..16916)
                     /locus_tag="J8R83_000492"
     CDS             complement(16299..16916)
                     /locus_tag="J8R83_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573650.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17137..18510
                     /locus_tag="J8R83_000493"
     CDS             17137..18510
                     /locus_tag="J8R83_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9573651.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18585..19697
                     /locus_tag="J8R83_000494"
     CDS             18585..19697
                     /locus_tag="J8R83_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAZ9573652.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19769..21406)
                     /locus_tag="J8R83_000495"
     CDS             complement(19769..21406)
                     /locus_tag="J8R83_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAZ9573653.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21574..22182)
                     /locus_tag="J8R83_000496"
     CDS             complement(21574..22182)
                     /locus_tag="J8R83_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9573654.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(22566..23717)
                     /gene="queG"
                     /locus_tag="J8R83_000497"
     CDS             complement(22566..23717)
                     /gene="queG"
                     /locus_tag="J8R83_000497"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAZ9573655.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(23736..24488)
                     /locus_tag="J8R83_000498"
     CDS             complement(23736..24488)
                     /locus_tag="J8R83_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573656.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(24629..25579)
                     /locus_tag="J8R83_000499"
     CDS             complement(24629..25579)
                     /locus_tag="J8R83_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAZ9573657.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(25580..26419)
                     /locus_tag="J8R83_000500"
     CDS             complement(25580..26419)
                     /locus_tag="J8R83_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAZ9573658.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(26416..27162)
                     /locus_tag="J8R83_000501"
     CDS             complement(26416..27162)
                     /locus_tag="J8R83_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573659.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            27400..28770
                     /locus_tag="J8R83_000502"
     CDS             27400..28770
                     /locus_tag="J8R83_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9573660.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(28825..29721)
                     /locus_tag="J8R83_000503"
     CDS             complement(28825..29721)
                     /locus_tag="J8R83_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9573661.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(30002..30679)
                     /locus_tag="J8R83_000504"
     CDS             complement(30002..30679)
                     /locus_tag="J8R83_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAZ9573662.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(30770..31675)
                     /locus_tag="J8R83_000505"
     CDS             complement(30770..31675)
                     /locus_tag="J8R83_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9573663.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            31850..33304
                     /locus_tag="J8R83_000506"
     CDS             31850..33304
                     /locus_tag="J8R83_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9573664.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            33320..34351
                     /locus_tag="J8R83_000507"
     CDS             33320..34351
                     /locus_tag="J8R83_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAZ9573665.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            34358..35545
                     /locus_tag="J8R83_000508"
     CDS             34358..35545
                     /locus_tag="J8R83_000508"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAZ9573666.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            35701..37083
                     /locus_tag="J8R83_000509"
     CDS             35701..37083
                     /locus_tag="J8R83_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAZ9573667.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            37210..37440
                     /locus_tag="J8R83_000510"
     CDS             37210..37440
                     /locus_tag="J8R83_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573668.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(37640..38308)
                     /locus_tag="J8R83_000511"
     CDS             complement(37640..38308)
                     /locus_tag="J8R83_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAZ9573669.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(38497..39294)
                     /locus_tag="J8R83_000512"
                     /pseudo
     CDS             complement(38497..39294)
                     /locus_tag="J8R83_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(39575..40954)
                     /locus_tag="J8R83_000513"
     CDS             complement(39575..40954)
                     /locus_tag="J8R83_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9573670.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(41129..42298)
                     /locus_tag="J8R83_000514"
     CDS             complement(41129..42298)
                     /locus_tag="J8R83_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9573671.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(42273..43424)
                     /locus_tag="J8R83_000515"
     CDS             complement(42273..43424)
                     /locus_tag="J8R83_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAZ9573672.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(43384..44745)
                     /locus_tag="J8R83_000516"
     CDS             complement(43384..44745)
                     /locus_tag="J8R83_000516"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAZ9573673.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(44742..45743)
                     /locus_tag="J8R83_000517"
     CDS             complement(44742..45743)
                     /locus_tag="J8R83_000517"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAZ9573674.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(45759..46454)
                     /gene="dapD"
                     /locus_tag="J8R83_000518"
     CDS             complement(45759..46454)
                     /gene="dapD"
                     /locus_tag="J8R83_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAZ9573675.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(46460..47176)
                     /locus_tag="J8R83_000519"
     CDS             complement(46460..47176)
                     /locus_tag="J8R83_000519"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAZ9573676.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(47173..48054)
                     /locus_tag="J8R83_000520"
     CDS             complement(47173..48054)
                     /locus_tag="J8R83_000520"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAZ9573677.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(48057..48857)
                     /gene="dapF"
                     /locus_tag="J8R83_000521"
     CDS             complement(48057..48857)
                     /gene="dapF"
                     /locus_tag="J8R83_000521"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAZ9573678.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(48844..50103)
                     /gene="lysA"
                     /locus_tag="J8R83_000522"
     CDS             complement(48844..50103)
                     /gene="lysA"
                     /locus_tag="J8R83_000522"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAZ9573679.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
BASE COUNT        14333 a        10388 c         8937 g        16524 t
ORIGIN      
        1 tcatttaaca aaacttaagt tattaagaca aatgaataaa caactacgct ttcctcgaaa
       61 caaaaaaata aagcacaaat gcgcatttac gcactcatgc tttattcgta caattaattc
      121 agataacggc agcgcatagg atgccaataa cacttcctaa aatagctcct cctaaaatgt
      181 cagtaggata atgtaaaagt aaaaaaatcc tcgaataagc gatcaaacaa gcaaataaaa
      241 aggctaatat tcctgcaact ggacttaatt cgaacaacgc agctactgat aaaaaggcta
      301 gcgctgtatg tcctgaagga aaagaagaag tcttcggttt acttgtgtaa aggacaagcc
      361 gacgattttt ttcataaggt cttttccgtc ttgtcgtttt tttgataaaa agcaaaccaa
      421 caaaaaaata gatcaaactg ccgataagaa tggctagacc atattctcta gtatcaggta
      481 tcaagactaa aacagcagca aggagcaacc aaataaaacc accattagag atattactga
      541 taaatttcaa aaaattgatt tttcgactat ccgttttccg ttgcttggcg aacttgttga
      601 taatactatc atcgatttta gcaatcaaac gcaacatgtt attcctcctt tttaagaacc
      661 ttttcttgcg tacgatggat aaaaagcagg acttgaaaat aaaacaagaa actgaaacct
      721 aataaagcaa aatagattgg tcctgcaaac cagaatgcga caagaaggat caacgtgcct
      781 gccaaataga aaagcgcgct tttgaaatca ttaaaaaaca agaaaaatgc agtaatccaa
      841 gaagcttctt tttgttccag ttgaagcaag attttgtaac taaagagaag cgcgcttaat
      901 agaagcaaaa acaacgtagt atacatcaat gtatagccaa ttcccccacc ccaatagcgg
      961 aaaatctgat aatcgatcaa tagaagaaga aaataaacac ttgctaaact atcttgcttt
     1021 ccataaagag agaagttctc acgaaacttt ttccagaata gtgaaccgag ctttttctct
     1081 tcattttttt tgtaatgata aatcatatac agaactgttc gacttgcagt tcctaatgtg
     1141 aaaacaggca agacgcacag gaaccatagt agctgtaaat ggataagacg tggaatccat
     1201 tcaatgattt ctaagaaata atcattggct tttttaccaa tcgatcgatt catcatcctt
     1261 ttgaacctcc tgtcaaatcc atcccttcaa tgaaataacg ttgtgcaaaa aagaacagca
     1321 aaatcgtcgg gatcaagaca agtgttgctc ctgccatcag ataattccat tgtgtcgttg
     1381 cttggttctg aaaaacttgc aagccaatct gtaacgtgta tttttcttga tcttggatat
     1441 ataacagagg acctaagaaa tcattccaag ctgcgttgaa ggaattgatc gcaatggtaa
     1501 tcaaggcagg tttcgtcaat ggaagcatca aatgactcca aatatacaaa tgattcgctc
     1561 cgtcgatttc agcagcttcg atcaattcat tattgatcga taagtaaaat tgacgcatca
     1621 gaaatatatt gaacgcattg ccgaagaacg atggaacgat caggggcaaa taagtaccta
     1681 cccagccgat cttggagaat aatacatatt gagggatcat cgttacaaac cccgggatca
     1741 tcatcgtaga aagaaccaaa gcaaacatca gctttttccc aggaaaatca agcttcgcaa
     1801 atccataagc aataaaagaa tttgaaagga cattaccgat cactactagc acagtgatga
     1861 ataatgtatt tcttgcatag cgccaaaaag gaaaggcggc aatcgtatcc agatagtttt
     1921 cccatacgat tttttctggg aaaaaggtcg gaggataacg aacgatttct tccattggtt
     1981 tcaatgaagt aaacaccatc caaagcaatg gaatgatcaa aatgattcct attactgtca
     2041 tgaggacata acttagtatt tttttgtttg ccgattcaca ctggtctttt tgaaataatc
     2101 catcatttgc cgtcacctcc agaataatag acccacttag gtgcaagctt caaattgaca
     2161 aacgtcagaa ccaacacgat cagaaacagg atcattgaca tagccatcgc ataacccata
     2221 tcaaaagcta cgaacgcctt gttccacata tgcagattat aaaaaagcaa agaatttgca
     2281 ggtccgcctg ttccattttt cgtcatgaca taagcttctt gaaaaatttg gaaagaaccg
     2341 atcgtagagg tgatcacatc gtaaaaaata ataggagtga ttaatggcaa agtaatactt
     2401 ttgaactttc cccaaacgcc tgctccatcg atttctgctg attcatataa agatctagga
     2461 acattttgta atgtagctaa gtaaagtagc attgctcctc cagaactcca tattttcatc
     2521 aaaatcaacg caggtttcgt ccattgtgga tcaaacagcc aagctggtcc agggatatgg
     2581 aaccagccca gaaatgtgtt gatcaatcct gcagatggag aaagcagctg catccataag
     2641 atgtagactg ctactcctga taagactgcc ggtaaataga aagctgtacg gaatacactg
     2701 attcctttga ttttttgatt gagtactgtg gctaaaaaca cactgaaaat cgtcgtcagc
     2761 ggtacattga agatgacgaa ataaacggtg ttgtataacg atttccaaaa taaatcatcg
     2821 tgaacgaaca ttcttttgaa atttgctaga ccaatgaaat tcatcttgga tgtcaaatta
     2881 taatcggtga aactaccaat aactgaaaaa agcataggcc ctagcataaa taccaagaac
     2941 ccgataataa aaggcgagat aaataaatag gcccatcttg cttctttttt ctttcggata
     3001 gataaacgct tcaaattttc ttgcctcctc tgtacctaga cagtcaaaaa tggattattg
     3061 attttgcttg actaagtttt ctactgcttt ttgtgcatct gccaatcctt cttttggtga
     3121 ttttgttcct aaaagaatct ggtcaatctg ttcattcact aatgtcgtgt aatccggagc
     3181 atctaaagga actggtgtga tcaccgtatt tttaaagttt tcgtccgcca tttgatagat
     3241 catttttcct ttatccgtta ggttgtcatt attcactaaa ttctcattgg ctgtcttgct
     3301 cgccatgata tcaaaacttt tttcgccgaa tttttcttgt acttctggag aagaaagata
     3361 tttgatgaat tcataagagg cctcaggatc ttttgctccg tatggtactt ccaagacgaa
     3421 tccgccaccc cacgaccaat ggcctgaacc ttcttctttt tctgggagct gcatcacgcc
     3481 aaaatcaaaa tcatccggtg cattttccat caaactagag taataattga tattttgggc
     3541 acgcatggct actaatccgg aaataaatgg atcagataca ccagacccaa attcggcttc
     3601 taatttattg atcgtatttt tcccataata atcttgccag tcttggatcc actccaaggc
     3661 ttccacttta tttttagtat caatcttgac tttttcatct ttgtcaaacc aactagtccc
     3721 gttatctgcg tttagcgccc atacatcagc ccctaaattc cataatggat aaaaaccgat
     3781 gcgtgtaaat tcttttcctt cttttttatc tagtttacgt gctgtttctt ctaattcatc
     3841 ccaagttgtc ggtagatctt gttcactgat tccagcttct ttaaatatct ttttattata
     3901 aaaaatgact tgtgtatctg tattgaatgg gatcgcataa ggatcacctt catattctac
     3961 tgtatcccaa agctgcggat aaaaatcctt agaagtgtct ttttctacat atttggagag
     4021 attagttgct tgctgtgctt ctgctctttg ggcaacggaa tttatgtcct gtacaataac
     4081 atcgggtgca tttccagctg ttattgcaga taaagattta gtccagatgt caccccatgg
     4141 ctgatactta taatttacat ggatctcgtt ttgtgattga ttgaaatcct caatgatttc
     4201 ttcgatagct tcttttcgtg caccggatcc ccaaaaggac cagaaatcaa tattttttct
     4261 tccatcactt gttttttcag aagaatttgc tgcacttgaa ctggcatcgc ttgcattact
     4321 tgatccgcat cctcctaata aaaacaatgc tgaacttgcc agcaaccctg taaacaataa
     4381 ttttttcata ttttacctcc aaattttaat gtaaccgatg ccggttttaa tataacgata
     4441 tcattttgtt ctgaaaataa caatttataa ggtatgattc taaaaaaatt attaatgata
     4501 ccaatacttt atataattcg cgagcgcttt ctttgaattt tttaatcttt cgtagcagaa
     4561 tgagaatgta ttaaaaatag attaggagga attttgatgt ttagacacca gaaagaattg
     4621 cagtttgaag caaaaccaga tcgtccgaat ccattaatcg cgaaatatct gcaggagctg
     4681 atcggcggcc aatatggcga gatgagtgta gctatgcagt acctgttcca aggctggagc
     4741 tgccgaggag aagaaaaata taaagatatg ctgatggaca ttgcaacaga agaaatcggc
     4801 cacgtggaaa tgttggcgac aatggttgct cgtttattag agggtgcgcc tgttgaagat
     4861 caagaagcag cgatgcaaaa agatccaaca atcggtgcca ttatctctgg aatgaatcca
     4921 cagcacgcga tcgtagctgg cttaggacct cgtcctgctg acagcgtggg caatccatgg
     4981 agcggtgcct atatcattgc gagtggcaac ttgttagcag actttagagc taatttaaat
     5041 gccgaatcac aaggaagact tcaagtagca cgtatttacg aaatgatcga tgatcgtggc
     5101 gtaaaagata tgctgtctgt tctccttgca agagatagct atcatcaaaa tctatgggaa
     5161 tgtgcagtga aagaattaga agaaaaagaa ggttcaatct tagtcccaag tactttcccg
     5221 cgtgacaaag aacgaaaaga cattgcttat gacttctata acttctcaga gggagaccaa
     5281 agtagtgaag gttcttgggc tagtggcaaa gcactggatg gcgaaggcga atatcaatgg
     5341 ttgaaagaac ctaagatcga aggcgctgca ccaaaattag aaccagtaac accaaaaatg
     5401 tatgggacac ctccattcaa gaaataaata tctacccgta gaaacacccg ttttttgttc
     5461 cacacgcttt gtgagcaaaa ctgactaaag tcattaatca taaccaccct tcaaaagggt
     5521 ggttttctct agagctataa gctcaaatca ccggccagcg cctaaagacg ctggctttca
     5581 tattttatgt tcaagccata ttgcctttgc cagttttgcc cacctcttaa aaggtttatg
     5641 tactactcct tagcccttaa aaggatcgtc ttactctcgt acactcagct tatctaacgc
     5701 actatcatgt ttttcttgtt cttgaatgta ctttttgatg gtcgcttcat tttgtcctac
     5761 ttttgtcaca tagtatcctt ccacccaaaa gtgtcgatac ccaaatttat attttagatt
     5821 tgcacaatct cttgatgatc tcctgaatat tggctcgata ttgattataa attatttttc
     5881 ttctatactt tggtgtgaat acaatgtggt atttacacat ctactttgta cgggctaaac
     5941 tatttccctt tattgctcca cccgcatagc aagtggtttt gtatttcaat cgctcggcgc
     6001 gctcaattag gtctaaagac aataaatcta aaaacccgct gcttcactga cagaaacaac
     6061 gggttttcag aaaaaaatga aatgaaaaag atctcttacg gcaatctatt ttattttttt
     6121 gattttttat aaatggaaaa tgcttcaaga agtccaagaa ataaagccgt ataaaaacaa
     6181 gaacctatga aatctttatt tattagatat tcaacagaaa tcccgataac actagccaac
     6241 aatatattta tcagaagtgt aaaataagga tgctttttat agaatagaac tagtgttgtt
     6301 ttcatagact ctcctttctt catatttcca attaatcaca aattcacggc attactagaa
     6361 aaattaaagg ggcgcagaag tggaaaaata ctcttcgact ttccctacaa accaggccat
     6421 cttgtgttta ataactatac caaatctaag gtacctctaa atctaaattc catttgtggc
     6481 ggtgacctcc aatttttaac tcttctatct cccatccagt atacataacc ttgatacttc
     6541 gaccacttat atatcgaaca cacaaatacc tatccattgc aggagtacta cctaacttag
     6601 ttgctacttg catctaaata acagctgaaa agataggact tactcttagt aaagtatctg
     6661 aactattaat ttttaaacta tcatttttat cctcaactac atgcacatct gttgcaactt
     6721 cactttctgt ctcatccaga taaatgatta aggaatcggg aattgcaata tcttcagctg
     6781 acgctggaat agttgagcta aattagtcat catatcttta ttataaaata accaacagca
     6841 aaaaatacaa tgaaaaacaa acttggaact aatgtatcat taataaatgt tgaaaaattc
     6901 agcaactcat tactgtatga ttttagcagc ccaaccaaca tataccctat aaaagctaat
     6961 aagatggtta ggaatccttt agaattttta ctcattcata gacacttcct taaataactt
     7021 ttattataga aggtattgta aataataata ttgacaaaaa gtgactcaaa ataaaaaaaa
     7081 ccttacatta tactggaatg aactgtattg atagtgtacc taaaagctct actgacataa
     7141 gatcgtgtaa tcggtaaagt aattttatta attatacggg atgtaatcaa ttagagaata
     7201 aactaatcat aaaaggtact tttacattca taattgtcgc tttgagattc tactttggtt
     7261 cactatctga cccaattgca cattttcgat cattacaagt attggtgtcg ttagaacaac
     7321 taaataaaaa ctagcggtag atttttcaga atctatgcta atttctgtat ggatgttcca
     7381 gtgatggcaa atttctcttt tcattgtttt tcttgtcgca tgatatgcct ttttgtgtta
     7441 ttcagttaaa ctatagaaat tctttcctag acagatcttg atcccaaatt ttacgttttt
     7501 gagcatcgat atagtttaaa atgacattac tcatatctaa agagtttaga ttttttagga
     7561 ctaaaactgt cagttgttct ttttcttctt tctgttaaag tattgtcgcg acttttcgta
     7621 tacgttaaga tatgtcgtga aaaaacaagt tttgtgacac aaaaaaacga atgacttgag
     7681 gaaatcacct caatcattcg tttaaaatgc tatatattct ttagtttaag atacggaaat
     7741 taatgccatc gaccacacta gtagaatgaa cgacatttac ttggcctttt tttaatttcg
     7801 ttatgtttag catataaaaa tattatagag tttacttaca atgcttaaaa catatactgt
     7861 ataatctgat caattttagc catgtcttgc aatggtaagt tttctatttt tttgagtttt
     7921 cgttccttaa aatcaagaga ttttaattgt gtaataatta cttgtccttt tatatctagc
     7981 tcttcaggta atgagtaacg tgtcggtaaa ttctttatag tggaagtaat tggacatatg
     8041 accgaaaaca ttgttttacg gttaaattca taacgagaga cgactagtcc tggtcgtctt
     8101 ttttgaattt cttttcctac ggagggatca aaatcaatcc atacaatatc acctttttta
     8161 ggaatataaa ttctttcttc tgacactata aaatttctct cccttcagga gttaaatctt
     8221 cccattcgtc tttctcataa tactcggcct cttccccacc actaaatgga tcttcaattt
     8281 ttggaactaa cgtaattgtt ccatcatcag aatacacaac gatatattct tggttttctg
     8341 aaggtttctt tccgttatca gaaggtaaag ttaccactac agaacttcct tgtaatctag
     8401 attttgtaac aagcattatc atcactccct taataaaagt atactatata acactaagta
     8461 acgcaaaatt cccctttgta aactatctag aaaattgttt tgtttaaagt atatcttatt
     8521 ggatataaat agaaataaat tgtagccagt tcattttttc tttaactaaa aaaataatcc
     8581 aagaaacatt gaacctatgg atccaaaagc tacccaaata ctatagctaa ccccccgcta
     8641 ccttcaattt tgcagataaa acgctttggg agaaaatttc aaagacaaca ggccatccta
     8701 tcatgcccga ttataaacaa aaagctggct attccttttg ctctgacaaa tttcaattgg
     8761 gaaagttcac gaaactagca ggtgaagaag tttcaactgt tcggatcaaa gaatgcccgc
     8821 ttcaaataga aacattggtt caacgaattt caactagaca agactttgct attgtagaac
     8881 gtgagatcgt agctattttt gtagaagaag ggattttaca tgatccaact catatcaatg
     8941 tggataaatg gcaacctctt atctataaat tcagagaata tacaactgcc aaccagtcgt
     9001 taactttgaa ttttagattc caagaattca aagagtcata atgataaaca tcgttaggta
     9061 taaataaaaa agactcgcag cacgagtaaa aaacaaatag aagctataca ttagaaaggt
     9121 cgactgtgac cctatagatg cagtatatgc agcttatgag catttcttct gttctctttg
     9181 tttttgggat ctgtgctgaa gtctttttcg ttttttgccg ctctttcttt gaaaaatcga
     9241 ttatgttata ccttctccat tactaattca ggcatctgct gagtaatgat ttttcgcgca
     9301 aaagaaatat ctgttaccca aggttcgatt tgttcttcag tcaagacaag cggcattcgg
     9361 tcatggattg gtgcgactgt gcggttaggt tcagtagtca ttatgattga ttctgccatt
     9421 ttttcatcct gatggctacg ataaaaaccg ccaatataca ctattttttc cttatttgaa
     9481 aacataaatt tgtctttttc ttcattccac tcattgggaa aacacaacga ttttgcaaaa
     9541 atggttgatg aaaggtcttt ttttcttcta ctgtctctgc acgggcatta atcatcaatt
     9601 gtcctttttt aaatccggta aatccccact tcatgatttc cggagtgagg atgttttctt
     9661 cctcttttct taacgtcaca acaagatttg acggaaaaac ttctccagct gctaattctg
     9721 ctgcctgctt cggttgtttc gtctgggctt ctcgataata attctgaagg agctctgact
     9781 ctagatcaaa aaaataacga ccacacatcc taatccctcc caatcttttt ttctatcata
     9841 cactgcaaca agaagttcgc accaacaaaa cgctttcaat ttttgtagaa ctaaaaaagt
     9901 tgtgacaagt gacaaactct ccagtgaatg gtattctcct gccaactcct cggtcacaag
     9961 tcacaatatt caacaaacat gagaagctgc tttttgaaat tgttccttgt gactcggagt
    10021 gaaacggcag gcttacgacc tctgggtaaa cggtgttcaa aagccagttt ctcggtatta
    10081 agccaaattt atgcaaaaat gtagaaagct attttcacaa aatttttctt aatactcgaa
    10141 actaagcgac tttttcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt
    10201 aataagccca accaaacgaa aaatatgagc agctattttt atttggctgt tcttattact
    10261 tgatgcaggg cagctttttc acaacctctc cactaaacgg tgttcaatca gctaaccttc
    10321 ggtattagct caaaaaacgg caaaatatga ggaactattt tgccgtttgt ttctctaata
    10381 ctcaggtcaa agcgctgatt tcacaacctc taatacacgg tgttccagaa gtagcttctt
    10441 cgaaaaataa gccgaaattt cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta
    10501 tttcttgaag ctgaccactt ctgtcacaac ctctaattat taaagaacct tttgcgaagt
    10561 taacaatctt tctttgatca attgaaaatt ctgcctaagt agtgatagat cctgtgtgac
    10621 tttcaacaat aagatacttc cctggatttc agcaatcaac gctttggctt gacggtctgc
    10681 ttcttcatcg gacagttttt cttcagaaag tgccaggata ttttgtttcg tatacttgac
    10741 ccattgattg actaattcta gtagcaacag acggtattct tcatccactg tactcaactc
    10801 aataatcaaa ttacctacag gacagccatg ataagtgatc tgtgtctcat gatcagcgaa
    10861 aatccagtcc aacatttctt ctaatgcttc ttctggctgt tttccagcat ttaagatgtc
    10921 ttcgaacaat tctgtctgcc atacgtccat atgcgcatgg atcaccgcta gacaaacttc
    10981 tttttttgaa gaaaagtaat aataaaattg accttttcct gtatcagaag ctgctagaat
    11041 atctcggatt gacgtttcat gatagccttt tttataaata agatctttgg tcgcttccaa
    11101 gatcttttcc tttgttttca atgatattct cctttttcat ttctcatagt cctatattat
    11161 acagtaaatt catcattttt tcttcttaat cgtttaaaaa agactgtgcc aaattatctg
    11221 acacagccct cactataaaa ctgttctcat atagctagat gttcattgat tcaagaactg
    11281 cgaggacaaa agcaattcct atcttatgat agttgctcta atacttcctc tgttgtcatc
    11341 acttgatctg caataaagcc aaagttcgtc aacgctgcat ccattgcttc ttggccagga
    11401 gcaccaattg catctgtcgc taccacaaca ttgaatccac tctctaccaa ttcacgcata
    11461 tgggaatcgc tacacaagtt tccgttcatt ccaccaagaa ttactgtgtc gattccattt
    11521 tttctcaatt ggagcgccaa atcattgctt tctggtccaa agattttatg aggagagctg
    11581 atgatcgtat tttcatccaa ataaggtttc aattcttcga taaaatcggc tcctgaacct
    11641 tcttccactg attcatattg actttttcta gcaaacatct gctgctcaag catcatatgt
    11701 tctcctgcac cgccaaattg ccatttatgg tcatgtgggt aaaaataatg aggagaaata
    11761 aagagtttgt atcctttttc ttttgcttgt tttaccattt caatcatatt ttcgatcgta
    11821 ttgtattttt ctaagatatc ttttgtcaaa ccaaagccac cgcctgctgg tttcaagaac
    11881 tcgacttgcg ggtcagtgag aactactgct gtatttttat tattgaacat ggtggattct
    11941 ccattcgtta tttattttaa tacatcattt agagcttcac tcattgtcgg atgagaatag
    12001 atttgatctc tcaataacgt ataaggaagt tttccattca tagctagcga aatcaagttg
    12061 atgacttcat gagaatcttc cgcatagata cttgccccta gaatcaagtc agtttcaggg
    12121 tcgactaaaa ctttgaatac acctttagga tcttctaata cttgtgcttt agggacaccg
    12181 cttgtcatat acttgaataa tttgtaattg acgccttgtg ctttggcttg tttttctgtt
    12241 aaacctacat tggataaagt cggagtgata aatacactgt aaggcacagc tttccggtta
    12301 ttcgttgttc gtttattctc gcccttcaac tgatccataa tgattcgata atcatctaga
    12361 gagatataag tgaactgcaa tccgcctttg acgtctccaa tcgcccaaat gttgtctgca
    12421 tctgtacgaa ggtattcatc cacagcgatt gctccgcgat ctgttagttt aacatctgta
    12481 ttttctaatc caagtgatgc tgtacttggt tttcttccag ttgcagccaa aacttttgac
    12541 gcttggattg ttacttcttg gccatcttct gtaaaggtga cggcagctgt tgattcttgg
    12601 tctgctactt gatctacaga tacacctaga tggaattcga ttcccgcatt tgtcatgtct
    12661 tctaaaatca tttgcgcgat atcttcatct tcacgtggaa gaaattcaga atgggcatca
    12721 agaacgacaa ctttagatcc gtattcattg aacattgatg caaattccaa gccaatatat
    12781 ccagccccga tgatcactaa tttttccggt aattgttcct gatccatcgc ttgcgtagaa
    12841 tcaatcaagt agcgacttgt attcaatcct ttgattggta aaatgattgg ttcagaacca
    12901 gtattgatga aaatccgttc gccttcaaca atcacttttt caccattatt cgtcacttcg
    12961 atttgatggt tagaaagaaa acgtgctgta ccgtccatca ctgtcccagt tgcctcatcg
    13021 ctgatcatat gataattttt ggcgcgaagc atgcccgtca atttttcttt ccgagcaaca
    13081 gcctctgtaa agtcgattcc tctttctcca ttgaaaatca atgatttaga aggaatacag
    13141 ccgatgttga tacatgttcc gccatacata cgtgttgact tttcaacgac taaaaccgat
    13201 tcaccttttg aagctaacgc cttcgctaaa gtcttaccgc cctttccaaa accgatcaca
    13261 atattttgat atttttccat catttttccc tcgcttcttt tttacctacc gattggtaca
    13321 aaaatatgat aaccgataat tgtctattct ccaaatcatc tgctttattt gtcaaaaaaa
    13381 accagacaaa aagcggtcct ttcacgtttt tagtctggtt cgatttcctt tattcttcta
    13441 aacaatcgtt acttctacat cgatatttcc tctagttgct ttggagtaag ggcagaattc
    13501 atgcgcatct tctgcaattt tttgggcttc ttcttcgctg atgccatcga tatgcacttc
    13561 taatactaca ccgatctgat agccgccatc atctaaatta taaagagaga cacgtgcttt
    13621 tactgtggac tctgctgtca ttcctgcttc tttgatcata tgttgtaccg ccccattgaa
    13681 acaagaagca taacctgctg caaataattg ttctggattt gttccttctg catggattcc
    13741 tggaggagtg attttcatat gcatcgagcc atttggtgcc tcgacttctc cattgcgccc
    13801 gccatggttg atcattgctg tttcgtatgc ttttttcatt gtactgctcc tttcgattga
    13861 ccatttgcta cttggctata attatagtgt atgacaagta aggcgctttc tacaaaaatt
    13921 ctgcttattc gaataccaga atgccgtctt ctactatttt tccaaaaaac aaaaaaatac
    13981 tactcgtgaa caacagcgtc atatttgttc caaaataaat agcaatcttt tctacataat
    14041 cttttatatg attgatttta agatacatat ataccagaaa gttgacccca taaaccaata
    14101 ctgttaaaaa aataaccata ttcgttacca ttttttcctc cttttgctgg tctccctacc
    14161 agcactcgat ttaaccatac cacttttttt gccgtccaag caactagcct ttcaaaaaga
    14221 ctggtttatt ctgctgttaa tgattcaaga tcagaaaaat gtccgaataa ttttgctaat
    14281 tttactaacg ccaacttgtt ctttccgaat tcatcatttt ctatctgtaa tactagtaac
    14341 ggctcatgta agcttaaacg gatcaaaaac cagccgtttc cgtatggctc ttctagatca
    14401 tatcgaatac cttcttcatt ttccgggtcg aagttcatcc ctttttcttc ttccaacagt
    14461 cgcttcattt cttctaatat cttgtttcct tgttcgcgtg gttcatcgct gaacaatttt
    14521 aatcggattt cttgtacttc tacgggctgt ttcaactctt tgatttgttc atctaatgtg
    14581 ataccttttc tttttaattc tggcaaaagc atcaggatct ttgcgatgac atatgcacca
    14641 tcatccagaa aatagttttc cttgaatgca gcgtgtccgc ttgtttcgat ggctagctgt
    14701 gtatctttcc caagacggtt aagttctaat gctttattga ttacatttcg atagccggaa
    14761 atataacgaa cttggatgcc tcctttttct tcaatgaatc tttgtagatg agaagaagta
    14821 ggggaattcg tcacgattct tgttcctgga tgctctttta atacgattgt acttaatact
    14881 gcgatcaaat tatttcgatt gatcactgtt ccagaagcac tgacaactgc agaacgatcc
    14941 acatctgtat cgaaaatgat cccaagatct gcttcatttg ctaaaacagc ctgcttgata
    15001 ctttccatcg cttctttatt atcaggattt gggatatgat taggaaatcg gccatctggt
    15061 tccaaaaatt gggaacctgt tgaatccgca cctaagctat tcaatacttt ttcagcaaag
    15121 aatccaccag caccatttcc ggcatcaaca atgattttcc aaccatttag tggtttgctt
    15181 tctagtgttc caatcccctt tttaattttt gtgactaaat cttgcgcata aggtgtcaaa
    15241 aggtctgctt tttctacgct tccagtttgt tcgcttttta ttttttgctg ctgtgatagg
    15301 ataaaagcaa tatcttcttt ttctgctcct ccttctgagg taaagaattt tattccatta
    15361 taataatagg gaagatggct agcagtcagc ataaccgcag catcgcacga gaactgttca
    15421 aattgagtgg acataaacat agcaggcgta gtagctaatt cgaaatcgat gacatgtatc
    15481 ccttgttctt tcagactttg gatcaacgcc tctttcagtg ctggtccgct tatcctactg
    15541 tcatgaccaa tcccaatcgt ccatttttta tttggatcgg ttgatttctt ctttttcttt
    15601 atccagtttg ctagtcccca gccgatcttt tttaccatgt ctgtcgtcaa gtttacttca
    15661 tatccttcaa ctggtaatgc gattcctcga atatccgatc cattttgcag cgctttcata
    15721 tctttcatat aaaagtcctc ctcatttatt ccctcatttt ttccagcttt tctgcaaatc
    15781 gctgtgcttc ttcttctgag cggcaaataa taatgaatgt atctacaccg gccatcgttc
    15841 cgacaacttc agggtaagcc acttcatcta gccaattcgt taccacatcg gcaccatttc
    15901 gttcagtcaa tacgataacc atgaactgaa cagactggat acgcaaaacc tcgcgtctaa
    15961 ttgctgtacg caaacgttct tcatttaaag aaacagatgg ctggttaaat aatgtatagc
    16021 gtactatttt gttttcattt tgacttttta ctaacttcat ttctcgaatg tctcgagaaa
    16081 tcgttgcttg agtcacatcg gcgcctgctt catgcagccg cgcaagcagc tcttcctgtg
    16141 tcccaatagg ttgttctgta atgatctggc ggatcagtgc ttgtcgctgt ttctttttca
    16201 tattagacac ctctcaatgt tgattatagc aaaagataag taatatttct tcatattttg
    16261 gtatttttta cttttatttt ttgttttcat tcaggttgct aacctttttc tattttaaca
    16321 cgcaaaatcg tcttcatttt ttcaggtgct gattttcttg gatcgctgat gtaaatctct
    16381 ttgtgttctt tagaagctct ttcatagcct tcttttgcga tgaatgcttc taatttctca
    16441 aacgttgctg gttcttcggc atagggcccg acgtgtaaga tttgggcaca aagaccttct
    16501 tccatctttt tgaatactac ttgttctttc aagtcttccg gaagtttgct agaacgctga
    16561 atggcttctt gtgctatcgc ttctgtaaca aagtcaggct gtcggatcat caattgataa
    16621 gaaaaatgtt cttttttcat cactggttca tgcaaatact tttcttgcag tccccattgt
    16681 ccttccagtg gatagacagt atacatctga taatcaggaa tcagccaatt ttttttaggc
    16741 gacatgcgta ttgcatagct gactgcatat agacaggcta ctcttcgttt aaagtcttcc
    16801 tgattcgggt cgccgatccc tctgatgcta aagaatgatt ttttaggaac ctctagtatt
    16861 tgcgggcttt ttttcatact atagctcttg tctttacgcc attcaatttt ttccattttt
    16921 cttcctccgc gaaattccat ttagttattt attatcatac ctctttttga gtgacttggc
    16981 taatcgtgtt gacactattt ttcagtttgt gctagaataa gtgaagtaaa taaatcgtac
    17041 agataacacg tttcggcgtg tcgagagaga ggcggtttct atttttataa tagaaatcac
    17101 tctctttttt tacgaaattt tttagaggtg atgtaaatga caaaacaaaa acagctgctt
    17161 ttagtacctg cagtaattgc aacagggatg atgtcttttg cgggcgtatt gatcgagacg
    17221 gccatgaatg taactttccc aactcttatc agacagtttg atttaacgac tgcacaagtc
    17281 caatgggtaa caacgattta tcttttgatg atttcgatca ttgttccgct gtctacttat
    17341 ttgaatcgca attttagtct caaaaaactc tttttagctt caaatctgct tttcttggca
    17401 ggtataatga tcgatttctt ctctcctacc ttcatggtcc tattgtttgg tcgattgctc
    17461 caaggtgcag cgacaggtat cgctcttccg ttgatgttcc atattatctt gacatttgcc
    17521 cccctcaatc gacgaggcgc gatgatgggt gtcggtactt tgacaacggc cattgctcca
    17581 gcaattggcc ccacttatgg aggcattatg acttcacatt ttacatggaa tcatatcttc
    17641 ctgtttcttg tgcccgtttt gtttctttct ttgattatcg gctggtttgc tattcccgag
    17701 atggcagtac aaaaaagtgg ttatttggat tggataagcg ttttaggaat ttgtcttttg
    17761 tttagtggaa gtctaacatt tttgagtacg ttgggaacag tttccagctg gattgcttta
    17821 atcatcggcg gtattggctg gttccttttt tactatcgaa gtaaaaaagt ggagcatcca
    17881 ctgatccgac tgtctattct ttcaaataaa acattccgct tgtttttgat tggcttctta
    17941 gtttatcagt ttttattact tggtgtatct tttgtcttgc cgaatttcct tcagatcgtt
    18001 caaggaagta gtccttttgt cgctggatta gcgatgcttc ccggcgcagc ggttggtgct
    18061 ttgctttctc ctttttccgg gaaaatgctg gatcaatatg gtccgaagaa gccaattttt
    18121 gctgggctga ttctttcttt gattggttgg ctagcattat tcctactcat aggacacgct
    18181 tcagtgggtg tattgattgc ttgtcatgtg ttttatatga tcggtatcgg attatcttac
    18241 agcaatatga tgaccaccgg aatgaatgca ctgaatgaag aactacaagg agacgggaac
    18301 gcaatgttca ataccttgca gcagttttct ggcgctgtgg ctacttcatt agtagcggtc
    18361 attatcaatt acgtccagca tcatacttcc cataactatg aagtgtctac tacattagga
    18421 tcaaaagcag cattaggcgt cttgttgctg ttgcttctcg taagctttgc tcgattcgcc
    18481 tattatctgt tctttgctaa aaaagcgtag attccatata cggcaggtgt tgcatctgcc
    18541 gtttttttgt gtgaaaatgg ttgtttgtaa aaggaggctt ttttatggaa aaaattgcca
    18601 ttatcggtgg cgggatcatt ggtatgaccc tagccagtta cttagataca tcaaaattca
    18661 atgttgcttt atttgatgaa gggacaggac aggcaactaa agctagcgct gggattatct
    18721 ccccttggtt gtcgaaacgc agaaacaaac aatggtatcg tctggctaaa gacggcgctg
    18781 cttttttccc taaacttata aaagatttcc aacttgatca aacgatttac gcacaatcag
    18841 ggacactttt gcttcgacct gaaaaagatt tagctgaatt ggctgttctt gccgagaaac
    18901 gaaaagaaga agcgccagaa attggaaaca tcgaatggct ttcacctgaa cagacatctc
    18961 aagcacttcc gttattgaaa ccagcagttt cactgcgtat cagtggtggt ggtcgtctgg
    19021 atggaaaagc atatttagaa catcttggtc agcgtttagc acaaaaacaa atggagcaga
    19081 tccaggcaaa agtcactttg cataagaaga gcgattcttg gctcatcaag ggaccgtttg
    19141 gagaatacac agctgatcgt gtaattttga cacctggccc ggcacttaag cctttattac
    19201 aagaattagg ctatgctgca gatatacgtc cgcaaaaagg gcagctctta gcatttcaga
    19261 catcttataa gatgagtcaa gactggcctg ttgctatgct tgacggagaa gctgatttca
    19321 ttcctttcat ggatggaaag atccttttag gtgctaccca tgaaaacgat caaggctggg
    19381 atttggctcc tactagcgaa gcttataagg gattgactaa gagtacagaa cagttcttga
    19441 ctgatccaga tcagataaaa aactggccat acgagttccg tgtaggtacc cgtgcttata
    19501 cgtcagattt ttccccattt ttcggcgtac tgccagatga tccaagctta ctggctgcta
    19561 gcggtctagg ctcttctggc ttgaccacag gtccttatat cggctatcta ttagccaact
    19621 tcttaaatac tggtcattgg cctacggaag attatcaaaa ggacatctcc acctatatta
    19681 cgaaaaatcc atcatagaaa aacagctttt tcaagtaagg atcccgagcg atattgcgca
    19741 tggattactt cttgaaaaag ctgttatttt agttcaattt ctgaatcaaa ttctccaaac
    19801 tttcttttgc ttcatctggc aagagatctt ttcctatctg agcttcaatg aatcgtaaac
    19861 gaatatcaag tcgttgtttc accagatttt tataggacgt atcctcaaaa gaaacaggaa
    19921 aatctggtat aggtaaatag tggatgtctt caaatggacc aaacgacttg aattctgccg
    19981 tttgttgcac gattctttca acgattgaca atgtcgtttc aggtttgatt tttttatcat
    20041 cgaaatatcc agtattcagg acatagcagg ctgtttgctg tttcaaaaac aactctcgaa
    20101 aagcttgata gtcttcccta agaggataga cacggaaagg attagcaaat ggttcaatga
    20161 ctagctcatc tagctgtctt tttgtagtga tattttccgc gtctgatcgt tttgttgcta
    20221 atgttgcacc aaaagacgct gctaaaactg ggtcattgat cttgataatt ggcggaagcg
    20281 aatcatcttt catgatccaa aaaacagcat cgatcttttc gctaagatga tcgactcggt
    20341 cgggtgtcgc ataacgtgat ttgactgtcc gcccatttcc gtttcgtata tctcctgtta
    20401 ctaggacttt ttctccttta cttgtacatg tcacgcccac attctgacaa gtaaggaaag
    20461 aagaaatggc cggatcatca gacggatagt cttgtgtttt atcaaagtaa gaaggttcca
    20521 aggcagtagc aaaaccattt tttcgagaaa taacgaaagc atcgtcatgc aagatcgaaa
    20581 cagagtgacc ttccgtatgt tttgctaagg taatcgttga ttttccagaa ccggacaacc
    20641 caaatacagc catcgtatag gtctggtcat tactagcata ttgtttcatc ccaccgtggc
    20701 aggcaataaa gccattgcga tttcccaatg cccaagcaag cgtcaaagtc gcttttttta
    20761 attctccaaa gtaacgtaat cctagcacag ccgctgtatt atggagagca tcaaacaaaa
    20821 tgagtccatt tggaaatgtt tcatgtgtcc attcgggatc acaaaagata taaagatctc
    20881 cctcatcaaa ggaaacagac ttttgataag tctctaagat cttcgaattc gctggctgaa
    20941 aattcagcaa ataagaatac aaattgttct caaatccttc tggaatcagc aaatgacttt
    21001 gcacagaaaa ttcttcagat aggccaacga ttacttttgt atggtaaaac tggcgcttgc
    21061 gactttgata cacagcttct cttaaaattt tctcgtattt gctttgttcc ttgtctaagt
    21121 cctcaaagat ccgccgagca cttgctgttc ttcccacaat gcttccatca ttgaatacta
    21181 gtgtcctaac atcagctggt aaatctagtt cttcagcatg tgagattgtt aaatctgtga
    21241 tgatcgttcc tggactccct tttgctagtt gataagctgt cttcctatca aaaacttcat
    21301 gaacattatt accgtaaaat gtcgtttcta caatcgatcg aatactggat aacagtggat
    21361 ttccacttgt gatttcgttt aattcgagac tctcttttgt actcatggct cctcctcatt
    21421 ccctaaacaa aaaaacgttt tctttattat acattattcg agtttttatt tgtactgctg
    21481 cgctgtggga agcaaacgag ttatttttca cacaaaaaaa ccgagaactt gaataaacaa
    21541 gtttctcggt ttcatcattt tccttttatc ggcttagtac cagccgtttg ctaaccagaa
    21601 tgttttagca gcatcccatg aaccataacg agatgttaca tattgttctg ctacacgttc
    21661 ttgattggca gctgaatagt cgccgtttaa gtatgaagca tctaattgat aacggccgat
    21721 gtaacgtccg ttagtagctg tgtatgaacc gcctgattct ttttgtgcga tccattcttt
    21781 tgcagagctt gaagttggcg ctgttgcagc agctggggca gcaggagcta cttcaactgt
    21841 ttcaacaggt gcaacgtatg tatgttcttg cgttgctgtt tcagttgtag atgctgtatt
    21901 ttctgttgtt ttgttttctg ttgttgctga agaatcattt gaagttggga ttgttaattg
    21961 ttcaccaaca taaatgcggt tgatgtttgc gatcgaattt ttttcagcaa ttgcatcgat
    22021 cattgagttg tctcctgcaa atttttgtga gatcttagat aatgaatcac ctgattttac
    22081 tgtataaact tcatcagcgt gagcatttgt agttcctaca aacattgcag tagcaccagc
    22141 agcaaaagtt gtacctaaaa caattttctt aaatgaattc atattaaact cctttttttc
    22201 tccgtttttt attctttcga cgctattaac tttatcattt agaaatattt cataggtaaa
    22261 agaaacatga catttaatga caaaataacg aattatttaa tatttgtaac atttaaacaa
    22321 atattttttt gatacaaaac cataaaagcc ttgttgtata agcaaagtaa tcgtttttct
    22381 atgttttttt atttttgaat gaaaaacgca gattctgtaa cattcactgc aataatccat
    22441 aaaaaaaagc aaaaaaattt ttgattttta tcaaattctc ttaaaaaaat gtaaaaaata
    22501 caaaaaaacc agtaattgtt acaacaatta ctggacaaaa actttgaata atgttaacta
    22561 tttttttatt ttaactttct ccgcaataat ttctgggcat gttccaattc gtttataacg
    22621 acttcttctg tttctttagc taatatttca tctaatacat caagccattt ttccggttct
    22681 tttgttccta gacgtccaat agcccaagct gctgttcctc tgatgacagg gcggacatct
    22741 gttaaacatt ctgaaatctc aggcaatgcc gttcgatcac ctagattagc taaagcaatc
    22801 aatgcgtttc tctgcaaagg tttcttccca cgccatgaac cagctaaatg cccaaattgc
    22861 tgtttgaagt ctttattaga catcgaaagc attggcttta attttggata tatttcgtct
    22921 acttttggtt ccatctcttc atgaaaatga aaatcttttc cttgattgta agggcagact
    22981 aactggcaga tatcacatcc ataaatgaca tttcgcattt ttttacgata ttcttccggc
    23041 atcatccctt ttgtctgagt ttgataagac aaacatcgct gggcattcat tcttccgtca
    23101 ccaagcaatg cttttgtcgg acaagcagtc acgcagcgca tacagtcacc gcaaccaaat
    23161 tctcctggtt tatcaggctc aaatacaata ttagtaacga tctcaccaag atagacaaat
    23221 gaaccgaact cttcagtgat caacaatccg tttcgtccaa taaatcctaa accagctcgc
    23281 tgtgctacag cgacatcgat cagttctcca gtatctactt gcggagctag acgccattcc
    23341 tcttcttttt gccatttttc tgctcttgtt tggatgaatt cgatcaatcg gttcaaacgg
    23401 tctctgagta tatcatggta atcgatcccc caagaagcac gagcaaactg cccgcgtttt
    23461 tcatccctag gcacttcttc atggatccta gtaggatacg caagtgcaat ggaaatgatc
    23521 gatttcggct gatcaaatgt catttctgga taaagacgct catcgatatt tggatgttca
    23581 aagccagaag tatggccagc tgctttttgt tcttccaacg attcttttaa tgaatcaaaa
    23641 ggttccgccg tggtgaaccc gattttgtca attcctaatc gtttgctttc ttgtatgatt
    23701 tcttctttta atgtcatggt cttcctcgct tgctgttaac ggctgtataa cccataatat
    23761 agtttttctt ttttcagctg gacaaactgg atctgctgat cggcaatctt cttttcttcc
    23821 atccattttt ttcttgcagc aaatacttcc caataatttg ttgaaattaa ttttcttttg
    23881 ttatctaatg cattaaaaaa attcaatgaa actggttttg tacttaacag ttcatggagc
    23941 cttacctctt cccatggcga aaactcagac agatcgcggg aatacaatac ttcttcatag
    24001 agattttttt gctgtgtgta cgtgaatgtt tgcgggattt tcccaggcct agcaatttct
    24061 actagacgat tataaaacat attcattaat ttgctgttgg caataaattg acttttataa
    24121 taggccgact ggatcttttt gattactcct tctgctttga tgactgaaaa taatgcaggc
    24181 catgctttga cggttatttc gtcgttttgt ttaactaata cgccaggtgt gaagccgact
    24241 ggagaaagga acacaaaata accgataccg gtattttcat ctaaaggctg aaattcatca
    24301 aacaaccatt tgcctatgta cagctcttca tctggttctg ttgtctcatt ttgatttgct
    24361 atgaataatt tagctaattc tgcttcaaga aattgaaggt cttgatcctt gtcggtattt
    24421 tcctgctggc tgatcaatcg aaagacttct tctttaatcg tatatttatc tttacgtgta
    24481 aaattcatag ccacaccttc cttccttact ctaactataa cggaatttct tcaaaaaagg
    24541 tatctgtacg acgaaaaaca gcataatttt ttttcatatc tcttataaaa aatgcaaggt
    24601 ctgctcctca agctagacct tgcacttttc agctttcttt tgtttgtgac aaaccttcat
    24661 ggatcgtttc aatattccat ttcatcatct gatagtaaga atctccttgt tctccttctt
    24721 ttgctatgga atcagtgaac agtttatcat agattttcaa acccgtttct tttgctaccc
    24781 gttccatgct tcttgagtct acactggttt ccacgaataa aaccggtact tcttttgctc
    24841 ttatctgatc aatgatcgct ttcatttgat caggcgtacc ttgactttct gtattgatct
    24901 cccatatata agctgctggc aaatcatatg ctcgtgaaaa atacttgaat gccccttcac
    24961 ttgttactaa taattttttg ttctcttcga tagaagcaaa actttccttc gcttgtgtat
    25021 ctaattcttt tagtttttcc acatatgctt ctgcattttt tttatagagt gtcgcatttt
    25081 ctgcatcttt ttcagagaat atacgtgcga tttcctccac atattttatt ccgttagata
    25141 ggtctagcca agcatgggga tctgcttttg tatgttcttc accgctagtt aaataaagag
    25201 gttctacatt tttgctaact gcaaaataat cttttccttc ttctttttta gccgtttcca
    25261 tcaagttatc gaaccagctg ttacctgttt caagattcaa accgttgtat aaaataacat
    25321 ctgcatcgct tgcctttttg atgtcttctg gtagtacttc atattcatgc ggatctgttc
    25381 cgactggtac gatactgtgg atatctattt gatctgttcc gacctctttt gccatgtccg
    25441 ccaagatcga attggtagcc acgactgaca acttttcttt acttccttca tccgcttggt
    25501 cagaagcctg ctttccgcaa ccggctaata ccaagaaact aactgccaag attaaaaaga
    25561 gtgatttttt tgttttcatc tatctgcttc ctttctgaaa taaaattcct tttgttggag
    25621 aaaataaaaa agcaaggata aaaaatgcgg tacatgctaa cacgatcgta gctcctgatg
    25681 gccaattgta actataactg aaaaacacac cgacaactgc acttagcata ccgattcctg
    25741 cagctgtaat gatcattttc agtaaatggt tcgttagcaa gtaagccgtg gcggctggtg
    25801 tgatcaacat ggcaatcacc aagattgttc ctactgtctg taaactgact acagccacta
    25861 atgtcaaaaa gaacatcaaa agataatgga tcagcgatgt gttcagccca taagcttttg
    25921 ccattgtcgg atcgaatgat gtgatcttca attctttata aaagaaaaag acaaatatca
    25981 agacgattcc actaacgagt gctgtcagca acaaatcgct ttccctaaca gctaagacat
    26041 tcccaaataa aatatgatac aaatctgtcg cactctgggc atatgaaatc aagataatcc
    26101 ctaatgcaaa aaaggagcta aagacaattc caatcgctgt atcatttttc aatcggctcc
    26161 gctgagtcac gaaaccaatc actgctgctg ttagcatccc aaaagcagtg gctccaaaga
    26221 tgtaactaaa accaaacata taagaaatgg ctacacctgg aagaactgcg tgagagatag
    26281 cgtctcccat caaagacatc cctcgtaaaa taataaaaga accgatgact ccagaagcaa
    26341 gtcctacaag catggaagtg accaaagcgt attgcaggaa ttgataattc attaatccat
    26401 caataaagga ttggatcatt ttttctctcc tccttttact aaatgtctga tgatctcacc
    26461 ataggccaat tgaaggttct tcgatgtaaa gacttcttgt actggaccgg aagcgatcag
    26521 ctgtttattt aaaagaataa cctcatcgaa atattcttct actttatgaa gatcatgatg
    26581 gacgatcaaa atcgtttttc ctgaattctt caattcctgc aagatgtcaa agatctttcg
    26641 ttcacttaac gcatcaatcc ctacgaatgg ttcatctaaa aagatccatt ctgctccttg
    26701 ggctagagct cttgcaataa aaactctctg aagctgtcca cccgatagtt cgctgatctg
    26761 tcttttggca tattcttcca tccctacttt tttcaaagct tgtcttgcac gttctttttc
    26821 ttttttccca ggtctttgtc caattcgtaa agatggatat gttcctaaaa gtacaacgcc
    26881 taatacatca attggaaagg aaagatccaa ttcacttcgc tgttccacgt aggctatttt
    26941 tttacggact gagtttaccg actgtccaga aaaggtgact ttaccagtag tagctggtat
    27001 caactctagc aaagatttca taaatgttga ttttcctgca ccgtttggtc cgataatacc
    27061 ggtaattttt tgtggattta tcgtcaagtt gatagttttc aaaacagttt tcccttgata
    27121 agcggctgaa aggtcttgaa ttacaatggc cgtacgttcc aaatcttaca ctccttttta
    27181 ggtttaccta actttttatt taaatatagt ttaactaaaa tggaaagcat tttcaagtag
    27241 aatgatgaaa aagttttttt cgaattttcc tcgcatttta tgaaaatttt ctgtagaatc
    27301 acatcaagag ttcaataagg ctaacctaat aatgaaaaac atgtgttgaa acgtttgatt
    27361 attttttctt gttgactcaa caacgaaagg agtttttgta tggaagaaga aaagttaact
    27421 cgaagtctta gtgcccgtca tatccaaatg atcgcactag gtggaacgat cggtgtcggt
    27481 ctgtttatgg gtgcctcctc aaccatacgt tggacagggc cctcagtgat gggagcctat
    27541 gcgattgcag gattcttttt gtatttgatt atgcgtgctt taggcgaaat gctttacgtt
    27601 gatccttcga ctggttcttt tgcaaattac gcgagcgagt acatccatcc tgtggctggc
    27661 tacttgaccg cttggagtaa tatttttcaa tatattgtcg taggaataag tgaagtgatt
    27721 gctgtaggat cttatatgaa ttattggtgg cctgatttgc cggcaattat tcccggaatc
    27781 attgtcgtct tgtttcttat gctggcaaat cttatttctg tcaaggcgtt tggcgaatta
    27841 gaattttggt tttcgatcat caaagtcata acgatcattt tgatgatcat tgcaggtctt
    27901 ggggtaatct tatttggatt tggtaatcat ggtcaggcag tagggatttc aaatctttgg
    27961 aaaaatggtg gattcttcac tggaggcgtc aaaggatttt tctttgcatt atcgatcgtt
    28021 gttgcttcct atcaaggaat cgaactgatc ggaatgactg ctggtgaagc agagaatcct
    28081 aaaaagacga tcattgaagc tgtccagtcc actatcggtc gaatcttgat tttttatatt
    28141 ggtgctattt ttatcattgt gagtatctat ccgtggaatc aattgagtga gattggttca
    28201 ccttttgtac aaactttttc taaagtcggc attacatttg ctgcaggact gattaatttt
    28261 gtcgtgatta cagcggcatt atcaggttgc aattcaggga ttttcagcgc aagtcgtatg
    28321 gtctatacac ttgccataaa tggaaagatg tctaaaaaat ttctgaaact atctcgtcac
    28381 ggtgcgcctt tttatcctgt cgtagcaatc tcaggtggaa tcttaattgg tctgatctta
    28441 aattatcttc taccaatgtt catcaaccag tcagaaaata ttttcgtttt cgtatacagc
    28501 tcaagtattt tgcctggtat ggttccttgg gtagtgattt tgatcagcga gattcgcttc
    28561 aaaaagaagc acgcagataa aatgcatgat catcctttta aaatgccact atctccttat
    28621 acgaattatg tgacacttgc ttttttagct atcgtattga ttttcatgtt tatcaatcct
    28681 gaaacgagaa tctcattgat tattggactc gttttcttgc tttacatgac gatccattac
    28741 tttgtacgcg aaaaaagaac cggaaaataa aaaaagaacg aagcttcacc ttagtggaag
    28801 cttcgttctt ttttattgct tttatcaatt caattttagc gtctcaccgg gagtcaggaa
    28861 ataattctcc atgctcatcc cattcagcga caagatcgtt tctactggta cgccagttcg
    28921 ttcggctatt tgatttggac cttctccttc caaaactacg gttgtcgcag cctgtgaagt
    28981 cgcgctgttg gtattagttt cagaggaatc tgttgtgtct tgtgttgttc gagcttgcat
    29041 ttcagaagct tctaccgact ctgctgtctc agaatcagaa gatgttgtgt cttgtgtgct
    29101 tgttgactct gcttgaagag aggcgctagt ctgcaaataa atatcggaaa tcttagcgac
    29161 atgattcgta taattagccg ataattgatt gatcaaagta tctaagtcta caccgtcttt
    29221 attttctgct gcctgatacg ctgcacgtaa ttttctgatc ccttcgtcgg agattgcttg
    29281 aagctcacgt gctttttggt tagcaactgc tgataaacca gctattccct cttgatttcc
    29341 ctgaatttct gtctggtatt cttcaatcaa tgcaggcgtc ttttcttcga tctttttcga
    29401 ataatcattt acgattgctt gaagttgctc tggcaaacca tttgctgttt tttcttcaga
    29461 agtttgtgtc tcttttgttt tagttgatga ctcacttgtt tgtttcgtct ctgttttctt
    29521 tgtcgttgtt tccgttatgg tcgtactttt cgcttctgac gaattttttc catgaaaata
    29581 tagacccgca actcctcctg ctatgatcaa aaacacggca actgctgccc caatcatgat
    29641 catccgctta cgagctgcct gtttttgctg tcttcttcgg gtcatccgaa cattttctcc
    29701 ccactcattt tcatcataca tttttttcac caccaatttt tatgtataat agcgttatca
    29761 aacgcttcat attcttattg tagcaaataa ttgtcgctgt gcacattttt atctttgtta
    29821 tttataagaa aatttcacca gttgagatga ttccaagatt gtccgtcgat ttctccttgc
    29881 agctgcattg ttcgttcgtc tatctcagcc atcagtttct ttatttcata taagagcgca
    29941 cggtcttgat attctgattt ttcgcttaat tcatctaatt gttggatcag ccaatcattt
    30001 gtcataatga agttcctttc atttcttgca gtgtaaaggt caagtcttcg atctgctctt
    30061 ttgcctcagt cagtgcttct acgatatatg cttgtttttc agattcttct tcctgcattt
    30121 tctgattttc ctgtactctt tgaataaacc agtcaatccg ctgagtcagc gatggtttgc
    30181 cttccaatga gagatactgc tgataagcaa ttagcttctc ccaacgtttt tcctgggata
    30241 aatacataaa ttgtgctaaa acgaatggcg gaagataggt catatggaat ttatttgcga
    30301 ttcgctgata cggcctcaaa aattcggaaa tcgtatattc ttcttttcct ccagcttggt
    30361 attctttttc cgccacacct gttgtcaata cgattcctag ttctttccct tttaatacat
    30421 gtgctgctcg ttccaagaca ttatcttgcc aaatttttaa atgagcagga gaactatacc
    30481 agtaaaacgg aaactggaaa atgatccgat catgctgggc caagagctgt agttcagtct
    30541 ctatatctat ttttccgtct ggataacttg attccaaatg atgccaagta gctggtaaac
    30601 cagcagaagc ttctttgaaa aattgctgat ttaaagattc ttcgatcgtt ggatggctaa
    30661 tgatgataag tgtacgcatc ccttttcctc ctttttagtc ttcgctttac agtgtagcat
    30721 aaccgccaca agtttctttt gccgatgctt gtcattttaa ccagactaat caggttgtcc
    30781 aagaaactgc ggtttgtttt tccaactgtt ttttcaaggt atccaaagca atattcttaa
    30841 aattttcgtt tttcatacgt ttacgatagt tcgtagccgt ttctccggta ctctttttga
    30901 acattcggct aaatacgact agactattga accctacttg ataggcaata ctttccacgg
    30961 attcatccgt cagagaaaga agaaacgccc ctcgattgat ccgtaccccg atcaaatatt
    31021 ccttgatact ggtacccata tgatttttga atactcgcga caaatggctc cgattgaccg
    31081 ctaaatgctg ggcgatttcc tcaacagaca atttttcagc ataatgtgcc tcgatgtatt
    31141 tgactgtttc aacagctaaa gaggaatgaa ccttttgtac accaccgctg acctttccgc
    31201 catcttttaa aaggactgat aaaaaacggt aggttaatgc tgttaactgt aattcatttt
    31261 ccaaggtttc ttccgtatct ttcatgcatt ctaaaataat gtcgatatat ttttgtatgt
    31321 cagaagagac catcgtgtat tggtcttctc tgaaaagcga ctgccgaatg atttcttctg
    31381 cagcactccc accaaatgaa agccagcaat acatccacgg atcttctcca tctgataagt
    31441 aaaacgtcga gtctcctgga cgaatcaaga acagatcacc ttttttcaat tggaattgtt
    31501 gatttttcac atgataagat cctttgcctt ccatcacgac atgcaggatg taatcattgc
    31561 gaatagcagg accaaaagaa tgaaacggca tcgttttaga gaaaccacaa aaatcaaaat
    31621 acaattcttt ttctacttgt tgatgttcct tttttaaaaa aatcgattgc tccacgtcta
    31681 tccctcctta ctcctttagt ataatgcaac aaaaagttaa ataaaagtca cagaaatata
    31741 ttaaaaagga agcgatttct tgttaagttt aagtcattaa aagatctttg ttattcgttg
    31801 taaccggttt acttagtatt atatattgaa caggagagga atacagatta tgaaaagcaa
    31861 aatgatccaa cgtgtgtcct acgctttagg cgcttttgga cacgacacat tctatgttac
    31921 attaagcact tattttatgg tattcgtgac aagccagatg ttcgcaggaa cagataaggc
    31981 aacgaatgca aaaatgattg ctacagttac aagcttagtt gtaggtatcc gcttagttga
    32041 aattattttt gatcctttga ttggtggcat catcgataat actcgtacaa aatacggtaa
    32101 attcaaacca tggttagtta tcggcggcgt tgttagttcc gtactcttgg tagcaatctt
    32161 taccaatttc tttggcttag ctactcataa tacgacttta tttatcatat tatttgcaat
    32221 cgttttcatc ttattggata gtttttattc atttaaggat atcgcttttt ggtcaatgat
    32281 tccagctttg agtacggaaa caaaggaacg tgaaaaattt gctacgtttg ctcgtttcgg
    32341 ctcttctcta ggtgcaaatg gtactactct agtcgttgtc cctatcgtta ctttctttac
    32401 ctatcttgtt actcataaac atattgaagg cgcttcaggc tggttctggt tcggtgtgat
    32461 tgctgctgtt atttcaggcg gtactgcgat tatcactgcc ttgggcacaa aagaagtcga
    32521 tactgcgatc cgtcagcaaa atgaaaaagc tgggatcaaa gatgtgttca aagcagttgc
    32581 tcaaaatgat cagttgatgt ggcttgccct tgcttatatc gcttatgcga ttgccaatgc
    32641 agcaacaact gccgtattat tctacttctt caaatatgta cttggccaac caactgaatt
    32701 ttggatcgtt ggtctagttg ctgccttact tggtttagta gctgttccac tattcccaat
    32761 gcttacacgc gtcatctctc gtcgctacgt ttaccttgga gggatcgcaa tgatgatttc
    32821 ttcttacttt ttctttacga tcgcaggttc aagtttgcca atcgttatca tcgggctagt
    32881 attgttctac ttccctcaac aattgatttt cttatccgct ttgatgacga tcacagactc
    32941 tgttgaatat ggtcaatgga aaaatggtat ccgtaacgaa gctgttactc tatcaattcg
    33001 ccctttacta gataaaatcg ctggtgcttt gtctaacggg atcgtagggt ttgtcgctat
    33061 cgcttctggg atgactggta atgctactgc tgctgatatc actgctcatg gcgtaacgac
    33121 tttcaaagct tatgcattct atgctcctgc tgctttgatg attttctccg ctattatttt
    33181 tgcttggaag attacattga cagagaaaaa acatgcacaa atcgttgaga aattggaaaa
    33241 caaattggct ccagctgata caatggaaga tgaacttcac gatgcagtag atccttccca
    33301 ttaagaaagg atcttgaaaa tgaagattac agaaaaagat tttggccaag gttatcactt
    33361 gataaccttg gagaacaaaa acaagctagc actttctatc tctgatttag gtgctagaat
    33421 cgtcagttta aaatcaaatg atcgagaatt agttttggga tttgacaccg ctgaagaata
    33481 tatcgaaaaa gatccgtata tcggtgcttc tatcggtcgc accgcaggga gaatcgaaaa
    33541 tggccgcttt tctctcaatg gaaaaactta ccaattagcc acagatccaa aaactggaca
    33601 taatctgcat ggtggtgctc ctggatttga attaaaaaaa tggtcttatg tcattttgaa
    33661 tggcgaaaat gaagcttctg tcatttttac tactacaagt cccgacggag aacatggttt
    33721 tccaggtaca atggatgtgg aaatccgcta tactttgaca aaagataata tctggcgagt
    33781 gacctctcgc ggcaccagtg accaagatac tttattcaat ccgacaaatc atgtttactt
    33841 caacttgacg ggagatgctt ctcagtcaat cgatcaacat gagctttggc tcaatagcga
    33901 agcttatgct cctttgcgaa cagatagtat tcctataggg gtaaaagaaa atgctgcagg
    33961 aagtgctttc gattttcaaa tacctaaaaa attagcgtcc gtttttgcta gtgatttgga
    34021 tcaaaaaaat cttgttgacg gaatcgatca tccatttttc ttaaaagaaa ccggcttggg
    34081 taaagaagcc gctcgcttga ctagccccga taaaagaatc caagtagata ttgctacaga
    34141 tgcttctagt gtggttattt tcactgcaaa tttcggcaca gaaacaccag aaatgcgcaa
    34201 ccgaaaactg gcacatcacg gtggcatcac atttgagact caaacagctc caggtgcaga
    34261 gcgcttctca gcatttggtt cgattcattt aaaagccgga tcagtatttg aaacagtaac
    34321 agaattcaaa atcaaaacaa gaaaggaata actcatcatg gaaatcaaaa gaagcttaaa
    34381 cacaaaattt gccgaaacat tcggacctaa aaaaactaca caatacttct caccaggacg
    34441 catcaatttg attggtgaac acacagatta caatggaggc catgtcttcc ccgcttccat
    34501 cacttatgga acgcaaggtg tagcagcacc tcgagacgat aataaaatat tagtttattc
    34561 cacaaacttt gacgatatcg gtgtcattag ttttacttta gatgagctag aatatgataa
    34621 aaaagcaaac tgggcaaatt acgtaaaagg aatggtcctt aaattaaaag aagctggaca
    34681 ctcaatcgat catgggtttg agttattagt ggaaggaaca atccctaatg gtgcaggact
    34741 ttccagtagc gcttcattag aattattagt aggtgttgta ttagaagatc tgtttgattt
    34801 aaaaacagat cgcttggaac tagtccaaac aggtaaaaaa gtagaaaatg aattcatcgg
    34861 tgtcaattca ggtatcatgg atcagtttgc catcggcttc ggtgagctag atcatgcaat
    34921 cttattagat acaaatacgc tgaaatacga aatggttcca gtgaaactag atggttatgc
    34981 aatcgtcatc atgaatacga ataagcggcg ggaattggca gattcaaaat acaatgaacg
    35041 ccgtagcgaa tgcgaagaag ccttggcacg tttgcaaaaa actttgccta tctcttcttt
    35101 aggagactta gatgaagaag aatttgaatc aactattgac caaatcggcg atgatacatt
    35161 gatacgcaga gctcgccatg ccgtttctga aaatcagcgg actttgaagg caaaagctga
    35221 attagaagct gggaacttag aagcatttgg tcaactgtta aatgattctc accactctct
    35281 tcgctatgat tatgaagtaa ctgggatcga attagataca ctagtagatg ctgctcaaaa
    35341 acaagaaggt gtcttaggtg cacgaatgac aggagctgga tttggtggct gtgcgattgc
    35401 tcttgtcaaa gaagaaaata tacctgcctt caaaaacaat gtctatgatg aatacatgaa
    35461 agttgtcggc tatgctccgg aattttatgt tgcacacatt ggaaatggga caacaaagat
    35521 cgatccagaa gctgttcatg tttgataaaa aaatcaacga tctcagctaa aaacaaatag
    35581 ataaaaataa cctctcagca atttccaaat gtgagccttt tgctcgtatt tgaaaattgc
    35641 tgttttttat tgacacggaa agagaacgtg tgttctaatt gtgttgaaga ggtgattgtt
    35701 atgtgggcga atcaaaatcc ggtatttgtt tatgaaaaag aaccttcaag agatatttta
    35761 tgtattgact gcaaatcttt ttacgcctcc gtagagtgcg ttgaaaagga tcttgatccc
    35821 cttacaacta aattagtagt catgtcctat ccgtccgatt cgacagaaac acggggtagc
    35881 ggattaatct tggcttccag tcctgcagca aaaaaagctt acggcatcac caatatcagc
    35941 cgtgccagag atcttccctt cccctatcca agtgatttat atattgttgc cccaaggatg
    36001 gcctattata tggaaaagaa cagagaaatc aattctatct ataaaaaata tgcagacgaa
    36061 gcgaaccatc atgtctattc cgtcgatgaa agcttccttg atgtaacaaa tagcatggca
    36121 ctctttggta aaacaaatgc gtacgacatg gctaaactga tccataaaga tgtgtttgag
    36181 cagaccggaa tctacacgac tataggaatt ggcgataacc cgctacttgc taaactagcc
    36241 ttagacaatg gctcaaaaga cggaaagcaa atgtttgctg aatggcgtta tgaagatgta
    36301 ccagaaaagt tatggaaaat ctcagatatc actgactttt ggggaatcgg caaacgaaca
    36361 gcaaaacgtc tgaaacaaat gggtatacat tctgtttatg atttagctca cgcggattat
    36421 tatcacttga aaagcaagct aggggtcatc ggtactcagc tttatgccca tgcttggggc
    36481 atcgatcgaa gttttttggg acaagaatat acaccaaaat caaaaagtat cggaaatagt
    36541 caaatcctag atagagatta tacaagacga gaagaaatcg agatcgttat caaagaaatg
    36601 gccgaccaag tcggcactcg cttgagacga tctgcagcaa aaacacaagt agtcagctta
    36661 tgggtaggat actctttagg ctatcttgat ccaaatggca agaccgggtt tcaccagcaa
    36721 atgaaaatcg aagcgacaaa tgctagcaga gatctagcag atgctttatt gaccattttc
    36781 caccagcatt accactacca ggatattcgg cgtgtaggcg tgaactgttc cgacctcgta
    36841 tacgcgacag gtttacagct taaccttttt gaagatcctg aaaagcagat aaatgaagcg
    36901 aaagttgatt ttgttgtcga tacgattaga aaaaaatacg gctttcaatc aatcatccat
    36961 gcgcatagtc tcttgcaagg aggacgcgcc atcgcacgta gttctctcgt tggcgggcat
    37021 gcaggtggta tgagtggatt agaaggtgga aaagatgaga cggacagcaa aaaaattcat
    37081 tgactataac gagtatcgag atcggccatt tggattaaaa tgggggactg cttttgcgat
    37141 ggaagaacta gtcaacggta tcaaaaaaat gaagaagaag cacgcaaaca gcctcttcct
    37201 aaacaacaaa tgacattgca agaaatcgat agtatactga cagaagcctt tttatctcgt
    37261 aaagcagtaa tcattcagct caatttaaaa gatgaatttg gaagactctt ggatgaggtc
    37321 gaagggcact tcattggtga agcctatgaa gattacttta tgattgacca tcagccgata
    37381 ttgtgggaag acgtacggta tattgagtta aaggaaacaa aaaaatggtt tgtgacatga
    37441 gaggttgtga cagaagtgat caacttcaaa aaataagaaa ggatttttcg aaaattgctt
    37501 cttaaatttt tgtggaattt tggcttattt ttcgaagaag caacttctgg aacaacgtat
    37561 attagatatc agaggttgtg aaaaagtcgc ttagttttga gtaacaagcc aaggcgctga
    37621 tttcacaacc tctgtctatc tatccatcta ttcggtaaga ttcatgcatg acgtcttctt
    37681 tatttagtat gtagagccct ttttcttctg accattcaac ataaatcagc tgttttacat
    37741 ctgcatagcc ttctttcttc aagttctcca taagccatgc ttcagtcaat tgattggact
    37801 gaagcacttt atgctgaatt tgcccttcat ctacaagcag gatcgataaa gctttgtctt
    37861 catctgattt tttcaataca ctcatttgac cggcattctc taggataaca tgtttggcat
    37921 tttcaagaaa aaagcattct tgctgtctta agattgctcg caactgctcc atctcgatat
    37981 ggttatttgt caactctgtc atgttgatga cgccgtcttt gattagaaca gatggctcgc
    38041 ctttgaccca acgattgacc ttttcatttt tttggacgat acgttcgata ccataaatca
    38101 ttactgccca aagcgcaatg gcaaatagga catgccctac atggacattg tcatcatagg
    38161 ttgattcttc taagatccca cctaaaacaa gcgtatagac taaatcaaac ggtgtgattt
    38221 ctgacatgga tttcttccca agcaaacgta ccactaataa taaaccgatc aacccgaaca
    38281 ccagtttcat tgtaattgaa aaaatcattt tttctccccc taactatctg ttaattaaat
    38341 tatatatgct ttctcacgaa cacgcatgga atatacaagg aagaaatgta tccttttact
    38401 aaaaaaagga ctgtgacact gtagtgaccc ccaaaagtta gacttttttg gagtggagaa
    38461 atccactcct tttttttatg ctctaaaatg atatttttac acaaccgtta cggttgtttt
    38521 acgaaattgg acgagacttt gccagtttaa tttctgtttt atccgttcat tattgtagta
    38581 atagatatag ctatcgatgg ctgattttaa ttcctcgaaa cagttataaa ctttcccgtg
    38641 aaaaatctct tgttttaata agccaaaaaa attctccata agtgaattat ctaagcagtt
    38701 ccctttccga gacatgcttt gaaagatttt gtactccttc aatttgtttc tataagcttt
    38761 catttgatac gcccaacctt gatctgagtg aaacgtacga cgatagggac aatcgttagt
    38821 ggtctggata gcttcctcca aaccttccat taccgctaat gcattgggct tttcagagat
    38881 acgataggat aaaatctcac tattgaacat atccataaaa ggatctagat acaatttctt
    38941 ttgacggata atgcctttgg catccacttc atggtattta aattcagttg tatccgtcgt
    39001 gattttctga tggcagatac tggtgtagaa acgacgatgg atccgatttt tggctactgc
    39061 tccaactttt cctcgataag aattgtagcg acgtgattta cgcgtgtatg ccgttacttt
    39121 tattcctagc ttcttgatca agcgctgaac tttcttttta ttgatagaga aaccgcggtt
    39181 tcttagttca ttggtcatcc gtaaacagcc ataatccttg tgcttctccc gaattttaag
    39241 catttccgct tcaatctctt gatctggatt tttacggtcc aatcgccttt gccatccaaa
    39301 taatcatgaa cgatctttaa tttaagttca aaagtatatt taaccataaa aaataccgac
    39361 ctccaaaagt tagatttttt ggtctaactt ttgggggtcg gtacacaaat cgtgtcacag
    39421 tccctttttt gaaaataaac ggtgttcaaa agcttgcatc tgcggtaata agtccagcca
    39481 agttaaaaac ataagaagct gtttttactt ggctgttctt attacttgat gcaaggcagc
    39541 tttttcacaa cctcttttca aatatttcgt tttcttattc tacaaatggt tcttctccta
    39601 acgcttgttg agcggctaga ttcaacatgc tccattgtcg gtcaaagcct ggctggaaga
    39661 agaagtcagc ttctgctagt tcttctaaag tcagtttgtt ttggatcgct agtgccaata
    39721 catttccttg acctgtaaca tcataggtag ataatactgc tcctcctagc aattgatggg
    39781 tcattggatc cgagaataat tggatggaca cttttggatt tccttgttct tctggtacat
    39841 attttggtcg taacgtatct tcataataag acactcgtac atctactcct gcttttgctg
    39901 ctgtaaagct attcaatccg cttgctgcaa aatgatagtc aaagacactt aatgcagagg
    39961 aacctacgac tccgccgaac ggtttgtttg gtacttcttc aaaaagatgt tttactacat
    40021 aacgtgcttc tctacgtgca acagtcgcta aagcgatcgg catttttttg cgtgctggga
    40081 tagaataagc aagtgtagca tctcctactg catacacatc tggaagattc gtttgcaagt
    40141 attcatttgt ttggatccag ccacgttcat ctaagtcgac gatccctttt aaccattctg
    40201 tatttgcctt cacaccggca gcttgaatga ctagatctgc tgggatttct ttttcacttg
    40261 ttttgattgc ctcaactttt ccgttaccag taaaagcttc gatttttgca tttgtcaaaa
    40321 cttcaatacc gttttcattt aggtgttgtt ctaaaatatc tgtcatctca gcatctaaat
    40381 aagtgcctaa aggtctatcg atcacatcaa gcaatacgac ttctttccca gcttttcggc
    40441 ttgcttctgc tgcttcgatc ccaatgtaac ccgcacctac gacagcgatt tttttaatag
    40501 ccggatcatt taatttttct ttgattttgg ttgcccaatt gtatccacgc atcaagtaga
    40561 cattttctag atctgctcct ggtactggca gattgtttgg tttgacacca gaactcaaaa
    40621 tcaatttgtc ataaggatat tcttttgttt cgttatctga tgcgctagta accgttactg
    40681 tttttttatc ggcatcgatc gtttttactt cgtgattatt taaaatatga acattggatt
    40741 gcggaaagtt ttctggtctg aaattacgta catcatttac atctgttacc ttgtcttcta
    40801 aatacagctc cataccacat gacatgaagg aaatatagtc tcctgcttca aatagcgtga
    40861 tatctacatt ttcaccgtat cgtgtcaata gttccaagat cgattgatgc cctccatgag
    40921 atgcacctac aatgacaact ttgatttttt ccattgatga aacctccttg aatattcttt
    40981 taaaatcatt ctaaacaatt taaacttaac attacattag ttatgaatca aaagaaacgc
    41041 gttcatttga actaaattta aaaaacaatc gtctccttgc agaatatacc gcaaaattaa
    41101 cgattgtttt tttgataaaa tctatgaatc actgttctgt taaaaagtct ttgatccgtt
    41161 tgcaggcctc atgtaatttt tccatgctgc tagcataaga aatccggata taaccttctc
    41221 cttctgggcc aaatgcaatt cctgggatac acgcaacttt tgcctgttcc gctaattcta
    41281 cacaaaactg ccaagagtca gtttgaatgg cagctgggag tttgcaaaac aagtaaaatg
    41341 caccgtttgg ctgggtcact tcaaatccta aaggcgccaa ttgctggacc agatagtctc
    41401 ttcgtgtttg atattgctct ttcatattct cgctatcttt caccccattt attagcgctt
    41461 cagccgcagc tttttgcgac atcgttgtag cggcagtcac cagatattga tggactttaa
    41521 ttagttcgtc aataagggct ttttgagcaa aaataaagcc cactcgccaa ccagtcatcg
    41581 catgtgactt ggataacccg cttatcacga ttgtttgttc tggaagataa gtagctatgg
    41641 acatatgcgt tccactataa gtcaattcag catatacttc atcacttata acaaataccg
    41701 gatatttttt taaaacctca gcgattgctt tcaattgttt tgcagacaat gtcgtcccag
    41761 taggattgtt aggatagttt aaaatgactg ctttgacagc tgatccatat tgttcaaatg
    41821 ctcgttcaaa ttgttccggc tgacagacaa accctgtgtc agaagtatct atcgggatca
    41881 attcagcacc agctagttcc actaatggct gatatcctga ataagcaggc gctggaataa
    41941 gaaccttgtc tccttcttcc aaaacagata acaacgcaga ggcaatcgct tccgttgcac
    42001 caactgtcgt caaaacttcc gtttgcggat cataagttaa tccataacgc tgttgctgaa
    42061 atatacaagc cgcttcccgc agttcctcta atcctctcat tccggtatag tgagaaaagt
    42121 cttcttcaat cgctgctatt cctgcttgct tgacatgttc aggagttgga aaatccggtt
    42181 ctcccagggt gagtttgatc acatctggta tcgacgatat ttgctgatcg aattgtcgta
    42241 tttttgatac ttctattcta gaaagcctag gactaaatcg attggataaa ttcatcatta
    42301 tttactcgct cctcttttga actgctatcg atttttacaa gaagattttc tgtaaaaaga
    42361 atcgttttgt accattctac accattttct aaaacatcca tatcaaaatc gaacgtcgga
    42421 tcatgtaaag caggggtatc accgacacct aaaaagaaaa atacacatgg atattgttgc
    42481 gtatatatgc caaaatcttc ggcttgaaga actggagcat ctaattcatg tagtttgttt
    42541 gaatctaaca gtgctgcata taagcctcta tggttgatta cagctggata gccgtcatta
    42601 tagcgaaaag aaatagtagc tgtagagtga aactgttctg ctaaatggtc taatcccctc
    42661 ttcaaataat tttgcatatc tgaactgtaa gaacggatac ttccggatac aataacttct
    42721 ccagctaaaa catttcggat cgttccacct tggatttggc caaatttcat tagatgattc
    42781 cactctgccg gtaattgccg gtcaaaatca taaacattct tcaaaaatcg tacagctgcc
    42841 tccagactat cgattccttt ttcactagaa gcaatatgtg cagactggcc tttaatgata
    42901 atgtctgttt cactgctttg tgccatcaaa ggtcctggtc gagagaaaac ttctccctta
    42961 gctagtccag gccatagatg aaagccaaat attgcttgta cttcatattt atccaacaat
    43021 cctgactgaa taacgctttg tgcgccaccg gaaatttctt ctgatggctg atagatcagt
    43081 actacattat aaataagatc ctcaatgtgt ttagttataa agtcagtcaa ccctaaaagc
    43141 atcgccatat gtccgtcatg accacatgca tgcatataac cttcatgctt agaagcaaaa
    43201 gagagattcg tttcttcttt gactggcagt gcatcgatat ctgttcgaaa agcaatcgtt
    43261 tcttcttgct gattatcaaa ataaaggagt agtcctgttt cgccgatttc atggataacg
    43321 gcctcgctgt tttttacttg ttcatataaa tatttttttg tcttgaattc atgaaacccg
    43381 atttcaggaa tttgatggag tgccattcga tattctttca gcatccgtat tcaccatccc
    43441 ttcatagata cccttcacta ctgtttcata ttgattattc ggtacaccga tgatcagatt
    43501 caactcctgt gctccttgtg ataagatcga tgtgcgaatt tctaatttgt tcaatatcga
    43561 taacactttc ccagataatc caatcaattc tttatgcgga cccccaacga cagagatcaa
    43621 agctaagtct tcgatcacga cgatttcttc cacgccaagt gtttctttta attctttcgt
    43681 gatgagaaat aacttatcgg caatcgcttc tgctgagacg atcactccga tattgtcgat
    43741 ccctgaagga atatgttcga ttgatatctc atgtttagca aaaatgctca ttgctttcca
    43801 gataaacccg atttcatcgg acatatgacg tttgaataaa gtgatggaaa gaaaatcctt
    43861 gcgtccagct attcctgtca gtccattttc cttttctatt tcgtgattcg atatttttgt
    43921 cccttgagcg aaaggatcat tggtattttt tatttggatg gggatatcag cctcttgaac
    43981 tgggaaaaca gctgcttcat gaagaacgtt agcccccata taagccatct ctctcagttc
    44041 tctaaaagag atttcctcga tgattttagg atgatcgatg attcgcggat cagccatcat
    44101 gattcctgaa acatccgtcc aattctcata actttccgct tgcaacatct tcgccagtat
    44161 cgcgccggta atgtcgcttc ccccacggcc caataatttt tcttttcctg cagggttcgc
    44221 cccgtaaaac cctggaacaa ccattttcgg atatctttta aatgcttttg tgatttcctg
    44281 tgctgttttt tcctgatcga ttttcccatc atagtcaaag aaaatcaggt cttttgcgtc
    44341 aataaactgg taaccaagat actcagccat cagttgagca gtcagatatt cacctctact
    44401 tactaaataa tcttcagtta tcttttcgtc ttccagttgt ttctgtatgc gtgctagttc
    44461 atcttcaata ggtaactgca gggcaagaac atctcttact tgaatgaaac gatcacaaat
    44521 ccttttccaa aggggtgtcc aatcaacatg atgctgaagg taagcataaa tcaaataaag
    44581 taagtctgtt actttgtcat catctgacgt acgtttgcct aaagcagaaa caacgatcac
    44641 ttggcgattg ggatctgaaa gaacaattgt acggactttt ttgaattgct cttcatgaga
    44701 catcgatgtt ccgccgaatt tcgctacttt cagcgtatta ctcatcttgc cacctccgct
    44761 attttctgca ttaaagctgc agcaatctgt acggcattcg cagcggctcc tttgcgtatg
    44821 ttatcggcag tcgtatagaa caacaatccg ttctctaaag aagtgtcttt tctgatcctc
    44881 ccaacataaa ccatatctgt tcctctagca agaatgctcg tcggatattt atgtgctgct
    44941 agatcatctt ctaattgaat ccctggaaac tggctgagac actctctaat ttcttccgtc
    45001 gtaaactctt tttgcagttg aactgccaca gagactccat gtccattttc gattggcaca
    45061 cgtacgcagg ttgctgatac tggcaaagca ggctgatgca gaatcttacg ggtctcattt
    45121 atcattttct gttcttcttt tgtataccca ttttccaaag gctgatcgat ttccggaatc
    45181 accgtttggc taatattata aggatacaaa actggttcct cgtcattttg cgtacgatga
    45241 agatcttcaa tgcctttttg cccggaacca gaaactgctt gataggtcga ataattgact
    45301 cgctggatac caaaggcttc ttgtaaagct ttaagcggaa gtaccgcttg aatggttgaa
    45361 caatttggat ttgcaatcag ccgattcaat gtatagtctt ccagattgac ctctggaacg
    45421 attaatggaa tatccgaatc ttcccgccat gctgaggaat tatctatgac aaatagtccc
    45481 tgacttcgtg cgattggcgc aaactctttg gatacagaag cacctgcaga aaatagcgct
    45541 aaatcatatc cttcaaatga agtttctgtc aattcctgta cagtgtgttt ctttttcttg
    45601 aatacacaaa ctttaccggc tgaacgtttt gaagctaata atttcaatcg tcctactgga
    45661 aaatcatatt cttctaacac tttgagcatc gtttggccga ctaatccggt tgcccccaca
    45721 atacaggtat ctatttcgcg catttttctc catctcctct ataattcgcg taacgcagca
    45781 atcaatgctg tattttcttt tgtctgatca tcacttattt ttaatacacg tgcaggtatt
    45841 ccaccgacaa cagtttctgc tgccacatct tctaaaacca ctgctcctgc tgccacgact
    45901 gcatcttttc cgatatggac accttcaaca atcactgcat tcgcacctac cagtacgccg
    45961 tcttctacga taaccggttt ggccgatgct ggttcgatca cacctgctaa gacagctcct
    46021 gcaccaatat ggcagttttt gcccactgtc gctcgtccac ctaagacagc acccatatca
    46081 atcatcgtgt tttcaccgat tactgcacca atattgataa tcgctcccat catgatcacg
    46141 gcattgttgc cgattgacac ttgatctctg ataatagcac ctggttcgat acgagcatta
    46201 atttttttaa tatctagcaa aggaactgcg ctgtatcttg cagcagtttc gatttcgatt
    46261 tcaatgattt tttctgattc agcttctaaa accggagcaa tcgtctcata gtcaccaaaa
    46321 acaacgaagc tgcttccttc accaaaaact ttactttctt taaattcgat tggctcggtt
    46381 acattcagat agactttcac aggcgtcttt ttagatgccg tttgaatgta gcggatgatt
    46441 tcttgagctt ccacgttttt tacacccctt tgtccattaa taaatcttct aatttgtaat
    46501 aacctggtga ctgatctttc aaccagtccg ctgcttctac tgcgcctgca gcaaagattc
    46561 gattagaaaa agattcatgt ttgatcgtaa atatttcatc agtagcagca aacaatacat
    46621 catgttcacc aggtaaagaa cctgcacgaa tactgtgtac accaatttgg ttttcttctc
    46681 tttttttccc ttgccagttg tatacgggct gcagcttttg cacttcttgg attgtttgaa
    46741 gcagcatatt tgcagtacca gatggtgcat cttttttacg actatgatgt ttttcaatca
    46801 gttcgatctg ccagccttgc aacattgcag ctgcttgctt gattagttga ttcatcacca
    46861 tgatgccgaa cgaaaaatta gcactataca tcacaggtac atgtttggca tgttctttta
    46921 tttcttggaa ctgtgattgt gtataacctg tcgtgccaat gactaacgga agttgatatg
    46981 ataagctata cgaaaggatt ttctctaaat tatctggatg agaaaaatca ataagcagtt
    47041 ctggcagttc cgtaaaagca agcgtagttg cttctttagg tgccgtccgt aaaagaagga
    47101 ccgtatctcc tctttcttgt gcaacttctt cgactctatt tcccatctgt ccactgccaa
    47161 tcagtccgat tttcattttt caaccgtcct ttcttttaac aaaagctgag ctaattgttt
    47221 ctttttctct tttgaaagag aaactaaagg caggcgtaga ggtccggaag gtaagtctaa
    47281 taatgacatg gctgctttga caggaatagg attggtctca ctgaacaagg catggatcag
    47341 ttcaagtgca tttaattgct tttcttttgc ttgctgccat cttccgtcct gcgtatcttt
    47401 tactaattca tggactattt taggttggat attcgcccat acacttatta caccgcttcc
    47461 tcctacactc attactggta ggatcaaatc atcatttcca ctgtaaagga agaattcttc
    47521 tccaatcaac cgagcggcat ccatcacata agccatatct cctgaggctt ctttcaaacc
    47581 aatgatatta ggatgttctg ctaaatttac taatacatgg attggaatcg acatgcctgt
    47641 tctagaagga acattataca aaataagcgg aatcggtgag gcttctgcaa ttgctgtaaa
    47701 atgagcagct agtcctgcat cacttgtttt gttgtagtaa ggggtgatga ccaaaagtgc
    47761 gtctgccccc aaagaagcaa aatgcttcgc tttttcaatc gtttctttcg tattattcgt
    47821 tccagctcct gcaatcaccg gcacacggcc agccactttc tttactgtca gttgaaggat
    47881 ctgctcctcc tcagattgtg tgagcgtaga agattctcct gttgtaccta aaactaataa
    47941 tccatctgtt tgttcatcta aatggaattg gatcaatttt tccaaaccag cataatctac
    48001 tgatccctct tcattcatcg gcgtgatcag cgccacgatc gaacctttta tcatcttcat
    48061 tcctccaata ttcttgtcca ttcatgaact gctgggccag ccatttgtat cgcatcctca
    48121 ccagagatca tcaagtctcc ttgttccaag tgaacaacta cctgatctgc tgaaattttc
    48181 ccagtttcct tagcaaccac ataagaggca cagcaacctg taccgcaagc aagtgtccaa
    48241 cctactcctc tttcataggt acggacgatc aattcttgtt cattgactac ttctacaaag
    48301 ttgacattgg ttttttcttt gaacaaagga tgatgacaga tcagttcacc tctttttctc
    48361 cagacttcct cacgcgcatt ttcaacaaaa acaacggtat gaatcgttcc taaaaataaa
    48421 ctagtgatcg ttactttttc accattgatc tctatttcct ggttttttat tggataagtt
    48481 tgattagctt tgattttttc cggagaatca tctggcactc ccatatctac gctgcaataa
    48541 aaaggtgagg gatccaacac cgtaattttt cttgtgcctg ctaatgtctc tacgttgaat
    48601 tcctgttcat tcatcatgtt ctgatcattt acgtatcgag caaaacagcg aatgccattt
    48661 ccgcacatcg gcgcgcggct gccatctttg ttgtaataga tcatttccaa cggatcgatt
    48721 tttacggcga tcaatccgtc tatatcatat ttttcttttg tgcataaaga agcggctaat
    48781 tgactataat ctgtgtcttc tgcgtaatct aataagataa aatcatttcc gcagccatta
    48841 tatttatgaa ggatcatagg aaacttcccc ccttagtaga tcagaaaatg cttgtctgcg
    48901 aacaatcagt cttgattggc cattattgac aaaaacaact gctggtcgtg tcgctcgatt
    48961 gtagttgctg ctcatcgagt atccataagc tcccgtggaa taaacagcta aaagatcacc
    49021 cgattctgct ttcggcaaat aagcttcttt aattaccaca tcgcctgatt cacacatttt
    49081 tcctgcaatc gtcactttct ctgttttttc ttccgacagt tttgctgcta aatcacaatc
    49141 gtattctgcc tgatacagag ctggacggat attatctgtc atcccgccat ctacaaagta
    49201 atatttttta tgtggtgtct ttttgatgaa accaatcgtg tatagtgttg taccagcttc
    49261 tccaacaata cttctacccg gttcgatcag taattgacga atggtcagtt ttcgtttttc
    49321 caaagcttct tccgtatatt caatcagttt ttttagtgcc tcttcgactg ggatcggctg
    49381 atcattttgt gtataacgaa tcccaaaccc tccgccaaga ttcaaggaaa gaggttggtc
    49441 aaaatcggtt aagtaattcg tcaatttgtc gatttcagct aaccaagcag taacatcaaa
    49501 aatttgtgac ccgatatgag catgaaatcc ttctaactct agatagctgc tttcttttat
    49561 caactgaagg gcttgttggc actctttact ttcatagctc atgccgaatt ttgaatcaat
    49621 atgcgcagtg acgatatatt catgagtatg tgcttctact ccgacattca accgaagcat
    49681 gatacagatt ttttttaaat agcgttggct taattctgct aataattcaa cttccatcaa
    49741 attatcggca acaatatgca acaaatcatt ttcaagtgca tagatcagtt cctctggcgt
    49801 cttgttgtta ccatggaagt agatagtatc tctaggaaaa tcagcttgca aagcggtata
    49861 gatttcccca ccactgacaa catctagccc gaatccatat tcacgaacta aatgcagcat
    49921 ctcaatcgtt tggaatgctt tagaggcgta aagcactttt gtatcaaaac gtttcgatac
    49981 aaagcctcgc ttgaatgaca gcatcgtttg tctcatcttt tcttcatcat acacatacag
    50041 aggtgtctta tacttttctg ccaatgtgct tgctgtgact ccgccaatta tcaattctgt
    50101 cattttttca ttcctctttt cacttttttt ccgtttttat tggaatttca tttgataaag
    50161 atttgaattt tattggaata at
//
LOCUS       DADQCX010000010        46135 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.010, whole genome shotgun sequence.
ACCESSION   DADQCX010000010 DADQCX010000000
VERSION     DADQCX010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 46135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.010"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(52..900)
                     /locus_tag="J8R83_000523"
     CDS             complement(52..900)
                     /locus_tag="J8R83_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9573680.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1124..3064)
                     /gene="thrS"
                     /locus_tag="J8R83_000524"
     CDS             complement(1124..3064)
                     /gene="thrS"
                     /locus_tag="J8R83_000524"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAZ9573681.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3401..3580)
                     /locus_tag="J8R83_000525"
     CDS             complement(3401..3580)
                     /locus_tag="J8R83_000525"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAZ9573682.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3627..5450)
                     /gene="cadA"
                     /locus_tag="J8R83_000526"
     CDS             complement(3627..5450)
                     /gene="cadA"
                     /locus_tag="J8R83_000526"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAZ9573683.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5728..8007
                     /locus_tag="J8R83_000527"
     CDS             5728..8007
                     /locus_tag="J8R83_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9573684.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8100..8747)
                     /locus_tag="J8R83_000528"
     CDS             complement(8100..8747)
                     /locus_tag="J8R83_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573685.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8926..9645)
                     /locus_tag="J8R83_000529"
     CDS             complement(8926..9645)
                     /locus_tag="J8R83_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9573686.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9776..10927)
                     /locus_tag="J8R83_000530"
     CDS             complement(9776..10927)
                     /locus_tag="J8R83_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAZ9573687.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11144..11884)
                     /locus_tag="J8R83_000531"
     CDS             complement(11144..11884)
                     /locus_tag="J8R83_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9573688.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11888..12211)
                     /gene="rsfS"
                     /locus_tag="J8R83_000532"
     CDS             complement(11888..12211)
                     /gene="rsfS"
                     /locus_tag="J8R83_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAZ9573689.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12268..12861)
                     /locus_tag="J8R83_000533"
     CDS             complement(12268..12861)
                     /locus_tag="J8R83_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9573690.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12845..13492)
                     /locus_tag="J8R83_000534"
     CDS             complement(12845..13492)
                     /locus_tag="J8R83_000534"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAZ9573691.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13505..13816)
                     /gene="yhbY"
                     /locus_tag="J8R83_000535"
     CDS             complement(13505..13816)
                     /gene="yhbY"
                     /locus_tag="J8R83_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAZ9573692.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13832..14941)
                     /gene="yqeH"
                     /locus_tag="J8R83_000536"
     CDS             complement(13832..14941)
                     /gene="yqeH"
                     /locus_tag="J8R83_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAZ9573693.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14938..15465)
                     /locus_tag="J8R83_000537"
     CDS             complement(14938..15465)
                     /locus_tag="J8R83_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAZ9573694.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15645..16430)
                     /locus_tag="J8R83_000538"
     CDS             complement(15645..16430)
                     /locus_tag="J8R83_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAZ9573695.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16423..17292)
                     /locus_tag="J8R83_000539"
     CDS             complement(16423..17292)
                     /locus_tag="J8R83_000539"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAZ9573696.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17293..18672)
                     /locus_tag="J8R83_000540"
     CDS             complement(17293..18672)
                     /locus_tag="J8R83_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAZ9573697.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18680..19099)
                     /gene="fabZ"
                     /locus_tag="J8R83_000541"
     CDS             complement(18680..19099)
                     /gene="fabZ"
                     /locus_tag="J8R83_000541"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAZ9573698.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19124..19600)
                     /gene="accB"
                     /locus_tag="J8R83_000542"
     CDS             complement(19124..19600)
                     /gene="accB"
                     /locus_tag="J8R83_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAZ9573699.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19603..20838)
                     /gene="fabF"
                     /locus_tag="J8R83_000543"
     CDS             complement(19603..20838)
                     /gene="fabF"
                     /locus_tag="J8R83_000543"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAZ9573700.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20857..21594)
                     /gene="fabG"
                     /locus_tag="J8R83_000544"
     CDS             complement(20857..21594)
                     /gene="fabG"
                     /locus_tag="J8R83_000544"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAZ9573701.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21606..22523)
                     /gene="fabD"
                     /locus_tag="J8R83_000545"
     CDS             complement(21606..22523)
                     /gene="fabD"
                     /locus_tag="J8R83_000545"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAZ9573702.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22630..22854)
                     /locus_tag="J8R83_000546"
     CDS             complement(22630..22854)
                     /locus_tag="J8R83_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAZ9573703.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22907..23869)
                     /locus_tag="J8R83_000547"
     CDS             complement(22907..23869)
                     /locus_tag="J8R83_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAZ9573704.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23879..24319)
                     /locus_tag="J8R83_000548"
     CDS             complement(23879..24319)
                     /locus_tag="J8R83_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9573705.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24625..25590
                     /locus_tag="J8R83_000549"
     CDS             24625..25590
                     /locus_tag="J8R83_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAZ9573706.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25647..25877)
                     /locus_tag="J8R83_000550"
     CDS             complement(25647..25877)
                     /locus_tag="J8R83_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAZ9573707.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25963..26850)
                     /locus_tag="J8R83_000551"
     CDS             complement(25963..26850)
                     /locus_tag="J8R83_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAZ9573708.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26939..28162)
                     /locus_tag="J8R83_000552"
     CDS             complement(26939..28162)
                     /locus_tag="J8R83_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9573709.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28179..29258)
                     /locus_tag="J8R83_000553"
     CDS             complement(28179..29258)
                     /locus_tag="J8R83_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9573710.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29389..31116)
                     /gene="ptsP"
                     /locus_tag="J8R83_000554"
     CDS             complement(29389..31116)
                     /gene="ptsP"
                     /locus_tag="J8R83_000554"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAZ9573711.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31116..31382)
                     /locus_tag="J8R83_000555"
     CDS             complement(31116..31382)
                     /locus_tag="J8R83_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAZ9573712.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31861..34095
                     /locus_tag="J8R83_000556"
     CDS             31861..34095
                     /locus_tag="J8R83_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAZ9573713.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34243..34563
                     /locus_tag="J8R83_000557"
     CDS             34243..34563
                     /locus_tag="J8R83_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAZ9573714.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34768..34992)
                     /locus_tag="J8R83_000558"
     CDS             complement(34768..34992)
                     /locus_tag="J8R83_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAZ9573715.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35190..36770)
                     /locus_tag="J8R83_000559"
     CDS             complement(35190..36770)
                     /locus_tag="J8R83_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAZ9573716.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37171..38547)
                     /locus_tag="J8R83_000560"
     CDS             complement(37171..38547)
                     /locus_tag="J8R83_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAZ9573717.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38675..39793)
                     /locus_tag="J8R83_000561"
     CDS             complement(38675..39793)
                     /locus_tag="J8R83_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9573718.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            39935..40369
                     /locus_tag="J8R83_000562"
     CDS             39935..40369
                     /locus_tag="J8R83_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9573719.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40447..40980)
                     /locus_tag="J8R83_000563"
     CDS             complement(40447..40980)
                     /locus_tag="J8R83_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAZ9573720.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41074..42252)
                     /gene="mutY"
                     /locus_tag="J8R83_000564"
     CDS             complement(41074..42252)
                     /gene="mutY"
                     /locus_tag="J8R83_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAZ9573721.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42245..43042)
                     /gene="recX"
                     /locus_tag="J8R83_000565"
     CDS             complement(42245..43042)
                     /gene="recX"
                     /locus_tag="J8R83_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAZ9573722.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43149..44531
                     /gene="rlmD"
                     /locus_tag="J8R83_000566"
     CDS             43149..44531
                     /gene="rlmD"
                     /locus_tag="J8R83_000566"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAZ9573723.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44705..45283)
                     /locus_tag="J8R83_000567"
     CDS             complement(44705..45283)
                     /locus_tag="J8R83_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAZ9573724.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45605..46075
                     /locus_tag="J8R83_000568"
     CDS             45605..46075
                     /locus_tag="J8R83_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAZ9573725.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT        13177 a         9800 c         8002 g        15156 t
ORIGIN      
        1 aaaactacgt tttgttattc taaaaaactt atataaaaaa tagtaaggtt tttatttcga
       61 atccataaaa tattcttgga ttgcttctcg tgtttttttc actttttcgc taagcttttc
      121 gtttttagcc atatagaaat aaaaaatgat atcgatcgta gcaaattggg ccaaaagtga
      181 attagttgcc gcacttcgat tcgtgatttc ttttggtcta gatgtttgta cgagtacatc
      241 ggctatcttg ctaagcgggt tatttccaaa ttgcgtcaac gcaatgattt cgatattcat
      301 gcttttcgcc agctcggcta atgcgactac atctgcactt ctacctgagt ttgaaacaag
      361 ccaaagcact ttctttttct cattgctgac aagttgcggg agcaagacgt ggatatcttt
      421 ttcaaaaatg attggcttac cgacacgaga ccatttttgc agaatatctt ctactactaa
      481 agaagaggcg ccaaccccat ataaaaaaac agtctctgcc gattccaaac actctacgac
      541 tttttggatc gtttcttctt ctagaatatc tactgtttct tttatcgcta cttgtgcatt
      601 gttaccaagt ttgtttttga tagagtaaaa ggactcattt gcttctatat cactaaaacc
      661 ttcatcgatt ccagtctgta gttctgttga aatcgtgatt ttgaagtccg tcagactttg
      721 aaaaccgatt tttttggaaa aacgtacaac tgtcggcgca ctcaacccgg aagcttctgc
      781 taattcatta gctgtcattg tagggacctt ctcaatatta ccgataatgt agttggccaa
      841 ctttttttct gctgaagaat aatcttccat catactttca atacgactaa ttacgctcat
      901 aagttcctcc acccttttaa tgatagtcta tgtaagtata ccatatcaga cccttattca
      961 cggtcgtata ctggataaaa aacaaaaaaa caatccgccc aacagaatat cttatcccat
     1021 caatcccaca gattctattg agcatctgtg tctttgagga atacctgtta tctattgttc
     1081 ggattgcttt ctatctacta cttttttaca ggaaatttac ctattagttt tctctgctgt
     1141 aatttttgac ttctgcttcc atagcatcaa taaagatatt caaatcttct acagctgttt
     1201 ctttacttcc ataacgacgt acgttcactg ttgcatcttc caattccttg tctccaacaa
     1261 ctaattggta agggatcttt tgtgtttgag aggcacgtat cttatagccc attttttcat
     1321 tacgatcatc aacttctaca cgcaacccct tcatttgcaa acgttctttg atttcataag
     1381 cataatcgcc atgtgcatca acagaaacag ggatgattgt tgcttgtata ggtgccaacc
     1441 atgttggaaa agcgcctttg tatacttctg ttaaataagc gacaaaacgt tccattgtag
     1501 aaacaattcc gcggtggata actactggac gatgcgtatt ttccccgtct tctccaacat
     1561 atgtcaaatc aaagcgctct ggcaataaga agtctaattg tatagttgat aatgtttctt
     1621 ctgtaccaag agctgttttg acttgaacat ctagttttgg tccgtaaaag gctgcctcgc
     1681 cttctgcttc aaagtaatct agttctaatt catccatagc ggctttcagc attgcttggg
     1741 ctttttccca cattgcgtca tcatcaaaat atttatctgt attgtttgga tcgcgatagc
     1801 tcaagcggaa acgataatct gtaatattga agtcagcata tactgccacc atcaattcaa
     1861 gcgtacgttt aaattcatct ttgatttgat caggacgaac aaatgtatga ccatcattca
     1921 acgtcatttc tcgtacacgt tgtaaacctg acaaagcacc tgatttttca tagcgatgca
     1981 tcattcctaa ttcagcgata cgaattggta attcacgata agaatggatc gtgtttttgt
     2041 agaccatcat gtgatgaggg cagttcattg ggcgaagaac aagcatttcg ccatctccca
     2101 tatccattgg cgggaacatg tcttcttgat aatgatccca gtgtccagat gttttgtaca
     2161 actcaacatc tcccattatt ggtgtatata catgttggta acctagacta acttctttgt
     2221 ctacgatata acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc cagaatggca
     2281 aaccagaacc tacttctggg gaaaccatga acaagtcaag ttcttttcct agtttacgat
     2341 ggtctctttc ttttgcttct tcacggagac ggatatattc tttcaaagct ttcttgtcaa
     2401 aaaaggctgt cccgtataca cgttgcatca tttgattgtt tgagtttcca cgccaataag
     2461 cacctgccac tgataataat ttaaatactt gtatacggcc agtggatgga acatgtggtc
     2521 cacgacacaa atcgatgaat tcgccttgtt gataagcagt aatcacttct tcttctggca
     2581 attcactaat cagttctact ttgtacggat cacttgcaaa aatttctaat gcttcctgtt
     2641 ttgaaagaac acggcgttcg atcggcagat tttctttgac gattttcatc atttctgctt
     2701 cgattgccgg caaatcttct gcagttactt ggttttgtcc attatctgta tcgtagtaaa
     2761 accctgaatc gatagctggt ccaacgccaa agtggatatt tggatagagg cgacgcatgg
     2821 cttgggccat caaatgagct gctgaatgac ggactaagcc aagtgcatct tcatggtctg
     2881 gtgtgatgat ctcaatactt gcatcttcct cgattggacg agtcaaatca acgagttttc
     2941 cgttcacttt accagctaaa gctttttttg ctaagctttt tgaaatgctt tcagcaattg
     3001 ccaatgttgt tgttccagac tcaaattctt tgactgcacc atctggaaaa gtaattttta
     3061 tcataatagt ttcctccttg aaatgttttg attgatcaga tcatcaagct gaaaaacaaa
     3121 aaaatcctag catctcttga aaagagatac taggacgaaa agttcgtggt tccacctaat
     3181 gttcaaacgc aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt gcttcaacaa
     3241 gggtttcgaa agtggtcatc ctttggtttt ctcctggaaa agtttcagcc tagcttttcc
     3301 tctcttatcg aagactctca aattcagttg gctttctcat caatcaatta tgtgtttatt
     3361 taaccactaa taaatagaaa aatcaagtgg gaaactaaac ttattttttc cattccccat
     3421 ttacaccgta tgttcctttt ttcatctcat tgatgatgac atggatgtgt tcttttggtg
     3481 cctgcgtgtt tttatgaaca gcttccgtga tatctttcat catattttct aattgttccg
     3541 gactgcgacc ttctactaat tcgacatgta cgaatggcat aatgctctct cctctttctg
     3601 atcgttcttt tttcaactcg attctatcat actatgtttg tcttgggtac tgaatcagga
     3661 aaaatggctg gatctttttt tgctctcaag gcactcaaaa tagagaccgt atccacgact
     3721 tcttgcaaaa cagctccgaa taatgcgggg attagtcccg tacttgcaat taacatcaaa
     3781 aaaatacaaa taaagatgcc aatcagtaca gactgtttcg ctattctcat cgtatctctt
     3841 gaaatcacta ctgcttttgc tacacgcaag agatcatctt tcaagatgac cgcatctgca
     3901 ctttcactag cagctgtaga accatgagcc cccattgcaa taccgatatc tgcagcagca
     3961 agtgctggtg cgtcattcac gccgtctcct accatcgcaa caggtctttg atctttaggg
     4021 atactttcta aaatggtcag tttatcttga ggcaagctac gggcatgtac agaatctaat
     4081 tggacttttt ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat catcatcaaa
     4141 tttttcacat caagttttct tagctccttg attgtctttg ctgcttctgg gcgaatctga
     4201 tccgaaaata ggatcgttcc tgcaaaagat cgatcaattg ttacatagat tgctgtattg
     4261 gacgtttcta tttcttcagc tgaaacaaaa gaggcacgtc caatctttac ttcatgatta
     4321 ttgactactg cttggattcc ttgaccggtc acttctttca gttgactaac aggatacagt
     4381 tggctgtttt tcacgttgtt cactaacgaa cgagctaaga tatggctaga ttcctgttct
     4441 gcactagctg catacagaag tagctcttct ttttttattc cattgactgg ctgaatcgcc
     4501 tctacttcca atatcccttt ggtaagcgtt cctgttttat caaaagcaat cgtttttgta
     4561 cgtgcgagct tttcaatcgt tgttccagtt tttacaacga tcccgttttt acttgaacgg
     4621 ctcattcctg caactaaagc aatgggcgca gctagaatca gtggacaagg tgatgccact
     4681 accagtacct cagcaaatcg taaagggtct tttgagaacc accaagaaat accaccgatc
     4741 aaataagcaa tcaacgtgaa agggactgca taacgatcag ctaaacggac aaatcgggca
     4801 ggcttttctt ttgattcttc gactagttta ataatcattt gatactggct gtctgcggca
     4861 cgtttttcag cgatcatttg gatcgatccg tctccattta aagaccctga cataatctga
     4921 tctccaggtt tcttggtttc cgggcgggac tcacctgtca aagaagattc atcgaccgaa
     4981 gattctcctt tggtcactcg accatctgcg ggtacaagtt cgccaggctt gactagtaac
     5041 tggtcatcaa tatttatttc atcgattact atatcctgca attttccttc tttgaatcga
     5101 tgggcaattc ttggggtgtt atctaacaaa gactgcagtt ctttacccgc tcgtttattc
     5161 gcgtaatcct ctagactatc tccgcccgta agcatgatca atatcatcaa actagcccag
     5221 tattctttga cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc tacgccatat
     5281 cttcctgaac gtaacgtctt gatcatttcc aaaaacatca agaaggcgag aatccctcca
     5341 gtaaatgcga caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc acttaataaa
     5401 gctatcccac caataagcaa agtaagtaaa aattttttga aatgtgtcat tgttttttct
     5461 cctcttttat gtgacttaga gaggttagta ataaatttcc agctgcctct ttcatcttaa
     5521 gcatagtcct tgactagcac tttttaaaac aataggcctt aattgaaaac aactatcact
     5581 atcagcgttt ccaaaattca tcagttctac aaacaaaaat attcagcaag gattactttt
     5641 tcgattcatc agttaaaaag tacctttttt cgaaaaacta tgctatactt ttaattcgtt
     5701 atttacggcg gaaggagcaa acatgcgatg aatgagaaac aactagaaca aacgcacgtg
     5761 gatgaaacga tcgaactaat ccagatcgaa caaaatatgc tggatacaaa acaacaagaa
     5821 ttgactcagg aaatgaatca ttcgacaaaa gacacagcta atcacaagat tcgagctggt
     5881 tccaatgaag ctttttatga atctgctgtt gaatatcgcc aacatgagca ggaattgctt
     5941 ttgaaatacc atactcttga agcacagcaa aaacgcctgc aaacgttgtc tgtcatgaaa
     6001 gatagtcctt attttgcccg tatcgacttt aaagaagacc gtgaaacaga aacattatat
     6061 ctaggtatcg cttctttaag agatctggca gaagaaacaa tcgttattga ctggcgcgca
     6121 ccaattgcca atctttatta tgaaggtgag attggtcccg cattttatga aactgaaaca
     6181 gatagaatag atgtcgatct gcagttgaaa cgacaattta aaatccaaga aggacgtatt
     6241 ttatctatgg tagatacgtc ggaagtaatc aatgatgact ttttgctaga gatattggat
     6301 gaatcatcaa gcaaccatat gaaaaacatc gtctctacga tacaaaaagc acaaaatgca
     6361 atcattcggg acacaacaag taaagtaatg ctgattgaag gaatcgccgg aagtggaaag
     6421 acatccgctt tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa gtggctcgag
     6481 gctgaaaacg ttcttctatt ttcacccaac catttgtttt ctgattacat ctcgactgta
     6541 ttgccttcat taggtgaaag cggcgtgcct acacagacat tcaaaaatta tttggtgcag
     6601 ctgctgccag agttttcttt actagatgaa cagcaacaag aaagtggttt tttgctaggg
     6661 gaaaaagatc cgatacaagt gatgaaaagc ggattgacct tagtcgatca gattgatcgc
     6721 tatatccaag gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat aaatggccgt
     6781 acgatcctat caaaggaatc gattcgccaa tggtataaag aaacaaatga acaattacct
     6841 ttacatcata gactttctct attacaaacg aagctcctga aaaaattagg cggtctgcaa
     6901 aaagacgaaa cacgtcagca atgggtcaaa gatctggcgg aagaacagct ccaagaacta
     6961 tacgcaacag atccaaatct tgaatataca gaacaaaagg agcgttcatt acgtaaaaaa
     7021 ctggccaacc aaatcgtacg taaaagattc cgtcgaatcc atcgagggat catgaattat
     7081 caatttgtca atataacgaa acaatatctc cactttctac aaactgtgcc actttctctt
     7141 ctaacacgac ataaaatcag cgagaccagg tggcaggaac atttgacaac tgttcgtaca
     7201 cacttgcgtc aaagagaatt gcgtcaagag gatgctgtac tattcttttt actgatgcgc
     7261 cgaacatatc cagtgacggt tacacacaaa gctcgctata tctttattga tgaaatgcag
     7321 gatttcgcac catcacaagt ggcattgctg caagccttgt tcccaaaagc aaatttgact
     7381 ttctgtggag atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg atcattggaa
     7441 gaccttttcg tggaccgtga agtcactcgt ttccaattaa cgacaagcta tcgctccaca
     7501 aaagaaatca ctgattttgc taatcatttt attgtgaaag aacatcaagt agaaacaaca
     7561 gcaagaaaag gagaccttcc tttgctcatc caaggaacaa cagatgatat caaattgaat
     7621 tggttagcag ataccattcg aacgactcag ggaaaagccc ggtattggcg tacagcaatc
     7681 atagctaaaa cacaagaaga atgcgaagct ctttatgctc aactgccaga cgagttgaaa
     7741 caacaagtcc agctgatttt aaatgagagt gactttatga agcgttccat tattttactt
     7801 ccagcctttt tagcaaaagg tctggagttt gaccgagttt tcttgtggga tgtagatgca
     7861 gaacattttt cttctcagca agacaaattg atcctttaca ccatgtgtac acgtgcgatg
     7921 catgaattga ccctttttac ctccaataat gaaagtcctt tgttaaacaa tatggatatt
     7981 tcatcttatg agaaaaaagt actgtaagta aaaagacaac tgctatcatt aatgttagca
     8041 gttgtctttt tatttacaat aataattgca gaaaaagtaa ttcaatcatt taaggtcatt
     8101 tattctatat ataaatccaa atctgtttca ggatatttta atttgacaag cgaaataatc
     8161 attttcagtt cttccatgtt ttctggatat tctgggtcaa ataccttgct atgacggcca
     8221 atcccgccat tgtcgatcaa tcggtaaatt cgattccatt caatgaattg gtcaattgat
     8281 tggaaattgc tgattggata gccgccacaa tccaaaatct ctgatacacg aaatgctagg
     8341 tatgcactat cgatcacttt attttttttc gtgtctatct tctcatttct ttcgataaga
     8401 attttttcag gacgatgttt caagctccac tctaatagta gaaagaaagc ctccatccga
     8461 tactcttctt caaataaccg aaaggctgaa tcagaacgac gaaaaagcag cggaatcaga
     8521 taattttgtc tataaatcag cattggtgcg cggtccacca tacactctaa ataacggttc
     8581 agataccctg taccgacata gtttcctaat cgatagcctt caacgccgaa tcttgcgtat
     8641 ttttgcgcta attttgaaca atcagttacg ttcacagcta actcttctac tttgcggtaa
     8701 ccgcttaaga tacgttcaaa aggttctaaa gtgatttttg cttccatatt cttccccgtc
     8761 catcttccac atacttcata tcatttcaca tgatacttat gctctcatca taccacaggt
     8821 tgaattagaa aagaaaataa atcacacaaa aaagcaagac aatctgttag tgagattgtc
     8881 ttgcttttcg aaaaagactg aatacttttc gttaaaactg gttgcttagt cttctaatgc
     8941 cacattatgg aacacatgct gtacatcttc tagatcttcc agtgcatcaa tcattttttc
     9001 aaatgtttct tgatcttctg gagatagtgt tacctcgttt tgagggatca tttggatctc
     9061 agcgattgaa aaatcagtga ttcctttttc ttttaatgct tcttgtatac tatggaaatc
     9121 cgctacttca ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc gaacatcgat
     9181 gtctttttcc attaggtatt caaggatctc gtcagcgtct tctcctgcaa aagcaaagat
     9241 tgctgtattg tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc cgccattttt
     9301 cccaaatgct gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca atgtatcaac
     9361 aatcaccatt gagccgcttg gtccaaatcc ttcatagcgc aattcagagt atgtttcatc
     9421 tcctgcacct tttgcttttt cgattgctcg gtcaataata tgttttggta cattataagt
     9481 tttagcgcga tcaatgacga aacgtagttt ttggtttgca tgcggatcag gatcacctga
     9541 ttttgctgcc gcgtagattt caatcccaaa ttttgcataa atccggctat tattagcatc
     9601 tttagcagtt ttctttgcta cgatatttgc ccatttacgt cccatatttt cacttcgctt
     9661 tctgatttga tagtttcata acgcaaaaac gtcctgttcc attatacttg tgaatcacga
     9721 ttctgtgaag ctttttttct ttcttccttc attcttctca tttttagtca attatctata
     9781 ctcggattgg gatttgcccg aaattctgtt ccggaatatt gcctcccaat tgatagattt
     9841 gatcacttct aactaacagt tccgcttctt gtgcctcttt ttttccgatt cgggaataaa
     9901 tagaaatctc ttttttttct tttaagaatc ttcttccagc atcggtaaat ccaagtagtc
     9961 gaagataatt tttattttgt tggacaggaa tctcttgctt tttgatattc agcaagacat
    10021 aacaagataa tcgttggatc cgtgtccatg tatatctttt tgtttttacc tttgacacaa
    10081 aatcctcaaa actatcagca gttgcagctg ctgttttcat gcgcgattct attccttcgg
    10141 tcatctgata gatatctgtc agttccagca aagtagaaga taacaaccga taacgcaaat
    10201 acggccaata agattcccaa gtctgcagcg aacaagttga aagatcttct tctgtctgag
    10261 gcggcacaag tccagctatt ctttttcctt cttctaacgc atggcgaatg gctgttgcac
    10321 tggctatcct ctgatctgtg atgatttttt catgatagcc tgcactttta cgtcggatcg
    10381 gatgtaattc catagggtgg acatacttgg cattttcctt tgcataactt aatcccaaga
    10441 tatgatttgg cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga aaaacctcag
    10501 tcattttttg cggataacta tacgtttgat cagacagttc ttgaaatgcc tcttctatcc
    10561 tatcttgatt ctcttggaca aagcgtccga aactgctgta atcaaacgaa gtctcttctt
    10621 ctgttccaaa acacaaactg tcacagtcca gtgtttgcaa gatttttact gcacctttag
    10681 caaaatagtc agctgactga accgcccatt cgacgggaag ctccactact aaatccacac
    10741 cattttgtaa agcttcattc gcgcgatgcc atttatcgat gatagccggt tcgcctcttt
    10801 gcaaaaaatt cccgctcatt acagcaatga cgacctctgc tcctgttatt tttcgtgcca
    10861 tttccacatg atagcgatgt ccattgtgaa aaggattgta ctctacgata atcccgcagc
    10921 ttttcatgca catcctcctt catagttatc gataaaaaag aaatagagac aagtaaaaaa
    10981 aggcaaaaat cggaaaaaat acccgaacta tataaactat tctcgcaaac acaatacttc
    11041 tgcgacgaaa agctgcactg caagagcaat gcctatatcg ttcggatata taatttatgt
    11101 tgaagattta ttcttttctt gttaactcga gcaggcaaaa ccgctagtct ttgtatgcta
    11161 caaagaacca gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca gaaaatgctt
    11221 cgactttcga aaagccgctg ttttccagca ttcttaaata actttccaat ggataggtac
    11281 gctcttgatg tagttcatct tcacgaataa atcgaccaga cccttcttgt tcttcaacga
    11341 aaaaggtaag aaaatgttcg atgctgtgtt tctcgcttcc tggataacta tcccacaaaa
    11401 aagcaaaatt atccccttga taatgatagc tatattctgg aaaaacctca tctacttgat
    11461 aggtggagtg tacgtcaaat aaaaatcggc cattttcttc taacgcttga tagacttcat
    11521 caaacacttg ctgtacctct tgtctatttt tcatatagca cagcgaatca gaaaaacagg
    11581 taattgcctg atattgtccg atttctgata aatcgagcat attgccttcc acaaattgga
    11641 tcgatgcgtc ttcttcatat gctcgctggc tggcaatcat caacatctct tctgaaaggt
    11701 ctaaccctgt cactttatat ccatcttttg caaaggcaac cgctaatgct ccagtaccgc
    11761 atgccagttc caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa aaagctaacc
    11821 attgctgata aagtgtttcg tccatcactt catcgtaaat gaaagcaaat gtttcataag
    11881 ccatatgtta atccaaccat tcactaagat cgactagcgg agcatctgac catagttttt
    11941 ccagattata gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca tctccaagat
    12001 cgatcaatac ccattttccg ccttcttttc cttcaatacg ttttacttca tatttgtttt
    12061 cttcttcttt atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg ctatttgctg
    12121 aacagatcat gaaataatct gccaacaagg aaacatttcg aacgtctaaa gcgataatgt
    12181 cttctgcccg ttttgaatct gctgcttcaa tcgcaatttt taattgttct ttactatcta
    12241 tgatgatttc ctcctaatat gagcagctta tttttttgct acccagtaat tatatgtttc
    12301 gattgttttt ggataaatct gttgttcttg cgcaagcaaa tgggccaatg tatgttttgt
    12361 ttcaaatgct acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat cttgtacccc
    12421 aggaaaatct cgacctggtt caatatagtc tgctacataa atgattttgt caaggagact
    12481 catcttagca gccccagtcg tatgcacccg gattgcatga agaatctctg catcggtgat
    12541 tcctaattcc cgctctacaa acgaagcgcc aacaagacca tgccagattg cattattata
    12601 attcaataac tccggatcaa aaccgtctct tacgattacc attttgaact cctcatctgg
    12661 tcgttctttt gcataatcat gtgtcaatgc agcaatacta gctttttcag gagaagcacc
    12721 gtattttttg gcaagagcca cggctgtttc ttctactcca agcacatgct tgaagcgttg
    12781 ttcgctcatt ctcatctgta ttttttgcat caggttttct ctagaataag cagtatattc
    12841 attactatag tccatattca tacaaccctt cattttgaat ataatcaatt actttatctg
    12901 gaacaaggta gcggatagaa cagccttctt tgatcttttg acgtattttc gtggaactga
    12961 tgtcgatctc aggtacatct acccaaatta caggatatgg agtatccgtt gtgtatcctg
    13021 gtcgacgtat acccacaaag ttgaccatag aagtcagctc atcgatttta taccattttg
    13081 gcaaatattc taccatatcc ccaccgataa taaagtaata atctgtatcc ggattgtttt
    13141 gcgtcaattc cttcatagta tcataggtgt aacttttccc accacgagct aattcaatcg
    13201 tttcaatctg caaaaaagga ttgtcttcca ccgctaattc caacatgttg agtcgatgtt
    13261 ttgcatcaat cgtctgtttc tcatcaacat gaggtggctg ataagaaggc atcaaaaata
    13321 cgcggtcaag acctaaattc cggccagctt gttcagccat cactaaatgt gcaaggtgaa
    13381 cgggattgaa tgttccgccc aagatcccta cttgcttttt cttctctaag aattgaggca
    13441 tttcttcagg aaataattgt gaacgaacaa atgtcttagc ttgcgtattc atcatggtca
    13501 ctccttatat tgcttttact tcttttgata gcctttgata cttttctttt gtggaaggtt
    13561 tgtataatac aataacacgt ccaatgattt ggacgatttc gcaatctatt tctttttcta
    13621 atacttgagc tgcttcttct gcaatctcat ctgtattttg aagtaacgat actttgatca
    13681 gttctctttt ttctaaagct tcttcaattt gaacgatcat tgctgaattg atcccacctt
    13741 ttccgatttg aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa cgcttttgtt
    13801 ttcctcttaa actcataatt ttccttcttc cttaaatcaa tgctttgcgt ttcaatacat
    13861 ctacaccctt tggcgcccag cccgcaatta ctactggcgc tgttacagtg atccagccta
    13921 gaccggcaaa aacgatgtct gttttttctt tcacagaaaa ctcaaaacga acaagctccg
    13981 gaaatgcctc gacttcatca ggacgaggag gctgtaataa tccacctaca tgtttttgat
    14041 aaaattcgtc tgctttttcc agtttcgttc gatgaatatt tacatcattt gacacataag
    14101 caataaatga agcacgattg ccgctgataa aatcaaatct tgcaagtccg cccaagaaaa
    14161 gtgtttgccc ttcattcagc tgataaactt taggtttgat ttcttttaac ggtgcaatga
    14221 tccgcaaatc ttttttacct aagtagtgcg ccatttgatg gcgatggata attcccggtg
    14281 tatcaatcaa aaaatgcccg tcatctaaag gaatctcgat tttatccaag gtcgttcctg
    14341 gaaactgcga agttgtgatt acatcttgta ctcccgctgt atttttgatg atttgattga
    14401 taagcgtcga ttttccgaca tttgttactc cgacgatata gacatcccgt ccatcgcggt
    14461 attcttcgat tttttctaat agttccgtca tctcatgaga tttcttagca ctagttaata
    14521 atacatctac tggacgaatt cctgcttcgt aagcacgttc cttcatccat tgtgttaatt
    14581 tagttttttt caatgattta ggtaatatat ccactttgtt cccaactaaa agtactggat
    14641 tgtcaccgac aaaacggtgt agtcctggga ttagtgaacc attgaagtca aaaatatcca
    14701 ccacattgac gatcaatgca tctttttgcc ctaattcatt cagtaagcgc aaaaagtcgt
    14761 catccgtcaa tgagacatct tggatctcat tataatggcg taatctgaaa caacgctgac
    14821 aatagacttc cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg tatcctaatt
    14881 caccgggttt gtttgtttgt ataacggcac cacagccgat acattgtaat tcttctgtca
    14941 ttcgattcca cctcgccagc ccatatcagg gtgttttgct aatagatagg ccataattct
    15001 tttttcccaa aaacgattaa attgtgtctt ccaactatct gttgcgataa tgggttttac
    15061 aaggatgcta cgtatccctg cacgattggc tccacgtata tcagtcataa tctgatcgcc
    15121 taccattact atctcatcat ctgctaaatc caattgtttc tttgctatgt tgatccctct
    15181 tgctaaaggt ttcattgctc gtgcaacata caaaagatca aatttttcaa tcgctcgcgc
    15241 gacacgtttt gaattattgt ttgaaacaac aacaacaggg attcctgcat ttttcatttc
    15301 taaaatccaa gtaagcaact cttctgttcc atctggatta ttccatgcaa tcaacgtatt
    15361 gtctaaatcg gtcaatactg ctttgatgcc tagattcttt aattgggcag gtgtaatctg
    15421 atagatggct tctaccatcc atgttggttt gtaatttgaa aacatgctgt ctcctcatct
    15481 gcaaaaaatg aaggagcaca taaagtactc ctcaaccccg tattatactg catatcagca
    15541 aaaaaaacta cctctatact cgttcgtctt tcagaaaaag catttcttta caaaatgacc
    15601 aaaaataaag attgatcaca gaaaaattta gaaacaaaaa acaactaata ttggcggaac
    15661 ctcttgtatc gtttttccag taatttatgc tgatctaatc gaacaagttc cgtcaatctt
    15721 tcaatcaacg cttttttcat aatgtgtgcg actttatatc gtggcaactg ctcgccgttg
    15781 aacgtttcag gaataactcg atcaacgatt cctaactcgc gtagttctgg cgcagtaatt
    15841 ttcatcaact cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat cgacgcaaat
    15901 ccttctggag aaagcacagc ataaatcgtt tcttccagca tccagacttc atccgctaaa
    15961 cctagagcaa gggcaccgcc acttccacct tcaccaatga tgatggcgat gatcggtacc
    16021 tttaaatcag acatttcgag cagatttctg gcaatagcct ctccttcgcc gcgctcttct
    16081 gctcctacac cgcaatatgc acctgctgta ttgatcaagg taatcaccgg tctattgaac
    16141 ttttccgctt gtttcatcag tcgtaaagct tttcgatagc cttcaggatg gggagaacca
    16201 aaatttctgc ggatattttc ctgcagatcc cgtccttttt gaataccgat cactgttacc
    16261 ggtttgccat ctaatcgagc gattccacca acaatcgctt cgtcatctgc aaataaacga
    16321 tcaccatggc attcctcgaa agaatcgaag atctcttcaa aaaaatccaa gcttgtccat
    16381 cgttctttag ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac gatctatcca
    16441 tcctttctgt gtatgcaatt caagaagcgt atggattttc tgtttcaatt ccatgcgggg
    16501 aacaatctga tcgacaaaac catgagataa taagaattca gccttttgga aatcttctgg
    16561 aagttcctgc ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga tcaagctttg
    16621 gggttctgct agaataatat cgccttccat tgcaaaactg gcagttactc ctccggtcgt
    16681 cgggtccgtt aaaacagtta gataaaaaag accttcattg ctatgccgtt tgacagcagc
    16741 agagattttt gccatctgca ttagagaaaa gattccttct tgcatccgtg cgccacctga
    16801 agctgtgaac aagacgactg gaagactttc ctttgttgct cgttcgaata atctggtgat
    16861 cttttctccg acaatcgttc ccatacttcc catgataaaa ttaggatcca tcactccaat
    16921 aatgaaggga atcccctgaa tggttgcttt accagtgagg actgcttcat gaagtcctgt
    16981 tttatcttgc atttttttaa ttttttccgt atattcggga aatgctagcg gatctttggt
    17041 tacaagatcc gtatcccatt cttcaaaact tttttcatca ataatcaaag ctagacgctg
    17101 ccatgcaccg attcgaaaag cgtatccgca atgagggcat actttttctt caccgatgtc
    17161 tttcgtataa aggatatgtt tgcaatttgg acactttgcc cacatgttat caggaacaga
    17221 tggcgagtta gcaggtttgc tctctctatt aggattgatc cgaatatatt tctttttctt
    17281 aaacagagcc atctatgcgc ctcctatctc cgtttctggt gtccaattcg gtaaaaattc
    17341 ttcttgtaaa aatgctgtgc tgtaatcacc tgctatgact gcaggatgac taatcaaatc
    17401 catctgaaat tctgcgttcg tgatgattcc ttctgtgata aattcactta aggctcgctg
    17461 catcttcatt aatgcttcaa aacgcgtatt tccatggacg attatttttg caatcattga
    17521 atcataatat ggcgggatcg tatatcccgg gtaaactgca ctgtctactc gcagtcccat
    17581 cccacctgct ggaagcagta agttttggat cttccctgga gaaggagcaa aatggaaagc
    17641 aggattttct gcattaatcc ggcattcgat tgcgtgtcct tggaatacta cttcttcttg
    17701 acacacattc aaaggctcac cggctgctat ctccacctgt ttttttacta aatcgattcc
    17761 tgtgaccatt tctgttactg gatgttccac ttggattcga gtattcattt ccatgaaata
    17821 aaaatcgcct tcttcatcca tcagaaactc gatcgttccg gcattttcat aattgactgc
    17881 tttagctgct cgaacagcag cgtctcctag tgcttctctt tttgtttgtg agatcactac
    17941 agaaggagat tcttccagta ctttttgatt gttgcgttgt aaagaacaat ctcgctcgcc
    18001 taaatgaatg acatgaccaa atcgatcacc taagatctga acttctatat ggcgagcagg
    18061 ataaatgatt ttttccaaat acatatcatc atttccaaat gccgctgctg cttcttgctg
    18121 agctgaagaa aaatgctgtg ggagctcttc ttttgattga actttccgaa tgcctttccc
    18181 gccaccacct gcagctgctt tcagcatcac tggataacca attctgtctg ctatttccaa
    18241 tgcttcttct actgtagata atacaccagt acttcctgga atgactggga catttgcttc
    18301 ttgcatcaat tgacgcgcat tgatcttatt tcccattgca tcgatcgttg cacttttagg
    18361 accaataaat gtgatattgc actcttcaca catggaggca aatcggctat tttcagataa
    18421 aaaaccaaat cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc tcagtacttc
    18481 ctgaacattc agatatgaat caacggcttt tgccgggcca atgcagattg cttcatctgc
    18541 taactgtgta tgaagtgctt cggcatctgc ttctgaatat atcgctacgg tttggatccc
    18601 tagttcgcgg catgcacgaa tgatacgtac agcgatttca ccgcggttag ctatcaatac
    18661 tttagaaaac atatttcacc tatccaatca taaaggttaa ttccgcttcg gctacttttt
    18721 taccgtctac tttagcgatt cctttgccta ttccggctga agctttcact ttcaatatct
    18781 caacttcaag gtataaggta tctcccggtg taactttctt acggaatttt gctttgtcca
    18841 atccgccgaa ataagccgtc tttcccttga attgttcaag agaaagtaat gcaactgctc
    18901 ctgcttgagc cattgcttca acaatcaata cccctggcat aacaggttct tctggaaaat
    18961 gtccttgaaa aaagggctca ttgatcgtta catttttctt agcaacgatc cgttctcctt
    19021 caaccatttc ttccactcga tcaatcaaaa gcattggata acgatgtgga atgatttctt
    19081 ttatttcttg tatgttcatt gttttccctc tttcctgctt tgcttatttt tgctgaatcc
    19141 taaagagtgg ctgtccatat tcgacaactg actcgttttc tacaaggatt tctgtgatca
    19201 ctccgtcggc ctcactagtt atctcattca tcagtttcat cgcttcaata atgcagataa
    19261 cttctccttt ggcaacttga tcacctactt ttttgaaagc tggtttgtcg ggcgctggtt
    19321 gcagataaac gattcccacg attggcgaaa caacctcgat tccatcaaat actgccgatt
    19381 ctttttcttt cattatttct ggagcagttg ttgcttgttc agatatgaca ttgactggct
    19441 ccgaaactgg caacgtttcg tttgtttgaa ccatattcat gcctcgactt gttttatttt
    19501 tattcatata caattcaaat tgaccttcac gcaaatcgaa ttccgttagc gaggattgat
    19561 caaattgact gactaattct ctgatttcat tgatatccaa aattattcct cccagcgttt
    19621 catgcacaga accgcattat gtccgccaaa ccctaatgaa ttactcattg cataagtaaa
    19681 acttgcaggt ttgctttcgt ttttgacaac tgtcaagtca atctcaggat cttgtttttc
    19741 tacattgatc gtaggtggga taaattgatg ttctaatgcc agcaaagttg ccaaggcttc
    19801 gatcccgccg gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc tgacgtaagt
    19861 atctctgaaa ttttcaccta atgcgatttg gattgctttt gcttctgcct ggtcattggc
    19921 tggtgtactt gttccgtgag cattgatata tccgacttgt tccggctgta caccagcttc
    19981 ttccatcgca agcttcattg ctttagatgc accagaacca tctggagtag gagctgtcat
    20041 atggtaagcg tcacagtttg caccgtatcc aacgatttct ccatagattt tggcaccgcg
    20101 agcttgtgca tgttctaaag attcaagaac tagaacgcct gctccttcac ccatcacaaa
    20161 accattccga ttttcgtcaa acggaatcga accacgatta ggatcagttg attctgagag
    20221 tgctgttaaa gctgcaaatc cagcaatccc catctcacaa atcgttgctt ctgttcctcc
    20281 agcaagaatg acatcagaat agccatgttt gatgttacgg aatgcttccc caattgaatt
    20341 cgttccgcta gcacaagctg ttacgatagc tgtacaaata ccttttgcac ctacacgcaa
    20401 agcaatattt ccagctgcca tgttggcaat cgccattggt acgaacattg gagaaactcg
    20461 ttttgcacct ttttcatgta gacgaataac ttggttttcg attgttggaa gaccaccgat
    20521 cccagatccg atgatgacgc caaaccggtc ttgattcatt ttttctttat ctaaaccgct
    20581 catctccatt gcttctaaag cagcgtagat tccatagatc gaaaacatat ccattcgttt
    20641 gctatctttt ttaataaaat atttatcgta agggaaatct ttgacttcac ccgctaaggt
    20701 aatccctgtt tctgaagcat caaatttagt gatcggtgcg atgccattcg tcccctcttt
    20761 taagctattc aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc catagccagt
    20821 aattaccact cgattcattt gtttgctctc cttttcttat ccgtgcatga ccaatccgcc
    20881 atcgacattg atgacttgtc cggtgatata tggattttgt gctaagaaaa ctgctgtttg
    20941 tgcaatatct tctacttgtc cgaaacgctg catcggaatt tgcttttccg cttgttcctt
    21001 gactttgtct gctaaaactt ccgtcatatc agttgtgatg aatcctggcg caatggcatt
    21061 acatgtaatg cctctagttg cagcttctcg tgccacagat tttgttaatc ctactacgcc
    21121 agctttacta gctgcataat ttgcttgacc aatatttcca atcaacccag atacactaga
    21181 gagattaatg atggcccctt ctcgctgctt catcattttt ttcaatacgt gctgcgtcat
    21241 attgaaggtt ccaatcaaat tgatatccag acattttttg aaatcttctg catccattcg
    21301 catcacaagt ttgtcatttg tgattccggc attgtttact aacacatgga tcgatccaag
    21361 cttttcttct gcttctttga tcatttgtcc cgctttctca taatcagaga tgtcaccgga
    21421 aactcctacg cattttacac cgaatgcttc gatttcttct atcttttctt ttggaatctc
    21481 tccgcgacca ttcaaaatga tatttgctcc agcttttgca aaagctaagg ccatcgcttt
    21541 gccgattcct cttgtactac ctgtgataaa tacatttttt ccttttacat ccataacgtt
    21601 cctccttata gtattgctat tgtttcatca aatgtctgct tattctcaac acgcagaact
    21661 ggtattgttt tatcgatttt tttcataaat ccgcttaata cttttccggg gccgacttcg
    21721 atgacttgtt cgatgccgat tgtttttaac ttatggatac tctcatagaa acgaacaggt
    21781 tgcatgactt gctgttcaag tagtcccgcg attgtttctt tcttcattat ttccgttgtt
    21841 gtgttgctta tgataggaaa agaaggttca gagaattgaa tctgacttag gtccttcgcc
    21901 agtttttttg ctgccggttc taaaatagct gtatgaaaag gcccgctgac atttagaggg
    21961 atcattcttt tgaacccttt ttcttttaat agtaaaacag cttcgtctac tgctttttct
    22021 tcgccaccaa tcacgatctg ctgaggtgta ttataatttg caggagatac gatgccgtac
    22081 ttgctagctt catgacagct ttcctcgatc gtttcaatcg gcgcattcat cactgcaacc
    22141 attttcccgc ttccagctgg ggtagcttct gtcatataag cgcctctttt tgctactaac
    22201 gcaactgctt cagtgaagga tagcgcatta ctagctacta atgccgaata ttctcctaaa
    22261 ctcagtccta aagctgcatc tgggatgatt ccatgctcct tcaataagcg ataatacgcg
    22321 atgctgactg ttagaatagc tggctgtgta tattgcgtct gatccaaacg ttcattttct
    22381 gtaaagcaaa gttcagccat atcgtagccg agaatctcac ttgcttcatc aaatgtctgc
    22441 tttacaacgg cttcttcata taaatctttt cccatacctt gatattgtgc accttggcca
    22501 ctaaataaga atgctgtttt catgtttttc tccaatatat ccagaatata tgtttgattc
    22561 ttcctattca aaaaggccga gacattccta tttcaggaaa tgtcccagcc cccaacctaa
    22621 ttttaatgat tatgcagttt gtttttctac gtaagtcact aaatcttgaa ccgttttgat
    22681 tccgtcttct gtttcgattt tcacgtcaaa ttcatcttca atttcattga tgatttggaa
    22741 taaatccaag ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt tgatttcttc
    22801 agtttctttt cctaattctt ctgcgatgat ttcttgaatt ttttcgaata ccataataat
    22861 atattcctcc gatattgttt gctttttatt tttataattt aacagtctac aactccatga
    22921 gaatacttcc ccatgttaaa cctccgccat agcctgtaaa tattactttc tgctgttttc
    22981 ctaaggtgat ctttccacta gaaactgctt catccaataa gatagggatg cttgcagcag
    23041 atgtattccc atatttatcc atattggtca ggaacttttc ttgcggcatc tttacttttc
    23101 gggcaatttt ctcaataatt ctgaggtttg cctgatgcaa aagcagataa tcaactggtt
    23161 tgtctttcat gacttcttgg atattgtttg caacgtctcg tacggcaaaa tcaaaaatat
    23221 ctctgccagt catttgcaaa taatacgaac cttctgaatc ttctgaatag aacggatttt
    23281 tattttgctg gtagccagcg gtcaatgagc tacttctggt accgtcagct gctaattttt
    23341 ctttcagcaa ttttttctgt ggattcgctt ctaagagaat cccacctgct ccatcgccaa
    23401 acaacacagc agtcgtacga tcagaccaat cgattagctt agatagtgtt tcaccaccaa
    23461 tcaccagtcc cttagttgag ccgcagcgga tcattttttc agccatgctt aacgcataaa
    23521 caaatcctga gcacgcagca ctgatatcaa aagcgatagc atgagttgct cccaatttcc
    23581 cttgtacttg tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt gctactaaaa
    23641 taaaatccaa atctttaggg tttagatttt tctgttttat caatttttcc gccactaaaa
    23701 tgcataaatc agaagtctcc tgatttgtta cacatcttcg ttcacgaata cccgtccttg
    23761 acgaaatcca ttcatcagag gtatccatca tcttggaaag atcattatta gtaataatct
    23821 tttcaggaag gacgctggct gttgcagtaa tcattccaaa ttgttccatt aaatatcctc
    23881 acttatagtc ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag gcatgctgtt
    23941 cctccgtagc cattccgtct aagatgttct tgaccatttc acgatgaaaa tgctgatgga
    24001 cccgaaatag taactttcct tttttcgtta gtcccaactt tacaacgcgg cggtcatctt
    24061 cactgcggat acgttcgaca tagccttttt ttactaactt gttaatagca gtggtcaagg
    24121 tcccaacagt aattgatagt tctttggcta cttctgaagt tgtttttttc ttgtacatcc
    24181 cgattgcctc gatcgtgtgc atctctgtga ttgacagatc tttgaattga gattttttca
    24241 gctcagactc ttcgattgtc aaaatatcat tgaagacact aacaagataa tcatttactg
    24301 tttttaaatc tggttccatg ttccaccgtc cactaattag tttgattatc aaatcttttg
    24361 atgttcaaac tatatcttaa cttttttcaa aatgcaacct taaaagatca tttttttact
    24421 atatgagctt tttttaagat tttactcatt taaaacaact gataaatcag catttataat
    24481 ttcttttatt agaaaaatca tctatctcac atattttgat tatcaaagta ttttctgtga
    24541 acagaactat agaattccct aaaacttgtc cattatttca aaatttgtta tagtcttttt
    24601 attcaaagcg taaaaggaga tcctatgtta aaagaaaaaa tgaaaactct ccccatgctg
    24661 ccgggtgtct atcttatgaa agaccgagat ggtaaggtca tctatgttgg taaagcaaaa
    24721 cggctcaaaa atagagtaag cagctatttt catcagaata aacagcattc aaaaaaagta
    24781 ttacgtatga ttcatcatat aacagatttt gatttcgtcg tagtagacac ggaattagat
    24841 gctttattgc tcgagtgtca attgatccaa cattaccgtc ctttttataa ccgacaaatg
    24901 aattatttca gtaattataa ttatgtacat attaccaata agggatttgt attaacagat
    24961 actcctacgg ctcgaacata cgggcctttt cgtctctata aaaaaatgcc gtctattttg
    25021 cgtataatgg aagaaactta tcaaatgcct tggttgtctg aaattagttt gttagctttg
    25081 cgagtccagc ttcctgacct acaggaaatg acttttgaac agaaaaaaaa ggaactccaa
    25141 gggctgtttc aaggccgaaa taaaaagcta ctgacttact tgaaaaaaag acaacaacat
    25201 ttcatctatc agttgaattt cgaaaaagcc ggtatgcttc aaaaagatat cgaattagtt
    25261 acttatttta ttagacggat ccaggaacaa aagcagtttt taagaacacc atcgctcacc
    25321 ttcagcatgc cattagcagc agatgagagt cagaaaaagc actacctcgt ttgttatggt
    25381 caacttgcag aaacaatgat tacctctggt gacgtttctc ctgacttcta ttatgaaaag
    25441 aaagaagctc atttatcttt gaaacgtcaa ttgtcaaaag aagaaatcga tcctgtacaa
    25501 atcttgatca gttaccgcaa aaaattagaa aaagaacagt ttgaaattga actgttaaac
    25561 aaaaaagaag ctgaaaagca actaaattag ttgcttctcg gcttctttta ggcatcttca
    25621 acttcaaatg tcaattatcc taaaatttat tggattaagt catagatttc catcgctacg
    25681 atatcgatat tatcaaattc gtattgctga tgagtatctg tttcagttaa ttcaaatgta
    25741 tcggtcgctt tatcataagt tactgtacac ttctctacgc cttctttttc aaaacggcga
    25801 acttgcagtt cattatctgc tgactcgacc atagcctcca gtcgttttat gattgcgact
    25861 aattgtgaat gtgtcatcgg aggtcctcct tttcttattt ctgttatatt gtatcaaaag
    25921 catagcctac ttgcattgat tttctctaaa aaaactcgtt ttttatgatt ttttttctgg
    25981 tatttttcct tcaggccacc aaagtttgat caaagcttgg gttccgtcat tctcaaaacc
    26041 tttatctgcc aactcttcat atagtttcaa tgcttgggta gttgctggca atacaagatc
    26101 cattttttct gcttcttcta atgcaatctt taaatctttg ataaaatgtt tgacaaaaaa
    26161 accaggtgtg taatcttctt ttaaaatacg aggagaataa ttgcttaaag accagttagc
    26221 tgcacttcca cctgaaagcg tctcaatcac tttctttaaa tcaagtccgt ttttttgtgc
    26281 atagacaagc atttccgtca ttcctgtcat cgtacctgca atcatgatct gattagccat
    26341 ttttgtatgc tgacctttcc cagcagaacc atgcaatgta aatgtcgtac caaattcttt
    26401 gaataaaggc agtacttgat cataaacggc ttcttctcca ccgaccatga tcgtcagtgt
    26461 accattcttt gctcctaagt caccaccgga taccggtgca tctaacgcat ctgcgccttt
    26521 ttcttttgct gtttttgcaa ttttttctgc caggcttggt gtacttgtag tcaaatcaac
    26581 taaaatatgt cctgagatat ctgcagaaaa aatccccgac tgtccatagt agatttcttc
    26641 tacatctttg gggtaaccta ccattgtaaa gagaatatta ctttgttctg ctaccgcttt
    26701 tggtgtatct gcccagatag ctccttctgt tactaaagga tcagcttttg cttttgtccg
    26761 attatagaca gctacttcgt gtcctgcttc tagtagatgg cgtgcgacag cacttcccat
    26821 gacgcctgtt ccgataaaac caagtttcat tttttcgacc tcctaaaaat caaaaatcct
    26881 tgcttctatg ctagtatacg ctagaaacaa ggattttttc ataaaaaatg tttgaatttt
    26941 atcttttaaa tgaatttaat tttattttga ttcgttcaat cgagtcttct tcttcttttc
    27001 ttcgcatctc ttcttcatga taaacaacca tgtcttgata aaattcgatc atagcttcgc
    27061 cgaaatgtgt agatgaaata tcataaagtt tagcttctaa aacttttgga tctttaggaa
    27121 cttcactgga aatataatca ataagtgctg gtgcaaagtc ttcgtcggtt tcaaaagttt
    27181 tccctaatga aggatgatcg aacaatcggt tcaaataagc atttccttcc acgacacaag
    27241 gtgttccggc tgccatcgct tctgtataag taagcccttg tgtttctgaa gtagaagcac
    27301 tgacaaaata atctgccgct ttataataaa gtgctacatc attgttgtcc acttctcctg
    27361 tgaactgcac aaattcttct aactgcagtt ctgagatcaa ttcctctaac tcttctacat
    27421 aaggtccttt tcctacgata actaatctgg cgttaggata agcggagatg acctgaggaa
    27481 acccattaat caaggcttgg atatttttct cataagaaat cctgcttaaa gaaagaatca
    27541 tcaaatggtt ttcctgaaga cctagtgact cccttaattt gctgatatcc tgctgagtga
    27601 tatcagaacg tttgaatttt tcaatgtcga taccagtagg aatcacgcga agcggtgcta
    27661 ttacaccata gctgcgtaat gtatcaataa cacgttcact tggacaaact acacctgtcg
    27721 tatgatttgc aaataatcta gacaagtatt ttacatggga ttgcctgatc acttttcctt
    27781 taccgatata atgaaggtag tcttcataca tcgtatggta agtatggatc agaggtattt
    27841 tcaacttctt agctaccatc ttcccaagta tccctgctcc gaattctgta tgggtatgaa
    27901 taagatctag ttctagttct ttggcaacca aataagcata ccacatgcct ctaacaacaa
    27961 ctcttcgatc cttgaaagaa ataaatggta cacttggcat tcgaatcaca tctttttcca
    28021 acttatccgc attaggatcg gtcgttgtaa aaatatagac ttcatgccca tgtctttcta
    28081 attcttgttt taatgttttg atcgatgtag caactccgct gacttgcgga aagtaggtat
    28141 cggtaaaaaa gccgattttc atgtttttcg cctccaaact agtccttgac ctgatttact
    28201 ttttttaatt tgctagagac tttttcattc agtacacttt cgtatacatt tttaagttct
    28261 tcaccgattt tattgatact tcgctctttt gctgtttgat aaccggcttg tgtcgtactc
    28321 ggtagttctt gattggtaat ctgttggatc agtcggataa attcttcgtt tgtcttcccc
    28381 atatagcagt tcttgctatc ttctaaccag ccattataca ctggaatatc tcgaacaagt
    28441 acgttttgtt tgcttgctaa agcttctaaa acaacgatcc cttctgtctc ttcataagaa
    28501 gggaaaaaga atagatctgc acctgaatac gcaccttcta tgatctctcc acgaatgtaa
    28561 ccaggaaaca ggacattttc aggatgatct tcttttacaa ttttccggat gttccgagga
    28621 atcgagtaca tgggaacatg accaaaccaa ataaatgtgt attcgggcat cttcttagca
    28681 atttctacga aatcaatgat tcctttacgt tcgaaaaaca aaccgacaca aatgattact
    28741 ttttgatccg gagacagttt gaaatattct ctgaactttt gttctttcat tggatcaggg
    28801 tgatatttct ctaagtcgat cccattggaa atagcttgaa tcggcacacg gataccatag
    28861 ctttccaaca actgttttga ataaggtgtt ggcgtgatca gatagtccgc tttttggtac
    28921 aatcctacca gatatttttt tacgatagga gaaagctggt tcgatccgat aaaggaattt
    28981 cggaaatctt cctctgtaga atgcgcatga tagacaactt tttttccttc tcttctggct
    29041 ttattgacca tattatgact attgattccg tatgtattga tgtgcaggat gtcataatct
    29101 tctttttcat ctagtgtata agagataccg acttccgtca gagcacgttt ttgatgatca
    29161 agcgcacgcc cgattccaga ttttgcaagc atcttttcac tttcaaaata taataatacc
    29221 ttcaccttac gtcccccttc acttatatag tataacatag cctacaaact gtcactcaaa
    29281 cttaagccct atttttgtct attcttactg acaaaaacgt tttcttaaaa aagaacaaaa
    29341 aaactggcgt agctctttta caagccacac cagcttttga tacgttgttt attttacata
    29401 ttcatgaaca agttcaacga cttcttccat catatcgcat tctttcaatg cacgatcagc
    29461 aagttcagcc attttcgctg tgtccaagcg tttcattaaa ctacgcgttt taagaataga
    29521 tgtcgcactc attgagaact catctagacc catacctact agcaatggaa cagctgtttg
    29581 atctccagcc atttctccac acatacctgc ccattttcct tcagcgtgtg ctgcatcaat
    29641 tacatttttg atcaaacgta aaattgatgg gttatatggt tggtacaagt aagaaacgcg
    29701 ttcgttcata cggtctgctg ccattgtgta ttgaatcaaa tcgttcgtac ctacagagaa
    29761 gaaatctact tcttttgcaa acttgtctgc taagactgct gctgctggaa tctcgatcat
    29821 gatgccgact tggatcgtat cagatacttc cttgccttca cttatcaatt tttgtttttc
    29881 ttcttcaaag atcgcttttg ctgcgcggaa ttctttgagt gtagctacca tagggaacat
    29941 gatacgtaaa ttaccatgaa cagatgcacg aagcaatgca cgcatttgtg tacggaacat
    30001 ttcgtcgcct tgttcagata aactgatacg caatgcacga tatcctaaga atggattcat
    30061 ttcatgaggt aattgcagat atggtagttc tttatctcca ccgatgtcca ttgtacgaac
    30121 aactacaggt tttccttcca taccttctaa tacagctttg taagcttcat attggtcatc
    30181 ttctgttggg aagtctggag aatccatata caggaattca gtacggtaca gaccaactgc
    30241 ttctccacca ttattatgga caccaactag atcttttggt gttccgatgt ttgcagctaa
    30301 ttcaaaatgc ttgccgtcag ctgtgacagt ttctgcattt tttaattttt cccattctgc
    30361 tttttgtgct gcgtaatctg cacctgcttt ttcaaattca gctttttgtt catctgtagg
    30421 atcgatgatt acatcgcctt cgatcccgtt gacagccaaa atatcgcctt ctttgacttt
    30481 agcagtaatt tcttttgtcc caacgattgc tggaatttct aaagaacgtg ccatgatagc
    30541 agaatgtgaa gtacgtccac caatgtctgt tacaaacgct tttacaaaat tgcgatctaa
    30601 ttgtgctgta tcacttggag tcaagtcatg tgcaacaacg accacttctt cgttgatcat
    30661 tgatggattt ggtaaagtaa cgcctaataa gtgcgctaaa atacgtttag caacgtcacg
    30721 aatatctgca gcacgctctt gcatataagc attatcttcc attgcttcga acataccgat
    30781 atacatatcc gttacttctt ttagcgctga ttcagcattt acgctgttgt ctttaatatt
    30841 ttgcttgatt tgacctacca tttctggatc tgaaagaacc atcaaatggg catcaaatac
    30901 ttgcgcttct gcttcaccta agctttgcgc tgctttttca cgaatttgct gcaattcttc
    30961 agtagattta gctaatgcag catccaaacg agcttcttca gccgcagtat cttctactgt
    31021 tgccttactg aatgttaaat ccggttgaac tagcaggtaa gcttttgcaa cggctacacc
    31081 gtcactagcg gcaatccctt ttagcatttc aaccattatt cagataagcc ttctttcttc
    31141 attgtttcaa cgattgctgc cattgcatca gcttcgtcag caccttctgc agtaatagta
    31201 acatcagaac cttgacctac acctaaagac ataacgccca tgattgattt caagtttact
    31261 gatttacctt tatactctaa gtttacatca gagttaaatt tgcttgctgt ttgtactaat
    31321 agtgtagctg gacgagcgtg gatcccagtt tctgctacta cgtgaaattc tttcttttcc
    31381 atattaatcg gtctccttta agtgagtgtt gtttttatgt gagggttttc ttttttagta
    31441 attcagagaa tcctaacaaa tgccaccctt tcatctgtaa agattaacat tttttttcgt
    31501 tagatacaac agttttcatt caatttcaga taaaagtatt caaattattc cggattcttt
    31561 ttcatccttt tcttcacatt ttataacaaa cgtgtttatt tcctttttct tgtcgctttc
    31621 tcttctcctg acgtttatca ttctttcctt tgaccctctt tgttttcata tgaaacgaat
    31681 tacttgcttc cctttttatt tttagtataa taagagtcaa aggtcaggaa tggtcaatag
    31741 agatttcacc ttttctacct cataaatctc ttaaaaaact aggggttatt cttttacctc
    31801 atgaaaaacg agatgtaaaa tatggatgta cccatttttg tgaaaggacg tgaatgattc
    31861 atgctttgtc aaaactgcgg caagaatgag gcaacgattc acttgtatgc cactgtcaat
    31921 ggtcagcgga cacaactcga ttactgtcag agctgttatc aaaaaatcaa aaatcaacaa
    31981 aatggaggtc tgactaatat ggcccaaaat gatccatttg gatttggcag tttggacgat
    32041 cttttccgtt ccatgtctcg ccaaatgcaa cagcaaggaa attatgagca aacaccacca
    32101 acacaatttg gcggaaacaa caacttcaat ggtggtcagc cacctcaagg caatacagaa
    32161 ggtttattgg gagaatacgg aatcaatatc acagaacaag cacgacaagg tgatatcgat
    32221 cctgtgatcg gacgcgatga cgaaatcaaa cgagtcattg aaattttaaa tcgccgaacc
    32281 aagaacaatc ctgtcttgat tggagaacca ggtgttggta aaacagcagt tgttgaaggt
    32341 ttagcacaaa aaatcgtaga tggtgatgta ccgcaaaaat taatggacaa agaagtcatt
    32401 cgtttagatg tcgtatcttt agtccaaggt actggtatac gaggacaatt tgaagaacgt
    32461 atgcaaaaat tgattgaaga gatccgtcaa gcagaaaatg tgatcctatt catagatgaa
    32521 gttcacgaaa tcgtcggtgc tggttctgct ggtgatggaa atatggatgc tggtaatatt
    32581 ttaaaaccag ctttagctcg aggagaattg caaatggttg gtgctactac cttaaatgag
    32641 taccgcatca tcgaaaaaga cgctgcttta gaacgtcgta tgcaacctgt acgggtagat
    32701 gaaccaactg tcgaagaaac gatcagtatt ttgaaaggtt tgcaaaaacg ttatgaagac
    32761 tatcatcatg taaaatatac tgatgaggcc atcgaagcag ccgcaacttt atccaatcgt
    32821 tacgtccaag atcgcttctt gccggataaa gccatcgatt tgctagatga aacaggttct
    32881 aagaaaaact tgacgatcca aatcgttgat cctaaaacaa tcgagaaaaa actgcaagaa
    32941 gcagaagaac aaaaagtttt agcttctcga gaagaagatt tcgaaaaagc agcttattat
    33001 cgcgatcaga tcaataaact tcaaaaaatg aaagaacgtc agctcactga agaggaaaca
    33061 cctgtgatta ccgaaaaaga tatggaaaaa atcgttgaac aacggacagg tattccagtg
    33121 ggtgaattaa aagaaaaaga acagacacaa ctgaaaaact tagcagatga cttgaaagct
    33181 catgtcatcg gacaagataa cgctgtagat cgagtagcga aagcgattcg ccgaaaccgt
    33241 gttggattaa acaaacagaa tcgtccaatc ggctccttct tatttgttgg accaactggt
    33301 gtaggtaaaa cagagcttgc gaaacaactt gcctacgaac tattcggttc acaagattca
    33361 atgattcgtt tcgatatgtc tgaatatatg gaaaaacata gtgtctctaa attgattggt
    33421 tctcctccag gttatgtcgg atacgaagaa gctggtcaat taacagaaaa agtacggaga
    33481 aatccttaca gtcttgtctt gttagatgaa gtagaaaaag ctcatccaga tgttttgcat
    33541 atgttcttgc aaatcttaga tgatggtcga ttgacagatg cacaaggaag aacggtcagc
    33601 tttaaagata cgatcatcat tatgacaagt aatgccggaa ctggtaaagt agaagcaaac
    33661 gttggttttg gtgcggcacg cgaaggtgtt actcgttctg tattgaacca attaaacaac
    33721 tactttacac cagaatttct gaaccgtttt gacgggatca tcgaattcag tgcattatca
    33781 aaagaaaact tgatgacaat cgtcacacta atgctagacg atgtcaacca aatgctggca
    33841 gcacagcaac ttcacatcga agttcctacg aatgtcaaag aaaaattagt tgacttaggc
    33901 tatgatccat ctatgggtgc tcgtcctctt cgacgcacga tccaagaaca aatcgaagat
    33961 ggtatcgctg aattttatct tgatcaccct tctatccatg agttgaaagc aaaactggat
    34021 aaagatggaa aaatcatcgt tacttctaaa ccagaacgtt tggctaaaga atcagccgaa
    34081 gaaacggctg aataaatcca gttttatagc gtgagacggt atttctttga gaaatgccgt
    34141 ctcattcttt tttcagaaaa gtcaaaatac tgttcatttt ataaaaaaga aattataata
    34201 agagaaacaa gcaattaaaa atacataaaa gaggtgagcg ccatgaaatt ggtaaatgta
    34261 acaaacagcc attcccgtct tgtattaaac cagcttgaaa acactgatgc ccatctagtc
    34321 aaggtctaca cagccggaaa taccactatt gtctacactg aagcccctga acataatgaa
    34381 attctgctga tcaatgacaa acgtaaaatc cagccgaaag aaatcgaaga tgctaaaaat
    34441 tatttcttag ataaaatcaa agacgccgtt taccacgagg atgaaatcaa agtaatcgaa
    34501 ttggcaggcc ttgttgaaat ctcgattcca aaacatgaat taggcgctac attagccgtg
    34561 taaacaaatt ttgaacataa taattaaaga gcgtgggaca aaagtaaaga acacttttgt
    34621 ctcacgctct aaacacgtat aaacggcgaa agcagaagca actccttcgg aaataagctg
    34681 aaattcacga aaattgcttt tcaaattttt gtgaattcca gcttatttct tggagttaaa
    34741 cgcttctgtc tcagcctctt tttctttcta gctttttgat ttttctcttt tcttttgtac
    34801 ttttctcttt tcattttcag ttctacgcgt gtctttattt ttaacttttt cctctttatg
    34861 gatgattgat cgtacttttt gtgcaatttg ctcgtttttg tcccagtctt ttacatctaa
    34921 taatcgacat aatcgtaaca tctcttcttt tttctgtttt tttctttcac gtctttgcca
    34981 ttctgtttcc atgtgtcaca ctctcctttc tttaatcata tgtacgcaaa ataattttta
    35041 tatttttttg attagacatt tctatgattt taatatagta aaaagagccg tcacggaaaa
    35101 tccgtcacgg ctctaaacaa aatatgagag gctgtttttg tttggctatt cttattactt
    35161 gatgcagggc agcttgtgtc aagacttctt tacatcaaac tttttaattt tacattggga
    35221 tatttatccg caaaccagcg ttctgcaaat tggttctcga ataagaacaa cggttggtcg
    35281 aaacggtcac gagccaagat attgcgactt gaactcatct tctcatccaa atcttctgga
    35341 tcgatccagc gagcgatttt gtgtcccatt ggagacatga ttacttcggc gttatactca
    35401 tttaacatac gatattggaa tacttcgaat tgtagctgac caacagctcc aatgatatat
    35461 tcttccgtta gatatgtttt ataaagctga atcgctcctt cttgaactaa ttgatagatt
    35521 cctttgtgga aggatttttg tttcatgaca ttttttgcag tcactttcat aaacagctct
    35581 ggagtaaatg aagggagttc ttcataagca acttttagtt ttccttcgaa caatgtatcc
    35641 ccaatctgat aattgcctgt atcatataca ccgatgatat cgcctgctac tgctttttcg
    35701 acgttttctc tcgaatctgc cataaattgt gtgacattgc ttaatttcag ttttttattt
    35761 gtacgttcca accagacatc cattcctcgt tcgaatgttc cagaacagat tcggacaaaa
    35821 gcgattcggt cacgatgggc tggattcata tttgcttgga tcttgaatac gaaacctgaa
    35881 aattcttcct cataaggact taccatctga tcatcttgtg ttttgtgtcc ataaggagct
    35941 ggtgccaatt caacgaaagt ctctaaaaaa gtctgtacac cgaagttagt caatgcagaa
    36001 ccaaaaaata ctggtgtctg atcgccacga gcaatttttt cttgattaaa tgcatctcca
    36061 gcctctttga ttagttctac ttcttctaag acttgttcat ataaggaatt ttcagttaga
    36121 ggatgatttt cgggaagcag tccatcttca tccaattcta ctaatcgttc atcctgataa
    36181 ttttccggac gataaaactc tacacgatta tggtagatat cataaagacc ttctagccct
    36241 ttacccatac cgattggcca attcatcgga taagattcga tatctaatag ctcttctaat
    36301 tcttctaaca attccaatgg ttcacgacca tcacgatcta gtttgttgat aaaagtaaat
    36361 atcgggatgc cacgtttttt tacaacttgg aataatttct ttgtctgtgc ttcgatccct
    36421 tttgcactat cgattaccat gaccgcacta tccacggcca tcaaagtacg ataagtatct
    36481 tcagaaaaat cttcatgtcc tggtgtatcc aagatattta ctcgtttccc ttgataatca
    36541 aactgcataa cagaactagt aacagaaatc ccacgttgtt tctcgatttc catccagtct
    36601 gatttggcaa aattacctgt ttttttgcct tttacggtcc cggcttgacg gatagcccca
    36661 ccaaacaata gtaattgttc tgtaatcgtt gttttcccag catccggatg ggaaatgatc
    36721 gcaaaagttc tgcgattgtc cacttgttgc tttaattttg gattattcat aacctaactc
    36781 catttcttcc attcaattat ttatattttc tctaggcaca gattgtccga tctcttaaag
    36841 aaagacaatt tcatataggg ctgtgacaaa agccgtgtag cagtctcttt ttccgagtaa
    36901 acggcgttct agagacagcc tatcagcaat aagcccaccc aagccaaaaa tacgaaaagc
    36961 tgtttttgct tggctgctct tattacttaa tgcaggatag ctttttcaca acctttgtca
    37021 actactacaa ctgaatcagt atagcatgga ttcagcgaat gaaaaagcca ccaaaccata
    37081 agagtcaaat atttttttgt cagctgacta aaagaaaaga cgtgttgctt gtttattcaa
    37141 gcaacacgtc tttcataacc aagtttccaa ttatcttctt ggctcgtcat cttcgaattc
    37201 ttttctgaag tatcttcgtt cttcttcagg ttccgcttct gtttcttccg gatcatgaaa
    37261 aatgacacgg attttaagga ttcgagaacc ttccatttct tcagaaacca gcgtaatatt
    37321 atcgacatca aacgataact tttcgccttc atccggaatc atgcctaatg ctgtaatcaa
    37381 ataaccagcc atcgtatcta catcactcat atgcagatca ctgtcaaaag cttcattgaa
    37441 ctcatcaatc agcatacgtc cttggatgat atattcgtgt tcatcgattt tttcataaag
    37501 attctcaact tcatctgatt catcatcgat ttctccgacg atttcttcta aaaggtcttc
    37561 tagtgttgct aacccaacga cgccgccata ttcatctaat aaaatagcca tctgattctg
    37621 cgtctttttc atttcatata acagatcatc aataaagacc gtttcaggaa cgaataaagg
    37681 ctcctgcatg attttcttga tatctaaatt atcaaagccg aatttatggg cagcttttag
    37741 taaattcttt gtatgaagga ttccgactac tttatctttg tcttcgttat aaacagggat
    37801 tcttgaatag ttttcggata aaacttcatt cacattttct tccacagtgt cgttgatatc
    37861 aatcataaat gcatccgttc gtgggaccat gacttctcgg gcaactttcg tatcaagaga
    37921 aaaaacccct tggagcattt ctaattcttc attattcaat acgccttcgt tttcaagcat
    37981 ataacgcatt tcatctctgg tcatttttga atcttcatca tcaaaagtca tcggcgtgat
    38041 acgcgccaat aaacttgtgg aagcagaaag cagccagacg aagggcttag ctactacacc
    38101 aatcaagcgt atcagccctg aagtgaactt tgcgacttct tctgatttat ttaaagcaat
    38161 acgtttaggg tacaattctc caaaaacaat cgatacatag gtcaaaatag ccagcacaat
    38221 gatatttgca atattttttg ccgctgtgcc gccacctaat accggagcta accgttccga
    38281 taaagtatta gctagtgaag caccagacaa aatgttgacc aaagtgattc ctacttggat
    38341 tgtcgatagg aaattatttg gattctgcaa tatttttaaa agcttttgag atttcacatc
    38401 tccttcatca gctttttgct cgattcgatt cttattgatc gaaacaacag caatttcgga
    38461 agctgctaaa aaagcattga tcaatgtcaa aacgatcaat aataaaatct gcgctaacag
    38521 cgactgactc tcagggtcag cattcataat cgcattctct ccttataaaa ttaattttta
    38581 gtttacgata gaaaaaaacg tggcactata gccacgttaa aatggtatca caaagcaatt
    38641 ttctttgcaa taaaaacaag tgtactaaaa ctacctacga ggtcgtagca attttcttct
    38701 tgttttcatt ttgcttgtct tctttgacga ttttgattat ataggaaatg atcgtcttgc
    38761 agattgcgta aaaaggaaca cctaagaaga taccaagcaa tccggcaata tttccagcta
    38821 ctagaagaac gataatgatc gttaatggat ggattttcag tgatttccca attacattag
    38881 gataaatgat attcccatcc aactgttgga cgattagcac aaccacacaa caaagtaatg
    38941 cttttaccgg atcattgaag actgttacta gaaatgcagg tgctagtcct agataaggtc
    39001 ctaaatatgg aattaggttt gtcaatcccg caatgacccc aaataagaaa gcataatcca
    39061 caccaattac catatatcct aaaaatgtga aggtaccaac gaataaacat tcgattgctt
    39121 gtccgctaat gtaattagcc aatgttttat tcagttgccc caataactcc acaatttggt
    39181 ttcttctttt ttctgggaaa aactgttgga tgtttggcac tagtttttct ccgtctttca
    39241 acatatagaa caagatgaat ggtgctgtaa tgattactac ggttgccgaa gcgatcgttc
    39301 caacgatcga acctaaacta ttggatactc cactaaggaa ttgctgaatg attgtcccgt
    39361 aagaaatgtc taattgctca aaatatttat tgatatctac ttccttgaac aaaggcaatt
    39421 cggctacctc ttttaaccag ctttctacct gtttgatgaa atcaggcata ttagatgcca
    39481 atgaggaaat ttgctgtact agacttggga tgacactaag taaaatccaa ataattgctg
    39541 caactaaaag gagcagcaca attgcgacag cccatattct tttgattttt gctttcatca
    39601 acagcttgac aataggattc aataaatagt aaagaaagcc tgcaatcagt acaggtgcaa
    39661 ataacgtgga aaaaaatgtc ccgatcggtt cgaaaataaa gtttatttct gatgaaatca
    39721 tgatcaatgc agctatgatc aataattcaa gcgaccaaaa cattagttta gactgtctaa
    39781 gtttttcaaa caatagattt cctcctttct ttcttactag tatatattat attcgttaaa
    39841 aattctttta ttcttttttt atttttgaaa acttgccata ctttttattt gttttatttt
    39901 ccagtatact atacgaaagg aaggtggcta gaccatgaaa gttgtacaaa caaaagatac
    39961 aatgagcaat atttacttag atgctgtacg gatcaggcat caagtttttg tagtcgaaca
    40021 gggtgtgcct ttgtctcgag aaatagacaa agatgaagcc cattgtatcc acttcgtcct
    40081 gtactcagat aaaaaagaac cgcaaggaac tgtacgtctt ttgcctttag aaaacggaaa
    40141 aatgaaatta cagcggatgg cgattctttc tgaatacaga caccaagggt taggaaaaat
    40201 attgattgaa gaagcagaaa actttgctaa gaatcaaggc tataatacga ttttattagg
    40261 ggcacagtcc acagctgaaa ctttttacga aaaactagga tatacagctt acggcgatcc
    40321 ttttgaagat gctggcatgc ctcatattta tatgaaaaag actttataaa aatttatttc
    40381 gaaaaaagca aaaaacagca agcttttgag aaaaatctct cactggctta ctgttctttt
    40441 ttgtgtttac ttacgcgaca attgcttgta acggttatac caaatatcaa tatagccttc
    40501 cgagaacggg ccatctccat tattgatcca gtcaaccaga atcttcacat tttcttttag
    40561 gatgaagtca atatcgttcg ggtaattcat cattttgctg tgcatctcat attcatcgac
    40621 atccaatagt cgtttctcgc cgtcaggaaa taccttgata tccaagtcat agtcgatata
    40681 tttcaaggcc tcatcgtcca gcaaaaaagg tgaagctaga ttacaataat aggaaacccc
    40741 cttttctctg atcattgcta ttacattgaa ccagtatttt ttatgaaaat aaacaatcgc
    40801 tggttcgcgc gttacccatc ggcgtccatc agattcagtg actaatgtgt gatcattcac
    40861 gccgatcata gagtgttcgc ttgtttttaa taccatggta tctcgccacg ttcgatgcaa
    40921 tttgccgtcg tgcttgtaac tttggatcgt cacaaactct ccttcttttg gaactcccat
    40981 agcaaccctt ccttaagcag cattttgtgc tttgtgtttg ggtgttcatt acaccgacat
    41041 cataattatt atatcaataa aaatgagctt tgcctagaaa ggattcctat tgtttcgatt
    41101 tttctctaac tgatctacca gtttcatttg gaccttagga aaaacgaccg aatcaaatgc
    41161 atcaggcttc aaccacttcg aagttttgtt ctcggtaaat tcttgttctg ctccctcggt
    41221 tgcccgtccg taaaaaagga gaacatgcca tttcagatga ctaaaaatat gagtaacttc
    41281 tcctaaatgt cgtgtctgcc aaacaaagag ttcctgcttt tcaaatggga gattttgctc
    41341 ttcttctgct actaggtcat caaacagatc gatttctggc tttgtttccc attctttttt
    41401 caatcgctca tactcctctt gtgtcacttc catcattgga aatgtccaca tattcgccag
    41461 caatttttgg ctatctcttt cttcaaaata atacgctcca gaatgatttt gaagagctgc
    41521 actgatataa taaacgtctt ttggctttgc tttttttgtt tttacaggaa aactcgtttg
    41581 gattcctcgt ttgttagcta aacaaaaggc ttggatcgga caagtctcac actttggaga
    41641 agttggtgta cagatagctg aacctagatc catcattgct tggttgaatt cacctggatg
    41701 cttttcatca atgattttcc gcatcgcttc atcaaagatt ttcctgctag aagcttttgc
    41761 gatgtctgct tcaatgcaaa acaatctgct gactactcgc atcacgttgc cgtcaactgc
    41821 aggttctgga agtccaaatg cgatacttgc aatcgcgcct gtcgtatatg gtcctattcc
    41881 cttcaatgag ctaatttctt caggcgtttg cggcatttcc ccatcaaatt ctgacatgat
    41941 ctgtttagca gcagcttgga tgttccgggc tcttgagtaa taaccaaggc cctcccatgc
    42001 ttttaaaagc ttttcttctg gagcatttgc tagctcttca attgtaggaa accattccat
    42061 gaaacgataa aaataatcga tcactgtgtc tactctggtt tgctgaagca tgatctcaga
    42121 gatccagata cgataaggat cacgattata gcgccaaggc aggtttcttt tttcttgttc
    42181 ataccattga atgaactgat cttgaaattc ttttgtttct ttatctgtcc atttttccca
    42241 ttctttattc actttcctct tccttttccg taatgaatcg ctggatcata tccaaatcaa
    42301 atcctttttg atataagctt tgctttactt ttagatttct ttttttaggt tcaaacctta
    42361 aatttcttcg ccatagttta tctccttgtt tgactaaata atcatattct atttcttgat
    42421 ctgcttcttg cggaagatca gctatcgctt gttggatcac ttcttgagaa aagcctttcg
    42481 tcatcaatgt ttgttggatt tttctcaata attctttttg gctttttccg tgattttttc
    42541 caaacgcttt ttcggctgtc tgatgtgcat tttgaacttg gtcttcaaat gtatattggc
    42601 tgagcgcttg ttcaatgatt tcaggtttca aacctttttg ctgcatctgc tgcgctaatt
    42661 tctttggtcc tttgtcactt aagcgcatat tcgtgcgcac ataactttcc ccatagacca
    42721 aatcatcgac aaggtccaat tcttttaagc gggctacgat tttatttcga tcttcttgaa
    42781 ggatttcctt ttcttttaag tatgttcgga tttctttttc cgatcgcaac tgataactta
    42841 agtaattcat tgctaggtga aaaccgaaat cagctccgct actcttcttg atctcttgga
    42901 tagtttcttc gtctaattcc cgtcctttta ataatcgata gcgtactaat acatcttcag
    42961 atacttgtaa agcttctcct tcagataaat ctacgcgata gaaagggcct ttgcctttac
    43021 tgattctcgt aacggttaac ataaacatcc tcctcgaaca tatattctct atcataccac
    43081 agaaaatccc cgtaatcagg tattatatgt tagaataaac cacagaaaaa agaaaaaggg
    43141 agatacttat ggcagaaaca attgtcaaaa ctggacaaac ggttcctttg aaaatcaagc
    43201 gtttaggcat aaatggtgaa ggaatcggtt atttcaaacg gttgatcata tttgttccat
    43261 atgcactacc aaaagaagaa gtactagtga aaatcacgaa agcaactcct cgctatgcag
    43321 aaggagaatt aataaaagtc aaaaaaacaa gcaaagatcg cgtagtggca ccatgtcctg
    43381 tttactatga atgcggtggc tgtcaattac aacacttagc ttatcaagct caattggatt
    43441 ttaaaaagga tctgcttttg caagcattgg aaaaattcaa accagcaggc tttcgatctt
    43501 atcaactttt gccgacgatc gggatggatg agccttggca ttatagaaac aaagcacaat
    43561 ttcagttacg aaaaaataag cagactcaaa aaattgaagc tggtttatac gaagcaaact
    43621 ctcatcagtt agtccctata acagactgct tggttcaaga acctcgaaca caaaaagtaa
    43681 tgaatactgt tgttcaacta ttgaataaat ttgatgcacc catctatgat gaacggacaa
    43741 acagtggaat cttccgcaca atcatggtta gaatcggtgt taaaactggg gagttacaag
    43801 ttgtttttat tactcgcagt aaaaaattcc cgcaaaaaaa cgcaatgatc cgtgagatca
    43861 atgaacgact gcccgaagtt gtttcaatca tgcaaaatgt ccaggcacaa aaaacgtctc
    43921 tcgtgatggg ggatgaaacg atccacttat ggggaaaaga agccattgaa gaacaaatca
    43981 atgaagtgac tttcgatctt tctcctcgtg ccttctttca actcaatcct cagcagaccg
    44041 aattgcttta tggcgaagga atcaaagcat tagatgtcca gcctaatgaa acgatcgtgg
    44101 atgcttattg cggagttggg acgatcggct taagtgtagc aaaacaagcc aaagaagtac
    44161 ggggaatgga taccgttcct caagcaatcg ctgatgcaaa aaaaaatgcg gaaagattag
    44221 gatatcacaa cactcgatat gaagtcggga cagcagagca agttctgcct aaatggttga
    44281 atgaaggttt tcagcctgat ggtatcatcg tagatccacc acgtacgggt ttggataacg
    44341 cattgatcca atcattattg aaataccctc caaaaaaact tgtttatatc tcctgtaatg
    44401 tttctacact tgccagagat ctggttaatt taagtaaaaa gttcaagatt gaatatttac
    44461 agtccgtcga catgtttcct cagactgcac gttgtgaagt tgtcgtgaag atgacgagac
    44521 tcgctgacta aatgaaagag gttgtgaaaa agtctgccct gtatcaagta ataagaacag
    44581 ccaaacaaaa atagctcttc atgttttatg aatactgtac ttgtgaccga agagttaaca
    44641 ggaggacact atttatttaa aaaaagggtt gtgacatagt ttttgtcaca gccctttttg
    44701 attattattg gatattcacg tctatcactt gataaaatgc atttgtcgta tcgctgatat
    44761 tccatactgc taaaatcaca ttatatcctt ttcgatcctg cggaagtgtg atcgtttggt
    44821 tgactgtttt tggtggaaca gttgctttgt cgtctatttt tgtgatcaat tcaaaatcac
    44881 taaatttcaa aggttgatta ggattccaag ttggtttggt aatgtagtaa tcccaagtac
    44941 ttgtccgatg ttgtgctgtt aaattccaag taatatttaa tgttcctgga ttaaccatgt
    45001 ttttatgcca tctgttagat gtctgttcat ctaaaggctc aaagccgctg actcctgcac
    45061 tagcaatttt tccatcaatg aatgtatttt tggtagcttc gatactttgc ggttcccatt
    45121 gtgctcttcc gacattttga tttaagtttc ctgctgctga tgttcctagg tatgcacggc
    45181 ttcctggaga agtaatataa ccatgcgcaa aacctggaat gctaaaaccg aacaacccta
    45241 aactaactaa cccaataaac aataacgtac taatcttttt catgtagaaa cctccttcat
    45301 ttgataacca cattgtaaac gctttattgt attaacacaa acattatgct tttataattt
    45361 tatgttgaag taaaaaaggt gaaaaaagta agatgcagat tataacagaa gtagacgaga
    45421 aaagtacaaa tagaaaacat gagaatcaaa tcatatgatc tttttcaaaa acatcattca
    45481 tataaacaaa tgttcaactt tttaataaca acaattatca atttttttct tacttcacaa
    45541 actaaataca ggtcttgctg tgagccttca tggtaaacta atattataga aaggagttag
    45601 taaaatgaag atgataaaag atattcgttt ttgggtttgt gttataggaa ttgtcatatt
    45661 aggcttttta tcagggttgc ttagcggaaa tcccggaaaa tattactatt ctttgcaact
    45721 tccaccattt gcaccaccta gctggatatt tgggccgatg tggaccttac tgtatatatt
    45781 gatgggtatt tctctttatt tgttacttaa tcacaacaac aaaaaacagc gaaacaatct
    45841 tgtcggtctt tttgtgattc agttcatttt taattttata tggtctgctc tattttttaa
    45901 tttaagaaat attttcattg cagcaatcga tattacactt ttagttattt tcttgtcagt
    45961 gcttatgtat cagttgtggc tgcatcatcg cctggcaatg tggctcatga ttccttatta
    46021 tttatgggta ctattcgcaa ctctattgaa ttattcaatt tattttttaa actaagcgct
    46081 aaaaagagac gtcctgtaat ttaacacata gaaaaagtgc cacctaagtt agatt
//
LOCUS       DADQCX010000011        45507 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.011, whole genome shotgun sequence.
ACCESSION   DADQCX010000011 DADQCX010000000
VERSION     DADQCX010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.011"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            110..2707
                     /gene="adhE"
                     /locus_tag="J8R83_000569"
                     /gene_synonym="adhC"
     CDS             110..2707
                     /gene="adhE"
                     /locus_tag="J8R83_000569"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAZ9573726.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            2936..4042
                     /locus_tag="J8R83_000570"
     CDS             2936..4042
                     /locus_tag="J8R83_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAZ9573727.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            4059..5087
                     /locus_tag="J8R83_000571"
     CDS             4059..5087
                     /locus_tag="J8R83_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAZ9573728.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            5093..5572
                     /locus_tag="J8R83_000572"
     CDS             5093..5572
                     /locus_tag="J8R83_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAZ9573729.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            5588..6883
                     /locus_tag="J8R83_000573"
     CDS             5588..6883
                     /locus_tag="J8R83_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAZ9573730.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            6894..7718
                     /locus_tag="J8R83_000574"
     CDS             6894..7718
                     /locus_tag="J8R83_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9573731.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            7883..8782
                     /locus_tag="J8R83_000575"
     CDS             7883..8782
                     /locus_tag="J8R83_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9573732.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(8908..9777)
                     /locus_tag="J8R83_000576"
     CDS             complement(8908..9777)
                     /locus_tag="J8R83_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9573733.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            9930..11390
                     /gene="rhaB"
                     /locus_tag="J8R83_000577"
     CDS             9930..11390
                     /gene="rhaB"
                     /locus_tag="J8R83_000577"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAZ9573734.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            11387..12643
                     /gene="rhaA"
                     /locus_tag="J8R83_000578"
     CDS             11387..12643
                     /gene="rhaA"
                     /locus_tag="J8R83_000578"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAZ9573735.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            12657..13502
                     /gene="rhaD"
                     /locus_tag="J8R83_000579"
     CDS             12657..13502
                     /gene="rhaD"
                     /locus_tag="J8R83_000579"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAZ9573736.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            13504..13815
                     /gene="rhaM"
                     /locus_tag="J8R83_000580"
     CDS             13504..13815
                     /gene="rhaM"
                     /locus_tag="J8R83_000580"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAZ9573737.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            13897..15048
                     /gene="fucO"
                     /locus_tag="J8R83_000581"
     CDS             13897..15048
                     /gene="fucO"
                     /locus_tag="J8R83_000581"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAZ9573738.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            15175..15933
                     /locus_tag="J8R83_000582"
     CDS             15175..15933
                     /locus_tag="J8R83_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAZ9573739.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            16033..16677
                     /locus_tag="J8R83_000583"
     CDS             16033..16677
                     /locus_tag="J8R83_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAZ9573740.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            16684..17691
                     /locus_tag="J8R83_000584"
     CDS             16684..17691
                     /locus_tag="J8R83_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAZ9573741.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            17707..18549
                     /gene="kduI"
                     /locus_tag="J8R83_000585"
     CDS             17707..18549
                     /gene="kduI"
                     /locus_tag="J8R83_000585"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAZ9573742.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            18569..19372
                     /locus_tag="J8R83_000586"
     CDS             18569..19372
                     /locus_tag="J8R83_000586"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAZ9573743.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(19621..20685)
                     /locus_tag="J8R83_000587"
     CDS             complement(19621..20685)
                     /locus_tag="J8R83_000587"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAZ9573744.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(20682..21767)
                     /locus_tag="J8R83_000588"
     CDS             complement(20682..21767)
                     /locus_tag="J8R83_000588"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAZ9573745.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(21780..22757)
                     /gene="mvaD"
                     /locus_tag="J8R83_000589"
     CDS             complement(21780..22757)
                     /gene="mvaD"
                     /locus_tag="J8R83_000589"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAZ9573746.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(22750..23694)
                     /gene="mvk"
                     /locus_tag="J8R83_000590"
     CDS             complement(22750..23694)
                     /gene="mvk"
                     /locus_tag="J8R83_000590"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAZ9573747.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            24016..24669
                     /locus_tag="J8R83_000591"
     CDS             24016..24669
                     /locus_tag="J8R83_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAZ9573748.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            24754..25659
                     /locus_tag="J8R83_000592"
     CDS             24754..25659
                     /locus_tag="J8R83_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAZ9573749.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(25661..26293)
                     /locus_tag="J8R83_000593"
     CDS             complement(25661..26293)
                     /locus_tag="J8R83_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAZ9573750.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            26613..27137
                     /gene="infC"
                     /locus_tag="J8R83_000594"
     CDS             26613..27137
                     /gene="infC"
                     /locus_tag="J8R83_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAZ9573751.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            27209..27409
                     /gene="rpmI"
                     /locus_tag="J8R83_000595"
     CDS             27209..27409
                     /gene="rpmI"
                     /locus_tag="J8R83_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAZ9573752.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            27462..27821
                     /gene="rplT"
                     /locus_tag="J8R83_000596"
     CDS             27462..27821
                     /gene="rplT"
                     /locus_tag="J8R83_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAZ9573753.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            28073..29410
                     /locus_tag="J8R83_000597"
     CDS             28073..29410
                     /locus_tag="J8R83_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAZ9573754.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            29458..31587
                     /locus_tag="J8R83_000598"
     CDS             29458..31587
                     /locus_tag="J8R83_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAZ9573755.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            31562..32251
                     /locus_tag="J8R83_000599"
     CDS             31562..32251
                     /locus_tag="J8R83_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573756.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(32659..33346)
                     /locus_tag="J8R83_000600"
                     /pseudo
     CDS             complement(32659..33346)
                     /locus_tag="J8R83_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(33482..33676)
                     /locus_tag="J8R83_000601"
     CDS             complement(33482..33676)
                     /locus_tag="J8R83_000601"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573757.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(33726..34166)
                     /locus_tag="J8R83_000602"
     CDS             complement(33726..34166)
                     /locus_tag="J8R83_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAZ9573758.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(34170..35015)
                     /locus_tag="J8R83_000603"
     CDS             complement(34170..35015)
                     /locus_tag="J8R83_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAZ9573759.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            35164..36582
                     /gene="pepV"
                     /locus_tag="J8R83_000604"
     CDS             35164..36582
                     /gene="pepV"
                     /locus_tag="J8R83_000604"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAZ9573760.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(36639..37586)
                     /locus_tag="J8R83_000605"
     CDS             complement(36639..37586)
                     /locus_tag="J8R83_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9573761.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(37809..38159)
                     /locus_tag="J8R83_000606"
     CDS             complement(37809..38159)
                     /locus_tag="J8R83_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9573762.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            38359..39438
                     /gene="pepA"
                     /locus_tag="J8R83_000607"
     CDS             38359..39438
                     /gene="pepA"
                     /locus_tag="J8R83_000607"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAZ9573763.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            39582..39902
                     /locus_tag="J8R83_000608"
     CDS             39582..39902
                     /locus_tag="J8R83_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAZ9573764.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            39924..40388
                     /locus_tag="J8R83_000609"
     CDS             39924..40388
                     /locus_tag="J8R83_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9573765.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            40593..41198
                     /locus_tag="J8R83_000610"
     CDS             40593..41198
                     /locus_tag="J8R83_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAZ9573766.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(41237..42526)
                     /locus_tag="J8R83_000611"
     CDS             complement(41237..42526)
                     /locus_tag="J8R83_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAZ9573767.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42954..43433
                     /gene="rlmH"
                     /locus_tag="J8R83_000612"
     CDS             42954..43433
                     /gene="rlmH"
                     /locus_tag="J8R83_000612"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAZ9573768.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            43636..44186
                     /locus_tag="J8R83_000613"
                     /pseudo
     CDS             43636..44186
                     /locus_tag="J8R83_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            44257..45426
                     /locus_tag="J8R83_000614"
     CDS             44257..45426
                     /locus_tag="J8R83_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HAZ9573769.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT        14520 a         8211 c         9655 g        13121 t
ORIGIN      
        1 aataactgtg aaaaaaatca caaaaaagtg tttacataga aaaataaata ttgtatgata
       61 tacatgtgaa ttatttaaca aataaccatg acccattagg aggataatga tggctaaagt
      121 aatagaaaaa gaaaaaacga agacaattga cgtacaagca atgattgatg atttggcaga
      181 aaaagcaaat gcagcattga aagaaatgga aagctttgat caagaaaaag tagaccatat
      241 cgtgcatgaa atggcaatgg cagctttgga tcaacatatg ccattagcga agatggctgt
      301 agaggaaaca ggccgcggtg tttacgaaga taaagcaatc aaaaatatgt atgcgtccga
      361 atatatttgg cataatatca aacatgataa aacagttggt gtgatcaatg aagatgtcca
      421 aaaagggttg attgaaattg ctgaaccagt cggtgtggtt tgcggagtaa ctccaacaac
      481 gaatccgact tccacaacga ttttcaaatc aatgatcgcg ttgaaaacaa gaaatccaat
      541 cgtttttgct ttccatccaa gtgcccaaaa atcttctgca gaagcagcac gagtggtacg
      601 tgatgctgct atcgctgccg gagctcctga aaattgtatc caatggatcg aacatccttc
      661 gatcgaagcg acttctatgc taatgaacca tccaggtatc gcgatcgtct tagcgacagg
      721 tggagctgga atggtcaagt ctgcttactc tacaggaaaa ccagctttag gtgtaggtcc
      781 aggtaacgta ccagcttata ttgaaaaaac agcaaaaatt aaacgtgcag tgaacgattt
      841 gatcgtttcg aaaacatttg ataatggaat gatttgtgct tctgaacaag ctgtgatcgt
      901 ggataaagaa atctatgcag cagtaaaagc agaattccaa gcacaccaag tttatatcgt
      961 aaaaccagat gaattgcaaa aattagaaga tgcagtgatg aacgaaggaa aatatgcggt
     1021 caatccatca atcgttggac attctgcgat ggaaatcgca aaattggcag gaatcagtgt
     1081 accaaaagga acgaaaatgc tgattgctga attggaaggc gtaggcccag attatccgct
     1141 atcaagagaa aaactttctc cagttcttgc catgatcaaa gctaacaaca cggaccatgc
     1201 gtttgatttg tgtgaaggta tgttgaatct tggaggatta ggacatacag cagttatcca
     1261 ttcagaaaac gaagagttgc atgtcaaatt cggtcttcga atgaaagctt gtcgtatttt
     1321 agtgaataca ccatctgcag aaggcggcat cggtgatatc tataacgaaa tgattccgtc
     1381 attgactttg ggatgcggtt cttatggtaa gaactctgtt tctcgtaacg tctctgctgt
     1441 aaacttaatc aatgtcaaaa ctgtagcgaa acggagaaat aacatgcaat ggttcaaatt
     1501 accgccaaaa atcttctttg aaaagaactc tctattgtac ttagagaaaa tggaaaacgt
     1561 tgaacgtgtc atgatcgttt gtgaccctgg tatggtccaa ttcggttact gcgatacagt
     1621 tcgtgaagta ttggcacgac gtaaaaatga tgtgaagatc gaagtcttct cagatgttga
     1681 accgaaccca tcgacaaata ccgtatacgc aggaacgaaa ctgatggcag acttcaagcc
     1741 agatacagta atcgctcttg gaggcggttc tgcaatggac gcagctaagg gaatgtggat
     1801 gttctatgaa cacccagaca catctttctt tggtgcaaaa caaaaattct tggatatccg
     1861 taaacggaca tataagatcg acaaaccaga aaaaacacaa ttcgtatgta tcccgacaac
     1921 atcagggact ggttctgaag taacgccatt tgcggtcatc actgacagtg aaacacatgt
     1981 gaaatatccg ttagcagatt atgcattgac gccagatgtc gcaatcgtcg atcctcaatt
     2041 cgtcatgtca gttccagcat ctgtcacagc agataccggg atggatgtgt taacacatgc
     2101 aatcgaatcc tatgtttcag tcatggcttc agattataca cgtggattga gcctacaagc
     2161 aatcaagtta gtctttgact atttagaaaa atcagtaaaa acacctgata tggaatcacg
     2221 tgaaaaaatg cacaacgctt ctacaatggc tggtatggcg tttgctaacg cattcctagg
     2281 tatttgtcac tcagtcgcac ataaaatcgg cggggaatac gggatccctc atggacggac
     2341 aaatgcgatt cttttaccgc atattatccg ctataatgca aaagatccac aaaaacatgc
     2401 gatgttccct aaatatgact atttccgtgc agatacagat tacgcagata tcgcaaaatt
     2461 cttaggtctg aaaggcgaaa caacagagga attagtcgaa gctttagcaa cggctgttta
     2521 tgaattagga aaatctgtcg gcatcaacat gagtctaaaa gctcaaggag tcacacaaga
     2581 aacactagat acaaccgtag accgtatggc tgaattagct tacgaagacc aatgtacgac
     2641 agctaatccg aaagaaccat tgatctctga attgaaacag atcatcattg atgcttacaa
     2701 cggataagca aaagaaagcg tagaaaaaag ataagaaaat agatgaaaaa gaacttggaa
     2761 aacgttgttt ctccaagttc tttttttaat ttccaagtaa ctgaaagtta cttttgttat
     2821 ttaacattta ggtcaatttt agacagtttt tgttcaaaaa gcgatattta tagtggacgg
     2881 tattactgct atattaagga tataaaatga aagcgtttaa aaaggtggcg taaagatgat
     2941 tattaaagaa gagatttttg tacctaaaga attagtgaaa gaaaaaattg acctgctcgt
     3001 tgaaaacctg acaacgatca aagacgataa tggtgaattt ttgttggact ttgatggact
     3061 gaaagtagat gacaaaagct ggacagtgtg gaattggcca caaggtgtcg gtctatatgg
     3121 tatttataaa aattaccaga tgacaaaaaa tcctcgcgct tatcaagtgg tcaatgaatg
     3181 gtttgaggat cgtatggaag aaggcgctcc gcccaaaaac gtcaatacaa tggcaccgct
     3241 attgactatg gcttacttgt atgaagacac gaaagattca cgctatttgc cttatttaga
     3301 acaatgggca gaatgggtca tgaatgacat gcctcggaca aatgaagacg ggttacagca
     3361 tgccacatat ggaccggaaa ataagaatca gttgtgggac gatacattga tgatgacagt
     3421 gcttcctttg gcaaaaatcg ggaaactgtt gaatcgccca gaatatttag aagaagctcg
     3481 ttaccagttt atgatccata tcaaatactt gatggataaa cgaacaggat tgtggtatca
     3541 cggctggacg tttgaaggaa atcataacta tgccgaagca ttttgggctc gtggaaactg
     3601 ctggttgacg attgctattc cagagatcat tgaaatctta gaattatcga aagaagatgc
     3661 attgcgcaaa ttattgatcg aaacacttga agcacaagtg cgtgcattaa aaacttatca
     3721 gtctgaaagc ggtttatggc atacgttgtt ggatgatcct tcttcttacg tagaatcttc
     3781 tgcaactgca ggatttgctt acggtatttt gaaagcggtc cataaacgtt atttaccaca
     3841 agaatataaa gaagtcgctt atcgtgctat ccaaggattg cttgaacaaa tcgatgaaaa
     3901 aggagaagtt caaaacgttt caatcgggac aggaatgggg gacagtttag atttttatcg
     3961 gaatatcgga atcacagcaa tgccttatgg acagtcgtta acggtgcttt gtttgacaga
     4021 attgctcgtc tcttattgtt aaaagaaagg aaacccatat gaaaaaaaca tcactgctgt
     4081 ttgcagcaag ttcgcttagc ctaggtctgc taggtctaag cggctgcgga aataattcta
     4141 gtgtggcaac tgtcgcagat gcagatgtaa atgagatagt taccttgcgc tttgcttatg
     4201 caagcaacag ccagccagta attgatgcaa tgaatgaatt tgggcgttta gtaaaagaaa
     4261 aaacagatgg ttccgtacag atccagtatt tcccagatgg acaactgggt ggagaacgtg
     4321 aactgatcga attgacacag tcaggagcag tagatttcac aaaagtaagt gcctcagcgt
     4381 tggaaagttt ctctaaagat tattcgattt tttcagttcc ttatctattc aatgatgaag
     4441 aacatttctt taaggtgatg gataatgaag aaataatgga gccaatctac caatcgacca
     4501 aaaatttagg atttaccgga ttgacctatt atgattctgg tcagcgcagc ttttatatgg
     4561 tagacggtcc gatccatacg ccggaagatt tgaagggaaa gaagatccgt gtgatgcaaa
     4621 gcgaaaccgc tatcaaaatg gtagagcttt taggcggttc gcccgtacct atgggaagtg
     4681 atgaagtgta cacgtctctt caatccaatt tgatcaacgg atcagaaaac aatgaatttg
     4741 tcttgtatac agctggacat ggtggtgtgg ctaaatacta ttcctatgat gagcatacac
     4801 gtgtgccaga tatcatcatc atgaatgatg ccatcaaaga acagctaact gatgagcagg
     4861 aaaaagccat tgaagaagca gcgaaagaat caacggtttt tgaaattgaa gcttttgcaa
     4921 aagcaattga agaagaaaaa gctttagcac aagaagaaca tggagtccaa ttcaatgatg
     4981 tagataatac accgtttcga gaggcagttg ccccacttca tgatatattc aaaaacgatc
     5041 ctacctacaa agacctttat caaaagatcc aagagcaagg agcgtagctg tgatgaaaat
     5101 gattttaaac aaggtattag agatcctggg agctgttttg cttgttggga tggtcgctgt
     5161 tgttttatgg caagtatttt ccagaacggt tttaggaaat ccaaatacgg tcacggaaga
     5221 gcttgttcga ttcggtcttg tctggtttgc catgttgtct tccgcgtatg ttgtgggaca
     5281 aaaagcacat ttagccgtaa cggttttaag tgaaaaatta actggcaaaa aaagtaaaat
     5341 tttagaagtt gttgttcaaa gtttatttct ggtatttgct gcgatgatca tggtgtatgg
     5401 cggatggaat gctgtcacat tgacaatggg gcagatctcg ccttctttaa gtattcctat
     5461 gggatatgtt tatctgtcag tacctgtatc gggggtactc atcattatct atagcctgat
     5521 caatctaatc gatacattaa gcaacaagcc agcaattcaa gaaaaaatat aaaaatggag
     5581 gaataaaatg gcaatagaag ccggattagt gttatttttt gtatttgttg tgttgcttgt
     5641 attagggatg ccgattgcta taagtattgc attctcatcg atgatgactt tattgttagt
     5701 tataccgttt gatgtttctg cttttagttc agctcaaaaa atggtgggaa gtatcaatag
     5761 tttttcgctg atcgctattc cgtttttcgt tctctcgggc attatcatga ataatggagg
     5821 gatagctaag aaactagtgg attttgcgat gttgttcgtc gggcgcgtgc cgggggcttt
     5881 ggctcatacg aatgtgttag ggaatgcttt atttggttcc atctctagct cggccattgc
     5941 cgcttctacc gcgattggcg gagtgttgat ccctcagcaa gtggaagaag gatatgaccg
     6001 gaagtttgcg acagcggtca atatcgcgtc agctccgaca ggtatggtca ttcctccaag
     6061 tactgctttt atcatgtatt cacttgttgc tggtggtgct tcgatctctg ctttgtttat
     6121 gggaggttat ctcgtaggcg ctttgtgggc gctaggaatc atgctagtag cattcatcgt
     6181 tgctaaaaag aataaatacc ctgttgtcga aaaaggacag atggctcatg ctggaaaaat
     6241 aataaaagag gcgattccta gccttctatt gattgtcatc attatcggtg gtatcttgac
     6301 ggggatattt acagcagtag aagcttcagc gatagctgtc atttactccc tgttgattgc
     6361 tatgttttac tataaaacgg taaaactaaa agatatacct aatatgttgt ttcaatcagt
     6421 agcaatgtca gggacgatca tgttcttatt ggctacttct tccatgatgt ctttcgccat
     6481 ggcgtttacc ggtattcctc aggcaattag ttcgttgatt atgggcgtaa cggataataa
     6541 atttattatt ctgttattag tcaatcttgt gttattactg gtgggtatgt ttatggatgt
     6601 ggcgcctgct atcttgattt ttacaccaat atttttacca atcgtcacaa gtgtaggggt
     6661 tgatcctgta cattacgggt tgttttcaat catgaatctg tgtgtaggct ccatcacgcc
     6721 gccagtaggt acaggactat atgtcggtgc aagtgtagga ggcgtaaaag cagaggcaat
     6781 gctgaaaccg cttcttcctt tttatggggt tatcttagtc gtcttgtttt tgattactta
     6841 cttcccgcaa atcgtcatgt ggctacccaa tatgctgagt taggagaata gttatgttga
     6901 acattacaat tagaggacat gatctttccg aagtccaaac gatagaagat cttgcagaaa
     6961 aaacaaaaga acaagggatt catacactgc agctcgcctt aggtctttcg tttcctgaaa
     7021 taccttctgg cgcaaatgag atcaattctg ggatgggaaa ttatgtcaaa cgagttttag
     7081 aaaagcaaga agtgaccgta ggaattttaa gttgctatat caatatgatt catccagatt
     7141 taacgatacg acaagagttg ctgacaaagt tcgagcagta tcttcgctat gcttcttcct
     7201 ttggtgcgtc gatggttgct tcggaaactg gatgtgtttt gccggaaatc caatatacgg
     7261 aagaaaattt cacagatgaa gcatttgctg aagctgtgtc cgttatccgt cgcttggtaa
     7321 aagctggaga aaaataccaa atgatggtgg ggatagaacc aggtttgaat catccggtgt
     7381 attctttagc aagggtagag cagctgatcc aagcagtaga ttcggactat ctaggaatca
     7441 ttttagatcc gaccaatttg atcacaagta gtgattatca agaacaagtc caattggtag
     7501 aagaagcttt tgaacgtttt ggtgaaaaga tatgtgcggt tcatttgaaa gattttcgtg
     7561 tcgaacagga aaaaatcgtg ccggtaaatt tgggagacgg tgtgatcgag tacacaaaaa
     7621 tcaaagaaat catcatgaag aatcgtccgt acctgtatgt ggttcttgaa gaaacaaaag
     7681 atgatgggat tcgttatgga agaagtcttc ttgaataatg taaagaagac gttggttaac
     7741 taatatttag aatggagggg gcggggctag aagatgccac gtctcttctt ttttataaga
     7801 gtatataaaa gcagctcttt ttgattacaa aaaacgtggt ataataaaat tgtgcataag
     7861 tgaacaaaag gaggtgcggc acatgctcca aaagaaaatc agcggtgaac aagtcaatac
     7921 gatggtttct gatcagtatg aaatctatca tgtcaaagat gtcgtcagcc aaaataaaac
     7981 gatctatcat catcatgatt tctatgagat ccatgctaca ttaaagggag aagcgacttt
     8041 ttatttgaac ggacgacaat ttacgatcaa agcaggaagt gtgctgctca tccattccaa
     8101 tgatttgcat cgtatcgtcc gccaatcttc agatgtattc gagcgtgtct atatctttgt
     8161 caccccttct tttctagaaa gtcgttccac gccatggtct aatctatcgg cttgttttca
     8221 accaatggga gagaagagga gtcgtgtatt gcaaatagaa caggaagtat tgaagcaaaa
     8281 attatcattt atcgaccatc ctcctgataa aaaaatttac ggtgaagaca taaaatatga
     8341 acaagctctg gtagaatact tgatttttct caatcaagtt gtacaaaaag aagagagtgc
     8401 gcaagaacag aatgctgtag ttcctaatga gcgtgtggaa caaatgttac aatatatctc
     8461 aaaaaattta tctcatccgc tttctttaga ggaaatggaa aagcagtttt ttgtcagcaa
     8521 ataccatatc acacgagaat ttaaaaagta cactggattt acgtttcatc agtatgtaat
     8581 gaagaaaaag ctgatctatg ccaagcactt gttgcgagaa taccgcagct ctagtgctgt
     8641 atatagtaaa agtggttttt cttcttatcc gcattttctg aaagcattca agagagagtt
     8701 cggcataacg cctaaagaat ttttgaaacg tgatacacag aaacagttgg ttcattatga
     8761 acattttgaa gatgaacaat gagaatgatc actaaaaaat aaccgcagta gctgctgttg
     8821 tttacataga agcagaaact gcggttattt tatttttatc tatatatttc aaaatatttt
     8881 gaaaaaatga cgtacatatt atatgaatca gctgaattta cgaaagtctc tcggcgatag
     8941 tcctgttttt gctttgaaca ggcggctaaa gtaagcaaaa ttctcaatcc ctatttcttc
     9001 ggaaatcatt cgaaccgtaa attctgtata ccgaagaagg tctttagcgt aagaaagttt
     9061 tttgctgatc aaataatcga ttggtggaga accgataaat ttggaaaaat ctttgctcag
     9121 ctgatattta ttcaataaga attgttgttc taattgatca agtgtaatcg tttctttgaa
     9181 atgttcgtct aagtattgct tcagtttgta aacgtaggcg ggaatatcct cttcttcgaa
     9241 atctagctga tacttttgca aaatcagttc attcagcaac tcgtggatag ctacagagga
     9301 ctggaaatcg gtacgggcat tcgtgccttg ttgcatgtgg atcaattctg tgatcaaatg
     9361 gtggatcttg ttttctgatg gatctcctgt tgaatggaag gtgttatggc cgtcttttgt
     9421 gaactcctga taaaatgatt ggacgttctg accattcaaa tggatccaat ccatttccca
     9481 tggttcttcg ctgatcgttt gataacgctg atattcttgg cagtcaataa aaaataagtc
     9541 tccagctttt agctgttgct gattatcatt atatgtaagc gaacctttgc cagacaaagt
     9601 aaactttatc aagtaagaag gtaaatgtgc tcgttcagta tagtaaggga ttggtgcttt
     9661 gaagtaaccg atttcttgga tataaaaaaa taaattcctg cttctttgtg taggcgtcaa
     9721 gatcactctt tttgagtctt ccgaccatga gtggttggct ttttcccagt aatccatgta
     9781 aacactccca acttgtcaag ataatgcaat tatataccaa aatagtgtga agcaaaatat
     9841 aagattctgt attatgatag cattgtcaat aaatgataac gctttattaa taaagtgcta
     9901 atcaacaata aagtaaaaga ggtggagaaa tgaatccaac atttgttgcc atcgatatcg
     9961 gtgcatcaag cggacgacta atgaaaagta cgagggatgc aaaaggttct ttgatcttgg
    10021 aagaagtaca ccggttcaaa aacggctttc ggaacaaaga cggtcacgat cgctggaaga
    10081 tcgattatct tatcaaagag attttgattg gatttgaaaa attaaagcag acagggattg
    10141 atcgcctttt tgcggggatc gatacatggg cagtcgatta ctgtctgatt gatgaacaag
    10201 gggatcggat aaatgatccg attgcttatc gggacaagcg taccaatgga gcagtagaac
    10261 agttttctga aatctattct ctagataagt tgtatgagca gacagggatt cagatccagc
    10321 ctttcaatac cttgttccaa ttgtttgctg aagaaaaaga aaatttggca aaagcacata
    10381 aattgttact gatacctgat tatttagggt atgtctttac tggtaacatg gtgacggaga
    10441 aaactaatgc atctactatg cagctgctga atgcagggac aaaagaatgg gaaatagaac
    10501 ttcttgaaaa aatcggtgtc tcgaaggaat tatttccacc attgacagag ccgggaacga
    10561 tactaggaga tctgcaaaaa gaacaatttt caaaatatga tttgccagat gtgaccttta
    10621 tcacagtagc aagtcatgat acggcgtcag ctgtattagg aacgccaggt caaggagaac
    10681 gttggggtta tatcagcagt gggacatggt cgcttttagg gattgaaaca aagatcgcca
    10741 atgtttctcg caatgctttt tctgaaaatt atacgaatga atggggtgcc cataacacgg
    10801 tgcgtttttt gaaaaacatc atggggatgt ggttgatcca ggaagttgcc cgaatgcaag
    10861 agtacgagta cagttatgcg gaattggcag agcttgctgc aaaagaaaaa ccgctgcagc
    10921 aagtgatgga aatcaatgac cctcgatttt tgaatccccc aaatatgata gaagagattc
    10981 agcaatactg ttttgaaaca gagcagccag tccctgtctc atcgggagct atcgctcgtt
    11041 gtgtgtatga taatcttgct ctttgttacg cacaagagct gatcaaagta gaacacttaa
    11101 ctggaacgaa attggaaaag ctgcacatcg tagggggcgg atcgaataat cgtctactga
    11161 atcaattgac agcagattat gccggaatca ttgtagaagc aggacctagt gaagccacag
    11221 caatcgggaa tgttgccatg caaatgctca gtacaggtca gttttcgaat atagaacaag
    11281 caagaaatgt aatcaaacag tcgtttccat gtgaaacttt ttacccagat gaaaataagc
    11341 aaaacacgat ggaatggtac gtgaataaaa tcaaaggagt aatcgtatga acacgattga
    11401 aagaaattac gaacaagcaa aagaaaaata tgcaactatc ggtgtagata cagatgctgt
    11461 actagaaaag atacaggaca tcaaaatttc tatgcattgc tggcaaggag atgatgtcaa
    11521 aggtttcttg acaccggatg gcgaattgac cggtggaatc atggcgacag ggaattttcc
    11581 aggagccgca cgaacacctg aagagcttag acaagatctg gagaaggctt attcgttgat
    11641 accgggcaaa cacaaattga accttcatgc tatctatttg gatacagaag aatctgtcga
    11701 tctaaatgaa attgagccga aacattttga aaaatgggta gagtgggcaa aaaaagaaga
    11761 aatcggtctt gacttcaatc cgactttctt ttcgcatcca atgatgaaag acggctttac
    11821 attggctcat ccagataaag aagttcgtga atactggatc gaacacggga aaagaagccg
    11881 caaaatcgcg gagtactttg ggaaagaaac tgggcaaaca agtatcaata acttttgggt
    11941 acctgatggg atgaaagata atccgattga tcgttttacc ccacgggaac gtttaatgga
    12001 atcactcgat gaaattttta cagaagagtt agatgaacgg tatgtacaag atgcagtaga
    12061 aagcaaacta tttggtttag gcgctgaagc ttatacagtc ggttcccatg aattttatat
    12121 gggttacggg ttgactcgtg acaaacttgt ttgtctagat gctggacatt ttcatccaac
    12181 agaagtgatt tccaataaat tatcttcatt agctttattc agcaaaggaa tcatgttgca
    12241 tgtttcccgt ccagtgcgtt gggattcaga ccatgtggtt ttgatggatg atgaattgca
    12301 ggaaatcgct aaagaattag tccgtaacga attgttggaa aaaacaaata tcggtctgga
    12361 tttctttgat gcaacgatca accgtatcgc tgcttgggtc atcggtacga gaaatacaca
    12421 aaaagcactg ctgaaagcta tgctggaacc agttgagcga ttgaaagaaa tggagctggc
    12481 ttttgacttt acttcaagaa tggcttatac ggaagaattg aaagatttcc cgtatgccga
    12541 tgtatggaat tatttctgtt acaaaaatca agttccagtt ggtttggatt ggctggaaga
    12601 agtccaggaa tatcaaaaag acgtgttgga attaagaaaa taggagtgtg gctatattga
    12661 aaaaaataga tattttacaa gcgccttatg tgaaagaaat gatcgaaacg acgtcgaatc
    12721 tttatcgctt gggatgggat gaaagaaatg gcgggaatat ttcttattta ctaaaagaag
    12781 aagagatcac accgttcttg gatcctgaaa aagtgatccg ccgcatctcg atgatttttg
    12841 atgccagccg tttagcagga tgctatttta ttgtaactgg ttcaggaaga tattttaaaa
    12901 atgtagcgag cgaacctgcc gagaatcttg gaatcgttcg agttgctgaa gatggcaaaa
    12961 cactggaact tttgtggggg ctggaaaacg aatgccttcc tacaagcgag ttgccaagtc
    13021 atttcatgag tcatatcgcc cgtttagaag tagacccaga taatcggatc gttatgcatt
    13081 gccatgctag tcatctatta gcgatgagtt ttacgcatga attagacgaa cgttccttta
    13141 gtcgtacgct atggcaaatg tgtacggaat gcttagttgt ttttccagaa ggaatttcca
    13201 tcattccgtg gatggttccg ggaacaaatg agattgggga agcaacagct gaaaaaatga
    13261 aagaaactcg attggtttta tggccacaac atggaatcta cgggtcagga aaagacatgg
    13321 atgaagtctt tggtttgatc gagacagcag aaaaggcagc agaagtctat acgtacgtca
    13381 aagcgcaagg accaatcttg caaacaatca cggacgaaaa cctgtggcat ttagcagatg
    13441 cgtttggtgt cactccaaaa gcaggttatt tggaggaagt tcatacgaaa gcaggtgtct
    13501 gacatggtga aaaaagcttt ttgcatgaaa gtttacccag aaaaacaaga agaatacaaa
    13561 aaaagacatg atgaactttg gccagaaatg cgtacagcac ttcgtgaaca cggggtcatc
    13621 gactattcga tctatcttga tccgagtaca agtttgttat ttggttactt agtgatcgaa
    13681 gatgaaaagt tatgggaaaa aatggcaaat acatctatca atcaaaaatg gtggaagtac
    13741 atggaagata tcatggagac aaatccagat gcctctccag tcagttggga attgatgcca
    13801 gtctttgaac tgtagcaaca agcaactggg caaccggttg cttggggttc tttcgttttt
    13861 attgtgaaaa ataatacaaa ttaggaggaa tagaaaatga gtaatcgaat gattttaaat
    13921 gaaacatcgt attttggaaa aggagcgatt gagtcgatcg tccctgaatt tcagcagcga
    13981 ggattcggca aagcagctgt cattactgac aaaggattga tcgagcacgg tatagcaaca
    14041 aaagtaacag aacttctaga taaagcagca atcgcttatg ctttatacga cgggatcgta
    14101 cctaatccaa cgatccaaaa tgtaaaagat ggagtggctt ttgttaaaga ggcagaggca
    14161 gactgtttga tcgcaatcgg tggaggttcg ccaatcgata cggcaaaagc cattgggatt
    14221 attttgacga atccagagtt ttcagacgtc attagtttag aaggtgttgc tgatacgaaa
    14281 aatccatgtt tacctatatt agctatacca acgacttctg gaacagcagc agaagtaacg
    14341 atcaactacg tcatcacaga tgaagtaaat caccgaaaat ttgtttgtgt tgatcctcat
    14401 gatatcccaa tcgtcgcgtt catcgacagc gatatgatga tgggaatgcc gaaaaaattg
    14461 gctgcatcaa caggtatgga tgctatgacg catgctattg aagggtttat cacaaaaggc
    14521 gcttgggaaa tgactgatat gctgcattta aaagcaatcg aaatcatcgg ccattctttg
    14581 gaagcttctg tagatggcga tcaaaatggg cgagaaaaaa tggcattagg acagtatatt
    14641 gcgggaatgg gcttctcaaa tgtcggttta ggactggtac acgggatggc tcacccgtta
    14701 agtgcatggt acaacattcc tcatggcgta gcgtgtgcag cacttttgcc aactgtcatg
    14761 aaatataaca aagaatatac tggagaaaag taccgtgaga tcgctcttgt tctagggatt
    14821 aaaggagcag ctgaaatgtc tttagaagat gtaagagaag cggcttgtgg tgagatcgat
    14881 cggttgagca aagcggttgg aatcccagaa accatttctg aattaggtgt aaaagaagca
    14941 gatattccag caattgcaga agatgctttg cgagatgtat gcacaccagg aaatccaaga
    15001 gaaacgacag tagaagaaat cattgcttta tatcaaagtt tgatgtaaaa acgaagcgga
    15061 tcttcaacat taaattgcct gtaaagagaa atggtagttt atatctggat atctctttta
    15121 aattgatggt atttccgcta taatttttct tataaagaaa taggagaata ttatatggaa
    15181 aataaaaagc cttatggaac tgtattgatc aaagcctcta aaatactaga ctatttagcg
    15241 gaaaaccaag atgtctcttt gcagacgatc gcaaagggtg tgggaatgac ctcttctaca
    15301 gtcttgaaaa tactagatac tttgttgatg atcggctacg taaataaaaa ttcagagaaa
    15361 aactatcgtt taggtgcaaa gcttattcgc tacgcgaata aaaacattga acaaatcgat
    15421 ttggtagagt tgactttacc gtttttagaa cagctgcagc aaaagatcga tgagactatc
    15481 cacttagggg tattggacaa caatgagatc ttgtacgtga acaaactaga tccaaaacat
    15541 caaacgatcc gcatgtcttc aaaaatcgga atcacccgac cattatacaa ttctgcgatg
    15601 ggcaaagccg tattagcaga attcagtgaa gagcagtaca ctgattatct tgaaaagcat
    15661 ccgttgatcc cttacacaga atatacgatc accaatgcat tacggttgaa aaaggaaatc
    15721 aaaacggtaa aagaaaccca catcgcattt gacgatgaag aaatcgaacg tgatattttt
    15781 tgtataggag cctcaatcgt gaaaaacgaa caaatcattg gtgcatttag tgtaagtatg
    15841 ccgaaatatc gtttaacaga tgagacaaaa gaacaaataa tcagtgccct caagcaaaca
    15901 aaaagcgaaa tcgagcaaag aattcaaaaa taatgaaaaa agcgtttgca atttttcttt
    15961 tctgccgtat aatatgggta tagatttcca agttataaaa taaaatttct aaataggaaa
    16021 taggtggaga agatgaaaaa aattgatatt ttatctcgat tgaaaaacgc cggagtgatt
    16081 gcggtggtac gcggaaaaag caaagaagaa gctttgaatg cttgccacgc aatcatcaaa
    16141 ggtggtctaa ctggtattga gttgactttt acagtccctc aagcagatca agtaatcaaa
    16201 gaacttttgt cattctacaa agaccaacca gaaatagtga ttggcgcagg cacagtatta
    16261 gacgctgtca cagctcgctt ggctatctta gctggcgcag agtatattgt tagcccttcc
    16321 tttgatcaag aaacggcaga gatgtgcaat ctgtatcaaa ttccttactt accaggatgt
    16381 atgactatta ccgagatcaa aacagcgctg aaaagcgggg tagatatcgt caaactattt
    16441 cctggaagcg cttatggacc aagtatcatt tctgccttca aggcgccgat gcctcaagtc
    16501 aatatcatgc caactggcgg tgtgagtctg gacaatatga aagagtggtt cgatgctggt
    16561 gtcgtaacag tcggagtagg tgggaacctt ttagcacccg cagctacagg agattttgac
    16621 aaagtaacgg aagtcgcgca acagtatgca gcaaaaatga aagaaatcaa gaggtagctg
    16681 cttatgggaa aagtagtgac actcggagaa atcatgttgc gattgtccac agagcaggga
    16741 acccgtatcg attcaagtga acgattcgct gcccattatg gcggagggga agcaaacgta
    16801 gcaatttctt tagctaatta cggacatgaa gcgatttttg ctacaaaagt acctgataac
    16861 gcattgggaa aagcagtcaa aaagcacttg caatgttatg gagtagatac gaaacaggta
    16921 ttatctggtg gatcaagact aggtacttat tatatggaaa ctggtagtgg cgaacgcgcc
    16981 gcctcagtga tctatgatcg tgccggatca agttttgctg aaatggatca tttggaatgg
    17041 tcgctagagg agttattcca aggaatagat atatttcatg tttcaggaat caccccagct
    17101 ttgtctaaaa aatggcaaaa aatgacgaaa caggtgatag aagctgcaaa aaaagctggc
    17161 tgcctgatca gcttcgatat caactatcgt ggaaaattat ggacacagca agaagccagc
    17221 gaagtaatcc atcagctttt acctttagta gatatctgct cagctggaaa aatggatgct
    17281 ctttatttgt taggtatcga gaaagcgcca gaagcagaag aacaacctct aatttattat
    17341 tatcaaaaaa tgcaggaaaa gttcccgaat attcaggtgt tttattcgac caagcgtacc
    17401 gttcattcag caagtgaaaa tgaattgaag gggacattgt ggatgaacca tgaatatgtg
    17461 gaatcccaag tccatagaat caccccaatc gtggatcgag taggtggcgg agatgctttt
    17521 gcaggtggcg tgctccatgg gattttatcc aatatgtctc cgcaagaaat cattgatttt
    17581 gctacggcag cttctgcctt gaagcatacg atccatgggg actgcaacca atttagtcaa
    17641 gaagaagtcg cacaattttt agcatgcggc tctggaaaaa tcattcgata gaaggagtag
    17701 aagaaaatgc aagaaatgga aacacgttat acacacagtc cagaagatat ccgtcattat
    17761 tcaacggaac aattgagaaa agaattttta gtagaaaagg tatttgaacc agggaaaatc
    17821 agtttgactt atacgcacaa cgatcgaatg atctttggtg gagtgacacc tactgaaaaa
    17881 gaattagaaa tcacattaga caaagaacta ggtgttgatt acttcttaga gcgtcgtgaa
    17941 ctaggtgtga tcaatatcgg tggaccagga ttcatcgaga tcgatgggca aaaagaagaa
    18001 atgaaaaaac aagacggata ctatatcgga aaagaaacac gacatgttgt attttcttct
    18061 caagatgctg aaaacccagc taaattctat attagttctg ttccagctca tcataaatat
    18121 ccaaatgtaa aaatcagtat cgaccaagta aaaccaatgg agactggtga aggcctgaca
    18181 ctgaatgaac gtaaaatcta ccaatacatc catccaaatg tatgcgaaag ctgtcaatta
    18241 caaatgggtt atacgatttt agaaccagga agcgcttgga atacgatgcc ttgtcataca
    18301 catgaacgtc gtatggaagc ttatgtctac tttgattatg ccaatgaaga tacacgtgtg
    18361 ttccacatga tgggcaaacc agatgaaaca aaacatttag ttgtagacaa tgaacaagcc
    18421 attatttcgc caagctggtc gatccattca ggtgtaggta caagcaatta ctcattcatc
    18481 tgggcaatgt gcggagaaaa tatcacctat acagacatgg atatggtgca aatggatcaa
    18541 ttaaaataag cataagggag agaaaatgat ggaatttagt atggatatgt ttcgtttaga
    18601 tggaaaagta gcattagtca ccggtgctgt ctatggtatt ggatttgaga ttgcacgctc
    18661 tttagctaca gcaggagcaa aaatcgtatt taataacttg aatcaagaat cagttgatga
    18721 aggtatagcg cattataaag aagcaggcat cgatgcaaaa ggttatgtct gcgatgtgac
    18781 cgatgaagaa gcggttcaag cgatggttca acagatcaaa gaagatgtag gttcagttga
    18841 tattctagtc aacaatgcag ggatcatcaa acggacaccg atgatcgaaa tggatgcggc
    18901 agacttccgc caagtaatcg acgtggattt aaatgcccca ttcatcgttt caaaagcagt
    18961 tattccggat atgatcgaaa aaggcggcgg taaaatcatc aatatctgct ccatgatgag
    19021 tgaattagga cgcgaaacgg tcagtgctta tgctgcggca aaaggcggat taaaaatgct
    19081 gacgaaaaac atcgcttctg aatacggtca atacaatatc caatgtaatg gaattggacc
    19141 aggttatatt gctacaccgc aaactgctcc attacgcgaa acacaagaaa acggtgaacg
    19201 tcatccattc gatcaattta tcgttggacg tacgccagca gcacgctggg gcgagccaat
    19261 cgatttggct ggaccatctg tcttcttggc ttctagcgca tctgatttcg ttaacggcca
    19321 tgtcttgtat gtggacggag gcatacttgc ctatatcgga aaacaacctt aaaagagctt
    19381 tagtacactg tttagtggag aggttgtgaa atcagcggat tgaacgaata ccgaaggaca
    19441 gctgattaaa catcatttat tcgaaaaaag aggctgggac agaagcattt aactccaaga
    19501 aataagaagg aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg
    19561 aaggagttgc ttttacttcc gccgtttgta cgtgtttaga gcgtgagaca aaagtgttct
    19621 ttacttttgt cccacgctct tttctgtgcg tcttccatac ttcactaagt cgatccctct
    19681 tgcttcgcac caatccttca ctggtccgga aaagatcaga gattgttggt gtagggccgc
    19741 ggtattcgtt gcgccgacca tagtataaag cagacgaagc tcttcttgcc attgcttcat
    19801 cagtataata gtttcttcta cgccgtgatt catcagatgc gtcagtacgg ttcctgaagt
    19861 acccacggca tttgcgccga gacaaagggc tttaaatatg tcataggcat tgcggatacc
    19921 tccggaggct aggatttcca tagaagtgtc tgcttcattt gcttcaagca atgaagagac
    19981 tgtcgattgc ccccagtcag ctaaataact cagttcccgc ttggagcgac gggcgttttc
    20041 gatctgggtg aagcttgttc cgcttcgacc gctgatatca actgtatgaa ctcctaaagc
    20101 agctagatca ttgagcgttt ctcttgtcat gccaaaaccg acttctttta cgatgagggg
    20161 gacgtcaatg gctgtttgag tttcttgaat aagtactttc caattggtaa aatcacggtc
    20221 tccctcaggc ataaccaact cttgaggtgc attcaaatga atctgtaagg catctgcgtg
    20281 aaacaatcgg atagcttctt tggctctttc gacagaagtc cctgcaccga tgttggcaat
    20341 gattttcccg tgaggatatt cttgtcgcat aatcgtataa gtatcggcta aagaagggac
    20401 tttcaaggca gcgctgactg aaccagtggc aatcatcaaa tctgcttctc ttgcgacgat
    20461 tgcaagatct tggttgattt tttttgtttt ttcgcttccg ccagtcatcg cattgatata
    20521 aaatgggctg cttagtgtaa acccaactgc ctgtgtactt agatcgacat cagaaactgc
    20581 tatttgcggc aaagggttat ggatgatccg tacgaagtca aattcgtttt tttgtttatc
    20641 atgaaaggct ttagctagtg aaacatgttc gtcttttcga ttcatcggtt ttcctttctt
    20701 tgatcgctat agacatgtaa cggcagtgga gtgatttctg ctttttccca tgcactcatt
    20761 aaaggaagaa tgccagattt ctggtcaaca attacgattc cgcaatcgcc cccacctgca
    20821 ccagaagatt ttgcggctcc ttcatactgt tcagctaaat tacacaattt gttcaaagca
    20881 ggcgtttcga tgacgacccc agtgattgca gataaatcat gcagtaattg tcggtttttt
    20941 cgaatcatct gttggatcaa cgttacatta ttttctttaa accctttgat catttcgttg
    21001 acacattctg tactattttt taagaaaagc tgataagcca ccattttatc ttctctcgaa
    21061 cggtgaactt gatcgaccaa atcagaagta gaggcagggc tacccgtcca accaatcaat
    21121 aaacgtaaat cttcaggagc aatcaatggc tcaatggata gacctggcca atccagggca
    21181 agtaactcac tgatagaatg ctgagtttct tgttcttgga gccaaggatg gtcgaaggtt
    21241 gagaaagcga tccagccacc ataacagcta gcagcgatgt cgccgcagga accattatct
    21301 tgaactgcta aattggctag tgctgcaatc ttgaaaatct ccaactgaga taaattcaac
    21361 gcgtaaaaaa cattcaaggc tttgaccgtt gcaacggtca cggcaccgct agaacccaat
    21421 ccatatttcc ggccatttga actgtctaac tcacttgtta ctttcagatc ataaaaggat
    21481 aaaagaatgt ttttttcttg tgcatacttt tcagtcaagc gaatagcagc aaggatataa
    21541 tgaaaaggat tttcccgaat atctaaaact aattctccgt tgcgtcttgt ccaacgtaca
    21601 ggcatcccac tatattgtgc agattggata cttccgactt ttcgtgcaga ttctacagtg
    21661 actgtcacga attgatcgac tgcagcgata actgctggat ggcctgtttc aacaactgca
    21721 tattctccgg caatatagag tttgcctggt gcagatactt caatcataaa aatctccctt
    21781 tattcaataa tcgcaattcc tggaccagca tgtgcagtaa ttacttgttc tttgctaaat
    21841 aatttggtaa atgtttcttg tacctcagat aaatggctgt tttccactaa aactttgaca
    21901 ttagggccag catccatcgt aaagtagcat ggaatgcctt gctttctcaa ttgtcgcacc
    21961 gcatccatcg cttttaagct gtcaggagac cagtaagtga atggaggctg ggcagctaaa
    22021 gtcgttccat gcatttttag tccgtttctt tccatcgttt ctccgagaag ttggaaatct
    22081 tttgttttga ttgcttgttt caattgatat agatcccctt caacggaatc taaccagcct
    22141 tgataaaaac tggatgtttc gactgtccga cgcatcccat ttctgctgga cacttctttt
    22201 ttctggtcgt tgatcaaaac gaaaaccatt gctaaatcgt cttcgaaaga atcggaaggg
    22261 actggcttag cgtaagaact taagtcgtca tggccttttt cccattcgac gaaaccaccg
    22321 aaaatacttc ggcaagctga accagacccg cgtcgagcaa atcttgaaag agagagatca
    22381 tctaatccaa gcttaagagc agtattgcaa gcgcctgcta aagcagctag cccgctggca
    22441 gaggaggcta atccagctgc ggtaggaacg aaattctgac tgattactga agcttttagt
    22501 gagaggccgg cttctttacg aaaaaggtca agaaactgac tgactttttt tgttgctttt
    22561 tcgtcttgca aggtgccatc tagataaaat tcatctacca tatagctatc agaaaagatg
    22621 acttctgtct ctgtataaaa tgcatccaat gttaacgaaa ggctgttgtt cattggaagg
    22681 atgagttctt catttttctt accccaatat ttgattagag caatgttggt atatgcgcgt
    22741 gctttgcctt taaacatagg tatgtactcc taatccttgt atccaagttt cagcagcacc
    22801 cgcatcttca agtgcttgac tgatttcttg ggcttttgtt tttgtttgtg ctaatgcaat
    22861 catacagcca ccgcgtccac cgccagttaa tttggcaccc aatgccccgg tatcttttgc
    22921 tgtttggatc aatagattaa gaaaatcatt gctgattgtc agcttttcca gaagtgattg
    22981 tgattcatcc attgtctgtg ccaacgtttc tggtgaattt tcaatgattg cttgttttgc
    23041 ttgcttcgtc aagtatccta atttttggat catttgtcca gtttcatgag gctgggtttc
    23101 aaagaggtga gcgacatctt tgacggcttc tcttgtttgt cctttgattc ctgtatcagc
    23161 gacaatcaaa aaagcatcga tgttcaaaga aaagtagtcg aaaggatgcc cttttgtaaa
    23221 ataaatcggc tgcaagctgc tagtagcggc tgcatcgatt ccactaggat taccatgggc
    23281 gattttttcc gaaagctgga cattttctaa tagtatttca cgagacaaag gaaatgctaa
    23341 gtaatcataa aaagcacgag tgactgctgt ggcgactgca gcgcttgatc ccattccacg
    23401 ttcagcagga atcgtgcttt caatggtcag ttgcaagttt ttttggatgt catgctgttt
    23461 ttttaagtga atgaataatt ttttgatatt ttttaatgca tgaggagctt cggctaaatt
    23521 tcctgaatag taggaagaaa ccagttgatc gtccattgca tccagctctt caaggaatgc
    23581 ggtgactttt gttgcataga aaggaaaggc aatcgctggt tctccataaa caaccgcgtg
    23641 ctcgcccatc aatatgatct ttccgcttga ttctccttgg ccatagtttg ccataatcta
    23701 actccttctc acgtaaaagt gatttttaag caaaaaataa agcgcccaaa acgagttgcg
    23761 ctgcttcacg aatttttttg tccactaagg gtctcaaaaa acattcctcc tttattttac
    23821 taaaaccatc tcagaagtaa aactaagaat acgttttcta aagaaaaaac acttttttct
    23881 taagaatttt ttgacttttt ttcttctttg actagaaaaa aatacaattg acactactag
    23941 atattggggg tatatttaaa aaggttggag ttaaacacaa tatttagtga tgaagtgagc
    24001 tggaggtaaa tgagcgtgat cgttttagca ggtacaattg gtgccggaaa atcaagttta
    24061 acagaaatga tggctgaaca ctttgatagt caggcatttt atgaatcgat tgatgataat
    24121 gaagtcttgc ccttatttta tgcaaaccct gaacagtatg cttttttgct gcaaatttat
    24181 tttttgaata aacgttttgc aagcatcaaa caagcaatga aagatgacaa taatgtattg
    24241 gaccgttcga tttatgaaga ttcactgctt ttccatctaa atgcagatct aggaagagca
    24301 acagaaacag aagttcgtgt gtatgatgaa ctgctggaaa acatgatgga agaacttccc
    24361 tatgctgccc ataaaaaaca tccggattta ttagttcata ttcgtgtatc ttttgatacg
    24421 atgttggagc gtatcgaaaa acgtggtcgt tcgtatgaac aattgtcctt tgatccaagt
    24481 ctatacgatt attacaaaga attgaacaga cgttacgatc aatggtatga agaatacaaa
    24541 gaaagtccaa aaatccaaat cgatggagac cgctataatt ttgtggaaga tcctcaagca
    24601 aaagaagaag tcttgaaaat gatcgaagaa aaattagcag agattcgcca aaccaaagta
    24661 gccatttgat ttacagttgc tcaaataaag ggtaaacctt tatttgagcg acttttttct
    24721 ttatactgga aacaaatgtc aggaggatag agtatgcggg aaaaacacta ttttaatcaa
    24781 gaccgtaatt tttggatcaa tgtacagcaa aacgatgtgc tagctgttaa aaacttaaaa
    24841 gaagaatatg gcattagtga cgagatgctg acttattctc tagataaaaa tgaacgggcg
    24901 cgcgtagagt acgattcttt tgatgaagcg ttactgcttg tatcaaatgt tccgcaccag
    24961 caaaaagtcg ataatcatta tgaaactagt cctatcgctt ttattttaaa agaagacggt
    25021 ttgtttacat ttaccacgcc gaataccgag tacgtgattc gactaattcg atcgcttttg
    25081 gaacgaatgc cagacatgag tgtatacagt ttattgtttc gtacattgtt tttgatttct
    25141 gattcctttt ttcctttaat cgaggaagtg aatagtgaac gtcagcggct taatctgaaa
    25201 ttaagagaaa aaacaacgaa caagaatctg ctgcaacttt cagatttaga gatcggtttg
    25261 gtttacttag ttacaggaac aaaacaaaat gtagtacttt tagaacaaat caaggcattg
    25321 gctatttatc gcaagttgtc agaaaaggaa aaagaagagt tggacgatgc gctgatcgaa
    25381 gcacgacaag cagttgaaat gacgaactta gcttcgcaga ttttagacca gctctctggc
    25441 acttataata atttgctgaa taacaacttg aatgacacga tgaaattttt gacggtctgg
    25501 tcgctgatct tgaccgttcc aactattgtg acaggattct tcggaatgaa tctccagtta
    25561 ccctttaccc attccgtttt cggatgggga atcgccttga tcatcagttt ggtcttatct
    25621 atttggatgc ttattgcact gtggcggcgg attcgttgat ctagtctttg atctgcaaac
    25681 caagggcttg ggcgatcaca agtgcttgct cttggttgac gattagtccc gccaaagaat
    25741 cttgagataa agcgattgct gtgaagaaat tagtcgtaaa gtctaatccc ttcagagaag
    25801 ttcgaaacca gttcgaaccg gtcaactgat tgtcagacaa aaaaaggttt ttccaagtga
    25861 cctcataaaa ttcgctgtct tctaattgac aatgatcgaa ggagacagct ttcaagtttg
    25921 tactactaaa ggaagccatc gaagcaatac aatcagtgaa agtacagtct cgaagataac
    25981 tttcggcaaa attcgtacct gttaatttac attgatgaaa cacgacttgg tggaaactgc
    26041 caccaatcca ctccagattg gaaaaatcac atttttcaaa aatgacatta ctgcattcaa
    26101 aatgacgtaa aactgttttt tgcatcgtaa gtttttggat atgactctct cttaatacca
    26161 tatttttggc atcgagatag ctttggtcac ccccgttgat cagaagacca gagaagatct
    26221 cctcatcttc taaataaaac tctccctttg taagaagagg aagagaaggt ggaataggtt
    26281 cgattttttt catgtgggtt cacctcgttt ttctttagta tagcaaagaa gcgggaatca
    26341 ctgctagaaa gtctgctaat ctaatcattt tcagaaaagg aagacaaact gtatgaaaaa
    26401 cattgacaaa aagattagtt tttgctatac tatgatggtt gagaaataaa agcagaagca
    26461 cccgcttctc gccttagttg ataatgtcac tgggctagat agttttcact ggttctatta
    26521 ggtgaagtac gcgcgggttc tgtaagagaa ctcgtttttt tattgccgtt tattcggtaa
    26581 gcttttcttt ctctcataat atttggaggt gaatgaccat agcaaaggat atgatggtta
    26641 acgacggcat tcgtgcacga gagttacgat tgatcggttc agatggtgag caattaggag
    26701 ttaagacaaa agcagaagca ttgaatattg cagaacaagc aaacttggat cttgtgttag
    26761 ttgcccctgg tgcgaaacca ccagttgcgc gaatcatgga ctacggtaaa taccgtttcg
    26821 aacaacaaaa gaaagaccgc gaagcgcgta aaaaacaaaa agtgatcaat gtaaaagaag
    26881 ttcgcttaag tcctacgatc gacttgaatg acttcaatac aaaacttcgt aatgcacgta
    26941 agttcttgga aaagggcgat aaagtgaaag cttctatccg tttcaaaggc cgtgccatta
    27001 cccataaaga aattggtcaa aaagtcttga atcgcttagc tgaagaaact gcggatattg
    27061 caacagtgga acaaaaagcg aaaatggacg gacgcagcat gttcttgacg ctggcaccga
    27121 aaaacgacag taagtaattt gaatgactaa ctggctgttg gacagccgat agtcggataa
    27181 cgaaagattt tgaggaggaa atatagtcat gccaaaacaa aaaacacacc gcggatcagc
    27241 aaaacgtttc aaacgtactg gtaaaggcgg attgaaacgc ttccgcgcgt ttacaagtca
    27301 ccgtttccac ggcaaaacaa aaaaacaacg ccgtcaattg cgtaaagcaa gcatggtttc
    27361 tagtggcgac ttcaaacgta ttcgccaaca actagcaaaa atgaaataag aagtacaaat
    27421 aacagaatct gaagatttat ttttattagg aggaattata catggcacgt gttaaaggtg
    27481 gaacagtaac tcgtaaacgt cgtaaaagag tgctaaaatt agcaaaaggt tactacggtt
    27541 caaaacacac tttatttaaa acagcaaaag aacaagtaat gaattcatac aactacgcat
    27601 atcgcgatcg tcgtcaaaag aaacgcgact tccgtaaatt gtggattgct cgtatcaacg
    27661 cagcagctcg tatgaatggc ttgagctact caaaattaat gcacggtttg aaagttgctg
    27721 aaatcgacat caaccgtaaa atgttagctg acttggctgt taacgatgca gcagcattta
    27781 ctgcattggc tgaccaagca aaagaagctt tggctaaata agctaaacaa ttataaagag
    27841 gaaagaagat aacgaaaagt tatgttcttt cctctttttt tatttacaat cctccatcaa
    27901 atgaaacagg acaataacgt ataagtctaa aatagcataa ttaaggtttt ttaattgaaa
    27961 actgaacatt tatggtcacc ctttaatgaa agcgctaact acataagtta gaatgagttt
    28021 gactgatata ttagtttgct tatcagaaaa acaaaatgga cggaggaata acatgagtga
    28081 tattattatt ggtattttgt tagttatctc attctttttc atggtctggt actgtgtaaa
    28141 aggctacaac ttgatggtcg gctttgccat catggctact gtatggatgg gattagcgct
    28201 agtcggaaac acgttttcac caaacccggc gatggaaggg caaggagtaa ttgatgtgtt
    28261 gacgcatatc tatacgacgg ggccagctga gtacgccaaa tcgatcttgg taaatgtctt
    28321 ctttggtgcc tttttcgggc gtgttctagt agatagcgga atcgcagcta ccctgattcg
    28381 aaaggtagtt gaacttggag gggacaagcc aagaatcacg atgagcttac tatgtattgt
    28441 aaccgctgtt atattcatgt cgatgacagg aatcggacca gtgatttcta ttgcagttat
    28501 tgtgttgcca atcttgatgt cattaggtat ttcagtaccg gttgcactgt tctcatttat
    28561 gggctcgatt atggctggaa tctttgctaa tatcgtcaat ttcaaacaat atcaaacgat
    28621 ttatgctggt ttcaatccag cggctgaaag ctatacttat aatgactatt tccaaattgg
    28681 tatgattggg atgattgtaa gcttagttgt ggtactaacg gtcgctaata tatcaatgaa
    28741 caaaaagaaa cgctatgcaa tggcagcaaa cgtaccagct gaaggtggcg acgcaccaat
    28801 gatctcatgg ttagccgtat tattaccagt tttaggggtc gttcttttag atcttccaat
    28861 catcttaggt tttattctag caggtatctg ggcattgctg tttactggaa aattgcgcgg
    28921 aggttataaa gaaatctgtc gtcagtttgc gaaattattt acagatggcg cagtagatgt
    28981 tgcgccaatg gttggtttct tgatgacctt agcgatgttc aataattcag ctgcgtatgc
    29041 ttctccttat ttttcagcta tttttggaga ttggataccg caatcaccat tagtcttggc
    29101 aatcgtattt gctatattga caccactagg atttttccgc ggtccaatga atctagtcgg
    29161 ttcaggctca gctattttag ctgtcgtatt agctgttaat ccaacgatgt cgccagcctt
    29221 tttgttcccg ttatttgcaa tcacaacgat tgctcctcag catttagata ttacacaatc
    29281 ttgggttgct tggggattag gttatacaaa agtaacttct cgagaatata tgaagaaatc
    29341 catcccaact ggttggatca tcggagcgat cttatgcctg atcacgttct tattgtacgg
    29401 gaacgcctag taaacaaaac gtcgataaaa acgattagat gaatggagga aaagaaaatg
    29461 aaacgttttg tgcgaatggg aattgatgtt ggcggtacac atacgaaagc agtcgcaatc
    29521 gataatgcga cgcacgaaat catcggaaaa tcttcagtga aaacaaccca cgatgatgtc
    29581 cgtggagtag ccgcaggtgt cgttcagtct tttcaaaatt gtttgctgga aaataatatc
    29641 agtccagaag atgttgtgtt tgttgcacat tctaccacac aagcgactaa tgcactgatt
    29701 gaaggagacg tagcaaaagt cggcgtaatc gggatggcaa aaggtggatt agaaggtttt
    29761 ttagcaaaac gacaaactag attgaacgat atcgatttag ggaataagaa aaaaatagag
    29821 attgtcaatg cattcttacc tgtcaaacac ttaaatgtag accgtgtttc agaaacgatt
    29881 tcttctttag aaagagaaag agcggaggtc ttggtttctt ctatggcatt tggagtagat
    29941 aatggggaac cagaacgagt tgtttatgaa gcagcatcgg taaaatcgat ccctacaacg
    30001 atggcttctg acatcacaaa attatatgga ttgacaagaa gaactcggac agcagcaatc
    30061 aatgcatcta ttttaccaaa aatgctagat acggcaacct ctacagaaga ttccgtacga
    30121 gaagcagggg tcaatgtttc tttgatgatt atgcgcggag acggcggagt aatggaaatc
    30181 aatgaaatga aaaaacgacc tgttttaacc atgctttccg gtccagcagc atcagtcatg
    30241 ggctctttga tgtacttgag agcgtctaat ggtgtttatt ttgaagtagg cggaacaaca
    30301 accaatatcg gggtcattaa aaatggacgt ccagcaatcg attattcaat tgtaggtggc
    30361 cacccaacat atatctcttc attagatgtt cgggttctag gtgtggcagg cggttcgatg
    30421 gtacgggcta atcagtcagg aatcatcgat gtcggtccac gttctgcaca tattgccggt
    30481 ctagattatg cagtatttac ggagacagaa aaaatcaaag gtcctaaggt tgaatttttc
    30541 tctcctaaag aaggagaccc tgctgattac gtcaaggtag tgatggaaga cggagaagaa
    30601 gtgactatta caaatacatg tgcagccaat gtccttggat tagtgcaaga agaacatttt
    30661 tcttatggaa atgtcccatc tgcacgaaaa gccatccaag cattagctga ttattgtcat
    30721 acgacggttg aagacatcgc agaacagatc atggaaaaat cctatgctaa gattgaaccg
    30781 gtgattttag aattggcaga caagtatcac ttggagaaag atcagatttc tcttgtaggt
    30841 gtagggggcg gcgctgcctc attgattact tactttagta ataaaatggg tgtgaaatat
    30901 tcgattcctg aaaacgccga agtgatttct tctattggtg tagcacttgc aatggtccga
    30961 gatgttgtag aacgtatcat cccttcgcca agtaaagaag atatacgatc gttgaaaaat
    31021 gaagcgatga ataaagcgat tgaatcaggc gctacaccag aatcgatcga agtccacgta
    31081 gaaatcgatc cacagacttc aaaagtaacg gctatcgcta ctggttctac ggaagtgaaa
    31141 gcaaccgatc taaccaagga gatcacaaca gaagaagcac tagagcttgc tgcagaggat
    31201 atgcgattaa ataaaaatga agtttgctta ttggaaaata cacctttctt ttatgtatgc
    31261 ggcgaacaga atcgttcaaa aaatgctgga agtcttcgga tcatcgatca aaaaggattt
    31321 atcaaggtcc aacgtggaca tgcttcatgt atgaaaacaa ctgcagccaa ttatatgaca
    31381 gctgtcgaac aactttggga agatatggca gtttatcaaa ctgaattgat tgcccgacca
    31441 gaattttatc tctgcttagg agcaagagtc tctgatttta cagcgacgga tctggaacaa
    31501 ctacagcttt tgatggatct ggaagtatct actatggaac cggaggaaga agtgatcgtc
    31561 gttgccggaa atatcaaaca aacataagtt agaagagtta ctaaacgaat tacaacagat
    31621 ccccgaagaa atttggggat tctaccagtt tcggcgagat ttattttgga aaaagattcc
    31681 tttgtccaag cagaaaattc ttatacaaca atcaatcgat tgtggtatcg aaacggcatg
    31741 tagcatcaaa aaaaagtacc cttttgccga tgtaggagaa atttgtgaac aaatggctgt
    31801 tccaatcgtt tcctgtgaat cagagcaaat aaacgaacga atcacttttg caacttatgc
    31861 agaagatgaa gggattcgat tgatgacgga gccgttagaa aaattaaaat gttcaggact
    31921 agcttcgatc tctaaagaaa cagcgcaagc tttgattatt ggacatgaac tatttcacca
    31981 catcgaagct tctgttaagg gaatttatac gcaaagcgaa aaaattgtgc tgtggcggtt
    32041 gcctttttat acacatcaat caaacattcg tgcattgagc gagatagcag cgatgagttt
    32101 ttcaaaagag atgaatcaaa gcgatttttc gccttatgta ttagaggcag tcttactttg
    32161 gccatataat gaaattcgta gccaagggat cttagaagaa ataaaaaaaa tagaaaaaag
    32221 atgtacggag tatgatttag attacaaata aagagactgt gacaaaagtc gtgtcacagt
    32281 cctttttttc cgaataaacg atgttctcct gtcaactcct cggtcacaag tcaaaatatt
    32341 caacaaacat gagaagctgt tttttgaaat tgttccttgt gactcggaga tgaacggcag
    32401 gctcacgacc tcttggaaaa cggtgttcaa aagcttgcat ctgcggtaat aagtccagcc
    32461 aagttaaaaa cataagaagc tatttttact tggctgttct tattacttga tgcagggcag
    32521 ctttttcaca acctctcaat aaacggtgtg caatcagctg accctcggta ttagctcaaa
    32581 aaaaacggca aaatatgagg aactattttg ccgtttcttt ctctaatact caggtcaaaa
    32641 cgctgattcc aaaacctctt atttgatggg tctgtcctga atatcttcaa aataatcggg
    32701 gtaattatga atcacgtatt cttgctcctc gataatcata tgtaaatgca tcgtgcaaag
    32761 aaatccgact tcatcaaagt tatgatcaat cattgattga agcattgtct gatgttcatc
    32821 taatactcga ccccagtcta attctgaaat cgtcaaacgt aaccatctga aacggttcaa
    32881 gtgcgtacta taactttcta gccaatccca aatttctcgt tttccagcaa tttcataaca
    32941 agttcggtga aaatcagtat ccaaatcaaa aaaagctttt ttattttgag cgattactgc
    33001 ctgatcggtt tgttctagta ttttttctag tttagcttga tcttgcttgg tcattttcgc
    33061 actgcattct tgcaggatcg gtttttccaa cttttcccgc gtataacggg ctaatgaagc
    33121 agatcggata tcgatttttg aaacataagt gccggactgt ggaatggttt ttacaagctc
    33181 ttgattgcgc agttggatca gtgcttctcg aatcggtgta cgcccgatag ctagttgttc
    33241 ttctaacact ttatcggaga ttttacttcc aggtgctaac tcggaataaa tgatttgttt
    33301 acgtatagat tcataaagct tgctgttgca aattattgat aaccatttaa ccttcctttc
    33361 tatgcagata taatctatta taacataaat cgcttacaaa tcgtgtgggc ataaaaacac
    33421 agtctgcaaa aaaagccctg ataggcatgc ctattagagc ctcgaaaaga aaaatattga
    33481 atcaatctgg tcgtacctct tggatcggtt tgacacgacc gccgattctt ttagcaaaag
    33541 cttcggattc ttttttgtct ttgaaaatga gcagattgtc taagtttttt tcccgagtgc
    33601 gacagccagt tttatcgatg taaccgtgca ttactttaac gacatacatg gggatcacct
    33661 gcttttttct tttcattata cgaactactc gacacaatac aagaaaaatg cttagacggt
    33721 ctttattaag aatttacatc atccaaagaa gcgtacgctt ggaataactg atctaactcc
    33781 ggattgactt tgctcagctt cactaatcgt tgcgaatcag aaagtaaaaa acagtgttta
    33841 ctactgccag tagtttttaa ttttttgtct tcagttccca caatttcgta gctaaaatcc
    33901 aaccgtgtcc ccgtatactt ttggatagtt ggatggatgc tcactttttc tccgtaatgg
    33961 atcatttctt tatagctgca atttacttcc agaacgggga tgatgatccc agattcttcg
    34021 atttttttat agggaaaccc tagatgtacc aataaggcta cccgagcctc ttcaaaccag
    34081 cggatataat tgctgtgatg aataatcccc atttgatctg tttcataata aaaaggttct
    34141 cgcacataac ctgtaaattt ctccatgact catgcctcgt tttccattga ttttttacaa
    34201 aaataattca tccatttcgg aagtgcttcg ctgatttgtg tcggcaaaac aatatattgt
    34261 tcttttgcca gctggtctcc aatgaaacta tgaagataaa tagctgctgc aatcgtttgg
    34321 tcattttgag gaaactgggc taaaaatcct gtgatcatcc cagctaaagt gtcacccatg
    34381 ccgcccgttg ccatagcagc agaacctaaa ggattggtgt agaagtgctg gtgaccataa
    34441 atttttgtct catgactttt caaaacgagc acagcaccga tttcctgttg cttctttttg
    34501 ttttctttat cccgttgttc ttgtatcggt agagaactca accgttgcca ctccatttga
    34561 tgaggtgtaa gtacagtttg ttcgggatag ggtagcaaaa gatgattagc agcaagtaaa
    34621 cttaaagcag agccatcaat caccagccat tgttcttttg attggttttc tagtacttgt
    34681 ttgaaacgtt ccaaactctt agaagaagta cccaatccgg gaccaatcaa gagtacatct
    34741 gcttgcttta ttacggaaag aaactggtca gtatccgtcc aaactacaat cattgcttct
    34801 ggcagatgac tgtgaagagc actccgattt ttttcatcag ttactacagt cgtgagaccc
    34861 gctccgctgt gtacggcagc taaagcactc ataatgattg ctccgccata ttgttcattg
    34921 ccgccaatca aaacgatacg tccaaatgtt cctttatgtg aaatttttgg acgaggtgtg
    34981 atgactcttt tcactagttg ttcgtttatc agcatctaaa aacctccttt tactcattat
    35041 agcgtatatt ttttttagag aaaaacagat aagaaaagga attgtcagat tttttgaact
    35101 atttttttct gtaatttgtg gtatcatgaa cacgaagact taaataagtg gaggattaac
    35161 tttatgacaa ttgattggca aaaagaagta gaagcacgta aagaagactt gcttgaagac
    35221 ttgaaaaatc ttttacgtgt caacagcgag cgcgatgact caaaagtaac accagatgca
    35281 ccatttggac ctggacctcg cgacgcattg aaacatatgt tagcttatgg cgaacgtgat
    35341 ggatttaaag taaaaaatgt cgataactat gcagggcata ttgatcttgg cgaaggagac
    35401 gaaacgctag ggatatttgg acacatggat gtcgttcctg caggagatgg ctgggacaca
    35461 gatccttatg aaccagtaat caaggatgga aagatctttg cacgcggatc aagcgatgac
    35521 aaaggtccaa gtatggcagc ttactatgcg atgaagatca ttaaagaact tgacttgaaa
    35581 ctatcaaaaa aagttcgctt cgtagtcggc agcgatgaag aaagcggctg gggcgatatg
    35641 gcttattatt tcgaacatga agaagaacca gattttggtt tctcaccaga tgctgaattc
    35701 ccaatcatca atggtgaaaa aggaaatgtt tctttagctt tacgcttcaa aggcgacaat
    35761 gcaggagatt atgtcttgaa atcttttgtt tccggacttc gcgaaaatat ggtgccagga
    35821 acagcaactg cagcacttca agtaccaagt gcagatgcag ctatcgcgat ggaagaagca
    35881 ttttaccaat tcatcgaagc aaatccagta agcggaacga ttgaagcgga caatacgtat
    35941 gtaaaaatcg aattagttgg taaaggcgca catggtgcaa gcccacaatc tggtatcaat
    36001 gcaggttctt tcttggcatt gttcttagat aactatgaat tcctaggatc tgctaaacaa
    36061 tttatccatg tagcagctgc ttatgtccat gaagattttt atggagaaaa actaggagtc
    36121 gcttatgaag atgaaaaaat gggcaaattg acaatgaatg ctggactatt tgcttttgaa
    36181 gaaaatggta cagaggaagc gaacttcatc aatatgaatt tccgttttcc aaaaggtgta
    36241 acagtagacg gattgcaaag tgacatcgaa caaacagtgg ggcaagaagg cgcaacagtt
    36301 actcgaggtg ctcgcgtaat ggaaccacat tacgtaccaa tggatgatcc attggtggct
    36361 acattattgc aagtctatga agaccacact ggagaaaaag gctacgaaca aatcatcggt
    36421 ggcggaactt acggacgttt gttgaaacgt ggcgttgctt atggagcgat gttcccagga
    36481 tatactgata caatgcatca agcaaacgaa tttatgagtc ttgatgactt gttcagagca
    36541 acagcaatct atgcagatgc catctatcgt ttggcgaaat aattaattaa aaagaggatc
    36601 aagaattgca aattattttt gcagtcttga tccttttttt actttctact gtggtattca
    36661 tgataaacat gatatagatt caattcatat tctttcttag cgttcgtgac gactgtatcc
    36721 aaaatcaacc ctgttactaa tgaaagaagt gctaaagtca tcaatccagt acttaaaatc
    36781 gcagaaggga tgcgtgtaat aaagcttgtc agcatatatt cgcgaatcac aggaatcccc
    36841 gtgaccaatc caaataaaaa gaagaagatg gtccaaatcc caaagaaaag caaaggctta
    36901 taatctttaa acattttaat aatcatcatg atcactttga atccgtcaga gaatgtattc
    36961 aattttgatt cgctgccttc aggacgatca cgataatcga ttgggatttc aacgaacttg
    37021 aattttttat ctaaagcatg gatcgtcaat tccgtttcga tttgaaaacc agaactcata
    37081 ataggaaaac ttttgacaaa gatacgattg aatcctcgat agccggtcat gacatcaaga
    37141 atttttgttt tatacattct agtaattgta tttctaacaa ggttatttcc aaaatcgtgg
    37201 aaaggtctct tattctcatc aaagtaggtt ccatttgata ggcgatcacc aatgaccata
    37261 tctgcttcac cagaacgtaa tttctcgagc aaaccatgta cagcttctgc aggataagta
    37321 tcatcgccat ctaccattaa ataatagtcg gcatcgatat caaagaacat ttggcggatc
    37381 acatttcctt ttccttgacg aggttctttt tttacgattg ctccaccttg aacggccaat
    37441 tcgtatgttc gatcggtcga attattatca tagacataaa tatctgcttc tggtaattct
    37501 cgtttaaagt ctgcaatgac tgttgaaatt gttgcttcct cattgtaaca aggaatcaga
    37561 acagcaattt tttcttgttg ttccattttt cactctcctt aactatagaa aacaaaagct
    37621 aaattaaaaa tacctcataa tcaaaggaaa tgctagtttt tcccgctaaa tatcatttat
    37681 ttaaaaagaa aatactggaa tatatgtttg gaaagctcta tctaaaaaac cacccactac
    37741 aaaagaagga catgatacct ctcttttgaa tagtgggtgc gtattcgttc tctcactttt
    37801 ttgacgtatt aatctgttgc accttttttt cttgaaattt ctaatacggt tcctgtatga
    37861 gcatctgcta aaaattcata ataaacagtt tcgccatctt ctattcgaga aagacctccc
    37921 cgataagcac tcgaccgaac ggcgaatttc ctaataggtt ccttttcaaa agagatccaa
    37981 gaaccttcga ttgcaccttc ttttagaaaa gatgacttga tattttcaag tacttggtct
    38041 gctgacaata cttttttgcg atgataccaa atcgttgaag ctaccccgct caataatcct
    38101 agaccgattc caactgctaa cccgccttta aaatagctta gttcgctttc ttcatacatg
    38161 tggacatacc tccttcttct cacttgttac tccttgtgct tattttacca cactctcata
    38221 ttttctttga aataaataac cgctaccaga aaaaataagc tataataaat acgatcggtc
    38281 tgcagaaaaa atcatatttt atccgcagat caatataagt ctgagaggag tttagtctga
    38341 aatttagacg aatagcatat ggaagaaaaa acatttcaac gaatcaaaga gttaacagaa
    38401 ttacaaggaa caagcggttt tgaacaagat gttcgcgctt atatggaaag tcatatggaa
    38461 ccgctggtag atgagttaca gttagatggt ttgggcggca tttttggtct gcgccatcat
    38521 gaagaagcgg atgcaccccg tgtaatggtc gcagcacata tggatgaagt cggattcatg
    38581 ctgacacaaa tccaagaaaa cgggcttttt aaagtcgtac ctctaggcgg ctggaatcct
    38641 tacgttgttt ctgctcagcg ttttacactt aaaacctcta ctggtaagaa ttatccatgt
    38701 atttcttctt ccgttccccc acatttattg cgaggaacaa gcggacaaaa atcagtagaa
    38761 gtaaccgata ttttgttcga tgctgggttt gaatcaagag aagaggcaat gagttacggt
    38821 gtccttccag gagacacaat cgttccttac gctgaaacga tcaaaacagc caacggaaag
    38881 aatattatca gtaaatcatg ggacaaccgc tatggctgta caatggtatt agaagcttta
    38941 gaagcgttgc aaaatgaaac attaggtcat acattgattg caggcgcgaa tgtccaggaa
    39001 gaagtaggct tgcgtggttc taaagcttct gtcaataaat tcaagccaga tctgttcttt
    39061 gcagtagact gctctgcagc agatgataca gtgacgaaaa atggcacatt cggacattta
    39121 ggagaaggta cattgatgcg tatccaagat ccaggtttga tcatgcttcc tcgtttgcgc
    39181 gagtacttgc tggatatcgc tgaaacaaac aatatccctt atcaatactt tgtttcaaaa
    39241 ggcggtacag atgcaggtgc tgctcataca caaaacgaag gaatcccaag tacagtgatt
    39301 ggcgtagtgg gacgttatat ccatacgcat caaacgatgt tcagtattcg cgattttgaa
    39361 gctgcacgag aaatgttgat tcaaacactg aaaggtttgg ataaatcaac agtaaatacg
    39421 atcgtatacg gaaaataatg cgatagtgaa actataaaat ctggcaaaag attgcttttt
    39481 gccagatttt ttttataaaa agaggatcaa tgtttgttag ttcgaaagaa aggtgtataa
    39541 tttaattgaa aaatacataa acagaaagta gaggacaaag aatgattatc ccaaatagtt
    39601 tagaagaatt agcaggctac gtagaaactg gaaagagtgt atttttcttt actgccggct
    39661 ggtgcggaga ctgccgtttt atcaaaccgc aaatgcctga aattgaaaat gacttttctg
    39721 attggcaatt tattgaagta gaccgtgaca agtacataga tgtagccgct gaatggaaca
    39781 tttttggtat cccaagtttt gtcgtgatcc aagacggaaa agaattaggt cgtctagtga
    39841 ataaagatcg taaaacaaaa caggaaatcg aatcgttcct agaaagtgta acaaaaggct
    39901 gacatctgtt aggaggggtc aagatgaatc aagaatataa gaatatttta gtaggtatcg
    39961 acggtagtga acaagcactt gctgctttca aaaaagcggt agaagtggct cgccgtaata
    40021 atgggaaagt atatgtagca aacgtaatcg atcagcaatt ttataacttt atgggctatg
    40081 cacctattga tcaaaatcta gtcgatcagc aaactgaaac agccaaggaa atgatcgaag
    40141 aatgtaaaga atatgggaaa tctgttgatt acacaaatat agaaggaatt attgcatatg
    40201 gttctgttcg tgaatccatg gcagtcaaat tgccaaaaaa atatgagatc gatctaatca
    40261 tggttgggca gtcaggtcta aatgcagtcg aacgctttat gacaggaagt gtagccagct
    40321 acgtgatacg tcattcacct tgtgatgtct tgatcgtttc tgacgaagaa gaacagccaa
    40381 gtaattaagc aagtggaact tgtacgacct ttttaatcaa ttaactaaaa cagtaaaggg
    40441 actgtgacaa aagtcttgtc acagtccctt gttacgaata aatggtgttc cagaagaggc
    40501 ttcttcggaa ataaagcatg aaaaaaattt catgcagtga atgcaatttt ttgttaagat
    40561 aaatctcagc aaaggataat ggaggaaaga acatgatttt tgcttataac aaagcacacg
    40621 tcggagacac cttgatggtt attatagccg acgataaagg aacagaaaac actgttgaac
    40681 gcaaatggaa tgttgctcgg atcaaagatg aacaaggtca agttgttgct tggaactttt
    40741 tccatatctc cgatcatcta acaatcgaag ggaacggcca agtaagctta acagatgagg
    40801 aattagcgaa attgaatcga ttgatcaaag aagcaggatt cgaagaacag cttgaagctg
    40861 atcatgaacc gaagatcgtt gtcgggtacg taaaaacatg cgtcccacat cctgattctg
    40921 accatttatc gattactgag acagaagtag acaatggtac agtattgcaa atcgtttgcg
    40981 gtgcacccaa tatcgaagct ggacaaaaag ttgtcgttgc aaaaccagga gctatgatgc
    41041 cagatggaat gatgatctgg ccaggaactt tgcgaggggt agatagctat ggaatgatct
    41101 gttccgctcg tgaattgcat ttgccaaatg ctccagcaaa aaaaggaatc ttagtattgc
    41161 ctgaggatgc cgtagtcgga gaagcatttc caaaataaag aggttgtgac aagtctttgt
    41221 cacaacctct tttttattaa ttttcactat tttgattttg ttttaatgcc gattgatcga
    41281 tcgtcaattc aacagtagtt gttttttctt tcgagccttc atagtaagtg attttgacag
    41341 aatctcccac ttttttctta tacaaagcag attgaagttc tacaccagaa gaaacttctt
    41401 tgtcatcgat cttagtaatg acgtcgtatt gtttcaatcc agctttttca gccggtgtag
    41461 ctgtttggac atttgtcacg atgacaccgt tagttacaga tgaaggaatc ttcaagattt
    41521 gttcttgttg ctgagtagaa acggcagata agtcgaccat tgtgatacct agagctggac
    41581 gtgtcacttt tccgtctttt tccagttgat tgatgatatt cactacatcg ttacttggaa
    41641 tagcaaatcc cattccttct acgcttacat tagaagtaga ttcagaagta cttgcgatct
    41701 tacttgagtt gataccgata acttgtcctt cgatattaac taaaggacca ccagaatttc
    41761 cagggttgat tgctgcatct gtttggatcg cattgatatt gactgtttcg ttcgattcat
    41821 tcgtacttgt cacttgtcgg ttcaaggaag aaatgattcc tgaagtgaca gaatttgcat
    41881 attcagatcc tagtggggaa ccaatcgcaa tcgcaggctc accaaccttc agagcacttg
    41941 agtcaccaaa agaggcaact gtttcgactt tgtctgaatt gatcttcaac accgctaaat
    42001 ctgaataagc atctgttcca actaattcag cttttacctt cgtaccgtct ttcatcaaga
    42061 cttcaagacc ttgctggcca tctactacgt gattattcgt gactacataa gcagtattcc
    42121 cgtctttttt gtagatcacg ccgcttcctt cactataagc ttccaaatta ctatcatctg
    42181 agctgctact ttcttcttgc tgcccgaata gtccgccaaa accgcttgat tggttttgac
    42241 tttgtaagtt gataacagaa acgacagcgt cttgaacttt atctaccgct ttggtgatat
    42301 cagaatctac attgactttg acattttcca caactgtttc accggcagaa ttctgattgc
    42361 cgcttgtagc agtagaacta ttgttgccag tgcccatcgc tgcataaaaa atgccagctg
    42421 tcagtagtcc tccaacgatc cctccaacaa gccccagacc taacttacgc cagaggctat
    42481 tatttttact ttttttcatc tttggtgtca cattttttct atccatgtgt tcctcctcca
    42541 attacattca tttatctact gttagtatag tcttatttgt tgactttagt ctactttgag
    42601 actgtgaact ttttatgaaa aactttagga aaaatcattg ttttcagatg aaaatatttg
    42661 attttctttt tccacagata ctgtgtaaaa ctacgcggat aggattggaa aaataaggga
    42721 taaaacatat ccacagcctg tgtataaagt ggataaattc ttataaaacg tatgtttgcc
    42781 taatgaatgt gatgaaataa ggtaaaataa cactgttttc tgtggataaa cctgtggatg
    42841 ttgtgcataa ctgttgggga aatcttttta acaaaaatag ccaaaataaa catatagacg
    42901 aaaaaattga ttataataaa caaagtgagc atgaagacca aaggagagaa aacatgaata
    42961 tcaaaattat ctcagtagga aaattaaaag aaaaatacct gatccaaggt atcaatgagt
    43021 atgtcaaacg gctgaatgcc tatgcaaaaa tcgaattgat cgaagttcct gacgaaaaag
    43081 ccccggagaa tttaagcgaa gcgcaaatga gacaagtaaa agaaaaagaa ggggaacgga
    43141 tcttagcgaa aatcaaagaa caagaatacg tctatgcctt agcaattgaa gggaaaaatc
    43201 ctacaagtga atcttttgct aaacaaatcg accaattagg tatccaagga aaaagccacc
    43261 ttgtttttgt tatcggcggc tctttaggac tcagcgaagc cgtcatgaaa agaagcaatg
    43321 ctcagatctc ttttggaaaa atgacgtatc cacatcaatt gatgcgtctg atccttgtcg
    43381 agcaaatcta ccgtgccttc cggatcaatg cgggggctcc ataccacaaa taatgatatt
    43441 ttttaagaga aaaaattatc cctattttaa ataatagcaa taggtagtgg tagggagaaa
    43501 tttataaata acttttttat ttgctttggt agccaagtaa gttgcaaaag aaaaatagat
    43561 actgttaaaa agataatgta gacatagaaa caaatacgta aaattttagt tagaataatg
    43621 gcaaggagaa aaaacatgat agatgaaaaa aagtgtttaa aaaatctatt agaggatatg
    43681 gatgatattg aagaaaacta tctaaatgga ctgggaaaac aaatatattt cagatactta
    43741 agctatctaa aaatgaaata agacatagta attttttagc ttttttgttt gctccaaatg
    43801 aaacccacaa tttatctgat gagtttttta aaatgttttt gaaaaggtat atagattcta
    43861 atgatgatac caaagctgct atcaattatt ttgatgcttt acttaatagc tatgaagatt
    43921 taattgttta cagagaaaat aagaatattg atattttatt ggtatcggaa aaaaataaaa
    43981 tagtggtgtg catcgaaaat aaaattctgt cttcggagtc tggagggcaa cttaataaat
    44041 accaaatata tatagaacgc aattattcta actataaaaa aatttttgtt tttttaactc
    44101 cagatggaaa tgaacccaca aatcctagtt ggggcataat tacttacaag aatatcgttg
    44161 aagagagtgt aaaatatttt gtgtaaatag aaaaaaggaa gtcccttctg tagaatagag
    44221 ttaccacaac acattcacag aaaagaggac ttccatatga acgattttac tacagaaatt
    44281 atggaaatac taatcaataa aggtgatttg gatgatttgt ttcgtcgtca cctagaattg
    44341 gctattaacg ctttattaca agctgaatta acggtatttc ttgactatga aaagtatgat
    44401 agagctggat ttaattcagg taattcccgt aatgggaatt attcgcgctc ttttaaaaca
    44461 gagtacggtg aattgaattt agtaatacct agagatagga atggagactt ttctcaacaa
    44521 actttacctg cttataaaag aaccaatgac tctttagaaa ccactattat tcagctagtt
    44581 caaaaaggaa ttactatgtc cgaaatctct gatctaatcg aaaaaatgta tggtcattat
    44641 tacaaaccac aaactatttc aaatatgagt aaaattgtgt ctgaagatgt ttcggcattt
    44701 aaagaaagaa ctttagaagc taaatactca gtcattttta tggatgctac tcatattccc
    44761 ttaaaaagac aaaccgtatc aaaagaagct gtctatatag taattggtat caggttggat
    44821 ggaactaaag aggttctagg atttactata gctccaactg aatctgctta tgtttggaaa
    44881 gagattcttc aagatctaaa agaccgtggt ttagaagagg ttttgttagt cgtaacagat
    44941 ggtttaagtg gtattgacga tagtattcat agtgtttatc caaatgctca atttcaacaa
    45001 tgttgtgtcc atatatctag aaatatcgct cataaggttc gtgttagtga tcgacaagaa
    45061 atctgtagcg atttcaaatt agtttaccaa gcaagttcaa aagaagaagc aaataatcaa
    45121 ataaggttta tgatagataa atggaaaaag cagtatccac gagtggttaa attgctcatg
    45181 aatcctgcta tattaacctt ttataatttc cctccgtcaa tcagaagaac tatttattca
    45241 actaatttga ttgaaggttt taacaaacaa ttaaagaaat ataccaaaag aaaagagcaa
    45301 tttcctaatg aagaatctct ggagagattt ctagtatctc aattcaacaa ctataatcaa
    45361 aagtttctat gccgagttca taaaggtttt aaagaaatac atgatacatt agaatcaatg
    45421 ttttaacttg atcaacagaa tgggcttttc catttacaca taattattga cacaacctat
    45481 tctggaaact tacaaataaa agcttat
//
LOCUS       DADQCX010000012        43260 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.012, whole genome shotgun sequence.
ACCESSION   DADQCX010000012 DADQCX010000000
VERSION     DADQCX010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.012"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(54..788)
                     /locus_tag="J8R83_000615"
     CDS             complement(54..788)
                     /locus_tag="J8R83_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAZ9573770.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="J8R83_000616"
     CDS             1115..1525
                     /locus_tag="J8R83_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAZ9573771.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="J8R83_000617"
     CDS             1518..2219
                     /locus_tag="J8R83_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAZ9573772.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="J8R83_000618"
     CDS             2219..3805
                     /locus_tag="J8R83_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9573773.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="J8R83_000619"
     CDS             3824..4045
                     /locus_tag="J8R83_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAZ9573774.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="J8R83_000620"
     CDS             4042..4803
                     /locus_tag="J8R83_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAZ9573775.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="J8R83_000621"
     CDS             5183..5692
                     /locus_tag="J8R83_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAZ9573776.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="J8R83_000622"
     CDS             complement(5767..6306)
                     /locus_tag="J8R83_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAZ9573777.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="J8R83_000623"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="J8R83_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAZ9573778.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7373..8170
                     /locus_tag="J8R83_000624"
     CDS             7373..8170
                     /locus_tag="J8R83_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAZ9573779.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8198..8833
                     /locus_tag="J8R83_000625"
     CDS             8198..8833
                     /locus_tag="J8R83_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAZ9573780.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="J8R83_000626"
     CDS             8853..9626
                     /locus_tag="J8R83_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9573781.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="J8R83_000627"
     CDS             10034..10831
                     /locus_tag="J8R83_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAZ9573782.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="J8R83_000628"
     CDS             10809..11222
                     /locus_tag="J8R83_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573783.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="J8R83_000629"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="J8R83_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAZ9573784.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="J8R83_000630"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="J8R83_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAZ9573785.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="J8R83_000631"
     CDS             15999..16559
                     /locus_tag="J8R83_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAZ9573786.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="J8R83_000632"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="J8R83_000632"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAZ9573787.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="J8R83_000633"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="J8R83_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAZ9573788.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="J8R83_000634"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="J8R83_000634"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAZ9573789.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="J8R83_000635"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="J8R83_000635"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAZ9573790.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="J8R83_000636"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="J8R83_000636"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAZ9573791.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="J8R83_000637"
     CDS             21906..22484
                     /locus_tag="J8R83_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAZ9573792.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="J8R83_000638"
     CDS             22536..23018
                     /locus_tag="J8R83_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAZ9573793.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="J8R83_000639"
     CDS             23135..23509
                     /locus_tag="J8R83_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573794.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24187..25539)
                     /gene="brnQ"
                     /locus_tag="J8R83_000640"
     CDS             complement(24187..25539)
                     /gene="brnQ"
                     /locus_tag="J8R83_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAZ9573795.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25686..26276
                     /locus_tag="J8R83_000641"
     CDS             25686..26276
                     /locus_tag="J8R83_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAZ9573796.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26404..27753)
                     /locus_tag="J8R83_000642"
     CDS             complement(26404..27753)
                     /locus_tag="J8R83_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9573797.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27921..28661)
                     /locus_tag="J8R83_000643"
     CDS             complement(27921..28661)
                     /locus_tag="J8R83_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573798.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28674..30266)
                     /locus_tag="J8R83_000644"
     CDS             complement(28674..30266)
                     /locus_tag="J8R83_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9573799.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(30834..31130)
                     /locus_tag="J8R83_000645"
     CDS             complement(30834..31130)
                     /locus_tag="J8R83_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573800.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31306..32031
                     /locus_tag="J8R83_000646"
     CDS             31306..32031
                     /locus_tag="J8R83_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAZ9573801.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32024..32866
                     /locus_tag="J8R83_000647"
     CDS             32024..32866
                     /locus_tag="J8R83_000647"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAZ9573802.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32869..33390
                     /locus_tag="J8R83_000648"
     CDS             32869..33390
                     /locus_tag="J8R83_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAZ9573803.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33643..34206)
                     /locus_tag="J8R83_000649"
     CDS             complement(33643..34206)
                     /locus_tag="J8R83_000649"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAZ9573804.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34457..34726
                     /gene="rpsO"
                     /locus_tag="J8R83_000650"
     CDS             34457..34726
                     /gene="rpsO"
                     /locus_tag="J8R83_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAZ9573805.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34914..37040
                     /gene="pnp"
                     /locus_tag="J8R83_000651"
     CDS             34914..37040
                     /gene="pnp"
                     /locus_tag="J8R83_000651"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAZ9573806.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37550..37816
                     /locus_tag="J8R83_000652"
     CDS             37550..37816
                     /locus_tag="J8R83_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9573807.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37960..39951
                     /locus_tag="J8R83_000653"
     CDS             37960..39951
                     /locus_tag="J8R83_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAZ9573808.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40305..41606
                     /locus_tag="J8R83_000654"
     CDS             40305..41606
                     /locus_tag="J8R83_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAZ9573809.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41736..43106)
                     /locus_tag="J8R83_000655"
     CDS             complement(41736..43106)
                     /locus_tag="J8R83_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAZ9573810.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
BASE COUNT        13996 a         8028 c         9041 g        12195 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcacagcat gacagcattg
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc actagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagtttt tttgcgaaaa ctatttttat atcatatata tgtctaaaat ctatattata
    23881 aaagaaatgt tgtttgatca gcttctcttc ggtattagtt caaaacaaaa cggcaaagta
    23941 tatggagcta ctttgccgtt ttgtttctct aatactcagg tcagtttata gacgctcaat
    24001 aaacggtgtt caaaagccag tttctcggta ttaagtcaaa tttatgcaaa aatgtgagaa
    24061 gccattttca aaaaatattt cttaatactc gaaactgagc ggctttttca cgacctctca
    24121 ataaacagtg ttcaagagac agcctatcgg caataaggct gaacgtctct ttcacaacct
    24181 cttttatcaa tctgctactt cttctttctt agcgaaactc caaatcagtc cgataacaaa
    24241 accgataact gctggtacga tccaccccat ccccaatttg aaaaacggca agtagctttc
    24301 cgcaacatat aaaagatttt gaacaatagg tgtttgtttg atagtttctg ggcaagcgtt
    24361 caacccatca aaaatcgaag caatcaatgt aaaataagta gtcattcgat aaacagccgt
    24421 acgctgctta aacaaaggac caactaacac tagtaaaatc agtgtcattg ctaatggata
    24481 gatgaacatc aaaacaggca acgaaaattg aatgatattc gtcaagccta cgtttgccgc
    24541 taaacaagga aggatactag caagtgcaac aaagaatgcg taatttcttt gcggaaacaa
    24601 atctgtgaat gtttctgcaa aagctgtaat caaaccaata ccggtcttca agcaagctaa
    24661 tataacgata aatgctaata agatactgcc ataagtacct aaataatgat cagcaatctg
    24721 agccagcgtg atcccgccat tttcacttag agcaaagcta cctaagctca tagcacctaa
    24781 ataagcgagc aaagtataaa tgattcccat caatataatg ctgatcgcac cagatttgat
    24841 cgtgtcttta gcgatttcag caggttttgt tacacccatg ttttggattg ttgtgacaat
    24901 gatgatccca aatgctaaag cagcaagcgc atctaatgtg ttatatcctt gagtaaaccc
    24961 tgtgaaaaaa gcatgctctt gataatttgg ctgaataggc gcttgattta cagaacctag
    25021 tggattcaaa aaagcaagga gaagcaaagc acctaataaa accaaaaatg caggattcag
    25081 gaactttcca acataatcta atatctttgt cggttttctt gaaaaccacc aagccagcac
    25141 aaaaaataca atactgaaaa ttgctagata tagcgtctgt ctgctaggat cgataaatgg
    25201 tgctaaacca atctcgaaag atgtggttgc aaggcgaggt aaagcaaaaa acggtccgat
    25261 aactaagtaa agcaagatgg taaaaaccat cgcatatgtt tgatttatcc gttttgctaa
    25321 ttcatataca cctgagcttt tcgatacacc aatggcaatc acccctaaga agggaagacc
    25381 gataccggta accaagaaac ctagattcgc ccaaaaggta gcagcgcctg cttcttgacc
    25441 caaatgaacg ggaaagataa gatttccagc accaaaaaat agaccgaaaa gcatggagcc
    25501 tataaaaaga tagtctttaa atgataattt ttttgtcata cataactcct ttacggtttt
    25561 tttaaaagta acaaaatttc gaaaaatatg caacaatttt cagaaaattt cctatataaa
    25621 acgacggtta tttaataacg taagtgataa aataaaagcg ctgaatcatc tgaggaggaa
    25681 tcatcgtgac aaagtcgaga ttagaagcat ttactgatgg agtggtagcc attgttttga
    25741 gagttcttgt attagagatc aagatcccta atacatctag ctttcattct ttatgggtca
    25801 tccgaaatac attattagct tataccatca gctttatatt tgttgcggtg atctgggtga
    25861 accatcatcg tatatttcag atggcagaac gaattaatta ccgagtggtc tggtcgaata
    25921 tctttttgct cttttggctg actttatgtc cttctgttac tagttgggtc gggcgtaacc
    25981 ctgaagcttt ttggcctgag atggcttatg tcttagtata cacgatgtgg agtttttctt
    26041 ttggtatctt gatgaggcaa atcatgaaag caaataaacc agattcccat gtcgtgagag
    26101 ttttgtcaaa ggaccgtcga agtcttatct ccatgatgat taacttatgc ttgattgccg
    26161 gtgtcttttt tgtaccgttg atcgggttat tcggacgttt ttttgtatct ggtatttgga
    26221 ttttttccta taaaaaagca gatgcctatt atcagcggtt gtttccgggg aaatagaaaa
    26281 gaggctggga cagaagcttt taactccaag aaataagccg aaatttcaca aaaatttaag
    26341 aagcaatttt cgtaaattcc ttcttatttc tcgaagctga ccacttctgt cacaactact
    26401 ttcttacttc ttacgttcat atttcatatg atagattagt aatagaagca agaaccacac
    26461 aggtgttagt aataaagcga ttctcgtatc ttttcctagg aacaagacga cacacacaaa
    26521 ggccatgtaa agaaatacca gataattact aaatgggtac aacggcattt taaatgaatg
    26581 agcttttttg ccgaggatac ttttacgata tttcatgtgc gtgtagacaa gcatactcca
    26641 gataaacaag aaacaagtag tggcaatact gcttactagt gtgaatactt cactaggcat
    26701 cacgtaattc aagataacag aaatgaaaat gacgatagta gaaaatgtca aagcattccc
    26761 tggcacatga tgtgttgtta actttttgaa ttttttaggg gcactgcctt cttgcgctaa
    26821 agaacgaagc atacgtcctg tactatatat tgcactgttg caggcagaag ctgctgcact
    26881 taatacgact aaattgatca aggaagcagc aatcgtgatc ccaatttccg aaaatacttc
    26941 tacaaatgga ctgttatctg gattcaagct gttccatgga tagattgcca taatgacaaa
    27001 aagagatcct aagtaaaata agatgatcct gataggaata ttattgatag cttccggcaa
    27061 cactttttca ggattttctg tttctccagc gactaatcca actaattcta tcccagcaaa
    27121 agcaaaggtt accatttgga aagctaagat aaatcctttt gcaccagttg gaaagaatcc
    27181 gccatgagac catagattcg tgatactggc tgtgccaata tctgtcgtat agtgggtgag
    27241 gatcatataa gctcctacga ggataaaggc aatgatcgct acaactttga tcaatgcaaa
    27301 ccaaaactct aactcaccaa acaatgagac agccaccata ttcaagcaaa gaagaagacc
    27361 taatgcaatc agttcaggaa gccactgagg aacaccaggc gcccagtagc gtacatacat
    27421 tccgatggct gttaaatcgg ccattgcaat cgatacccag cagaaccaat acgtccagcc
    27481 agtgatgaaa gccgcttttt tgccaagata ttctgcaaca aaatccagaa aagaatggtt
    27541 attggtgttt gataacagaa gttcgcctaa cgcacgcata atgaaaaaac agatgcatcc
    27601 agtaataaga taggcgagca atatcgaagg gccagctagc tggatagact ttccggaacc
    27661 taaaaacaac cccgttccaa tcgctccgcc aatagaaatc agttggacat gtctattttt
    27721 cagtccacgc tgcagttctt gctcttcatt catttttaaa tcatcctaac taaaaaagtt
    27781 taattacttc catattaaaa gagttttctg aaaaacacaa ctaagattcc aaaattttca
    27841 gaaatttacc ttttatgagt aattcataaa aaagaactgc ggtaaacacc gcagctcttt
    27901 gtcccaatca gctattgatc ctaagcattt aaaatacgtg aaaggaattc ttttgtacgt
    27961 tcttctttcg gatggacaaa gatatcttct ggtgtacctt cttctgcaat cacaccttta
    28021 tccataaaaa tgacacggtc agatacatct tttgcaaatt ccatctcatg cgtcacgata
    28081 agcattgtca agccagtatg tgctaagtct ttgatcgtat taagcacttc gccaaccatt
    28141 tcagggtcta acgccgaagt aggttcgtcg aatagcaata catctggatt cattgataat
    28201 gcccgagcaa ttgcgacacg ctgtttctgt ccaccagata attgtgctgg tttggcttcg
    28261 atataacgat ccataccaac tttttccaga ttttcgattg ctactttttt ggcagtttct
    28321 ttatctcgtt tcaggacagt tgtttgacca gacatacagt tttccaagac attcatattg
    28381 ttgaacaggt tgaaggattg gaaaaccata cctagattcg ttcgatattt aggtaaatta
    28441 tatttaggag ctaatacatt ttctccatta taaatgatct cgccgcctgt tggtttttcc
    28501 agtaaattga tacagcgcaa gaaagtagat ttaccagaac cggaagaacc gatgatcgtc
    28561 acaacttcac ctttattgac tgttacgctg atatctttca atacttcatt ttcaccgaag
    28621 ctttttctta gatgtttgat ttcaataatt ttttcattca tgattcttcc tccttattcc
    28681 tgcaaatttg aattgtcgat ttcttcaagc ttggtataag ctgaaggacc atcgattttc
    28741 ttttctaccg cccgcaggat tctggtgatc gtaaaggtca tgactaagta gatgatcccg
    28801 acgatcgtaa atgtttggaa gaattggaaa ttcgcaccgg aagcagagtt tccttggaag
    28861 aacaaatcag ctacgccgat tacacttaaa actgctgtat ctttgatatt gataacaaac
    28921 tcatttcctg ttgctggcaa gatattccgt aaaacttgtg gaataacaac ttttctcatc
    28981 gtttggccat gggtcatacc aatggcttgc gcagcttcga actgcccttc atctactgca
    29041 aaaatccccc cacgaacgat ctctgtcatg taagctccag tattgagaga gacaataaac
    29101 aaagcggcaa tcgttcggtt caatgaaatg ccaaaagcga gtgccagacc gtagaagatg
    29161 accattgctt gtaccatcat cggtgttccg cggaatactt cgacatagat agaaagaagt
    29221 gcatttccga ttttttggaa gaagcgagtc agtgcatttc ctgattcagg taccgaacgg
    29281 aagacaccaa tcagtaatcc aagtgtagta ccgacaactg tcccgatcaa tgcgatgaac
    29341 aaggtaagtc cagcacctcg taagaacata ttgccgtatt gtttccaaat cgtagtgaaa
    29401 tcagaaatga tgccaggttt ttcttcacta tcagttgcag caggctgatc tttgactgct
    29461 tggtccataa ttttggttcg ttcatcgtta gagatgccag aaagaatctg gtttactttt
    29521 tggatatccg ggtcgccttt acgcatacca acagaaatct gaacatcttc cgggtttgtc
    29581 tggaagccat ctgcaccgct gaattcaagc atttccaagt ctttgttcac actagttgcc
    29641 gttacacctt ccggacgttc gctgacataa ccatcgatca ttccagaagc taaagctgtt
    29701 ctcattgctg agaaattatc cattgcttgt tgtttctgca catctggtat ctgatcgatc
    29761 acagtatagt ggaatgtatt taactgagca gtaatctttg ctccagaaag atctgctaaa
    29821 ctttttgctt ttgcatattt gctatctttt tgaactacta ctactaattg tgattcgtaa
    29881 taaggatcgg taaaatcaat ttcttttcgt cgttcagcag tagggctcat tccggcgatg
    29941 atcgcgtcga tcttgcctga ttgaagggca ggagccagac catcccattt cgtttggacg
    30001 atgactaatt ttttccctaa accatctgct acttttttag cgatttgaac atcataaccg
    30061 ccggcgtaac tattttggcc ttgaattggc aaggcattat tctcatctgt ttgttgagac
    30121 cagttgaagg gtgcataccc agcctccata cctacgcgaa actcatcgct cggtgttttt
    30181 tcatctgcat ttgccagaga tcccacactg aatagtgaga agacaaaagc aaatagtacg
    30241 gcaactgaaa ccatattttt tttcattttt ttctcccttt ctgattatat gatacacgag
    30301 cggtctagat gaaatgcggt aaagctttat ctgaaaaaat aaaaagcgac cgatttatag
    30361 atataaaaag gccgctaaaa ttccataagg tgataaacct ctcacaaaac atagcgcaac
    30421 ttagcatcac tgctaagaca gtccgcaagc tcttaacttg cgtcccaaca tacactccaa
    30481 gcaaaaaagt gcacatttcg gcgatcctcc ctattcctgc ttctccatgt ttgcttcact
    30541 ccacagggtt aatgattctc gcgacctcta cctcattgat tgaggcatct cgtattcagt
    30601 tatttataca aaaaaagttt acgatactcg agaggctttg tcaatctata actgctgttt
    30661 tttgaaaaaa tactgataaa tatagaaatc tttactttta ccgaaaaaac aatcaaaatg
    30721 tgaatcatct atccattgca aacgatagta taattataca caaaaatgta tgtaatacaa
    30781 taaaaaaaga actagaacag aaaatttcct gtgtccagtt ccatctcgat catttaagct
    30841 gccgctttct ttggctcacg tcctaggatc gcttgcaaaa gaacaacgac gccataaatg
    30901 gctaatatta gataaatcaa acttgagtat tgggtgattc cccagcccca tgttcgatat
    30961 acggctaatg taatggctaa aacaattgcg gcaatcacgt tgaataaagc aaaagcccaa
    31021 agatttccat tttctttgcg tacaagataa aaaacagaga aataaacgct taacgctaac
    31081 caggcgatac aagccagaat aacgccccaa taaataaaga atggtaacat atcgattcac
    31141 ctcactttta tacagcagta ttgtaacacg ttttcattct tttgtcagtg aacattgtga
    31201 taaattgttc aaatgcccat aacacttttt tattcccatt tttctgactt ttcaacaata
    31261 aatttgttcg agtatgggct ataatggaaa gtgaggtgac aaaacatgaa acaattaaca
    31321 gtagacgaag cagcaaaaga gatattagct tatcagcaaa ttacattttt gaccggtgca
    31381 ggggtatcca caccttctgg agtgccagac tatcgatctt tgtcaggaat ctaccacggg
    31441 atggagcagc cggaatactt gctgagtcat caagcaatgg tgaatgaacc ggataaattc
    31501 tatcaatttg tcaaaaagat ttatcatcct gaagcaaaac ccaatatcat tcatttggaa
    31561 atggcacatc tagcgaaaga aaaaaatgtt tgggttgttt cccaaaacat cgacggtttg
    31621 cacgcaaagg ctaaaagccc gcaactcgtc aattttcatg gaagtttgta tcaatgtcat
    31681 tgtcgaaaat gtcaacaaac ggtagactgg aaagaatatc ttcacagcga caaacatcaa
    31741 gcatgcggag gacaaatacg cccagacatc gtgttatatg gtgaagggtt tcaagatgga
    31801 gtcatggagc aggcggctta tgccgtcagc caagcagagc tgatcgtcat tgttggaacg
    31861 agttttcaag ttcatccgtt ttgtgatctg gtacagtttc gccagccgtc agccaaaatc
    31921 ttagtaatca atcaaacgcc tgtttattta gcggagcctt atacgtttat tcaagaagac
    31981 ggagcggttg ttttcaaaaa aatacaagaa ttaggagcag attatgactg aattcaaaac
    32041 cgaaaaagaa aaaatgattg caggcgagct ttattttgcc aatgatcctg agctggttgc
    32101 cgaccgtatg tttgcaagaa gtcaaagcca aatcatcaac caagcagaat cagcggaact
    32161 gcgatcccaa ttgttgaaag agacttttgg ccgtacaggg aaaaaaatct atatggagcc
    32221 agttatcaat tttgattacg gatataatat atttgttggg gagaattttt atgcaaattt
    32281 caattgtaca tttttagatg tcagcacgat tgaaatcggt gataactgca tgttcgctcc
    32341 gaatgtccag ctttacacgg cgacgcatcc actacatcca gtgaaacgta acagcggtct
    32401 ggagtacgca aaacccatta aaatcggtaa taatgtttgg ttaggcggag gagttatcgt
    32461 cacgccgggt gtcactctag gggacaacgt agtagtcggc gcaggttcgg ttgtgaccaa
    32521 atcttttccc gacaatgtag tgattgcagg aaatcctgct cgtatcatca agacagtaga
    32581 ggaagaacta acagaagagt ctcttgaaac attacgtcat aagatcgata tgatcgatcg
    32641 agagttgatt gctttattag aaaaaagaat ggatacggta actaaaatag gacaagtgaa
    32701 aaaagaagaa aaccaagcag tttatgatgc aaaaagagag cagcaagtat tggataaagt
    32761 tgttagtctg ctgaaaaata agggatataa ggaaacaata acagatacgt atgttgattt
    32821 gatgaaacac tcgcgcgaat accaaaacaa aatgaaggag gaataagtgt gatcgaagga
    32881 gagacacggc gaaaacaaat catgcaaacc ttggcaaata cagaaaaacc agtgagtgct
    32941 agcaagtttg cgaaaacttt tggagtcagc cgtcagatca ttgtaggcga tattgcttta
    33001 ctacgagctg caggtaaaag tatcgtggca acagcaagag gttatatcct cgaaacagaa
    33061 gaaaccaata ctgggcacat cagtaaaatc gctgtccagc atggaaaaga tcaaacagaa
    33121 gaagaactga gactaatcgt tgaaaatggt ggtgaaatca ttgatgtaat tgtggaacat
    33181 cccctttacg gtgagttagc aggaactttg cacatcaaaa cgccacaaga tatcgattcc
    33241 tttatgagac gttatcaaaa aagtaatgct actttgttat ccgaattaac aggcggcatc
    33301 catctgcata cgatccgcta cccagaaaag catatgctga aaaacatcaa acaaaaacta
    33361 gctgaagcag gaatcctcta cgaaggataa catcgtagct gctacttttt atcctagaaa
    33421 ctattctatc atctctgaga taaacaccca tatggaagaa ataagaaaaa ataagaaaag
    33481 atgcgtatcc aatacacaga attttttgga attgcgattt ctagatgtct atctaaattt
    33541 cgattagtgg agaaacataa aaaagggaag tgcagctttt gagcactccc cttttttata
    33601 aagctttctt gtagcatagt atcgaaggaa cctgccaatt ctctactcga tcaccaatac
    33661 gccttctttt agtgcaaatg gattttgatc gttgatgtgg tcatagaaca tcacaccgtt
    33721 gatatggtcg atttcatgtt gaacgacgat cgattcataa ttcttcaaac gaatcttgtg
    33781 tttttcacca ttcatatcat aataagacac agtgattttg gcatggcgaa caacatatcc
    33841 tggtacttct cgatcaacag ataaacagcc ttcaccttcc cctaaacaag catcttgaac
    33901 agaatggctc aaaattttag gattatacat aacagtactt agagaaggtc catctgcctc
    33961 tgggtcagga cttggtacgt gaacagcaat gattctttta gaaatatcta attgaggagc
    34021 agctaagcca acaccgcctc gtaagtgtag ttcttcagct ttgattggat cttggctgtt
    34081 ttttaagaac tcaagcatct cttttcctaa agagatatct tcttcgctta atggaagaga
    34141 aacttctttt gcaacttcgc gtaaggtcgg atttccttca cgaatgatat catccattgt
    34201 aatcatggaa tatgtacccc tttcttaaaa gactgtgttt caagtctatt ttcgcattat
    34261 agtttaccac aaaaatggaa aagtagtagt aagattgttt gaaaactacc ttttcttaat
    34321 gattaactac ttgattttca acccggtttc aggtaaagta tagctgtgtg ctctaggcac
    34381 atgacctgcc acttggttaa gcgaatcacc aacgttttac tcagtcgcag gggaataatc
    34441 gaaagaggtg aaagaaatgg caatttcaaa agaacgcaag aatgaaatca tcaacgaata
    34501 cgctcgccat gaaggggata ctggttctcc agaagtacaa atcgctgtat taactgaaga
    34561 aatcaaccac ttgaatgaac atgcacgcgt gcacaaaaaa gaccatcatt cataccgcgg
    34621 cctaatgaaa aaagttggtc accgccgtaa cttgttagct tacttacgta aaactgacgt
    34681 tcaacgttac cgcgaattga tcaaacgttt aggcttgcgt cgttaatttt agtcaaaaag
    34741 agtgggattc acatgaatct cacttttttt actcgtatat caattaagta aaattccgtg
    34801 atcaagctag atggactcct actaaccaaa tgaaagctgc tcaaaagacg gctttcggca
    34861 gttttcattt gtttagtagc gtcttgcttt cacgagaagg aaaaggagaa gttatgtcag
    34921 aaaaacaagt attcaaaacg acatggggcg gccgtccctt acaaatcgaa gtcggtcagc
    34981 tagcaaaaca agcaaacgga gccgttttag tccgttatgg agatacagta gtcttaagtg
    35041 cagctgtggc ctctaaagaa gcaaaagata cagacttttt cccattaacg atcaattatg
    35101 aagaaaaaat gtatgcagca gggaaaatcc ctggaggttt catcaaacga gaaggccgtc
    35161 caagtacgga agcaacattg actgcccgtt tgatcgaccg tccaattcgc ccgatgtttg
    35221 cagaaggctt ccgtaatgaa gtccaagtaa cgaacatcgt gatgagtgta gaaacagact
    35281 gctcgccagc tatggcagca atgctaggtt cttctttagc actatcaatc tcagatatcc
    35341 catttgacgg cccaatcgca ggcgtagaag ttggtcgtgt aaatggcgag tacgtcttga
    35401 atccaacagt agaacaagca gaacaaacag atatcgaatt gactgttgcc ggaacgaaac
    35461 aagccatcaa tatggttgaa agcggcgcga aagaagtttc agaagaagac atgcttggtg
    35521 cattgctgtt tggttttgac gctatcaaag agttagttgc tttccaagaa gaaatcgttc
    35581 aagcagtagg gaaagaaaaa atggaagtga ctttactgca agttgatgaa gtattgaaaa
    35641 aagaaatctt tgatgcttct tacgctacaa tgaaagcagc agtaatgact gaagaaaaac
    35701 ttgctcgcga agataatatc gagcaggtga agatcgatat ccgcgaagct tatgctgaga
    35761 aatttgcagg tcatgaagat gaagatcact tgttgaaaga agttaaacaa atcacagaag
    35821 atcttgaaaa agatgtcgta cgtgaattga tcaccatcga taagatccgt cctgacgggc
    35881 gtaaattgga tgaaatccgt ccattgtcat cagaggtcag cttattgcca cgtgtacatg
    35941 gatcaggttt gttcacacga ggacaaacac aagctttatc agcttgtaca ctcgcacctc
    36001 taggagagca ccaaatcatt gatggtttag gggtggaagt cagcaaacga ttcatccacc
    36061 actacaattt ccctcaattt tctgttggtt ctacaggacg tgcaggctct ccagggcgtc
    36121 gggaaatcgg acatggcgca ttaggtgaac gtgcgttagc acaagtaatc ccttcagaag
    36181 aagaatttcc ttatacgatc cgtttagtag cagaagtatt ggaatcaaat ggttcttctt
    36241 cccaagcaag tatctgtgct ggcacattag cattgatgga tgcaggtgta ccaatcaaag
    36301 cgccagtcgc cggtattgcg atgggacttg tttctgatgg tgaaaactat acgatcctaa
    36361 ctgatatcca agggctggaa gatcatcttg gcgatatgga ctttaaagtt gccggtacaa
    36421 aagatggtat cactgcttta cagatggata tcaagattca aggaatcaca gaacaaatcc
    36481 taactgaagc attaactcaa gcaaaacaag cacgtatgga aatcttagaa gaattgactt
    36541 caacgattgc tgctccacgt gaagaattaa gccaatatgc accaaaaatc gaaatgatcc
    36601 agatcgaacc tgctaaaatc aaagatgtta tcggtaaagg cggcgatacg atcaacggaa
    36661 tcatcgatga aactggtgtg aaaatcgata tcgatcaaga tggaaaagta agtattgctt
    36721 cagctgatgc agaaatgatc aaaaaagcta tcaagatcat cgaagatttg accaaagaag
    36781 tcaaagttgg tgaagtttat ctagggaaag ttgtccgtat cgaaaaattc ggtgcattcg
    36841 tcaacttgat caaaggaaaa gatggacttg tccatatttc ccaattagca aacgatcgtg
    36901 tcaataaagt cgaagatgtt gttaaactag gtgatgagat ccttgtgaaa gtaactgaaa
    36961 tcgataaaca aggacgcgta aatctgtcaa gaaaagcaat gttgaacgaa gatggttcaa
    37021 cgaaaaatga agaaaaataa tttaattcat aggaataatg tacttgtgat cgtgaaggtg
    37081 acagggggac aataattatt cgaaaaaagg ggactgtgac aaaagccgtg tcacagtcct
    37141 tttttttcga ataaacggtg ttcaaaagct tgcatctgcg gtaataagtc cagccaagtt
    37201 aaaaacatta ggagctgttt ttatttggct gttcttatta cttgatgcag aacagctttt
    37261 ttacaacctc tccaataaac gatgttcaat cagctgtccc tcgatattag ctcaaaaaac
    37321 ggcaaaatat gaggaactat ttttccgttt gtttctctaa tactcaggtc aaaccgctga
    37381 tttcacaacc tctgattcac ggtgttccag aagcagcttc tacggaaata agctgaacac
    37441 ttttgttaca acttcttttt ttctggagtt tcttggcgca tatttttgga gtccttctga
    37501 ataaagcgta aaataaaagt gagaaatatg gataaaggag ggaaaggaga tgctgaattt
    37561 tttatggtcg ttatttatcg gcggtatatt aggtttgata gctggcgcaa ttttaggaaa
    37621 ggaagtcccg ggaggcgtat ctggaaatat cattatcggt tttttaggta gttggctcgg
    37681 cgaattttta ctaggaccac tgggaccgga actcggcggt ttttatttga taccagcatt
    37741 attgggtgca attttttgcc ttgctcttta ttcatttgtg gcaagacgta tcagagaacg
    37801 tccaaagaaa gaataatttt attcaaataa gttgacactt cagtgtgtta cttggataat
    37861 tagaagcaat ttaggaaagc gggtgtcatg gataagaata tcatctatca ttcaagctta
    37921 cctaaaggat atccatataa caagaaatga gggaaaaacg tggcaacaac gcacaatacc
    37981 aaaaagatat caatgactgg cctgcttgta gcgatgggag tcgtctacgg agacatcggg
    38041 acaagtccgc tttacgttat gaaatcgatt gttgaagata atggcggatt gtcaggaatc
    38101 aatcctgatt ttgttatcgg atcagtctca ttgatttttt ggacattgac tctactgaca
    38161 acaatcaaat atgtcgtgat tgcattgaat gcagataacc atggtgaagg tggaattttc
    38221 tcactctaca cacttgtccg aaaaggtggg aaatatttga tcattcctgc aatgatcgga
    38281 ggagctgcct tactagcaga tggggtattg acccctgctg tgacggtaac gactgcgatt
    38341 gaaggcttgc gaggaattcc gcagtttttt gaccggttcg gtaataacca gaacgtgatc
    38401 gtcattatca ctttagttat tatttttgtt ttattcatgg tccaacgctt tggtacagat
    38461 attgtcggaa aagcattcgg accaatcatg ttcgcttggt ttactttttt aggcgtaatg
    38521 ggattaatga acttcagtca agactggaca gttatccgtg cactgaatcc ttattatgct
    38581 atccagctgc tttttagtgc agataacaaa ttaggcttgt tcattcttgg aaatattttc
    38641 ctggctacga caggtgcaga ggcgctttat tccgatcttg gacatgtcgg caaacgaaat
    38701 attcgtctga gctggcctta cgtcaaaatt tgtttggtta tcaattattt tgggcaggct
    38761 gcgtggttgt tgaatgttta tcaaaaccct gaagcacagc aaatcaagaa cctgaatcca
    38821 ttcttccaaa tgatgcctca aagttggatc gtgatcggcg ttgcttttgc aacagtcgct
    38881 gcagtcattg cttcgcaagc attgattaca ggttcgttta cgctagtttc agaagcaatc
    38941 aagttgaaac tgctgcctcg gttaaagatc atgtatcctg ggaacagtat cgggcaaatg
    39001 tatatcccag cagtcaatct gattttatgg atcgcctgtt ctctagtggt tgtcacattc
    39061 cgaacgtctc atcatatgga agctgcttac ggtctatcga tcactgtgac gatgttgatg
    39121 acaacagcac tgctttactt ttatcttatc caaaatgggc attctcgttg gcttgcatat
    39181 ttagttacct ttttcttcgg tgcgatagaa gtcgttttct ttatctcaag tgttgtcaaa
    39241 ttcttccgag gcggttttgt agccgttctg attggtttga tcatcttagt cgtgatgttt
    39301 atttgggaac aagggaacat tattcgcgaa tcgtcaaccg aggatgtgtc tttgagagat
    39361 tatatcccgc agcttagaga attacgtgat gatacttctt taccaatcta tcagacaaat
    39421 gtggtcttct tggttcctga tatggctgaa gataaagttg gccgacagtt catctattcg
    39481 attttagata aacggcctaa aagagcacga gtctattggt ttgttcatgt ggaagtgacg
    39541 gatgagccat atacgaaaga atatcaagta gatatgatgg acactgattt tattgtccaa
    39601 gtgaatctgt tcttaggttt cagggtccaa caggaaatca acgtatatgt tcgccaagtc
    39661 atccatgatt tgatgaaaca aggccgtttg ccaaaacagc cacaaagata ctctctgaca
    39721 ccagggcgag aagttggcga tttccaattt gtcctgattg atgaagtagt ttccaatgtg
    39781 acaactctag gaaaatggca acgtcaaatc atgcaggcaa aactggcaat caaaaaaatc
    39841 gctacctcgc cagaaacatg gtttgggcta gagtacagcg aagtaaaaca tgaaactgtt
    39901 ccgcttatca ttggaaatac tcggaaaaca tggttgaaag agcggttgtg aaagtagcgc
    39961 tttgacctga actaatgtcg aatgtcagct acttgaacac cgtttatcag aggtcatgaa
    40021 aaagctgtac tgcaacaagc agtaagaacg agcagataaa aacagcttct catgtttttc
    40081 atctgtttgg gcttaatgcc gtagatgcaa gcttttgaat accgttttta tcagaggtca
    40141 tgaaaaagct gtttagcaac aagtaacgca atgattttga agtgataagg agatgtggct
    40201 gaaaaatgcc gcatctcctt ttttattcct aaatatgaat acgcattatt ttcaatcttt
    40261 ttgtagaaaa agggtacaat agaaaaagag aaaggcggga gaatatggtt atcaatttca
    40321 ttattttatt tttgatgatt gcaattactt cattttttgt agcaagtgaa tttgctttag
    40381 tgaaaatcag acgatcaaga ttggaacaac tagaaaagga aaatgtaaag aacgccaagc
    40441 tagctcttca tgttacacac catttagata actatttatc agctagtcaa ttaggaatta
    40501 cgctaaccgg tttgatcatc gggtgggtcg gtgaaggatc tgtcgcggct ttactagaac
    40561 cagtgatcgg taaactacct tttagttcgg ctattagcag tacaatctct gtggcgctgg
    40621 gatttatttt agttacgtat atcgatgtgg ttattggcga actgcttcct aagagctata
    40681 gtatcgtcaa tacggagaag gtcgtcttgt tcgtagttaa accacttcat tatttttata
    40741 aagtaatgtt tccttttatt tgggtattga atcattcagc tgcagggcta gggaagctat
    40801 taggtgtgcg tctcgtatct gaaggagaag agacattgtc tcaagaagag ctgacattag
    40861 tcgcattgaa ttcttatgaa aaaggagagt tgaccaaaga agaatattat tatttggaaa
    40921 acgtgtttga atttgatgat accttggcaa aagatataca agtagaccgt acgtccatgc
    40981 aagtattcga agcttcagaa accgtcaaag aagcgataaa agcttcgatt gaacaaggac
    41041 atactcgcta tccggttatc ttagaatcaa aagacaatgt tttaggttat gtcaccttgc
    41101 cagatttgat caagcaatct tataaagatg accagctgac agtagaacag ttgattgaag
    41161 agccgatcgt aacaactgaa acgatcccta taaaaaaatt attgacgatc atgcgaaaaa
    41221 agggtaagca tattgctatc ttaaaagatg aatacggagg gacaagcggc ttagtgacga
    41281 ttgaagatat tttagaagaa atcgtcgggg aaatccgaga tgagacagat ttggacgaag
    41341 cattgatagc ggaacagtca gatggctctt atatcatctc cggcaaacta acattagatg
    41401 atttccagcg ttattttcat gtagagattc cagagtttga agaaacgaat tttactacac
    41461 ttgcgggctt tgcttctagc cgatataaag aaataaaagc aggaacaatc attgagattg
    41521 catcattccg tttcacggta ttagaatacc agcatgcaca tatcgattat ttcaaagtag
    41581 agtccacgga aagaaaaaca gaataaaaga aaaaaggctg tgacattttt tgtcacagcc
    41641 tttttgttat ctaaaaaacc tgttttcggt aaacgaagaa gatattttca ataaaagttt
    41701 tcatttttag ccgcaacgat ttcttttaat caaggctatc ttgcttctgc atgttctaat
    41761 gtgaaatgtt cctcttcacc catgtgtttc aattgtttca tcgaacgcat ataagagtaa
    41821 agcaacacgg caacagaacc gatccaagct aaaggagaag ctgctgctgc tcctgggtat
    41881 ccccacattc ctgtaagaac gatagctgca aaagaacgca taagcaattc catcataccg
    41941 gcgatcgtag ggatcttgct ttgtccaagc ccttgaagtg tgtagcgtaa aatgaacagg
    42001 actgctaaga tccagtaaag agacccattg atattgaagt aggtttgtgc taattcaaat
    42061 acacgtgttt ctgatgggct aacaaacaat tgaacaaaga aatgaccgaa gaaaatgacg
    42121 atagcacctg ctaagagact aaatccgaca ctcatcagta aagtttgacg taccccttgc
    42181 aagattcggc catattcttt cgcaccatag ttttgtgcag tgaaagttgc cattgcaata
    42241 ccaaatgaca tcatcggctg atttgcaaat tggtcgatac gaccagcagc ggcttgagca
    42301 gctacgacat ctgtccctag actatttagt gctgcttgta acacgatagc accaacagcg
    42361 atgatcgaag attgaaacgc cattggcaaa gcagcattta ggtgtacagc aaactcttct
    42421 ttttcaaatt tgaaatcttt tttgcgtaac tgtaacaaag gcattttttt cttgatatac
    42481 actagacaca gtacgctgga agaaacttgt gcgattactg tagcaatagc tgcaccttcc
    42541 acacccatgc caaaatagat aataaagatc aaatcaagta cgacgttgat gatgaccgca
    42601 atgatcagaa agaatagtgg tgtgcggctg tcaccaagtg cgcgaatgac attagaaagc
    42661 aaattgaaac tgactgatgc aaagatccct aataaaataa ttgaaataaa tgtttgtgct
    42721 tgatcaagta tttcaggagg agtttgcatc aattgaagca tcggacgaat aaacaggaga
    42781 cttaggacag ttaaaatcac agtgacgaca agactaatga caacactagc agcaaaactt
    42841 ttcttcagac cccgataatc ttttgcaccg taacgttgtg cggtaataat ggctaaacca
    42901 gctgttaaac cttgggcaaa gccaatgatc aaaaatgtca ggcttccagt tgcaccaacc
    42961 gctgccagcg catttttacc tagcgtctga cccacgatga tcatatcgat catattgtag
    43021 aactgctgaa aaacatttcc gatcagtaaa ggaacagtga acatcaaaat cagtttagcg
    43081 gggcttcctt ttgttaaatc gcgcatcttt taaactcctt atatctttaa aatttagtta
    43141 gtagtatata gcgtttatcc tgagaatacc aattagaaat caatgataat ttatgaaact
    43201 ccataaaaag aagccaagaa ttgagtcaaa gaatcaacaa cttggcctgg tctgtaaaat
//
LOCUS       DADQCX010000013        42070 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.013, whole genome shotgun sequence.
ACCESSION   DADQCX010000013 DADQCX010000000
VERSION     DADQCX010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.013"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..2849)
                     /gene="ileS"
                     /locus_tag="J8R83_000656"
     CDS             complement(51..2849)
                     /gene="ileS"
                     /locus_tag="J8R83_000656"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAZ9573811.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(3111..3818)
                     /locus_tag="J8R83_000657"
     CDS             complement(3111..3818)
                     /locus_tag="J8R83_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAZ9573812.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            complement(3839..4621)
                     /locus_tag="J8R83_000658"
     CDS             complement(3839..4621)
                     /locus_tag="J8R83_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAZ9573813.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            complement(4670..4957)
                     /locus_tag="J8R83_000659"
     CDS             complement(4670..4957)
                     /locus_tag="J8R83_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAZ9573814.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            complement(4972..5571)
                     /locus_tag="J8R83_000660"
     CDS             complement(4972..5571)
                     /locus_tag="J8R83_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAZ9573815.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            complement(5585..6262)
                     /locus_tag="J8R83_000661"
     CDS             complement(5585..6262)
                     /locus_tag="J8R83_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAZ9573816.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            complement(6279..7520)
                     /gene="ftsZ"
                     /locus_tag="J8R83_000662"
     CDS             complement(6279..7520)
                     /gene="ftsZ"
                     /locus_tag="J8R83_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAZ9573817.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            complement(7543..8868)
                     /gene="ftsA"
                     /locus_tag="J8R83_000663"
     CDS             complement(7543..8868)
                     /gene="ftsA"
                     /locus_tag="J8R83_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAZ9573818.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            complement(9024..10244)
                     /locus_tag="J8R83_000664"
     CDS             complement(9024..10244)
                     /locus_tag="J8R83_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAZ9573819.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            complement(10259..11347)
                     /gene="murG"
                     /locus_tag="J8R83_000665"
     CDS             complement(10259..11347)
                     /gene="murG"
                     /locus_tag="J8R83_000665"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAZ9573820.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            complement(11373..12734)
                     /locus_tag="J8R83_000666"
     CDS             complement(11373..12734)
                     /locus_tag="J8R83_000666"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAZ9573821.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            complement(12748..13710)
                     /locus_tag="J8R83_000667"
     CDS             complement(12748..13710)
                     /locus_tag="J8R83_000667"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAZ9573822.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            complement(13736..15928)
                     /locus_tag="J8R83_000668"
     CDS             complement(13736..15928)
                     /locus_tag="J8R83_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAZ9573823.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGMFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            complement(15929..16330)
                     /gene="ftsL"
                     /locus_tag="J8R83_000669"
     CDS             complement(15929..16330)
                     /gene="ftsL"
                     /locus_tag="J8R83_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAZ9573824.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            complement(16335..17294)
                     /gene="rsmH"
                     /locus_tag="J8R83_000670"
     CDS             complement(16335..17294)
                     /gene="rsmH"
                     /locus_tag="J8R83_000670"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAZ9573825.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            complement(17315..17746)
                     /gene="mraZ"
                     /locus_tag="J8R83_000671"
     CDS             complement(17315..17746)
                     /gene="mraZ"
                     /locus_tag="J8R83_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAZ9573826.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            complement(17916..18284)
                     /locus_tag="J8R83_000672"
     CDS             complement(17916..18284)
                     /locus_tag="J8R83_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAZ9573827.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18455..19411
                     /locus_tag="J8R83_000673"
     CDS             18455..19411
                     /locus_tag="J8R83_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAZ9573828.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            19484..19600
                     /locus_tag="J8R83_000674"
     CDS             19484..19600
                     /locus_tag="J8R83_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAZ9573829.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(19655..21337)
                     /gene="recN"
                     /locus_tag="J8R83_000675"
     CDS             complement(19655..21337)
                     /gene="recN"
                     /locus_tag="J8R83_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAZ9573830.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(21355..21804)
                     /locus_tag="J8R83_000676"
     CDS             complement(21355..21804)
                     /locus_tag="J8R83_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAZ9573831.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(21911..22729)
                     /locus_tag="J8R83_000677"
     CDS             complement(21911..22729)
                     /locus_tag="J8R83_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAZ9573832.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(22738..23628)
                     /locus_tag="J8R83_000678"
     CDS             complement(22738..23628)
                     /locus_tag="J8R83_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAZ9573833.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLTRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(23630..23854)
                     /locus_tag="J8R83_000679"
     CDS             complement(23630..23854)
                     /locus_tag="J8R83_000679"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAZ9573834.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(23859..25196)
                     /locus_tag="J8R83_000680"
     CDS             complement(23859..25196)
                     /locus_tag="J8R83_000680"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAZ9573835.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(25197..26051)
                     /locus_tag="J8R83_000681"
     CDS             complement(25197..26051)
                     /locus_tag="J8R83_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAZ9573836.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(26148..26597)
                     /gene="nusB"
                     /locus_tag="J8R83_000682"
     CDS             complement(26148..26597)
                     /gene="nusB"
                     /locus_tag="J8R83_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAZ9573837.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(26590..27015)
                     /locus_tag="J8R83_000683"
     CDS             complement(26590..27015)
                     /locus_tag="J8R83_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9573838.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(27261..28325)
                     /locus_tag="J8R83_000684"
     CDS             complement(27261..28325)
                     /locus_tag="J8R83_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAZ9573839.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(28497..28742)
                     /locus_tag="J8R83_000685"
     CDS             complement(28497..28742)
                     /locus_tag="J8R83_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9573840.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(28881..29255)
                     /locus_tag="J8R83_000686"
     CDS             complement(28881..29255)
                     /locus_tag="J8R83_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAZ9573841.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(29338..30252)
                     /locus_tag="J8R83_000687"
     CDS             complement(29338..30252)
                     /locus_tag="J8R83_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAZ9573842.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(30273..31076)
                     /locus_tag="J8R83_000688"
     CDS             complement(30273..31076)
                     /locus_tag="J8R83_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAZ9573843.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(31109..32098)
                     /gene="manX"
                     /locus_tag="J8R83_000689"
     CDS             complement(31109..32098)
                     /gene="manX"
                     /locus_tag="J8R83_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAZ9573844.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(32201..32692)
                     /locus_tag="J8R83_000690"
     CDS             complement(32201..32692)
                     /locus_tag="J8R83_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAZ9573845.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(32883..35717)
                     /locus_tag="J8R83_000691"
     CDS             complement(32883..35717)
                     /locus_tag="J8R83_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9573846.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            complement(36124..36417)
                     /gene="rpmA"
                     /locus_tag="J8R83_000692"
     CDS             complement(36124..36417)
                     /gene="rpmA"
                     /locus_tag="J8R83_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAZ9573847.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(36430..36774)
                     /locus_tag="J8R83_000693"
     CDS             complement(36430..36774)
                     /locus_tag="J8R83_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAZ9573848.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(36801..37109)
                     /gene="rplU"
                     /locus_tag="J8R83_000694"
     CDS             complement(36801..37109)
                     /gene="rplU"
                     /locus_tag="J8R83_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAZ9573849.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            37391..38032
                     /locus_tag="J8R83_000695"
     CDS             37391..38032
                     /locus_tag="J8R83_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAZ9573850.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(38094..39725)
                     /locus_tag="J8R83_000696"
     CDS             complement(38094..39725)
                     /locus_tag="J8R83_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAZ9573851.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(39848..40207)
                     /locus_tag="J8R83_000697"
     CDS             complement(39848..40207)
                     /locus_tag="J8R83_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAZ9573852.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            complement(40366..40439)
                     /locus_tag="J8R83_000698"
     tRNA            complement(40366..40439)
                     /locus_tag="J8R83_000698"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40403..40405),aa:Arg,seq:tct)
     gene            complement(40748..41431)
                     /locus_tag="J8R83_000699"
     CDS             complement(40748..41431)
                     /locus_tag="J8R83_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAZ9573853.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            complement(41559..>42070)
                     /locus_tag="J8R83_000700"
     CDS             complement(41559..>42070)
                     /locus_tag="J8R83_000700"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9573854.1"
                     /translation="YKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEMSPY
                     YAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTKTYI
                     EPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVELKK
                     KRRRTQKFL"
BASE COUNT        11801 a         9200 c         7037 g        14032 t
ORIGIN      
        1 gataacaaaa gggggtgtga caaagaacat gtcacacccc cttttccctt ttacttttct
       61 tcgaatcctt cagctacagc ttcaggatag aagtcttcaa cgatttttgc acaacgaccg
      121 catagatgag gaagtttttc atctactcct acatctttac gaacttggcg acagcgatcg
      181 caagtttccc cgtctgcttt ttccactgta atagcaacat catcaaatac catagcgtta
      241 tctggcactt gttcatctgc tgccataact tcaaagtagt ctggtgaaac gatcaataat
      301 tgtgcaatat ctgcatccaa agcttttaac atttcacgaa cttgttgttt tggataaaca
      361 gttagttttg cttccaaaga tttaccaatc aatttgctgt ttcttgcttc ttccaatgct
      421 tttaagacat tatcacggaa gtccatgaaa gcagtccagg tatccatcaa ttcttcttgg
      481 tttgcaaact cttcataacc aggaaactcg cttaactgaa cgtactcctc ttcttctttc
      541 aggaatgacc agatttcttc tgctgtatgc ggaatgatag gagtcaataa ttttgtcaaa
      601 gctacagctg tttgatagaa aacagtttgc atgcaacgac gttgataatc atcttctgct
      661 tcaatataaa ctacatcttt agcaaaatcc aggtagaatg acgatagatc aaccgtcaag
      721 aagttcataa ctgtacggta aatatgcatg aagttatatt tgtcgtaccc ttcttctcgg
      781 atttctttga ttacttggtt caatcgaacg gtcatatatt tgtctacaga acgtaaatca
      841 ttgtacgaaa cagtatcttt tttaggatcg aaatcttctg tattcgctaa taagaaacgc
      901 atcgtatttc tgattttacg atatacttct gccacttgac ttaagatatc catagaaaca
      961 cgaacatctg cttcataatc tacactagat acccataagc gaaggatatc tgcaccaaat
     1021 tgtttgatca ctttttctgg tgcaatgatg tttcctaaag atttactcat cttacggcct
     1081 tcaccatcta aagcaaatcc ttgagaaata actgatttgt atggtgctac accattgata
     1141 gccacactag tcgtgatact tgagttgaac cagccacgat attggtctga tccttctaaa
     1201 tacatatctg ctgggaatga taattctggt cgctgacgta aaacagcttc atgagaagaa
     1261 ccagaatcaa accagacatc catgatatct ttttcttttg taaattcgcc attaggagaa
     1321 cctgggtggg taaatccttc aggaagaagt tctttcgctt ctttttcaaa ccagataatt
     1381 gatccatgtt cagcaaataa ttttgccaca tgttcgattg tttctggtgt gatgattgct
     1441 tctccatttt cagcatagaa aatcggaagt ggtactcccc atgcacgctg acgggaaatt
     1501 acccaatcgc cgcggtcacg gatcatatta tacaaacgtg ttttacccca tgggataacc
     1561 cactctactt tttctacttc atccaaaata ttctgacgga atttatcgat agatgcaaac
     1621 cattgtggag ttgcccgata gatcacaggc tttttcgtcc gccaatcgtg aggataacta
     1681 tgagtaaaga aatctagctt cagcaaagct cctttttctt ttaatagatc agtgatcata
     1741 ggatttgctt tgtcataaaa gataccttca aatccaggtg cttcttctgt aaacaatcct
     1801 tttgagtcta caggtgacac tacagatagt ttatatttgc taccagcgat atagtcatct
     1861 tccccatgtc ctggagcagt atggactaat ccagtaccag cgtctaaagt aacatgatcg
     1921 cctaaaatca caagtgattc acgttcatag aatggatgac ttgcagtcat atattccatt
     1981 tcttgtccag caaattcttt tagaactgtt acattttccc aaccgatttc tgattggact
     2041 gtttctagca aatctttcgc tacgacaaac ttacggccat cggcttccac caatacatac
     2101 gtaaattttg gatttacagc aataccttgg tttgctggca atgtccatgg tgttgtcgtc
     2161 caaatgacaa aagctgtatc ttcatcaaga atatctttgc cgtctttgac attgaaagct
     2221 acaaaaatag atggagattt tacatcttta tattcaattt cagcttccgc taaagaagac
     2281 tcacttgacg gagaccagta aattggtttc aatcctttgt aaatatagct tttttcagcc
     2341 attttaccaa atacgcgtac ttgtgcagct tcataagaag gatctaatgt aacataagga
     2401 tgttcccaat ctcctgcaac tcctaggcgt ttgaaatctg ctcgttgctt atctacttgg
     2461 gaaagtgcat attcacgaca tttttccaag tattctgcca tggacatttc tttacgtttc
     2521 acgcctttat tagccaatac ttgttcaatc ggcaatccat gtgtatccca tcctggaaca
     2581 tatggtgcac gatagccaga cattgatttt gaacgaatga taatgtcttt actgatttta
     2641 ttcaatgaat gtcctaaatg gatattacca ttggcatatg gaggtccatc atgaagaaca
     2701 aagctaggtt ttccttcgtt caactcttgt cttttttggt agattcgatt ttcttcccat
     2761 tctttttgcc actcgccttc tcggtttggc aaattaccac gcatagggaa ttttgttttt
     2821 cctaattgca aggtttcttt cattttcatt caaccataca ctcctttatt tgttttccgg
     2881 acacaaaaaa gcatgttcag ccgcaaggga cgaacatgcc gtggtaccac ccaaatttag
     2941 ttgcatctat ctagtgcaaa ctctctgtga ccaataacga ggtcagccgc tgcttcttac
     3001 tctaatttcg gaaaagcagg tctcaagtag aggatctttc accatgcagt gtcttaccga
     3061 acttccactc tcatcggctc gctttaagaa taacaaagtg cttttctgtt ctactcgttt
     3121 tcattttcac caggcacgat cgagatatca atagcctgtg tatcaaatgc cgtcataggt
     3181 gcttctatga ctcctgtgtc tgagtttaca tcagtatcat tttcattgtc aagctgtttt
     3241 gctaaaactt ctttgatcac ttcatggctg tcagtcacgt agctggagaa tggttgtaaa
     3301 atttcatccc attccggact tttcacttgt tctaattgag actcaagcat caagctgata
     3361 cgttgatgga atactcgtgt ttttttctta agatcttcag tttctgtcgc aagctgtctt
     3421 gctttttctg ttgcatctgt caagattttt cttgcttttt cttctgcatc agttgttaat
     3481 tgatgtgcac gtttttcagc gttcgcaact aactcatctg ctttgttttg tgcagaagta
     3541 acgatcactt cggattcctt gcttgcactt gtttttactt tatcagccgt atcttgagct
     3601 acgatgattg attggttcaa agcatctttt aattcattga agtactcaag tttttcttca
     3661 gaatgtttga ctgctttttc taattctcga tttctttgag tcaattcctc atagtcacga
     3721 acaactaaat ctaagaaatc atctacttcg tcttgattat atccccgcat ttttgtcggg
     3781 aatgtcttat tttggatatc taatggagtt aaagccatga gtaaaccacc tttttatttt
     3841 atttacgtaa tacaccgaac agtaccctgt acttttcttt tttcgtcttc ccctcaagtt
     3901 cttggatctg gactctgcca taacctctga ctgaaataat atctaatagt tcaagtacaa
     3961 aatcaggtct tgtattttct gtccagttca cttttacttt accagcttcg atcagctgct
     4021 tggaccgctg tctggaaata ttataaatct cagagatcac actgtctagt cgcatggaac
     4081 taactgttcc tctttcttgt gtccagctat ctttcggcat aatcatttct gtgtatttga
     4141 ttggttccaa gcgtacagca acctttccaa tctttgttac ttgtgcagca acaaaatgat
     4201 ccacctcatt tgcaataaat acttgccagc gatcaccgtc cgagatgata tcgccaaagt
     4261 aagagcgttt gatccccgtt cccactaaag ttccaaggat tttcccatga cttaggctgg
     4321 caaatttgct aggataatgg atttcataca atgctgtttc aaaatcttcc tctacaggtt
     4381 cgtaataatc ggggaaaatc aaacatcttt ttctttctgc ctgttcatat ccgccataaa
     4441 acatgaaacg caaatcactg ctttgtcgaa tcagtgtttc taaaatatag gattgtcttg
     4501 ggtcaagaaa ttcggtcaga tagggtgcat attgtccttg aacctgttca atccaatcgc
     4561 ctaccgaatc gataaatgta cgttcatctg cccgaaagtg ctggtataca tttgcatcca
     4621 aaattttccc ctcctatcta ttctgagaat aaagattttg ttgcttcaat caataaacta
     4681 aatggacagt tatccatata acgatctgtg ctaaaccttg tacggctaag ttcaagatca
     4741 ggattgcccc taaaattgtg aaatccaagg gtccaatcct caaaggcaga cgatcgaaca
     4801 aactgatata cggttcgcag atcttagcta ataatcgtcc tagccctgat tgatacccgc
     4861 ctggaaacca agagagcaat gcatatacca tcaagataat gctatagaaa taggctgccc
     4921 gttgaagtaa atgaagtaat agtgcaatag tataaatcgt agttcctcct cttacagatc
     4981 aaacaaattc gcatctgcaa aagattgagc ggttgaactg tcaatctcca tcccagtcgg
     5041 tgtacaaaga aaaatctcat ctccaacacg tttgatatct ccatctagtg cataaactgt
     5101 tcctgttaga aaatcaacga ttcttctcgc ttgtttttct tctactaaat gaaaattcac
     5161 taaggttgct tctccagcaa tgattcgttt agcaatcgcc atagcttcag aataagctct
     5221 tggttccatt acagtgattt ttccagcaag atttgcttta ggttgtgtag aggttcttga
     5281 agctgttctt tctttcgcta cagtttttgt aggtgattga tgtagttcaa ttactttttt
     5341 cttttcagcc ggctgaatac tttcatgcgt tacaggacgt gaagtcgccg ttttttgttt
     5401 ttcatgagta ttcgcagcag atacagaatg agttgattga ttctgtgttg tatttttttt
     5461 agttggctgt acagcctttt ttgttgtttc aggataatct tggtattcgt actcttcctc
     5521 atcagctaat ccgaaaaaat tagcaattgc tcctctgttt aaaagcggca tttttgttcc
     5581 tcctttattc gtctttgaat agcgctgttc ctacacggat aaatgttgca ccttcttcaa
     5641 tcgcaatttg aaagtcttga ctcatcccca tacttaattc actacatggt gcatgggcat
     5701 aaccttttgc ttgaacaaga tcacgcaatt ctttcagcgt accaaacact ttatggattt
     5761 gctcatcaga agcttcttta ggcgccatag tcatcaaccc aacaaccttg atttttgtgc
     5821 aggcagctaa agattccaca aacggtaaaa gctcatctgg tgaaattcca tgttttgatt
     5881 cctcaccaga aacatttact tcaataaaac aggataattc tttctctaac cgcttctgga
     5941 tttcttctgc taatcttaaa ctgtccaacg catgaaagta atcaatttca tttacaatca
     6001 attttacctt tctgcgctgt aaattaccaa ttaaatgcca ctttatttca ggaaaatcaa
     6061 ataaatcttg tttcttttct aataatttat ctactcggtt ttctgcacaa ttcataacgc
     6121 cagctctaac caattcttca gcttgagcgg attcaacaga ttttgttaca gctactaatg
     6181 taacttcttt cggatcacga tgaacaagag cacacgaatc ctgaatttct tgcttgattt
     6241 tctgcaagtt gtcagcaatc atgtgctctt cctctccttt attttttacg acggaaaaac
     6301 ggtggcgtat ttaattcatc atcgccatga gattttgttt cttcgcggtt gaatgtatca
     6361 aattcttttt tttcgatatt gtcaaaattg gaatcatcaa ctctaggacg aacattttgt
     6421 tcacgtctga tatcccaatc gccaaaactg ttttcttctt ctgaagaagt tggtttagct
     6481 tgatccatat ctaatacagt cttttgagca ggtgattgca tttgtgcttg tctagctggt
     6541 cggctagact tgcgttcctt ttttgattca tcgatacctg ttgcgatgac cgtcacacgg
     6601 atttcatcgc ccatttcttc attgatagat gtacctagaa tgatatttac atcgccagtt
     6661 gctgcatttg ctacgatatc tgaagcatct tgtgcttcga acaatgtcat atccaaaccg
     6721 cctgtgatgt taagaagtac ttgttcagct ccatcaatag atgtttcaag caatggagag
     6781 gagattgctt ttttcgttgc ttctactacg cgatcttctc cactagccac accgatcccc
     6841 atcaatgctg taccttggtt ttccatcact gttttcacgt cagcaaagtc aaggttaacg
     6901 taacctggcg ctgtgatcaa atcagagata ccttgtacac cttgtcgtaa aacattatct
     6961 gcttcacgga aagcttcaag catcggtgtc tttttatcta caacttctaa taaacggtta
     7021 tttgagataa ttaataatgt atccacattt tctttcaaac gagcgatacc ttctgcagca
     7081 aaacggccac gtttcggtcc ttcaaaagtg aatggacgtg tcacgacacc aacagtcaat
     7141 gcgcccaatt ctttcgcgat acctgcaacg attggtgcag cacctgtacc ggttcctcca
     7201 cccattcctg cagtgatgaa aatcatatct gcaccgtcta aagcttcgcg taaggattgt
     7261 tcactttctt ctgccgcttt ttgtccaact tctggctgag aaccagcacc taaaccacga
     7321 gtatatttgg ggcctaattg gataactgtt tcagcttttg aattttttaa tgcttgcacg
     7381 tctgtgttgg ctgtaatgaa ttcaacacct ttaacgtttt cttcaatcat tcggtttaca
     7441 gcatttccac cgccaccacc gactccgatg actttgatta ctgcgccgtc attgatatta
     7501 ttatcaattg agaattccat atcttattcc tcccaggatg aattaatcaa aaatatttgt
     7561 aaagaaaccc ttgattttat tttttacatt ttctccggac tcttttggtt ccggctcatc
     7621 gtagattgtt tcttcaggtg cttcatagct ctcatatgtg tttgttgttt cttgttcaac
     7681 taccatttga cgagctgctg aggtttcacc cgtaacagca atttttgcca attgatacac
     7741 ttcactcaag tttgctgaat aatccacgat acttattaca tttgtaaata ccgggtttct
     7801 cagccccatg tgatttggaa catacaattt tacatttacg ccgaagattt cttgtgccaa
     7861 gtccacaaca ccaggaagac tagcagctcc gcctgtcaat acgacgccac ctggcaactc
     7921 taatgcttcg atttggtcca atgcatcttt tgctttgttg aaaatctgtt ccattcgagc
     7981 tgaaataatt tctgacaagt agcgttcatc gactttcact ggttctgact gaccaatcac
     8041 atctactgga aattcttcat ctggtgatgt ccgttctggg tatgcatccc cgtagtttat
     8101 tttcaacgct tctgcattgt taaatgacgt atttaataca atagagatat ctttagtgac
     8161 aaattcgcca ccttcttggt caagattggt aaacttcaat tgcttatcat gcataacagc
     8221 cgttgttgtt tggccgccac ccatatcaat gacgatcgta ccaaaatctt tttctccgtc
     8281 agaaagaatt gattcagtca gcgctaaagg agtaatcacc atttcgttga cgattaatcc
     8341 ggcattttcc acgcatttac gtatgttatg gatgatcgtt ttaggtcctg taaacaacag
     8401 accgtacatt tctaatctta cgccgatcat tccacgagga tctttgattc cctcgaaccc
     8461 atcgacagta aaatcttgtg gcaatattga cacgatttga cgttcaggag gtattgaacg
     8521 aacaagggca gctgaagcca catttctgac atcttcatcg gtgatttcct ttgaatctcc
     8581 gttaactgca atcattccct ggcaattttc tacttcaagc atgtttgctg gcaaaccgac
     8641 acttacgcct ttgatctgga tacctgcttt ttcttctgct tgtcgtactg ctcgttgtat
     8701 cgcttggacc gttttatcga tatcaacgat aatgcctcgg ttaatccctt ctgattttgc
     8761 gtttcctact ccaataatat tcatttggct gtcgatatat tcagccacga caactttaac
     8821 agatgtcgtt ccaatatcaa ggcctacata cattcctgtt tttgccatga atgggattcc
     8881 ctcctactta ctattccata tacaagcgaa caactagcgt ccgttttaaa atatacttat
     8941 taatagatat attcactgct tccaattcta ccataaatta ctggttttta gaaagtacat
     9001 tcttactttt taaagttgtt ttatcaattt tcatttaaac ttgacggagt tgtacttgga
     9061 ttatcttcta tttgacttgt ttcacttgaa tcatttgaat cagatgatcc gtttgtgcta
     9121 gacgatccag gtgtttgtgc tttttgcgtt tctgcctctt cacttgattc gtttgtttga
     9181 tccgcatttt cttcactttc agttgtttct tccgattggc ccgattcttc cgtttcttga
     9241 gtgctaccgt aaggatgcga gaagatacca acttccatgt cgatcacacc tttttcatcc
     9301 atatctttgg ctacttgcga ataatatttc atttggttcg caagattatt gatatttaca
     9361 ataacttgat tgccgtcatt catattcaat tggatcagat ttttattgct tgctcttggc
     9421 gtgtacttga tttcagaaat tgctttttgt aattctgatg ataactgatt gtattgcttt
     9481 gttaattctt tgatttttgc agagtctttg aactcttcca agatagggag attttttgta
     9541 ggatttgcta ctttttcatc taatactgtt ccattttcaa tcactgggta gtattgattg
     9601 ttttttgcga tcaaagcaat ctctttatat tctgttacat ccaaatcgaa ttcattcatc
     9661 cctttgaaat gtatatttgc tgtttcgatt cttggctgtg cttttttaag gcgatcgata
     9721 taagtagatc gatgaaaata ctgtccccaa acattttctc ctaatgacaa ttttgtatca
     9781 gagatgattt cttggctgtt gactgtctta ttgcctgata ctgcaactgc ttgtaatttg
     9841 ctataaggag aaacataata gatcaaaaaa atcagcggta tacccaatac agtgatgatc
     9901 aaagctaacc gacgaaatag tactttgtgc cgttgacttt ttaaattggg cagccggttc
     9961 aaaaaagaac cgttatatgg tccaccgttt ttcttttgct tgatctcttc aaaaaattcg
    10021 atttttttct cggactggct ttcttcttgc tgttcctctt gaaccgtttt ttcttcttca
    10081 gaatctgaaa ggggtgtatc taatgttatg tcttcttttt ttggctcttg gtttttcatc
    10141 tcttgttctg ccagatattt tcggttagcc ttttgccaag gagtcaaatt gttttcatca
    10201 gaagacggat gagacaattt ttttggttct tttttcttac tcactaagac caccgccttt
    10261 attttttgat tatttgtttt actaagtcat aaagacgttt tgaagcatca gggattcctt
    10321 gttctttaga agctcggcac atttgctttt gcaattcttc atcacccatg atttcgttga
    10381 ctgtctgact tagtgattca cctgttagtt cattatctgc aatcattttt gctgctcctg
    10441 cgtgaacaag actcattgca tttttagtct gatgatcatt cgtaacatat gggctgggaa
    10501 ccaacactgc cggtaacccc agagctgtga attctgcgat cgaagttgca ccagcacgcc
    10561 ccaccagcag atcactggaa gccatgacct ctgccatatt tttgatataa ggctggacac
    10621 taatattttg tatttcagga tttattttat ttaggatctc ttcataatat ctatctcctg
    10681 aagcatacaa aacttggtaa gaagaaggaa tatattcact taaaaaaact gatactgctt
    10741 gattgatttt aagtgctcct tgactaccgc caaaaatcaa gactgttttc ttttctggat
    10801 ccaaatcaaa tgttttcaaa atatctgatt ttttagtatc tgctacttct tgtgctcgag
    10861 gattacctac aagaactgct ttgttttcag gaaaaaagga agccgcatct ttaaatgaaa
    10921 gagcgatccg atccacatat cggcttaaaa atttattggt aacacctggt acactgtttt
    10981 gttcatggat aactgttgga atacccattt tggctgcagc gtacactacc gctccggaaa
    11041 catatcctcc agtaccgata acgatatctg gttgaaaatc actgaggatt ttttttgctt
    11101 gacggatact cttaagaaac aatcggaccg tcttgatgtt atgcatggaa atttttcgtt
    11161 taaatccttg aatctccaag gtatggaaag gcattcctgt atcagggacg attttgtttt
    11221 ctagacctcg ttttgctccc acatacatga attcagcatt cggttcttga gtctttacat
    11281 aattgacaaa ggcaagagct ggataaatat gtccccctgt tcctccgcct gtaaccaaaa
    11341 ttttcatttt ttatcgctcg cttctacttt ttctatttta atcggttcac agcttccatg
    11401 aatctgtttc ctctagtttc aaaatttggg tattgatccc agctggcatt cgctggtgat
    11461 aataaaacta catcaccatc tgtactgttt tctaatgcta aaggaactgc ttgttctaca
    11521 gaatcggctg ttactattgt ctcgatgcct gctttttttc cagcatccat caacttttct
    11581 tttgtttggc caaatacgac cattgctttg attcctttta atgaaggaat taattcatca
    11641 aatgtatttc ctctgtctaa tccgccagcc aataacacga ccttagacgt ttcaaatcca
    11701 cttagagcca ttttagtcgc taaaatattg gttgcttttg aatcattata aaattttctg
    11761 ccttggattt ctcctacata ttgcgtacga tgtggtacgc catggaaaaa atgcaacgtt
    11821 tctcgtatag cttcatttga tataccatac aattttgcta cagaaatagc agctagtgca
    11881 ttttctacat tatgcttacc tggtacgcca agttcagata tttccattat tttttctttt
    11941 ttatagtata ttgagtaatc gtcagcatac acaccgtctt ccaacacttc ttttgtcgag
    12001 aaaggcagta cgcgtgcttt tgttctttgc gctaattctt gtagttctga ctgattccag
    12061 ttaaggatca gataatcttt ttctgtcatg tttttttgaa ggttccattt agctttgaca
    12121 tattcttttc ttgtaccatg ataatcaata tgtgcttcat agatattggt aatcaccgct
    12181 atatgagggc ggaaatctgt gattcccatg agttggaagc tagacaattc catcacaatt
    12241 ttatcttctg attttgcttc ttgcgctaca ccacttgctg gatacccaat attacccgct
    12301 aaacgtgcaa ttccttgatc tgctcctgca ttcagtagta gtcctgtcat cgttgttgtc
    12361 gttgtttttc cgttcgttcc tgtaatccca ataattgggc attccgctac ttcgtaagct
    12421 agctcaactt ccgtaattac cggaataccc atttcttggg cttttgctac taaaggatga
    12481 ctgtagggaa tccctggatt tttgaccatc aatgaaaatt cttcatccaa caattcgatt
    12541 ggatgactac ctgttattac ttttatccct aaagaaagca gctcttgtgc ttccggattt
    12601 tcgtcaaaag gttttccatc attaacggtg acaagtgcgc ccaattcatg taataatttg
    12661 gccgcactta ctccgctttt tgcgagtcct aagacaagca ctttcttatt ttcatatgtt
    12721 gatatttttt tcatttcccg tcatctccta ccaaacgatc cataatgtga tcaacgaagt
    12781 cacaatgctg atcaaccaaa aaactgtatc aatcttccac tccgaccatc cgcacatttc
    12841 aaagtgatga tgaattggag acattttaaa aattcgtttt cctgtaagct taaaggaagt
    12901 aacttgaagc atcacacttg ctgtttccat aacatagatc aaaccaatca aaagcaatgt
    12961 ccattcttgg tttagcatta tagaaattgc cgctaaaagt ccgcccaacg ctaatgaacc
    13021 gacatctccc ataaaaatct tggcaggttt tctgttgtag acgaagaaac ccagtaaacc
    13081 tcctaaaaca cttaagcaaa tgattaatac atcatactga tgctgatgcc aagcaattag
    13141 accgtaagct gcaaaagaga tacttcctaa gccagcaact aatccatcga tgccatctgt
    13201 cagatttact gcatttgaaa atccaacaag ccagaagaga gcgaaaatac cataaatgat
    13261 tcctaaaggt agatctagtc cgaagaaatt caatacacct ggataacctt cagaacggta
    13321 aacaagataa aagatgattc cccctagaat ctgtccaatc aatttctgct tcgagttcag
    13381 tcccatgttt cttttcttga atatttttat aaaatcatca agaaagccga ttactccgta
    13441 taacgctaat acaaaaagca agatgaaaag agtaggagtt agctgttttt gccaagctcc
    13501 aacccaaatt cctgtcaaaa tagagccgat cagaaacact aagccgccca ttgtaggagt
    13561 tccggctttg ctattgtgcc actttggtcc ctcctcacga atcgcctgac cttgcttttt
    13621 catttgaaaa taaccaataa atagcggcat tgcggcaatt gtcattgcac aactgctgac
    13681 aatgggaatc aatgcttgtg tccattccat gctcttttct ctcctatttc tcttcttatt
    13741 cttctaaagt aaaactaagt ttgtcttcag tgattttttc atatggagca agttcttgtt
    13801 tgacacaata accatctcca tcaaaactaa cttcaatacc gaggattttc cccagcttca
    13861 tgatatctgc ttttgaccat cctgttacgt caggcatcag cttatcacca ccagtatata
    13921 ggatcagttt ttctccagag atcaactgat caccgttggc agtagattgt ttttgtactt
    13981 ttttaccatt accgatcact acaggttgca gtccactttt ttgagcatca gctgctgcaa
    14041 cgtccgcttc aagattacga taatcggcta cggatacttt ttctgttttt gtttctgtat
    14101 ctgaatcttc ttcagtttct ttaaaatcca ttgcccgttt catcaatgga tttgcgattt
    14161 tagccaatgc cattcgatca tatgtcttag ggtgtttcat tgttagatac aagacatagt
    14221 ctggatcttc agaaggaacc atctccacaa tcgaatacag gtaggctgta tctcctgttt
    14281 gatatccccc tgtatcagaa gcgatttggg ctgttccggt ttttgccgat acattgtatc
    14341 caggtacact atatacacca taagcactac cgtagttttc gctttcgaca acatctctca
    14401 tatattcacg gactttttct gttgtttctt ttgaaaaagg ttgccctaga acttctgttt
    14461 gagttgttcg ctcttctcca gtttggggat ccaccacttt gctgatatat cgaggttgaa
    14521 tcattgtacc gttattcgca atagaagtga aagctttcat catttggaaa ttcgtcacac
    14581 ctaccgcttg tccataagca ctcattgctc ggtcgacaat atttaatgta ggtaaagcac
    14641 cgtttacttc atcatctaat ccagaatgag tactttgtcc aaatcccagt ttttgtaaat
    14701 agttatacca tcgtccgcct aatcgctgtt ccagtatgac catcccgacg ttacttgacc
    14761 atgaaagagc ttgacgcatg gtcagcacac ctttttcacc aaagtcatgg tcattgatcg
    14821 tagcatcttc tacttggatt tttccagatt ggaaggtttc attctcgttg aattctcctt
    14881 cttcgatagc agctgcagta gtgaaaactt tcatggttga tcctggttca taactatctt
    14941 gtaccaagaa attacgccag atagcatctt ttccagtcaa tccttccatt gtttcaggat
    15001 tgaaagtagg tcgttgtccc attgccaaga tttctccggt ttttgctttc atcaggactg
    15061 ctgtcaattc ttctggctga tattcttcat ttacttgatc catcagtgtt tctaaataac
    15121 tttgtagtct gctgtctaaa gtcgtgtaga tatcttgtcc gtcgacagct ttttcttctt
    15181 ctgccactgt acctggcaga ggattttgaa aattatcttt ttgataaata atcttaccat
    15241 ctttaccgct caagatatca ttgtaagcag actccaaacc tagtttacca actaagccat
    15301 tctcatcttt gtctggaact gcgtatccaa taaaatgaga agaaaagacg ccatttggat
    15361 acatccgagc ctgatggtcg acaaaataaa gaccagcgac accttctttt ttcatgtccg
    15421 cttcgatgtt ttgcttggtt tcttgggaga tatttttccc atagctacca aattcaactt
    15481 gatacagctc tttttttgcg ccgtcctcta aaatattcag tgcatctttt ttgtctatag
    15541 aaagattctt atgcaggatt tctgctattt tatcaaaatt cttttcttca acatacagtt
    15601 ttttatcccc agaggtatat gtttttgaga gtatcgcttt aattgaataa gaggaggcat
    15661 cttctgcgag cgccacaccg ttacgatcat aaatcgttcc tctttttgct tttactactt
    15721 cacttccttg gtacaactgt tttgtttttt cagctaatga ggtaccagca acatgacctc
    15781 caataacgat atacgagaaa cggacggcaa ataaaaagaa cattccaata ctcgtagcaa
    15841 ataaaatgat acctactttt ttgcgattgt tcatcggatt tagatttttc ttttccataa
    15901 accgccgaat tttattttta agactcattt acttcacttt ccttaaattg tcgtcattaa
    15961 tagacaatcc tttttcttct gcgatttgtt taatccgttc agtacgagaa agttcgtttt
    16021 tttcttgttc taaactcgtt ttttcttgct ttttatcatt gatttctgtt tgtattgacg
    16081 tgatttcttt ttcagctccg ctgatatttg tgcgcagcat aactgttaaa acacataaag
    16141 caacaatagc aatcgccacg cttgccacag caattttttc caaagcagaa atctgcttta
    16201 atcgttttgc cggtgattgt ggaagaatga tttcttgatt cgaagaagaa tcaggcattt
    16261 gttgttccgg ctgatccacc aattcaggta aatcatattc gtaatcttgc attttcttta
    16321 attctgccat cattctactc ctctttcatt cttatttttt ctgcaatacg taactttgca
    16381 ctgcgtgatc gattgttttc tgttagctct tcctctgaag gaaggattgg tttacgagta
    16441 atgactttca gttctggttg gaattcgtca ggtatgacag gaagtcccgg tggtagatct
    16501 tgtaccgtac tatattcttt aaacatactt ttgacaattc tgtcttccaa tgaatggaat
    16561 gtgattacgc tgattcttcc attgactttc aataaccgga ttgcctgttc taaagaggcc
    16621 tcttcggcac cgagttcgtc atttactgca atccgcacag cttgaaaaat tctttttgca
    16681 ggatgcccgc cttttcttct tgcgggagct gggatgactt gtttaatgat ttcgacaagc
    16741 tcaccagttg tttggattgg ttttgttttt cgtactcgtt cgatttcacg agcaatttgt
    16801 ttggaaaatt tctcctcgcc atagcggaag aaaatcttta ctaattcatg gtaggaatat
    16861 tcattaatta cgtgataagc ggataaagga gctgactgat ccatgcgcat atccaacggt
    16921 gcatcttgat gataactaaa tccacgttct gcttcatcta gctgaggaga ggaaacccct
    16981 agatcataca aaatgccgtc taccttatct acatgctcac tcaagcgttc ttctaattct
    17041 ctgaagttcg ctttgataaa tgtgaccata ccttgttcga cataagaagc taaacgcagc
    17101 ttggcgtgat cgattgcttt ttgatcttgg tcaaacgcat acagatgccc tttagaactt
    17161 agttggctta ataaatattc actatgtccg gcaccgccga gtgtacagtc tacataaacg
    17221 ccatccggtt tgatgttcaa tccatctacc gtttctttca acatgactgt atagtgttga
    17281 aatgtttcag tcattagtca gcctcttcct attcttatag tccgaaatca atcatacttt
    17341 cagcaatttc gtcaaagttc tcttctgctg ctgcagaaaa atcttgccat cgtgtctcat
    17401 cccaaatttc aattcggtta gatacaccga tgactacgca accttttgtc aaagctgcat
    17461 aatttcttaa cgtgctgggt atattgattc gtccttgttt atcaagttcg cattcagtgg
    17521 cagccgaata gaagaatcgc acaaaagtac gtgcgtcttt tttagccaac ggcatttcgt
    17581 tcagtttagc ttccagattt tcccattcgc tcatcggata gccgaaaaga cagccatcca
    17641 atccgcgtgt cagaacaaac ttttcgccaa gttcttcacg aagttttgag ggcacgatta
    17701 aacgtccttt tgcatcaata ttatgttgga attcacccat caacattgaa agccccccat
    17761 tcctccacta actaaaatta gtctaccaca atcccccact ttctaccacc ttttctggga
    17821 aatccgggaa caactttttt tattcataaa cattttttta aaaatcaagc tgcaaaaagc
    17881 cttttaaaag actttttaca gcttttctat ttttttcata ggtaagaaag tatgttcaca
    17941 atgatcaaga cagcgtacaa gacgattgtc aacagaaaaa ccaaacgcca agtcatcttg
    18001 aaataacgcg gataaataat ttcttcataa taatatgctt ggaaaacagc aatacaaatt
    18061 cccattagca aaacagaaat aaagaaaaac ggtaagatag aaattgtccc tgtatttcta
    18121 gacaatgcat gcataccgcc ccacaaaaaa ggaatcgcca aatcaggggc ttttatttta
    18181 aaacgacgat ttaacgaaaa taattttaca agaaattggc aaccaaacaa aacgattacc
    18241 gggtaaatat accaaaacaa gataagtggt gtgaatgtgc ccatgaacgt aaactccttt
    18301 tttatcgttg cttcaagtat actgtatata ctttacacaa ctgtttcatt ttatttaaat
    18361 ttatgcagtt atattctata tcttacaaac acattccatg tattccaatt ccctatccgt
    18421 tataataaaa gaaacaggca acaggaggaa aatcatgatc aaatatttta cattagataa
    18481 tgagaaactg cgtaataccg gaaaggaaac tgaccaaacg atctggtatt gtgtagaacg
    18541 tcctaatcaa gaagagattc atcagctgac acatcaattt gaaattccgt cagattacat
    18601 cacttccata ttggacgatg cagaaaattc ccgtacagaa gaattcaatc aatcaaagtt
    18661 gacaaagcca gcgttattat tgttacaata tccttttgct aaaacaagtc ctagcggtta
    18721 ttttcaagtg gatacatacc cgctctctat tattttgacg cccaaaaaga agcttatcac
    18781 aattacgaat catgaaccac tgtttttaaa gaaagtcttt agccagacct ttccaaaaag
    18841 tgatatttcg cctaatctca atatcttctt tcaattcatt tggcaggtca cactctctta
    18901 caacagttat ttagctacgc ttcaatctca atgcgatact ttggaagcca aacttcaagt
    18961 atccactgaa aacaaacaac tttatcaaat catggatatc caaaaaagcc tcgtttattt
    19021 cagagaagcg acttctgcta atttagatgc attgaaagaa ctagcgcaaa ataaactttt
    19081 ccaagaaaat catgctttga aaaatcattt acgtgatgta ttggtggaaa cagagcaggc
    19141 aatgactact tctcgcattc aattaaaact agtagaacaa atgaatcaga ctttttcagc
    19201 aatcgtatcg aataatctga ataatattat gaaaatttta acttctttaa cgattatttt
    19261 aactataccg acaatcgtcg gcagtatcta tggaatgaac attaagttac ctattgctga
    19321 aagggatgat gcctttatat ggctagttct attaacatta tttatttgta tcgtaactac
    19381 ctattattta aaaaaaggga agtttttata aaaaagccct cttgtggaaa tggaaaaaag
    19441 attgtacact tgaatcaact aattaatgac gaggttgaaa acaatgcgtg aaaaaaaaca
    19501 aacaagtact tttgctaaag taacaaaatt tgtcatttgg acaatgctga ttttaacgat
    19561 tggatctgtt gtattgactg ctgtaatgag tgtcatgtaa aaataaaata tagctatcag
    19621 ctgctgaaaa ggacctgaac cactgcgagg tggctcaggt cctttttgcg agtttcaata
    19681 gttcttttgc atgttcgagt gtgagttttg taatctcact tccagccagc atacgtgcaa
    19741 tttcttcttc tctttctttt gttttcaact ctgaaacaga agtttgcgta cgtccatcaa
    19801 tcactgcttt cacaatataa tattgatagt cggcgactgc agcaacttga ggcagatgag
    19861 tgatgcacaa aacttgagag tatttcgata tttgagaaat tttatctgcg atggcctgtg
    19921 caactcttcc gctcacacct gtatccactt catcaaaaat aatacttgtc acaccttgct
    19981 cagaagaaaa aatagttttc aaagcaagca acatccgaga cagttcgcca ccagaagcga
    20041 ctttcaccaa aggcttcagt ggctctcctg gattggtcgt aatgtaaaat tcgatttggt
    20101 caaatccatc atgattcaat tgtctatttt cttcttttaa gaaacgtacc tcaaactcag
    20161 tgttttccat atacagactt ttcaattcat gcagaatgga tttttccaat tcttttgcga
    20221 tttttttacg cgcttcatga agatctgcgg cttgttgctg aagtagaagc tctttttgct
    20281 ctagttcctc tttcattttg tccaattgac cttctgaaaa atcagaagaa gctagctctt
    20341 cggtgatttc gtcatagtaa gccaatattg actcaatgga ttcgccgtat ttacgtttca
    20401 actgtcggat taattctaaa cgttgcgtaa cttcttctaa acgactctca tctaactcca
    20461 ataaatcaat ctgacgactc atatcgccga ttgcatcttg cagcaaatag taagcacttt
    20521 ggatattttc ataaattgct tcatactcca catctagatg ggcgatccct tgcagttctg
    20581 aaacggccaa gccaacacca tctacactgt tttgttcatt attcgtcagt gctccgtaac
    20641 ctgcagctaa tccatcagca attttttgat aattgctaag tttttctctt tcttctttta
    20701 atttctcttc ttctccgact tgcaaatcag cagcagctat ttcttcttgc tggaaatgga
    20761 gcatatctat tctctgaaca taggattttt cattttgctg cacttttcgt accctttttt
    20821 ccagctcacg ataagagata tattcttgct gataactctt tttcttctgt tggaaagcta
    20881 catctccaaa acgatccaat aaagcaagat gtgattcagg ctggagcagt tcctgatgtt
    20941 cgttttgtcc ttggatatct actaaataac tgccgattct tctcagatta gctaatgtga
    21001 taatatgacc attcactcga caaacatttt ttccagttaa ggacatatcc cgtcgaacaa
    21061 tcagattgtc ctcatctgtt tcgatcccta attcaaccat cagttcagag aatccttctt
    21121 gttttggtag ttcaaacaac ccttcaagca cacatttttc tgctccttga cgtatataat
    21181 cgcttgaacc tcttcctcct gctaacagac ctaaagcatc gataataatg gatttacccg
    21241 caccagtctc tccggtcagc gcggtcattc cttcgtgaaa agaaagccgc aattccggaa
    21301 taatcgcaaa gttagtaata ctgatttctt gtagcatcac attcgctcct caacttaaag
    21361 gtaatgcagg aagtctttct tcaataaaac tgcctggtct tcagttcgtg taatcatcaa
    21421 aacattatcg tcatcattga taatcgaaaa taattctttc ttgtaacgtt tatcaatcaa
    21481 atttgctgct gccgaagcat ttcccggcaa tgttttcaaa ataacaaatt tttccatttg
    21541 gtcaactgcc acgaaagcgt cttttaatag tttttccaat ttagtattta catcttcgtt
    21601 tgtttcagct ggtatgctat aacggtagcc gccatctgaa gccggtacct tgatcagttt
    21661 cagttccttt atatctctgg aaatcgtagc ttgagtaaca gatattcctt tgcttttcag
    21721 gatttcaaca aattcttcct gctttcggat atcttgctca ctcaacaatc gagtaatcaa
    21781 acgatgccga tctttttttc tcattacgtc ttcgctcctt agcatattct tcttaatcaa
    21841 tgatagctta tttccttggt ataataaaga agaatccgca tacttctcac ttgattttca
    21901 cagttacaat ttatttatgg tcaaactgtt cgtgtgcatt tgaaaccact tctgccatat
    21961 taatagctga attgattgtt ccgctttcgg gtactttcct caagtgagcc aagaactcga
    22021 tatttccttc tccccccgtg atcggagaat aacttaattc cagcacatca tatccacctt
    22081 gtgccgcaaa tgacaaaatg tcttctaaaa ctttttgatg ggtctgaggg tcacgaacaa
    22141 ttccgttttt ccctacagct tctctgcctg cttcgaattg gggtttgatt aaagcaatca
    22201 cttctccctc ttcttttaaa atagcatgta atggaggcag catcagtttt agtgaaataa
    22261 aagaaacatc gataacagca acttctggaa ttcctaaggt aaagtcttcg ggttttgcat
    22321 aacgaaaatt cactctttcc attacgacga ctctaggatc ttgtcttatt ttccaagcta
    22381 gctgattgta gccaacgtct aaagcataac tcatttttgc gccattttgc aaagctgcat
    22441 cagtaaatcc gccagtggat gcaccaatat ctaacaatgt ttttccttca acagatagat
    22501 caaatgcttt gagtgctttt tctaatttta atccccctcg agaaacataa ggaagttttt
    22561 tacctttgac tcttaattca ctactcactg gaattttttc tcccggttta tcaaaccgct
    22621 cgtttttttc gttgtaaatc aaaccagcca tcactgaacg tttggcttgt tctcttgttt
    22681 caaataatcc ttgtttgacc gctaatacat ctacgcgttc tttttccatt ctttccctca
    22741 tttctccaca tcaaattgct tgatcatctg gcgcatcagc ccgccatcaa aagaaaaaac
    22801 gtcctcttct aatttgtcta tgatcttgtt ggcggataac agctcaatct ccaacgcctc
    22861 acgtgtcttt tctaggccta ataaacgcgg gtaagtattt ttttccatac gttcatcttt
    22921 accagctgtt ttccctaatg ttttcgttgt accaatcaca tcgagtagat catctcttat
    22981 ctgaaaagct aaacctaaat gttcggctaa tcgttgaagt agcaataaga tttcttcagg
    23041 ttgcttcgct aatatgccac cagccagcaa ggcataacga gtcaaatgcc ctgtctttct
    23101 ttcatgaata aatgctaatt cttctaaaga aagctttttc gattcgccct cgatatctgc
    23161 agcttgccca gcaaccatac cttgtgatcc cgcacaaaca gctaattgct gaagcagcag
    23221 aagcttagga gaattaccta agtgtgccat actgattagc tggaatgctc ctgtaagcaa
    23281 accatctccg gccaatatag ctaatgcttc gccgaatact ttatgattgg taggttttcc
    23341 tctacgaaga tcatcattgt ccatcgcagg caaatcatcg tggatcaagg aatacgtatg
    23401 caccatttct aaagcagctg ctacttgata gacgggaaca tcaataggct catcaaagga
    23461 agcaacggcc gttaaaagta ataagggacg tattcttttc ccgcctgctt tcactgaata
    23521 actcatcgca tcatagagtc ctctatccgt tgtatgctca tctaaaaaag acaagatttc
    23581 tttttctaca gcaggtagat gaatagctga aaagtcagtt aatctcatct cagctttcct
    23641 cgtttccgtc aaaatcaact tcttcatttg attctgtcat cattttcgtc aaggtctctt
    23701 ctgctttagc taatgtatct tggcaatgtt tgcttaattc cattcctcgt ttaaacgaat
    23761 ctagagctga ttctaatgga acgtctcctt gttctaactg catgacaatt ttttctaatt
    23821 cttgcagtga ctcttcaaaa gttggatttt ccatattttt attctccttt gtctatctct
    23881 tgtacttgtc ctttaacgat tccatcttga taatggatcg tcagcaaatc cccttgatga
    23941 atctcggtga cactttttac tacttgatca tttaacgtcg tatagctgta gcctcttccc
    24001 atgattttca atggactcaa caaatcaaga gattgaacag cttgagcaaa acgctgctgc
    24061 tgttgtttca tatattgttg gattttctct tctaagcgtt tttctagata agcagtttct
    24121 tggcgagctg ctttaactcg ataaagcgga gccacttgtt ccaattggtg gcttaatgcg
    24181 atcgtttgtt tttctttcgc atgataaatt tgctgtgtag cttgatataa tcgctgtttc
    24241 aactggtcta atttgatggt ctgaccttca tacaatcttt caggctgccg aaatacatag
    24301 gaacgtcgag cacgctcgaa ccgttcttgt ttgcgctgga tctggcgtac aaacgcctgc
    24361 tgcaatctag cttgccgttc ttgaatgcgc atcaactctt ctgacaaaac aggaacagct
    24421 aattctgcag ctgctgttgg agtggcagcc cgaacatctg ctactaaatc agcgatcgtg
    24481 gtatctgttt catgtcctac agatgaaatc accggcgtat tagcttgata aatcgcccga
    24541 gcaacccgct cttcattaaa cggccataaa tcctcaatcg aaccaccccc acgaccgatg
    24601 atcattgtat cgaaattgcc catctcttct actctctgga tattcctgac aacattgtcc
    24661 gctgcttggt ttccttgtac aactgttggg aacaaaacca attggacaat tggatatctt
    24721 cttttcaccg tcgtgatgat atcgcggata accgctccgc ttggactggt aaggaccgcg
    24781 attcgctttg ggaaacgtgg cagcattttt ttaggccctt gaaaaaggcc ttccttcatc
    24841 agcttttctt ttcgttcttc caattcttga tataaagcac ctattccatc aggctccatg
    24901 tgctctacat agatttgata agaacctccc gcttcatata atgaaatacg cccaacgaca
    24961 aggactttca ttccttcttt tggctggaat cgtaattttt ggaatgctcc tttgaacata
    25021 atagcagata tttttgcatg gtcatctttt aagctgaaat attgatgggc attggcacgt
    25081 aaacggaaat tcgatatttc gcctgttaaa tatacgcgtt ctaaataagg atcggcatca
    25141 aattttcttt tcaaatactt cgttaatgta gtgacagtta aatattcttg tgccatctat
    25201 tcacctgctc caaaagcttc ggcagatttt acggtttgat acatcagcat cgtgatagtc
    25261 attggcccta caccctttgg cacaggagtg atccagcctg caataggctc cacttcatca
    25321 aatttcacat caccgatcag cttaccgtta gcatcacgat tcatccctac atctatcact
    25381 acagcacctg gttttacgaa ttcttttgtg acaaaatgtc cacgtcctat tgctacgact
    25441 aaaatatctg cttcttgtgc cagttcagcc agattttcgg ttttagaatg agcaacagta
    25501 acagttgcat ctgccatcaa gagtagctga gccatcggtt taccgacgat attgcttcgt
    25561 ccgataacta ctgctcgttt acccgccgga tcgatagaat aagcttcaaa cattttcatg
    25621 atgccgtatg gagtacaagg aatcttgtcc ggtttacccg caaggagtct gcctaaattc
    25681 atcggatgaa aaccgtctac gtctttttca gggcggatag ctaacaggat cttttcttca
    25741 tctatatgct ttggcaatgg taattggacc aatataccat gaaaactagg atcttgattg
    25801 tatttttcaa tttctgcaag tagttcgtct tcagaaatcg tctcaggata acgctctacc
    25861 aatgaatgga ttccgatttc ttttgctaca cgttctttat ttcttacata gatttggctg
    25921 gctggatttt cccctaccaa taaaacgact aatccgggat ggataccatt atctttcaat
    25981 ttttggattt tttcagcaat ctctgcctgc attttttcag ctaattcttt tccgttaatc
    26041 aattctgcca tctaaccact cccagatatt ttttgtgttt tcattctacc atagaatttt
    26101 cccgatttat aacaggttta tgatgattca tagaaaaaag ctaggactta cgccccagct
    26161 tctaattctt tcaatacatt ggataaaaca ccgttgacga atttacgtga acggtcatca
    26221 ctaaatgttt ttgccaactc gattgcttca tttaaagcaa cagccgctgg tacatctgtc
    26281 acataagtca tttcaaaaat cgcgatacgc aagatcacca aatccatttt tgagatccga
    26341 ttgatgtgcc aattgttttt taaatgtttt tcaatcactt tatccaattc atcttttttt
    26401 gcacagacac cgccaactag cgtatcaaga taaacaggaa caaactctga ttcatcttcg
    26461 ttgatcatgt cgcggtggtc taattcgatt gcgttgaaaa tcgcatcttc ttttgttagg
    26521 tctgcattga agtctaatgg aaataaagcc tgcaatgcca tttcccgaat ctcgtgtctt
    26581 gataattctt tattcattct cttcctcttc gtcttcaaaa agttcttcga ttgttggttg
    26641 ttctaatttt tcaggaacaa cagctactac atggatattg acttcagata aatcgatatc
    26701 cgtcatgaaa aggacttgct ggctgacccg ttcctgcatt tccattgcta ctttaggaac
    26761 tgaaacacca tattctagat aacagtaaag atctactttc aagccatctt cctcgtttgc
    26821 taagtaaaca ccttttccgt gagctgcacg tcctaataat tcagtgacat tgctggcaaa
    26881 agttccgcgc attccgtata cgccttctac tttagaagct gcaatcccga taattacttc
    26941 gatgacttca ggagcgatca cgatctctcc taaatcttgg tttgcgttta aaatcaaatt
    27001 tttttcatct gccatttatt tattcctccc tttgcctaag cacgagatac atccgaattc
    27061 tctatgatgc ggcatagtga tcacgtggta agaaaactgc cgccgatcag ctgcaaactg
    27121 ctatgaattg gagaaaacac ccaactttat tatctcttac agcttaaaag ttcttctata
    27181 gtgtatcatt aaatcgagtg attttctata acaaagtctg tgaacactga tttttacgct
    27241 tacttcttct attgatgaaa ctataagatg atcaattctt ttggtgaacg agtcaacaca
    27301 cgatttccat cttctgtgat caacaagtca tcctcaatac gtactccacc gattcctggt
    27361 aagtagatcc ctggttcatc agtgatcaca tttcctggta caaattgctt ttctgcacga
    27421 gaagaaacgt ttggtccttc gtggatctct aaaccgatcc catgtcctgt agaatgtcca
    27481 aatgcttccc cgtaaccatg ttttgaaata taatctctag caactgcatc taattggaca
    27541 ccagtcattc ctggttttgc agcatcaata actgctaatt gagcatctaa gactatttga
    27601 taaatttctt ttaatttttc cccaggatca ccaatagcga atgtacgtgt catatcggaa
    27661 acgtaccctt cgtaatagca accaaagtcc aatgtgatca agtcaccttg ttcgatgatt
    27721 tttttgcttg ctacaccatg cggcatagcc gaacgcaatc cgctagcaac gatcgtatca
    27781 aaagaaacac ctgaagcgcc aagagaacgc atataaaagt ctagttgatt tgcgacttca
    27841 atctcagtca tgcccggttg gatcattttc aggatgtgat catatgccat atccgcaata
    27901 tgacatgctt tttcgataat agcgatttct tcttcatctt tcacttctct gagttcttcg
    27961 atcatctgtg aaacaggtac taattccgca tcgatgattt cttctaaaac cgaatattct
    28021 aaaaatgaga ctgttgtttc ctcaaaagct aatgagtgca gttcttcttt gcgtactaag
    28081 tttgctacct catcaaaaat aggtccgaca tttttaataa tttcaaaccc ttgagcctgc
    28141 gctgccgcct gctcggtata acgaaaatca gtaataaaaa atgctttttc caaagtaata
    28201 acagctaatc ctgtcgtacc tgtaaagttc gttaagtaac gaagattgta cggactggta
    28261 accaaaaatg aatccaaatt ttcttcttgc atttttttgc gcaatttttc tacacgtagc
    28321 atcataatga aactccctct ttctttgcac gcttttttcc attatagcaa acttttcttc
    28381 gtacacgaca gttaaataaa aatttccgga aaacttcttt ttattttaaa taaataaagc
    28441 caaaaaggag tcacagtctc gctgcaactc cttttagttt actattttgt aaaaacttat
    28501 gatcgttttc caaagaaaaa tgagacaact gctaccaaaa tcactgcgcc taaaatagat
    28561 ggaataagtg ccatacctgc agcttttggt ccccattcgc cgaaaatcgc ttgtccaata
    28621 cttgaaccga ctagtccagc aatgatattc gttacacagc ccatcgaatt tcctttactg
    28681 gtgatcgcac ctgcaattgc tccgatcacg gctccaacaa tcaatgtcca taaccaactc
    28741 ataatataac ctccttcttt gctaatcaat tttagcatat gggatttaaa ggggacaaat
    28801 aattggtttt gctatttcat attttcttct gcaaagtaaa aaaataaaga aaacctcctc
    28861 ttagaagttt tctttatttt ttacttgcgt ttaaacatac tacgaatacc acgtttcact
    28921 acatcaaaga aactcaatga ttgtaccatt ctatcttcat ctacatattc tctgatcgca
    28981 cgaagcactt ttttaggttc tttggaagaa aatgtgtatg taccattttt tttcgtttga
    29041 atggcatatc gaggaatcca ttttcccttt agcatgactg atgctagtac ataatccact
    29101 tcttcccatg gaatttggat atatttgcgt ctatctcgcg catggtaaaa ctcaaaacca
    29161 ttatcaccta tcatgatttg cccgtaatct gtcagacccg taaacgaagt agcatcaatt
    29221 accaagtcta cttttgtatt gattgattga accattttct ccctccagat atttgtttat
    29281 gaacagtata ctatataaaa aaagctcggg acaacgcccg agctatattt ttatggatta
    29341 taaaagtccg atgacgtgtc caacaacacc gactacgaat aaaccaagga tgataacgat
    29401 tggagaaacc tttttcttaa gcaaccacat acataacaat gttaatccta atgcagctaa
    29461 accaggaatc aattggtcta agttgtcttg taatgttgtt accttttcag gagaaagggc
    29521 taagccatta ttaacttgtt caaatgcact cttgattcct tcaccacctg aaggcaattt
    29581 atcccattcg atgtaagcac ctttatctaa ttttacagtt gatacaactg gtaagaattt
    29641 gattgatacc catctttcta caagggcagc taatacgaac atccctaaaa ttgaagcacc
    29701 ttttgttacg tcttgtaaca atccgccaga aaggtcatca gtaattttag aaccagcttt
    29761 gtagccaaat tcttgtgtat accacatgaa tgcccaacga ataatgttcc aacctaagaa
    29821 gaagatgatt ggtccaagga tatttcctcc catagctaat gaagcaccta gtgcacctag
    29881 cattggacgt actgtaaacc agaacactgg gtcaccaaca ccagctaaag gacccatcat
    29941 acctacttta accccttgaa tcgctacatc atcaacaggc gcgccattcg cacgttcttc
    30001 ttccagagcc aatgtaaccc ctaaaattgg agaagcaatg tatgggtgtg tattaaagaa
    30061 ttccaagtga cgttttaatg ctgcagaacg ttcttctttt gttttgtata attttttgat
    30121 tgctggaatc atagaaaatg cccagccacc gttttgcata cgttcgtagt tccatgaacc
    30181 ttgaatgaag gtagagcgcc acgcaacagc taaacgatct ttttttgata atttgatttt
    30241 ttcttctgcc attttatttt cctccttcaa gattaatagt cattcaaaat gtcgcctaaa
    30301 gggtcaccag agttgcttcc gcctccatta tttgatgaac cacccatttt agaaaggttc
    30361 aagtaaataa gagctaatgc aacacctaaa gcacctagag caatcaatgt taattgagaa
    30421 attgcagcta caacgaaacc aataacgaag aatggccata cttcttttgt agccatcatg
    30481 ttgattacca aagcgtaacc tacagctacg accattcccc caccgatagc cataccatct
    30541 gttaaccatg ctggcattga ttcaaggaat gattgcacag tttgtgctgg gataaatagc
    30601 aacgctgctg ctgggaccgc gatacgaacc ccttgtaaac atacagcaat gatgtgccac
    30661 atttcaacct tacggatgtt tccttcttca gcagccgcat ccatcaaatg aacgattgga
    30721 acagcgattg tacgtacgat cattgttaag aacaaccctg caacagccaa aggaacggca
    30781 atcgcgatcg cagaaggaac acctttaaca ccttgtccac ctaaaactaa aataattgct
    30841 gatgctactg atgctaatgc agcatctggt gctacagcgg caccgatatt tgcccaacct
    30901 aaagcgatca tctgaagcgt accgccaagt acgataccag cttcgaggtt accggtaact
    30961 aaaccgatca atgtacatgc cactagtggt tgatgaaatt gaaattcatc aagaatacct
    31021 tccataccag ctagaaaggc aactaatacg actaaaatta ttgaaataat agacatgata
    31081 agcctcctat aaattttaat attatttatt acgcttttgc taattcagct tttgcttttt
    31141 tcaaaatatc atccatgtta tcgcgtgaat cattaggtac tttacgtaca tcgaatttca
    31201 cacctttttg ttcaagcttc tcaaacgctt caacgtcttc ttgtcccata gacaatactt
    31261 tacttacaac gactttaccg accgaatgcg ccattgaccc aacatttaat tctttgatgt
    31321 ctacgccacc ttcaacagct gtcaatacgt cttcaggatt ttcaaataaa agcaatgctt
    31381 tggtatttcc aaaacgaggg tcttttgcta cttcgatcat tttgctaata ggaataacat
    31441 ttgcttttac acctggagga gcagcttgtt cgattagtct cttacgcaga tcatcctttg
    31501 atactgcatc tgaaacaacg ataatacggt ttggttgcac tgcttttgtc caagctgtcg
    31561 caacttgtcc atgtaacaga cgtgagtcaa cacgtgctaa tacatatttg atttttccgt
    31621 ctccgaccac agttccttct ggaagtgctc ctttaggttg tgcgtcttca actgctgctt
    31681 tcggtgcttc tgccggttct aattcttccg gttttacttt tacaccgtct tttgctgttt
    31741 caatgatgtg tgctgcaatt tcatgagcag attccattga aaagcgtgat gcgtaggctt
    31801 caatcaacat tggtaaattc aaaccgctga cgattgccca tttatctttg tgctcttcga
    31861 ataatgtgtt tgattgattg aacggtgttc cgccccataa atcaactaag aataacactt
    31921 cgtcttgatt atcaaaagaa gcaaccgctt cttccaattt ggctctcaag tcatctggac
    31981 cttcacttgg tttcaaaatc acggctttga cgttttcttg ttcgccaaag atcattgaac
    32041 cggattgtaa gattccttca gcaaattgtc catgacttgc taggataatc cctaccatat
    32101 ttatacctcc tatttacttt tgttgtaaca aattcaaaaa tattaataat tgctaaccat
    32161 tacaacagaa ttatttgacc ttttccaaca accattcttg ctacaccttt ttgattttcg
    32221 ctagtagttc catcaaaagg attttcctgt cagcaggtac ttttcgaatc tctaactcca
    32281 cttcttgact gttcaagtaa cgaaaggaat caatatcttg ttgatttact gaaacaaaat
    32341 tggtaatcat tgatttgcct tcagtaaaac tcataccgcc gatattcaac gacttcaact
    32401 gtacaccgca gcggacaacc gcttcaacat cttggggatt ggtgaataaa agcatcactt
    32461 ttgctcgtga taataatcca ctatgataga tttgaatcat tttctgcacg gttattacat
    32521 ttgctgtgat ccccggcggt gcagcttctt ttagtagaaa ctttctcaat ttatcttgag
    32581 cgactacatc gctgatcaca atgatacgtt caacacctgt ttgcttcgac caaactgttg
    32641 cgacttgccc gtggattaaa cgatcatcta tacgtgccaa tcgaatatcc atctgcaaaa
    32701 ctccttcttc ctcactactt cacagaaacc cctatcattt ctgtgtgaac aaccacctcc
    32761 tagcacacac tactataagc aaaaagcgtg ccaacttttt tacgatacac taattgaatt
    32821 taaaggattc ttaaccaata cacaaaaacg atacactata aaagtgtatc gtttttgtgt
    32881 attcatggca cagtgtattc ttttttatct aactgattat ggactagacg tagcagataa
    32941 tacatttctt ctatcggcac ttttactttt atctgatctt ccaacagaac aactgaggct
    33001 gccaattggc tataaagagg atcattcgtt gtatttgtca attcgttttc ttccacagtc
    33061 aatggttcat tccgaataat acgttcgatc attcctgctg tgtgcatcac taggttgatt
    33121 ttgaatccat attcttcatc gccgattccc gtcgtctgag agatttgtgt agaaaattgc
    33181 cacattggat cgattaactt actaccatta ataaagatga agttatcaga gataaactca
    33241 acacacgtat ttttagctga ctcttcatct agggagatga attcagtttc ctccaattct
    33301 gattccatca gcaactgatc caaaatgact tcgatatttt gatcaataaa acgttctaaa
    33361 ggaataaatg gggcttggat attcaaatca gtaatcccag tagtagctat gatctgatat
    33421 tctttttgga taactggcag ttcttctttc acttccacaa tcgacaaagc tagaacttct
    33481 aattctgttt cttgacgctt gtttaccgct cgttcgatca attctttgat tctttgtgct
    33541 gtaccttcgc cagatgcgca gatagccaaa acagcttttt tcttatgaat aggttttgct
    33601 tcctgaacag attctacaga agatatttct gcgtaacctc gaaaattttt caatgattca
    33661 tgcaacatat ctagatctgt ccctaatact gagacctttc gtacagtttc caaaactaga
    33721 gaagttgtta ccatatcaac agtacgtact ggaattccag tgtctctttg aatttgcgaa
    33781 ttaaacgacg caagggaccc catatctact aagagtatga ccccgcttcc ttcatctact
    33841 tcttgtacat tgcgttcaat tcggtccaat gctgttttcg gatccatatc caaaggcatg
    33901 tctactgctc gtacgttctc tgcatctaac aactgttgga caacttggac catactgctt
    33961 gctgtgctgt ttccgtgagc tgcaacgact acaccgattc tgccgcttgc ttgatttgcc
    34021 cgtaacgaga cgagtagaac ggtcaagtaa tagtcttcac tttctggaat ctccacttga
    34081 aaatacgttt cgatataact acgcacttct ttcgcaacag catattcatc tggaaaatca
    34141 aaagccatct cacggatgtt atcattcgta tgccgttctt ctcctaagtt gatttttttc
    34201 aaaaaagaac tgatatgcaa gctcatagca taaataaagt tttgctgaaa ctcatatggt
    34261 aaagatcttt tgaccattac ataaatctga ttggtcactt ctatgatttt cggatctaca
    34321 aattctgcta atttgctgtc tgcattaaaa gaaaaaccat ggtctttata gaaagacttc
    34381 agatggatgt tgatatctgt agaaatgaaa tgattgattg cttcttgatc caaaccatcc
    34441 gacttcagta aagctgcttt atctccgatg atatcatata gattataagg taactcatag
    34501 gagtccgatt ggattttcat gatcgtatca tttggtgcta cagttatctt tggctccaat
    34561 attttagaaa gctctgccat tgcactgcgg ttgcttgcta attgaatcaa tccgctacga
    34621 atcccttctg tcaaatcatc gattgtgatc gagatttcgg gtgattgcat atgatttaga
    34681 aatcctcgtg cacatactaa ctggatattt gacttcaatt gtcctatatt tccataggtc
    34741 acactgccga tcaatgcttt tgctacatct tctgtcaaag aaatctttcg ctgcgtgcgg
    34801 tttgcttcgt gggcaatcat gatttttact aaatcgactt tctcatttgc aggacgtttt
    34861 tcaaaagccg gaagtttgat attgattggg atacgccgaa caaaagtttc taatagagaa
    34921 gaacctgggt cttctgtggt cgcacctacg atccgtacat ttgcttcatg ggatttcgtt
    34981 gtttccccaa gacgactgta agttccatga tccataaagt aaaagatcat ttcttgacct
    35041 tcaggcggca accggtgaat ctcatccaaa aacagcatac cgccatccgc ttgatcgata
    35101 atccccattt tttcttcatc tgcgcctgta aaagcacctt ttgcgtaccc aaataaatga
    35161 ctcatcaaaa gctcagggtt attggcataa tcagcacaat tgaaaacaat cagttccgtt
    35221 tcctcatcta ttacatgatg cgcttttgca aaatgataca tcgcgtgtgc aaaataagtc
    35281 tttcctgatc cggtaggtcc tgtaatcaaa caatttaatc ctcttggcgg atacaaaatc
    35341 gcagcttttg cctgttccac tgaatttttc atgctgccgt tagctccaat gatttttgca
    35401 aagatatcct tagtatctat ttggagtgta tttttttctt cagagaccgg cgtttctttg
    35461 taactgacta catgttttgt aactggcttt acgtgcgtaa cgagtgtttg atatatgtaa
    35521 cgtactggtc gtccgtctgt ctttatcagt tttccttcgc gcactagctg attcagatct
    35581 ttactgctat ttgttcgctg aatccctaac acttcagcaa tttcctgtgt tgttactcct
    35641 tgatcatatt ctgcctttgt taaatgagcg gttttttctt tgacatacat ataaattcgg
    35701 tcaatgcgtt ttgccaatgg tatcgctcct tttctataga ctattgtact taggcttcaa
    35761 aacataatac tatgtattta tttctgtttc gtcaactatt tacctgattt tgttttgttg
    35821 ataacacgcg gatagataga aatgttcaat ttaaaagaac gaaaaatccc gatacgattt
    35881 ttataatgga aacaagaaaa agaacactgt ttaccatata attatttcac tgatagcaaa
    35941 caatatagct tccatcaatt gaaaacgata gttatcaaaa catcctgatt ccaaattggc
    36001 aaaaaaatat taagtgtaaa aagacaaagt aaacttcgta gcctccacta caacttttat
    36061 ttttataaac aaaaaaggct gtgacaaaag tcttgtcaca acctctttaa tcataagatt
    36121 caattaagct tcttgagcta ctggataaac agacacttgt tttttgttac ggcctttacg
    36181 ttcgaaacgt actacgccat caacttttgc aaataaagtg tcgtctccac cgatacccac
    36241 gtttacacct ggatagattt ttgtaccgcg ttgacggtaa agaattgatc cacctgtaac
    36301 tgtttgtcca tcagcacgtt tagcacctag acgttttgat tctgagtcac ggccgttaga
    36361 tgtagaaccg ccaccttttt tgtgggcaaa taattgtaga ttcatagata acaacatggt
    36421 ctgcacctcc tatttatcat taattgtttt aatttggata tattctgagt tttcagcttc
    36481 tatcgattgt aatcctaata aaagattttc taatagaatc tcagcaatat tgttttgttc
    36541 ttgtgtcatt cctgaagtga cttcggtata aagataaccg ccttcttctt cattcatttc
    36601 aacaatcggc tcaaaaccgg ctaatgaggc aatcccgttg acagtgctga tcgctaacgc
    36661 agaaacaccc gcacaaacga tatcacttcc ataaggacca gcatcagcat gcccggtcaa
    36721 agtgaatgaa acgatctgac ctgcgtcatt tcgcttaaat gttcctttga tcatatatag
    36781 gccttctttc tcaaacgcta ttaagcgttg atcgcgtcga taaccacttt tgtatatggt
    36841 tgacgatgac cttgtttacg gtgtgaatgt tttttaggtt tgtatttgaa agtaacgact
    36901 ttcttttgtt tgccgtgttt ttcaacagta ccttcaacag ttgcacctgc aacagttgga
    36961 gcgcctactt ttgtagattc tccgcctact aagataactt cgtcaaaaac aactttttct
    37021 cctgcttcaa cgtcaagttt ttcaacatag attgcttgtc ccacttcaac ttttacttgt
    37081 ttaccaccag ttttaataat tgcgtacatg ctataaagca cctccttctg atatacttag
    37141 actcgccatc cgaagtgaca gcatatgctg tgcttattac ttgttctgag cggttgtagc
    37201 tgtggagtcc acaattacaa cagtactagc ttaccagaac agcaaccgtt agtcaactaa
    37261 atttaaaatc aaaaagtaaa acaaaaattc aagcaatact tctgcttttc tatcctcaca
    37321 gttctaccaa ataaaatagt cgcattgtgt ttcttttatt cttataataa aagaaaaagg
    37381 aggagcataa atggaatacc caaaagaact gatacaagaa gcttctttaa gaatgaacgg
    37441 ccgtcctgta gaaggattta tcgctgggca aggacctctt catcctaaac tgatgctcgt
    37501 gggagaagcc ccagggaaaa cagagattga tacgcatgtt ccttttagcg gtcaagctgg
    37561 aaaagaattg atgcaggcac tttcttcaac tggcttaaca cgagaagagg tgtatatcac
    37621 cagtgctgta aggagccgcc cgtatcgcgt gactcatcgg atcaataaac ggacacaaca
    37681 gtcagaaact gtttatccaa atcggacacc tactcgttcc gaagtatttg cgcatgcacc
    37741 aatattggat tacgaactga tgaaggtcca gccaaaatta attgcgacac ttggaaacat
    37801 tggtcttcaa cgtttacttg gcaaagaata tacggttacc aaaaatcatg gtcaactcta
    37861 tacagggcct gtcttacaat taacagaaca aaaggatgcc tacgaatggt cagaaaaaaa
    37921 ctatcgaatt cttccacttt ttcatccagc agctattttc tacaatcgct cccttgtacc
    37981 tgttatccat caagactggc aagtactagc ttcactttta cagcaatatt aaaaagaaca
    38041 gacaagacca taaaatcttc agtttacagt cttgtctgtt ctttttcatt gttttaatgg
    38101 ctaattgcag tatatttcgc atgtaaagct gtcaacgcat gagcaactgt ttgatgttga
    38161 tgcgtgaatg tatgttccca caagtgagaa agttgttttt ctacttctgg ctgcaaggaa
    38221 gtatagataa tcgtttgtcc tctttgctct gctttttctt gaaattcatc aaaaactgca
    38281 cgtgccgtca aatcaatact tggtacgcct cgcatggaga aaatgacacc atcgtgatga
    38341 tttagttctt ccaatttatt tttgagtttt tctgaagaca taaaaaacag tggaccacta
    38401 atatacacta ctgtccagtt attcagcttt tccgtttctg gcagccccat tctttgccaa
    38461 tcgatcgttt ctaatgaaat cgtgatagca gcgcttttga caacaaaaaa tacacagccg
    38521 ccgatcaccc cgatcacgat agcaatactt aaatcaaaga taactgtaca aatcatcgta
    38581 aggataaaca atagaactgc tgaccaatat ttattagtaa atagctcctt gatcgtttcc
    38641 cattcattca tacgccaagc cgtcacaatc aaaacacctg caagtgctgg cattggaatc
    38701 tgtgacatca ctggcgcaaa aacaagcatg gagagcagta agacaactgc atgtatcata
    38761 ccagctaatc tagtttgtgc accagatttg atggccacgc ttgtacgggc gatggccgca
    38821 gtagcaggaa tcccgccaaa gaaaggaagc aacagatttc caattccttg cgccattaat
    38881 tcttgattgc tatctaaggg cttatttgcc attcggccag ccgaagcacc acatagcaag
    38941 ctttcaatca ttcctaataa agcaatgcta atagctggaa ctgccacttg ttgcaaggca
    39001 gaaaagctaa aatctcccat attcaaacga ttactactga tcaatgtttg tggaatctta
    39061 cccacagttg ctactggtaa atggaacaat agcataactg ctgttgccaa aatgatagcc
    39121 agcagcgaac taggcattcg tttcgcccat ttttttggat agataaacat ccctaaaatg
    39181 actagccctc ccatgatcaa agaggctgtg tttatcggaa atcctatcgt ttgataacta
    39241 cttagttttt caataacgtt tgtaccttcc gagtgaacac caaataaatt atcgatctga
    39301 cctaatgcaa taatgatagc aatacctgaa gtaaaccccg taattacggg tgctgggata
    39361 aaagaagtca gtgttcctaa tcggaaaagt cctgctgcaa gtaaaaatag acccgctaaa
    39421 aaagtagcaa gcaatacacc ttgcattccc tttgttgccg caatagacat caagatagct
    39481 gccatcgcac ctgtcggacc tgatatttga taaaaaccgc ctgataaacc gccaataacg
    39541 ataccggcaa tgatagccgt aatcaaacct gcggccgcat cagctccgct tgatacccca
    39601 aaagccaagg ctaaaggcaa tgctacagca gctactgtga tcccagccaa aagatctttc
    39661 tgaaatcttg aaagatcata acctgaaaat tcttttttta gtgaggaaac ataatttttg
    39721 aacacctatc taactccttt ttcatgaaat tttctaaaat accattcatt agaatatcat
    39781 atttcatgag ataaagtaat atttttcaca aagtttcctg ttagataaat tcttattttt
    39841 tctatattta taagaaaata gaaagcaatg ccaacagagc tagcccacct tgtttgagta
    39901 aaatccaacg atcgctagtc aaactgccat ataatgcaac aaaaaaaata gatattaata
    39961 gcatacttgt gatttcttta gatgcggaag aaagataagc tccataaagt agtcccactc
    40021 ctaatagtcc attgtacact ccttggttct taaacaatgt ttgaacagat tttctgctta
    40081 actcttcttt actcatttta aaaaccctac ttgtcgtgtc agaatcagtt ctcaccgttt
    40141 cgatatacat gatataaaaa aattcaattg caactagagt cactaaaatt ctagatagta
    40201 tcgtcatatc ttcttcctct tttctgatga gttttatttt tttgctcctt ataattgtac
    40261 tcgataagga tgttttttta ttttatttgc ctttgaaaac aaacaatatt ggcacaaaaa
    40321 acaaagaaaa accgttagaa acctcagttt ctaacggttt tttagcgtca caggagggat
    40381 tcgaaccccc gaccgtccgc ttagaaggcg gatgctctat ccagctgagc tactatgaca
    40441 agaatcagcg gaacatcaat aattatagat aattaaattg cttctgtcaa tacgaaatag
    40501 ttatttaatt agcaaataat gaattatttt ggcccaacta ctaaatcaat cttttaaaac
    40561 gagacattct ccttcagctg ttctaaggtt atcaattgaa aacaggagct acattgactt
    40621 catgctactc ctgtttattt agatttcctg tatcctttaa ttgacttaca aatatagaaa
    40681 cttttacatc aagttcgaat tgagccctcg attcaatcga ttatctacag gctgccataa
    40741 tcatgtatca caactcgatt gtttctgatt cctttgtcat taagatcaca ccatcaccta
    40801 atggcaagat tgtcgatgtc aaatcgggat gatccatcac aacacgaaga aattcattta
    40861 atttacgatg gatagctcgt ttgccacggg gaatctcttc atctgggagc aagatcgttc
    40921 ctccttggaa gatgtcatct accatcaaaa cgccaccttt tcttaacaaa cgtaagcatt
    40981 caggtaaaaa ttcaatatat tttgattttg cactatccat aaaaataaag tcatacggac
    41041 cagacaactc cggcaagata tctgctgctt gaccttcaag caaagtcact ttatctgtca
    41101 gtcctagacg ttcatagttt tttttagctt tctcgatcat gacatcgaaa cgatcaattg
    41161 tcgtaacatg agcgttttct ccgattgtcg tggccatgac acttgatgaa aaaccgatag
    41221 ctgctccgat ctccaagatt cgttcaggct gaagctgtcc aagtaaaaat ttcaaaaata
    41281 caactgtttc atggggaata actggtactt ctgctacatg agcttcttct tccagtttgc
    41341 ctagctcacc cggtaatttt ttttgctggg tacgcataaa atccaatagt tcttctttga
    41401 ctacaggacg atgcatcatt tcattgcgca tactactcct cctcttcaca cattatacga
    41461 acaactgact aaatctacaa gctgcatgag tgttttctcg tgtttcatgt tcagaagagt
    41521 cgttggatct ctggaataca tttatgtttt taacattctt acaaaaattt ctgtgttcgt
    41581 ctccgcttct ttttcaactc tacaaaggta ttccatgctg tgattcctgt taggcaaaaa
    41641 gcaatcgtaa agaataaccc ctgaatccat gcaaatgccg tttttgaaag gactagtcca
    41701 atatatggaa tctgaaagat gggactaccg ataatatttc tcttttttac tactccaggc
    41761 tcaatataag tctttgtatc agcttttgta taaaaatctt cgtggttgtt ttcaacggct
    41821 attacgcgac gcgtcgagat tttttttcct gaattttcat aatatgtaat aatatctccg
    41881 actaaaatct catttgtatt tttcggtcgt acatatatca gatttccttg tgcataatat
    41941 ggactcattt ctttgtcctc aataatataa ggagtcaaac caaaaattcg gggaaccaag
    42001 acgacgagaa gaataagaat taaaaatata atcaacgtta tagaacttat aaaagttatt
    42061 tttttgtaat
//
LOCUS       DADQCX010000014        41048 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.014, whole genome shotgun sequence.
ACCESSION   DADQCX010000014 DADQCX010000000
VERSION     DADQCX010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.014"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            79..1125
                     /locus_tag="J8R83_000701"
     CDS             79..1125
                     /locus_tag="J8R83_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAZ9573855.1"
                     /translation="MTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSG
                     NEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNY
                     NLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGN
                     KDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMS
                     KTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNY
                     VVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLS
                     QSMLVDPKTLLFGD"
     gene            1474..2106
                     /locus_tag="J8R83_000702"
     CDS             1474..2106
                     /locus_tag="J8R83_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAZ9573856.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2695..4134
                     /locus_tag="J8R83_000703"
     CDS             2695..4134
                     /locus_tag="J8R83_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9573857.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4429..4647
                     /locus_tag="J8R83_000704"
                     /pseudo
     CDS             4429..4647
                     /locus_tag="J8R83_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4896..5111
                     /locus_tag="J8R83_000705"
     CDS             4896..5111
                     /locus_tag="J8R83_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573858.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5328..5584)
                     /locus_tag="J8R83_000706"
                     /pseudo
     CDS             complement(5328..5584)
                     /locus_tag="J8R83_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(5771..6682)
                     /locus_tag="J8R83_000707"
     CDS             complement(5771..6682)
                     /locus_tag="J8R83_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9573859.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6701..7705)
                     /locus_tag="J8R83_000708"
     CDS             complement(6701..7705)
                     /locus_tag="J8R83_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAZ9573860.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7702..9825)
                     /locus_tag="J8R83_000709"
     CDS             complement(7702..9825)
                     /locus_tag="J8R83_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9573861.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(9830..12277)
                     /locus_tag="J8R83_000710"
     CDS             complement(9830..12277)
                     /locus_tag="J8R83_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9573862.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12264..12653)
                     /locus_tag="J8R83_000711"
     CDS             complement(12264..12653)
                     /locus_tag="J8R83_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9573863.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12713..13216)
                     /locus_tag="J8R83_000712"
     CDS             complement(12713..13216)
                     /locus_tag="J8R83_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAZ9573864.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13229..13453)
                     /locus_tag="J8R83_000713"
     CDS             complement(13229..13453)
                     /locus_tag="J8R83_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573865.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(13557..15467)
                     /gene="ltrA"
                     /locus_tag="J8R83_000714"
     CDS             complement(13557..15467)
                     /gene="ltrA"
                     /locus_tag="J8R83_000714"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAZ9573866.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(16213..16332)
                     /locus_tag="J8R83_000715"
     CDS             complement(16213..16332)
                     /locus_tag="J8R83_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAZ9573867.1"
                     /translation="MGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKGK"
     gene            complement(16347..17531)
                     /locus_tag="J8R83_000716"
     CDS             complement(16347..17531)
                     /locus_tag="J8R83_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAZ9573868.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(17790..18080)
                     /locus_tag="J8R83_000717"
     CDS             complement(17790..18080)
                     /locus_tag="J8R83_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573869.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18070..19212)
                     /gene="dcm"
                     /locus_tag="J8R83_000718"
                     /pseudo
     CDS             complement(18070..19212)
                     /gene="dcm"
                     /locus_tag="J8R83_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19445..20119)
                     /locus_tag="J8R83_000719"
     CDS             complement(19445..20119)
                     /locus_tag="J8R83_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9573870.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20197..21537)
                     /locus_tag="J8R83_000720"
     CDS             complement(20197..21537)
                     /locus_tag="J8R83_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAZ9573871.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(21620..21955)
                     /locus_tag="J8R83_000721"
     CDS             complement(21620..21955)
                     /locus_tag="J8R83_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAZ9573872.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(21965..22339)
                     /locus_tag="J8R83_000722"
     CDS             complement(21965..22339)
                     /locus_tag="J8R83_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAZ9573873.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(22352..22666)
                     /locus_tag="J8R83_000723"
     CDS             complement(22352..22666)
                     /locus_tag="J8R83_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAZ9573874.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(22779..26006)
                     /gene="fss3"
                     /locus_tag="J8R83_000724"
     CDS             complement(22779..26006)
                     /gene="fss3"
                     /locus_tag="J8R83_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAZ9573875.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            26794..27117
                     /locus_tag="J8R83_000725"
     CDS             26794..27117
                     /locus_tag="J8R83_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9573876.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            27281..28198
                     /locus_tag="J8R83_000726"
     CDS             27281..28198
                     /locus_tag="J8R83_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9573877.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            28191..28973
                     /locus_tag="J8R83_000727"
     CDS             28191..28973
                     /locus_tag="J8R83_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9573878.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            28974..29654
                     /locus_tag="J8R83_000728"
     CDS             28974..29654
                     /locus_tag="J8R83_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9573879.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            29647..30543
                     /locus_tag="J8R83_000729"
     CDS             29647..30543
                     /locus_tag="J8R83_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9573880.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            30701..32677
                     /locus_tag="J8R83_000730"
     CDS             30701..32677
                     /locus_tag="J8R83_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAZ9573881.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
     gene            32678..33124
                     /locus_tag="J8R83_000731"
     CDS             32678..33124
                     /locus_tag="J8R83_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAZ9573882.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            33140..33454
                     /locus_tag="J8R83_000732"
     CDS             33140..33454
                     /locus_tag="J8R83_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAZ9573883.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            33480..34529
                     /locus_tag="J8R83_000733"
     CDS             33480..34529
                     /locus_tag="J8R83_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAZ9573884.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            34541..37144
                     /locus_tag="J8R83_000734"
     CDS             34541..37144
                     /locus_tag="J8R83_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAZ9573885.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            37261..38910
                     /locus_tag="J8R83_000735"
     CDS             37261..38910
                     /locus_tag="J8R83_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAZ9573886.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            39226..40161
                     /locus_tag="J8R83_000736"
     CDS             39226..40161
                     /locus_tag="J8R83_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573887.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            40154..40924
                     /locus_tag="J8R83_000737"
     CDS             40154..40924
                     /locus_tag="J8R83_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573888.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
BASE COUNT        12497 a         7849 c         7677 g        13025 t
ORIGIN      
        1 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
       61 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      121 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      181 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      241 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      301 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      361 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      421 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      481 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      541 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
      601 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
      661 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
      721 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
      781 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
      841 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
      901 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
      961 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1021 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1081 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1141 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1201 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1261 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1321 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1381 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1441 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1501 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1561 aatgaaacga ttgtatatcg atcaaactta ctatcaggta gaaccaaaag ttgtggatgt
     1621 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     1681 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     1741 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     1801 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     1861 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     1921 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     1981 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2041 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2101 aaatagattg cgtatataac tttaaaaaaa aaagaggtac tatttaggat cgtatgattc
     2161 tattaagagt gcagctcaag ctagaaaaga tgctgaaaat aaattgtttc aacctttgat
     2221 tgacaaatat cgaggtaatc attaattatt gtggataata attaacagtg atatataaac
     2281 atctataata tattattcat actattgata tttagtataa tcctatggaa ttgaatatca
     2341 tagcaatgta tttgaaaagc aaattggaaa acaaataggt gcaacaccat aaatatgaaa
     2401 aaattgggaa aaagtagaat ggaaatttgc ttacgtctca cgagatagct cacactatta
     2461 atctgaagaa caatgaagtc gacttttaga aattgctaga agaaagtaaa gcgaattatc
     2521 actagttact atagagtaag ttcaaataaa gcatctccaa cttacatggt tacatgagga
     2581 tatcaaatcg aaattactca agcttcctat ggctagagtc gcgagaagtt gttgggcagt
     2641 agacataggt tatattgttc ttagctacac gatcattaga aaggaaatcc tattatgtat
     2701 agttatcaag aagatgcaaa agtccaaaaa aatcgctggt ggattttgat tgctatatct
     2761 atgtttacct tcatgtccac attggatggc agtattgtca atattgcact acctaccatc
     2821 tcagatgata tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt ttatctgatg
     2881 attgtctgtt cttgtttgtt gctgtttggt aaaattggcg atagccgtgg gaaaatcaaa
     2941 gtatttcgga ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg gttcaatcat
     3001 tcgctaggta ttttattgtt cgcacgggtg gtacaagcca ttggtgctag tatgactatg
     3061 gctacaaatg ccggaatcat cacggaagtc tttcccatac atgaacgtgg tcgggcattg
     3121 ggagcaatag gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct tggcggcttg
     3181 attttgtccc aattttcttg ggcgtacatt ttttggatca atgtaccggt gggaatcgta
     3241 acgatgttga ttgctgaaaa attcttacca aaagatatca ccatgagcgg ccatacaatc
     3301 gatggagggg gctttgctgc cattgcggct acgattatca gcttttttgg agcaatcttt
     3361 ttggggcaag aaagtggctt tttccatcca gtcccccttg tactgttcgt aatttcagtg
     3421 attgcctttg tcagcttttt aaaagttgaa aagaaagcag cctctccatt gatttctttc
     3481 ggtattttta agaacaagat ttttaccatg agcttgatta cagccttgtt gattttttct
     3541 tccaacttct ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg cgggttgagt
     3601 cctagctatg ctgggctgtt gatgatggtc tttcctttga tgatggtcgt cggggcgcct
     3661 ttaagcggct acctgaccga ccgggttggc ccggagattt tggtattagt aggcttgggc
     3721 ttattgtcgg taacccaggt catgtatatg tttttgtcag tggactctcc tttgtggcta
     3781 tacattgtcg ctactgccat catgggtgcc ggcaatgcct tgttccagtc ccccaataat
     3841 acgatggtta tgagctcggt cactatcgaa aacttgggac tggcaggctc gatgaattcc
     3901 tttgcccgaa atttggggat ggtcagcggg atttcgcttt ctacgacggt cttatatcaa
     3961 gcgatgtctg ctaagatggg ccagcaagta actaactata tcgcaaatcg gccggatgtc
     4021 tttttatatg gaatgaagat taccttttta ggcagctttg ttttgtgttt tgttgccttt
     4081 ttcctgacta tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt ctgaaaaaac
     4141 cactgttgaa gaatttttgg aggcctgcgt atgggtgagt gggatttcca tggatgatgg
     4201 aagatgaagt gaacttctaa aagccgaaaa actcaagtat tatcttcaaa atactagtgc
     4261 tcaatgagat gcttgatttg atcacaagaa gactgcgaaa gccgctggca accgcaagct
     4321 aggtatccca ccgatggact acgttttaga ggctactggt tatgaatacg gagccaacgc
     4381 tctcatctgc ataagaatac atcacccaga ttatgtaaag attttcgata cttctgtcaa
     4441 aaaatcatta agatagataa atgatttccg tctagtcaaa ttggttcaga atgtagacac
     4501 acagatggta agaagtcact cacaattcga gaatggactt gtcctatttg ccgtatacat
     4561 cataatcgaa acgtcaacga tagtatcaat attttgacca agggctatga atacaagcat
     4621 tgccttagaa aacatcaaga accttaggaa caacggggat agcttggtta ataagagata
     4681 ccgctgttta ggcttgcaag tatactcttt tatcaagaat tccgtggctt tagtcatgag
     4741 aggcttaata ctatgaaaat tttctttagc atttttgatt taggttcctt ttctaattat
     4801 aataagatga ccactacagt aacctactga aatatataaa cagccactgt agtaccattt
     4861 tcaaagtagt ctatgagagg agaatcttca ttcttatgaa cgctggaatt gcggatatga
     4921 atttaataaa aaaaaccctt aatgatttta cttccaattc aatatcaaaa ggtactggta
     4981 tcaatttaag cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa aagctgaatc
     5041 ttttagatgc tataaaaata acggaatttg ctatgaaaaa tggaaaagct gagattgaaa
     5101 tatggagata attatcgtct agtgaattac ttgccactta gctgaattta acgatccttg
     5161 gtgcttgaag ggggagattc ttgggaatag agcatacttg caagcctatg tctttactaa
     5221 caacgatatc tcttattaac caagctatcc ccgtagttct aaggctttta cttttatcta
     5281 agcaataatc gtattcaaag gaaatttttg acccttagaa agtctcattt tatcagacgt
     5341 gagcttaggc attgctgaat tttgttaatt cggttttagg ttgtgctttg agcataatat
     5401 gaaagtattc tttatcacga tttcattcat ctaaggtaat gtgatgtgat tctgaaattc
     5461 tttcaaaggc agtttttgca taagctgaca ttacatcatc aatgacatgt ttacaatgtt
     5521 tcactactaa aataaggggg taaccaagaa gaaaaactga atgattattt gtatctaatt
     5581 ccatggtata tcaaccattt cctatataga ctgattatga catggattaa aataaaaagg
     5641 cactatgtct taattgtcgg ttttcgagtt accgaatggc attcatcacc cacctataga
     5701 ggatgggcga cttctgcctg aaataagtta cactacttat aacttctaat aaaattagat
     5761 tgagtcatta ttatttaaca tcaacgattt tccagtttcc atttttttgt aatactaatt
     5821 tgtactgaaa gtagctagtg gtttttgata cattatcaag gtattttatc tttgtactca
     5881 ctagaaaatt ttttccgttt tgtagataaa ctggattctc taactccgaa aactttaagt
     5941 caatattgat tggtcgcatc gcaccatttt caacataata ctccaattct ttttcagaag
     6001 ctgatggata aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc gttgttttgg
     6061 catcaatttc tgaatcgttt tctacttgtt ttgcttcata ttttgccttg tctggctttc
     6121 caatcattgt tggcaaacta gttactaaat gattcctgtt ttcatcttca aagattgtca
     6181 ctcgatatgc agaagaaatt gattgcgtct tttttccctc tgtaatatgt tgctccacta
     6241 aaaatgaaac gacaaattct tccgagtgtt tttcaacatc tagaattttt acagattgaa
     6301 cttcggaact cgtgggaata tctgctcgaa ccatatcttg gattaaagcg agaccgtttt
     6361 ctgtaaggta ctgttcgaga ttactcattc tcttttcaat tgcttctttg ttatttttcc
     6421 atgaaaaata ttctttcgca aaatcctctg taaaactttc aacgccagaa gtattcacta
     6481 ccttctcttt tataaccact ttttcatgag ttgtatgttg atcaatggcg gtgaaatttt
     6541 tataaacgcc aaaagcaaga ctacaagaca ataaaagcca aagggcaagc accatttttc
     6601 gatgcttacc cacggataca actcgttctt ttttcttttt tgggctcttt tccttttgat
     6661 tccgttcaat ttttatcttc attctttttc ctcttttctc ttatttgtat cggccagctc
     6721 cgataagatg ctgccgccaa tagttttccg ttagattcgt ccaccccact ggatctcctg
     6781 catgaaacat gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa gtaccggcat
     6841 cataggttga atgaaagaaa actaaatcac ctggtttggc atcttttaga tcaatatgag
     6901 tcatggcatc atattgatcc tgagccaccc gaggaagttt caggtcaact ttggcataac
     6961 accattgggt caagccacta caatcaaacc ccgtttctgg acttgagcca ccaaacacat
     7021 aggccgttcc ttcatactta aatgcctcat caaaaatttc ttggactatt ttgtcatcaa
     7081 actgagttgt agttaggtat tgcttcacta ataaacagta aaacatattg ccataattat
     7141 accgccaccc accattttcc ttaatcgcga ttgggttggg gtaatcgact ttttgaccac
     7201 ctgatttttc ctttgaaaaa gattcagcta aagcaaaact atgcttcttc ccgtttttcc
     7261 cgacatgatc tagatacccg ccaccatagt tataggcctg aataatacta tcttgatcac
     7321 accctagttc tttggaacgc ttaaccaaag acgcaaaata gagacagcct tgtttgatgg
     7381 atgcctcggt acttaatgaa ttaggtggta atccggctga ctcagaactt tgcataacgt
     7441 cttccattgt gccaccagat tccacttgaa taatcgccaa aagaattgga atatactctg
     7501 ttatatccga ttctttggca tacttttcca ccattgcacg gtgtttcaat acttcttctg
     7561 agacactagt tccgccagga gaagtgccag aactaccatt tccctcactg tcttcaccaa
     7621 acaacaaacc cacacacatc aaaataccca taaaagagat ggtcagaaaa gttaatgaaa
     7681 taacacccac tttcttcaag ttcatttttt ctcacctgac cttgattttg gacgatggtt
     7741 cattcttttt tgtacttttt gattggtctg ctttggcaga gtggacctct gtttcacttg
     7801 ttggaaagaa tttttcttac ttgctgattg gcttttccct tttgaaatga tttcttgact
     7861 agttagtttt cgtttgattt cgggattcag atttgctctc acaatccgct ttggtgcttc
     7921 ttttttcagc atcatatctt tctgaggttg agctgcttta tctattggaa tattcgccct
     7981 tctttttccc tgacgatttg ttgcttcact cagtatcttg cgtttttcgt ccattttcgc
     8041 atttcttcgt tgtcgttgtt tttctcgcaa atccactcga tccgcttttt cttggaacag
     8101 tccgcgcttg aattcttctg gtgctttttt cgacttttcg attcctttat ggagattgta
     8161 tttcaaattc gttggcgtat tccttacctg atcctttact tgtttagtct tatctttcac
     8221 caaagcttgg gtatccaaaa ctttgccgat ttttctccca gccaaattca ttcgggattg
     8281 tttcttatta tttgaaactg gattctcctt agttaagtca gatagtattt cgtgatcgtt
     8341 cggtaatcgt gaattctttc gtagagaaga accggatggc ttaaatttgg attttgattg
     8401 ttcctttgcc aacttatttc cgactgctgc accaccacca aaagccaaag ctcgtcccac
     8461 atttcgattg agttgccgca attttcgatt cattaacatt tgcggttttc gcatgacgcg
     8521 tcttcccatt gactggctat cattactctg gaggttgaac atactcataa tgtcgcccaa
     8581 tttgaaatag ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga aaaatggata
     8641 ggttgccgaa atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa tcaccaaagt
     8701 aacacccgct cgcatcataa tcgtattgaa taaacgaata atcgccttct ttcctaaact
     8761 ttcataagtc ggcaacatgg acaataagaa actaattggc agaaacatcg caaagataat
     8821 gaagagaatt tgcgagaaca acataatccc tgttagaaga aaaacaaaga aggaaatgcc
     8881 aatattgaac aataccaaaa agaccacggt ccctaaacgg ttcatggtct tggtaatact
     8941 gagattcgca ttgtcattgt cttcaatctc tgccttgacc gcttcttccc gatctttgcc
     9001 tttgttttca tctggactca cagatagaat cttgttgacc cggtcttcac caatttcttc
     9061 tatgttggaa tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa tcgaaaacaa
     9121 actatcccga atcaaatcca cactatcttt tccttggctt tctgaattgg gtacaacgat
     9181 ctcggttcca agggtaaggg ccgcttcact aacatctgag ctaaagtcat tgatttttgt
     9241 gatataggta ggcgcataag caatgaacga acccgatagt agaaaaatca tcacaaaatt
     9301 aatcacggct cgaactgctt tcgtggtttc tcgttttaat aatccggtat acgccacata
     9361 cacccccaga gctaaaatca tcaataatag aaacccaaaa taaaatccgg aggtctggag
     9421 tccattttca gtaataccag ccaatgtttg gatattcttt ccaatacttt cagccgtatc
     9481 cgaaatgaaa tctaatttgt aagcctcttg aaccacataa cccgtggcgt tcgacaaata
     9541 caaactcacc gtccaaatga aattagtaat ggcataaaga ccatacatca cgcttttccc
     9601 taagccatca ccccaattcc aaggcaacca atcccaagag ctatccacaa agaaatctag
     9661 ttgatagttg ttcagtgaat atttggaata tagatttcct gcttcaactg tatcatcaac
     9721 tagccctgtc gcctcggcta ccgtaccaac taaactcaat agaactatca gagtgagtat
     9781 gctaataaaa acgattccca caatccgaaa aagtttcttt ttcatcccct cactccattc
     9841 tctcttgaac aggtggacgg gtatcaaagg catggaagag ttcttcaaag actggatgta
     9901 cctgaaccac gcctacccga ccatacaaat cctgcatcaa gcattggcca ttttccaaat
     9961 ctcgtaggcg tttttgattg ctttcatctt ctcgatccaa gccaaagaat tccaaggttt
    10021 tcttgatttc atgaatatcg gtactgcgaa acgcaaactt caacccgata ttattcttca
    10081 agcgttcatc cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg gcattcatag
    10141 cccgcccagc acgaacgagc ttattcgata atgttttccc ttgcgctact tgaagaaaac
    10201 tccacgcctc atctaagtct acaattttga agatttctcg attactatgg ataaagtcca
    10261 aggcaaaagt ggaaatgacg attagcatgg aaacactaag caattccatg gtggtatatt
    10321 cttcaaaagt ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg atatttaact
    10381 gcctatctaa actaatcgac tgggtaatcg aaccatctga gaaaagcaaa tgggcaaaat
    10441 cataatcggt aaaggactcg atgtgatccg cgatattttc cgcaactggt gagccttctt
    10501 ttcgaagctc attaattact tgtaataatc cccgttgatt gctttgggta accgtccgaa
    10561 tggccttacg caacactgga aacttctccc catctcgact agaaattcct gttaaaaagg
    10621 tcagaatatc aattgctaga ctttcagaat ccttcttttt ctccataatc acataaggat
    10681 caagtaatcc ttgatttttt ggcttactag ttaagttgag aatattgatt tcatccgcaa
    10741 tttctggcaa ggtttctttc cagccacccc gttccccttt tggatcgaca atcacagctt
    10801 gtccaccaaa aaggacggcg taataaacta agagattgtt actaaaggac tttccgccac
    10861 cgagtgaacc gaggaatgcc gctgctagcg cattggtaac tgaatccttg accccttgtg
    10921 aggccaatgc cggtttcagg taaacattgc gccccgtatc tacgttataa ccaaagtaaa
    10981 tgccttccaa ctcccctaac atctgagtgg cgccaaaacc aagtccggcg agaaaatcag
    11041 acgtaacata ctggatataa tcattcatgt atcgcttact agaaggtaag aattcttcat
    11101 gtagccccat catatcgcca aaaggccgga ctagttttac attggtatca tcataaaaat
    11161 ctagcacttc atcacaccgg cgctttagtt catctactga ttcggcactt actcgaacca
    11221 catagctcag tttgtacatg gattctttgg actgatccaa ggtagtttcc aattcatcta
    11281 cggaatccaa tgcatctaag acattggaat ttgtttcatt gtcagattga taggcatggt
    11341 tgtccaagtc ttttaattcc tttttcttat tgcgaacggt agcaagtgcc tttttgttcg
    11401 tcacaatctc cacattcata ctagtgtcaa ttgggaatgt aaattgttgt tgctggtaat
    11461 agaaaagttc tgaggaggga aactccattt cccccacaat tgtattaatt gttaagtacg
    11521 ctacatatga ttcatgattc tcatgttcca tgcataagta ccggggcttt tcttcaatca
    11581 aacaacgact gggacgtaat aagtcgtaac gtttcaccaa agtttccgac ttcagctttt
    11641 tctttggtag ctgaaattca tattcttcaa atggtgtacc cttttcgcca tagatatgtt
    11701 caatcaaata catcagatca ctcggtgtga ctcgtctgac tttaaatctt cgagccaatt
    11761 tactttccat tagtttttca agcttggtat atcggcgaat ttcttcattg gataaggaaa
    11821 caaaatcgcc catcaaatga tgattcactc catagacaaa ttcttgaaag ccggagaaga
    11881 aagatttctt gagattcttt agattgacct cttcatctgt cgcaatcagt ttgaagccaa
    11941 taaaaaagcg ataatcaatc tgactatcgc caatcatgga tactaatgcc tctgtctgta
    12001 aatcaattcg ttgtttcgct acttctgtta atcgcccggt aatttccttt tttgatcgtt
    12061 cttgcgtggc acgaatacta ctttctgtgg caatttgtaa ggcatgaatc ttgccttcac
    12121 gattttgcgc aatcaattga cgaaagttat cgtggacttg atatttctgt tcaggtgaca
    12181 aaaaggagta attgtaaggt attaactcat agtaggcaaa acattctccc tcttgattaa
    12241 agacaagatt attttcaata tacttaatcg ggtacatagt tcacactcct taccagagta
    12301 atgggttcgt cccatcgttt cttctgttct ttgactttct ttcctgcgaa agtgacctta
    12361 aatcgtaagt gatagctaat aaaagatcgt aaaaatccca atggtttctt accgtcaaac
    12421 gttttttgcg acatgaacca agtaactgcc accggtatac ctaagtattt taaaaaggcc
    12481 ccctctatca tagatagtgg aggcacatgg gcaaatacga tgacaaacag caaggataaa
    12541 acaaaccaag ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc attaattgca
    12601 taaatgacct tttcaactgc ccaaatactg gtgtagcttt ttattttctt catcaaatca
    12661 ttcctttaaa aagaaggata gtttagaaat caactaccct tcaataattt tgttaatatg
    12721 gatactcaaa aacacctcga ctcgttacca aataattgcc tccaatctcc aagtctctac
    12781 cacacgcatc aaaatcaata tacgtcttca agtgttctgg tacttctcca aaatcaccag
    12841 cttctacaat caagaaatat gctacatcac tcatatcatc gcaatctgga taatagataa
    12901 tatcatccac atgctctacc atctcctcaa aagaattgaa gaaagcatgt tgaatctcag
    12961 aagcaacttc accaactggc gttccttcaa gttcctccgc taagccacac aaccgattaa
    13021 tttcctcaat tggcgtatac tcatcaatct caaagggaag ttcataatca tgaattgcat
    13081 attcctcgta ttcgtcattt aacccaattc gttctttcac ttcatcaaaa tcgacaggtg
    13141 gggtaaacca cgcccccacc aattcacctt cgttatattt cccgaggttc gcaatataaa
    13201 cacgcatctg ttccatcgtg cttccccctt acgcaccgac aattcggtta aacaaactga
    13261 gtaagacatc cttcacccca gaagcattaa agaccaatcc gaccgcaatc aaagcaatca
    13321 ccaaaaagcc aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa ccaatgacca
    13381 caattgccag taagactaag gattgggcat tggttaaaaa ccattgatat atggataggt
    13441 aagttcctga tattataaat atctcaaact tttcccccca ttcacacgga gcgtgcgact
    13501 ttcaccgcac tccgcgttcc atcgtgttta tattgaaaag tatttatgta gtagacctat
    13561 atcaagttta attcttgatt gccagctaat actctatatt tatttagtct tatgagctgg
    13621 actttattta gcttcaatag agctatatat ttttgtattg tttcttctgt tttagcgtgt
    13681 attagacggt gtaccgcctc ttttaccaaa ataagatttt tataatcgtc atttccacca
    13741 gctccagttg gtacaatatg atgacaatgt atttcattag cttgttgaaa ttcttccaga
    13801 gttatagcac attttccatg ttgagcagaa aatagcgaaa ttcgattgtc tgcgtattct
    13861 attgtgcgat tttccaaaga taatttcatt aactggtaca tcagtaattt atcaacactt
    13921 agattggtgt ggataaattt tcttccctct agagtgtagc aattcgctaa atacaccttt
    13981 gccattggtt ttctgtgttg gatatatcca acagggaaaa taggttcgcc ctcgccagca
    14041 acataccgaa gcattttaga tttaccatat cttgttgcct cctttgtcgt aagttgtctg
    14101 cctgtttttc tcaatctgcc ccttttgttt gtacctaatc tgttagtgaa gatagccatt
    14161 acagctctat tcagtttcat acaatccaga tttacattcg ttgcaatctg ataataattt
    14221 tgcataccta ataccattga attataaagt cttgtttctt ctaattccgt tttccctttt
    14281 gagggagaag caattttctt tgcctgtgat accagcttgt ctttttggtt tttgaattgt
    14341 ttatcactta tatgtgattt aacaactaac ttctttcttc tcggtatcat tttaatcttg
    14401 aaaccaagaa agtcggagta tctttttcta acatttacaa ttcttgtttt ttcttgtgat
    14461 acttccaatt ttaatcgttg ttcaatccat tgagtgattg ctattttggc tttttcagca
    14521 ctttccttgt agcggcagaa aactctaaaa tcatctgcat aacgaaccat atacatttcc
    14581 tttaactttg ttttcttcat ttctttgtaa gcgttgcttt tacatgggct accgctttta
    14641 ttgatatgaa ccacatagtt ttttgtaaca ggattttcct gccattggct ttctacccaa
    14701 tggtctaact cattaagaac aatgtttgct agtagtgggg atattattcc cccttgcgga
    14761 gttcctttct ctggatatgt tattgtaccg ttagtcattt tgattggagc ttttaatatc
    14821 ctttttaaaa tgaatatcaa gtgcttgtcc cgtattccca tagcccatat ctgttttatc
    14881 agcttggaat ggttcacgtt gtcaaagaaa cccttaatat caaattcaat cacataatgt
    14941 agctggctga tttgtaggcg gttataggtt gcttttattg cattttcaac tgacctatta
    15001 ggtctaaaac catagctgtt ttcactaaat ttagcttcgc agattggttc taatacttgt
    15061 tttatacatt gttgtataag cctgtcccac atacaaggaa tacctagagg tctggtttta
    15121 ccatttggtt ttggtatttc ttttcgcctc actggcttag gtcgataccc atgtggactg
    15181 cctgcaacaa tgtatcttac ttttttgaca actgtttctg ctggcaattt gccaatatct
    15241 ttaattattg taccgtctgt tcctgctgtt ttactgcctg catttgcttt gatatttcga
    15301 tatgccagta atatattttc tctcgatagg ataatatcca taagatgagt gaaaatatct
    15361 ccattcttac ttttggcata taaatcatca aaggtgtttt gcatttcgta atattcagcg
    15421 tgtcttaaat cttctacaca caatgtttca tttttatttt taggcataag gcttcactcc
    15481 tttacttgaa attgagtgag cttttttatc ttactcgtaa tccttattga aacaacataa
    15541 tacttttcta atatatacac gacttgaggg cattcctcca ttctcattac aagaatttct
    15601 taggttcgcc ctctgctttt cagcattagt tcaactgctt attgttcttc gtcagtttat
    15661 tctcttgatg agaacccaat acctttcctc gttccgataa tcttatctat acatatatat
    15721 ccttaggtca ctagctataa gcctgctggc ttgataccgc ctgtaacgtt atatggcatt
    15781 tcataaccta tattcttact ttgccacacc agctacgatt tctcgtacct ttgcatttct
    15841 acaaagttca aatttagacc cgtacattcg ctgtttcgtc agttccttat agaacattct
    15901 aaccatagat attttataga cccccgacct gttggatacg ctacccacct ctggatagtt
    15961 ttcgatagaa gatatatgtt catcaactat tacggtatct ttcagccgtc tttaccgagc
    16021 ttcaaacatt ctgagtttcc tcatacaatg cttgtcggag gctcagggca ggcgtttcag
    16081 agcgttactt catcattcca cctgtcagat tatcagttct cctaataacc aaactttttc
    16141 gttcttttat tagtgcctta gcttttcact aaggaacgag tcgcacataa attttgtccg
    16201 aaattcatct tgtcactttc ctttcttttc cattgctcga tccgctgctg cacttgcatt
    16261 catcaagcac atcacagtaa caccaagcat actgccacca aataccaaaa aaatatcttt
    16321 tacaattccc atgacgattc ctcttttcat ataatcaaat tttcaattgc catactttgt
    16381 tgctccaaaa tctttttatg tcggtctgat aagcgtgcat tctgtaccat atcctggata
    16441 taggttgtcc gattcaatcg atccaactcc ttagccattt tccacgtagg ggcgacttgt
    16501 cggcctagcc aattcaaggt tcgttcaatg gtatacggtt ttggctcgga agttaattga
    16561 atctctttcc gattccgtcc aataaaacgc ccccattgtt cattcaaggg ccagttggtt
    16621 cgccttttac cttctacttt atccgcaaat cgcaagtaac gattgataat ggaaaacgtg
    16681 gtgctctcaa tgctacgacc ttttaacaaa tcttgaatcg catgaaaagc acggtcattt
    16741 ttcagtcgaa tctcaaaacg atttttcgtc tcagtttggt ctaatggaat ccctaacttg
    16801 atatattgtt catagtcttt ttcatacaaa cagaaataaa cctcactctt gagactgccg
    16861 atatataagg tattgcccat gccgtccttt tcatcagcct ttaaaagttc cccggaacga
    16921 taacttttaa aggtacgaaa caaggagata cattcttcct tctgacattt tttcgttagc
    16981 tcaggtatat ccaatagccc cactcgatca ttgattgcca agtccaagcg tttcatcacg
    17041 ccaccggcct ttagacaatc ctcgaaaaag tcgtaccagc tacgcttttg agcgagtaaa
    17101 aaagtttcaa attgtcggca acctcgcccc tttaattcta aaagcacacc tttatcttct
    17161 tcatgagaca acatcaccac aatatcaccc atgacatact gttcttgata ggagtaaaag
    17221 gcataatctt catggagcat atactcaaat ttcaaatgga gaatttcttg aataattttt
    17281 cgtgcatccg ttgtgggaaa gcgaatcctt acatagtcaa acagtaacgt caaaggcaaa
    17341 tcgggattaa agctttccag ttggtcaaaa attttcctca tggtttttat agatgcggtt
    17401 acgccaccat tttctatctg atttaagtac ggccgactaa gtccacaagc cgtagccaat
    17461 ttattttgtg aaacgccgta ttcgttgcgt cggtctttta atagccgata atctaaattc
    17521 cgttgtgcca agttctcacc tccaaattca aggtgttaac tttttcaaat gagttaacac
    17581 ctatacaaat tacttactat ctttgataca acaagcattc ttaatggttg cttacttatt
    17641 ttttgtgttt ttgtaccccc ctgttagata cgggggtgag acatcatggt cggctaacgc
    17701 cgtccatgaa caggcacagc accacggagg atttctgctt cgcgaatcct ccgcggtcag
    17761 cgcctaacag tcagttgtgt tggtttaggt tactcatctg taataccatt tacttccaac
    17821 tctgctttca tttctaacaa gtattgacga atatctggtt cttttgcttg gtccgcaatc
    17881 cgctcaaatt ctgcaattac ttgatttatt tcaattcgag catccgtctc ctcattcatt
    17941 aaatatggat cgccagcgac tttgacacca ttcttgcgaa tatcaaattt taaccgtcgc
    18001 aattgttctt ctaattctgg gtctgactga atctttccaa tcacccaata aatttctcca
    18061 atcaactcat cataaaccat gtacatccaa ctcttttaat cttctggcaa tatcaaaaat
    18121 gaccggaact gttacagagt ttccggcttg cttatacaac tgactatctg aattgacttg
    18181 agaatctcga tcaaaagccc aatcgggaaa gccctgaagt cgccaacact ctctaggtgt
    18241 tagcttccga atttgatact gatccgtgac gatcgcttgt tggtctcctg ttagtaaggt
    18301 atgaacactc tgttttccca gacgacctcg gcgacttgtg gaattaggaa aagccagatt
    18361 cacactgtct tctggcttca cctcttgata ttctgtttca ttttttcgaa tcatgatttt
    18421 tgtaccacct tgtttcgttg acaaggtggg ggcggttcca gtaacttcat aaactcgatt
    18481 accttgttca aactttcccg gtaatagtcc tgctacagag attccatccc ttgctggcag
    18541 tgcgattttg attccttcat cacctgttaa ggttggcgct acgccatctg aaccatagac
    18601 ttgtccaccc attcctcgat tggaaggatt gatatttacc aaatttctga tgttttgatc
    18661 agatgttgaa gacggtccaa tgataggaaa tacttgttcg gtacatgcgt ctcgagaatg
    18721 tccgataagg aatatccgct cccggctttg gggaatgtag gcctttgagt taagcaccta
    18781 ccactccacg tcatacccca atccatccag cgttcggagg atcgtctcga acgtagcccc
    18841 tccttcgtga ttgagcaatc ctcggacgtt ctcaaggaat aaaagcttag gtcggagaag
    18901 agtggtgaac cgagcgattt caaagaataa agtacctcga gtatcggaaa atctttgccg
    18961 ctttcccgca attgaaaaag cttggcacgg aaatccgccg caaaggatgt ccactggtcc
    19021 gagggattga ataaactcat ctgatacact tgtgatgtca tgcatttcca cctccttact
    19081 tgtatcatga attgctttat aactacgtct agcaaattta tcaatttcac aaaaaccgat
    19141 acaatgatgg ctcgcctgtt ccatacctaa acgaaagcca ccaataccgg cgaataaatc
    19201 taaaaatctc atacattacc tcattcattg caaagaaaaa agccaagaac attttgctct
    19261 tggctcatac attattaatt tgtcctacta ttttttattt aatccaacta atttccgttg
    19321 tttttcattg gcctgatcgg ctacatattt aatcaccgtt ttgaactctt ttgcagtagc
    19381 attttccgat aaatccgcaa tgctcttatt gtatttcttt acaattttcg ttacttgttc
    19441 tttctcagtc atgtaattga acctccaaat ctttcctact ataccctagt ggtaaaaata
    19501 attctagatt atccgtagca taatgaactt cggaaatatt attcgtataa tcttttatta
    19561 tgatatgaag caatacatct ggatgtttac tctttacttt tgcaatgttc tctcttgatt
    19621 tgaaaaaagc gttaataaat gcctttttcg gcacatgacg tccctctgca atttcacgtt
    19681 cttgtgtaaa tttccaagcg attttagggt cttgataaac atagaaaatc gtcactcgaa
    19741 aatgtttttt caacgcccgc gagatatttt tttcagcact taatattgca aaagttgcat
    19801 ccagaataaa agaatagcca tgatctaaga catatctaaa tgcctgctct accaaccaag
    19861 aagatgcttt ttgaaagaga ctagagtttt ttccattata atcaggaaac tgggtgcgaa
    19921 agtaatccgc atcaataatc acatggttat cataattctc agctaatcca atggcaacct
    19981 ctgattttcc agccccagga ctccctgcca taaaaactgc gtctcgtcca acttcggggg
    20041 atttcccttt gataatataa gaaataaact tatccttatt tgcttttgca tactctaaat
    20101 aagaatcatt actttccata ttaattatcc cctttcttcc tactatataa aagtattata
    20161 cgttacttga agtataaagt cagtattgaa gatcactcaa tcattcatct tttctaattt
    20221 actaattgaa tctaagaaat catacccttt tggtacaagt ggcgtataaa actcactaat
    20281 cacactgcca cctgtatcca cataacctcg acctttgatg tgcttcataa agaagttttt
    20341 ttcgacctcc ccaaacatca tggaatatcc gagttcactc atacgaccca aagccacgcg
    20401 aaagttgaat tgatcgcgga ttccgtctcc taaatatttc gcatccggcc tttggcaagc
    20461 caaaatcaga aagaaaccag attgacgacc caacatcacg atttgtttga gcttattcaa
    20521 aatcaccgca ctttctttcg tcgttaacat ctccatataa gccacgtatt catcaaagat
    20581 taaaaagttg ggtggaagtc caagataggc ataattctct cctgttttgt agttagacat
    20641 ttctttcatt gccttgctac gagccatcat acgttcatag aaatcttcca cacaagcaga
    20701 aatttcttcc ttttgtgaat aaacatgagg catcaccgta cctaaatcag ctaaatctgc
    20761 atttttggga tcgaggataa acaattctgc atctgacttc aatagtgctt cgataatggt
    20821 gaggaggaaa taggtcttcc ctccacccgt gccaccagcg attaacatat ggggtaaaga
    20881 atcataagcc catacttgat ttttcatcaa tcgcagagtc ccattttctg ccactacttc
    20941 gtctatccca attcgattgg cgatcatatc atacagtaaa gtatactcca cataggagtc
    21001 tttgagttcc ttttctacta actcacaata cagtccgctt tctaacttct tttccaattt
    21061 taaaagctga tcttggtatt tcccaagtga aatttgaacg cgaatagaca gtaatccatc
    21121 tttcattcga taacagattt tggggaagta actgatagtc tctctggttc ggctactatt
    21181 caaatctttg aaaaagcctt cactttgagt ttgtttcact tcataccaat ggttctctag
    21241 aatcatccga gctagctttt gtcgatgcca caagcttcgc caatgatcaa gaaaaaagtg
    21301 aatataaagc aatatcatag ctcctgaaaa agcgagactt ccaagcagac atactaaatc
    21361 ttttatagac caaacgattt caatagtaga aagtgatagc ttagaaatat caaattgtct
    21421 aaactcttga aaataaaaga cgctcatcca accgatgaac agagcgagta gccagccaag
    21481 aacaaagtga taaaccaagt gctgatctcc tgcgcgtatg cgatgtcctt tgtacatttt
    21541 gatggtttcc acctccaatc gaaaaagccc aataggattt cattaggcaa tttcaaaaag
    21601 ttatgctagt catttactgc tacgaggagg ggagttgttt cgtttcaacc aattgattta
    21661 aaaagccttc aatagcatcc ggcatctcca caccaatttc ttccaaaatg gattctgcct
    21721 gccgacataa gttttcattt acttcgacaa ctataaagaa agactcttct tctcctaacc
    21781 agtctagtac atcagagtct tcttcactgt cgctattttc tccaagtaaa ccttgatgta
    21841 taatcagaaa cattttttca tcagaggtta atgctttaac gagttgttcc tcagtcagct
    21901 cgccttttcc atattgatcg agacaatcta aaatatgttc aacattaatt tccataatct
    21961 tcacctattt ctttctttca ttttggttcg taggatttcc ttgattcggc tgccgcttca
    22021 agactaaatc atccgcctta atgaaccaat taacggtagt tccttctcga aaaacataat
    22081 tggcaacggt atccacgatt ggattgacca actctacctc tgcatcataa gcaaactcgc
    22141 gtaagggtac attagctggg atactaactt gaatcattcg cccttgtgca gaggatttta
    22201 aattataggt tcgttctttt acctcattac caattgttcc atcctcattt tgcttccgta
    22261 cttctcggcg taatgcggaa aaacgcaact tcccaaatgt taaacctgaa tctacgacaa
    22321 taccttctgt taatctcatc ttcttttcct cctatgcttt cactaaatca tcaacataca
    22381 acacgtaatc agtaaaccca cgattctcaa tctcatagcc tttggcaacc aaatggggat
    22441 tcacggcttt tagcggttgg tcttgatcaa aatccttttc accggcttcc gcagctacta
    22501 ccacctcaat atcatcggcc cgttgcttac tggaatacaa atgataactg cgaccaatca
    22561 ccgtagtatt ccgtccatat ccttctgtta taatttctcc ttcaccggca taacttaact
    22621 ttccaaaggt ttcagccata tctggcacga caaatttcaa ttccatcttc ttttcctctt
    22681 ttcattgtta gttttggata caaaaatagc gcgactactt ttttaggagg cggtcgcgca
    22741 cgttggttct taggatttac ttgtatcatc tcatcacctt agttccggcg attccagaaa
    22801 taatagcccg ccgtcgcaaa aatcaaagta aaaccaatga acagtaaaac attggaattt
    22861 ttctccccgg tttgagggaa ggtcttcact gtgggactag attcttgaga gccacttgga
    22921 acagttggtg tttccggttg tttcggcgta cttagtatgg ttggaacttc ttttggtgtt
    22981 aaggtttgag atttttcttt caaatcttca ttgtgttttc cattgatatt cccatcttta
    23041 tcgtaattga tttccgcaaa agtaaacttg gttccttctg gatattttcc ggtatctact
    23101 tttttcgcaa gcacagtttt ggtgaattct ttatcattta cttcataatc aatcttgcca
    23161 gatttccaaa tttctttgtt tgtaccatcc ggtaataaag catacagaat tgtttcgaaa
    23221 gcttcttttg agccatccag tacatcatga gtaatcgaca catcatcaaa catatccacc
    23281 acatcaccat gagtaaaggt ctgagaaccg ttttctaggt gggcctttgt ttggatagaa
    23341 acatggtgtt ccactgtaca actgacagtt tgggcttggt tattcaagct aacatccttc
    23401 gctactggct tatcgcctgc ttcaaaagct tccttatttt catacacata gttgaataag
    23461 acaatagttt tatttaaaac ttgttcggcg gttaatttat gctgaatttt ccaagttcct
    23521 gttttctctt tgttcgccaa cgttgcgctt gtttctgcaa tcaccactgg tttggctttt
    23581 tcatcttttt cttgggcagc ttttgtcgca tccacatcaa tggcttgcgc taccacatac
    23641 cagtcttctt tgatttcatg tagattgtaa ctcaatttat caactagctc ggtagaatcc
    23701 agagaagtta attctttgtt tccgtctttc caagtcgcaa gagaagttaa actatcttct
    23761 tcctcaggca aatcatagag cattaaacgg ttcaaactaa cagaaaatgc tttgttcgtc
    23821 agcttctcgt aaggaacggt caccgtttta attggttgtt tttggtcttg ttcggtaatg
    23881 gtaaagacat actcactctt cacaaagtct tctttgtttt ccttaaaagt agaacggatt
    23941 tctaatggcg taatcttttg aaaaccttct ggggcttcta cttcttcaag taaataatcc
    24001 ccataaggaa gattttcaaa cttgccataa ccatcaaacc ctaattgctc gttataagct
    24061 gtggtcgctt catcttcggc acctgtgatt tcattggtcc cttccaatgg cgacacttta
    24121 aaggtcagat cattgaagcc agtttcggta gtgcccgcag ctgatccagc aaatttaaag
    24181 aaatcaaagc caaagcgaat cacttgttct tttgccgtaa catttcgggt aatcacggca
    24241 tttttttcgc tatcatccac ctttttgatg gatacaggat actttgtttc atcaaggcta
    24301 tatccttcgg gcgcttttgt ttcttgccaa taatactcgt tgatagctaa atgtttaacg
    24361 gcaacttggt tcttttcgtc taaagtcaaa gtgaccgttt catcagaacc tttcgttccc
    24421 ttcgctaact ctggtttaaa agcctcactc catttaacag cttttccatc cttagcagta
    24481 aacaaggtgt attcagcacc ctcaaagact gccttacctt gtgctttatc cccagtatct
    24541 ttgtcttctt tcgtcaaagt ggtttcgcca gtgacttctt gattttgccc ttttacgtta
    24601 ctggtaacag gggctacggt ttgattggca tacttcaatt cgacttttac aggtttgaac
    24661 gtattcacga acccatgact agctttagtt tcggtcacat aataggttcc caattccaac
    24721 gcattagcaa tctcttttgg tgtttccgca tgaccgtttt catccgtggt catttcttga
    24781 acgatttcac cggttggact gtctttgcga atggcaaacg tattaccagc taaggaataa
    24841 ttgtcattcc aaagatcact ccctgtttca actccgcttt tatccagaat gatttgccct
    24901 ttttcccgtg cgttttttga agtcacgtaa atggtttcgc ctgctttaat ggtggtagtc
    24961 atgggggtgg tatcaatcgt ataaggcgcc ggtactgatt tttcggtaat ggttactttt
    25021 gtaccatgag gaatctcatc caatgtagca atgccttctt tgtcagtagt cacgtctttt
    25081 gcaggtaaag tttttccaaa gtctaaatgg aaaaccgttc ctggtacaac atcacccgat
    25141 tctttatcga cttttttgat ctttaaagaa ccctccgttt ccacatcaat tttgattgtg
    25201 taggtattag gtttatcaat cgccccggcc attaaagtct gttggccagc ctttttatag
    25261 gcgacaggtg ttccggtacc agcagatttc ttaagcgtca gcacaccact ttcttttgaa
    25321 ttggcatttg gggtgattat caactgatta ccattcacac gataatcaat gtttgcggca
    25381 ttttccacaa cctcatcgaa ctctgacaaa ttcagattat tcgtatccgt cacagtagtc
    25441 gattgcccta atactgtttt agccgtacta ttatggaagg ttggtttctt ctgataatcg
    25501 tcaatggctt gatttatttt tgcctcaatg gctgcgatat ttacggcact accatctgat
    25561 cgttttattg agtgaagggt atacccatta acttcttgcc agatcatctt ctgtgccaca
    25621 atatgagtat ctgcatctgt acctactttt ttccataaaa cggaaactaa tttggcttta
    25681 tcggacatat ctggtaacgg gtttttctca tagccaggag tgaactcatt gtaaatcggg
    25741 actcctggtt caatacagaa aatatcttgt ttaaagccgt tgtacactgc ataatgcgga
    25801 acagtgactt ctgacattgg acgaccatca ctaaaagttc cttcaacagc atattgatgt
    25861 gctaaatcta gttctacggt taccgtttgt ggatgggtaa tttcatcagc aaaagtaatc
    25921 gtaggagcaa ttgctccaac aattgcttga acagccaaac tcaaaatagt taatacacat
    25981 aatttctttt tttgtttttt atacatgaaa tgttctcctt tcaaattaag cacaaaaaaa
    26041 taagatgctc gcttgaacat ctttgtttat aaagtctttt taaaattttt attgactgaa
    26101 tagaatggat ttgagaatga atgagcctaa aaatttaatc taaaatacga aatatactgc
    26161 ctttaaatta gaacacattt tagaacacaa acatttcaaa tttaatcaaa tataataaaa
    26221 tatatttacg ggaaaacctt tataaatcaa ggtttttcaa acttattcaa tgatacgaag
    26281 aaaaaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg ttaattgcga
    26341 ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc tgagcgcagt
    26401 taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt ttttgtgttt
    26461 ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta taaacaaacg
    26521 ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt tgtgacagaa
    26581 gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg tttgataaat
    26641 attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa gaagggattg
    26701 tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc aaacggcatg
    26761 tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt ttatatggtc
    26821 tggcttcagc gagaagttcc aacgcatata caaggacgac ttatgtcaac gataacaacg
    26881 attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt tgattggaag
    26941 acaacgcaac cacgtctgcg agacagtcta atttttctgg gagggagtct tgctatagtt
    27001 atccttataa ccggtctggt aaaattactc aagcttgatc tgaaagaagc aaaaattttc
    27061 agtgaagagg aatacagaga aacgactttg gtcgaaaaga aagaatcagg aaactgatac
    27121 aagcgtataa caaactgcct gataatagga aagacacgta ttgtccgatt gttttttttg
    27181 acattcaatt ggaaaattta cactttcttt atacatttct ggctgctttc tttatacccg
    27241 tcaactatac ttcactcatc aataagaaag aaggataagt atggattttg gaaatgaaac
    27301 ggtcttgaaa gcaactggta taaccaaaaa atacggtgct gccaaagcat tagataaagt
    27361 atcaatcgaa atcaaacgtg gaatgatcta tggattgatt ggggaaaatg gagcgggtaa
    27421 gtctaccttt atgagaacta ttatgggttt gatctcgatt gatgaaggtt cgatcgaatt
    27481 atttggaacg acggatttgc aggcagcaag acgacgtatg ggtcaatcga ttgaaacccc
    27541 tgctctttat ccagaattaa ctgcaagaga taacctacgt atccaagcag cgaacggcgg
    27601 tgtgtcggat agagaaatcg aagacctgct gaaaatgatg cgattggaaa atacagggaa
    27661 aaagaaagca aagaatttct ctttaggtat gcgccagcgt ttagctattg caaatgcact
    27721 gatcacgaat ccagaatttt tgattttgga tgaaccgacg aatgggatgg atccagcagg
    27781 gatggcagaa atgcgagaaa tcatccaacg tttggtaaaa gaacggggca tcaccgtctt
    27841 gctttctagc cacttgctag atgaattgtc acagatcgcc actcactatg gtattttgca
    27901 tgaaggacac ttgatcaaag aattatcgaa agaagaattg gcacaagaat ctcgtcaatt
    27961 tataaaaatt gacacttcgg cgacggaaca agcagtaacg gttctcgact ctcttggtta
    28021 tagggattat tttgtacaat ctagccgtgt tatccagctt tttgaaggaa ttgaccaagt
    28081 agcagccatc aatcaagcat tggtagaagc aaaagttcct gtggatggta ttcacctagt
    28141 tgggcaaaaa ctggaagatt atttcttaca attaactgga ggcaatccac atgtttaatc
    28201 tattaactgc tgaaaaaata aaagtatgga agagccgtaa aatgtgggtc tcactaggac
    28261 tgatggtcgt acttccgctt ttttattctt ggaacgaatg gtatatgcat acaaaatacg
    28321 gcaatgaatt aaaccaagca acggatacag tcatcaacgg tgcaacaggg attttaatgg
    28381 tagaaaaaat ggctgcatgg attcttctgg ctttcgcagc atttgcgtgc ttttatattg
    28441 gggaagaatt tcaaaacggt acgattcgca atacgttatc tttaggacgg aatcgaatga
    28501 cttattatgt gtcgaaactt ctcgttacgc ttttgatcac aacacttggc gtggttttga
    28561 tcacgggact agccatgctt gcttacacac ttgctttcgg atttggtgaa gttgagggaa
    28621 tcaaaaacta tggaaattat gttctaaaag tatttcctgt attgcttctg ctgacattag
    28681 ggacattatc tgttccagtg gctttgacat tcatcactag aagtaccagt gtcagtttgc
    28741 ttctttcttt tctttatatc atgggaacgg ccttcattcc cggtgttttc gcaaaaatca
    28801 aaggcttgga atttctaacg gagtggttta cggaaacgtg gctcatgtat acggactttg
    28861 cgcaacaagc aacttattcg caagcaccga aaatgattct ggtcagtcta gtaacaatcg
    28921 tggtatcatc agctctagga atgtttattt tccaaaaatc tgacattaag taggtggtcc
    28981 tgctggaaac tattttgatt atcgaagacg atgaagctgt tcattcctta ctggaggagg
    29041 ttcttgaaca gagatacaaa cttcttgatg cttattcagg tacggaagga aaattattgt
    29101 taagcacata tcctgtcgat ttgatccttc tagatctcat gcttccaggg ctttcaggtg
    29161 aagcattgtt agcagaaatc cgacagacat cgaatgttcc gatcatcgtt ctttcagcaa
    29221 aaagcgatca aagagataaa gtttccttgt tggcagcagg agcggatgac tatgtgacga
    29281 aaccatttga tatcgaagaa cttttgttac gaatcggcat ccaacttcgt catcagactt
    29341 ctgtccaagt aaaagatctg tcgcaacgca tctattacaa ggaaatctta ctggacaaag
    29401 agtcgaggga tgtaaatgtg aatggtgtgg ctgtccattt gacaggaaga gaattcgatc
    29461 tgctgaagct ttttttagaa catccgaaaa aagtattttc gcgagcaaat ctttatgaaa
    29521 cagtttggca agaaccatat tttgatagtg agaaaacagt gaatatgcat atttccaatc
    29581 ttcgagggaa gctagcaaag gcacatgctg tgtatattca tacggtgtgg ggagtggggt
    29641 ttagatttga ttaaatggct gttgcttctc gttgttatct ttatgggaag ttttattttc
    29701 ttcctgcaaa gggaaatcaa gagattaact aagaaaatcg ccactctttc tgaacgacaa
    29761 gaatatggtg gtcgtctttc agtcgaattt cgagaaaaga atctaatgga cctagtagat
    29821 gcactgaata catggttgga tgaaaatgaa caaaaaggac aagcatttca agaaatggaa
    29881 gaaaacatca gactatcgat cgtcggcctt tctcatgatc tcagaactcc tttgactgct
    29941 attaacggtt atgtacaatt actggaacag gtagaggata cggagaaacg ggagaagtat
    30001 ttaacgatca tcaaacaatc tgttgcaaga ttactcagta tgacggatca gttttatgat
    30061 cttgctcgaa tagagacgaa gcaaaaagaa atggatctcc atacgctttc tttttctaaa
    30121 gaggtggaag aagtattttt ctctttttat gaacaatttt ctgagaaaaa tatcgaggta
    30181 gcgttcgctg aacactcgat aaatacaact gtattagcag atccgctcat gttgctgcga
    30241 gtgctgcaaa atatcataca gaatttattg cgttatgcag atggacaagc aaaggtgaca
    30301 ttttcaaaag aggatccatt cattcgatta acagtggcca atcctatcaa accaggaacg
    30361 caaacctctg ttgaaaaagt cttccagcgt ttttataccg aaaataccag ccgcacaaat
    30421 acggaatcta gcggaatcgg gctttacctg tcaaaaaaat tggtggaagg aatgggagga
    30481 gagatgaccg ctagattaga cgggggcatc ttctccatct ccgtcaagtt gcggagggtt
    30541 taattataca agattagtga gaactagtag aaaaatgtat tatcttatat atatttaata
    30601 gagaaaaaag cctgtgatat aaatattgca ggctttttta ttgatttgaa ataatcaaga
    30661 atattagaaa cttctacatt aatcaagaac tttcttctgt atgaaaatag agataataat
    30721 tgtacactta agctgtattc aggaggtgaa gataatgggc atcgaattta gcgaacggca
    30781 aatgaaaata ctatactttt tgattgaaaa tgagcacaca acttacaaag aattatcaga
    30841 acaattatat gtatctacga aaacaattag caaagatatt ttaattttga aagaaataat
    30901 ccaaaaaatg ccagatgtac aaatgttggt tcaacctaaa aaaggcgttt cgcttattgg
    30961 aaaaaaagaa acacttcgaa atttattatc cagtcataaa atcaatatcg cagactctcc
    31021 ggaggaccgt ctaacttatg tgtttgctaa attattgaat actaatgatt ctctaaagat
    31081 tcaaaatctt gctgacgaat tatacgtgag caggtcgacg gtagaaagca caatgaaaga
    31141 tgttagaaaa agactaaaca agcatgggat gtccttagtt tcagatcgaa atggcgtgcg
    31201 catcaaagct gatgaaaaaa gtaaaagaag gttgatgtca gaagttgtga actattattg
    31261 gggtggcttt acagcatcta acagtaaaac agatctctta gacttgaata tcaatttcat
    31321 tggtgaagcg aataatttct taaataagga catattgaaa aaagtagccg aattgcttaa
    31381 tcgatacatg aataagacac aattgaaatt tacagattat gaatttcaaa ctttagctat
    31441 ccaccttgct attgcgatag aaaggattga aacaagcaat ttcttatcac gtagtaataa
    31501 ttctgaagaa gaaatctcaa agaatacact tattttaatc aaaatgattg aaaaagcatt
    31561 ttcaattatt gtgccaatag atgaacaagc ttatgttgac attcacatta cttcgattga
    31621 aaaaaatgct atgaatcacg acttagatca aacgaagctt tcctatttag atatgggtgt
    31681 tgagctacaa gagttagtaa gaattaaatt aaatgaattt tatcctgatg aagaattgat
    31741 caataatcta gtattacatc tcaatgcagc agttaaaaga ctcaaattgg gagtaaatat
    31801 ctataaccct tatacggaca aaatcaaata ttcttttaaa aggtcattta tgataagtgt
    31861 agatttatta gaggaaatcg aagagagatt ctgtatacat tttaatgaag atgaaatcgc
    31921 ttacgtaaca ctccatattc aatcactttt ggatcgttac aaacctgaca aaacgaaagt
    31981 gatattagtt tgtagtagcg gatatggaac atcaaaatta ttagagcaaa gaataaataa
    32041 cggttttgca gatatggttg agatagaaga tgtactaagc atcaatgaac tacaagatag
    32101 aaaagtcact gatgaacttg ttataagcac gattccgatt gaaaatacaa attttcctgt
    32161 tattgttgtt agtcctttga tgttaggggc agatgtcaga aaagtaaaac agtatctaca
    32221 gttaaatgaa caaacagaag atgcttttct aaatttatta gataaacgat tttgcttttt
    32281 tacccaccaa ataaaggata atcaagtgaa cgttttaaat ataattacca aaaaattggt
    32341 aaaagaaaat tacgcgaaag aagggatact agagggagca atcaaaagag aaaaactatc
    32401 ttcaacagcg atgaatgatt ttgctatgcc gcatatcgaa gtagatttta taaaaaagcc
    32461 agtaatctgt gtctacgtta atccagaagg aattgattgg gatgggacac ttgttcattc
    32521 tgttttcttt tttgcactta atgaaaaagt aaaacctgaa ttgaataaaa tttatgaaac
    32581 attcaatgaa atcgcttcga atcatgagtt attagcaaat ttaaaaacga gttcgtcgtt
    32641 tgaaaaatta gtttatatat tgaaagaagg cttataaatg atcagtgaaa aaatcaatat
    32701 aaataatata gtgatagatt taaatgcatc tgataaaaaa agtgtagtcg aaaaattatc
    32761 gaaattgtta gagactaatg ggtttgtgtc tgaccacaaa caatttcaaa aagacgtatt
    32821 tgacagagaa aaccatatga ccacaggaat tgggaaaaat atcgccattc ctcatggcaa
    32881 aagcctagca gtaattgaat caacagtggc tgtagccaag ttaaagcggt ctgttgaatg
    32941 gggcgcatta gatgatcaac cagttgatct cgtctttttg ttagcaataa aagacactga
    33001 taaaggtact aatcatttac gtattttagc agaattatct ggaagattga tggatgacga
    33061 gtttgttaaa agaataaaag attcgagaaa taaaaaagaa ttggtaaaag ctctatcatt
    33121 ttaaaaggag gaatttcata tgacaaaaat agtagcagta acagcatgta tcgcagggat
    33181 tgcccatact tatatggcaa aagctaattt agaaaagttt gcgaagaaga aagggttaga
    33241 tattaaagta gaaacacagg gggctatggg gatagaaaac aaactttcaa tttcggatgt
    33301 ttccgaggca gatgttgtca tatttgcagt agatacaaat gtttcagaac gaggtcgctt
    33361 tgacggtaaa ccgattttaa cagtagggac ctcagaggta gtaaaagatg gtgaagagac
    33421 gattgatgaa gcaattgcat taattaacaa ataaaaaata tatcgtgggg gagttactaa
    33481 tggaattcaa gaaacaagga agagaaattc taaatcattt ccaaagtggg gtttcctata
    33541 tgatcccgct tgtcgtagca gcagggttac taacttctat tgcagtcatt tttggtggca
    33601 caggtgtttg ggaccagacg gatacattct ggggagtcct gcgaatgatt ggtcagacgg
    33661 gattacagtt tatcgtaccg atgatttcag cctatatcgc atattcaatt gctgaccgtc
    33721 ccggtctagc accagctttt atcactggga tgatgtgtca aaatcttggt atgggattta
    33781 ttggaggaat ggttgctgga ttagcttgtg gctatttagc taatgcattg aaaaaagtaa
    33841 aagtaccgat gcaagttatt agtctaaaat caattatgct gattcctttt gttactacat
    33901 tagttgttgg aatcatatta tggtatgtac tagctacgcc tattcaagca atgacaacag
    33961 gactgactaa ttggctagaa ggcatgtcag gagcaaatgc tgctttgatg tcggctattt
    34021 taggaggaat gatggcgttt gatatgggag gacctatcaa taaaatcgca tatgcttttg
    34081 gggttgcttc tttttcaagc ggaagctttg gacctagtac agccatgtta ttaggaattg
    34141 ctattccgcc atttggaatg tttttagcaa caattttaaa caaaaaactt tatgatgaat
    34201 cggaacgaga taatgcaaag acagctatga ttatgggcct tgtggggatt actgaaggga
    34261 cgatcccgtt tgccgtgaaa gatcctttac gagtaatacc aagcatcgtg gtgggcactg
    34321 cagtagcatg tggtctaaat ggattttttg gtgttactca agaaacaatg ctttcaacct
    34381 ttatggcaat tccttttgtt acgaatatac ctttatattt agtatcaatt gttattgggg
    34441 gagtggttac agcgttaatg gtcaatgcac taaaatccat caagtataaa aaagaacaac
    34501 aagtaaattc agtagaagaa ggaaagtagg agaatctgat atggtaaatg cacatataat
    34561 tcaacacacg cactgggaca gagaatggta ttttacaaat gaagatgcca tcgtattgtc
    34621 tgatcaggtc tttactgaag ttctagatga attggaaagg aaccctaaag taaacttttg
    34681 tttagatgga caaacttcaa tcgtcgatga gtatttggag atcaatccgc aaaagcttaa
    34741 ggttatccaa cgactgatga aaacaggaca actattcgtg ggaccgtggt atgcacaaac
    34801 agatgcctta ttagtggatg ctgaatcaat tttaagaaac ttaatgattg gaatcagtga
    34861 tacgatcctt aaatatggag atccaatgat ggtagggtat ttgcctgaca cgtttgggtt
    34921 caatgcgaat ttgcctacac ttttgcatca agtagaaatc gataatttca tgtgttggcg
    34981 aggattaaac tttgaaacga tggttccatc tccttatttt atctggaaag gattgggaga
    35041 taaatttgtt tatgccatga attttccatt tggttatatg actggaatga tgaccttaga
    35101 cgcaattaaa gatattcctg aatttgcaaa agaaaagttg gatgaagcag ttgaaatgct
    35161 tcatatgcaa ggaaaaaaca aagatatttt agtaccttcg ggtgtagatc aaaagtcaat
    35221 gattttaaat tttgatcaag tcgtagagaa gttgaataaa tacagtaaat tccacaatat
    35281 tatttcagat tatccttctt atgtagaagt tatcagaaac aaaaaagaat tacctgaata
    35341 taaaggtgaa cttcgtcagc cggtttactc tcgtgttcat cgttctattg gctcagtaag
    35401 aacaaaaatg aaaatagaaa attttaaatt ggaacaaaaa attctaaaac gagttgagcc
    35461 gctcatgctg attgcagaaa gaaatggtat ccatatcagt aaaggcctac ttcgtcggtt
    35521 atggaaaaag attttgcaaa accaggctca tgatagtatt ggtggctgtg tttcagataa
    35581 tgttgcggaa gatattttcc atcgaatcaa agaagctaat gagatagctg acggaatcga
    35641 aaaccttatt gtaaaacgga tggctgatgc attaaagcta aaatcgaatg aagtccttgt
    35701 tttcaacaca acgactgaga attatagtgg atcgaaaatc gtgcatgtag tagctgattc
    35761 aaagaaaata cacttcaaag gtagtcccta taatatcatt gaaaaagaag tttattttcc
    35821 agaacggaaa aatgcttatc ggatgattgc tacaggtttc gaatattttg atgaaccagc
    35881 ttattatgaa cttgacataa aaataaatgt aaatgtgcca gcactaggat acactgttgt
    35941 tgaatttgag aaaaataatg aaaaattaga aacagcaatc gagatagaca aaactgagat
    36001 aagtaacaat aaatataaac tttcttttaa agatgggcaa ttgaatttga tagttggaga
    36061 tagacaatat cttgatttcg ttcatttgat cgattcagca aatgatggcg atacgtatga
    36121 ttattcacca ttagaaggag atacagaact atctctaaaa ttagaaacag ctaaagtata
    36181 taaagattct ttacaagaaa cattagttgt ttacggaaaa gctcaacttc ctaaagattt
    36241 aaaagatcgt ttatctgaaa aacccgaaat ggaagaaata tcttatgaaa tatcgttcag
    36301 tctgggagaa agtcaaatcg ttgaaggcac actcaaaatt cataatactg tttactcgca
    36361 tcgtatgcgc ttagcaatta atgttttaga taaatctgaa aaatcaattg cacaaattca
    36421 aaacggattt attgaaaata cccctgatgt cattcctccg aattggtcag aaactatggt
    36481 agagaaacct gttaatttag aaatattcga taagagtgtc tctgtggcag aaaatgatca
    36541 ttattttacg ttttatgcag atggtttaaa agagtatgaa cgtatagaaa atcaattaat
    36601 cataacctta ttttcaacaa caggggaact tggaaaacct aatcttgctt ggcgacctgg
    36661 gcgagcttca ggagatacga caaatgaagg gcatgtcatg atggaaacac cgctagctca
    36721 agagataggt gagtataaag tcacttttgg atttaatgta gaagaaggaa gatttaatga
    36781 gttcaaagtg gcaaaacagg cagaaaaacg gttagaacaa tctatttctt atcaaaagca
    36841 gaaactgaat gtatttattc acaggttaga taacaagatt tggccattac aaaatgaact
    36901 tgatgttcct cgtaaatttt cattgattga attacctgaa gacttaattg tatcatcgat
    36961 ttatccttct tattttcatg aacaaggatt tgttcttcgc ttagctaatc caacagaaca
    37021 agaaaaaata gtacctgagg ctatcctttc ccttgggaca gttgtcaatg cactggagaa
    37081 taaacaagaa ttaacaacaa ttcctcccta tgattatttg tcaattttga taaatgagag
    37141 ataaatatgt aatatacaag aaaaaaacac cttttatttt gaaaggtgtt tttttaccct
    37201 cttttcaaat agcgcaacag tgctatacta aagctaacaa ataaaggaac ggagagggat
    37261 atgggtcaaa gagaatttat cgttttaatt attattgcag ctgttatttt attagttgct
    37321 ttagacattt tttcacgttt gaaattaaag gaaacagttc gtagcaaatg ggaaaaaatt
    37381 ccttatcaac cgagatttga taaagaagaa agcttgaagg aagcatggct cacggagaag
    37441 aagttccgtt catgggatag cgaaatcgat gatcttactt ggtatgacct ggatatgttc
    37501 gaagtattcg aaggaatcaa cagtacctat tctagtgtag gttcagaagc gttgtatcaa
    37561 cgtttacgca gctttgattt tggtgaagat cagcagttag aaaaactgat tgctttttat
    37621 caggaaaatc ctcaactgag agaaaaaatc caatatcaat tcgctcgttt aggaaaaaaa
    37681 gatcataatt ttgcaaaaca atatctagcg gatggaaaaa gtaaaaagat tggacgcgta
    37741 ggtttattta tttttcttgg cttgcttccg ctggtgggtt tgggtttgct tcttttagga
    37801 caagtactag gaatctattt ggcaatcggt gggttagtat tcaatacggt ctattatcta
    37861 gtgaagaaac aaacactaga aacagagctg aatagcatga gttatttggt ttcaacgatt
    37921 tcagccgcca atcagctagc aaaactgccg acaccacttc aagaagagct gaaacagcaa
    37981 actaaaccat taagagacat ccctaaatta ggtttttcat ttcgtatgaa gagtgggagt
    38041 gaagcagagt tgatttttga atatgtcaac atcatgttca tgctgccatt tatctcctat
    38101 catttcgttc tcactaaatt agaaaagcat tcaactgaag ccatcaagct gtgggaattg
    38161 ctgggagaat tagaagtagc cgctgcaata ttgaattacc gtacttatat gcccatcact
    38221 tgccgaccag agtttactga gggcggtgtg acagcgaaag atatctatca tccattgtta
    38281 aaagaagcgg tagtgaatcc ggtcaactgg cagaagaata cattagtcac gggttccaat
    38341 gcatcaggaa aatctacgta tgtcaaaagt atagccatca gctgtattct agcacagacg
    38401 atccaaacag cgattgcaga acagtttacc ctgcaacctg gacatgtgtt gacttccatg
    38461 gcaatcgaag atgatttatt tgaaggcgac agttattttg tttcagaaat caaatcgatc
    38521 aaacgtttgt tggaccaagt ggcttccaaa gaacgctgct actgcttcgt agatgagatt
    38581 ttaaaaggga caaatacgat cgaacggatt gcttcttccg cttcagtcgt tcggtggctt
    38641 gcggagtatc catctttagc atttgtcgcc acacatgata tcgaattgac agagatttta
    38701 aagaattatt gtgagaatgt ccactttgaa gaacaagtaa cagaaggaaa aggaatcagt
    38761 tttgatttca aattaaaaga aggaccttca aggacccgaa atgcgattgc cttgctgaaa
    38821 gttttggatt acccagagac tttagtagaa accgcaaaaa cggaagccgc gttatttgat
    38881 gaaaagcggc agtggcatgt attgggatag gcgaagtgat cgaaagtatt tattggatca
    38941 aaaatcttgg cttttgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc
    39001 tttacttttg tctcacgctc cttttgttgc acatatgaat agtaatcctt tatcttcgat
    39061 ttgttttttc tgaaaaggtt gtctgacttc gtccgattga tgtctttcat taggagattt
    39121 tcctgagccc agcaacctga tttttcgctg gaaccaagtt gttttttcat ctgctgtatt
    39181 ccatgataca ataaagaatc atgtctataa ggagatagga aataaatggc aaatgcgctt
    39241 gaaataaata atttgaaaaa ggtttatgga agtggggtcg aagcattgcg aggaatcgat
    39301 ctttccgtga aagaaggaga tttctatgcg ctattaggac caaatggagc tgggaagtct
    39361 acaacgatcg gaatcattac ttctttagtc aataaaacat ctggaaaagt gaatgtcttc
    39421 ggttatgatc tggatacgga tctagtccga gcaaagcaac agattggatt agtcccgcaa
    39481 gagttcaatt tcaatccctt tgaaacggtc cagcaaatcg tcgtgaatca agcaggctac
    39541 tacggtgtct ctcgcaaaga agcgatgaaa cgcagcgaaa aatatttgaa gcagtccaat
    39601 ctttgggaaa agagaaatgt ccgtgcacgt atgctttccg ggggaatgaa gcgaagactg
    39661 atgattgcta gggcattgat gcatgaacca cgtttgctga tcttggatga accaacagca
    39721 ggagtcgata ttgaattgag acgcgagatg tgggagtttc tccgagaatt gaacgaaaat
    39781 ggtacaacga tcattttgac gacgcattat ttagaagaag ctgaaatgct ttgtcgcaac
    39841 atcgggatca tccaatcagg tgaactgatc gagaatacta gtatgaaaga gcttctatcc
    39901 aaactgcaat ttgaaacatt tatctttgat ttagcgccat atgagaccaa acctgtgatt
    39961 gaaggatacg cttgtacatt tgaagatgaa cagacaatcg ctgtcgaagt tgaacgaaat
    40021 caaggggtga acggaatctt cgatcagctg acaagacaag gaatcaaagt tctttctatg
    40081 aggaataagt cgaatcgttt agaagaactg tttttgaaaa tcacagaaga aaataatcat
    40141 acggaggaga aaaatgttta atctttattt tactgcatta aaaagtttag ctatcaagga
    40201 aacgaaccgc tatttgcgta tctgggtcca aacactggtt ccgcctgtga tcacgacatc
    40261 cttgtacttt gttattttcg gaaaaatgat cggtggtcgg atcggtgaca tgggtggttt
    40321 ttcatatatg gaattcatcg tgcctggttt gattatgatg tctgctatca ctagttcgta
    40381 tgccaacgtt tcttcgtcct tcttctctca aaaattccag aaaaacatcg aagaaatctt
    40441 ggtagcgcct gttcctacgc atgtgatcat ttggggcttt gtgattggcg gagtgggtcg
    40501 cagtattctc gtcggctctc tcgtaacgat catttccttg ttctttgtac cacttcatgt
    40561 gtattcatgg ttcatggtca tcattacatt attgatgacg gcaatcttgt tttcgttagc
    40621 aggactgctc aacgggattt ttgctcagtc ttatgacgat gtatcgatcg tgcctacatt
    40681 tgtcttgcag ccgttaactt atctaggtgg cgttttctat gccatctcta tgttgccgcc
    40741 attttggcaa gctgtttcga aagtcaatcc gatcgtttat atgatctccg gtttccgtta
    40801 cggattcctt ggaacaatcg atgtgccagt agcaacatcg atgatcgtac ttgtgctatt
    40861 catcgttgtt ttgtacgccg ttacttggta tttgatcaat aaaggaagag gattgagaag
    40921 ttagaaaaga ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaacgggaaa
    40981 atagttcctc atattttgtc gtttgttgag ctaataccga gggtcagctg attgaacacc
    41041 gtttagtg
//
LOCUS       DADQCX010000015        39320 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.015, whole genome shotgun sequence.
ACCESSION   DADQCX010000015 DADQCX010000000
VERSION     DADQCX010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.015"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            37..1329
                     /locus_tag="J8R83_000738"
     CDS             37..1329
                     /locus_tag="J8R83_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9573889.1"
                     /translation="MLALGGAIGAGLFKGSGEAIGIAGPSVLIAFLIGGLILYIVMKG
                     LGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIINIIAEAVAAASFLQLWF
                     PHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVIILLIIFATYLVGQQML
                     GTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELIAITVSEADDPKRAIPK
                     AIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFEKMNIPFAADIVNFVIV
                     LALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQRAVLFCTSVLYLGVAL
                     SYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLWDKGISFFALAVLGLIF
                     LGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1547..1990
                     /locus_tag="J8R83_000739"
     CDS             1547..1990
                     /locus_tag="J8R83_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAZ9573890.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2494..3912)
                     /gene="nhaC"
                     /locus_tag="J8R83_000740"
     CDS             complement(2494..3912)
                     /gene="nhaC"
                     /locus_tag="J8R83_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAZ9573891.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4315..5538)
                     /locus_tag="J8R83_000741"
     CDS             complement(4315..5538)
                     /locus_tag="J8R83_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAZ9573892.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5569..6408)
                     /locus_tag="J8R83_000742"
     CDS             complement(5569..6408)
                     /locus_tag="J8R83_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAZ9573893.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6425..7105)
                     /locus_tag="J8R83_000743"
     CDS             complement(6425..7105)
                     /locus_tag="J8R83_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573894.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7107..8180)
                     /locus_tag="J8R83_000744"
     CDS             complement(7107..8180)
                     /locus_tag="J8R83_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9573895.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(8827..9498)
                     /locus_tag="J8R83_000745"
     CDS             complement(8827..9498)
                     /locus_tag="J8R83_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9573896.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9585..12263)
                     /gene="mgtA"
                     /locus_tag="J8R83_000746"
     CDS             complement(9585..12263)
                     /gene="mgtA"
                     /locus_tag="J8R83_000746"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAZ9573897.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            12922..13359
                     /gene="ndk"
                     /locus_tag="J8R83_000747"
     CDS             12922..13359
                     /gene="ndk"
                     /locus_tag="J8R83_000747"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAZ9573898.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13381..14247)
                     /locus_tag="J8R83_000748"
     CDS             complement(13381..14247)
                     /locus_tag="J8R83_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9573899.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(14407..16500)
                     /locus_tag="J8R83_000749"
     CDS             complement(14407..16500)
                     /locus_tag="J8R83_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9573900.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(17249..17872)
                     /locus_tag="J8R83_000750"
     CDS             complement(17249..17872)
                     /locus_tag="J8R83_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573901.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(18031..19428)
                     /locus_tag="J8R83_000751"
     CDS             complement(18031..19428)
                     /locus_tag="J8R83_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9573902.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(19460..20431)
                     /locus_tag="J8R83_000752"
     CDS             complement(19460..20431)
                     /locus_tag="J8R83_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9573903.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            20805..21230
                     /locus_tag="J8R83_000753"
     CDS             20805..21230
                     /locus_tag="J8R83_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573904.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(21718..22419)
                     /locus_tag="J8R83_000754"
     CDS             complement(21718..22419)
                     /locus_tag="J8R83_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAZ9573905.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(22435..22875)
                     /locus_tag="J8R83_000755"
     CDS             complement(22435..22875)
                     /locus_tag="J8R83_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAZ9573906.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(22875..23450)
                     /locus_tag="J8R83_000756"
     CDS             complement(22875..23450)
                     /locus_tag="J8R83_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAZ9573907.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(24298..24777)
                     /locus_tag="J8R83_000757"
                     /pseudo
     CDS             complement(24298..24777)
                     /locus_tag="J8R83_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(24936..25637)
                     /locus_tag="J8R83_000758"
     CDS             complement(24936..25637)
                     /locus_tag="J8R83_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9573908.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(25745..27154)
                     /locus_tag="J8R83_000759"
     CDS             complement(25745..27154)
                     /locus_tag="J8R83_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAZ9573909.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(27202..29067)
                     /locus_tag="J8R83_000760"
     CDS             complement(27202..29067)
                     /locus_tag="J8R83_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9573910.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(29188..30039)
                     /locus_tag="J8R83_000761"
     CDS             complement(29188..30039)
                     /locus_tag="J8R83_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9573911.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(30349..31062)
                     /locus_tag="J8R83_000762"
     CDS             complement(30349..31062)
                     /locus_tag="J8R83_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAZ9573912.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(31130..31456)
                     /locus_tag="J8R83_000763"
     CDS             complement(31130..31456)
                     /locus_tag="J8R83_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAZ9573913.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(31579..31806)
                     /locus_tag="J8R83_000764"
     CDS             complement(31579..31806)
                     /locus_tag="J8R83_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAZ9573914.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(32128..33381)
                     /locus_tag="J8R83_000765"
     CDS             complement(32128..33381)
                     /locus_tag="J8R83_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9573915.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            33442..34182
                     /locus_tag="J8R83_000766"
     CDS             33442..34182
                     /locus_tag="J8R83_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9573916.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(34268..35026)
                     /locus_tag="J8R83_000767"
     CDS             complement(34268..35026)
                     /locus_tag="J8R83_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAZ9573917.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(35023..36051)
                     /locus_tag="J8R83_000768"
                     /pseudo
     CDS             complement(35023..36051)
                     /locus_tag="J8R83_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(36071..39238)
                     /locus_tag="J8R83_000769"
     CDS             complement(36071..39238)
                     /locus_tag="J8R83_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573918.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
BASE COUNT        11194 a         8294 c         6718 g        13114 t
ORIGIN      
        1 aaattgaaaa aacaacttag ctccagacat atcaccatgt tagctttagg tggagcaatc
       61 ggtgcaggtc tatttaaagg aagtggcgaa gcgattggga tcgccggccc ttctgtattg
      121 attgcttttt tgattggtgg gctgatttta tatatcgtga tgaaaggtct gggaaaaatc
      181 gttttaagcg gtggcgacac gcatcacgga ttatctggtt tgatacgccc ttatctaggt
      241 gctcattctg ctgattttac tgattgggtc tactggtcta tgtggattat caatatcatc
      301 gctgaagctg ttgcagctgc ttcctttttg cagttgtggt tcccgcacat tccagcctgg
      361 gtatttgttt ttatgttggc tgttttaact acgatcatca atctttattc ggtacggtta
      421 ttcgcagaaa cagaatattg gctggctttt gctaaaatca gtgtcattat cttactgatc
      481 atttttgcta cttatcttgt cggtcagcaa atgttgggca caggcgtttt ccctaccctt
      541 cagcaattga ctgaccatgg tgggtttact cctcatggta tgaagggaat catcagttct
      601 ttgcttgtag ttatctattc ttacggcggt tctgaactga ttgctatcac ggtaagcgaa
      661 gcagatgatc ctaaacgtgc gattcctaaa gcaatcaaag gtgtcatggg aagaatcatt
      721 tccttttaca tcattccttt gtttttgctt ttgattcttt ttccttggaa tactttagca
      781 ggcacgaatg tcagtccttt tgtgatggta tttgaaaaaa tgaatatccc atttgcagcg
      841 gatatcgtca attttgtgat tgtccttgct ttgttctcat ctatcaattc gggtgtgtat
      901 gcatcttcaa gaattttgtt cttccgtttg aaggatcgaa aaggttcctc tagaaaacta
      961 gctgttttaa acaagcatca agtaccgcaa cgtgctgttt tattttgtac cagtgttctt
     1021 tatcttggtg tagctctttc ttattttgtc ggtgacaaat tatttggcta tctggcaggt
     1081 tccctttcgt atacagtatt attgatctgg atcattatca gtgcggcatc ctttgtactg
     1141 gcactaagaa aaggaacatt atgggataaa ggaatcagct tttttgcatt agctgtctta
     1201 ggattgattt tccttggtat cctgttcacg aactccattg gggtaactgt attgactggc
     1261 ctgctttacc tgttcattta tttcagttat caaaaaaaga atgatgcgtt cgtattgacg
     1321 aatgaatgaa atcgatagaa aattttattt tatttatgtg gaatagatgg agctattgaa
     1381 gaaaggagtt gtgacaaaag tcttgttgca actccttttt ccgaataaac agtctcatga
     1441 cctcttggta aacggtgttc aaaaaccctc tgtgcaaaat aattgattgt tctccatgct
     1501 catgacatga tagaagaaag gaatgaaaaa aaggagtttg ttttaaatga aaaagtattg
     1561 gaagtttttg ttgatgatcg gtgtttcaac ggtagttatg tttggtatga tgtacttgaa
     1621 tgtctatgcg ctcgatcata tcttcttcag tcgtacacga gtattcatgg cgttgatgat
     1681 gggtgcagtc atggcagtca tcatgctgtt gttcatgtgg aaaatgtatg aaaacaaaaa
     1741 gataaatgtt atgatcttag ccgctagtct tcttgttttt gccggttcct tgtttatggt
     1801 acgaagccaa actactgtca acgacacagc ttggatgaag gccatgattc ctcatcattc
     1861 tatcgctatc ctggcaagta aacgagctga tttaaaagat cctgaagtaa aaaaattagc
     1921 ggaagaaatc attcaggcac aagaagaaga gatcgacaaa atgaaaaaaa tgatcaaaga
     1981 aatggaatga ccattatccg tccaaataaa aaaagaggat gttccagaag ttatcagctt
     2041 caagaaataa gaagaagcta cttctggaac gccgtgaata aggggttgtg aaaaagctgc
     2101 cctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcctatttt tcgtttggtt
     2161 aggcttatta ccgcagatgc aagcttttga acaccgttta ttaagaggtt gtaaaatcag
     2221 cgttctgacc tgagtattag agagacaaat ggaaaaatag ttcctcatat tttgccattt
     2281 tttgagctaa taccgagggt cagctgattg aacaccgttt atcgagaggt tgtgaaaaag
     2341 tcgcttagtt tcgcgtatta agaaaaattt tgtgaaatgg ctttccacat ttttgtataa
     2401 atttggctta ataccgagaa actggctttt gaataccgtt tattcgtaaa agggattgtg
     2461 acaaaagtct tgtcacaatc cctttttatg tttttattgt tctaattgcg ctgtcttgct
     2521 tactgcttct tgcggtttca caaatttttt tgagattccc caacctgtga aggcactgac
     2581 catcgaaaac acaggagaaa gcaaactgaa aaatacgaat ggcaagtaag tgagtgtagg
     2641 aataccaaat gtacttgcta cgaaacttcc ggcaattccc caaggcacta agtagttgat
     2701 tactgttcca ccatcttcta gcgttctacc taatacagtt ggatcaaatc ctgctttttc
     2761 ataagtttct ttaaatgcat taccaggcag aataacagat aggaattgtt caccaataaa
     2821 aatatttact ccgatacttg tcatcaatgt tgtaaaaatc aaatttggtg tgttcgtcat
     2881 ctttcttgat actcgttcca tcacggttga gatcaagcca aattcgatca acaatccacc
     2941 taatgacaaa gttagaataa tcaatgacac agtaggcatc atactttcga ttcctccgcg
     3001 gctaagcagt gaatcgattt gttggtttcc agtatttgaa acaaaccctg attcgatgac
     3061 cccagccaac ttcgttaagg aagtttgtgg gttttgaata aaaatcattc ctactgctac
     3121 agcgatattc aacaaaatcg ttaaaattgc cggcaccttt ttccatgcac acagtaacat
     3181 taaaaataaa ggaatcagtg accagattga aatagtaaag tttgcttcta gaacatcagt
     3241 cacttcacga atagatgaaa gacttgcggc tttacttgtg tgtcctaaaa tcatgaataa
     3301 aaagaaagaa acaacaaatg ccgggacagt tgaccacatc atatgcttga tgtgtttgaa
     3361 caaatcggca tcaacaatag ctgctgctag atttgttgat tcggataatg gagacatctt
     3421 atctccaaaa acggcacctg aaacaatagc tccaacaacc agcgctggat ttaagcctag
     3481 tgttgtccca ataccgaaaa atgcaatccc aatcgttgac ataacagtaa aggcactccc
     3541 tacagcgcta cctacgattg cacacacaac aaatacagaa gggacaaacc actggacact
     3601 gatcaatttg aacccaatga ccattagagt tggaatgatc cctgcttgta tccatacagc
     3661 aatcaatgaa ccgactaaaa taaaaataaa gattgggatg attcctggtt tgatgccatt
     3721 gatgattcct tcgtgcagcc aatctgtcgg gtatcttttt atcactgcat acaacatgac
     3781 cattccgatc gctgctaaga tcgtgatatt aggtgagacc tttaatccga caacgccaat
     3841 cgcaatgcct aaaacaataa ccattaatac aagtgttgct tctaaaaaac ttggtgttcc
     3901 tttttttccc atgataatct ctcctttttt agttgttctt atgttctaaa aaagttaaga
     3961 tatcggatta ctccgccgca attcatccgc gattcctcct ttataaaaat aaaaagacct
     4021 gttttaaact aaggacgaat gactccgcgg taccacctta attaaaaaca gatctgtttt
     4081 tcactttcaa acttttattc aaatgtatgg actttccatg taattcgtca attaggcttg
     4141 atcggttcac agcgaccacc gactttctga acaaaacacc taaccgctac tgcgtgaaaa
     4201 gttgacttgt acgaagttta ccttccataa gatcatttgt caatgaaaaa gaaaatattt
     4261 tttcattttt ctgaaaatta tttttataac tttcacacac aagtttattt tttactagaa
     4321 agtagcgccc tcttgttttt ttcttgctac tatttcttga tgttcttgct tgattctttc
     4381 taatagcttt ggctctttca acagatcaag agctgtattg gcgagtagtt ctgctgcaat
     4441 cgcaatagaa gcaaggcctt tgtcactttt agcagcagct ttgaattctt ctgtgtgtcc
     4501 ggcaatatat gtctcagaga ttgctaccgt aggctggatt gttggtatga cttggctgac
     4561 atttcctaca tcagaagaac cgagacttgt tctttgttcc gtttctattt cttcatctgg
     4621 aacacctgct tcttttgcat gctggaagaa taagtcatca aaagaaggag taacgatgac
     4681 atcatcaact gcattttgga acaatccaaa ctcaaaagtc gtgcccgtac ttatcgcagc
     4741 acctcgtacg atattttcca ctttttcata tactttatct aatgtttgcc gatttcctgc
     4801 acgtaaatag aaacgtccag cagcgtaatc tggaatgacg ttggcagcta ctcctccgtc
     4861 tgtaatgatc ccatggatat tgacatcttt tggcaattgc aagcgtagag cgttgattcc
     4921 attaaacact tggatcaatg cttccaaagc atttactcct ttttcaggtg ctgctgctgc
     4981 atgggaagcg acaccgtaaa atttgatgtc gactggatca ttcgctaaag attctgtcgt
     5041 tttcccataa cgaaaagctg gatggacgca taacgctaca tcgacatcct caaaaaaacc
     5101 ttctcgaaca aagctgcctt tagctgatcc gttctcgccc ccttcttccc ctggggtgcc
     5161 atatacacgg atttctccac cagtttcatc aatgaattgc ttcactatgc tggcggctaa
     5221 tacggagtaa gtaccaaaca aattatgccc gcatgcatga ccaatacctg gtaaagcatc
     5281 gaattctgcc aaaaaggcaa ttgtgggacc gggtttattg gaaatataac gtgcatcaaa
     5341 ggctgttcgg tgtccagcta cttctttttc tacccaaaac ctttcttttt ctaattgttt
     5401 aatcaacgct gctgaggaat aaaactcata gttacttact tcaggatgtt cgtggatatc
     5461 tagagcaagt gcttgatatt ctggtaaacg atattggatt agatccttca attggtttgt
     5521 tgagattgtt gttgtcataa aaaattcctc ctatgctagt catttttctt attttctccc
     5581 gaatgtttcc catgcaggca cgcttgatcc ttttgatgtt ttctcgatta ctttgactgt
     5641 gtcttctgtt tgataagcgt ctactatttt ttgatacgtt ttattgtttt catcttcttt
     5701 tcttgcaacg atgatattca cataaggacg tgcatggtca tccactggtt ctaagaagat
     5761 ggcatcagaa gcaggattaa atccagcatc tacagctaca ccgctattga tcactgaaat
     5821 gtctacatct gacaaagcac gtgctgtttg ggaagcatct aattcagaaa tgtctagatt
     5881 ttttctattc tcggtaatat cagaaacagt gggcgcttgt ccttttgcct tatccacttt
     5941 gatcaatcca gcagtttgca ataacagaag agctctgccg ccatttgtaa catcattagg
     6001 gattgctact tttgctccgt ctttgatatc agctacatcc ttcaaagtgt tagaataaat
     6061 tcccagcggt gcattgacag tatttccgat cgatactaaa tcagttccgt gttctttatt
     6121 gtaattgtct aaaaagaatt gatgttggaa agaattcaaa tcaatcgatc catctgctaa
     6181 agccacattt ggttgattgt aatctgtaaa tttcacgtat tccaaattaa tgttctcctt
     6241 tttcaaacgg tctttcacgt tgtcccatac atctgtatct tctccaataa tccctagttt
     6301 tacgatagtt tcttttttgt cagttgtatc tgcttttcct tggctacacc ctgccaacca
     6361 aataattgct acaaatgtaa tgactacaaa acgaataatt tttttcattt tttctcctcc
     6421 actttcaatg tgtaattttt ttaatcagtt gattactgat aaattgactt aaaaaaacta
     6481 agattagaat caataatgta gccacaatcg ttacatctgt ttggaatcga ttataccctc
     6541 tcgatatagc aagattccct aatccgcctg cacctactgc tccagccatg gtagtcagtc
     6601 cgatcacgtt gatgatagtc aacgccgaga cccgaatgat accaggcaaa ccttctaaca
     6661 aatacacacg taaaatgata ccgattggac tggttcccat cgcttctgcc gcttcgatca
     6721 ccccaggatc aacttctagc agtgcgttct cgatttgacg agcaaaaaac ggaacaactc
     6781 caaaaatcaa tggcactaaa gctgctttcg caccaatcgt cgttccaact aagaaacgag
     6841 tagtcaatgc taaaagagaa agcaagataa tgaaagggat ggaacgaatg atattgatca
     6901 gcttatcaag tatttcaaat agcagacggt tagctagtaa tccattaggg cgtgtcacta
     6961 ctaacgtcac acctaagatg attccaatca tcccgccaat gaatgctgtc caaaaagaca
     7021 tatatagtgt ttgcttcgtc gcttcgacaa attcatccgg aatcaaataa acattgggca
     7081 aatatgtttt aaagaaatca gtcattttat cttcctcctt cgatcacttt gatacgacta
     7141 tctaaatcgt ttttttgtaa aatatttatt tttacaccag atttgatcaa ataatccaat
     7201 gcttttttcc gctgtttggt ttctccagct aaagtaacga tcaaactccc taacggcgtt
     7261 tcttgtaata actctacatt gccatataaa atattcgctg ttacttgata tttgctgtac
     7321 agatgagcga ttagaggttc gttcgtctga tttccaatat aacttaattc caccagccat
     7381 ttattggcga tctgatcggc aaaagcagaa tgggcaatga tcgtttctaa tgcttggtca
     7441 agatgagtag ctgttcgaat aaaatctttg gtcaattctt cttcaggatt gctgaagatc
     7501 tggatgctgc tacctttttc aacgattctt ccatcttcca taaccgctac cttgttgcag
     7561 atttctttga caacttgcat ctcatgagtg atcaggacga ttgttaaacc taactggcga
     7621 ttcaattttt ttaacaatgc aaggatctga agggtcgttt tcggatcaag tgcactggtt
     7681 gcttcatcac ataataatac cttaggttca ttcgccaaag ctcgtgcgat tgctactcgt
     7741 tgtttttgtc cccccgacag ttgtttagga taagcagatg ctttttcttc caaaccgaca
     7801 agttccagta gttcattcac tttttgacga cgttcctgtt tcgattttcc agaatacttt
     7861 aaagaaaaat caacgttgtc aaaaatagtt cggctttcca ttagattgaa atgctgaaag
     7921 atcataccga tggcctttct ttcttttcgc aattctttgg gagagagctg actcagattc
     7981 gtctgattga caatgacttc tcctgctgtt ggtttctgca gcaaattcat cacacgaact
     8041 aacgtacttt tccctgcacc tgagtaaccg acgattccat aaacatcgcc tttttcaatc
     8101 gttaaatcta cagaatctac tgcctgtatc tctttttctt tttgtttgaa acatacagaa
     8161 acatctcgca attcaatcat taaaattcct ccttatctaa aaaaagcgtc ctcaagaaaa
     8221 tgaaaatgtc attttcttga ggacgctttt ttgcgtgtta ccacctcatg ttcaagctgt
     8281 gttcacacac aactcctctt caagtacgat catactctag caagatatcg gtcgcagccg
     8341 tcatcgcctt acatctatgc tcgggatgaa ttgctcgatg gccattttcc aatagtcgtt
     8401 ccttgcttct tctcagctac cgaagctctc tgtcaaaggt tcttctatcg tacttaccat
     8461 ttcaatgcaa ataatattca aaaaaaaagt ccttttacta acataaacta tgtcagtaaa
     8521 aggacgacgt atcgcggtac cacctttttt cggaagtttc cttccctcaa gcccaacatc
     8581 tcaaaaagag agattggcgt tcgttttaac ggtcgaacag ttccgaattt gcctacttat
     8641 cgacaaatta ttctccaagg ccattttcag cttttcttac ttgactcttc tcaccagcca
     8701 gagcctctct gcaaagtttc caaacttact ttccttttca acgaaatcga tattttgttg
     8761 ttgggattaa tctacatgag gaaaactgaa aagtcaagta cgaaattcaa attatttttt
     8821 ctatatttat ttttctgttt ttttatttaa catttcaata acagttcgaa gatcttttcc
     8881 ttccgcaaga agtttcaatt tttccttttc ttcgacggta taatttcgga caaaactgga
     8941 atcaggtatc aaaacaacgc ctaatcctgc tcgtgaagca gctgttgctc ctactaaaga
     9001 atcttccact gcaaaggctg aactagcttc taatcctgtt cgttccaaag ctgtcagata
     9061 aggaatcggt gaaggcttgt tctccgacac ttcgtctccg aatgtaaacg tgtccaagta
     9121 atcagctaat ttaaagtgat ccaagatatc tgttgctctt ttcgtaacag tggtcgtagc
     9181 aatgcctagt ttcatatgac gttcttttaa gtctgccaat atttcttttg catatggttt
     9241 taagtggatg gctccgcttg tcagctgttg ataaaaatat tcttcacgct tcgctcggac
     9301 ttcctgtact ttttcagggc tacctgctgc tttcactaaa atatcaaaac tttgtttcca
     9361 gttttttccg ccccaagcgt caacgatttc ttttgggata tggatatcaa attgctgaaa
     9421 tccccaaagc cagccatcac gatacgtttt ttctgtgtca actaacaaac catctaaatc
     9481 aaatattgca cctttcatct atacattaat cctttccaaa acaatacaca tagtttagca
     9541 cgactggtcc aaaaagaaca gaagcaaaga accagccttc tcgtttataa gagttcttgg
     9601 aatcgacgga tatagatttt cttcacagct gtcacaagcg ccagataagc gatgactgta
     9661 gcaaataacc ataaccagta attgccagga agtggcatca agcctaattc agcaccaaaa
     9721 cttgtaaaag gaaggacaga accgacaata attcctaatg tagtgataac aaacatggca
     9781 aatgttgcgt tgctttggat aaatggtact ttcggtgtac gcagtgcatg gagcactaag
     9841 gtttgtgtcc atagtgattc gacaaaccat cctgcatgga ataatgcgat gaaaatcact
     9901 cgctgtgaac tatccaatgt atggaaactt ccgcccacta cagcaggaca aataacaaaa
     9961 tacatcaaca agtaagtagt aatatcaaat atcgaacttg ttggaccaaa gtaaaccatg
    10021 aattccccaa tactagatgc attccatttt tttggctcgt ccaaatattc tttatccatc
    10081 cgatcccatg gcaaggaaat gcaggaaaca tcatagatca gattcaaaaa caaaagttgt
    10141 aaaggcagca ttggtaaaaa tggcaggaac gtacttgcaa tcagcacgga aaacatattg
    10201 ccaaaattag aacttgctgt agccttgata tatttcatga tattcccaaa agtttctcgt
    10261 ccagaaagaa ggcctctttc caaaatcgtc aaatcttttt ctaaaaggat cacgtctgca
    10321 gattctttcg caatatccac agctgtatct acagaaatac cgatatcagc cactttcatt
    10381 gcaggagcgt cattgatacc atctcctaaa aatccgacag tatgaccatt tttacgtaaa
    10441 gctgtcgtca aacgtgcttt ttgctgagga ttcaatttta cgaatacttc atggtcttca
    10501 gctacttgtg ctaattcatg atcactcatt tccgagattt tctcaccggt aaccaattca
    10561 ttgatctcta gacctacttg acggcacact gaacgtgtaa ctaattcgtt gtccccagtc
    10621 agaactttta cagctacacc atgttctttc agagctttca acgcttgttt cgttgtttct
    10681 tttggtggat caaggaaagc aagataacca atcaaaacca tgtctgactc atctttgact
    10741 gaaaattctc caacgacgct tggattggtc ttttgtgcga caccaatcac tcgtaagcca
    10801 tcttcattaa gtgactgtac ttttgcaagt acggcttctt ttcgttcttt tgttaatggt
    10861 gtaacagtac cgccaagatc aataaattta gaaatgttca gcatttcttc aatcgcgcct
    10921 tttgtgatca tttgtgtttt accagctgga tcagcaacca caacactcat acgacgacgt
    10981 tcaaaatcaa aaggaatttc atccactttt tgataattga tcttatctgt atctaaagtt
    11041 tctgttgctt catcaatgat agccacatct aacaaatttt tcagccctgt ttgatagtag
    11101 ctatttagat acgcatggcg caaaacacga tcatcttcat ttccttcaca atccatatga
    11161 tattcaagaa tgattttatc ttgtgtcaat gtccccgttt tatccgtaca taacacatcg
    11221 attgcaccaa agttctggat ggcattcaaa tttttgatca ctgttccttt tttggccatc
    11281 acacttgctc ctttgaccaa attcgtcgta acgatcattg gaagcatttc aggtgttaga
    11341 ccaactgcta cagatagtcc aaaaagaaaa gcttctagcc aatccccttt tgtaagccca
    11401 ttgatgacga taactgctgg agccatcaat gacataaatt tgatcagtag catggatgtt
    11461 ttatggatgc ctaattcaaa gcttgattga attggttttt cagatagcgt ttctgctaca
    11521 tgaccaaata gtgtttcatt tccaacagaa acaatgattc cttccgcact tccactgatg
    11581 acattacttc ccataaagac aagattttcg taacttgttt cgctttgctg atcgtcttca
    11641 catactttcg catgcttttc tactggatag ctttcccctg tcaatgctgc ttgggaaatg
    11701 aataaatcct ttgcggacaa taaacgcata tccgctggta tcatatcccc tgctgaaagc
    11761 cgaacaagat ctccacagac gatttcttcc ataggaatct ctgtgtactt tccattacgt
    11821 tttacagctg ccgttacttt cacaagtgat ttcagttttt cagccgcttg attggaacgt
    11881 acggactgaa tcaacgtcat tgtcccgctg acgataacca tagtgaagat aatggctaca
    11941 ccgaaaagat ctttatctcc aggagctgct aatacatatt ccgtgatgaa tgaaataatt
    12001 cctaatgcga tcaacactaa tgtaaatggc gtgatgtatg ctttcaatat ttctacaatg
    12061 aatggtgttt ttttgccata tgaaatcgca ttttcaccgt aattttctct tgaacgttcg
    12121 atttgttctt ctgtcaatcc atttgctgat gcatggaata gttcaaataa ttcttgtttc
    12181 gtttttccag caaaagctgc atagattttt tgtgtatctt tctttttttc catctcaatc
    12241 tctcctttgt gtccaaaaga cagctgttct cgctgctttt ggtctttagc tattcatcgg
    12301 atcgatagag aaaaaactga aaggggctga gaacagatag ataatagccc tggcctttcc
    12361 tctagatcct tgtttttcga atgactgtca tccatttgtt ctcatctcct ttactaagta
    12421 attttaattc atgacttcca atcatttttc gaatagttat ttttccaatt agaccacctc
    12481 ctttttattt ttcaccgatg gggatttgcg gcaacaaaaa aacctctcgc caaatactca
    12541 gcgaaaggtt tgaaaaagca tattaaaaaa agcttctcag atctcatcgt tgagttttga
    12601 cactgtacaa cgtaaaaagc agatacctgc ttttagctac cttatgaaaa gccttatctc
    12661 gacaattcct gttctaccca ttggcgtctc tcgacgtttt tgggcagtag cctatgtttg
    12721 tataggagcc tcacctaaca aatcttattc ggttttcctt cgttaatata acaactaaaa
    12781 aagaggatgt caaatcaatt ttccatgttt ttcatacttt ttttaaaata cacacgttat
    12841 attcctgtct cacgcggttt tatttgtctc attttccacc tcccgctata atagaaatat
    12901 agtaggaaac gaggtgctgt tatggaaaga acacttgtta ttatcaagcc agacggcgtg
    12961 agacgccatt tagtcggaag catcatccaa cgttttgaag caaagggact ggccattgct
    13021 gaaatgaagt ttgaaactat gactcctgaa ttagcaaaag aacattatca gcacttgact
    13081 gagcgcagtt tttttgatga actgatcgat tacatgactt ccggtcctgt cgtttatctt
    13141 gtgctggtcg gcgaggaagt gatcgatatc gtccgtaaga tggttggagc aacaaaagct
    13201 gccgatgctg ttccaggtac gatccgagga gactacgcgc tgccggggac tgaaaacatc
    13261 attcacgctt ctgattcccg tgatgctgcg gtaaaagaga tcgcccgctt tttcccgcca
    13321 ttcgatataa acaaaccgtc tgaaaaagcg gcgaagtgat acaaattcta aactgctggt
    13381 ctagttgctg ggttcagcaa tggccagcag ttttttctct aaggacctcc gttgattctt
    13441 tcctaacata tattcgagca ctgtgaagaa ttcttggtag tctttcgtct tttcttcccc
    13501 taaagcagca gaaatcaatc tttgataata atctgccatc aatgtttcat agatcactgt
    13561 acttctttct ttatgtgcta agctccgttt catatcttca ttcacactac gtgccttttt
    13621 caaccgacca ttttctatat aaaacgaagt caggttcatt aaaaaagtaa agagatactg
    13681 ctcatgattg ttcaactgtg ctaatcgtcg cattcttttt ttgattttca aataattgtt
    13741 ctcaatgaac cgatcactga atatccaagg aaaatcagct agaatagata gttcaaattg
    13801 accatagtct ggtatctgca tcaagtattc ttcaatgatt cggcattcat aacgtaaaaa
    13861 ttcaaattct gtctcagata cttctgtttt ttcgaccatg tgaagattca aaaccaaata
    13921 atacagatct tctgttttct taaaatgcct acggttattg ctgatctctt tataaggatc
    13981 aaagctgtct tcttgtaccc gatctagcat tcgtcttttt ttctttaact ttattggttc
    14041 atccagctgg tttcgcatcc attcatattc tgcaagtgtc atgttcattc gctctaaaaa
    14101 tgatctcaat gttacaaatg acattttttt cactgaattt gtctcaatcc cgactagaga
    14161 agtcttaaaa cagattcctt ccgctaattg ggactgtgtc aacttcttgt tgactcgaag
    14221 tttcttgatc aattcaccat catacataat agttctcctt tttaatttaa atttttccac
    14281 attcaataaa tagatacgtt aaaaaggaaa aatacacgaa aaaaataaaa aaatgttttt
    14341 ttcataaaaa ataccaacct tcaagcatta gaatgttgtc taactactga aggttggttt
    14401 gattgtttat tgattatttt tttgctgttc aacgtctgtt cttgttactg gatataagtt
    14461 ggttgttgtt ttattaccat tttttgaaaa gacacttgtc gaatgttcgc ctttttgctt
    14521 ttcgattgct tcattacgtt ccgcttcatt tttatagtca tattttttcg gatcaatcgt
    14581 ctcaaatccg tttggcacat aaaaccgcaa gagattttcc tgattcagct tatctgaaag
    14641 acttaacgca gtcttgactt tttcctgatc tttggagatt tcctcatcga ttcctgctgc
    14701 tttcgtatcg atgatttctc ctgtctgatt attgtaagct tttcctccta ggacggtgta
    14761 tttgggtgtc acaaagttcc catttcgaaa agcaactact tgatcatgct gagaagataa
    14821 taagtctgta ccaaaatgaa gataatcttt atcatcgatt cccaatagat gtagtaatgt
    14881 cggcaaaaca tcgatttctc caccgtattc atgattgact gtccctttag tataaccagg
    14941 catatggatc atcaatggca ctcgttgcat ctgtgcgttg tcaaattcat cccatgtatc
    15001 tggatcttta ccaagagcgc ttgctaaatc tttattatct gtattcgaga tcccaaaatg
    15061 atccccgtaa atcacaaaga ttgaattttg gtaaatacca gattttttca aatacgtaaa
    15121 aaattgttcc aatgattgat ccagataatg tgccgttcga acataattat ctactgtgct
    15181 attgccagta ttcaaagatg gaaagtcgaa attcttgtca tccgtataat aaggcgtgtg
    15241 gttggttacg gaaagaaatt tcgtgtaaaa cggctgttgt agatgctcaa gatattgggc
    15301 agattctctg aataaatctt tatctaatat cccataacct aacgtttcgt cggattcatc
    15361 aaaataagat cgatcaaaga aattgtcata acctaagttt ttatatacat gatctctatt
    15421 ccaaaaacta gctacattcc catggaaaac agcgcttgta tagccttgct tttgtccaag
    15481 gatcgctggt gcggcttgaa agacattgtc tgacccaagt tctgtgaata atgagccttg
    15541 aggtaaacca aatgtgccag tttccaacat attttcagca tcacttgtct ttccctgtcc
    15601 tacttcatga aagaaattgt caaagctgat cgttgcttga ttctggaaaa tactatttaa
    15661 aaacggtgtg acttcttgtc cgtctacctt catattaatc aaaaactgct ggaaactttc
    15721 taaatggaga acgatcacat ttttcccttt agcgatccca aatgtttcgg gatttggctc
    15781 tgcataatgt ttctttgtat aatctaaaac ttcatcaatc ccattactgc ttgcatgcgc
    15841 gcgaacactg ctagtcattc ctgttttgat tccgtcataa atagtatacg catcgattcc
    15901 tagatatttg acaatatatg aacggtcaaa tgttcgctgc agcaattgtg gacggttggc
    15961 ttcgctcagc gctagatttc ctgaaaaaat aagccctgaa agacaggtaa cagcgatagc
    16021 catcggtttg ccgacagggt tgcttttgat aggtattttc ttgaccttca accaaaccag
    16081 tagcccaatg aacacagcga tatccagcca gtagatgaca tcatggggct tcatcaaaga
    16141 aaaggagctt cctgacaatc cttgcgacac tttcgaaaag cctaatacag atttgactgt
    16201 aatgaaatct gtgaattccc gataaaaaat aatattcaag tacaacaaaa gcgtatttaa
    16261 aatatcaatg atcaaaagaa tagctaacgc tggctttggc tttttaatat acaaagaaag
    16321 gccaaaaaac aataaggtag tcgcaattgg gttgatccac aagataaagt actggatcgt
    16381 accttccaca cctaatgaaa aatctgcata gtaggcaatg atcgtcttca gccagaaaaa
    16441 gaaaacagct gtcaaaacga ttgctaaacg attttggcac aattttttaa gttgtgtcac
    16501 gtatatcact tctctctatt cacatttttt cttattttgc tcctgaaaaa tgaaaatttc
    16561 ctaaaaaagt tgttatctta agattttttt attctttcta aagattattc cgtccacttt
    16621 tcacagcata aaaccgctgc gatgtaagcg attaaactaa tgaagagata aaagtcttgt
    16681 ggtgaccgct tcactccacg gtattcaaaa gccagtttct cggtattcgt acaaaaaaag
    16741 aggctgtgac aaaattcttg tcgcagctcc ttatttcttg atgcaggaca gctttttcac
    16801 aacttcttcc ttaaacggtg ttctcctgcc aactcctcgg ccacaagtca caatatttat
    16861 aaaacatgag aagctgtttt ttgaaattgt tccttgtggc tcagagttaa acggcaggct
    16921 caagacctct tgatacacgg tgttcaatca gctgaccctc ggtattagat tatgtcagga
    16981 cgctaatttt acaacctctt ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    17041 ccaaccaaac gaaaaatata aggagctatt ttttgaaatt gctccttgtg gctcagagtt
    17101 aaacggcagg ctcaagacct cttgatacac ggtgttcaat cagctgacct tcggtattag
    17161 ctcaaaaaac ggcaaaatat gaggaactat tttgccgttt gtttctctaa tactcaggtc
    17221 aaaacgctga tttcacaacc tctgtttttc attgtccata ggattgatat tgtccttgtg
    17281 atgactcatt cgtaataatt gaggcttgat tttcttcact tcccgttatc gtttgtccac
    17341 tgccagaatc tgaaggactt gttcctgtcg actcgttttt ttgagaagag acagttgttt
    17401 tcttgacttg ttcatttgtc tttttccatt ccgctaaacg atcggcgacc acttttttgt
    17461 ctactttttc agaataagcg gtgatcactt ttccattttt caaacgggct actttgtcgc
    17521 catcatgagt caaaagcaaa acggtcaaat gcttgtcttt aaattgatat tgtctgagag
    17581 aaatcgcact aagtacgtca tcgatattaa taaattgatt ttcttctttt ccttttggca
    17641 aataaatgtc caattcgcct ttttcgtaat tggcagttat tttatactcc gcccaccaat
    17701 aagttgagaa ttcttttttg aaattatcta ctgattcttt gcttgctacg attttttctg
    17761 tttctttctg agcaagatct gctgtcattt ttcctgaaaa tgctgcggat aaaataagca
    17821 gtaagaaaaa accgaataac caaaagagaa gaaacggtct ttttttcctc atgctttcct
    17881 ccactcctat ttaattttga ctattctatt atatacaaaa aatgaaatag aaagacaaaa
    17941 aagttgaaaa agatcgtaaa taattgaact tctttttcac aaaatggtaa gaatggagaa
    18001 tttcacgcat ttgctctcaa ctattctttc ttaagcctca aatccgtttt tatctgatac
    18061 gtctttgaac caatgacccg attttttgat tgttcttttt ccatcttgtg ctaagtctac
    18121 tgaaataaag ccatatcgat tcttatatgc attggtccac gaccagttat ccatacatgt
    18181 ccacatatga tagcctaaac aattggcacc ttcttgaatg gcttgatgga catatttcag
    18241 atgagattgg acaaattcga tccgataatc atcgtggatc atgccatctt ctttgataaa
    18301 tcgtgcttcg ttttctacac ccataccgtt ttcagaaata aagcagtcga tatttccata
    18361 atgatctcgt acattgatca aaatatcata gattccttgt tcatagatct cccatccgcg
    18421 ataaggattc attttacgac caggcatttc ataattgtcg aaataatcct caggcattgg
    18481 accgttttta gtatcgattg gtgtttcttt tgcttttacc cggcgtggct ggtaataatt
    18541 gatacctaaa agatctactg tattttcttt gataaccgtc aaatcctctg catggatcac
    18601 aggcatgaga tcaagttctt ttactatctc aatcaattca cttggaaact cgccttttac
    18661 agctggatca aggaatgaac gattgaagaa cgcatctgct atttgcgctg ctttaacatc
    18721 ttcagggttt gattcgtctc ttggatagct tggtgtcaga ttcaagatga taccaataac
    18781 accaccttgc tccatttcat ggtaagattt gatggctaac gctgaagcca acgcttcatg
    18841 atagccaact tggatcgctt ttttcatatc tgactcttct ggataatgcc atcgatataa
    18901 ataacctgct tcgactggaa cgattggttc attatgagta aaccattttt ttactttcga
    18961 accaaacaat tcaaaacaac ttttggcata tttttcatag gcttcaaccg tttctcggtt
    19021 caaccatccg cctttttctt gcagatacat cggcatatcg aaatgataca gattcacaaa
    19081 gggttcgata ccgttttcaa tcaactcatc aaaataacga tgatagaaac gaacggcttc
    19141 ttcgttgatt gttccagatt catcaggtat caaacggctc cattggatag atgttcgaaa
    19201 tgaattatgc ccagtctgtt tcatcaactg tacatcctct tgatacttcg tataaacttg
    19261 cgaggttttt tcaggtccta cttgatcaaa gaacttttgc ggttcttttt tgtaccaata
    19321 atcaaaaatg ttctctcctt ttccatcgcc tgaaatcctt ccttctgttt gtgggccact
    19381 tgctgcagaa ccccaccaaa aatttgctgg aaattgatat tttttcatca aagcacctct
    19441 ttttcttttt tagttcgttt tagttgattc catgtatgat attttccatc acaatcactt
    19501 tttcattttc ttcctcttct tttttgattc gttttaacag ctgttctgct gctcgttccc
    19561 cgattttatc tgttggtggc gtgatcgtga ttttcggaag gatactcaga tcgtttttat
    19621 ctaaataatc atagtgactg aacgcaatat ccttcccgat tctgacacct tcttgattga
    19681 aacattcgat ggcaccaatc gacatattgt aattgctgac aaaaatagca gttgcccctt
    19741 tttctaataa tgcttttgcc ccgtaatagc cgctttttct agaatagtct cctgtaaaga
    19801 cctctaattg gatcgatgga tcattttgga ccgcttcttt ggctcctgct aaacgttctc
    19861 ttgctacgta gtctgtttga gtggcagcaa taaatccgat ttttttatgt ccttgttcac
    19921 catgatgagc gatcactttt gctacacttt ctcgatcatt cactaatatt gtatcaatac
    19981 ctgctggtcc ttctggacaa ttcaatgcga taactggaat actcattttt gtgagcattt
    20041 caaatccaga ccactcttct tcggataaga agacaatcag cccatcgatc acatgcttca
    20101 tcaggtattc aattttttgt tcaatttttt ctggctgatc ggcaaacccg cttaataata
    20161 agctataccc attttcttca gctactcttt cgatccctga gacaacttcc gacccaaaac
    20221 ggctggaaat cccgtttatc aaaagtccaa tagagaagct tcgattattc ttcaaccctt
    20281 tagcaatgat gttttcttta tagtccaacg ctgaaatcgc ttctgctatt tttttcatgt
    20341 tcttttcctt cagttgctga ccattcaagt aacgggaaac tgttcccact gaaacaccag
    20401 ccatcttagc cacatcacgg atcgatgcca tacattctca ctcctgccag ttacatttga
    20461 tttctctttc ttgttgttcg attatgatga ccgcattctt tgcatagtgt tgcttgtcat
    20521 caatatccat ataactaaag tcttcagtag agcaacttcc tctcactatt aattatactt
    20581 aaacaagtat ttgaaccggt tcatttttaa tatagcattt ttttaaaaga ttgcaacact
    20641 tttttaaaac gctttctgaa agtggcggat tttttgcctt tttaaaattt tattctaaaa
    20701 tttactctat ttgtgggtgt tttgtgcgtt tttctcttcc atccgtttga agttttacat
    20761 tccaatggta taatttcttt atcctatcaa atgggggaag tattttgaag aaattaatcg
    20821 tactatttat tttgtctgcg ggacttttga cattgactgg ctgtgatttg tttggcggct
    20881 ctgaccaatc ctcggacgaa acaaccgatt cttctgtctt aaaagcggaa aaagcagata
    20941 ccaccaacag tgtatatacg ctaaaagtac gtaaagatat ggatttatcc gcgggacagt
    21001 tgacatttac agataaaaaa atggaatgga cacgcacgta tcagacacaa ggaactgatt
    21061 cttctgaatc atctgaagaa aaaacagtgc tgacagatat caagatcact accaaagatg
    21121 acgaatatat tatttcagga aaagaaaata aaaaagaaac aacagtcata tttacaaaaa
    21181 tcggtaatta ccgtttgaag gatgaggatg gcaacatcta cagtctatag tgccgtctgt
    21241 tggatcttct tttgtttctc cccttctttt ctgctatagt aaagaagcaa gatgattgta
    21301 aaggagacga aatggatgat cgatagtcct gattattgta catgtaataa caacaaaaat
    21361 atccatacag aatttaatga ccaaggaagc ttgagcatat gcgacaactg tcacaaacta
    21421 gtcaaagatt catttaaaac atttgaatct tatcctgttc aaaattatgt aaaaagtaga
    21481 agaagataaa caaatccaag caaaactcac tatggctgat ttttatgaac ttcaaactca
    21541 gcttcttcct ttgatcaagc ttcatcagta aaacaaacag tggatcattt cagtttacaa
    21601 atcaaagagt aaagatttat ttatttcaaa tatttgaata taaaataacc aaacgataga
    21661 aaggcttatt ctacatcacg tagtaatttt tctttcccgt cgtttggttt tttattttta
    21721 gcctaattct tgaccttttg catgctggtt atccgtaaaa tattttccag caggctttcc
    21781 ttccaattca gctaattttt cttggatctg acggatcacc ttttttgcat cttctggatt
    21841 ttctacaaaa tcgaatttat ccccatccac ttgtatttta ggacatacat caaaatcttc
    21901 ataccattga ttatagcggg tgttcaacgt ttcataatag gtatataacg tctcatcgct
    21961 ttctagctgt tcatagtcac gcccacgttt tttgatacgt tctagcatcg tgtccaaaga
    22021 aactttgata tggaccatca aatcaggccg tttttttgga gcaacatcat ctaactcgtt
    22081 tagcatcgta tctaataagc tatcgtactg ctgtacttcg atatccgtta cccgacctaa
    22141 atcagcgttt agatggaaca acaggctatc ttcatagatg gatcggtcta gcacattgtc
    22201 atcgttcact aaagcatttt tcattgctaa aaatcgcttg ttcaaaaaga agatttgcaa
    22261 taaaaaagcg tactgctcag gatttgaata aaagagcggc aatacttcgt tatcttcgac
    22321 attttcataa aatggtttag aatcaatctc ttttgcaagc atatccgtca aactgctctt
    22381 acctgcacca atcgttcctg aaatcaaaat cactgacata caacccttcc tcttctataa
    22441 gtactcgcct acgtaagttt caacaggcaa tgtttcaaaa tcatattcac gtacagcttg
    22501 gtctgatttt aaatacgtat ggagactttg tgtaatcatc aagttcgtag gtaccgtctc
    22561 ttcttgtaca atgatcatcg gttttttcaa catagttgcc acacctaatt cgtaagccgt
    22621 tcctggatcg attgtttgat gctcaaagtc aaggatagca acaacaaatt ctgcatttgt
    22681 cagttcttcc atatcttttt cgtatacttc ctgcgcccat ccagcgctga atagttcata
    22741 attgctttct tggtgatgac gtggagagta gaaacttgtg actgttttgt tttcctccaa
    22801 cgctttttcg atacgactta ctcgatcgat ttgctcctct gaaaaaaatg gtcctgctaa
    22861 atatatttga ctcattattt tgcctccttc aataataact gatttttaat agatactgct
    22921 cgtaattcat tgaccagttc caatggattg ttggaaaaga ttacttgatc caaccatttt
    22981 ttatccataa aatcctcttt tgcaaaagtt tctaataatt gttgcaagcc gctgtaataa
    23041 ccgccaatat tcaatattcc gattggcttg tcgggcgtca gaccgattgc tatccaagaa
    23101 agaagttgtg agaattcctc caatgtacct agacctccag ggaaaacgag gacagcatct
    23161 cccttttcaa ataataatac ctttctttca tcgatcgttt ctgtaggaat aaatgtagta
    23221 acatcttttc caggcaattc agtttcaaaa agcccattcg gatagatacc tgtgactttt
    23281 ccgttatttt ccagtactgt tttactaatc actcccataa tcccggagta tgaaccaccg
    23341 taaaccagtt cgatttcttc ttgtgccatg tattttccta acgtttgcgc aataaatttg
    23401 taactttctt tattaccaaa acgggaaccg caaaaaacag taagtttcat aaaaaaacac
    23461 tccctaactc aaaagtctat cttcattcta cacgtgtttt tttaaaataa aagactagat
    23521 tttgtagttt tttagtggta tataggatag acgccactat atatagtatt tagaaaaaaa
    23581 tcatttttca gccattttat agataaaaca aaaataaata acgtgttctc atcgatatga
    23641 aatgacttac ttatagaaga tactgggatt tcgtcctata tgccaataac gtgtattatt
    23701 ttaaacaaca aatacttgtt tcttttatta acgaaaaaat cattttgttc tcgtgttatg
    23761 tttcactgat aaatgatgtt tctctaaata aaaaagccga cgaactaaac gatcaaaatt
    23821 tgatcatttt tgttcatcag cttctcctaa aaatcttttt gttaacgata aatagctgga
    23881 tttgtaaaaa tatcacttga atcgtcactg ctggaagaaa attcagtgat aaccgcacct
    23941 gttgcgcctg cctggaacta gtgtttgata ttgggctcga acgtgtactg atctctagca
    24001 tgaagaataa tttctttttt tactgtataa taactttctt tcctttttgg aatagtacag
    24061 gaaagttttt ttgtttcctt tccttcgaca taaggtatac cagacccttt cgacaacgaa
    24121 aggttctcat ttttccttca tcgtcatttc aaggagggtg ccgatgctct ggacagtttc
    24181 gatcgctcct aaaccaaaat ctgtatattc gattctttct aactctgatt ctttcatacc
    24241 attcctgtct caaggtacat ctattgtact tttttcttgt aatccattct gcctctccta
    24301 actaattgtc aaatcatccc aagatatgtc ttcttcctct ttttcttctt ggatgatttc
    24361 tgcattcgga tctactggtt ttttcaataa taaaatggtt attcctgtga caaaagaacc
    24421 agctaacaat gcaccaatga atgcccatgg tctggtcatc gtagcgactg caaacattcc
    24481 cgatgccgga atacggctat ctgcgcccca aaacatgctt aatccgccac ctactgtccc
    24541 accgactccc gttgctatga cattgcgtgc caagtcgttc aatacgatag ggaaacatcc
    24601 ctctgtgatc tgacagatcc ccataggaaa agcggtcttc aatgtatcga tttcttgacg
    24661 attgagtata tttttacgaa tgattttccc taagaaataa gcgatcgtca agccgaatgg
    24721 ggttaccatc gaagctaaaa tcaatacagt gattggttca tagattcctt ctgaaaatcg
    24781 tgccacaccc ccttatccag aataaatggt aatccagaaa cagccgtgta tctgcggtaa
    24841 taagcctaac caaacgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
    24901 atgcagggca gctttttcac aacctctttt tttatttatg tttcataatc aatatggtaa
    24961 ggatgcagct ccgtatggta gaccgcctcc gaatattcaa tcatttcccc aatttgcgta
    25021 gacgatttcc gtatccgttt gatgccgatc tgtgcgtctg ttttcagaat tccttgttct
    25081 tcttctgtta aaaatactgc cgagaaatca tcagaaaatg agtcaatagt atatcctttt
    25141 ttcgtcagca aacgatacaa agattctttg ccaaattctt ctctgctgaa ttgcatcatt
    25201 tcttgtggaa gataatgaac aaaataaata taaggctgat tgttcaaata atataagcgc
    25261 ttaaaacaaa cagcttgctc accgaaaaag gaaaacaaag gatcttcctt ctttatatgg
    25321 accaattgca aatccagcgt ttctttccgg acttcatatc gggagttctc caagatttgc
    25381 gtaaagcttg ccgctttgga taatcgattg taaggacgat tgcttagaac cgtcgtccca
    25441 cgaccacttt tctttgcgac atattcatct gatgccagca gttcgattgc ctttcggaca
    25501 gtgattttgc tgacttgaaa cagttcttct aattcacttt ctgtcggcaa catcgaaccg
    25561 actggatatt ttcctgagaa aatatcttct ttaattttat ctgcgacttc caagtatagt
    25621 acacgtgtcc ttttcataac gtcacccttt gctttactat tactaaaaga atagcacata
    25681 aaaaataaaa aaagaacaca aatcacatgt gagaagtgtg ttctttttca ttcagctgct
    25741 ttaattacaa gtttacgcca tttgaggcaa ttacttcttt ataccaatca aaagattttt
    25801 tctttgatcg attcagtgtc ccatttcctt catcgtctag atccacatag ataaagccgt
    25861 aacgtttact catttctcct gttgatgcac tgacaagatc gatacatccc caaggcgtat
    25921 agcccatcaa atctacaccg tctgctactg cattagccat cgcttcgata tgacgacgta
    25981 aataatcgat ccgataatca tcaataatcg tgccatcctc ttccatatga tcaatggctc
    26041 caagaccgtt ttcaacaatg aataatggtt tctggtaacg attgtataat tcattcaatg
    26101 cgattctcag cccttctgga tcgatctgcc agccccattc acttgcctca agaaacggat
    26161 tttttactcc tcccagcaag ttcccttctg aagttgctgc ttgtggatca gtctcattga
    26221 ttgccgtaga catataataa ctaaatccga tgtagtccac tggatattct tttagcaact
    26281 ggaagtcttt ttccgtttgc tctaattttt ccggatcgac tccatatttt ttatgggtac
    26341 gcgctgtgta tgcagggtat tctccacgta cttggacatc cgtgcagaaa aaattgaatt
    26401 cttggttttg gatcattgtt gctgcctgat tgactggatt ggcatcgatg ctgtaagttg
    26461 ttgcatagat aatcatgcag ccgatttgga tatccgaacg caattcgtgg ccgattttta
    26521 cggctttgct acttgcaacg aattgattat gccatgcttg gaaaatattt tggtactctc
    26581 ctgctccatt gctttttact aatccttgac ttaaagctgg aaagtgaaag gccgaattga
    26641 tttcattgaa agtcatccaa tatttgactt tactgctgta tctctctaat actgtctgag
    26701 caaatcgttc atagaagtcg atcagttttc gatttttcca gccaccgtat tcttttgcca
    26761 aatgaagagg catttcgtaa tgagaaatcg tgatcacagg ttcaatatca tattttaagc
    26821 actcatcaat cagctgatca taaaattcta atcccgcttc gttaggagta ccttcgtctc
    26881 catttggaaa aattcgtgtc caggcaatcg aaaaacgata acatttgaat cccatttccg
    26941 caaacaaggc aagatcttct ttgaaacgat cgtaatgatc gattcctcga tgattcgggt
    27001 aaatatattt ttcttgatca atcgtccagt caaattcttc actgccgata atcgcaaagc
    27061 gctgcttacc tccaggcata gcatctgcaa cggatagtcc ttttccgtct cgatcataag
    27121 ccccttctaa ttgatttggc agcagttgct ccaccccata aaaatttttc tgaaaaacgt
    27181 gattgcatcc tgatttcctc cttattttac aattgccaga acatcttcgt ttgcaataat
    27241 ctctttttgg tctaattcaa gtatatcggc aaatgcatca gtattcgtaa tgacaactgg
    27301 agtgattacg ctatagccag ctgctctaat tgcttcgatg tcaaaacgaa tcaataaatc
    27361 tcctgctttg acgagatccc cttgtttgac taagatctca aagccattcc catttaattc
    27421 tactgtatcc atcccgatat gaatcaaaat ctccgctccg tcagtcgttg tgatccctac
    27481 agcatgtcca gttggaaaaa tagtcgtgat ctctccgtct gcaggtgcaa ctagttctcc
    27541 tacttctgga tcaatagcga taccttttcc catcacgcca gaagaaaaaa cttggtctgg
    27601 tacttcactc aatggcagta ctttacccgt taaaggactt tttaaggtat gccgtgctga
    27661 agtaatcggt tctcctgcat tcgcatgttt gttttctaat tgattgtctt gtgtttgttc
    27721 gtcaaatcct aaaatcaatg tacctacgaa tgcaagaaca aaagcaattc ctgtagctat
    27781 tactgctact gtcacatttg actctacacc atccaccgta ttaatgaaag tcggaatcgt
    27841 caataagctg accaaactgc tggagaaagc ttttactccg gaaaatccga taatagctcc
    27901 accaatacct ccagaaatac aagcggcaat gaatggtttc ttcaaaggta atgtcacacc
    27961 atacacagtt ggttcagtga ttccaaataa cgaagtcact gtagaagaaa tccctaatgc
    28021 tcgaagtttc gtatcttttg ttcgcaatgc tacagctaaa gcagccccac cttgtgccaa
    28081 gatggctgga agaagcattg gcatcaatac atcaaaccca tattgttcga tattcaaaaa
    28141 catgatcggt acgaatcccc aatgcatgcc gaacatcacg aatacttgcc ataaacttcc
    28201 catgattaga cctgctacga ttggactaaa tccataaatc gagttgaaga gaccgcctaa
    28261 agcattaccg gcaaccgtcc cgattggtcc taaagcaaga aatgttaatg gaaccatcac
    28321 tactaaaacg acaagcggaa ctaaaatcat ttgcagaaat tgcggaatca ctttttttac
    28381 gaatggctct aatttacttt gaacccatac ggctagaatg attggtatga cagaagaagt
    28441 ataaccagat ggtgaaagaa tcactgggat cccaaagaaa ctgatagctt ctcccgcacc
    28501 agcaactgct gtgatagctg gatacacaag tgccatagca attgctactg ctaaaaactg
    28561 gttggctttg aactttttag ctgctgtaaa agcaagcatg acaggtaaga aggtaaagac
    28621 accatctgct gcagcaaaca atatttgata agtaccgcta tcagctgtca gccagcccat
    28681 caccgttgcc aatgataaga atcctttcaa taccccggcg gctgccatcg cccctagaaa
    28741 aggtgtaaat atactagaga taatatcgat cagacgattc aaaatatttt tggactcttc
    28801 ttttccatcc tccgaaactg caagaccttc ctcatccacg atcgattgat aaacatctgc
    28861 tacattactg ccaatcacta cttgatactg accgccactt tgtacgactt ggatcacgtc
    28921 cgggtcttct tttaactttt gcgtatctgc taaagattca tcttttaatc tgaatcgcaa
    28981 ccgcgtagca caatgtacta aacttttgac attcttttgt cctcctaccg cttcccatac
    29041 acgacgacca actgcttgat tatccattgt tttttccttc tttctttttt atttaaaaaa
    29101 taaaaaccca gattgaaaaa aacagtcaca aacattcgtg aacctatttt ttcaatccag
    29161 gttttgcctg ccatacagta acaatcctta tgattggatg ctttttttct cacttactac
    29221 tctttgaata tgaatcgtta aataaatctg ctctgcgatc cccatttcct gtttttgcgt
    29281 ttgtcgaaga tactcattga tccgttcgac acaatgaaac gcttttggat actttccttg
    29341 aactaatgcg tagagaaatt catcttgctc gtcagatcct tcccctttga gataacgctg
    29401 ggcaaaaaac tgcagatgag taatgatacg ctgataattc aaagattctt catcgaacac
    29461 gatgccgaag aatttactga tgatactcag tatatctctt accattgtgg tagcggtcat
    29521 cgtcacttgc atgtcttcgt ttccttgttg gctattcaca aaatgaaagg caataaaacc
    29581 ggcttcatcc tcagaaagtt ccacacccgt cttttgtttc acgaacaaaa gagcctcttt
    29641 cgctgcttga tattctttcg gataaaattt ttttgtttca aataataatg gattaggcag
    29701 ttggatattt tcttttgctc gtgtgatcgc ataatgaaga tgatcggtca atgtcagata
    29761 aatattaggc gaaaattcaa cttttagttt atcttcagcc agttcgacta cttgtttgac
    29821 ccattcgatc tcctctgccg gaatatcagc catcagctgc tggaattggt ttttagcaaa
    29881 agaatctctt aaaacaaatt ctttttggac cgcttctggc gaaatctcgt ccccaatctt
    29941 tttttgaaaa gctagtcctt ttcccataca aacgacttct tccccgaatc catttttcga
    30001 aatgacgaca ttgttattca aaattttatc aattttcatt ttgcttcgcc ctctcaagaa
    30061 aaataaaaaa acctagaatt cgcctactgt ttcttagctg aattctggtt ttgcctgccg
    30121 tacagtaaca atccatttct tattcaaaat catcatacca tcgaattttt atttatgcaa
    30181 accttttcat ataaaaaata aaaaaactgg aacacaagtc tatctagaaa acaaccaaat
    30241 cagagatgca cctctttgcg tttctctttt tttcagcaaa ttggtttttc cttatcgatt
    30301 catatccttt ggctgttttt aatctgtaac gacttatgtc ccagtatcct aaaatgtttt
    30361 tgtctctaga ttgaaagcag atctcatatc atctgtcgca tcttttatcg atgtaacact
    30421 ttccagttct ccttgtacaa ctagtcgcgt gacggcgtcc atgtcgccac aagtaattag
    30481 tgtgacaatt tcttttccct cgacttcatt cagtaattgg gtatctgtag gagcaacttt
    30541 ttctttaaaa aatgttttgt atgtatacac attttctaaa tctgtcaaat agatcttggc
    30601 acccatctct aaattttcta gcggtgtaaa cagcaattca gggttcgttg cacgatggct
    30661 tgctaaggca taatttcctt ttcccatttc ttgatctgga gataatgttc ctgctccgta
    30721 aagtagtgac gtattatcca agcctttgaa aaccggtaaa ttgattgaaa ctgaagggac
    30781 tgcgatacta gcaatcactg gtagatctgt tcctctcatt tgcgacctca tgaccccttc
    30841 tgtcgtcatt ggttctaccg catcaaagtc aaaactgaca tctttatcgt tattcttttt
    30901 cagatcttct tttgttacat tcgctatagc atatttatct cctgtctctc tgacaaaata
    30961 atccttgatc tgttcattga aaatcaaagc tagtcctact aataacaaga ggaacaagag
    31021 gatattgact agccatcttt ttgcttttcc tttttttttc attttctctc cctccagact
    31081 cattttactg tttttctttt gctctttcca acagccgaat gacacatttc tacaactctg
    31141 tgtatttttt tcgtacacct gcgctttttt ctacaggata tttcaaatta tttttgatca
    31201 atttttcttc aatgatctca tctagatcca ggtgaaggtt gtctgccatc atgtatgaat
    31261 agatcaatac atctgccagt tcttctttga ttcgttctaa ttgtgtttct tttacttctt
    31321 ccggcgtttt ccattgaaaa agttctaaca attcagatgc ttccaaagaa atagagatag
    31381 ccaaatcttt ttcgttatga aattgtcgcc aattacgttc atctctaaac tggttgactt
    31441 tttccatact attcatttgc ttgccttctt ccaatcactt cttacttgat taatcatacc
    31501 atttttttac ataaaaaata gatgatgctt ttaaaaaaac tcctgttttc ttttatttaa
    31561 aataaatgtc atagaaaatc aataatttag gtagccacca tgtgtatgca gtagcgtgtc
    31621 ttcttccctt gaggcttttt gtttttcgat acgttcttct tcccaaacag acaacgctac
    31681 tagaatctct cttaatgatt ttccttcttc ggtgagcgag tactctactt taggcgggac
    31741 ttggttatag gcttttcgat ggatactttc atcttgttct aactctctta actgctgggt
    31801 cagcattttt tttgtgatcg tagggatttg cttgcttctc cacgcctaaa ataagcgata
    31861 ttgctcttcc ctttatctgg tgtaagcaaa gcagttagca ttttgacgat cgtgggttcc
    31921 gcttttcact tcttatctac ttagtatcat gaagtatact ttcgtactaa tactaagtag
    31981 cggaagtgtc aactactttg tttaactaca tagcaaaaga aacagaaggg tgacaacggt
    32041 catcacgctt ctgtttcttt tgaatatgct gtgttgttgt ctctatctcc gtgtagactt
    32101 tcctcaaact tatcctttga cagtaagtca gtaggctgat ttgctctttc tagatgccag
    32161 atacatttct acaaaaaaat agtgattctg ttttgaaaat tcgattttta gttctgcatt
    32221 ttcgtaaaca tccaacattt ttttcgcact gtatagacct aacccgccat tttttttaga
    32281 ggtttttcct cttttgacca tctccgatag cgtcaaattc gttggatttg ccttgttcgc
    32341 tatactaaaa cgtgatccct ctttttcttc cagcagattg atcgtaatcg gactctgatc
    32401 ggctacacga tgatcgaatg cgttagaaat aaaaatagat aaacagcgaa taaaaacaac
    32461 cagatcaatc gggattgttt tcacttcgac aggaataact acttggatcg ggattttctc
    32521 cgattctgct ttttctagaa attttaaaaa gacacccctg acagctgggg atacaatatt
    32581 tgttagctgt tgtatttgcg gtttttcaaa aatagctgca gaatgatctt ctaatatttc
    32641 taaaaattcc aacgtttctt ttttattttc ctgaagagta atttttaatg aaaacagtag
    32701 acttttataa tcatgtttga attcctctag atgatggtaa tattcttcat ttatttgata
    32761 cagttgaagc gattcctgat gttgtctttc ttttacttgg aaactgatca acataatgga
    32821 aaaaaacaaa gaaaaaaaac tgatgactat cgacaaaaga gatagaagca gataattaga
    32881 tgagcggaag tgaacacttc ccaataccaa gtaaatcacg ccccagctta ataaaataca
    32941 aatacctcca aaatagtgtt cagttggata agtaaaaagc aagttgagaa atctcgtctg
    33001 tttgtctata ctttttacta atagatagaa aataaatgcg ataagtagtg caaaaaaact
    33061 tgctgttcca agatgtctct ttcctaaata atccatcaga tcaaaaacca gaaaaaagct
    33121 gagtccagtg atagcaaaaa aaagattact gatcaaacag ctgataaaca ggtttttcgt
    33181 agtaaaataa aaaagaaaca tcaataataa gccaactagg taaggaaagc tcactttagg
    33241 gataggaagt aaaagtgtca ccaccatcaa agctatacaa ccaaagctgt tttttactag
    33301 cagttgtttc gaaaagaata aatagatacc taaatctaaa atcaaagtaa aggtcaaata
    33361 aagtgtcact gttgcgacca tcttattcct ccattgtttt gtttcaaaat gtacacatat
    33421 ttttttaata ggatcctgca tatgaaaaag tattttatca tagaagataa ccagtttcac
    33481 agcgaatgga tcatcagaga attggtcaat catcatatcg agaatatcgt gcagctcact
    33541 tctatctctc aaatcaatca gttgatccag ttgggcacta ttgataatca cgatgttttc
    33601 tttatcgata tcgacttgaa gcaatcactc acaggtattg atgtcgccga acaaatacgt
    33661 aaaaaaaatg cacatagtaa tattgttttt ttcaccgctt atacgaattt tgcagtagag
    33721 atcatcaatc ggaaaatcct tccgattgga tatatcagaa aagacaggaa tttatctgaa
    33781 caaattcgtc aagtgctaga acagatcaat tggaaagaac agcagatcgt aaatgtcgat
    33841 aaaatcttta ttgatcaaaa aggtggaagt ctcgtcctgt atcctcggga aattttatat
    33901 attgaaagta tcaaaggttt gaaaaaccaa gttatggtca aaacaactac agaagataaa
    33961 ttagtgaata cttctttaaa acaattgaag acagagttag aaaagtatgc ttacttttta
    34021 cttttaaaat cttactgtat caacttatcg caattgcaga aaattgattc tgctcattat
    34081 gtgttagaat ttttcaacgg tgactcctta ctcgttggtc gaaagatctt tgaaaagaca
    34141 aaggaacgtt tccatgactt ccaaaaaact gcttcgagtt gatgaataag agctgagacg
    34201 taagcatagc agatttcagg gagtgggcct tgaatcggct ccactccctg aaatcgttga
    34261 tatgatttta cgcttcctct tctgtaggag catctgttaa cgaccatgtg aatgttgaaa
    34321 cgtagttgtc tacagcataa ttggatacag gaacaaataa ttccactgat tgtctccctt
    34381 gttccacatt ctctcctaat gaataaatcc atgtgccaat cccttcattt gctcctgcag
    34441 ttactagatc tactgcctga tctgctggga tttcgattcc ttcagcgcca gttccagaaa
    34501 cggtagatgg cattccactg ctattagttg cgctatttcg aatcacggcg tttttgaatt
    34561 tcacctttga accagttagt ttattcgtat cagatgttgt accaataaat tctgttcgtt
    34621 tgactgataa tttccaaccg gcataatttc cgcttttatc cgttacttgt acgaaattct
    34681 gtacttgtgt ttgtgctcca gtactgtccg ttccgctttg taatgcagca tatactgttt
    34741 ttgctgtacc taacttgatt gttccaaaat caagatctgg agcttggtca atcgtcagta
    34801 atccggatgt tccctgattt ggttcgtcag gtgtaaaagg agtatcagga tcatttggat
    34861 caacaggagg aactggaaca acgtcttcag gatttgcagc atctggtttg gtcacagaaa
    34921 tcgttccttc tgtagtggct gagctcttat tctcagcaaa aacactttgt gtacataata
    34981 atagacttcc agctagaacg gtacttaatg caattgtttt tttcatttct ttttccttct
    35041 ttcttttaaa ataaataatc cagcaaataa gccaataaga atgactccaa caagtatcag
    35101 ccatcgccag tcaaatgttt ctggctgatt ttttaaatca atatcctttt cattcaattg
    35161 gtccgctgca tcatcagtta tttcaaaatc ggtatggaga ttccagcgtt tttctttcca
    35221 agcacccttc acaaccgctt gataatgtcc cggagctaat ttttttcctt ctaatgggac
    35281 aagtaaatca aaatttgtat tgggtgctac atctattttt tcttttttta ttgaaaggta
    35341 aggctctttt gtttcttttt tgtagatttc aaccgatgta gtcaagccga acatataaga
    35401 agcatttgga ttttgaagat tcgccttaat cacatttctt ccatcgcttt gatccgcata
    35461 agcttttttt aatttcaaat ctggggaaga ctctttttcg ctatttcaaa tcaagattgc
    35521 tttcacttga gaaaactgat tgacgacacc aactgtactt ttgttagaaa cgttctcttt
    35581 tttttcttga aacgtgatcc ctcctgcgac cacaccagcc agctcttttt ctggcgcttt
    35641 cagtgaaagt gtctcagtga ccgcactttg aggaggaaca gttatttctc ccactgtttt
    35701 tgctaagttt ttcatatcat aacttaatgt ttcatcaaat ttactttttg attctccata
    35761 ttcgatcaca ccgtttgaat tcgtcgtagc ggagtggatc aatgtctcaa ctgttactga
    35821 tttatctgtt cggttaaaga ccgtgtaggg gatttcctgt gttttcccag gctccatcct
    35881 tacatttata tatgttttgt tcttatcaat ctgattagcc ggtaattcaa aatctaccgc
    35941 aaaattgaat tcggaggcat ggacaggtgt ctgccaaagg atgaatccaa ggagaaggat
    36001 cataagtaaa gagcagttgt ttcgatgact tttattccat attcgattca tcaatcatcc
    36061 tccttgatct ttattctgtc ggcgcatctg ctaatgtcca tgttatctct gctgagtaat
    36121 taccagctat ctgattttct ttggttaaga caagtttaaa cgcccgaccg ttatttaaat
    36181 attctgaata atctgcttgc acattcgttg aattttgtcc tctgacaatt tccagttctt
    36241 cttcattcac taattgatac tcctctcctt tcttgaaata taggacatcc tgcatagaaa
    36301 atcctgcatc atttgtgaaa ggctgagata attttatcgt taagatccac ggatttttcg
    36361 tttctcgctg atcataaatc cataattttt cctgtatatc catttggcca aatgcttctt
    36421 gtgtcaaacc agttgctttg atctgaccaa aatcgagttt ggaaggggca agaaatgaga
    36481 gaccaccttc tactacgatc ttcgtagcag gtgcaaaagg cggggcatca tgataaacaa
    36541 ctggcgtatc acttggattg tgattcccaa tttcatcgtt ggtacttggc ttgttctgca
    36601 cacccttagc agtagcttct cctgcttggt cgtttaatac aatttctaat acatctcctg
    36661 caaaaagttg attttctggg atagaaagaa caaattcccc tgtatcatca atagttgttt
    36721 ctgacaaaac agcttgattt tttttcaatg aaaccaaggc tcctgcttca cctgtacctg
    36781 tgatcgtgcg agaagctgca ttgatcaatg tggtacttaa attagcaggt tcaggaggaa
    36841 tcacatcgac tgtcgttttg gcagagtcca gttctgtcac ttcttggcca cctcttactt
    36901 ttttagcagc aacaacttgc acttgatcct ccgtttttaa tctctcatca ttgggtactt
    36961 gaacttcgaa caagccgcct tgttcgcctt ctccccatgg gttatatcct gccccttcat
    37021 tttcatctgt ttgtccttgc gtgagagcag taatttctac agatgatttc gtcgtatctg
    37081 cgtaagtaat acgtaaagtc acttctactt cgcctgtcca agcatctctt ggctttgcct
    37141 cgacaccttc gggaacaacg acatgcccat agattttttt atctgcattc gttggcactc
    37201 ttaaggattc aatcatcggg agctgattat tggcactgat tcgattataa tttttcattc
    37261 cggcacctgt ctgagcaaat tcatttgtta aacctgcact agggcttgat acgaaattgc
    37321 ctaagtcggt cccattgatc gataagtctg tcatatcaga aaaataatcc gggtcttttt
    37381 caaagttatc gaatgttgcg cctgtttttc gccataaagc gatttctgaa tgggcgatct
    37441 ttaaagaaga atctccattt ccttggaata cccagccgcc tatgccattg gtctcgcttc
    37501 caatccgttt gttttggaaa tcaaaatagg taggagattc taagtccaca ttcaacacat
    37561 ccccactgat gatgccggtc ttatcttccc ctgttttccc gaccatgact aaataagttt
    37621 tttcacctgc cgtaaaattt aaatcaatat ctccagttgt atctacagtt gctccggaat
    37681 ctgcgcgtat atcgatattt gatttttctc cagtgactgt aaaatcagct gaacctggac
    37741 tttctagaaa accagaagcg tcataaaatt ggatcgcttg atttccttga ttgagtctgt
    37801 tcacgtaaga tttgccatca cctgtatttc ttaccctcaa tgagcctcca ttggttactg
    37861 tcagcttttg cgtaccattc tcaaaacgaa ctgcgctgga acgcccactc tgcttatcga
    37921 tgtcgataac tgatccggct ccttctacga tcaaagaaag gccttttcct acaaaacgca
    37981 tcccattgtt cccgggttga tcgtcatctc cagccatttt gaccgagatt tgtccaccac
    38041 ttgatacatg gatttgacta gaatctcctt gcaagcgaaa tccgcccgta gttgctgtat
    38101 tgatggtgat tttcccacca ttcgatacag tgactttcga tcctgaacct ctcatttgga
    38161 tgattccgcg attgttgtca ttggtaatat tgatctttgt atttaccgaa aattcgcttc
    38221 ccgaaccact gacttcaaac atgacattac caggtagcgt atcgactgcc tctccttcat
    38281 cgctaacgcc atctgcccga tcataatcaa gagagacctt tgaaccgctt aagatatgga
    38341 ttcctggcgc tgtttttcca ctaccagtct catctcctga atctagaaaa ccgtagaatt
    38401 tccctagata cggtccataa agttgactac cattgatcac attcaattga tagcttctac
    38461 aaaaataggc tttacccgga gcggcattca gtccttcctt cactggttgg acatccaaca
    38521 caccggaaac accatctaat gtgacagttg cacgaggagc gtaaatcagt cctaatttgg
    38581 acccatcata caaatcaagt gtcccggtaa attttatttc tcccgtaaaa tgatatctgc
    38641 ttccccaaaa atcggtcata taagcaatga taatggcatt tccatcgata tttggtgtca
    38701 atccacctgg atgtgcagct gttcctttaa aattctggaa ctcgatcgac tgaggtatct
    38761 cattgatata aatatggtgt gtgccgaaat tgtgagcgaa tccaccaaaa tcaataacga
    38821 tatctcgttt gatctctaat tccctgtcta aagtcaaagg ctgaatcagt cggatcttag
    38881 ttactgattc gtctgcgaga agctgcgcca gttcttctgt tgtggcagct tcgctgtacc
    38941 catccgctga aacagctctt gccagtgccg cttcactgct atcagacgtt tgttcagcta
    39001 cttctgaggt ctcacttgtc ttattttctt cttgcctttt attagtagaa gcctcacttt
    39061 gagattctgt agtttcagaa gtaatcgatt cttctgaaaa agtagtcttg tcaaaacttt
    39121 gattctctga ttgcgttgat tcgtttgttt tctctacatc ggcaaaaacg gatgtcacca
    39181 tcaagagagg gaagacaaac aaaatcgacg caatcagctt ttttacacat tgattcattc
    39241 tccaccatcc tctctgacgt tttgacaatt ttattttatc gttttaatct atttccaatt
    39301 gtactttcat atttaaaata
//
LOCUS       DADQCX010000016        37970 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.016, whole genome shotgun sequence.
ACCESSION   DADQCX010000016 DADQCX010000000
VERSION     DADQCX010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.016"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            66..767
                     /locus_tag="J8R83_000770"
     CDS             66..767
                     /locus_tag="J8R83_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAZ9573919.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            764..1885
                     /locus_tag="J8R83_000771"
     CDS             764..1885
                     /locus_tag="J8R83_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAZ9573920.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1900..3132
                     /gene="pepT"
                     /locus_tag="J8R83_000772"
     CDS             1900..3132
                     /gene="pepT"
                     /locus_tag="J8R83_000772"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAZ9573921.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3264..4172
                     /locus_tag="J8R83_000773"
     CDS             3264..4172
                     /locus_tag="J8R83_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAZ9573922.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4207..4479
                     /locus_tag="J8R83_000774"
     CDS             4207..4479
                     /locus_tag="J8R83_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAZ9573923.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4490..5536
                     /locus_tag="J8R83_000775"
     CDS             4490..5536
                     /locus_tag="J8R83_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAZ9573924.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5787..8396
                     /gene="clpB"
                     /locus_tag="J8R83_000776"
     CDS             5787..8396
                     /gene="clpB"
                     /locus_tag="J8R83_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAZ9573925.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8547..9218)
                     /locus_tag="J8R83_000777"
     CDS             complement(8547..9218)
                     /locus_tag="J8R83_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573926.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(9211..9705)
                     /locus_tag="J8R83_000778"
     CDS             complement(9211..9705)
                     /locus_tag="J8R83_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAZ9573927.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9725..10945)
                     /locus_tag="J8R83_000779"
     CDS             complement(9725..10945)
                     /locus_tag="J8R83_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9573928.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11092..12927
                     /gene="lepA"
                     /locus_tag="J8R83_000780"
     CDS             11092..12927
                     /gene="lepA"
                     /locus_tag="J8R83_000780"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAZ9573929.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            13123..14034
                     /locus_tag="J8R83_000781"
     CDS             13123..14034
                     /locus_tag="J8R83_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9573930.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            15030..15281
                     /locus_tag="J8R83_000782"
     CDS             15030..15281
                     /locus_tag="J8R83_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573931.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            15364..15636
                     /locus_tag="J8R83_000783"
     CDS             15364..15636
                     /locus_tag="J8R83_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573932.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            15726..15965
                     /locus_tag="J8R83_000784"
     CDS             15726..15965
                     /locus_tag="J8R83_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573933.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            16112..20395
                     /locus_tag="J8R83_000785"
     CDS             16112..20395
                     /locus_tag="J8R83_000785"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAZ9573934.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            20494..20859
                     /locus_tag="J8R83_000786"
     CDS             20494..20859
                     /locus_tag="J8R83_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573935.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            20861..21313
                     /locus_tag="J8R83_000787"
     CDS             20861..21313
                     /locus_tag="J8R83_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573936.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            21927..23237
                     /locus_tag="J8R83_000788"
     CDS             21927..23237
                     /locus_tag="J8R83_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAZ9573937.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            23260..23571
                     /locus_tag="J8R83_000789"
     CDS             23260..23571
                     /locus_tag="J8R83_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573938.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            23932..25188
                     /locus_tag="J8R83_000790"
     CDS             23932..25188
                     /locus_tag="J8R83_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAZ9573939.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            25185..25730
                     /locus_tag="J8R83_000791"
     CDS             25185..25730
                     /locus_tag="J8R83_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573940.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            25731..26231
                     /locus_tag="J8R83_000792"
     CDS             25731..26231
                     /locus_tag="J8R83_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573941.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            26312..26868
                     /locus_tag="J8R83_000793"
                     /pseudo
     CDS             26312..26868
                     /locus_tag="J8R83_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            26888..27232
                     /locus_tag="J8R83_000794"
     CDS             26888..27232
                     /locus_tag="J8R83_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573942.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            27251..28162
                     /locus_tag="J8R83_000795"
     CDS             27251..28162
                     /locus_tag="J8R83_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9573943.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            28241..29233
                     /locus_tag="J8R83_000796"
     CDS             28241..29233
                     /locus_tag="J8R83_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9573944.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            29230..29448
                     /locus_tag="J8R83_000797"
     CDS             29230..29448
                     /locus_tag="J8R83_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573945.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            29461..29871
                     /locus_tag="J8R83_000798"
     CDS             29461..29871
                     /locus_tag="J8R83_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573946.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            29923..32451
                     /locus_tag="J8R83_000799"
     CDS             29923..32451
                     /locus_tag="J8R83_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAZ9573947.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            32467..34677
                     /locus_tag="J8R83_000800"
     CDS             32467..34677
                     /locus_tag="J8R83_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573948.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            34685..35776
                     /locus_tag="J8R83_000801"
     CDS             34685..35776
                     /locus_tag="J8R83_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAZ9573949.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            35797..36339
                     /locus_tag="J8R83_000802"
     CDS             35797..36339
                     /locus_tag="J8R83_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573950.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            36561..36791
                     /locus_tag="J8R83_000803"
     CDS             36561..36791
                     /locus_tag="J8R83_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573951.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            36805..37137
                     /locus_tag="J8R83_000804"
     CDS             36805..37137
                     /locus_tag="J8R83_000804"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573952.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            37182..37730
                     /locus_tag="J8R83_000805"
     CDS             37182..37730
                     /locus_tag="J8R83_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9573953.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            37737..>37970
                     /locus_tag="J8R83_000806"
     CDS             37737..>37970
                     /locus_tag="J8R83_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573954.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVF"
BASE COUNT        12886 a         5977 c         8089 g        11018 t
ORIGIN      
        1 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
       61 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      121 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      181 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      241 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      301 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      361 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      421 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      481 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      541 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttcgggc
      601 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      661 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      721 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      781 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      841 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      901 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
      961 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1021 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1081 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1141 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1201 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1261 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1321 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1381 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1441 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1501 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1561 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1621 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1681 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1741 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1801 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1861 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1921 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     1981 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2041 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2101 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2161 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2221 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2281 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2341 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2401 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2461 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2521 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2581 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2641 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2701 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2761 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2821 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2881 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     2941 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3001 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3061 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3121 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3181 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3241 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3301 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3361 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3421 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3481 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3541 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3601 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3661 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3721 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3781 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3841 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3901 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     3961 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4021 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4081 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4141 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4201 agagtaatgg atgtattgtt acacaatcct ttgtggtttt accttttcat tgtgaatttt
     4261 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4321 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4381 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4441 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4501 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4561 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4621 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4681 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4741 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4801 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4861 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4921 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     4981 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5041 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5101 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5161 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5221 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5281 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5341 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5401 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5461 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5521 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5581 ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata caatcaattt
     5641 tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaactatgt gtatattttg
     5701 accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt
     5761 acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag
     5821 aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg
     5881 cccatgtatg gaaaatcttt ttacaatcta atcattttgg tcgaaatttc tatacggatg
     5941 ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag
     6001 ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat
     6061 tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg
     6121 ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg
     6181 gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga
     6241 cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac
     6301 agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg
     6361 tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg
     6421 tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg
     6481 aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa
     6541 aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg
     6601 atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag
     6661 aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt
     6721 tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg
     6781 aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc
     6841 tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat
     6901 tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag
     6961 caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa
     7021 cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga
     7081 aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg
     7141 aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca
     7201 attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag
     7261 aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag
     7321 aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag
     7381 agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa
     7441 cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac
     7501 gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg
     7561 ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg
     7621 tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata
     7681 tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag
     7741 ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa
     7801 atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata
     7861 tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt
     7921 tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg
     7981 tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg
     8041 gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga
     8101 gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg
     8161 aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg
     8221 cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa
     8281 caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta
     8341 ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt
     8401 ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt
     8461 caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct
     8521 gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt
     8581 tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca
     8641 cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac
     8701 agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag
     8761 aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg
     8821 aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca
     8881 tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag
     8941 atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag
     9001 taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc
     9061 atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc
     9121 gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca
     9181 agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa
     9241 tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat
     9301 caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc
     9361 agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac
     9421 tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag
     9481 cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc
     9541 aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag
     9601 atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt ggttatataa
     9661 caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt
     9721 tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact
     9781 tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat
     9841 aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt
     9901 catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc
     9961 aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa
    10021 accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct
    10081 ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat
    10141 gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt
    10201 cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc cagtagaaca
    10261 gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat
    10321 tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt
    10381 gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa
    10441 ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt
    10501 tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat
    10561 aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca
    10621 tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca cccattttat
    10681 aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat
    10741 tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa
    10801 aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat
    10861 aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat
    10921 tttctctaaa atctttttga tccatttttt catctccatt tattagcttg ataacagtat
    10981 agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg
    11041 cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata
    11101 aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac
    11161 catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc
    11221 gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt
    11281 aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac
    11341 ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc
    11401 tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc
    11461 aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac
    11521 ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat
    11581 gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag
    11641 cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg
    11701 atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac
    11761 ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt
    11821 acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat
    11881 gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta
    11941 acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg
    12001 gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta
    12061 gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta
    12121 ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc
    12181 ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt
    12241 aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta
    12301 acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt
    12361 gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac gatggattat
    12421 ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac
    12481 tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct
    12541 ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat
    12601 gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa
    12661 aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga
    12721 caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt
    12781 tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag
    12841 cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa
    12901 atggatgagc aagatagtgt gaaataactt ataatcaatc gaaaaaccta ttaaataaac
    12961 ctttttgagt agatgcaaca ctgaggatta tctgtataaa agattttaaa ctgtcatttg
    13021 gttatcacgg cgatactaaa attaacaaaa ttggaatatt tttcttgaag atttttagct
    13081 gtcagtatat gatgaaagca tctcatagga ggtgcttttt tcatggttga taattcaagt
    13141 ggaagggttc ttaaatctct aagaaaagag aaaaaactat ctcaaaaaaa gttagctgat
    13201 ttagcaggta tttcacaaag tactttagtt aaatatgaaa aagggtcaag aaaaatccct
    13261 aaagacgtag ataatactct aagcaagatt ctgaatatag aaactctaat aaaagatgag
    13321 gaagataaga ttgagattct catcggtaaa ctaattgcat acagagatat gaataagtta
    13381 cttaacaaag agttagctga taatatagga attagtgaag tattactcag ttatgtgtta
    13441 aatagaaaga gaaatccgtc aaaagaaatg caaaaaaaaa tcgatatttt tctattaagt
    13501 aatgaaaaag aaattttgaa ggagattaat cgtgatagtg agatatttag tttatcaaaa
    13561 gacgataaaa ttgttatggg aaaaagaata cgagaagtcc gaaagaaccg ggaagagacg
    13621 cttgaaaaat ttggtaaaaa ctttaccatc tatacaggca aaaatgttat aagtagatgg
    13681 gaaaaaggta ttaatattcc agatattgaa aaactaatga atattgccta tcttggtaag
    13741 gtcactgttc cttaccttat gtacggagaa gattataaga atatacttcc aaaagatgaa
    13801 agagttagcg attttaaaaa gataaattct tttagtatgg gattaaggat gaggaaaatt
    13861 aggaaagatt attatctaga aagggaggag tttggaaagc ttttttctcc ttcaatttca
    13921 aaatggtcca tagataggta tgagaatggt agagatatac ccaatactaa tcgaattatc
    13981 caatatgctt atataggaaa tctttcttta gaatttttga tttacgggat ataaaaatag
    14041 tttacgtcga tacttattaa gttatcgacg ttttttatta tagaaaaaat ttataaaagg
    14101 aggtttcttg atatgataag aaacaaaaag ggtttgttga aagttgcttt actggcagct
    14161 tttttctaag taactttttg acaagctcaa tggcaacaca agcggaagaa gtaatacaag
    14221 aactaactgt tatgaataac agctagataa aatgggctat gtatgttatc caacaattta
    14281 gtaatcacta gaagcctagc gaaagttcgc ttgataagtt atagatgagt attgatttgt
    14341 agtgtttcca aatcaaaagg gtacagagcc acatgaaata tgttgtcctc tgcagcgtca
    14401 ggatgggaat ccataccatg gagattcgga gatctgtgag ggaatactta cgtggttaat
    14461 atgtcagttg tgttggacgt agtaatggtc atagtgggta gattgactga attcttatat
    14521 gagaaaatga aaccaacaag aagatagggt tatttataca gaattgggga tcttttctgg
    14581 aaaagtaatc ggataatgcg agattcgtac ggtctttttt aaatttctct aaaaaaaacg
    14641 gcatcgaatg ggttgggtga ttgataagca atgaatcata gactgatata gaataaaaaa
    14701 tgattctatt tatcttttta catctatcgt tttttcaagt agccgcaaat tatatcagca
    14761 ttcaacaatt tttgtataca agttctagta aaaggatctg aagaaaaagt tggttgttgt
    14821 gaagataaaa aaagaatcag gttttactga gtttttcttc aaaatttgtg ttattaggtt
    14881 aggacaaaga taagaagaag tatgaagatt taaaaaagga atgaggaaaa gatagtaatt
    14941 tccgattatt ggagtttttt tatttataaa gaagaagcga ataagttgtg attcctagat
    15001 ttcgcgcgtg attaattaat gagcaaaaaa tgcggaaagt tttagtgttt aatacacgag
    15061 gacaaagttt cttaggtatt gaaggcacac gtgtaacggt tgatgggtgg tgtgattgtt
    15121 tcgaggttgg aaaacatgtt gaacttatgg catttactga gctaaaagat aagaacaacg
    15181 tggaattttt cgagagtgat attggttggg acgatcatga agaagtttat ggaaaattta
    15241 ttttgcggaa gggaaattct tatacgaatg gggaagcata agtagcgatt tgttagagat
    15301 cattgatagg attgaaattg tcgggaatat ttatgagaat ctagagttat ttgaggtgat
    15361 agaatgagtg atggttttga acaagtatca ataattaaaa atcaagttcg ggagattctt
    15421 agaaaaaaag gctatttggt agatagttat tttgaaggag attacgaaac atgggtaggt
    15481 gtctatgctc gtccagagaa taaacctacc tatttagatc ctacgacgtc agaagatgcc
    15541 tatttacaaa ataggtatcg agtagatggt tttaagcaag actttgcgga gtggtttgaa
    15601 tgggaaattg aaaacggaga agtaaaagaa gaataagagt acttgttgta tcaaaataag
    15661 ccagtagaac aaccaaacca gtagctagta atgacaataa tactgaggaa tcggatcatt
    15721 atggtatgat tgatatttct cttccagaag atcttaagcc agatcctgta acaattggca
    15781 atagtgtcat gatttttgat tcattagatg aagctatgtc atatggttgg aaagaaatta
    15841 aggatgaagg tagtaattgg tatggcatga gatttggtga tggtgaagtt gccaaaaaag
    15901 ctggtattcc aattgggaaa tggacagttg atttccacga agcaggttct ttttttgttc
    15961 tgtaattata gtgggagggt aaaatcattg atgaaatgtg ttcagataag agcgccagat
    16021 aaaaatagaa gagacagttc acgtcgttat cacttttggt aacggcgttt tgttttatta
    16081 tataaaattc tcaggaaaag gaggaattct tgtgtatgca aaaacgaaaa tgaattggtt
    16141 gaaagcactc gcattggtgg ctttttctca attctgtttc ttggtgggaa ctgctcaagc
    16201 acatgcagaa gaaacgacgg ctatacaacc tacgatggaa gccattgccc aagtcgcttc
    16261 tgaagtgaca gaagtccaac cagcagaagc cggggtccca gctggtgaag ccactgttga
    16321 acaggcccct gtgacagaag cgccaacggt caattccaaa acgactctcg atcagacgat
    16381 tggggaaaca caacacccag ggaatagtcc tggtacttca caaccagttg aagaaactgc
    16441 ctcaattaca acccctgctt cagaaacgtc cactctagaa ggagaaaaag ctgccgaagc
    16501 aacgccttct gtgcagccag agtcttctga gaaacaagcg gaagaaaaga aacgaataga
    16561 agaaacagtg gaacaaccag cggctactgc tgacaaagaa ggaaaaaatg aggaaaacgt
    16621 tgaaaaaaca atctcttcaa ccgcagctag tcaaaatcaa ccaacgaaac caaacaaaga
    16681 atctacggct agtattgaaa atcaaaagaa aaaagagcag aacattccaa aaacaggtac
    16741 acctacactg ttagtaacag taccaaccaa tcgttcggtt cgtgttcgcc gtgcaaccaa
    16801 tgcagctgtt ttaggtggtc ggaaaattga ttggggcgaa aatattggtg ttacttctag
    16861 tccgaacaat ctaaacttca ctttaaatta tatggttcgt tttgagatta atggacaagt
    16921 ggcgttttgt attgagcctg gtgtctcagc cgcagaaggt caagtttata cagctactgc
    16981 tttgaaaaac tatttgaaaa attcaaatgt acggaaaaaa acaagcttga tctcttattt
    17041 aggatatgtc acaaataaag acaaatccga tgaacaatac attgcggcac aatttatgat
    17101 ttgggaagct ttgggcacaa aaatcccaat caaaaatatc cgtgttgatt atgatcgtcg
    17161 aaaagcagaa attcaacgtt tgattaataa ctttggtgaa aaagcaactt ttaataatca
    17221 aacacatacg gtaaaaattg gcgaaacgtt gaaagtaaag aataaaaatg attttttgaa
    17281 atatgtgaaa gacattcaaa aaccaaaagg tgtcaatgta tctattcacg gcaatgaagt
    17341 atggattaca gtcacaaaag aggcaccgga taaagcaaaa attcaattga ataaaattaa
    17401 agttcaaggt gcgccattag cctatcgtcg tccaggagct caaacaattg gtgtgttaca
    17461 tccaacagaa cctaatgcgt ctgttattaa tttacaaatt ctaaaacaag gaaacattcg
    17521 tgtgtttaaa gaagatgcgg aaactggtgt gaaagcacaa ggtgcagctt ctttagaaaa
    17581 tgcggtctat ggtttgtatc aagcagatgg gaaaaagatt aaagaaatta ccttgaaaaa
    17641 aattaacggc aaagtacagg cagaaattaa agatcttgat cctggcaaat atgttttaaa
    17701 agaaatcaaa gcgccaaaag gttatgtgct ttctgatgaa gcaattgaaa ttgttgttga
    17761 acctggaaaa actgtcaatg cgaccgcaaa agatcaagtg atcaaaggaa ccattgattt
    17821 agtgaaagtt gctaataaag atttagtcga ttcaacgaat ccagataaca aaccaaaatt
    17881 agctggcatt gaaatcactt tgacgtcaaa aacaactggc aaagtggtga aaaccgttgt
    17941 gacagacaat gatggttatg ctacttttgg taaaaatacc gttgtctttg atacgtacat
    18001 tctttctgaa accaaaggaa aagaagggta taaactattt gaaccacttg aagtcacaat
    18061 ttctgaaaat gggcaaactt tccattatgt tttagaagat aaagtaattg aacaacgtct
    18121 taaagtggtg aaagtggatc aagaaacagg aaaagtgatt ccacttgcta atacagaatt
    18181 caagattttt gatactttag ccaatcgtta tgtcacaatg gagattccaa atgatacaga
    18241 aacaacggat atctttaaaa ccaatgaaaa aggctttttc ctaactaacg gtacacttac
    18301 ttatggaaaa gatcgctatc gtttggaaga aatcaaagcc cccgtaaatt acgttttgaa
    18361 tcaaaaccca ttagtgttct cgattaccaa tgatacagaa ccgatcaaag tgatccattt
    18421 tgcgaaccgt caagcacgga aaagtgtaaa attattcaag tatgaagaat ggaacaagaa
    18481 gaaaacgccg ctcgcaggtg tgaactttac cttgtataac ggtaaaaatc aagcaattgg
    18541 tgaatatacc actgatcaaa acggggaaat tttagtgaaa ggtctagttg ccgatgacta
    18601 ttacttcttg gaaaatgccc cattagaaag tttccaacca aatacagata aacaagcatt
    18661 cacggttgca ttcaaacaaa atgcgccaga tgatggggaa acgttagtgg tttctgtacg
    18721 taattacttg attccaccaa aactagaaac acaagcgtca aataaagccg atggtgaaaa
    18781 agtggttgat ccattagaaa cgatcgtcat taaagacagt gtttcttata ccaacttgtt
    18841 tgtcggaaaa gaatacacca tttcaggagt attgatgaac aaggcaacga atgcgccaat
    18901 tttacaagat ggcaaagaaa tcacaagtac cttggccttt attgcagaca aagtcaatgg
    18961 cacaaaagac cttgaatttg tggttaatgc tagtgttctg aaaggtcaaa cgatcgttgt
    19021 ttttgaaaaa cttttccgtg atggcattga agttgcagca catgcggata tcaacgatga
    19081 agcccaaagt gtgaaagtga ataatccaac cgttcatacc acggctgtct ttgaagacgg
    19141 attgacagtc gcagacccaa caggattgtt taccttaaac gataccgttg aaattaccga
    19201 gattcttcca ggaaaagcat acttggtcaa agggatctta atggataaag caaccggtga
    19261 acccttgctt gtgcatggaa atacggtaga aacgagtgtt ggctttattg ccaaagcaga
    19321 aaatgaaacg gtgatcgtac catttacctt tgatttgaca ggtataaatg gtcgtgaaat
    19381 cgtcgtgttt gaaagtcttt ttagaaatga tgaagaacta gcaaaccata aagacatcaa
    19441 cgacaaaggg caaacggtac gagtaactaa cccaagtgta cgtacaacgg ctacacataa
    19501 acccactggc ttgaaagagg ttaatccatt aacgaaagtc accattacag acgctgtgaa
    19561 ataccacgat ttggtcgttg gaaaaacata cacagtcaac ggtgttctaa tggacaaagt
    19621 aacggaaaaa ccagtgctag tagatggaaa agaagtcaca agtaccttaa cgtttgtggc
    19681 agaaacaacg gatggtacag tcaatctaga ctttattcta gacgcacgtg cgttgcgagg
    19741 caaagaagtc gtggtctttg aagatctgtt tagagaaggc gtattattgg cttctcacgc
    19801 agatattacc gacaatgacc aaaccatcaa aatcagtaat ccaaccatta cgacgaaagc
    19861 gacgaataaa aatggcggaa aagagatctt ggccttgcca aatcaaactg tgcttgaatg
    19921 ggtcaaagta gacggtcttg cgattggtca aatctatcgc ttaattgttc aaggctactt
    19981 aacaccagac ggcacaccat ttgaaggcac tcatgcggaa aaagtctttg cggccgataa
    20041 agaaatgatg gaattcttat ttgaattctt agtggacggt cgcaatcttg caggaaaagg
    20101 cttgagtttt gcggaatggc tccaagcgaa aacggaagat gagaaagaaa cgtttgaaga
    20161 agtggcgaaa cacaatgtag atctaacaaa caaagatcaa acggttcaaa ttgtggaagc
    20221 gccaaaacca ccgcaaccag tgaaaccaga acaacgggtt aaaccagcta ctgttgtacc
    20281 aatgttgcca aaaacaggtg aacaaacaag tagtatactt atggttcttg gattagtagt
    20341 attagtcatt gctttaggta taacacttta taaagtacgt aaagccaaag attagtcatg
    20401 aggaacaagc ggttaggatt tttaaccgct tgtttgattg taatgtagaa atatttagaa
    20461 tttattttgg tttttaagag gaggaaaaac tttatggcag aaaaagcatt gcgtatgaag
    20521 aaagagtttt taggtcaagt atttttattg ggttcacggg aacctaatcc accaaaggaa
    20581 attaatggtg tgtctgggcg atatgttcaa ttacaagcag agtgttcgcg agaagaacag
    20641 cctgcttttt ttgtttatct cacagctgaa gaggataaaa gattacgatt accagaaaaa
    20701 gaggtgcgta tttcatttga agaagcttat tttgtttttc gtaaagaacg agtgaatagt
    20761 cgtgaaacaa atgatatggg acaaacagag cgtcgaacaa ctggctatca agatgttggt
    20821 gtctttttaa ctggtgtaaa aattggggag gttttgtaag atgggattaa aatttccaaa
    20881 taattatgac attacagaag cattagatga aacttgttta ggagccgtac gctttggcgc
    20941 attagaagag tctgatcgtg tatttgataa tgaaacaggc gattatacgg gagaaattcg
    21001 atcacagcga gcacaattag tttttggaaa tccagatgaa ccaaagattg cacgacgagt
    21061 taaatttcca gcagatgtag atttgactgg ttttaaacga cgtgatcctg tgaaattaat
    21121 tgatccagaa tatcatgtgg tatatattcc agcacaagat ggcaatcgtg aatattcaga
    21181 tttagtgatt tatgcgaaag gattagagaa agtagaagct ccaacaaata atcctaatat
    21241 gaaacaatca caagaaaaag gtttagatca aaaacaacca agtgttgatt ctaaggaaaa
    21301 agagaaaaaa taaggttttt ttgaaagaat aggaaggagt cttcctattc tttttatcta
    21361 agatagaagg aaggggagat tttgaattca gataaaacca atcaaatact ttgagagatt
    21421 gtgcttgtta tcaaaatatc caacaattga ttgagtattt tggagacaat ccaacgattt
    21481 ttgtacaaac aaatgcatat atttgtgcgg ttattgggca gtgtatgttt ttacgtgatc
    21541 ttgttcgttt ttcattaccg taccagtgga aacaagatca tcaggaagtg atttggattc
    21601 gtatagtacg aatatgtaat atgtgtgcac acccttataa aaatcgatta aatctttttc
    21661 gattatgttt ttttactaaa tgtgatattc ctgtattagt tgctttttgt caaaagtttt
    21721 tagcacagga aaagtaaaaa cagaaaggag gaatgtgaca attgaaagct cattttttca
    21781 agtatcgtgg tcggcgaatt cgctatttca atcgttattt atggttttgc tattatggtt
    21841 tctttttgtt tccatttttg attctgttag gttggtttag ttggaaagta ttttatccac
    21901 gtttaagtac gttttcgaat tggcaaatgt atcttattcc tggaataagt attgtgttgt
    21961 atttgttgct ggttagtggg ttaattttag ggttgatgca ttggtcgcga ctaaaagaag
    22021 gatattttgc ctctgtttat tggcgtcagt tacttgttcg aatgttaatt gacaatcggt
    22081 ttgtttatac aaagaaacaa gttagtgaga aacaaacaag ggaaaaaatg agattaccaa
    22141 aagtttattt ttatcaaaag aaacaagaat tagtggtttc ttttccttta gatggtgggc
    22201 gttttcacga acgattttta aaaatgggtc atttgttatc tgaagtattt ttgcgtgatt
    22261 taattcgtga agaacgagaa aaagcccgaa tcaattatgt attcctttca gattctggtc
    22321 ggattcctat tgatcaatgt atagcagaaa atggacgtat tcatttaatg aaaactttgg
    22381 attgggtata tgatcaatca ccaaatatgt tgattgctgg tgcaatcggt ggtgggaaaa
    22441 cctatttatt gtattcttta attcaagctt gtttaagtgt tgggacagta gatatttgcg
    22501 atggaaaagc ggcagattta gcagcattag gtgacgtcga tgtattcaaa ggacatgtgt
    22561 tttacaaaat aaatgaagaa atgattattt gtttacgaaa tgcattaaaa gaaatgaatc
    22621 aacggtatgc ctatatgaaa accatgaaag atcctaaata tgaaccaggg aaaaattatg
    22681 cttattatgg gttaccaccg cattttatct tttttgatga atgggcagct ttttatggtt
    22741 cgttggatat ggaagcgaga aatagagtcg ataaattgat tcagccatta gtattaaagg
    22801 gtcgtcaagc agggatgtac attattttag caatgcaacg accagatgca gaatattttc
    22861 caagtggtgt tcgggataat ttaacattcc gtatttctgt tggtcgattg tctcccattg
    22921 gttatttaat gacttttgga gaagatttta aaaataagcc attttacaac aaagatcaac
    22981 ctggtcgtgg atatgctttt ccaggatttg atgtacctgt agagtttttt gcgccatttg
    23041 tttacaaaga ttatcacttt atcaaagaat ttgagaaatt tactgaaatg attgtctatg
    23101 attttacagt aaaagaggat agtcaagatc aaacgatggg agatgataat cagttgttac
    23161 aagaacaact agagcgccaa atgtatttag caaaagatcc aaaaggaaca agtttttctg
    23221 atgcgcatat tttgtaatca actaaggagg tgaagttaaa tggcagagag ttgttattat
    23281 agagtagcta cagcaatacg aatgattaat ccttctcttt cttccagaac gttttatgat
    23341 tggttgaatc gtattgaaca agtaactgat taccgctttt tgcgcaaaga acgtgttttt
    23401 acaggaaaag ttattaatca agtattgcta acgaaaaaag atatagaacg attgactcga
    23461 ttgtatcatt atcgagtaga tttagaagag gatttaactt tgtcaattta tcgcgttttt
    23521 tctcctgaaa aatatagtga aataacaaaa ttagatcatt taattttgta gttattatct
    23581 atcgggaggg ctctagacgt agtctggtag ccgcactctg cctggcggtg cgcattaagg
    23641 ctgcgaagca tgggcctata atgcgcactc gctagcagcg tgtgcagctc acaaagaggt
    23701 cgtgcgcttg cgcacggcct ctttgtgtaa agccccccga tatataatat ggggggcaga
    23761 aataacataa cacatagaaa aaagttttat aaaccctttt gtatcaagtg attatctaag
    23821 gtcagcagtt gtactacttt tcccaaaaaa cgagggggac tagttgatat atcggtgttt
    23881 ctaaagggtt aaaaaaaatc gattttgtta ttttataaaa ggagcgagaa aatgacaccg
    23941 attgagctaa aaagctacag aaagaagtta agtgcaattc ataatataag tggagataaa
    24001 aagccgctat cacaagcaag atttgcgcaa ttgatgggct gctcaaaaga ttacattaga
    24061 aagatggaac aagggaaaag aaaaatccca gaggattttg aacaacgaat caaggaacgc
    24121 tttcgattgt atatgaaaag cggaatagat cttcgagcaa tgattgatta tttgcgtctt
    24181 tccttttttg ggacagacta caaaacagtg attcaacgtg tattacgaat ggatctgaca
    24241 gaatttgaaa cacgtccaac gggcttgtat ctttttgact gtctttctgt tcgtgggaat
    24301 atctgggtgt tctggcattc aaaacgaact gtaacagaaa atgtacttgt gcaattttca
    24361 ggacaaggtt gccgggaata tgaggaagtc atgcgtgaac aacaaacaga ttggcgaaca
    24421 tggctatatt ccatttggaa aaatcaagga aagttggaag ctggttatac acgtgtgcaa
    24481 tgtagccgat tcgatattgc gttagatgaa ctttggggat tggaaacgga agaacatttc
    24541 gatctctttg aattactaga aaaacaaaaa gcaggtttat tagaaatgga ctttaagaga
    24601 ttccagaata ttggcggttg ttttttagat gatggctatt ttcgaagtga aggattatct
    24661 ttgtattttg gatcgcgaaa gagtcctctc ttttttaatt tttatgagaa acgttttgaa
    24721 attgcgaacc gagaaaaaat ttcagaatta gaagcattaa cgaaatatgg tatttataat
    24781 cgatatgagt tacggttagc caatgagaaa gcaacacaag cagtagaagc atttatttta
    24841 ggtgattcac cgaaacgttt aggagagatt ggcgttggtt taattaatgc aaaacttatt
    24901 gtttgggata gactggaaag tgatgcacgg attgttgata aacgatgggc aaaattattt
    24961 cgttcgatgg aagaattgga ttttacagta aagccagaaa aattctcatt agatcgttca
    25021 gaacgctggt ttttgaaaca agtagctccg acattaaagt tgttacaaga agcagatcgt
    25081 attttaggaa gagactttgt acaagaaggg attgataatg ccgaactaaa tgacgagcaa
    25141 caaaactatc tagaatggat gggaacgtca ggagggaaaa ttgcatgaat gcatatacga
    25201 caacagaatg gctgcgcctg ttggatttaa aggctgcaat cgaagcatta aatgaaaaga
    25261 tggttgattt gtcttatttt cgttttcgag ttccttatat tgaacaagcg gtaaaagctg
    25321 gacgttatca ggaaaaagag aactggcaag aaattgcacg cttattagaa gttcgtaagg
    25381 gatacgaaca agaactcgaa gagttggaat ttagccgaag gaaaggaagg ctagaattca
    25441 ttcgctttta tcgattttca ttgccaatac ctgcgatttt agcggttaaa aaaggctgcg
    25501 ataaaatgaa gatatatgaa aactgtgtgg cagcacttag cagcgaaaaa cctcttatgg
    25561 aagaaatttc attggtgact gtcacttggg aaatgagtcg ccagccaaca gaagaacaga
    25621 catatctttc tttagaagag attgagatag aattagagga aattggtcgc tatgccactt
    25681 gttctaccta ttgtggatcg gtcattagta ttgctggtgt gattgtctaa atgaaaaaaa
    25741 ttatgattta tgttggtgcg tattggtcac gtgatccaac agtattagaa aatccagagg
    25801 cggtacacta ttgcttgcgc caattattct atctgtataa agaacgatta gaatcgttga
    25861 ttcgtcagtt accatatact gacagacgtt tagatgaact tcttctaagg tatccagcaa
    25921 tgtataaacg acgaaaaaat agattgttac cagaagagta tcccattgaa aaacatgaac
    25981 ttgaagggcg atttgtggct tatttctatg atgatgttcg tatgcgctta gtagaacaac
    26041 gaatggaaat agaaaatgat cgctactatt ttatcaatta ttgtaagaag cgtaagtatc
    26101 aagtaactga tgatttttat gattgtattt tacaagatgg ggaagtgatt ctatccaaaa
    26161 ttgctccaag ttttcgtgaa cttgtgccga ttgatttttt gaaaaaatgt catttgcgga
    26221 ttcttccgta aaaaagagct ataaaaggaa agaaaagtag aagccaaatc ggtttctgct
    26281 tttttatttt ttttaggaag gagaagatgg tatgtcactg gaatttttag gagagccaat
    26341 tgaaaaggaa gagttcgttt cgcattatat ggatttgttt attcaggtga taaaaaactt
    26401 tgtgcgattg atgaatttta tccacgcgaa caagactatc tagccgctga acgaataaaa
    26461 atcagtttat tatgggaaaa attcacagat gaaaataacc gaccgccaga ttatcgctat
    26521 ttatcagatt gtttaacgaa taatgtgctt tctaaagaat acctatttca caaacgtgag
    26581 aaaaatcaaa tgtcggttga acatttttgt gattgttata ttgcattatt gcgtagtcaa
    26641 cagttattaa cagtagaacg atatggtgca gagtttggtt atgtcttgca agctgagcgt
    26701 catagagcta caagatgcta tgaaaaagaa gatcaagtga ttgatggcta tgaagaatta
    26761 tgtattcgaa acaatcgcta tttgcaacaa cgtttatatg aacaattgat gatggatttt
    26821 tcaaatctct atagagggta tgaatgttcg atgattcaag aaaggtagaa gaaaaggggg
    26881 aatttttatg tggcgattat tatttttggt ggtatgtggt atggcattgt tctatgtgta
    26941 tcgtgtctat ctctatccac gaatggaacg atggacaagt tggtatagag atcctttaaa
    27001 acaacgaaaa ggattgaagc ggtatcgtta tgaattactt gttgaatttt cggatgggcg
    27061 acaagcacag tattattttt ttgcaaacta tccaaaatac aacaccagtg aactattgat
    27121 tcaattattc aaaaataatc catatgttgg gttagaagaa aacggacggg agttctttta
    27181 tcgttcagat aatattagtg cggcgtctat gaacaaaaca cgaattgcat aaaaaattgg
    27241 aggaataatc atgaaaaaaa caacattagc agtcgtaaca acactaggaa tttcattatt
    27301 ttcgtttcaa ttagggagtt cattggttta tgcagatgaa actgtagaaa cacctaagtc
    27361 agaaattgta gaaacattgc caggggaagg attaccagat gttgagacag agctaaatgg
    27421 aggaacaacg gaaaaaccag cagaacctga acaattgcag tcagagaaac ctgaaaaaga
    27481 gccagtgaca ccagaaccag agtttcctga atcaacttta ccgactgatt cgatcgaaga
    27541 agaaggtgtg catagttcaa caacaacgga ttcaagtata gtcacaactc cggaacaatc
    27601 aggaacaacc agttcttctg aaaagaatac tgattcgtca agtacggaac agccaacgat
    27661 gtcgtctacc agtgaagaac aaaaagaaga accgaaacaa cctgttgaaa aatcagaagc
    27721 aattccaaaa gaaaataaac ctattgttcc agcaaaagaa gtcacagtat cggtaacccc
    27781 aagcggtgaa attacgacga atacttctca aggaatgagt gtaccgattg tcactagtaa
    27841 tgtagaggaa ttgacccata ttccaacacc aaccacccca ttaaaagtag caggtgatca
    27901 aacaattgtt ggtgtaaaag atggtattcc attaatccaa gatagtgaag ggaatttggt
    27961 aaaggatttg tcgattcctg taaagaaact tccaagtggc aatattgaaa tcaaaacagc
    28021 agatggaaaa acaaaagtct taccaaagac tggtgaagaa atacatgttg cactttctgt
    28081 tctaggagga gtgttgacaa gtattgctgg atttgttgga tataaaagaa agagaaaagg
    28141 aatagaaaat gagggtaatt gaatggacta tttttcagaa aaacaagctt atcgttgtca
    28201 atcgtacgta ctagtaaaaa catactagaa ggagtagctt atgaaaaaac gacaactacg
    28261 gcggaaagaa aaagtttata cagagaaagt accgaagcaa aagaaaatcc attcaaaaaa
    28321 agcagtgaaa tggatttggt gtttggtttt atttctttgt ttttcagggg gcttggcatt
    28381 ttttcaatcc atgaaaacga aggttcaagt gtcgtttttg aaagatgaaa tccaacaatt
    28441 acaaaagaaa gaagtacaaa gtcggtcaga attaacgtac acacctgaaa ttgaatcctt
    28501 tatgaatcgt tttgttgctt tgtatatgaa tacattcgat aatcatgaac aagaacaaca
    28561 acgtcaagaa acattaaaaa aagagtttta tgcacaaaac tttattcaag aaccaggaag
    28621 tgtttcaggt gttcgaaaat taactgctgc ttcgtttatt ggattaaaag aaattgaaac
    28681 cattccaact gctagttata aagtaactta tgatattcgc tcgatgaatc cagagagtaa
    28741 gaaagaaaca agtgtgacaa tcacacaagt actcaatctt cccttttcta tttcaaacaa
    28801 gggctgtcgt attattgctt atccttattt tacggcacta ccaaagaata cagaaaaaca
    28861 acgaatgatt acttatgatg acacattata cgaaacggtt gatgcgtcgg aagcgaaaga
    28921 tgttgaagga tttgtggaag atttcttaga taagtatgcg aaaaacaatg caaaagatat
    28981 gtcatacatg atgaaagaac ctgaaggact caatcaaaca gctaaagttg atcaagtaga
    29041 gatgaaagta ttgcgttata aagaaacgaa aaaacctttt attgtaaaag caacggtcgt
    29101 ctttcgagat ggtgatacgt cacttttaca aaaagaacaa atgacgattg tcattacgaa
    29161 aaaaacaaat cagtattatg ttgaaaaatt aacacataat tggttggata ggaaaggaga
    29221 agaacggaaa tgacactgaa gggaattgta gattttatat taacgcaagg tggctatttt
    29281 ttaataatgg tggttgttta tctgggattg cgaaatttta tgaaatcaaa agtaggaaat
    29341 gcattaatat ctatcgcagc aggtgccgca gtttatttct tcttaaatga tccaacacgt
    29401 gtatttgatg cgtttggtaa aatcattgaa aaattattta tggattagga ggatagtgaa
    29461 gtggattggg aaccttatga ttattcgatt gtttatgcgg aaccttatcg cgtacaacag
    29521 attacaagca attggcgtct tccatttcca gttgcattag tcaatgcagc aacttttttg
    29581 ttggtcgtaa tctttgaata tttattttta cgttcattta ttggttgggt catttctttt
    29641 tttccaccag caggagttgt tttttatata ggactcccct atttatgtgt gttagcactg
    29701 gcaaaactaa aacctgatgg aaaaaaagtg catttttatt tatgggattg gttttgttat
    29761 atgattcgta tgatgaatgg tgattgtgtg tattataact gggacaaggt atcaaacaat
    29821 gcattggaag aattactttt tgtgaataag tatgtttatt tagaggatta gaaaaaggga
    29881 caatcaactg gttgttcctt ttttattggg aggtgaaatt cattggtgct tgtaaaagaa
    29941 ccagtaaaag cattcaagaa aaattgtttg ttaaatggag aggattgtat ctgggcctac
    30001 tatcatgttt ttccacgaac aatttcaaaa aacacaccaa aaaagacaca ggaaataaaa
    30061 gaaatgatgg ctcgtttact gttgctttta gcagattatg aagatgtgga gttggtgatg
    30121 tatccacgaa caatgaattt acggacgaag tttgacacat taggaaaggg attttctccc
    30181 gatagtcaag caattggtgc gtattatgca aaagaaacag tgacattgtt ggaacgagaa
    30241 ggtcaagtct atcgtccttc atttatttta ggaatcaaag tcaaagaaaa agcaacggtg
    30301 gagagttttc atgatgtaat aaatctaatc tggttagatt tagcaggaag tttagcacgc
    30361 ttatttggat tagaagtaga tgatttggaa actttgtttt ctgaaagtga tccttatgta
    30421 aaagaagtga cacaattact ttatagcttt tctattcgtc ccttagtaaa aaaagagctg
    30481 ttgtatctca atcgtctgca atatattcga ggaatggctc acaaagtaga agaacaaaat
    30541 aattgggaag tactgaaaga caatcaagga acgtatgtac gtataccgaa ggaacataaa
    30601 ggccttcttc aattagaaga tgagttaggg agtagttatt tagcattgtt gcctattggg
    30661 gaaacacctg aaaatatgag aaattgtgat ctatttcaat ttgctcagga tctttctttc
    30721 ccagcagaat tgcgaatgaa aattcactat ccacgcttga aaggacaggg aggtattggt
    30781 ttaaaactga attggctatc ggaacggttc aaaacagagc ataaggaatt ggttcaaaat
    30841 gatgaagaac ctagtgaacg cttattaact gttcgaggat tagtaaaaca tttaaagcaa
    30901 cgagtagata atgggcaacc tgtcgtcgat tggatcgcat gttttattgt atacggtcaa
    30961 acggttgaag aagttcgtca aaatagtgca acggttattc aacaacttca tacgattatc
    31021 catatccacc gtgcaaaaaa tgatcaacga gaattgttct ataaatgttt attagggcaa
    31081 ccattgggac ggcagttaca ttggaagcac cgaacaactg tagaagcagt tggcgaatgg
    31141 ttgttttcag cagtatcaga attaggtatg gaatccggct ggtatattgg tcggcaagat
    31201 acattagggg atggtggttc tcgaggagaa aaaacaccat tagaagaatt aatttatgcg
    31261 tcaaatcgtt ttgtcttttt gaatcttcta gccattgcgg aaggaatcaa aggtgcgttg
    31321 tttgatgcgc ctcatgtagc agtaactgga aaaaccggta aagggaagac ctttttagtt
    31381 ggcttgctct ttttgtatag ttcgtttatg aatgtacaaa gtttatttgt ggatcccaaa
    31441 ggagaaaagc gcaaatggtt tacgaaactc attcaagacc cgtattatca gaaacattac
    31501 cctttgtttg tagaacattt gcaaaaaatg agttatgtca cgttagatgc tacaaatccc
    31561 cgtaattatg gtgtattaga tccaattgtt tgtttatccc gagtagatgc gaaacaagta
    31621 gcccaggata tgattgatga gttaagtccg ttaggtacca atcacctttt aaaaggggcg
    31681 gtattaaagg gaatccaaga agttttagtt caaaaagaag ccggacaaca agttggcttg
    31741 atgcatgtgg tcgactattt agaacaaatg gaacaaaaag aggttcgaga atatggtgag
    31801 tttttacgct tgacggtaga agattcgatt ttacgtttag gattttctta tggagaaaac
    31861 ccgggattag actttaatgc caaaacaacg attttagaga tccaagattt gaaattacca
    31921 aatgacaatg tccgaccaga actatataca gatgcggatc gaaagtcttt gtgtttgatg
    31981 attagtttag gtcgtttttg tgaaatgttt ggaaaacgag atagtagtaa gaaaacagcg
    32041 atttatttta cagaagcatg ggtatttaat aattcgaacg caggacgtag tattattgca
    32101 gcaatggcac gtgtggggcg ttcccagatg aatcaattag tgttagatac acaatttatt
    32161 ggtgacttag gttcagataa agaaaaaggg aattttggtg tcgtctttgc ttttgatgaa
    32221 gacagtgagc gagaaaagat tttgaatcat ttacgtttgg aagtaaatga agcgaactta
    32281 gctgaaatga gccacatgat taaaggacag tgttggatgt tagatcccta tggacgtgta
    32341 ggaaaactca atgtacacag tttgtttgaa gaaatgaccg ctgcattaca aacaacggaa
    32401 aaaacaagtc actctcaagt agaagaacag gatacgttaa tcatgcaata gaaatgaggt
    32461 gaaacaatgg cttatataaa gcataaggaa aagaaatggt gcgttttgtt ttttttaacg
    32521 attggattcg gactgctttt tgttggtgga ttggtgtatg cggcagaaaa gcaggtggat
    32581 caatcgatct atgagattgg gaaatttcat attgatacct tttcttctta tttatctgat
    32641 agtgaatttt cattaggcaa aatgttattt ggggcaaatg gcacagattt tctaaaaatg
    32701 atgacgaata tgttctttag tttaagtaaa ttgatttggc aaggccttga ttttgtcatt
    32761 gagaagctct atgaaggagc tgcaatgaac gagttaattc accagttttt cactttttcg
    32821 gatactattt attcaaaaat atacgatcct attggtgcgg ggattgtcgt cttgtatgtg
    32881 ttatatctat ttactcttcg tatatttaga gggaaacatt acgcaaaaat ggtgtttatt
    32941 cgatttctct tcgttgtcat tttttcaatg gtttggtttg gctatggtag taacgtacct
    33001 agtaaaggag aagcttttac caaagggtta aatgatttgt ccgtggaggt agaaggcttt
    33061 attttttctg ctacaaatag tctagatgaa ttggcgacaa aagatgtcaa tggtgtttta
    33121 gtgccaacga cacaaaagga agccattcaa aaagtgcgcc aactttatta taaagcggct
    33181 gttgttgatc cgtatatatt gttaaattat gggacaacaa atttagaaga attgtatcaa
    33241 gcagagattg aaccacaaga atttctagcc aaggaagcgt caagtgaaga attatctgat
    33301 attgagacaa aagtgaccac tgctgcagga gaagatagag ggaaaaagaa ggcttatcgt
    33361 gtctatattc aaccaactaa agctgtttat aaagcagtcg ttggttctat ggtgccattg
    33421 cttaatctaa gtattggatt accacttgta gtgattggca tgattcgttt tatctttcaa
    33481 atgttggtgt tgtgtttatt acttgtgatt cctttttcat tactcgcttc ttttgttcca
    33541 gtatttgatt atatgctcat gaatacctta aagtcctttt tgggcttgat gtttcaaaaa
    33601 tctttttaca gtgtgattat tttggtggca tttttgatct ataacatagt agacgattta
    33661 attccaatga atactgtttt tggtttttta ggaaatatgt ttgtcaaagc actcctatca
    33721 attttactca ttgtaaaacg gaaagattta ttaaagaaac tagggttagg agctgcagat
    33781 caaactataa acaacacgaa aaacatagca agtcattctt tgtctcaaat gaaacaactg
    33841 cctggtcaac tatcaactgc tggacaaaat ttggcaatca aaggtgcagg attagcaggg
    33901 aatgtgtatc gagcaacgaa tccactcgct tctgcagcga tacatggatt tcaaaagttt
    33961 caacaaaaac gtacaccaca agaatcggta aaagggaggc aagtggttaa tccctttgaa
    34021 ctaggtgggc gttcaaatca agccttgcct tatagtggtc gtcatgttcg ttatcatggg
    34081 gtagagcctg aaatgtcttc taccaaatcg aaaacagagt ggaattctgg tctttcaaat
    34141 ggtttgattc caaattcgtc catgaattca gtaagaccaa aacaacaggt acaatcattg
    34201 gcacaattga gtaagcaaca agggaataat caaagaaaac cattgttaaa taaaggtatc
    34261 gcttttgttg gtcaatcgat tccgttgcct tctggaaaag tacccgtgcc acaattaaca
    34321 gctgctggtt ctctttcaca acagattcgc caagtgaaaa atcaggcgaa aaatgggagt
    34381 tatccagcaa tgcagcagtt attgaaccaa tactctgttc ctaattcgtc ggtagccact
    34441 ctatcaggaa atcgttctgt gcaacaaccg gggcaacgtt cgtctgaaag taaaccgtcg
    34501 atttccgcac caaaatcgtt acaacctgca ttttcttctt tagataagcc aacagagcaa
    34561 tcggaaaaaa tagaaaagga tcctaaaaca ctgccgattt tggacgcaaa accaggaact
    34621 gattttactt taccaaaagg acgaacagtc caaaaaccat tatcgaagaa aggatgagga
    34681 agaaatgaag aaagggtgtc taggttgtct tcttttcttt attcttccct tttttctatt
    34741 gccattcttt ttttcaggag aactttctga gcatggagga gaagctacag gtctagctgt
    34801 cgcttttaat ggggaatata ccgaaggatt accgattttt tcagagatta aaggacgtgg
    34861 tccaatcaca gatgaacatg cgcaagcagc agttggtgca gctgtaaagt atcagttatt
    34921 accgagtgtg attctttctc aattaggcta tgaatcagct tatggacagt cacaatctgg
    34981 aagaaacgat acgaactttt ttgggattac ctggtttcct ggttgtccct acccacaagg
    35041 ttctgcacgt ggaattggtg gttctgaagg tggtttctat atgaagtttc cgaacttaaa
    35101 agcttgttat gactattatg gctttatggt ggcgagccaa agcaacttta atcaatgtgt
    35161 gggcaataaa gatcctggaa gttgtttatt gattctaggt cgtggaggct atgcggcagc
    35221 aggtattacc gaagggagtc cgtattatcg aggagcaatg agtatcataa cgtcctataa
    35281 cttaacggaa tatgatactt ttgcgatcaa gcattggaat agcctaccaa caaaaaaaac
    35341 ttcgcttatt gcaggaaaaa gtaaaggcaa tgcgaaggtt ttggatcgga tcattggacg
    35401 atccgtaaat aatggggaat gttatggtgg tacggcatgg tatgtatctc aattaggtgg
    35461 cccacagtta atgggttctg gacacatgtt tgcgatgtta ataggggaag attataactg
    35521 gacaacctat ggttggcaag taatcatgaa cccaaaacca agtgatttac aagcaggaga
    35581 tgtggtgaat tggcaagcag gtggtgcatt gtctcctgga atctatggtc acaccggaat
    35641 tataacagat gtttcatatg gcggacaaca tttctctagt gtggaacaga atgccgagca
    35701 aggacggatt atggctcggt atcaacgcac gtacaatcaa acaaaaattc gtagtctggt
    35761 tcgtaaggtg aaataagaaa ggcagtgact agaaacgtga aaaaagggat aattttagta
    35821 tttagttggt tatgtttgat aggtcttact ggttgtcatt ggttttcttc tgaaaaacaa
    35881 aaaacacaat tgagaacgac agaagaaaca atcgaagcag taaaagaaac aagtggaact
    35941 cttcaaagta ctgaaagtaa cagtcaaatt ggttcattag aagacgagac agcgcaacaa
    36001 atgcaaatag atgaaatgac aaaaaatttc ttaaaagatt ttgctagaaa atggagtaat
    36061 ttcacagatg tttataaacg caatcaagct gtgagggact atatgacaga tcgttgtatt
    36121 aaagacaata gtattgatgt agacccgcat gtacaaatga aaacaactgg gaaactttac
    36181 caggtgacac aagatataga gaatccggat caatatttgt tatttggaga agaaacaatg
    36241 aataaggtta ctcaatttgt attacttcaa ttgaaagtag atcaagaagc tcaaaagatt
    36301 gatgcgatca agatttatta tgtacggagt gcgtattaaa ataaaaaatg aacactcata
    36361 tttattatac accgaagaaa tagaaaaaaa cagactgttt ttttaagaaa aactatgtca
    36421 ttctttactt gaaaaaagtt gttataggac agaaaggata aaacaaaaac ggaaaaaata
    36481 tgtcttatga ataactataa gaactattct attttttagg agatggatac gagatgaaaa
    36541 aactaattgg ctatagtgtg atgtgtattg gatttgttgg tgtgggattg tttgtatcga
    36601 ctgaatctgc ttctgcggct gaatggtata atcctatctg gtataatccg aacattgaat
    36661 gtcaaaaagg ctatccgtat ggaccgacaa atctgaaaaa tggaaaatgt agagtaaatt
    36721 ggaatggcgt tgtagatagt gtaattactg gttcaatgga ctctgctcta catggcttta
    36781 cgggtcacta gaaggaggaa gaaaatgtct gaagagaaaa aagaaatcgt tgaatcatta
    36841 gtagctttaa aagattctct ttctaagatt gaatatgttg ataggcaaga aattcaaaaa
    36901 ctaattgatg atactattat tgaaatccaa gatgcgcgtt gtgaaggtat aaaaatttct
    36961 gtagctttat ctaaagtaat agaaaaaatg aaccgttcat tagcgtttaa tggattgaag
    37021 ctagatagac aaactagtct gatatgggat catttaaaag acttgtatga caagtctaaa
    37081 agaagtgaac ggactgctgt atcaatctta aaaggccttt ggggaatgaa ttcataaaca
    37141 agatatttaa aaagtaactt attttttatg gaggagaaat tatgaaaaga ataattaaaa
    37201 tatttggtgt tttaggtgtt ttcttattag gtttaagtac ttttgttagt actggaacaa
    37261 gtgtgtatgc cacagaaaaa gtgaatacag ttgatttaga aataaagaat aaattagtag
    37321 atgaattaac tttttatttt gatacagttg gttttttaga cgaacatggt gtataccata
    37381 taaaggattt tggtgctatt cgtgaacgaa tcagtcaaga taacgaacaa ggaagagcag
    37441 caagagtctt ttatgaacat attattgttc ctagaatgga gaaagttgat tggaaacgat
    37501 atgctggatg tgtagccatt aattctcttc ctggaggagg agtggcttgg gctataggta
    37561 cgcagggaga ttttattgaa gcattaaaag cttttaattt tgaaaaagct gcggatttat
    37621 tattaaaaat tgcagaaaaa caattaggaa aagctgcagc taaagagtta gctaaggtaa
    37681 atattgtagc aggaattgca gcagctgctg ctagctgtgc attagagtaa aagtttatga
    37741 aaagtttaga acaagagcat atggctttta aacaagcaat gtttaaagaa aatatctatt
    37801 taaaccataa ctatattcgt gtttctaagg catgttcacc agtattgaat atgcttggag
    37861 gtggaaatgg attatatcat ttactgtttg tcgatgtttg ttggttaatt tttttaccag
    37921 atgaactagt tatagtcaat gaaaaaataa caagtaaaaa tgaagtgttt
//
LOCUS       DADQCX010000017        37160 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.017, whole genome shotgun sequence.
ACCESSION   DADQCX010000017 DADQCX010000000
VERSION     DADQCX010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.017"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            129..992
                     /locus_tag="J8R83_000807"
     CDS             129..992
                     /locus_tag="J8R83_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9573955.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1121..2743)
                     /locus_tag="J8R83_000808"
     CDS             complement(1121..2743)
                     /locus_tag="J8R83_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9573956.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2992..3513
                     /locus_tag="J8R83_000809"
     CDS             2992..3513
                     /locus_tag="J8R83_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573957.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3699..5429)
                     /gene="spxB"
                     /locus_tag="J8R83_000810"
     CDS             complement(3699..5429)
                     /gene="spxB"
                     /locus_tag="J8R83_000810"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAZ9573958.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5594..6412
                     /locus_tag="J8R83_000811"
     CDS             5594..6412
                     /locus_tag="J8R83_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAZ9573959.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6515..6712)
                     /locus_tag="J8R83_000812"
     CDS             complement(6515..6712)
                     /locus_tag="J8R83_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573960.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6881..7459
                     /locus_tag="J8R83_000813"
     CDS             6881..7459
                     /locus_tag="J8R83_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAZ9573961.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8504..9007)
                     /locus_tag="J8R83_000814"
     CDS             complement(8504..9007)
                     /locus_tag="J8R83_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAZ9573962.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9366..10391
                     /locus_tag="J8R83_000815"
     CDS             9366..10391
                     /locus_tag="J8R83_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9573963.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10714..11592
                     /locus_tag="J8R83_000816"
     CDS             10714..11592
                     /locus_tag="J8R83_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573964.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12068..12184
                     /locus_tag="J8R83_000817"
     CDS             12068..12184
                     /locus_tag="J8R83_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAZ9573965.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13112..13450
                     /locus_tag="J8R83_000818"
     CDS             13112..13450
                     /locus_tag="J8R83_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573966.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13544..13774
                     /locus_tag="J8R83_000819"
     CDS             13544..13774
                     /locus_tag="J8R83_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573967.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14174..14545
                     /locus_tag="J8R83_000820"
     CDS             14174..14545
                     /locus_tag="J8R83_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAZ9573968.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14819..15511)
                     /locus_tag="J8R83_000821"
     CDS             complement(14819..15511)
                     /locus_tag="J8R83_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9573969.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15514..16299)
                     /locus_tag="J8R83_000822"
     CDS             complement(15514..16299)
                     /locus_tag="J8R83_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9573970.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16536..17936
                     /gene="lacG"
                     /locus_tag="J8R83_000823"
     CDS             16536..17936
                     /gene="lacG"
                     /locus_tag="J8R83_000823"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAZ9573971.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17961..18278
                     /locus_tag="J8R83_000824"
     CDS             17961..18278
                     /locus_tag="J8R83_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9573972.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18291..19964
                     /locus_tag="J8R83_000825"
     CDS             18291..19964
                     /locus_tag="J8R83_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9573973.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19978..21609
                     /locus_tag="J8R83_000826"
     CDS             19978..21609
                     /locus_tag="J8R83_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAZ9573974.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22100..23665)
                     /gene="guaA"
                     /locus_tag="J8R83_000827"
     CDS             complement(22100..23665)
                     /gene="guaA"
                     /locus_tag="J8R83_000827"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAZ9573975.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23724..24647)
                     /locus_tag="J8R83_000828"
     CDS             complement(23724..24647)
                     /locus_tag="J8R83_000828"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAZ9573976.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24843..25448
                     /locus_tag="J8R83_000829"
     CDS             24843..25448
                     /locus_tag="J8R83_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9573977.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25647..26666
                     /locus_tag="J8R83_000830"
     CDS             25647..26666
                     /locus_tag="J8R83_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9573978.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKAS"
     gene            26762..28063
                     /locus_tag="J8R83_000831"
     CDS             26762..28063
                     /locus_tag="J8R83_000831"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAZ9573979.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28109..28771
                     /gene="deoC"
                     /locus_tag="J8R83_000832"
     CDS             28109..28771
                     /gene="deoC"
                     /locus_tag="J8R83_000832"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAZ9573980.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28792..29190
                     /locus_tag="J8R83_000833"
     CDS             28792..29190
                     /locus_tag="J8R83_000833"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAZ9573981.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29256..30338
                     /locus_tag="J8R83_000834"
     CDS             29256..30338
                     /locus_tag="J8R83_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9573982.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30550..32112
                     /locus_tag="J8R83_000835"
     CDS             30550..32112
                     /locus_tag="J8R83_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9573983.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32105..33238
                     /locus_tag="J8R83_000836"
     CDS             32105..33238
                     /locus_tag="J8R83_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573984.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33238..34194
                     /locus_tag="J8R83_000837"
     CDS             33238..34194
                     /locus_tag="J8R83_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9573985.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34293..35459
                     /gene="deoB"
                     /locus_tag="J8R83_000838"
     CDS             34293..35459
                     /gene="deoB"
                     /locus_tag="J8R83_000838"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAZ9573986.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35483..36301
                     /locus_tag="J8R83_000839"
     CDS             35483..36301
                     /locus_tag="J8R83_000839"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAZ9573987.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36318..37025
                     /gene="deoD"
                     /locus_tag="J8R83_000840"
     CDS             36318..37025
                     /gene="deoD"
                     /locus_tag="J8R83_000840"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAZ9573988.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT        11593 a         6494 c         7859 g        11214 t
ORIGIN      
        1 ccacttctgt cacaacctct tattttgatt agaacttgcg aaaataaacc ggttaaagtg
       61 tgtctagcgc aagagatttg ctataataga cgataagggt aaaatgtaac gagaaggggt
      121 tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga tctgccatac catgtattag
      181 caaaagaaaa agttgatttt ttatcaatga atctccaatt gaatgatcaa gagttagtag
      241 atgacctcgg aaagacattc aattatgacc gctacatgaa tcagctgaaa aatggtgcga
      301 tgcctacgac atcacaaatc aatgttggcc gatatttaga atttttccgt tcttatgcgg
      361 aaaaacagat tcctgtttta tatgtggctt tttccagtgg attaagcggc tcttacagta
      421 gtgcgcttca agcggttgaa ttgctgaagg aagaatatga agaccctgag atctatgttt
      481 ttgatacaaa agctgcaagt attggggaag ggcttttagt attggaagct gtaagattga
      541 aaaaagaagg taaaagcatc gaagaaaccc tagagtggct ggaaagtaat tatttgaaag
      601 tccattcatg ggtaacagta gacgatctga aatatctaga acgaggcggt aggatttcca
      661 aagcaagtgc tactcttggc agtctattga gtgtaaagcc tattattacg gtggataaag
      721 aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa caagtcgatc cagacaatcg
      781 tcaatgagac ggtaaaaaca atcgttgcac cacttgatca aatcgtttat gtggcttacg
      841 ctggggatct agagagcgcg gagaaggcaa aacggctttt ggaagagcag ataaagatga
      901 aagatgtgaa gctttatccc ttaggaccaa cgatcgccag tcacacaggc tatggctgta
      961 tcgcgatttt ttcgatggga atcagtcgat aaaagcagta actcattctg taaaaaagcc
     1021 cagaaattga ttgtaacaaa aacagcgact cttaaaagat agatgagcat cctatctctt
     1081 agaggtcgct gtttttttat tttttaagct aaataggcca ttatgcccat aactcgttca
     1141 attgtttttg aatatctgca ttttccaaaa attcatcata tgtcgtatca gctcgatcga
     1201 tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa tgtttggata aattgatggt
     1261 catgtgacgc aaataagatt gagccagtaa atgccatcaa gccgtcattc aatgctgtga
     1321 ttgattctaa gtctaaatgg ttcgttggat catctaatac aagtacgtta gctttcgaaa
     1381 gcatcatttt tgaaagcatg caacggactt tctctccacc agataaaaca ttcactggtt
     1441 tcaatacttc ttcaccagaa aacaacattc ttcctaagaa gcttcttaag aaggtgttat
     1501 catcttcttc tttacttgca tattgacgca accagtctaa aatcgttaga tcagtatcga
     1561 attctttcgt tgtatccttt ggtaaataag aattacttgt tgtcacaccc caacgtactg
     1621 ttccagtatc tggcgtaatt tcacccatga taactttgaa tagcgttgtt gttgttatat
     1681 cattttctgc gacgaaagcg accttgtctt ctttgctcaa attaaaagat atatcatcta
     1741 aaattttctt tccatcaatc gttacactta cattttctac ctgcaataag tcgtttccaa
     1801 tctcacgttc aggtttgaat ccaacgaatg gataacgtct agaagaaggt tggatatcgt
     1861 ctaaagtaat tttttcaagc atttttttac gtgaagttgc ttgttttgat tttgatgcat
     1921 tcgcactaaa gcgggcaata aattcttgga gttctttgat ttgttcttct tttttggcat
     1981 ttgcgtttgc ttgaagttta gccgctagtt gactagattc caaccaaaaa tcataatttc
     2041 ctacataaag tttgatttta ccaaaatcta gatccgccat atgtgtacat actttgttca
     2101 aaaagtgacg gtcatgggat acaacgatca cagtattttc aaaattgatc aaaaattctt
     2161 ccagccaatt gatcgattgg atatccagac cgtttgttgg ttcgtctagc aaaagaacat
     2221 caggtttacc aaatagtgtt tgtgctaata acacttttac cttttgtcca ccagttaatt
     2281 cactcatttg ctgatggtgc aattcttcag ggatgttcag accttgcagt aaaacagctg
     2341 cttctggttc agcttcccat ccattaagct cagcaaattc tccttctaat tcagctgctc
     2401 gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat cgcatctttt tctttcagca
     2461 cttcatacag acgcttgtgt cccatgatga ctgtttcaag tacagtatag tcttcatagt
     2521 cgtaatggtt ctgtttcaat acggccatcc gttcatctgg tcccatagta acggaacctg
     2581 tggaaggctg cagatcccct gataacactt taaggaacgt tgatttacct gcaccatttg
     2641 caccaatcaa gccatagcag tttccggggg taaatttaat attcacatca tcaaatagtt
     2701 tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat caattttttt cctcactttt
     2761 atcattatta gttttgacaa gtcttataga attatatagg ggaaaggtaa aagattcaag
     2821 gcaatcgaac attctttgtg tttcacgtga aacagaatga aaaaaataaa aataaaagcg
     2881 gagcgaaaat agctactata ggatttatta gtttgcaaca gcataatttt tgacgttatt
     2941 tataagaggg agtactataa aactgtaaaa gaaatgaaag aaggattgaa aatggatgaa
     3001 aaaagaacca tcgactgggg ctcattgatt ttgggaattt tatttgtact tgtctcattg
     3061 ttatcatttc aagaccctgt cggaaattta gttgcaattg tagtagtctt tgcgattttt
     3121 gcctttatta aagggatatt tgaactgttt gtacggaaca gattaaaaga gctaacagga
     3181 tataaaggaa agatgccctt aataatcggg atcatcgata ttctagttgg cgtctttttc
     3241 ttattcaata ttggtgcagg agtcgcagca ttgccttttg tttttgcagt atggtttatt
     3301 gctgattcag ttttagcgtt atttactgct gacttggcaa gaggagtaag tgaaggatat
     3361 tattggttta cgatcatcgt caatatttta ggaattttat taggaatttt cttattgttt
     3421 aatccaattt cttctgcgtt gacattaagc tttttagttg gattctattt tatgttattt
     3481 ggtatcacac atatcgtcta tgcatttaga taagtaaaat caaacaaata aaaaagccgg
     3541 cttccgatta cagttttact gttgtaattg gaagccggct tttttatcat ggacaaatat
     3601 gcacgaggtg atttttaggt gtcgagacaa atttatgcaa aaatgtgaga agctatatac
     3661 acaaatttta tcttaatact cgaagcatag cgcagttgtc acaacctctt ttcatataat
     3721 tcattcaata ctggcaaatc atggacttca tatttttctt tgaatgcttg gatttcttct
     3781 tcagaatatt ttcttggatc taaatgcaga tcttctactg gcaatgggcg cttgttattg
     3841 atcttcacat cgattactac aggacgatct gattttgcag ctgcatcaaa ggcaaatcga
     3901 agttgcgagt attctgtgac tgtaaagcta tttgccccga gcgcttctcc aactttaccg
     3961 aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt ccgtatcttc ttgttctgct
     4021 tcgatgaaac caaaagaatc attcgaaaag acaacattaa taattggaag ctgatatttg
     4081 acttgtgtaa tgatatcttg catgaccata gcaaacccgc catcaccact taaggtaaat
     4141 acttgttttt ctgggtagct tagttgtgcg gcaattcctc ctggcacacc attacccata
     4201 gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt tcatattcaa taaacgaata
     4261 gaatggatag tcgtgttacc gacatctgtg acgaaaatcg catcgtcttc agcaatacga
     4321 ttgatttctt tatagacagc ctctggacga atcggttctt cctctcgatc ttcaaaagat
     4381 ttcaaccaat ttacccattt ttctttattt tcttgatttg ctaggtacca gctatcagca
     4441 gggcgagcat cccctaactc gacaagtctt tgcaaagctg tgtttgcatc accgaggatc
     4501 gacaaagatg tttcatggcg tcgtccaaat tttgacgcat cgatatcgat ttggataaat
     4561 tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt cgctaccgac aaataagatc
     4621 agatcggctt ctgccaatgc ttcatttccg ggtttagtag cgacacgtcc agcaaaacca
     4681 agaaagtttt cataatcatc aggaataatt ccttttgcta gaacggaagc gacaacagga
     4741 actgaaaaat gttctgagaa ttctttgatt tgcggaaatc cgtttcgcgt tccttgacca
     4801 acataaagaa ctggtttttt tgctttttca agataaggca aagcagctag caaatctttt
     4861 tcttctggta atatcacact tgttttgtga gtgtgagcgg tggagaaagg ttgttcgtca
     4921 atttcttcaa aaccaagatc aacagggata gtcacgatag ccacgccttt atgctcatag
     4981 gcggctttaa tggcttcatc tactacatgc ggaagacttt gtggtgtcat gactgtacga
     5041 ttgtatacgc taacatctgc gaaaatagga ttttcattta gttcctggaa agagttatag
     5101 ttcatggatg tagaagcaac ttgtcctaag aacgctacta gaggcacatg gtccatctgt
     5161 gcatcataca aaccattgat caaatgtgtc gcaccaggtc ctgcagagcc gaagacagcg
     5221 ccgactttcc ccgttaattt tgcatctgca gcggctgcga gtgcgccgac ttcttcatga
     5281 cgaacttgaa tgtagttgat ttcggttttt tcttgatata gcgcatccat aattgaattg
     5341 aaagatcctc cgggaatgcc gtaaatatgg tcgatacccc agctttcaag aacttttacc
     5401 attgcgattc ctgcattgat ttttgacatg gtgtttcact cctttagcaa tgatgataca
     5461 taaatttttt gtatctagag tatagaactt tttatcgaaa atcccaacta attcgtcttt
     5521 tcacaaaaat gtagtcatgt ttttgggaat atgctagagt agtacataga tagattcaag
     5581 agaggggaat ggcatggttg aatggctatt gagacttgaa ccttggcagc aagcacttgc
     5641 tgggacagct tttacttatt ttatgacagc tcttggtgcc gggttggttt ttttctttaa
     5701 agaaatcaaa aaagaagtgc taaacttgat gttaggattt gcttctggtg tcatgattgc
     5761 tgcaagtttt tggtctttgt tagatccggc tattacaaaa gcagaagaaa atggagatat
     5821 tgcttggcta gttgtaagta ttgggtttgg tttaggcggt gtgtttttat atatggcaga
     5881 taaaacactg ccccatatgc attttggacc acaacatgaa gcagaaggat tgcctaccca
     5941 tttaaaacgg acgatcttgc ttgttttttc tattacattg cataacattc ctgaaggttt
     6001 agccgtgggg gtagcattcg gtgcagcagc aactgcggat aatccgacag ccgctatatt
     6061 agccgctgtt tcggtggcgc taggtattgg tatccaaaac ttcccagaag gagcagctgt
     6121 atcaatcccg ttgcgacaag aaggtctgag tcgtaaaaag gcctttgttt acggacaagc
     6181 ttctggaatc gttgaaccaa ttgctggagt gattggagcg ctactagtaa cgaaagtgga
     6241 gctgctgctt ccttatgcac ttgcttttgc cgcaggagca atgatttatg tcgtggtgga
     6301 agaattgatc cctgaagcac agcagacatt gtccagcaaa cgtcattttg cagtttttgg
     6361 cgtcatgagt ggatttatca ttatgatgat tttggatgtg gcattaggat aaataaaaaa
     6421 aatatatatg atatatcaaa tagggccgcg aacttatatc gcgaccctat ttttttagta
     6481 agttatatca taatgaagtg aatggtatca tacattaata atagtttttt ctatgtgtat
     6541 ttcctttgat ccagcgaaca agccagatga taagtgcgat tgggattaga actttgaccg
     6601 caaaccataa aagcccgctt aggacactga caaaaagact gatgacgaag ctagctgcaa
     6661 ttagcactaa aagaaccatg aagatattta agaacatatt tttttgacgc atacaaaacc
     6721 ctcctcttgt tcattcttta ctatagaaaa agtataacag ggattgttta aaaacacctc
     6781 caactgaaga ctgattttta cttcatctac ttaaatgatc aaacaattgc tttttctctg
     6841 gtttatcatc taaaatagag cggaaaagga ggagaatatc atgcctaaaa atcgtcttga
     6901 agcatttaca gatgctgtaa tcgcgattat catgactatt ttagttttag aacttcatga
     6961 acctaacgga gacacgtggg aggcgctcgc tgcattaggt taccgatttt ttatctatat
     7021 tgtcagtttt atcattttag cgatttattg gaacaatcat catcatttat ttcaagttgt
     7081 acataagata aatggacggg tcttatgggc gaacagtttc tttgtttttg cgctttcgct
     7141 ttttccgttt gcaacttcat ggatcagtga gtacatcaat agcctggctc cagaaatgac
     7201 ttatggtttt gttaccttga ccgctaatat tgcgtattat atcttggcaa aagaacttgt
     7261 caaagcaaat aaaggccacg agaaagcatt gaaggcgatg ttgaataatt acaagaaatc
     7321 gtatctatcg attggtttga atgtgttagg aattgtctta gggtatttag tagcgccagt
     7381 agccgtgctg atcgcaaaca tcgtgattct agctgcttgg atcatcccaa gtcgtaccat
     7441 cgaatcacaa tatcggtaaa atgatccgtg tttaaaattt aagagaaaaa tatagaaaaa
     7501 ataaataaac gatcaaatat ccgagtgata ctagtattca aagagggatg cagatggatc
     7561 aaaaaagaat tcatgtagga ctgattacta gttttgtcac gatgcttatt tatttggatc
     7621 aaggtcattt gacttggaca gtagttggtg tcgtaggatt tttgacatta ttcacagcaa
     7681 taaaaaaata aacatcttta tgtaatctga tgttctatct atttaagaaa agcatgttta
     7741 cagcagtatg attctgttgt aaacgtgttt ttatttgtgg aaaatttaat ttttagaaaa
     7801 gtgtatcgaa aaatagatag ttagtttttc cacagtggat aacttcgtaa gagataaaaa
     7861 taaaaaatta gtcaaagaag ggcgtataga tttcttttga taggagatat acaacagaaa
     7921 tgaataaata ttaacgtgtt ttcaaacagt ataaaacggt gtggtttttg gaataaaaaa
     7981 ataacatatc tcattttaca cttttgttat tttatactta aaaaataacg acacagaaaa
     8041 taccgtgtct cagatttctc tactacttct aaaaactact gtttttttcc tttgaaatgc
     8101 cttcaaaaag taggatcagg cagaatatac tggcagaatc aaggagaagg gagcctaaat
     8161 aaggagaaaa accatagaaa atataaagta attacttata aaacaagctt tttatagaaa
     8221 aataatatac ctgagtaggg tataaattaa gacggaattc ctttctagat tgagatattg
     8281 actaggaaga atgttaagat tttaagcctt taagctaaaa aaaaaccctt tttgttaaat
     8341 aaggggaata tagcctgtca gtttcaaact gcaagtcgtc ctgctgcaat aatatagtag
     8401 attagagatg aaaatagatt tttttaaacc aatgactgaa taaaaagacc gtcatagata
     8461 cacattggaa tgtgtctatt acggtctttt tttacgaacg attttattga agacggacag
     8521 ttcgggtcaa aaataaaaaa gctacgatca gaaataagaa taaaatgtat cccaaaataa
     8581 tggctagacg gtctaactta tttgtcgata gatgtttgtt tagaagttga taggcccata
     8641 aacctatcag tcctcctgtt gtattagtta tcaaatcagt gatgtccgct acgccaatac
     8701 cgaataggaa ttgaatcaat tctgccaaga agcttacaag gaaaataatc cctaattttt
     8761 tagaaaaaga aagtctcttg aaattgacat tcaaaagcac cccaaaagga aaaaagacaa
     8821 tcaagttata agtggtctca cgtaataccg tcgtattttc aaaagaaaaa gtagaaaaag
     8881 ggacgagatt gacattgctg taagaataag tgagaaattg tggaagatta aatgatagct
     8941 tgaataaaat caaccataat agaaagaata aataaatccc taataaaaat tttgatacat
     9001 accgcataga catctcctcc atttaaaaag tataccatcg aaaaccgctg aaaaatcata
     9061 aaaaagtatg aagtttaagg accaacgtag ttatcgtacg aaaattagaa gctttttttt
     9121 gttgggaatc cggtttcttt aacaaagcta agatagcgag ttgcttggaa aagttgctat
     9181 cttttttctg tcaaaacgac tcggaatgtt cgttttttgt tctaatttct ccaagttgtt
     9241 tactttttga tactaagttt atgaaaaatc aagaaatagt tgttatacta ggtaatgctg
     9301 acaaacggga ttggcatttc atcttggttc agcttttttt ccaattacta ggaaggaggg
     9361 atagattgtt caagacttat tttcgtttca ataaaataca agataatcct tttcgtatca
     9421 tgaatctgat gctacttatc tttattgtat tatggttagg ttacataaat catgattttt
     9481 tgatttcaag tttttcatca ttagggatct ttactttttt ctattatcaa aacataccga
     9541 tgaaatattt gctgaaacgt atgtttctga tcggttgcgg actgttggtt gctttcgttt
     9601 tggggatctt atcgacttat gttttatggc ttgaaccatt tgccgtagct ttggttgctt
     9661 tttccagcag attcgtgttg cgattattcc atatttctaa accaggtggc ttgttttttg
     9721 cgatgctttc tgccatggga acgagcatgc agctgccaat cgctcaatta ccgatcgtct
     9781 cactttattt ttttatgggt gtcgtttttg ccctgattgc ggcagtgatt acaaaattac
     9841 tggattcacg gcctgagcag acaattgaaa aagcaacttt aaaagaaaga tttcacgaag
     9901 agcctttagt gatcattgat tctgttttct acagcgctgc cttatttctt tccgtttatg
     9961 tcagtcacgg cttgaatctg cataatcctt attggttgac cttgtcatgt gcatcgattt
    10021 tgctagcaga aaacttggat gcgatgaagc atcgacaagt ccaatatctg attggatcga
    10081 tgggtgggtt atgtgtgtcg gcattcttgt catttgtgcc gtttacgcag ttgcagacca
    10141 tttttctgat cacttttcta tatggaatcg cacaatttct agttgctaga aattatgcag
    10201 ttgctaatat ttttcttaat ccgatggcgt tgatgctatc tacacttatt cgtggagcat
    10261 acttgatttc tttgatcgaa tatcgttttt tagggatcgt cataggaagt ttcatcggtt
    10321 taggtgttgc gtgggtaatg acggttggtt tgcaacatta tttaacggtt gttcgtcaaa
    10381 aattagaata gaaggacaaa tatatgtgcc aaaagaggtt atgacaagat ttttgtcaca
    10441 acctctaatt caaggtgttc aaaagccaga ttctcagcat taagtcaaat tcacacaaaa
    10501 atgtggaaag gaactttcaa aaaaatttta tatttattct atcaaaaaat tttgtttatg
    10561 atggtaactg aataaacttt cctgagatgg tcaatgcttt ccttgaaagt cttacagata
    10621 ttctttcttc atagaaagtt taagttttat agttagtgta caataaaagt atgtttatac
    10681 catatggtgt ccggataatc agtcatttaa acaatgaggt tcaaagatat gaaaagggga
    10741 aatttgatga agaaaataag caatgaaatc caaattctgg cagaaacttt aactcttccc
    10801 aaagtcgtta tagagcaaat gattgtacaa gcaaaaaaca tccttgatga ggtgtttgag
    10861 caatatagtc atgaactaat ggatcctaat aaagcaaagg cgactgcaaa gaaaatagac
    10921 aaagtctatg aagaggaacc ttttgcagca ttagctattt atctatatgc agcttctcaa
    10981 agttggaaaa aaatttatca accattgaag attccaagaa ctatctattt ggcaacaatg
    11041 aatgctttta ctagatttat tcatgaacat ttccaagtaa caggaagcta tcgctttgac
    11101 cgtggttttt ggatttggca ttacactagt ggcttgatct ttcggattgg tgaattggag
    11161 tacgaaatga catattttcc gaaagggtac acggatctaa gattagaagg aaagcagtgc
    11221 ctttctcttc atattccttc cgatgcagat ttatctcaga ataagataag agatagttac
    11281 gaaagtgcca ttcgtttttt tgaactttat tttcctgatt accattacca agtgatgtac
    11341 acagatactt ggttactatc acccaatctt actaaatggt tgaaaaaaga gtcaaaaatc
    11401 tgtctttttg cagccgatta tcgattatta tcagttgatg aacaggacga tagtggagtc
    11461 ccttggatct ttggacgagt agatgcccaa atacatgatt atccagaaag tacgagttta
    11521 cagcgacaag caaaagagca attgcttgca ggcgagcaca ttggctctgg cttaggtatt
    11581 cttacttcat aagtttagta cttcgaaata gtttaaaaga gcgtgagaca aaagtaaaga
    11641 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcagaagca actccttcgg
    11701 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct
    11761 tggagttaaa cgcttctgtc ccagcctctt ttttagtgtt ctatcgaaca cacagtacgt
    11821 tcaataggta aactagctat aacaatagat attaaagtta acggacaaga gggccttttt
    11881 taggtagcta aaacgtaata atgaaaattt atttccagag ataggagtca atcagctagt
    11941 ctgatcgact gttttaacaa gttgactttc attttaactt ttgataccat ttaaaacaca
    12001 aatcgtaatt gtttcgattt gtgtttttta gcatgactac aatcaaagaa gaaagtgggt
    12061 cgtccatatg gaaaaaacag atatctcaag tgcataccgc cgcttgaaaa gcccaaatat
    12121 caaaacacga aaacgtgcgc tgaagatcat caaagatgtg aaacggaata gtgggaaaag
    12181 gtaagaagaa ggaaacttaa ttaaaaaaat agccgaaaaa cgtttttcgg ctattttcaa
    12241 taatcggttt ttgtgtaagg tttccgaaag aactgctgtt gattttccat ttttaacata
    12301 tgataaattg gtagaatctt tcttttcaaa ttgataccat tccctaattc cagttatata
    12361 gttaactaca gaaccacaaa gcacgtacgt ttataaaagt attatctgta gttatttttc
    12421 aattcccttt caacctctta ttttgaccag tagtattgat cactttacct tttaacacct
    12481 ttgttcgttt ttgaaacatt tttagtcaag aatggaaacg taactacata atcaaaggtt
    12541 ttgcgaaata tttcatgaaa tatttcatgt agaagcgagc aatacggttg caaataacca
    12601 ttatcgttta ataagcagtt acgaaagctc ccaatatctc taacgttcag ctcactccat
    12661 ttcttttctt caaaaaaatc agtgattcgt atctctttct atttgtcgaa aaagttaact
    12721 ttaaaaagta acgccgaaaa aatatgcaaa aaaataaaaa agcagttact attgctagaa
    12781 taacatcaag gaataataag ttttggtttt cagataatag tcgataagtt gtgtattgga
    12841 attttagata cagtaataaa gtatttttca tgaaattttg tgagaatcac tattacaagt
    12901 atctttaata aaattaatgg ttaaggagga acttaaagta gaatgtaaat gaatagttgt
    12961 agtcagtcga ttgtgatact agactcaaag ttgcaggaat aagtttttca atttgtgatt
    13021 ggaagataaa aaatgaaaaa gaagggcttt tttttatact ttgttgattg tagtgtttat
    13081 tttccctctg tttagccaag taacattttc tatgactcaa ccagtttcaa gtgaggaaca
    13141 tgataacctt tttcgtgcta cagaagagtt taagaaatat caggaaaata ttgttccgga
    13201 gactccatta gctagtgagc caattactga tattgatgga aaccaaatag gatggtatat
    13261 acagtacgaa gttatggtgg taaataatga ctcaatagta aaaaatacag taggcttaga
    13321 gctaacaccg attgaaaagg tgagttcatt gttaacgtat atttatactg atgaaagtga
    13381 cgagactgag atcattttaa cggattactc aaaaattgct actgataaaa agtatatatt
    13441 gtggatgtag acactagtga aatactttat gatatagaaa ttgatgaaaa tttactagat
    13501 gtagcacaag aaatcgatca tcaaaagcag gaagctattc gatatgctgg tagaaaaggg
    13561 aaaagaaaat atttattacg tgaatgtagc aaaagttaga gaagatgaaa atgagtggaa
    13621 agaattcaag agtcgctact caattaactc gactccgaca tttacagttt acagagaagg
    13681 atcgatagaa aaaactgttt tttggactaa agaaagtgga atgtctttag ctgaagtaga
    13741 agagtttttg gattatgtta gtatgcaaca gtaagggagt tcttattatg aaaaattttg
    13801 acacatatta tgttattgtt ttttcgatat ctttgctgtt aatattacta actttaatgc
    13861 agtataaaga gtatccagag tattttattt taacttttgt atatttagta agtagctaca
    13921 cacttctata taaattcaga agttcttcta gagtttctaa agtttgtttc ttaattagct
    13981 tattgattct ataatatttt tgatttatat aggaaattaa aaatattata gaatcaacac
    14041 tcagagaacg ggttggtttt taatagattt aataagtact gataatgaaa tttctcctgg
    14101 ttgggaaaac gaagttggtt accctgtaga agaatttttt caagattact ttgcggagta
    14161 tgccgatagg ataatgagag attacgtaac agataaaact caagaagtca tcaatcaatc
    14221 ccagtcatta aatgaattat ctgataaggc gaaagaagaa gcagttgcca ttatttcttc
    14281 agggattagt gactatattg atatgagtgg tgaaatcaat tatggcgata aagacaaaat
    14341 tgtacgcatg ataaaagctt ttatcaaaac ttttgatgtg aaggcagatc ttaagtttaa
    14401 tgatacttac ctagtaggaa aattaattaa tatccttggg acagagaaag atacggaaac
    14461 gtttatttcc tctttgtcta tgttgtttac agataagcat ttttcaactc agcttggtgg
    14521 agaggaacta gtggaaatct tttaaccatt acgcccagca ttaataaaag tatatcaaaa
    14581 aagtactcct gatgattttt aagattggtt tgagaaataa tgtgaaaaca ctatttttaa
    14641 tgttaattat agatagagat gaacgcgtca tatggttaaa agaatgaaaa agtcaaagat
    14701 acactgctat atttcactaa ggatatagca gtgtatcttt catgtcgttt cactggcagt
    14761 tttttataaa aggaggtgtg catttcagtt gcttttcttt ggtagttagt tgaatcgttt
    14821 aagaattaac ggatgtggca gacaggtgct ctgtccaaaa accagtaaaa tctttgatgg
    14881 ttccatcttt atttagctgt gcctgttcaa atactgtttt gtttttaccg aatggatcaa
    14941 ttgcaataat tgttccgatc cccgcacgtt tggcagcaag taatcctgag taagcatctt
    15001 cgataacaag acaatcagcc ggagctaagc tcagtttgtc tgccgcttta agaaaaatat
    15061 ccggttgcgg tttcccaggg aaagagccgt cgtcatagac aatcttgtcc cagtcaaacc
    15121 agcgggctaa atcgaaaata tcaaaataaa aagcaacatt ctctttgaca gtagccgtgg
    15181 caatcgttaa tggaatctgt tggtcagtca gctggtcaag agtcgcttca agcccttttg
    15241 tcaactgaag ctcgttttca ttttgcaagc aaagcatacg ataatagctt tctttttctt
    15301 ctgacaatac ggcgatctca gaggcggtca aatgctctga aatgaaatgt ttcaaaatct
    15361 ccgtattcgt ccgaccatga atatttttta aaatatcctc gtctgataaa ccatcttttg
    15421 tatgatcatg tatcatatgc agccaagcag cttcatgcag atgagagtcc aaaaacattg
    15481 ttccgttgaa atcaaatata atccctttca tagttacgct cctatagtgg tattttcggt
    15541 tgaatcagca atttgcagat cgacatattg tgcatagtgc tcttgaacct cccgcgagat
    15601 ctggcgatcc gtaatgagca gatcgaaatc atgcaaatta taaaacacat aaaaatcatc
    15661 tcgattgaat tttttattat caacgagtag atatttctta cgggaattat ttagagcgat
    15721 ctgctgtgct tctccttctt cggtactgta agtagagatc gcttcgttgt gaacgccatt
    15781 tgaactgata aatgcttttg taaactttag tcttcttaaa ttgtcgttgg tgatcggtcc
    15841 gacaaatgcg ccggtatttt tccggaaatc accgccaatc agtagaattt ctggtccatc
    15901 tgcttgagca agaatatcaa aaactggata attatttgta atgatccgaa ttttcttgtt
    15961 cagtaaatgc gtcgccaata gttcgattgt tgtacctggt cctaagaaaa tcgtttctcc
    16021 ctcgtgaatc aaggaggctg ctgtggcagc aatttctttt ttttcttgaa tctgcagagt
    16081 ggctttttca gtgtgagaaa gttcttgatc taaagtgtag gaaagacttt gagcccctcc
    16141 atggacacgc agcagcttgc ccgatttttc taattcatct aaatctctgc gaacggtcat
    16201 atcagaaaca tctaattgat tgatgatttc attaacggta aggattcctt ttttattgac
    16261 catttctacg atagtaagca atctttcttt tttcaacatt gtcttcacct ctaatttaag
    16321 gataatctat catataaacg gacaacagtc aatctaattc gaacaaaagt aaacatttag
    16381 ggtggttttt atgtttgtta caatagattt tattgctgtt ttctggtttt tatgattatt
    16441 tgtgtttgtt tttgttgaca aatgttttgg atgcgtttac aatgcaatca gttagaaaga
    16501 gcgaaaactg attatagatt tgaggagaga tgtacatgct taaattacca gaagatttta
    16561 tttttggcgg agccacagca gcctatcagg ttgaaggagc cactaaggaa ggtggcaaag
    16621 gcgctgttgc ttgggatgac tttttagagg aacaagggcg attcagtccc gatccggcaa
    16681 gtgattttta tcatcaatat gcaaaggaca ttgaattgtg tgaacgtttt ggtgtaaatg
    16741 gtctaagatt atccattgct tggagccgca tttttcctga tggagctggg aaaccaaatc
    16801 cagaaggaat cgctttttat catcgtgtgt tcgaagaatg taagaaaaga aacgtaacgc
    16861 cgtttgtgac gttgcatcat tttgataccc ctaaacgttt gtttgaccat ggagattttt
    16921 tgaatcgaga aacaatagaa gcatttgttt cctatgccat tttttgtttt catgaattca
    16981 aagaagtcaa ggtgtggagt acctttaatg aaatctatcc agttgcaacc aatcaatatt
    17041 tgttaggtgt tttcccacca ggaatcaaat atgattttac aaagatcgtc gcctgtcttc
    17101 ataatatgat ggttgctcat gcccgtgtag tgaactattt caaagaaaac gaacttccgg
    17161 gtgaaattgg tgtagttcac tcattagaga cgaaatatgc ggcaacagac gcgccggaag
    17221 ataagcatgc tgccttttta gacgatgcat tgtcgatccg tttcttatta gatgctacct
    17281 atttaggcta ttattcaact gaaaccttga ctgctcttga tgagatatgt gaagcaaatc
    17341 aggccagcta tcattttcct gaagaagatt tcgttgaatt gaaaaaagca tccacgcgta
    17401 atgactactt agggatcaat cactaccaat gccattttgt caaagcttac gatggagaaa
    17461 atgcaatcca tcataacggt acgggtgaaa aagggacctc tgtttataaa gtgaagggaa
    17521 tcggagaacg tatttataaa gaaggaattc ctcgaactga ttgggactgg ctgatttatc
    17581 cagaaggtct atatgacttg ttgctgcgaa ttaaaagcga ttacccacat tacaacaaaa
    17641 tctatatcac tgagaacggg atggggtata aagatcagtt tgaagatggc attattatgg
    17701 atcagccgag aatcgactat ttgagagtct atttggaatc cttaagcaag gcgataacag
    17761 ccggggtaaa tgtgaagggg tattttttgt ggtcgcttat ggatcttttc tcatggacaa
    17821 atgggtataa caaaaggtat ggcttgtttt atgttgattt tgaaacccag aagcgttacc
    17881 caaaagaatc agcttactgg tacaagttgg tcagtgaaac caaaacgatt atttaataag
    17941 tgataatgga ggaagaaaag atgaataaag aggaattaca aatgcttggt tttgagatcg
    18001 ttgcatattc aggcgacgct cgcagtacat tattgaaatt attgaaagaa gtaagacaag
    18061 gaaactttga acatgttgat tcggcgttga aagaagccga cgaaaattta acccttgcac
    18121 ataattcgca aacaaaaatt ttagcggaag aagcatctgg gaaagagatg gagatgggat
    18181 tcatttttat ccatgggcag gatcatttaa tgaccacttt attgctgaga gatctgattc
    18241 aagactttat tgtactgtac agacagaatc aaggatagga gaagaacgct atggatggaa
    18301 tcattaaaca aatcgaaaaa gggaaaccat tttttgaaaa aatctcacgt aatagttatt
    18361 taggagccgt tcgtgacgga tttttaacag cgatgccagc tattttattt tcaagcattt
    18421 tcattttgat tgctgcggtt cctgagattt ttggttacca atggcctgaa tctgtctcca
    18481 catggctatg gaaagtctat aattattcga tgggtgttgt agggttactc gtttcagcaa
    18541 ccactgctcg ctgcttggct gattcgatga atcgtcgctt accgaaaaac aaagtaatca
    18601 acaccacctc tgtgatgctg gcctctgtgg taagtttcct gttgttaagc gtctctccga
    18661 ttgaaggtgg attttcaacg gaatatatgg ggacaaaggg actactggct tcctttgtcg
    18721 ctgcattttt aacagttaat ttatataagt tttgtgtgct gaaagatatt accattaaaa
    18781 tgcctaaaga agttcctgga acgatttcgc aaaccttccg agatattttt cctttctctt
    18841 tttcagtatt tgcggccgtt ttaattgatt taggcattcg acaaatcttc caaatctcat
    18901 ttgcagaagc aatcattacg gtgctgcagc cgctatttac agcagctgac gggtacttag
    18961 gaatcgctat tatctgggga gcgatggcgc tgttttggtt tgtcggtgtt catggaccgt
    19021 cgatcgtgga gccggcaatt gcggcaatta tctatgccaa tgtggaaacc aatctgcaat
    19081 tgttcaattc cggtgaacaa gcttctaaag tactgacggt gggtttaggg aattttgtag
    19141 gaactatggg aggaactggg gcaacattgg ttgttccttt tatcttccta ctctttgcta
    19201 agtctaagca gttgaaggca gttgggaaag cttcctttat tccagtaagt ttcgctgtca
    19261 acgaaccatt gctatttgcg gcacccatga ttttgaaccc ttattttttt attccatttt
    19321 tgttaacacc tgttgtaaac gtttgcctgt tcaagttttt tgtcgatgta ttgggcatga
    19381 acagctttat gtacgttttg ccttgggcaa ctccagcacc gatcggtttg gttctaggaa
    19441 cgggcatggg tatcttagct tttgttctag cagcggttct aatcgtcgtt gacttcctga
    19501 tctatctacc attttgcaaa gcatacgatg ctgtcttagt agagaaagaa gcacaaaaag
    19561 cagaggtgat cgcaaccgag gaaggtgctt ctgccgatgt acgtgaggaa gtacctgtgg
    19621 cagcgagtca agttatcagc gatgcaaata aagaaatcaa tgtgttggta ctttgtgctg
    19681 gcgcagggac aagtgggatg ttagctaatg ctttaaaaaa aggtgcatct gaatcgaaag
    19741 caccgatcag tgcaatggcg ggtgcttatg gttctcatta cgaaatgctg caggattttg
    19801 atatggtggt cttagcaccg caagtcaatt cttactatga tgatatcaaa gaagacaccg
    19861 atcgcttagg aatcaagctg gttgcgacaa aaggagcaga atatatcgga ttaacgagag
    19921 atcctgaaaa agctgttcag tttattctga accaatttca ataaaggagg agccataatg
    19981 aaaatgggaa tttggttgcg taaagctgtt ttatttgcag ctgtgttagg ggctttgggg
    20041 gctgtttcaa aaactgttga agcatctgcc agcgaattta ttcgcggagc agatatttcg
    20101 atcctgtcag atatggaaaa atctggtgca aaatattatg aagacgatat ttcaaaagat
    20161 gccttagaga ttttaaaaaa taatggtgtc aactatgttc gactgcgttt gtggcaggat
    20221 ccttataata gtaatggaga aagttatgga gcagggacaa atgatctgga aacgacgatt
    20281 gaccttgcaa aacgagcaaa aaatctggga cttaaggtgc tgctggattt tcactacagt
    20341 gatttttggg ttgatcctgg gaaacagaat cttcctaaag catggcaagg tctgaccttt
    20401 gaagaaatga atacggcatt gtacgactat acaaagaacg ttctgtcgga aatgaagcag
    20461 ctggacgttt atcctgatat ggttcagatc ggcaatgaac tgaatagcgg aatgctctgg
    20521 ccttatggca agtcttgggg agaaggcggg ggagaatttg atcgattggc tgcttttttg
    20581 aagtctggta tccaagctgt tcgagacact caacctaaaa caactccagt aatgctccac
    20641 ttagctgatg gtggcgatac aggagcattt acttggtggt ttgatgaaat cacgagtcga
    20701 ggtgtgtcat ttgatttaat tggagtgtcg tattatccgt attggcacgg ttcaatgaat
    20761 gaacttcaaa ccaatatgaa tgcgatcagc caacggtatg gtaaagaagt gatcgtagtt
    20821 gaaacagctt atgggcatac aacagcgaat gccgatacta tgccaaatgc ttttggtgaa
    20881 gccgaagcag ctgcgggggg atatgaacca acaccgacag gacaagcaga gtatttgctg
    20941 gatcttgccg atcggattca ggcagtaccg aataatcgcg gggcgggctt cttctattgg
    21001 gaacctcttt ggtacaacgg aaatgtgagt tgggcaacac aagcaggtat gaattatctc
    21061 agtgttcaat ccactatggg aaacgaatgg gacaaccaag cgatgtttga ttttgctgga
    21121 aacgccttgc caagcttgcg tgcgtttaaa caagcagggg cgcaaataaa tctagttaaa
    21181 aatgcaagtt tcgaaagcga tggaccaacg accagtcctt ccaattggca aacctggttt
    21241 caacaaggaa ccgctaaggg tacgatcaaa acggaagcgg gcactttttt tggggactac
    21301 aaactaactt tttggcagga tcaagcatac gaggcatcag cttatcaaaa tgttagtggc
    21361 ataagcaaag gaacttacac attgagtgcc tatgtaatgt ctgggggaga gtttgatact
    21421 aatcagttat atatcaaaaa ttatggtgga gcggaactaa atactgcggt tgttaaaaca
    21481 agtgaatgga caaaaattac aatcaaagac attccaatta caacaggtgt ttgtgaaatt
    21541 ggggtttata gcaaggcttc aggaaatgct tggacgaacg ttgattttgt ttcattggtg
    21601 aaacaataga ctgcggatcg tttcgattca agatcggagg ttcccttcag ccacatcgtt
    21661 agcgtagaag gcaggaatcg aacctgcacc tcgcctttgc caaaaataac cagaaacgat
    21721 ttccagtcat ttttaccaaa acgagtaaag caccagactt catctacact ttgtattatg
    21781 ctaaagagag ttcaacgatt tcgtaagaag caatgaaaaa attgcaaaaa gttgtgcaga
    21841 taacataaag tttgtttaag aaagggtaac cttagaattc cgtcgtgaat atgatttgag
    21901 cacttagatg gatagaaaaa agttctcgga aaacagttcg tttttcgaga acttcttttt
    21961 atgataagaa tgaaacaaat taacttatat tatagtctct tttggtaggg aaccatctta
    22021 tttttaatga aaatcaagca ttttagctat tgaagaatgt tgatttatag ggattccccc
    22081 tccatattat gttggctctt tattcccact ccactgttgc tggtggttta gaagtgatgt
    22141 catacacgat acggttgacg tgggctactt cgtttacgat acgtacagag attttttgca
    22201 agacttccca tgggatacgg gcaaagtcag cggtcattcc gtcgattgaa gttacagcac
    22261 ggataccgac tgtgtagtcg taagtacgtc cgtcacccat aacaccgaca gagcggatcc
    22321 ctggaagaac agtgaaatat tgccagatat cacggtcaag tccagcagct gcgatttctt
    22381 cacgcaagat agcatcagat tcgcgtacga tttctagctt gtcttcagtg atttcgccaa
    22441 gaacacgaat accaagacca ggaccaggga atggctgacg ccaaacgatt gaatcaggca
    22501 tgcctaactg agtccctaat tcacggactt cgtctttgaa taatgtgttt aatggttcga
    22561 tcaattcaaa ttgcatatct tctggcagtc cacctacatt atggtgagat ttgatcgtct
    22621 gtgctgtttc tgtaccagat tcgataacgt cagtatacaa cgttccttgt gctaggaaag
    22681 agacgccttc ttcaccagca agttttgttg cttcgtcatc aaaaacatat acgaattcat
    22741 tcccaatgat tttacgtttt tgttctgggt cagatacacc tttcaacttg tctaagaagc
    22801 gatctcttgc attgactttg atgatgttca agccgaattt tccgcctaga ctttccatta
    22861 cttgttccgc ttcgcctttg cgtagcagac cgtggtcaac aaagatagat gtcaattggt
    22921 caccgatcgc tttttgtaaa agaaccccaa cgacactaga atcaacgcca cctgaaagac
    22981 caagcaagac ttttttgtca ccaacttgtt cacggatttt ttctacttgc atatcgataa
    23041 agttatccat tgtccagtta ccttcacagt gacaaacatc aaaggcaaag tggcgcagca
    23101 attcgattcc gtattcggaa tgacgtactt ctgcatggaa ttggatacca taaaaattac
    23161 gtgttgtgtc ttggatagaa gcaatcggac aatctttgct tgttccgact gtttcaaagc
    23221 cttcaggaac tttagttacc aagtcaccat ggctcatcca tactgtttgt tgttttggtg
    23281 tttctttaaa caagacagct tgatcgcttg ttacttctaa caaggctttc ccatattcgc
    23341 ggtttttagc aggctctacg gaaccgccaa gtttgtacgt gatcaattgc ataccatagc
    23401 aaatccctaa tacaggaata cctaaattga agatctcagg atcgatccca aatgcattct
    23461 catcatatac actgtttggt ccgccagaaa gaatgattcc ctttggattc atcgctttta
    23521 cttcttctgc agtaatgcgg tggctcaata attcggaaaa gactccaaga tcacgaatac
    23581 gtcttgtgat caattggtta tactgactac cgtagtctaa tacgataatc ttttcaacgt
    23641 tcgtcatatc ggcaacgttt gtcaaattta ttacccctat ccctttaaat tttatctcaa
    23701 aatagtcaaa ctattttaaa atgctaatat tttcgcatga aaatcgaatc gatgatatga
    23761 ttttcagttt tatggagaat tatatcggct cttcctcgtg taggcaagat atattcctgt
    23821 aaatttttca aattcacatt tttccataca tcttttgcca ttttaaaggc ttcttcacga
    23881 tctccgatag caaaacgata ataataattc tctggatttt ggaaagccgt atccagtaac
    23941 gcaccaaaac gatccaaata ccatttttcg atcagcacgg gatcggcatc gacatagaca
    24001 gaaaaatcaa aaaagtcgct gacgtagatt tgctgattcg caggtaattg aagcgtattg
    24061 atcccctcaa cgatcaagat atcaggctgc tggatcaatt cgtacttgtc tggaatgata
    24121 tcatacacat catgtgagta aacaggtact tttatctctt cctgaccaga ttttacacgg
    24181 ttcaagaaat cgatcagcat ctccatatca taactttcag gaaatccttt acggtccatg
    24241 attccacgct cttttaatat acgatttgga taaagaaatc cgtcagtcgt gatcagctga
    24301 acgtttcttc gtttgaaggt acgagacaaa atcgtctgca gcagtctggc tgttgtactt
    24361 tttccaacgg ctacacttcc ggcgatcccg ataataaaag gcggtacttc tacgtattta
    24421 tgaagaaata aacctttact caagaacaaa gattcaaatt ctttcatata aagataaatc
    24481 agatgagcaa gaggtacata gatatctcga acatcctgca tggaaatgcg gtcattcaaa
    24541 cttttgatat tatctagttc atcttgtgtc aaaggtgctt gcccattacg ataaaattct
    24601 cgccattctt ctcttgccac acggtagtag ttcattggat cattcatatt agcctcctgc
    24661 gttctcccat caatggaact attttaacac aaaataaacg caaaccccac cacttaagag
    24721 agattgccga tctttttgta taatctttat aatagaaaga aacggagtct tattcttgac
    24781 ttgcgcacgg atacataaaa ggatagactg ttgtcatgaa agaaatgaga aggatggaag
    24841 acatgacaaa tcattactat tctgaacgcc cagatacggc gcacgatttt gaacaatggg
    24901 cttttgagtt aaaaggcaga acctttcaat ttgtaacaga ttctggtgta ttttcacgtg
    24961 aaacagtgga ttatggttca cgtgtcctga ttgatgcttt cgattgggaa gagttacctg
    25021 atgaaggaaa gatcttagat gtgggatgcg ggtatggacc gattgggtta gctttggcat
    25081 ttgcgacaca gcggtttgtt gaaatggtcg acattaatga acgagcggta agtctagcgc
    25141 aaggaaacgc aaagcgtaac caaatcgaac atgttgatat ccatcaatcg aatatctatg
    25201 aagcagttca tgaagaaacc tatgcagcta tcgtaagcaa tccgccgatc cgtgctggaa
    25261 aaaaagttgt acatgaaatt ttgacaggcg catatcctcg gttgaagaag ggcggtacac
    25321 tgacaattgt gatccagaag aaacaaggag cgccgagtgc gcaaaagaaa atggaagaaa
    25381 catttggtaa tgcagaaatc gtcacaaaag ataaaggata ttatatcatc aaaagtgtga
    25441 aagaataact agctgaaaaa tagtggagcg acgaaagagt ggaactgggc gtgcatgtac
    25501 gggtacgtat cagttctttt tttgttgaga agtttttaaa aacaaagaac tattttttct
    25561 tcaaaaagaa atagtaggaa cagagtcgtt gttttttacg ataaaataaa taagatacag
    25621 aacttgtata gaagggagcc aataggatga agctgaccat cagagatatc gcagaaatgg
    25681 caggcgtatc agtaacaact gtctcacaga ttttgaataa caaaggaagc agatttagtg
    25741 ataagacaag aaaaaaagtg ttgtcgatcg tgaatgaaca tcattataag cccgattatt
    25801 tcgcttcaaa tgtgatcaat cgacattcaa agaccatcgg aatgatcgtc cctgatgtca
    25861 ctgatttctt cttctccaaa ctgatcgaag gtgtagagag ctatttgaat cctttgggct
    25921 atgtgatcat gttatgcaat tctcgtcata gccaagaaaa tgagatcaag tatttacaag
    25981 agctttccca ccgctcagtg gacggaatct tgctggccac accaaatatt ttacctgaga
    26041 aatatgcatt agacagcggt ttttatcaaa aaatgccaat cattttaatc gatcgcggat
    26101 tgaatcgtcg ggataacgga cggcttatcg taaaggaata tgagggcgcc tatcaagctg
    26161 tttcgctgtt tattgaaaat ggccatacga agatcggcat gctgaaggaa accactggat
    26221 actatcaatt agaagaacgt ttcaacggat atcgtcatgc gctgaaagat catggcctgc
    26281 cttttaatgg gaaatttgtt gaacatggag agttgactgt ccaaggtgga tatactgcat
    26341 caaaaaaatt actcaaacat aaagatatca cggctatttt ttgcgggaat gatgccatgg
    26401 cgatcggatg ctatcaggcg atcgatgaat tgggcaaaaa aatcccagaa gatatctcag
    26461 tcataggatt cgatggatta aagctgtcag aatacatgat tccgcaattg acgacagtgc
    26521 agcagccaag ttttgatatt ggattttatg ctgcacgttt cctgatcgat acgatcgaat
    26581 ttcctcaaag aaaagttccg aacaaagtgt tcgaaacaaa attaattatt cgtgagagcg
    26641 taaaagtatt gacaaaggct agttagtgct ttttttattt ttagtaaacc agtttactaa
    26701 agtggtttac ctttcctaaa aataatgtat aataccgaat gaagacaagg aggatcaggc
    26761 aatgcgaatg gtggatctga ttgaaaaaaa gagggatgga aacgagctgt cgaaagagga
    26821 aatcgagtac atcgtcacga actatacgaa tggaaagatt ccagattatc aagtcagtgc
    26881 attattgatg gcaatttttt atcaagacat gacaaatgaa gaaatcacga acttaacatt
    26941 ggcgattgct aattctggtg atgtcatcga tttgagttct cttgaaggaa taaaggtaga
    27001 taagcattcg acaggtggcg ttggtgacac gaccacattg attttagccc ccctagtagc
    27061 tagtgtcgga gtgacagtgg ctaaaatgtc tggacgcggt ctaggttaca caggtggtac
    27121 actagacaag ctagaagcaa ttcccggatt tcagatcgag ctttcggatg aagaatttgt
    27181 acgcattgtt aatgaaagta aagtagcggt aattggtcaa tcaggaaact tggcaccggc
    27241 ggacaaaaaa ttgtatgcct tgcgtgacgt cacagcgacc gttgattctc ttccgctgat
    27301 tgccagttcg attatgagta aaaaaatcgc ggcaggagca gatgcaatcg ttttggatgt
    27361 gaccactgga gacggtgctt tcatgaagaa catcgaagat gcaagacgtc tggcaaagac
    27421 catgacgagc attgggaaac tggctaaccg agaaacagtg gcggttatct cagatatgtc
    27481 agaacctctt ggcgaagcta tcggaaatag tctagaagtt gtcgaggcaa tcgaaacatt
    27541 acaaggaaat ggtccagaag atctagtaga aatgtgctac gccttaggaa gccaaatggt
    27601 tgttcttgct ggcaaagcta agacaaccga tgaagcaaga acgttgcttc aagaagctct
    27661 ggaatcaggt aaagcgttag caaaattcaa agaaatgatc caaaatcaag ggggagaccc
    27721 agcgatcgtg gaacatccag aacgaatttt gactgcacgc tacacaatgg agcttcctgc
    27781 taaacaaagc ggagttgtgt caaaaatcgt ggcaaatgaa ttaggaattg ctgcaatgat
    27841 gctaggtgct gggcgtaaaa ccaaagaaga agatattgat cacgctgttg gattgaaact
    27901 gcataaaaaa attggtgaca ctgtgacaaa aggtgagtca ctattgacga tctatagtaa
    27961 cgacgaagaa atcacttctg tcattgaatt attatataaa aatattgaaa ttggtgaatc
    28021 ggcaatgaag ccaacgttga ttcatgacat catcacagaa taaaggaaaa aagcggactt
    28081 taccgtttta aagaaaaggg gaaaagaaat ggaactaaac cgaatgatcg accatactat
    28141 tttgaaagca gacgcatcta aagaagctgt gatgcaaatt atcgaagaag caaaaaaata
    28201 ccatttttat tctgtctgca tcaatccagc atgggttgcg ctagcgaaag aacaattaca
    28261 aggtgagcca gtagccgtat gtacagtaat cgggtttcct ctaggagcaa acacacccga
    28321 gacaaaagca tttgaaacaa cagatgccat caataacggt gcagatgaag tcgatatggt
    28381 catcaatatc ggtgctttga aatcaaagga tgatcaacaa gtccaaaaag atatcgaagc
    28441 agttgttgaa gcagcaaaag atcgtgcgct tgtcaaagtt attattgaaa catcgttatt
    28501 agatagagaa gaaatcatcc gagcttgcga aatagcaaaa gctgcaggcg ctgattttgt
    28561 caaaacatca actggtttct caacaggcgg agcaaaggta gaggatgtcc gtttgatgcg
    28621 tgaaactgta ggaccagaaa tgggtgtcaa agcttccggc ggtatccata acgaagaaga
    28681 agcaatggca atgatcgaag ctggtgctac aagaatcgga acaagcgcag gagtagcaat
    28741 cgtatctggt tcaactggtg aaggctatta attttttcaa aggagaagct catggcagaa
    28801 ctcaaacaag aatggatcaa cacagctatt gaagcgttag ataaagccta tgttccttat
    28861 tcccattttc cggtaggcgc ttgtctcgta acggaatcag gcaagattta tcaaggcatc
    28921 aacattgaga atgcatcatt tggattaacg aattgtgccg agcgcacagc ttttttcaaa
    28981 gcagtatctg aaggagaaaa aacatttacg catctagtcg tagcggggca cacccccgat
    29041 cctatctctc cttgtggtgc atgtcgacaa gtaatggcag aattctgttc ccctgatatg
    29101 ccggttacgc tagtaggaga caatggtgtg acgaaggcaa cgaccgttcg tgcactgctg
    29161 ccttatgcat ttactgaaaa agatctataa ctcatgttca ttcagtcagc tgactgttga
    29221 aaaataaaac aattatttta ggaggcttta cagaaatgaa aaaagcaaaa ttatttggtt
    29281 taggtgctgt cgcactagca gcagggttat ttttaggtgc atgcggcaac aacggctcta
    29341 ctgattcatc cggtggcaaa agctcatcag acacaacaac tgcagcattg atcacagaca
    29401 caggtggtgt agacgaccgt tcattcaacc agtcagcttg ggaaggacta gaaaaatggg
    29461 ggaaagatca aggactttca cgaggaaatg atggcttcca atatttccaa tcttcaaatg
    29521 aatcagatta catcccaaat attgaccaag cattgaatgc tggattcaaa acgatttttg
    29581 gtattggtta taaactaaaa ccagcgatcc aagaacaagc aacaaacaat acaggtacga
    29641 actttgttat tatcgatgat gtcatcgatg gattagataa cgttgtatct gcaactttca
    29701 aagacaacga agcttcttat cttgcaggtg ttgcagcagc ttatacgact gaaacaaacg
    29761 tagtcggctt tatcggcggt gtaaaaggtg aagtaatcga tcgttttgat gctggattca
    29821 aagccggtgt tgatgcaggt gcgaaagaat taggaaaaga aatcaaagta ttgaatcaat
    29881 atgctggtga cttctctgct ccagataaag gacgttcaat tgctcaaggt atgtatgcac
    29941 aaaacgcaga tatcatcttc catgcttcag gcggtacagg taacggtgta ttccaagaag
    30001 caaaatcatt gaacgaatca ggcgacaaaa aagtttgggt tatcggtgtt gaccgcgacc
    30061 aatcagacga aggcgaatac acattaaacg gcgaaaagaa aaacttcaca ttgacatcta
    30121 cactgaaagc agttggaaca gtagtagaag atttggcaca aaaatcagcg gacggtaaat
    30181 tccctggcgg cgaacacact gtttatggat tgaaagaaga cggtgttggt ctaacagaag
    30241 gacaactttc tgacgaagcg aaaaaagcag ttgatgaagc aaaagaaaaa atcatttcag
    30301 gtgacgtaaa agttccagaa actcctgaag aaaactaaaa ccatttctat agccttgtta
    30361 gacacatgtt tgacaaggct atggtttgat tagaacaaga attgttcatt tatccaagct
    30421 gccttgtgac agtttggata agggaacaac tccctgaagt aatgtttgtt tcaaaagaag
    30481 aacgctcact aagcgtgaat cttagtcaat cgttgcccta gatagaaatc gttaggatgt
    30541 gaaaaaaagg tggttcaaga aaatattgtc atagaaatgc agaatattac caaagaattt
    30601 ggaacattca aggcaaatga caacatcaat ttacaagtaa aggcaggaga aattcatgcg
    30661 ttgcttggag aaaacggtgc tggcaaatct acattgatga acgtgctttc cggattatta
    30721 gagccgacat cagggaaaat tttgatgcgt gggaaagaag taaagatcac aagtccgacc
    30781 aaagccaacc aattagggat tgggatggtc catcagcact ttatgcttgt tgatgccttt
    30841 actgtaacag aaaacatcgt gttgggaagc gagcctagtc gcgcagggat gcttgaccat
    30901 aaaaaagcac gaaaagagat ccaaaaagtt tctgaacagt atggattgtc agtcaaccca
    30961 gatgcttacg ttcgtgatat ttcagttgga atggaacaac gggtagaaat tttaaaaaca
    31021 ctttaccgag gagcagatgt actgattttt gatgagccga cagctgtatt gacccctcaa
    31081 gaaattgatg aattaatcgt gatcatgaag gaattagtca aagaaggcaa gtcgatcatt
    31141 ttgattacgc ataagttaga tgaaatcaaa gcagtagctg accgctgtac agttatccgc
    31201 cgtggaaaag gaatcggtac agtcaacgtt aaagacgtaa cctcacaaca attagccgat
    31261 atgatggttg gaagaacggt ttcattcaaa acgatgaaaa aagaagcgaa gcctcaagaa
    31321 gtcgttttgt ctattgaaaa tctagtggtg aaagaaaatc gtggattaga agccgtgaaa
    31381 aacttgaact tagaggttcg tgctggcgaa gtacttggta tcgctggaat cgatggaaac
    31441 gggcagtcgg agttgatcca agctttgact ggtttgcgaa aggcagaaag cggacatatc
    31501 aagctaaaag gggaagacat cactaataaa aaaccccgaa aaatcactga acatggtgta
    31561 ggacacgtgc cagaagaccg tcataaatac gggttagtcc tagatatgac attatctgaa
    31621 aatatcgcac tacaaaccta tcatcaaaaa ccttacagta aaaacggcat gctgaattat
    31681 tcagtaatga atgaacatgc cagagaattg atcgaagaat atgatgttcg aacaacgaat
    31741 gaacttgttc ccgcaaaagc tttatcaggc ggaaatcagc aaaaagcaat tatcgctcgt
    31801 gaagtcgacc gagatcctga tctgttgatt gttgcaaatc caactcgtgg actggatgta
    31861 ggtgcgatcg aatttattca taaacgtctg atcgaacaaa gggacaaata caaagcagtg
    31921 ttactgatca gtttcgaatt agaagaaatt ttaaatgttt cggatcgtat tgctgttatc
    31981 catgaaggag aaattgtcgg tatcgttgat ccgaaagaaa catctgaaaa tgaattaggt
    32041 ctattgatgg cgggctatac cttagaagaa gcacgaaaag agttagaaaa gggggctggc
    32101 gcacatgaat gatcgcagcg aaaaattccg taatttatta gtgcctgtac tttcagttgt
    32161 tttaggattg atcttaggcg cgatattgat ggctgctttt ggttttcagc ccatccaagg
    32221 ttattcttct atgctagatg cagcccttgg ttcgcaaaga gggataggtg aaacgttaag
    32281 gcaagcaacg ccgttgattt ttacagcatt aggtttttct gtagctaact cagctgggtt
    32341 tttcaatatt gggctttctg gacaagcact ttgcgggtgg atcgtcagtg tctgggtggc
    32401 acttgcgttt ccagatctgc caaaagttgt tttgcttccg ttatgcgtga tcttaggtgc
    32461 cttagctggt gcgatggcag cggctgttcc aggtttactt cgagcatttt ttggaacaag
    32521 tgaagtgatc gtaacaatca tgatgaacta tatcttatta tacgtaagca catttgcttt
    32581 acatgaagtg atgcctgaaa gctatcgctc aagtttggac tcttccaata tgatcagtca
    32641 aaatgcctca ctgcggttac catggttaac acaagctttt ggcggctctc gcgtaaactc
    32701 aggattattt ttagcaatca tcgcgcttat tttcgtttgg ctgctgatga agaaaacgac
    32761 tttaggattt gaaatccgtt ctgttggatt gaatcctttt gcttctgagt atgcaggaat
    32821 gagtagtaaa cgtacgatcg ttttgtcgat ggtcatttct ggcgctttgg cagggcttgg
    32881 cggtgtggtt gaaggattag gaacgtatca aaacttcttt gttcaaacga cttcgctatc
    32941 tattggattt gacggaatgg ctgtttcctt gcttggttct ggatcagcaa tcggtattct
    33001 tttatcagcg atcttgttca gtattttgaa gatcggtgga cttggcatgc agacaggagc
    33061 aggtgttccg tttgagatcg tcaatgtatc gattgctttg attatcttct ttgtcgggat
    33121 caacttcctg attcgtttcg tcatggctaa agtcttccaa gggaaaaaac aagaagagat
    33181 cgttgcgaca atagaatcga aaccaacgaa tcaaaaccat gaagggggcg aactataatg
    33241 tcgactatcg aattaattgc cttgatcctt acttctacac tggtttattc aacaccgcta
    33301 attctaacgt cactaggcgg aactttttct gaacgaagcg ggatcgtaaa cgtagggcta
    33361 gagggaatca tggtcatggg tgcttttagt tccatcgttt tcaacttgac gatgagtcca
    33421 tcacttggtt ctatgacacc atggatcgct attttagtgg gtggcgtcgt aggtatccta
    33481 ttttctctga ttcacgcagt agcaacagtc agtttgcgtg ctgaccatat tatcagcggg
    33541 acagtaatta atctgatggc acctgcttta ggtgttttct tgatcaaagc atggtatggt
    33601 aaaggtcaaa ctgataacat cacgcagaat ctggggtatt tttctttccc aggattagca
    33661 gatattccgg tcattggacc aattttcttt aaaaatacat tcttacctgc ttattgtgct
    33721 attttgattg ctgtcctagc ttgggtgatc atcttcaaga cgaaattcgg cttgcgcctc
    33781 cgttcagttg gtgaaaatcc tcaagctgcc gacacattag gtatcaatgt atatgctatg
    33841 cgttattcag gcgtactgat ttctggcttg ttaggcggta tgggcggtgc tgtttttgct
    33901 cagtcgattt ccggtaactt ttcagctggt acgatcgttg gacaagggtt catctccatg
    33961 gctgctatga tctttggtaa gtggaatcct ttaggggcaa tgggtgcctc attgttcttt
    34021 ggttttgctc aaagcttgag tatcattggc gcacaattac cagttatttc ttcgattccg
    34081 ccagtattgc tgcaaattgc tccatatttg ctgacaatca ttgtgctggt tgttttctta
    34141 gggaaagctt ctggtccaaa agcaaacggg aagaactata tcaaatcaaa ataatctttt
    34201 agcgaataaa aagggtgggt tacgggaagt gtttttcgtc tcgccctttt tgttttaaag
    34261 gcaataaaaa taaaaagaaa gaaggaataa tcatgtttaa acgcgtacat ctgatcgtca
    34321 tggattcagt aggaattgga gaagcaccag atgccgataa gttcggtgat gttggttctg
    34381 atacattagg acacattgcg aaagaagcag gattgaacgt tccacattta gagcagcttg
    34441 gtttaggaac gatccgtcct cttgaaggtg tggaatcagt gaaagatcat caaggctatg
    34501 cgacgaaatt agaagaagtt tctgtaggga aagatacgat gacaggccac tgggaaatca
    34561 tgggattgaa tatcaaaact ccatttcgtg tgtttcctaa tggattccct gatgatctga
    34621 tcaaacaaat cgaagaattt tctggccgta aagtcgtatg taacaaacct tatagcggaa
    34681 cagctgttat tgacgattac ggtgaacacc aaatgaaaac aggcgattta attgtatata
    34741 cttctgccga tcctgtcctt cagatcgcgg cacatgaaga aatcattcct ttagaagaat
    34801 tatatcggat ttgccaattc gttcgtgata taacaaaaga tgatccgtat atgattggcc
    34861 gaatcattgc acgtccgtac gtgggtgaac caggagactt cacacgaaca agcaatcgcc
    34921 atgattatgc gttgaatcca ttcggacaca cagtccttga ttctttgaaa gaagcaggaa
    34981 aggacgtgat tgctgttgga aagatcaacg atattttcaa cggacaagga atcactgaat
    35041 ctgtccgcac gaaaagcaat atggatggcg ttgaccagct gctgaaagtt atgaaaaacg
    35101 atttttcagg aatcagcttt accaatttag tagattttga tgcattatac ggtcatcgtc
    35161 gggatgtagt cggctatgcg catgcgattg aagaatttga cttacgaatt ccagaattgc
    35221 ttgaagcgat ggaagaagac gacttgctaa tgattacagc cgatcacgga aacgatccga
    35281 cgtttactgg taccgatcat acgcgagaat atgtaccgtt attggtttac agtaaaaaaa
    35341 tgaaagaaca aggggcattg cctcaaggat attattcaga tatttcagca acgattgctg
    35401 agaactttag tgtttcttcg actgaaaatg gcgaaagctt cttgaaatta ttaaaataat
    35461 ctttttaaat aggagaaagc aaatgaccaa gttaagcgag atgttacaag aaacgaccca
    35521 gtttatcctt gataaaggag taaaagaaat tgattttggt ttgattctag gttcaggatt
    35581 aggtgaatta gcagatgaaa tcgaagatgc tgtaatgatt tcttatgatg agatcccgtt
    35641 ctttcctgtt tcgacagtag ttgggcatgc aggaaagcta gtttatgggt ctctggcagg
    35701 caagaaagtg ttagccatgc aagggagatt ccactactat gaaggtcatt ccatgcaaac
    35761 agtgacctat ccagtacgtg tgatggccgg actaggggcc cattcagtca ttgtgactaa
    35821 tgcatgtggt ggtgtcaacg aatcatttgt accaggagat ttgatgctga ttaccgatca
    35881 tatcaatttt actggtgaaa atcctttgat cggtccgaat gaagatgcaa tgggccctag
    35941 atttccagat atgagtcaag cttatacgcc tgactatcaa gcaacagcaa aagcagcagc
    36001 agaaaaacta ggtttggatc ttaaagaagg cgtatatatg ggctattctg gaccaactta
    36061 tgaaacgcct gcggagatcc gaatgtctcg gacaatagga gccgatgcag tagggatgtc
    36121 gactgttcca gaagtcatcg tagcagctca cagcggatta aaagtgttag gaatctcttg
    36181 tattaccaac ttagcagcag gtatgcaagc gaatctgagc catgaagaag ttgtagaaac
    36241 aactcagaga gtcaaacaat cttttaaagc attggttaaa gaaacattga cattattgta
    36301 ataggaggaa caataaaatg agtgtgcata ttgaagcgaa agaaggcgag atcgccgata
    36361 agattttact tccgggagat cctttgcgag ctaaatatat tgcggagact tttttggaag
    36421 atccagtttg ttacaatcag gtacgcggta tgttaggctt taccggcaaa tataaaggag
    36481 aacgtatttc tgttcaagga acaggaatgg gaatgccatc agccaccatc tatgcccatg
    36541 aattgatcca gtcgtatggt gtaaagaaat tgattcgagt aggtacatgc ggtgcattgt
    36601 caaaagacgt ccatgttcgt gatttagtac tagcacaagg tgcagcgacc agttcttcga
    36661 tgatcgaaaa aaatttccaa gcctttcatt ttcctccaat cagtgatttc aatctattac
    36721 tgaaagcata tgagatagct aaagaaaagg gctatacggt tcatgtagga aatgttcttt
    36781 cggaagattc tttctacaaa gatgatttga cagagacgtt ccaattagct gaacttggcg
    36841 ttttaggagt ggaaatggaa gcagcggctc tttattactt aggcgcgaaa taccatgtgc
    36901 agacattaag tttgatgacc gttagcgacc atttgatcac cggtgaagaa acaacagctg
    36961 cagaacgtca atctacgttc aatgaaatga tcgaagtagg attggaaaca gcgatagcag
    37021 aataagaagg aaatgaaaaa gctgccctgc attaagtaat aagaacatcc aagcaaaaat
    37081 agctcctcat gtttttgact tggctggact tattattgca aatgtaagct tttgaacacc
    37141 gtttaccaag aggttgtgaa
//
LOCUS       DADQCX010000018        35386 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.018, whole genome shotgun sequence.
ACCESSION   DADQCX010000018 DADQCX010000000
VERSION     DADQCX010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.018"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(3..1529)
                     /locus_tag="J8R83_000841"
     CDS             complement(3..1529)
                     /locus_tag="J8R83_000841"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAZ9573989.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(1544..2191)
                     /locus_tag="J8R83_000842"
     CDS             complement(1544..2191)
                     /locus_tag="J8R83_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAZ9573990.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(2375..2704)
                     /locus_tag="J8R83_000843"
     CDS             complement(2375..2704)
                     /locus_tag="J8R83_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAZ9573991.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            2881..3609
                     /gene="sfsA"
                     /locus_tag="J8R83_000844"
     CDS             2881..3609
                     /gene="sfsA"
                     /locus_tag="J8R83_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAZ9573992.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            3625..4638
                     /locus_tag="J8R83_000845"
     CDS             3625..4638
                     /locus_tag="J8R83_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9573993.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            4638..5915
                     /locus_tag="J8R83_000846"
     CDS             4638..5915
                     /locus_tag="J8R83_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAZ9573994.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            5978..8680
                     /locus_tag="J8R83_000847"
     CDS             5978..8680
                     /locus_tag="J8R83_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9573995.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            8832..9149
                     /locus_tag="J8R83_000848"
     CDS             8832..9149
                     /locus_tag="J8R83_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9573996.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            9179..9499
                     /locus_tag="J8R83_000849"
     CDS             9179..9499
                     /locus_tag="J8R83_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9573997.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            9607..11067
                     /locus_tag="J8R83_000850"
     CDS             9607..11067
                     /locus_tag="J8R83_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9573998.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            11135..11356
                     /locus_tag="J8R83_000851"
     CDS             11135..11356
                     /locus_tag="J8R83_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9573999.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            11387..11569
                     /locus_tag="J8R83_000852"
     CDS             11387..11569
                     /locus_tag="J8R83_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAZ9574000.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            11569..11982
                     /locus_tag="J8R83_000853"
     CDS             11569..11982
                     /locus_tag="J8R83_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAZ9574001.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            12105..13286
                     /locus_tag="J8R83_000854"
     CDS             12105..13286
                     /locus_tag="J8R83_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574002.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            13675..13748
                     /locus_tag="J8R83_000855"
     tRNA            13675..13748
                     /locus_tag="J8R83_000855"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13709..13711,aa:Arg,seq:cct)
     gene            complement(13785..13985)
                     /locus_tag="J8R83_000856"
     CDS             complement(13785..13985)
                     /locus_tag="J8R83_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9574003.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(14290..15522)
                     /locus_tag="J8R83_000857"
     CDS             complement(14290..15522)
                     /locus_tag="J8R83_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAZ9574004.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            15776..16345
                     /locus_tag="J8R83_000858"
     CDS             15776..16345
                     /locus_tag="J8R83_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574005.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(16523..16963)
                     /locus_tag="J8R83_000859"
     CDS             complement(16523..16963)
                     /locus_tag="J8R83_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAZ9574006.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            17121..17885
                     /gene="map"
                     /locus_tag="J8R83_000860"
     CDS             17121..17885
                     /gene="map"
                     /locus_tag="J8R83_000860"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAZ9574007.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            17917..18840
                     /locus_tag="J8R83_000861"
     CDS             17917..18840
                     /locus_tag="J8R83_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAZ9574008.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            18916..20055
                     /locus_tag="J8R83_000862"
     CDS             18916..20055
                     /locus_tag="J8R83_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAZ9574009.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            20048..20848
                     /locus_tag="J8R83_000863"
     CDS             20048..20848
                     /locus_tag="J8R83_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9574010.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            20848..21675
                     /locus_tag="J8R83_000864"
     CDS             20848..21675
                     /locus_tag="J8R83_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9574011.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            21653..22387
                     /locus_tag="J8R83_000865"
     CDS             21653..22387
                     /locus_tag="J8R83_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9574012.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            22487..23353
                     /gene="rfbA"
                     /locus_tag="J8R83_000866"
     CDS             22487..23353
                     /gene="rfbA"
                     /locus_tag="J8R83_000866"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAZ9574013.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            23367..23939
                     /gene="rfbC"
                     /locus_tag="J8R83_000867"
     CDS             23367..23939
                     /gene="rfbC"
                     /locus_tag="J8R83_000867"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAZ9574014.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            23961..24989
                     /gene="rfbB"
                     /locus_tag="J8R83_000868"
     CDS             23961..24989
                     /gene="rfbB"
                     /locus_tag="J8R83_000868"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAZ9574015.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            25087..25938
                     /gene="rfbD"
                     /locus_tag="J8R83_000869"
     CDS             25087..25938
                     /gene="rfbD"
                     /locus_tag="J8R83_000869"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAZ9574016.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            25973..28006
                     /locus_tag="J8R83_000870"
     CDS             25973..28006
                     /locus_tag="J8R83_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574017.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            28050..29330
                     /locus_tag="J8R83_000871"
     CDS             28050..29330
                     /locus_tag="J8R83_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAZ9574018.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            29540..30346
                     /locus_tag="J8R83_000872"
     CDS             29540..30346
                     /locus_tag="J8R83_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574019.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            30358..31578
                     /locus_tag="J8R83_000873"
     CDS             30358..31578
                     /locus_tag="J8R83_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574020.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            31568..33154
                     /locus_tag="J8R83_000874"
     CDS             31568..33154
                     /locus_tag="J8R83_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9574021.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            33193..35331
                     /locus_tag="J8R83_000875"
     CDS             33193..35331
                     /locus_tag="J8R83_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9574022.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT        11212 a         6067 c         7356 g        10751 t
ORIGIN      
        1 tatcaatcgt ttaattttcc acgttcacga taccagttat ctggttgcca gatccattcg
       61 aatccgtctt tttcaagtag ttcgaaagct gctttaggtc ccattgatcc agctttgtag
      121 ttgggaaaat ccggttgtgt ttggtcccaa gcttttcgaa tgacatccac gatatgccaa
      181 gattgagcga cttcttccca atgagagaag ttcgttccat caccattcaa cgcatctaat
      241 agtaattttt cgtaagcttc tgggctattt tcaaccattt ctgcactatt tctaaattcc
      301 aatttgattg gttccgtttc aaatccttgc cctacttctt tcccattcaa ggataaagaa
      361 aatccttcag ttggctgaat atagatcgtt agaacattag gtggaagtgt cgtatcgtca
      421 catggttcat cgacagatgt tttgaataca ttaacaggaa cttgtttgaa tacgatgttg
      481 atccgagtcc ctttttcagt caaacgtttg cctgtacgta catagaaagg aacacctgac
      541 caacggaagt tatcgatagt gaatttgcct gcgacgaatg tttcagtctc tgattgagca
      601 tccactttgt cttcttcgcg atagcccttg aattgtacac catccaattc accttgagca
      661 tattgcccgc gaacgaagtt ttctaacact tcttcttcgt tataaatgcg gatagctttc
      721 aatgctttga tcttttctgt acggatttct ttttcggaaa atgctactgg cggttccatt
      781 gcaagtaatg ctacaacctg taaaatatga ttttgcacca tgtctttaag tgcgccacta
      841 tgatcgtagt agcccccgcg atcttctaca ccgaggtttt cgccaaaagt aatttggata
      901 ttgtcgatat agcgattgtt ccattgagcc tcaaaaatat tattggcaaa acggatagct
      961 gagatgtttt ggatcatttc ttttcctaaa taatgatcaa tcctgaaaat atcttgttct
     1021 gggaatactt ctctgatttg ctggttcaat tcaaaagcag actggtaatc agaaccgaac
     1081 ggtttttcta tgatcaaacg attgaagcca ttttttgtca taatattttg tgatttcaaa
     1141 tgagaaacga tcgttccaaa aaattgaggt gccatagcca aataatagac acggttaccg
     1201 tttaattgat agtgtccatc taatcggtca gacaattctt ttaatgtctg ataatgcgtt
     1261 gaatcattta catcatggga ttgatagtaa aaatggcttg caaaggtagt tgcttcttca
     1321 tctgaaggat tcaatgcacg gattgtttct ttgacaactt cacggtagtg ctcatcgctc
     1381 cagggacggc gagcggttcc gattacagca aaatgctcgc ctaaatttcc ttttctgtaa
     1441 aggcggaaca aagacgggta caatttacgc tgggctaggt cacctgtacc gccgaatatc
     1501 gtaaacaata catttttttc attagacatg tggatacact cctttatatt ttatcgacaa
     1561 aaatcgtgct ggccgcctta aagctgacgg ggattttctt tctatcattt tggatagtga
     1621 tcggtccttc ataagctgcg atgtcaacga tctcatattc ttcgttgata ttcaggtcaa
     1681 tagtgactaa gtaatccaac aattcttttt catcaagcac tcgtgcgata cgcacttttg
     1741 taccgacagg ataggactcc aatgtttgtc ggcgttcttc atggacaact tcctcttttt
     1801 taggaatcga tcctccatga ggacaatgtt caggatgatt caaatagttt tctaaatgat
     1861 ctgcaagatg ttccgaagtc acatgttcca atacttcagc atcatcatgg acttcattcc
     1921 agctatagtc taaatgttca actaaaaaaa cttcccataa gcgatgtttg cgaatcagac
     1981 tgctagcttt ttgcagtccg cttgcagtca attgtacacc ttgataaggg gaatgttcta
     2041 caagctcttc tttcacaagt ttagaaatca tttcactgac agatgcagct gagacatcta
     2101 gactagatac gatttgttta ttgttgactt tcgttgtatc tccacctagt tctaaaatga
     2161 ttttcaaata atcttctcga tttggtgtca tattcgatca tcctttcatg gtaaaaaacc
     2221 atcattagta agtgtaacaa aaaaaacgtt aattgactat ttttctaaat aaaaaacaaa
     2281 ggatttttag acgtttttac aacaaaaaac gaaagatgat agagaagact cattctttcg
     2341 tttataaagg atatatatat acattgggag ggatctattt ttcagataac aacttatatg
     2401 aagtgtctgc agattcgtca taaagagttt gttcgggata agaaaagata agataaaaac
     2461 catactgatc acgtacgact aaacgatatt catctatttc taccacagat gtgccaagag
     2521 actgaccgtt gatcaaaaac gtgtaatcag atgtaatctg taattgttgt ttttgctggc
     2581 tatcactaaa gaaccatgta ccttgatact ttgagagtcc ttctgacttt tccgcttgtt
     2641 ttttcttttt caagtaaata aaacttgaga gaacggtaat gagtgaacca agaaaataga
     2701 tcattttttt tatcaccaaa tcactccttt atgagaaaat aatcgcatag acatattctt
     2761 tcttctttat ttcattgtac cgaataaaag ctaaaatttc tctaagactt tcgactggtt
     2821 tttttactgt ttttctacaa attatgatag gatacatagt aggaagaaag gtgacataat
     2881 ttgaagtatc agcaagtgga aatagctttt tttattgacc gcccgaatcg gtttatagca
     2941 cattgtatga aaaaagacgg agaaataatt attgcgcatg tcaaaaatac aggtagagga
     3001 aaagaggtcc tgataccagg cgctgaagtg gctattgtat ttgctcctgg acctaaacgg
     3061 aaaaccgcct atgatctgat tgctgtaaaa aagaagggtg actggtttaa tatcgatagt
     3121 caattgccta atcggctggc aattgatggt attttagacg gcacgatcct tttaccagga
     3181 ttaactggtc catttacggt atacaagcgt gaagtaactt atcttcactc caaatttgat
     3241 atttatttag agacggtggt cggacaaaaa gcatttgttg aagtcaaagg tatgacactt
     3301 gaaaataaag cgattggtgc ttttcctgat gcgcccacac tcagaggatt gaaacatata
     3361 ggagaattaa cgtatgccgc acaagatggt tatgccgctt atgtcttgtt tattgctcag
     3421 ttcgaacatc ttcatctggc aacgatccat gaagaaatgc aaccagcact agctgatatg
     3481 gttcgacatg cgcagcaaag cggagttcaa atcctcgcct ataattgtca agtatcggca
     3541 gatgaggtaa ctgtcaagca ggccattcca tttgatgtag atatcccttt tgaagatcct
     3601 atacaataga aagaaggtaa aataatgatc aacttaggta ttatcggaac aaattggatt
     3661 actcatcaat ttgtccaagc agctttaagc acaaaaaaat atgaattgac agcggtatat
     3721 tctagacatt tggaaaaagc acaggaattt ggttctcatt atgaagggga tatcgaattc
     3781 gcaacagatt tgaagacttt tttcaatatt actcatatgg acaccattta tattgcttct
     3841 ccgaatagtc ttcactttag tcaagctaag caagcaattt tggcaggaaa aaatgtgata
     3901 gttgaaaagc cagctttttc gacgccaaaa gaaatggatg aaatcatcca tttggcaaat
     3961 gaacacaatg tgtatttttt tgaagcagca agaaatatcc atgaatcagg ttttaaaaag
     4021 attgccgatt acttaccatt aaaagacgag ataatcggtg caaatttcag ctatatgaaa
     4081 tattcttcgc gctatgacca agtattagat ggagaagaac cgaatatctt ctcgactcat
     4141 ttctcaggtg gtgcattgat ggatttaggt gtttaccttg tatatgcagc tgttgcttgg
     4201 tttggaatgc caaaagaagt ccattatttc ccaagaaaga tttctactgg tgtagatggt
     4261 cttggatggg ggatcttacg ttatgagaat tttgatgtat cgatccagcc aggtaaaatc
     4321 ggtgattctt atttaccgtc agagatttat tttgactcag gaacgctagt gatgaatgga
     4381 gtcaatgcaa ttgaacaagc acaatttcat gatcgcgcgc ataaagaaat cattgatttg
     4441 gcggtaacag ctgcagaaaa tccaatggca gatgaagcag aggattttgc caatgtcatg
     4501 gctcatccga aagatccagc ttggggattg ttgtatgaag agtggatcga gctagctaga
     4561 aatgtgaacc aagtgattta tgatttaaga aaaaatggcg gcatcaaatt cgatgcagat
     4621 aatgaggaag atttttaatg aacgaatttg tacaagtatt tcccgaaaat tggcagaaaa
     4681 aatatgagga taaagggttt atctcacctt ctcttattca acgagcagtt tttcagccac
     4741 taagtaataa acaaagtata gtagcggttt ctcctacagg ttcaggtaaa acactggctt
     4801 atctttggcc tctactacta aacgtggaac caggtgaagc aagtgcgttg gtcatttttg
     4861 cttcttctca agaactagct attcaagtag cagatgttgc acgtgaatgg ggaaaagaca
     4921 aagagttgaa agtccaatct ttggtgggcg gagccaacgt caaacgtcag attgagggtt
     4981 tgaaggaaaa accagaaatc ttgattggta caccaggaag aatattggaa ttgatgaaag
     5041 caaaaaaaat aaaagcacat caagtgaaaa caatggtatt tgatgaagca gaccagctat
     5101 ttgacgctgg gaacagccaa atcattgatc aaattcttca tcaagctcca acagagtatc
     5161 agctagcttt tttttcagcg acagcagatc gttcccttga aagcattgaa aaaatcactg
     5221 ggaaaacgtt tgagacaatt gacgtgacag cagaggacga ttctcgaaaa ggactgagac
     5281 attacttttt acgtgtaccg atacgaaaga aagatgacta cttgagacgt ctcacgcata
     5341 tagaagattt tcatggtctg attttcttta atcaactgac tgaattaggc gtaatggaag
     5401 aaaaattgct gtatagaggt gtaccggtag gaagtctggc ctctgatcag aacaagctac
     5461 tccgaaaagc agcgctagaa caattcaaaa agaaaatggt cagagcactt ttgaccacag
     5521 atgtggcggc tagaggttta gatattacag gtcttcctta tgtagtgaat gcagaagttc
     5581 cgttaagtga agaagcttat ttgcatcgtt cgggaagaac tggtcgaatg ggtaatgaag
     5641 gaatagtaat tacactcgta caagataata atctaagaga tttaaaacgg cttttacgtc
     5701 catcaaatat aacacttgaa gagatttttt tatacggagg taagctgcaa actgagcagc
     5761 caaccaaaga agatgcagct cctgcagtaa ataaaaagta tgcgaaaact ttttctggaa
     5821 aggagcagaa cccagaatat aacaaagaaa aaataagaaa aaaagttaaa aataaatcaa
     5881 aaaaagagag aaataaagga gcaaggcgca aataagcgcc tttttatgct atgattatga
     5941 aaacgggaac aaaattggtt gccagaggag gggttatgtg aaagaacgtc aagaagagat
     6001 cttgcagcta ttgacagaaa accaacaagg attgacagca agtgatgtag ctgagcgctt
     6061 aactatcgat cgaagcaatg caagccgata tttaagtgaa ctatacaagg cccatcatat
     6121 tgtaaaaacc gctggccgac cagtcgttta ctctttgcca acggaaaagt caaaatctga
     6181 tgaagtgcat gtcgactctt ctacgcaagt gacttttgaa acactcgttg gagaaaatga
     6241 ttctttaaaa gtcagcatac agcaggcaaa agctgcgatt ctttatccac cgcgggggtt
     6301 gcatacgatt atttttggag aaactggtac agggaagtcg atgtttgctg aatgtatgta
     6361 tcattttgca atcgattcag agatgctttc tgcagatgcg ccatttgttt ctttcaattg
     6421 tgcggattat gctcaaaatc cgcaactgct ctttggacac atctttggga tcaaaaaagg
     6481 ggcttacaca ggagcagctc aagatagtcc cggtctaata gccaaagcag acggcggtat
     6541 attgttttta gatgagatcc accgtttacc gccggaaggg caggaaatgc tgtttacttt
     6601 cattgataaa ggtatttacc gtccgcttgg agaaagtgca caagtacatg aagcatctgt
     6661 tcagatcatt ggggcgacga ctgaatcttc agaaagtttc ttatctacgt tcaatcgacg
     6721 gattcctatg gcaatcacct tgccgaatct tgcttcacgt tcactggatg agcgttatga
     6781 aatcatctct ctttttatca aacaagaagc gaatcgtttg aatcaacgta tcgatatcga
     6841 aaaagaagcg attcttgcct tcatgcttta tgatgcggaa ggaaatatcg gtcaagtgaa
     6901 acgagacttg aaactagtct gtgcaaaatc ttttttacat taccgtactc atcatgagaa
     6961 aaagctaatc attcgaaaag aagaactttc ccttcaagta caaaaaggat tactgaaaat
     7021 caaggaaata ccggaacgtc tcgaccgatt catggacagc aaaagtcagt atttgacatt
     7081 tgaaccagga tttgctgatg ttgtctggtc acaagatcca gaacgaaaca tgcaggtcta
     7141 taacgatatt gaggaaaaag tcacttctct ttccgaaacc ggtgtggaga acattgatct
     7201 agagaccctc atttcaaaag atgtggatgc ttatttccag acatatgtca aagaattgac
     7261 taaaagttcg attcccaaag atcttttgcc agatgaaatc tggcggttaa ccaatcaatt
     7321 gtatgatgtg gctgaaaaac ggttagaccg tatttataat gaaaaagctc gttttgcttt
     7381 tgctttgcat ctgcaaagta cattggatcg tgtgagagaa ggtcatatga tcgtccaccc
     7441 agatttgaat aacgtacgga aaaattttaa gagggaattc caggtagcaa tcgatctttc
     7501 aacgatcatt gaagaagaag aacaagttga gattcctttt gatgaaatcg gctttattag
     7561 tatgtttctt tctatcaatc taggagaaag tgagcctgtt aaagaaaaca aagtagatgt
     7621 tctcatattg atgcacggca gacagactgc ttcaagcatg ttggagatgg cacaagaact
     7681 attaggaaca aaagtaggga aagcttttaa tatgccactg gttatggaag ttcaaacaat
     7741 gtatgaagaa gtgttacaat atgtcaaaaa ctatcaagag catttgacga atggcctact
     7801 cttgttaaca gatatgggat cattaaacac cttcagtgat ttgatttatg aagagactgg
     7861 cattcggacg aaagctatca cgatgacaag taccatgatt gtgatagaag cgatacggat
     7921 ggcaagtgtt ggaagaagct tagaagatat ttatcaaaat atccagcttt cctttgaatc
     7981 gatcgtacgt gatcagttca aagcggaaaa gtctgaaact ttacagcgta aaaaagccgt
     8041 aatcgtgaca tgctttactg gtgaaggagt agctgccaaa ttatatcagc gtattatgcc
     8101 agtgattaat caaaataagg tagaactgat ccagatgcag tttttagaac gtgaatcatt
     8161 caaaaaacac atcgatgcct tattggaaga atatgagatc aaagcaattg cgggaacagt
     8221 tgatgttgat tatcaaaata tcccattttt ttcagcctat gacgtttttg atgatgaaaa
     8281 actaaatatt ttaaagcgta tagctgatga tgagatcccg acagctaaaa ttgtcgattc
     8341 acttgctgga tcattaagcg atgtcttttc tattgatgaa ctgatccgtt cattgcaaaa
     8401 gacagttcag cagatccaga ccgatttgtc gattatcgtg gaacctggag tagatactgg
     8461 aatcgttatc catttagcct tcatgttaga cggattgatc aaacaagaaa gccatcggca
     8521 atttgagaaa ctgtctattt tctcaaaaat ttatcgtttg gaaatggata tcgttcgggc
     8581 aaacttgatg gcactagaac gaaaatatca ggtaaaaatt ccagaagatg atatcgcatt
     8641 tcttacacaa atgtttcttg aaaataaaat aaaaaaatga acacactaat catactgttt
     8701 acacactaaa catctgtgtg cgcactataa aaaagagcta aaaagcatga aaacgctatt
     8761 tcagctcttt tttttattgg catgcttctt gcgttatata aaagtgtaaa aaaataaaag
     8821 gagtgttaaa aatggcaaaa aaaacaatca tgttagtttg ttcagcaggg atgagtacga
     8881 gtttattggt cacaaaaatg caaaaagcag cagaagaaaa agggatggaa gccgatattt
     8941 ttgcggtctc tgcctcagat gcagataata atttagaatc taagaatgtc gatgtattat
     9001 tattaggtcc tcaagtacgt ttcatgaaag ctcaatttga acaaaaactt gcgcctaaag
     9061 gtattccatt agatgtcatc aatatgcaag actatggcat gatgaacgga gaaaaagttc
     9121 ttgcacaagc agaaaatcta atgaaataaa tcaagtatgc agttgggggt ataacaacgt
     9181 ggaagatcaa caaaatctag aagccatcat ggggttaatc atgtttggcg gtaatgcaaa
     9241 gagcgatgca atggaagcga ttgcggctgc taaaatcggt gattttgagt tagcggatag
     9301 gaaaatcgct gatgcagaag aatcacttat acaagcgcat catgcacaaa cagacatgtt
     9361 gacacaagaa gcacaaggaa atcatatgca agtgacatta ttgactgttc acagtcaaga
     9421 tcacttaatg acatctattg cgtttactga tttagcaaaa gaaatcatcg aactttatcg
     9481 tcgcgtatac agcgaataaa tacaacttct tttttgaacg gaagaagaaa aatttttgaa
     9541 cggatttttt attttgttat aaggagaact ctctttatat aaaaaactta taggaggaag
     9601 taaaaaatga acggactatc aagttggatg gagaaataca tcctgccggt tgccgcaaaa
     9661 atcggagcgc aaaaacattt agttgctttg cgtgatgctt ttatcggcac actgcccgca
     9721 acaatggcgg gatcagtcgc tgtaatgatc aatgcaatta ttcgtgattt accgcaacag
     9781 tttaacagta cctatgctga cagtttagca gcagacaaag gaatctttgc cgtattgaat
     9841 gtcatcatcg gaatcaatgg ttttgtctgg aacggtacac tagcaatcgc cggattgatc
     9901 tttgcctttt cttgggggta taatcttgcc cgagcttatg gagtaaatga tctagctggg
     9961 gggatcgttg gtttagctac cttgattcaa ggtatttcct ttggtccagc attatcagca
    10021 gcattagatg tgaatgttcc ttcaaatgtc gcagatgcaa tcaatagttc tgagattggt
    10081 gcaacgattg cagatggcac actgtcagtt ggattatggg gttggctaaa actagatcat
    10141 ttgaatggaa acgcttattt tacagttatg atcatgggag ctatttcagt cattattttt
    10201 tgtaaattga tgcttgccaa cattacgatc aaaatgcctg attcagtacc accagcagta
    10261 tctaaagcat ttgcagccat tttaccagcg acgatcgctt tatacgtcat tgctattatc
    10321 aattatatcg taggtcgtgt agctgatggg caactgatca ttgatttggt gcaaaaatat
    10381 attgcagaac cattcctagg attatctcaa gggttgggag cagtattgat cgtcacagta
    10441 tttgttcaag tattctggtt ctttggtatt catggaccaa atgtattggc accagtgcta
    10501 gagggaatct ggggacaagc acaactaatc aatattgata ttttccaaaa aggttataac
    10561 ggaaaaactg gtacaccagc cgtgttagat gcaatcgaag atggaaaagc ttatatgtgg
    10621 gtccgcggat cgttcgatgc ttttgcatgg tttggcggat caggcggaac gatcgtctta
    10681 ctgatagcta tcttgatttt ctctaaacgt gcagattatc taacagtagc taaattatcc
    10741 attgggcctg gtatcttcaa tatcaacgaa ccagtgatgt ttggtctgcc aatcgtattg
    10801 aatgcaatca tgtttatccc attcttgatt gctccagtag tagcaacagc aattggatgg
    10861 acagctactt atcttggcct agtcgctccg gtatcgcagc aagtcacatg ggtagtaccg
    10921 ccgttcttat tgtcattctt agcaacagga gcggattggc gggcaccgat cgtaacatta
    10981 gtatgtatgg tcgtgacttt cttgatttgg gcaccatttg tcatctctgc aaacaaaatg
    11041 gaccctgccg caggcgaaca acaataagat gaacgtgagg agcgggacgc tttaagtttc
    11101 gttcctcata atgaattttc gaggaggaac tgaaatgatt acaattgcca gtgcaatgca
    11161 acaagatgaa atcaaagaat tgttagaagg atacaatgaa gaaggaatga cttttacatt
    11221 taaagaaaaa caaggaatca agctgttctt tgaaacaagt gcagaagatc cggaagttgc
    11281 ggctaaaaaa gcaaaggaac taatcaaagc acagccttgg ggaacagtcc tttattttca
    11341 atcaacagct gtttagaaaa tggtttaaaa agataggatg gttgagatga taaaaaacgg
    11401 tttattttta tgtagtattg gttctttgat cgtgttgtat agtttgaatc cacattcgca
    11461 aaggtatgat ttgtatagta tggtcacagg tctttttcta acaggattag gaatctattt
    11521 cttcatgaag gggaaaaaaa gagaagaagc aaaggagaaa aataactaat ggaaatcacg
    11581 aaaaaattaa atattccagc atcgtttttt tacgataaag ttatggactc tgtccttttc
    11641 gatgtacgta aagcgaccgg caaatcagta actagaaaac agctgaaaaa tttggagtac
    11701 gtcaaacaat tctcgcaaaa taaccgggct cgcataaaaa tcgaagaagt cattgaaaac
    11761 cagtcttata agtttcgtac atcgacaacg aagaatgaat tcgtcgttca ttatcaaatc
    11821 aaaccattgg acgattcgac ctgtgaggtt cattacacag aaaaaatgga gtcttatggc
    11881 atgcttcaaa agttgaatga tatgctttta ggaacaatct tgatgtattt taaacggaga
    11941 cgtttcaaaa aaatgctaga tatgatcgaa gcaacgtatt aaatcaatga aacatggtac
    12001 tatttagtta ttgaaaaatg aagtaagcta gaaggaattt ttcataggaa gatagatctt
    12061 tcctgcgaat cctcactagc ttttttgtag gaaggggcag caaaatgaca aacaaagtaa
    12121 gagagctagg tgtatcttcg attgaggaaa tgtttgattt agccacttat gcatttaatg
    12181 gggcagatac acctgaaagg cgagaacgtt ttcgtacact tgcggagaat tcttggaatt
    12241 acggattttt tgatgaggag gatcggctaa caagtcaagt catggcgacc ccttttccag
    12301 tgaattttta cggacaagag tacctaatgg ccggcattgg ctatgttgct tcttatccag
    12361 aagcaagggg acaaggcggg atcaatcaga tcatggaaaa gatccttgaa gattgccgtg
    12421 atcgtaaagt aagcttatct tatctggcgc cattctccta tcccttctat cggcgctatg
    12481 gctatgaaca atcatttgat aaaatcagtt atcaactaaa cagtcgtgat gtgccgttta
    12541 tcaaaaaaaa atctggaaaa ataaagcgta tggattttga agatgcaaaa gctgcaatca
    12601 gaagaattta tgaacagatg ccggaaaacc aacgagctgg tctgaagcgc gaagactggt
    12661 ggtatacgta taaattcaag caaaaaggca attaccagtt tgctttgcat tttgatgata
    12721 atgaggaagc aacgggatat atcgtttatc agcttgcaac gtcttccttt attattgcgg
    12781 agtggggatt tttggatcat gatgcttttt gcagccttgt tcgcttcgta agttctcaca
    12841 atggtgcttt tgaaacattt gaatattcat gcggctacgg cggtaatgat caaaattatc
    12901 tattagaaaa tccatttgct tctgtaatga tcacacctta tatgatggcg aggatcgtag
    12961 atatttcttt gtttttggaa aattatccat ttaaaaagag acaagctgca tttgccctac
    13021 aaatagaaga agatcattat gcgaaatgga atgaaggaat cgtggaagta acaatcgaaa
    13081 atggaaaaaa tcatctctca aaagtagaac aaacaaaact cccaatcgtt cgaggaagta
    13141 tccaacatat cacgcagcta ttattagggt atcgtaaagt ggaagagttg gtattccaag
    13201 aaagaataca ggtgacaaaa gaatatgaag aaacgttaag ctcaatcttg ccacagcaac
    13261 agccaattct taatgactat ttttgataaa aaacgggtga tgacaatatt tttgtcacca
    13321 cccttttgtt tttcatttgg catttgaagg aaaatgttaa agtaaatcct cttttttcgt
    13381 aaatttgaat tttttgtttt cttttgtttt agggttttct tttttgtggt cttggattgc
    13441 ttctttcgta atcttttccc gatttttttt agatgaatct aagcgttctg cgtatacttt
    13501 ttcttttggc ttatcattca ttggaaagga cctccctaca ttatttcatt ctacctctag
    13561 tttatcatct gttaaggact agtggaaacg ttttgcctaa cttataagct gattttttta
    13621 gcagataagc ttgcaagtaa aaaacaaaca agctacaatt gatttattga aattgttcct
    13681 gtagctcagt aggatagagc aatcgcctcc taagcgatag gtcgctggtt caattccagt
    13741 caggaacgta caaataaccc ctgtatcctt tgcggtacag ggggttattt tgtataagta
    13801 gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag tatatttact
    13861 ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc catcaataaa cagtcgaaga
    13921 gaaaataggg aaaaattgat tactaaagaa aaacttacta ggtcgacggt gtagttgatt
    13981 ttcatacttc aatagattcg aattaaacga tttcgattgg cttataccag tcctatccaa
    14041 cgaaagatat atcgttctta actctagcgg tataacttga agctttacgt aaagccaatg
    14101 ggaatgaact ggagatgact ttttattatt tttagtaata gctgatgggt taatacttac
    14161 aactttcctt ttcaaagtac catataaaaa aacggtgggg ttgtttagcg aaataaagga
    14221 tctaagccaa tagcttagat cctttattct atgctttata ttattttttg catgtgtgcg
    14281 aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc catcttcacg
    14341 gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg tttgacttct
    14401 attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt tcacactgaa
    14461 ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata atgtattgaa
    14521 aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga cttctcctaa
    14581 acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc cttgttcggc
    14641 agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga tgatggtgcc
    14701 agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac tgtcaggtgc
    14761 tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag cattatagct
    14821 tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg taccgggagc
    14881 agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt ttgctaattt
    14941 ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag tcgttttgaa
    15001 aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga agacttttgc
    15061 tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg cttgagttgc
    15121 cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta ctcgatggct
    15181 atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc ttgctccttt
    15241 ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa tacgatccgt
    15301 tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa cgataacctc
    15361 agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg cctgttccac
    15421 gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt ctgcaattaa
    15481 gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa ttcctcctca
    15541 ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa caatgaggct
    15601 ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat gttactactt
    15661 gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa aacatgttac
    15721 aatgaaatta atcaatggtg gaagcgttat aaaaaaatta aggagattaa aaaatatggc
    15781 aagaaaaaag acgattacta gagaacagat tttggcagct gcttatgaag tagctgccac
    15841 cgatggattt acacgattta ctgcgagaaa catcgcgaac aaaatgaatt gttccacgca
    15901 accgatttat cttgagttta aaaatatgga tgacttgaga caagctcttt ttgagcagat
    15961 ctatgatcat ttacaatatg aagtgttcac tgttgagcat acagggaata cgattatcga
    16021 tcttgctttt aattatatcc attttgcaag aagagagaag aagttgtatc gttcactgta
    16081 cttagaagaa tatggtggag gaaaagagat gcagaatttc tcttatactt actttgtgaa
    16141 tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa gagcagatcg aatctttgta
    16201 taatgggaca tggatcatag ctactgggat cgcagctttg atgtcttcaa gcatcatcca
    16261 tccaactgat gaacagattg aaaagatgat ccaagacagt atagatgcta tcttgaaatt
    16321 caaagaacca atcgaaatcg attgaatata ctcaaaagtt ccacaaatca gtaggtaaca
    16381 agagatgtgt caaaataagg aaaagttcgt ttttcttaca gcgtatgcat ttttaactcc
    16441 cgaagaactc ttccatgaat gcaatgaata aaagagccat acagattgaa taaatctgga
    16501 tggctctttt attgcaagta tattaaattt ttgcgactag ttctttagcg aaagcttcta
    16561 aattttcgat atcttcttct tcagcattca gatccacttt aacattttcg gctccttttg
    16621 atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac cgatttgcag aattcatcgt
    16681 aaaaagtatc accagatccg cagacaccgt aaatttttcc caatagatcc aattcttgca
    16741 agtcttcata aaagtctacg atctcatcag gcagatcgcc atcatcgtat gtataagtag
    16801 ctactacgca aatatctgcc tcctcgaatt catctgcatc tacttgggta cattcgttga
    16861 tttcgacttc gatatccaga ttttcaaatg cttctgcaac aatatcggcg atttcttcag
    16921 tgtttcctgt catgctagca tatacgattt ttgctaaagc catgatgtgc ctcctcgttt
    16981 ataattattt aacaattatg aattatacca aaacatcatt gaaaagaaaa taaaacctaa
    17041 agacacctgg ggaatgtcat ttggctaaat gtatgccgct atgttaaaat gagagggatt
    17101 tgtaaaaagg agacgaaaat atgattactt taaaatcagc acgtgaaatt gaaatgatgg
    17161 cagaatctgg agctttatta gcagatgtac ataaaaatct gcgtgatttt ataaaaccag
    17221 gaatcacaag ttgggatatt gaggtatttg tcagaaacta tatcgagagt catggcggaa
    17281 ttgctgcgca aattggcttt gaagggtatg aatatgcgac ttgtatcagt ataaatgatg
    17341 aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa cggtgatttg gtaaaagtcg
    17401 atatgtgtat cgatttgaaa ggcggcattt ctgattcttg ttgggcctat gtagttggag
    17461 aatctacacc tgagatcgac cgattgatgg aagtaacgaa gaaagctttg tacatcggta
    17521 ttgagcaagc acaagtaggg aatcggattg gtgacatcgg tcatgctatc caaacttatg
    17581 tagaaggcga aaatctagcg atcgttcgtg attttattgg tcatggcgtt ggtcctacga
    17641 ttcatgaaga accagcagtt cctcattacg gagaagctgg aaaagggttg cggttgaaag
    17701 aaggcatggt tatcacgatc gaacctatgg ttaataccgg aacttggaaa atgaaaatgg
    17761 atcctaacgg ctggactgcg tatacaagag acggcggact ttcttgccaa tatgaacata
    17821 cattggctat tactaaagat ggtccaagaa ttttgacatc acaaggagaa gaaggcactt
    17881 attgatctat ccagtcaata ggtacgggag aggtacatga aagtttggaa caaaataaaa
    17941 caaaatgaaa atctgatgcg ctttattgag acgactcaaa agcgcatcac tgattcagaa
    18001 atgagtacga cctctgtcgt cgttgcttat tatttactct tgtctttatt tccattgatt
    18061 attgcttttg gtaatatttt accgtttctc cacatcgatc aagagactgt actgacctat
    18121 ttacgagaag tgattcctga gaccgtttac cagtttatcg gtcctgcaat caaagacctt
    18181 ttgacacaaa gttcaggagg cttgttatcc gtttctgcat tagcggcttt atggtctgca
    18241 agtcaaagta tcaatgcttt gcaaattgcg atgaataaag cgtatggcgt agaaaataga
    18301 aaaaattttt tgatcgtccg tttcttctca ctaattgtca ttgtcttgtt catgattgct
    18361 attagtgggg taactatcgt tcttgggttg ggacagctga ttttggatgc tattcagcca
    18421 atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa ctttgaagtg gccaatcaca
    18481 ttggtagctt tatttgtcat catgttcttg atttatttaa ttgtccctaa tgctcagttg
    18541 aagttgaaga cgatcattcc gggcacgatc ttcgctactg tcggctggat gctgttatca
    18601 caagtgttta gtatctatgc taggtatttt gcaacgagga tcagcggtta tcagatcata
    18661 ggaagtttta ttgtactcat gctttggctt aattttgctg ctacgatcat cattttgggc
    18721 ggaatcatca atgcagttgt tcaagaatac gtgacgggtc atcaaatcaa aaaacgtcga
    18781 gatccaagcc gaaaatggtt caataaattg aaaactaaat tttctcataa aaaaaagtag
    18841 aaacaagagt tcttattgta aatttatatc agtaatttat aataattatg actcttaatt
    18901 aaagtaggtg cccatatgct tgtttctttt agtatggtta taagattttt tctgacaatt
    18961 ttattatcac tgatattaac acctgtattc aaaatcattt cagtacaaac aggtatggtc
    19021 gacaaaccaa atgaaagaag aataaataaa gttccaatgc cttcagcggg cggactgcct
    19081 atctttattt catttgttat atcgacttta ttcttattcc gtaaaattat ccctcaatcg
    19141 tatattgtac cgatcttgat tgcttcttta gtaatcatag tcacaggagt gctcgatgat
    19201 aaatatgagc tgacacctaa acaaaaaagt atagggatct tgattgcttc tcttattatt
    19261 tattttgtag cagatatacg tattgattcc ttcacgcttc cttttattgg atatatccaa
    19321 ctaggctggc ttagttttcc cgtaacgatt ttttggatct tcggtatcac gaatgcggtc
    19381 aatctgattg acggtttgga tgggctggcg gcagggattt cattgatcgg tttaattacg
    19441 ataggaatca ttggatattt tttcctccat gcttctacag tgtatattcc agttgttatt
    19501 ttctgtcttg tagcaagtat tatcggtttt tttccttaca atttttatcc ggcaaagatt
    19561 tatttaggcg atacaggagc tctattccta gggtttatga tggccgtcct ttcactacaa
    19621 gggctgaaga acgtgacttt tgtttcatcg atttctttgc tgatcgtcat gggagtgccg
    19681 gtaacagaca cgttttttgc tatcattagg agaaaagcaa accgtgtttc tttttctaca
    19741 gcagataaaa aacatcttca tcaccgacta atcagtttag gctttactca taaaggtgct
    19801 gtcctgacga tttatgcgat ggctttgatg ttttctttca cagctatggt catgaattat
    19861 actggaagaa tcggaacgat catattgatt attgccatgt tgtttgctgc aattttatta
    19921 tttgaattga ttggtctgat caatgagaaa catcagttta ttttaaaaac attgcgattt
    19981 ttagggaata aagagtaccg tacgcaagta aaacagaaat atttgaagaa atggaaccgt
    20041 catatagatg aataacaaat taaaccagcc gatccttatt agtattgtga cggcaaacag
    20101 tgataaaatt tttcggacac tagataattt tatttcaact gtaaaagatg aaacagcagt
    20161 aaaaatccga atttttgaca acaattcact tcccgagtac aaaaaaagac taacagagta
    20221 taggaaatat ccctacatcg atatctattt tcatgatgaa aattccggat ttggttatgg
    20281 acataatcac aatctgatag ctagcgattc tcgctatggc attatttgta acccagatat
    20341 tttagtggat gaagagacag ttacagcatt ggtcttgtta ttgaaagaac atccggaatg
    20401 tgcgatgtta gcacctaaga ttcttaatga agatggaaca actcagcacc tcatccgtga
    20461 gcagctggct gtttttgatt acgttttgcg ctttgtgcct ttcaaatggg tcaaaaaaaa
    20521 gtttgacaaa cgactggctg tgtttgaatg ccgaggattg cctactgatg ctaatagtta
    20581 tgtacggatg atctcaggta gttttatggt agctgatatt gataaattta aagagataaa
    20641 ggggtttgat gagcgtttct tcatgtactt tgaagacaac gacttgtgtt tgagttttga
    20701 aaaagcaggt tacaagttat tgtacacacc cttttatgca gttatccatt tttacgggaa
    20761 gggtgcgcat cgaaatgcaa aactgtttcg cgtgtttttg acttctatga tgaaattttt
    20821 caataagtgg gggtggcgtt ttttctgatg aaaccagaaa tattagtagt cgttgtgctt
    20881 tatcagcaac tattcagtca atctccagct tatggaccat taagcaaagc acttagcgaa
    20941 aagcaaattc agcttattat ttacgataat agtcctcaaa ggcagcaaaa tgagctgttt
    21001 gaaaaagaaa atatcgttta tcatcatgat ccgcaaaatc ctggtttagc ggtggcttat
    21061 aattttgcgt tgtctcaagc agatgaagga acacgttgtc tcgtcactct ggatcaggat
    21121 acgaggctag tcgacgatta ttttgaacta ttgcgtaaag taacctttac agatgaatgt
    21181 gttgctgcag ttccgatgat tttttctggg agccgacaag tttctcccct atattcagat
    21241 cgttatatca atcgtacagc tcaagcagta gaagttgaag gcccaacagc tgaacgaatc
    21301 atggcaatca attcaggtgt tgcctggtct gtcaaatttc taaaaaagat tggcgggttt
    21361 aatcctgctt tttctttaga ttttttggat cattggctgt tttggaaagt ggatcagttg
    21421 gaaaaaactg tggagatcct tcctgtacga atggaacatg atctttcggt tttagactat
    21481 gaaaaagttt caagtaatcg ataccgttct attttacaag cagaaaatcg attttatcat
    21541 gaatatgatc aaaggcattt atccagtcac cgacgacaat tattgttaag aacagctaaa
    21601 cagttcttga ccgtcaaaaa ccggcatatc tggcggatga ctttgcgctc atatgttaag
    21661 aattggaagg tgtgaattcg tgcgttcggt ttgtatagct acctttaatg gaggcagata
    21721 tttaagagag cagttagata gtattttatc tcagctttca gcagaagatg aagtagtcat
    21781 ttctgatgat gggtcagtag atgatacatg ggatatatta actgaatacg cagaaaaaga
    21841 taagcgaatc cagctttttt cggggcctcg tcaaggattg atcgctaatt ttggttatgc
    21901 gatccagcag acgaaaggag atctaatctt tttggcagac caagatgatg tttggttgga
    21961 gacaaaagtg aaaaagatca ctgactattt tgagcagaat ccggatcagc tagtagtagt
    22021 ttctgattta atcattgtgg acagcgagct gcaagagatc catgattcgt atttttcgtt
    22081 tcgaaattcc aaagaaggat ggcttaataa tgtgataaga agtcactata ttggtgctgg
    22141 tatggctttc cggtcttctt taaaacccga tattttgccg atcccgtcag aagtgccgat
    22201 gcatgatatg tggattggtt tgctgggagg aaagaagact gggttcctaa gagaaccgtt
    22261 aactctgtac cgaagacatg atttaaacgc gagtgagatt gaaacacatt ctaaattacg
    22321 gcaaaaaatt tcttggcgtg ttcatctgat tacggcgttg atcaaacgaa aatggtttaa
    22381 acgttgataa aagatgttta aatccttaat atttccatga caaatataac aattgatgag
    22441 ataataacaa agtgaaattt gaaatcaaaa aggagagcag atatccatga agggaatcat
    22501 tcttgctggg ggcagcggaa cacgtctgta ccctttaaca aaggcaacat cgaaacaatt
    22561 gatgccgatt tatgacaaac caatgattta ttatccaatg tctactctga tgttggcggg
    22621 aatcaaagaa attctgatta tttcaacgcc acaagataca ccacgtttca aggaattatt
    22681 tggaaacgga aatgatttag gactgcagat cgaatatgca gtacaagaaa gtccagatgg
    22741 attggcacaa gcgtttatca ttggagaaga atttattgga gatgatagtg tctgcttggt
    22801 attaggggac aatatttact atggtggcgg tctgtctaaa atgttgcaac gagcagcttc
    22861 aaaagataca ggcgcgacag tatttggcta tcatgtcaat gatccagaac gctttggtgt
    22921 agtagaattt gatgagaata tgcaagcttt gtcgattgaa gaaaagcctg ctcagccaaa
    22981 atcaaattac gctgtaactg gcctttattt ttatgacaat gaggtaattt ctatcgctaa
    23041 aggtatcaaa ccttcagaac gtggagaact agagattacg gatgtcaata aagcatattt
    23101 ggataaagga aaactatccg tagaacttat gggacgcgga tttgcttggc ttgatacagg
    23161 aacacatgaa tcattgcttg aagcatctac ctttatcgaa acaattgaaa aacgtcagaa
    23221 cttaaaagtg gcttgtttgg aagaaattgc ttaccgtatg ggctacatcg ataaggaaca
    23281 attgctggcc cttgcacagc cattgaaaaa aaatcaatac ggtcaatatt tattgaattt
    23341 ggccgctgaa taaggagtcc ttacagatga aagtaacaga tacaaaatta acagatgtca
    23401 aaatcgtaga aatggacgtc tttggcgatc atcgcggttt cttcacagaa agttattcaa
    23461 aagcaaaatt tgcagaacat ggattgaaat atgactttgt tcaagacaac cattcactat
    23521 cagctgaagc tggtgtcctt cgggggcttc atttccaaaa aggagaagct gcacagacaa
    23581 aattgattcg ggtagtcact ggagcagttt tagatgtagt agtggatatc cgcaaaggta
    23641 gcccgactta tggtcaatgg gacggattta tcttatctga acataatcat cgacagttgc
    23701 ttgtacctaa aggatatgcc catggattcg ttactttgac accaaatgtg aacttccttt
    23761 ataagtgtga taattactat aatgcagaag cagatggggg catcgcattt gatgatccag
    23821 atttagcgat tgattggcca attgatccat caagagcgat tatgtcggaa aaagatcacc
    23881 gtcatccgac attaaaagaa tttgaagcag aaaatccatt tgtttacgga gaaatctaag
    23941 aattaaggag aaattttctt atgaaaaaca tcattgttac cggaggtgcc ggattcatcg
    24001 gctctaattt cgttcattac gtggtaaaca atcatccaga agtgcatgtc actgttttgg
    24061 ataaactgac ttatgcagga aacaaagaga acttggccgg acttcctagc gatcgcgtag
    24121 aattggtcgt aggagatgtt gcagatgcag aattagtgga ccgtctagta aaagaagcgg
    24181 acgcagttgt tcattacgcg gcagaatccc ataacgataa ttcattaaaa gatcctttcc
    24241 catttgtaca aacgaatatc attggtacgt atacactttt agaagcttgc cgcaagtatg
    24301 atgtacgcta tcatcacgta tctactgacg aggtttacgg cgatcttcca ttacgtgaag
    24361 acctgccagg acatggggaa ggcgaaggag aaaaattcac tgcggaaaca ccatataatc
    24421 cttcaagtcc atattcttct acaaaagctg gttcagatct gttagtaaaa gcatgggtgc
    24481 gttcttttgg cttacgtgca accatttcaa actgttcaaa caactatggt ccttatcagc
    24541 atattgaaaa atttattcct cgccaagtaa cgagtatctt aagcggtatt cgtccaaaat
    24601 tatatggcga aggaaagaat gttcgtgact ggatccatac gaatgatcat tcttcagcag
    24661 tgtggctgat tttgacgaaa ggcagaattg gcgaaaccta tctgatcggt gcagacggtg
    24721 aagaagataa taagaccgtg atggaattga tcttagaaat gatgggccaa ccaaaagacg
    24781 catacgacca tgtaaacgac cgcgcagggc acgatttgcg ttatgcaatc gattcgacaa
    24841 aattgcgaga agagctaggt tggcagcctg agtttacgaa cttccgtgat gggttggctg
    24901 acacgatcaa atggtacgaa gaacatgaag actggtggaa aaaagaaaaa gaggccgttg
    24961 aagcagcata tgccaaaaat ggacaataat acagaggaaa tttcactgta ttaatggaaa
    25021 aacacatgtg aggcaggcgc tcgcctgtct cttttttaaa ataaaaatca aggagcggat
    25081 aaccatatgt ttttattaac tggaggaaat ggacaattag gtacagaatt gcgccattta
    25141 ttagatgaaa aaaatctgcc atatgtttca acagatgcaa aagacttgga tatcacagat
    25201 gctgagaaaa caatggctta tattacagaa ttaaaacccg atgttatttt ccattgcgca
    25261 gcttacacag cagtagataa agcagaagaa gaagcaaaag aattagatga gaaaatcaat
    25321 gtcgatggca caagaaatgt agcacttgca gcaaaagctg tgaatgcaca attcgtctat
    25381 atcagtacag actatgtttt cgatggaaaa aacaaaaatg tagaatacga agtagacgac
    25441 caaacgaatc cactaaatga atatggtcgt acgaaattat taggcgaaaa agcagtagaa
    25501 gagattttag aagactatta tatcatacga acttcttggg ttttcgggat ctatggacac
    25561 aatttcgtct tcacgatgca acgcctagcg gaaacccgcg acaaactgac tgtagtaaat
    25621 gaccagtttg ggcgaccaac ttggacacgt actttggcag aatttatggt atatgtcatc
    25681 gaagaaaaag caccatttgg tatttatcat ttgtcgaacg aaaatagctg ttcttggtat
    25741 gagttcgcaa aagaaatatt gaaagataca gatgtagaag ttgcacctgt tacgtcagaa
    25801 gaatttccgc aaaaagcaac acgtccgcag tattcagtca tgagcctgaa aaagacagaa
    25861 gcgttaggtt ttgtcatacc aacttggcaa gaagcacttg cgcaaatgct ggaagctgcc
    25921 aaaaaaatga ataagtaatt tcctttttat caaatagaat ttggagcatg atatggaaaa
    25981 acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aatcaggcag attcgaattt
    26041 ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca tcgtggtcat
    26101 cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg tgtcgcaaag
    26161 agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc ggtcagacga
    26221 atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttt cgttggtgaa
    26281 cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc ctgtaaagga
    26341 tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa gagatcgagg
    26401 actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat tcgaagtact
    26461 gatgatatta acgaagagga aaaaagctct atcgctaatc ggtgcatttg cgctgacatt
    26521 ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt tctttacttt
    26581 gggactgatg attgcttttt atcattattt ctacaatcat gataaaaaat ggctacgaac
    26641 gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga tttacccagc
    26701 ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc ttatttacta
    26761 tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg cagttttatt
    26821 tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt tagcttcttt
    26881 gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga ttggcgaatt
    26941 tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt cgaataactc
    27001 tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc catttgtgtt
    27061 atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga ttttttgtct
    27121 gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct
    27181 gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt gtttattatc
    27241 gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt ataaattcat
    27301 tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga aaatggataa
    27361 ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga ttttagcttt
    27421 tgcattattt ggctggagac gcttgtttta cctcgctttt gtcgccttag ttatcgtatc
    27481 tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa aaacactggc
    27541 aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt ctgaagatga
    27601 attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac gcttttatcc
    27661 agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt attataatcg
    27721 gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt tagatcgtcc
    27781 agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga tcgactatgt
    27841 gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt tcacgcagct
    27901 atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg attatccaga
    27961 tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg ctagctgaga
    28021 ataatcctga aatattagta gaaaggagag tgaagataat tcaagcaatc gtacaaaaat
    28081 ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttgct gacgctagtc ttttttgttt
    28141 ggacagcagg ggtaggtttt ccagcaactt tgtttatata taacaatagt tcattactta
    28201 tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa ggcgtcgatt
    28261 ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt cgggaattaa
    28321 gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt tgtttagtaa
    28381 ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc tttacggtct
    28441 tcctcggaat cacgttatat cgtgtattta cagagatcca agtaccagaa ggacaaagca
    28501 tctgggctcc aggcaattcg ctttctgata tttggatcaa tacgaataca atcggaagtt
    28561 ctttgatgac tcttgcttta ttgatcagtg gatttgccag ttcttttgaa cgatggtatg
    28621 ttcgaatcat cggtgggata gcagtcgttg cagccttttt aggtatttgg gtctgccaat
    28681 ctagaggtgc attagtcgcg ttgattgttt ttgcgatatt ggatctttta cctaaatcgt
    28741 tgatgcgtgt cattcgtgcg ccatttattg cctacacggt tacgattctt ttagctttgc
    28801 cgatttctta tctggcggct gtctctgaaa aagtcaattt gtttaccggt cgagaagata
    28861 tttggcataa attctatcag acgctaggag aaaaatctga acaagtttta ctaggaatga
    28921 aaacatttat cttccagcga ggaaaccaat ttttaggaaa ccacaatagt tataattcta
    28981 ttttgaatat ctatggattg ataggatttg ggattgctgc tttgctgctt atccttttta
    29041 ttggtcgctt aacgttgaaa gcagatttat ccaacgggca gatgactttt atctgggcct
    29101 tttttgcggt gatgatgcag tcatttatgg aggatacatt gacttcatac cgatgggttc
    29161 cgattattta tatcctgttg gctatggccg ttcatcgata tgatgaacca gaagttacgg
    29221 aggaattcta tgttatggaa gaggcatatg acgatatgac ttatgatgat acatcttatg
    29281 aggaacaacc agatagcgct cattcttcca ggatccaacg ctatcattga taggcacaaa
    29341 atacgagaga ggctgtgaca accgtcgcag ccttttttgg tttattgcaa ttgtctagca
    29401 tcttctgtaa aatagaaacg ttagagaaaa tcttgtatca tagaaaatta agaaagaaat
    29461 aagaacgcag ctcggtacca aaaatatggt aaaatggcac ttgactgtaa ttcactgaaa
    29521 atcgcttgga ggaacacaaa tgtttaaaga tttgtattta tttatgaagg acatttatca
    29581 gaacagaaaa ttactgctac agttttcgat caatgacttc aaatcaagat atgcaggatc
    29641 gtttttagga atcttatggg cgtttatcaa tccgctattt actgtattga tttattggct
    29701 ggtatttggt gttggactga aagcacaaat gatcgatgca aaatacccat ttatcgtata
    29761 tttagttacc gggatgattc cctggttctt cttctcagat gcatttgcat caactacggt
    29821 tgtttttcgg gaatatactt atttagtaaa gaaagtcgta ttcaatattc gtatcttgcc
    29881 cacgacgaaa atcctatcca atctgtacac ccatttattc ttcattctga ttggcatagc
    29941 tgtcgcgctt ataaatggta tatatccttc agcaatgtct ttacagctga tttattattt
    30001 attttgcatg tgtgctttct tgacaggatt gacttggctg acggcatcga tccaaccatt
    30061 tttacctgat atcatgcaat taattacgat cgtgctgcag ttgatcatgt ggacattacc
    30121 gatattatgg agccctaatc agtttgattc aggtcttgta agcatattga aattaaatcc
    30181 gctgtactat gttgttcaag gttatcgtga gtcattttta agtgaagctt ggttctggga
    30241 gcatggaaca tatactttgt atttctgggt tttcacgtta gtaatgttcg taatcggctc
    30301 tgcagtgttc cgtagattga aaccacattt ttcagatgtg ctgtaaggag aatagctatg
    30361 acagaatatg caattagact aaaagatatc acaaaatctt ataatatgta cgcaaaacct
    30421 tcggatcgat ttcgtgaagc cctcaatcct tttaagaaat cctatcatga tgtattttat
    30481 gcgttgaaaa acgtgaatgt agaaataaaa aaaggtgaga tgatcggttt cgtgggagaa
    30541 aacggatcgg gaaaatctac aatgttgaaa atcattacgg gagtactgac accaacatcc
    30601 ggcacgatgg aaatcgaagg aaaaatctca gctttgctag aactaggatc aggattcaat
    30661 cctgagtatt ctggctatga aaatatctat ttaaatggaa tggttctagg attttcaaga
    30721 gaagaagtcg atgaaatggt cgatgatatc attgaatttg ctgacatcgg cgaccatatt
    30781 tatcaacctg taaaaaccta ttcaagtggg atgttcgttc gtctagcttt tgctgtagcg
    30841 atcaatgtga atcctgatat tttgattgtg gatgaagcat tggcagtagg agatcttgaa
    30901 tttcaactaa aatgtatgga aaaatttaca gaaatcaaga actcgggaaa gacgatttta
    30961 ttcgtttctc atgatattag ttcgattcgc cgtttttgtg atcgttccta ttggttgaaa
    31021 aatggaaaag ttgtcgaata tggtgatacg atggaagtaa cgacgaatta cgaaaacttt
    31081 ttgaagaaaa aatcagttaa aacagtagat cgaaataaaa accaagtaga acgcttcgca
    31141 gctccagata tcgtagacgt gacgaaagcc gaattgttgg ataaagataa aaatccagtg
    31201 gatatgctgg aacaaggaga aaaactatac gttaaagtaa cctatgaagt aaaagacgat
    31261 acaatcaaaa atccagtttt aggaattgct ctgcgtacag tcgacaattt ttatgtgtgc
    31321 ggactcaata ctctactaga tggtatcaag atcccttgga aaaaaggtga gaatatcttt
    31381 tatctggagt atgaaaagtt aggtttgtta gctggtgaat attattttga cgttgcggtc
    31441 tttgaagaaa atgcaacggt tcctttggta tacaagacaa aatacatgaa cttgtttgtc
    31501 agcggttctt atatcggaga aggcatcgtg gtcttagacc ataaatggga agaagggact
    31561 catagcaatg aaatatgatt ttgaaatgga cctagatgaa caaagcagtg tgggaaaaat
    31621 tgccgcacag atcaaaccag gaagtaaagt tttagagttt ggtcctggaa acggccgatt
    31681 aacgaaacat ttgatcggag caaaacaatg tgaagtgagc attgtcgagc tagataagga
    31741 attgttcgat tttgtcagcg agtttgccca agatggattt tatggagata tcgaaagttt
    31801 tgaatgggca aactattatg ctggacaaac atttgattac gttttgtttg ccgatgtttt
    31861 agaacatttg gtagatcctg gaaaaacgtt gaagaaagtt agagaatttt tgaatgaaga
    31921 aggagaaatt ctaattacat tccctaacct tgcgcataat tctgtcatga ttgatttgtt
    31981 caataatcaa ttgccatggg cttcttatgg tttgctagat gaaacccata attcttttta
    32041 tactcatgat ggcttccaaa aagtttttga aaaagcagga ttatacatca atattgaaga
    32101 ttatttgtac ttagctgtag gtgatacaga attaaaatca acttatgaag aattgccgga
    32161 agctgtacgt tatgatttca aaatgcgacc atttggcgaa gtctaccaat acttcttctc
    32221 attgatgaaa catccagtag cacaaagttc cattgcgcag ccgcaaaatt ctaattatgt
    32281 gaaagtatta gaagtaatcc agcaaacgaa acaagatgaa ataattcaac aaataccatt
    32341 caataatttc acaggggaaa atgagacact aagtttccat gtatcagaat tagcagaacg
    32401 aatggtgttt cgcttcgcgc agcaacctag ctttatcgaa ttcagcgcag aagctgctgg
    32461 agaaaaactc acatttatcg attcaaatgc tgtagtcaaa acagtaaatg attgttattt
    32521 gtttgatggt aaagatttac cagagttctt tttaacggat attgcaggga aagaagtgac
    32581 tatccattgt cactatcgtt ttatcggaga attgacacca acaatgaaag aattgctgga
    32641 aacaatccgt ccaatggctg aagttacaaa gcagctttct gagaaaaatg atgaattaga
    32701 aagagaaaat cattatctta ttgagaataa tacaagatta gatcagacgt tgaaaacaac
    32761 cataaatcgc tattgcacgt tgttggaaag tgatgaatgg acaatcaaac atagattagg
    32821 gcgacgtaag aaagaaacat cgaaaaaaat ccaagaaaaa gagctttctc tatgtattga
    32881 cgaaaaaatc tgggatgcag aaacaaagat attgaaaatc atcgggtggg gaatcgctaa
    32941 ttcggatcgc caaccattgt cctataagtt atcagccgac caatcaccat tttttgaagc
    33001 aattcctgtt ttacgagaag aagtcaatca agcaaaacag ctagctgaag gagcaaaagc
    33061 aggatttgaa ctgcggatcc tttgcgagaa ggaacgttca ttcttagttg aagcagtggc
    33121 tcaaaatggt caatcatgga tcattgaaat gtaaataatg attaacttat aaagataagg
    33181 agtaaacgaa tcgtgcaaaa aaaagaaatt gccgtattta tcgatcaaat cactcgtgaa
    33241 cgggccactg gcgatttgct tattgtgggc tgggcaattg atgaagtgac caaagaaatc
    33301 cctacgataa aggtagaaaa agaaaatgtg attgctgaag caacacatgt cgtaagattg
    33361 gatatcaatc atttatataa tcttgatgtt aagacccaaa gcggttttaa ggtacgttta
    33421 tcagggaaaa tgagaggaaa agcaatctta gacttccaaa cagcaagaca tcaaaatggc
    33481 atagctgtga aattaaacgg taaatatcct tatgatgacg gcattgaatc ttcatgggaa
    33541 agaaaaaaaa gattactgaa aaaagggata aattatgcaa ggactcatgg cgtaaaaaaa
    33601 gcaatccgcc gggtcaaact ggaattgaaa ccaggatcga tcgactatgc agagtggatc
    33661 agtcgtcatg agaaacctga tctgaaagag caaaggaaag aagtacaagg atttgcctac
    33721 cgcccattga tttccatact tatgcctgtc tataacgttg aaatcaaatg gctcgaaaaa
    33781 tgcattgatt cggtacttga tcaaacgtat gatcactggg aactatgtat cagtgatgat
    33841 gcttctactg atccagctat ccgaaagtgt ctagaatcct atcaagcaaa agatgataga
    33901 attaaagtcg ttttccgaca agaaaatgga cacatcagtc tggcaactaa ttctgcattg
    33961 gaaatggcag aaggagagtt tatagcgctc ttagataatg atgacgaatt acctccattt
    34021 gccttatatg aagtggcaaa agtgctaaac gtacatccag aactggattt gatctacagt
    34081 gacgaagata aaatcgatgc agatgggaat cgctttgacc cgcacttcaa agcagactgg
    34141 tctcccgata cattgatggg aaataattat atctctcact taggcgtata tcggacaagc
    34201 attgttaagg aacttggcgg tttccgtaaa ggatatgaag gctctcaaga ttatgatttg
    34261 gttcttcgtg tgacagaaca aattcctgca gaacacattt accacattga ccgtgtcttg
    34321 tatcattggc ggacgatccc gggatcaact gcaagcaatg gagaagctaa aagctacatc
    34381 tatgattctg gagtgaaagc attgacagat gctctatcta gaagaaatat caagggaagc
    34441 gtacatcctg gcagaatttc tggtttttat gaaatcactt atgatgtttt gcaagaagac
    34501 ttggtcagtg tgatcattcc aactaagaat ggctatgaag atctaaaaac ttgtgtggat
    34561 tcgatcatcg aaaaaacgtc ttatccaaat tatgaaatca ttattgcaga taatggaagt
    34621 acagatccta aaatgcaaga attatttgca gaatacaagc atcagctgaa agaccgattt
    34681 atcgtcgaat taattgacat tccattcaat tattcacgta tcaacaatct ggcagcagaa
    34741 aaagcaaacg gcaaatactt tttattcttg aataacgata cagaagtgat tgaacctgac
    34801 tggatgacag cgatggtttc ttatgcacag tttgatcgaa tcggctgtgt aggagcaaaa
    34861 ttattttatc cggatgatac aacgcagcat gcaggtgtat tattagggat cggtggcgtt
    34921 gcaggacatg cattgaataa ctatgatcga acacattgtg gttactttgg ccgattggtc
    34981 attgacgtca attacttagc agtcactgca gcttgtatga tggtcaaggc agctgacttc
    35041 aatgctgtca atggatttga tgaaatatta gaagtagcat tcaacgatgt tgacttgtgc
    35101 ttgaaagttt atgaactggg tcgttacaat gtctatgcac atcaagcaga attgtaccat
    35161 ttcgaatcta aatcaagagg ttatgaagat acaccagaaa aacaaagacg ttttgctggg
    35221 gaaatcaaaa aaatgcaaga taagtggcct tcttatattg ctcatgaccc attttataac
    35281 gataatctaa ctaaagaagg aatcggcgat ttttcgttga gacctgattg attaaaagaa
    35341 ctgtattttc atttttatta atgaaaatac agttctttta atttaa
//
LOCUS       DADQCX010000019        35309 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.019, whole genome shotgun sequence.
ACCESSION   DADQCX010000019 DADQCX010000000
VERSION     DADQCX010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.019"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(369..995)
                     /locus_tag="J8R83_000876"
     CDS             complement(369..995)
                     /locus_tag="J8R83_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574023.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(1290..1625)
                     /locus_tag="J8R83_000877"
     CDS             complement(1290..1625)
                     /locus_tag="J8R83_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAZ9574024.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(1612..1896)
                     /locus_tag="J8R83_000878"
     CDS             complement(1612..1896)
                     /locus_tag="J8R83_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAZ9574025.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(1952..3475)
                     /locus_tag="J8R83_000879"
     CDS             complement(1952..3475)
                     /locus_tag="J8R83_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAZ9574026.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(3468..4643)
                     /locus_tag="J8R83_000880"
     CDS             complement(3468..4643)
                     /locus_tag="J8R83_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9574027.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(4647..4832)
                     /locus_tag="J8R83_000881"
     CDS             complement(4647..4832)
                     /locus_tag="J8R83_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574028.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(4798..6492)
                     /locus_tag="J8R83_000882"
     CDS             complement(4798..6492)
                     /locus_tag="J8R83_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAZ9574029.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(6489..6962)
                     /locus_tag="J8R83_000883"
     CDS             complement(6489..6962)
                     /locus_tag="J8R83_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAZ9574030.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(7031..7186)
                     /locus_tag="J8R83_000884"
     CDS             complement(7031..7186)
                     /locus_tag="J8R83_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAZ9574031.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(7320..7700)
                     /locus_tag="J8R83_000885"
     CDS             complement(7320..7700)
                     /locus_tag="J8R83_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAZ9574032.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(7704..7919)
                     /locus_tag="J8R83_000886"
     CDS             complement(7704..7919)
                     /locus_tag="J8R83_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574033.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(7922..8329)
                     /locus_tag="J8R83_000887"
     CDS             complement(7922..8329)
                     /locus_tag="J8R83_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAZ9574034.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(8595..10070)
                     /locus_tag="J8R83_000888"
     CDS             complement(8595..10070)
                     /locus_tag="J8R83_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAZ9574035.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(10060..10908)
                     /locus_tag="J8R83_000889"
     CDS             complement(10060..10908)
                     /locus_tag="J8R83_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAZ9574036.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(10945..11307)
                     /locus_tag="J8R83_000890"
     CDS             complement(10945..11307)
                     /locus_tag="J8R83_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574037.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(11607..12231)
                     /locus_tag="J8R83_000891"
                     /pseudo
     CDS             complement(11607..12231)
                     /locus_tag="J8R83_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(12228..12539)
                     /locus_tag="J8R83_000892"
     CDS             complement(12228..12539)
                     /locus_tag="J8R83_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574038.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(12583..12876)
                     /locus_tag="J8R83_000893"
     CDS             complement(12583..12876)
                     /locus_tag="J8R83_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574039.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            13070..13717
                     /locus_tag="J8R83_000894"
     CDS             13070..13717
                     /locus_tag="J8R83_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574040.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            13778..14923
                     /locus_tag="J8R83_000895"
     CDS             13778..14923
                     /locus_tag="J8R83_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9574041.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(15004..15309)
                     /locus_tag="J8R83_000896"
     CDS             complement(15004..15309)
                     /locus_tag="J8R83_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAZ9574042.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(15334..15765)
                     /gene="ruvX"
                     /locus_tag="J8R83_000897"
     CDS             complement(15334..15765)
                     /gene="ruvX"
                     /locus_tag="J8R83_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAZ9574043.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(15762..16028)
                     /locus_tag="J8R83_000898"
     CDS             complement(15762..16028)
                     /locus_tag="J8R83_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAZ9574044.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(16283..17008)
                     /locus_tag="J8R83_000899"
     CDS             complement(16283..17008)
                     /locus_tag="J8R83_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAZ9574045.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(17369..17439)
                     /locus_tag="J8R83_000900"
     tRNA            complement(17369..17439)
                     /locus_tag="J8R83_000900"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17405..17407),aa:Gly,seq:ccc)
     gene            17556..18308
                     /locus_tag="J8R83_000901"
     CDS             17556..18308
                     /locus_tag="J8R83_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAZ9574046.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            18324..18803
                     /locus_tag="J8R83_000902"
     CDS             18324..18803
                     /locus_tag="J8R83_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAZ9574047.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(19054..20634)
                     /locus_tag="J8R83_000903"
     CDS             complement(19054..20634)
                     /locus_tag="J8R83_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAZ9574048.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(20627..21370)
                     /locus_tag="J8R83_000904"
     CDS             complement(20627..21370)
                     /locus_tag="J8R83_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574049.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(21546..22322)
                     /locus_tag="J8R83_000905"
     CDS             complement(21546..22322)
                     /locus_tag="J8R83_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574050.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(22570..23406)
                     /locus_tag="J8R83_000906"
     CDS             complement(22570..23406)
                     /locus_tag="J8R83_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAZ9574051.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(23417..24346)
                     /locus_tag="J8R83_000907"
     CDS             complement(23417..24346)
                     /locus_tag="J8R83_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAZ9574052.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            24538..24891
                     /locus_tag="J8R83_000908"
     CDS             24538..24891
                     /locus_tag="J8R83_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAZ9574053.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(24965..25621)
                     /locus_tag="J8R83_000909"
     CDS             complement(24965..25621)
                     /locus_tag="J8R83_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAZ9574054.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            25847..27781
                     /locus_tag="J8R83_000910"
     CDS             25847..27781
                     /locus_tag="J8R83_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9574055.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(27867..29090)
                     /locus_tag="J8R83_000911"
     CDS             complement(27867..29090)
                     /locus_tag="J8R83_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAZ9574056.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(29084..30982)
                     /locus_tag="J8R83_000912"
     CDS             complement(29084..30982)
                     /locus_tag="J8R83_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAZ9574057.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(30976..32094)
                     /locus_tag="J8R83_000913"
     CDS             complement(30976..32094)
                     /locus_tag="J8R83_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAZ9574058.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(32177..33010)
                     /locus_tag="J8R83_000914"
     CDS             complement(32177..33010)
                     /locus_tag="J8R83_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574059.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(33003..33919)
                     /locus_tag="J8R83_000915"
                     /pseudo
     CDS             complement(33003..33919)
                     /locus_tag="J8R83_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            complement(34146..35270)
                     /locus_tag="J8R83_000916"
     CDS             complement(34146..35270)
                     /locus_tag="J8R83_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9574060.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT        10592 a         7125 c         5776 g        11816 t
ORIGIN      
        1 ggaagagact gtgaagtcaa cgttttgacc tgattattag agaaacaaat ggcaaaatag
       61 ttcttcatat ttcgccgttt ttcgagcgaa tgccgagggg cagctgattg aacatcgttt
      121 atttggaaaa agggattgtg acaagacgtt tgtcacaatc ccttttttta tatcttatta
      181 attcattctt ttgttctatt cttcttcttc cgccatgaat gagaaaccca tatcaaagaa
      241 ctataaaggt tatcaaaaca gcgtttatga ctaaatgaat tagagttatc tatcactatt
      301 tttcaagcga tttaaaccaa atggcataca atatggcata caaaaacttc aataagccgt
      361 gggggttttt aaatttcttc ttgttcttta aaatcaatga gtggagctac ataatttgaa
      421 tccacttttt caaacgtcac tttttgcatc gacgaatgtt ttctttccca agataacgta
      481 aatagatttg actctggact tataaagtct acttcacctt ctagtattac tttcttatgc
      541 aaatattcct ctaataaata tagacttgct aaagcataca acacattttc caaatttgct
      601 tccttataat ttgaagaacg accatgtttt actctgttat atattttcca ccaatctggt
      661 gtatcttcag gccacccatc tccaaaaggt tttagtgaag tcaatgttaa agaattcata
      721 accctaacac cattatccaa acacattaat tcgctagatt taataacagc tttaaaatca
      781 gttatgcttt tattgctact gctatcaaat ccgcaaagtt ctttgaaaat aatctcacac
      841 tccgaaccaa tcgctagtag tagtttttga tattcaatag agaatgtttt gaaattattc
      901 tcatcgagca tcacaaaatc tgtggtatta ataaactcat tttctaaatg tagataatac
      961 ttccaataaa aatttgtaaa ctctgctttg tccattaaat cacctctttt gaattataac
     1021 aaaaaaaaca cgtccacaac agacgtgttc tttgatttct acacaatcag cttgccaaaa
     1081 ccatccaatc agtcctagca tgcctgtatt aaaattgaac gttcatcatc tatcatcttt
     1141 cttagtccag catgtttgca accacaccta caattttcag tccaacaata gatttcgact
     1201 agctaagtct tgcaaaattc aggcagctaa cccttcattt actaccttaa ttatactaaa
     1261 tacccacaac gtttacaagt gtaatcattc taagaaatct gtttagctat gatcgttgta
     1321 taatctttaa acgccgttcc ttcattgatt gaaataattt tataactctt gtttttccaa
     1381 gctactttca tatcgtttgt tagttcataa tcttgatcgt atcgaataat aaacgtcaac
     1441 gttccttcaa gaatggtacc tacactagca agcacgtctt ttagcatttg tgaacgcaca
     1501 ttagcccaac attcaaatac agtttcttca ctatccacca tctgcccatc ttcatctttt
     1561 acccgttttg tctttttaaa cttgactctc tcagtcaatt catttacatt cttaatgatt
     1621 ggcataataa gcacctctca tttgttgtac taatgcttgt accgttactg gtatccgttc
     1681 gctgctggct tcttgacggt tcaaatacca atgttgagta agtaatgaca ccgccaaatc
     1741 aaattgctga taattatcca tatctttatc cgttgcgcta ctatcaatag cactttttat
     1801 atattcgcct gctgtatcaa tcaattgttg aataaagtca tcatcaatag tgtgatcgat
     1861 ccgcatactt ttttttatgc tatccaaaat taccatttta tctctcctaa tgaaaaaaag
     1921 gcagtgggat aaaccgccgc ccaatatttt tctatacttt tggtgttaca actggcgtaa
     1981 actcaatata cactgaagca ttttgatcaa ttttcttata atcgttgcga acgatcactg
     2041 caagtccttg tgagtagtaa tcgaattttt cccattgagt cgttacttga tttctacgag
     2101 caacaaagat agattgtgca atatccccca taatcatagg gaatgttcca gctttaggat
     2161 tggcaaacaa tgtatctgca atcaatacta ctggcatacc gaataatgat ttaccactag
     2221 gtgctgtcac atcgggttgt aaaatgtaac gtccatctga atctttcaat gtatctaggt
     2281 ggtaatatcc gctttggttt agaattacca ttttatttaa tgctgggtct aatgccacat
     2341 tgtatagttg tttcaaatcg tccaacgtag cagccgtttt cttagtgaat gtttttaata
     2401 aatccatgat atgcttattg tcagtgtttt ctaccaattt cgctaactga tctttgacct
     2461 cttgtacaat attcactgct gaatcttcca caacctcatt tgataaggca atcttaccag
     2521 cacgagtttc tactttataa tcaactgaag taaacatttc agcgtcaata tcaccaattt
     2581 cagcaagttc agcttttgtt gctaacactg cttgttggtt agttgctact ggatatttac
     2641 cttgtccatt tgatactgtt tttactgttg catattgagc taagttataa tttgaacgtt
     2701 tcaaatcaaa gacttcaccg attacttctt cgggaacaac tgccgctgca tttacagtag
     2761 tgactccatc acgcacttcg ccttgtgaac ggatatattc ttcataccca cgcaattctg
     2821 ttttttcgtt atcgattaaa gttttttcca tgttattact ctccttttgt gctttagaag
     2881 tggattctaa gctattgttt gtttgttttg cttggttgtt actcataaac gattcgtaag
     2941 aacgcttatt tacttggaca tttgatgaat cataagcggg aacggtcacg acactaattt
     3001 cattaagtgc tttgatttta tctattgatc gttcaattgt gccatcttct tttttgtcga
     3061 atgaatctaa tccaagcacg aacccaaagg acatagaatc aacaacccct tttgagatat
     3121 tctcatacac atcatttgaa taggtcgtgt cggttagctc tgcttcaaaa tgtaatcctg
     3181 tatcatcgac attcaatttc aacgtacctg ctttgacact agctagtggc tttgaataat
     3241 cgtgtccata taataagaac acatttgata aatccacctc ttttaatgct tcgggtgtaa
     3301 tcacttctac aaagccgcct aaatcttttg acggttgccc gaatttcaac gcatagcctg
     3361 aaatagtttt gccgtctgtt ggttgttttt cattttcttt ctctactttg ggagaatcgg
     3421 ctgttagctc agcttcttct gtcagccgtt tttccttttc ttcttcatta ttcaactggt
     3481 gtaactcctt cctgttcttt taattgatat ttctccaacg tatctaaata cgtaaagttc
     3541 aaacttgcta gtaaacgatc gccaccatcc atggggggta gccccatttt cgaccgcccc
     3601 tcattaatcg tgagaagtga ccctttgacc tgatccaata cattttttac ttttgtttca
     3661 ggatcagtct ctagtaactg atcggaatta aagcggatat tggtttcaag tttcgtatct
     3721 aattcactca caaacacatt aaagtaatga atcagcgtac tttggatata ctggagatta
     3781 ctttgaacgg tgctagaatg ttcattttca acgcctaaac gctcaatcgg tacaccaaac
     3841 gccttggcaa tttgttttgt gttccaatca ttggaattga taagcttcaa aacatcggtg
     3901 tttatttcta atgttttgta gtccattgtt tcatcaagaa tgatcgttct aagagcatta
     3961 tctccactac ttgaaccgtt ggcttcttca aacttttcac gaattgcgtt ctttgctgat
     4021 ccgtctaaat ctgacttatg aaccttcaaa atacctgacc cactgacacc acgagtaaag
     4081 aaattgtgca atgtgcggtt gccagcttgt tgaattttca gttcatcacg taacgcataa
     4141 agtggtggta atcctgttaa accatcttgg gtgaaatatt tgaagtgcaa aatatcgcta
     4201 gacttcacac gtcttttttt atcaccaatc tgataagaca acgtaccatt atctaattga
     4261 gtaaccgtta cacttgagtt aggtaataag tgaatttctt ctaccttttc accgttgcgt
     4321 ttaatctctg caaagctatt accgtttagc aacatattga ccgccaaagc aaactttaaa
     4381 tgccaaccat ccatttctga attaggtttc tcgtttagta acttcaccag ttcattatca
     4441 gcttgtggca tattgttttt gaccaattga atcggacttg aagcaatatc actagcaata
     4501 attcgaacgg ctgcaaacac atcactattt cttaatgcac gaacgcttgt aaagctggtg
     4561 gtgtaatcat ccgattggat tgataccaca tgttgtagga aaggatctcc cgttgtattt
     4621 tgtctcgctt taaaaaatgc catcttttaa cctcccttct gttctgtatt tagcatgacc
     4681 gctaccccaa taagcactat gcccagcgct aacaagccat agtagacatt tgttagtaag
     4741 gtgatagcaa ccaacacaca caccaatcca agaagtaaaa gaacggtatg aatgtaatta
     4801 gaaagaaaat tcttcacttg tataaaattc attgtctgct ttcgctcctt ccgttgtggt
     4861 gaagtaatcc attgcaaaca cataggcatt gattaatgca gctattggat caattttgtt
     4921 actgttcttt gatttattaa tctgaatgcc gttgttatcc gtttttaaaa tagcgttgtt
     4981 cactgcatgg gtgagaatcg tatttttatt gtgaataacg ttgccttcat aaacttgttc
     5041 tctaaaagtt cgggtcggaa cgtttagagt aatcgttcct tgtcttactt ctaacattgg
     5101 gtagttggct ttttcagctt tactgataag cgaattagcg ttatacgggt cataacaaat
     5161 ccccatacat tccaaatcat tttcttgaat caaatcttga ataaactgaa atacttggtc
     5221 atagtccacg attccacttt ctaattgagt aatggaacac tcaccagctt tttctagttc
     5281 tcgataaggc aaaccgtcgc gcttttcttt gtcttgaagc ccatatttgg tggctacaaa
     5341 gctatgtgaa tcacaataaa gttcgccgtt atctagcggt acgatccatg aaacgctagt
     5401 taaatcatct gttttagata aatccactcc gatataaacg ggcttgcctg taatatcttg
     5461 tggttctact tcggttgcct gccagtcttc agcaatcata tagctgtcct cactcgcttg
     5521 tctccataaa ttgaagtttt tcaccaatac agaattaagg ttattttgtt tcaaagcaag
     5581 gttcacatca tcttgaatgg ttggaatcat tacttttttg atttcttcac tttcaaaaat
     5641 cggattggct ttgatccatt tctcttgatc gtgaatttct tcgggatcgt ccaattccca
     5701 tatcgctata aagtacctgt cggcttgttc ttcgcctttt agcacacgat ctaacaataa
     5761 gtattcctcg tacataggaa cgtttaaatc aagcccagcg gtactaataa cacacaataa
     5821 gccgttcttt tgttgggtca ttcctgactt aatgacgttg tacgttttac gagtttttgc
     5881 ttcgtgccac tcgtcaagaa ttgcggttgt tggtgcaaac ccatctagcg tgctggtttc
     5941 actagccagt gccatagcga acgaattaga gggcaagtgc tgaatcttag agttcataat
     6001 tttcagttgt ggtcttaaaa acttactaga cttgaccacg tttctaagtg aattagacag
     6061 catatcatag cccaatttag cttgtttcaa agcgttactt acaaacaata cttgccttgc
     6121 ttctgctggt tcttgttcca taatcaacgc attggcagcc atgccacttg cgatatacgt
     6181 tttcccattc ttacggctca tactggtaaa cgctcgattg aatcgcctgt aattcccttc
     6241 tttagtacgc cagccataaa gactgcctag aatgaatttt tgaaatccta acatcttgat
     6301 tgctttaccg tccgtagatg gtagcaactc aatgaattta atcgctttgg tggcttgttc
     6361 ttcatcgaac acataaggga agctatctga cttagaacgc tccaaatcgc ttatatgacg
     6421 ctcacacgct tggataattt tcttgggtgc aatcagctta cctgatagga ctttctcaat
     6481 gtaatcattc atgaattcat caactctttg aacgggtctt cgggttcatc atttttaacc
     6541 ttgttcaaag ctagttttga tcgtgattct aaggtcatac ctagtgaggt ggcttgtttt
     6601 ttcaaatcac tcatagcttg tgattgaacc cgaaccgctg gattggcttt ctttactccg
     6661 ttttcgcatg tgataaacgt acctgatttt cttatctcgg cttcggctgt tttcattcga
     6721 gcaaaggcta aacaataggc taccaatgaa ccataatctg cttcactcaa tggataatct
     6781 ttttttaatg ttggtacgat acgattccat tcacttctag cgctcgctgc catccagtca
     6841 gggggcgtga tatttattaa tggttgctgc ttgaacaatt cttctctagc gtccacacgg
     6901 attgcttttt cttcacttga tatattgcct tttgtatcgt gtaatatttt agggtgtccc
     6961 atgttgtcct cctttcagac aaaagaaaaa ggaacgtaag caattaagct cacattcctt
     7021 cgtttttcga tcagaatttt tctttatcta atttatctat ataaatgatt tttccgttct
     7081 gcatttgaat ggtcacttga ccaaaatgag gtaactcaat ggtgcgctgt ttccctgttt
     7141 tatcagtaat aacaattgta tttttcaata aatctcctac tttcattata tactttttca
     7201 cttgtgatta caagtgtaat cgttatttgt aattaccctt atgccttttc acaacggtta
     7261 tttgtaccaa aatgagtagg catcgattgt cagtaagttt cacactatgc ccccttaact
     7321 caaagggtac tcttttctcg tctttgtctt tcattggctg tcttggaatt atggtgtgca
     7381 tggcataaag aacgaaaatt agtttcatct aaccgtctat tccaatcatc ttttagttca
     7441 attttgtgat ctacaacatc agctttcctt atcaagcctt cttctaggca atcctcacat
     7501 actggatgat ttaaccgata caagtatgaa gcctttcgcc atgttctact ttgatagaat
     7561 tgaaaatatt taccttcgct ttgctttctt tcttcacgct taattgccgt ttgctttgct
     7621 ttatgcttcc cacaatactt ctgcctataa tcaatcaatg ttttacatcc agcatgatta
     7681 cattgttttt taactgccat agattaccaa ccaaagcgat ctcgttcgtc agaatcatct
     7741 tgttcccatt ttgatttgta ttcaatataa ggcgaaacta tcttcaagca cgttccgtct
     7801 ttaaaattaa ctttagtgat tttatcttcc tcaaaactaa taaagtctac atcttcttga
     7861 gtgtttgaat actcaatgtg tttctcacca tcgaagtatc taatactttc catatgcata
     7921 attattctac ctccaataaa ttagttatca attcatcatc tgttagtagc aaagccaaga
     7981 acttatcatg gatgtttaaa aacaaattat cctcattcga tgtaagctct cgttgtctcg
     8041 ctcgatcata taggttaagc agacaattaa attcatccat tagctcacct gtatcatcat
     8101 agttgccact atctaccaat gatcccacta ctagcgattg acaccacgct actgactcct
     8161 gcagccaatc aggttcttct tccattatct ttaatacttc tggatcaaat gtggaataat
     8221 cttctgttac caatcccaca ctaaatgcca gcgtgttcat tagaaaccga tccatttcat
     8281 ctgtatattg aaagttcggt gctttgtttg ttgaaataat attgagcatt tactttcctc
     8341 cttgattcgt aacacgtggt aacacctacg taacaggtac ccgttaccac tcaatcccaa
     8401 cggggacaag ggttctagcg ttttggtaac aggtaacggg taaaatccag taacattatt
     8461 ccccagcata ttagctaact atttcaaaag ttttaaggaa ataaggtgtt accccgttac
     8521 caaattgctg tatcccttgg ggcagtaagg gtaaactagt aacgggctag gtgttactga
     8581 cccgttacta cccgttactt tttgtacttt ccagctcgat ttttattttc ataggcattt
     8641 gacttattgt aaaatcctcg tcgtttattt ctttttggca gttgcttccg ttcccaacca
     8701 ggaatactgc taataatcaa ggcaatcttt ttagtttctg catctgatcg accattcaat
     8761 aaatcctttg cttgtttatc aaaaacagct tccaaaatat cagcggtgag tacgctatca
     8821 actaaataaa actcttgttg catagtagct ccattataga aatgctgtaa atttttctca
     8881 ttacatttac tgtcaggata gttctgataa taagaacgtc tcgcccacgc tggagcttct
     8941 tcccatttat acgggatttc catttccaaa tatttagtga ttgcttcttt aattggattc
     9001 tccatcttgg catcctcttg atagtctttt gcaatttcta agacttcttt atcttcatcg
     9061 ggactaaaat agattcgttg tcctttatca aaaagcacct ttgcttcagc taacacttga
     9121 agaaaatatt catcctttgt tttaaacgga ttcatctttg gcttattctt acaaggcaaa
     9181 ggataaaaac ggcggtttcc tgtatcatct ttcaaatact gcccatcatt cgacgttcca
     9241 ataaatacac attgccttgc ccaagctatg acattccgac cataaggagg tctaatttta
     9301 tcgatcttgg cactgatgaa gttttttatc tgttcaattt tagttttgtt cattgaagat
     9361 aattctccaa gttcaataat tacattgcct tgaagctgca tataatcatc tttcttttca
     9421 cctagcgaat ctaatgaatc ggtgaaaaaa tcatccgtgt aaagtaatgc tggaacggta
     9481 ctcttaccaa tcccttgcgg tccatccaaa actggaacga tctcaaactt tattcctggt
     9541 ttatagatac gtgcgactga tccgactatc caacgttttg ttacttctcg tgtgtaaagg
     9601 ttgtcgtcta cccctaaaag gtcaataaac agtgtttcca gtctaggctg ttgatcccat
     9661 ttaacttttt cgatacgttc ttttactggg ttgaaaacat tctttctagc cacatttact
     9721 actgctttgt gtattttgtt gtcatcaaaa actacattgt agttttcttc aatatatgcc
     9781 gttaaggcat cctcaaaact gtcttcccat tctccagcgg tacgattgat ccaaggagaa
     9841 tcttttaata ggtgaatgta tccgctaaat tcgttataag caattgttcc agctaaattg
     9901 ctatcattgg ttaaaatcaa ttctgcattc acaacactgt tacttttaat ctgatcgtct
     9961 ttattgcatc ttaatcgtga catccaggtt ttcaattcaa tgatattgtc ttcacgctcg
    10021 ctggcttcgg gaaagtctaa aatactatct aatttatgct tatgagccat gagctttccc
    10081 cctcaaatct tttttaatca tcgatcgaat aatttgattc acttctttat cttttagcgg
    10141 tggttcattg tacgcatttg ctgtataaat caattctgct aaagtttgat tatctacacc
    10201 gtgccatagt aaccaaccgc ataacttagt taaatgatcg tttctactac cttcgccagc
    10261 gccttgaaca atcatatcta atttttttgc tgtccctgtt tttgctacgg gtcggtattg
    10321 agtctttatt tcttgcggtt tttttagcag taggttcact agccaatcgg gagctggtgc
    10381 aatattattt agagatacgt tttcaatagg ttcatatgct ctcccaacac ttcttgaaat
    10441 aatcatagtt ggcgctattg gaactccttt agtgataata tcaatcccgc ttaaactttt
    10501 acctttatca tcacgcccga agatatcagc aaatgcacct gtttcttgtt ggataattac
    10561 accatcagga attttaaaga agaaatggat tcctttacct ggtgtgattt ccgtataagt
    10621 agaaggaaat ggatcataca ttgaagcaag ttttttataa ttctcaacgc cgtttcgtgt
    10681 ttcagaatgt tgatctaggt caactaccac catttgatga tcttcaagca ttaacccaat
    10741 atttctagtt gcatcttccg tccaccattc attaatttga ttagaatcgt tagttgcatc
    10801 attccaacca ctagagcctt ttattggaat tttagttcca ggagataagg gataaattga
    10861 ccatcccgac ttttgtaatt ccgttgctgc ttgataatta tttgccaata aacctctcct
    10921 cctttttcaa aatactggta taaatcattc agacacctcc atgagcttca actgctcaag
    10981 ttcgtatttc aacccatccc gaacaaattc agcacctttt aattgattct gatactttac
    11041 ccatgtatta aatgttttca cccttgcttc ttgcatatca gtaatgttta accatgcggt
    11101 taaaatctga ttttttagct cgttgatttc tcgacaaatt attttgtgtt ctgcatgttt
    11161 tttgagtaca tacaaaactg ttagtttttc attgaatgaa tttccaaagt aggttttccc
    11221 gatattattt tctagttcag cgatcccttg attaatttcc tctaattcaa ggctatcgag
    11281 ttggtttaat agttttgttt tgtacatcta cttatgccct ccagttctta attgatagtc
    11341 gtactcgtca taagcagtga agagatataa cgctaatcct gcaaagatag ctatttttgc
    11401 aattaatggt aataagccga aaattccgcc gattaaaatg cttcctataa ttaagtttcg
    11461 tttcataatg gttccctccg attttttaat atggtataat cggaacaaag aatatcgggt
    11521 tttatcccaa ttaagttgcc tttatcctgt ccgccaagac tgttatggat aaggcttttt
    11581 ctttgttctc gatcatgtta atgctcctaa gttgtctgca attcagcaga acgattataa
    11641 attttctcac tcactgaaaa ctgcaaccca tatttttctt taacagtcat taattctact
    11701 gtctcatcta aaataggttc acgatcaacc aacatttcag gagtcatatc tttctttttt
    11761 accattttgg aatgaccata aatagttgat acagctttat tggctatcac attcgcttta
    11821 atgtagtcta ctggttttgg ttcagtaata gcgtggctta atttagtcat tgcttctttt
    11881 tggtgttctt tgtctagcat gcggaatact tgaaagcctt caagtcctgt ggactggcgt
    11941 agttctttga tgatgtcgaa aatccagtct tgaaatgcct cggcttcttt tttacggctt
    12001 ttgaatgcca tgcggtaaat attttttttc gttgatgatg tttacatctt gtgttctgcc
    12061 caatgaatcg atgaccttac tagtagtaac cccatcttta ggcaaagagt gaatggctct
    12121 agtaacctgt ttaagaccta acgcttccgc aacatctttc gccactgccc accattcatc
    12181 attaatatcg acaaatctta taatgtgtcc gttccaaatt tcagttttca ttcaacgtcc
    12241 tccagttcaa gccctagcaa gctcgctaac aactcaactt gctgatacaa aatttcttga
    12301 tactcttcaa tagaaagtcg ttctttaaac tctgcttgta ctaaatcgtt caagccacgc
    12361 aatactccgc ttaccgttgg ttcttgtggt agcaattttt gatagtccat ttgttcgtac
    12421 aaacattcaa acgtttcttc tagcgctttg ccttccaagt ttgctaattc tgccgctgtg
    12481 tcttctgtaa gaattgttga taatactttt tcgattgctt tattttgtgt cgattccatt
    12541 attatttcct cctattaatc cctttgcccc cacggcttgc gtttattttt ggtattcttc
    12601 cataaagcga tcacattcat cttgtgaaat tcttacgact ccatcaacta taatcaactt
    12661 taaaccgtta ggaacatatt tctgcatcat agtattgtat gaaacgttca tatacttagc
    12721 agcttgtgcc ttgttcatat attttggaaa ctggtacttt ttttctaata atgaaagtaa
    12781 cgttccttga gtttgctcta cttgttgaac aactcgatcg tcaataattt taaaagctgg
    12841 atcatcaagc gtgagtttgt caatttttaa ttccatattt atcccccctc gttagcatac
    12901 atttctatac aaagatttta aaaaaatgca agaggctctt gaatacattt ctatacctct
    12961 tataaactca atataccatc ataccttttc atttgcaaga attttaacat acttttttga
    13021 acttttatgt ttcacacata tttaaatcgt gatatagtag agaaaatata tgaatggtgg
    13081 tgaaaatgtg gctagaaaaa aataccccga agcagtggag acaggacaaa gaattagact
    13141 ggctagaatt gaaaagggac tctcaatgga acaacttgga ggtaaattat ccccaccggc
    13201 cagtaaaggt gccgttagta attgggaaaa tggctataat cttcccaata acaccaggct
    13261 taaacaactt tcaaaggtat tagatgtatc cactacctat ctattaaacg gatcttatac
    13321 attaagagat atgcatatga tgcccgaaat taagcgaaat gtgcttgaaa agcaattgaa
    13381 aaaaactatt gaaaaaaata actctataat tgattctaat ctttctaatg ctatcaataa
    13441 catcgaagaa gataacctga ctgtctcaca gaagatttat ttaacaaacg caataaaata
    13501 tcttaaaaca ggatctcgaa ttgaatttcc tgacgggagt accccaattg cttatctcgc
    13561 agctcttcta aatacgcttt tacgatatga ctcattaatt aatgattcag aaaaaaatac
    13621 agatgagaaa aaagagtatc aagaatttta tgaaaatgat cttctaaaag agttcacagc
    13681 tcttgttact gagctaaata aacactattc aaaataataa taaactgcct cctccaaccg
    13741 cccccacggc ttgctacact atggagggaa aactattatg gcaacattca agcaatatga
    13801 aactaaaaaa ggtaaatttt ggctctatga agcctatctt ggaatgaaca aaatgactgg
    13861 caaacctgat aaggttcgta gacgaggtta caaaacaaaa aaagaagccc agcttgcctt
    13921 gtcacgcttg caagtggact acgataaaaa cggtattaaa aaagcgaaca acgaaacgtt
    13981 taaagaagtt tatgacttgt ggctagaaac atataaaacc actgtccgag aagccacctt
    14041 catgaaaact gaaatcaagt ttagaaagtg gattcttcca aaatatggaa atcttcgtgt
    14101 gaatgaagtc acggtaaaaa aagcccaaca aattgtaaat agctgggctg aaactactga
    14161 ccaatacaag gtacttcatt caacttctaa gcgtattttt agctacgcta tcaatcttgg
    14221 gattattgag actaatccac tagacaacgt attaatgcct aaaagaacca ccactaagca
    14281 taaagaaaag gtcaaagttt acagtaaaga acaactgatc accttgtttg attacctaaa
    14341 cagcaaacct gaaacttatc gaaacgactt tgataaaacg ttactacgct ttctctttta
    14401 tagcggggtt aggatcagtg aagcccttgc attgaattgg tcagacattg attttcaaga
    14461 aaatacggtc accatcaata aaacactaag ccaatccaaa aatggctata aaatcagtga
    14521 tcctaaaact gattgtagtg ctggggttct tccactagat gaaagaacaa tttctatatt
    14581 aaaaaaatgg cagattaatc agcggaaata tatgctgaca cttggtgtaa ctgatccgac
    14641 tatgattttt tgtggtatct ataaagaact aatcacacac cacgctattt atgcaagatt
    14701 gattactatt tgtgaaaaag ctatggttcc atttctcggt gtgcatgtag caagacacac
    14761 tcatgcttca atgctcttgg acgctggagc tactatggta gaagttcaaa ctagattacg
    14821 gcatacaaaa attagtcaga cgatcgattg ttacggtcac ttggcaaaag aaacgaaaga
    14881 aaagactgtt gaaaaattag tacaacactt aaatattgac tagatggcat acaatatggc
    14941 atacagtaaa aaataaaaaa aggagaaacc ctatcatatc aaggtttctc ctagctttat
    15001 agtctattct tcttcttccg ccatgaatgt attgaatact tcttcaatca tgtcccattc
    15061 tgcgtctgtt tcgatttgtt ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc
    15121 ataagcttgt aattctacat cttcatcttc tgaaacacca gcaggatata aaagaacata
    15181 gttacgtcca aattcttctt gtccgtcaac tgttagtagg atttcatata atgtttcatt
    15241 tccttggtca tccaccaatg tgatgtgttc gtgtccttca tggtcgtggg aatggttatg
    15301 ttctgtcata agattacctc ttttctttta ttattaaaat aattgcttac ctgagccgtc
    15361 taaataattt tgtaagatca tcacagctgc taatttatcg atgacttttt ttcgtttggc
    15421 tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg ttaatcgttc
    15481 atcttgataa tcaactggca aggagaatag ttctttgatc ttttctccgt atgacatgga
    15541 agcttctgcc cttggtccga tggaattgtt catattttta ggtaatccaa ctacaaaccg
    15601 gtctacttca tattgtgcta ctaattcctt caaccgatca aagccaaact cttcttctgc
    15661 ttcattgatc cgaatgatct ctactccttg agctgtccag ccaaaggggt cactgatagc
    15721 aacacctact gtcttagaac cgacatccaa gcccattact ctcataaatt cactccatga
    15781 tttgagaggt agtccttgac aattacttcc atgatctcat cgcgttcgtg acggcgaatc
    15841 aaatttcgag catcacgata acgaggaatg taggccgggt ctccagaaag caagtagccg
    15901 acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac aatcgctaat
    15961 gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt ttcatctgta
    16021 aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt ctacaacctt
    16081 attttactcg aagaaaggga aaactacaaa caaatattcc aaacttccga ataaattaag
    16141 aaacactatt tgtatgtttt tttccttttt tctgtagctt tatcaaaagt actcttttca
    16201 taaagtatac gctatatttc tttgaatgta tgtttttaca caattttttc ataatattca
    16261 taaaaaattc gaatagctgc tactaatttt ttgtttttgt tgcttgtcct gtctcataat
    16321 tgatcgtgta gccatcttga acattgtaga taaagacatt gaattcaatt tttttgtctt
    16381 caatgctttc tgcttccaat tgcactcccc tggctaccag ttcattcccc tcaaaatgag
    16441 gagtgacacg gtagcgtaca tgatgatttg tttctttgat atatgccgca atatcatttt
    16501 cgtgagcaag catgtatgga gcattcaacg aacgtgtccc tgtcatcaag tttttaatgt
    16561 tgttattttg accagtcagc tggaaaccaa ttaaatggct gcgattatat aaccattgcc
    16621 cgtcacttaa tttcttttgt ttccaacctg tcgggtcaat atacaaaggc tctctctttt
    16681 cagtagggaa caaatctttt ccaagcatag cattggcttg tcctactctg ttcaatttat
    16741 caatatttga atagctttcc catgttcctt tggaaaggct aagatcctct tttgtaaatt
    16801 ccggctgatt cccattgatt tctatttctt gatgttttcc atcatattct ggcacatccg
    16861 ctacttgaga agcttgtggt gtggaatcaa aaatagttgt aatctgctga aagatatctg
    16921 aatctttttg tgtggtggaa acaccgaatg cccctgcaat cacagcagcg acgatcccca
    16981 cgatcgcctt ggttgttttt ttgctcattt ctttactcct ttactaacag ctccctaaat
    17041 cttaacatat gttcccctat aaataaatac tagaaagaaa tagaaacagc aaaaaataaa
    17101 acctgtttta agatggctta aaaatacaaa aaagagacgg attcctcgtc tctaatcagt
    17161 caccactcta tctgtaaggt atttattatt attcaaaaat tttcttcata ctcaagacaa
    17221 tacactgatt tcacaaccgc ttggtaaacg gtgcgcaaaa gcttgcatct gcggtaataa
    17281 gtccatccaa gttaaaaaca taagaagttg tttttgcttg gctgttctta ttacttgttg
    17341 cagagcagct ttttcacaac ctattttaag cgggtgacgg gaatcgaacc cgcgacatca
    17401 gcttgggaag ctgggatttt accactaaac tacacccgca atacaaaaac agtatacgcc
    17461 tcttttattc cttcctcaag tttttttatt ctttacgctt ctggtatgtt ttgtagtaaa
    17521 ataaaactaa tcaatcaatt attggagaag atgctatgac gggaaaagaa ttagatctgt
    17581 tgctggacac ttgtttactc gctgggaaaa tcatgatgga aagcaatgcg gagatgtatc
    17641 gggtagaaga tacgatgagt cgaattgctt tagcttctgg aaatttccgt ttggtcagct
    17701 atgtcactca aaccggtctc tttattggtc ttgatcgtac ctcgaccatc cgaatggaac
    17761 aaattaccaa ccgttcgatt aatttagaaa aagtagtaaa agtaaatgat ctttcacgta
    17821 aatatgttgc ttcagagcta acattagaag aactttactg cgaactgcaa gcaatcgacc
    17881 gagaccgttc tttctttcct gtctggttgc aaatcgttag cgcggcagtg atcagtggaa
    17941 caattatggt gttatttggc ggaaagatga ccgatttacc tgtgacttta gtcattggag
    18001 gattgggata cgcagcttat ctatatagtt tgaaattttt tagaatcaaa tttttatcgg
    18061 aatttttatc ttctttattg attggcatag ccgctatcta cagcgtacgt tttggcttag
    18121 gaagcaatca ggatctaatc attatcggat gtgtgatgcc tttagttcct ggagttcaaa
    18181 ttacgaacgc tatccgtgat ttgctagctg gacattatgt ctcaggagtt tctcgcggaa
    18241 cagaagcgat gatgactgct acgatgatcg gttttgcgat tgcttttatt ttccagcttt
    18301 tttattagga aaggaacaca agtatgggga cgatatttat tcagttttct tttagttttt
    18361 tagcgactgc ggcatttgcc gttattacaa atgtacctag gcgttcattg atttgttgtg
    18421 gtctttctgg tgcttttggc tggatgatct actggatctg tgttcaaata ggcggatctg
    18481 ctgcttttgg ttcattgctt ggttctttag gagtagcatt catcagcgat cttttctcta
    18541 aacgtttgaa aatgcccgta acgattttca atattcccgg gatggttcct ctagtccctg
    18601 gtggtttagc ttatcaagcg gttcgaaatc tcgttactga atcctatcga gaagcggctc
    18661 attatgcggt ccaagcaatt atgattgctg gagcaatcgc tttaggtctt gtattatcag
    18721 aagtctttaa ccataacatc cgtaatttca aagtaaagcg tgacgcaatc atgatgaaac
    18781 gaaaaaaacg gctttttaaa taaacgaagt gtaacaaaga aaaggttgtg aaagagacgt
    18841 tcagccttga gcgatgacaa aatatctcac aaacattgcg acaagtaacc gcaggagcaa
    18901 taagaagtaa ttatgagtat taaaaaaagt tttgtaaaaa tagcttctca catttttaca
    18961 taaaattgac ttaatactga gaaactgact tttgaacacc ctctatctgt aaaaaagggg
    19021 ctgcgacatg atttttgtca cggcccctct tctttattca aattttttcc aaaacgttcg
    19081 ttgataataa acgatccata gagcggaaag tattagaact aaaccgatca caggaatatt
    19141 cactaaccaa aatggataaa acaaagccaa cattccgtat aagacgataa gaataatact
    19201 gatgatcaat gaacccatca tagttgcgac taaacccaaa cttcctgaac ctctgttaaa
    19261 taattggtta atattggtcc agttcagcag cagcaaccga taatctctag cgaaataacg
    19321 tagtgacaat aagtagcagc cgaataaaga accaaatagc aagctaggga taaaaaacaa
    19381 aggcagctga aaagacagtc cgcttaataa tgcgatccca ccagttaaaa aactctgcaa
    19441 tatccatccg aatctgaact tttcttttaa atattggttc atagagattg gcaaagaacg
    19501 gataaacaga aaattttctt gatccaaaga aataagattg ctgataaaag aagtctgatt
    19561 aactgttaag aaagccaatg cgatccctac caggaaaaca acaccgatta acttattatc
    19621 taaatcagtt aattttattt cgcctcctag ggcaaaagca agaataaaaa tgattggagt
    19681 taacaaggaa gaagaaagaa cttgcataat caaattaggt tcttttacta attgagcatt
    19741 gtaactaaat aaaagctgat gcacattttg gttcttttta tgggttcttt ttattttgaa
    19801 ctcactgttt gaatcagtca gttgctctgt aagctttggt actatcagct gttttacagc
    19861 aaggaaaaat cccagagccg tgatagctag tattccccaa cccaataaac cttgttgaga
    19921 aagtggctga ctggcagcat catagaatgg caataatatc gaaatcggat gccgatctgt
    19981 taactcattt tcaatagtcc ccgtttgatg attcatccac atgattccag caaatgcgat
    20041 cagcatcgag ctgccaagca agatactaga aactgttttt ctatgttttt taaacactgc
    20101 tgttcgagcc aaaccaaaaa caatcaaact agccagacaa aaaagaataa tcaaaaatag
    20161 agaaaacaaa aggattgaga taatgatagt aagcaaaatc cctagatcag ctcgccatcc
    20221 ggttaaaata aacatgacta gaagcggaaa aacaaaagga atgatggtca aagcaactac
    20281 caaaatcttt gctgaaaaaa cctgttcttg tccaaaaggc agaggcaaaa atacttgcag
    20341 gtcatttcct tcaaaaaaga tattataaat gactgatata ctttgagtta aacctaacat
    20401 accaaaaagt gccacgtaat aagtaaagaa acctggcaat ttaacaaagt tcatagcaaa
    20461 catagcaaat ccgtaaatca gtaaaaaaat cagccctgaa aaaagatttt gagacaaaag
    20521 atagatagtt aatcgctttc ccttttttcc tttctctctt gctttattcg tgagctgtgg
    20581 attaacatat aaaagattaa ctcgaattaa ttctaataat tgtcgcttat acatacggtc
    20641 catctcctgt cgcttgcctt ccagccattt tcaaataaat cttttctagc gtttcatcag
    20701 gtgagccatt caataattca ctaactgccc cctgataaat caattcacct ttcttcaaaa
    20761 tagccagttt atcgcataac tgttgtgcgg tatccaatac atgtgtagaa aaaatgactg
    20821 tttttccttt tgcggcatga gccttcatca tttctttcaa atcaaatgct gcttgaggat
    20881 caagtccttg caaaggttca tccaataccc aaatatctgg atctggcagc aacgtgccga
    20941 tcaaaatcgt tttttgacgc attccatgtg aaaaacttgc gattgtttca ttttgatgac
    21001 tatacatatc aaaaagcgct gtcaattctg ctaaacgctt ttcttttttt tgtgtgtcta
    21061 attcataggc agctgaaatc aagtcccaat attctccagc cgtcaattgt aaaaaaatat
    21121 ctggggaatc aggcacataa ccgatttttt gtttgatact caatcgattt tccgtcaatt
    21181 tcattccatc tactaaaatc gttcccgatg atggttcaat aatactaact aaacttttaa
    21241 tcgtagttga ttttccggca ccattatgtc ctaaaaatcc aaaaatttcc ccttgtctta
    21301 tcgagagaga caagtctttt aatgcttgtt ttttcccgta acttttactt acattgatga
    21361 attcaatcat ttctgtactc cttttgtttg ttattacttt ttattgtacc cttcgttatt
    21421 ggtggagtaa atgtcaaaaa gagtgcataa caaaaaagga tagaaacgac taggctgcta
    21481 cttgggttgt tctcttctac aggaaaacac tcttctaaca ggtaagatat gagtctttgt
    21541 tttctttaaa atgattcatt ttctatcttt tcttgcataa aattctttag tttatcaata
    21601 cttctctttc ccatctctag ttgttctcca tttgcaaatg ttactatttc gtttactctg
    21661 ctaatagatg taatgttttc agtattaatg atataagctt ttaaatcttt acataaatac
    21721 tcatattcga gtgatttttt atatttttta attgtgccgt ttacgagaat ctcttcatct
    21781 ttcaatacta ggcctatttt atttttataa cctggcatgc tcattagata aaggatttca
    21841 tcgtaatgga tatagtgatc gctattacca taacggacag ttgtccacct ttttttcgta
    21901 gcatgttgaa caggatagtt ttctttttct ttcaataagt aactttggat gcttttttta
    21961 tttttttcat aagtgaattc ttttatcaaa taaccactag gcgtaatctt tcgattaata
    22021 acagttattg ctttattcgg atgagacgtt agataaacaa ttttacactt ttcattcttt
    22081 tctctaagca tttcgcctag ttcgataccg ctataatagg cgttcaaatc gatgtctagg
    22141 aaaaaaatat ctgaggaata gatttcatta tttttaatga attcaacaaa ttgtataacg
    22201 ttcaatccct gaacgatctc aaatttccaa ggacttaata aaattctgga ttcttccaaa
    22261 atttctacta gcattttttc aaaaaccaaa ctatcatcca aaataaatat acgcgttacc
    22321 ataaaaagta cctccactcg atattttact atcaaaatca tttcatacaa cttttcaaca
    22381 tacatgttag gaataaattg taattctctt cacaatcttt tccaacacct ttgaaaccga
    22441 tatcaaatac tttcaggatg ctgcttctaa aataaatatc aaacaaatga atacatcatg
    22501 caaaaaaagc cagacaaccg acgtccttgc gtgtcagctg tctgagctat gtttatttat
    22561 tttgttcttt taaaaagaac gatacacata ctgatttttc ggagcagaga ctttctcagc
    22621 gtttgtaaca actacagatg ggatttcacg cttgaatggt tgataatagt ctgattggat
    22681 ggttccttct attttatacc attcatcatt tttaaccgtt actccttccg gcatatgcgt
    22741 caacaaacca aagactcctg aatctgccac acaatggata atgccgaatc ggaacaagaa
    22801 gatatctgta ttgctatcgt tcggtgtttg gtaaacaaat ccttcatagc tgattttttt
    22861 gccaatgaat tcgctagggt aattataaat tagctccata acttctaaat agttttcatc
    22921 tgtgatcttg atagtttgct tatccccata cttttctttc aactcattca tttggtctaa
    22981 gtagtctgat ttgttgaaat aaatactggt atccggcttt aagtattgtg tctgcatctc
    23041 cggatcccct actgattctt tacttactgg gaaattaaat cctttggctt ctacgatcgt
    23101 agtgtcgaga ctaactgttg gaaacaacgt ccccacgatt actggcaaag ctagcagtac
    23161 ataagcgatt ccacgttgat aaggttttga caacccatgg tcatgatcgt gctcgtgtgc
    23221 cttttcttct gcttttccgt ttttgaccca caaatacagc tgaactaaag ccaaaagagc
    23281 agataaaatc attgaaagaa tagctaagta gcgataatgg acattgatat attgatcgag
    23341 tttgccagaa acttgcaagt acatcatcaa ttcgaaatac ccagataaaa tcaaaaaccg
    23401 cagcatattt tccctcctaa ataaataatg tgaatccaat aacgctaagg gcaatcagtc
    23461 cgatcagcga taaaataaag cgtcctgtaa aatatcgttt catcatcagt agatttttga
    23521 tatcgaccat tgggccaaag accaaaaagg cagctacagg tgctgtgccg aacagactta
    23581 acaaagaaga tcctataaac gcatctgctt ctgagcaaag agacatcgta aaggccaata
    23641 acagcatgat gataatggct aaaatctttg ttgagccgag cgttagcata attctagttg
    23701 gtaaataagt ctgcatcgca gctgcgatta atccgccaat gatcaaataa cgacctgtat
    23761 caaaaaattc gtcgattgaa tgtgtcaaca catgcccagt ttgatggatc agctgatttt
    23821 ttggttcatt cttctcactt tgttcttctt catggacatg atgatggtga ttttctgcta
    23881 ctttagacgt gattttttct ttcaatacag cgtctttttg aaaataggca agccagacac
    23941 caatcacaag ggcaacaaaa aagctgccta tcacccgcca gcttgccatc tgccaagaat
    24001 tgccaaatgc gataaaagtg gaaaaaatca cgattggatt gatgatcgga gcagtcagca
    24061 taaaagcaaa cgctgtgtga actggtacgc cttttttaac aaattgatga acgatcggta
    24121 cgatgccgca ttcacatgaa ggaaagaaaa atcctaagat cgaaccagta aaaatagaga
    24181 agatacgatt ttcaggaagc catctcttca cacgttctgg ggtcaaaaat acttgtaagg
    24241 cgcctgagat aagacagcct aataatacga aaggtaatgc ttcaataacg atcgataaga
    24301 aaatcgtact catctgcaaa accgaatttg gaataaaaga aaacatgagt ttcctccttt
    24361 ttatttctag ttcattcgct ttgcaaatat acgcttttat tcaaaaaaaa caagttgctc
    24421 tgtaaatttt tacacaactc ttatttttta ccaaagcact tcaattgact ttttctgtta
    24481 ttcccattaa attaaggtct catacatatc acttctatca taaaagggag aataaaaatg
    24541 aaacaaacca ctaacttgac tgaagttcaa gacatactgc aacagtcatc cgttgccgtc
    24601 atttatcttt cgatgcctaa ttgcagtgtt tgtcacgctg ttcgtccacg actagaggaa
    24661 cttctcacac attatgatat tccggcactt catttggatg catttgaaac accagaagta
    24721 gctagtaaat ttgaagtgct gactgcgcca gttgtcctga tttttcatca aggaaaagaa
    24781 gtctttcggc aagcacggtt catcgacttt aaaaaaatcc gttatctact agatgaactg
    24841 acagcagaag atgattccct ttcttatgaa gaaatcttcc gaacaaaata atcgttgtcc
    24901 aaacagaaaa aagcgattga acaagtgaaa gttttgcctt catttgttca atcgcttttt
    24961 atttttattc tgctgtattt tcggaatgcg catttgcgtc agaatgcaag aaatagatca
    25021 aggtttgcaa ttcattcgtc aaatcaacat tttggatcaa tacatctgac ggagcattca
    25081 atcgagcagc ggtaaagttc aagattcctt tgattcctgc ttccgttaac tgattgacta
    25141 cttcttgtgc tctttcagcg ggtatcgtta aaattgctac ttcgatttgt tggatcttga
    25201 tttgttctga catatcttcc attggataaa cggggatacc gtctacgatg cgcccaacga
    25261 tttcctcatt cacatcaaaa gcacaactga tacgtatgct attactttga tggaatttgt
    25321 attttagtaa agcacttccc aagttcccta caccgatcag cgcaacattt gtcaattgat
    25381 cgtcgtttaa tgtctttgca aaaaagtgca taagatcttc tacatcataa ccatacccac
    25441 gttttcctaa ttcgccaaaa taagaaaaat ctcgacggat cgttgcacta tctacttgaa
    25501 cggcttcact taattcagtt gaagacactt ttttctttcc agcattattt aaaatcctta
    25561 aatagcgata atacaaaggc agtcttttag ctgtcgcctt tggaataata tgatctttca
    25621 cgaaatgacc tccacgtatt gtctaattac atctttgatt tctccatcat agcagtattt
    25681 ataggaaaaa atcaattcca ttgctcagat attgtgaaat tttattcttt attcatttat
    25741 ttatcatttc tgcaaatctc gcagtataat ggaatttatg gtagactact aattgaaaaa
    25801 tagtttttta tttgaggaga attcacaaag tagaaaagag gattccatga tattattaca
    25861 agccaatcag attgctcgcc attttggtgc agaagtctta tttgaaaaca tacatttaga
    25921 aatcagtaca ggcgctcgtg tcgctttagt tggcagaaat ggcgctggaa aatcgacttt
    25981 attaaagatc attgctggaa ttgaagcacc tgatgaagga aagatcgcta aaaataaaac
    26041 agcgactctc ggatacctcg ctcaggacac aggacttgat tccaatgaaa cagtttggaa
    26101 cgagatgctg aaagcttttg aacaagttag acaaatggaa gagcggatgc gcgagctaga
    26161 gattttcatt agcgaaggta cgccagacac acctgcttat agttcttatt taaaagaata
    26221 cgaccggctg caacacgatt tttcagatcg aaacggctat ggttatgaaa atgaaattcg
    26281 ttccgtattg catgggttta aattcgattc ttcattttat gatcagaaaa tcgatacttt
    26341 atcaggcgga cagcgcacac gtttagcttt agctcgcatg cttttgcaac accctgacat
    26401 tttgattcta gatgaaccaa cgaaccattt agatatcgag acactttcct ggcttgagaa
    26461 ttatctgcaa agctatactg gtgcattatt gattgtttcc catgaccgtt attttttaga
    26521 taaagtagtc aatgaagtct atgaattaag cagaagaaaa atgcgccatt acaaaggtaa
    26581 ctattcgaaa tatctagatt tgaaagcaga acagttagca agtgaatgga aggcttatga
    26641 aaagcagcaa acagaaatcc ataaattaga agacttcgtt gctcggaacc ttgttcgcgc
    26701 ctctaccaca aaacgagcgc aaagccgcag aaagacatta gaaaaaatgg accggctgga
    26761 tcgtcctcaa ggggatgaaa aacaagcaaa ctttctattc agtatagaaa agccttctgg
    26821 aaatgtagtc ttgcaaatcg aagatgccgc tatcggatat gataatgtca ccttatctga
    26881 accaatcaat ctagatatcc gtcgtcaaga agcgattgct ctagtaggtc cgaatggtat
    26941 cgggaaatcg acgttgctga aatcaatcat tcaccagatc ccttttatcc gtggaaaaga
    27001 aacgctaggg acaaatgtca ccatcggcta ttacgatcaa ggtcaagctg atctgcatac
    27061 aaacaagacg atcctagcag aattgtggga tgagcatcct accactccag aaaaagagat
    27121 ccgaagtgct ttaggtgctt tcttattttc tggcgaagat gtagaaaaac caatccctct
    27181 gctaagtggc ggtgaaaaag cacgggttgc tttagccaag ttagcgatga acaaagaaaa
    27241 ttttttgatt ttggatgaac caacaaacca tttagatatt gacaacaaag aagtattaga
    27301 aaatgcattg atcgattatg acggcacact gctttttgtt tcccatgacc gatatttcat
    27361 caatcggatc gcgacaaaag tcgtcgaact ctctgaaaat ggcagcaaag tctatctagg
    27421 agactatgat tattatttag agaaaaagca ggaagaagaa gaaatcgccg aattgttggc
    27481 acaagatgag ccagaatctg ctcctgctcc cacgaacaaa tctgattatt accaaagcaa
    27541 agaacagcaa aagcttatcc gtagccttca acgaaaaatt actcaggttg aagaagaaat
    27601 ggcgcggatc gatgaatgga tcgatcagtt ggaacaagaa atggtcgcgc cagaaaacct
    27661 ggaagatcac gtaaaactca atgagctgaa ccaagattta gaagctgcta gacaagatca
    27721 agaaacaaaa ttgacggaat gggaagaact aagcttggaa ttagaagaat atgaaaatta
    27781 acgaaaaaac caaaacagaa accattcatg ctgttttggt ttttcttttt ttattttatc
    27841 aaacaaaaat tccatattta cctttttcac caataagaag accaattact agtcattctc
    27901 actaaagctt ctaaataata gtaatcaccc caaatacaag gtgtatttac cccattattt
    27961 ttgggcttat tataaacaga ctgtgttaaa aagccatctt cttcttccgt tgtagcatat
    28021 ctttctttca attgtcgcat aattttccaa acagcagact ggtataagtt cttttctgtt
    28081 ttgtctaata gacctgattc tattaattct aataatccac aaaccatgat caccatacta
    28141 gatgtatctt tttcttctct gctagaatca tcaaagatca aatcccaata acaaatggta
    28201 tcttctggca accgattcat aaaataattg gctaatattt tgcttaaatc aaaatatttt
    28261 tgttctttca aataacgata acttaatgca aaaccgtaaa tcccccatgc ttggcctcta
    28321 gcccaacagg aattatcact ataaccttga tgcgtacttc catatcttgg ttttccatct
    28381 ttgacatcca tataaaatgt atgataagtt gaaccatctt ctcttactaa ataatctgct
    28441 gcattttgaa tatgagcctg agcagctttt ttatattttt gatttccagt ttcttcactc
    28501 gcccaataca ataatggaag attcatgcaa caatccatga tcattctacc ttgttgtgaa
    28561 ggatcactag gatctcccca agcttgtata actcctgcct tctcccaaaa acgctgaagt
    28621 aatgtttctg cagcatcaat tgaagcttcc ttcatttttc gatttcccgt tattttataa
    28681 tctgctacgg ttgataaaga atacaaaaaa ccaagatcgt gatgattagt gataatttga
    28741 cagtcaatcc tgtggataaa atctatatct gctttttcag ctgtttgttg aaataaagga
    28801 tcacccgtct tctcaaataa caaccaatta attcctgtcc aaaatccttc tgtccaacca
    28861 atattgtctc ttaatggata acgtcctttt ataggacact cgcttgggaa ttgatactga
    28921 ctgttactga tacgtttgat taacctctcc gtgtgtctgc gacaacgctc gatctcatta
    28981 ttccattctt tttccattaa ttctttataa cattcattta tccatttttc tggatgtatt
    29041 atctcttcaa acatcacttt atcaagcatt tccccaccag cctttagcat aattttagtc
    29101 tttttttatt gtttttattt tggatagtta gcccggttgt cccatcaaaa tcaattttgg
    29161 gacgattgtt ccatacttct aaactataat cccgatcttg atgagcaacc actcctgttc
    29221 cgagccaatg ggttcctttt ccaaatgtac cctctaatcc aggaataaaa gtgttttccc
    29281 atgtcatcaa gtttgtattg ggcaaaccca taatagctgt ggattttcgt ttaatagtat
    29341 cgtcacttaa acagataata cctgaaaagc cagcttcact caccctatag ttttccttgt
    29401 cttcttctat gattattcct tctttctcag gagaacattc aatagcaaac cctgtctcat
    29461 atagaacata ttctgtatct aattctactt tgtgtacgcg aatctgccag ccttcaaaag
    29521 gaataagcca agttctgatt tttgcctgta aagtaggttc ccatgtagag gcaagtacct
    29581 ctttcttaca tacaatgtct cgtacattat ttcgaacgat gaactgtcca taggttttga
    29641 tgctctcatt cttaaaactg gtcgtgatat atgtgtccgc tcgctgaatc cctagcattg
    29701 aatccattgc catttctgct ttcaattgat tcgctcgcgg tatcgaaaaa ccaaattgac
    29761 tagaataagc aaattttaaa tatttttcat tggtcaatgt atggaaattt ggccctaatt
    29821 gtcccgcatt caaaaaaaat gtatgtccat tatcatgttg tatgagcaaa ttggcttctg
    29881 aaagaagttt agttccttca cgaataggca taggcatttc tttagccgtc caatactcat
    29941 ggtcttcagg tagcgccaac aataaaaaaa tcttattcag ccataatgga gataacgtac
    30001 tattataggg ttcagtcaat gtcaattgag ggtaggtata accaatattc aggatacctt
    30061 tttcatcaaa tatttctttt tgcatccacc atcttatatt ccgattgact aaccccttga
    30121 tttcacctaa tttaaaaggc aaaagatcgg cccacaacat agctgaccaa aagcttgaaa
    30181 ctgcaaaacg ataaatcatg cttcgaccaa aaggcacatt tgcaccatct tccgcaaaaa
    30241 aatgaatata gtctctagaa aaatcaatag ctcggttctt atatatctgg ctaatgggct
    30301 tttctggttc tagtacgcta taaatcaaac cataataatg aaatgcaaaa ggattataat
    30361 aatcttggcg acctcttgaa ctgtctcgat accagccatt ttgaagataa caattttcta
    30421 tattatcaaa tgcttctttc agtgctgatt ctttaactgg ataaccaaat ttttggataa
    30481 ttgttccgac aattatctta aaaaattgcc aattaccatc tgcacattca tattcaaaaa
    30541 tttgcgagaa ccaatgaata atctggcttt tttctcctgt atctaatttt ttccataata
    30601 attgttcatg atgatataac gctaataaca ttgcgggcat ttctaccata cgctggtctc
    30661 tttcatgtat ttctccccaa taatcgggat gggaaggatc tgttccagct tttattcctg
    30721 atagaattaa tttcaaccat cgttcatcta attggtcaat tgcgggcccc gctccccata
    30781 aaacccgaga gaatccttcc attcctgcaa ttttatttcc atatcctacc ccttgatgta
    30841 tataatcaat ttgtgcgcca cttgctcgat aaaacggctg gagtggttga tttatctttt
    30901 taaataagtc aaagtaatcc tgtctggtcc ttaatagtgg tactggatgt ttcattgtat
    30961 tttctcctct ttttactacc aaatagctaa ttccgactgt tctaatcgaa gtaagccttc
    31021 aataaaaaaa taatcagaat agatcagtgg cacattataa gtcagttctc tatggtatgc
    31081 ttctgctccg cctccaatga tcccatcttc atccatattc caatttgcat agtgcttttc
    31141 tgtcttttgg agtatattga tagcagcttc atgatacatt tttgatcgta cagaggaaac
    31201 atatcctgct aattccagaa gaccgcatgc agcgcatact ccagcactgg tatcaatatt
    31261 cgaatctttt acagcaaaat caatgagagg aatataacca gttttttcga ttttctgaat
    31321 aaaatttact gctatctttt ctgctatagc tagatagtac ggattttttg tgtaacgata
    31381 acttaacgcg aatccatata aagcccatgc atttcctctg ctccaacaag aattctcatt
    31441 gtatccttgc ccgccaagta accgaatata tttccctgat tctgcatcaa attctgcgat
    31501 atgcccggtt gatccatctt tcctcactag atacttagct gttgtatctg catgctgccg
    31561 agcaatttta gagaacctcg gatcaccagt ttccctcgaa gcccaataca gtaatggtaa
    31621 attcatcata ctatcaataa tcatccaacc aggtttatgg tcattccatg ctactaaata
    31681 gttccctgaa atattatagc gtccagcaag taccgtagct gcatgtaacc ctagttgtcg
    31741 actatgtttg ttttgagact gttgataatg tgcaatagcc gatggtaaga ataaaaaacc
    31801 tacatcatga tgaacgtctg aaaaatggta cagggcagat tctaataatt gttcttgttg
    31861 tattgctgcc tctttgaact tttctcgttt tgtcttgtga aagagctgcc ataaaatacc
    31921 actccaaaaa ccattggtcc accagtcgat tcctctgtcc tttattacgt ctgtatattt
    31981 tccgttgtaa gaaatatatg gaattttatt ccccattctg tctaattccg catctatctt
    32041 ttcagaagct acattcaaaa tttttcttga ccattccttc gtctgttcat tcatggatat
    32101 cccgccattc ttttaatttt tatgaatgtg gagttgctcc tagaacgaac tagatggtta
    32161 acattcgtta ttttttttac ttatttgcag ctccaatgtc attctcctta aatttagact
    32221 gcgcccacac ataaatcaag accattggga tcactgaagt tgctaaaatt agcataattg
    32281 cgccataatt aattggctca cctgtactag aaaccgtcat atttttgata attaagggaa
    32341 ccgtatattt atctttatct gaaagcatga ctaatggaaa tagatattga ttccaacttc
    32401 ccataaagat aagtaaacca ctagtaataa tcgtaggtga taaaatcggt acagcgattt
    32461 tcgtaaaaat cacccactca ttggcaccat cgattctggc agcctccatc agtgctgtag
    32521 gaaattgact gctatattgt cgcatcataa acactgaagt tgtactggca atcgaaggga
    32581 tgatcacacc tgcataagta ttcgataatc ctaaacgact cataatgtaa aataaaggaa
    32641 tcaatgtggt aaaaaaaggc accatcctag atagcataac tgtattgaac aacagtttat
    32701 tccccataaa acgatacttt gctaatgcat aacccgccat tgtagaactg gctgtagcta
    32761 aaactgtact gattacagca ataacaatcg aattccaaat aatcaaggga taattatatc
    32821 tcgccatgat ggcttgccag ttttttaata gcatatcccc aaacttgaaa ttgattccgc
    32881 cacttaaaat ttcttgatta ctttgcgttg aagctacaat catatataaa tatggcatca
    32941 aaaatattaa ggcaccaaac acaataatga cgtacgtaaa aattctgctt tgtatctttt
    33001 gtttagtcat ttttatcacc tccgaattta aattgaatag ccgataatat aacagataca
    33061 aacaccatcg tccaggcaat agcagaggct tttccaaaat caaccatttc aaaacttgtt
    33121 ttatataaat tgaccctacg accaaagctg aattttctgg tccattggaa gtcccaaaga
    33181 atatatttgg gatattgaaa ttacccaagc cattgatagt ggctaaaact gtggccatta
    33241 aaatgattgg ctttagcatg gggatcgtta ataaaaagaa ttgccgaaat ttcgatgctc
    33301 catctatttc agcactttcg tatatctctt tagaaatccc ttgaagacca gctaaaaata
    33361 aaatagtgtt atatcctaca ctaagccaaa tcatcgtgat gatcattgat attcgtatcc
    33421 aaaaaggatt tgttaaccac tgtacaccgt taattcctag cgcattcaaa aatccattga
    33481 ataacccagt cggattgaaa aaagtcatga atacggaagc tacagccacc gttgatgtaa
    33541 tggttggaat ataatagaca gttctaaaaa atccttttcc ttttaactgt gctgaattca
    33601 ataaaacagc aaagtaaata gctaatagca tcgttattgg aattgatcct gccatgataa
    33661 tcaaaacatt cgtgtaagat ttaataaaca atggatctcg gaagatagct agataattgt
    33721 caaatccaac aaattcaaat gagtagccaa ttttcataaa actaaaagca aacgagataa
    33781 tgatgggaat caaaatcgtc acaataaaga aaataacaaa aggtgtgacc aatccataag
    33841 cacttttttt atgagacgta tctgttgctt ttttcttgct gttctttatt gtcttgcttg
    33901 gtaacgaaga ttgcatcatc gttaagtcct cctaatattt tttaatcacc agttaatttt
    33961 acgccgtact tatgagcaaa attttctgct tcttttagat atgaattttc aaaatcacct
    34021 gtttgccaat agttatatgc agcggtagtc aaataagacg tagcatctga ataagtggct
    34081 ggtaaaacag tatttgatgt attttcattg attttattca atagttcata gtatttttgt
    34141 cctccttagt agtcaaactt tttctcagct gcttctgttt gataggccaa tgagttagat
    34201 gtagccacgc ccagctccag tgcgttggct aagcattctt catctgtcag cataaatgta
    34261 agaaattgtt gtgccacttg tggatttttg gcatctttag ggacataaaa acttgatcct
    34321 cctgatactg caccttttcc tggattttct tttgaaaaag gaatcagtgg agccatgcgc
    34381 catttgtcag atgcatcagg aaaattcaaa gacatattcg tagcatacca gccgccagca
    34441 acaaacattg cagattcttg aaatgctttc tcagcatctt gtgcaccgta gaaatgtaca
    34501 atatctgagt cgatcatttc tttgattaac tttgcagcat gtttcgcttc tttagtattc
    34561 agacggatat ttccttcttc atcaagcaaa gattgattct gctgggctag catgttgata
    34621 aacaattctt ggtccccaga ttctggcaag gcaattccaa aactaccagt tttttctttt
    34681 aatgcttttg ccacctggat atattcttcc caagaactga tttcttcaaa atctacacct
    34741 atttcagcaa atttttttgg ttgataataa caaagtgctg gggtaaaatc actagcccaa
    34801 ggaataatcg tttcattact cgtttgttga cgcaaaatat tcaatttttg atcataaaac
    34861 tgatcgccat atttgtcata aaatccatat tcatcagcac tataaaaagc atcttgaaat
    34921 ttttccagca cacctgctgc tgaagtgtct gccatggaga taatatccgg catatcttcg
    34981 tgtgttacca attttggggt gatcatttgt actgttgctg ttcccgaagc tacattcaca
    35041 atttttaagt caatatttgc tccagttttg cggttataga tttttgcagc attttcaaca
    35101 tagtttgtca gtttgccgtt tgcgacatat acttctaatg tagtggcttt ttttatcatt
    35161 ggatctgcga tgtttgctgt tacttcttcg ttagtttttc cacatgcact taagctgaat
    35221 aatagggtaa tgtttagcaa agctatcacc aatttgtatc tttttttcat gtctatccct
    35281 tctttctttt caagttctta tataaaacg
//
LOCUS       DADQCX010000020        34604 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.020, whole genome shotgun sequence.
ACCESSION   DADQCX010000020 DADQCX010000000
VERSION     DADQCX010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.020"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(208..2100)
                     /locus_tag="J8R83_000917"
     CDS             complement(208..2100)
                     /locus_tag="J8R83_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574061.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2097..3824)
                     /locus_tag="J8R83_000918"
     CDS             complement(2097..3824)
                     /locus_tag="J8R83_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574062.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3840..4490)
                     /locus_tag="J8R83_000919"
     CDS             complement(3840..4490)
                     /locus_tag="J8R83_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574063.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4694..4990
                     /locus_tag="J8R83_000920"
     CDS             4694..4990
                     /locus_tag="J8R83_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAZ9574064.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5162..5782
                     /locus_tag="J8R83_000921"
     CDS             5162..5782
                     /locus_tag="J8R83_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAZ9574065.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5874..7040)
                     /locus_tag="J8R83_000922"
     CDS             complement(5874..7040)
                     /locus_tag="J8R83_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9574066.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7052..7405)
                     /locus_tag="J8R83_000923"
     CDS             complement(7052..7405)
                     /locus_tag="J8R83_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAZ9574067.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7533..8555
                     /locus_tag="J8R83_000924"
     CDS             7533..8555
                     /locus_tag="J8R83_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAZ9574068.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(8994..9428)
                     /locus_tag="J8R83_000925"
     CDS             complement(8994..9428)
                     /locus_tag="J8R83_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574069.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9538..11397)
                     /locus_tag="J8R83_000926"
     CDS             complement(9538..11397)
                     /locus_tag="J8R83_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9574070.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11515..12675)
                     /locus_tag="J8R83_000927"
     CDS             complement(11515..12675)
                     /locus_tag="J8R83_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAZ9574071.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(12982..14406)
                     /gene="araA"
                     /locus_tag="J8R83_000928"
     CDS             complement(12982..14406)
                     /gene="araA"
                     /locus_tag="J8R83_000928"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAZ9574072.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14422..15120)
                     /locus_tag="J8R83_000929"
     CDS             complement(14422..15120)
                     /locus_tag="J8R83_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAZ9574073.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15077..16738)
                     /locus_tag="J8R83_000930"
     CDS             complement(15077..16738)
                     /locus_tag="J8R83_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAZ9574074.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            16956..18356
                     /locus_tag="J8R83_000931"
     CDS             16956..18356
                     /locus_tag="J8R83_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAZ9574075.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18608..19687)
                     /locus_tag="J8R83_000932"
     CDS             complement(18608..19687)
                     /locus_tag="J8R83_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9574076.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19773..20732)
                     /locus_tag="J8R83_000933"
     CDS             complement(19773..20732)
                     /locus_tag="J8R83_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAZ9574077.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20744..22267)
                     /locus_tag="J8R83_000934"
     CDS             complement(20744..22267)
                     /locus_tag="J8R83_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAZ9574078.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22277..22840)
                     /locus_tag="J8R83_000935"
     CDS             complement(22277..22840)
                     /locus_tag="J8R83_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAZ9574079.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22846..23709)
                     /locus_tag="J8R83_000936"
     CDS             complement(22846..23709)
                     /locus_tag="J8R83_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574080.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23723..24619)
                     /locus_tag="J8R83_000937"
     CDS             complement(23723..24619)
                     /locus_tag="J8R83_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574081.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24794..26065)
                     /locus_tag="J8R83_000938"
     CDS             complement(24794..26065)
                     /locus_tag="J8R83_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574082.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDLVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26055..27572)
                     /locus_tag="J8R83_000939"
     CDS             complement(26055..27572)
                     /locus_tag="J8R83_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAZ9574083.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27770..28660
                     /locus_tag="J8R83_000940"
     CDS             27770..28660
                     /locus_tag="J8R83_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAZ9574084.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28733..29557)
                     /gene="nadE"
                     /locus_tag="J8R83_000941"
     CDS             complement(28733..29557)
                     /gene="nadE"
                     /locus_tag="J8R83_000941"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAZ9574085.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29569..31041)
                     /locus_tag="J8R83_000942"
     CDS             complement(29569..31041)
                     /locus_tag="J8R83_000942"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAZ9574086.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31678..32040)
                     /locus_tag="J8R83_000943"
     CDS             complement(31678..32040)
                     /locus_tag="J8R83_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAZ9574087.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32263..33015
                     /locus_tag="J8R83_000944"
     CDS             32263..33015
                     /locus_tag="J8R83_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9574088.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33155..34078)
                     /locus_tag="J8R83_000945"
     CDS             complement(33155..34078)
                     /locus_tag="J8R83_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9574089.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34093..34365)
                     /locus_tag="J8R83_000946"
     CDS             complement(34093..34365)
                     /locus_tag="J8R83_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574090.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10228 a         7199 c         5945 g        11232 t
ORIGIN      
        1 ttttgaacac cgtttaagga agaggttgta aaatcagcgg tttgacctga gtattagaga
       61 tacaaaacgg aaaaatagct tctcatattt tgccgttttt tgagctaata ccgaaggaca
      121 gctgattgaa caccgtttat tcggaaaaag ggactgtgac acgacttttg tcacagcccc
      181 taaaaaaaat aataaatttg tactattcta tgaagcttct tcttcagaaa actgactgtt
      241 ataaagatct gcatagaatc cgtctttttc catcaatgta tcgtggtttc ctgtttctac
      301 gatcgaacca tgattcatca caataatgtt gtctgcatcg cgtattgtag acaagcggtg
      361 agcaacaacg aaacttgtcc ggttttccaa taggcggttc atcgcttttt gaatcagtat
      421 ttctgttcgt gtatctacac tagatgttgc ttcatcaagg atcaggacat ctggatttgc
      481 taagaatgcc cgcgcaattg tgattagctg acgctgccct tgcgaaatat tgcttgcatc
      541 ctcgtttaat acagtgttat atccttctgg caatttacga acaaaatcgt ctacgtgagc
      601 agctttagca gcctcaatga tttgttcgtc tgttgcatcg tcgttcccat atttgatatt
      661 gtcatagata cttcctgtaa acagccaagt atcttgcagt accattgaaa actgtgcgcg
      721 caattcatca cgtgaaagat cacgggtatc tacaccatcg taacgaatac tacctccaga
      781 aacatcgtag aaccgttcaa gaaggttgat cagtgtcgtc ttccctgcac cagtcggacc
      841 tacaatagcg accatctcac caggtttgac atccaagtta aaatcagtca ttagcaagtt
      901 atctggtgtg tagccgaatt gaacattttc aaaacgaact ttgtatggtg tatctttttc
      961 ttctggaagg ccagattttt cattggacat ctcttcttca tccaacactt caaatacccg
     1021 ttcggctgaa gcaactgttg attggatagt gttcatcaaa cttgcaagtt gagtgattgg
     1081 ttgagagaac tgtgttgtat attgcaagaa cgcttgaaca tcccctaatg tcatgttccc
     1141 atttgcaact tttactccgc ctagtacagc gacgaacaca tagcctagat ttttaacgaa
     1201 attcatcaac ggcatgatga ttgccgaaat aaattgagct ttccaaccag cggcatacag
     1261 attctgattt tctttttcaa atacttcctg gtctttttca gtatgattga atgttttaac
     1321 aatggtatga ccaccatatg tttcttctac ttggttattc aataaaccta aacttttttg
     1381 ctgatctgcg aaaaacactt gtgatttcgg cgctacgatc atcacgatga tcaagcttaa
     1441 agggatcatc aataacgcga ctaacgtcaa ttgccagctg attgaaagca tcatcacgat
     1501 gaccccaatc aatgtgactg cactagttac aaattgagtc aaattttgct gcagcgtgct
     1561 tgcgatgtta tccatatcat tgattgctcg agacatgata tccccatttg tatgtgtatc
     1621 ataataggaa atcggtacac gattcatttt ggcttccaaa tcatgacgta attcataaac
     1681 tgttcgttgg gaaacacgtg tcataataaa ttgctgtaaa aagttgaata cagcagaaat
     1741 caaatacatc acgattactg tcgcaatgat ctgcgcgatt ttatcaaagt ctatcggaaa
     1801 ttttgttact tgttggcctt gttgcatctg ttgagcgcca gccattacac ctttgaatat
     1861 ttctgtggtt gctttcccca agacctttgg tgtttggatt tggaagatca cggctgctat
     1921 tgctagtaca aatacagcga tgatcgcaac catacgttta gacatatagc caaacaatcg
     1981 gcgtaccgtt ccccagaaat ttttaggctt ttcacctttt acaccgagat ttctgccagg
     2041 tccaccatgt cctggaccgc ctgctggtcc atgagaggga cgtgtgtttg ttttactcat
     2101 gctaagtcct cctctcttag ttgtgaatga acgatttctt gataagtttc gtttgttgct
     2161 aatagttctt catgtgttcc tttgccaacc agttttcctt catctagcac aaggatcata
     2221 tctgcatcca ttactgtact tactcgttga gcaactaaaa cggtgatact ttctttcata
     2281 ttcgttttca atgcttggcg aagattggca tccgttttga aatccaacgc tgagaaggaa
     2341 tcatcaaaca catagatatc tgctgttttg actaatgccc gtgcaattgc cagacgctgt
     2401 ctttgtccac cagagaagtt tcctcctcct tgttccacat ggctatctaa gccatcttcc
     2461 atctctgaaa caaaatcttt agcttgtgcg atttctaatg ctttccaaat catttcatct
     2521 gttgcatccg gcttaccata ctgcatattg tctcggatcg ttccagagaa cagaactgct
     2581 ttttgaggaa caaagcccat taattctcgc aaattatatt gagtcatgtc actaatgtcc
     2641 gttccattta tttggatcga accagattcg atgtcatata atcgagggat caaattgact
     2701 aaggtcgttt tacctgaacc agtcccccct atgattgcga cgatctcgcc cgacttggct
     2761 tggaaatcaa tatcttccaa tgcaagtttt tctgctccat gatatcgata attgacatga
     2821 ttgaaggcca atgttgcgtt ttttccagca aaagaaactg ttttaggatt ttcagggtca
     2881 tggataccga ttttttcatc caacacttca ttaatacggt cagctgaagc ttgtgcacga
     2941 ggcaccatga taaaaatagc ggaaagcatc ataaagctga tcaagatctg catcgcataa
     3001 gtcataaatg caatcagatt accgacttcc aaagtcatat ctgctatgta gtgtccacca
     3061 aaccaagtga ttgctacgtt tgtaccgctc atgatcaatg tcatcattgg catcatcaat
     3121 gcgacgatcg tattaacttt gattgccgta tttgtataat ctttattcgc taaatcaaaa
     3181 cgattttctt caaagcgtgt cttatcgaat gctcgaatca ctctgacccc tgtcaatcct
     3241 tctcgaaata ccaggtttaa acggtcagtt ttcttttgca tacttttgaa taatggaaca
     3301 gcaaagtaca tgattccgcc gatcaaaata atcattactg ggatgacaac taagaagatt
     3361 tttgtcaact gatgatcttt ttgataagca agtatgctcg cgccaatcaa cgtgattggt
     3421 gcattgatca tcatacgtaa aaacatttgt gtaaccattt ggatttgagt cacatcattg
     3481 gtcgttcttg tgatcaaaga ggccgttcca tatttatcaa acgcatcttt tgtcagactc
     3541 tctgattttt tatagacatc cgtacgcaat tgcttaccca gtttctgtga ttcacgagta
     3601 gcaaaaaatg tatttgcgat agcagctaag atactgatca aagaaaagcc gatcatcaca
     3661 aaacctgtat gccaaatata atcgacatct ccttgcgcta cccctttatc aataatattg
     3721 gaggtaagtg tcggcaaata taaatctgcc agtacttgga tcaccatgaa aactgcagct
     3781 gcaattgctg aagtcaagga gatccgtttt acgattttta gcatctagtt cccttctttc
     3841 tatttatata ctccgttttt cagccaagaa agtttcaaat tgaattcact gattgcttgc
     3901 tctactgagt aatcttcaga tgttgaaaat aagcgatacg aatgcgcaat tgttgtaaat
     3961 acagtattca tcactaattg gatcagtaat tccaattcat gatcattttt tactttcagc
     4021 ttcgtccgat cgatcaattc aagcaactct tttgcatctt gtttgtgttc tttatgtgga
     4081 tcgtgaggcg ttttttggcg actcgtatga ggagcgactt ttcttgaggc acggtaatcc
     4141 atgttcataa acaagttacg ataaaaagaa gcattctcgc cttccaaaat ctcataaatc
     4201 attttagaaa aataggattc gaatcctttg aatagatcac catcggattc tttcattagt
     4261 tgtaacatat ctttagagct gtcacgtctc attgtctcaa agtaataaaa ataaagatcc
     4321 tctttatctt caaaatactg atagaaactg cctctaggga tatccgctaa tttgacgata
     4381 ttagcaatcg aagcttcttt taagggtact ctagaaaact cgattctcgc agcctcgatt
     4441 agtctttttt gtttttcttt aggcaaatgg aaaaatgtct gtgtcggcat atggatcctc
     4501 ctttctttca agatgacaca ttgtcatatg acgctgtgtc attataacac ctcctacctg
     4561 ttttgcaaga catttgcata gtttttttca ttatcatccg atacattaaa aaagtgataa
     4621 gaggaatcct tccatttgaa ttaatgagag ttgcccatta aaatagccac atactaaaca
     4681 aaggatgaga taaatggccc aatcaattag tgtccaagac ttcaataaat tgcctctcga
     4741 tgctgacagc atcgttttag atacaagaaa taccttagat tacacaaaaa accacttaag
     4801 ccactcgctt tctatccccg ctgctatctt gccaagacaa ttaaaaaatc tagatccaaa
     4861 gaaactttat tatattctaa gctatacagg caggcgatca gaagcattag ccgatcaact
     4921 tactgctaat ggttttcgtg ctgtttatat cattggtggg atggaagctc ttcagtcgag
     4981 tgttgcttga atattgcttg ttagattcaa aagaggctgt gacaaaaaat cgtgtcacag
     5041 cctcttttat accctgtctt tttttagtta tttattcttc aaccttatca atatgacttg
     5101 atagcctttt ctttttctca tagttataac aatcatagca ataaaaggag aaggtaagca
     5161 tatggcatct gttttagtag tcaaaggtca tcccctaact gcagaagaat cgcgcacagt
     5221 taaggcattg acgtcttttt taacaagtta taaagaaaat catccagatg atgaagtgac
     5281 tgttttggaa ctttatcgcg atgatattcc ggaaatcgat gaagaattat tatcaggttg
     5341 ggaagcatta cgtgctggtg cagaattcac ttccttatca gaaagtcaac aacaaaaaat
     5401 tgctcgtttc aatgaattga ctgatcagtt ccttgctgct gataaaatcg ttatcgcaaa
     5461 cgccttatgg aatctaaata tcccaacaaa attaaaagct tggttcgata ccgtcaatgt
     5521 agctggaaaa acgttccgct atacagaaaa cgggccagaa ggattagtga caggtaaaaa
     5581 agcactgcac atccaatcta atggcggtgt atacaacgga caagactttg cctctcaata
     5641 tgtaaaaggt attttaaact ttgtaggcat cgatcaagta gatcagctat tcatcgaagg
     5701 aatcgattat gaccctgacc gtgcagatga gttgatgcaa aatgcattag ataaagctgc
     5761 tgctttaggt aaatcatttt aaaaattgag ataaatgcat acaaaagaga cagaggaaaa
     5821 aatcttcaaa gcagcatttg taccttggat attttcccat ctgtctcttt ttgttattct
     5881 ttctgctttt tcaacggatt ttcttcataa agagaagaga ttgttgtgta ccattcaaaa
     5941 acatgagtaa tcactacttt agctgctgca taaacaggaa tccccaagat cacaccgatg
     6001 attccgaaca atttcccaga agtcagcaga actaataaaa tcgttactgg atggattgct
     6061 aactgattcc ctagtactaa tggagagatc aagcgtcctt ctattgtctg ctctactgca
     6121 aaaacgatca gtactttgat gatcatgaat ggacctgcta caatggctaa aaagatagcc
     6181 ggaatcatcg ctaaaaatga tcctaagtaa gggatcaggt tcaaaaaacc cgcaataatc
     6241 cccaacgtga cagcatactc taaaccaatg accgcaaaac caatcataaa catgattgcc
     6301 acagcaaaag ccacagttag ttgtcctctt atataagaag aaacttgact attcatttca
     6361 ctcagcacat tcaacgtcgg tttttgcatg cgtgtcggta aaaatttgac aaaataaggt
     6421 gctaattgtt taccgtcttt caatagataa aataagataa acggcatcgt cagcagagcc
     6481 actaaaatag tcgctaccgc gccgacaaaa cttccaagac tctgaactgt actcttagat
     6541 atatcttgga tcatatcgcc tgccgaattc atgaacttat cacctgctgt ttccaactgt
     6601 tcgcgaaatt ggttgaacag cgggtcccgc aaaatctcgg ttaatttatt atcaatcgta
     6661 tctacatatt gagggaagtt actgatgaag ctcactgttt gttcctgaat cttagggatg
     6721 atcactacgc tcccccatgc gattagtgca acaaccaaaa caaacagccc aatgatactg
     6781 taaagccttg gtacttttcg cttttcaaag taatcaacta ccggattcat caagtaatac
     6841 aagattcctg ctaaaatgat aggcagacct acgattgcta aaaattgcca gattggtgca
     6901 aacaaatatg aaacttttgt aaataaaaag acgatcagca atattaacaa tacaacaagt
     6961 aaggctgtga ctacttgatt atttaaaaac cagcgccaaa accacgatac cggtctgttc
     7021 ttcttatttt ttccttccat aattcctcct gttagttata aaaaatttgg cttcccaaac
     7081 caatagcagg cagtctatgc ggatgaagat agattccatt tgcaatttgt ccttcttctg
     7141 gacaagcatc aaaaatcaat gatacgtgag ctactgtctc taaattccca ttggccatcg
     7201 gaccgacata atcgatcgta tatacctgat catcaaaagc aattgttccg cctgctttca
     7261 aagaaaaagg ttcgtctttt gatacttctt gaatcaccga atattttcgt aaggcagctg
     7321 ttgctgtttt atcgaacaaa atcagcatgg gttcttcctt gtttattgct tctgtcccaa
     7381 tttctgtaat ctttgcctga atcattgcac tctctccttt aattgctttc aaaaacagta
     7441 taacacattc tcattcttta gccgtgtgga ataattatgt gatagaataa aaacgaaaac
     7501 tatttcatta caattaggag gaatcagctc atatgatcga aaagataatt ttaggaacct
     7561 atacgcgtcg cgaaagtaaa ggaatctata cgatcgacct tgatacagaa aaagaagaat
     7621 tagccaacct ttcattagct gttgaagaaa atagccctac ctatgtagca aaaagtaaag
     7681 ctggcaatct ttacacagtt actagtgtgg atggattagg tggtgccggt gcgtacgata
     7741 aggattttca ttttttgaat gcggtaacag agtctggcgc tcctttgtgt tatgtagcgg
     7801 ttgatgaagc acgtcaatta ctatacgggg cgaactatca taaaggtgaa gtaaatgtct
     7861 accatatatt aggagatggc gaactgaaag cagcagattc aatattccat caagaagcga
     7921 caggtcctca taaaaaccaa gatcatgcgc atgtccacta tacggatctg actcctgacc
     7981 aacgattagt cgtatgtgat cttggtacag atcgtgtgta tacttatgat gtgtccgaaa
     8041 acggcaaatt gaatcttgta actaccttca ctgcagagcc aggaacaggc cctcgccatc
     8101 ttgtctttca tccaaatgga caattcgctt atttatttgg tgaattagac agcacagtcc
     8161 gcgtgctttc ttataataaa gaaacaggtg cttttgaaga attacagaaa atatcgacct
     8221 tgccagaaga attcgacggt gaaaatggag gggcagctat ccgcatttca aatgatggca
     8281 agttccttta tgcttctaac cgaggacata actcgattgc tgtattcgca gtttttgaag
     8341 atggttccca cattcaaaac aagcaaatca tctcaacaga aggggatttt ccccgcgatt
     8401 tcgcactaga tccaagcaat aattttgtcg tgtgtgccaa tcagaacacc gataatctga
     8461 cattatatcg ccgtcatcct gaaacaggat tactggaatt actgaaaaaa gatgtctatg
     8521 taccagaatg tgtctgtgtt tattttgatc gttagtaaga aaaggagaat gaaatgaatc
     8581 agcaagacgt attagacaga ctacgggaag aactaaatat tcctttcttt gatgggaaaa
     8641 tcgaagataa agagtatagc gaagaggaat atcagaaact caaagccgat ttacagaact
     8701 actttgaaca atatgtacag aatgtagaaa actaatcagc tttccatact atctgaaaag
     8761 aacatcagga caagactttt ccgtctatcc tgatgttctt ttctacaaat aaaaaaccgc
     8821 cgagatggtt agactcgacg gaaaaggagt atttactcga ttttgagtaa gtacaaggtt
     8881 gttgttggtt ataggtatgt cattatcata aaggattttg atcactctat cataaaggta
     8941 atattacatt tatattagat aactctagtt tttattgtta tcaaagattt cttttatttt
     9001 ttcaacaaca aattagtcat tttttggatg gcagctgtca attggtctgt cgcttggtct
     9061 tgttttgctt cagatgtatt gaatagatct tcatctaccc ctgattcaag atcgatactt
     9121 tggatcattt cttcacagcc tgctacatat gaaagataag ctttttcaaa atttttatga
     9181 atgcccattg cttttgctgg tggacgcaaa gtactgactt tcttaagcat tgcccgatat
     9241 ttttttgttc cttcttcaaa taacaggatg atctcttcaa gagtcgattt gtccagttca
     9301 cttgtttttc cttcatcaat tgcgtttctg atcacttcat atttcggatg cattccttct
     9361 ccgattgctt ctgtttcctt gacgatttga tcgatggact gcacataata gccaatattc
     9421 ggtaacatgt tcgttttcct actttctcca ttgttgttat tatttattct acttgttttt
     9481 atcctcaaat gacaagtact tgaaaaaatt taatggtttc tatacagctc gccattctta
     9541 ttcgtgctca aagaaaccat ctgctaaact atattgtttc cctgcgacaa tgtcatattg
     9601 gatcaattga tattcgtcgt aaatctcttg ttgcgagcga ttgaattgcg cttctttata
     9661 ccactgtccg ttttgatagt acagttctcg ttcaaacgcc ggaagttcct gttctaatga
     9721 taaaagcagc tgataaaagc catttgttgt ctgattcgtc tgttccatta gattcgctgc
     9781 aaaataaaac ggactggtga ttgcatcgtg agtcgtttgc ttttctaatt ctcctttact
     9841 gtcgaacata agaaattgtg tttcatgcaa tgtttgtttg tcattttttg cttggatcgt
     9901 atctgaatag atccctggaa gatgatcccc ccaaaaaaca actaaagtcc ttctagaaag
     9961 attcttcaat tcttccgtga actgcttcag tgccgtgctg ctataggaaa tatcttgcag
    10021 ataattctct aagtcaagtg tcccacttcc atctgaagtt tttgcaggat agtctagatt
    10081 atcatacttt ccatcgtagg gcatatgtgt ctgcatcgtg actaaatgaa tgaactgagg
    10141 tgttttttct tccttgagaa gtgtcattac ttctttgtaa gctgactcat cagaaatata
    10201 tggattattc tctatcgtat ccgtataggt catcgtacgc tcgctgatga actggtcaaa
    10261 tcctaatgtc tgataaacat cctctctttt atacatcgaa gtattgtatg gatggatcgc
    10321 tgtcgtctgg tatgattgtg cgtttaacgc tgaaacgata gaaggaagct gatccatttt
    10381 tggtacaagc atcgtgtaag gggtggtgag ttgcgcatta aataacgcca tagaaaaacc
    10441 agtcaatgct tcaaattcga tatttgctgt tccaccgcca tagttttgag aaagcatatt
    10501 gccactatat gtttgatcag ctacttcata ataatctgcc aatggctcac cagatacttc
    10561 tacgccgttt aatcgactag gatctgagaa actttcactc atcacgaaca cgatgttcgg
    10621 cgactcttcc tctacagttt tatttttttc atcggctagc ttctggtatt tttcagtgat
    10681 ttctttgatc ttttctttcg aatatccttc aggttcatcc attggttcta ccttcagatt
    10741 gtacaaaaac ccaccgataa aaccagtgtt atagtagttc attttctggc tgtaaggtat
    10801 ccatagtgcc gttttattat atgcttttcg caacaaatta tcgggattgt tgaaattact
    10861 gatataccct agcagtccaa ttgccacaag cagtgtcgtt aatcggatca attggaatcg
    10921 ccttcctttt ttcaggcttc gaaacatgta ccagcaaaac aatcctatca cggttcctgc
    10981 ggcagctaag atcactgtaa acagcatagt gccggtcata tctttcagca atccgatttc
    11041 agtgatcatc ttcaaatcgt ctggataaat cggttcttgc cgataactca ttttcatata
    11101 atttgcaaaa cctaatacac cgatggctac gacatacgta agggaaccta aagggacaga
    11161 tcctgctagt gcaatcagaa aaataagaat aatcagcaag acgagacagg ctaagaagaa
    11221 tttttccgta tgccaagaaa aagcaaattt caacgcaagg tctacggata gatcattttg
    11281 acaccactgc aaaaataaat tactaaaaac aacaagaaaa aagatactga tgattgctgc
    11341 tgttcctttt aaaatctttt tctgtttggt cgaaagtctg cttatatatc ttttcaaatg
    11401 cttgctcctt catttctatc aataaaagaa tgttgcttct cttattttag ttgtacgaaa
    11461 ttcgaaagta aagaacggaa agaagaatta atgaaatcca aatattctct ttctttatgg
    11521 cctttctggt ttctttaata agcggacctt tcgtactcca gaaatttttt ctagctgttg
    11581 tttcacttga ttgagctgtt caaaatcagt actgtctatg tcaatcaata tgtagacatg
    11641 ctcattctta tggttacgcg atatatctgc gatcgctagc tcgttctcat tcagcagaga
    11701 aaatatctct gctaatatat tggttttctt ttgataaaat atagtgaatc gaaacggcgc
    11761 ttggaaaaac attcgtgcgg atggataatt gaccgcttct ctaaccgtac cgaacaaaag
    11821 ataatctttt aaggcttcaa ctgccaaacg tccgctgtct gccaaagctt cctgagtcga
    11881 tccccctaga tgaggcaaca taagtatacg gtcattttct aagaactctt cttctggaaa
    11941 atcagtcaag tatttagcca gatgttgttt ttccaatgct tgcataacag catatttatc
    12001 aacaatttca cttcttccta cattgataag tacagcatct tttttcattt tttctatatt
    12061 cgcctgatcg atcaatcctt ttgtatcttc tgtcaacggc agcatgacta cgatgtaatc
    12121 cgaggtagaa agaactgttt ctaaatctgc ttgccgaaca taatccaact gggcatcgcg
    12181 gatagaataa cccaagacat ccatccctaa gctatagcaa cttagcgcta cttttgtgcc
    12241 tatcgctcca agaccaagaa gaccgatggt tttgccttgc aattctcgtc ccacataagc
    12301 acttcttttg ttttctgcct gttctaaaat attaggacct gttagtgttt gtaccatacg
    12361 acttgcttcg attatcggac gggaagataa gagcaaacag cacaaaacaa gctcttttac
    12421 tgcattagca tttacacctg gtgtattcat gacgatcgtc ccgttttcag aagctttttc
    12481 aacgttgatc gtgttcaccc caacaccagc tcttgaaatt gctagcaaat ctggtgtaag
    12541 ccattcatct ttcactttcg tactacgaat aactattcct tcggctggca aatcatctat
    12601 tattttgaaa tattcccctt gtaacttttc tatctcttgt tctggaatag catcaatcaa
    12661 atgaacgtga tacataaaac cccctcctta ctaacaagta tctcgaaatt tctgcaatta
    12721 gacaactgtt taccatttga cttcctagaa gcaaaaagag cagttagagc agagtaggct
    12781 gagtgataaa aataaggcta tgacaagtta ctgccataag ccttattttc gagagcaaaa
    12841 tattgagggt gagatatctt gataaatggt gttccgttag ctgacattga taataagact
    12901 aaatttcaaa aaagttgaaa agcaaatttc gtcaatctct tcttatttct taaaactaag
    12961 tggctttttc acaacctctt tttatctaat aaccactgtt tccaactcaa ctaattttgc
    13021 ccacgtttca atttgatctg ttgttagatt tagcgagaca acggtatgat gaccgccacc
    13081 tgcctgaatc catgaatgga caccttcatg gaaattcggt ttagttttcc ataacacacg
    13141 tgcaacaggt aaattaggtg cttcagtcgt tggttcaaag gcttctactt cattgatcag
    13201 cagtttataa tgcgtaccga aatctgccat cgatacgact accccttctc ctgctttccc
    13261 atcaaataca agacgcgccg gatcttctct atctcccatt gataaaggag aaacaacgat
    13321 tcttggtttc gtcgcagcaa gcgtcggatc tacttccatc atatgggatt ccaagattgc
    13381 ttcttggcca ctagctagct cgtaagtata atcttccatg aatcctgtat ctttccctcg
    13441 agccatgatt ttcagcaacc gatcaatcgc tgcagttttc cagtcgcctt ccccagcaaa
    13501 accgtatcct tctgccatca aacgttgtac agctagtcca ggtagttgtt tcattccata
    13561 caggtcttca aaattagtcg taaaagcgtt atagcctcct tcttctaaga aacggcgaat
    13621 accgatttcc tgctgagctt gtacttttac atgttcctcc catgtctttt cttcataatc
    13681 accatagtcg aaggtataca attccttgta ctcttcaaat aattgatcga cttcttcgtc
    13741 tgatacgcga tcgattactt gtacaagatc tccgatacca aaataatcaa cagtccaacc
    13801 aaattgaatc tgtgcttcca ctttgtctcc ttctgtgaca cccacgtttc tcatgttgtc
    13861 accaaaacga gccactttta ttccaaaact ttcattatag gctactgcaa catccatcca
    13921 atcagcaatc tctttttgga tctcaggtcg tttccagtag ccaacgacga ttttattttg
    13981 tttatttaat cgagcattga tgaacccata ttcgcggtca ccatgagcgg attgatttaa
    14041 attcatgaaa tccatatcga tcgttttcca aggaatgctt tcgttatatt gcgtagctaa
    14101 atgaagcaat ggtttttgta gaagctttgt cccgcggatc cacatttttg ctggtgagaa
    14161 agtatgcatc caagtgatca cacctgctac ttcttctcga taattgacct ctttcatgat
    14221 ttttgtgatc gtatcagcag taactgctaa ttcttgaagg cggattggat aaggcaattg
    14281 gccattttca ttcagttcat cgaccatttc ttgtgcatgt ttctttactt ctcgcagtgc
    14341 ttcttcccca tataaatgct gtgatcctac aacaaaccaa aattcttttt ctccaatatt
    14401 caacataatt agccactcct tttatttgtt ttgtccgtaa tacgcatttt ttccgtgttt
    14461 tcgtaaataa tgtttatcta aaatccgttg aggcagctct tctgaaaatg aattgagctg
    14521 tctggtaaat aaattcatct tgcatacttc atctagtacg actgcgttca ttaccgcact
    14581 ttgcgcatct ttcccccaag taaatggacc gtgtccgtgt aaaagtaccc ctggaattgc
    14641 taagggatca attttgcgtt ctttgaatgt ttctatgata acttttcctg tttcatattc
    14701 gtacccgctg tcgatttcct gttgtgtcaa aaatcgagca caaggtaccg atccataaaa
    14761 agtatctgca tgcgtcgtcc ccatcgcagg aacatccaat cctgcttgtg cccagatcgt
    14821 cgcccatgtc gagtgagtat ggacgattcc tccgatttga ggaaatgaac gatataaaac
    14881 agcatgagta ggcgtatccg aagagggatt gagtttacct tcaatgatat gattgtccaa
    14941 gtccacaacg accatgtcgt ctgctgtcat ctcttcataa ctgactccgc taggtttgat
    15001 aacgaaatat cgtgtttcag gatcaaaagc gctcacattt ccccatgtat atttgacgag
    15061 tccgtgttta ggcaagtcaa gatttgcttg gtatacttct tctttcagtt gttccagcat
    15121 tttctatcac tcctttttct tgcaattgat gaatcgctgt tttttcaatg tcgatcccct
    15181 cacggtaacg tctcataaat atctgatagc ctgctatttc ttctgctgaa ggtgtgatgg
    15241 tgattccttg gtcttgtcca aacacgtctt ctgccaagaa gttttctaaa gacttcccat
    15301 gtcgatccat catataggct gctaataacg cgattcccca cgctccacct tctccggctg
    15361 tgtccatcac tgtaactggt gcctccatag cagatgctag aatccgctgt ccaacttctg
    15421 gtgttttaaa aatcccccca tgccccacta aacgatcaat ttggacattc tcagatttca
    15481 atatatccat tccgattctc attgcaccaa aagcactggc taaatggatc cgcatgaaat
    15541 tcgctaaatc aaaacggcta cctggtgtac gtacaaataa tggccttcct tcatttactc
    15601 ctgtaatgtt ttcaccggaa aaataaccat aagaaagtaa tcccccgcaa tccgtatcgc
    15661 cttctagcgc tttgttgaat aataccgtga ataatttatc tctgcttatc tccataccca
    15721 aagaattggt aaattcttca aaaatactga cccaagcatt gatatccgaa gagcagttat
    15781 tcgtatgaac catgcctact agttctcctg aaggtgtagt gaccatgtcg atttccggat
    15841 ggacattttc tagttctttt tctaatacga tcatagcgaa ggcggaagta ccagccgaaa
    15901 tgttccctgt ccgtttggct acactgttcg tagcgaccat accggttcct gcatcccctt
    15961 ctggcggaca aaccgggatt cctggtctca aatttcccgt agggtcgatc agataagccc
    16021 ctgattcgct taacttgcca gcttcttctc ctgctactag aactttaggc aaaatgtgat
    16081 ccaagtcaat cgctacgtgc gctttttcga ttaactgacc aaaaatattt ttcatttctt
    16141 gatggtaggt tttcgttgaa ggatcgatag gaaacatgcc tgatgcatct cctacgccta
    16201 gtactttctc accagtaagc tgccaatgga cataacctgc aagcgttgtc aaaaaattaa
    16261 tttctttcac atgttcttct ttattcaaaa tagattgata caaatgagcg atactccatc
    16321 tctgcggaat attgtattga aatttttccg ttaatattcg ttctgcttct tcagtgattg
    16381 tatttcgcca agtacgaaat ggtactagta actgttcctt gctatcaaat gctagataac
    16441 cgtgcatcat tgcactgaac ccaatcgacc cgattgtcgt aagattctcg ccatagattt
    16501 cgaatacttc tgctgccatt tttcggtaac tgacgcgcag tcctttccaa atatcttcta
    16561 atgaataggt ccagatacca ttttctagtt tgttttccca ctcataacta ccagcggcaa
    16621 taggagtaaa agatgaatca atcaatacag ctttgatcct agttgatcca aactcaatcc
    16681 ctaaagatgt acgaccatct atgacatcta acatactttg cgcatttact tccttcataa
    16741 tgatttaact ccctccttct cgtcaaacct gatcaaaccg tctttttagt agcgcttaca
    16801 atgattattg tatacttttg tacgtacatg tcaagcggtt atttacaaga atacaataaa
    16861 aaacacttgt tttgtacgta cataagttat aaaatgaaat tgcttacaaa atctgatcaa
    16921 ccgccttctc gaaattctag aaggagagaa tacttatgaa aaaagaaaaa aaagtttcct
    16981 catcgtttat ttattttttt ggcgcatttg gcggcattct atttggatat gatattggtg
    17041 ttatgaccgg cgccttacct tttttacagc atgattgggg tttggcaggt aaagcttctt
    17101 tgataggatg gatcacgtct tcggtcatgt taggtgcgat ccttggcggc tctttatctg
    17161 gtcttctttc tgataagctt ggacgacgaa aaatgattct tctttctgca cttattttta
    17221 tggctggttc tgtcctttct gcatctgccc ctcacaatgg ttcttatttt ctgattgcag
    17281 caaggattct tctaggttta gctgttggcg ctgcatctgc cctagttcct gcttatatgt
    17341 ctgaaatggc tcctgctaga ctaaggggaa gattgtcagg gatcaatcaa gtgatgattg
    17401 cttctggcat gctcctttcc tatgttgcag attatttgct aaaagtgttg cctgaaacga
    17461 tggcttggcg cgtgatgtta gggctcgctg ctgtccccgc gctgatttta tttttcggtg
    17521 ttttagctct accagagtca ccgcgttttc ttatgcaatc tggccgcttg gaagaggcaa
    17581 aaagagtatt gaactatatt cggacaccaa aagaagctga acaggaattc gaacaaatcc
    17641 agctgaatgt caaacaagaa aagacaaccg gaacttcttg gcatactttg tttttagaaa
    17701 aatatcgttc cttagtcatt gccggtattg gtgtagcagt attccagcaa tttcaaggag
    17761 ctaatgctat tttttactat attccgctga tcgtagaaaa agcgactggg catgcagcga
    17821 gcgatgcatt gatgtggccg atcatccaag gaatcatttt agttgctggt tctttgctct
    17881 ttttggttat tgcagacaag ttcaatcggc gaactttatt gaaaataggc ggtagcgtga
    17941 tgggactttc attcatccta ccagctgttt taggaactgt actggatgct catacaaatt
    18001 cgttgttgat tctcttgttt ttatgtattt atgtcgcatt ttattcttgc acatgggctc
    18061 cactgacatg ggtaatcata ggcgaaatat tcccactagc tgtccgcggg cgagcatctg
    18121 gcctagcctc ttcttttaat tggattggtt ctttcctagt tggcttgctt tttcctgtga
    18181 tgactgcttc tatgtctcaa gaaatcgttt tcggcatttt tgggatcatc tgctttttag
    18241 gggttttatt tattcaagag atcgtaccag aaactcgtgg gaaatcttta gaggaaatcg
    18301 aacaaagtgc atctaaaaaa acttatccta aacgtatttc tatccatcat tcttaaagag
    18361 gttgtgacag aagtggtcag cttcaagaaa taagaaggaa ccgcttagtt tccagtcaca
    18421 aggaacaatt tcaaaaaaca gcttctcatg tttgatgaat attgtgactt gtgaccagtt
    18481 ggtaggagaa caccgtttag tggagaggtg gtgaaagaaa cgttcagcct tgagcgatga
    18541 caaaagctct cacaaacatt gcgacgagta accgtaggag caataagagg cggtaaaaac
    18601 ccgtctctta tttttcgttt tctttcactg tttcccgttc aactagtaca ggttcataga
    18661 gaatatttgg ctgtgcctgt cctttttcaa tcgttgtgac gatccaccgt gcggcatctt
    18721 gtcccaactt ttcttttgga tgcgtcaatg ttgtcaattt tttattccct aaatggctta
    18781 aagaagaatc gtctgttcct acgatcgata ggtcatctgg aatatgatag ccattttctg
    18841 tcaacttatc tagcattaaa ctagctattt gatcgttata gcaaatgatg ccatctaaag
    18901 cttgttcttc tttcaaccgt tgtactgttt tttcagcgat tgtttctcgt gtttccgtgg
    18961 tgaaagtaat gatatcttcc gtcaaaaaac gcacattata ctgttcacac gcgctgataa
    19021 aacctttcat cctgtatttt ccttgaagat cgtcgatttt tgtgatgaac aacagacgct
    19081 gatgtccttt ttttatcaaa tattctgctg ccataaaacc gactttcaca tcatctaaac
    19141 aaatataaga ggcatttaac tcttcataag cagcattgat catcaccatc ggaatgcctt
    19201 gttctctcaa agcaacataa agtgctaagt ttgggttata ctgattactt ttcgtaggct
    19261 caacgatcaa accatctacc ccataagcaa tcattttctt caaacactct ttctccaatt
    19321 cgtgatcgtt attcgtactg gctaaaagca atgaataccc agattctcgt aattcatttt
    19381 cgattcctcg gataatcgac ggaaaaatat aatcagagag atatgtggtg atgacaccga
    19441 tcgtttttgt tctgttcaat ggtgtttttt ctttcttata gctgtcatct acatatgtgc
    19501 ccgacccttt ttctttacgc agatagccct catttaccaa cacagcgatt gcttgccgaa
    19561 tcgtatgtct gctgacgtca tatatttctt gcagcttgaa ttctgaggga atggttgtat
    19621 ttacttcgta ttcctcacga aggatctttt gttttatctc ttctgcaata tcttgatatt
    19681 ttgccatttg ccttgcccct ttttatttgt acgtacatat atcataacga gtctgcaagg
    19741 tttattcaag caaaaatcaa ggtttcttgt gctcataagg catacggaac aggttcacca
    19801 aattctggaa atccttgctc attccacgta aagcattgcg cgttcgcgtg ccgattagga
    19861 ttgtctaacg gatccccttt ttggttcttc tctggtcgag catgatagat caaaatatca
    19921 aagcacccgt cttctgaaac cgtaaacgag ttgtgaccag gaccaaattg cttatttttt
    19981 tcagaagaaa cgaatactgg ctccgataat ttatgccatg attcttttaa taaaagattc
    20041 ttgtgctcat cagcccacag caggcccatg gcatagtttt catctgttgc actaccagaa
    20101 tacgtaatga atattttccc attgcgagta aggactgctg gaccttcatt tactgaaaaa
    20161 ccccgttttt cccattcata ctcaggtata gaaaggagga tctgcttccc ctttaacgtc
    20221 caaggattat ccatttcgga tagataaaga ttagaattcc cagtaatttc aggatcttgt
    20281 tgggcccaca cataatatag ctttccttga gaagagaaag ttgttccgtc taaactgaaa
    20341 gtttcccttt tcgtttttat ttgtcccttt tctatccaat ctgtattcat tggatctata
    20401 tgctgatttt caagtacgaa catgcggtga tgatgagatt catcacgtat agttttatga
    20461 ttgcttgcag caaagtaaat ataccatttt ccattgatat aatggacttc aggtgcccag
    20521 atcaattcac tcatcggtcc ttcttcatga gcctgccata caatcaggct tgcagcatgt
    20581 tctaattcat tcagtgactt tgcccttctt aattcaatca cttggtagcc tggaaccgat
    20641 cctgtaaaat aataataacc atctgtatgt ttatataccc aaggatctgc ccgttgccga
    20701 acgataggat tattataaag tgtcttcatc ataacaaatt tcctcacatt ttctttattc
    20761 taattacatt ccaagagtat ttttctatcc ctacatttaa ttcgtcatgt ttttctattg
    20821 aaaaatagtt tatttcaggt tttatttttt ctggttcttc acgtgtattt ttgtccaaca
    20881 gatcgctact ggttaatgtg tagtgctctc cttgatctag caaattgaaa tcatgttcaa
    20941 tcgttatctt ttgttgttca tttgtgcgat tgatcaagaa aatagtcagc tgattgccgt
    21001 tatctacgat cacactgtcc acataaggaa cattttttat cttttcacaa tcataaacag
    21061 ggcaaatgat ttgttgtttc aatacttgac ctttagcata tttcgataag tgttgcatca
    21121 cataataagt tggattcctc catgcttgtc ctttagcatc tgtcagtatt aaaggtattg
    21181 tgtttactaa caatgattga caactaatct ttacgcgatc tgcgtgtcgt aaaatagcca
    21241 gccctaatga accaaataat aatgtatctt ccatagtaaa gtaacaccaa tcgatgggac
    21301 taccgacttc aaaatcccta tgtctttttt ccggttgggc atgtacattc cattcatcaa
    21361 acgctagata cattgttttc tcacttctca aatatccttt tacataatca caagtagcaa
    21421 cgatttcttc aatttgacga tcgaatcgat aagcttttgc aaggtatgtc gctgtatcat
    21481 cacgctcatt tttaggaggt ttagtcaagt cttcttcatc atacttatca atatagttat
    21541 gcaaagctaa ataatctaca ttctcataag cttcttctaa tgcgatacga tcccattcag
    21601 ggtacgatgg taaacgtggc gtagagcttc caactaagat tgtttcaatt gaatcatcca
    21661 ctaacttcat gacttttgag gcttcatttg ctaacctacc atattcataa gcactcttag
    21721 cccccacttg ccatggaccg tctagctcat tccctaaaca ccataattta acgccaaaag
    21781 gctttttttg cccatttttt attcttaaat cactccagaa ggttcctttt ggaaaattac
    21841 aatattctac taaatttttt gcttcatcaa ttccttttgt tcctaaattc accgtgaata
    21901 tcggtttcgc ttgtacatga ctgatccatt taaaaaattc gtggagtcca aaagaatttg
    21961 gttctatacc tcgccatgct aaatcaattt tttttggtcg ttgttctttc ctacctacag
    22021 tatccaccca atcataacca gatgtaaagt ttcctccagg atagcgaatg acacctaatt
    22081 ctaattcctt tacataagag aggacatctt gtctaaaccc gtcaccatca gctgtttcat
    22141 ggcccggttc ataaatccct gtatagacga cacttcccat atgctcaaca aatgagccaa
    22201 acagccgaga actgatctct cctaccgtaa aatcctctct gatttttact ttcacttctt
    22261 cgtccaacag ctttccctac ctttcatttc ctatagtcaa gataatagat acaagtttcc
    22321 atacgccacc agcaaagata aaaataaaag gagggaaaag aaatatgagc agtacaaatc
    22381 ctaataacaa tacgcaacaa agaatatttc tcaaaaaatc aaaaaatact ttccatgcac
    22441 tttgttcaaa aatttgtaaa aatgtgatat ctttgttttc agaaatcaca tatatccagg
    22501 ataaaagaaa catggaataa ataagtaaaa ctacatatcc actaattgaa agtacgattg
    22561 tctgttcttc taataattga ttaacaagaa aataaataat gatcgttaac agactaagga
    22621 acaagttctt accaaaatgt tgctttattc cttgaaagaa aaaataaatg atatttcctg
    22681 atccctcacc tttccattgc gccattacat aaaaaacagc acatgtagca ggcacgatag
    22741 taataacagg caaacacacg attacccaga gaatacctaa taagatgtaa tcagaaacca
    22801 caatcaactg tccataaaat ttagtctcaa ctattttcat cttcctcact ctttcattcc
    22861 agacatagct gttccttgaa caaaatattt ctgtgcaaaa atataaacca ctagtaatgg
    22921 cagcattgaa ataaccgttc cagccattac aggtccataa aaagaaatgt tctgccctgt
    22981 aaataaagct aaccctgctg gtaaagttct catttttgaa ctacttgtca atatcaatgg
    23041 ataaagcaag tcattccaac tattcatcag cgtgaaaatc cctaatgata aaagagtagg
    23101 tttgctcaat ggcaacatga ttttcaaaaa aatattaaac tcacttaatc catcaatgcg
    23161 tgctgcctct tccaaagaat ctggtaaagt aataaaaaag gaacgcatca tgaagatacc
    23221 aaatgcagtt gtcatacgag gaatgatcaa acctgcataa gtatcaagca tgccaagcaa
    23281 attgacttca ataaatagag gaatcatgaa gacttggaat gggatcatca ttgtcagcaa
    23341 aacgaaatag aacaaaactg attttccttt gaaacgcata cgagcaaatg cataccccgc
    23401 aagagaatca aagaatacag aagtgatcac tgtccctcca gcaaaaatca ctgtattttt
    23461 gatgtaatct aataaaggga tcgttgtcca aaccttaata tagttatcta gggtatagct
    23521 atctgcaaat attctaggcg gaaatgagat aatgtctttt tcgtgtttaa aagaagaaat
    23581 aatcagccac aaaaaaggaa acgcaataac caacaatata actagcatac taatcgttcg
    23641 aatgattttt ttaccactaa ctgcttttcg actattcaca gtaactgtaa tcgagctttc
    23701 tggtgccata caggtttccc tcctatttca tttgtttttc tttccgtgac atgtacacat
    23761 tagtggagat agctatagtt gcaacaatga taaacaaaac cgaagacagt gctgatgcat
    23821 agcccaattc ataaggtgct gtaaatcctc gactgtaaat atattgaaca gctgtttctg
    23881 tcttaaattg tgggccacca gcggttgcaa catatacttg gtcaaacact tgcatcgaac
    23941 caatcagatt cgttaaaata caaaaaccta aggagggaac gatctgaggt agcgtaatgt
    24001 taaaaaactg ctgtcgattt gttgcaccat ccatttgagc agattcatac aaagagggag
    24061 agattccctg aatagcagtc aagagaatcg tcatagtaac accaaaattc ttccaaacag
    24121 tcatgatggc taccgtcggc atagcaaggg ttggatcgcg aaaaaattga gggatcggca
    24181 agccgacttg tgaaaacaag taaggaatcg cccctacatt cggatcaagc aacatagaaa
    24241 aaataatcgc aattgacgtc aatgaacaaa taactggaat gtaaaatgtc gaacgacaaa
    24301 aacgattgaa tctggtattt ttagataatg ctactgctgc taataaacca acgataattt
    24361 gtgttggcgt ttcgagtacg gtgaaatata aagaatgaat caacgaatta actgctcgtt
    24421 catcactaaa tatacgtgtg aaattttcaa aacttacaaa atttcttgat gtaaagaaaa
    24481 tattcaaatc tgtaaaacta atagcaaatg ttcctaaaag cggtatgaca gtaaataata
    24541 ataaaactaa aaaagatgga gttaaaaaca aatacgcagc acgatcagga cgattccaat
    24601 atttggtgaa tccgttcata tagtccacct catctttcat tttgataaaa tatacaatct
    24661 tggtttaaac gaatctgaat aagatatccg aacaatcgct gtgatttttg caataacacc
    24721 tatctgcaaa tactaggtcg atcattcaga tatctgtatc ttgccaacag tctatcctgt
    24781 ataaagttct gtactatttt tgcagtaatt gattgatggc atcatctgca tcgttcatga
    24841 gtgtctcagg atcttctcct gctaataatt tttcaatcag tggattgatg atatcgttat
    24901 tgatcgcaga gatttgggta aaacctggta aatatggctc tgcatagtcc atttgtttcg
    24961 ataattcaga tacaatagga tcatttttta cttcttcatc ttttgctact aaatccaagt
    25021 aggcaggaaa accattttcg atactccatt ttttaccaat ttcagttgta ttccaatatt
    25081 tcaaaaactc atagacagct tcttttttat tattatctgt acttgccgga atggcatatc
    25141 ctacgccatc taaaatagct gtttttttgt ctgaatcact cccttgtggt aaggtagtca
    25201 cattataatc aatctcgttt gctttcaatc cgttatttaa ccatggccca ttgatttcaa
    25261 tggctagttg accagcattc attaaattgt ccatttcggc gccagaaatc gattctggac
    25321 cagtcttgtc tacatggatc attttttgga tcgcttttaa cgttttaagg ttctcaggag
    25381 acgcaaattc agacttagta taatcatcgt tcactaattt accgccattt gctaacatcc
    25441 agttatataa cggtgcagtt ccatccttat tgaagacaaa acctgataca tttttactac
    25501 tatcagttaa ttttggtgcc atttctgtca attcttccca agtagtaggt ggttgttcag
    25561 tatctaatcc agcttgttta aacaaatcat tattccaata catatacatg ccttgtacct
    25621 gcatggggac aaaatactgt ttaccttcta cttcacctaa ttcaatagcc gtttctttaa
    25681 aatcagattt atctactcca tcatattccc agaaatcgtc taatggttgt accgctccgt
    25741 tttctacata ctgtgcaaaa tctggataat ttaatgcaat aaagtcaggt gcttttttag
    25801 aagaaatcgc tgtaggaagt ttttcattca aattggccca agtcatgata tccatttcaa
    25861 ttttgatgtt tttatcattt gttttattaa attcattaac gatttcttgc aatatttcac
    25921 catcagatgc agtaaaccca ttccaaaaag tcaaagtcac ttctttatca gaatcagatt
    25981 ctgctgaact tccgccaccg caagctccta aaatacctgt tgcagctacc aacaaagagc
    26041 caattaacca ttttttacct ttcatttttt gttcctcctt catctgataa acgacatctg
    26101 accacattcc aagatagcgg tttcaataaa caattgattt tcccatcttc agcttttaca
    26161 tttgttgaat gacttggttt tacttgttca cttttaggaa gattagttgc ttttgtatca
    26221 aatccactca tttcagaaaa atcaatcact ccctctaatg ataattcaga caagtgaaca
    26281 gttagattca tttcttcttc tccacggtta actgcaaata tgacaagttc tttgtcattt
    26341 attacggcta tactttctaa atacggcact tcttcaaaat cttccgtcgc atagtttgct
    26401 gaacgaattt gtgggcttaa cacctctcct tgtccataca cagcagcttg cataaatgga
    26461 taatagatcg tctgtctcca agcttctccg tttgtttctg tcctgattgg tgcaataacg
    26521 tttaccaatt gagcaagaca agcaatcttt actctatctg catgtttcaa taaagtgatt
    26581 aatagacagc ctaatagtaa tgcatcttca aaattatagt tatcttctag taaaggagga
    26641 gcaatctgcc aaggcgctgc ttgctcatct tgttccgctg aatgatacca aatattccat
    26701 tcatcaaagg acaggttgat ctgcttctta ctatgtttct tcgccttgac tgtatcgcac
    26761 atcgctgtca cttcagaaat gaaccgatcc atgtctaagg aacgtgcaag ataatgagaa
    26821 agatcatttt tttggttgcc ataatattga tgcagagaca aataatctat ttgatcgtac
    26881 gcttgatcaa gaactgttaa ctcccaatca ccaaatgtag gcatttgccg attcgaactt
    26941 ccgcataaaa ccacctcaat tgaatcatct acgagtttca tcgccttagc cgtttcctct
    27001 gctaaccgtc catattcttc cgctgtttta tgtccaatct gccaaggacc gtccatttca
    27061 ttccctaaac accatgtctt aattccaaaa gggctctctt gaccattcga acgccttaaa
    27121 tcactccaat aagttccttt aggaaaatta caatattcga ctaaattacg agctgcatct
    27181 actccacgag tacccagatt gacagccata ttgatttcgg cccccacatg ctgacaccag
    27241 ttataaaatt catgaatccc aacttcattc gtttcaattg tccgccaagc taaatccaac
    27301 cttctaggtc tatttgctat gggcccaata ctgtcttccc aacgaaatcc tgacacaaaa
    27361 tttccaccag gatatctaat catgggaatg ttcaattctt ttaccaagtg aatgacgtct
    27421 tggcgaaatc cacttttatt agctgatgga tgatctggct gataaatccc ttcatatact
    27481 gctcgtccca tatgttcaat aaatgaactg tacaaccgcg gatcaacttt gcctacacgc
    27541 ttgacactac taatcaacat tgtggcttcc ataactgacc tcctttaatt tatacatgaa
    27601 taatacacct cgttgaaagc gttgtcaata atataaatgt taaacttact tattttttat
    27661 cgattttaat taaccaaaat attaataatg attaaaacaa ataatttaat ataactttta
    27721 ttaacaaata tgttaatata taagaaaaac cttttaagag gtgatatata tgcaactaca
    27781 aataaacgaa gaatccttac cggtatatga agcattagct agtaaaacaa ggatcaagat
    27841 catccagcta ctttccaaaa aaaagatgaa tgtcaaagat ttggcaaaag aacttggagt
    27901 gagcagtgct atcacgacga tgcacgtgaa aaagctagag gaagcaaaca tcatcaaaac
    27961 agaaaaagta ggacaacaaa aaatttcgag ccttcgtgtc gataaaatcg atattagttt
    28021 tccagaaaaa atattcaatg cttttgatac gaaagaaaca tcgataccta ttggtcacta
    28081 tacaaattat gcaattgaac caacatgcgg tttagctacg atccatgatt ttatcgggaa
    28141 agtggatgaa ccacgctatt ttatggatcc tcgaaggatg gatgcccgca ttctctggtt
    28201 taccagcgga tttgtcgagt atcaggcacc taatttttta aatacagagg atacattgga
    28261 gatgttggaa gtttctgtgg aaatttcttc tgaatttcct ttttcaaatg acaattggcc
    28321 ttcagatatc actttcagcc taaatggtgt ggagctagga acatggacga gccctggaga
    28381 ttttgctgat atccgcggta aatatacgcc tgattggtat ccagataatc ttaatcaata
    28441 cggcttgctg aagacgatcc gaattaccaa acacttgacg aatatgaatg gagaaccctt
    28501 gtcaaacatc acgatcaacg acatccctaa agagcaagac acttggcatt tgcgaatcga
    28561 agtgaaagac gatgccaaac atgtgggggg ctgtacttta tttggtaaag gattcggtaa
    28621 ttacgatcag gatatcaaat taaaagttta ctacagctga tatttttctt ttctatttta
    28681 taaaacaaaa acagccaatc cctatgaagg gacggctgtt tttgctttat tgttatttcc
    28741 agaaatcatc caaaacggaa attggcaaat gtcgtttatg ttgtgtcttg ttccaccatg
    28801 cttcgatttt ttcttgtgct tgagcgggaa cttcttttcc ttctagataa tcatcaattt
    28861 cattatatgt gacacctagt gcgacttcat ctgcaatcat tggtttccca tcttcaagat
    28921 ctgcagtcgg aatttttgtg tataattttt ccggtgcatt caatgcttga agcaattgtt
    28981 tcccttgtcg tttgtccaaa cggaataatg gcaaaatgtc ggctccacca tcaccaaatt
    29041 tcgtgaagaa tccagtaatg ttttctgcag catgatctgt ccctaatacg gctcctgctc
    29101 tttctccagc tacggcatat tgcgtaatca tacgttgacg tgctttgata tttcctttgt
    29161 taaaatcgct gattcccaca cctgcttcgc ttaatacttg tacttgtgca tcaacagctg
    29221 gtttgatatt tactcgcaga ctaacatcgg gctggataaa gtcaagagca gcttttgcat
    29281 cttcttcatc tgcttgttca ccataaggaa gacgaacagc gataaattga tagttttcat
    29341 cttttgtttc ttcacgcatt tcttccatcg ttagttgcgc caaacggcct gctaaagtag
    29401 aatcttggcc gccgctgata cctagtacaa aagttttaag aaacggatat tttttcaaat
    29461 atgctttcat aaagtcaata cttttacgta tttcttcttt tggatcaatt gttggtttga
    29521 cacctaattc attgataatt tctgtctgca ggctcattta ttctcctcct atgcttctgt
    29581 atgaagttct gctacgcttt ttttcattcg ttccatgata gccattttat ggttccagca
    29641 ttcagtagac agatcgactg ggtatttttg cggattcaag tctcgtttat actcttccca
    29701 tagtgaatct agattttctt ttgtatattc tttgatttcg tttagtgcag gtaattcgta
    29761 aactcttttt ccttcgataa agatatcttg taaaactggg cgagctgtaa agtctcgaac
    29821 agttttattg ataaacgtat gcactggatg gaacatgaag atagcttctt cttctcgagg
    29881 gtcttcatcc cataatgtca cgtagtctcc ttcagatttc ccatcaaaat ttcgagtgat
    29941 gcgccacact tgttttttcc ctggagtagt tactttttct gcattgcttg ataacttgat
    30001 cgtatccatc atttttcctt catcatcttc gatcgatact agcttgaata ctgcaccaag
    30061 ggctggctga tcataggctg tgatcaattt tgtcccaaca ccccatacat caattttagc
    30121 tttttgcatc tttaaattca aaatcgttgc ttcatccaag tcattcgaag catagatttt
    30181 tgcttccgta aatccggctg catctaattg ttcccgaaca cgcttagata tataggccat
    30241 atctccactg tcgatgcgta cgccttggaa gttgattttg tcacctaatt ctttcgccac
    30301 gcgaatcgca cttggcacac ctgatttcaa cgtatcataa gtgtcgacta agaacacgca
    30361 gtctttatgg gttttagcgt aggccataaa tgcttcataa tcatttccat aagattggac
    30421 taacgaatga gcatgggtcc cgctagctgg tatcccaaat atcttcccag cacgtacatt
    30481 gcttgttgca tctgctccgc cgatatatgc cgctctagtt ccccagactg ctgcatccag
    30541 ttcttgtgcc cgtctagttc caaattccaa tagtggatct tctccgatga cagatttgat
    30601 acgagctgct tttgtcgcga tcaacgtttg gaaattgacc atattcaaca gtgctgtttc
    30661 tactaattgg cagtgcgcta aaggcccttc cacttggatc aatggttcat ttgcaaaaac
    30721 tagttctcct tcacgagcag aacgaactgt tgctttaaat tcaaaatttt gtaaatactc
    30781 caaaaaacct tcaggataga cttctaatcc acgcaagtaa gcaatatcgg aatcattgaa
    30841 cgtcagattc tctaaataat tgactaaccg ttccaatcct gcaaaaaccg cgtatccgtg
    30901 gttaaaaggc atttctcgaa agtaacattc aaaaacagca tgtaaatcag ctcgacctaa
    30961 ttcccagtat gtctgcatca tattgatttg atatagatcc gtatgcagcg tcaaactgtc
    31021 gtctgggtaa gtattattca tcttgtatta ctcctcttgg caagttttca tttcctaccc
    31081 attataacaa aaaaaattaa taggaaaaga aatcttccat tttttctgaa aaagcacatg
    31141 ttttacggat atttcttgct aaaaatgaac tccatctgct aaaactatcc tttcttattg
    31201 gtatttaacc taaacgagaa agaatactta ttttattcaa tgtatccgag acacgaagaa
    31261 attagcgttt tctatttttc ttacttgata aaataagtag attttcctac tacaatcgta
    31321 gccgttaaga taccgatgat tgaacaaata taaccaaatg tctctacaac ataatcaatg
    31381 gcaaaagttt ttgaagcaat aatacgtctt tccttttttg cttcttatcc ccaaagaaac
    31441 ggatataact tattatgtat tgaatttttt tggaaaggcg aattatgaca agatatacct
    31501 tgcgttgaaa aaactcgcgg aaaaaatatc acacgttttt aaaaagatac aaagtaagaa
    31561 agcagctgtc aatagaatgg aaacaaaaat ggcgagacat caatcagtct cgccttgttt
    31621 tttattgtat acattagata tggagcaggt taccataaag atgattatta gtcgttatta
    31681 aatagaatcc ttcgtatttt tttgttctat cactacaata tctttatttg gacgtttgaa
    31741 ttgtattccg gcacgttcta gctcctgttt cactcctaca tggactttga catcttctcg
    31801 tgtcattttt aaaacgtgat gaatcgcata gtcgatttct tgccttgtga tttttttctt
    31861 cgtattgatc atcacgactt gctttttatc atatgtgtct accaatagca gttgtgttcg
    31921 atctaacgaa aataatttgt aataattaat agccgtattc ccaaaaaaga attccactac
    31981 tttaggataa aatgtcttaa tatttaaatt actattcaca ggtgtttcga ttagcttcat
    32041 ctcattcctc ttttctatat agtcgattta gatccaatct taagttatgt taccatcttt
    32101 cctagcatta aggaatcggt tacaattgaa cctttaaaga caaaaggatt taccttttat
    32161 cacttaatag tataacataa tttcatgaga aaaaaataca attttttctt gaccatctcg
    32221 ttacgtaaag gattatgctt acatttgtca ggaggaaaaa taatggagta cacaataaag
    32281 aaaatgtcag agatatcagg agtcagtccg agaaccttgc gcttttatga tgagattgga
    32341 ctgctaaaac cagctaggat caattcttca ggttatcgga tttatggcaa aaaagaagtc
    32401 gatcgtctgc aacacatctt attttatcga acaatggcat tcaagttgga tgatatccaa
    32461 gaggtcttag acaatccatc ttttgaccac cagaaagctt taatcaagca tcagcaaatg
    32521 ttgctggaaa aacgggcaca aatcgatacc ctcttgacaa ctgtccaaca gacacttgat
    32581 atgtacgaag gaggaagaaa aatgagtgac aaagaaaaat ttgaagggtt taaacaacaa
    32641 aagttgaaag aaaatgaaga atcctatgga caagagattc gacaaaaata cggaaaaaaa
    32701 aaggttacag catccaatga aaaatggatg aatatggata aagaaacgta tgaagaaatg
    32761 caaactgttg aaaagcagat gttatttgat ctcactcttt acttaaaaga accagaagat
    32821 gaaagcttag cagaccgtat cttccaagct cataagaagt ggttatctta cagctggcct
    32881 gaatatcagc caaaagcgca taaaggacta ggaatgatgt acgaagccga tgaacggttc
    32941 actgcatatt atgacgagcg aagtggtcat ggtgcagcaa aagctttaaa tgaaattatc
    33001 caaaaaaagg cgtaatcttt tacatgatcc aacaaaaaag tacacgtaaa atgacctaat
    33061 aacaaaacag cagacaccca agttagattt ttatgctaac ttttggtgtc tgctccattc
    33121 tttcacaagt tttttcatcc tactttaaat atattcatcg ttgaataaac gtataaggta
    33181 ttttcacttt atcctttttt tctgtaagaa acaattgaaa tgccatttct ccgcaagctt
    33241 ccagatggtg gtcgatggtt gggaaaccaa gaagctcgct gatcagcaaa ttatcgcgtc
    33301 caatcaccac tggtgtctta tcttgcagat agctttgcaa gatgcctgct gcaaccatat
    33361 ccgaatttgt aaagacacca tcaactccaa gctctttaaa aaagaagcct gcttgttttc
    33421 ctttctctgc atctatacaa tcccaaaaaa caagtgattc atcaaaagat ggaaaaagtt
    33481 gatgacatag ctgcaaagtg atttttgagt tataacttag cctgccactt cgccccaacg
    33541 tgatgcccaa ttgctttata ccttgctgct tcaaataagt aagaccttct gtaattgatt
    33601 gttctcgatc aataaagaca cagcttgcct gttttccctt gatttcttca caaaaaacta
    33661 gaggtccata tttttgatat gccaataaat catctagtgt attggcacga gacgtaatga
    33721 tcaatccatc gaaagcttta gctgcaaatt cttcaagata ccttcgctct ttttctttct
    33781 gatagcccgt cggtaaaagt gtcactttgt aatcataatc aaacgctgct tcaatgatcc
    33841 cactgatcaa ctgatcaaaa tacggatgat tggtataagg cagaatcact ccaatgcttt
    33901 tcgtttttcc ataacttaac tgtctggcat ttgcattagg gatataatcg acttctttca
    33961 tgaccgcaag tatttctttc cttttttcct catctacata tggatgtcca ttgattacac
    34021 gtgaaatagt agaaactgaa taacctgtga gctttgcgat atctcgaatg tttgccactg
    34081 ctgcttcgcc acctatacaa aaagattttc ttgtaaatag tctaccacag ctggaccgca
    34141 ttcaaaaaac tgatacattt ttccttcatg cgaaaaactg atccgctgcc cgccccaata
    34201 tatatctttt gtcaaatttt cgatttcatt cattggtatt tcttttacta tattcctatt
    34261 caacccttga aaactgtaca acgttaatac ggatcccttg aactcgacaa acgcataaaa
    34321 ataattgttc gttgtgccat ctgttatctc tacataagta ttcattgcaa gccctccttt
    34381 tgatactttg agtatagtgt atgaaacgcg tctcatagca aggagtttgt tttgccaaag
    34441 aaaagtttta ttcctctttc attattacca aagtctctta ttttaaattg aatacattat
    34501 aatgatactg taaatatatc tttattatta gtgaatggat atttactttt aatagataaa
    34561 atattataac tattaaaaat aactattttc attataatta caca
//
LOCUS       DADQCX010000021        34119 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.021, whole genome shotgun sequence.
ACCESSION   DADQCX010000021 DADQCX010000000
VERSION     DADQCX010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.021"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..125)
                     /locus_tag="J8R83_000947"
     CDS             complement(<1..125)
                     /locus_tag="J8R83_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein"
                     /protein_id="HAZ9574091.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKL"
     gene            complement(216..668)
                     /locus_tag="J8R83_000948"
     CDS             complement(216..668)
                     /locus_tag="J8R83_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAZ9574092.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(681..1091)
                     /locus_tag="J8R83_000949"
     CDS             complement(681..1091)
                     /locus_tag="J8R83_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574093.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1366..1578
                     /locus_tag="J8R83_000950"
     CDS             1366..1578
                     /locus_tag="J8R83_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574094.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1581..1793
                     /locus_tag="J8R83_000951"
     CDS             1581..1793
                     /locus_tag="J8R83_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574095.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(2085..2309)
                     /locus_tag="J8R83_000952"
     CDS             complement(2085..2309)
                     /locus_tag="J8R83_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAZ9574096.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2387..2575
                     /locus_tag="J8R83_000953"
     CDS             2387..2575
                     /locus_tag="J8R83_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574097.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2901..3236
                     /locus_tag="J8R83_000954"
     CDS             2901..3236
                     /locus_tag="J8R83_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574098.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3469..4410
                     /locus_tag="J8R83_000955"
     CDS             3469..4410
                     /locus_tag="J8R83_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAZ9574099.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4412..5302
                     /locus_tag="J8R83_000956"
     CDS             4412..5302
                     /locus_tag="J8R83_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAZ9574100.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5345..6145
                     /locus_tag="J8R83_000957"
     CDS             5345..6145
                     /locus_tag="J8R83_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAZ9574101.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6160..7011
                     /locus_tag="J8R83_000958"
     CDS             6160..7011
                     /locus_tag="J8R83_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9574102.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            7008..7367
                     /locus_tag="J8R83_000959"
     CDS             7008..7367
                     /locus_tag="J8R83_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAZ9574103.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            7382..7543
                     /locus_tag="J8R83_000960"
     CDS             7382..7543
                     /locus_tag="J8R83_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAZ9574104.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            7540..7866
                     /locus_tag="J8R83_000961"
     CDS             7540..7866
                     /locus_tag="J8R83_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574105.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLEKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            7863..8678
                     /locus_tag="J8R83_000962"
     CDS             7863..8678
                     /locus_tag="J8R83_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HAZ9574106.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            8817..9128
                     /locus_tag="J8R83_000963"
     CDS             8817..9128
                     /locus_tag="J8R83_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574107.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNIQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            9125..9517
                     /locus_tag="J8R83_000964"
     CDS             9125..9517
                     /locus_tag="J8R83_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574108.1"
                     /translation="MIPRFRAWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVGIFDGDIVLVNVSNGFDHLVNEKTIVQESGFHSGLICKSLASGMEYRV
                     FKHKKMDYEYEVIGNIYENSELLEDSDE"
     gene            9642..10094
                     /locus_tag="J8R83_000965"
     CDS             9642..10094
                     /locus_tag="J8R83_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAZ9574109.1"
                     /translation="MIDMMDEPQKLVVPKFVAEWFEENKDDLEFAIWELCVDSYGSTE
                     QGMLNWIQRSENNPIETLIRMKDGYEVEKEPLYYVRLPYEFWDEEAAELKTEYVYLHH
                     EITSDETRIYPIKEPRKGFSTKLDEITIKSIDERFWPFAVPVEEVAEG"
     gene            10163..10357
                     /locus_tag="J8R83_000966"
     CDS             10163..10357
                     /locus_tag="J8R83_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574110.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVMINAQGYDNGFFKRITDISIQQ
                     GMVDDDGNFIDEVAILVTCE"
     gene            10388..10585
                     /locus_tag="J8R83_000967"
     CDS             10388..10585
                     /locus_tag="J8R83_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574111.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEDE"
     gene            10582..10887
                     /locus_tag="J8R83_000968"
     CDS             10582..10887
                     /locus_tag="J8R83_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574112.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNGIKN"
     gene            10871..11164
                     /locus_tag="J8R83_000969"
     CDS             10871..11164
                     /locus_tag="J8R83_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574113.1"
                     /translation="MELKIDKVTFEEPAFQEMDERIAELVEKKQDELIALLEKKYQFP
                     KYMNKMQAAKYLGVSYNTMMDKYVPAGLKMGIVNGVIRISKEECDRFMKEHQK"
     gene            11424..11837
                     /locus_tag="J8R83_000970"
     CDS             11424..11837
                     /locus_tag="J8R83_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAZ9574114.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKYGNKAEDAIIQMMDIEAERDAILVALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            11850..12236
                     /locus_tag="J8R83_000971"
     CDS             11850..12236
                     /locus_tag="J8R83_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574115.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            12787..13011
                     /locus_tag="J8R83_000972"
     CDS             12787..13011
                     /locus_tag="J8R83_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574116.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            13029..13457
                     /locus_tag="J8R83_000973"
     CDS             13029..13457
                     /locus_tag="J8R83_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574117.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            13435..14853
                     /gene="terL"
                     /locus_tag="J8R83_000974"
     CDS             13435..14853
                     /gene="terL"
                     /locus_tag="J8R83_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HAZ9574118.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            14865..16400
                     /locus_tag="J8R83_000975"
     CDS             14865..16400
                     /locus_tag="J8R83_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9574119.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            16480..17358
                     /locus_tag="J8R83_000976"
     CDS             16480..17358
                     /locus_tag="J8R83_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAZ9574120.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            17360..17677
                     /locus_tag="J8R83_000977"
     CDS             17360..17677
                     /locus_tag="J8R83_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574121.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            17726..18427
                     /locus_tag="J8R83_000978"
     CDS             17726..18427
                     /locus_tag="J8R83_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAZ9574122.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMIMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETF
                     TNPEEQLGQILQQFN"
     gene            18442..19332
                     /locus_tag="J8R83_000979"
     CDS             18442..19332
                     /locus_tag="J8R83_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAZ9574123.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEQANST
                     EIKWREYDINNDDSSEKLEGGDYPDAESGRNWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDGLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            19355..19570
                     /locus_tag="J8R83_000980"
     CDS             19355..19570
                     /locus_tag="J8R83_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574124.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            19582..19923
                     /locus_tag="J8R83_000981"
     CDS             19582..19923
                     /locus_tag="J8R83_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574125.1"
                     /translation="MDESLKTEIIESIKEDFPDLSEERITNLLEIILLEIESYNSCKN
                     DVSWEKLKSVISEVLYQIIKNESEKKVSSVRRGDTTISYASTANAVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            19923..20294
                     /locus_tag="J8R83_000982"
     CDS             19923..20294
                     /locus_tag="J8R83_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574126.1"
                     /translation="MNEADILETTYEDSCIIERLMDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            20287..20682
                     /locus_tag="J8R83_000983"
     CDS             20287..20682
                     /locus_tag="J8R83_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAZ9574127.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            20684..21061
                     /locus_tag="J8R83_000984"
     CDS             20684..21061
                     /locus_tag="J8R83_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574128.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            21062..21670
                     /locus_tag="J8R83_000985"
     CDS             21062..21670
                     /locus_tag="J8R83_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9574129.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            21670..22011
                     /locus_tag="J8R83_000986"
     CDS             21670..22011
                     /locus_tag="J8R83_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574130.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            22253..25042
                     /locus_tag="J8R83_000987"
     CDS             22253..25042
                     /locus_tag="J8R83_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAZ9574131.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVASSMESFLKVIAANIPRAVSFLSNLFDAVQKFGSALKFMMPFLVPA
                     TTAFGALMFQLKGIPTIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIVGAVVGAI
                     AVFGYFMATNEEVRNKVISVWNDVKDSVLGVLKNIKDWGIDTWNSAKEMASNAVESVK
                     DAWSGIKEWFSNTWQGIKNGATGLFDKTVETSMNAVDSVKNAWSNTKQWFSDIWQSIK
                     DSATEKWNEIKGSIMEVAGPLITGLKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LTPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            25032..25772
                     /locus_tag="J8R83_000988"
     CDS             25032..25772
                     /locus_tag="J8R83_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9574132.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            25769..28531
                     /locus_tag="J8R83_000989"
     CDS             25769..28531
                     /locus_tag="J8R83_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAZ9574133.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            28544..29452
                     /locus_tag="J8R83_000990"
     CDS             28544..29452
                     /locus_tag="J8R83_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAZ9574134.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            29452..30072
                     /locus_tag="J8R83_000991"
     CDS             29452..30072
                     /locus_tag="J8R83_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574135.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            30076..30525
                     /locus_tag="J8R83_000992"
     CDS             30076..30525
                     /locus_tag="J8R83_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574136.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            30525..31019
                     /locus_tag="J8R83_000993"
     CDS             30525..31019
                     /locus_tag="J8R83_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574137.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            31033..31464
                     /locus_tag="J8R83_000994"
     CDS             31033..31464
                     /locus_tag="J8R83_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574138.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            31466..31603
                     /locus_tag="J8R83_000995"
     CDS             31466..31603
                     /locus_tag="J8R83_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAZ9574139.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            31641..31934
                     /locus_tag="J8R83_000996"
     CDS             31641..31934
                     /locus_tag="J8R83_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574140.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            31931..32155
                     /locus_tag="J8R83_000997"
     CDS             31931..32155
                     /locus_tag="J8R83_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAZ9574141.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            32152..33177
                     /locus_tag="J8R83_000998"
     CDS             32152..33177
                     /locus_tag="J8R83_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9574142.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            33367..33440
                     /locus_tag="J8R83_000999"
     tRNA            33367..33440
                     /locus_tag="J8R83_000999"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33401..33403,aa:Ile,seq:cat)
BASE COUNT        12159 a         5024 c         7274 g         9662 t
ORIGIN      
        1 tgtaatttat ttagtttttc atcatttttt tgttctaatt cataagcttc tttttttatt
       61 gtgttagctt tcgacagttt agtgattcct ataattaata aaataagtcc aatcaataat
      121 aacattcaaa actcctcatt tctttgatat aattattgta gagtttactc agaaatgagg
      181 aaagagtcca tgtgaaagca tgggcttttt tatttttaat gttgtaatac taaatgttca
      241 agattatgag gaagccctaa atattcaata atttggaact gactcatatc agataaatct
      301 tgttcatcta ttgttctagt taacatttca attgcaaaca tattagcttc agcttctata
      361 ccataaatca tacaactaag gttgtttgct ctaaaagctg ctgtgcaaat acctttatgg
      421 agtctaacgt gggctatttc atgccataat acaaatcttt tcatagaagg tgataggttt
      481 tgattaatta atatcacata acatctttta ttgtgtatcg tttgtcctaa tgttttattc
      541 cctaaatcag tttcaattaa atctatatca gaatatttga ttattttata tggattaatc
      601 gcatcagatc caaactctac aaataatttt tctatttctt ctaatatcca gtatttgttt
      661 aaatgcatac caaagcccac ctattgacga tattttttag gagtgaattt tttctttgct
      721 ttaactttgg ttaaggcaag tgcaagttga atggcatcgt ataatttttc cttatcttca
      781 tcgtctaaag gttcaccata ataatttgtt tcagcatctg aattcaagcc ttcaagtaat
      841 ttttcagctt gtaaagcaat atcttgttta tctttttctg ttaaatcata ataatggcgt
      901 ttatcagtac gtcctaaaag ataatcagtt gatacattaa agtaatctgc aactttttgt
      961 attttatctc cagatggagt acttttattc catctagaca tgcttccatt tccgaaattt
     1021 aactttcttt caagttctgc caacgtcatt gaacgttctt ttaataagat ttttatacgg
     1081 tctaatagca taggatatgc attcctttca aaataccgac aaaaaaagta tttttctgca
     1141 aattatctat ttacaaatag agaatttgca gttatactag ttttgtaagc aagatattta
     1201 cggcatacaa agactaaaag caataaacta atagtctccc cagacatcag taagctcgct
     1261 ttttgtgcgc tgtattttgt atgcttacat aatagcatat ttgcagtttt tgtcaaactt
     1321 attagacaaa aatattagaa aatattcgat aagggggtat gaagcatgac tttaaaacag
     1381 caagtattaa ttgctttagt aaagaaaggt tggagtcaaa gagagttagc tcgacgaatg
     1441 ggtatatcaa ttacttattt acgagatatc ttcatcgaaa aaagaaaacc taaggaacgt
     1501 ttaaaacaaa tcgaagaact tttggatatc aagttagaag tagattctaa tgatcagcca
     1561 tcagaacagg aggcgtaaaa atggtacaac gtttgagcaa agcggagttt aaagagaaat
     1621 ataagtattc tgaaagtact tatcaaagaa gaatgaagga atttaaaaaa tcacgtttta
     1681 gtgaggggta taacgcagtt acttccaaag aaataacaat tgatgtcgat ttatatgaac
     1741 agtttagaac atggcgttct aaaaatcgat ttagagttag agctgtttgt taatagctaa
     1801 aaaatctaaa ttcaccactt ctgaaaagag gagttgctgc tctcctttca agtttgccaa
     1861 agtccacgtt ttttcatttt ggcaactcct cttcttggag gtggtgacgg cgagagacga
     1921 aggagggatg acatgaagga agaatcaaaa atagggattt tgaatgagaa caattacaca
     1981 agattaatta ttgaaacaga agaagggaaa aaagtagcag aagttacatt gaccgatgca
     2041 actcctgctg acggttatcg tattcgatta actcctaaat atgattaacc ttttggtggg
     2101 tgtggatcgt ttccgtgact atcacggctt tgaatttttc catctctgcc atgaataaat
     2161 agctcagatc cttgattttt agaaatctct ctagcgattt ttactgcttc tgattttgta
     2221 ttagtatgtg cagtcgcttt agaatttcca gcacctttga cattccaacc accattggaa
     2281 ttaggtacaa catgttgatt ttttcccata gttttcacct ccatttctat agaaatattt
     2341 tatcaaatag aaatggagaa attcaataaa cgaaaggaga agtgatatgg catatacctt
     2401 gcaacaagaa catcaaattc tcggtttgat taaacaacgc aggaaacaat tacaagatga
     2461 ccgtgcagcg cttagaaaag ccgatgagct atcagatagg caagctgaac taattgcttc
     2521 tgaacttgag gatttgagaa tgctagaaat aaaaaatagg gagattagat tatgaagaag
     2581 acagacacac tttttatagg attcattttg gggttattag tgattgtagc gcaccaaagt
     2641 attatcgggg gaagcttgtt cgcagcattg atggttttaa tcaatctgct tgattcaaaa
     2701 gaaaggagca actatggcac gagaagaagc gctaaaaatc ggtaaagtga ttgctgataa
     2761 tcggtgggga aatagccgcc ctattatttt aagcaagcaa catatcgaaa agcaaaaagc
     2821 atggcaacaa ataaaaaagt gactctgcca gccagcaaag agtcacatac aaatttataa
     2881 aactaggaga attatatcac atgaataaga aaattgaaaa tcttatcgaa gaattgaaac
     2941 gtgaatgcca aaagcaaggt gtttctatta tttgtacagc ccaaaaagaa ggggaactta
     3001 aaagtctcgt ttatggtgag acaacagaaa ttttactttg tcttgctatg caagaagaac
     3061 atttagatga aaatctccca ttgtcagcac atattatgcg tagaattgct gtggatgctt
     3121 acgaacaagc gaaaaatgaa gaagaaaatc aaccttcaaa tcatactttt gttattaata
     3181 acaaggaaga tttagctgat gtgatgactc gtattctcaa gggggaattt caatgatgaa
     3241 tgaaaaaaca attgatctac tcattatttt atttttcacg ttagtgattg tagcgaaaag
     3301 ttatgtaatc tttggcttgt tattcgcaat taccatgctt gtgctttgcg tgttagcaag
     3361 cagaaaagag gttaaacatg aacgagttag caaatcttga caactattta actgatcctg
     3421 attatgctaa accaccatat gaagcaccaa ttgatgagga ggatgaagat gagtaaatct
     3481 accttagaaa tgagccatca agaatggctt gaagaccgta agaaaggcat cggaggttcg
     3541 gatgttggaa caattttagg attgaataaa tggaaatctc cttatcaact atggctagaa
     3601 aaaacaggac aagtagtact tgaagaatca ggaagtgagc ccgcttattg gggtaatgtt
     3661 ttagaagaag tggttgctaa agagtttcag gaacgtacag gcaaaaaagt acgcagaaga
     3721 aaccaagtat ttgaacatcc attacatcca tttttaagag caaatattga tcgggaagta
     3781 gtgggagaaa atgccattct ggaatgcaaa acagccaatc aatttctcgg taaagaatgg
     3841 gaaggcgaag aggtaccgct tagctatctc tgtcaagttc aacattacat gaacgttcta
     3901 aacaaagact attgttacat cgctgtctta atcggtggtc aaaaatttat ctggaagcgg
     3961 attgaacgag atcaagagct gatcgataca atcactgaac aattagtaga gttttgggaa
     4021 acaaacgttc ttggaggtat cgagccaatt attgatggta gtcaagcgac agctgatttc
     4081 ttgaaagaga agtatgcaga tgttgaagac gttcaaacga cgttaccaat tcatttcgat
     4141 gaactagttg aacagaaaaa cgaactcaaa cggactaaga aagaaattga atcagctatc
     4201 cgtcaagtag acaacgagat tatcagcgag ctaggtaaac gtgaagccag tatcggtatc
     4261 actcaaaaaa acatcatcag ttggaaattt gtccgtacga gacgtatgaa ctcgaagaaa
     4321 ctagcagaga aatatccaga tgtcgcaaat gatgaagaga tttataacgt tactgaatca
     4381 agaaggctaa ccgaaaggga gatcaaataa tatggcaaca aatgaatcgt taaaaaatca
     4441 attggcagca aagccacaga aacaagttgc accaggtcaa ttaggactta aagctttgat
     4501 gaatacacca acaatgagaa agaagttcga agaggtgctt catgacaatg ctaatgcttt
     4561 tatgtcgaat gttatgactc ttgtatctaa tgacagttat cttgcagata gtgaaccgat
     4621 gtctatcatg agtggtgcgt taactgctgc aacattaaat cttgggctag ataagaattt
     4681 aggttatgca tatttagttc cattcaatag taaaaacaag caaacaggaa aatgggaaaa
     4741 gaaagctcaa ttcatgcttg gctataaagg atatatccaa ttagcccaac gatcaggtaa
     4801 atacaaagca ttaaatgtga tcgaagttta cgaaggagaa ctaaaaagct ggaaccgact
     4861 gacagaagag tttgagtttg atccaaatgg tagaacgtct gatgaagtca ttggatatgt
     4921 tggctatttc gagttactga atggattcaa aaaaactgtc tattggacca aacaagaaat
     4981 cgaagctcat cggattgcta acaataaaga tcgcgataag acaaagttaa gtggtgtgtg
     5041 ggcatctgat tacaatgcaa tggcacgaaa aactgttttg agaaatcttc tttctaaatg
     5101 gggaatcttg tccatcgaaa tgcaagaagc caccacatcg gatgagagag tccaaagggt
     5161 tcaagaagac ggcagcatta ttgctgaaac agaagttgaa gaagatattc ctgaaagaaa
     5221 agaagcagag gttatatctg aagaaaatga agatgtacaa actggattat ttgatgcatc
     5281 taatccgccg ttaaacaaat aatgagggag ctttctccct tgcttttcta gaggagaaat
     5341 acgaatgaac acaggatatg tcaaattaca tcgaaaagtg atgaattcat tcgtttggac
     5401 caatccttat atgtataaat tatggaactt gtgtttgatg aaagcgagtc atgagaatcg
     5461 caagatactt tttaatggaa aagagataca agtgaacagc ggagaattcg tcacagggcg
     5521 cgatgctatc acatctgaga tgaacgaagg cgtgaaacgt gaacatcaag tgaacagcgg
     5581 ttctgtatgg agatggctaa aacaatttga aaaaaacgga atgttgaaca tcaaatcaac
     5641 tacgaaatac agcgttatat caataaaaaa ctggtctttg taccaaagca gtgaacaaca
     5701 aatgaacatc aaacgcacaa caagtgaaca acaagtgcac acaaacaaga atgaaaagaa
     5761 ttataagaat gaaaagaata ataaaacatc atcgtcgcaa ccacgcaaaa agcgtgttta
     5821 cgacaccgac tcagtttact acattctcgc ggaggagtta ttcaaacaga tttgtcagaa
     5881 tcaggaaatc aaaaagccga atctgcaaag ttgggcagat aacattcgga aaatgatcga
     5941 gatcgacaag cggaccgaaa accaggtacg gggaatgatt gaatggagtc agcacaatgt
     6001 gttttgggca tcgaatattt tatctgctaa aaaattgcga gaaaaatacg acacaatggc
     6061 agcgcaagca aatcgtgatt ataaaacaaa acaaactaaa acgcttgaat acgagaaatt
     6121 tagcacagat gagttgccta tttgagagga ggcgtaggca tggaaactgt tggggaaatc
     6181 atggaaaagc tgatacagaa agtgcttgtc caacgtggcg aatgtcctga atgcggacag
     6241 cctttgtatg gatggcgtac gaagaaccct gatggctcag aacgttgtaa gccaacctgt
     6301 atgcaatgtg ggtataaagc attgcgagtt caggaagact tacaaacaga acgaatttac
     6361 aacgagagcc tgaaagcaag agcaatcaat tttttcaaag gtggttctgt tgtgcctaat
     6421 caagcgttgt ttgattgcac attgcagaat tatcaaattg tcgatcaaga aacaagacaa
     6481 gcggttgaag taaccaaacg ctttgttaat tcagtcttgt taggaaatcc aagtcacctt
     6541 gttttaactg gaaaacaagg aacaggtaaa agtcacctag cgatggcagc ggcttgggaa
     6601 gtcttgaagc gatcaaacta cgataaaaaa atcttattta tcgggttaca ggaaatgctg
     6661 gatcaaatca aattttcgta caacaatcct gaactcagaa aaacgattga gggatcgttg
     6721 attgcagata tcaaaacagc ggatttagtc atcattgatg atatcggttc agaactagga
     6781 aaagatgcat cagatagtcg agcgtttggc ataaacacgc taaattcgtt cttggatgca
     6841 cgacagaacc tagcaacgat tatcacaacg aacttgcttg gtgaagaact gaaaaaagct
     6901 tacggtacga gaacaatatc aagaatgttt gtcaactctg atggatttac gatggtattt
     6961 tctcaaacag cagacaagcg cataaaacca gtgaaaggta gtatcgcatg aataaatacc
     7021 gtaataaaaa aactgttcat cgaggtatca agtttgattc tatcgcggaa gcagagtatt
     7081 acgatctagc cttgtggcaa gctgaagcga atggttggaa agtgaagctc caggaaaggt
     7141 ttgagctgat gccgaagttt gaactagagg gcaagaagta tcgcaagatc gagtatattc
     7201 ccgacttcac attttacaaa agcggcaagc tggtcaaagt cgtagatgtt aaggggatgc
     7261 agacaaaaga ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga
     7321 tattagccaa aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat
     7381 catgacaaca gaagaagtga ttcaaatgcg aattcgaagc cttcggcgtg agattgacga
     7441 tctggaacga acaaaggcag tgatggtcaa tgaaacggct agaaaggcaa tcgatttgca
     7501 catagagaat ttaagaaggg aaatccgtag attggaggaa tgagcgtgga taaggaagcg
     7561 gcttggcgaa aattaatgtt gctgattcaa gatgagaact ggcaagaaga tgaagcagtg
     7621 gttgctgaag ttcagcgtct agaaaagatt gctaacggac gtatacgaaa aaagccagac
     7681 aaaagaaaac agcgcaaagg gaaaatcgtc gttgttttac acgaaggcaa aattttgatg
     7741 caaggaacag ctagtgagct gtctgcagaa actggatata cgcgtgggac tattcgaacg
     7801 tacgcttggc gaaatcacac cgatcgaaaa gggcacgaat ataagtattt ggaggaagaa
     7861 aaatgaacga aaacaaatta atcaaattgg gtgtagcagg agcagtaatc gtaggtattg
     7921 gagttatcgg aggatttaag ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct
     7981 attcaatgaa cggcggtatc aaagatgaag cactgacgca aggtgtgaaa tttgtaggga
     8041 ttgacaaagt gatccaatat ccaattcgct tgcaaactat ccaatcaaaa aatatttcag
     8101 tatctacaag cgacggcaaa aagacaacga ttgatatcaa atatgactac aaagttgatt
     8161 caactaaagc agcaaaaatg tacaaggaat ttgggaatat cacttcggaa gatatcgaaa
     8221 gtggatggtt aaaatctaag cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc
     8281 tgcttgatgt cctttcagga gattcctcta aagttgaagc tgaggtatta acgaactttg
     8341 ctaaatcagt tgaatctaaa gggtttgaag tcgaagacgt aacacttggt gttccagatg
     8401 tcgataaaga aacacaaaaa tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa
     8461 aagcgaagct agacgcagaa actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa
     8521 caaaagctgc agaagcagag gcagaatcta atcgcaaagt cgccgaatca gtaacagaca
     8581 atttgattcg ttatgaagaa gctcaagctc gcaaaaagca tggatgggta acagtaaatg
     8641 gagcagatac tgtagttacg gatgaagcag gcaaataata tgggattctt tatggctaaa
     8701 attctcttgt tcttaggttt agtaggagca gcatatctcg tgtatgcgct cctttcccaa
     8761 actgatgaca aagaagatga caacaacgat gaaatgaaat tttaggagga gaaataatgg
     8821 acgaactaat cacaaaagta gagcagtggg ctaaagacaa gggactggat caagcagatc
     8881 caaaagcaca gtttttgaaa gtagctgagg aattcgggga aatagcttca gcgatggcaa
     8941 gaagtaatga tgagctattt aaagatagcg taggagacgt tatcgtcacg ctgattatcc
     9001 tttccatgca aaaagggaca aacatacaag agtgtttaga aatggcatac aacgaaatca
     9061 aagggcgcac aggaaaaatg gtagatggtg tattcgtgaa gtcgagtgat ttggaggaca
     9121 gcaaatgata ccgagatttc gagcgtggta cacaccattt aaaggtaaaa caattggaca
     9181 agaaatgaaa tatgggcaag caggaaggtt gatcactcat gctgaaatgg ctccagataa
     9241 atatgtgctt atgcaatcca caggactgaa agacaagaac ggtgtgggga tatttgatgg
     9301 ggatatagtt ctggttaatg taagtaatgg ttttgatcat ttagttaatg aaaaaacgat
     9361 tgtacaagaa tccgggtttc attctggatt gatttgtaaa tcattagcta gtggaatgga
     9421 atatagagta ttcaaacaca aaaagatgga ttatgaatac gaagtcatcg gaaatatata
     9481 cgagaatagc gagttattgg aggacagcga tgaataaaca gggaccaaaa aataaactgt
     9541 gggcattgaa gcaaattgat gaggaaattg aagaagcacg tcttttaaaa tctgctgaat
     9601 acaacgaagg ttatgaagat ggctgccaat atagtcagcg agtgattgat atgatggacg
     9661 aaccacaaaa gctagtggta ccgaagtttg tggcggagtg gtttgaagag aataaagatg
     9721 atttagaatt tgccatttgg gaattgtgtg tagattctta tggttctact gagcaaggga
     9781 tgttgaattg gattcaacga tccgaaaaca atccaatcga aaccctcatc cgtatgaaag
     9841 acggctacga ggtcgagaaa gagccgttgt attatgtgag actaccatat gaattttggg
     9901 atgaagaggc agcggagctt aaaacagagt atgtgtatct acatcatgag ataacaagtg
     9961 atgaaactag aatatatcct ataaaagaac ctagaaaagg atttagtaca aaattagatg
    10021 aaatcacaat taaatcaatt gatgaaagat tctggccgtt tgctgtgcca gtggaagagg
    10081 tggcggaagg atgagtgaag atgaatactt tgaacagtag tctattaacg acagagattt
    10141 ccaactggaa aggggtgtag tcatggacgc atcggaagta gtaaataaaa ttaatagtct
    10201 caaagaggtt ttcggagacg tcgaagtaat gataaacgca caaggctatg acaacggatt
    10261 ttttaagcgg attactgaca ttagcattca gcaaggaatg gtagacgatg atggaaactt
    10321 tattgatgaa gtagccattt tagtgacttg cgagtaagta attgacagct aaagaggagg
    10381 aagagggatg aaagcataca caatcaagtt ttatggaaat aaaacctatg tatacatcct
    10441 aagcggtctc agacttgatt ttagaggcta ttcaaaagaa gaccttttag aatccttata
    10501 tggttacgga tatttaaatg aagatgaact aataagctta gagaaattta caaatgcttg
    10561 gacgattgag gaggaagacg aatgaaacta aaagacggat tttacgctag tagtcatggt
    10621 atcggcggtt taatgctaga tatgccgaca aagaacccta aaacacgtaa gaaaccaaaa
    10681 ttcaaagtcg gtgacatggt tcgatgtgaa gcagaagggt tcatctatcc atttcgtgga
    10741 tatgtagagc atctctataa tcactcagca atcattcgta ttgaaaacac gatggaatgc
    10801 gataagtggt tagcgaaaag caaagagaat ctagcagtgg cgagattggt ggatatggag
    10861 gttataaaca atggaattaa aaattgacaa ggtaacgttt gaagaaccag catttcaaga
    10921 aatggatgaa cgaattgcag aattggtcga gaaaaaacaa gatgaattga ttgctttgct
    10981 agaaaagaaa taccaatttc cgaaatatat gaacaaaatg caagcagcaa aatatcttgg
    11041 tgtaagttac aacacgatga tggataagta cgtaccagct ggtttgaaaa tgggtatcgt
    11101 taacggcgtt attcgtatca gcaaagaaga atgtgatcgt tttatgaaag aacatcaaaa
    11161 ataaaataaa aaaacgttta gccccttagc taaacgcaca attataattt acctgacagt
    11221 taattataac aaaattgcgg aggttgagga atggcggaat gaaaaagaca ataaaaacag
    11281 aagaagcata tattgaagta tttgacacac cagcatgcta agtcgagaag tgtaactcgg
    11341 caaataaaaa aagccggatc gctccgactg ttctaataaa ttccacaaat ttattatatc
    11401 acataaagga gcggtttgac ttgatgcaat tgttacgaga ggtagatttc aaacagacaa
    11461 gatgtaatgc gagagatgtg ctgaagaact ttcggcgttt ggagcggatg gcaggtcgct
    11521 ctttgataga tattaagtcg ccgattatta cggacatgcc aaaggcaccg aaatatggaa
    11581 acaaggcaga agacgcgatc attcagatga tggatataga agcggagaga gacgcgattc
    11641 tagtggcttt gatggctctt agtctgatta gtcgtcagat actctactac agtttttgtg
    11701 tgccagacag cttctcaaac tacagaatta gccgtgaagt gggttattca gaaagaagta
    11761 tacaacggat gaaatcggaa gctctaatag agtttgcaga agcatataaa cacggaagaa
    11821 taattgctta taaatagggg gaccatataa tgtggaaaga ttatgtatcg ttgaaagagt
    11881 tgaaaaaaga tcttgttttc aaaagaattg tagaatggtc agagagtgaa ttaattttag
    11941 aagatggaac caaaatggaa gttgtatgta gcgaatcaga ttgctgcgca tgggccgaag
    12001 gtgaattcaa aaatgtaaag cttgatgcag tgattacaga tataaagatt tttgataaag
    12061 gtaaccgtct ctataatggt gacggacata cctcttatgc tgaagtcgtt gtttatcata
    12121 atcgtaatga gatcgctaaa gcagaatgca cagcgaatga tgggaatggc ggctactatt
    12181 atagtgtttg tgctttaaag gtcaaagaca aactttgtat agtgactgac gcataaaaaa
    12241 atggcggttt tttggcggaa tgatggcggt ttttagccat ttatcagtga tattatggta
    12301 gtgtcgaaag attagtgata ggtctgagac aaaataataa taaaaggaac atcgttttat
    12361 tattgtttca caattaagct tcgatagaca gcaacggaaa tattaagaat aaggatgtga
    12421 attttaactc cttctaaatt gttcttatta tctatcatcc gttgctgttt attgttacat
    12481 acagatcgct taggcggtct ttttattttg gccgaaaacc tacattttcg atggccgatt
    12541 attggaggag gaatagcatg ttcaaactat ctgaaatcat taagaagtcc gacgttgaga
    12601 aattagagat gttaaaaaag aagttgaaga aatagcagtc tcttcgtgag gctgttttat
    12661 tttgctcaca aaaatagacc actatcgggt aatagtggtc aggaattaaa tgaaaaagat
    12721 gttagggttg ttagctaagt ataacatcat aacgcttaca aaacaatgca agaaggataa
    12781 attattatga gaacttactg gtatgtgtca ttaaacaata aatatccgaa gccaatgaaa
    12841 ggacagcata ggcgtgtagt catgtctgtt caaatgaagg cgaagtattc gattgtagaa
    12901 atgatcagag aggcaacgcc agtagagatt gattattgca agctagtcta ttgtgggtgc
    12961 ggccgttgga aagaggatca tgtacaaaaa aatatcagca agtacatata gagaggcggt
    13021 gattaaggat ggaaaaaagc gatacgaaag cgaacagata caaacctact gctgcagaga
    13081 aaaaactctt ggaagtattg ataaatccag ataacttagg caaaccggtg caagagttgt
    13141 gttcactggc gaaaataggt aggaccaaat attacgacgc catgagcaaa gatggctttg
    13201 ttgatctagt taacgaaaca acaatggatc tgatcaaagg aaaagcttct gatgtcctta
    13261 atgccactta caagtatgca ttgactgaaa aaggtcatca ggataggaaa atgattctga
    13321 ctattgctgg aatctatgca gacaaacaag aactcaaaca ttctggcggc gtcgatatcc
    13381 gaaaacagta tgagaaaatg tccgatgaag aattagaaga gttggtgaaa cggtatgaaa
    13441 aaatcaacga ctcttaatcg tgttgagtat gccgttgttc aaagagagct agccattcga
    13501 aaagctagga aaagtttttg gctattctgc cagcttcttt atccagagtt ttacaaagat
    13561 gatcggttgt atttgaaaga tttatgtcat acgctacaag atttttacga agataaaatc
    13621 gacaaaaaaa ttttggttat taacatgccg cctcgacatg ggaagacttt tacagcgcgg
    13681 ctattcgttt tatggatgtt tggacaaaat ccaaagacga aaattattac cggatcttat
    13741 aaccaaatcc tgtcatcttt atttgcgcaa caaacacgtg atggaatcat ggttgaaaac
    13801 gaaaatgtta aggctgaata ctttaaagat atttttccag aggtgcaaat caaatatgga
    13861 gatgctgcaa agggtttctg gtctttagat ggttcagaag aaaagaatta tttagcgact
    13921 tctcctggtg gaacatccac tggtattggc gcgaattatg taattgttga tgacatcatt
    13981 aaaaccgcag aagaagccta taacgagcgt gttttagatt ctcactggga atggtataac
    14041 aacacgttgg cccaacgaat ggaacggcca cgtaaacaga tattgattat gacacgttgg
    14101 tcaagtaatg atttagccgg aaaaatgttg acgagacgaa aaaataatgt tcatcagatc
    14161 tgttataaag cagtacaaga agacggctcg atgttgtgca acgagattat gacccacgat
    14221 gagtacttag atgtggtaca agaaatgaat gtagatattg cagaagccaa ctatcagcaa
    14281 gaaccaattg accaaaaagg caggctatat cagaagtttc ttacttatga tacgttgcct
    14341 gataacatta tcaaaatatg gaactacacc gacaccgccg acaagggtgc cgattacttt
    14401 gcgtctcctg tttttgctga gacgtctgat catgatgctt atattatcga tgtcatgtat
    14461 acaaaagagc cgatggaaac aactgaaata gcccacgcta atatgattat tcgcaatcga
    14521 gttaataagg tacggattga aggaaacaat ggcgggcgtg gattcagaag aaattcagaa
    14581 agaattacaa aagagcgagg ctatcgaggt gcagtatttg aagactttca tcaatcggat
    14641 aataaactgt ctagaatact ggcgaatagt gcttgggtgg aaaatcatgt ttactatcca
    14701 gatgattggg cgacacgttg gccggacttt tatgaggcta tggttagtta tcaacgtgaa
    14761 ggtaagaacg ctcatgatga tgctccggat gcagttacag gaattgcaga aacgattata
    14821 gaagcagatg acttcgagtt tattgcttat taggaggtgg gtctttgttt tattctggaa
    14881 tcacattgaa aaaatacaaa cgtttaagaa cgaaatattc aacgcaaatc gaagaaggat
    14941 tattcgatcc taacgctttt atggaagata tgaaaccctt tttcgatgat cgagaaagaa
    15001 agtatcttgc ttatactagc gagaaaaacg agatcgacag tcgtgagaaa ccaaaaacaa
    15061 aaatcattaa ggtcaataac aagattcatg cgggaatgta ttcagtggtc gttgatcaag
    15121 cagttaacca tttcacagga ataccaatta aatgggatta tgatgtttcg gaacagaaaa
    15181 ggacattcat tcaacgaatg agagacaaat tactgggtaa tgatatcagc gccccttcta
    15241 ccccagaaga atttgaaaca ctcacgagac aattaagtac tatgcggttt ggaatgttag
    15301 accccgatac tgcaacattt caaggagcga cagggcttgc tttcagatta ctggagcctg
    15361 ttgagacaaa tgatggttgg gaactaagag caagcaacat tgagccgtgg aaagctgaaa
    15421 agtacgaaaa cggcgcagtg tacattaaag agaaatacga tccatatcaa aagaagtttt
    15481 atgaagagat gaaggttgtc acgccgaaat caatatttac ttatgctcga tatactgatt
    15541 accctggcac ggtacaagga gcatttaaaa cgctgggtaa tgttcctaat cctttaggcg
    15601 ttatcaatct tacggagttt aaaaacaata caaaccgtta ctgtgacttt gaagttgcag
    15661 aggagattag tgatgctatt gatcgtgttt tatctgatca gcagaacgag attgaacaat
    15721 tcaagttagc ttatatgctg atcactgggg cagatttgtc cgaggataaa gccaagaaga
    15781 tgatggagca actagggatc atcaatctga aagaccctaa tgcgaaagcc ggctacgtga
    15841 caaaggatct acaaaaggat ttcaacgagt atcattttga tcttcttaaa aagcaattct
    15901 acacggtgtg taaagcaatt gatttcaatg acgaagtctt taagtcgaat agttctgggg
    15961 aagcccgaaa gtggcaaatc attagtttag aagctaagac aaataccaaa gaacagtact
    16021 ttcgagaagg attgaaagag tgtgccgagg ttatggctgc ttatttggat tttgccgaga
    16081 aagttacaat tgatccggaa aagatcattt tcaccttctc tcgttcgctt ccaacagatt
    16141 taagctacct agctgaggca ttgcctaagt tggcaccata cgtttctaag aggacgattc
    16201 aaagtcagat cccgttcgtc acagatgttg attatgaaaa cgaaatgatt gacgtcgaaa
    16261 gcagacaatc ttacccagac ggcgagtatg gaggtggcat cgttgagtca aatagaaacg
    16321 aagtactgga ccaaacgtcg agaactggaa gatttagcaa gactcaaaat ggaaaatcaa
    16381 acgctaaaga aactaagtag tgtctttcct gatgcgttga aagaaattca agcggagtta
    16441 ttatcccaag ctgatttaca cgatattacc tatgctgaga tgatggaatt ttatagtaca
    16501 agtgatcaga aaaaatatcg tgaatacgtt gaaaagaact acaaatcact gaagatgtat
    16561 gatgcaaaat acaaagagtt catcgaagaa tactttcctt ctttcgacta cgccaaagtg
    16621 aatcggctgc ttcaaatgag gtcagatatt tttcgaattc ttgcagagag tgcaatagat
    16681 gcagatgtga ataaatattt ttcggatcgg ttagaagata tcttgcaacg ttcgtatgta
    16741 tcaaacgcaa acgtatttgc ccagattttg aacgtagatt tgccgaatta cttatcaaag
    16801 gaagaacttg aacgttacct gaactatcct tggtcaggta agacattctc gcgtcgttta
    16861 tggggcaata tttcatctct agaacaaaag ctatctaacg ccattacaac tagtgtagca
    16921 agtggcgaag gagttctcgt ggcattacga acaatgcgag aagacccaga aatatgcgat
    16981 atgttcaaaa gggaggaatc gaagtacaac aaggcgatcg aaaatcttgt gagaacagaa
    17041 tacgctaaat tcgctcaaga tggtattgag aaatcttata ttgaaactgg cgtagacgaa
    17101 tacaatgtct taactgcaaa agatgaaaag gtatgttcaa tatgcggtgg caaagcaaag
    17161 aacaacccat acaagttgag tgaagcgatc attggtgaga accgtgcgcc ttttcatggc
    17221 cgatgcagat gtacagatgt tcctaatatg ccgaaattag gaaaagatat tgacgaagag
    17281 tatgagcgtt tatttggcga tttattagat gagtttgcac atgattcttt tggaattaat
    17341 ttgaaacgga ggaagtagaa tgaaagattt ttttgaagca gtactaacaa ttaatgtaaa
    17401 tgctgatatt gcagaagcct acaaaacagc tattgagtct gagaaccatc ctaatggctt
    17461 gagagaccat tggaatggca attatgccta cgtggttatt ggcgatcaaa ctgttaatta
    17521 tcaagataat actccagttg ataagaatac cgttaattta acgattcaat tattatctca
    17581 ttcattacca aatttaaaag aaacagttga ttggtatgaa aatatgggat gtattgttgt
    17641 tagaactgac tacaaagaag gaaagtctag taattaggct tttttatttt gtccgaaatg
    17701 acgttaaact agcgcaatac tgggcttggt tgaatggtgg ggcgcaacta ttaaaactca
    17761 aagcaatgcg gggcgtgaaa acgaatcgtg gggcgaaagg agaatgatta tgaaacacaa
    17821 atcattaatg ccaatgaatt tgcaatactt tgccgaaggt gacgatcaaa agttttcttt
    17881 tgatgacttc aaatcttttg tggaatccaa tgaagaagct caaaaattta ttcagtcaca
    17941 atctcaaagt gttgccgaca aacaattgga agcttggaaa caaaataact tagataaaat
    18001 taaacaggat accatcaagg aatatgagga atctaagaaa aacaagtcac ctgagcaaat
    18061 tcaactggaa aaactacaag ctgaatttga agcagaaaaa gcgttgcgtg tgacaagtga
    18121 taataaagca tttgttgcag aacaaattgc tggattagaa ctagatggag agttaaaaga
    18181 gtctatttct caatttatgc taaataatct tgttagttcg gatacagatt tcactaagaa
    18241 tgctgttgaa ggttttacaa gtgttttgaa tgcaatcaat gagaaacatg cagatgcatt
    18301 aaaagaacta caaatgaagt ctgcatttgg tggaactcaa caatcgaata accaagttca
    18361 gcagaacaat gaaacattta caaatccaga agaacaatta ggacaaattc ttcaacaatt
    18421 taactaggag agtgaaaaat tatgaaaaaa acatctttaa ataatttaga gtatttggat
    18481 atttcaccag cgattaatgc tatgcaagta ccaaatacac cttttttaag ctatttactt
    18541 ggtgctggaa agacagagca agcaaattca acagaaatta aatggcgtga atatgacatc
    18601 aacaacgatg attcttctga aaagcttgag ggcggagatt atccagatgc tgaatcgggt
    18661 cgaaattggt ttaacaacta tacagaaatt tttagaaaat caacctctgt atctggtaca
    18721 ttagatgcta ttaatgtgaa tggtgtcgga aacgagttaa ctaatcaagt agcactacgt
    18781 ggtatggaaa tgaaaattga cttgaacaga aaattgatta ctggtgtaaa agctgatgaa
    18841 aatggttcta aaggtcgtcg aatgaatgga attttgaact tgatcaattc agcaaataag
    18901 gcagaaacag ctactgcggg tgcagtaaca agaaaagata tcgatggttt atttaaattg
    18961 atgtatgaaa aaggttatat gggagaaaaa ttatgcttga tttctccaga tatgcaggag
    19021 ttaatgactg atgagttaga tggaaaatca acaaaaattg ttcagttcgg tgaaagagta
    19081 acttttggat tgcaaattgg aaatatcgtg tctaattacg gtacaggtat tgctttacta
    19141 gaaccatcat tgccaaaagg aacaattgcc gcaatcgata ctaattatgt gaaactacgt
    19201 ccattacgtg aatggagagc agaagaactt gcaaaaacaa ctgattcaag acgtatcggt
    19261 cttgtaggtg aatattctct tgaatacaac gcttcaaact ctggggcaat tttaaattta
    19321 aagtctgaat aaaagggagt tagtactccc ttttttgata ggaggaatta cagtggtaaa
    19381 aaaagatgaa actaaaaaag atgaagtcgt gaaatataga gtaggtaaaa ctaaaaattt
    19441 tgttggattt gttcatccta aaactcgtag atttatcaca gcagattcaa ataacgaatt
    19501 tatcatttct atagatgata aagaagcaat tgcaattttg gaagatgcaa ttgatgttaa
    19561 tgaaatttag gaagtgatct gatggatgaa tcgctaaaaa cggaaatcat tgagtctata
    19621 aaagaagatt ttccagattt gagtgaagaa cgcataacta atttattaga aataattttg
    19681 ctagaaattg aatcatacaa tagttgtaaa aatgatgttt catgggaaaa gttaaaaagc
    19741 gtgattagtg aagtgttgta tcaaataata aaaaatgaat cagaaaaaaa agtatcttca
    19801 gttagacgtg gcgatacgac gattagttat gcgtcaacag cgaatgctgt tagtgagtta
    19861 cttctaggat atggcgattt gatacgaagg gttattggtt gtggaggatt ggagtttttt
    19921 taatgaatga agcagatatt ttagaaacta cttacgaaga tagttgtatt atcgaaagac
    19981 taatggacat tgaagattct aatacaaata ttactattca agattataaa aaagtatatg
    20041 ataatcctat ttcttgcgct ctttcacaag gtcaaatcga tggactagca gtcatagaag
    20101 atggagagat ggtaaatgtt tcaactgaca catataaatt atttgttcat cctaagatta
    20161 aactaaaaaa aggagatcga ataacaataa ctcaaaaggc cagtggctta attttttctc
    20221 tatttgctac taagcctttt tactatccta gtcattgtga agtgaatttg ataggaagtg
    20281 agaaaaatgg gtaatctcaa atatgaatca aatgcagaaa agatcattga gaattttaaa
    20341 aatatgactg taattgctca aaaagaagga atatccttcg ttaacgattc aatgaataaa
    20401 gtcgttagtt tagctaaacc attaactcct gtaaaatcag gtaatttaag gcgaggatat
    20461 cgtgtagtaa aagctagaaa actatcaagc ggtcgaattg ttggagcagt tataaacaat
    20521 gaacattatt ttaaatatgt agaagaaggt cataggacta aaaatggtgg ctttgtcaaa
    20581 gggaaattca tgttaactcg tgcaacgaat cttgcaaata tgtcttatat tcctcgaaga
    20641 tttaaacaaa tggcaataaa aatcgttaag aaaggaaagt aacatgaaag atgaaatcat
    20701 tgctgcaatc agtagcaaat taaaagaaat ctatcctgat gggacaatat atcttgattc
    20761 agttatgcag tcaactaaag atttttattt cgttttatca gtaatggaat ctggaactga
    20821 aaatgtagga attgatattc aaaatgtttc tttcttaatt gatattgcat tgattgataa
    20881 taaacctaat agaaatttaa ttaatgaatt agtctcacgt tgtgggactt tttttaatac
    20941 gattacaatc gatgagcaaa tattatttcc aaaagcctat ttacctgatg aagcagatgg
    21001 tgttcaacat attcgtttta cattagaatt tccacaatat attgaatgga gtgaaagata
    21061 aatgggagaa aaaagaagta aaaccggaat tatttctgtc gaaaaaccta cttggtttcc
    21121 tttggaagat gagacaggga attttccggt atatggtact gcgttgccaa tgggaacagc
    21181 agtaagtatc aaaccaacag ctaattatga aacaacacaa gattatgggg attcagtggt
    21241 tcaagatcaa tttacagctt ttggtggtgc agaagttgaa ctggaagcaa atggatatac
    21301 tcataaagtt ttatctacaa ttactggagg gaaaattgtt aaaggtggtg ccttgcgttc
    21361 tggagaagat attgcgcaag atggtgcgtt tgcatataga cgtaaaaaat cgaatgggaa
    21421 ataccgttat acggtctttt ataaaggaca gtttgctcta gattcagatg aaacgtcaac
    21481 gattgaagga agtaaagtaa gttttactca tccaacttgg aagggttcat ttgtagatgt
    21541 accaggactt ggatatatgt attcagttga tgaagatgat gaaggcgtgg ataaagcaat
    21601 gatcggaaat tggtttacaa aagtagcaat tccaattgaa gaagcagaac tttcaggagg
    21661 tacagaataa tgtcaaaata tcaaacaacg attaaattaa cgaaaaaaga tgaagaaggt
    21721 aaatatgagc aagtacaatt taaatctgct gaatttttac caggaacagt tgtagaagat
    21781 gctgcaggag ttatggaaga aatgcaaaca gcgactgata aacaatcagt taaaaaagct
    21841 ttaagtcgtg cttattcatt tattgcagat actttatttg agggacaatt tactggtgaa
    21901 gattattgca aaggaattga tgctcgtgag attgcctcat tgacaggaaa attattgaag
    21961 tctgttactg caggttttga tgaaacttat acagagacga aaaaaaagta agtgaggcgc
    22021 tcaagtcacc ttcatttaag tattcgatta cttaccgaga attagatata aagacgcaat
    22081 tactcgaagc aggttggacg ttaccagaaa ttgaacgtac tgacttggat gagttaatgc
    22141 gtctttttgc ttttagagat gcggtaaaag agcatgaaga tgttgagtac tatgataatt
    22201 tcactcaatt ttaggaggtg atactttgaa taacgatgac ctaattctga agatgatact
    22261 agatgaatct ggttttactg ccggtatgaa taatgctgtc aaaaagttga actcttttga
    22321 tgaaacaatc gaaagaaaaa gtagaaatag tggcagttca ttaggtagta tttggaaaat
    22381 atttgctgga agttttctag ctagcggagt aactagaatc gtaggagctg gctttgatct
    22441 aatcaagggt tccataagtg gagcggttga tcgagtagat acgatgaata acgctctacg
    22501 aaatttccaa aatatgggat ttagtaattc agaaattatg aagaatatcg gaaagaatgg
    22561 gcttttatct caaggtattc aaggacttcc tactgctttg aatgatgcga taagtcatgt
    22621 tcaacttctt gcttcttcta caggtgattt aactcgttca actcaaatat ttaaagcttt
    22681 aaatgatgga attcttggtt tcggtggttc aactgatcaa gttaatgaag ctgttattca
    22741 attatctcaa agtttctcaa acggaaaagt agacgcacaa acttggaact caatgatcaa
    22801 cgctcaactt ggacctactc tttctgctat tgctaaaaag atgggaatta caatgggaga
    22861 tctgaaagaa ggtttatctc aaggtaagat ttctgttgaa gaattccaaa atcaattaat
    22921 agaaatggat accaaaggtg gcggaggact taaatcatta agtcaaatcg ctaaagattc
    22981 tactaaggga attaaaacct ctatacaaaa tgcaaaaaca gctgttacac gtggtgttgg
    23041 tgaggtaata gaaggattaa ataaagcatt agtagattca gatttaggtg gatttaaggg
    23101 gattattgat aaagttgcca gttccatgga atcttttttg aaagtaattg ctgcaaatat
    23161 tcctagagca gtgtcttttt taagtaatct ttttgatgca gttcaaaaat ttggctctgc
    23221 attgaaattc atgatgccat ttctggttcc tgcaactact gcttttggcg cattaatgtt
    23281 tcaacttaaa ggaataccaa caattataaa aagcttcaat aattttaaga atgccataat
    23341 cggtgttgga aattcactaa agattatggg ggctatagcc gccgcaaatc cgtttgtttt
    23401 gattgttgga gccgttgttg gagcgattgc tgtatttggc tattttatgg caaccaacga
    23461 agaggttaga aacaaagtta tatccgtttg gaatgatgta aaagattccg tacttggtgt
    23521 attaaagaat ataaaagatt ggggaattga tacttggaat tctgctaaag aaatggcatc
    23581 aaatgctgtt gagagtgtca aggatgcttg gtctggaata aaggaatggt tttcaaatac
    23641 ttggcaaggc attaaaaatg gagcaacagg tttatttgat aaaacagtag aaacatctat
    23701 gaatgcggtt gatagtgtaa aaaacgcatg gtcaaataca aagcaatggt tttctgatat
    23761 ttggcagagc ataaaagatt cagcaactga aaaatggaat gaaattaaag gttctatcat
    23821 ggaagttgct ggtccattga ttacaggttt aaagaacgca ttcttgcatg tcacttttta
    23881 tttagagacc ttatggaata atctagttga gattggtaaa aatgtttttg agattttaaa
    23941 aaatgttata cttacgccag ttttgtttat tacctccatg atttctggtg gatgggaaga
    24001 aacaaaaaat aatatgattg ctgtttggaa taatattaaa gaaagtgcca taaatatttg
    24061 ggaatctata aagaatatat ttgtaagtta ttttacaaat atttattttg ctgcactcaa
    24121 tatttggaca gggttcaagc ttacattgat aaatatttgg aatgaagtgg taaatcaagc
    24181 taaatcgatt tggttaaaca taaagtattt ttttattaat ctttggattg atataaaata
    24241 ttttgcaatt cagaaatgga ttgaattgaa gttttctatt attcaaactt ggatcgattt
    24301 aaaatataat gccattacta cttggaataa tattaaacag tttttcaaag atacttggaa
    24361 aaatattaaa gatacggcat acaatacgtg gatttctata aaaaatacca tgattaatac
    24421 atggaataac attaaggact ctttctggaa tattgttact ggaattgtta attctgctga
    24481 aaatgcatgg acaaatctaa aaaatggtgt ttcaaatgct attaatcggg taaaagaaat
    24541 ctttaattcg ttaagggaag tcaatttatt tgaaattggc aagaacatca ttgatggact
    24601 tataaatggt gtaaaagaaa agtggaatgc tttgaaagat actatcaaag gtattgcagg
    24661 taatatcaaa aattggatta aaggagcttt agatattcat tctccatcaa gatggatgcg
    24721 tgatatggtt ggtaaaaata ttgttcaagg tattatcgtt ggtattgata aagagcaaag
    24781 taagttagat caaaccatga caaatttagt aaaaacaccg tctgttcaac ctgtagtaaa
    24841 tggaataagt cacctaccaa ttacacaaac aaagcaaaat atatctgcta gtgaaacaaa
    24901 agaaattcat ttacatttaa atgtttatgg agatttacct gattcaatgg ttcggaagat
    24961 taccacaaaa attaaaacag aattgacaag acaaatgaaa cgagatgctg gtgcagtagg
    25021 aggaacatta tatgcaactt aagagaggac aattttttat taatcaacat tattcttctg
    25081 aatttaatgt gtatattcaa aacaggcctg cttctgtttc agctagtcga gtaattgaat
    25141 tgagagagcg agaaggaaat gattctatca ttattgataa aggctattac aaaaatgtga
    25201 ctagaaagat tgagtgttac tataaagcac cttcaattga tatggtgcag gagtgggaag
    25261 atcgaatcac tgaatggtta gatatgtcgt cttatagtga ttttattctt tactatgatg
    25321 aacaatatat ttatcaagct gtagtaatag aaggacctga atttaaagga acaagaaaaa
    25381 caggaaatat tgtccctttt gaatttacag tgagtattcg accatttaag gaaaattaca
    25441 atggtagatt tactattcga caaacagaaa cttttgaaat ttataaccca gagaagtatt
    25501 cttcaaaacc gcttattaaa ttgagtggtt ctggagatgc ttctttttat attaataagg
    25561 ataaatatga tttgaaatcg ttggacagag aattatttat agattctaaa ttagaagagg
    25621 cttatcgaaa attagatggt aatttagaac atcaggatca ggtcacctta tttttagatt
    25681 ttccattttt atatcctgga aaaaatgaaa ttaaatggac gaaaaatatt cattcatttg
    25741 aaataatgcc taggtggtgg agaaaagtat gaaaccaaga atatatagtc ctactgaaac
    25801 agatttctca acgaatggct taggaatttt aaaggattgt acaagatgtg gaatatatga
    25861 agtagctaat ggaaaatatg aattagagtt ggattatcct ttaggaacta gatttgatga
    25921 atattttgaa aatgactatc aaataaaagc aaagccaaac gatcaagaag agtatcatat
    25981 cttttttatt gatgataaag atatagatac ttttttaaat acagtaacta tttatgctca
    26041 gagtcgtaca aatcgacttg gaagacgggt agtcactctt gtggaagtgg actctaaaac
    26101 tggtcaagaa gcgatatcaa ttattgaaac taaaatggat aaaaaatctg acatacgact
    26161 ttattctgat attacggctg tttctagcac aatctttgaa gcgagaaatg ttttaaattg
    26221 tattgctggt gaacaaggat cattgcttca atattggggc ggagaaatta aacgtgaacc
    26281 atttaagctt tctttgttaa agcgaagagg tcgcaataat gttggaacga ttcggtatgg
    26341 aaaagatatg tctggtttga aggtcaaatt agattggaca ggtataaaaa caagaattat
    26401 tccatatgct gatcctcaaa gtgaagtagg tacgactaat cgaatttatg gttcgccagt
    26461 agatagtgcc tatattaata actatcctga tgtctataca gaacatgttc agtttacaga
    26521 agaacaagga gtaaaagaca ttaagagctt aaataaaata gctaaaaatt actttaaaac
    26581 gatcaatcct ggctgtgata agcctaaagt ttctattacg gttgaatttg ataagttgac
    26641 tgatagtgaa gaagcgaaag aatttgcgaa gattagaaat tatggtctgt ttgatacatt
    26701 taaaatatat cataaaaaat ataatattta tcttgaatca aaggttagtg gactacaata
    26761 cgattcttta tctgaaaaaa ctttgaaatt agaagcagga gacattcaag ttgcttttta
    26821 tcagcaacaa gctgtaacta ttcaggataa attaaaagat tatgcaacga ataattatat
    26881 gagtgatttt aatgattatg tttcttcaat gattacaggt caaggcagtg caggaggata
    26941 tgtagtttta tggccaaaag aaaaaccttc caacatcttt attatggata atccagattt
    27001 agaaaaggca agagaagtac taagaatgaa taaaaatggg attgcttttt ctaagaaagg
    27061 atggcggggg ccttttaatt cagcttggac attagatagt atatttaatg ccaattttat
    27121 acaaactgga ttaatcaaag cagatatctt tcaaaattct tttaacaaga ctggagatgt
    27181 attgaaatta gttaatggac tactccaaat ttggaacaac aaaaagaaaa taatggagtt
    27241 aactaaaaaa ggaatggaat tttggaattc taagggttca attggaacga ttggaacaac
    27301 tgattctgtt ggtaatcctt ttcctggggc ttctactcca acccctattg aagataattc
    27361 tttagttatt cgtacaaatg gagacggcaa atatattttg atttctccta aagtaggaaa
    27421 aggattagtt ttattaggaa atggtaaagc aatttatttt ggagacttag atgtacaagg
    27481 aaaacttaca gttaaaggaa aagaaataat tcctggacaa ggtggtggtc catcgggagg
    27541 tggagaatct actggtgggt atcctagtga attaaaaaca gatgcagaaa agagagcttg
    27601 gagaatttac gatattttgt gtaataacgg atttacgaaa caatctgcat gtggaatatt
    27661 ggggaacatt caacaagaaa caggaggaac ttttgatcct gatactgttc aaataggtgg
    27721 accagcatac ggattagttc agtgggatgg ttcttcatat cctcttgttg gtccagcaac
    27781 atgggatgga aaagtttatg ttcaaaactt atttaatgct gcaggtatta aagaaccaat
    27841 aacgagctta gatgcacaag ttcgattgct tatttggaca tttacaaatg gacaatggat
    27901 gggcgtagta caacctacga cggttgatgg atttaaggcc tgtactgatc caagacaagc
    27961 agcatatgct tttgaacgaa actatgaacg tccggcagcg acacatcctg aacgtcaaga
    28021 ttatgcagtt aactggtata acaaatttaa agatttaaaa ccaggaggag ctactggaga
    28081 agcaggacta aaacatttag agtctttgat tggacaacga attggcaatg gtcagtgtta
    28141 tggcttgtct gcagaatatt caggatatct gggtggttgt ggcatgggtg ctggaacaaa
    28201 atatggttta actcatgtga taggaaatac ttctgcagca tctgatattg gtattgccta
    28261 tgattggtct gctgttggtt ggaaagtgat tcaaaaccct agatatgatc aattagtagt
    28321 tggtgcaatt attaattggg caagaggtgg acaagtgggt tcatggtttg cagatggaac
    28381 ttatggacat actggcgtta tccgaggctt agctaatggt cgtatgcaaa cttatgaaca
    28441 aaacacagag ttaggtatga tttgtggaaa gttagatcgc cagtattata gtgcaagtgc
    28501 aatttcttcc attgtcatac caccaaaata gggaggtgat ttaatggcaa agtggaatgt
    28561 catattaagt acaacagaac cctataatta cgtggggatg attcaagttc gacaaggcaa
    28621 taagaataca gaggttatgg aagcgactat agttgaaaat ggtcttccct acgatttatc
    28681 agaatgtaag gtatattttg aatcagttgt aggtgggaaa tatccagtcc aattagaaac
    28741 aaaaattgtg gatgctaaaa aagggaaaat taactatatt tttgataaat attccatgca
    28801 gtgtttacat cgacaaacag ccaatttcat tatatttaaa ggagaagact tgattggaac
    28861 aactcaagac ttctcttatt ttgtcattaa tgctgtttca aaaacagaag gagaaatggg
    28921 ttcttattgg caatcaatcg aagatttaat tgcggatatg acggacttta ttaatgaaaa
    28981 taaaggcgat tttacggact ggatgaatga aaggaaagaa gaatttgaac gttggagaca
    29041 agaacaggaa cacagtttcc aagattggag agaaggacaa gaatcagact atttggcatg
    29101 gtttgaatca atcaaggata ttttaaagac gattgatcca ggtggagtca tgttagccga
    29161 actaacggat gcgcgagtag atattcaagg agttcgtcat gcgtctattt cagagcgttt
    29221 gctggcagat atggactatt tatatcagaa attgcgagca acgcttttca cgattgaata
    29281 cggggagatt gaagtgactg atattttgca ggatgatctc ttttcagata atcatgaagt
    29341 cgaaaaagtt ggaactgtag cattcccgat tgaagaagga gccttgatca tcgcaaccgt
    29401 tgatgatcca aagcaaaatg tgttcactct tgagaaagtt ggggtgatct aatggctaaa
    29461 actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac aacgccaatt ctttccaatc
    29521 acacatgctt ccgcagttct tgggttagaa gaaataatag caggagaagc aacagtttta
    29581 tctgttaatg gaaaaattgg agccgtcgtc attactaaag aagatttggg attagagaat
    29641 gttctcacag aattacccta tgcaagtgaa gaagatgacg gcattatcac ggcagaaatg
    29701 tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt tgccagttgc cactatcgac
    29761 cgtttgggtg gcataaaagt tggtgaatta ttgacgattg atgagacagg gaaagtctct
    29821 gcagtcagac aatctgatgt caatttttcg ctggagttaa aagaaaaact cgattcactg
    29881 aaaaattata ctgctggaga aaacatcact attgatgaag atggaacaat tagttctaca
    29941 ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag atcaaaaatt ccaagaagct
    30001 gtaaatcaag cagaaaatta cacaaacgaa agaattccaa attttacttt tgaaaaaatt
    30061 ggggaggtat agagaatgac agatatcgta aaaataaaac aaagcaatgt acaggtttat
    30121 ccacaaactc attggaatgc tatagaaggc aaaccaacaa cggtgaaggg agataaaggc
    30181 gatcctggcc aagcagcaac aattaccata ggaaccgttt ctagtggttc aaccgcttct
    30241 gttacgaatg taggaacatc atctgcagct agatttaatt ttgttttacc aaagggagat
    30301 aaaggtgatc ctggaataaa tgccacaact acagctgtag ctacaactac agcaaatggg
    30361 ttgatgtcgt ccacagataa aactaagttg gatggaattg cagctggagc acagaaaaat
    30421 ccaggtaatg ctacaactac gacagcaggt ttaatgtcag caactgacaa agctaaactc
    30481 gatggattag ccaatattac atttgagaaa gtggggacgg tttaatggct gatattgtgc
    30541 aattaaaaga agacggagtt gctaaatact taaaaacgca tgtagaagct attgatggta
    30601 aagaagcatt ggtgcagaca gatggagacc aagccattgc aggacataag aatttttcag
    30661 gttctgtaac aatcaataat aaacgtgttt tgacgactga tgataacaga tatgaagtgg
    30721 taaatctggt tgtcactaac ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa
    30781 cagtttctat atattttgtg gctttaaacg gaaaaagtag tggcgggaat gattcggtta
    30841 ttttaactgt tccagaaggc tatcggacac caattagttt tgaacaactg gttgggtcaa
    30901 tagaccgttc tactttgaac agtgctcaac tatctattgg cgcagacgga gccattaaat
    30961 ggagaagaaa ttcaagttat ggatcagctt attcatttgt tatcacttat tcaatttaag
    31021 ggaggaaatc taatgaaagt agtttacaaa tcaatcaagc cttacggatt cgagcaaatc
    31081 attttgaaca atcaagaaaa tatccctgaa aactgtacag agattaaacc accagttcct
    31141 aactggagac caagatttga ttttgataaa aaacagtggg ttgagttagc tactgaagaa
    31201 gagaaaaaag ggaatgctgt tgatagcgta gatgaattgg ctaatattaa ggcattatac
    31261 gaaacgctga aggcagaaaa tgatgaattg aaacagctaa attctaaagc aatgctaaac
    31321 aatgtagcaa tcaagcaaga aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag
    31381 ttgaattcaa aaacgatgct tgcttctgta caaaatacca aggaaatcga agaaatcaaa
    31441 aaacaattac aaggtgggaa gtaacatgta ttcatatgaa gatatcaaac taatgtatga
    31501 ctggggctgt ttcactaacg aacaagtaat ggttttcgtt ccgttgtgca ttactgaaga
    31561 agaagcagat aaaatcatta gcaaagaaga gagcgcatct taattgatgt gctttttatt
    31621 ttgattcaag gagttgtcac atgattaatt taggggaatg gggagcgata gcaggatcaa
    31681 taaccgctat cgtttctttg attttattag taataaaacc aattactgca tctttctcga
    31741 agattactga gactctttca aaagtaagtc acaatttaga tttgctgact aaagatttag
    31801 aatcgagcaa atcagatcga ttgatgattc atgaagaact aaagaaacac gatgaaagat
    31861 tagatacaca tacagaaaaa ttggtggaac acacgcaaca aattaaaact ttatttaggg
    31921 agagaagaaa atgaataata aaacgttcga agtactaaaa tggttcgcac tggtaattat
    31981 tcccgcacta gctactttcg tggggttagt tggtaaagcg ctcaattggc agtacacaga
    32041 tatctgtgtt gtcatcatta ctggttttgg cgcgttttta gggagtgtgt tgggtgtatc
    32101 aaatcgaacc tacaaaatgt tctcggctga aagcgaagaa ggaggaaaca aatgaaaaag
    32161 aaaattacta ttactgcgat gagcctgtta acggctcttt ttttattacc cattaatacg
    32221 tttgcttata ctattaatga cgagtataat ttagcgccga atcaaggaga ctccagatta
    32281 gcaattccta acaaaattat tttgcacgaa actggaatag atgcaccagc aagaaacgta
    32341 gccgccaaca tgaaaaataa ttataacgga agcaattctt atactacaga tgttattggt
    32401 gacggtggga ttgtttaccg tgtgggtgag caaggatatg tttcgtgggg agctggtaac
    32461 gctaatcctt atgcgcctgt acagattgaa ttacagcgca catatgataa agcattgttt
    32521 gaaaaaaact atcgagctta tattgaatat acaagagata gtgcaaaaaa atatggaatt
    32581 ccattgactc ttgatcaagg aacttcttta tttacaaaag gaatcatttc tcatttgtgg
    32641 gtgacaaatt atgtttgggg gaaccacaca gatccatatg gttacttatc gcaaatggga
    32701 gttagcaaag aaaagcttgc ttatgattta gctcatggat ttaccgatga aaatccaaca
    32761 acttctgaaa acaagcctgt cattgatcca acacgagctg gtgcagctaa tcctacgctg
    32821 acagatggaa caaatcacgc ccacattgat cagtttgggg aaatcgaaaa cgcaaacttg
    32881 catgtggctg gatggcacat tgctaactat aaatacgagt atattttcat tatggactac
    32941 aatactggga aagaattagc tcgagtaaga gctgatggaa tttatagacc agatgtaaac
    33001 caagcttata atacttctgg aaatgttggt tatcatgtat ctttcaatat gcgtaatttt
    33061 cctagtaaga aagtctatgt aatgatgcgg gcaacgaatg atccagaggg aaacactaaa
    33121 ggcggtgcgc aagatttcca tgacaaacgt tggtatttaa atattcctaa acgataaaaa
    33181 tagctcctcg ttgaggagca gtacataact atattgacaa ctataaaaat tattcgataa
    33241 aatagtgatg ttatcgcata tcttcactat cacccataaa tagtcacact ccaagctatg
    33301 cgataacagg tttgttgcca cacattctac tggttgattg tttatggctt tatgtggcaa
    33361 caaccagtac ccttagctca gttggtcaga gcagacggct cataaccgtc cggtcgtagg
    33421 ttcgagtcct acagggtaca ttaacgtagc catttgaatc gttctgtgtt agaatttttt
    33481 tgaagagtat tatacaagct aaagcttttc ttcattgcca ctcaaatgag tggctttttt
    33541 atgtatcctt ttatggatta atgaaaggat gtttcacata gttatacttc tgtatatttg
    33601 aaaagtttta ctttgatttt taaatagaaa gacatttggg ttaaattgtg agataataat
    33661 aaagaagagt ttaaagcgca ccccaaacca cttccccata agtgtgttac gctttaaact
    33721 cttttatatt tgaagccatt aaaaagcata ccatattttt gaaaaaaagt gagaaaaaag
    33781 gcttacaatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
    33841 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt
    33901 tcacaagtat ggtgataaaa ttcgttccgg gctacctttt taggtagcct actttaatct
    33961 ttataccttt ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgcta
    34021 cgtgcgtccg gcacgtcagt catgaatcgg ctacactaga ctagacagaa aaaataaggt
    34081 gtgtagaata ataaaaaaca cactggagga tttttcatg
//
LOCUS       DADQCX010000022        32968 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.022, whole genome shotgun sequence.
ACCESSION   DADQCX010000022 DADQCX010000000
VERSION     DADQCX010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.022"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(147..527)
                     /gene="yajC"
                     /locus_tag="J8R83_001000"
     CDS             complement(147..527)
                     /gene="yajC"
                     /locus_tag="J8R83_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAZ9574143.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(624..1769)
                     /gene="tgt"
                     /locus_tag="J8R83_001001"
     CDS             complement(624..1769)
                     /gene="tgt"
                     /locus_tag="J8R83_001001"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAZ9574144.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1987..2685
                     /locus_tag="J8R83_001002"
     CDS             1987..2685
                     /locus_tag="J8R83_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAZ9574145.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(2853..5492)
                     /locus_tag="J8R83_001003"
     CDS             complement(2853..5492)
                     /locus_tag="J8R83_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9574146.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(6111..7142)
                     /gene="queA"
                     /locus_tag="J8R83_001004"
     CDS             complement(6111..7142)
                     /gene="queA"
                     /locus_tag="J8R83_001004"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAZ9574147.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            7335..8510
                     /locus_tag="J8R83_001005"
     CDS             7335..8510
                     /locus_tag="J8R83_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9574148.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            8514..9155
                     /locus_tag="J8R83_001006"
     CDS             8514..9155
                     /locus_tag="J8R83_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574149.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            9152..10069
                     /locus_tag="J8R83_001007"
     CDS             9152..10069
                     /locus_tag="J8R83_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9574150.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            10066..10737
                     /locus_tag="J8R83_001008"
     CDS             10066..10737
                     /locus_tag="J8R83_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574151.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(11278..11766)
                     /locus_tag="J8R83_001009"
     CDS             complement(11278..11766)
                     /locus_tag="J8R83_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAZ9574152.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(11967..12233)
                     /locus_tag="J8R83_001010"
     CDS             complement(11967..12233)
                     /locus_tag="J8R83_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAZ9574153.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(12233..12496)
                     /locus_tag="J8R83_001011"
     CDS             complement(12233..12496)
                     /locus_tag="J8R83_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9574154.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(12489..12761)
                     /locus_tag="J8R83_001012"
     CDS             complement(12489..12761)
                     /locus_tag="J8R83_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574155.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            12972..13157
                     /locus_tag="J8R83_001013"
     CDS             12972..13157
                     /locus_tag="J8R83_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9574156.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(13299..15122)
                     /locus_tag="J8R83_001014"
     CDS             complement(13299..15122)
                     /locus_tag="J8R83_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAZ9574157.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(15720..18425)
                     /locus_tag="J8R83_001015"
     CDS             complement(15720..18425)
                     /locus_tag="J8R83_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAZ9574158.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(18731..19678)
                     /locus_tag="J8R83_001016"
     CDS             complement(18731..19678)
                     /locus_tag="J8R83_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAZ9574159.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            19868..20137
                     /gene="rpsN"
                     /locus_tag="J8R83_001017"
     CDS             19868..20137
                     /gene="rpsN"
                     /locus_tag="J8R83_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAZ9574160.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(20313..20675)
                     /locus_tag="J8R83_001018"
     CDS             complement(20313..20675)
                     /locus_tag="J8R83_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9574161.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(20686..21807)
                     /locus_tag="J8R83_001019"
     CDS             complement(20686..21807)
                     /locus_tag="J8R83_001019"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAZ9574162.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(21823..22173)
                     /locus_tag="J8R83_001020"
     CDS             complement(21823..22173)
                     /locus_tag="J8R83_001020"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAZ9574163.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(22303..23814)
                     /locus_tag="J8R83_001021"
     CDS             complement(22303..23814)
                     /locus_tag="J8R83_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAZ9574164.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(24136..25488)
                     /locus_tag="J8R83_001022"
     CDS             complement(24136..25488)
                     /locus_tag="J8R83_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAZ9574165.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(25641..26717)
                     /locus_tag="J8R83_001023"
     CDS             complement(25641..26717)
                     /locus_tag="J8R83_001023"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAZ9574166.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            26913..28658
                     /locus_tag="J8R83_001024"
     CDS             26913..28658
                     /locus_tag="J8R83_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAZ9574167.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(28938..29375)
                     /locus_tag="J8R83_001025"
     CDS             complement(28938..29375)
                     /locus_tag="J8R83_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAZ9574168.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(29359..30732)
                     /locus_tag="J8R83_001026"
     CDS             complement(29359..30732)
                     /locus_tag="J8R83_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574169.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(31054..31542)
                     /locus_tag="J8R83_001027"
     CDS             complement(31054..31542)
                     /locus_tag="J8R83_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574170.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(31564..32166)
                     /locus_tag="J8R83_001028"
     CDS             complement(31564..32166)
                     /locus_tag="J8R83_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAZ9574171.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
     gene            complement(32235..>32968)
                     /locus_tag="J8R83_001029"
     CDS             complement(32235..>32968)
                     /locus_tag="J8R83_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAZ9574172.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT         9420 a         7011 c         6041 g        10496 t
ORIGIN      
        1 taaagttatt tattattatt tatatgacac acccgattat tcaatattga gcaatatatc
       61 ccatgctctt atctctttct tttttgaata aaaaatgagg taggacatct ttctgcccta
      121 cctcgtcttt aaataagctt tgatacttat ttttcttcct tctcttctgt ctcttccagc
      181 gtttctgttg tttcagtttt tacttcaact gtctcagctg gttcttctgt tgtttcaaca
      241 gtagtcgttg catcatttgt tacgacagtc cctggtttga ccgttttgat tgctgcacga
      301 tcgtactcaa ggaagatccc ttcgcagtct aaaacaactg tccgtttgtc attgtcgatt
      361 tctgaaacaa ctccatgtaa tccgccgatc gttacgactg aatcacctgg tttcatgcta
      421 tctaacaagt tttgacgttc ttgctgttgt ttcttttgcg aacgtgacat aaaaaaccac
      481 attgctaata gcgcgataaa catcacaagc attggtaatg ttcccatttt tttcacctca
      541 ctaattctgt atctacaaaa aacactttag cagaaaaatg ctgataacac tagtttttta
      601 cttaattttt aaaagatttt cctttagaag ctttttgcgt tttctttatt gaacccgtat
      661 tcttcaaaaa aggcttctct aaattcaagc aaattatcat ccatgattgc ttgacgtact
      721 tgtttcatta gattcaacaa gaagtataaa ttgtggtaag aagtcaaacg aatcccaaat
      781 gtttcatcac atttgatcaa atggcggata taggcacgtg tatagttttt acatgtataa
      841 caatcacatt tctcatcaat tggacggaaa tcatgggcat atttcgcatt tttcactact
      901 agacggcctt gagaagtcat acatgtgcca tttcgagcga ttcgagtagg caagacacag
      961 tcaaacatgt ctactccacg gataacacca tcgatcaatg aatcagcagc accgacaccc
     1021 atcaagtaac gtggtttgtt ttcggggatc aacggtgtag tgaattctaa tacacgattc
     1081 atttctgatt taggttcccc gacagataac ccgccgattg agtaaccagg gaaatccatc
     1141 ccgactagat ctttcgcgct ttgacgacga agatcttcaa accctgctcc ttggatgatt
     1201 ccaaataatc cttgacggtc tggattagca tgagctttca atcctcgttc tgcccatcga
     1261 gacgtacgtt ctactgattt tttcacgtag tcgtaacttt catcgaatgg tggacattcg
     1321 tcaaaactca tcatgatatc agagcccaat ttattttgga tgttgattgc tttttctggt
     1381 gataaaaaca tacgcgaacc gttcaagtga tttttgaaat gcacgccttc ttcttcgata
     1441 ttccgcatat cacttaatga aaaaacttga aagccgcctg aatctgttaa aatcggttga
     1501 tcccagttca taaatttatg cagtccgcca gcttcttcta ctaagtcttc accagggcgt
     1561 agccataaat gatatgtatt acttaaaata acgccagcac ccatttcttt caactcttct
     1621 ggggacattg tttttactgt agctaatgtt cctactggca tgaacattgg tgtggggaaa
     1681 gttccgtgtg gcgtgatcaa ttcccctaaa cgcgcgccag tatgtttttc tttcttgatt
     1741 aaacgatagc gaatggcagg ttgcgtcatt catttcccta ctttctatat aaaatatctt
     1801 gacaactccc accatcataa tcgtttcaag tgctttttgc aagttccctc ggcttccttc
     1861 tactttattt aatattcttt tttttatcct ttttttatga ataacaaaaa aaagaaaaac
     1921 attatgacag aaatattttt tgatacatgg tatattggtg ttattaaaga aaaggaggga
     1981 aaaatcatgc aatcttctgc agaattaaaa cgccaagcaa aagagagtct aaaaggacgt
     2041 tggggacaag ctgttttact aaatctaatc cctacattga ttggtattgc tactattctt
     2101 cttattatga ttcctattat cttgtttgcc accaccatat atgatggatc agcgagcgtc
     2161 tcagaagcga caacttcagg aggcggtagt tcaggaggcg gtggcggaat tatttccagc
     2221 atcattagcg ctttgttcat gagcggtatt tcttggactt atcttgatat tttacgtgga
     2281 caaaaagatc agatcgaacc attcaaagat gcatttcgtg gattcaaagg tttgtttatc
     2341 ggcggagtga tcagcttagc tgtgctgatc tcgatcttta caacattatg gggtttgcta
     2401 ttagttattc ctggaatcat taaaagctat tcttattctc aaagctattt tatttactac
     2461 gatatcgtcc aagaaacagg acaaacacct aaagtactgg atacgatcac tgcaagtcga
     2521 aaattgatgg atggttataa aggacaactt ttctggttag atctttcatt tatcggctgg
     2581 catatcttag cattagcaac tgctggtatt ggttatctat ggctcagccc atacatttct
     2641 gcaacaaaag cagcatttta tgaacaattg ccaaaagata tttaaaagag agtgtgactt
     2701 gtgaccgagg gggtggcagg agaacaccgt ttatcgagag gcagtaaaag aaacattcag
     2761 cccattagca aaaaggaggt gtgacaacat tcatgtcaca cctccttttt gtatagttcc
     2821 agtaaaaaga aaatcaactt agaaacagtt aatcattcct cttcttctgc ttccggtaat
     2881 cgatggaact tgatcagttc attcaccgcg attggtacga tagataaaat ccctaccaag
     2941 aaccagtgat tcaaactgat gtgtactagg ccgaatagtt cttgcgtaaa tggcagcaaa
     3001 gcaacagccg ttgtaatagc taatgccagt aacgccattt ctaccaaagc tttattggtc
     3061 gctaaattga ctttgaagat cgattggctg ctgcgtacat tgaacacatg cagaatcgat
     3121 gaataagcta agatcaagaa tgcaacagtt tgaccgacat gctgacttgc gtctacccat
     3181 gggctgatag tatcgacata actacctaaa taataaccaa acaaggttac gatggtgaag
     3241 acccctgcat ttatggcaat tttttgcaat aaacctcgag caaagatccc ttcatttttc
     3301 ggaatgggtg gctgatccat gatgccgtgt tccgctggct ctcttcctaa agcaaatcct
     3361 ggaagtccat cagcaactac attgacaaac agtagttgca cagctgtaaa tggtgctccc
     3421 catcctaaca gcatcgcaat caaaacaata aagatctccg aaatattaca gcttagcaaa
     3481 aagttgatag ctttacgaat attctgataa accgaacgtc cttgactgac agcgtctacg
     3541 atcgtcgcaa agttgtcatc cgtcaaaatc atatctgcgg cactttgcgc cacatctgtt
     3601 cctgtgatcc ccatggcaca cccaacgtta cttgctttca acgctggtgc atcattcaca
     3661 ccatccccag tcatcgctac gactgcaccc gtacgttgcc aagatttgac gatccggatc
     3721 ttgtcttctg gcgttacccg agcatagaca gagagagctt tgacacgcgc atctaattct
     3781 tcgtctgata attgatgcag ttctgatcct gaaagtgctt ctgacggatc attcaagata
     3841 cctaattctt tcgctatggc actggcagtc accacatgat ctccagtgat catgactgtt
     3901 ttgatgccag cctttttcgc tcgcttgatt gctcctttac tttctggacg tggtggatcg
     3961 atcattccga tcagaccaat caaacgtaag tctttttcca gtgcttcaga agaaatatct
     4021 tgcggttctt cgtcataagt agcataacca acagcaatca ctctcagtgc ccgtttacca
     4081 aagcgatcat taacgatcgc cgcttgttct acatcgcctg aactaaagcg cggagcaaga
     4141 acatcgaatg ctcctttggt gattgagatg tatttttcgc ccatttggtg aactgttgtc
     4201 atcatttttc gttcagaatc aaaaggaagc tcgtttactc gtggatattt ttcttctaat
     4261 tctgcctttg tatgataatt ctcttcaaca gcccttacga tggctacttc tgttggatta
     4321 cctttgataa caaggtcgtc atcttcttgc tcgaccgtca catctgtaca tagtgcagcc
     4381 attttcaata tttccatcgc gctgttcgtc attgaatctt cgatattcgt tacttcatct
     4441 tctttgctcc atacccggcg gacgcgcatt tcattttgtg tcagcgttcc tgttttgtct
     4501 gagcagataa cattagcggt tcctagcgtt tcaactgctg gcaactgtcg gatgatcgca
     4561 tgtttcctcg ccatcttctg cacaccgtat gcaagtgtca acgtaacaat aacagtcaag
     4621 gtttccggta cagctgcaac agccaaggaa atcgaagtca tgaacatctc aaggagtggt
     4681 tctccttgca gttcaccaat cacaaatact aaagccgcag ccgctaaagc gatcatactg
     4741 attcgtttgc ctagctgatt caatcggacc tgtaaaggtg ttttttgcat agtattttcg
     4801 ttcaaaagat ccgcgatctt acccatttct gtagccatgc caatggcagt gacgatcgct
     4861 ttcccacgac ctgcagcaac cgtacatcct ttaaatacca tattaagttg gtcacctaat
     4921 gactcatctt cttcagcaat aaatgctgca tctttttcaa ctgcttcact ttctccagtc
     4981 aacgccgatt cttctacacg taattgtgat gcttcgatca aacgggcatc ggcagaaata
     5041 gcatcaccgg actctaaaac aagaatatca cccactacca gttgctctga ctcaacagtg
     5101 gtcactttgc cgtctcgtat gacagttgcc gtttgtttat tcatatcttg caaggattcc
     5161 agtgcttttt ctgcgtttcc ttcttggaca atcgccaata ccgagttgat cacaacgata
     5221 gcgatgatca gcagtccttc aaataaatcc ccatgttctg tagcaaatgc ggtataaaag
     5281 gaaatcaccg ctgctacaag aaggatgatc gttgtaaaat cggacaagct tcgaaagaat
     5341 tttttgatca tcgattcttt cggcgcctca tcgaatttat tcaatccctg cttttttcgc
     5401 cgttcatcca cttcttgtga agacaaccca gtatctggat ctgcttctgt taccttcttt
     5461 acttcttcta ttgtctgctt gtattcttcc atcctattcc tcctttaaaa tcttcgtaca
     5521 aaaaaaggta cttattttac tataacatcc tttttttatt tacttcaaat aaagggctta
     5581 tcgattattt gttaagaaag cgtaaaattt aaagtgctta tatttgcaaa cgctaccaaa
     5641 ggatgctatt atatagatgt aaggaaggag gataccatca aatagacaga agaatttctc
     5701 gatagaacag tgtaagcaaa caaagttgtt agaagtacag gtttcaccca gacatgcgtg
     5761 tagagtacaa acctataaat agtgaatgcg tatggatgtt tggatcacga agtatccgaa
     5821 acaagaagta atgcgatacg taacaattga ataacgtaaa cgtctgaaaa ttgaatagga
     5881 acaagagatg tttcaaatgt tgaagatgta acgaaaacaa aatttttgtt taacatgaag
     5941 aaattcaaca ccgtgctttg catgtatgat ggaaagttac aatcatttct gtttatttga
     6001 atccttccga ggtacaagaa agccgagctt atcgagagct cggctttttc tttgtcataa
     6061 aatctttgta aagctttttt gttattcaaa actagcggct tttcataacc ttatttcacg
     6121 aacatcgcat ctccaaaact aaagaaacga tagcgctctt caatcgcatg ctggtaagca
     6181 gataaagtca attctcttcc tgcaaaggca ctaactaaca tgactaaagt cgattttggc
     6241 aaatggaaat tagttgagaa agcttctacc actttgaatt catagccagg cgtaatgaaa
     6301 atatcagtcc atccgctgtc tgctttgatt tctccattaa atttcgttcc aatcgtttct
     6361 aatgttcgaa ttgaagttgt tccgacagcc acgattttcc cgccattttt acgtacttgg
     6421 ttcaatcgct cagccgcttc ttccgtcaaa cggtagaatt cactatgcat atggtgttct
     6481 tcaattttat ctacgctgac aggtcggaat gtacctaacc ctacatgtag tgtcagatag
     6541 actaattcaa caccctttgc ttcgatctca tcaagtaatt ctttcgtaaa atgcaatcca
     6601 gctgttggcg ctgcagcaga accattttct ttcgcataga cagtttgata gcgatctggg
     6661 tcttccagac gttctttgat atatggaggc aatggcattt ctcccaatga ttcaagaatc
     6721 tctagaaaaa ttccttcata ctcaaagtca atgatccgtc cgccgtgttc caattcttct
     6781 ttcactactg cttgcaatct gccatcacca aaagagattc ttgtcccaac tttggcacgt
     6841 ttcgcaggtt tgatcaatgt ctcccacgta tctccttgtg tattcgttag aagaaggact
     6901 tctaaatgcg caccagtatc tggtttttct ccatataaac gagcaggcag aactcgtgta
     6961 ttattcataa ctagcgcatc accaggctgt aactcttcaa tgatttcatg gaaatgttta
     7021 tcttccatct ctccagtttt ccgatccaaa acaagtaaac gagaatgatc gcggtctttt
     7081 aatggtgttt gtgcgattaa ttcttccggc aagtcaaaat caaaatcttc tgttgttaac
     7141 atatcgtcac tcactttcta tcatgtgctt catcattcta tcatgttttt cgttctgttg
     7201 gcaaaatcag cactttttca cttctatttt ttgttttcct aaataaaaaa actaccctat
     7261 ttgtattttt tcattgtttt aggcatacta gtaatagata gttcttcatt gaaaatagaa
     7321 aaagaggtgg caccatgatt gaatttcaaa atgtgtcaaa aatttataaa ggtggaaaag
     7381 tcgctgtaga ggacgtcaat ctttcatttg aaaagggtga gttcatttgt tttatcggta
     7441 cgagcggaag cggaaaaacg acgacgatgc ggatgatcaa ccgaatgact gatccaacac
     7501 aagggaaaat tttgattgat ggaaaatcca tccaagaaat tgatccagtg gaattgcgac
     7561 gtcagatcgg ctatgttatc caaagtattg gattgatgcc tcacatgacg atccgtgaaa
     7621 atatcactct tgtccaaaaa ttgttgaaag tcagtcaaga agaacggaat aaaacagctg
     7681 aaaaaatgat tgatcttgtg gaattgcccc gtgagatgtt agatcgctac ccacatgaat
     7741 tatctggtgg tcagcagcag cgtattggag tcgttcgtgc ccttgcagcg aatcaagata
     7801 tcatcttgat ggacgagcca ttcggtgcgc ttgatccaat cactcgtgat tccttgcaag
     7861 accttgtcaa agatttacaa gagcgtttgg gaaaaacgat cgtatttgta acccatgaca
     7921 tggatgaagc gattaaacta gcaagccgta tcgccatcat gagtgaaggc cgtgtgatcc
     7981 aatttgatac accagaaaat attttacgtc atcctgcaaa cgatttcgta gaagagttga
     8041 ttggagaaga tcgcctacta caagccaagc caaatgcgac aagagtcggc gaagttatgc
     8101 taaatacagc aatcacgatt acaccggaaa aatcattaca agaagcaatc aaactgatga
     8161 gggaaaaacg tgtagatacg ttgttagtta ccgataattc gaatgtatta aaaggattta
     8221 tcgatgtaga aacgttgaat aaaaaacgag gaaaagtatc cagtgtcggc gacattttga
     8281 ataaacatgt tttttacgta aaagaatccg cctatcttcg tgataccttg caacgcattt
     8341 taaaacgcgg gctgaaatac gtgccggtcg ttgatgaaca gaacaaagtc gtaggtatcc
     8401 tgactcgtgc atcattagtg gatatcgtct acgatgtgat ttggggagaa gatcccgcaa
     8461 ctactgatgt tgcagagtca gctactcctg aagaatctaa ggaggtctga cctatgcagc
     8521 agttttttca tcagcacggt tcagaaattc tctcaaaagg ttttgaacat ctttatattt
     8581 caggacttgc tttgatcatt ggtatcatca ttgctgtacc gcttggtgtc ttactgacac
     8641 gttttccaaa agctgccacg attgtgattg gcttaaccag tgccttgcag acaatccctt
     8701 ctcttgcttt attggcattg atgatcccgc tatttggcgt aggtaaatta cctgcgatta
     8761 tcgcactctt tatttattca ttattgccga ttttacgtaa tacgtacatt gggatgaaaa
     8821 atgtcgattg gaattatcgg gatgtggcaa aaggcatggg gatgactgag ttccaatcca
     8881 ttttttccgt tgaattgccc attgctatgc caacgatcat ggctggtatt cgtttagctg
     8941 ccgtttacgt gattgcatgg gctacacttg cctcttatat cggcgctggt ggtttaggcg
     9001 atttgatttt tagtggactg aataattacc aaccagatct cattttggca ggtacgatcc
     9061 ctgtaacaat tttagcacta ttggctgatt ggcttctagg tctcttggaa caccggctga
     9121 caccgatcgc acttagagag gagaatgaag aatgaaacgt atactaaaaa tgaccatggt
     9181 tcttttctct cttcttatac ttgcgagttg ttccttccct ggtcttgcca gcaatacaga
     9241 tgaagacacc atttcgatca caggtggaat cacttcagaa gcacagatct tagcaagtct
     9301 agttgccgga atggttgaac attatacaga taaaaatacc gcaatcatca acaatctggc
     9361 tactacaact atcaaccatc aagcgatgat gaacggagat gcttcaattt cagcggctcg
     9421 ctacacagga acagatttaa cgactacatt gaaccttcct cctgaaaaag atccgaaaaa
     9481 agcgtttgct accgtgaaag atgaatttga gaaaagatac ggtcaaacgt ggttcccgtc
     9541 ctatagtttt gaaaatacgt atgtctttct tgttcgaaaa gacaccgcac aaaaatacca
     9601 tctatctaaa gtcagcgatc tgaaaaatgt agcggatgaa ttagtagctg gtgtagatac
     9661 ttcttggatc aatcgtaaag gagacggtta tgacggcttc caagaaactt atggcttctc
     9721 cttcaattcg atattaccta tgcagattgg acttgtttat gacgcagtcg aagcaggaaa
     9781 aatggatatt gttcttggct actctacgga tggacggatc gccagttatg atctagtcat
     9841 gttggaagat gatcgtcaat tcttcccacc atatgatgct gctccagttg tagacaacaa
     9901 gatattagct gatacgcctc atttaaaaga agccttaaat aagttaggtc ataccatcag
     9961 tacggaaaaa atgcaggaat tgaactacga agcagataat aatctagtgg aaccatcagt
    10021 agtagcacaa cgtttcttac aagaaaacca ctattttgaa gggaagtgaa gcaattggat
    10081 aaaatgaatg tctttcaaca atttttctat tatttccagg aaaatggctc ctatatcttt
    10141 gcacaattta tccgtcactt cctgatttct atctatggtg tcctctttgc agcagttgtc
    10201 gggattccgg ttgggatcat gatttctagg agacgtaaat tagcaaactg ggtgattcgt
    10261 ttggcgaata tcatccagac gatcccttct ctagccatga tctccatttt aatcattgga
    10321 ttaggcctgg gagtcaatgt cgtgattgtt actgtatttt tgtattccct cttaccgatc
    10381 atcaagaata cgtataccgg gatgatccaa gtagacaaaa acatccttga tgtcggcaaa
    10441 ggcatgggga tgactgctag acaacgacta ttcatggtag agttaccact ctctgtttct
    10501 gttatcatgg caggcataag aaacgcgtta gttgttgcca tcgggataac cgcgatcggt
    10561 gcattcgtcg gtgctggtgg tcttggagat atcattatcc gaggaaccaa tgcaacagag
    10621 ggcacatcga ttattttagc aggtgcattg ccaactgcat taatggcgat catcacggac
    10681 tggcttttag gtattttgga aagacggcta gatccagcca gccgtacatc acgctgatgt
    10741 tattgtaaaa aacaaaagct tctgcgacca tttgttggtc gcaaaggctt ttttagttct
    10801 gtcattttta aggcaataat ccactctgat tcttccctcc ttatgggcaa agagttgctt
    10861 ttcttagcta tttatccatt ccgtatactc caacttcata ctgccaacgg gttcatatct
    10921 gcatccaccg actaagtttt tttcttatcc gctaaggcat tttgccaatc cattttccca
    10981 tcactcgtca tggaattcat accacatgat ctctaaatac tcgtctgctt gttctttgaa
    11041 ttgggcatca attcttacat cctttggcgt ggctttcatt taagcctttt ccatcagtcc
    11101 tcgattgttc gatgccttca gctgcatcat caaaactggt gactgccgta tcggtaactt
    11161 cgatcatctt ttatacaatc gggaacttgc catcctcatc cttggctaaa aacatatcta
    11221 gccattccag cttctcgcca tgggaggttt gcggttccta aaaccggtac acgattctta
    11281 tggactgcat ccgtcgcaac tagacttggc gatacgatga tccttcacca gaagagcacc
    11341 cccgtaaacc aattgatcga tatattgcca ataagaaaag acattggcgt aaaagatatc
    11401 gatccctcgt gatgcattgc cgttgatact gctattcatg gccgaaagcg ccacgacttt
    11461 aacttcttcc gtttgagtga cattcatgtt cggcaatgtc gctttggata cccgctctgc
    11521 taaaggaacg acactggtat tgtatttcgt atctgtatct tttccaaaag accatgccaa
    11581 cgaatcctct gggaaccaat aagacgactc cggttgattg tccattgctt ttttcaacat
    11641 acttttggct gtttctcgat aaacgacatt tccaattgtc ttcgcctcac tttggcgata
    11701 atcgatggtc gttgccactg ccaacactaa caacgatgct ccaattttac tgattttcct
    11761 tgtcacactt cttcctcctt gttttacata aacccgtcaa cattccattc ctaaactcaa
    11821 acaatgaccc ttcaaaggtg gagatatagg aacaaattaa agaaatcatg caataaatcc
    11881 aagaaggttg gttttagaac aaaaaaagag tctccttttt ggggagactc tttgttaact
    11941 atctaaaaag gttggctctt ctcacttcac tcataatgtg tccaggcaga ataaatttct
    12001 acaactttat tttcctcatc aactttgtaa accactcgat gctgtctatt cagcctgcgt
    12061 gagtatctgc cttcatgtgt aggtctcagc ttttcaaaag actgcgtggg catatatgga
    12121 tcttccttca atgtctgaat cacttcttca aattgtttct ttaaattcgt ttgcttgatt
    12181 tttcttaaat ccactttcgc agagtttttg attgcgactg tatagttact catcaaagag
    12241 cttcccaatc aatatcatcg atattcgtaa agctactgtc gtctttttcg cggtctcgta
    12301 ctttatctaa agtacctgtt tgctcaagaa aaagggtttc ttgaatcgct ctccagtctt
    12361 ccagcccaat caatacagca ttgtttccac tacgatcact aataatctcg atttcagtat
    12421 gattttcatt tacctctttc aataactgat aaaaattttt acgagcagtg ctaggattca
    12481 tcgttgtatt agccattgtc tctcctcctt tttctgatat aattatagcg tacttgatta
    12541 agtacgtcaa aaaaatacaa taaagcactt aaattcagca aacttttcct cttttttaca
    12601 tagagaaaaa gacccctttt tagggaggat ctttgtccac gctcacttct tactccttta
    12661 cgactagcgg tagccaaacg taaagtaatt ggtaacaacg tatcatcttt agcaaaggtc
    12721 gaatccaaag cctgtgagtc tatgcaacaa caccaataca cgaaggttcc tcgttgcagt
    12781 gtgacttgat tgatatcttg aataacctga ggatacgcac gaaagatttg taacggttat
    12841 tcaaaactga ttttggccgt caagtcttct actgcctcaa aaatgattgc ctctttcgtc
    12901 tcctgtcatt catgttcact atcgatttga tacttgctta gaccgttggg tttgtgaatc
    12961 accaattaaa aatggcactg agttatggta acaaaaaatg gtcacttgac gaggctgaga
    13021 ttcctactta tgaagacaca tggcacttaa gagtcgaggt aaaggaagaa gctgaaaata
    13081 taggaggctg tacattattt ggcaaaggat tcggaaatta tgatcaagac atcaaaatca
    13141 aaatgtttta cagctaaata ggaagaataa taacatttca tacgctgttc ccatctttaa
    13201 tggcttatag agggcacctt tagctgagaa taagacaaaa cagaccctct agcttcaatt
    13261 aagagctaga gggtctgttt ttgattttaa aacttggttt atttcttcaa atggtagcta
    13321 taggtgctga caacgatatt ttcacgccaa gacaatcgca atcttaaccg caaacttgtt
    13381 tggttatgga gaatattctg ccagcgtctg tttggtacaa attgaggaat caacacagta
    13441 gttgtatagt tttgtttcgc tgcattttta cttacgatat ctacataacg gataattgga
    13501 ttttcaatcg agcgataaga agagtggacg attgaaaaac ggacatctgg gaaatgcttt
    13561 ttaaattctg cttcgatttc tttttctttt tcgacatctt cgtctagcga aacatgcatc
    13621 gcaacgacat aatcaccgat cgaacgtgcg taattcaacg caccgatatt tacccgtgtc
    13681 acattcccga ctaatacaag aacggtattc ccgtcataat catgtagttt tgcatcattt
    13741 tctaaacgaa gctgttctgc tactttttta taatgatcat ggatcttata aaaaatgaac
    13801 ataacgattg gcataatgat gaagaaaggc caaatgtccc ctaaccgata gacaaacaaa
    13861 atcgcaatga ttgcatatga gatgaacgca cccgtaatat tggcaatcga tttgcttaac
    13921 catctttttc cttctttttt ccatttgacg accatccctg tttgagataa agcaaatgga
    13981 atgaacacgc cgatagagta taacggaatc aagcgttctg ttgagccatg gaaaataaac
    14041 agcaatacga tcgaacctag cgctagtgtg ataatcccat tggaatagcc tagtcgatcc
    14101 ccacgatctt gatacatgtg aggcatgaat ttatcttttg ccagattgta tgcaagaact
    14161 ggaaaagcag aaaaaccggt gttagcagca actgctaaaa tcagcgctgt agcaaattga
    14221 aggacgtaat acaaaatacc atgtccaaag acagctttac caatttgaga caaaacagtg
    14281 acttcttttt caggaacgat cccataccaa tagttgataa atgtgatccc cacgaagaag
    14341 aaacctaaga tcaatgccat catcgtcaat gtagcagcgg cattttttgc tcttggcttc
    14401 ttaaagaatg gtacagcatt actaatcgcc tccaccccag ttaaagagga agaaccagaa
    14461 gaaaatgctc gtaaaatcaa agcgatagaa acacccggca cagccgctcc tggaagtgca
    14521 gtagcttgca atggcacagc acctgtcacg atattatata aaccaacaac gatcagtaac
    14581 gagatcacaa ggataaatgt gtacaccgga aataatagga acgatgcaga ttccctcagc
    14641 ccacgaagat tcagcatcat cagtagcaaa acgattgtca cagaaatagc gacttgatga
    14701 ccgtagagtg ctggcaccgc tgatgtgatc gcttcagcac ctgctgagac agatactgct
    14761 actgtcaaca tgtagtcgat caataaagag ccaccggaaa tcaagccagc attctttcca
    14821 agattctcac tgctgacgac atatgctccc ccgccatgag gataagcatg gatgatttga
    14881 cgatatgata gcgttaatga aatcaataaa ataataacaa aagcggcaat gggtagcgaa
    14941 taccagatgg ctgcagcaga caaagcgact aaaacgacaa cgatttgttc cgtaccatat
    15001 gcaatagatg ataacgcatc agacgacaat aatgccaaag cagcaaatcg ggttaatttg
    15061 tgctcatcat tttcagcaga ttttaaaggc ttacctacta acaacctttt taagtaatcc
    15121 aatttctaaa ctcctttaca cacaatttta cttcaagttt tatagtcgaa aatttatagt
    15181 aaacaagatg ttatagtacg ctcactgacc ttaaaagtca ataaacttta agaaaataat
    15241 tggaaaaaaa cagaaaaata tcaagcgctt tttcaaacgc tttaatacag caaaaatcta
    15301 acattttttt atgggctttt tctttgaatt ctataataaa aggatagaac ttgacttaga
    15361 aaatcaagtt ctatcctttt tgatatctta acttttggaa gagagatgta aggctgcttt
    15421 ctacccatca ttcttactac tcgaagcata gcgcagttgt cacaacctct tgataaacgg
    15481 tgtttaaaag cttgcatctg cggtaataag cccaaccaaa ttaaaaacat aagaagctgt
    15541 ttttatttgg tcgttcttat tacttgatgc agagcagctt ttttacaacc tcttggtaca
    15601 cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa acggcaaaat atgaggaact
    15661 atttttccat ttttttctct aatactcagg tcaaaacact gatttcacaa cctctttttt
    15721 taatgaaaaa tatggctctc atgcgccgct tctttgaatt tcgtcatttt ttcttcgatg
    15781 aacggataga ttgccgttcc tacgattcca aagacaacaa acaaaccgat catgatccag
    15841 attgctttcg tagcatttgg ccaataaatt cctcctgcag attcccgtaa caagtttacc
    15901 gcatgagtaa atggcaagaa cggattgatc atttggaaga atttccctga gacttggatc
    15961 ggatagttcc cgcctccgcc agagatcgac agtactaaga tgataatagc gatcccttta
    16021 ccgacattat cgaataatgc agccaagaca tagacgatca tcatgaacgc taaggcgatc
    16081 aagacagcaa atgacacgct gtagaccgga ttttggacat ctactcctag taagaaaata
    16141 ttccctaatg taacgatcaa gctttgcgca atcgccattg tcaaaaatgt cagcatacga
    16201 gcaacgaatt gttctcgttt cgtaaaattg tttcggtctt tctttcctaa atagtattct
    16261 gtcgtagcaa cacttgaaag aagaacagcg ccgacccaca gacatagtgc agtataaaac
    16321 ggggtgctag ctgaaccgtt atttgcgatt ggataaagcg cattggtttg tagctcaaca
    16381 ggttgtgtaa agaagtcact ttcttttgtt gcgtctagtt tcaataattt gatgacttcg
    16441 cctagatcga cttcttgttc gccttttcgg atcgcgtctg ctgctttttg gataccagct
    16501 ttgatatttg gccagtcatt gttgatcaag tccgcagcag cgttcacagc tgtttcgact
    16561 tctggcattt tttcatttac tgttgtcaat gtaccggtga tttcattttt tagtgctggc
    16621 caatcatttt ggataaaatc agcggccaat cctaattttt gctgaatgat cggtaattca
    16681 ttgttgtata ggtctgcccc ttcattgatg ccattgacga tggtatccat atttccattc
    16741 agcattgtat tggcatcatg gatttcttgt ccaattgcag gcatttcttt ttgatatttt
    16801 tctaaaattg ccactgcatt cgttacagtt gctttcgttg agctgagaag cgaatcaaag
    16861 tcgatctggt ccgctttgct cagtgcgcct tgtgcagtcc caatcgtatc gatgacttgg
    16921 tctagtagag aagtgacagt ggaactgatt tgacctgtat tgataccagc aatgatgcca
    16981 ttgatattat taacaacggc atcaatttga tctagcaatt catcaatagc cttcgtgtct
    17041 tcattttgaa cagctgtgtt caaagcagat aggcggtttt gcagattgct tagcaagggt
    17101 tttaattgat ttagctgatc aataattggc tgtaatttcg tatttccagc acttgtttgc
    17161 aatttagtca ggaactcgac cagtttatcg attgcatttt gttgttgaga tattccgtca
    17221 ataaagccgt tcaatacatt gctgatgttt ttcttttcat catcagtcag cttaccatct
    17281 tcaatagctg ttcttacagt atctattaac gaacctgtcg ttgttgccac ttgtccaatt
    17341 gacttcaatg taacatctac actgtttgtg atgcttggta tcgcatcttt cagctgagag
    17401 gcacctgatt ttgtttggtt tgctagatca cttgcctgat tttctaaatt tttcacatct
    17461 ggcaagatat cttgtacttg ttggatgatc gtcaagcctt gttttgcttc atcgattcct
    17521 tggttcattg tctcttggat cgaagcaaaa tcgccgtcga tctctgctag ttgcttaccg
    17581 gcattttgga tctctgggat tttttcttgc aaatcaagga tgatttttgc ttgatctttc
    17641 aactcaggca ttttgtcatt caatgcaacg actttttcac ccatctcatc tactttaggg
    17701 atgtaatcca cgaattcatt tgctttattc agtttttcct tgatttcagg tagttgactt
    17761 tgtaattcga ggacttgttt tgtgtagccg tcgatcgtgt ccaaattttc atctgttgat
    17821 aaaatcatat ctttaacttt attgatactt actaggttcg tatcgatgtc gtaacctatc
    17881 tcattgaata ctttcaataa agtcgaactg gctgttttga taaattcatt tgtgatttgc
    17941 gattggatcg aacttgctcc tttatcggtg attttcggtg caatcgcatt gattttttca
    18001 tttaccgtat attcgatttt tggtttcttg atatcaccac tagtaaaact cagcagatct
    18061 tctgagaaat cctttggcaa gtaaatacct gcgtaatact ttccggaacg gactccgtct
    18121 tctaattgtt cttttgaatc aacgaattgc catcctaatt gtttattttt atgaagcgat
    18181 tcgatgactt gctccccaat ggccacttct ttaccttgaa actctgctgg cttgtctgca
    18241 ctgtaaacag caattggcag ctctccagta tttccatatg gatcccataa tgctttgatg
    18301 ttaaaccacg catatagcga agggatgatc atgatcgcga tgatcagaag tgttgcaatc
    18361 gggtttttga aaatccgttt ccagtcaagc aaatataatc gaagcgtatt tttgattgac
    18421 tgcatagttc tcccccttct tcttttttca gctgaattac tttaccatgt atttcatact
    18481 tttttcaatc ggcttttttc aaaaaagtcg aatttttgga catatcacgg caattgtctc
    18541 attgtaatct cttacatatt gagaaataat taaggattac agcctttact ttatcatgaa
    18601 ataaaaggga aagataattt tatgccaaag tttttatcta ttatacgtat acgcaaaaaa
    18661 gctaaaacat tttttgtctt tgcccctaca aaaatgtttc agcttttttc gttttttatt
    18721 cctgtatttc ttatttttcg aatgacagga tgattttccc agcaggagga tgtccttcaa
    18781 ctagctgatg tgcttggatg acatgcttaa gtgaagcaga cagattcatt gaaataaaaa
    18841 catgaaaggc tcctttttgg taggctttga ttatgccagc aaaggcttct gcatctagat
    18901 attcctttct tggaacaaac gattcataaa agccttcctt tttttgccgc aaatctagat
    18961 ctgggaggtc atttaatgca acatacctgc cgcctggttt catgatctgg atgccggttt
    19021 ctcctttgat acttcctttc gtcgcatcga ttacaaggtc tgcctgatca gcaaattgca
    19081 gacctggatt tgttttatca taagcagcaa atgctgaagc tcctaatttt tttacctttt
    19141 cctcattttt actggatgca ctggttaaga ttcggattcc cttttcatgg agaagctgga
    19201 tcagacttga cccgaccgca cctgatgctc ctagtatcat tacagtatct gtcggctgga
    19261 tttccgtcaa atggttgatt agattataag ccgtaattcc tggcgtgacc attccggctg
    19321 cttcttccca actcatttta tctggaattt ttgctacttt tgctgatggc aacacgactt
    19381 cttctccgta agtcccgccg actgcatgga cagctactcg atcacctaca tgaacagttg
    19441 tgacatctga accaatctct gtcacaatac cagcgccatc attacctggt acataaggga
    19501 atttcaatgt tcgtatctct ttcatttctc ctaaacgcaa ggcaacatca taaggattca
    19561 cactgaatgc ttttatttct acacgaacat gtccagaacc gacttctctg ggatgagcat
    19621 cgatttcttc aaaaacatct tgtgcttctc cgtaaccgtt aattgcaaat cttcgcatgg
    19681 tcaccatctc cctttttctt taagtttacg tttatgcctt tattttgaca aaaaaaatgt
    19741 cttttcgttt tggcgcatga ttcaaaacaa aatagttgtc ttttttcgcg taacgtgtta
    19801 aattatttat ctaaaagcgt aaagattacg atttacgcta ataaaaaata attggaggaa
    19861 tttgttgatg gctaaaaaat caaagattgc caaagcaaaa aaacagcaag aaacgattga
    19921 acgctatgct gctttacgcc aggaattaaa agcgcaaaaa gattacgaag gcttgcgtaa
    19981 acttccttta gatgctcgtc cagaacgatt gaaaaatcgt gatttaatcg atggacgccc
    20041 tcgcggatac atgcgtaaat tcgggatgtc ccgtataaaa ttccgtgaat tagcacataa
    20101 aggtttgatt ccaggagtaa aaaaagccag ctggtaatcc aagtctggct gtaatgtaaa
    20161 ggaggagggc gcatggacca ctccttggat catcaaaaaa gatacgttcg cttcttctag
    20221 cagaaatgct ggtactagaa gcagacgtat ctttttttac gcacagctgg tcctttttta
    20281 tatgtaaagg ctgcatggtt acttcgctat atttatttag taacaggagt cagtgcttcg
    20341 atacccacac taattttcaa tgctcggtca acttctgcca taatgggtcg atccaaatgg
    20401 cagacctttt ctttcaatct tgatttatcg atcgttctga tctgctccaa caggataacg
    20461 gagtctcttt ctattcctgt tccagtagct ttgatcccaa tgtgagtcgg aagcttaggt
    20521 ttagccattt ttgccgttat ggccgcaaca atgatcgtcg ggctaaaatg gttacctaga
    20581 ttattttgaa taaccaaaac tgggcgtgtt ccgccttgct ccgatcccac gactggagaa
    20641 agatcagcaa aataaatatc tcctcttttt accataggat cctccttatt cttgatattc
    20701 tcttggtatc cgctgtccta atccgcaagc cacttcatag tggatcgtac ctaattgatc
    20761 tgctatatcc tgcatagtga tttctttgtc tgcatttttg ccgataagcg tcacttttgt
    20821 tccgacagga aattcttgag gcaatcggat catcagttga tccatacata cacgcccaat
    20881 cgtttcacag tagttccctt ctaccaatag agaaaaaccc tgcatctttc gtggccagcc
    20941 atctgcataa ccgatcggta tcgttccgat ccactctgct tcaggagtga tatatgtttc
    21001 tccatagccg attccttcac ctgctgggag ttttttgact tgaatcaatt cagaaaccag
    21061 ctcaagtgct ggctgcaatg gataaacttc cggtagtgcg tgcccagagg gattaagtcc
    21121 gtacattgct actccataac gaatcatatt gccgattgtt tcatcatgcc ataaagccgt
    21181 tgcactattg ctgacatgta catatcgagg aagttcggga agttttttca gcacttctat
    21241 aaagcgttct ttttgcagat tccaatatgt atcatctgcc tgatctgctg tagaaaaatg
    21301 ggtaaataaa ccttcccatt ctaatacacg actttctttg atgaatgcag ctgcctcttt
    21361 tacttcttca ggtgtacaaa atccgatacg acccatccca gtgtctgctt ttagatgaat
    21421 cgaaagaggc gtctctagct tacttttctc taaaacagca gctgctgctt gcaaccattc
    21481 ccgtgtacct gcagttactg ataaatcatg agcaacagct acagtcagtg cgtcgtaagg
    21541 aaccatattc aagataagga tgggctgagt aaatccagct tctctcaact cgactccttc
    21601 atctaaattt gaaacacaaa agcccgaagc tccacctgca actgctgcct cagctgtttc
    21661 aatagctcca tgaccgtatc cgttcgcttt tactactgca aacaattctt ttccttgcgg
    21721 aagtcttgca acttcatttg ctacattttc agttatagct tttttatgta tcactgcttt
    21781 cgttgggcgg tgccaagcga caaccatcgt ttttccttct ttctagtctt ccaaaataat
    21841 ttgtgcaaaa gctgtttcat ttgtatgagt aatactgacc catacattgc cttcatgagg
    21901 tgaacgcgtc acaacaggct gaccattttc attttttaaa atctcgacat cttgaaaggt
    21961 aacttttccg atcccagttc cccaagcttt agagaaagcc tctttgcaag cgtaacgccc
    22021 gcctaaaaat tctacttggc gatgaaaagg caaggactgg aatagtttca tttcatcaga
    22081 ggtcaagatt cgtgcaatga attttggttt ttcttcgatc agccgagtga tcctaggaag
    22141 ttcgactgca tcgatcccaa ttccttttat catatgcttt tctcttttca ataaatttag
    22201 aacactctca ttctaccaaa ttataaccat tttgccacaa ataagtccac aaataacaaa
    22261 aatgaaagtt tctcttaaaa aagagaaact ttcattttat gtttaatcgt tatttgaacg
    22321 gattacaaat ccgcgttttt tatcattgtg acgtttaccg ccatcttttt ggctgttatt
    22381 atttttgcta taaccgcctt ttgatttgtt tccacgataa ttaccgccgt cacgacgatt
    22441 acggttgttt ccgccaccac gtttgccatt tttattgtat ccttttttct gcattggcaa
    22501 tgggcgttct ggtgtgatct tcactggcac tgcatcagct ggatcttttg ctgtcgtttt
    22561 tagcaaaagt gcaactaaat cttgtgcaga atattcttct aataatttat ctgctgtttg
    22621 caggtattta tctagaccat tttctgcaag ttttgtttcg atttgttcaa ctgcagcacc
    22681 taattgacct ttgaatgctt ctttttcggt tggtggacgt aaagtcgtca tccgtttttt
    22741 cgtcaagttt tcaatcacat gcaagtagtc catttcattt ggtgtaacga aagtcacaga
    22801 cataccgcct tttccggcac ggcctgtacg tccgatacgg tgaacgtagc tttctggatc
    22861 ttgagggata tcatagttgt acacatgagt gacacctgaa atatctaatc cacgtgcagc
    22921 aacgtctgtc gctacaagga tatctaaatg accgctctta aatgaacgca atacgctcat
    22981 tcgtttttgt tgagacaaat cgccatggat tccttctgca cggtaaccgc gtgcttctaa
    23041 tccgcgtgcc aattcgtcta cacggcgttt tgtacgtccg aagacgattg ttaattcagg
    23101 tgtttgaaca tcaaacaagc gagtcatgat atcgaatttt tcgtattctt ttgcgcggac
    23161 atagtattga tcgatcaagt cagctgtcat ttctttcgct ttgatcttca catgatgtgg
    23221 atttttcatg aatttaacgc caatattctt gatagctggc ggcatcgttg ctgagaaaag
    23281 taatgtttgt ctttgatcag gaacttgtga aatgattttt tcgatatctt ccaagaagcc
    23341 catattcaac atttcatctg cttcatccaa aactaatgtt tgaacggttc caagtttcaa
    23401 tgtgtggcgg ttaatgtggt caagcatacg tcctggtgta cccacaacga tatgtggacg
    23461 atctttcaag ccacggatct gacggccaat atctgctccg ccgtaaacgg cttgtacacg
    23521 tacttttttg tcgcgcccta aacgatataa ttcttcttgt gtttggatag ctaattcacg
    23581 tgttggtgcg ataactaaac cttgtaattc gtgacgatct ggatcgattt tttctaacat
    23641 tggtaatcca aatgcagctg ttttccctgt acctgtctgt gcttgtccaa taacgtcttt
    23701 tccagctaat gctagtggaa tcgtttctgc ttggataggc gttgcttctt caaaaccagc
    23761 gcgttcgact gatttcaaca attctggtga taattctagt tctttaaatt tcaaatgaat
    23821 cctcctatat ggttgttaac tgaggatgta gcttttttgc taccccgtcg atttgttcgg
    23881 tcaaagtgta ttgtttcttt ttgacagtgg ccacgcacgt ttttatccat tcttagcccc
    23941 tgtggcacca ccgaaaaatc actttgcgaa gtttaggcat tagaaaagcc aaacgggtcg
    24001 cgttcagctt tatcattatt atgacatctg gcttcaacaa gttgtttcta tggcaaaacc
    24061 agtccaattt ctcttcatct ttcggcaata ggttattcta acatagtttt tcgttttctg
    24121 caagtttaca gatttttatt tcatttgctg aagttgttct accacttcaa ataagcccat
    24181 gctgttgctg ccttttagca taatactatc tgttgcttca agattttgtt tgatagcatc
    24241 aatcaattta ttcttttctt tttcaaaata gaacacaggt agttgggggt atttttggtt
    24301 caattcttct tttagtgcat gcatttgttc cccataaagg aaaatcatgg cgaatttctc
    24361 aggatcgata tgttcactca tttgcgcatg catatttaaa gactctttcc ctaattccag
    24421 catatctgct aacacagcga ttctgcgtcc ttttgttggc agatttttaa aagtatctaa
    24481 taccagtccc atggctgttg gatttgcatt gtagacatcg ctcaaaatag ctgcaccatt
    24541 tcctgccgtt agccattcgg ttctgttttg agtgatagaa acatgggcga gcccttggcg
    24601 tatctcaggt atggacagtc caaagaagcg cccgatcgta tacgcaatca aagcattcgt
    24661 tacattataa cttccaggca gcgggatcgt aaatgtttct ccttctacta caaaatcggt
    24721 ttgtgctttt ccttttgctg tcacttccgc atgaacatcg ccatttccaa taccgaatgt
    24781 tgtgactgtt tgtactaatg ttgccgttaa aggtgtcagc aacggttcat ctgcgggcac
    24841 aacgagtaat ccgtctgata caagtccgtc agtgatttcc attttggctt tagcgattcc
    24901 ttctcgcgac ccaagatttt ctatgtgtgc ttcaccgatc attgtgattg ctgcagcttt
    24961 tggttgagcc ataagtgaaa gttccgtgat ttcattggcg tgatccatgc ccatttccaa
    25021 aacgatcttt tctgtatctt ggggcatgtg caaaatcgtg taaggaagac caatattatt
    25081 gttgtaattt ccttgcgtct tatatgtttt gtatttttca gacaagacag acgcggttag
    25141 atctttcgtg gtggttttac cattgcttcc tgtaattgca acgacttctg cgcctacttt
    25201 ttccaagtaa taggttgcca attgctgcat ggctttcaaa ggatctgcta caggaataac
    25261 tggaaaattt tttggagctt gttcaacagg caagctccaa aatgaagcag atgctccgtt
    25321 tgtgatcgct tgctggataa attcatgtcc atctcgcgta ccagcaagag gaacgaataa
    25381 acttccttcg gttatcttcc ggctgtcaaa ttcgacattg gtaatctttg tcagtgcaga
    25441 gcattcgctg cccacggctt gtgcaatttc ttgtattgtt agattcattg agatctctcc
    25501 taaaaaaggt tgtgaaaaaa gcgtttggcc taaacggcgg gttcgcatga ctctcacttc
    25561 caagtaaatt tctctattcg tatttagaag ctagaatgaa cgcggttacg caatcactcc
    25621 agcctcttct ttatttctct ttattcattt ttttcaaaaa aagattgacg ctgatggtat
    25681 cgattcattc ctaactggat cagttcttca atcaaatcac cgtatttcaa gcccatattt
    25741 tcccataaga gtgggtacat actgaactcc gtaaatcctg gcatagagtt taattcattc
    25801 aggaataatt catttttatt tgtcaaaaag aaatcgcacc ggctcaatcc gcttccacct
    25861 aacatcgtgt aagctaactt cgcgtactct tgcgcttttt gataaacttc ttctggcact
    25921 tcggctggaa tctgcatttc gattttatta ttgatatatt ttgcttcata atcatagaat
    25981 gctacgtctt ttacgacttc accaggcaaa gtcgtccgaa cgtcttcatt tcctaataca
    26041 gcaacttcga tttcgcgcgc ttcaattcct tgttcaacga ttgctcgaga atcatactga
    26101 taggctgttg ctaaagcatt ttgcagctct tctcggtttt ctgcttttgt aatgccgaca
    26161 ctagaaccca tattcgccgg tttgacaaac atcggataaa gcaaagaacc ttcacattga
    26221 tcaaatactt ttttaggatt ttctttccat tgattcttaa gtactggtac ataaggaact
    26281 tgcggcacac cagcagcttg taaaatatac ttggtcatga ttttatccat ggcacatgca
    26341 ctggtcaata cgcctgcgcc gacataaggc atattcaatg tctctaagaa gccttggatc
    26401 gttccatctt ccccgtttgg cccatgtaaa actggaaaaa cgatggctcc ttcttctttg
    26461 atttcgcccg gattgatcac ttttcctgta aagccttcct ctgtctgtcc acttgggtcc
    26521 catgaaagat gcaagacatc tttgctggca ggtttttctg ttagtaatgg acctttgacc
    26581 cattgtcctt cttttgtaat aaatacgagt tgaacttggt aataattata ataaatggca
    26641 tttaaaactg aaaatgcgga aagaatggac acttcatgct ctgcgctgcg tccgccatat
    26701 agtaaagtaa tcttcaaaag attgtcctcc tgtattctaa atcgttcagt gatttactct
    26761 catattttag cacaaaacaa aaataaacga ataacttatt tataaaaaaa cgagccagct
    26821 tctaaaagaa cgagcgtcat ttattttttg tcagctagat tatttgtccc gttttttata
    26881 aaaagttatg ataaagaaaa ggagggatga tgatggcgca aacaaatcca cgcagccgct
    26941 tggcagaaat cattcgagtg ttcatcaatt acaatgtagt gccaaacttt gtacagcaaa
    27001 aaaatcccga acaggtaaaa aaagcctttg aagaactagg ccccaccttc atcaagatag
    27061 gacagatgct ttctgttcga gaagatttgc tttcttctgc cttcactcaa acattcaaaa
    27121 cattacaaga tagtgtacct agcgacacat tttcaacggt caaaaagacg atcgaaacag
    27181 aactttctct ttcattatca gatatattcg atgatttttc aaaatcgcct tttgcctctg
    27241 cttctatggg gcaggctcat cgtgccaagc tgaagaacgg tgacgcggta gtcgttaaga
    27301 tccaacaccc taacatcgcc gaagagatcc gacttgatct tcaactattt gaacgagcga
    27361 tccctttgat caaatacatt cctgaaacta gcgtagttga tctaaaaggg gtactccaag
    27421 aagtaaaacg ttccttgatc aatgaaatgg acttcttaaa agaaagtcaa aatggcgaac
    27481 aattctatca aaagaacaat ggctggaaag agatccgcag ccccaagatt tatgacgctt
    27541 tttgttcgaa aaaagtgatc gtgatggaag aaatgtctgg taaaaacttg aatcatttaa
    27601 tgaacgccga aaacaaaact gaaactttta tcactggaat tcaaaacaag cagctgaaac
    27661 aagaagttgc aaagctttta gttgagaact ttatgaaaca ggtgtttgat gatggttttt
    27721 tccatgctga tcctcatcca gggaatctgc tattccatgt actaacaaaa gaagaacaga
    27781 cacaagctag ccgaaaaact gaaacagtcc atgaaaaaga gttcggttcc tttgcttttc
    27841 gagcctccac ttctgcagaa gaccctgttg cgccatatac catcaactac atcgattttg
    27901 gtatgatggg gcatctttct gcaggactta ggcaaaaact cacacaagcc gttttagcgc
    27961 tgtatacgaa agatgcttat cgaatcgaaa aagcggtcct tcgactttgt cagcaagaag
    28021 gctcgtttga tgaaagtcgg ttccaccaag aactgacaag ttttcttgaa cagtattatg
    28081 attctcctat tgatgaaatc aacttgcaag aagtattcac acatgtcgtg acgatttgtc
    28141 atcaaaataa tctgcagttc gatcgtgata tcacgctttt gctgaaagca tttgggacat
    28201 tagaaggggt gatccgcgtc ctcgatcctg aagtttccct catggaagtc gcttcgcctt
    28261 ttgctcaaca ttattttctc actcatctgg atgtagaaga tacattgaaa caaagcggat
    28321 tagacttatt ggaagggatg aaggctgcgc ctaagatccc tcaacagctc caccatctat
    28381 tagaaatgtg gacttcggga caaggaaaag tcaatttgga attgaaaaag caagacaaat
    28441 tattgagcag gatcgaaagt atgatcaatc ggcttgtttt cggtatgatt ttagctgcat
    28501 tgatcgtagg gtcctccctg cttgtccaag cagcacctgt agaaaacgca gaggtcgttt
    28561 ccttattagg gatatttacg tatgctattg ccgcattcgt cattattttt ttggcaatcg
    28621 atgcattgat ccaaatgtat aagaagagga aaaagtagaa aaaggttgtg acagaaagaa
    28681 tcagcttcaa gaaataagaa ggggttttac ataaattgtt tctcaaattt ttgtgaaaat
    28741 tcggcttatt tttcgaagag gctacttctg aaacaccgag aataaaaaat gtgaaaaagc
    28801 tgttctgcac ccagtaataa gaacaatcaa aaagggaaca tggaacacat ttatcctgtt
    28861 tccctgttcc ctttttgatg tattcgagca taaataaaat accttcgtta cctactatct
    28921 tctgtacttg gtaaacctta gtcaattgcc ttttttaacg cttgacgaaa agacatatga
    28981 tctttctccg taaagggttt tggacccttt gtccttatgc cagcttttct taactttcca
    29041 ctatgataac gttgttctag aagcgtgccg atattcgctt cgtcaaattc ttttccagag
    29101 tgatggaaca ctcgcacacc cttcggcaat acaagtgaag ctaaaccata atcttgcgtg
    29161 atcaaaaagt cattcttctt aaccataccg acgattttat aatccgcact atcagctccg
    29221 cggtctacgt agacgatttg gacatgatta gcgtattctt tggtcgtata atggtccaca
    29281 ctggtcacga taaccacgtc aagaccatag gattctccta attttatgac atcttctttt
    29341 actggagaac catctccatc aatgaatagc ctcattcttt ttcgccttct tccataaatg
    29401 ataaacagtt actaatccgc tcagtaaaag accaacattg atccattttg ccaagataag
    29461 cagttgtaca ctttctatcg gcactgattc atggttcagc gtgatcaata atagatggat
    29521 tggctctccc atttcttttg ctaaaacaaa caaaagcgtc atcaataaaa actggtggat
    29581 cacactccct ttattttgag tagtatactt gacaacgatc cggcgatcca ttggaatagc
    29641 tgtatcagtt tgataatatt ccttatttag ccagctgcct gttactacgt gccagaaact
    29701 aagcagaaag acacctatcg caaaaccatt tggaatcaag aggaccaata aagaagaact
    29761 cagtccaagc aattgcatag ccaatggaga ccatgttaaa cgtttcaaaa tccatggtcc
    29821 gactattttt gctgcaatca agcctgctgc ataaggcaaa tacataaaaa tcgaaagttt
    29881 ttctaatccg tacagtatgc caacataaaa actgctaaat aaaaaaagga aattccctag
    29941 cattccattt agaaaagtaa acagatttag ccagcttggc aacttccatt ccttcttctg
    30001 gtgtcctaaa acaaacacga acaagatgaa cagcagcaag aaaccataaa tagcaagatc
    30061 aaaaagcctt tcatcgaata acaatcgggc atttctcaaa agaaacaata agccaaagaa
    30121 tatcaaaaat aaaacaagct ctcgcgtagc taccagattt cttttgatgt ctttgaaatc
    30181 cagttcgtaa cgcggataat gactaaccgt atggtaggcc atgacgtaaa aaagtgtata
    30241 aatagtaaag cttgctgcaa tctgagtcgg tgcaggcaac tcaatcgctt gatacaggag
    30301 aaatagccag atagctgcaa ataagtactt tttcccatcc atattgataa aaccttgcgt
    30361 cttttcgtga aaattgaccg tggtattagc aggtacaagc catgctgcac tcagccctag
    30421 caaaacactt gaaaaataaa ataaaggaaa ataaaatacg cctaatattc caagcaatga
    30481 accagcacca ccaatcagca gagcgatcat cagcaacgtg taactatcta gaccaaatcg
    30541 tagactgttg actaaaaata gtccagtcat ccgaaaggca taaaacagcg taaatggcaa
    30601 aatcgtcagc caattatgcg agtctgttag tcccaaaaat aaaagataag gaataaaaat
    30661 aaccgtgtta cttaagataa agggcgttgt ttgtgtaaaa ttacgcccaa atcgtttgag
    30721 tttttcgaac atgacaatgg ctccttaaac agtcttataa ctaatctgct cttcgatttt
    30781 agcattaaag gggaaataaa ccaattttac agaatatatt cttgtaaaaa aaaatacaga
    30841 aagaagcata agcttctttc tgcattttta cggtacttga ttactcaagc agacaagccc
    30901 ttctccacaa aagtcttgcc cgacacccct gcatccggca ggtgataaag atagaaatca
    30961 attatcctgt gcctccaaaa tcaattagga gctctgtaaa ccagagtcct tctcgacccg
    31021 tcgcataaat ttactttaac acagttccta tgtttatgcg agagcttttt tcattttata
    31081 atcgaccatt tgaaatcctt gaccgatatc tgaaataagt tcttctgtaa tctcaaatcc
    31141 ttcatgctta taaacctcga ttgcttgatg attcccctga ttcactcgca aaaagatctc
    31201 tctttccttt gtttgcgcag caagttcttc ataccagcga aaaactgaag aagtcaatcc
    31261 ttgaccacgt actttattta gcaaatataa tttacttaaa taaatttttc catttatctc
    31321 ttcataagca gtgtaaccga cagtcttttc ttcgcttttt aataaaaagt aggacacacc
    31381 ttctgtcagt tctttttgaa tctgtttttt tgactgataa gttttcagca tgtaatccac
    31441 ttgtttttga ccaatgatcg gcacaaaaac ttccggccat acttcttgta tgactgccat
    31501 cagctcatcc agttcatttt ctgttacttt tattttttcc atacacccac gtcctttttt
    31561 acattataaa tgaccttgcg cttgatggaa taaaaagagc atgatcatgc tatacacacc
    31621 caccgaccac ggtttcaaga aaatcacaat ctgcataaat tccctaaaag ataatttcgt
    31681 caaaccagct actagacaga tcaagtcgtc tggcgcaaag ggaagcagca aggtaacaac
    31741 tagtactttt ttaatatctt tcgtttttct tgtcagcaat tcatcaaatt tctgatactt
    31801 ttttggcgat aaaataagct ggacaaaggc tacgccatag taacggacaa gcaaaaatcc
    31861 gattgcttcc ccaatcacta ggccaataca actatataaa agcccaaatc cattgccaaa
    31921 catcagcatg cccgctactg aggagatccc tcccggcaaa ataggaatga tcacttggat
    31981 cacttgcaac agaacaaata tcatcactgc atacttgcca aattgctgga taaacgcttg
    32041 caaagacgtg ctcgatcgaa aaatcccatg atgataagca taaagaatca acacaaagaa
    32101 aaaaaacaga ccaataatgg gcatgatctg aagacatttt tgtaaaactg atcctttttt
    32161 agacatctat attccccaca tcttttttca tttattaaaa ctgcctcctt atgaactgaa
    32221 ccccaaaagt tgaactattt aatggactgt ttccgatatt ctactggaga tagtccattt
    32281 aactttagtt ttatcctttt gttattatac cacctaatat actcatttaa tttactttga
    32341 aatatctcaa ttgatcggaa tttttctcga taaaaaaact ctgatttaag cacaccaaaa
    32401 aaattttcta ttacagaatt atctaagcaa tttccttttc tagacatgct ttgaataatg
    32461 ttattctctt ttaatttttt ttgatattgt ggcatctgat actgccatcc ttgatctgaa
    32521 tgtagaatca gtgaaccctc agttcccttt tttttaattg cttgttgaag catttcttca
    32581 atcagtttat atgttggact agttgatata ctataactaa ttatttctcc gttaaataaa
    32641 tcaagtatag gagatagata gatttttctt ccttttatct tgaattcagt gacgtctgtc
    32701 acccattttt tattgggtgt atctactgaa aaatttcgtt ttaacacatt cttggcaatt
    32761 tttcctactg ttcctttata agatttatat cgctttattc ggatttgaca ggtaagtccc
    32821 atttgggaca ttaattttct aactgtttta tgattgattg tatatccttt catctttaac
    32881 gctaaagtga ctctacgata accataagag tttcttgatt cttttacaat cgctgtaatt
    32941 tcttgcttta tcttgctata tttatctg
//
LOCUS       DADQCX010000023        32879 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.023, whole genome shotgun sequence.
ACCESSION   DADQCX010000023 DADQCX010000000
VERSION     DADQCX010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.023"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            403..2040
                     /locus_tag="J8R83_001030"
     CDS             403..2040
                     /locus_tag="J8R83_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAZ9574173.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2185..2925)
                     /gene="truA"
                     /locus_tag="J8R83_001031"
     CDS             complement(2185..2925)
                     /gene="truA"
                     /locus_tag="J8R83_001031"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAZ9574174.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3116..3751)
                     /locus_tag="J8R83_001032"
     CDS             complement(3116..3751)
                     /locus_tag="J8R83_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAZ9574175.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3898..5139)
                     /gene="sstT"
                     /locus_tag="J8R83_001033"
     CDS             complement(3898..5139)
                     /gene="sstT"
                     /locus_tag="J8R83_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAZ9574176.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5337..6335
                     /locus_tag="J8R83_001034"
     CDS             5337..6335
                     /locus_tag="J8R83_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574177.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            6348..8366
                     /locus_tag="J8R83_001035"
     CDS             6348..8366
                     /locus_tag="J8R83_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAZ9574178.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8426..9142)
                     /locus_tag="J8R83_001036"
     CDS             complement(8426..9142)
                     /locus_tag="J8R83_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAZ9574179.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(9369..9911)
                     /locus_tag="J8R83_001037"
     CDS             complement(9369..9911)
                     /locus_tag="J8R83_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAZ9574180.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9916..10143)
                     /locus_tag="J8R83_001038"
     CDS             complement(9916..10143)
                     /locus_tag="J8R83_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAZ9574181.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(10222..12102)
                     /locus_tag="J8R83_001039"
     CDS             complement(10222..12102)
                     /locus_tag="J8R83_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAZ9574182.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(12291..12905)
                     /locus_tag="J8R83_001040"
     CDS             complement(12291..12905)
                     /locus_tag="J8R83_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574183.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            13047..13607
                     /locus_tag="J8R83_001041"
     CDS             13047..13607
                     /locus_tag="J8R83_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574184.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(13912..14226)
                     /locus_tag="J8R83_001042"
                     /pseudo
     CDS             complement(13912..14226)
                     /locus_tag="J8R83_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(14480..16115)
                     /locus_tag="J8R83_001043"
                     /pseudo
     CDS             complement(14480..16115)
                     /locus_tag="J8R83_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16670..17233)
                     /locus_tag="J8R83_001044"
     CDS             complement(16670..17233)
                     /locus_tag="J8R83_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAZ9574185.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(17248..18291)
                     /locus_tag="J8R83_001045"
     CDS             complement(17248..18291)
                     /locus_tag="J8R83_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574186.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(18424..18828)
                     /locus_tag="J8R83_001046"
     CDS             complement(18424..18828)
                     /locus_tag="J8R83_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAZ9574187.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(19061..19696)
                     /locus_tag="J8R83_001047"
     CDS             complement(19061..19696)
                     /locus_tag="J8R83_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAZ9574188.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(19962..21014)
                     /locus_tag="J8R83_001048"
     CDS             complement(19962..21014)
                     /locus_tag="J8R83_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574189.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(21027..21965)
                     /locus_tag="J8R83_001049"
     CDS             complement(21027..21965)
                     /locus_tag="J8R83_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAZ9574190.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(22416..23066)
                     /locus_tag="J8R83_001050"
     CDS             complement(22416..23066)
                     /locus_tag="J8R83_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574191.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(23166..23675)
                     /locus_tag="J8R83_001051"
     CDS             complement(23166..23675)
                     /locus_tag="J8R83_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAZ9574192.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(23876..24745)
                     /locus_tag="J8R83_001052"
     CDS             complement(23876..24745)
                     /locus_tag="J8R83_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9574193.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(24765..25886)
                     /locus_tag="J8R83_001053"
     CDS             complement(24765..25886)
                     /locus_tag="J8R83_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAZ9574194.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(25888..26283)
                     /locus_tag="J8R83_001054"
     CDS             complement(25888..26283)
                     /locus_tag="J8R83_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAZ9574195.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(26302..27099)
                     /locus_tag="J8R83_001055"
     CDS             complement(26302..27099)
                     /locus_tag="J8R83_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9574196.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(27101..27889)
                     /locus_tag="J8R83_001056"
     CDS             complement(27101..27889)
                     /locus_tag="J8R83_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574197.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(27903..28379)
                     /locus_tag="J8R83_001057"
     CDS             complement(27903..28379)
                     /locus_tag="J8R83_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9574198.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(28451..31108)
                     /locus_tag="J8R83_001058"
     CDS             complement(28451..31108)
                     /locus_tag="J8R83_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9574199.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(31127..31531)
                     /locus_tag="J8R83_001059"
     CDS             complement(31127..31531)
                     /locus_tag="J8R83_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAZ9574200.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(31763..32020)
                     /locus_tag="J8R83_001060"
     CDS             complement(31763..32020)
                     /locus_tag="J8R83_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAZ9574201.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(32145..32477)
                     /locus_tag="J8R83_001061"
     CDS             complement(32145..32477)
                     /locus_tag="J8R83_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574202.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT        10378 a         6491 c         4965 g        11045 t
ORIGIN      
        1 gaaattccat aaaaaacgac tgcaggaatt attgtaagaa aaggataaaa atagttcagt
       61 ccatctccat aattgttaaa tgttgtatag ttgattggcc cttcaaaaat agaagataac
      121 cctttgattc gtgaaagatg aaaagataaa tcacctgttg tataaatttc ttgagcattt
      181 ctcataaaat ttactgaata taaagtacta agtaagataa gaactactaa aagaaatgct
      241 tttttactta ttttcataga tttgttgttc tcctttttta attctatttt cagtatacta
      301 gaattgtctt tttttaataa gttttgcgtt aaatttttca tagcactagt atgatatact
      361 agaaaagaat caatttttat tacttttaaa taggagaaaa aaatgaaaaa aaacaaaaac
      421 caaataatag atatcatttt tatgttattt ctaagttttg cttacgtcat ccctctattc
      481 atgtctaagg gaatctatca tagtgtcaat caggatactt actttcattt atctcgaatc
      541 ataggactag ataatgtatg gagttctcca gtaaacttca ataacttcga tcatcatgga
      601 acaatgatga atatttttta tccatggctt actctttatc cagctttttt attttataaa
      661 atgatgggaa atcttgtttt aagttataat atctactatt tttttatcac ttttttaaca
      721 atggtcgttt cttatttttc tatgaaacaa ataaaaaaca atcgttatat ttcgctgtta
      781 ttttcgatta tttatacatt ttccgcctat cgtgccattg acatattcca tcgtgcttca
      841 ttgggagaag ctgtcgcttt aacatttttg cctttgatac taatggggtg ttacgaaatt
      901 tatattagag attaccaaaa atggtactgg ttgtctattg gcatgacgct agtagtgtat
      961 actcatttac tttctgtcgc tatggtttct gtatttattg gaggaacgtt gtttctttct
     1021 ttttattttt gggaccaaaa aatcgctaga ctcttaagtc ttttaaaagc taccgtcctc
     1081 accttttttt taagtgcggg attcttaatt ccttttattc aacaatctag agcacaagaa
     1141 ttgaaagtcc cactgggaaa agaattaagt ggtatggctc ctagtgatat gctgacacat
     1201 attttaaata ataactataa caactatact attggattat tcttatttct cggattgatt
     1261 ggtgctttta tttttataaa aaaattaact gctgatgatt tatttatttt ctttcttggt
     1321 gtatttgttc ttttttgttc aaccaattta tttccttggc aactttttaa ccatacacca
     1381 gttaagagtc tacaatttgt ctggcggtta aatggttttt cttctttatt tatagcctat
     1441 acgatgagta tagtgatcta ttatattttt tctactaaaa ataattcatg gaaaataatg
     1501 gtctttacgt ttcttgcact aatattgcat ctctcaggag taagcaattc tatccatgct
     1561 aacaaagatt cattaacact tatagcacct gaagacgctg ttgctatagc tgaaaattac
     1621 aatcatactg attatgcaaa caaagagtca atctatcatc ctgatatgat taataatgat
     1681 caatatttac taggtaacca ggaaataaat ccaacaactc attttatgag taacaaactt
     1741 acaattgaat tagataattc gaataataaa aatactgtct tgacgacacc tatttatcgt
     1801 tataaagggc aagtggcttc tattaatggc aaactagtac aaacaaaatt atctaagttt
     1861 ggcacaactg aattaactat tcctccaggt ataaataaag tcgttattac ttatcagtac
     1921 acaaaactag caattgcttc aagatattta tctatcgtta ctttgatttt atttttactt
     1981 tatcgattta ctttttctaa acaaaaacaa ccgagaagag aagtacaaca ttctcactag
     2041 atttttattt aagaaagact ttttagctgt acacataaac aggctaaaaa gtcttttttt
     2101 atatttcttt aatttgcttc atacattatt taacatcgat atttatactg tgaaacatgc
     2161 gtttcatcca ttatcaaagt atttttatcg ataataaact tcatccaaaa acagaccttg
     2221 tgcagggacg gtttctcctg catgttgccg cactttgctt tcaaatattt catcgattgt
     2281 ttctatcggc atggcacctg tgccgatttc tagtaatgtc cccatgataa tccgcaccat
     2341 tttatataag aatccgtctc cgacaaaagt aaaatgaagc atttctccct ttcgttcgat
     2401 agataattca tcaatcgtac gcactgtgga tttttttgat tttttcaatg cagaaaaacc
     2461 aatgaaatca tgtgtaccca ctaatttttc gcaagctgca ttcagcttgt ccatatccaa
     2521 ctcttgaggg aaataaaagc tgtggtttcg ctcaaatgct gaaggaatca cgttgttcca
     2581 aacataatag ctgtattttt tgcccaccgc attatatctt gaatggaagc gctcaggcat
     2641 ttcttcgatt cttttgatga caatatcccg cggaaggtaa cgattcataa agtcgatcat
     2701 ttctgccagt ccaatttctg tgtttgtttt aaaatttgct acttgtcctc gcgcatgggt
     2761 gccagcatct gttcttcctg atccaataat ttctatctct tcatttgtca tctgatgcaa
     2821 tactttttcg atttttcctt gaatggtttt atcgtcatct ccaagtcttt gccatcctga
     2881 atatcttttt ccgtcatatt cgattgtcaa cttgatgttt ctcatatttt agtggctcct
     2941 ctgtcttcca tttggtcttc tctctacctt tttaagattg tagcacaaaa tatagctcct
     3001 tgcttctcta agacagaagc tatacaagaa aactgtggaa atatatattt cagaaaaaca
     3061 aaaaacagcc accggatgaa gtatccgctg actgttcaat ttgacggctc aagttttact
     3121 gtttgagatg caagatactc aaccaggcaa tgggcacata attaaagaaa aaactgattc
     3181 tttggcaaaa acctatttta ttcagtaatg gccaagaatt tatagaagga attcttgcca
     3241 gtccataaat cgccgcaaaa agcaaactga tcacagacag tccaaggtat aagtggctta
     3301 cgtccatttg cccatttttt cgatagatca agaaaagaag aactggaaac aataaaaaac
     3361 cactgtaacc taaacctgat ccgatattat ggacccatgt cgagacattc cacgaagatt
     3421 catgggtatt gatactgaac aaacctgtaa agatacaatc acctatacca tagaacgcga
     3481 tggctgctgt aactagggta gctaacacac gagatgtact aacaaatgca gcatacaatg
     3541 caggcaatga caggatgaaa aagatccctg aaaccacaga ccaaataaga aacgcttttc
     3601 ttacaggact ggaaacctct ccaaatacac tgatcacgct cttcatttga tctaattcag
     3661 gataatacaa tcctaatacg tacggagtca aaaaatcact cagcacgcct aataataaaa
     3721 agaaaaaacc aaatttacgt aaaaaatcca tgatacgcct ccaataacaa ttacctatgc
     3781 ttttaattgt tattataaac gactttatct tgatttaaca gaaacctcta tttacacgaa
     3841 catctatata actcattaaa aactcgaatc attttaaaaa tactaaatat ctaacgttca
     3901 acgttcactt aatccatcta aacaatcttt caatttgatt ttttccccac ttcttttacg
     3961 cgcgcctagc tctcctattg cagtaaacaa cagatcactt gacgaattta aggcagtttc
     4021 cattgaatcc tggataacac cgataataaa tccaataccg acgatttgca tcgcgacatc
     4081 attagagata ccaaacaaac tacatgctaa tggaatcaat aacagtgaac cgcccgcaac
     4141 acctgaagct ccacaagcag ctaaagcaga caaaatacat aaaaggactt tcaaaacaaa
     4201 aggtgcttca atccctaaag aatgtacagc agtcaacgtc atcaaggaaa tggtaatcgc
     4261 ggcaccgccc atattgatcg tagcacctaa cgggatcgat atggaataag actcttttgt
     4321 caatttcaat ctttcagcca acatcatgtt tatcgggata tttgcggcag aacttcgggt
     4381 aaagaaagcg ggaagtgcgc tttctttcaa acaaaagaaa atcaatggat agggattttc
     4441 tttaataaac aaaaacgtga ggaatgggta cacaactaat gcgacaaaca gcatcgtacc
     4501 gatcaaaaca agtaaaagct gcagatactc tgccaatcca gcgattccag tcgtagcaat
     4561 tgattgataa accaatccta aaatccctat cggagcaaat gcaataatca cttgtacgac
     4621 ttgtgacaac gctatagata tctgatccac caactctttt gtcgattctg aacgtgctcg
     4681 aaaagctagt cccaacaata cagcccagaa taagacgcca aggtaattcg catcaataag
     4741 agattgaaca ggattttgtg tgacattcgt caacatagta gataaaacac tttccaaact
     4801 ttgcggtgct ttttcagata ctgtttcttg taaagtaata ggaacagtaa aaattgaact
     4861 tacaataact gctacaagtg cagaaagcaa tgttcccact aaatataaga tcaaaatagg
     4921 cttcacgaat gtcttattcc caattttatg cttggcaatt gacgccatcg tcaagaaaaa
     4981 aaccagaata ggtgcgattg ccttcaagca actgacaaac aacgttccca atattgaaat
     5041 aaatgtccat gtggggaaaa agataccaaa caatattccg actaaaatac caacaacaat
     5101 acgttgaact aacgacatat ccaaaaactt ctctaacaaa tgaccaccct ttcacaattt
     5161 taacaatcat tgtatcattt tatgcaaaga aactaaaggt ataattttct aaaaattcta
     5221 acaatacaaa caaccatttc ttgctaattt tgtacttttt ctgtctacac gttgtttttt
     5281 gagatattct aagttaggat gttattaatg ggcaacttat caggaaacgt tttcttatgt
     5341 ttttgtccaa tttttttgtg aggtgtttat tcttgaaaaa aataaagaag gagagttatg
     5401 gcttcctgac aatctttgtc gcttgtataa tgatggtttt acagcgtata ttgatttcag
     5461 cagtcactat tcctacatat gcaacaaacc ctggtcgatt ctacatctat acatttttac
     5521 aaacttccgt tgttattggt gcaaatttga tcccacttta catgggttac caatatcaaa
     5581 aaatcgcccg tttaaaagtt ttacattatt taagtcgttt tgcctttata ttcctaatag
     5641 ccacactagt ttgcaatatc tttttttacg tacaagctgg cagcttgaat attcgtgatt
     5701 attggcttat cctaacacct atcagtcaga attactttac ttatgctgtt tcttgtactt
     5761 tgcttttttg tagtattcct tatacagttg gatttttaaa taaattatcg aaaacaacaa
     5821 ttaaatatct actattattt ttaacaattg gattagttgg ctgctctact ctatttaata
     5881 aagacccgtt tgcattacag aatggacaga gtattttatg gattttttat ttatttttaa
     5941 tgggttatgg tttgaaagaa tggaactgga aagaaaaggt ccgctataag cttcctcaag
     6001 tatttatcag cttgattgtt ttattcggtt tgattatttt gatgacacaa atttcactca
     6061 tcatcagagg aaatacagat acagcgctga ggttttctaa accatattct ctcttcgcaa
     6121 tgtattatac tttctcttcg tttttatttt tagaaatgct atctgataaa ttaggtataa
     6181 aaggaagagg aaattttctt gctgtatttt tgattgtcac tcaagttata tgtaatttcc
     6241 ctttagtttc ttatcgcgta tctacattta tgaaacgtga atttccaaac tcagggaagg
     6301 catggctgat aaatatcggg cagtttttta tttgatattt attagcagtg tccctcctag
     6361 ttatcttttt attttatata caaaaaatcc gtttcattca tcgtttcatc gaatacttcg
     6421 cttttgattc gattgaacaa ttaactcagc gttggaaaaa aagaattcat tggctttttg
     6481 ttcataaaag ttatttttta gttgcagcat ttttttactg ctttaccttc gtgcagattt
     6541 tcgttttaga accaaaagaa ggttggaaag aaactatcca ggttgcctta aaaatattta
     6601 ctcagcgaca agcacccatg atcctgacaa tcatcattat tatgggattt ttcttcttac
     6661 tattgttgat ttccaatcgt ttttggtacg ccttgactgc taccttgatc attaacttac
     6721 tgctcactat ttcgacagta atcaaaatgg aaatgcggga agagcctgtc tttccttcag
     6781 atttaaaaat gctgaccgga ttgtcagaac tattatcgat ggttagccca gtcttattaa
     6841 tcgtgggcgg attgatcctt ctcctattat tgattactag tattattgta caacgtagac
     6901 tacaaaaaca gtattccttg aagattcatt ggaaacgtcg atttatcagt atcgctgtat
     6961 tattaggatg tttttcgggt gtctttttca ttaatcacaa aaattcgcct tctttcttgc
     7021 tgtttaattt atttaaagta aacaagactt tctttaacca gcaaggcgcc gtaaaagata
     7081 acggaccagt cattcaattc ctaaacaata tcgacattaa aatcatggaa gaacctgctg
     7141 gctattcgaa agaaaaaatt aatggaataa tgaaaaagta caacacaaag gcagatgaaa
     7201 tcaaccaaac aagaagtgac tggttaaaca atcagacgat cgttctcaat ttaagtgaaa
     7261 gcttcagtga tcctgcacgt gtccctaatc tgacagtacc tacagaccct attccttaca
     7321 tcaaaagcat tataacagaa ggaacaggag gattgatgtt atccgtcggt tatggtggcg
     7381 gaacagctaa catggaatgg gaaggactga caggcttgag tatcagtaac ctgtctgctt
     7441 cgttagttac accttatacc cagctagtgg agcgtcagaa aataagtcca aatattaccg
     7501 atctattcga tgaaaaaata gccatccatc cttttacagc tgctctttat cgcagaaaac
     7561 aagtgtttga taaatttggt tttgacaggt tctattattt agacagtccg gataaattaa
     7621 cttatacgga taaaatagaa caaagcccac gcatatcgga tgattcagca tacaaagaaa
     7681 ccttgaaagc tttacaaagc aatacggaaa cgtcacaatt catccaatta tccactatgc
     7741 aaaaccatat gccttatgat gattactata gtgaattgaa ctacactgct gaaggaactg
     7801 ctgtcattcc taatagaaga aaagaattac aaacttatat gcaaggcctt cactataccg
     7861 atacagcagt aaaaaaattc atccaagaaa tcgacaaaat cgataaaccg attacctttg
     7921 ttttttatgg tgaccattta cccgcaatct atagtgggaa tgattcgaaa aaatatggat
     7981 tagaacagca ccagacagat tatttcattt ataacaacaa gtatagtcgt gaacaagcag
     8041 ctacgttaaa taaagaagtt gttgctccta ataactttgg tgctatggct cttgagcatg
     8101 cgaatatcaa agtaactcct tactatgcgt tgttgacaga agtatctaat catctacctg
     8161 cattaacaat tgatcctaca gaaagcttgt ctaatcgttt taatggaaaa caggtctttg
     8221 ttacagagga tagtcaaatt atccaagaaa aaaatttaac tgagaaacaa aaagaaattc
     8281 tagaagatta tcgtctgata caatatgatc ttgttgcagg taaccagtac agtgcaacat
     8341 gggcgacaca aaaaataaaa gactaacaaa taaactgagc aaggggttgt gataaaagac
     8401 atgtcacaac cccttgttta tctcattaat ttgcttgtcc ataaacgatt tgattaaagc
     8461 catttttcaa ttcattattc gctgtctcgt tgaagtaaag ataattatcg ggattcccct
     8521 gattttgttg tgtcaccaat acttttggct gattttgctg aaacccgaat agatagacgt
     8581 gctttttcag atatggttct gtctctgcat cggaatagac ggctgtgatt tgatagtctg
     8641 cttgacctgt cccactttct gaccattctg cagaaacagg cactccacca atagccatct
     8701 tccactcccc gttcaaaata gcttgaggga ctttaagacc atataagtcc acactcattt
     8761 gattcgtata acttttgtat tgttgtccca ttgtttggcc ccatttggtc ataaatgcct
     8821 ctaattgtgc ggatttgtct gcattccaca gtgtttgttc aacttgttcg ctgctttctg
     8881 aagaggaaga tgaagcctct acagaagaac ttgaagtaga tgtttgagtt gtttcagtcg
     8941 ttttggaaga ctctgacgaa gtagaggtat ctgctgtttc tgtacttgct gcagttgact
     9001 tgctctctgt gctagttgtt gtagtagttg caactgttgc tttcgctgtt tcttttgttg
     9061 attctttttt cgattcattc ccgttggtac aaccagctaa caaaaaagct agaccaattg
     9121 ttactaaaat cctttttttc aattaaaaaa ctcctttcga ttactcccac ttctttattc
     9181 tatcaaataa gcaatgtgat tttattgatt tttcgtattt tctcatcaat ctttcaaatc
     9241 ttctaaaaac tgagaagcac ccgctgatgt tgtctgtaat acatcagcgg gtgcttcttt
     9301 tattttaatc ttcgtgattt tccaatttac ctcacgcttt atatttgtat ttgaagaaac
     9361 atagactttt agtcatcatc gtcttcctca tccaaatctt gtcggacagt ttttccttgg
     9421 agtctttgta cttggtagat gatttcttta ttgaaactta aaagttcaac aagcaattgt
     9481 tgcaagccat atttttcttc tttttcagct aatttgattg cccgtgtgat aaagacattt
     9541 tggaaatcaa aatcttttgc aaagttttcc aacattgttg aggctggtaa atatttgttt
     9601 tgaccatgtt cgtaaatttt tccataacgc atgacttctt ctaaagtaga cggaacgatt
     9661 tcattttcaa tcactaactc atgagagatt ttattgaacc atctcgcttc ttgatcagca
     9721 tattctgaaa aaagggtact taattcttgc gaagatgtac ccaaaacata caattgtgct
     9781 tggatcaatt tcatttcttc taatttaaaa tttgctaata catgccccac catggcgcca
     9841 gcagttggtt tatgatggtc gatatctgct tgttttgttt cttgaacaaa tttttcttcc
     9901 actatattca ttgatttacg cctcttttac ttttgctgat tggacttcat aacctaattt
     9961 ttccacaact gcagctaatt gttcagggtg gacttcatct ggatcaaagt ttgctttgat
    10021 tttgctcgca ttaaacaaaa ctttcgtatt gcttacccca ggctgttgag aaaccgcatg
    10081 ttcgattttt tgcatacagc ttggacaagc tagtgtatct aattgcataa taattttttt
    10141 catcgtagtt cttccttcct ttttcttgat agtcttattc tagattacag cttccataaa
    10201 aaaattgatt cttatcaagt tttacgattt ttcttctttg ctttcgtgtc caaaatacaa
    10261 taaacgcatc gcgttaaaga taacgatcaa gatactagct tcgtgaacga acatcccact
    10321 agccatgtaa ataaacccgg caaataagcc gttgagtaaa aataagacga caccaatggc
    10381 aatcactaca ttttcacggg tatttaaaac agttttctta gccaagcggt aggcatgaac
    10441 caacgattca aaattagatt gcatcaagac aacgtcactc gtttcgatag caacatccgt
    10501 tcctgatccc atagcaatcc cgatatcagc cgcagccaaa gagggagaat cattgattcc
    10561 atctccaata aaagcaacgc gcaatccttg ttcttggtat tttttcacaa attgaacctt
    10621 ttcgtctggt aataattcag catggacttc atcaatgcct aacatatcag ctacataatc
    10681 agcagtcatc tgattatcac ctgtcagcat cactaactgt tttgctcctg cttgtttcaa
    10741 cttagctaat tgttcagcga cttctggtcg aatcacatct gacacaccta tgatttgagt
    10801 gatttttttg tcgattgcta caataatgac cgagctgcct gtttgttgta attgatgtaa
    10861 atcttgtact tgctttggtg tgagagaaag tttgtgagcg gcaatcaatt tggtgttgcc
    10921 cgcacaaact gtatgaccat caatctcagc tgtgattcct tgtcccttga ttgtctgatt
    10981 atctttgact gctaattgtt gaaaatcaat gtctttctcc tgagcataat ggatcacggc
    11041 gcgccccaga ggatgatcgg ataacgtttc taatcgagcc actaaagcta agctgtcccc
    11101 ttcatcctct gtatagttct tgatagtgga tacagcagta gttcctttgg tcaatgtacc
    11161 agttttatca aagacaaaag tatcgatttt ggaaaaagta tccattgctt caccgccttt
    11221 gactaagatg ccccgtttcg ctccattacc gattcctgct acattcgaaa caggcgcacc
    11281 aatgactaaa gcgccaggac aaccaagaac caaaacagtg attgctaaac gaaaatcacg
    11341 actaatcaga ccaacaacca acgcaataag taaaacggtt ggagtataat actgagaaaa
    11401 tcgatcaatg aatttttccg catgggattt ggtatcttgt gcttcttcta ctaattcgat
    11461 aattttggca aaggtcgtat catctccgac cttagttgct tcaatcgtca cgtagccatc
    11521 tgctaaaatc gttccagaga agacttcatc tccactgatt ttgacgactt gtcgtgattc
    11581 accagtcact gcggcttcat ccgcataccc tttcccgtca atgactcgtc cgtccacagg
    11641 aatagctcca ccagttttta ctaagacgat atcgccttct tccacgtcat cgatttccac
    11701 ttcttcagtc gttccatctt cttggacaac actagcagta gatggggcca tctcggtcaa
    11761 agccttgatt gactcccgcg ttttggtcaa tgttttttgt tccagatagc taccaaacaa
    11821 aaacaagaat gtaacgatag ctgactcctt gtattctccg atcataaagg caccaagcac
    11881 agcaatagta acgagtaaat caattgagat aactttgact ttcactgcct gatacgcatg
    11941 gatcataata ggtatgaccg caataataga agctatggct agagcaatgt tatagaacaa
    12001 gacaaaacca gtaaattttc cgataaaacc aaaaataatc aacacagctg ataaggcggt
    12061 gatatgattt cgatgctctt ggatccactt ttgtaatttc atctttctcc ctcttttcct
    12121 ttcattctta cgagactaag tatagatact tatccatcat aaaaaattga ccactatcaa
    12181 gtttagtcaa aaaggcggtt ttcttttggt agaatacact acaaaaaata gttagcaaga
    12241 agactcacta aaagtgatct tgccaactat tgtcgtttct atcgaaattt tcattgaatg
    12301 attttcctgt acagcataca tcggagatct atttctttat ctaagatttt tatcttgcta
    12361 attttttcct ttagtctttc aaatccacgt cgttcataga attgatacgt acagccacta
    12421 tctgtaaaaa ggaatatttc ttttcctttc tctctttttt caaattctgt tagcaacttg
    12481 gtaccgatgc cttttgtttt caaatcagga tttgcagcta aaaaaatgat ctctccatct
    12541 ggcgaatgct tctttaaata tgctgcaagc atttgttcat ttgctgtctc gtaagctcct
    12601 ttactttctt tagcaaatat attttgtaaa aaatcgaata tcttaacata tatttgctgt
    12661 ccaaaagaac gatgtttctt tttttctcct tttatctccg ccagcaaaac acctgccaac
    12721 tcgtcctctg catacaaagc aagaatttga gttgctcgat tcaactccat atacaaaaaa
    12781 tatcttccgt aaagattcag cagaagttca ttttccatat atctctcaaa gttcattcct
    12841 tcaacagcaa aatagatagc ttttttgtaa tctttctttt ctaagggttt aaaagttagt
    12901 ttcatcattt cgcctcctca acttcaatga ttgtgttata cttacattat aatagacaca
    12961 gtgtctacta tctataatca atcatctata agtttgtcga ttaagcgaca gctttgcttt
    13021 gatatgtcgg ataaggagat aggtaaatga aaaagacaga tagacgcgtc aaaaaaacag
    13081 aaaaagcttt ggctgaaaca ctatccacat tattagtaaa taaaaagatt caagcaatca
    13141 ctatacgcga actaacagaa acggcagatg tacatcgttc gactttttat acacattata
    13201 aggatatcta tgatctatat gatcaattag aaagcaactt ttttcgggat ctaaatgaaa
    13261 ttctctctta tgatccagcc catagctatg aggaactata cactcgcttg attgactatg
    13321 tttacgcaaa tactttttta tatcgcttat ttatcctcaa ccatggtgat atttcgtttc
    13381 agaagaaagt taaacaagtt attgaagaaa actatctgaa catatggcta tatgaagaca
    13441 agaaaacgat tatcacagaa gaaatgagat tctttactac gtaccacgtc caaggttgtc
    13501 tatccgttct caatcggtgg gtagaaagca attacaagta ctccaaaaaa gaattattag
    13561 aactcttaca gaaactgaat gatcacatag agaaaatcat gccttgaata aaaacatact
    13621 aagcttagtt aagaagaacc gtaaccttct cgtataacaa ctgaatctta tttagccaaa
    13681 ttgtttactg aagatttttt gagtaaaatt tctataattc ctacttattg aaaagtagtt
    13741 tgtagtgctg cttctccctc tctaagtgat atatcttgtt gtaccaatca aattcacctc
    13801 atcattaata aattactttt aggctaattt attacaactt ataggttgaa gctgtaacca
    13861 atttatagtc atattatatt tttatcatcc agtttattga attcttctcg tttacctcaa
    13921 ttcattttca aggggaatca gctcatcatc taacatttta cgccatgctc gcttcatttc
    13981 ttgtgggtat ttaaatggtt tcgcttctgg atgtttggct ttatatcctt cgtaatcctt
    14041 actgttgata attgctttca tattaggaat tggatcttca cctggcatat attgcagatt
    14101 agaagcatgt aattttttct cagaaacaaa ccactcattg gaaaagacat gaatcaaatc
    14161 atcacttact tgtgtaaaat agcgacgttt aatgacaaag atatcttcat tgctatctag
    14221 tgtaccttca tttctttgtg cttaaattca aagataattt tctcaataaa gatttttgat
    14281 tccagtaaga ttcctttact ccttttacaa catagcgttg tcctttgttt tgaaacatct
    14341 tcttcccctc tttgccatta aaaatagccc aattctctat aaagaagatt aagcttcatt
    14401 attataatat aaagtttaaa tttggtttat tacttacttt ttcttattct ctagtaagct
    14461 aatattgaaa aaaatgtaat cagatcatta tttttatatg ttgtaacttc ctgataagaa
    14521 aactaattaa aagaaagagg taactacata aactaattaa aaaagctaac ttcatagttg
    14581 gaggataaat ggaagaaact tcaatgattg tttctccttg tgttccttca atcgacacta
    14641 gtcctattat caatctctct tttttgtcca tttacttttg cgactgttcc ccaataatca
    14701 aatacaggaa gcgttatttt ttgtccttta gattcatgta ctgtatagac tattttcgaa
    14761 tccatcactt gataaggcat agtatgccat tccttgccaa ttcttacttc atgattctgc
    14821 aaatgttctt tgtattgtaa tgcttccgtg ggtgcatagt cataaagtcc tccgggaagg
    14881 agtgtcgtgt aacgaataag attttcttga ttcattacca agtgatctct ctgagtgaca
    14941 actttatgtt catagtttgc ttttgttgca gcagatacag ccaacagtaa taaaacaatt
    15001 gccgttatat taactacttt tctttgctta gctgatgtgc tcttcatgaa aacgaacgat
    15061 aaaatcaacg agccaaacag tacttgaaag cctaagattc gccaaggaaa ttgaatcatt
    15121 tgaatgggtg tattttgtaa taaagaccat ggaaaaaatt tggtggataa gagccaagag
    15181 actaccgcac taaggtaaat cactttttct ttgcgattaa atcctttaaa aaagaagagt
    15241 ggacagatca aagaaataat accaatgatt cctaccgtaa aggttgtcag gtcattattc
    15301 atcgcaccaa tcaaactatc cgagacattt aatgcttggt gttgtaaggt cgttttatct
    15361 ggctcattaa tcgattgaac catgatttgt cggaacatcg gataccaaaa gtatgctgtt
    15421 aaaagaatcg tcattcctac tgcctttgac aactccacaa tcaaccggat gctttctttt
    15481 tttcttgttt cacttactac aaagccgcct aagactagta agccaacggc tattacactc
    15541 ataaaagtgg aaagaacatg tgtataaatg agtaagctca tactgactgc taatggaatt
    15601 gcacatggct ttttctcata aatcagtgcg taagcataat acataactat cggtataacc
    15661 gtaagtgcaa tcgcttcagc aatagcagaa cgatgataaa tatcaatcgt acggtaccca
    15721 taaaatgtat ataaacagct aaatataaaa gccgcatcga ttctttttaa aaattttagt
    15781 ccataatgaa acatcagcat gatagtacaa acattcaata gccaaacata taagatataa
    15841 ctaacgatta aattattact tatccaataa aaaatgactg ccggaaaaaa ggtcaagtag
    15901 ggataaaaat aattcactcc gctcccataa tgattaaacg tcgtaaaatt gattggacca
    15961 gaaaaaattg aagataaccc tttgactcta gcaaaatgga aggcaatatc ccccgatgta
    16021 gaaatagtat gaacatttct aaaataattg attgaataaa gtccagcaat aattgctagg
    16081 agaatggaca atattatttt tttctttact tgcattactt aattatatac tcctttcatg
    16141 gattgcttta tctagtataa cttaaatttt aaataaatcg ttatttattt ttactctcac
    16201 ttaaaaaagc actaaaatta taagagaggg aggtaatggt ctgaacacca agaattgttc
    16261 caacatcgaa ttgcttaact aatgagttca aagcttaatt atgtggctct tatatttacc
    16321 gagcgtggat tgcgatctct ttagcgaaac aaacatcttt cataaaaaaa acagccatat
    16381 ccgctttctt ggatatgact atttactact actttactat ctttcattct tcttgtctca
    16441 cttatgataa ggcgctgcgt atcatgagtg aatgatatta ggaaaacttc ataaaataaa
    16501 tcttttatac atttccactt ctagatggtc attcatgtta gaagaatcaa actatttttt
    16561 tactgtcgta ataatattaa aacactagaa caaatcaatt aaattccata aaatataaat
    16621 aatagaccta gcatcatctg gtataaaatg gatgctaggt ccgttatatt tactcaaaat
    16681 tgattctacg aatagatctt cttatcattt ctattttagt agtcatgcgt tgttgttctt
    16741 ctaaaggtgg taatggtata agtagtttag ataaatttgt accatttaca tttggttgcc
    16801 cagttccgta agaaattttt tctaataact tccaatataa tggcgagtct aagaagcagt
    16861 ctacgtattc tgataataat ttctcaacta acctaattcg aatcaagtaa gaagcaaaaa
    16921 cagattcctc acttatttcc ttaaccaaga aactttttcc catagttcct cctgtccttg
    16981 ctatcaaaat gtcattttct tccaatctta aatcaactag tttagaatta ctaatatcac
    17041 agtaaggcac actggaccaa tttacacgtc cctcttgtat atctgtgatt ctcaaaaact
    17101 taacattgcc ttgttttttc gccgaatctg tatagccata ttgaatctta gtagaaatac
    17161 ttcctaaata aacccatagt cgaacatcgc tagatgattt ttcttgtcgt tctttatgaa
    17221 caacagtgat catcttgagt tgtccgacta ttttttagtt gcagcaatct ttttgggacg
    17281 cttatttgca tgaagcaacg ttgctaagtc tagtaataaa acattggcta acacaggatt
    17341 ggctttctcg cgatacgctg cggcgccact ttcaaacaat actgctagac gatcttctac
    17401 aacaacgatt tgttccaaat acggtggaaa tttgattcgt tttaggatcc ggctaggaga
    17461 gtcccgctcg gacactaaga gttccgaggt ataaggacca taagaacgac tggctaagag
    17521 ataatggcca taaaaagcca caccttgaat cttatcagat gtttttctgc tcattgtcac
    17581 ggttggttgg attttgtctt tgcggcgaat tgctgttttc atttcagcta tcgtcggcaa
    17641 tagatagaaa gtcaactgtc cttcaccttt tagtgtgaag ttgccagata ccagttgatc
    17701 attgttttga gtcaaatacg atgcttgtgg aatctctgag agatcagttg tcagccaata
    17761 agcgattggc tgtcccgtct cttcagatgt atctgctaag atatcgatca aacgtaaagc
    17821 ggctactcgt ccagtagcag atcctgtgat tgtcaaccat aaaagttccc gttttgtatc
    17881 atatactaag ccccctacat gtggccgttt aggtaaaatc agcagtttga tcggctgtcc
    17941 tgtttctcta tccagtacat gaataataga atgatgctga tggtcatagc agtaggcaga
    18001 aataaacaca aaatcttgag aaaaagccaa cccttgcggc gtcatccatt gacaaacctc
    18061 attttcgccg gtttccggca ccaccattct tgtttctgtt aatccaggaa tgttatattg
    18121 ttttgcttca gccttttccc aagctgcttg aacaatagga taccgtttta actttttttc
    18181 aatatcctga tgtatccgtt gctgcttcca atgcttaaac tttaggacat agtaaacaag
    18241 aaggccaatg accagcaaca ctaaaatcat tattgctacc cgctgtgtca tttttttgcc
    18301 tccttgttct attcgatcaa tcgtccatat accgctatta attaccgtaa ctacatgttt
    18361 cttttactag cgtttcttta taggatcttt cataatctca tttatagtaa cattaagaat
    18421 cccttattct actatagtca cttccacatc aatattgcct cttgttgctt tagagtatgg
    18481 gcaaaatgcg tgggcttctt ctgcgatttt ctctgcttgg tccttctcaa gtcctggcaa
    18541 agaaacttct aaaacgaccc cgatttggta gcccccatct tctaattgaa ataaagatac
    18601 ccgtgctttg acttcagaat cagactcaag attattttct tccagcatgt gttgaaccgc
    18661 gccgttgaag caagatgcgt atccagccgc aaaaagttgt tccggatttg tcccttcact
    18721 atggattcct gggcggtcga tcttcatgtg catacttccg tttggtgcct caacttcgcc
    18781 atcacggcct ccacgattga tcattgctgt ttcgtacatt tttttcattg agatcatcct
    18841 ttctttcgtc gttctatatt aagtgtaacg agtatttttt aatctgacaa aggtaatgct
    18901 tgcattcggc gacatcagtt agacaacatc gatgatcagt gatagaagca gtttatctat
    18961 acaaaaaaag aagggttcta tgatatttgg tgtccttact cgccttgagt aacaacacca
    19021 aatatcatag aaccacttaa tcagcttcac actgcttttt ctactttcgt agttgaaaaa
    19081 aacttaaaca aatcatcggc aaatagttaa agaaaaaact taatcgttga aagaagccca
    19141 attgcttaaa gaaggcaaac tgactaatcg acggaatccg tgctaatccg taaagacctg
    19201 caattagtaa actaataact gttaaaacaa gataaaaatg gctaagcgta ccttgaccac
    19261 tttgacgata aagcagaaca agtaacaatg ggaaaagtag aaagcctgca tagcctagcc
    19321 cagaacctat attatggatc caagtcgata gattacaaga gctttcattc gtattgatac
    19381 tgaataagcc agtaaaaata caatcaccta tcccatataa accaactgtt gcaacaacaa
    19441 gtattgcaag tgtttttgat gttccaacaa ataggtgata caacgcaggc aacgaaagaa
    19501 caaaaaaaag tccagataca actgaccaga ccaagaaagc acgtctgact ggactatcta
    19561 cgtcaccaaa cacactaatt acggtagtca tttgattcag tttgggataa aaaaggccaa
    19621 ggatatacgg tgtcgataaa tcactcatca cacctaataa taaaaaataa aaaccatatt
    19681 tttgcaaaaa aatcattttc ttcccctact ttttagtgat tattcgatac atccaacaat
    19741 caaatttttt ctcattttaa cacatatttt tattctagtt gtcttttgaa caatcaataa
    19801 cataaaggtg agtttcttct acattttaaa aaatcgaatg gcactgaaga gttcagttgt
    19861 cagcatcaat ctcctactca aaaaggcaaa aaaacgtaag tcagatgttg ttgacatctc
    19921 acttacgcat ccattgattg aaaatttctt agtaaaatct actagcctaa aaatttgaag
    19981 acttcttctc gatcatacag tttaaatact ttctcgcata aaaattgagt aattagtgcc
    20041 gcaaaaacag ggatgactaa ccaacaaaga acaacaagaa agccatttag ccctgcatct
    20101 aaagaagcca acggaccaac aagtccgacc acgccgaaac cagcagaagc aggcgtacct
    20161 gaaatagaaa atagagcgac aggaatagct gtaatcactg cactaactaa acaaggaata
    20221 agaatcacag gttttctaaa tagattaggc atcatcatct tcatagcgcc taaagcaatc
    20281 gcaattgtca cacctgactt attaaccttc caagagttca ctactaaaac aaaagtggtt
    20341 gcagctacgc ccatcgcagc cgcaccagca gaaacaccat ctagttggat tgccattccg
    20401 attgctactg ttgaaatagg agagataatc aaaaaggcaa aggaacaacc aatcaagata
    20461 gacattaaca gcggttgtaa ggtagtgaag ttattaatca atgatccaat tgcagaagta
    20521 attgctgtta caaaagggaa taaataaaaa ccaagtaaac ctgcacctac acctacaaca
    20581 atcggtgtta acacaatcga cactgaccca aaactatttc caatcagtaa aatcagcccg
    20641 acagcaatcg atgctgtcag catcgtatta ataatatcgc ctgtaccagc accaacgtaa
    20701 acacccgttt cacccaaatc aggtgtgaat ttgactacac cagaaccaac aaaagaagct
    20761 ccggctacaa ccatcattct catcggatca aatccaaatt gtaaggcaat caaaccacca
    20821 atgatcaaag gtgttgctag ttgaaaaata actgctaact gtgcgatcgt taccgcaaag
    20881 ggatacgcac taaaatattt taaaatggca cctaatactg cattaggaat caatccaata
    20941 atgattcctg ttgctgtacc agcgaggact ttattcagaa aaattttcgg tgatattttt
    21001 tgtgaagttt ccattcaatc tctcctttat tttacgttca aactatcttc ttttgcatgg
    21061 acaagctcag tcaagaaatc acaataaggc gtcgcaacac catatttctt cccttttcta
    21121 gaaattgcgc cattgatata atcgatttct gttaatcgat ggttcttaat caagtcttga
    21181 tacattgaag gataatgtaa cccaattgtt tccgggtcaa aacaagattc acaatgtgca
    21241 atgacttctg ggacatctag ttcaatcttc tctactgctg ctactttggc aaactcattg
    21301 acaatcgtcg ccaccatttt atgagcagtc gatgtttttc ctagctcagc catattaacg
    21361 tctaagattg tgcatagtcc gttcattgtt ccgttcacac atgctttgcg ataaatagaa
    21421 tagtgaatat tgtcagaaaa atgagcattt aatcctgatt cagacaattt gtctgctaat
    21481 ttttttgcag ctgcttcttt tccatcacct aaattttgta attctactga accacttcca
    21541 aataatttga cctgaccagg accttcaaga cctgccgtcc acatggtatt tccaatatag
    21601 atattttcca ttggtacaaa tttctcaata atatcttcat gcccgatacc atttaataga
    21661 cataagacct ctgtatcttt tttgattaat gattggatat cctgcagcat tttttccagc
    21721 tgcatcgctt tggtaaatag aataatcaga tcaacttgat cttctttttc tacttcggat
    21781 tgaagaacga ttggtagttt tgcttctacc tctttaccat taaaatttgc ttgtaatcca
    21841 tgttctttga tttgttggac atgttctgcc cagccatcga ttaataatac ttcgttccca
    21901 ctttggtgaa gcatcaaccc aaagcgactt cccattgcgc cagcgcctgc aattgctatt
    21961 ttcattgatt cttcctcctt tttctttcta ttatactcat ttgagaatct tttcacaacc
    22021 tcgttttgtt attcttctct tatttatcat gtttatatcc accattcaag ttattttatc
    22081 agcaaatcaa taaaaactgg aatagaatcc caatttcatc gtaagagaaa ctagactagc
    22141 aataagaaaa tagaaacatt catagaaaaa atctcactcc tctgattata aaagaggggg
    22201 cattaacctc gtgtatacta aaaccttcca ttcattcgat ggatgatttt ctttttgtga
    22261 aaaaatattc attgtagtac gatgttgcgc aacacagacg gatggtattg cttattattt
    22321 attaaaatcg aacaatacac ttatttaaaa acttctttcc cagattttct tccattttta
    22381 cagttataac tagtattatc atgaaaaata gccttttatt gtctatggga ataataattt
    22441 aaaattggta cttttttatt aattagttca tcgcccaata atctctccag tttcttagca
    22501 tctcctgact caaccggaat tatccaagcc cagtctaaat aattttttaa aatctcatca
    22561 tattttgcaa atatttcatt gccatattcc gtccttaaaa ttatattttc agtgccagac
    22621 aagtgattta tattgagttg ataaaaaaga tctccatcta aaaaaatatc attagaagaa
    22681 gatttcccca cagtaatgac cattccatca gctctatgtg ttacatacaa ataattgtat
    22741 gacctcattt cacctaatga atcaattatt tcttgccctt tagctctaat atattgatct
    22801 ctattaccta tctcactctt atttaacaaa agttttttca tgtcaaattt aatcggctgt
    22861 tttatttttg taaattcgct tctactacta atccaatccg agattaattt ttcaacatgt
    22921 cccagagtaa actctgattt attcgctaaa tacttttttt gttgtattaa agacatcttt
    22981 ccccgaagct caaaattgag cctacatcga ttctctatct cttcaaaaag catcttatct
    23041 tcatcattct tatattcatc attcataaaa ccaatccagc tcctcgatta agataatatt
    23101 ttaatctcat acaaaaacta gctctcatca aaacaaccat tgttttgatt tctcatgaaa
    23161 tttctttata cttttctccg attataaatt cctaacccct tgagaaaatt acgcatatat
    23221 ttatctccgc aaggcttaaa atttcgttgg ccttcttttc tcaaaaatgc cccgatttcg
    23281 ccttttgatg gatagatttc tgcctcagca aaaacgtcta aaatatcatc agtggtcata
    23341 gacaaggcga tttttaattt ttttagcaac acattgttga tatatttgat ttccttgctt
    23401 ttttgcggcg tgtctactat cggcttatct ttttgcggac cacgcgccaa gagaatcagg
    23461 ccatttagga atgcgtcaaa aacttggttg ttgatggttt tttcatacac attattttct
    23521 gcattatctt tgttcttatc ctgtactttg gtcagtaccg cctgagcttc ttctttagtc
    23581 agtggtacac cgcctagctc aaaagcttta atcaaatccg tatctttcaa atcaatcgca
    23641 taacgcaatc gcaataacct atcattgtta ttcatttgtt cctccgaagt atttagtctt
    23701 tactttctta cgtacttttt gtcttgctaa gatttttagg atcaatgata aaaaccgcat
    23761 cacttatgat aaggcgctgg gtatcatgag tgaatgatat tgctgaatac aaatagtccg
    23821 accacattaa gttgatcgga cttcataagc attttattga ctaatacttt tttgcttaag
    23881 aattgattct aacatctttt gctaaagtta agcatcctat agttcctgca ttatctgcta
    23941 acttaggtgt gacaatgtat tcttcgatat ttggcgtatc gacatagccg ttaattagtt
    24001 ctaaaaaacg tctttgtact ttctttttca gatgttcttg ttgcatgaca ccaccaccaa
    24061 aaattataat atctggtgaa agcatcaggg tcgtattaca ggcacattgt gcaatataat
    24121 ccgcctcgat ttcccagaac ggatcttcta tagaaagatc ttgtcccttg gttcccgtac
    24181 gcatctcgat agcgggtcca gatgccaacc cttcgagaca atcatgatga aaaggacaag
    24241 taccagagaa agtatctcct gaatgtctct taactaacgt atgccccatt tctggatggc
    24301 taaacccttc aacaaaaatc ccatcttgta tagctcctcc accaattcca gttccaacag
    24361 tgtaataaac aacactggat aaaccttttc catgacctga aacatactcc ccgtaacaag
    24421 cagcattcac atcggttgtc caggcaattg gaatttcgaa atgcttattc aacgttccaa
    24481 caaaatcaaa atttttccag gcagtttttg gagtagaggt gatatgtcca taggtctttg
    24541 attcacgatg gatatcaatc ggtccaaatg accctactcc aatgctttct aattgttctt
    24601 tatagtgatt aaagaaatca attaccaaac tcattgtttc attcggtgta gttgtaggaa
    24661 aactcactct ttctaaaacc tttaaatcat cattgccaat ggcacaaaca aatttagtcc
    24721 cacctgcttc tattgagcca tacatttctt actccaccgt ccttttatct aggaattcgt
    24781 tcttccctgt ctaatagttt ttcgaaaaac tcatgtggtt ccttttggta ccaataggca
    24841 acagaagaaa tatcgtcttg acgctcataa agcttgatgt catcatttcc tagggtttgg
    24901 aaagtaacac gtaaattttc tttgaaacta atggggtcgg gtaaatgcca gcggtacaac
    24961 ccatgcatcg gtaaagcatc atcgccaaaa ccatgaactg gatttggatt aggttttcca
    25021 gcactaaaat aatcccgggt gtgatctctt ttagattgaa aaggatagcc cataaatagc
    25081 gtattaaaat tttgagcata tgccctttct ccaaagttct ttttatggaa agcccaagcg
    25141 ccgccaaaat aatcttctgc tcctgtagat gttattgtag ggaaatcttc atctccatct
    25201 atataaaact taaattctcc ttccccccac cagtatcttt ccaatgcgca caaagcaaag
    25261 taggttccta cataataccc agtgcctttg attccatcaa taagggtgta atcttttcct
    25321 tttgtcgtga tgggttcacg gttccattta gcatgaaaat acatcgcatc atccggtact
    25381 tcagtcaatg cataattaaa tgtataaaaa atgtgcttaa taaactcagg atgttcattc
    25441 gttaaagtaa tcttagcttt ttttcgaaat ggcatctcaa aatagcaatt catccctgat
    25501 gttggattca ctacgattgg taaggaattc acttcgcatc ttgtcccaaa cccattacaa
    25561 aaaaaatctc ctaatggact ttctacagaa ggagtggatt catcatccca ataaatacgc
    25621 aaaattaaat cacgtaagac gaaactccca gcgattgttt tgtctgtcac tgtcatccaa
    25681 aaatgacgta aaattccagg gccttccatt tctgctaaag taattgtctc tccagcattt
    25741 atcggaacag aaggtgaccc ttttctccca attcctagat gactcgctgt cattgccgct
    25801 ttcccttttt caccattttt attttctggt gaaatagttc tactttcctc tcccttgtgg
    25861 agccatatat tatttaaaca attcatttta ttcgtcctct atcctttctt cacttttttg
    25921 attattcata tagatgattt gttgttgtgc ctccgcaata attgctccaa tatctaaatt
    25981 atcatttcct aactgcaaag cgattgacat tgccaaggga agattcattc ctgcaattac
    26041 gtgcactctg tcagaaatat aggtaaaaaa cttttgattt acacttcctc cagccatgtc
    26101 agttaaaaca attatttcgt ctgtagtatc cactaactct ttaatttgtt catctatatc
    26161 atcaatttct tcgacatatg cacataagct actaatttga ttatgcatac ctgttaaaaa
    26221 ctctagtgtc tctttaaaac cctcagctag tattgaatgg ctagcaatga tcaatcttct
    26281 cataattcaa atccttttcc tttacgctaa tattccaaat gcagccataa ccatcgcaaa
    26341 aacaataacg agtagaatca aaatggtcat actgattttt ttcttactga gtagataata
    26401 tgctgcagca gtaataatta ctggaattaa tgttggtaaa attttgtcca acattggttg
    26461 gattttcata ctaacttcac caaaagtgaa tttaagtggc gttgaaacac tgataactga
    26521 agcaattaat gatccaacta ctgttagccc caatactgaa gcagcttcag ttaaataatt
    26581 aatcttttca ccgtattcag taacaatctt cattccctgc ttataaccaa attcaaagcc
    26641 tctcattcgg aaaaagaaga ttaccatgat taaaatgaac cataaaaaga ttcctacagg
    26701 attattttct aaagccatat aagccgcaat tgatcccatg atggttggga tcatcgtcat
    26761 caaaagagag tccccaatac cagcaattgg acccatcgta ccaactttaa agtcattaat
    26821 cgcatctttt gcttctaatc cttgcttttc ctccattgca acacaagcac ctaaaataat
    26881 ggctgccagc caaggctgtg tattgtaata ctgaaagtga ttatttaaag cttcgatgta
    26941 ttcatcatca tctttgtata attttcttaa aataggtgac aatgcgtaag tcacagatgc
    27001 accttgctgt gtttgataat taaaggtaca aactgacatc aaccaacgat agttcgcttt
    27061 cctaagatcc tttttcgtta cttgatattt ttcgctcatt ttattcatcc tccccaataa
    27121 acccaacatc agaagctccc gcagaagcag tgatttgtgc atctttttca gctctatgat
    27181 acacattaaa tgctaaagcg aatcctatga tcgccgctcc aataataggt accttcaaaa
    27241 aagcggctaa gaaaaatcca acaagtaaat aactaatgta tcgacctgta ggcataaagc
    27301 gtaacaacat cgcaatacca acagcaggca acatttttcc ggctaatgtt agcccatcca
    27361 taaaccaatt aggtaaaaca tccaaaacgt aattaacagc agactgtcct aaagtaacgg
    27421 caataaatac tggaattgct gcagataaac caaagaaaat tggccccaac cacaaaacac
    27481 tattcatttt cttaaattct cgtttattcg catattcctg tgatttgcga acaacaaaac
    27541 catttaagat tttgacaatt acatctagtt gcacccctaa catacctaca ggtagtccta
    27601 ttgctaatcc ggcttctact ccaagctggc taccaaatgc cgttgcaata attgcgcacg
    27661 ttccatagtc cggtacagat gagccaccaa aaccggcaac tcctaatgac atcaattgaa
    27721 ctgtaccgcc aactatcaaa cctgttttta tatcacccat caaaattcct gtgaataatc
    27781 cccaaaaaac tgcgtaattt acaaagatca tcggaatccc ataataatca acatgtttaa
    27841 taaatgctaa tatagtcagc ataataattt gaaaaatagt aaaatgcatt atccttactc
    27901 ctttatccta attttgattg aatttcctgt gccttatccg ccggaacaaa ttgtgtaaca
    27961 atttctacac cagaatccaa caatttttta tacgtgctga tattttcatc tgatgcatag
    28021 gctctagaag atagctgtaa tgcattatct ttaacaacag taccgccaac aattagtcgg
    28081 tcaattctaa taccgttatc tactaaatga aggattgttt ccggctcttt cacgatgaca
    28141 aatacttttt cctgatcgta tttccccttt ttaaaattcg caatcgctgt ttcttcagtg
    28201 ataattgata cagccattcc agcaggtcta gctaaacgca tacttgattt ttggatgtcg
    28261 ttatttgcga cagaatcatc gatcaccatc actctgtttg ctttagacat tggtgcccat
    28321 tgcgtgacaa taatcccatg caataaacgg ttatcaactc tcgacataac aatactcata
    28381 aatacttcct cctttatctt tcattttctt acaagcaatt accatgccaa aacaaaaaga
    28441 acttgataaa tcaagctctt tttacataat cataaacgta tttaacctca tgaatcggga
    28501 tgtcgacact ataataatgt tcaacgacac tgaaagattg cttaaaatgt gtctgaaatt
    28561 tttgaaattc ctcactcgtt tcattgaaat aaatttcatc ttccaaagta ttttgtttta
    28621 ctaatcgttc aattaagcaa ctaatgtgaa catataatcc gaaacacgta ttattatcaa
    28681 atgaaattcc tagatcattt tgtaagatgt atatagcatc tgaaacccgt tctaataatt
    28741 tagtcggatt taatatggtc aattgctcca ttaaattcgt tagactaaaa ttcttcagaa
    28801 tattattgtt caaaactttc agttcattat cattaaagtg tctattcaat tgattggaga
    28861 atttacttat attcattcct aaaatcatat cttcaattga aaagaattct acatcttcta
    28921 gatgtggatt tagtgttcca acaataaaaa gaatattgtt ctctttacga agctccgata
    28981 aatagttttc attcactaaa gagtaatagt cacacgtttc tatgacaaga tcagtatccc
    29041 ttggaaagct atcttcaagt atccttttta atttaaacga agttcctaat ccgcttgcac
    29101 aagaacagac aatcatatcc ttcttaatat ttgatgattc ataaatataa tccacatttt
    29161 gattttcttt tacttgttca agaatctgtt taagcggtaa atctaataat atctgatttg
    29221 caacatcaat agccattctt gttgaaacat tgtttagtag tccgaatttt ttttgagcgt
    29281 ctagttccaa atttagataa attttctcca gtgaacccat atcaacaagt aaaataattt
    29341 cttcatatcc ggtacactct tgtaagtatc tattaatttt gtctgcaatc tcactacttg
    29401 aagtcattag tggcatatca atggcgtcgt atatatatct ctcaacgatc ctattagcag
    29461 tacttgctat acaggttgcc gttagatctc catgagccaa aatcagtgct aaacgttttt
    29521 gctgaaattc tttactacac attaacttaa ataaaataac caaaacattt ttttgaattt
    29581 ttgttaaata aatatcccct atttgaataa aacgattgac taattgaact tctcgactac
    29641 accaactatt aatatcattg atgaaggaat ataatttatc gtccgatgtt aattggattt
    29701 gataaatcca agaattcaaa aagatagacg ttatttgaag ataataatag tcaaattcta
    29761 tttgaaaatc tctctctatt tccttaacat actgtctaaa tcgaatctct tgataggtgg
    29821 gatatgttaa agctgaatta ttttggatat caacattctt ttgtctaaaa tatctatcat
    29881 atttctcaaa aagctgctgc ttatcagtgt ctttcttcca cgtttgataa agatactcta
    29941 taagttcgtt gatattaaaa acttcgtcta ctttttccaa atcatccatt tgaatatatt
    30001 ttaattcatt ctgtcttttc ataaccttca tgccgttgaa attcacccat tgtggtaaat
    30061 gatacatctg aatataaagt tcttccaaat catctaagaa ataaaaggca ttggcacagg
    30121 tcaattgaat gatatttttc aaattgccaa cattttcact aaagcgatag tttaataaaa
    30181 aatctaataa ttgttgagat atcagtattt tctttgctag tctttcttct tctgatttaa
    30241 aaaatatctt gattaactgt tttctttcat aaagagaacg actgtctaat gttggaagtg
    30301 ttagctttac aggtattctt ctcaacaaag ttgataatag tttatcctca ggtggttctg
    30361 atgttgcaaa tataatccag caacttgatg tgtaccagtt ttcattatca cccatccgat
    30421 gaaatttcct cgtatccata aactgaaaaa gtttctcctg acattcattg ctcaatgcat
    30481 gaatttcatc taaaaataag actccattat tagctaattc tgctaaaccc tttcttccat
    30541 cttcggctcc tgtatatgca ccttttacat gcccaaaaaa attggacaag aaaagttctg
    30601 gattattggc atattcacta caattaactg aaatgaaaga tgccttctct tctatataat
    30661 tattggccaa caaatcctta tacacataat ttgctaaata gctttttcca gttccagtct
    30721 cgccatgaag taaaatgggt aagccatttg gcggatagta gattgctgct ttaatttgag
    30781 caattacatt tcgcagactt ccttgacttc cgataaccct ttctattcca accctaaaag
    30841 agctatcata ccatttttcc gcttcctctg aagagctaaa aatttgttga tttggaactt
    30901 tctccggtaa agaaaagaag attactggac gagtattgat ttttccaaat tctccatctt
    30961 ttacgaattc attcaaatat tgagagacaa tattacgact aacatttaat ttttcagata
    31021 ttttctgtgc tgtattgttc ccccatttat ttttaatctc agagttctct atgacataat
    31081 tgacaatgcg ttcttttaat tcttccatca cagcacctcc tcgacactat tcgaattttg
    31141 ccgacagtat ttttccataa atatgacttg ctaaaaaggc tttgtttaga tcattcaatt
    31201 ggaacgttgc ttgttttgct tgatccgcta agacgttgaa aagatactct ggcgaaatcg
    31261 cataccccaa aatatcaacg attgttgcaa tcagatcttc ttttgattct tcatctgaaa
    31321 gtaattcacg atacaacatc gtttgtttgc ttactgtgtc atattcctct aaggattcat
    31381 ctgctaaaag aaccacttgt tccaacaaac ggtcggataa atatttatag aaaatcagcc
    31441 ccaataaata atttttatat tctgacgcat ccattttact acggagatta tctgccgcac
    31501 taaataactt ctgatttaat tctgcaccca aaaagataca ctcctatctc ttatttaaag
    31561 ttgctatata ccctcttatt ttagcatact cagttttaga aaaagcaaaa aaataaagaa
    31621 acttattctt gataacaagc tacgtgacgt atatccctaa cacaaaaata gccatatcct
    31681 ttggtttgga tacggctatt tgatattact cattcaatta tcaaatcaca gtaggtgtga
    31741 atctcatcgg gatcggcaat atctacttct gattaggatc aaaggtgatt ttctcaataa
    31801 aggtgtgata caaagcttta acttgcttct tctcactctg gataagaaag caatccaaac
    31861 tagtcaatat ctgttggaca tctttgactt gaatcggttc cccttgttgt tgaaagatcc
    31921 ctaagatttc attctctcga atttgtaact gtcttcgttt ttcagtcaat tcatttaaac
    31981 gatcttttaa catcggaaac aattcgggac tatcttccaa agcagcttcc tgtttttgct
    32041 ctaatagtta gattttgcgt accattttct tcttttattt tccttcgatt gctgatttta
    32101 atatagtcta aaggaaattt atatttattg tattctttat aacttcaaga gaacttcgtt
    32161 tgagtattac tgtatttttt taattccata agaaaattag ttattacctg ccacctaatc
    32221 agcaaatctg aacctgagtc aatataatta atattatttt ccatctccaa cattgtaagt
    32281 actgttggtg ttaatatagg gactttgtac aattgtattt ttttgatttt atcatctgca
    32341 caaaggagat tttttaaatc taatccttct tttatttcaa aagttgaatt ttttaaatct
    32401 ataagagtaa aaccaattcc ttcatactga atttctgaaa atcgaatttt tctcccagtt
    32461 gatagatcaa ggggcagaaa accttttatt acattgtgag tgtcaccatc atttacaatg
    32521 tcattaggaa ttttgatttt agaattctgt ggagcaccta ttggaagata ataattcatt
    32581 ataattttgt agtcttcatg aggaaataaa gtacttttag gattgctaag atattctcgt
    32641 accgaatcta agaatggctt atccattgaa tcttcatccc catttaaact aaaaaacatt
    32701 cctacaattg cttttgcaac tctaagtgaa ttcattttct ttattgaatg tgttaaatca
    32761 gacttaccat tctttaaact tgtattgtta taaaggaaat ttttattgtc ttctgcaaat
    32821 ctaatatatt cctcaacata ctcactacca aaaaaactat tacatttact acataacgt
//
LOCUS       DADQCX010000024        31522 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.024, whole genome shotgun sequence.
ACCESSION   DADQCX010000024 DADQCX010000000
VERSION     DADQCX010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.024"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(111..578)
                     /locus_tag="J8R83_001062"
     CDS             complement(111..578)
                     /locus_tag="J8R83_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAZ9574203.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(698..2236)
                     /locus_tag="J8R83_001063"
     CDS             complement(698..2236)
                     /locus_tag="J8R83_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAZ9574204.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            2316..3002
                     /locus_tag="J8R83_001064"
     CDS             2316..3002
                     /locus_tag="J8R83_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAZ9574205.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(3203..3730)
                     /gene="msrA"
                     /locus_tag="J8R83_001065"
     CDS             complement(3203..3730)
                     /gene="msrA"
                     /locus_tag="J8R83_001065"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9574206.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(3814..4491)
                     /gene="pgmB"
                     /locus_tag="J8R83_001066"
     CDS             complement(3814..4491)
                     /gene="pgmB"
                     /locus_tag="J8R83_001066"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAZ9574207.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(4488..5618)
                     /locus_tag="J8R83_001067"
     CDS             complement(4488..5618)
                     /locus_tag="J8R83_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAZ9574208.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(5618..7801)
                     /locus_tag="J8R83_001068"
     CDS             complement(5618..7801)
                     /locus_tag="J8R83_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAZ9574209.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(7798..8823)
                     /locus_tag="J8R83_001069"
     CDS             complement(7798..8823)
                     /locus_tag="J8R83_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9574210.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(8868..9695)
                     /locus_tag="J8R83_001070"
     CDS             complement(8868..9695)
                     /locus_tag="J8R83_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9574211.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(9692..10759)
                     /locus_tag="J8R83_001071"
     CDS             complement(9692..10759)
                     /locus_tag="J8R83_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAZ9574212.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(10785..11621)
                     /locus_tag="J8R83_001072"
     CDS             complement(10785..11621)
                     /locus_tag="J8R83_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574213.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(11618..12487)
                     /locus_tag="J8R83_001073"
     CDS             complement(11618..12487)
                     /locus_tag="J8R83_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574214.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(12557..13840)
                     /locus_tag="J8R83_001074"
     CDS             complement(12557..13840)
                     /locus_tag="J8R83_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574215.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSENGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(13854..15539)
                     /locus_tag="J8R83_001075"
     CDS             complement(13854..15539)
                     /locus_tag="J8R83_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAZ9574216.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            15814..16839
                     /locus_tag="J8R83_001076"
     CDS             15814..16839
                     /locus_tag="J8R83_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9574217.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(17434..21087)
                     /gene="rpoC"
                     /locus_tag="J8R83_001077"
     CDS             complement(17434..21087)
                     /gene="rpoC"
                     /locus_tag="J8R83_001077"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAZ9574218.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(21166..24783)
                     /gene="rpoB"
                     /locus_tag="J8R83_001078"
     CDS             complement(21166..24783)
                     /gene="rpoB"
                     /locus_tag="J8R83_001078"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAZ9574219.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            25511..26479
                     /locus_tag="J8R83_001079"
     CDS             25511..26479
                     /locus_tag="J8R83_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574220.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            26497..27402
                     /locus_tag="J8R83_001080"
     CDS             26497..27402
                     /locus_tag="J8R83_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574221.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            27399..28205
                     /locus_tag="J8R83_001081"
     CDS             27399..28205
                     /locus_tag="J8R83_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9574222.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            28362..29330
                     /locus_tag="J8R83_001082"
     CDS             28362..29330
                     /locus_tag="J8R83_001082"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAZ9574223.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(29647..30171)
                     /locus_tag="J8R83_001083"
     CDS             complement(29647..30171)
                     /locus_tag="J8R83_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAZ9574224.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            30458..>31522
                     /gene="scm"
                     /locus_tag="J8R83_001084"
     CDS             30458..>31522
                     /gene="scm"
                     /locus_tag="J8R83_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAZ9574225.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         8847 a         6802 c         5937 g         9936 t
ORIGIN      
        1 gctcaaaaaa cggcaaaata tgaggaacta ttttgacgtt tgtttctcta atactcaggt
       61 caaaacgctg atttcacaac ctctttttcg gtcaagttca acaacagttt ttacgcgtcg
      121 atctctggcg ctttgcccaa atgagcttgg atcatccaga tacgtttttc tgtggctgtt
      181 ttgaattcga taaagatatc ttgtgttgga tcgtcgcctt cttctccaga aacttcgatt
      241 cctttttggt aaagatctgc tagataacga tagcctgcaa caagtgtttc caaacgttct
      301 ggaatagtac gatcccagcg gccaatttca tcagggattt ttgtgttatc tgcaaattca
      361 cgcaatgtag aataaggtga accgtctaat gtgatcaagc gttcggatac ttcatctaac
      421 tgagcgttca aatcatccat gaactcatcc atcattgggt gcaatgtaag gaaacctggt
      481 cctctcatgt accaatgtgt ttggtgaaca acaacagaca tttggcttag atctgcaact
      541 aattgattta atacttcttt ggtttgttgg aatttcatct ttcttgcctc ctaacatttt
      601 cttacactta aaataatagt agactttcaa tgaaaagtac aacaaaatca tttacctgag
      661 aacgattttc agttcgcttt tttatccgta aagccaatca tttttcagaa tcagctaatt
      721 cttctcgcag ttgagcaaat tgctgataag tctgtgctaa atgcttttgt gtcgaaacaa
      781 ataatggata gattttctga tattttttat gatcagtttc ttgtactcca acttgctctt
      841 tcaattctat caattcctgt gcttcactga tactttggat ctttccgatg cttctccagc
      901 ctaaaatcac agctcctaat gcggatgctt ctgtgacagt agggaaaaca agcgggtaac
      961 ccagtacatc agccatcatc tgacgaaaaa tcggagattg agcaaacccg cctgtagcac
     1021 ggatctctgt gagctgattt tcctggcaaa ctccttttaa aatccgataa aggttgagac
     1081 agatcccttc tagaatcgcc ttcatcattt ctttttctgt atgttgccgc tgtaaaccga
     1141 taaaactgcc aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt aaatagggat
     1201 gaaaaatcag accattggca cccgctggca caaaagcgat agccgaaagc agtgcatcat
     1261 atggattttc tcctttttct ttagcagatt gaacgacttc ctgtaaaaat gtatgccctg
     1321 cccaatcaaa gatgccagca ccattgctag tcgctcctcc cactacccaa tgtttctgat
     1381 ccagaacata acaaaacgtc tccatttctg gatggaactg aggctgagta gtaataaaac
     1441 gaagtgctcc gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa gcacctaacc
     1501 ctagattaga aagcggcccg tctgcccctc ccaaaacaaa tgatatatca tttggcaaac
     1561 ctagttctgc tgctgttttt gatggtagac ctgttacttg ataggtggaa ggaaagactt
     1621 gcggcaattg ctctattcga atgttcaagt agtcaagcac ttcttctgcc cattggaatt
     1681 catggatatc aaaatatcca gttcctgaag ctgttccgta gtcgctgatc agttcgccaa
     1741 acaatctata aaagatatag tctttgatac cgacaaaata agcagttttt ttgaataatt
     1801 caggttggct gttttgcagc cacttgattt tgttcaatgg tgtcattgga tgaatcggcg
     1861 tcccagtctg ccgataaaat tctttgccaa gcacggtata tttcagtttt tctgcttcgt
     1921 ccgctgctcg gttatctgcc caagtgatca ttcgagataa cggtgttttc tcttcatcca
     1981 acaatatcag gccatgcatc gcagaggaga aggagacaaa ttgaatgatt gtgtctgaag
     2041 gcaactgttt aattacttct tttataacgg tgcagacacc ttgaaagatc aattcctgat
     2101 cttgttctgc catcccttgt gtttcttgga tcaaagggta gcgaaaataa gcggatgctg
     2161 cttcttgggc ttcatctgtg aaagcaactg ctttggtttg tgtggttccg atatctaatc
     2221 cgattgaaac gttcattttt tcacctcaaa ttttatgtat gtacaaaaat ttagtttaag
     2281 cttgcgtatc ttggttttga aaagggggag atggcgtgtt actttatttt atcattggtt
     2341 gctgtatcgg atcattttta tgtttaaccg cccagcggat tccgttaggt cactctatta
     2401 tttatcctag atctcattgt gtcaaatgct gtcgttcgct ttcttggtat gaattgattc
     2461 cgattctctc gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt cggttgccct
     2521 tctactattt gttggcagaa gccttatgtg gtggtctttt tgcctggttc tttacttttt
     2581 cttccgcaag aaatttttcg acgttcatat ggatgctttc ggctttgcta ttttcgttga
     2641 tggatttatt ttacttcatg gtccattctc acacgctatt ctgttcttgg gcaattttat
     2701 ggattttttg gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta acgtttatcg
     2761 taggcggtgt gtgccttcgc tatggtcaat cctatctcgg agctggcgat actctgttga
     2821 tgctttcttg gagtggtggc ttgtctctag aagagttgct tcagatcttg tttcttgcta
     2881 gtctgtttgg aatatccgtt ttttctgttt actttatctg tcataaaaaa aagttggaaa
     2941 agctgccttt cattcctttt ttgagcagtg cgttgctgat tgtccttcat cttaggtatt
     3001 gaaaaaaggt tgtgacaaac gacttgtcac aacctctgat atatagtgtt ctcttaccaa
     3061 atccttgtga cttggagcta ggcgacaggt tcacaacctc tccactaaat ggtgttcaat
     3121 cagctgaccc tcagtattag ctcaaaatgc tggttttaca acctctgata tacggtgttc
     3181 cataagtagc tttttcggct tcttatttct tgacgcccca atgtcgacga aggaaacctg
     3241 cacgtccaga accttctcga taaagattgt aatggagctt gtttttcttg taataatcct
     3301 gatggtaatc ttctgcagga taaaattcgc ttcttggttc gatttttgtc acgattggct
     3361 tatcgaatcg cccgctgtct tgcaatgctt gttttgaacg ctctgcaata tttcgttctt
     3421 cttcatcatt atagtagatc actggacgat aagaatcacc gcgatcagcg aactgtccta
     3481 atgcgtcagt cggatcggtt tgctgccaat agatttccac caactgatca taagaaataa
     3541 cttctggatc atattcgatc tctactgctt ctgtatgccc tgttgtgcct gttgttactt
     3601 gttcataagt tggatttggt acatgcccgc cagtataacc ggatgtcaca gaaatgatcc
     3661 ctggctgctc ttcaaatggt ttgaccatac accaaaagca tccgcctgcg aaaactgctt
     3721 tttttgtcat ataaaatccc ccttttttct catcatacct tgatttccaa aaggaggata
     3781 acgttttgct tgtgacagaa aaaacggaaa ctattatata cgtgatacgg cttctgataa
     3841 atgccaaaac gaacgtactt gatcaaaaac ggttaaatca ggaatcacat attcagcaga
     3901 aggaagattt atgttttcac ctattcccaa tacatgcatg ttaccagcca aagctgcttg
     3961 acaaccagct tctgaatctt caatgaccaa gcatgcattt ggcggtacat tcaattgctg
     4021 tgctcctttg agaaaaactt ctggatcagg ttttgctttt gatacttgcg tgccgtcaat
     4081 aaggacatca aaataacttg tcaaattcgt tttttctaaa atgaggcgtg catttttgct
     4141 tgctgatccc aatccgatct tgatgtttgt ttttttcaag tactcaagaa cagctattgc
     4201 accaggcaaa acggatgttt catccatttt ttgaatcgct tgaagatata gattgttttt
     4261 ttgctcagca aaggctgatt tctctttttc tgagaatttc tgttccattt ttccaaatga
     4321 cagcaatcgc tctagtgact cggttctgga tattcctttc agttgctcgt tttctttctc
     4381 agtgaatgga atggacagct ggttagctaa aaccagccac gcttcgtaat gataacgagc
     4441 tgtgtctaca agaacgccat ctaaatcgaa tagtgctgct ttgattttca tcgattacct
     4501 ccttgaaaat gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg atgaagatta
     4561 tcagtggctt gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat cggaaaaacg
     4621 gccgaaatgc caacatctgc tgctttttcg cttcctttac caacacttcc gcaaatagct
     4681 atcacaggaa cgccctctgg tactcttcta gcaatcccaa ctggcgcttt tccttttaga
     4741 ctttgtccat ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg tacccgttta
     4801 tcgaactcca gtaaatccaa tacgtagtcg atgccagaga ctattttccc tgaagcaaat
     4861 gctaacagtc ctgcacccat tccaccacca gcactactgc ccgatgcctc gattacttga
     4921 ggggcaaatc tcatataaaa atcatgcatg gcttggtcag ccactgctaa ttcattttct
     4981 ttcaagcctt tttgtggtcc gaaaacaaaa gaagcgcctt cttttccgca taaaagatta
     5041 gtaacatcag taatgacagt gattttggct ttaatcagct caataggcac gttcgtttta
     5101 tcaactgtag caattttacc tagattttct cccagtgctt ctactttttg attatcttga
     5161 tcgtaaaaag cataacctag accttctgcc atgccgatgc cgccatcgtt ggtactactt
     5221 ccgccaacgc cgatgatgat gtgtcgaaca ccttgttgca acaattgtcg tatcagttct
     5281 cctactcctc gcgtggataa cctaagtggc tgttgttggt ttagtgggac atctttcaat
     5341 ccgacgattt ctgccatttc aaaaatcgca gtttgaccgt ctgaagcgta ctggatttct
     5401 ttgtttttgc caaatgcatt agtaacgact gctgtttgcc gcttcaacct taaactgtct
     5461 gctaatgatg aaaccgttcc ttctcctcca tcgcctatag gtagcagatc atattcagcc
     5521 tgaacaaaaa cttcttgaaa acctgattga atggcttgtg ctgcctctaa ggctgtcaga
     5581 ctttctttga aagaatctgg cgcaatcaga atacgcatta ttttcccctc cgttccaaga
     5641 tcagttcttt ttccagctgg tattggtctc cattgacaaa aataggtaat gtttctttcg
     5701 tctctttttt tattactatt tgtttttttg tcaaaacaaa tagcaacctg tgatttttcc
     5761 aaataaaagg aaaagaaatt ttttcccatg ctgaaggaag tcttggagaa atagaaagag
     5821 ttccattcgt tactgtaata cctgaaaaac caaatataac tgctagccat agtgctccta
     5881 atgaagcagc atgaattccg tcatctgatg aatgcggatc tggtcctaaa tcaatcaggc
     5941 acgcttcttg gaataaatga tacgcccatt ccatttcttg gatacggcaa gcctctatgg
     6001 cgtgaatcgc tttactcaac gatgagtcgt ggattgtttt gttttcatag taatgcaaat
     6061 tcttagaaac gattggttga gaaaaatact caggtaataa gtataacagc atgacaagat
     6121 ctgcttgctt gctgacttgg agttcattta cttcgctacg ggcataatca agtaaaatag
     6181 actggctgcc aggacgttct ttgtaagtgg tcaaatcaat aactggctta ctgagatacg
     6241 tgtcatcttg cggaatcagc tgttctttgt taggcactgg caaatataac ttatctaaaa
     6301 aattttgaca ttctttcaaa aaaagcggat cgccagcttg atatttaaca gctaaggcca
     6361 cattataatg cgccagatag ttcgtatatg cattattgtc gatatattct gtgtattcat
     6421 ctggaccaat gactctgtgt atctctaaat gatcatcgac ttttacagct ctgctcagcc
     6481 aaaaagctgc tgtttcatga atgagcgttt ttccctttgt ttctaaaaac gattgatcct
     6541 ctgttgcttg gacatactct tgaacggcat aagcaaggtc tgcactgata tgatgttctg
     6601 cggcagctga agcaacttct tgtcttgttc cggttttgat attcaatgca gcaaatttgg
     6661 gtgtctcttc ctgaccagtg tgtgcgcttt cccatgggaa aagtgcacct tgatagtgat
     6721 aatctcttgc tttttgccgt gcgccttcta atcgatcata acggtacagc agcaaattct
     6781 ttgctacttc aggaaactga tataaaaaga aaggcaggat aaaaatttcc gtatcccaga
     6841 aaacatgccc tttataacct tcgccagtta gtcccttcgc ccctacacta acacttggat
     6901 cattgcgggg agtcataatc tgtaaatggt aagcagcgaa gtccatcgct aactgatcga
     6961 aagaagaatc gccttggatc gttatccgat gctgatgcca aaaatctgtc caataagaca
     7021 tcgactgctc taaaatttct gtataactaa cgcttttctg ggcttgggca atacttttct
     7081 taaacgggtc tgtttgctga agagaggtag agagcacgat gatcttctcc agcgtaaagg
     7141 acgtattttt tctgatcttt tctgaaaagg aagcggtgat ccggcgattt tttgcttgga
     7201 atacacctgc tttattgaat ttagctgcaa tcccaatatc aattttactt tctgttgtct
     7261 ggtaggatgc actgatcaaa tcgtcaccaa atactcgcag ttctttttca accaactgct
     7321 gtgtaccaaa attggtttgc tgtccatcga tacccgtttt cacatctact tggcagtctt
     7381 cggtcaacgg cttgatgacc actttcaggg ctgcctgatg gagattattt tgatcagcaa
     7441 cacgacaagt aatgacttcc actttttttc cttgagcagt ttcaatgagc gcatagcgtt
     7501 taagctctcc catttctaaa tctagtgccc gctcgtatgc aagaactttc atcgtctcaa
     7561 gagaaaaatg ttcaccgtcg atttttattt cccatctgat gacatctggg agattcacta
     7621 actcggctga ttctgctcct aaaggtcggt tatatacacc agctgcaaac attcccctta
     7681 cttgattccg atagtcttcc tcctggcttc ctctgatacc aaaaaatcca tttccaatgg
     7741 tcatctgact cgcatactta ttgatatact ctaaatcaaa ctgtttttct tctactttca
     7801 taaggtaata acttctcctg tttctgccga acgatataaa ttttccacca gattctggat
     7861 gacatatcct tgccagccat ctgcaatcat ctgagtctgg tcaccgagcg cccgattcac
     7921 aaaatgagcc atacttagtt catgtgggtc attaactggc gtggtctttt gtaaggaaac
     7981 cagctttcca tctacatctt cgaatagttc gcctggatac agattagcac ctgcctgatc
     8041 gccacaaaaa gccacattca gtttgtcttc tctgatattc aaagcaaacg aagtattcag
     8101 ttggatgatc ttgccgtttt ctaattccag tgtgccaaaa attgcatctt ctactgtgaa
     8161 tttgcttgga tcccatttcc cgaatttccc tgaatttttt ttcgtaccaa ttttttggaa
     8221 gctgtacgcc cgaacgcttt ttactttagg aaatccagta atatacatcg ctgtatcaag
     8281 catgtgaatg ccataatcga tcaaaggccc gcctccttga agttctttgt cgataaacgt
     8341 tccccagcct ggaacaccag accgacgaag cgcattcgct tctacgtaat aaatatcccc
     8401 gagaacatca agatgattct tgatcattgt tgcttcgtca gaaaaacgat gctggaatcc
     8461 ataagccaaa atctgcccgt ttttatcggc tgtctctgcc atctttcttg cttgatcagc
     8521 tgtcatagct ggtggtttct cgcacatcac tgaagcatta gcttcgaggg cagccaatac
     8581 atgttcgaag tgaaagcgat tgggtgtaca gacactcacg atatcgggag aaatctcatt
     8641 cagcatttgt gtaactgatg tatacgcatg agaaaatcct gtacgtcggc aaaagtcttc
     8701 tgctcgctgg ctgactggat caaccacagc ggccaattct aagacatctg atcttttttg
     8761 ataataagca gcatgtactt tttctgctac ttgtccagcg cctatgattg ctactttctt
     8821 catttatttc tccctccttt gcttatttac ttattgttat tctttctcta ttctttctct
     8881 aaatcattta aatgacgcgc tgtttccaga cagtttttca agtattgcaa tgattcctga
     8941 taaattttca cttcattttc tcctcgcaaa cgacattcat ataccatata accttcatac
     9001 tcattttgaa gtagcgtttg aaaatggcga gtaaaatcaa ttgcgccaga tcctggttgg
     9061 tagcgatgat tatctgctaa atggatatga cccacatact ctttttgcgt agtcaatgct
     9121 tttgaaatat catcttcttc aatattcata tgataaaaat cagcgatgat ctgcacatgt
     9181 ttcaattgat tagagtcaat gtaatgacgc gcatccgcta acaaattgat catatggtct
     9241 tggtatcggt tcaaaggctc caaataaata accgtacctg tttcttcggc tactttatct
     9301 aaataacgaa gtgattcgct gactgcttta tagtctcctt ctttgcttcg gggtgaaacc
     9361 atcggcggta atcgataagt gaacattccc caagctgctg ggataacgat tcctttgcct
     9421 ccaacctcgc ttagtgcacg caaaatctca gcaatttgac gtacaccatt aagacgccgt
     9481 tcttcgataa agtcaccgat ccacccatcg tagccgttac aagctgtcac tactgggatc
     9541 cctgtttctt tgattgcctg tttgactgtg tcgatatttt ctattaacaa cttaccgtcg
     9601 atttcgtatt cttcaaatcc acagtctttg ataaatctaa atttttctaa aatgtctctt
     9661 gggaaaaatg cttgatcttg cgtaccgaat ttcattgttc tcctcctcgg acttgaacgc
     9721 ccattttgat actttcttct gggtgctggt ctacataacg catgtaagct tctgcgcttt
     9781 ctgcaaatgg cacaactgga tcaatgattt cttcacaatc caagtaaccg ttcatcaata
     9841 attcccaaca tgtgtcctcg attcgtttac ggttccatct tgggtaatct gggtttggtt
     9901 cactagatgc tcgagcaaag acgatttttg cattattgaa atgtgcttcg cgaccaagat
     9961 taaacccagc tggaaaaggt ttagcaaagg caacataaga aatgatcccg ccatagccga
    10021 tccctcttaa agaagcttgt aatgcggcag cactgccact cgtttcaata actgaatcta
    10081 ctccacgttt atctgtcaat tcctttagac gaaaaccgac atctgctttc ataggatcta
    10141 gcgtgtaatc ggcaccgtat ttttctgcta attctctacg ctgcgctatg ggatcgatcc
    10201 caacgatggt agtagcacct gcttttttag ctaattgaat cgcaatttgc ccgatagcgc
    10261 ctaaaccgaa gattgctaca gcatcacctg ctcgaacatg tgcttcccgg ataccaccta
    10321 aagcgaattg agcaggatcg taacatactg catttttcca ttgatccaac cgatcaagtt
    10381 tacgtagttt ataattatca acaccgtttg taatcagcgt ttcacgaatg ggtccataag
    10441 tgcagactaa ctctcctttt tgatactctg tcaccaaact gcccgtttct tcgatcgtac
    10501 cgacaatcat atttcctaat tgaaattcgc caaataccac accgcgttgg cttccttctt
    10561 ctcttggcaa gaataggcgc cattcttctg aaaattcttc atcgataaat ggacttaatc
    10621 ctctaaagtc gacaatttct gttcctggtt ttggagtagc gaaaattact cggatacgta
    10681 cttcgttctt ttcgatctca cggtcttcgt aatctttgaa tccggctatt cttggttcta
    10741 atgcaactaa ttttttcatc ttttctttcc tctttctttt ctttttatcc ttttacgccg
    10801 ccttcgacta aatcaccttt aataaatcgt tcagataacg catacataat gatgactggt
    10861 aaagcggtca ccaatgaagc ggccatcatt cgtccccaaa tgtagtctgg tgtactgaat
    10921 aatgtgttca aaccgattgg taaagtaaat ttttcggagg tcgacaggaa aatcgaagca
    10981 aataaataat cattccacga aaccataaag caataaacga agacagaaat gattccagaa
    11041 atagccaatg gtataatgat ccgaataatg atctggatcc ggctaagacc atcgatcatt
    11101 gctgcttctt caatatcagt cggaatcgtg tcaaaataac tttttagcat gaatatcgca
    11161 gtaggaagtg tttgaacgac catcgtgata atcagtgctg tattggtatc atacaaacct
    11221 agaccggaaa tgattttaaa taatggaaca acgatcaaaa taccggaaaa catataaacg
    11281 gtgtaaaagc tagcattgat tttcgagcga gctttgaagc gtagttttga caaagcgtat
    11341 gccccgctga tcccaatcac tactgcagtt acggaggcta tcaaggagat cactaaacta
    11401 tttttgaaat acatgatgaa tggaaaaatc tcagcattga aaatatcctg ataatgttca
    11461 aaagtccatt ctttcggaaa aatagtttgt gtcgttgcaa ttgcttcttg tgaatccttg
    11521 aatgatgtca tcagcatgat caaaaatgga aacaaattga cagctaatag caacaaaatc
    11581 gtcgcgtaaa ataagatttt cctgctcttt ttatttttca tttcaagtcc accttctttc
    11641 gtgagagcaa gacgaccgct gcaataatga tgaacaatag aatcgatata gctgctgctt
    11701 ttccaagatc attgaacgca aaggctgtct gatacaaata aacgcctaag atattgactt
    11761 tattcgtcag tagatagaca tctgtaaaca tatagaacat ccagatagat cgtaaaacaa
    11821 tcacagttgc tagtactggt ttgattgccg gcagtgtcac gatcttgaac ttctgccaag
    11881 catttgcacc gtccatttca gctgcttcat aaagcgtttt gtcgactgtt tgcaaaatag
    11941 ccaaaaatga aataaacgca tacggatagt atctccagat agcaaacaaa acgaccataa
    12001 agaagctagc aactggctgg tcgaaccaca gcggtgcttc gttgaaaagc tgcaacctat
    12061 ctactaacag atcattgacg attccataac tattattgaa catatatttc caagcaaaaa
    12121 tcaaagaaat agatggcgta acataactta ataaaatcag tgaacgcacc gttttcctaa
    12181 atctgaactt gcggttaagc aaaatagcta cggctaatcc taaagctgta ctgcctgcta
    12241 caactaagaa tgtgtaagca actgttaaac ctaaagaacg ataaaattca ctatcactta
    12301 aaatttcaag ataattgctt aatccgataa aaacggcgtc tgagttagga ttcagcggca
    12361 tatcgaaaaa actgatctga atattggaaa gcattggaat cagcactaaa acagctaata
    12421 aaagcatgct tggtgctaaa agtcccatgg ctaattttaa gtcagaatgt ttccttggac
    12481 gattcattga aacctccccc tgataatctg ccaatagcta tctacttttt tcgaacacca
    12541 ttggcagaac ttcttgttat ttcgtatttt tttgtgcgtc agctaaagct tgatcgacat
    12601 cttcgtttcc gacagttact tggttcactg cttttccgat cacacctgag cttgtgatat
    12661 ctcccatttt cgtgaaattc ttttccccga ctagtccaaa gacttgtact tcatcaaaag
    12721 cactagcaat ctcagatggc agctcgccaa aagacttgat gacttcattt tctttgtaac
    12781 catccagttc gactacttgt ttattcactg gttgagcacc accaggagac atcaagaccc
    12841 acttttccat gtttttcggt tgagataaga aagctgtgaa tgcttcagca gcctcttttt
    12901 gtttctcgtc tagaccagaa gaaatcgtca atccagatac tgtgccatag acagcttgat
    12961 ctttttgtgt tgggatagca aaaccgatat tttctgagtt ccccgcttca taaacagaag
    13021 gcaaaatgta agttgaatag attgccattg gtgctgttcc attcatgaaa gcatctttga
    13081 tttctgtcac atcattagag cctggcatcg tgtattggga taagttttga taaaacgaca
    13141 atgcttctct catcttttcc gtatcgatcg ttacctcgcc ttcatcatcc aaaacatttg
    13201 ctccatttga caaagcaaat tgagagaacg cttgctcact cattgttcct tcagcagtag
    13261 gcatagcaat tccatattgt ttattctctt tatctgtgaa atgttgagca atttttaaaa
    13321 tatcatccca attttctggt tctgaaaaac cagcttctga taatttttct ttgtcatacc
    13381 aaataccttg aacccagccg ctaattggtg cagcaatata gctttttcca ttttctgaac
    13441 gaacaaggtt tttggctccg tcataataat tatcttctcc agcttcctcg ataacgtttt
    13501 ggactgccgt ctgatcaatc agttcatctt tatccatcac tttagcaaaa tcctgactga
    13561 cttccattac ttctggtaat ttaccggaac gagctaacgt aacgattttt gtattgaacg
    13621 ctgattcttc taccggcact tgcttgattt tgatgtctgg attttctttt tcaaaatcag
    13681 caaccagttc attgatcaca cttaatcgtt cctgttcgac agaagagtgc atgaattgaa
    13741 tcgttgtctg ttgtgattcg ttagagcttt gactttcacc acaagcagta agaagaaatc
    13801 cagtagctag cagacaggta gtaacaataa tttttttcat ttttttccac ctcttatttt
    13861 attattttca gccacatata ttcatacggc tggaatatca actttcgttc ttgactgcaa
    13921 tggataattt gtccagaaaa caggtctagg taatctcctt ttggtaaaag ataacctgct
    13981 gattgattgg aaaaattatg gataactaag actttctctt ccttcgcttc gcgaataaaa
    14041 ctgataaaag aatctgctga gtccagtaag taaatcaaac tattcggatg gaaggctttt
    14101 tctttttttc gaatagatag catctgggtc aattcaccat atactgctgt tcttaatgga
    14161 tctgtctgca actctttctc aatatctgct aacaaaaatt tttgccgatt gatttttcga
    14221 ttctctcctg ttttttctac gcctttgtaa tcatttcgac ttcccagcac actttgaata
    14281 taaattgccg gcacgcctgg taacgttacc aaaaatgaat gagcagctaa aaagcgtttg
    14341 cttctccatt ccgtcgtatc tgttggagaa cttaacgcat ctagatacgt agcgtttatc
    14401 tcatatggac tggtcgttcc atctgggttt ttcttgtagt ttactcgggt accctctttc
    14461 ttcagctgtt ccactaattc aaggatcgtt ttttccggca gaatacctcg taccggattc
    14521 aatccgatac cgtcatggga ggctaaaaaa ttaaaaaaag ttgttttttt cgatgcgaaa
    14581 tcgatggttt ttaaccattc tttcaactta cttgtattac ccgaacgaat cgcttgaagg
    14641 gtcaaaggtg gtagcgaaaa ctgatagacc atctgtgctt cattctcgcc attcccaaaa
    14701 taactgatat tatctttgtg tggcacattt gtctcagtga tcaataccgt tcctggagct
    14761 gcttcatcag cgattgcacg gaataattgg atgattttat gcgtttctgg caggtgtata
    14821 caagaagttc ctagttcttt ccataaaaat cccacagcgt ccaagcgaat aaatgaagcg
    14881 cctttttcta agtaaaacaa aagaatatcg atcattttca ataaaacttc tggattttta
    14941 aaattcaagt ctacttgatc ttcgctaaaa gtcgtccata cgtgtttttc tttcccgttt
    15001 ttgtcaatga acgttgtaag taacgggctg gtccttggtc tagtcacgct gcttgtatct
    15061 gtatccagtg gcaaatcaat aaaaaaatct ttgtacgtat cattcaagtt taaatattcc
    15121 tgaaaccaag tactttcggc agacatatga ttgcagacaa agtcgaacat taaccgtgtt
    15181 tcgcttctca tttcttctat atcttcccat gtgcccaaac ggtcgttgat tgcctgataa
    15241 tttacaacgg agaaaccatc atcagatgta tatgggaaaa atggcaagaa atgtacaact
    15301 ctaaatgtat ctgccaaata cttttgataa aatttcttaa atgtacgcaa agttggttgc
    15361 tgctcttcaa aaaattgatc cccataagta atcaagaaaa tatcttcttc gtcccaatgc
    15421 agtttgcctg cctggccttt cttctgctga taaacactga ctttttgttc aatcatagag
    15481 gcggttttct cagacaaatc tgagtcgcga taaatcgctt gtaaaagttt tgtatacatc
    15541 ggattcccct ttcttttttg ggagcgttcc caacgatttg atcatattat ggaaaacgct
    15601 tactgtcaat agcatttttt taaataattt tgatatacac aaaaatacaa ataagaaagc
    15661 ttatgtatca ataattaata gcttcttaaa aaaatatggt ctctcatgat catgcaagct
    15721 attcctaaat tttcaaaatc atagacaaaa aagaatgtct attgtactat ggaattattc
    15781 taaaacgctc ccaaaaagga ggtgcatata aaattgaaac ctactattta tgacattgcg
    15841 aaaaaagcta atgtctcaaa atcaactgtc tccagagtat taaataacca gccaaatatc
    15901 tctgataaag caaaagcaag tgtacttcaa gcaatcaaag aattgaatta tgaaccgagc
    15961 aaaattgcaa gaggactgtc aggaaatggt tttgacgcga ttctagcatt atctcatcgt
    16021 acttctcata cgacctatgg caatcctttt ttttcagatg ttattcaatc catttctgcc
    16081 gtttctgaac aaaataactt cgacttgatt ctacaaacgg caaaaacacc agaagaagag
    16141 ctagaaaaat gcgcgaaaaa gatccaagaa aaaatgatcc gaggaattat tattttaagc
    16201 tctacgatgg atgaaacact tctttttgaa ttggatcaat acaatattcc tattgtggta
    16261 atcggaaaag tcggaaacga ctacacgaac atctactcag tggacacgga taatttccag
    16321 gatagttacg atttggtgga aacactgatc aagaatggac accgtcatat cggctgtctc
    16381 catgctccga cagaagttta tgtatccaat gatcgtctca atggttaccg tcaatgctta
    16441 tttgatcacc acctagatat ccgtaatgaa tggattatag acggcggctt tcgcttagaa
    16501 gatagcatgg cagcaatgaa tgatttaatg aagctacgag aaagaccaac tgcgattttt
    16561 tctaccgatg cattaaaatc attgagtatt tacaaagtgg cagaacaatc tggaaagcag
    16621 atacctgatg atctttcgat cgcaggattc agtgatccct tattgtcctc cctattttcg
    16681 ccacagttga ctcggataga cattccgaca aatcagttag gaatcaaagc cacagaactt
    16741 ttattccaac taatccacca ccaataccct gaagaaaaaa gaatcattct ttcaaccgag
    16801 attactctca cagattcgat ccaacaacaa gaaatgtaga acagaattat aaaagaacag
    16861 aaacactgag gataagtcag ttactctgtt cttttttcaa tcactcatcc ctcgttaccc
    16921 cctcccggta ttttagcgaa tttttcttat tttccatctg ttttagatag ctgtggataa
    16981 ctataatgtt tgtgttaaac tattttttcc acagggaaga aaaaactatt tttaaccacg
    17041 ttgtgtataa gtttttatag ttcgtttttt taaacacatt tacccttatt tcaatccatg
    17101 ttatttgggg atacttatct ctaaaacata aatagaataa cagacatgtc tactggtttt
    17161 gttttattcg aggaattatt caataatagc tagcaaaata ttaaaaataa ccgctctatc
    17221 ttcccatcaa tttattttgc attcaaaaaa tgatctatct ttacttttgt tgattgactt
    17281 ctcttggaag atgatcgttc cgatacctta attggatacg aaccgatgtt gttaagatcc
    17341 tttcccactt ttcttctagt tagacaaatt attttagaca aaccaaaaaa gaggttgtga
    17401 caataatttg tcacaacctc ttttttaaaa tatctatttt gtttgattgt tcattgcgtc
    17461 ttctgcagcc atttgcgctt caatatctga aatactgtag acattttcgc ttgctacacc
    17521 gacttctttt ggttccatgt cacgataacg ttgcatacca gtaccagctg ggatgatctt
    17581 acctataata acattttctt tcaaaccaag aagaggatct ttcttaccgc ggatcgcagc
    17641 atccgtcaag acacgagttg tttcttggaa tgatgcagca gataagaaac tatttgtttc
    17701 taatgatgct tttgtgatac ctagtaagac aggtcgagaa gttgcaggaa cgcctcctga
    17761 gactagcgta ttgtagtttt gatctttaaa gtctgcgatg tctaataatg tacctggtaa
    17821 gatatctgta tcacctggat ccattacacg aactttacgc agcatttgac gaaccattac
    17881 ttcgatatgc ttgtcgccga tttctacccc ttgcatacgg taaacacgtt gtacttcacg
    17941 aagcaagtag ttttcaacag ataatacatc gcgaacttgc aacaattgtt ttggatcgat
    18001 tgatccttct gtcaatggtg caccacggtg gatcatatcg ccttctgcta ctttcatacg
    18061 tgctgtataa ggaacagtat acgtacgtgt atctgttttt cctttgattg ttacttcttt
    18121 ggtacgtgtt gcaggatctt ctgagatatc gatgacatcc cctgttactt ctgtgatcac
    18181 tgcttgccct ttcggattac gtgcttcaaa gatttcttgg acacgaggaa gaccttgagt
    18241 gatatcgtct ccggcaaccc cacctgtatg gaatgtacgc atcgtcaact gagtaccagg
    18301 ttcaccgatt gattgagcgg cgatcgtacc aactgcttct ccgacttcaa cgtcagagcc
    18361 agttgcaagg ttgcgtccgt aacaatgttt gcagacacca tgttttgtat tacatgtgaa
    18421 gacagaacgg attgtcactg tttcgacacc tgcatcaacg atttgttttg cgatgtcttc
    18481 ggaaatcaat tggtttcctg caatgatcaa ttcatttgtt tcaggatgac gtacttcttt
    18541 acgggtgtaa cgtcccacta aacgatcttc taatgattcg atgatttcat ttccctcgcg
    18601 gatggcttgg atttcaagac ctcggtcagt accgcaatct tcttcacgga tgattacatc
    18661 ttgggccacg tcaaccagac gacgagtcaa gtaacctgaa tcggcagtct tcaaggctgt
    18721 atcggtcatc cctttacgag ccccgtgagt tgagataaac atttccaaga cggatagtcc
    18781 ttcacggaag ttcgaaatga ttggcaattc catgattcga ccattaggag cggccatcaa
    18841 accacgcatt ccggcaagct gtgtaaagtt ggaaatgtta ccacgagctc cagaatcaga
    18901 catcatgaag attggatttt tcgcttccaa accttccatc agtttttgtt ggatgctgtc
    18961 ttttgcagca ttccaaacag caatgacacg ttcataacgt tcgtcatctg tgatcagacc
    19021 acgacggaat tgttttgtaa tagtttcaac ttgtttatgg gcattttcaa tgatttcttg
    19081 tttttcattc agtacactga tgtcagcgat ccctactgtg ataccggcat gtgtcgaatg
    19141 tttgtaccct aagtctttca tacggtcaag catcttagaa gtttctgtta ctttgaatcg
    19201 tttgaagact tctgcgatga tgtttcctaa gtttttcttc ttgaacggta atactaattc
    19261 ttgctctttg atatgtgcag gaatatcagt accagcttca acaaagtatt tgtccggtgt
    19321 ttggacggtc aagttgaagt ctgttggttc attcagataa gggaattcag gaggcatgat
    19381 ctcgttgaag atgatcttac caactgttgt gatcatcgta cgttcttttt gccattcagt
    19441 aaatggtttt tcacctaatg agttagggtt cacaccgata cgtgaatgta aatgaacata
    19501 tccgttgcgc catgcgataa cggcttcgtt ttgatctctg aagaccattc cttcgccttc
    19561 gcgtccttct tcttccattg tcaagtagta gttacctaga accatatctt gggaaggagt
    19621 aacaactggt ttaccatctt tagggttcaa gatgttttga gcagctaaca tcaacatacg
    19681 tgcttctgct tgtgcttctt cattcaatgg aacgtggaca gccatttggt ctccatcgaa
    19741 atcggcatta taagcttcac atacaagtgg atgcaaacgg attgcgcgtc cttgtactaa
    19801 aactggttcg aatgcttgga taccaagtcg gtgaagcgta ggtgcccggt tcagcaatac
    19861 tgggtgttcc ttgattacgt cttctaaaac atcccatact tcgtcttctt gacgttcgat
    19921 tttacgtttc gcatttttga tgtttgaagc tagttcgcgt tgaacaagct cacgcatcac
    19981 gaatggtttg aataattcaa tggccatttc ttttggaagt ccacattggt acatcttcaa
    20041 gaaaggtcca acaacgataa cggaacgacc tgagtagtcg acacgtttac ctagcaagtt
    20101 ttgacggaaa cgaccttgtt tccctttcaa catatgagaa agagatttca atgggcggtt
    20161 acctggtcca gtaactggac gtccgcgacg accgttatcg atcaatgcat ctactgcttc
    20221 ttgcagcata cgtttttcat tttgaacgat gattccaggt gcattcaagt ctaacaaacg
    20281 tttcaaacgg ttattacggt tgattacacg acggtaaaga tcattcaagt cacttgttgc
    20341 aaaacgtcca ccttctaatt gaaccattgg gcgtaaatct ggtggaataa cagggataac
    20401 gtccataacc atccagcttg gttgatttcc tgaagcgcgg aatgcttcta aaatatccaa
    20461 acggcggatt gcacgtgtac gtttttgtcc ttgtgcagat ttcaattctt ctttcaattc
    20521 ggctgcttct gcatctagat caacattatc aagtaattgt ttaatcgctt ctgcacccat
    20581 agcagcttgg aattcttgtc catattgttc acgtttttcg cgatattcgc gttctgtcaa
    20641 caattgtttt ttctctaaat tcgtatttcc tggttcgatg actacatatg aagcaaaata
    20701 aatgatttct tccaaagcgc gtgggctcat gtctaataca agacccatac gtgaaggaat
    20761 ccctttaaag taccagatat gtgaaacagg agctgctaat tcaatatgtc ccatgcgttc
    20821 acggcgaact ttcgaacgag taacttccac tccgcatcga tcacaaacga ttcctttata
    20881 acggatacgt ttgtattttc cgcaggcaca ttcccagtct tttgtaggac caaaaatccg
    20941 ctcacagaac aacccttcgc gttcaggttt taaggtacga tagttaatcg tctcaggttt
    21001 ttttacttca ccgtaagacc agcttctgat tttttcggga gaagccaaac ctatttgcat
    21061 actttcgaat ttatttacat cgatcaaaag gggttccctc catttcattt aatggcaaac
    21121 cgcaagacgg ctgatcttcg accgccttgc agctcataga ccggattagt ctaaattatc
    21181 ttctgcggtt tcaaagtttt ggatgacatc gtctttttca tcttccactt gttcagcagc
    21241 tttcttttct aattctttgg cagtttgctg ttcggcaaat tttgtcaaag catcaacagt
    21301 gatcaaatcg tcgtcttcat cgtccatgtc gcgaagttcg atctctgttt cttcgatatc
    21361 caagacacgc atgtccagac ctagtgattg caattctttc accaatacgc ggaatgattc
    21421 cggtacacct ggttttggaa ttggttcacc cttgacgatt gcttcgtatg ttttcacacg
    21481 tccgactacg tcatctgatt tgtatgtcaa gatttcttgt aaagtataag ccgcaccgta
    21541 agcttccagt gcccatactt ccatttcacc aaaacgttgt ccaccaaatt gagctttacc
    21601 tcccaatggt tgttgtgtaa ccaatgagta aggtccgatt gaacgtgcat gcaatttgtc
    21661 atcgaccatg tgagcaagtt tgatcatgta catcacaccg acagacacac gtccatcaaa
    21721 tggttcacct gtacgtccgt cgtacagaac agttttcgca tcgctggcca taccggcttc
    21781 acgaactgtt tcccatacgt cttcatcact tgcaccatca aatactggcg ttgctacgtg
    21841 gatacctaac tgacgtgcag ccatacccaa gtgtaattcc aatacttgcc cgatgttcat
    21901 acgtgaaggc acccctaaag gattcagcat gatatcgatt ggtgttccat caggtaggaa
    21961 tggcatatct tcttccggca taatacggga tacaacccct ttatttccgt gacgaccggc
    22021 cattttatcc ccttcatgga ttttacgttt ttgaacgata taaacacgaa ctaacatgtt
    22081 tacgcctggt gacaattcat ctccagcttc acgagtaaag attttcacat cgtgaacgat
    22141 accgccgccg ccatgtggta cacgtaatga tgtatcgcgg acttcacgag ctttttcgcc
    22201 aaagatcgca tgcaatagac gttcttctgc agataattct gttacccctt ttggcgtgac
    22261 tttccctaca agcaaatcgc catcttggac ttctgcacca atacggatga tacccatttc
    22321 gtctaaatct tttaatgcgt cttccccgac attagggatt tcgcgtgtga tttcttcagg
    22381 tcctaatttt gtatcgcggg cttctgattc atattcttca atatggatag aagtgtatac
    22441 gtcatctttt accaaacgac ggctcatgat gatcgcatct tcatagttgt acccttccca
    22501 agtcatgaaa ccaactaaaa cgttttggcc tagagccatt tcgccttgtt ccatagatgg
    22561 tccgtctgcc agagtatccc ctttttcgac tttctcaccc aaatgaacga ttggacgttg
    22621 gttgtagctt gttccggagt ttgaacgacg gaattttgtt acatcgtatt tatctaatgc
    22681 accgttgtcg cggcgtacgc ggatttcaga agcatcaacg tattcaacga caccgtcatg
    22741 tttacataac aaagcagctc ctgagtcatg cgctgatttg tattccatac cagtaccaac
    22801 ccatggtgct tgaggattga tcaacggcac tgcttgacgc tgcatgttgg cacccatcaa
    22861 ggcacggttg gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa cggcaactac
    22921 ttgtttaggt gatacgtcca tgtagtctac tttatcaata gatacttcta agttttcact
    22981 ttgagcacga gccataacaa cgtcttgagc aaatgttcca tcttcattca atgggctgtt
    23041 tgcttgggct acgatgtaat ggtcttcgat atcagctgtc aagtagtcga tttggtcagt
    23101 aacacgacct gtttcacggt ctacacgacg ataaggtgtt tcgataaatc cgaatttatt
    23161 tactttcgca taactggaca aactattgat caacccgatg tttgggcctt caggagtttc
    23221 gatcggacac atacggccat agtgggagta gtgaacgtca cgaacttcat aaccggcgcg
    23281 gtcacgagtc aatccgccag gtcctaaggc tgaaagacga cgtttgtgtg tcaattcgcc
    23341 aagagggttt gtttgatcca tgaactgtga caactgagaa gaaccaaaga attctttgat
    23401 acttgccaca actggacgga tattgatcaa ttgttgaggt gtcaatgttt cagtatcttg
    23461 gatcgacatt ctttcacgaa ccacacgttc catacgtgct agcccgatac ggaattggtt
    23521 ttgtaaaagt tcaccgactg aacggatacg acgatttcct aagtggtcga tatcatcgac
    23581 attgccgata ccttccatca agttcaagaa atagctcatt gaagcaatga tgtcggctgg
    23641 acgaaccgtt tttacagctg cttctggata gccgtttccg atcacgttta cttcacgttc
    23701 agggtctctt ggtgaaaata ctttgatgac ttggacagtc attggatctg tgaccacacc
    23761 gtcttctgat ggatagtaag tcactgaatt taggccatta tcaatgaaag gagctagtgt
    23821 ttccatgact tggtgagtca gaactgttcc tttttcaacg atgatctcgc ctgtttctgg
    23881 atcaactaat gtttcagcta atgtcagatt caatagacgt gttttcaaat ctaatttttt
    23941 gtttactttg taacgaccaa cgtttgctaa gtcgtaacgt tttggatcga agaaacgagc
    24001 attcagcaag ttacgtgagc tgtctgctgt ttttggttcg cctggacgca aacgttcgta
    24061 aacgtctttc aaaccttctt ctgttcttga gtcgcttgcg tttttatgca agtctttttc
    24121 gactgtattg cgtaatgttt cgctgtcgcc gaagatttca aagatcgtat catcggaacc
    24181 aaatcctaac gcacgaacta atacggttaa aggaatctta cgtgtacggt cgatacgtac
    24241 ataagagatg tcttttgcat cagtttccat ttctagccaa gctccacggt tagggataac
    24301 agtagaaccg aatccttctt ttccgttttt gtcgactttt ccatggaaat agacacctgg
    24361 tgaacggact aactgagaaa cgattactcg ctctgccccg ttgatgatga atgttccttg
    24421 ttctgtcatt aatgggaaat caccgaagaa tacttcttgt gctttgattt cgccagtctc
    24481 gcggtttgtc aaacgcaatg ttacatgtaa tggtgcagag tagtttgcat catgcgcacg
    24541 agcttctgct actgtatact ttggttcttt caattcataa tctacaaatt ccaaagatag
    24601 attgccattg aagtcatcga ttggcaaaat gtcttcaaac atttctctaa gtccctcatc
    24661 taagaaccat tggtaagagt ctgtttgaat ttcgatcaaa tttggtaatt ccaacacttc
    24721 actgattctt gcgaaacttc tacgttcgcg atgttttccg tattttacta cgtgtccagc
    24781 caagctcttc acccctctaa aatgtcattc aaaaagacta cccgatcaat tgttacaata
    24841 atatttcaaa tattattttt aggtaacaac agacattttt tgcggctttt aggcaaaaaa
    24901 aaaccaaaaa tagaacattc tcttgaaacc ttacttcgtg agcttctact tttgtttcct
    24961 tatattaaag ccgaaacgga caatatttcg tttctgcctt ttcttcatca gatagttttt
    25021 gcaacttcat atactacact tattttctat aaaagtcaac acttcctggc gtttcttctg
    25081 ctttttcgca acattttctt aatgttttca attttatgtt ttcaattatc tgacaattct
    25141 taattgacag acctttttat ctcggttata ctttagaaaa ttcattttgt ggaggaactt
    25201 ctatgcgaac caacatcaac caaatcgcac caacacaact gaataacttt tactttagct
    25261 actttagata ggtttgtatt catcatgatg gatacaaacg ttaaacgaca gtttgtatct
    25321 atgatggcta aagaactttg tattgcagca aaaagccacg tagacaaaat gctaagtggc
    25381 tgagcagtga aaatacaaag taaaagtatc aagcattcta ctttttcaat ttattttccg
    25441 acttttcaat ccatttggac attttgtctg aatggatttt ttgtttccca aaattaagga
    25501 ggaaaaagaa atgaaaaaaa atataatcat cggattaggc gctgccctgc tactagcttt
    25561 aggaggttgc gcacaaaaag acaattccgc agaggcatca gatggacaaa aaacaattgg
    25621 cgtattgcaa cttgtacaac ataactcgtt agatgctgcc tataaaggat tcaaagaagg
    25681 attagcagaa gaagggtata aagaaggcga taatctaaca atcgattatc aaaatgccca
    25741 aaacaatcaa gacaacctga aaagtatgag tgagaaactc gtcaaagaag atcctgattt
    25801 gctacttgga atcgccactc cagcagcaca atctttatta aatgaaacaa ccactatccc
    25861 gatgactgtc acagcggtca cagacttgga acaagcccat ttagtcacat ccaatgaaaa
    25921 acctggcggc aatgtgactg gcacgacaga tatggtgcca atcgaaaaac aaatcggctt
    25981 actgttaaat atcgtgccag acgccaaaac aatcggcatc atgtataaca acggtgaagc
    26041 aaactctaag atccaagctg atttggcaga aaaagaattg aaaaaagcgg gcgtcaaagt
    26101 caaagtactg acagcaaatt ccacaaatga tgtccaacaa gtgacgaaaa gtctagctaa
    26161 agatgtagat ggaatctata ttcctactga taacacgttc gcaagtgcgg caagtgttgt
    26221 cggtgaagtc gcaaaagaaa caaaaacacc tgtcgttgct ggcgcagttg atcaagtcaa
    26281 agacggcggt ctagcaacag taggaatcga ctacgaaagc ttgggtaaac aaacagggat
    26341 catggcagca aaaatcttag acggcaagaa tccaagtgaa cttcctgtcg aaacagcgaa
    26401 tgatttggaa ctgtatgtca ataaagacat ggccaaagca ttaggcatca atccagacag
    26461 catcaaagaa gctgaataaa acacaggagg attctcatga caaatttgct ctctcttttc
    26521 ttatcatctg catcgcaagg ggtcttatgg gccctacttg cgattggtgt atacgtcact
    26581 ttccgtatct tggacattgc cgacttgact gctgaaggaa gctttccttt aggtgcaggg
    26641 atcgcggcag taagtattac aaatggctat catccattga cagcttgtct tctaggcttt
    26701 ttagggggtg cggcagcagg gcttgtttcc ggactgcttc acacaaaatt gaaaattccc
    26761 gcccttcttg cagggatcat caccatgact ggtttatatt ctgtcacatc ccgtgtgatg
    26821 ggtgcgccga acatctcttt attgggtcag ccaacgatct ttcattgggt cgagtcattc
    26881 ggcataacaa aagacaacgc tgtactgatc gtcggtctgc tttttgcttt gatcgttgta
    26941 tgtttacttg ttttgttctt acgtacagaa acaggacttg ctattcgtgc aactggcgat
    27001 aatctggcaa tgagcgaagc aaacgggatc aacacagata atatgaagat catcggttat
    27061 atgatttcta atggatgcat tgctctttct ggctccttgc ttgcgcaaaa caacggcttt
    27121 gctgatttaa attctggtat tggaacgatc gtaattggac ttgcttctat tatcatcgca
    27181 gaagttttgt tacgtaacca gccactattt ctccgtctct tgactgtcgt tttaggtgcg
    27241 gtcatttatc gttttatttt agcgttagtc ttcgaactga atgttgaacc aagtgattcg
    27301 aaacttgctt ctgctttcgt gctagtgatc tgtctttctt tcccgcagat ccagcaaaaa
    27361 ttccatttac ctcaaaaaaa gaaaggcggt agtgtcaaat gaatgacgtc ttaacattgg
    27421 aaaatctcca tcataccttt gaaaaaggaa cgatcaacga aaatcatgtc ctgaaaggca
    27481 ttaatctttc cttagatccc ggcgacttcg tgacgatcat cggtggaaat ggggctggta
    27541 aatctacttt gctgaacagc atcgccggta cattttctgt cgatcagggt caaattttat
    27601 tgaatggaaa aaatatcacg aaaaaatctg ttgtcgaacg ttcgaaatcc atcagtcgcg
    27661 tattccaaga tcctaaacta gggacagccg ttcgtttaac ggtagaagaa aatcttgctc
    27721 ttgctatgaa acgaggaaaa aaacgcggct tcttccgtgg tgtcaaacca caagaccgaa
    27781 catttttcaa agaccagctg gttcggctaa atttggggtt ggaaaatcgt ttatcctcag
    27841 aaatcggttt gctgtctgga ggacaacgtc aagctattac gttattgatg gccacattac
    27901 agcgtccaga actgatctta ttagatgaac acactgcagc gcttgaccct gctacttcca
    27961 aaacggtgat ggaattgaca gaaaagctga tcactgagca gaatctcact gcttttatgg
    28021 tcactcatga catggaagac gcgatccgct atgggagtcg actgatcatg ctgcatcaag
    28081 gaaggatcgt cgtagatatc cagcaagagg aaaaacagca gctcacagtg ccccaattat
    28141 tagcgttgtt caaacaaaac agcggcacgg cattaaaaga cgatcaagta cttttatctt
    28201 cataatcaga aagaggatgg gacaaaaaat gaacgcccac cctcttcttt tttctctttc
    28261 cttctttcgt ttttgcttta tgtatcaacc gttgtttctt cgaaaactat tttgttctct
    28321 ccttcttcct gatagaatgg atgggaaagg agcttgatgc catgacaacg aaagacaagg
    28381 tacttcaatt attgaaaaag acaccagatt ttctttccgg agaaaagttg gcacagcaac
    28441 tggaagtttc ccggacaagt atttggaaag ccatcaaaga attggaaaag gcaggctatc
    28501 gttttgagca cgggcctaca gggtatcgtt acctgccctc tgacgtacta gatgcaaaag
    28561 aaatccagca agagctacgg tcgtttattc ctgatttgaa agtacaaacg atgttgactt
    28621 ctgaatctac gatgaaagat gtcaaactgg cagcagctca aggagattct gtttcgaagt
    28681 tatttgttgc tgatacacaa gaacaagctc gtggacgttt tggacggcct tttttcgctg
    28741 aacctggacg aggaatctac atgagtctct tgctccatcc agacaaacgg tttgatgaat
    28801 tgcctcaata tacgatcatc gcagccagtg cctgtgtgaa agccattgaa tctgtaaccg
    28861 gtcgttctgc ttcgatcaaa tgggtcaatg atatctacat ggatggaaaa aaagtctgtg
    28921 ggattttatc tgaagcagtc agtgatatgg aaagcggcag gatcagtcat atcatcattg
    28981 ggatcgggct taatttttct gttcctcaaa atcattttcc agctgatctc caagaaaaag
    29041 ccatctctgt ctttcccgac ggacaagcta gtgtcacaag gaatcagcta atcagcaaaa
    29101 tctggcaaga attgttcact tatctttctc acccagaaaa agcgttggac ttctataaag
    29161 aaaaatcatt cgtattggga aaaaccgtgt cgttcaatca aaaaggaacg acttatgtcg
    29221 gtcttgcaaa agaaatcggt gatcatggcg aactgatcgt ccaaacaaat gaacagaaga
    29281 tgagtttgtc ttctggcgaa atcagtctca catctatccg tacgcaataa ttatcagatt
    29341 tcacaaaagg acacctgatc tcatacagtg tccttttttc tgaattctct tcaaaagact
    29401 ctccttattc tatcagctga cagtttctct atcctctaga aaaaggtatt ctaaaaatat
    29461 ctataaagca tggtacactt tctttaaatg aatcaatgca aaaaacaaga gagtcatcag
    29521 tttacacgat caaaagagat agcaggccgc ttcctttttc aatcttatag atagaccatg
    29581 ggtaacgata aaaacaaaaa agaacttgcg acttattttg ccgtaagttc ttttttagct
    29641 agtgccttaa tctcttaatc ccaacaaacg tctcgcatag atcacctgac cagagtgcat
    29701 agcagcatca tcaataatag aaacgagacg cattcctcgt gtgactggtg gtgtccagtt
    29761 ctcgtcaatt acttcatcta gctcggaagg ttccagcctt cttaagtaag aaatagcaaa
    29821 atcagcagct cctcgcaagt atcctagcag atcttctatt tgattagctt ggatctgctt
    29881 tgcttgttcc agactatgct tccaatcttg ttcgttatct gctatcgtca tcggaaaccg
    29941 gctttcccag tcttgactat gccaaattgg agaagttcct gctaaatcag caatctggaa
    30001 atctaattct cgagcggtat gccaagccag ccaagtcatt gatttgatct gcggggctct
    30061 atcttccact ggaaaacgat tggcctcctc aatagagacg ccttcaaaca aacgttcaaa
    30121 ccgatcgtat gcccgatcca cactctcgca tagcatatct aaataatcca tttattttcc
    30181 tcctttttat ttatcctact tactttttcc taattctagg atacctactt atatgttact
    30241 acacaccctt attttttaca ctttaacagt caccatcatc aatagtttgg agattgaaag
    30301 aaaaagatag tgtcgaacta tcaattgaac aagaagcaac aatatgaacg tttcattaat
    30361 attctttaaa taaacaatga tttttcaaac gaacagttta agactaggag aaaaagagta
    30421 taataggaaa atgtttgaaa ggaaaggaag gggaaaaatg aaaaaaaggg caagtttact
    30481 agtcctagtt gctttgttgt tcaatatctt ttcgtatggt gtggccgttt cagcggaaac
    30541 atacattcct aaagaccctg ggaatattta taatgatcta actggtaact atggcttgtt
    30601 aggaattgct agtcaattcc acgtatttgc taaaaataag acaactgtga atgcacatac
    30661 agacggaaat atagcaacac atgaacttga tgcaaaaaat aattttggta cagagcttca
    30721 tgaaggttta ttgaaccaag aaataaatta tatacaaaaa actgattctt tcgctaattc
    30781 ttcaggcata cctacaggta gcacaagaat gaataaattt gtcgttggca gtaacgtgga
    30841 tgtagcactt caagatggtc atcctacagt caatggatcc aggcttgatc acttaactcc
    30901 agatgatttt tataaagatc gtgctgggca tgaatatatt gatttcgagc aggaatttgc
    30961 taaattgaat gtagcagcaa atgatcttgc aacgatcact ccagctaaaa catatactgc
    31021 tgcagatttt ccagacatga acaatcggac aatcgattta actgatttat cagataccgg
    31081 gtttttattg gtaaatatcg atgcagaagt gttaacgatg aatacgccac ttcaaatcat
    31141 taatccaaat gatcaagtag ttgtatttaa tgtcatcaac agttcttctg cattgaacgt
    31201 acagtcacca atcaaataca atgatcgttc aaatcatgaa acagaagatt tttcggatgc
    31261 gaatatctct tggaattttg gaaatgagat gactgatttg acaatcagtg ctccttttca
    31321 aggaacaatc cttgcgccta atgctactat ccgcattact caaaaccaag acggaacgat
    31381 tataggaaca aatgtgattt tagatgcagc taccaatcgt tgggatccta acgaaatatt
    31441 tatcagcgac aatggtacag atacgacaga cacaagcgac agtacagata catctaccac
    31501 aagtgatagc tcagattcat ca
//
LOCUS       DADQCX010000025        31270 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.025, whole genome shotgun sequence.
ACCESSION   DADQCX010000025 DADQCX010000000
VERSION     DADQCX010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.025"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            169..1038
                     /locus_tag="J8R83_001085"
     CDS             169..1038
                     /locus_tag="J8R83_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAZ9574226.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1247..2272
                     /locus_tag="J8R83_001086"
     CDS             1247..2272
                     /locus_tag="J8R83_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAZ9574227.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKTVLPK"
     gene            2311..3261
                     /gene="manA"
                     /locus_tag="J8R83_001087"
     CDS             2311..3261
                     /gene="manA"
                     /locus_tag="J8R83_001087"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAZ9574228.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3355..5058
                     /locus_tag="J8R83_001088"
     CDS             3355..5058
                     /locus_tag="J8R83_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9574229.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5060..7093
                     /locus_tag="J8R83_001089"
     CDS             5060..7093
                     /locus_tag="J8R83_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9574230.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7104..7544
                     /locus_tag="J8R83_001090"
     CDS             7104..7544
                     /locus_tag="J8R83_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9574231.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7744..8871)
                     /locus_tag="J8R83_001091"
     CDS             complement(7744..8871)
                     /locus_tag="J8R83_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574232.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8874..9551)
                     /locus_tag="J8R83_001092"
     CDS             complement(8874..9551)
                     /locus_tag="J8R83_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574233.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9815..11581
                     /locus_tag="J8R83_001093"
     CDS             9815..11581
                     /locus_tag="J8R83_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAZ9574234.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11596..12033
                     /locus_tag="J8R83_001094"
     CDS             11596..12033
                     /locus_tag="J8R83_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9574235.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12046..13197
                     /locus_tag="J8R83_001095"
     CDS             12046..13197
                     /locus_tag="J8R83_001095"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAZ9574236.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13259..13957)
                     /locus_tag="J8R83_001096"
     CDS             complement(13259..13957)
                     /locus_tag="J8R83_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAZ9574237.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13950..15302)
                     /locus_tag="J8R83_001097"
     CDS             complement(13950..15302)
                     /locus_tag="J8R83_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAZ9574238.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15525..16925)
                     /locus_tag="J8R83_001098"
     CDS             complement(15525..16925)
                     /locus_tag="J8R83_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAZ9574239.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17086..17823
                     /locus_tag="J8R83_001099"
     CDS             17086..17823
                     /locus_tag="J8R83_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAZ9574240.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17948..18427
                     /locus_tag="J8R83_001100"
     CDS             17948..18427
                     /locus_tag="J8R83_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAZ9574241.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18424..19191
                     /locus_tag="J8R83_001101"
     CDS             18424..19191
                     /locus_tag="J8R83_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574242.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19421..19990
                     /gene="lepB"
                     /locus_tag="J8R83_001102"
     CDS             19421..19990
                     /gene="lepB"
                     /locus_tag="J8R83_001102"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9574243.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20094..20696)
                     /locus_tag="J8R83_001103"
     CDS             complement(20094..20696)
                     /locus_tag="J8R83_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9574244.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20802..21271
                     /locus_tag="J8R83_001104"
                     /pseudo
     CDS             20802..21271
                     /locus_tag="J8R83_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21377..21961
                     /locus_tag="J8R83_001105"
     CDS             21377..21961
                     /locus_tag="J8R83_001105"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAZ9574245.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21964..23037
                     /gene="prfA"
                     /locus_tag="J8R83_001106"
     CDS             21964..23037
                     /gene="prfA"
                     /locus_tag="J8R83_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAZ9574246.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23030..23869
                     /gene="prmC"
                     /locus_tag="J8R83_001107"
     CDS             23030..23869
                     /gene="prmC"
                     /locus_tag="J8R83_001107"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAZ9574247.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23862..24041
                     /locus_tag="J8R83_001108"
     CDS             23862..24041
                     /locus_tag="J8R83_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574248.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24063..25088
                     /locus_tag="J8R83_001109"
     CDS             24063..25088
                     /locus_tag="J8R83_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAZ9574249.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25263..26507
                     /locus_tag="J8R83_001110"
     CDS             25263..26507
                     /locus_tag="J8R83_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAZ9574250.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26660..27607
                     /locus_tag="J8R83_001111"
     CDS             26660..27607
                     /locus_tag="J8R83_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9574251.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27741..28370
                     /gene="upp"
                     /locus_tag="J8R83_001112"
     CDS             27741..28370
                     /gene="upp"
                     /locus_tag="J8R83_001112"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAZ9574252.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28509..28751)
                     /locus_tag="J8R83_001113"
     CDS             complement(28509..28751)
                     /locus_tag="J8R83_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574253.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28872..28944
                     /locus_tag="J8R83_001114"
     tRNA            28872..28944
                     /locus_tag="J8R83_001114"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28905..28907,aa:Thr,seq:cgt)
     gene            complement(29063..29701)
                     /locus_tag="J8R83_001115"
     CDS             complement(29063..29701)
                     /locus_tag="J8R83_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAZ9574254.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29824..30456)
                     /locus_tag="J8R83_001116"
     CDS             complement(29824..30456)
                     /locus_tag="J8R83_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAZ9574255.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30807..31106
                     /locus_tag="J8R83_001117"
     CDS             30807..31106
                     /locus_tag="J8R83_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9574256.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10673 a         5459 c         6291 g         8847 t
ORIGIN      
        1 aacagctttt tcacaacctc tttttataag agtttttact cattaattta caaaaaacaa
       61 gcaaaatgcg aattttctca catttttttt aacaaaatca aagttattgc ttgaaagaag
      121 aagaatccat cgttaaaata aagcttgacg tagaggggag caagaaatat gaaagatttt
      181 caattggggg ctgccaccta tttaaaaagt gtagccattc gggtgaaaga ccgagataaa
      241 atgattgatt tttacaagaa cgttgttggc tttgatttga aaagagaaga aaacgaatta
      301 gccattttag gaacagaaga agctggaagt gaaatgttgc tgctggaaga aagtcctaga
      361 gcgaatgatc acatgggggt gatcaaaaag ctgaaccgtt tttcattgat tatccctagc
      421 acagaagaaa tggcagatat cctttgtcgt atccgtaaaa tgaattatcc aatcaaagaa
      481 gctttagaag atcatggacg tatggggatt ttgctcgtag acccagaaga gaatgaattg
      541 gaaatttacc atgaagagaa taagaacgac caaagagaaa ttccagaaac aatggatcaa
      601 gaagcattat taagaaaatc tgaagaaaaa ttcagtaaac tatcaacagg ttcttatttt
      661 gaaaaaatcc atttaaatgt tactaactta acaaaagaac gccaatttct taatcatgta
      721 cttggtttga aggtacataa tgaagaagag ggcatccatg tattgaatga aggagatttc
      781 catgttggtt tgacagaagc tagcggaggc gcaattgatt tgcctacaga tgaagtgatt
      841 ggacttgatt ttctgaaatt catgatcgat actgaaagca tggaaggact gattgctcac
      901 ttgcagcaac tatcagttga tttcttctta gacaaaaagc acacagtact cacaatctat
      961 gatgctatag gaatcgaatg gtggttcgtc agtgagccaa aagaaaagaa taaaactgac
     1021 attcgatgcg acgcttaact ttttctttct taacgattgt cgcatgtctc gtcattttat
     1081 gaacggtcat actatcgctt attctagaga tagaaagaga aaatagtata ccgggggaaa
     1141 ctgcgcggtt tttcgcgcag tttttttgtg taaaaaaggt tgattcctca tagattaagc
     1201 tttaagcttg gactgtaaga atctgataga aaagcaggag aaaaagatgt atccacacac
     1261 gaaacagctt attttgaaaa agatggaaga aggattttat ccaggtgtag cagtcgcctt
     1321 cataaaagaa aatcaagtag aaacatttac agccggcttt gcccaagtcg ttcctgaaaa
     1381 gcagctgatg acagaagatc tgttgtttga tgcagcctca ctgacgaaag tcgttgcaac
     1441 cacttcatta gttttacgtc tattagaaga tggaaagata gaactcgatc aaccgcttca
     1501 taaatatctt cctgaatttg aaaatcagac aatcactttg cgtcatttac tgacacatac
     1561 ttctgatatc aaaacatgga taccaaacag agataagcta tctcaggaag aattgatcgc
     1621 cgcttatttg aagctagaac caggtgagca actaggaaaa gaagtaaaat atacagatgc
     1681 cggtacgatt cttcttgggt tgatgctaga ggaaatttac caagaaactg cagtggaaat
     1741 ctttcaagaa caagtattgg aaccattagg aatgatgaac agcttatttc ttccttttcc
     1801 ttccaaaaaa atcgttccca cagaacaact gccttcgggt gaggttttgc gtggacaaac
     1861 tcatgatccg aaagcaagag ttttggctga acatgcaggt aacgcgggtc tctttattga
     1921 tttgaaagac agcattactt ttgtccaaat gtatttgaac aagggaaaaa tccgtaatgg
     1981 tcgtttttta gaagaagaga cgattgattc tttactgcaa gatcaaacac cgaaaaaaaa
     2041 tggctatcgt tctttaggat gggacttaaa aaaggatgta gaagacggtc atgcgattct
     2101 ttttcatact ggttatacag gtacgttttt cttgattgat ataaaaacac aagaagcgtt
     2161 gatatttttg tcaaatcgcg tacatcctgt cgatcatcgt gcggagtatc tcatatgtcg
     2221 agatgaaatt gttgaaaact ttttgaaaga gaaaacggta ttaccgaaat aatgctataa
     2281 tagctatgaa aaatgagagg agtttgaatt atgcaggaac ctatgttttt aaaaccagtt
     2341 tttcaagaaa aaatttgggg aggaagtcgt ttacgttcag tctttggttt tgatatccct
     2401 aacgataaaa tcggagaaga ttgggcgatc agtgcgcatc ctcatggtgt cagtgtagta
     2461 gaaaatggcg aattcaaagg gaaaagatta gatgaactat ggtcagaaca caaggaattg
     2521 tttggccatc cttcagaacc agtgtttcca ttattgatca agatcttaga cgcagaagat
     2581 gatctatctg tacaagtaca tccagatgat gcctatggga tgaaacatga aggtgaatta
     2641 ggaaaaactg aatgctggta tatcatcgat gctgaacctg gtgcagaaat catctatggt
     2701 catcatgcaa agacaagaga agaactagct gagatgatca aagatgggcg ctgggatgac
     2761 cttttgaaga aagtaccagt taaaaaaggt gatttctttt atgtaccaag cggaacgatc
     2821 catgctattg gtaaaggaat catgatttta gaaacacagc aaagttctga cacgacttac
     2881 cgcgtgtatg actacgacag aaaagatgcg caaggacaaa caagagagct gcatatccaa
     2941 caatcgatcg atgtaacaac tgtccctgcg aaaacaccag aattacaaat caaagaagtc
     3001 cgaaaaggga attcatcgat cgtcacttat ttagaaactg agtttttcaa tgtatatgag
     3061 tgggatatta aaggaatcac atctttcaaa aaacaagccc cttatacatt gatgacggta
     3121 atcgaaggag caggagacct tgtcgttgac ggaaaaacat atccattaga aaaaggaaca
     3181 agctgtatta ttccaaatgg cgtttctgag tgggcggtcc aaggtgaact agcaatcatt
     3241 gcgactgaac caggcaaata gttcccagat agctgaaagc agcagacggt ttttcgtttg
     3301 ctgctttttc tacataaaat ccgtccatca ataaatagaa gtctggtgaa aaagatggaa
     3361 tacaaatgga aagcaaacaa cagcagtcgc gtgtctatga aacaactgag aaaagctgga
     3421 catcacttaa atgaaatgat catgccaaat ctaagtctgt ttatcgcttg gggaatcttg
     3481 tcattagcaa caaaaggtgt gtctggcgat ttgcacacca cattagaaga ggtatgccat
     3541 tggatgatcc agctgctttt acccatcttg atcagttatt caggcgggaa atcggtaggg
     3601 ggacaaaaag gggcagtcgc cggtgcaatt gcttctttag ggttgatcgc tcgttccaat
     3661 gctccacaaa tcgtaggagc gatgattatc gggccgcttg ccggcatcgt atatgaacaa
     3721 tttgtttcta gattccacgt gaaattcaag gctggatatg aaatgcttgt cagcaaccta
     3781 ctagtaggac tgactggtag cgttatttgt ataattggaa tcgtttttat tgaaccagtt
     3841 ttaaatagtg ttcacttgtt gctcgcctcc gttgtgtctt ggctagtcac aatgaatctg
     3901 ttaccacttg tcagtctgat cttagaacct ctaaaagtac tatttttcaa taatgcaatc
     3961 aatcatggtg tattgacacc tttaggaatc gaattctcac aaacagtcgg gtactcttcc
     4021 ttatttttga tggaggcaaa tcctggacct ggtttaggga tcttactttc tatcctttgt
     4081 tttgcagaaa aacaggaaaa agtaaatgcg agtggagcat tgatgatcca tgcgattggc
     4141 gggattcacg aaatctattt tccatttgtc ttgctgcgac cgtatctatt tttagctgta
     4201 atggctggtg gggcaagcgg cacgttgata tttcaatggt tagatacggg attagctgca
     4261 cctgtatcgc ctgggtcact actcgtgatt tttgccaatg cgccttatcc acaactagct
     4321 ggggtaagta tagggatagc aatcagtaca tttgtgacct tcatttgtgc agcgatacta
     4381 ttgaaattac caaataaaga aaaagagaac aaaacggtca aagaaagggg agaaatcttg
     4441 gaaccatcta tcattcattc cgtcattttt gcttgcgact caggtatggg atcaagtgct
     4501 atgggagccg ccctgctgaa aaagaaatta gcagcagaaa aaatcgatct ttctgtcgga
     4561 tacagctcta tctatgaatt gaataaccaa gtaaatcagc tggttatcgt gcaacatgaa
     4621 ctagcgggtc ttgcaagaga aaaagtacct caaagtcaaa tctatgtact ggatcacttt
     4681 ttggaaacag atatcttgct gtcacgaata aaagaagcga tccaatttcc aaagcgggaa
     4741 gaaaaaaaag agatagcaga tatcacagaa caaaaaaagt cgcctgctaa tattgtattt
     4801 ttgtataaaa acaacagacg cggctcacaa actatgggca tgacgatttt aagtcaatta
     4861 gcaaaaaaag cgaaaaaaca gtttgttatc tcaaaagaat caatagaaaa aatcaaaatc
     4921 caagaagaaa cgatttatat cgcacaaaga gaactagctg taactgaaca gctagaagaa
     4981 aagatccctc ggctagttct agttgaacat tgggtagcta cgaatgaata cgaaaaactc
     5041 gtgaagggag aaatataaga tgtatttatc gcccagagaa aaacaattat tagcagaatt
     5101 tctcagtagc ccgtcacctg tatctatcca aaaaatgatg aatttattga aggtcagtaa
     5161 acggactatt taccgcgaat tagataatct tgaagtctca ttgaaatcgg taaatgcttc
     5221 tttgaaaaaa gcagctagag gctcatttgt cattgaggca tcagaagaag tattagagca
     5281 attaaaagaa aatacagatg ggaaaagtaa tgacttatcc actgctaaac gacaacacgc
     5341 gattttagcc gagttgttac tgacgacaga gccgttgagt cttgctcatt tcatggaatc
     5401 atatcgcatc agtaatacca ctttttatgc agatatcaaa cagttggaag aaagtattcg
     5461 ccaactgcct ttggaaatca ttcggaacca gggatacgag atcgaaggac cggaaaaata
     5521 ccgccggctt ctgacagcga atgtattaga attagaaatc aatgaatatg aactttttca
     5581 tagtatttct ttcgatgcat cactgaatta tttttttcga ttcgttgatc cgcaacatct
     5641 atctcttgca cgcaaagtaa tcggggaaga attgatccaa aaaaagacca atctaagtga
     5701 tagaaagctt gaacatttgg ttttgatgct gacattgacg atggagcgtg tgactaaaaa
     5761 tcatttactg acaaatgaga catataatag tctggcaaac aaagaattac tacagacagc
     5821 taaacgattg ttttcacgga tcgcttctga gacaaaacaa ctttatccag taaatgagat
     5881 cgtctttttt gcaggattat taaatgactt cacgaactca tttgatcaga atttctttga
     5941 agagacgttc gatacacagc ttgcttattt agtaaaacaa ctgattcaag aagtaagtga
     6001 agagacgaat gtccattttt atgaagatga aactttgtac aaaatgctgt tgactcattt
     6061 atctggtgtg ttttcaagag ccgttttaca agaagagaca ctgaccaatc cgattttaga
     6121 aaaaatcatg gttcaatacg aggaagttgc gaatgcaatc cgtaaagcag tagagcggat
     6181 ttttcaagaa aaaaaattat ccgaagaaga gatcgcttat atggtccttc attttgcgaa
     6241 ttcattggaa cgaagtccga aagaaagcaa tatcagtatt gcaggatttt cgccaagtgg
     6301 attagcttct actagcatgt tggaactacg attgaaaagg tattttccct tcatccaaca
     6361 aattcatttc tatcggattg ctgatttaaa aaaaatcgat ttacaagaag aatatgatgt
     6421 tgttatttct acatctattt taccaggata cggtggaaaa tatattttag tctccccgct
     6481 actgctagaa gatgaagtca agcagctaaa agaagctttt tcgcatattg agaagaaaaa
     6541 aaggcaaaaa attacgtata acagcaataa cgagtggatg atagaagata cttatgagga
     6601 aacaatgcat ttcatggatc aaatcaatca attactcggt cgttttttta tccaagaact
     6661 ggataatcct gagacgattt ccgaaacgat tcgcagctta tttccttatt ttcctgaagg
     6721 actagtaacg gatgaagagg tggttcatcg ccggctgctt aagcgatatg aacaagcacc
     6781 tatcggtatt cctcatacaa atatggggtt attccataca tccagctcat tgatttctaa
     6841 accgatcttt tgtattttca atttgaaaca tccgttgacc attgaaggga tggatagaca
     6901 gccagtcgat ttgtcccgta tgttagttat gctggcgcct tcgccaatcc aagaaaaaga
     6961 cgggattctt ttaggaaaga tcagtggagc aatcatcatg aatgacttga acaccgagat
     7021 cttccgctca ggaaataaag aaatcgttta tcagttgtta gcgaaaatcc tgattgaaga
     7081 aataaagaaa tgaaggtgaa aagatgatac agctaccagc agaaaaaata ttgctcgatc
     7141 aatcctatca aaattggaaa gaagcgttga ccgagatcgg ccagtggatg acccaacaag
     7201 ggggaatcaa accggcatat atccaatcaa tgatcgaaag acaagaaaaa gcgagtgtct
     7261 atatcgggaa tttcgtagcc ttgccacatg ggactgacaa agatgaagaa gtagtagaag
     7321 aaggaatcta tttagtccaa gtgcctgatg gtgtggactt tggaacaaaa gaggaaccaa
     7381 aaatcgcgac actcttattt gtagtggctt taaaaaaaga acatcagtta gcggtgctcc
     7441 aagatttagc ctttttctgt tcagacatcg accaagtaat ggcgctcagt gatgcgaaaa
     7501 ccattgaaga agtccaaatg atttttgaac atggacatat ataaccaatg ttcacagtaa
     7561 aaaaagctgc cttgcatcaa gtaataactt caaccaagat aaaaataaga ggagctattt
     7621 ttgttgggag gttcttatta ctgcggatgc aagcttttga aaactattta ttctagaaaa
     7681 ccgtttattt gaaatagggg acggtgacaa ggtttttgtc accgccccta ttatttttgt
     7741 gttttaatag ctctttttta tatagatagt gcccatacct atgaataata aaacgatact
     7801 ccatatacca agtgtcaaga taccattcat gaaagtaacc tgttctgaag ctagtggcga
     7861 gaaaatatct cctcctatga tcacattttg aaaatcaaca taagaagttg gcaagtaatg
     7921 actgattgat tctatccatc caatcgaaga aaacaagcga tactctgcta agaaaagaca
     7981 aagaagtgta cctaaaagat tgactagaga atgttcaaat aaagcagata gaagaaaact
     8041 gattgtactt aaaaagagca cccacaacaa caggaacaga aagctctgga aaagatactc
     8101 atacatcgga aggattcgta tctcctgacc aatgatcgtt cctacaggat aacggaagtc
     8161 tcccaaacca tttttgatta ttactagtat agagacgatc aaaaatggca tcacgagact
     8221 tagcatagct gcaccataat aaatggtaaa acggatgcta tgtttcttta ccatactatc
     8281 cggtaataga ttgactagag agattacctg ctttcttttt tcataagaga tgatggaaga
     8341 aagaaacaag gcggttatac ataaaatcaa aaaactagaa atcattcctg aaaaaatatt
     8401 ttcgtagtaa tttgctaaag ggagatgcgc tggcaagtca aaaatagaat atctttggat
     8461 ctgatgttct ttcatataac ggagcaactc gacacgtttt tgttgttcaa tgattggaat
     8521 tccttgtctt tgaccagaaa tcagtcgatc cagtatatct ttttcataat gataagttgc
     8581 ttcgaccatt tgctggacat tccctgtgtt ttttgcatgt aagattgctt cgatcagttt
     8641 gttgcttttc tctaaacttt ccacaaattc tttctcattc tcatcttctt tcaacgtttc
     8701 aatcaaacgt tgcatctctt catagttatg attcagttca tcgaattctg tataagcaag
     8761 tttatgatca aaaaaaagtg ggaatgcaaa gagcacgacc aacaatagag gaaataaaaa
     8821 gtttactttg ttttttagta agagattgcg ttcaaatgta agtaaagaca tagttacacc
     8881 tcatataatt tacgataaat agctaaaatc tcttccatat ttgaggattc tgtgacgatt
     8941 tctccatttt ttagaaaaca tgctttagaa caaatcgatt ggatattcgc gatagcgtgg
     9001 gaagaaagaa gaatcgtctt cccctctttc tgccattgtc tgatgaggct attcaagata
     9061 tcaatacttc ctgggtctaa tccgttcaac ggttcatcga ataacatgac agatgaatca
     9121 ctgatcaagt aagcagcaag caagacatgt tgtttcattc ctagagacat ttttccaatc
     9181 ggcaaagtaa ggtactcagt catcttcaat cgttggaaaa cagtttggca ttctactttg
     9241 ctctgccaat agtatttgat caaagtcaaa taatcaacag ccgatagata gtcggataac
     9301 tgattcgttg attctagaaa aaagaaagac cggcgataat ctgtataagc agtaggagag
     9361 atgttgtgaa gggacaattg atcataagtt gttggcagca gttgggcaat gccattcagc
     9421 aaagttgttt tgccaaatcc gttcggggca atcaaagcag ctacttctcc tgattctact
     9481 aaaagattca attgtcgaat cacacgtttt ttaccacgtt tcatgttcat gtttttgatc
     9541 agtaatgtca tagataggcc tccaatataa aatttaataa cataatagaa tggaaaacat
     9601 ctaaattaaa tgctaacaaa agttattgtt tgcatattat aaaaaaatta aaataacagt
     9661 tttatttaaa attgaagttt tctgataccg aaatcttttt attttgctga catactcaaa
     9721 cctttggcac aaagtttcgt gccaaagtac gactatttct ctttttagta agcggataca
     9781 attagagtat caaaaggaga gagggagaga caaaatggaa cggacgattc ccaaaaacaa
     9841 catttcgcta aaagcgaggg tacaaaaatt aggcagtact ttatcaagca tggtcatgcc
     9901 aaatattgga gcactgattg cctggggtgt attaacggct ctatttatcc cagatggtta
     9961 tttaccaaat gaggctttgg ctaccatggt aagcccaatg ctaacttatc tgattccttt
    10021 attgatcggt tatactggcg gaaaagtaat tgctggtgac cgcggatcag ttgttggggc
    10081 aattgcaacg atgggtgtga ttgtcggaac agatattcca atgatgctag gcgcgatgat
    10141 catgggacct cttggtggat atgccatcaa gaaatttgat cagctattcc aaaaacggat
    10201 caaatccggt tttgaaatgc tagtcaataa tttttcagca ggtcttatcg gttttggatt
    10261 agcgttatta ggtttttctg cgattggtcc agttgtcgat gcattgactc aagcaatggc
    10321 aaaaggtgta gagatcattt tatctgccca tttgattcca ttgacaagta tttttattga
    10381 accagcaaaa atcttatttt tgaataatgc aatcaatcat gggattttga caccattggg
    10441 aactgaacaa gtagcagagg ctggaaaatc tattctattc ttgcttgaag caaatcctgg
    10501 tccaggactt ggcgtattac ttgcttttac tttgtttggc aaaggagcag caaaatcttc
    10561 agcaccagga gccatgatca ttcacttttt aggcgggatc catgaaatct attttcctta
    10621 cgttatgatg aaaccgttat tattcttatc agttataggc ggaggaatgt caggaagttt
    10681 cattttccaa ttgatggatg ctggactaag agcgccagct tctccagggt cgatcattgc
    10741 gattctagcg atgacaccgt tcaattctta ccttcctgtt attttgggcg tgattgttgc
    10801 cgcagctgtt tcgtttggta tttctgcagt aattttgaaa gcggatgcga aagatacaaa
    10861 tgaagacttc gaaaaatctg ttcaagagac aaaggcagct aagcaagctt ccaaaggtgc
    10921 ccaaggtatt cctcaaggag ctacattctc tggcgtacaa aaaatcattt ttgcttgtga
    10981 tgcaggaatg ggatcaagtg cgatgggcgc ttcgatcttg agaaaaaaag tacaggaagc
    11041 agacttgcct caaacggtga ccaatcaagc aatcagccaa ctgacagatg actcgaatac
    11101 attgatcgtt actcaggtcg aactacaaga aagagcaaaa caaaaagcac cgagcgcgcg
    11161 ttttgtctca gtagaaaact ttttgaattc acctcgatat gatgaaatca ttcaagaatt
    11221 aagcagcaag cagaaaacat cagtttctga aattgagaat gagccagcag aagagtttct
    11281 ttcagcaaac atcaaacaaa tcaaagagat tctacttgtc cacgatgatc gttccggatc
    11341 agcaacaatg gggatgaccg tgctcaaaga tatattagac aagaaccatt taactatccc
    11401 gttaagaaaa gtcaatatcc aagatttaaa agatgaacct gattcactga tcgtagccaa
    11461 agaaagttta gcggaaaaag tacagatggc tgcacctcaa tccattcatt tatcagtcaa
    11521 cagcatggtc aatccgcaaa aatacgaatc gattgcacaa tatttgaaac agacagctta
    11581 agggaggaaa acagcatgca aagtttgcca ttcgacatga tcgagctcaa tcgatctttt
    11641 aaaaccaaag aagaagcgat ccgctattgc ggtcagatgc ttgtagaagc agggtgcgtt
    11701 gatgaggaat atatcgatgc catggtagat agagacaaaa tgttatctgt ttatatgggg
    11761 aattttatcg cgattcctca tggaacagat gaagcaaaaa aatatgtgaa aaaatccggc
    11821 atctgtgtcg ttcaagtacc agatggtgta gattttggta ccgaagaaga agaaaagatt
    11881 gcgactgttt tgttcggtat tgcaggagtc ggagatgagc atttgcaact tgtacagcaa
    11941 atcgcacttt attgcagtga tatggacaat gttgtccagc tagcagacgc gctcagcaaa
    12001 gaagaagtaa cggaaaatct agcaattgct taaggagaga gaaaaatgag agcagtacat
    12061 tttggtgcag gaaatatcgg tcgaggattt attggagagg ttttggcagc taatggattt
    12121 gagattactt tcgtagatgt gaatcacacg atcattgatg ctttaaatga aagaaaagaa
    12181 tacgaaatcg aattagcaga tgaatcaaaa gaaaaaatca ctgtaaaaaa tgtcaaagga
    12241 atcaacaatc aaacaaatcc agaaaaagta atccaagaaa tcgctgaagc agatttagtt
    12301 actaccgcca ttggcccgaa tatcttacct tttattgctg agttgattgc aaaaggtatc
    12361 caagaaagag aaaaggaagg aagcacaaca tctttagata tcattgcctg tgaaaatatg
    12421 attggcggtt cagcatttct agaaaaagaa gtgtataaat atcttccgga aacatcattt
    12481 actgacaaat atatcggctt tccaaatgca gcagtcgatc gaatcgtccc attacaacac
    12541 catgaagatc ctttattcgt ccaagtggaa cctttcaaag aatgggtcat tgacgatagc
    12601 caaagaaaaa ataaaaaaat ccaattaaaa ggggttttat atgtagatga tctagaacca
    12661 tatatcgaac gcaaactatt tagtgtcaat actggtcatg cgactgtcgc ttatacaggt
    12721 gccttgttag gttaccagac cattgatgaa gcaatgcaag atgcgttagt tgtggcacaa
    12781 ttaaaatcag ttttgcagga aacaggaagt ttgctgattg ccaaatgggg gtttgatgca
    12841 gagcagcatc atgcgtatat tgaaaaaatc attcatcgct tccaaaacaa aaatatctct
    12901 gatgcgatca cacgtgtcgc tcggacacca ttacgtaagt taggttatca agaaagattt
    12961 acacgtccag tgagagaact acaagaacat aacttgactt gcccacattt gacggcaaca
    13021 atggggatta tttttaatta ctatgatcct gaagatgaac aaagccgtca attgcatgaa
    13081 atgaagatcc atgaaaactt ggaacaattg attcaagaag tcacaggaat caatgatccg
    13141 aaaacaatcg ggaatatcaa gcaaaacgtg aaccgttatg ccaagcaagt cgcttaaaat
    13201 aggatacgaa aaaggggaat gtgacgaaat ttttgtcaca ttcccctttt tcgaataact
    13261 aggctgtttg tccttcaaga tagggcagat ccaattcttt accgtaacgt tgttctaaag
    13321 ctaggcggat caaacgagct gccaggttct catttcttgc aaggataggt ccatggaaat
    13381 aagaaccgaa gacatttcgg taaatgacac cttcagattg gtcttcacca ttatttcctt
    13441 gaccttgtac cactttcccc aaaggtcgtt caccttcacc taagaaagtc cgaccattgt
    13501 ggttttcaaa tccataataa gtttcattga attcttcgtt atggataacg atatcaccga
    13561 taaaccggtt attttcctga cttaacgtgt agtgatccag tgcactgatt ccttggatct
    13621 tttctccatt agctcccatg tagtagtgac ctagcaattg gtagccacca caaatggcta
    13681 acatgacgcc atcattttcg atatagttga tcaaagaatc tttctttttc tggatgtctt
    13741 ttgaaatgat taattgctca aagtcttgac caccgccaaa gaaaaccaag tcatatttat
    13801 cagcatcaaa aggttcatgt atactaacga tctccgtatg gcaagaaacc cccatttttt
    13861 ctgctatata tttcaacatc aaaaggtttc cgttatcacc atatgtgttc atcaaatttc
    13921 cataaaggtg ggcgatattg agttcataat tagccacggt tcattcctcc tttgataaat
    13981 ccttgagcag ctagttcttt acgaagctgc aatacagcag tgtaagtagc taaaatatag
    14041 acatgctcag ttggcaattc tttgattttt tcgattactt ctggtaattc ttttgtttct
    14101 gtcaatttat tttctggaat cccggcaact tttagacgta aagtcatatc tgtatgacgg
    14161 tctcctccag aaataacagc tgggatatcc atatcggcaa agttttcaaa attaccatcc
    14221 caaatccagc tgacatcgat tccgtctgcg taattggcat ttaataaagc cactaaagaa
    14281 aatggataag gagctagacc aatcatatcg attacttgat tgatacctac aggatttttg
    14341 acaagtacta atgtacattt tttcccattg atattgatga cttcttgtcg gccgaatact
    14401 ttctcgtcat atcctaaacc ttgtttgatt ttatcaggat cgacattgaa gtactctgcc
    14461 actgcagtag ctgctaaagc attgtagaca ttatacatac cgccaacttc gattccgtat
    14521 tcatgaccat cgatcacgaa atctgctgac acattgtcca tccgtaccat atcagttaat
    14581 cgataatcca attcaggacg tttgaagtca caatttggac agtaatattt ccctaagttt
    14641 gcataagtga tcattttata atgcaagatg tgatgacaat ttggacataa gacaccgtct
    14701 gtattgtaat gagccatttg ttcacgatct tcttcatggt caaagccata atattttcta
    14761 ggattgactg tttcgataga attgaagatt ggtgaatcac cgttactgat aatcgttgca
    14821 tttggtgact ttgcggcacc gtctacaatc attttatagg tcgtatagat ttctccatac
    14881 cgatccattt gatcacggaa aatatttgta aataagaaca gttctggttt catatattct
    14941 gtgactttgc tcaaacttgc ttcatctatt tctaggacag caaacttttt ctgtcctttt
    15001 tttggttttg cctgcaagaa agtcgataca attccctgta ccatattcgc accagtaggg
    15061 ttggttagaa cttcatcgaa ttgctggcgc aaaatattga ctgttaaagc ggtagtcaat
    15121 gttttaccgt ttgttccggt gacaacgacg acttggtagt cttttgccaa actatctagt
    15181 atatgtggat cgactttcag cgctagttta cctggtaaac ttgatccgcc tttaaaaaaa
    15241 gtttttaatg cccattgcga cgtttttcca actgcaatcg caaaatgact gcgtattccc
    15301 attatgtaac ctccaaaaac gatttgctga cgaataaatt caactaatca taccatatgt
    15361 tgaaaaaaag gttaaattgc ttttcttatt cttaagaaaa ggttacggct gaaagtgcat
    15421 gaaatcggac aaaatcgcat gatttaacaa aaaaacagct tgaaacaaaa tgattgtttc
    15481 aagctgctgt gattttatta ttccctctta cctatattcc cattttaacc gataataatt
    15541 ttctcgcttg gatattcata gcctagatct cgtgtttctt ttggcacgaa taacatcaat
    15601 gtatatagca ttccgatccg cccaataaac atcagtgtag caatcgtgat tttgcccaca
    15661 acagacaagt ctccggtaat ccctaaagat aaaccagttg ttccaaacgc agaagttact
    15721 tcgatgatga tcgagatcag cgtttgttct tctgtagcag ataaaaaaac gatacaaaag
    15781 aaacacatac caagagaaag cataaagaca acgactgatt ttcgcacatc atcttgatcg
    15841 attctccgtc caaaaatatt gatgttatct tcacttttga ggaaggaata tagatacaaa
    15901 ccgatgattg ctacagtagt tgttcgaatc ccgccgccta cagaactagg actgcatccg
    15961 ataaacatca gtaaagaaaa aatgatcagt gttgtgattt gaaaatcacc caaatcgtga
    16021 atctgcagac cagcattacg agtcgtaatc gaataaaaca tcgaattgat ccatttgaca
    16081 ctcatattgg aatcttggaa taaatggtcc ttttccaata gataaatcaa gacagttccc
    16141 gaaacaaaca agataacaaa agctaacaca gctaatttgg taaacaagga aaaacgaaac
    16201 ggaagcttcg cattggaacg tttgtataat agccattccc ggcactccat caatacagga
    16261 aaaccaattc ctccgacaaa aatcaaaaac atgatcagga tcaagaaaaa atagtcatgt
    16321 gcaaagggct tgatggaatc cccagtgacg tcaaacccag agttcgtgac agccgatatc
    16381 gcctgataaa aaccgtaaaa aacggcatca cgccaacgat caaaatagcc tctgtaataa
    16441 aaataaatag aaaagaatgt cccaaaaagt aattgaaacc agattaaaat agcaaaagtg
    16501 atccgaatca gtcggacgat accagacaaa cgcggttgat tcatatccgt catgatcagc
    16561 tgtcgctgtt tcagtgtgat ccgtcgttta gaaaaaatga caaaagcagt agaaatcatc
    16621 atgatcccca aaccaccaac ttgaaataat atttccagca gtataatacc gttatcattg
    16681 aacacagaat tgatatcaaa agtcgatagt ccagtcacac tcactgtact gattgccatg
    16741 aacagcatgt ccacaaaaga aacatggcta tctggttcgc gaaaaatcgg catataaaat
    16801 agaacgagtg ataagaccgt catcaatata taataaaaaa cgatgatttg gatcgatgag
    16861 aaatgattgg cagcaaactt ctgtcctcgc cgctgcagcc ttcgaaagaa taaatcaaca
    16921 tgcacagtac tatcctcctg acaatagtcg tttctaccag tatacaaggg gaattaggaa
    16981 tactcaaaga aattatcaaa cagataacaa tacagctttc gattaaaata gaaatggctt
    17041 ataataagga aaatcctaga aaaaagaagg aggaggaata acaaattgat taatgctcaa
    17101 caaatcgtag aaaaaatgaa aaatcaaaaa ataaattatg atacagttct gaaaaaaatg
    17161 atcatgcaat gggagaaaga agaagtaaag cctaagatat taatacatac atgctgtgct
    17221 ccttgcagta cgcacacatt ggaattcatg tctcaatatg cagagatcac gttatttttt
    17281 tcaaattcga atattcatcc taaaagtgag tatttgcgaa gattacatga acaaaaacga
    17341 tttgtagacc aatttaatga gaaaactgac catcatgttg cgctaatcgt tgatgaatac
    17401 cgtccaaatg aattcaccaa aatggtttta acaaaccatc ttgaaaacga aaaagaaggt
    17461 ggtgctcgct gcagtgcatg cttcaatatg cgattagatc ttgttgcgca aaaagcgcaa
    17521 gaactaggat acgattactt tggaagtgcc ctgaccatct cgccaaagaa aaatgcagct
    17581 ttgatcaatc agatcggaat ggatatccaa aagatttacg ggacacaata cttgccaagt
    17641 gatttcaaga aaaacaaagg ctatgaacgc tctttgcaaa tgtgcaaaga gtatgatatt
    17701 tatcgccaat gttattgtgg ttgcgtgttc gctgccaagc agcaaggatg cgatctgaaa
    17761 gaaatcaatc gggaagcaaa agcttactta aaaacatcaa ccgtagtttt tgaggaaaat
    17821 taaagaaatc tttcggaaaa acgtaagaaa aaaataaaga atttatggta gaaataaggt
    17881 agactgtata atttgtccgt agtaaagtaa ggaaacaaga ataaatttca atgaaggaag
    17941 agataagatg cgaaaagtag cacctatttt gaagccaatc gctgtattaa caatctcgac
    18001 gattgtcgcg actactacag gtattgtgaa tagttccagc taccgtgcac caagttcaag
    18061 ttctagtact gtagaagaaa caacaccaac tacttcagtc tcgacatctg aaccaacaac
    18121 aacggaaagt ttgaatgaaa ccactacgac aagtacatgg gacgatacaa caactagttc
    18181 gtcgtatgat gagacatata caactgacag ctcaagcgaa acaagtaata cggtaccaga
    18241 tggcactcca tcggattcaa ccaatccaag tacaagtccg gatacaagtg ctagctccga
    18301 aacgatacca agcagtacga ctgtagatga taacacgcaa aatgatgatg cagcacgtac
    18361 agcacagcaa aaccaagatt caggaaatac ccaaacgtat aaccagcaag caggtgattc
    18421 tcaatgacat ttttactaga ccttatcaac ggggtgcata aattccttgg ctatttagac
    18481 atcagtccta aatatcttaa ccgtggatat acgattttaa gtgtgattcc cacgctttat
    18541 ttattgagaa ttgtttatgg actttggcaa aaccaaaact atcttcaatt tttcttatat
    18601 ggacttgcat ttctagtgct tgtttatttt actgttttaa atgtatttta ttacttttta
    18661 gataaaaaca cgaaagccga tgtcactcag ctttttgtga agtatttacc tgatgaagcg
    18721 ttcaacatcc agacagaaga atcgatagat aatggaaatt cgatcgataa agtgaataca
    18781 caagaggtca tggtttctta tgacgaagat tatcaattga aattagccga gaatatgcgg
    18841 tatttgattg gaaatggtga gatcaaaaca aatgaactcg gtcgcatgga tggatttctg
    18901 gtcgatagaa atacattgta tccttattac tatgtcaaga aaacaggaga gaaagagtat
    18961 gttctaaata ttggacgaag ctactcggac atggaaaaag tagggaccat tcgacttgac
    19021 tcaacagaag acacattgga acctgtcgga ttgttcatcg tcggcggtga ttttgtcaaa
    19081 gacgggttac gctatcatga gccttatcgt ctgaaattga ttgcaaaaaa ggcacagtcg
    19141 caggaagaac cagtggttta tagtcgtagc caaagaagaa gacattcata atgtgatgaa
    19201 acgccgtgta tcagtggttg cgataaaaac gtttattcgg aataaggggg atgtgacacg
    19261 tcttttgtca cgttcctttt ttatataacg agaaagataa gacgaacaca tcacttattc
    19321 tttcctttca tttataaaca ttgtagaata aagaaagtac aacgaagtat tgtgaaaaaa
    19381 cgtaataaat aacgaggaaa atacaagtag gaggtaagct gtgaaagaat ttttgaaaaa
    19441 ttgggggatt ttgatccttg tattagcggc tattttatta gctagagtgt acgtgtttac
    19501 accagttact gtaaacgggc attcgatgga ccctacatta agtgatggac aacgattgat
    19561 ttcatctaag atctcaaact atgaacgaat ggatattatt actacaaagg aaccggggga
    19621 tgaagaacgg atgattgtta aacggatcat cggtatgcct ggagatacag tcaagatgga
    19681 aaatgaccag ttgaccatta atggcaaaaa gtatgatgaa ccttatctgg atgagttcaa
    19741 aaaagaattt tcagaagata agttacaagg agaatatgct tatagctcag gattccaagc
    19801 acaagcagaa agttcatcca cctttacgag tgactttgaa tatactgtgc caaaaggaaa
    19861 gtatcttgtt ctaggcgata accgcttgat ttcaaaagac agccgaatgt ttgggttagt
    19921 cgacaaagat atgatccaag gaaaagttgt tttccgttat tggcctcttt cagaaattaa
    19981 aatcatgtga tgaaaaaata aaaagaagct gtgacatgtt ttttgtcaca gcttcttttt
    20041 ccgaaaattc cttcttattt cttggagttg ctcacttttt ttgcaatctc attttaagct
    20101 ttttggctga tggataagaa aagcgaagcg tttttgttca taaatagctt ttccccacga
    20161 tggaaggtat gactagtagc agagacaaag cccgtttttt ccaatcgatt attcaattct
    20221 tcttggctaa agccattatg gactttcgga tgactaattt gttcattctt gtcaaagtct
    20281 acgatgatca attgaccgcc aggagctaaa atttcataaa gttttgtaag aatattctcc
    20341 gtatcaggaa tgtgtaaaag tacaagtgat agaaggatga gattagcttg gacagcagga
    20401 aattcgacag aagcatcagc gtggatcgtt cggacatttt tcagatctgc tgcttggatc
    20461 ttttcttctg ccattttcag catagtttct gaagcatcgg caatgatcag ttctttgaat
    20521 ctttccgcaa gcggtaaact aacaagccca gttccgcctc cgtaatccag caggactttt
    20581 tggtggctgt cgcgcggtag ataagtagtt agttcttcgc gaataatctt ggctaatgct
    20641 tgacggtcag gggaatcata atggttagcg atggaatcaa aaatattttt tgtcatcaaa
    20701 tagctcctta cgtaaaactt tgaaatttta acttattata gcacgtgaaa agaaagaaag
    20761 catgctatac tcaattcaaa aagggagaat ctagaaagaa tatgccgata tcgtttgtaa
    20821 aagatagaga ggaaaaagga aagtgtgtcc gagaaatatt actagacttg cctgagtggt
    20881 ttgggcttcc tgaatcaacg gaaaaatata tcgaggaatc aagtaaacta cctttatggt
    20941 gtgaaaaaag aaaagaagaa tatttaggct ttatcactct ttcacagaca agtgaagata
    21001 ctgccgaaat ctattctatt gtatgggaat aaaaaaagac tatcatcacc aaggattagg
    21061 aacaaaactt tttaaagaag cagaaggtta cgcagcaaaa cattacaaat atttgcaagt
    21121 gaagactgta gacgaggggc actactctat atatgatcaa actatttgtt tctacgaatc
    21181 attaggattt tcaaggttgg aagtttttcc aaatttatgg gatgaatgga acccatgttt
    21241 agttcttgtc aaaaaattgg aacaaaagtg agcaatagat ttaatactaa tctgtgcttg
    21301 atgaaaattc tcactgtaaa aaatgctgaa aatcaagtat aataccatag gaacaaactg
    21361 gaaggtgaaa aagagcatgg cacaactatt ttttaagtat ggcgcaatga atagcggcaa
    21421 gacgatcgag atcctaaaag tcgcacataa ttatgaagaa caaaataagc cagttgtctt
    21481 aatgacaagc ggtattgata caagagatgg tttaggcgtt gtttcaagcc gaatcggact
    21541 gaaacgtaat gcgatgccga tatttgaaga aacagacgta tttgacgtaa ttcagaaaat
    21601 ggaaagcaaa ccctattgtg tgctgatcga tgaagcgcaa ttcttaaaaa agaaacatgt
    21661 cattgctttt acgagaattg tggacgaatt ggatattccg gttatggcat ttggtttgaa
    21721 aaatgatttt cgaaacgagt tatttgaagg atcaaaatat ttattgcttt atgcagacaa
    21781 aatcgaagaa atgaaaacaa tctgttggtt ctgccacaaa aaagcaatca tgaatttaca
    21841 ttatattgat ggaaaccctg tttatgaagg cgatcaagtg caaattggcg gaaatgaagc
    21901 ttattacccc gtttgtcgaa aacattactt tcacccatca atgattacag aaggagaata
    21961 agcatgtacg atcaattaca agcaattgaa gaccgttatg aagagcttgg agaactttta
    22021 agtgacccag aagtgatttc tgatacaaag cgttttatgc agctttcaaa agaagaagca
    22081 aacacgcgcg aaacagtcga agtttatcgt cgttataaag aagtagtaca aggaatcacc
    22141 gatacagaag aactgcttgg tgaaaaactg gatgatgaaa tggctgaact agcaaaagaa
    22201 gaattatctg aattaaaaaa agaaaaagaa gtcttagaag aaaaaatcaa gatcttgctt
    22261 ttaccaaaag atccaaatga cgataaaaat atcatcatgg aaatccgtgg agcagcaggc
    22321 ggagacgaag cagcattatt cgctggcgat cttttcaata tgtaccaaaa gtatgctgaa
    22381 gcacaaggct ggaaaacaga agtgatggaa gctaacgtta ccggaatcgg tggatataaa
    22441 gaagtgatca tgatgatcac cggagacaac gtatattcga aattaaaata tgaaagtggt
    22501 gcgcaccgcg tccagcgtgt tccttcaact gaatcgcaag ggcgtatcca tacttccacc
    22561 gcaacagttg tcgtgatgcc agaagctgaa gaagtagaga tcgatattga agacaaagat
    22621 atccgtacag atatctatca tgcttcaggt gctggcggac agcacgtcaa taaaacagca
    22681 tctgctgtac gtttgactca cttaccaaca gggatcgttg ttgctatgca agatgaacgt
    22741 tctcaaatca agaaccgtga aaaagcaatg aaaatcttgc gtgctcgtgt gtacgataag
    22801 atccagcaag aagcacaaag cgagtatgat gccaatcgaa aatcagcagt cggaactggg
    22861 gatcgttcag aacggatccg gacgtataat ttcccgcaaa atcgtgtgac tgatcatcgt
    22921 atcggattaa ctatccaaaa attagatcag attttagcag ggaaattaga tgagatcgtt
    22981 gatgcattga tcatgtatga tcaaacatca aaactggaag ctatgcaaaa tgggtaaaat
    23041 gacctatcga gaagtcctgt cacgggcttc ttctttttta gaggatcatg ggaaagaagc
    23101 atatagtatc caatttttat ttttggaacg aaaacaatgg aaaaaacttg attggctcct
    23161 tcatatgaac gaagagattt cagaagaaga acagcggttg atcgaaaccg atctgcgact
    23221 tctgcttgca gatcatccac ctcagtattt gctaggatat gcagattttt atgatcatcg
    23281 gttaaaggta actgaagcaa cactgatccc tcgaccagaa acagaggagt tagtcgaatg
    23341 gtgtttagac gagacgcctg gtgtaccgtt agaagtgata gatattggga cagggactgg
    23401 agcaattgct attagtttga aagcagcaag aaaaaattgg catatatctg ctgtggatct
    23461 ttcagaagaa gcattagaag tagcgaaaga aaatgctcag aaagaaggaa cgaaaatcag
    23521 tttttatcat ggagatacat taggaccagt aatggatcag caatttgatg tgattatttc
    23581 taatccgccg tacatcagtc ggaatgaatg ggaactgatg gatgaaagtg tccggtcatt
    23641 cgaacctaaa atggcccttt ttgctgagaa cgatggatta gctatttatg aaaaaatagc
    23701 agttgaagca ccaagcgtac taaaatcaaa tggaaagatt tttttagaaa tcggatttcg
    23761 ccaaggtgaa gcagtaaaaa aaatatttca gcaagcattt ccagataaaa aagtggcgat
    23821 aaaaaaggat ctttttggca atgaacgaat gatccaagtt tatggttgaa gttgtggatg
    23881 aaaaattttt tatttgtttt tttattataa aaaaacactt atttgacaag gatgtaaacg
    23941 actttttggt ttatcaacaa gtttatccac tattgacaaa tagattatcc acaaacagtg
    24001 gaaaacttga ggataaactc agacaaaata agaatgtatg aaaaaggggt tgtggataaa
    24061 ctgtggaaac gaaacgatat gatgaaacag aattgcaaga ggcagccgaa gcactgaaag
    24121 aaggagaact tgttgctttt cctaccgaaa cagtatacgg attgggcgcc aacgctcttt
    24181 taccaaacgc tgtcaagaaa gtgttttctg taaaagggag accgcaagat aatccattaa
    24241 tcgtccatgt cgcctctttt gaacaagtaa aagagtatgt ggacaacttt catccggcag
    24301 cagagaagat tgtgaagaac ttctggcctg gaccattaac tttgatattt aagatcaaaa
    24361 aagacacttt gccctcagtt gtgacgggag gattatccac agctgcattt cgtataccgg
    24421 ataacaaaaa aacactagaa gtaatcgaac tttccggtgt tccgcttgtc ggtccaagtg
    24481 caaatacgtc gggaaaacca agtccaacga ctgcagatca tgtatatcat gatctacaag
    24541 gaaaaattac cgggattatt gatgatggag ctacgcgaat tggtgtagaa tccactgttc
    24601 ttgatttaag tgatccaaca gccatgccta tgattttacg accaggtgca gtaacgaaag
    24661 aacaaatcga agcagtcatc gaatctcctg ttgctattga tcagcatctt gtaaaagaaa
    24721 atgaaacacc aaaagcccct gggatgaaat acaaacacta ctcacccgat acacgtgttc
    24781 tgatggtcag agatggcgat tggtcaactg cagttcaatg ggcaaaaaat aagaagatcc
    24841 gtgcaggtgt catagcaagc cccgaaattg cggatcaagt gcggacagat actgcagctg
    24901 tttatatgta taacgacaac tcagtagaag cggcggctaa aggattgttt gcaggtctaa
    24961 gaggattaga tgaaccaaca cttggattag atttgatttt tgtacaagtg tatccagaaa
    25021 ctggattggg gaatgcttac atgaatcgct tgaaaaaagc agcaggacaa aattattttg
    25081 aaaaatgatc aattggttat tgtcgcattc ttttagtatg atacaatgct atcaagtaaa
    25141 tcttctatca gtgaacgaaa aactaagcgt aactaatcgt aatagaagag atacgaatat
    25201 ttggcaattt gtttttgatg ggaaaaataa aattgtagga aaataaaaag gagctgttgt
    25261 ttgtggtaga ttacaaaacg tttgaccctg atctttgggc tgcgatcgcc aaagaagaag
    25321 aaagacaaga acataatttg gagctgattg cctctgaaaa ctttgtctcc gaagcagtga
    25381 tggctgcaca aggaagtatc ttgacaaata aatacgcaga aggttatcca gggcatcgct
    25441 attatggtgg gtgtgaattt gtcgatatcg ttgaaaattt agcgattgac cgtgcaaaag
    25501 aattattcgg agcgaaattt gcgaacgtcc agcctcactc cggctctcaa gccaacacgg
    25561 ctgcttatct cgctttggta gaaccagggg acacgatctt aggaatggat ctttccgcag
    25621 gcggacatct aacacatgga tcaccagtca acttcagtgg caaaacctat cactttgttg
    25681 cttacggtgt tgatccgaca acagaagtta ttgattataa tgtggtacgt attttagcta
    25741 gaaaacatca accaaaattg atcgtagcag gtgccagtgc ttacggacga acgatcgact
    25801 ttgcgaaatt cagagaaatc gcagatgaag taggcgcaaa actgatggta gatatggcac
    25861 atatcgcagg attagtagca gcaggacttc atcctaatcc agttccttat gcagatatca
    25921 caacgactac cactcataaa acattgcgtg gccctcgagg cggcatgatt ttgacaaacg
    25981 atgaagcatt agcaaaaaaa ataaatagtg cggtatttcc tggtattcaa ggcggccctc
    26041 tagagcatgt gattgcgggt aaagcagtag cattcaaaga agcattagat cctgcattta
    26101 aagaatatag tgaacaaatc atcgccaatg caaaagcaat ggtcaaagtt ttcaatcaag
    26161 caattggaac cagagtcatt tcaggggcga cagataatca tctgatgttg atcgatgttc
    26221 gcgagttagg tataaatgga aaagaagcag agagcatttt ggacagtgtg aatatcactg
    26281 taaataaaaa ctcgattcct tttgaaacac taagtccatt caaaacaagc ggtattcgaa
    26341 tcggcacgcc agcaatcact actcgcgggt tcaaagaaga agatgctgta aaagtggctg
    26401 aactagttgt caaagcatta caagcaaaag atgataacgc tcaactagac gaagtcaaaa
    26461 caggtgtacg cgaattaact gaaaaatttc cgttgcataa aaaataaaaa tttaaattcc
    26521 attagtaaac agaaaagttc aatgttgggc ttttctgttt attttttggg aaaacggatt
    26581 ctttgacaat atcggtgatg ctctctagta tatgaggtgt aattttagtc ttcacactaa
    26641 atctcaggga ggaaaagtca tgactgatcg tatctcgtta gaaaaggaag cagtagcatt
    26701 cagtgatgca aatgcgcctc atccgcgtat ctatgaacta gcaccggaag aaggaagagt
    26761 tttactagaa gaagtacaag aatcacctgt gaacaaatat tccgtcgata ttgaagactt
    26821 gatggtggat actggcgaat ggggaaaact caatattcgt ctcgtacgac cagaagggaa
    26881 tatggataaa ttaccagtta ttttttatat tcatggagca ggctgggttt ttggcagtgc
    26941 tcaaacccat gataaattga tcagagaact tgcggttcgt acgaattccg tcgttgtctt
    27001 tccagaatat agtcgatcac cagaagcaaa atatccaaca gcaattgaac aaaattatgc
    27061 tgtgttgcaa cagctgaata aattagccaa gtcaaaaaat ctggatctcg agaatctaat
    27121 cgttgcagga gattcagtag gtggtaacat ggctacagtc atgacgatct taacaaaaga
    27181 acgaaagggc ctcccaatat ccaagcaatt gctgtattat ccagtcacaa acgctgattt
    27241 tgatacagat tcctatcatg aattcggaga aaactatttt ttgacaagag aaggaatgat
    27301 gtggttttgg gaccaatata cgacgaatga agaagagcgt gctgaaatca cagcttcgcc
    27361 tttgagagca aatataaatg aactaaatga tcttccttca gcaatgattt taacgggaga
    27421 agcggatgta ttaagagatg aaggtgaggc ttatgcgcgc aaacttcgtg atgcaggggt
    27481 tcctgttaca caagtacgct tccaaggaat catccatgat tttgtcatgg taaatgctat
    27541 ggatcagaca aaggcaacgc gtgcagcaat ggcattatct acttcttgga tcaagaaaaa
    27601 agaataagct ttgcttgtcc gcaggaaaac ttcttttcaa aaacggattt tcttaggaaa
    27661 aatggcgagt ttgactagtc aatcacttga ttttgtttta caattaaaaa gaaacgacag
    27721 aacaaaggag agcttaaaaa atgggcaaat ttcaagtgat cgatcatcca ttgattcaac
    27781 acaaactaac tattattcgg gacaaaaact gcggaacaaa ggtttttcgt gaagtagtcg
    27841 atgaaatcgc tatgttgatg gcatatgaag tatcacggga tatgccattg gaagacatcg
    27901 tgatcgaaac accgatcact gaaacaacac aaaaaacgtt gtctggtaaa aaagtagcga
    27961 ttattccaat cttgcgcgca ggtattggaa tggttgacgg tatcttggaa ttgattccag
    28021 ctgctaaagt gggacatatc ggtctttatc gagatgaaga aacattggaa ccacatgaat
    28081 atttcgtcaa acttccagaa gacattgatg cacgtcagtt gtttgtagta gatccaatgt
    28141 tggcaacagg cggatcagca atcatggcaa tcgatgcatt gaaagaacgt ggcgcgtcga
    28201 acattaaatt tgtttgtttg gtagcagcac ctgagggagt aaaagctttg caagaagcgc
    28261 atcctgatat tgacatctat acagcttctc tagatgaaaa attgaatgaa catggttata
    28321 tcgttcctgg actaggggat gcgggtgacc gtttgtttgg tacaaaataa gtaaatacga
    28381 aaaagggtgt gacacaactt ttgtcacatc cttttttggt catttttaac gtttgatgca
    28441 gaacagcttt ttcacagctt tcgtttgcat ataaaaaaac catcccaaaa atgcagagat
    28501 ggtcaaattc aaatcttttt tagttctttg tagttaacga ttactacacc cttactttgc
    28561 gtcatcaagt tcgcattttc tgcagtttca tcaatctcaa caacagcgga atttttcaat
    28621 tgctttgaaa tcgttccagt ttgcgacttg ccgtgaattg tgaacattac gtgagtattg
    28681 atcttgaatt tttcaccaat ttccgatggt acgatagttg tatcaaattt tccaaaagtt
    28741 gccattttca taaaacctgc ctttcacatc aattatacca cgttttatga aaaatatcat
    28801 gaaattaaac taattttcca tcggactctt tacaatcagc caaatagagt atataatttc
    28861 ttttggataa ggccagctta gctcagttgg tagagcaacg cactcgtaac gcgtaggtcg
    28921 taggttcgat ccctatagct ggcattaaaa gagaagacag atatatcaag gatttttaat
    28981 ccattgatac atctgtcttt ttgtttaaag gaaataaagt atgctttctt agcaatagag
    29041 catgtattat ttctataaaa atttaggaga ataaaacgac tagcaatata gctgtgaaat
    29101 caaatatcac atgaactgcc caacttgtaa tgatcgagtt gcttttaatg gcagcttggt
    29161 tgaataacaa tcttgccacc ccttgtatca aaaggatgtg tgctacagtg tgtaaaatat
    29221 ttccattatc ataagtactg taatggataa atccaaagat gattgctgac aagaaactag
    29281 cgacaggaat gctgaactta ctagaaaaaa tagcgagaaa atacactgag aacaattctt
    29341 ctccaagtat catgataggc aaaataataa ataataacgg gctgaaagcc tcatttattg
    29401 gattgcctgt taaaccccat ttcaaaattt gttgcaaaaa taccgagact gcggcactga
    29461 ttactacatt gataaaaaaa tatttggcta tatttttgac aggagcgaca ggtttcgaga
    29521 acattttttt cgtatctttt ttaccaaaaa caagtgtaaa tgctataaat ccagtgatag
    29581 ttaaagaaaa aatgctaata atggatggcg caaatagcaa ccctaacaaa ccgagtacaa
    29641 cgacaatagt gcccaatatc ccttttttaa gttctatttt ttttcctaaa atgttattca
    29701 tgataataac tcctactatt cagtttttga agatagagtc agtatacatg aagagttaaa
    29761 ataggcaatg tttttttatg gatatttgta ttgctaaaaa tttatcttat atattcattt
    29821 tgattatact acttttattt gtaaaaattt tctagcaaaa ccaagtgctt gcaactgatt
    29881 aagcgtacaa ttttttagat gttccgagcg tacttcaatc atttcaaagg agttgctact
    29941 taaatcgata ttttttaaat cagtatcaaa aaagctagca ttttctaaat cattagtaga
    30001 aaacattatt ttagtgaggg aacagtctac aaaatctgcg cttgataaga cagagtgctc
    30061 aaaggtactt tcttttatgt ttgaaccaga taaatttaca tagtccattt tacaattctc
    30121 gaataacgtg ttcccaatat aactttccat caatttagta cctgttaatt tacaattgac
    30181 aaatttcacg cgatgcaaca tgctttttgt caatatacag cctgaaaaat cacagttttc
    30241 gaatatacag tcggtaatct ccattctttg aaaatcattg gaagcaaaaa atgcatactt
    30301 gaaaatagat ttgtaaataa ttggatggca gattatttgg ttttcgatga cctctttttg
    30361 tgaaaggata ttatacagtt caaaatcttc gttttcatag atatgaaaaa aggatccttt
    30421 attcaagctt gcttcattaa ctttaggaaa aatcatattt aattacctcc attttcataa
    30481 agtcatatta acaaaagcta aaccaactta cattagcaga aaatgagata ggttttcgcc
    30541 tttttcgata acgatagtgt cgctatctct tgaaacgttc ttagaattgc cctgagagac
    30601 acaaattagg cgtaattcta ataaaaatct tagaataaaa atttttactg atttaattta
    30661 gaatgttttt aaaataaaaa tcgttgccat aacagtgtat tgaaaggttt taacaatcca
    30721 gtaatgattt aaaaaaatct agatgtagcg tatactttgt ttatagaatg tagtgggaag
    30781 aaatatattt ttgggaggaa atcgtgatgt ctaaaagtga agaaatagaa aacatggtac
    30841 taaaattata tgatctcgtt ttaaatccag agatcaaaga aaaggaacgt atacttttga
    30901 tagacgcaaa gacaggctta gaaaaaggtc agtattatcc taaagtcata aataatttgg
    30961 aacgtagttt acgtccgtta gcaatcaggg gagaattgtc taaaccagta tcaccgtttt
    31021 atatggagat atcaacaata ggaaaatttg aaaaagaatt aggtcgagga atggcttcgg
    31081 caccgattac ttttgggcat ttataaaaac gagttattca tctcaatgaa ttaaaaagta
    31141 tagtcaatct cataatgcag gctaggttca tttatttgaa cagagtctgt atttttttat
    31201 tctaaataaa gaaacagatg tttctttata ttgtatttta tcctttaatt aacacaaaaa
    31261 cagctagtat
//
LOCUS       DADQCX010000026        31024 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.026, whole genome shotgun sequence.
ACCESSION   DADQCX010000026 DADQCX010000000
VERSION     DADQCX010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.026"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(533..1087)
                     /locus_tag="J8R83_001118"
     CDS             complement(533..1087)
                     /locus_tag="J8R83_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAZ9574257.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(1213..3142)
                     /locus_tag="J8R83_001119"
                     /pseudo
     CDS             complement(1213..3142)
                     /locus_tag="J8R83_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(3448..4164)
                     /locus_tag="J8R83_001120"
     CDS             complement(3448..4164)
                     /locus_tag="J8R83_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAZ9574258.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(4165..5988)
                     /gene="glpO"
                     /locus_tag="J8R83_001121"
     CDS             complement(4165..5988)
                     /gene="glpO"
                     /locus_tag="J8R83_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAZ9574259.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(6002..7498)
                     /gene="glpK"
                     /locus_tag="J8R83_001122"
     CDS             complement(6002..7498)
                     /gene="glpK"
                     /locus_tag="J8R83_001122"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAZ9574260.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(7634..9094)
                     /locus_tag="J8R83_001123"
     CDS             complement(7634..9094)
                     /locus_tag="J8R83_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9574261.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(9084..10379)
                     /locus_tag="J8R83_001124"
     CDS             complement(9084..10379)
                     /locus_tag="J8R83_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9574262.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(10711..11388)
                     /locus_tag="J8R83_001125"
     CDS             complement(10711..11388)
                     /locus_tag="J8R83_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAZ9574263.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(11418..12509)
                     /locus_tag="J8R83_001126"
     CDS             complement(11418..12509)
                     /locus_tag="J8R83_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAZ9574264.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(12610..13044)
                     /locus_tag="J8R83_001127"
     CDS             complement(12610..13044)
                     /locus_tag="J8R83_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9574265.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(13628..15085)
                     /gene="ascB"
                     /locus_tag="J8R83_001128"
     CDS             complement(13628..15085)
                     /gene="ascB"
                     /locus_tag="J8R83_001128"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAZ9574266.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(15082..16977)
                     /locus_tag="J8R83_001129"
     CDS             complement(15082..16977)
                     /locus_tag="J8R83_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9574267.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(17035..18810)
                     /locus_tag="J8R83_001130"
     CDS             complement(17035..18810)
                     /locus_tag="J8R83_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9574268.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(18860..20356)
                     /locus_tag="J8R83_001131"
     CDS             complement(18860..20356)
                     /locus_tag="J8R83_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9574269.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(20550..22172)
                     /locus_tag="J8R83_001132"
     CDS             complement(20550..22172)
                     /locus_tag="J8R83_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAZ9574270.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(22500..23813)
                     /locus_tag="J8R83_001133"
     CDS             complement(22500..23813)
                     /locus_tag="J8R83_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAZ9574271.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(24058..24282)
                     /locus_tag="J8R83_001134"
     CDS             complement(24058..24282)
                     /locus_tag="J8R83_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574272.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(24302..24670)
                     /locus_tag="J8R83_001135"
     CDS             complement(24302..24670)
                     /locus_tag="J8R83_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAZ9574273.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(24866..25576)
                     /locus_tag="J8R83_001136"
     CDS             complement(24866..25576)
                     /locus_tag="J8R83_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574274.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(25594..26091)
                     /locus_tag="J8R83_001137"
     CDS             complement(25594..26091)
                     /locus_tag="J8R83_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574275.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(26128..26580)
                     /locus_tag="J8R83_001138"
     CDS             complement(26128..26580)
                     /locus_tag="J8R83_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9574276.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(26715..27320)
                     /locus_tag="J8R83_001139"
     CDS             complement(26715..27320)
                     /locus_tag="J8R83_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAZ9574277.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(27770..28390)
                     /locus_tag="J8R83_001140"
     CDS             complement(27770..28390)
                     /locus_tag="J8R83_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9574278.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(28392..29261)
                     /locus_tag="J8R83_001141"
     CDS             complement(28392..29261)
                     /locus_tag="J8R83_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAZ9574279.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(29284..29691)
                     /locus_tag="J8R83_001142"
     CDS             complement(29284..29691)
                     /locus_tag="J8R83_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAZ9574280.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(29710..30999)
                     /locus_tag="J8R83_001143"
     CDS             complement(29710..30999)
                     /locus_tag="J8R83_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574281.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT         8813 a         6716 c         5138 g        10357 t
ORIGIN      
        1 accgtttaag gaagaggttg tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg
       61 ggaaaatagc tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga
      121 acaccgttta aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt
      181 tgtgaaaatg gatttctaca tttttgcata aatttggctt aataccgaga aactggcttt
      241 tgaataccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagaaac
      301 aaacggaaaa atagctgctc atattttgcc gttttttgag ctaataccga aggtcagctg
      361 attgaacacc gtttaccaag aggttgtgag cctaccattt aactccgaat cacaagaaat
      421 aatttcaaaa acaacttctc ctgtttttgg ttcggttggc ttattatcga gaagtagcta
      481 ctgggagtct atttatcaaa aaaaggaatg cgacataggt cacacccctt ttttattttc
      541 tttgaaacat ctttcggtac tcgacagcat acaagacaaa agattgtaaa agaccgtaag
      601 tgatgacggc aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa
      661 ggatcatgcc aacatagatg acagcagtcg ctactttgcc ataccacttc gctccactta
      721 atttgatatt tttagatagc ccgattaatc cagctacaaa cataaagcct tcttttatca
      781 agaatagacc aaacaacagc caaagccacg gtcgatacca tgccatagac aaaatcagaa
      841 aaagttgtgt caatttatct gcaaacggat caagcacctt ccctaagtct gttacctgat
      901 tatatctccg agcaatgacc ccgtctagat aatcagacaa acctgagaca acaatgaccg
      961 ctcctgctat ataaaatgac tgtctcagca caaaataaag ataaatcggc agcaaaaaaa
     1021 tacggaatat cgataaaaga ttcggaatcg tttgtatttc tttacgccag tctgtgctta
     1081 atttcatttt atcgccctac ctcctcagca ctcttttctt tttattttag cttacacggg
     1141 gaataaaacc aatgatttca ctgtttttat ttttctttac agacactgat attatgagct
     1201 aatttgagat aatcacttgc tgttttcatc gtttactctt ctttcttcct gtcgtttgcg
     1261 catttctttt actagtactt tatgagcttt ttttgatcct cgctctaggt cacgctgccg
     1321 tttacgtgtt ttataatcga taaacagact gtctaaatcg taacctgtcg ggtacagatc
     1381 ttctgctgaa cgcaccagac gaacacgctg acgaggcacg tggattattt ttttgtctaa
     1441 atatacatca atcgtatctt cacctatatc ttcataaact aacgcttctt tttggtattc
     1501 attgacaaat atccgatcac cttttgcaaa gagctgacgt tcttttttat tctccttcct
     1561 atttgtaact gctgtcttag gaagaaattc ttttttctgt gtccgatagg ctttttccgc
     1621 caagtaacgc tctgcttgat ggatcaattt catcgacata tccattttat gagcaatcca
     1681 caaagcttgg ctttctcctg tttcttccaa cccgcaactg atatttagga cgaagtgctt
     1741 cccgatcgaa agccatagca gccggcacaa aatcttcatg atctccggcg aatttcttga
     1801 tttctccata atgggtcgtg gcaatgatca atgccccttg ctcatacata gattccatga
     1861 ttgcgatcgc tagtgcagcc ccttcatttg gctctgttcc actgccaatc tcatctaaaa
     1921 gtaccaacgt attccttttt atctttttca aaatagcagc gatgttttgc atatgaccag
     1981 aaaatgtact caacgcattt tctaaatttt ggtggtcacc gacatcgacg aaaatctcat
     2041 caaagacagc aagctctgtc ccttcttttg ccggaacttg cataccgaac atcgccatca
     2101 aagtcaataa accgactgtc ttcaacacga ctgttttgcc tccggcattt gctccggtga
     2161 taatcaagcc tcgatagtct ttaccgattt caacatccaa tggtaccgca tgctcaggta
     2221 aaaatggatg tctgccttgc ttgataatga tatgttccga tttattgatt ctaggtgtgc
     2281 ttccattgat ttctcggcta aattttgccc gagcaaagat gatatctaac accgtgatcg
     2341 tttcgatcaa taaatcgatc acttcttcgt tttctgcgat agcaccagtc aatgccgcca
     2401 ggacttgata ttcttcactg atttcttcag cttttaacaa ctgatagtgt tcattcaatt
     2461 tagaaatcac agttggttca ataaaaaccg tcgttctttt atttgattca tcgataatcg
     2521 ttccatctat tttattttta tagctggctt tgataggaat cgtatagtat tcgccttttt
     2581 gaacaatcat tgcttcttgg atcatttctt tgtttttcgg atgacgcaag aatttcagta
     2641 attttgactg gatttctttt tcgattagtt gtaattgttt gcgtacttta cgcaaattac
     2701 gtgacgcgtc gtcactgact ttattatttt ttattttctg gtcaatcaac tcttctacat
     2761 ttatcaaatc aggaagatgt ttgctataag caaacaacaa gggtgtctgg tattgattct
     2821 tatcaaaaaa ctttgtgatc atccgactgc ttctaagaaa atccgcatat tcgatcaaat
     2881 cggttggctg cagaatcaac ccttttttga cttgttctgt cagtgcatcg atcctcggca
     2941 accccataaa tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt
     3001 cttgacgatc caagacagtt tgtaggtttg tcgagaccgt catatcgctg attcgttttt
     3061 tgctatagtt tccaattgct cttgcttgga tttccttttt gatccgatca aattgtaatt
     3121 gactaatcat ttcgttgtcc atattctctc cttttcttga agagatacct gtcccaaaat
     3181 aaataagggc ctagagataa ataaaaggat agaacacagc ttaaaaaagt catgtcctat
     3241 ccttattaga atacaaagat attgttttcc tgacaggtac cgtttcataa gcacaccaaa
     3301 taaactttgt ttattggcta ttcgacttac tgattagata ccagctacac tcacaaaaca
     3361 taccccattc ttctaggtct tatttatttt ccacttaact atagcaagac acattttggt
     3421 tgtcaaactt tagtatgttt tatagattta caccattaat gaatagacac ctaccgcgat
     3481 aattgctccg atcattggac ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc
     3541 tttattagct attggcaata ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt
     3601 gattgcatat cctgttggcc ctcctaatga aagaccgatg gctaagatca atccacctac
     3661 agcgaatacg ttcgttccag gtgcaaattc gttttgtcca aaagctagca acccaagaac
     3721 taatacaaat gtaccaatta attctgtgat cacatttgct ggataattcc gtatagcagg
     3781 acctgttgca aacgttccta aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa
     3841 ataagaaagc caaacaagaa tggcccctgc aaaagctcct aaaacttgcg caatgatgaa
     3901 aggaacgaca agattccaac taattgcccc tgtcatcgcc atagctagag agactgcagg
     3961 attcaaatga gctgggccca tgaatccaga aatatagaca gccattgtta cagcgagtcc
     4021 ccaaccaaat gcgatgacaa tccagccaga agcctgtgct ttacttttgt ttaaattcac
     4081 agccgcacac acaccatctc caagcaaaac taggatcagt gtcccaataa actcccccat
     4141 gatttgagtc atatcactgt tcatttattt ctcccccttt agttcccgca gatctgattc
     4201 tgcaatcaat gcttctaaac gtttagtctg ttgcgccttc tcctcttctg tccattcaaa
     4261 atatccagca attgcatcga tcacaggttg cttgatctca tcaagctgat ctcgttcaaa
     4321 caacagatga tttgtacgac gaatgagata atcgcctggg gccaaaacca tttcttcttc
     4381 taaaccataa cgtaaccgag ctgactcagc gagactcaaa ccaggataag gtgccatttc
     4441 ttttgctaat tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga tataagtagc
     4501 atcttcttcc tctaaaccgg ctgctactcc ttcttttgct aattctgtca ctgtttcttc
     4561 taatttagtt ggatcgaagt ttccacctga aatctgatat tttttagagt cgatttcttt
     4621 cgtctctatt ccgtattctt cttttaataa ttggcgtatc aatcgcaaag ctccttctgc
     4681 catcttacgg taatcggtga ttttcccacc agataaagtc agcaaaccat ctggttctct
     4741 ttctaaagaa ctacctctgg aaatcgtaga aggtgctttt tcatcacggc tgttttccaa
     4801 atggttcaac acgtcttcta cttcagcacg agaaactttg ttttccttat attcacttac
     4861 tgtatcgaca actttattga agctcttgtc tgaaatcgat ccattatctc caccattgta
     4921 atcagaacca gaattaccaa tcaacagtgg acgaagtcct gcccagcttg cttcgatatc
     4981 attcaatgtg atatttgctt ctggatagcg atgattgatc acatccaata gataatctac
     5041 atcttcttgt gtgactttcg gatccgtaaa atctccttgg taatccgtat ctgtcgtacc
     5101 aaagtaagtc ttgttttctc ttggaatagc aaaaaccatc cgcccatctt gctttcctgt
     5161 atcgaagtat gtgggttgcg gtacaggcag ttttttcgca tctacaacta aatggatccc
     5221 tttagttgga cgcattttag gagagactgg acgcgtaaaa ttcaagtttc gtactttatc
     5281 tacccaagga ccactcgtat tgatcactaa ttttgctttg atttcgatca cttcatctgt
     5341 cagcaggtca cgagctttga cgccaacgat ttgatcgcca tcatataaaa agccaaccgc
     5401 tttcatttta cttactagat aagccccatc ttcggcagcc tttttgatat tatcaatcac
     5461 taaacgggca tcattgttgc ggaaatctag atagacaccc gcgcctttta gcccttcttt
     5521 tttcaaaaac ggttctcttt ccaatacttc ttctggtgtc agcgtataat tctcatattt
     5581 ggttcctgtc acatttgcca gtttgtcata aaggtccatt gctactttga ccgagaacat
     5641 attgaaggtt gttgctcctt cgccctcata gattggcaaa agcattggat ctggttttgg
     5701 gatgtgtggg gcaatacttt gtacgactgc acgttcacca actgtgtcag ctactacttc
     5761 cacatcaaat gtcttcagat aacgaatacc gccatgaaca agtttggtcg agcgagagga
     5821 agtcccttct gcaaaatcct gcatttcgat caatcctgtt ttgattcctg atgctgctga
     5881 ctggactgcc acaccggcac cagtgattcc gccaccgatg atcaacagat ccaattcttc
     5941 ttgctgcatt ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat ggatttcctc
     6001 cttattcaaa tgcttgggta gcttttactg cttttttcca accgttgtaa agtttttctc
     6061 ggcgctcttc ctccatttga acttcaaata gcttgccagc ttcataaaat tcgcggatct
     6121 cgtctgtatc tttccaataa ccgacagcta atcctgctaa aaatgctgcc cctagcgccg
     6181 ttgtttccaa gttttctgct cgttggatcg gtacattcaa gatatctgtt tggaattgca
     6241 tcagatattc attgtttgct gcaccgccat ctactttcaa tacaggaatc ttgattccag
     6301 tgtcatcttg catcgtatcg atgatatctc tcacttgata agcaatcgac tgtaaagtag
     6361 ctttaatgat atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg
     6421 cctgatccca ataaggagca cctagcccaa cgaatgcagg aacaacataa acctcatctt
     6481 cgcttgtaga gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac atttgaagtc
     6541 catctctcag ccattgaatc gaagaaccag ccacaaaaat acttccttct aaagcatagt
     6601 aaacctttcc atttatgccg taaccaattg tcgtcaataa attatttttg gataattgcg
     6661 gtttttcacc ggtattcatg acaataaatg aacctgtacc ataagtattc ttgaccatgc
     6721 ctggttcgaa tgccatttgt ccgaataatg cggcttgctg gtctcctgcc atccctgaaa
     6781 ttggtgcttc gcttccataa aaatgataac cttgcgtata accataaact tctgagttag
     6841 aagtgacttt tggtaacatc actcgaggaa tatttagtaa atctaaaatc tcctgatccc
     6901 aatctagctg atggatattg aacaacatcg tccgactggc attcgagtaa tcagtaacat
     6961 gtgcttgtcc atcggtcagt ttccatacta accaagaatc gatcgttcca aacatcaatt
     7021 cgcctttttc agctcgttct tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg
     7081 ttgctgagaa ataggcatcg atcactaacc ctgttttttc gtggaaaaat tcttgatagc
     7141 cttcattttt taagttatct gcaattccag ctgactgtct ggattgccaa acaactgcat
     7201 gatagattgg acgtcctgta tctttttccc atattactgt tgtttcacgc tggttcgtta
     7261 tgccaatccc agcaatctga tttggtttga tccctgattc gatgaacgct ccggcaataa
     7321 ctgactgtac agaattccag atttcatttg catcatgttc cacccaactt tcttgcggga
     7381 aatattgcgt gaactctttt tgagaactgc cgatgtgtct tcctttcttg tcaaagataa
     7441 ttgctcgtga gctagttgta ccttggtcaa tcgccatgat atacgttgat tctgtcattg
     7501 tgattccctc cattatatgc aaacgctttc tttaactact cttatcatac tactgtttta
     7561 aaaaaagaaa ctgtcaaaat tttattcttt ttttcttttt ttgacagttt tttattatga
     7621 agctattttt taatcaattc ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa
     7681 taatgtcgta aggtgacgca aattctgaca gataatattc acactgtttt ttgtttctct
     7741 ggcaaaatgt gatcaccaaa tcatattctt taccttcttc ataacttcca atctcaatac
     7801 cgccgattcc cctcagttct ctgatcagat attgttgaaa agcaatacga taaatcggca
     7861 gactttctaa atcgattcca atcactactg gttttgcaat ataaaaatcg atcatcaaaa
     7921 gaacattggc atactggatc atcaggtaac taagctcact atcttcagct cttttcctcg
     7981 gcaattgctg caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga
     8041 gcattttctg ctgctgttcc aaaagccgat cacgctcata gacttcgatc tttccaacaa
     8101 agaaaaacca ttcattgttg atctgggaaa tttggtagcc tactgccttt tcttctttga
     8161 ttttcaaacg acgaggacga taatgccata acatcgtttc ccgaatgtaa gtatctaaaa
     8221 cagcggttgg taactttttg ctccgtgtca aatcatactg ataaaatatt tcttcgtcta
     8281 ctatcgaaaa agaaacaaaa aagctgtaaa acatcattgt ttcgtataca ttcagttctg
     8341 ctgctgttcg actaagatgc atcacgatga ttggatcgat tgcttgataa agccggtccg
     8401 actgatagag taatttcttt tctttcaaag ttgcgtacgt acttttttca ttcaatagtc
     8461 tttttttcgt aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg
     8521 tttctaatac acggtccaat cctagaatga acggtctttt ttctggtgta ttttgcaaaa
     8581 aaagcggtcg ctgatcttcc gggatatatt ggaatagttc ataataaaaa tatcgtatct
     8641 gtagctcttc tccgtataat tgaccgtttt tgatttgtaa tccaaattcc tctaagagct
     8701 ggttcaattc tttgatcttt cgaaaaacag aagactcact gatattaaac gctgtcgcta
     8761 atcgaacgat ggatacttgc tgatgttcta ataaatagac gagcatctta aacttcaagc
     8821 tttcctgcaa taaaaacaat agaatttttt ccaaacttac atcttcgtcc aacacaagca
     8881 gcgcctgata ctcatttcgc tgtacttcta cttttttttc catcattcgg ccaatcaatt
     8941 caatatcttc caaatattga tcaaacgagg cttttgacag ttggacatgc tctctcaaac
     9001 cattgataga ggctgttccc ccttgcagaa caaggtttcg caaaatcagg atctgtaact
     9061 gctcttttct ttctaataat gcttcaatct tcataggcag tattcgccac ctttgaccac
     9121 accatatctg gcacacggta ttctggctgg aaaaatagct catgttcttc taactgttca
     9181 aacgtccatc cttcttctac tgcaattgtc agttggtcaa gaaggtggaa catctctttt
     9241 ttgctttgga gctgtgctcc aagaatcttt ttttcagaat caaatagaaa tttgagttta
     9301 actttgcttt gatttattgc tgtaagcttg tagtctacgt atcctgtttc aattttttgg
     9361 ggataaaaaa tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac
     9421 tgattgccga ctggacgata ggttccctga tcctttgtct gtgagccact aattgtcttg
     9481 ctgacatttc gtgctgtacg gacagcgtta tttactagag aaacatacat tttttcattt
     9541 gttggacgaa aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt
     9601 tgcaagtagt catctaccca gatcgttcca tcatcattca atgttaattg ttcttcccac
     9661 atctgattgt cgggacgaga atgattagcc agcaaaacaa gatcatagtt ctcctttctt
     9721 ttttccgtct ctacaatagc ggtttcattt tcggtcaaag acacaacttg ttcttctaaa
     9781 aaaagtgaaa gcccttgatt tttcatttcc tttactaacg gttctgtcat ttcaggatct
     9841 agataacgaa aaagaattga ctttcggctt tcgtaaagat ggatttgttt ttttcttgat
     9901 gccaaccctt cagctatttc gattcctgct tgtcctgcac caataattgc aattttcttt
     9961 gcattcatga tcttttgctg aagagccgtt acgttttgta tctttttaac tgggtgaata
    10021 agcgttgatt ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa
    10081 cgatcaaaat ccaatttttt tcctcctgct aaaacgactt ttttttcttt caatcctatt
    10141 actgtctttt ctgtgtaaac atggattcga tagcggtcag tcagttcttc tttcgtgatc
    10201 caagaaagtt gtttttcact ggtaaccttt ccttttaata tcaaattgaa cccgctggga
    10261 atccatccta acttcgattg cttttcaatc aaatatattt cacttgttgg catcaattgg
    10321 cgaagataaa tagccgcatg aatccctgca aacgacccgc cgacaattac aatgttcatc
    10381 tgcattcctc tttcttataa ggtgttctac tgctaacttc tcaatcagaa aacacagtat
    10441 tcataactcg ctttcaacct tatgatacat agcgatgcag cagaatcaac cctctccatc
    10501 ataccgtgtt ctaggtctgc ttctcaataa tgtactagtg gacctaattg aagagtatca
    10561 tttctgaaga gatgtttcaa aaaatgtact cttataaaag aaaaaaactc gccttttacg
    10621 tacctctgtc caaataggaa acagaaaaga acgaaaagac gagttttagc gtgtgtaatg
    10681 taatagttag aatagacaca tcatttattt ttaattcttt aatgcttcaa caactgcttc
    10741 gcctaattga tgagcagatt gaggattttg ccctgtaaga agccgcccat caatttgaac
    10801 cacttctgaa aaagctgctc cagactgata gtttgctcct ttttctttca aagcatcttc
    10861 tgctaagaat ggtacttcat tcgttgtacc atttgcttcc tcttcttcat tactgaaccc
    10921 agtcactgta cgtccagcta aaatagattt tccagactca tctgtaactg gcaacaatcc
    10981 tacaacaccg tgacaaacag ctgagaccag cccttcattt cgatagattt gtgaagcgac
    11041 tttcccaaga tctattgctt ctggaaaatc ccacattgtt ccgtggccac cagcataata
    11101 aaccgctgca taatcatttg catccacatc atcaggacgt aaggtatttc ccaaggcccg
    11161 atttctgaaa tcttcatctt cataataggc ccaatcgatt tcatccatat tcaaaacact
    11221 ttgcggttct aaaggtacat atccgccttt aggactgaca aaatctgcat cgatcccatt
    11281 ttttactaat acatcataaa aatgagtcag ttcacttaac cacaaacctg taggacgctc
    11341 gatcttttcg tacttttcta catttgttaa tacgatcaat actttcattt tcccatcctc
    11401 tttctataaa aattgcgtta ttgataacgt gctttcaaga aattatataa tgggcttggc
    11461 aaataaagct ctttatatgc tttttcaaaa ggtttcgtta caaattcatc ctcacggttt
    11521 tccaataatt tctctgccca gtcaggatcg acgatcattt gctgtccaat tgctgcaagt
    11581 tctgcatatt tcaatacctg ctctacatct tcgcgattgc ggatcccacc gacaccaact
    11641 aaagggatct ttccttgaat cgtgttatgg accacttcaa gaatcgattt atcgttgtat
    11701 ttatcagaac gagctattcg atcatacata tttaatgaaa catgcagata atctagtttt
    11761 gactcacgta atcgttcaag aagccagatc gtgtcttcaa aacggatacc tggtgtttca
    11821 tattcttctg gtgagaaacg ataccctacg atgaatggtt ttttagcata ttgttcaacc
    11881 gctgagaaaa ccgttgttaa taattcttca ataaaacgat aacgattttc caagctaccg
    11941 ccccattgat cctctcgtct attcgaatgc ggagagaaaa attgttggat caaatacgta
    12001 tttgctccat gcaactcgat tccatcaaat cctgattcaa tcgctctacg tgtggctttg
    12061 ccaaatgctt ggattgtttc aacgatttct tcttcactca ttgctcgtgg tgtttccgca
    12121 tcaggacgtt ttgctgcaac tgcacttgca gatacaggct gttctccaga taaagttgct
    12181 cgacttgtca ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg
    12241 attgctttcg ctagctcact taatcgagga atcatttcat catgagcgat gctgagttca
    12301 cctggccagc cttttccgat atcttggaca tttgcagcac cagtaataac agcaccaaga
    12361 cctttagaac gttgtttata ataagtgatc tcatcttcgg tgatcactcc attgaaaaag
    12421 ctgagttgtg tcgtcatagg cgacagcatc aatcggttct tcaattgaac tcctgaaggt
    12481 aaagtaattg attgatcaaa ttgtgacatt gtcattcctc ccataattcg ctctgattaa
    12541 cctatcgaga atcatctatc attaaaccac tcgattagtt gtacatgcaa ctaatttgct
    12601 taaaaaattt tatttttttt gtaacttatc tgttgcatca ttcattgtct gggctaattc
    12661 tttacttgct tcatttccca aaactgcttt gtatgactga tgaagttctt cccagctacc
    12721 atcgacttcc ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg acaagcgacc
    12781 ttcgctaact gttttgacgt atcctttata ttctaatttt tcaacaaaac gagcaatcgt
    12841 tgatggggcg gaatagagca tttgtgcaat atctttttgt ggtattccat ctttttcttt
    12901 taatatcaat aaaataaaac cataagttgg tgccagacct gtccttctaa acgcttcatc
    12961 agctaattta ttcaacatgc gatctagctt tttcacgcta aagaaaagac attcatctaa
    13021 cgctttttca attggctttt ccatttcatc ccctccattg gcgtacatat catagtatga
    13081 tttttatttt ttgtcaaaaa acacggaata atgtccgcct cctctgtcta gatttgaaaa
    13141 aaagaagtag ccatcttcaa agaatttcgg cttgttttcg acaaaactcc ttctggaaca
    13201 ccgtgaatca gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa aattttgtga
    13261 aaatggcttt ccacattttt gcataaattt ggcttaatac cgaaaaactg gcttttgaac
    13321 accgtttata tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa
    13381 caaaaatagt tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc agctgattgt
    13441 acaccgttta ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt
    13501 caaaaaacag cttctcatgt tttatgacta tggtgacttg tgatcgagga gttggcagga
    13561 gaatactgtt tattcgtaaa gaaggggctg tgacaagact tttgtcacag tcccttattt
    13621 ccttttatta taggatttcg ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt
    13681 ttttctttaa ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca tagatatatc
    13741 cataacgttt tgacatttgt gaagtagaag cgctgacgat atcaatgcag ccccacgacg
    13801 tataaccaaa taaatctact ccatctttga tagcttcctt catctgctca atatgctgct
    13861 tcaaatagtc aatgcggtaa tcgtcttgaa cggttccatc ttcttctact ttgtctatag
    13921 ctccgagtcc gttttcagct atgaacagtg gtttttgata cctatcatat aattgattca
    13981 aagcaattct caaaccctta ggatcaatct gccagcccca ttcacttgat ggaagatacg
    14041 gatttttaat tcctccagtt attaagtttc cttggacccc ttcccaattt tctggatgag
    14101 cactgactgc actagacatg tagtagctaa aagaaacaaa atcaacaggg taggctgcta
    14161 agatttcttc atcacctact tctattttta agttgacacc tttttcttca aacattcgtt
    14221 gcgtatacgc tggataatat cctcttgctt gaacatcact aaagaacaaa gaagttcttt
    14281 gctgctcaat tgttttttga atatcatccg gatcacaaga atacggaaca agaagctgat
    14341 agctgatcat acaaccgact tgtgaacctt tgataatttc atgacaagct tttgtagcta
    14401 aagcacttgc tataaactga tggtgtgcac cttggtattt cgcttgttcc aaatggggat
    14461 ggttttcttc aattactcct acgctaacaa aagggtgatg ttttacacag ttgatctcat
    14521 tgaaagtcat ccaatatttt actttatttt tatagcgttt gaatactgtt tcagcgaaac
    14581 gaacgtaaaa ctgaataagc tttcgattag gccatccacc atattctgta accaaatata
    14641 acggcatttc ataatgggaa agagaaacga ctggctcaat cccatatttt agacattcgt
    14701 caaacacttg atcataaaaa aataatcccg cttcattggg tgtttcttca tcaccatgag
    14761 gaaaaattct tgtccatgcg atagacatcc gatagcattt aaaacccatt tcagcaaata
    14821 aacggatgtc ttctttaaag tgatgataga aatcatttcc gtgtctttta ggataataat
    14881 acttgctgtt gggatcctgc gccgctttta cttgctgatg cgtcatcata tgccattgat
    14941 ctgtccattt ttctttaggt aaatcgctgt cgaatgtata cacatcagac acagataatc
    15001 ctttttcatc tacatcccat gcaccttcac attgattggc cgctgtcgct ccgccccata
    15061 aaaatccttc tggaaatttt ttcatatcga tccccctaaa cttgctagtt ttcttgtttg
    15121 attatttttc ttatgactag taatgatatt tttgaatcta ctactatttg taacaataac
    15181 cattgtggtc ggatcatatc cctctttgat taattcttgc aaatctactt ccatcaataa
    15241 atcgccttta cgtacttttt ttccatcaga tactgcactt tgaaagtatt tgccatttaa
    15301 attcactgta tcaataccga tatggatcag tatctctgct ccttcttcac tgactacccc
    15361 aattgcatgt ttcgttggaa aaactgttga aacttccccg tttacagaac tgtagatttt
    15421 tccgtccgtt ggaatgatcg caaacccttc tcctaaagat ccactagcaa atgttggatc
    15481 gtttacttca gataaatcaa ttatttcacc tgctgcagga gtacttaaca ctatatcctt
    15541 tgaggattct tcttcgattt catccttgta gccgaaaaga aaagttagca tacaggaact
    15601 gatcatcgct aagaaataac tagcaactag ccaaacaaat ccttcaccaa tataaatcgg
    15661 gaaagacaaa atacttcttg tagcaactgc caaagcaccg gctcctgcgg caccagctac
    15721 tccaccaaat atagctccac atatacaagc aatgtaaaat ggtcgtttat atttaagagt
    15781 cacaccataa acagcaggtt cagtgattcc aaataatgct gtgataaatg cagataaaga
    15841 taaacttttt actttcttat ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg
    15901 cgcagctacg gcagtcatac atgctggacc tagcgtatca cgaccgtaga aagaaagatt
    15961 gttggtcatt actggtacaa gtccccaatg taacccaaaa atcactaaca cttgccaaaa
    16021 tccgccgata acagcaccag ataaaacagg gctaaagtta taaacagcta aatatccagc
    16081 tgcaatcagc tgacttgcat aatctgcaat tggacctaca actaataaaa taattgggac
    16141 catcacgatg atacaaatga atggtgtcaa taaatttcga atactttcgt gcaagctttt
    16201 gcgaatctta ggctcaatat aagaaagaac ccatacagct aaaattgctg gaataaccgt
    16261 acttgtatac cttgctagaa tcacgggcat ccctagaaat cgcaaggtta tgctatcact
    16321 atatgcactg acaatcgtag gataaacgag agctgctgca ataaccatag cgatgaaacg
    16381 atctgtattg aacttttttg cagcagtata tgccaaaaat ataggcaaga aatagaaaaa
    16441 tgcatcagct gctgcattca aaatgatata agttcctgat tcagtagtta ataaattcaa
    16501 actcgtacat aaggcgagta ctcctttgat caaaccactt cctgccaaga cgcctaaagt
    16561 cggggcaaaa acagcggcga tcatgtctat aaaagagttt aaaatgcctt ttttctcagt
    16621 tcctctcttt ccactagatg catcatcttc tagtttcatt tgtttggata atacgtcata
    16681 cacttcattt actgcatttc ctactacgac ttgaaacatt cctccagctt cgactacagt
    16741 gatcacacct tctagttgct ctaccttctc cttatctgcc ttcttattat cttttagggt
    16801 aaagcgtaac cttgttgcac aatggtaaac attgctgaca ttttcttcgc ctccgacaaa
    16861 tcggacaata tctttcgcta attgtgaata gtccattttt acttccccct tgttaattaa
    16921 tgccgtagca atccttctta caagataagt atagttctta gaaaacggtt tctccattca
    16981 attagtaccc cttctaatag cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc
    17041 gagcaaatca ctcactgctt gaaagaaaac aagtatatcg tttctcttat agtcaaagga
    17101 gacaaaaaaa acacgcttga tcttcctttg ctgatgtata agtggtatct caagctgata
    17161 ctctgtgatt tttgtttcta cttggctttt gataagacag cacaacaaag tctcggcatt
    17221 taacggaagc ataactaggt cagaactagg agagattagt tgctgaatgg aatctatctt
    17281 tttatggatt tttatttgat tttcttcttt gtagtaatga tcaagcagtt ttgttttctt
    17341 tttttcttca actatggtca gcttttcacg caaaatctga taaatctccc aagattcaaa
    17401 ctcatctaga acactaggta gataaatcaa atcatcccac tcaaaaataa gctcttgctc
    17461 agtagtcaaa attgcatcat attccgttat tttgtttgat tgatttttga aaagatacac
    17521 tggttctatc cggcattctt tgatccacat gttcatactt tgttgaatct gtttttttag
    17581 tgtattcaaa atactaattg gctggttact aacaatcagt atctcccctt gttttcgaaa
    17641 aggattcaac gcttcggcaa gatacaaaac aaaataagcg ctttcagcta aattgggacg
    17701 taattgaaaa tgtattggga agaaacgccg aattaaataa atttctaaag gataacggga
    17761 gatgatcttt tgtacaaaat gattcatggt attatgtccg gcatccatcc tcgttttcat
    17821 ttgtttgata tgggttagca aaaattctgt ttcatggaac aataacgaaa caggaagatc
    17881 taaaaaacga ataatcgttt gctcaaatgc tcttagattc ttctctattt ctttgttttt
    17941 ttcatcatta atcatcaaat aatttaactc taatagtcga ttttcaattg cttgtttttc
    18001 ttgattggaa aaagaatagg gtagttctga tgataacttt tttgtgaggg tctctaccat
    18061 cggaataaat aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt
    18121 caaaacgaga taccgagaaa atcgtatgaa gtcctctcct gaaacaatat aattatatga
    18181 tataagaacc tcttttaatg tcttttggac agtcggcatg atattggaaa aaattgtact
    18241 gatttgttga ggaaaccttg cgtgttggat caccgtttct gttccaacaa gagataagaa
    18301 aattcttttt gaattttctt cagcaatgat ttttagtcct tttgtcgacg aaacttccag
    18361 ttctaattta ggattgcgct cgatccaacg caaaatcgtt tttatttgta atgatacggc
    18421 tgtttttgaa agaaagaaaa tgtctgctat cttttgcata ctgacatacc ctttttgaaa
    18481 caataagtac gtcacaatag ttgaagctcg gaaatccatg ctggaataga ttttatgttt
    18541 cgtcacctct tgtatgattt gctgtttagt ttcagattca attgattcta aaaaataacc
    18601 tgaacgttta tttgactgga taatgatttt cttctcgtag atagcaagca tatttttgat
    18661 ttcagtttgg atcgttttct tgttggtacc taaagcttca gctaattctt cgcttgttat
    18721 ccaatgattc ttatttctta atactacaag aatttggagt tgtcgtttat ttaagtccat
    18781 ttgcttacac ctcctctttg ttataaacat acaggaaaaa cctctcaaat gacaatagtc
    18841 acttgcagag gtttaaaaat catttgaaga aagatctata ttcaaggttt ttaccattag
    18901 actggataat ttgtttataa tattcaaaac tatctttttt caatctccta aagcttccgc
    18961 tcccatcatt ttgtctatcc acataaataa agccatatcg cttcctcatt tcccctgttc
    19021 ctgccgatac gatatcgatt ggtccccacc ataagtaacc aatgatttgg caaccatctt
    19081 ttattgcctc agcaatttcc tgaagatgta tttttagata ctcacaacgt tttggatcgt
    19141 ggattcgatt caattcatct ggtgcttcat ctagtccaat gccattttca actatgaata
    19201 atggtaattc ataacggtct gtcaattcat tcatgacata acgaaaccct agaggatcaa
    19261 ttggccaact ccaaggttcg ggagattttt ccttcaaaaa gggattatcg aaaccatttg
    19321 ctccgccagt atctacgcgc atttctgctt cttttttata gacagcgcta cgataataac
    19381 taaatgcaat ataatctgcc gtgttagctt gcaagcactg ttcgtctcca tctaacatta
    19441 ctggtgcaca gtcttcttcc ttccatgtcc tgtaaatata agctggataa tgccctcggc
    19501 acatgacatc ggagaaaaac catgaattgc gtttaaattg cagtgaacca aatacattct
    19561 ctggatcaca gtcatatgca taagtcgcta atgcagaaaa gctacacata atacccatct
    19621 tagcatttgg atcgattttc tttaataatt gagtagcacg ggcgttcgct agaaacatat
    19681 gatgacaggc ttgataaatc actttttttg ttagtgtagc aatgggttca agtttatctc
    19741 tagcagggaa tgtaaccaat ccagcagctg cataaggcat acgaaaagca ttattgatct
    19801 cattaaaggt catccaatat ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat
    19861 aaaattcaaa aaagtcgatt aattttcgat tttgccaccc cccatactct cctaccaatg
    19921 ctaagggggt ttcataatga ctaagagtaa ttactggctc gatatcatat cgatttaatg
    19981 tattgattag tctgtcataa aatacgagac cagcctcatt tggcttctgt tcgtctcctc
    20041 ttggaaatat tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct aactccttca
    20101 gtaaacgaat atcctcttca aatcgatgat aaaaatcaat cgcttcatga gaaagataat
    20161 ggagtgattc gtctaaagca atctcccaaa tctttttttc ttcattccac tgaatactag
    20221 gatgctggtt catgatcccg ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca
    20281 accatgcacc ttcacattga ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa
    20341 atatttcctg atccataact atctctcctc gctatcaaca atttcttact tgaagtatag
    20401 ctcgattcat caaaacaaga tattctaact atttcggcag aagagaagaa aaaaattgaa
    20461 tgctactctt catttttaat atttatatat aacaaataca taagacgatc cccgaaagaa
    20521 aacactcgtt aaccatctaa gcaaacgatt tattttactt ccaacacaaa tgcttcataa
    20581 ggtcgtaaat caactttgcc gtctggtaac tgtttcagag gataatttga cacaataacc
    20641 cttaaagctt cacgtggaat agtgaacgtc tgcttttcac tggacatatt acaaataacg
    20701 agccattgct ggtcttcata tatgcgagaa taggcaaaga catgctcagg cgtcttttcc
    20761 actaattcat agtctcccca gacgatgatg tcatgttttc tacgcaaatc gatcaatttc
    20821 ttgtacatat aaaaaacaga atcttgatct gctaacgctt cttctgcatt gatttcttta
    20881 taatttggat tgactcgaag ccatggaatt ccagtagtaa acccagcatg ttcacgggcg
    20941 ttccattgca taggcgtcct agcattgtct cttcctttcg ccttgattga ttccaagatt
    21001 tcctcttttg taaatccaga agaaatcctt tcgttataca tattgattgt ctcaatatct
    21061 tttgcttccg cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc tccttgatag
    21121 atataagggg tgcctttcat catatggagc aagatagcaa acatcttggc actttctttt
    21181 cgatacacat cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg attattccaa
    21241 aataaactat tccatccttc atcacctaaa gatgtttgcc atttggataa tacttttttc
    21301 agttcagaga tactcaaggg tttcaaatcc catttgtctt tgccttcttg ctgatctaat
    21361 cctatgtgtt cgaattggaa gaccatggat aattcatttc ttttaggatt ggaataaagt
    21421 ttagcgattt cggtagttgc tccccatgtt tcgccaacag tcatcagatt tttgtcacca
    21481 aaagttgctt gattcatttc ctgaagatac tcatgcagtt taggtccatt acttgtgatt
    21541 tctttatccg gttctttgcc aatcatatcg atcacgtcca tacgaaagcc cccaatacct
    21601 ttatcgatcc agaaattcat catttgataa atctcttggc gaacctgttt atttttccaa
    21661 ttcaaatcag gttgacgctt gctatacaag tgcagaaaat attgccccgt tttttcatcc
    21721 aactgccaag cagaaccact gaatattgag cgcaatctat taggctcttt tccattgacc
    21781 ggatcacgcc aaatataata gtcccgataa ggattttctt tatttttacg ggcctcaatg
    21841 aaccacggat gttcatcaga agtatgattc accaccagat ccatgatgat acggatattt
    21901 cttttctttg cttcttcaat cagttcttcc atttcttcca tcgtaccgaa ttctgccatg
    21961 attgcttgat aattactgat atcataccca ttgtcatcat tcggagactc gtatactgga
    22021 gaaagccaaa ttgcatcaat acctaaatac gccagataat ccaacctgga aataatcccc
    22081 cgcaaatctc caataccatc ttgatttgaa tcttgaaaac ttcttggata gatttgataa
    22141 acaactgaat ggtgccacca tttttgttcc atgattttcc tcctataaat ggatgtttct
    22201 attttttgct taatcattta ttttagtctc tctcactaaa aattgtaacg ctttcaaata
    22261 gctattgcac cttgttatcg gtaacagaat aaaacaaaaa aacagctgag gaaattccct
    22321 caactgtttt ttgaaaggat tgatttatgc agggaagaat gctgatttca caacttcttt
    22381 ataaacggtg ttcactcagc tgtcccttgg tattagctca aaaaacggca aaatataaga
    22441 aactattttt tcgttttttt ctctaatact caggccagaa cgctgatttc acaacctctt
    22501 tatttcacat tcaatatcca catgaatccc acaaatacaa agaacagacc atacatgatt
    22561 ggagatactt cttttcctct tttagctgct aacatggtaa ttggatagaa gataaaacct
    22621 aatgcaatcc catctgaaat actataagtc aaaggcatgc cgatcaagat caagaatgaa
    22681 gggatcgcaa tctctaagtt tccccattcg atttgtcgca aagattgtgc catcaatact
    22741 cctaccataa tcaatgctgg tgcagttact tgtgaagtaa caactgatag taatggagaa
    22801 aagaacaagc ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct
    22861 ccaacggcga taccagctga tgattctaca aatgcaccaa caggagaagt accaaataag
    22921 gaacccgcaa gcatagctgt tgaatcagaa gctaaagctt tccctacacg aggcatcttg
    22981 ttgtctttca tgaaacctgc ttggtttgct aatccaacta aagttcctgc tgtatcaaag
    23041 aaagtcacaa gcaagaatgt cagcactacg acccacattt gaagagaatt gatgtcccct
    23101 acatgtttta atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc aacaatttca
    23161 gaaggcattg gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg
    23221 aagatgccac ctggtacacg ccgaacaagc aagatagcag ttacgactaa tccaaaaatc
    23281 gtcaaccaag tagaaccaac gttgagtgat cctaatccta ctaatgtaga ttcattcgaa
    23341 acgatgatcc caccttcgct cagaccaagg aaagcgataa atagaccgat accgccagaa
    23401 atcgcatatt tcaaatctgc tgggatcgca tcaatgatca tttcccgcag cttgaagatt
    23461 gtgatcaaaa taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt ttcccatgga
    23521 atccccattc ctaaacaaac agaataagca aaaaaagcat tgatcccaag agcaggtgcc
    23581 gttccaattg gataacgggc taataccccc attaaaacac agccgatcgc actggctaat
    23641 gcagtcgcag taaacactgc tccttcatcc attccagaag cacctaatac agttggattt
    23701 acaaataaga tataagccat tgagataaat gttgtaaatc ctgccagtac ctcacgtttt
    23761 accgtggtgt tcaatttttc tatttcgaag taggaaagta ttttttcctt catcttccat
    23821 ccccctaaat ccgaacatta taaataaagt ccgttaaaat ttcgatttat taataaaaca
    23881 acgtgtttta tcatatacta aaacaaaaca taagtaaaca aaaaattcgg attttaagca
    23941 aaatccgaac gttccatctg attaaatccc tttatctcaa agttcatgaa cattcacttt
    24001 ggattacaag aatttcttta ttgtgttaat aaagtttctt cattctagtc tcaaaaatca
    24061 atagtgtgat ttgattttac catttcgttt ctgttcttct ttgatgaatt cttttgtatc
    24121 gacaggattc agattattta gtccgccaaa acctgtatcg accatttttc cccagccttt
    24181 tgtcttcttt tttcctgatt tgagattctt tgctcgaagc ttctcactat gttttgctcg
    24241 ccgatacttc aaataacctt ctaatcttcc cattagatcc actgtttttc ctccttttta
    24301 ttcaatcaga cgactcagct tttcctataa caaaataatt gccttcaggg tcagaaaaat
    24361 tgaaagtcaa gatgccattg ttatctgtga tttctcctgg ttcttccatg ttctcgtaga
    24421 tagtttcaaa ttcatccgta aaaaatacta aagaaggcgg tggtcctaat acctctggtg
    24481 aaaacttctg cacaaatact tttgggaata cgcctaattc taattctttt gagatgctga
    24541 gtacaatact cttaaattct tctggcaatt cgattgtttc agaaatttct gcaccaattt
    24601 tttctacaaa gaatcggcaa atcatctcta cgtcattgac ataaagcatc acacgtgttt
    24661 tttgtatcat catttgaccc ttctttctat ttgattttct ttcctgtcta taaactgatt
    24721 ccattatatc acgaaagcgc aaacaccttg tgtttgatac tattcaagaa aaataaagca
    24781 atagtttcta ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa
    24841 tgccgctctt cttatttcga ttcttttata attctgcttc tgattcatct ttggttagtg
    24901 tgtgtctaac actagttacg ccaaatgttt gatcgatttt ttccttcaac gcttcgattg
    24961 cctgtgcgcc acgtgccgct tgttcagcat tgatggattc aatgaccagc accgctgctt
    25021 gtgtttcttc cgtcagcatc gttctttggg cttcacgcca gttgagacag cgacagatcg
    25081 ctccttgttc atcatagtag atgatttctt ccggaagtgc cggagcatcg gaatctgcac
    25141 ctaaaggcag gaatgattcg ccaccttggg cttttcctaa atgcagattt cctgcgatct
    25201 tttcgatatc ttctccgccg caaggtacgc caaaagacaa ggaaatacta ttatagatat
    25261 ctacaagcgg attgattggg aaaaattccc gttcttgatt tgcacgtttc agtaaagctt
    25321 caatagaaga acgtgcacct tttttagtct tgaatgtggt aaatgcctga cgccactgag
    25381 caatgacttc gttttggctg aatgtttctt ctgtaaggta atttcttgct tcttttgctg
    25441 cctcattcaa taattgatga tacgtttctt cactttcttt tgttacgtgg ttatcgatac
    25501 catttacgga taagatttcg atggttgctt caggaaatac ttcccagaaa ttggtatcca
    25561 ctattacttt tttcatctgt tcacacctct tgattagaat aattgcttga tgaatagata
    25621 gtctgtttgg ggatcatctc ccatataaaa aacatgttcg ctgtatttga taaatccttt
    25681 tttacgataa aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc aaatggctgt
    25741 tttttgcttt tcttttgctt tttcaatagc tgtatctagt aaaaatgtac cgataccttg
    25801 atgtttaaat ttttttcgta catagattcg ctcgatttct aaaaaatgat cagccatttc
    25861 ctcagattga ctcgttcctg tatttagttt caggtaaccc gcaggctctt gatcgatact
    25921 cactaggaaa aaatcggttt ctttatcttt tagctcttct gtaagttttt ctagtgcata
    25981 agcttgtgtc aagtaatcag ctaaatgctc cggtgaatta tcttttccaa atgtatctgt
    26041 aaatgtttcg atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat
    26101 ttcgtattta ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa
    26161 attccaatct tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc
    26221 ttcttcgtca gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat
    26281 gaaaggatag atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc
    26341 tttatcttcc aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt
    26401 cgttgtacga tctactttga tcatttctgc tagtttttct tggatgattc caggattttc
    26461 gcaaatacgt actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat
    26521 attgctaata gaatctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat
    26581 ttcatcccac ctttattttg tttgtaagac tagttcacct ctttttgttg caaatgcaac
    26641 tattttcaat aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc
    26701 ttttacgaaa aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt
    26761 ttcttcgttg ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg
    26821 ttggaagttt cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa
    26881 acaagtttat aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact
    26941 gctcgcaact gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca
    27001 ttttcttcag gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc
    27061 cgtttatctt cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact
    27121 tttggtgttg gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct
    27181 tttcctattt cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta
    27241 tcaaatacat cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat
    27301 tgagccaact tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat
    27361 caagtataga agactggttt aattacggca aataaatata atgaaatctg caataaataa
    27421 aagaatgtta aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat
    27481 ggcgttcaaa agcttgcatc tgcggtaata agccccacca aacgaaaaat atgacgagct
    27541 attcttgtct ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact
    27601 aaacggtgtt ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa
    27661 gctgtttttt tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc
    27721 ggtaaacagc gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt
    27781 cattgatttc tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg
    27841 ttacatcaaa ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga
    27901 tctttttgaa tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt
    27961 caccatagtg ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt
    28021 tgtaccgacg ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat
    28081 atccgtatct atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact
    28141 cggacacaat cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag
    28201 gataaacttt cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt
    28261 ctgcatagta ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc
    28321 gtagtttatt cataagatat gtttttcctg taccaggact accagccaga agaatgaaat
    28381 actttttcat ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca
    28441 atcttatgct tgacaatttc ttttactgct tcatttgctg gaatcacatt atggcgaaga
    28501 gacttgttga tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa
    28561 agctccgttc caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct
    28621 tctttcacac ctgttcctcc atggataact agggggacat caactactgc atcgatttct
    28681 ttcagcaagg gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata
    28741 gcaatagcta atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt
    28801 gtatatacct tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca
    28861 agttctcctt ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc
    28921 aggatatttt ctttgaaagg cagatgggac ccatcataca tgacagaagt atatccgctg
    28981 tcgattgctt ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca
    29041 accatttctt cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat
    29101 ttagcggtat cgacacttgt ttgaataatg atcggcgaac ccatttcttt tgctgcgcct
    29161 agcatagcag gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac
    29221 tcttctgctg tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc
    29281 tttttatttg tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt
    29341 gcccatgtag taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg
    29401 gttatagagg ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaaact
    29461 cttttctaaa tattggatgg cttgatcgtt cacatacaat tcagaaaatt taagtccaac
    29521 ttgttcataa agtttcgcta atttatgctt atcttgggta gtggaaatct cttgtttcaa
    29581 ttgtgtaatc tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt
    29641 tgccagaact tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc
    29701 tactttcaat taaaatgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc
    29761 ggctactgta tctacatcgg ttgctgtagc attgttgaat cccatcgaat taaagatcgt
    29821 tactagcaaa gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc
    29881 tcctcggcgt ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt
    29941 ggttagcata ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat
    30001 aatcgtacca atcgttgtcg taatgaaacc taaaatgaca gcatttgggc tataaggaaa
    30061 gaaaactgga caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg
    30121 aaatgccggc acgatttcac ctaacagtag acgtacacca gctagcaata catacacacc
    30181 cactacgaat tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa
    30241 ttcagaagcg aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac
    30301 gaccatgaca gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc
    30361 ttcgatcgac tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa
    30421 taagtacccg atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg
    30481 aatgatcggt tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc
    30541 gaccaagatc aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt
    30601 tgccatccat aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc
    30661 caaaataata ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc
    30721 caaatcattc attgcttgac cattgataga ttcaatagaa gggatgatcc cttgcatatg
    30781 aaatccttca gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc
    30841 ggcactcaac acttgaaatc ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc
    30901 tgatttcttc tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg
    30961 agtcaaaata ttttcgatga taaaattgat aacgcccatg ttttgatgtg caccccaaaa
    31021 gtta
//
LOCUS       DADQCX010000027        30781 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.027, whole genome shotgun sequence.
ACCESSION   DADQCX010000027 DADQCX010000000
VERSION     DADQCX010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.027"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(35..1336)
                     /locus_tag="J8R83_001144"
     CDS             complement(35..1336)
                     /locus_tag="J8R83_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9574282.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            1634..1996
                     /locus_tag="J8R83_001145"
     CDS             1634..1996
                     /locus_tag="J8R83_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9574283.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            2005..2757
                     /locus_tag="J8R83_001146"
     CDS             2005..2757
                     /locus_tag="J8R83_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574284.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            2771..4573
                     /locus_tag="J8R83_001147"
     CDS             2771..4573
                     /locus_tag="J8R83_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574285.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            4850..5890
                     /locus_tag="J8R83_001148"
     CDS             4850..5890
                     /locus_tag="J8R83_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAZ9574286.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(5942..8086)
                     /locus_tag="J8R83_001149"
     CDS             complement(5942..8086)
                     /locus_tag="J8R83_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9574287.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(8443..9816)
                     /locus_tag="J8R83_001150"
     CDS             complement(8443..9816)
                     /locus_tag="J8R83_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9574288.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(9816..10211)
                     /gene="rbsD"
                     /locus_tag="J8R83_001151"
     CDS             complement(9816..10211)
                     /gene="rbsD"
                     /locus_tag="J8R83_001151"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAZ9574289.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(10239..11156)
                     /gene="rbsK"
                     /locus_tag="J8R83_001152"
     CDS             complement(10239..11156)
                     /gene="rbsK"
                     /locus_tag="J8R83_001152"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAZ9574290.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(11264..12277)
                     /locus_tag="J8R83_001153"
     CDS             complement(11264..12277)
                     /locus_tag="J8R83_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9574291.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(12358..12957)
                     /locus_tag="J8R83_001154"
     CDS             complement(12358..12957)
                     /locus_tag="J8R83_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9574292.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            13143..13844
                     /locus_tag="J8R83_001155"
     CDS             13143..13844
                     /locus_tag="J8R83_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574293.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            13854..16565
                     /locus_tag="J8R83_001156"
     CDS             13854..16565
                     /locus_tag="J8R83_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAZ9574294.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            17016..18644
                     /gene="treC"
                     /locus_tag="J8R83_001157"
     CDS             17016..18644
                     /gene="treC"
                     /locus_tag="J8R83_001157"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAZ9574295.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(18704..19885)
                     /locus_tag="J8R83_001158"
     CDS             complement(18704..19885)
                     /locus_tag="J8R83_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9574296.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            20137..21660
                     /locus_tag="J8R83_001159"
     CDS             20137..21660
                     /locus_tag="J8R83_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAZ9574297.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(21729..22457)
                     /locus_tag="J8R83_001160"
     CDS             complement(21729..22457)
                     /locus_tag="J8R83_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574298.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(22470..23750)
                     /locus_tag="J8R83_001161"
     CDS             complement(22470..23750)
                     /locus_tag="J8R83_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9574299.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(23891..24493)
                     /locus_tag="J8R83_001162"
     CDS             complement(23891..24493)
                     /locus_tag="J8R83_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAZ9574300.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            24738..24944
                     /locus_tag="J8R83_001163"
     CDS             24738..24944
                     /locus_tag="J8R83_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574301.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            25256..25975
                     /locus_tag="J8R83_001164"
     CDS             25256..25975
                     /locus_tag="J8R83_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAZ9574302.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(26056..26739)
                     /locus_tag="J8R83_001165"
     CDS             complement(26056..26739)
                     /locus_tag="J8R83_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAZ9574303.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            26957..29143
                     /locus_tag="J8R83_001166"
     CDS             26957..29143
                     /locus_tag="J8R83_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAZ9574304.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            29489..29899
                     /locus_tag="J8R83_001167"
     CDS             29489..29899
                     /locus_tag="J8R83_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAZ9574305.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            29913..30269
                     /locus_tag="J8R83_001168"
     CDS             29913..30269
                     /locus_tag="J8R83_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAZ9574306.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        10218 a         5437 c         6083 g         9043 t
ORIGIN      
        1 ataagaacat ctaaggtaga attccttttc tactttagat gttttttgat tcataggtaa
       61 tcagattatt tagtaagaaa attctggtct tcattttccg aaagcttcga aagccataag
      121 cgactcgttt caatgctttg atgtgggtat gcagattttc tattttggca tttgaataag
      181 gcaattcgag ggctaaacga atgccggatt catagtttat aaaagctttt tttatagaat
      241 gcagttcttt tggaacggaa ttgggcatcg ttcttacaag tttaaagaaa gtgtccgcct
      301 ctttgtcgtg aaacgcttga agaatttctt gatagtaaaa ataggcgatt cgtaattcgt
      361 cagagatcga aagcagacga tccaccactt cactttcggt gagatacgcc caaccaaaat
      421 tgcgccattt ggtccatttg tcataaacaa gcttgtcctg tcgtttgatc agaagccgag
      481 acaacgcctt taattgtcga taatatttgg cttgtgttgg atcgtttcga tcaaagcttt
      541 tcatgattcg tacgcgaata tcctcaaatt tacgaatgag atgtttgaca atgtgaaaac
      601 gatccacaac gagttttgcc tttggaaaac attcctttat cagagaggca taagaaacat
      661 tcatgtccgt cacgatgacc tttaccttca atcgtgcgcg tcgttcaaat tgcataaaat
      721 aagaaacgag agcctttttc ttccgtgaag gaagaatatc cagtaatttt ccagtatcgc
      781 catccataca agaaaaggag tagggaccga cttgattttt cagtgaacga aattcatcca
      841 ttaataaaca acgcggtaac caatttcttt ttacttttgt catggggatc agagaagcga
      901 gtgtccgaga aacggtcgac caagaaacgc cgcaatgctt agcaattgtc gtcattgctt
      961 gtttttcagt tagctcttct aaaattttat agcgcacttg tttagcgata aagcagtttc
     1021 tatcgacaat gtaggtattc gccgtaaaat aggtgtggca gccacgacag tggtagcgtt
     1081 gtttcgctaa agcaagataa gtcagttggt tcgcacattt attaagttga atgagcgatt
     1141 ttttctttcc gttcttaacg atcatgcctt catgattcat ctgtttacac aaaggacagc
     1201 gacgaatttc tttacttaac gtcgcagaaa caacaagact cttgatattc ttaatgctct
     1261 tcgattccac atttgtgatg aaaatgtttt tatctttgat tccaagtagt agtttgatat
     1321 gatgaagatc aggcatacag aacgctcctt tgattgtgtt gtggtgattc aattctaacg
     1381 gagcttctgt atgttttgtt ttttcatgct caaaagggac cgatagaatg attttctatc
     1441 agtcctagaa attatagagc cactttttgt aagataggaa gaaggagttt aggacggatt
     1501 attgtcttga actctttttt tagttgtttt aaagaaaatg acaaaattga aagaagaatg
     1561 atagttgatt cgaaggcaga attgttcgct tttttctata atcagtatat aaagtaagag
     1621 agaaggggaa aaagtgaaaa aacttctgat cggtctactt gttttcatcg ttgtggtact
     1681 tgcaggggtg aaaatcgcag attacgtagt tatgggtgga gaagaatact atgtacaaat
     1741 tacgacagat ggtacaaaaa cagtttcaaa atcagactct ggacaagaaa cagtcaacta
     1801 tagatatatc ctgcctggct atacgaaaga gggtaaggaa aaagaactgg acttcaaggg
     1861 acaattgact cgaccgcttc gtaaaggagc atatttaaaa atcacctgga acaaaaataa
     1921 aggtgtcact tcgtatgaag aagtcgaaaa aaaagacgtg ccgaaaacag cactggaaaa
     1981 actaattaaa gggtagggaa agaaatgaac aaaatagtcg aagtacagaa tgtaacaaaa
     2041 gtatacggaa aaaacaatga gaaaaagacg caagcattaa gcggcatcag cttcgatgta
     2101 gaaaaaggcg aatttattgg gatcatgggc gcttctggtt ctggtaagtc gacacttttg
     2161 aatattttat ccacattaga taaaccaaca gatgggcata tccgaatcaa tcaaaaagat
     2221 gtgaccacat taaaaggaaa tcaactagca gattttcgtg cgaatgagat tggctttatt
     2281 ttccaagatt tcaatttatt agaaagcttg acagcacaag aaaatatcgc tgttcctctt
     2341 tctttacaag gcgtcagacc aaaagaaatc aagcaacgtg tccaaaaaat tgcagaacgt
     2401 ttatccatct ctcatatttt ggaaagctat ccttctgaga tttccggtgg acaaaaacaa
     2461 cgggtcgccg ccgcacgtgc attgatcaca caaccaacga ttctattagg ggatgagcct
     2521 acaggtgcgc tggattccaa aagtgcccgg gatcttttag atacgatgga cgaattgaat
     2581 acaaaagatc atgtatcgat tcttcttgtg acgcatgatc cgttttctgc aagttattgc
     2641 caacgtattt tattcatcaa ggatggcggt atccatcaag aagtgaaacg tggagatcaa
     2701 agccgtgatt ccttctatcg agaaatacta tctattcttg gaaacttgga acagtagggg
     2761 gagattgact atgctttgga aattatcact tactgggatc aagagccgtt taagagacta
     2821 cttggtgtta ttctcaggat tagttatggc atctgctatt ttttacatgt ttgaatcaat
     2881 ggcaagcaac gaagcttttt tgaaaagtaa tacgatcgtt gcggctacag ttatcatttt
     2941 ccgattcggt tctgttttac tagggatcat cacattcgtt tatattttat atgcaaattc
     3001 ctttttgatg acgatgcggc aaaaagacta tgcaatgttt atgatgctgg gagcaaaagg
     3061 cagaaaaatc gcacagatga ttttttctga aacattctta gtagggatcg cagctacttt
     3121 agtgggttca gctgtcggtg taggattgac aagtatcgtc caccgattat tagtggatca
     3181 gttagatctc aatatttcgc attttacacc ttttagtatt cacgggttgt tgatcactgt
     3241 tttgtttttt gctgttttgt ttttattagc tgctgttgtc aatgcttttt cgattgtcaa
     3301 aaaaccgatt ttagcattga ttcgtgcgga tcagacacca acaagaatca agcagcataa
     3361 attcttgttt ttccttgaag tagtactggg aattgctttt ctaggctgcg gttactatat
     3421 gatgaaacac gtggggacct atcaagtctt tggtataggg gtagccttag ttacgatcgt
     3481 attaggaact tatttcattt tccattctgt gatcattttc tttttatcat tactaaagaa
     3541 atcagaacag atttcattga aaaaattgaa caatttcaca ttgtcacagt taaactttcg
     3601 tattcgtgaa tatacacaaa tgctctcaat ggtcgctatg ctgtttgcct tggcactggg
     3661 cgctttgacg gtaggattag gttttaaaaa tgaaattgca gacttgacag aaaacaattc
     3721 tggatatgat ctagtgatga ataatcctcg ggcagaagat cagcaaaaaa tcaaagaact
     3781 ttcaccaaca ctttctgctt cttatactca aaaagaagat gcgggaacga tttactataa
     3841 tgcaagtgaa tttgcggctc aaccattgat catgataaaa catgaagatg gaacaccgcc
     3901 gaagatcacg aaagaaaaag ttcctgctaa aaaaatgaat gaactgactg tacaagagga
     3961 acttcgaagc tatgaattgc cggaacagca agaaaaagaa atcaaggtag tcagtcaatc
     4021 agaatttgat caactgaact tgccacaatc cactttacag ctagttcagg taaaagactt
     4081 ccaagcaaac ctgaaaccaa tcgaaacact tgttgctcaa aataaaatga acaatccatc
     4141 tttgcaaaaa gtagagtaca gcaaccagaa atatgaaatg tatgaagtgt ataatggtct
     4201 attctctggt tttgaattta tgggattctt cctaggttta gctttcttga ccatgcttgc
     4261 tagctgtttg atgttcaaga tcttgtcagg aagcaagagt gacattgctc gttatgaaat
     4321 gcttgaaaag ataggaacac gacgcgggtt gcttaaacaa tcgatccgta gagaagtagg
     4381 cgtgttattc ttagcaccag gaatcttagg tgtagtccat gtcttattcg gattacaaat
     4441 gtttggtcta ttcatgcaaa atccatacaa agatatttgg gttccgttta cgatattctt
     4501 cgtattgtat ttcatctact atgtactgac gacatggtta tatactggaa tcgtattgaa
     4561 aaagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaag caaaaatagc
     4621 tcctcatatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
     4681 tgttcggaaa aagaggttgt gacaatattt ttgtcacaac ctttttttca cggtctttta
     4741 ttagaatata gtaaattttt tctcgttact cacggaataa gctgttaaga aaacggtttc
     4801 catgtatact ggaatcagtg caaatgaaag aaaagagggt gcaaggaaca tggaaatcaa
     4861 tgaacaaaat tttggcgaaa actatcactt gattacgatc acgaatcaaa atgggacatc
     4921 tttgtctgtc agtgatcttg gggcacgggt tgttcatttt caaacaataa tcgataatga
     4981 aaaacgagag ttgatcttag gttttgatga agcaaaagaa tatctagaaa aagaccctta
     5041 tatcggtgct tcaatcggac gtatggctgg acggattacg aatggcacat tcaaattaga
     5101 tgatgaaacg ttcgaagtaa aaacagaccc ggacactggt cattgtttac atggtggtgc
     5161 acctagcttt gaagccaagc agtggcatta tacagtcatc aatggtgaaa acgaagcatc
     5221 ggtcattttc tatcagacta gcccagatat ggaaaacgga tttcctggaa ctttagatgt
     5281 agaagtacgg tatacgctga cgaacgatga tacatggcga gtgacggtcc aagggatcag
     5341 tgaccgcaaa acagtattca atcctacaaa tcatgtctat ttcaatttaa ccggtgatcc
     5401 agcacagtca atcgacgaac atatactttg gttgaatagc cgattatttg ctacgctcaa
     5461 taaagataca acgcctacag gagaagtagt ttcagtaagt ggcacagcat ttgacttcca
     5521 acgtcctaaa aaattaggtg aggtctttgc cagtgatttt cgccaatcaa tgatagtggg
     5581 cggcatcgat catccatttt tgttgaaaaa acaatctggt ttactaaatg ctgcggaatt
     5641 gacaagccca gatgaaaaag tatcgatcca agtaaaaaca gatgcttcag gaatcgtgat
     5701 ttttacagca aattttggag aagatggacc ggaaatgcgc gggaataaat tagtaaatca
     5761 tggcggtatc acatttgaga ctcaagaact gccaggagcg gagcgacttg aaagttttgg
     5821 agatgtcact ctggaaccta accaagtacg cgagtttgta acggaataca aaataaatat
     5881 aaagaaatag aataaattaa aaagggagtg tgacagtgtc acatcccctt tttaatttat
     5941 tctatttctt taaaggcaga tcaagccaga atgatttgtc taaacttaac aaggttagta
     6001 caggaacagt tgcagcttta actgtacgag tagttgtttc tggtatctgt cttgccgtaa
     6061 aattgttcca caaatcccag attgaagcga cacggaagat ggaagaagcg ttgttgacgc
     6121 gttttatcgt tgaaaattct aatcctgtga ttggcacgcc atctgttgtc catttgattg
     6181 gcacatcgaa tcgcttagac atattgagga tttcagcgtt tgcttcttca gttgttgctg
     6241 cttctttttt cggttcatca tattttgtca ggtcgtacgc ttcgatgatc gcgttcaatt
     6301 tttgtgaata ttggcgatct gtagcataac gtccttccaa atatttggtt gcttctttgt
     6361 agtcttttgt ttccgacttc caagttggtt tgtagaaatc aggattgcca gtcagtccat
     6421 ttttgatcaa gtcggcatag tcttccaaac tttccttgta agaaggatat ttacggaatt
     6481 gtgcgcggat ttggtagctt tgtccggaac tatcttgttc aagtgtattg aaggtcacgc
     6541 tgcttccttt atatgatcct ttgataccaa aaaggttatg atttggttcg cttgataata
     6601 agctgtttcc agatccactt tcaaggatag cttgagccat catgactgat gcgtagattc
     6661 cttctttttg cccgatttcc tgtgcatcat ctgcaatctt tttcaagaac tgatcagttg
     6721 tttggttttg actgaaatgg aacgagccat ctaatccatc taaaatagat gagccgcctg
     6781 tcagcgaacc tgaagcagca ggtaaacctg ctaagtttac tcggacagca aaatcaggcg
     6841 tgaaatctga aatagaagtt actcgaactt tatctcctgg ttgaggcgca tggataaatt
     6901 gtccgttccc aatatagata cctacatggt gagtaacacc ggaagaaggt ccccagaaga
     6961 cgaggtcgcc aggttgggcc tgacttactg gaatctgcgt acctgcatat tgctgttcgc
     7021 ctgtccagcc accgatataa tgaccggttg ctttcatata tacgtaataa gtcaaaccag
     7081 aacagtcaaa agtatttgga ccttttgctc cccatacata tggttttcca agatgcttga
     7141 atgcttctcg aacgattgct tgttggacat tcgttgtatt tgtaggcaat acagcatcaa
     7201 ttggtgattt tacaacaaaa tcagaagaag cagaagatgg attctctata ccgctttgat
     7261 ttgctgtatt tggacgagat gaagcattgt tcgttccgcc attcgatgaa ccattgtttg
     7321 gatggtttgg ttctctctga gtatttccat tgttattcga tccagatggg tttgtttgat
     7381 tcgaagaatt cccgctgttc gaattattgt tattattgtt tgaattattt gaaccattat
     7441 tattgttgtt attacccaca tctggtttgt ttggcgtttc cggatctggt gtactaggga
     7501 cttcttcact aggatcagtt ggtttctctg ttgaagtatc cggtccagct ttaaattctg
     7561 cagtaataga taaattgttc gtacctactg taaaggtctt tgcatcataa tttacttctt
     7621 tggcaccatt aacagcgact gaagcaattt gttcaccttc agctggcgta atagtgtaag
     7681 ttaccttcgt ttccgctaat aaaccttcta ccgttccact ttccgtaata tccaaaggtt
     7741 gctgttcagg ggaatccgct gtcgaagcag tcagttggat cttaccaatc aaagaaggag
     7801 caattgtaag ggaatatgtc tcggctggct tttcattttc tgatggatca gccggatcaa
     7861 tttcagttgg ctcggtcgat cctgttgttg agttagttgt tccagttggg tcttctgtaa
     7921 aagaatccgt tgtttcacta gtagctgagc tggatgtagt cgtatctgtt gtgactgttt
     7981 gatcagctat ttgattatct acggcaaata cggtattggt cgacaaaaca gacggagcaa
     8041 tcagccaagt agcagctagc aaacgtatcg tttttttatt tttcataata aactagtcct
     8101 tttcctttca ttgattttct gtcttattca gcattcatta gacatttttt ggaacagata
     8161 atcgtgtcga aaagcttttt cttttcataa atctgtctgt gtattctaaa taaaacaatt
     8221 tgtaaataag caacgagcat tcattcgttt ttctttgacg ttcattttat tgcatagacc
     8281 acctttgttt ggggataaac aagtggggat aaaaatggtt atgcatatgt aaattatacc
     8341 aaagtttgga aagtatcaca aaaatttata aaaataatga tcctaaaaag aaaaagactg
     8401 aaatatgtga taaacatctc atacttcagt ctttttcatt aactattcat aagacattag
     8461 gtcttcatca aacccgctaa cgagagtagt gatcattgct acgactagac taacagccag
     8521 tcctgctaag taccagaaaa aagtaccgga aatgaatgca ggcaatgtgg tcagactacc
     8581 aaatacaaaa gcgatcgctt tcacttgggc aaatcccatt acagctccac cagcagctgc
     8641 accaatgcaa gcagcaacaa atggtttttt caatgggatc gcaattccgt aaacagttgg
     8701 ttcggtcact cccgcaagta aaatcgaagc aaaagcagaa ccggagatcg aacgggtttt
     8761 tgaacgttta cttcgcagaa atacacctaa agctgcacca gccattccaa aattggctgc
     8821 tcctgtcaac ggaacgattc ggtcgaaccc ataagcagag atattactga tcatgacagg
     8881 gtttacagcc cattggatac caaatattac caaaatattc caaccaccag cgatgattgc
     8941 gccactgatc ggtccgttaa tatccatcat ccaagtaatt gcggcagcta aaccttcgcc
     9001 aaggtaaaca cccgcaggcc cgaataccat taacgtcaaa ggaaccgtga taactaatga
     9061 aagtaaaggt acaaatacta attgcatatt ttcgcgaata tattttttga ggaatttttc
     9121 aacaaaagaa taaaagaaaa tacctaaaat cgccggcatg acagtagacg tatactgcat
     9181 cagtactaca ggaatcccca gaaaatcagt agctgctttg ccactgtctg aaagtaaaga
     9241 ggtcagattc ggttcaatca gtgctgcagc aatgacagcc gcaatatatc cattcacttt
     9301 aaacgttttg gcagcagaaa aagcaagaaa gattggcaga aaataaaaga cggcattcga
     9361 cgcagcagac aaaatatgat aagttccgct tgtttcacta agccagccaa tcgtagtcgc
     9421 taaaacaacc agacctttta atataccaga accggcaaac agcggaatga tcggcgtaaa
     9481 gatttccgat atcaaaccaa atagtttttc gatcggattt agcttttctt tcggagctga
     9541 atgatcgatt tgacgcgtca attccttgta agcaggagcc aatccctgat ccatgattat
     9601 ttctgcatat ctatcgagta aaatgaaata cttaatggaa gggatttgct gttttaattt
     9661 ttctgcattg gctactggct gttttttcaa tttgatacga agccgagtcg cacatggaag
     9721 gacagaatca atattgtctt ttcctcccaa ctgttcaatc agcatatgaa tctgctcgga
     9781 cagtaccatc tgttcaggat tcattgtcgt ttccattaga agaccactcc actcactaat
     9841 ataatattgg cgtaaggtgt catttcgcct gtacgaataa atgcatgaca gttattcaac
     9901 tcttttttca tttcttcatg tgggataaag ctaatcggtg tatctggtaa caataatttg
     9961 attttttcca atatttccgg gttcattgtc tttatttctt ccgccaattc aatcgattgt
    10021 acctcaagtt cttctaaaac gttttctaaa acagataaaa aacttggaag accgtttgag
    10081 acagccaaat ctattttttc agtaccaaag gggacaggca tgcctgcatc cccgatactt
    10141 aatttatcaa agtgccccat ttgtgcgatt actcgtgaaa tatctgaatt gattactttt
    10201 ccttttttca tgtttgtttc ttcctctcat tgttaatttt agactgctga ttgttctaaa
    10261 gcttcgcggt aagggataga aggttgcgca ccataagact gcacagcaac agaagaggct
    10321 agatttccat aaaggatcgc ttctttcaag ttactaaggt ctggctgaag tgtgctgctt
    10381 aatgcgccaa taaatgtatc acctgcggct gttgtgtcaa cggcatccac tttaaaagca
    10441 gggacgatac cgtgttcttt ttctgtatga tagaaagcgc cggcactgcc tagtgtaatg
    10501 attactgttc caatacctaa ttcatggagt ttttcggctg ctgcgaccaa actgttatga
    10561 tctgtcactc tgattcctgt aatgatttct gtttctgttt catttggtat aatgatatct
    10621 gtcttttcaa gtagttcagt aggaatcgtt tcacgagctg gtgcaggatt caggatcgtt
    10681 gtttttcctg cgtcttttgc aatagaaaaa gctaggatcg tcgcatctaa gctactttca
    10741 aactgagcaa taataaagtc actgtttgta atcagttgct tgttttttag gacttcttgt
    10801 tcatggaaag cattatttgc ccctgcatgg atcaagatac tattttctcc tgctgcgtct
    10861 accataatca ttgcttgtcc ggttgtggcg ccttggattt cagctatccc agatgtatcg
    10921 atgttttctt ttgtcagtag atctaataac tgttgtcctt cgctgtcagc cccaacgcct
    10981 ccaataaaag atgtccgtgc gcctgaacgt ttggctgcca ctgcttggtt ggcaccttta
    11041 cctccgccag cgtgaaaaat ctcatgcgca tgcatcgttt cgcctggctt gggcatgttg
    11101 gttaaacgaa gggtagtgtc catattaata cttccaatta ctgtaaccgt gttcatttta
    11161 caaacctcca actatctcat ttattttgat gggaaaatta ttttttaaaa cgttttagta
    11221 aaacgtttta atagttcgat aaaaatatag cacaccttga aagctatttc aagggtgcag
    11281 ttgaaaatct tttttctaat cgtacaggta atcttttttc ttcccattct ttttctggga
    11341 attggatccg atctaacaat aacttggcag atgtttgtcc caattcgaag attggttgtg
    11401 cgatcgttgt cagtttcggc ttgatatact cgcacatatc tatattatca tagccaataa
    11461 tgctgtagtc ttcagggatg ctttttccag cttcctctaa tccgcgatat aatccaaaag
    11521 ctaattcatc atttaaagca aacacaccag ttgcagcaga atcaagaagt tctgctgtga
    11581 tctggtagcc accttgtttt gagaactgtg taggtaagag gatcagttgg tcgtgaggga
    11641 tttggtaaac atcaagagca gatttaaacc cctcaatccg agcgtggaca ttttccggtg
    11701 gattttcagg atagacaagg gcgatcgttt gatgtcctag actaagcaag tgcatgcccg
    11761 ctaggtaacc accgcgaaaa tcgtctgttc gtacggcatc actaaatcct tcagattttt
    11821 tctgatccaa aacaatgaag ggccggcctt gttttttcaa attttcgttg attgcatctg
    11881 tagagacagc agaagtcgcg ataatgaatc catccacacc tcgacgtgtg agctcggcta
    11941 gatattcgat ttctttttga tgatcagaat cagcattaca taatatcgtg acgaaattct
    12001 gcttatacaa gatatcctca attcctcgca tcagtgtact gaagaatgga ttcgtgatat
    12061 caggaacgag tacaccaatt gttttcgttt ccttggtaat catttgtcta gcaaaatagt
    12121 caggctgata gcctaattct tctttggcag ctaaaacttt ctgaacagtt ttcggactga
    12181 atttctccgt atttccattt aatatcaagg agacagttgt gattgaaacg ccggaaagtt
    12241 tagcgacttc tttgattgtg atcttttttt tcaccatgtt catactccta tctaaatcct
    12301 gtggttattt tcccatgaaa tcaaaaagaa gtaaatgaaa atcacgtgtg ccagtactta
    12361 tttgctttgt tggatagctt cgattatttg tttcgttgag cgtactcgtg cagttttcgg
    12421 aaatatcttt tttatgaaca attgatggga ttctttgtca cgatcactgc aagcatcttc
    12481 agcaagcacg atatggtacc cgtgttgaaa ggcatctaat gcagtagcat atacaccgtt
    12541 tgttgtcgct acaccgctta aaatgatagt ttcgattcca cgccggcgaa gttgaagatc
    12601 aagagaagta ccaaaaaaag cacttggatt gtattttgtg atagtcaaca tattatctgt
    12661 atctttcaaa gaatccttca aaagtaaatc agtgaattct ggaggtacag aagcagtcat
    12721 tccacccata tcagtttgtt gactcaaata agggaaagtg gagatgtcta cgttcactaa
    12781 aactttcaag gcagcggtac gtttcaatgt tcttactaac aaatcattgt ttgtcagaat
    12841 agatgctgca gtgtgtggag agagtgtacc gttatttacg atctcttttt gcatgtcgat
    12901 cgcgacaaaa gcagtttttg ataaatcaaa aatcatattt tcctttaaat cattcatgat
    12961 gttccttctt tcaaataaca atgtttttta tgtaagtaaa tcataaatcg tttatttgtc
    13021 aactaaatta aaggattcct ttctttagtc tagagaaatt cagtggtaaa ataaataagt
    13081 gtgagaaaac gcattcgatg catagatata gcgagaaata tcgtgaaaat ggaggaatca
    13141 gagtgaagta tgtcgaagta aaaaatgaat acaaacgata caaaatggga gaaacgacca
    13201 ttacagcaaa tgacgatatt tctttttcaa ttgaaaaagg cgaattagtg attatacttg
    13261 gtccaagtgg agcaggaaag tcaacgattc ttaatatttt aggtgggatg gatacacctg
    13321 atgaaggtca gatcattatt gatgacacag atattgcgca attttcagat aaacagctta
    13381 ctgcttaccg acgaacagat gtagggttcg ttttccaatt ctacaatctc gttcctaatc
    13441 taacagcaaa agaaaatgtg gaattggcaa cggaagtttc tcctgatgcg cttgatcctg
    13501 tagaggtatt gaggcaagtg ggcctagctc atcgattgaa taactttccg tcccaattat
    13561 caggaggcga acagcagagg gtttcaattg ctcgtgcact agctaaaaat cccaaacttc
    13621 ttttatgtga tgaaccgaca ggcgcgctgg attttgaaac gggcaagcaa gtattgaaat
    13681 tattgcaaaa cgctagcaga caacacggca ataccgtttt gatcattaca cataattctg
    13741 ctttagcgcc catcgctgat agagtcattc acattaatga tgctaaagta aggtctgttg
    13801 aattaaatga tcatccttca tccattgatg agattgtatg gtagggggat tttatgaaaa
    13861 caagaacata tcttaaagca ggttttcgcg aaattcggca atctaaagga cgattcattg
    13921 caatcatcct tattgtcatg ctaggaacac ttttatttgt aggtgtcaaa actgctggac
    13981 ctgtcatgca aaaaacgatg gatcactatg ttggtacagc aggactttct gatttgcaaa
    14041 tcgtttctac tggtggcttg acacaaaaag atattgctca agcagaaaag atcccagatg
    14101 caaaagtaga aacaggaaaa cagatctatt attccaatac tggcaaaaac gaagtgattc
    14161 aaatattttc ttataacaaa aataacaagc agaacaagct acaattaact gatggaaaac
    14221 tcccggaaaa accaaaccag cttgtattgg atgaaaaagc ggaagatgaa gggtataaaa
    14281 tcggtgatat ttatcagatt gattcagatg aattgaaaga aaaagagtat accatcacgg
    14341 gctttgtccg ttctccattg ttcatcaaca atttggagag aggatacgcg aacgtcggaa
    14401 atggtagcgt cgattatttt gtctatttac ctgaatccgt ttttaaaaca gatatttatt
    14461 ctgtcttata tcttgatttt acaaacgtaa agaatttgaa tacgtacagc aaagcttaca
    14521 aagataaaat ggagcaaaat caagaaaagg cagaaaagta tttacaagat cgacccgaag
    14581 aacgcttaga agagctgaaa aaatcggcca acgaagaatt agaaccggca cagcaaaaaa
    14641 tagcggatgg caaagcacaa acaacgcaag caagaacacg gttagaagat gctaaaaaac
    14701 agttagcgca acagtcagca actatccagc agcttcctga agcgcaacga acaatcgctg
    14761 ttcaaacatt atctcaacaa gaagctcaac ttgctgaaca agaaaggcaa ttagttgaga
    14821 aagaacgtga actggcctct gcagaggaag aattgaatcg aaatgcagaa aaaattgaaa
    14881 atttaactaa accatcatac ctatacaatg aacgttcaga aaatgtcggt tttcaagaat
    14941 ttggtgatct gtctgatcgt atcgctgcga ttgccaatgt ttttcctgtt ttctttttct
    15001 ttattgccgc attgatcacc tttacgacaa tgacacgtat ggtagaagaa aaccgcaggg
    15061 aaatcgggac attaaaggcg ttaggttata cgaaagttga aatcgcaaaa aaatatgcaa
    15121 tctatgcaag tctagcctca gggataggta ttgttttagg aacgatatta ggaacgaatc
    15181 ttttgccaag gatcattttt gagctgtcta acgagcggta tgatattggg agtgcgctta
    15241 ttttttatga ctggccgccg attttacaag cagctgccgc attcttcatt gccgcatttg
    15301 gcgctgcaat gatcgtttta ttcaaagatt taagagaacg gcctgctgca ttgcttcaac
    15361 cgaaagcacc gaagccaggg aaacgcattt ttcttgaata catcactccg ctgtggtcac
    15421 gccttagctt taatcaaaaa atcagttacc gaaatctctt ccgatataag tcaagaatgc
    15481 ttatggcgat tatcggaatt gctggatgtg ccgggctgat ggttgcaggc gtgggattga
    15541 aagattctct aagttctgtt tcagccaaac aatttggacc gatcattgac tatcaagcaa
    15601 tcgttacatt ggattcatcc acggaagata gtcgtcaaaa agcagcggat atgctgcaga
    15661 agcaagaaaa agtaaatgag atcctagcta ttcatactca aaccgtagaa ttgagaaaaa
    15721 aaggacatgc ttcgcaaagt ctgacagtga tcgtaccaag taaaacagct gatttggatc
    15781 gttttatcca tttaactgat cttgaagaga acccacgctc cttgcctaaa acaggaatcg
    15841 ctattacgca aaaagtagca gaactatttg acttatctac aggagatcat atttcgcttt
    15901 atgatgaaga tcaaaaagaa tggaaagtcg aagtaaaaga aatcgtgaaa aactatctag
    15961 gtagctttat ttatatgtcc cctgaatatt atgcttcagt tactgatcaa tcgatgatgg
    16021 ataatgcatt tttgctgcgt acagataaga tgacaacaaa agaagaagaa atgctttccg
    16081 agaaactgct tgccacagac gctgtgacaa atacgtcttt catgtccaaa caaatcgaaa
    16141 cgcaagaaga atcaatggcg aacttagact cggttgtctt aatctttgtc gtattatcag
    16201 gactgctggc ttttatcgtc ttgtataatc taactaatat caatatttcc gagcgtgtac
    16261 gcgaattatc tacaataaaa gtccttggat tttttgataa agaagtcacg atgtacattg
    16321 ttcgagaaaa tatcatcttt actcttttag gaatcatcgg aggatttggt gtaggatata
    16381 tattgactga cttcatcttg caacaagcgt ctatggagaa tgtcatcttt ccattagtga
    16441 tcacatggtg ggcttatgtc ttatcagcag gattaactat cgtatttacg gttattgtga
    16501 tgattgttac ccatttcaaa ttaaagcata tcgatatgat tgatgcgttg aaatcgaatg
    16561 aataaaaaca gaggttgtga aatcagcggt ttgacctgag tattagagaa acaaacggca
    16621 aaatagtttt tcatattttg ccgttttttg agctaatacc gaaggacagc tgattgaaca
    16681 ccatgaatca gaggttgtaa aaaagccgtc ctgcatcgag caaaaagaat actcaaataa
    16741 aattagctcc tcatgtttta catttgagaa gactgattgc cgtagataaa agcttttgaa
    16801 caccatttat agaagaaaca agaatatttt gctattttaa acaagaggat agacaaatac
    16861 atgtctgatc tcttgttttt tattgggcaa cagacctctt agaatgtata aagataaatt
    16921 ttacaaacgc tttcggttca gttataataa taaatgataa cttgtatata taagttgtgg
    16981 taggtaataa atcagttgaa tggaggtaaa tatccatgac atttaaagac aaagtcattt
    17041 accaaatcta tcccaaatct tacaaagaca gtaatggtga tggaattgga gatttaaaag
    17101 gaatcaaaga aaaactcccg tatctgaatg atctaggcat cgacatgatt tggctaaacc
    17161 ctatttatcc aagccctcaa aaagacaacg gttatgatat ctctgattac acagccatcg
    17221 atcctatctt tggtacgatg gaggaattcg aacagctaat agccgaagca aagaaatacc
    17281 ggatagaaat catgctcgat atggtgctga atcacgtttc gacagaacat gaatggttca
    17341 aaaaagcact agcaggggac cagcattatc aggacttctt cattttaaga gaagagccaa
    17401 cggattgggt atcaaaattt ggtggaagtg cttggtcgcc atttggagat acggggaaat
    17461 attatttgca cttatatgat cggacacaag ctgacttgaa ctggcggaac caagcagtaa
    17521 gagaggaact attcaaagtt gttcgttttt ggatggaaaa aggggtaaaa ggattccgtt
    17581 tcgatgttat caatgttatc ggtaaagacg aacaattgaa aaataataaa gaaaatgatg
    17641 gcaaacctga atatacggac aaaccaatca cccatacgta tctaaaagaa ttgaaccaag
    17701 caacgtttgg gacggattcc actatcatca cagtcggtga aatgagctct acgacgatcg
    17761 aaaattgtat cttgtataca gaacctagta gagaagaatt atcaatggtc tttaatttcc
    17821 atcatttgaa agtcgattat gaaaatggga ataaatggtc tactcctcca tttgattttg
    17881 cagaattaaa gcgactattt catacatggg gagaaaagat gagtgagggt aacggctgga
    17941 atgctctatt ttttaataat catgatcagc cacgtgcgct caatcgattt gtagctatcg
    18001 atcagtatcg aaaacaagga gcagagatgc tagcaaccat gatccatttg aaccgtggga
    18061 cgccctatat ttatatggga gaagaaatcg gcatgatcga cccagactat tcatcgattt
    18121 ccgactatat tgacgtagaa agtttgaatg cttataagtt actccttgaa caaggattca
    18181 cagaaaaaga agcgtttcgt cggatcaaag caaaatctcg cgataactct cgaacaccca
    18241 tgcaatggtc agacacagaa caagcaggat ttactacagg gaaaccttgg ttaaaagttg
    18301 gaggcaagct agaagagatt aatgtagaaa aagaactatc ttctgaagat tctattttgt
    18361 cctattacaa gaaattgatt cggctgagaa aaacatatcc aatcgttgca caaggagatt
    18421 atcatgctta tgaagcaaat catccggaag tttatggctt tcttcgccaa tttgaaggac
    18481 agcagctgct tgtattaaca aatttctatg ataaagatac aaggatcgcc atcccagaag
    18541 gattcacaga agccaatatt cttatcgata attattccga tactgttctt catcaaagtc
    18601 tggagctaaa accataccag gcaattgctt tgctgaaaaa ttaaaacaaa aacacaaaac
    18661 gtcgttccta cgagctattc tcgtaagatc gacgttttgt gttttattta aaataatctt
    18721 cttcagaaaa tgaagagttt tcatactctc ctttatcgcc ataaaattta ttgtagcgtt
    18781 gtttgaattt acggaaaata aaagtaacga gtaatttgac taacgtatag ataggaatac
    18841 caaaaataac gcccacaatt cccattagat cacccatgac aagtaaaacg attaagatcg
    18901 taatcggatg gatctgtaaa cgatcaccca ttactcgagg aatcaccaag tcaccgtgga
    18961 gaagttgtac ggcaaaccag acaatgacaa atttgacagc cataaaagta gagtcttgga
    19021 atgcaatgat caaacctgga aagaaggcga taaacggccc aatatatgga atgatacata
    19081 acaacccagc agaaatagct aaaacactag caaattctaa tccgatcagt aagaaacaaa
    19141 cccagtagac tgctccaagg ataaatgaag caatgatttg cccctttaga aatgaaccca
    19201 attgttgatt agcaatcttt gtcaaatttt taaaatctgt acgaaatgct ggtgggacaa
    19261 tcgctaaaac tgactgataa aatttttgag gatctctcaa aaggaaaaaa gcgacaattg
    19321 gaccagtaaa taaagtaata aaaatagctg taacagttga aaaaatgttg ctgatccgtt
    19381 gtgcgccact ttcccaataa tttccaataa atccagctat atcagacgtc acgtcgtcaa
    19441 tagaagcgaa aaattgatta aatgaatcgg caaaaggtgt tttctccaaa aattgtcgga
    19501 gactctcttg aaaatcttga aacaaatctg gcaaactact gatcaatgtc tttgcctgtt
    19561 cttcaagaaa aggaataagc catatgcttc caagccccaa taaaaataaa ataatcacat
    19621 aaacgataat gactgacaag ttcctcgaaa ggtgcttgct caaacgtttg atgactggtt
    19681 ccaaaagata atacaagatc agtgcaaaca ataatggggg caagatagta gcgataatga
    19741 ttccgacagg cttgaatata aacgagatct gatggaaaaa ataaatgatc agcgcaagta
    19801 agataactat tcctaaaaca tagtaagagg tttttcctcc taaaaagcgg atcaaacgat
    19861 tcgttgtatc tgtttctttt ttcactcttt ttcctccttt atctataaat tcattataga
    19921 caaaagcggg tataaaagga aaatgataga ggttgattgc aaaaatatcg tcaatcattc
    19981 atataaactt tctcatcaat taaaataaga aaacgcttga cagttctttt aaccatatga
    20041 taaattaaat cctgttgcta aaacgtaact attacggttt gcgaaaagcg aatcggaaca
    20101 ttcaaatgaa agaagatgag aagaggagtg tcataaatga aacgattgat aggtatattg
    20161 gccatgctgg ttttagcagg tatgttaact gcttgcgggg caagtgggaa agccgaggac
    20221 agtaaagaaa aattgagcgt gatgacgacc ttttatccca tgtatgattt tacaaaagca
    20281 atcgtcgggg atgaaggaga agtagagtta ttgattccag cagggactga ttcccacgat
    20341 tatgaacctt ctgctaaaga catggcaaag atccaagata cagatatctt tgtttataat
    20401 gatgaaaaca tggaaacatg ggtccccgca atccaaaaaa cattacaaga aggcaatgtc
    20461 catacgataa aagcgacaga aggtatgctt ttacttccgg gaagtgaaga aggacatgat
    20521 catgaccatg aacacgggga agaaggccat acacatgagc tagacccaca tgtatggcta
    20581 gctccaagtt tagcaatcaa gcaggtagca aacatacgtg atcagctgat tgaagcttac
    20641 ccagaaaaac aggaagtatg gacaaaaaat gcagcagcct ataccgagaa acttcaagca
    20701 ctccatcagc tttatcaaga aacctttaag caagcaaaac aaagatcttt tgtcacgcaa
    20761 catgctgcat tcaactatct agcgttagaa tatggattga atcaagtatc gattgctggt
    20821 ctttcttcta gtgaagaacc gtctgcggcg agaattgctg aactgaaaca ctttgttaaa
    20881 gaacatggaa tcaactatat ttattttgaa gaaaacgcca aagatagtat tgccagaacg
    20941 ttagcaaacg aagcaggtgt atctttagaa gtattgaatc ctttggaagg attgacgaat
    21001 gaacaaatag aaaatggaga aaactatctt tctatcatgg aagcaaacct cgaagcgttg
    21061 aaaaaaacga cagagacaga aaacccgcta gaagatactt tgacccccaa aaaagaaaag
    21121 agcgtctaca acggttattt tgaagacgag gatgtacaag atcgctctct ttcagattgg
    21181 gcaggaactt ggcaaacagt agatacgtat gtagaagatg ggacttttga tcctgttttt
    21241 gaatataaag aaaaattgaa tcaggataag acagcacaag aatataaaga atattatacg
    21301 aagggctatc aaacagatat tgcttcaatc aagatcagtg agaaagagat ggcatttacg
    21361 tttaagaatg gaacaacgaa acgttcaaat tatcgttatg tagggaaaga aatcttgacc
    21421 tacgaggcag gaaaccgtgg cgtaaggtat ctattcgaag cagaagataa ggaaagtggc
    21481 gcttttagat atattcaatt cagtgatcac acgattgcac cggctgactc cgaacatttt
    21541 catttatatg caggaaatga aagtcaagaa gtattgctga aagaaatgga gaattggcca
    21601 acattttatc cagatacaat ggatggacgt gaaattgcac aggaaatgct tttgcactga
    21661 taggcaaaaa agaaccgaag ggtttggatc ggctggtcat ttagtcggtc caaactattc
    21721 ggttcttttt atgaaatcaa tttctttaat ccacggatag aggctgggat ggtctcgccg
    21781 tttgccaacg tgacttctct ggttttttta ttaatcgacc gcacattttg tgtattgata
    21841 acataggatt tatgacaacg gataaaattc cgatgcattt tctcgatttc tttgatcttc
    21901 tcatagaatt gtaattgggc atgagtcaaa tggacttcca gtttatgtgg cgctcctagc
    21961 gaagtagaaa aatattggat gtctttgatc ggtaaaaatt tgatctcatc attaaactct
    22021 attttgaaga tatctttttg gatttgggac atttgaaaat cttcgaaaat tttgctcagg
    22081 atatgctcga cattttcttt taaatcataa agatcttctt tgacgatata atcagtcggt
    22141 tcgatgttgc tttttaagat tttcatcgac atttccgtat gggaagtcac atagattatt
    22201 tttcctaaag gatctaattc acggatcaat ttaccgatcg ctacaccatc catttcactg
    22261 tcttctagtt cgatatctaa aaagtaaata ccaaaagaag aagttctgat cttggctgca
    22321 ttgagaagtt cttccggatc agaggtagaa atatggacat aactgtctaa gttttcaatc
    22381 atgattctat ttttgatcac cgttgataaa acttctaatt gttttggatc gtcttcacaa
    22441 atataaatgg gaatcatatc attactcctt tattttattt gtatataaat cgtttgagaa
    22501 aaacgctggt tttcaattga tgtttcaagg aaaagataag gattggtctt tgtcaattca
    22561 tccaagataa acaagccaag gccttcgttt tttggatttg tttttgttga gaaccctttt
    22621 tgtttcaact ggtttaacgg taatgtattt gttgttgtat tgatcacacg aatcatcacg
    22681 gaatgattct tcttgagtat ggtcaattcg atttttttct tctttgcagc actagctcct
    22741 tcaatcgcat tgtccaagat aataccaagc atacgtacaa ggtttaccgt atgtttcgta
    22801 tccagttcga ttggctcagg aaaatgaagc tggacgatca accctttttc ctgtgccatc
    22861 atgagtttta atgacagtaa actacggatc tcaggaactt tcatattatc caacatactt
    22921 agattggccg gaaaaaggtt catcatctgg cgtgtaggta atatcgtttg atcataataa
    22981 gaccgtaatc cttctaagtc gccttctgaa atatagctgt gaagagaaaa aagcagattt
    23041 tggtaatcat gtttgaattc tctcaagtct tgatagtttt tttctagatc tttgatataa
    23101 tcctgttgca tcctgacttg ttgctctaat aactgatcag ctaatttctt attagagatt
    23161 ttccaataat aaaccaagat gatcaggcca acacacagat atagaatgaa aaaactcgta
    23221 ttcaaagcta agacatcagg tgtttcacca gaaaaacggg tataaaaaat aatgatatag
    23281 tatgtaaata atatcaatgt cccgatcgta ccgatcatac ggcggtccac agtgtgaaac
    23341 caagtctcta acgatttttt taaacaaaaa gctaataaag cagataaaaa agcggataag
    23401 acaatgtgaa aatactgcaa tgaatctcct ggttcaataa ccgaagattt caaaacaaaa
    23461 aaatcgccga tgcttgttaa gtgatctcct aaaagcgacg tcaataaccc aaaaggaagc
    23521 gcgtaaacca attgttgacg cgaagtcgaa aagaagaaaa aagtaagcat cagcattcct
    23581 atagcaatta gagcagtaaa aatccctaaa atcgaataga cccatccaat caaaatacaa
    23641 gaaatcagaa tgactcccgc aaacagatat ttgtatcgga tgtgatggtc aatcaataag
    23701 atacaaattg tgtaaatcaa atattgcaac gctatggacc ataaaaacat aaagtacagc
    23761 tcccattgat ttttaccaaa ttatagcaca attggcgtat tattttttta atttttcagg
    23821 gattttgaat tcagaactca taccaaagca gcagccagat acaaaaaagt cagataagtt
    23881 agttaattgt ttaatgattg tttttttcat gaaagattcc tccaaaattc atcaagtagt
    23941 ttgtaatagg aagcaacgta gctatttcta aaacaatccc aagtagcaaa taggtagaaa
    24001 agtaagaagc tgagaaaaat aacgtaatga gagaaaaaat tagaaacatg ctgatcgcct
    24061 tctttaataa tgggggacgt ttctcgggtt caatgggatt gattgctgta cctcttgatc
    24121 catagcgaag cagtaacaaa aagcagctga ttaacaaaaa gaccatcatt gggaaggaga
    24181 tagtcaattg cagatgtttc atcaccaagg gaacgcccca taaataaagt agtgtccaca
    24241 gcagacaaac gaattcagag tcggaatgca atccataagc atatctgcgg atgcagatat
    24301 aagaaagaaa ggtgattcct gtttccgccc atgagcctgt caccagagaa aagactagaa
    24361 cgaccgctag ttttccaaga ttattcaata aaacttctaa gacaaatttt acttggacat
    24421 acaccatatc ttcttccgat ttgtctccgc tgaataaggc ttctaataat ttgttcacaa
    24481 ctttatcttt catctcatac gtacctccac cacaaatttt atgctaaaaa aaataaaaaa
    24541 cgtcttttgt ttcataaaaa gtggttttga catcaaaacc gtcatgatct cctaaaaaaa
    24601 tcttcgtttt ccaagaacct taccaaaaaa agtgacagtt ttgatacgaa aagtactttt
    24661 tatgacaagt ttgtgctttt tcgagtgatt tatgttaaaa aattactgac cttataaaag
    24721 gtgatggagg gattcttatg gaaaatgaac aattgtttga agtcggcgaa acatatgcat
    24781 ttaaatctga tttatttgaa tcaccaataa aaggaaaaat agaaaaaatc tatgaaaata
    24841 gtgtgatgat acgtgtcatg aaatgcgcag tagaagacaa tgataccgct cataatctgc
    24901 actggcagtt agttgtacgc aaatcaagta caatagaaga ataaaaacag ataaaatgtt
    24961 gagagcataa agaggttgtg agtctcccgt ttagctctga gttacaagga ataatgttaa
    25021 aaaacagctt ttcatgtttt atgaatattg ccttgtgacc gaggtgttgg caggagaata
    25081 ctgtttattt gaaaaaaggg ctgcgacaag acttttgtca cagcctttat tttcatgaat
    25141 aggagttact tttggctact tttagagaag tagcttttaa ggagcagata aagtcaaggc
    25201 ttttatttct ataaatgaag tagtaaaatg aagaacagat tttattacag gaaggatgcc
    25261 gataattgtg atcattgttg caggaacgat cggtgcaggg aaaagcacac taactgaaat
    25321 gcttgcccaa gatttagaaa caaaaccttt ttatgagaac gtggaagata atgaagtatt
    25381 gccgctattt tattctaatc cagaaaagta tactttttta ttacagattt tctttttgaa
    25441 caaacgcttt ttggcaatca aagatgcttt cagccatgat gacaacgtac tagaccgctc
    25501 catctacgaa gatagtatgc tgtttcattt gaatgcagat ttagggcgtg tttctgaagt
    25561 agaagtaaag cagtatgaag gtcttttaga aacgatgctg aaggagttag aagaaatttc
    25621 gccacaaaag aaaccagatc tactggttta tattcgtgta tcctttgaaa ctatgttagc
    25681 gagaatcaaa aaaagaggcc gggaatatga acagctagaa caagatcctg aactctattc
    25741 ctactataaa gaactcaatc gacgatacga agagtggtat gaacagtttg atatatgtcc
    25801 caaaatagtg atcgatgggg acaaatatga tttcgtagcc gatccggcat gtggagaaca
    25861 aatcgtacaa gaaatcaaga tgcgggcaaa gaaaatgaca gaagaggcag atgcccagtc
    25921 gatccgctac actacaaata acccgaaagc aaagggaatc tttacaacta aataatataa
    25981 aaactaagca aattgctcac tcgcagatat ttctctgtga gcagcatctt gcttagtttt
    26041 tttgattcat tgagatcaaa tagtgaaccg attcgtatga taaaattgcc ataaatgaaa
    26101 tgtctgagtg agggccatga tcaaaaataa aatggaaacg atcaaaatcg aatgggcgcc
    26161 aaacagatga tgacagaaaa caaggacaat agctcctgcg ataaaggcaa gaacgacact
    26221 tagatagtgg aaaaatcgat caaaatctgc tttttcttta gaaatacaat aatcatataa
    26281 gttcgttgct acccctttta aatttccagt tgtaaataaa ttagtgtagg cacgcccgtt
    26341 gattttatca aaagctaccc actggatcga tgcagtaaaa gcaatcaaaa tcgttactaa
    26401 tgcgggatgc tcatggacgg gtgtcaaact aacaaagaaa aaaatcactg cttcataata
    26461 tagaacaaac aagcgccaga aatgtttttc tttttttcta aaataatcaa ttagatactt
    26521 tgttagaaga atccctaaga aaaagaaaag ggtagacaat acttttttac caacacttag
    26581 ccattctccg tcaaatgctt ggatgatcga tagaatgata ttgccagttt gagcagaggc
    26641 aaaagcacca tattggatat aagtataact gtccatggct cctccgataa atgtcagcaa
    26701 aagtcctatt gtacgcccct cgtgaaagga agtctgcatt tttttcatca ccttttatga
    26761 atatttttgt cttccttatc ttagcataaa cgattgaaaa aaaggaaaaa ttttcagaaa
    26821 actaaaatca tatcgcttcc cattttcatt tttagaaagg tctgttagta taaagaaaaa
    26881 atagacaacg aaactttaaa taaccaactt gaaataaaca aattcaaaga agaaagatgg
    26941 gaaggaaatc aatcagttga atgaaaaaga aattctccga ttacaaaaag aattgaaacg
    27001 ctgggagaac aagtataaaa agcttcaaca agtctttcgg ctacaagaag aaatcattgc
    27061 tacctatgaa gcggcttatg gcgaagcacc cggacttatt gaggaagaag tacaagtaaa
    27121 agaaagtgaa ggaaacagct ctttctttaa aatgatggag aaacgttcct ataatcgctt
    27181 caatcaagaa caaaaagcag ctatcacata tgatatgaag aaacatcttc gaatcatagc
    27241 aggagctggg agcggcaaaa cgcaaacaat ctgtgcaaaa gctgtttatc tgatgacgca
    27301 aaaacaagta gacgaagaac gcatactaat gatcactttt acaaggaacg ctgcaaatga
    27361 actaaaaaaa cgagtagata atttcagcca gagaaaaacc gctgtccata tcggaacatt
    27421 ccatagtatc ttttttagga tatacaatga aatttgtcga aaatttcctg aagtagcaat
    27481 gcaaggaata caaggagact tttcaaagga tactgcacaa aaagtgaatg ctgttttgca
    27541 acagctgata cgtaaatata atctttatat atttgatcaa tatggagaaa aaacgattgc
    27601 ttctcggtta gactattggc agaatatgaa cctttcagta gaagaaatgg ttcagttagt
    27661 taaagaaaaa tatgattcca ttgataagaa tgcacgacag ccgatatcag aacgactgta
    27721 tggattgctc acggaactcc aagaacaaaa aagaagccag caattgctag agttcaatga
    27781 tgtactccaa aatctgaaaa gcgctttgga gaatgaggag atccagcatt atatcggcca
    27841 aaaatatgat tatctattca ttgatgaatt tcaagatact aatccacttc aatgggaaat
    27901 cgtgaaacgg atgacaaagg aaaacaggat caagttgatt gttgttggag atgatgatca
    27961 gagtatctat ggattcagag gatcagagcc agcatacatc aagaactttg aaaaagaata
    28021 tcctaccaaa actcttttct tattaactaa ttatcgttct cgggcagcta ttgtccaagg
    28081 agcaaataga ttgatcagct ataataaaaa tgatcggata ccaaaggcga tgattccagc
    28141 acaaaaagaa gcaggtgtta tggaagccta tttgttttct gatactaaag cagaaagtca
    28201 gtggctaatc aaacaaattc agacatttat tcaaaaaaat gggaaatata aggaatcaat
    28261 catattatac cgatcagctt cacaaacgca gcagcttgtc caatctctgc tgaaaacgaa
    28321 tattcctttt gtactggaag cagatagtcc atatgaaggt atctttggta tcaagtcttt
    28381 ccaacatttc tatcaaaaaa ttgttcattg gcaaacagca ctgaatctgc aaaagaaaaa
    28441 tcaggcctac cagcaattgc tccggcagct gatggcagac tgctacctga aaaaaagtga
    28501 atgcgatcaa tacttttctc ctaaatatca aaatatagcc gttgcagatt atattttgtc
    28561 gataagcccc aatttaaaat cgaaatctgc agaaatccga gagtttgagg aagcgttgcg
    28621 taaaacagac cagcatcaag aaatctattc gcttgttcaa agctatcttc atctgccacg
    28681 tatagctaag gaaatcgacc agagtgatca agaatggata cgagaagaag taaagcagca
    28741 tgctactttc agaagactcc aagccttatc gcaagaaacc caagcgacag ctaaagaatt
    28801 aaaaacccgc ttgattgctt acagacaagg aaaacttgat gcactatgta tccagagcat
    28861 tcacaaaagt aaaggtctta gttaccgaaa tgtctttttg attggttgta acgaaggaag
    28921 tttgccttat aacggagcga cagaaaagaa agtaatcgac tttaatgaaa taaaagcaga
    28981 accagtaacg acgatagaag aagaacgaag actattttat gttgcgatga ctagagcaag
    29041 aaatcgtctg tatctatgtg tacctcaaat gaaaaattca agaaaattga aagtatcgag
    29101 atttatcaaa gaaaccggga gtcgtgtgaa aaaaggaaag tgatagaaga gagggtgtga
    29161 cagaagtggt cagtttcaag aaagaagaag gaatgtacga aaattgcttc tcaaattttt
    29221 gtgaaatttc agcttatttt cgaagaagct atttctggaa cacagtttat tcggaaaagg
    29281 gaggtgtgac aagaattttg tcacacctcc cttatttatt ttgaaaatga gaatactatt
    29341 atcaaaatag agaatatata gaaaaattct cattattcaa acgtaaataa tcagttattt
    29401 tgattttttt tatattttat tagctaataa ttggtatttt aaaagaaatt actgtagaat
    29461 tggattataa ttaaaaagga gtgagaaaat gataaaagta tatacttcgc ctagctgtac
    29521 ttcctgtaga aaagcaagag catggttgca agcgaatcaa cttgaatttg aagagaagaa
    29581 tatttttgcc gaaccgttaa cagaaagtga gatcaaaaag atcttggcag cgactgaagg
    29641 aggagttcaa gatattattt ccactcggtc gaaaatttac gaaaagctgg gcatagattt
    29701 taacgaatta actttaaagc aaatgatcgt cttattcaaa gaatatcctt cattattgag
    29761 acgacctatt ttgattgatg aaaaaagaat actaatcgga tttaatgaag atgagatccg
    29821 gtcatttgtc cctcgtgaaa ttcgatgtgt tgccagaaat ctgatctatt tacaaaacaa
    29881 taacatctta aattcatagg gagggagcct tcgtggaagt gaaagtctat ggatcagcgc
    29941 actgtgtaac aagtctgaag gcgaaacaat ggttagaaca ccatcaattg ccttatcaat
    30001 ttgttgactt agaagaacgc gatctaagta cagaagaagc agaagaatta tgcagttttg
    30061 aagaagtgca agcagaacag ctatttgcga cttggtctga ggcttttcac aacattgcga
    30121 ttgacctttc ctgtgtagga aaaaaacaac tgattttttt atgcacacaa cataccaatc
    30181 tcctcagacg tcctttgatt attatcgatg aagttctatt tattggatac aatgagcagt
    30241 tgatggaaca gcttatctta aataaataga ctttaactgt tttaatcaag tcactgagca
    30301 tttcatacag ttgtaacagt cgaacactta gcatcaagcg tgttatgtgt tctttttttg
    30361 actttatttt tctactatag agacatgctc aatttatgtg gtcaaaattc aaatctaggt
    30421 ggggatatag agttaaaaat atattgacat gtgtaaattt acatgatata ttcatttctg
    30481 ttgttttaag tagcaaagca ataaaatagt attttaaaaa acatataaaa tagttgttga
    30541 catgttagaa atgacatgat aagataactg agttgttaaa aaagaaccac ttgtgaagct
    30601 tgattctatc gaaaaaaact tcaaaaaagt tcttgacaaa taacaaatga taagttatga
    30661 taaatgagtt gctgtaagat ttcgaaaaac gaaatcaaaa aaacttttaa aaaagagttg
    30721 acaattactt gtctctctga tatgatataa aagttgctac ggcagccaaa aacgaatcgg
    30781 g
//
LOCUS       DADQCX010000028        30734 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.028, whole genome shotgun sequence.
ACCESSION   DADQCX010000028 DADQCX010000000
VERSION     DADQCX010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.028"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(84..1667)
                     /locus_tag="J8R83_001169"
     CDS             complement(84..1667)
                     /locus_tag="J8R83_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9574307.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(2245..2388)
                     /locus_tag="J8R83_001170"
     CDS             complement(2245..2388)
                     /locus_tag="J8R83_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAZ9574308.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(2610..3089)
                     /locus_tag="J8R83_001171"
     CDS             complement(2610..3089)
                     /locus_tag="J8R83_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9574309.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(3162..3446)
                     /locus_tag="J8R83_001172"
     CDS             complement(3162..3446)
                     /locus_tag="J8R83_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574310.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(3524..3718)
                     /gene="ssrS"
                     /locus_tag="J8R83_001173"
     ncRNA           complement(3524..3718)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="J8R83_001173"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(3790..5076)
                     /locus_tag="J8R83_001174"
     CDS             complement(3790..5076)
                     /locus_tag="J8R83_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAZ9574311.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            5214..5885
                     /locus_tag="J8R83_001175"
     CDS             5214..5885
                     /locus_tag="J8R83_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAZ9574312.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            5851..6339
                     /locus_tag="J8R83_001176"
     CDS             5851..6339
                     /locus_tag="J8R83_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAZ9574313.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            6352..7299
                     /gene="prmA"
                     /locus_tag="J8R83_001177"
     CDS             6352..7299
                     /gene="prmA"
                     /locus_tag="J8R83_001177"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAZ9574314.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            7300..8064
                     /locus_tag="J8R83_001178"
     CDS             7300..8064
                     /locus_tag="J8R83_001178"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAZ9574315.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            8297..10510
                     /locus_tag="J8R83_001179"
     CDS             8297..10510
                     /locus_tag="J8R83_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAZ9574316.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            10521..10967
                     /locus_tag="J8R83_001180"
     CDS             10521..10967
                     /locus_tag="J8R83_001180"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAZ9574317.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            11138..12397
                     /locus_tag="J8R83_001181"
     CDS             11138..12397
                     /locus_tag="J8R83_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAZ9574318.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(12486..13433)
                     /locus_tag="J8R83_001182"
     CDS             complement(12486..13433)
                     /locus_tag="J8R83_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAZ9574319.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            13827..15119
                     /locus_tag="J8R83_001183"
     CDS             13827..15119
                     /locus_tag="J8R83_001183"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAZ9574320.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            15134..16903
                     /gene="aspS"
                     /locus_tag="J8R83_001184"
     CDS             15134..16903
                     /gene="aspS"
                     /locus_tag="J8R83_001184"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAZ9574321.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            17012..17887
                     /locus_tag="J8R83_001185"
     CDS             17012..17887
                     /locus_tag="J8R83_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9574322.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            18153..20036
                     /locus_tag="J8R83_001186"
     CDS             18153..20036
                     /locus_tag="J8R83_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAZ9574323.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(20111..20395)
                     /locus_tag="J8R83_001187"
     CDS             complement(20111..20395)
                     /locus_tag="J8R83_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAZ9574324.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(20385..21119)
                     /locus_tag="J8R83_001188"
     CDS             complement(20385..21119)
                     /locus_tag="J8R83_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAZ9574325.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            21248..21871
                     /locus_tag="J8R83_001189"
     CDS             21248..21871
                     /locus_tag="J8R83_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAZ9574326.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            22063..23184
                     /locus_tag="J8R83_001190"
     CDS             22063..23184
                     /locus_tag="J8R83_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAZ9574327.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            23191..26319
                     /locus_tag="J8R83_001191"
     CDS             23191..26319
                     /locus_tag="J8R83_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAZ9574328.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            26338..29532
                     /locus_tag="J8R83_001192"
     CDS             26338..29532
                     /locus_tag="J8R83_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9574329.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(29678..30385)
                     /locus_tag="J8R83_001193"
     CDS             complement(29678..30385)
                     /locus_tag="J8R83_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAZ9574330.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        10028 a         5579 c         6517 g         8610 t
ORIGIN      
        1 aaaacttgat tttccacctg tactttgcct gaatcgtgaa agcacaggta tgaaaatcaa
       61 gttttttgtt gcgaaaaaac gtcctagtca atcagttggc cgagcggctg gcggctgatc
      121 tgctcctgat caataacgag tgcttcttgg aagtgttgct gcaaaaagta gcggtcatgg
      181 ctgactgcta ggagcgttcc ttgatagtct tgcagcattt cttcaatttc ttctcgagca
      241 tagctgtcga ggtgattggt tggttcatcc aaaatcagga cgttgatttt ttctaaaaag
      301 agtttcagca acgccaaacg gattttttca ccaccggata aatctttgat ccgtttaccc
      361 acatcgcttt gataaaagcc acttttggct aattgccgtc gagcgacttc ttcgtttcca
      421 gtcaatgtga tggcgtaagc cagcaaacgg ctatcgggat cggcaaactg cagctgctgc
      481 ggcaaataac cgatttgcaa gctactacct aatttgatgg tgccaccgta aggcttttcc
      541 tcaccgagta ataatttgag taaggttgat tttcctgcac cattgtcgcc gatgatggct
      601 aaatgatctc cacgatagac tgcaaaactg ctgtctttga atagtacttg atcagcgtac
      661 tgctggtgca agttttgaat gatgaaaact tctttgccag attttccacc attagacaag
      721 ctttgcagcc gatttttcgg gggaggtggc ggtttgacga gtgtcagttt cgccaggcgg
      781 cgttccagtt ctttggcttt tttgaagaag gactcattgt ctccttcatg tgcccactga
      841 cgaaaacgac gaatcatgac tttcaaccgc tggacttctt tttgctgcag ttcgtaattt
      901 tttgtcagct cagccaagcg agcttctttc aagactcgaa aacggctgta gtttccggga
      961 tactcaatca atgcaccttc ttccagttcc catgtttttg tggtgacttg atcgagaaat
     1021 tgccgatcat gagaaacgac cagaaccgat ttttttgtat tctgtaaata gttttccaac
     1081 cagcgaatac tgttaagatc taaatgattg gtcggttcat cgagtaaaag taaatcggca
     1141 tcggctgcta aaattttggc taaagcgact ttaactcgtt cgcctccgct aagttctgtt
     1201 aaccgtgctt cctgacggtg tggaatccct aagccttgca agatcgctgc aatccggtct
     1261 tctaatacgt aaccgcctag ttcttcaaag cgatgctgca gctcaccgta acgggccaga
     1321 cacttctcta agtttgtatc tggttctgtc atcaatgctt cgtagcgact catttgctgt
     1381 ttgaggtcct gtatctcagc ggcagaatgg agcaagtagt ggttgacggt cgcttcggaa
     1441 actgtaagtt cttgttcgac cgtcccgatc tttaagcctt ttttgcgact gataacaccg
     1501 ctgtcgacac cttctctgcc ggtcaagatt tgtaaaaagg ttgatttgcc agttccgttg
     1561 ataccgacta aggcaatttt ttcaccagct tcaatttgac aggataaatc ctcaaataat
     1621 ggattcccgc cgattgtttt tttaatagaa attgcttgta tgatcatgat ctctctcctt
     1681 gagaccactc aaaaaggcca tggttatccc tggcctgtgt tatttaaact cagattatca
     1741 tgagaaaaat accttgagat ggccattgat tttacgtgaa ttcaactgtt ttggacaaac
     1801 ttgtcccgtc aacagcaact gtaaaaccaa ttgcatggct aaatgcgata tggtatcgtt
     1861 ggtaattttc attacttgtt attttagtca tgcgcatcat agtattttcc ctccttcgtg
     1921 tagttgtctt ttccagtgta cctgaaagtg tcagaaagtt caactagcgc tgacatttac
     1981 ttaatattta tcgatgtgta attctgtcag agagcttttt ttatctgact gagggtaatg
     2041 tctcgtggac cacatcattg tattctgagc taaaccagcg ttcaggcgaa atcatatggt
     2101 gtttgataaa aaactttgtc tacatgactt ccttttgcca tttgcttaat accgttgcat
     2161 taaacagctc ttctctttgg aaatctcacc aacatcgcgt tcaggagtat cgttgtggtt
     2221 gcaatggcaa gcggtagcct ttcatcaatt cttgaatgat ttaccgaatg tagcacttgc
     2281 cttctcgcgg tacccgaacc cgaaataaaa ttttagtttg gcgataaaat cggtatccgc
     2341 catcgatact tcatattttt tcgtatcaga ttcatcggaa acttccacat tgacgaacca
     2401 ataagctttg gcatgcttag gtcgttttaa accacaccag ggcgactaat cgccctggtg
     2461 ttcacttttt ttattttact tgaactcatt gactgttttc cctttatttt aaacattata
     2521 aagaccgatg agtgcttgcc gcgtcttttg tttttatcac ggttttttgt gcaaaaaaac
     2581 ctgccgatag ttggcaggtc gtctacgtgt taagctttgg tgtggtcttt agctggcaat
     2641 tggttttcta aatcagttcg gacaacaagc acatcgcaag ctgcgtttct aataacatat
     2701 tcagaaacag aaccaataaa taaacgttct acagcattca atcctgtggc tcctaacata
     2761 atcaaatcta cttgattatc ttctgggatt tctctggcaa taatttgttt tggtgagcca
     2821 tattctacga cagaggttac attattcaag ccagctttct tcgcattgct ttcataatct
     2881 gccaatgttt gctttgccat ttcagtagct tgttctgcaa gcattccatc aaaggatgaa
     2941 acggtttgga aagaacgtgt gtcaatgaca tgtgctaata gaagttctcc gttatttcgg
     3001 atagctacat tgaccgcctt tttaaaagct aattcagctt catcagaacc atctacggca
     3061 accatgattt ttttgtattg ttgtaacata agcattcact cctcaagtca atcgtattgt
     3121 actcttttat tgtagaacac tttagggaaa aagagaatta tttactgctt tggttcagca
     3181 attttttttg caaatcggat actgaaggtg gcagaaacaa taattacgat cagtaaaaag
     3241 accaaggcaa taaagcgttg attgaaaaaa gctgttaaaa tacccattac gcctaaaaca
     3301 gcatatgcag caccgtaaaa ttgtaggaat ccttgatttt tatcattttt gttgatcaat
     3361 acaaaaaaga tatcctgttt attaaataaa taatagctaa cgaataataa tactaaagtg
     3421 gcgataatca ttaaaatcct aatcatgaac aaatcctcca aaataagcaa caaatagaaa
     3481 aagcaatttg ccaagagcaa attgctttat tctttaaaag atggtaatct ccgttaatgc
     3541 cgttgtttgt cctgtagtat tgatcccgcg aattcaagca ggtgggtccc atggtcgtag
     3601 cttcgaacta ccaaatgata aggcatgtta ccagcagtga cacaagacgg gtcccaagat
     3661 atcaataaaa atgttcggtc aacacacaaa gaggacaatt cgaacatcac agatttccca
     3721 cctctatagt agcatatgaa tttaaaaaga gcaatgagag agctcgcaga aacagaaccg
     3781 ttttcttgtc tagttttttg gaggatgctt tttccactct tttatacggt aatactgttg
     3841 acccagagcc tgttcatatt tccctgtatc ttttggctga taatactgag cattcttcag
     3901 tttatctggt aaatattgct gattgaccca agcctgatca aaatgatgag gatactgata
     3961 acccacgcca cggttgagtg atttcgcacc tttgtaatgg ctatctctca aatgatcagg
     4021 aacatctcca gctttgccct ctcgaatatc agcaagtgct gcatctaatg ccatgtaggc
     4081 agaattggat tttggcgaca agcaaagatc gacgacgacg tctgctagtg ggatacgtgc
     4141 ctcaggcaat cccaattttt cagcagctaa tacagcgttc actgtacgag ccgcagcagc
     4201 aggattacct aaacctatat cttcataacc gataaccatc agacgccggc aaatacttgc
     4261 cagatcacct gcctcaacta aacgggcgag ataatgaagt gcagcatcca catcacttcc
     4321 acgaatcgat ttttgaaaag ccgaaataac gtcataatga gcatctccat ttttgtcatg
     4381 ggtaagagct tttctttgga cacattcttc aatgatcgac agtgtaagat gaatccttcc
     4441 ttctttatct gaaggagtcg atagtgtagc cagttccagc ccattcaatg cactccgcaa
     4501 atcgccgttc gttgcacgcg aaaggtgaag aagagcatct tcgtctaact ggattgcttg
     4561 ttgtccaagg ccgcgttctt tatcccttaa agcatgttcg actgccaact ggatgtcttg
     4621 ttctgttaat ggtttgactt caaagatctg tgtacggctg cggatcgctg gattgatggt
     4681 aatataagga ttctcagtag tcgctccgat caagatgatt cggccacttt ctaaatgagg
     4741 aagcagaaaa tcctgttttg ttttatctaa tcggtgtact tcatccaata agaggatcac
     4801 tgtaccactc atttttgctt cttccgctac aacttgtaga tccttttttg aatctgtagc
     4861 ggcgtttagc atgcgaaatg cataattagt agagccggcg atcgcacttg cgatactcgt
     4921 ttttccagta ccaggaggtc catatagaat catggaagag agcatgcgag catcgaccat
     4981 gcggcgtatg atttttcctt ccccgactag atgctgctga ccaacgactt catcgatcgt
     5041 tcgaggtctc atgcgataag ccaatggctg ttgcatagga ttttcctcct tcttgttttt
     5101 acgtccctta attatatcat atttagcaag atgcctagaa agaacagcct tctgttgttt
     5161 tgttttcata gcttatccaa ctaatattgt gtatgataaa gtaggtgaga aaaatgacgg
     5221 ataaacaaaa gatagatgaa tttttttgga ataaaacgac gccagaagtg gcacgggatt
     5281 tattggggat gtatttggag catgacacac cagaaggaag attagctgga tatattgtag
     5341 acgcggaagc atacctaggt ccagaagacg aggccgccca tagctatggt ttaagaagaa
     5401 caccgcgtgt gcgggcaatg tatgaaaaac caggtacgat ctacctttac acgatgcata
     5461 ctcatcggat tttgaacatc attactcagc cagaagggat tcctcaagga gtaatgatac
     5521 gtgcaatcga acccgccgca atgattgatc aaatgagtaa aaatcgtggc ggaaaaactg
     5581 gtccagatat cagcaacggt ccgggaaaat tagtggaagc attagcaatt cctcaagaac
     5641 tttatggtca gtctatagca gatagttcgt tacgcttagt ttttgagaaa aaaaagacac
     5701 caaaaaagat caatgctttg cctagaatcg gtatcccaaa caaaggtgta tggacagaaa
     5761 agccgttgcg ttttgttgtg tcgggaaatc cttatatctc tttacaaaga aaaaaccaaa
     5821 tcgagaaaga ttggggttgg aggaaagaaa atgaaaaaga aggatctatt aacatattta
     5881 gatgaaataa ttgaaaaaca agtgacagac tatgatgtag ctttagattg ggatacaaaa
     5941 aatcatacga tcgagatcgt tgttcgcttg tttgcagaaa ataaagcaca atttgagatt
     6001 gatgatgcag aagggatcgt ttcgcaagaa ccaattatcg aatttgaaga cggcgtactt
     6061 ctttttaatc ctcagaaatc tgtttttgat gaacgcaatt atctagcagt aatcccttat
     6121 gaaggaaaaa aagggttggc aaaatcagta gctgattctt tagtggaata tctaaatgaa
     6181 gtattagctc aagggcaaag cgatttgctt gattttttgg atgaagacga tgacgaagct
     6241 gtattcgagc ttcactggga taatcaacaa ctagcagaat tagtagaagt aaaacagcaa
     6301 aatgaagcag atacttattt accgtaccca agttattaag gagtgacaga tatgaaatgg
     6361 aatgaagtaa aagtagaaac tgaaagtgaa gcagtcgaag cagttgctaa tattttgatg
     6421 gaggcagggg cgagtggtgt cgcgattgaa gattctttag atgttgaaca ttttcagtcg
     6481 gatcaatatg gtgagatttt agataaaaat gattttacat cgctgaaaga aggcgcacta
     6541 gtcatggctt attttccgga aacgactttc ttaccggaaa tcttgccttt tatcaaagat
     6601 cgtatcacac aattacctga gtttggtcta gctattggaa aaaataaagt aacagttagt
     6661 gaagtagagg aaagcaactg ggcaacagcc tggaagaaat actatcatcc ggtgcgtatt
     6721 acgcgaatgc tgacggttgc gccaagctgg gaaaactacc agacagaaga tcctctagaa
     6781 aaaattatca cactagatcc tggtatggca tttggcacag gcactcatcc cacgacttcc
     6841 ttgacattga cagcactaga aacagtcttg cgtggtggtg aaacattgct agatgtggga
     6901 actgggtcgg gcgtgctaag tattgcagca aaatatcttg gtgcaaaaga tgtctatgcc
     6961 tttgatttag acgaagtagc cgttcgttcg gcgaaagaaa atatggatat gaatgaaata
     7021 gccaaagatg tccatgtatc agctaacgat cttttgacag gaatcgagat tgaaagtgat
     7081 gtaatcgttg cgaacatttt agcagatatc atcttattga tgatcccaga tgcttggcgt
     7141 ttactgaagc aaacaggcac gctgatcgtt tcaggaatca ttgaagagaa gaagcaaatg
     7201 gttctggatg ccatgttaga acaagggttt atcgtggatc aaattttcca gcaaaaagac
     7261 tggtatgcaa ttattttgaa aaaaccagag gtggaataga tgcagcggta ttttttaaaa
     7321 gaatcatatg aatcaaaaga ctattttgtt ttagaagggg aaaactatca ccacattgta
     7381 cgggttatga ggatggaacc cgaggatgaa gtttttttgg cattcaatga tcaaatagcc
     7441 attgttgcag aaatcacgga gattactgaa gaggctgttt atctgaaaga aattaaaaaa
     7501 gaagaaaatc aaaaggaact gccaagttcg attaccatag cgagtggcta tcctaaaggg
     7561 gaaaagctgg attggatcgt tcagaaatcc actgaattag gagcgcaagc ttttcttggt
     7621 ttcccggcat cagcctctgt cgttaaatgg gatgcaaaaa aacgtatgaa acgacaacaa
     7681 cggcttgaaa agattgctca agaggcagcg gaacaatccc atcggcagat cgtgccatca
     7741 gtagagttat tggaaacgaa acaagattta tttgagcggc tagatgatta tgacgtggtc
     7801 ttggttgctt atgaggaatc agcaaagcaa ggcgaaaaat caaatgcagc caaaattctt
     7861 agtgaaacaa aaccagatag tcgaatctta gctgtctttg gaccagaagg tggattatcc
     7921 cgcgatgaag tcgattattt tgtagaacac aaagggatac tttgtggatt aggaccaaga
     7981 atccttcgta cagaaacagc acctctttat ttattaagtg ctgctagcta tcaatgggaa
     8041 ttaatgaatc cttctttcag ctaacgttct tcattaataa aagagtatcg acagaaagaa
     8101 ttgaaaaaat agtcaacaat ttgtataata gaaacaatta tttatacaat ggatacgaaa
     8161 aatcgtttga aaaagctttt aaaaagcgaa catttccgta aaaaaacgta taactgcacg
     8221 gattttggga caattatcaa acagatattt gtcccgattc ccgttttacc gaaaaaagaa
     8281 agggggatcg attcctgtga caaaagaaga aattttaacg ggacccggtg tcataaagct
     8341 cgttagtcaa tacatgggtc ccgaacatgt agcatttgtt gagaaagcat gcgaatacgc
     8401 gactgctgca catgacggac agtttagaaa atcaggcgaa ccctacatta ttcatcctat
     8461 ccaagtcgca ggtatattag cagatttaaa aatggatccc catacagtgg ctacaggctt
     8521 cttacatgat gttgttgaag atacagaaat cactttagaa gatctgagag aagaatttgg
     8581 cgatgacgtt gctatgttag tggacggcgt aaccaaatta gggaaaataa aatataaatc
     8641 ccacgaagag cagctagcag aaaaccaccg aaagatgctg ctagcaatgg ctcaagattt
     8701 acgagttatc atggtcaaat tagctgatag actacataac atgcgtacgt tgaagcacct
     8761 gcgagaagat aagcaaagaa ggatcgctca ggaaacttta gaaatctatg cgcctcttgc
     8821 acatcgtcta gggatcagcc ggatcaaatg ggaattagaa gatacagcac ttcgttatct
     8881 aaatccaaaa cagtattacc gtatcgtcca cttgatgcag acgaagagag aagaacgtga
     8941 aaaatacgta agtggtactg ttgaagatat tcgaatagcg acagaagagc tggggatttt
     9001 tgcagaaatc tatggacggc caaaacacat ttattcaatc tatcgtaaaa tgaaagatca
     9061 gaaaaagcag ttcaacgaaa tttatgactt gctagctatt cgagtgatcg tagattcaat
     9121 caaggattgt tatgctgtat taggagcaat ccacacaaaa tggaaaccaa tgcccggcag
     9181 atttaaggat tatattgcca tgccaaaagc taatatgtac caatctttgc atactaccgt
     9241 gatcggtccg gcaggaaatc cggtagaaat tcaaatccga acacaggaaa tgcatgaaat
     9301 cgctgaattc ggggttgctg cacactgggc ctataaagaa ggaaaaaatg aaaaagtaga
     9361 accagatggt atgacgaaac aattaagctg gttccatgag atactcgaac ttcaagacga
     9421 aagctatgat gcttctgaat ttatggaagg cgtaaaagga gatatcttta gtgataaagt
     9481 ctacgtcttc acaccaaaag gagacgttac tgagttacca aaaggatccg gaccattgga
     9541 ctttgcatac agtatccata cagatatcgg taacaaaacc actggtgcaa aagtaaatgg
     9601 caaaatggtg cagcttgatt acaaattgaa aaacggagat atcattgaga tcatgacttc
     9661 tccaaattca tttggcccaa gtcgcgactg gttgaaatta gttgctacta gcaaagcaag
     9721 aaataagatc aaacgtttct tcaaagccca agatcgagaa gaaaatgtga tcaaaggcca
     9781 cgaatccgtg gtcaaatgta ttacagatct aggatttacg cctaaagata ttttgacgaa
     9841 gaacaaactg caagaagcac tcgatcgttt taattatcaa acagaagatg atctctatgc
     9901 agctgtaggg tatggagaag ttagcccctt gacgatggcc aatcgtctga ctgaaaaaga
     9961 acgtaaagaa caaaaaatcg agcagcaaaa gcaagaagca gaagaaatca tgaatcagcc
    10021 gaaaaaagaa cctgacaaaa tgaaagtacg tcatgaaggt ggcgttgtca ttcaaggggt
    10081 agaaaactta ctaattcgta tcagtcgctg ctgtaatccg attcctggtg atgatatcgt
    10141 tggttatatc actaaaggca gagggatatc cattcatcgt cgagattgtc cgaatgttca
    10201 gcctgacaaa ccaaatgtag cagaacgttt gattgaagtc gaatgggaag atacatcgaa
    10261 tacacgaaaa gagtatgatg cagatttgga aatttacggc tataatcgtt caggcttatt
    10321 gaatgatgta cttcaaacag tcaatgcgct aacgaaaaat ctcaacagcg ttgaagcacg
    10381 gacgaataaa gataaaatgg cgacgatcca tttgacggtt ggtatccaga atttatccca
    10441 cctaaagagt atcgtggata aaatcaaagc agtacctgat gtctacagtg tacgccggac
    10501 gaatggatag gaggacagat atgagagcag ttgttcaacg ggtaagtaaa gctgctgtgt
    10561 cagtcgatca gcaagaaatt ggaaaaattg gctacggcct acttgtttta ttaggcattc
    10621 atgaaaccga tacgcaaaaa gatgtggact atctggtaaa aaaaattgca caaatgcgta
    10681 tttttgaaga tgaacaagga aaaatgaata ttagtgtaga agatgtggga ggacaaattt
    10741 taagtatctc tcaattcaca ctgtttgcgg atacgaaaaa aggaaatcga ccaagctttg
    10801 tggaagccgc acgaccagaa acagctattc ctttatacga atcattcaat gaaggaatca
    10861 gaagtcgcgg catcacagtc gctaccggac aattcggagc agatatgtcg gtttctctcg
    10921 tcaatgatgg acctgtaacg atcattattg attctaaaaa caaataaagt aatctggttt
    10981 tcactagtaa aaactatgaa acacgtcgct taagttagac tgataaactc taacttaagt
    11041 ggcttttttg tctgcaaaaa gcgcttcttt tgtcagcagt cggaaaaaaa gttaagctta
    11101 aattatacaa gttatttttt ataggaggtt gctgaagatg aaagaagtac cagtagtaga
    11161 tatcaaaatc acagatttaa aaaaattgta tcaaaaagga tacaacatgt tggaggagtt
    11221 acgccatgaa gcggacgctc ccgtcgtcaa agcaaagatt ttcaataaag aagctatcac
    11281 gatctacgga tcatcagcag caaaagtatt ttatgatcca aggaatttca aacgaaaagg
    11341 tgctatgcca aaattagtat tgaagacact ttttggtcaa ggtggagtac agactttgga
    11401 tggagctgct catcaccatc ggaaaaatat ttttatggat ctaatgacac cggaaagaat
    11461 ggaagattat catcgtatct tagataagaa tctgacacaa gcacttgaag cacagcatgg
    11521 tcaatttgaa ctatttgatt taagtaagat ggttttcttt acatctattt gcgagtgggc
    11581 aggtatcaat ttatcagcga tttctaaaga tgaggtcgaa aaattagcag aatatcaaat
    11641 ctctatgatc agcggaacgt ttacttctcc gattgatcac ataaaaggtg tcgagaatcg
    11701 caaaaaatca gaaaaatggg cgcaaggctt gattgaagaa gctcgacaaa atcctgtggc
    11761 tggaaaagaa aatgtggcat tatatgcttt tgccaatgcc acagatttag atggtcagct
    11821 tttacctctg gaagtggcag ctgttgaatt attgaacatc atccgtccaa cggttgctct
    11881 aactgtgtgg gcggcattga tgggacatgc acttttcagt agaccagatt tgtatcagca
    11941 attaaaaaat gacttttcga cgttacaaga tccgtttatt caagaaatga gacgctatta
    12001 tcctttcttc ccaatgctac ctgcgatttc gctgaaagaa gtagaagtag atggttatcg
    12061 tataccagaa ggcagttggg ttattttaga tttatatgga acagaccatg atgaacgaac
    12121 agttgaagcg ccagattcct ttatgatcaa acggtatgta gggaaagcaa aagatatttc
    12181 ctataaagaa gaatatgaga tgattgcaca aggcggggga aattttcgac aaatgcatcg
    12241 ctgtgcagga gaatggatca ctcttcatag tctacgtgtg ttttccgatc agctagtaaa
    12301 taagtttgag ttctctgtac ctgaacaaga ttggacgatt ccattcaatc agtttccgac
    12361 ttatccgaat agccgagcgc tactttacaa gaattagatt agcataaact tatcgaaaaa
    12421 aaggaagatc aaacagtgct gatcttcctt ttttcatatt actataaatt gataaggtca
    12481 attgatcaaa atccacgaaa tgcttcatca atggtttgat aatcttcatt ggataaatgc
    12541 aaatctaaag cttggacatt gtcagatact tgctctggac gcttagctcc aggtataact
    12601 acagacactc gtggattctt catgtaccaa gctaaaacaa gttgcgcagg agtggcttgg
    12661 tatcttttag caatggggcg aagtacatcg acagcggtta aaatttctct gaaacgttct
    12721 ccttggaaat ctggatttct ttttcgagga tctccttcac caaattgttt ttcctcacca
    12781 agttcatatt ttcctgtcag caaaccggaa gcaagaggaa aatagggaac aaaactgatt
    12841 ttgttttttt caagataagg gaataattct ttttcagcct gccgatggat caaactgtat
    12901 ttatcttcta ctacatcgac atatccatct gcattcgctt ctttcaattg ttctaacgtg
    12961 aagtttgaca caccgactgc tcggattttt cctgcttctt ttaattcgtg caatgtagca
    13021 actgattcat tttttggtgt gctttcatcc ggaaagtgga tataaaaaat gtcgatgtaa
    13081 tcagtttgca gacgttttag tgcatcttcc accgattgtt tgagaaactc aggagaatta
    13141 tcaaatgttc gccctttatt tggtacatga gcagcttttg tagcgatgac gacacgtgag
    13201 cgatcatatt ctttttcctt cagtacctcg ccaatcagtt cttcggaacg gccgtttccg
    13261 taagcataag cggtatcgat caaattgatc ccgctattca aagctgtacg aactacttgt
    13321 tttcctgtct catcttccaa accgtcaaaa agattatgtc ctccaacggc atttgctcct
    13381 aatccaagct gttctgcgta gacttgtgaa tgtccgattc ttatttctgc catagctgat
    13441 tcctcctttt tgtctagtct aaaacaaaat accaaaaagc tgaactaaaa cgtttttgtg
    13501 aggggaaata gtcagatatc tcttgacttt gagactggtt tttagtaggt tataagtaat
    13561 atcgaatgtc aatgaaagag cgagtaagtt tttgaaactt tacaagagag gatcatcgag
    13621 gctgaaaatg atctaaagtt tcattagcct aaagacactc tggagatgga cgagtgaaaa
    13681 gccgtcccgc gtacgagcgt tattcgtaag aggaaagaga aatctttcaa aattaggtgg
    13741 taccgtgtat gaatttcatt cacccttgtt catgatgaac aagggtgatt tttttattta
    13801 catagctaag aaagggagag aaaactatga gtttccaaag accaaaagga acaaatgata
    13861 ttttgccagg cgaatcagaa aaatggcagt ttgtcgaaga aacagcacgt ttattattca
    13921 gagattatca gtataatgaa atgcgtacac cgatttttga acactatgaa gtgatatccc
    13981 gaagtgtagg ggatacaacg gatatcgttt caaaagagat gtatgatttt tatgacaaag
    14041 gggaacgcca tgtgacgctt cgaccagaag gtacagcacc aatcgttcgt tcttttgttg
    14101 agcataaatt gttcggccca gagtatgcga aaccgttcaa aactttttat atgggaccaa
    14161 tgtttcgcta cgaacgccct caaaaaggac ggttacgtca attccatcaa atcggagtag
    14221 aagcatttgg atcagaaaac cctgcaactg atgtggagag catggtgatg gcacttgatt
    14281 tcttcaaaca gttggggatc acgcaaatcc ggctagtcat caattcatta ggtgataaag
    14341 aaacgcgtca agcctatcgt caagcattga tcgactatct tttacctttt gaatcagagc
    14401 tgagtgaaga ctctaaacgc cgccttcatg aaaatccatt acgcgtattg gacagtaaag
    14461 acaaacgaga tcaaaaattt gtggcagaag ctccatctat cttagattat ctaagcgagc
    14521 ctgctcaaaa acattttgat accgttgttt ccatgctgga tgcattggct gttccttatg
    14581 aaatcgacag taatatggtt cgcggactag attattacac acatacgatt tttgaaatca
    14641 tgagtgacgc accaaaaatg ggggcacaag caacgatttg cgcaggcgga cgttatgaca
    14701 atctagtgga agaactaggt ggtccttcaa cacctggctt cggatttgca atgggtatcg
    14761 agcgattact cttgactatg gaggcagagg aagtagttat ccctgcattt aatgagttgg
    14821 atgcttacgt ggtcgcactc ggagacgaaa caaatatcga agcattgaaa gtggtccaag
    14881 cgattcgaaa ctttggtttt tcagctgacc gcgacttcat gaaccgtaaa gcaaaagcgc
    14941 aatttaagac agcagataaa gcgaatgcca aattagtatt ggtgatcggt gaagatgagc
    15001 ttgctagtca aacgattaat gtcaaagcaa tggcaagccg aaaagaaaaa agttttccat
    15061 tagaagagat atatgaacat tttgatgaag tctatgatga aatgacttta ttcgagtagg
    15121 aggaaaaaaa taaatggcac aaagaacgat ctattgcgga ttagtttccg aacaacaatt
    15181 agaacaaaca gttacattaa aaggatgggt acaaaaaaga cgagaccttg ggggagtaat
    15241 ctttatcgac ctacgtgatc gtgaaggaat cgttcaaatc gtctttaatc ctgaaatcaa
    15301 caaagaagca tgggaaatcg cggataaatg tcgcagtgaa tacgtgatcg aagtgactgg
    15361 ggaagttaga agacgcggag aaaatgcagt aaatcctaaa atggccactg gtgaattcga
    15421 agtgattgca agtgaaatcg tgattttgaa tcaagcaaaa accccgccat ttcaaattga
    15481 agatgatcaa gcaatcagtg acgaaatacg tttgaaatat cgttatttgg atctgcgtcg
    15541 tccaaaaatg actaaaaaca tcaaattaag aaatgcgaca acaaaagcga ttcgtcatta
    15601 tttagatgat aatgactttc tcgatatcga aacaccttac ctagggaaat ctacaccaga
    15661 aggcgcaaga gactacctag ttccttcacg tgtccatgct ggacatttct atgcgttgcc
    15721 gcaatctcct caattgttta aacaattgct gatgaatgct ggattcgacc gttattatca
    15781 aatcgttcgt tgtttccgcg atgaagattt acgtggagac cgtcagcctg aatttacgca
    15841 agtagatatt gaaacaacgt tcttaacagc agaagaaatc caaacttaca cagagggatt
    15901 gattgcgaag gtaatgaaag aagttcgcgg tatcgaagtc acattgccat ttcctcgtat
    15961 gacctatgat gaagcaatgg ctcgctacgg cagcgacaaa ccggatacac gttttgatat
    16021 ggaattgatc gatctaagcg atacagtcaa agaagtagaa ttcaaagtct tccaaatggc
    16081 tcttgaaaac ggcggtgtcg tgaaagcatt gaatgctaaa ggcgctgcag atcgctactc
    16141 acgaaaagac atggatcagt taggtcaata tgtaggacaa ttcggagcta aggggcttgc
    16201 atggctgaaa gtagaagaag acggattgaa aggtccaatt gctaaattca tgggagaagc
    16261 aacagaagca atcattaaag caacagatgc aaaaccaggt gacttgctga tgtttggcgc
    16321 agataaaagt gaaatcgtcg ctgctgcatt aggtgctatc cggacacgtt taggaaaaga
    16381 attaggacta attgatgaat cgaaattcaa tttcttatgg gtaactgatt ggccacaatt
    16441 tgaattttca gaagaagaag gtcgatatgt ctctgctcac catccattca cgatgccaaa
    16501 agaagaagat atcccgttat tggctgaaga ccctgcaaaa gtctatgcag aagcttatga
    16561 tatcgtcttg aacggttatg aattaggcgg aggttctatc cgtattcata ctcgtgagct
    16621 tcaagaaaaa gtactagaaa ctctaggctt tacaaaagaa caaatggaag aacaatttgg
    16681 tttcttgtta acagctttag attacggatt ccctccacat ggcggtattg cattaggatt
    16741 ggaccgtttt gcaatgttat tagccggaga agataatatt cgtgaagtca ttgcctttcc
    16801 taaaaacgga aaagcagcag atgtgatgag tgatgcacca agtatggttt cgcctttaca
    16861 attgttcgaa ttgaatattg atgtaacgaa tatagaagaa tagccgataa aaaggtaaaa
    16921 aggatttgtc gaatacgctt cttttgacaa ccttgattta attgaaaaac actttataat
    16981 gaagccataa catataaagc ggggcttttc catgaaaaaa acattcgaaa attgggctta
    17041 tcatgattac acgaccaagc tttcggtatc tatcgtttat gcgttgatcg catcagtcgc
    17101 attgaatttc ttttatcagc caggacatat ttattcaagt ggtattactg gtctagctca
    17161 gattttgacg actttgtcaa aatcactgat aggattcgaa gtaccggtat caacaacttt
    17221 gtatttactg aatatacctt tgtttgtatt ggcgtggtta aaaatcggga agaagtttac
    17281 aattttcact tttatcacag tcactttgac ctccctttgt atccatattt taccggaaac
    17341 agtcctatct accgatccaa tcatctgtgc gttgtttggg ggggctgtga tgggactagg
    17401 tattgggcta gcgttgagaa acggcctatc atcgggcggt ctagatatcg tgagtatcac
    17461 gattcgtaaa aaaacaggaa agtcgattgg ttctatttcg atctacttca atgcattgat
    17521 cgtttttgtt gccggaattc tatttggctg gcaatatatg ttttacagta cgttgtctat
    17581 tttcgtcagt ggaaaagtaa ctgatgtcgt ttatactaaa caaaagaaga tgcaggtaat
    17641 gatcgtaacg aaacatccag aaaaagtagt aaatgaaatc caaaactgta tgcgtagagg
    17701 gatcacgatc atcaatgaag cagaaggtgc ttataagcat gataagcaga cagtattgat
    17761 gacgatcgtt acacgatacg aactgcctct acttagagaa gcaatgaaag cttctgatcc
    17821 acaagctttt gtaagtattg cagaaaacgt ccagatactt ggtcgtttct atgaggatgg
    17881 catttagatc gagtttgaca aaaattcatg aaatactgct gtagacagac gttcgtttgt
    17941 ctgcagtttt tttctaccat agtagaatca gcaaagaaaa actgcttttt tatttgaaat
    18001 tttcttaaag ttgaaaaaaa gcatgtttat ttttttaaat ttatgggatg atagaaaaaa
    18061 atagtagaga aaggacacga ttctacttgc tattttcact taatacccgt atattacgaa
    18121 tgaaaaaagt ttatgaaaag ttggaatatt gaatggaaaa acaaaaaagg ttaaaaaaca
    18181 gccgctacat cactgggttt gatgggctcc gttcattagc tgtggtgggt gttatcttct
    18241 atcaccttct gccaactagt atgaaaggcg gctatttggg cgttccgatt tttttcgtcg
    18301 tatctggtta tttgatcacg gatctgctgc ggcaggaatg ggaacaaaat ggaaaaatca
    18361 atatttggca attttatgtc agaagaatga agagactcta tccggcactt gtttttatgc
    18421 ttgtgacagc ttcggcttat atcactttgt ttcagcgagg gctgttaaac aatcttcgag
    18481 gagttgtggt cagcagctta ctgtatgtca acaactggtg gcaaatcaat aacggtttat
    18541 cttatttcga tcgatttgct aatgagtcac cgtttacgca tatctggtct ttagcagtag
    18601 aaggtcaaaa ctatttggtt tggccgatct tgtttgtatt gttgatggta tttgttcgta
    18661 aaagaaaatg gatcttttat actgtgttag gtacatcctt cctctccgcc atcttgatga
    18721 tgatcttgta tacaccagga ggcgatccaa cccgtgttta ttacggtacc gacactcgtc
    18781 tgttttctat atggttggga agtgcgcttg cgtttgtttg gccaagtacg cgtttaaaga
    18841 aaaacatccc gaaacaagcg aaaaatattc tgaatatcgc tggaggaatc tcgcttttgg
    18901 cactgattct ttgcttcttc tttttagatg atcattacaa tttcatctat tacggaggaa
    18961 tgctcctagt gagtctgtta tgcgtagtgc tagttgcagt gacagcacac cccggagcaa
    19021 gtttgaatcg atggctgaca aatccagtat ttacttggat tggcaaacga agctatggca
    19081 tttatctgta tcagtttcca gttatgattt tttatgaagc aaaggtgact gatattgccg
    19141 atcatgtttt gttgcatact ttagtggaaa tcacattgat tctaatcatc agtgaacttt
    19201 cttatcgata tgtggagcgt ccgctagcac gttttgatta tggtcgtaca ttccaagtga
    19261 tgaaaggatg gttcagcaaa ccgatcatca gtaagagcaa accatgggtt gttccaggca
    19321 cattacttgt agcaattgca ctcgttggtt tcgttacggc accgaaaaac gctgtaacag
    19381 ccgatcaaaa acaactgcag gcaaaaatcg ctgaaagtaa aaaattagca gaagaaacca
    19441 gaaacaattc agaaaacacc actagttcgg ttgaccaagc gatccttgat aagtacgagt
    19501 tgtccaaggc acaagggaat aaggcacaaa aattagaact aacggcattt ggtgattcag
    19561 ttatgttgga tgctgcaacg gatctacaag aactttatcc aaaagtagtg gtagatggag
    19621 atgtcggacg acaattatat gccagtgtac cgtacattga aaaattaaag gaacaagatt
    19681 tgttgaaaga cactgttctg attggactag gaacgaatgg ctcattctcg gaagctcagt
    19741 ttgatagtgt gatggatgca atcggtgatc gaaaagtata ctgggtcaat gtccgagtac
    19801 cgacgaagcg ctggcaaaat gacgtgaatg cgatgcttga acagatgacg aaaaaatacg
    19861 acaatatgac gctgattgat tggtacagct acagtaatga ccatagtgac tggttttatg
    19921 atgatcaagt ccatccaaat cctgaaggga tgacacatta cattcactta gtcagcgaag
    19981 ccttgctagg aggaagttca agtacgaaca gcagtgagac aaacgtgaca gaatgatagc
    20041 tacaaaaaac ttcaggcaaa aacatttgtt tttgcctgaa gtttttttat atttaccgtg
    20101 tttttaacat tcatatagat tcaggaagca aaacggttga gtgtgtctgt aaataacgtt
    20161 ctttttgttt tcgggtgagt tttttgaatg cagcttctgc ttttgttgct tcgcttcttg
    20221 aagaaaatac ttctgcatgg atcatcttaa caggtcttct tttttgaaga cgagtatatt
    20281 tagcaccagt accattgtta tgttcctcta atcgtctaga aagatcggtt gtatatccac
    20341 cataaaatgt ctgatcttta cagaataata cgtaaaaata atgttcattt gccatagagc
    20401 atctcacgaa tctctgcagt gtattctcca tccatattgt aagtgatcaa tggtggagcg
    20461 actttgaatc cgtctaattt gccttctttg attccttcaa ctaacaaaat atttgcctct
    20521 tttccaggtt ttgggtaaac aaattggatc cttttaggtg caattcgata gtcttccatg
    20581 acctgaatga tttctaagaa ccgatcagga cgatggacca tagtaaagcg tccatttgtt
    20641 tttagtagct tacttgaaat atcgatcact tcttctaacg tcgtatgaat ctcatgacgg
    20701 gcgattgcca ggtgtttatt agggttcgtt ttatttgttg gcagcccttt gaaataaggt
    20761 ggattacaga cgactaagtc acaagaatta tgtcgaacga cagataagct gtctttcaga
    20821 tcgatggtgt ggacagtcat ttgttcattt aaatggttaa gcgcgatact acgtcttgcc
    20881 atgtctgcta gacgaggttg aagttcgata gcgtcgatag ccgcctgggt tcgtttactt
    20941 aaaaaaagtc caactgcgcc atttcctgca caaaggtcaa caatcttccc ttttttaggt
    21001 acacgggaaa agtgagcaag cagcacagca tctaaagaaa aagaaaacac tttggaactt
    21061 tggataatct tgatatcttc tgcgtataat tggtcgattc gttcgtcttc gtgaagcatg
    21121 gattccctcc aaaatgaaaa aaatagtcgt ctgtattata ctatttttat taaaaagaac
    21181 caaggtggct tgtcaaacct ctatttttta tgcatactat gaccataaga agggaaagga
    21241 agagactatg ttttatcgat ttatgcgcgg ggtagttcga gtactattag ccttagttaa
    21301 tggaaatgcc cgctatgaga ataaagaagt tttaccgcaa gatgagaatt acatactagt
    21361 tgctccccat cgtacttggt gggacccatt atatctggcg gtagctgcag cacccaagga
    21421 attcagcttt atggcaaaag aagaactgtt caaaaatcca gttctgcgat ttatattaac
    21481 tcgatccaat gcttttccag ttaaaagaga aaatccagga ccaagcgtca ttaaaacacc
    21541 tgtaaagatt ttgaaatcga caaatttgag tttgatcatg tttcccagtg ggacaagaca
    21601 tgctacagaa cttaaaggcg gaatggcatt gatttccaga atgtctaaag cgaaaatcgt
    21661 gccagctgta tatcaaggtc cgttgacact tggggatctg ttcaagcgtc agagagtgac
    21721 agtgcgtttc ggcgaaccaa tcgacttatc agatatcaag aaaacggata aagaaggtat
    21781 ggcggagatc gaacgacgaa cacaagcagc ttttgacaaa ttggacaaag aagtgaaccc
    21841 tgatttcaaa tatgaagtca aaaaaaaata aaatgataag tttatgcgtg ggcggtcttt
    21901 tgaatctact gtcctgttca gttcagactt tttcaatgaa aacgagggag agacgtcaag
    21961 tctgccctct ttttgcgttc caatatgtaa aatagaagac aggtgtcatg taatggatca
    22021 aagtgttata ataattagaa ggacattttt tgaggtgatt gaatgcgttt tttacataca
    22081 gccgattggc atatcggaaa aaaactacaa ggttatgact tgattgaaga ccagcgtcat
    22141 gtactatctt ctatactaga tatcgcgaaa gaagaaaaag tagaggcaat cgtgattgcc
    22201 ggagacttat atgataggag tgtcccagct gttgatgccg tagaattata caatgaattg
    22261 atggtcgatt ggaatttaaa ggaaaagatc ccgatttttg ctatatcagg aaatcacgat
    22321 agcagtacga gactttcagc gggtacgcca tggttcagtt attcgaacta ttttttgcga
    22381 acacagctag cagaagcatt tgaaccagtc gagtttaaaa acgtacaatt tttctttctt
    22441 ccttactttg aaccaattgc agcgagatta tattttgaag atgacaatat ccgaacgatc
    22501 aagcaagcgg tagccaaggt gatagataaa atgcaggagc tatttgattc agaaaaaaaa
    22561 caagtattga ttagccattt ttttgtaatg ggaagtgtaa aatctgattc ggaaacgaaa
    22621 atcgaagtag gcgggttgga ttcgatccct ggtgaactac ttacaccgtt tgattatgta
    22681 gcactaggac atttgcataa tcaagctgct ttgagacagg ataatgctcg ctatagcggt
    22741 tccccattga aattctcttt atctgagatc aaccaaaaaa aaggcgtatg gatcgttgac
    22801 ctgacaacag gcctggagtt gaattttagg gagatcgaac ccctgcatga tattgaagaa
    22861 ataacagcga gtttcaaaga attgctggat cctgcctttt atcagtccgt caatcgggag
    22921 aattacatct atatctatct cactgataga acgatcatcc cgaatatgat gaaccagctt
    22981 cggcaaatat atcctcgtat tttggggatt gaacgggcaa acggtcgagc agaacaaaca
    23041 aagcgcaaac gaaaagtact agaaatgaaa gatcctcaaa aattagcaga agcatttttt
    23101 agtgaaatga cggaagagca gctaactgca aaccaagaaa aatggctcgg agaaacgttg
    23161 caagaaatca tggaaatgga atgatcaaga atgaaaccga aaaaattaca acttaaaaat
    23221 tttggtcctt ttatcaatga gaccgtagat ttttcacgtt tgacagaagc accgcttttt
    23281 ttgatcagcg ggaagacagg agctggcaaa acgacgattt ttgatgggat caccttcgca
    23341 ctttttggtg aaacttccgg aagacttcgc tctggaaaag agatgcgttc tttgtttgct
    23401 acaccagacg aagaaacaag cgtgactttt tcttttgaac atcagcagat gagctatgaa
    23461 atcgaacgaa aaccagaaca agttttagca aaacgaaaag gaaacggaac aaaaaaacag
    23521 gcagccaaag taacgttgac catttttgat gggaaaggaa aagaaataaa acaaatcaca
    23581 aaacgtacag aagcagatca gttgatcaga gaactgatga atctcgatgc gaaacagttt
    23641 tctcaaatcg ttttactacc ccaaggagaa ttccgtaatt ttttggtttc atcaagcagt
    23701 gataaagaga ctgttttacg tcatttattc ggtactcaat ttttccaaca gttcaatgag
    23761 cgattaaaag aaaaagcaaa acaacagcaa caaaaattgg atcatttaga gcaagagctg
    23821 catcttctgc aaaaaaggtt tgttttagtc aaagaagagg aaccagcagc agggtttgaa
    23881 gccgttttag cccaatggac aaaccatcag gcaatactcg aaaaacaaat cacggaagaa
    23941 aaagaagctc taacggaact tcaggaaaaa caaaagcaac tagaaaattc ctactatcgt
    24001 tttgaaagct tgaaaaaaag ttatgaagaa aaaacgatat taataaacaa gcaaaaggaa
    24061 ttagctgctc aaaaagacga aatagaggaa aagaaacgat ggattgggta ttatgaattt
    24121 acgcaacgat tagtcgaacc aatccagcgc ctacaagaaa taaaagttga aaaaatagaa
    24181 ctgtcacaaa aaagtagtga gcaaacaaag aaactagcga tgactacgca gaattatgaa
    24241 gagtggcaaa aaaatgaagc aaaccgcgta cgccgacaaa caaaaatcaa agaagctgct
    24301 caaaaactgc aaaacaaaca gatgatggtg ccaattgtcg aatccttacg tagtaaaaaa
    24361 caagacgcag aacaattaac aatttcattg gataaagaag aattgaatgc cgagaagctg
    24421 tatcaaaatc tcgctatcta tcaggaaaga actcgaattc ttcaagaaaa tttactggat
    24481 caggaaaaac tgcaagaaga tcgtcttgct tttggacagt taaaatatct agatgaaaag
    24541 cagcaagaaa tagaaaaaca aaaagcaaaa gacactgggt cgctcgcaca gataagagaa
    24601 gaactcaaaa aagcaactga agaaataaca aaaaatagtc agctattgaa agaacagaca
    24661 gaacaagcag aacagctgaa aagccaatgg gcaaagcagc aaattgctcg tcttcagctt
    24721 tttttgcgtc caggggagcc atgtcttgtt tgtggatcaa cggaacaccc catacaacaa
    24781 ttaaaacacg aacagccaaa taaggaagat atcttaaaag tagaacaaca actggcagaa
    24841 gctgagtctg ctgtagaaag aactcagcaa atcattgcca aaagtgaagc acatgaaaat
    24901 aatcttcaac aacaattatc agatttagaa caaaaaatca tggcaacgaa tatacaattg
    24961 gctgaacaag aagaacactt gcaacaggct ttgaaaaagg catttcctga gataacagaa
    25021 caaaaaacaa aaacaactct tgtagtaatc gaacaatctt tagatagacg aaaaagcaag
    25081 atggccaatg caagaataga gctggaagaa ataagacaac aagcagaaaa gctcgaacaa
    25141 caattagctg tctacaaaca gcagcagaca gaaaaaaata atcagctcca gcaactgcaa
    25201 ggagaaatca aaagtttaga acaacaattg caagatacgg atagtaactg tttagaagag
    25261 gagatacgac gacttgaaaa acagttagaa gaagactcga atcaactagc tgttgagcag
    25321 aaagcaggag tgcaattgtt gcaagatctt catacgcttc ggacacagct tgatcttcaa
    25381 catgaacaaa tagaaaaaat agatgaaaaa atagaaaagg aacaagaaag aatagctaaa
    25441 aagttagaaa gccagtcgta tttttcaaca attgaagaaa tctgtgcatt tgcacaacag
    25501 caagcacaat ataaagaaaa ccaacgtaca gttacttctt atcatgaaga gcaattagtg
    25561 acagctgacc ggctgcgtca attagaaaat atccagctaa ctgagacatt cccagataca
    25621 gaagagatca gccaacagtt agaagaaata agacgtatga tcgaaataaa gcaagaaaag
    25681 atatacggtt tacaagaaca aaaaattagt aatcaaaaaa tctacgatga atgtctttcg
    25741 atttatcaca caagccagac gaaattagat gagcttacgc aattacagca gctttcgcaa
    25801 acattcaacg gagaaaatcc taagaagact agtttggaac ggtatgtgct tcaggtttat
    25861 cttcaagaag tgttacaagt agcaaatgat catctccaac gtttaacgaa aaatcgttat
    25921 caatttgagc tagcggatac cattggcagt tatcgaggga aaaccggatt agaaatcaat
    25981 atctatgatg atcaggcagg tatgtctcga agtgcgcata ccctgtctgg cggtgagagt
    26041 tttattgcag cactttcttt agcattagct cttgccgatg tgatccagac acaagctggt
    26101 ggtgtagcaa tcgatgcatt gtttattgat gaaggatttg ggtcattaga tgaagaagct
    26161 ttggaaatgg caatggaagc tttagaaacg atcgaaagtg aaggaagaat gatcggcatc
    26221 attagtcatg taagagaatt gaaagaacga gtattacaac aaataagaat tgatacagaa
    26281 ggtagcggac aaagcaaaat acgctatcaa cttggataaa aagggagatt ggtaactatg
    26341 aaatggagta ttccagaaaa agtcattgca cgtggacgtc aatacttgca agaaggccga
    26401 gtgttatcgg ttgtccctga ccaagaagaa aacgtgtggc atgcagaagt cttgggcagt
    26461 gaattgtata tggttgattt ggatggtaca gcaaaagaga tagattactg ccaatgtccc
    26521 tattgggagg aacataaata ttgtaagcat acagttgctg tggaacttta tttacggtcg
    26581 aaaaatctat ctcgtatcat gaaaaaagac cagccaatgc tagaaccggt aaaagcaaca
    26641 agtgagggag aaatcattgc aaaaggtttt tctcgtctaa aaacacaaaa caatcctcaa
    26701 gcggtgcaac ctttgattat tgaataccaa gtagaaacga ttgagactaa tcagtatcac
    26761 ccagagcttt ctattttggc actttacttg cgtatcggtt cattggcatc accgaaaaaa
    26821 acatatatcg taaaaaacat ctatgatttt ttacaagctt acacagaaaa agaaacttac
    26881 actgttaata aacagtacca gtttcgtcta gataaacggg cgtttcaaaa agaagatcaa
    26941 aaaatactca cgcatcttgc aggaagtgct cagacgcatc aattattagg tacgaacggc
    27001 ttacaagtca aaggaaaact agataaaaga tatctgcttc tcccagtaga acaagcccgc
    27061 ttcctgttag agcagatgaa tcagactaca cgtttgcatc tgcagataaa tgaacaaaac
    27121 gatcaaggaa tacaattttc cgatcaaaac aaacctttat cattcaaagt ggaaaaattt
    27181 ggagaagatt atttgctgca agcattgaat gattttgatt ttttctttat gcattatcag
    27241 tggggagtta tccaagggac attttattct ctgacgaaat atcaacaaac ggtttatcaa
    27301 acttggaaac aattgattcg ccgattggag aaaccagaag tagtgttcaa gaaaaaagaa
    27361 ttaccgtctt tgtttaaaga gattatccct ctgctgtcag agatcggcga cgtagctatt
    27421 gcccctgcag tagaagagga agtagcagat atccccgtcg aatttatttt ctttttccga
    27481 aaagcaaaag gaaaaatcca agctcgagtc gatttcgtct atggtgaagt catctattcg
    27541 actgacccga agcatgaggt ctcgacagaa caggcttttc aggtgttacg tgacacagta
    27601 gaagagaaac gagtacttga tctattcaga atgtatcgct accagaaaaa tgaaactggt
    27661 tatgaacgtc cattgccaag cggggaagaa ctatatgcct ttttccgcac agaactatct
    27721 gtcttccgtc agtttggtga agtcagactt ggaagaaaat tgcgagagtt gtatttagat
    27781 gcgcataaac atcaaccgaa aatcgaagta accgagaccg gttcatggct cgatattcga
    27841 ttcgatgtga cagggataga ggagcaagaa atcgatcatg tcctgcaaag cttgctgaga
    27901 aatgatgctt tttatacatt agaaaatggt caggttcttt cttttgattc agaagaattt
    27961 caacaaacaa gccaagtgtt gcaacaatta cgggaatcga tacgtacaga agaaggaacg
    28021 atccatgtac ctaaaaatca aggattgatc attcaaaatc aattggaaaa aagcaatgct
    28081 acttttagtg aatcgttcca aacgatggta caagatctca ttcatccaga aagataccag
    28141 gcacagcttc ccaaaggatt gaatgcaacg atgagagatt atcaaaagca aggttttcga
    28201 tggttgaaga tgttaggtca ttatcagttt ggcggtattt tagccgatga aatgggactt
    28261 gggaaaacac tacagacaat tgccttttta ctttcggaaa aagaagaacg gaaaagcttc
    28321 tctgctttga tcgtagcgcc tgcgagctta atttacaact ggcaggcaga ggtgagaaaa
    28381 ttcgcccctt ctttaagtat ccaagtaatc aatgggaata aaaaagaacg tgaagaatta
    28441 ctggctaaag acacagatat ccgagtgact tcttatgcca gcttaagaca ggatctagct
    28501 aattatcagt cgcaaaaaat tgattatttg attcttgatg aggcacaaat ggtcaaaaat
    28561 agcagtacga aaactgcaca agcattgaga gaattagctg tacctcagcg gtttgcactg
    28621 agtgggacac caatcgagaa taatttagaa gaattgtggt cattgtttgc aacgattatg
    28681 ccaggatttt tcccgactaa aacaaaattc agggaacttg ccgcagaaga aattgcgcaa
    28741 atgattcgac cgtttatttt acggcgagat aaacaaactg tgttgaaaga cttgccggaa
    28801 aaaacagaga tgaatctata ttctgcactt acagaagaac aaaaaactgt ttatttagct
    28861 tacttgcgtc aaatgcgtga agaaatcaca tcaatggatt ctgaagcatt caagaaaaac
    28921 cggatcggga tacttgctgg tctgacaaga ctgcgacaaa tttgctgcga tcctcgtctg
    28981 tttattgaag attaccaagg cggttccggc aagctcgaac aagtaaaaga tctactggta
    29041 gctgccaaag agaacaaacg aagagttttg ctgttttctc aatttacagg gatgctgact
    29101 atcttgcaag aagagttagc cgagctaggg atctcgacat tttatttaag aggcagtacg
    29161 aaaccacaag atcggttaag tatggtagac gcatttaatg ctggcgaaaa agatgttttt
    29221 ctgatttcct taaaggctgg gggaactgga ttgaatctca cgggagcaga tacggtcatc
    29281 ttgtatgacc tttggtggaa tcctgccatt gaagaacaag ctgctggacg tgcacatcgg
    29341 atcggacaaa aaaatgtggt agaagtgtgg cgtatgatct ctgaaggaac gattgaggaa
    29401 cgcatggatt cactccagca agaaaaacgc gaactgttcc aaaaagtgat ccaaggtaat
    29461 gaagaacagt tgacgaaact gactgaagaa gacatccgca tgattttaag tgtaggagaa
    29521 atcgaggagt aagagactcg aaaaagcgtt cagtaatggg taagaaagcc tttctaaaga
    29581 agcgattgtt tatttgattt aaaaaatagc aaggaggctg ggattccatt ttatcccagc
    29641 ttccttgcta tcattttttt atttctattt ttaaaggtta tacaaagatt gtcttcattg
    29701 tctctaacag ctgatcaaaa gaagaaatct cgatatcgca aattggagtc tgttcaattt
    29761 tgcgttctcg atggttgaac caaagcgctt gccagttagc actttttgca cctagaacat
    29821 cattgtcgta attatcgcca acgtataagg tctcttctgg aagcatatga aattctttct
    29881 cagccagctg aaaaatctct ttttctggtt tttggaaacc tgttgcttga gaaatgagca
    29941 tattgcggga aggaatccaa ttgttcaatt gaagttgctt cagttttttt gtctgatggt
    30001 cagtcggccc atttgtgata attcctaatg ggacattctt ttccttcaag aaatcgaggg
    30061 tttttttgac ctcctcatgc aagcagatat tatcaagttc ttcctcgtaa attttttgaa
    30121 ataagaggcc atcttcttcc gtaatatgag ggtagtctaa atcttttagt gattggctga
    30181 tccgatgtgc tcgcatatat tctagtgtcc aatctcctgc cattactttt gggaagtttt
    30241 catcactatg atggcggaac cggatatata gtggatgcat atctgcatct gaaacaagcg
    30301 gaacgactct tttgaccgcg tttcgaaatg gctgctgctg atcatacatc gtatcatcaa
    30361 catcaaacac aactgattta atcaaaattt tacacgcctt tcggttttca ttgatttttt
    30421 cacaaatcct tgactattgt aacagaaaaa attgtctaaa aaagctgata aataaaggtt
    30481 tttcttacta tatttctatt tccttgacag aataaggttt ttatatttca gtttttttca
    30541 ctaaaaatcg tgaaacacgt caataagttt gatgaacaaa ttaatcatta tggtagaagt
    30601 cgattgattt attttaatgc aatctctgtg gaattttcga aagatttatt tttttaatac
    30661 agtctcaata taactattca aacataaaat aacgttattt gatttatttg tttatagtaa
    30721 attttattta gtaa
//
LOCUS       DADQCX010000029        29986 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.029, whole genome shotgun sequence.
ACCESSION   DADQCX010000029 DADQCX010000000
VERSION     DADQCX010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.029"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..2414)
                     /locus_tag="J8R83_001194"
     CDS             complement(51..2414)
                     /locus_tag="J8R83_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HAZ9574331.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2862..3083
                     /locus_tag="J8R83_001195"
     CDS             2862..3083
                     /locus_tag="J8R83_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574332.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3191..3538)
                     /gene="rbfA"
                     /locus_tag="J8R83_001196"
     CDS             complement(3191..3538)
                     /gene="rbfA"
                     /locus_tag="J8R83_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAZ9574333.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3565..5871)
                     /gene="infB"
                     /locus_tag="J8R83_001197"
     CDS             complement(3565..5871)
                     /gene="infB"
                     /locus_tag="J8R83_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAZ9574334.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5884..6195)
                     /locus_tag="J8R83_001198"
     CDS             complement(5884..6195)
                     /locus_tag="J8R83_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAZ9574335.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6192..6485)
                     /locus_tag="J8R83_001199"
     CDS             complement(6192..6485)
                     /locus_tag="J8R83_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAZ9574336.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6507..7682)
                     /gene="nusA"
                     /locus_tag="J8R83_001200"
     CDS             complement(6507..7682)
                     /gene="nusA"
                     /locus_tag="J8R83_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAZ9574337.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7706..8179)
                     /gene="rimP"
                     /locus_tag="J8R83_001201"
     CDS             complement(7706..8179)
                     /gene="rimP"
                     /locus_tag="J8R83_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAZ9574338.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8323..12675)
                     /locus_tag="J8R83_001202"
     CDS             complement(8323..12675)
                     /locus_tag="J8R83_001202"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAZ9574339.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12887..14596)
                     /locus_tag="J8R83_001203"
     CDS             complement(12887..14596)
                     /locus_tag="J8R83_001203"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAZ9574340.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14664..15932)
                     /gene="rseP"
                     /locus_tag="J8R83_001204"
     CDS             complement(14664..15932)
                     /gene="rseP"
                     /locus_tag="J8R83_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAZ9574341.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16093..16893)
                     /locus_tag="J8R83_001205"
     CDS             complement(16093..16893)
                     /locus_tag="J8R83_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAZ9574342.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16890..17702)
                     /locus_tag="J8R83_001206"
     CDS             complement(16890..17702)
                     /locus_tag="J8R83_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAZ9574343.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17897..18454)
                     /gene="frr"
                     /locus_tag="J8R83_001207"
     CDS             complement(17897..18454)
                     /gene="frr"
                     /locus_tag="J8R83_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAZ9574344.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18457..19179)
                     /locus_tag="J8R83_001208"
     CDS             complement(18457..19179)
                     /locus_tag="J8R83_001208"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAZ9574345.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19315..20196)
                     /locus_tag="J8R83_001209"
     CDS             complement(19315..20196)
                     /locus_tag="J8R83_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAZ9574346.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20295..21077)
                     /gene="rpsB"
                     /locus_tag="J8R83_001210"
     CDS             complement(20295..21077)
                     /gene="rpsB"
                     /locus_tag="J8R83_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAZ9574347.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21436..21915
                     /locus_tag="J8R83_001211"
     CDS             21436..21915
                     /locus_tag="J8R83_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAZ9574348.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22132..23223
                     /gene="phnW"
                     /locus_tag="J8R83_001212"
     CDS             22132..23223
                     /gene="phnW"
                     /locus_tag="J8R83_001212"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAZ9574349.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23216..24001
                     /locus_tag="J8R83_001213"
     CDS             23216..24001
                     /locus_tag="J8R83_001213"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAZ9574350.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24347..26038)
                     /locus_tag="J8R83_001214"
     CDS             complement(24347..26038)
                     /locus_tag="J8R83_001214"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAZ9574351.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26460..27407)
                     /gene="arcC"
                     /locus_tag="J8R83_001215"
     CDS             complement(26460..27407)
                     /gene="arcC"
                     /locus_tag="J8R83_001215"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAZ9574352.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27522..28541)
                     /gene="argF"
                     /locus_tag="J8R83_001216"
     CDS             complement(27522..28541)
                     /gene="argF"
                     /locus_tag="J8R83_001216"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAZ9574353.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28632..29861)
                     /gene="arcA"
                     /locus_tag="J8R83_001217"
     CDS             complement(28632..29861)
                     /gene="arcA"
                     /locus_tag="J8R83_001217"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAZ9574354.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8002 a         6451 c         5342 g        10191 t
ORIGIN      
        1 caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt ttattggtca
       61 agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc acgaatatag
      121 ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc ttgacttcct
      181 ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt tactacacgc
      241 atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat taaatgatgg
      301 ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa agcaaataag
      361 atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc acgcggatct
      421 tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat ttttagtttt
      481 gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga ttccgttcct
      541 gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca atcaatgatt
      601 ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg agcacgcgga
      661 tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt atccatgact
      721 gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc cttcttttct
      781 gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc ttgctggaag
      841 actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga aaggtcatgt
      901 gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg caagaatgat
      961 tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa gaacccttca
     1021 tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag ccattcatca
     1081 ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac ttgattcaat
     1141 cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt tttctcaatg
     1201 atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga gcctggtttt
     1261 tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg atcgattcca
     1321 ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat ttctctgatt
     1381 tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga tttcagccaa
     1441 cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg tacttggtgt
     1501 gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt ccatcctttt
     1561 ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc tgtcttcagg
     1621 cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt ttcagccata
     1681 acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca gccaagtccg
     1741 ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg gttggctatt
     1801 tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg attgataaag
     1861 acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc accaatcacg
     1921 acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga aagagagtat
     1981 ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg agaagcaatg
     2041 cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc ttccgttact
     2101 tctggataga tctctgtgta acttccatct aaataagcat tcgataccat gacttgtccg
     2161 ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat gactcggttc
     2221 aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat tggatgtttt
     2281 ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag ataaagttgc
     2341 ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa gtattcttta
     2401 ctagaataat ccatacataa cactcctttt cattattact cttattctag cgcagatact
     2461 cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat ctagccaaat
     2521 gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac attgatccaa
     2581 aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca tcatgcataa
     2641 tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct ggatcgagca
     2701 attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt caatatgtga
     2761 attggtatcc cagctactat gctaatttct acagggatta tccaaaattt ggatcgtgac
     2821 caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt cttttaactg
     2881 tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt ctagttactt
     2941 ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc ggtatcttga
     3001 tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa ttttttactt
     3061 ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg gaactcttag
     3121 gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca ggatttgcgg
     3181 gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg ttcccataga
     3241 caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt agattgtgcc
     3301 ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct tttttcttat
     3361 ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag tcccccgtaa
     3421 ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt ttgcgcaaaa
     3481 tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag ttagccataa
     3541 tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga taaatccttc
     3601 aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac attcataacc
     3661 cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt ggccttcata
     3721 gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat atccttctgt
     3781 tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac gaacgatcat
     3841 ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg cagtttcgat
     3901 ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt cagtatcagc
     3961 ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag cgttgctggc
     4021 tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga cgatttttac
     4081 acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg ctgaaccttg
     4141 tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca ggctttcaaa
     4201 taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg cacgttttgc
     4261 gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga aacggtcacc
     4321 tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc ctgcttcttt
     4381 atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat taccgacaac
     4441 gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca caggaccttt
     4501 acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg gatctgcttt
     4561 taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga tgttttggcc
     4621 gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag gaattaattc
     4681 atactcactt aattcttgca taacatgctg aggatttgca cctggtttat caattttatt
     4741 tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt caactgtttg
     4801 tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga tacttgctcc
     4861 acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag tgattggttt
     4921 accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg cttcgccgct
     4981 tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt ctacgtgtcc
     5041 cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt cttctgcctc
     5101 gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt ccatgccata
     5161 gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat tgaccatgac
     5221 accaagcata aataattttt taatgatttc tgctggctca cgatgaattt ttttcgcaat
     5281 atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac ggaatttgcg
     5341 tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt ttttattata
     5401 acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt tgttgttatt
     5461 gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc tgctggtatt
     5521 tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac cgctcccttg
     5581 accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg ttgtttcttt
     5641 tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt gtgcagcttg
     5701 ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac tgctagtaat
     5761 cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca cgacgtcttt
     5821 actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca tgcaatcacc
     5881 ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca ttattccgaa
     5941 taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata gctcaaagca
     6001 aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct cacttgcatc
     6061 ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg tcagttcttc
     6121 acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg ctttttgccg
     6181 attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt gacatagtca
     6241 agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc gagaattttt
     6301 ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc tcgtccaggc
     6361 atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat tcggaccatc
     6421 tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat tttcctttgt
     6481 ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac cgtttcattg
     6541 ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat tgcttcatca
     6601 tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt catgtcagat
     6661 tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc attttgtccg
     6721 cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca ggcctttgga
     6781 tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt tgcgatgaat
     6841 acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa ttcattgacg
     6901 attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc gatatttgga
     6961 tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat gctgacaatt
     7021 tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg caataggtct
     7081 ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac tcgggaaaca
     7141 taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc ttgtttagaa
     7201 agaactgcct caattttacc aagattgaca taaatataac gtttatcctg gcgttcgacg
     7261 attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat cgttctttct
     7321 gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat ccgtccaaaa
     7381 tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg attgattaaa
     7441 agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt tacttctttt
     7501 accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac gttttgtgct
     7561 tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc gatcacgatt
     7621 tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat ttctttactc
     7681 atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct tttgcaatat
     7741 tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc aatgtaagct
     7801 gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct actggttggt
     7861 ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct tttttcaatg
     7921 gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc ggatctggat
     7981 ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct tcgatatcga
     8041 taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct tttacaaatt
     8101 cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt tctgtgactg
     8161 tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta attccattaa
     8221 aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata agaactatac
     8281 catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca tatcgaataa
     8341 cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca tatattcgat
     8401 caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa atggaccgtc
     8461 ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga cagctctaaa
     8521 tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt tatacaaatc
     8581 aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca gcactgtcag
     8641 ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt tcattgcttg
     8701 tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg cacgtacaga
     8761 aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga cacgaagagc
     8821 catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt ttgaacaaga
     8881 atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg tttctcgcaa
     8941 ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt taaatgccat
     9001 cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac agccgattac
     9061 ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta accatacgtc
     9121 tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag gatgcgtttc
     9181 ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg tccctgtttt
     9241 ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata tccgcatcac
     9301 ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt gaagcatccg
     9361 aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat cgtgaatcga
     9421 gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg gatattggat
     9481 cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc ctggatgctg
     9541 gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt ctgcacttcg
     9601 aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg ttttgtcggc
     9661 gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata ctttcgtata
     9721 gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg gcactttgtc
     9781 tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt ttaagcgtgc
     9841 accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg taccatcttc
     9901 aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg gattaacttc
     9961 agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg aacctactag
    10021 atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa taaccgagaa
    10081 gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga tctcaggtaa
    10141 cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt catcttctga
    10201 acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt cgcagatatc
    10261 tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc ctaaaaagtg
    10321 aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac tatgacgatt
    10381 caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg catcttcttc
    10441 gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt ttccgatttc
    10501 taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt cttgctcgat
    10561 caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt ttgctcggtt
    10621 tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct tatcacaagc
    10681 tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta ttcgtgggac
    10741 gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt tcagtcctgc
    10801 ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag aatctccttc
    10861 tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca ttgcctcttt
    10921 cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc ggtgatgctg
    10981 ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt tgaattgagg
    11041 atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt caggaatacc
    11101 ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt gggctaccaa
    11161 aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg actttgaccc
    11221 tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca atggatgtcc
    11281 tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt tgactgcggc
    11341 tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt caaatacgac
    11401 gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga caccatcatc
    11461 tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc cagcactatg
    11521 tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc ggtgtcccca
    11581 ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg tactcatatt
    11641 gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt tgcgaggtgt
    11701 atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa acgtatcttc
    11761 ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa atacttgttc
    11821 atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat ctgtgatttt
    11881 caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga atacgtaccc
    11941 ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg ttggttcatc
    12001 ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt gctcttttct
    12061 ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca taaaggcttc
    12121 tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt gctgctcatc
    12181 cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact cttctactaa
    12241 tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg gcaagatgac
    12301 tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta gtggtgtatc
    12361 gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt catcgaatgt
    12421 ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag cgatagtcag
    12481 atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat gtagcgtaaa
    12541 ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag cagtaagcag
    12601 tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt caaataaatc
    12661 tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat tgatcgcatc
    12721 ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt ttacattaaa
    12781 aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat cagattgtca
    12841 aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat tcgccttggt
    12901 tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc atttcgccag
    12961 ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca gtgattctga
    13021 ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca tttctgtcat
    13081 caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc gtcaggcttg
    13141 tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc gcaattcctt
    13201 ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat aataaacgac
    13261 ttacaccgat accataacag cccataatca caaatttttc tcgtccattt tcgtctagta
    13321 cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt ccgatttcga
    13381 ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct tcttgtacaa
    13441 aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca tttttatagt
    13501 ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca taacggtctg
    13561 catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac tcagcaccta
    13621 gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat aaaaagtttt
    13681 tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca ggttgttcat
    13741 ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag aaatctgcta
    13801 cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc tgtgtttcat
    13861 gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca taatcacttt
    13921 cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat tcctttgagt
    13981 ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag ccacaacgct
    14041 tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa ctttcttccg
    14101 ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc aaaccgaagc
    14161 gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa ggtaatttct
    14221 tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga gttggtccaa
    14281 ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca tatgtttcgt
    14341 aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc atttctaccg
    14401 ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat acacgatttg
    14461 ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca gctcttagca
    14521 agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt ggaatcaaca
    14581 tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat cgtttgttat
    14641 tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt ccatgtaact
    14701 agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc ttctttttct
    14761 tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt cccgccatct
    14821 aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag cgccatcaaa
    14881 ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta catcatgaca
    14941 ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc tttgaaaatt
    15001 tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat aaaacctgta
    15061 ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc tacagatttc
    15121 ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc taatgtttta
    15181 cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc ttttccgtcc
    15241 acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc attaggcatg
    15301 atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa tgccagaatg
    15361 atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt ggtcagcata
    15421 cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct gatttctgtt
    15481 ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac ttctgtttcg
    15541 tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg gctcaattcc
    15601 atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc tacgatgccg
    15661 tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc atcatcccca
    15721 ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata tgttgtcccg
    15781 tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc gcggacgagg
    15841 attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac taatatacca
    15901 aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac ttgttttttg
    15961 tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc aaagacacca
    16021 atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca caaagaaacg
    16081 caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa acagcaaact
    16141 gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt ctttcacatc
    16201 ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg ctgaaaaaat
    16261 aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg ctgggtatag
    16321 caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg caccttcaat
    16381 cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc gaccaaccat
    16441 atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa cagccaagct
    16501 ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc tgacaagcac
    16561 aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg ttcctaaaag
    16621 aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa gaaagaaaaa
    16681 ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa ctccttcaaa
    16741 acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta ccgctaagat
    16801 tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa acaagactag
    16861 cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc atcttctgtt
    16921 ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc ttcttcaaga
    16981 tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact atatgcgatc
    17041 tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat cagctcagga
    17101 tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa ttcatcatcg
    17161 atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg gacagcagtc
    17221 acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc agtattgttt
    17281 tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa tacgttttca
    17341 taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa cgtatcaaag
    17401 aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt ccagttttca
    17461 gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt ttttgtgact
    17521 ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg acggttttgc
    17581 gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg tccatcggta
    17641 ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa aaaacgtaac
    17701 attctttttc ctcctatact taaaagattc ccactatctt aagtattata gcaatatcta
    17761 actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt ttttcttttt
    17821 ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga tccgcccctc
    17881 tgtttttatg attttattaa acttccaata attctttttc tttatcagca gcgatcttat
    17941 ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat ccgcgcaaat
    18001 catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc gcatcacgac
    18061 ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct ttagctaatt
    18121 cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt ccatcattgg
    18181 ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga agaatgctct
    18241 tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat gccatttggt
    18301 tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg ctagcgttcg
    18361 cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct tttttcattt
    18421 tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta cagttgttcc
    18481 gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat tgaagacaag
    18541 cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga cttgtaatcc
    18601 tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg catctacttt
    18661 cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa catctgcgcc
    18721 gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt tgccggtacc
    18781 gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac ggcgaatata
    18841 tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta cacccacgtt
    18901 ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac ccatgtaatc
    18961 agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga tatttccgcc
    19021 acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt cttggatgat
    19081 ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag cttctccact
    19141 caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc caatattttc
    19201 tattgccatt ttaccatact tagatgattt cgacactcta agactggttt ttcttgtttt
    19261 gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac agaattattt
    19321 tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga taccttcgcc
    19381 aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt atttttcaac
    19441 agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg ctttgaattt
    19501 cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt cgttcaatgc
    19561 ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt gtgattcgtt
    19621 tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa ctgtttcgtc
    19681 agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca agtatccacc
    19741 aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga ttttttctcc
    19801 gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg ttttgatttt
    19861 cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa tttcttttac
    19921 taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta cttcaacgat
    19981 tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa tgcggtcatt
    20041 tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt tttccatgtc
    20101 gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag tcatttcgcg
    20161 tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct gtgtgttttt
    20221 ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct ttgaaacagc
    20281 tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc tacgatttct
    20341 tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg atcttcacct
    20401 tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac ggcacgaatt
    20461 gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt tgtatcaacc
    20521 atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg ttctttacgt
    20581 gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc gcctaagaat
    20641 ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg tagaacttca
    20701 aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg tttttggata
    20761 gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta ttgtcctgca
    20821 cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac gaataatgct
    20881 acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac taatttaact
    20941 gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata tttcttcatt
    21001 tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag taattgtttc
    21061 atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct cttcttatct
    21121 tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga atgtggattt
    21181 gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc gcaagagcaa
    21241 atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa ttcaagaaaa
    21301 acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt ttaggtataa
    21361 aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg aaatctttcg
    21421 taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca agtcattgaa
    21481 gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta tggcgttacc
    21541 gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa ggcacctgat
    21601 gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga gactaggact
    21661 gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt cgaacgagtc
    21721 cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc atctgtttta
    21781 gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac gatcatggtc
    21841 atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca tccaactgaa
    21901 gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt ttttattttc
    21961 aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca ttttttattc
    22021 aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga tgttaacaag
    22081 agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca tatgtataaa
    22141 ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat gctgatcgat
    22201 cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa aaaattattg
    22261 gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg tagcggctcc
    22321 tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt actgatttgt
    22381 tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa actgaactat
    22441 accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac acagctgatt
    22501 gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac ttccggtatt
    22561 ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt gtttatagtg
    22621 gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg gattgatttt
    22681 ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt tgtacttgct
    22741 aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact tgatctatat
    22801 gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc ccctacccat
    22861 acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg aatcgaaact
    22921 cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac agagatgggg
    22981 ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct ttaccctaag
    23041 gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg atttgtgatc
    23101 tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg cgagatctat
    23161 ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa cgttaatgat
    23221 taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta tggctcctgt
    23281 ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca aagaaatccg
    23341 cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc tcccttctgt
    23401 caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg tggaggaatt
    23461 gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta ccttgaaacc
    23521 cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg gttccacgac
    23581 tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag aagggtattc
    23641 accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt ttccttatat
    23701 gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa tcaaagtcgg
    23761 agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag taggtgtaat
    23821 tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag agatggggaa
    23881 aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg ctgatatttg
    23941 tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga atccagaatg
    24001 acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa taagaacagc
    24061 caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc agatgcaagc
    24121 ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt gtcacagtcc
    24181 ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg tgttcattca
    24241 gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt tctcttttgt
    24301 ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac atcttatctg
    24361 gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact gcataaacta
    24421 gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga gcatagtatt
    24481 tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt tcgtattttt
    24541 ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact tcccagctgg
    24601 tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct ttttccaaca
    24661 ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct tcaaatcgaa
    24721 caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa tcgtggaaaa
    24781 tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa tcagggtttt
    24841 tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct tctaataaga
    24901 cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa ccaaatggaa
    24961 tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct ttcaactgtt
    25021 taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag tcgtaagtac
    25081 gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca ccgtctgact
    25141 tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct gcacctttat
    25201 cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc ttgtcattgt
    25261 agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag attttattga
    25321 attctttcat cgattcatca cggaaccatt gccataattg aatagcctct tcatcgcctt
    25381 cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct gtttcagcta
    25441 cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct ttaacagctt
    25501 cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt ccccagtcac
    25561 ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa ccgatcgaat
    25621 taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata ttaggagaag
    25681 acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa tgttcttttt
    25741 ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg aaaaagttca
    25801 agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt tctgctaaat
    25861 ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag gctggaaatg
    25921 caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact tgttccagtg
    25981 ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta ttattcatct
    26041 ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag cgacggcata
    26101 cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt gtcctaaaaa
    26161 aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa ttctccaagt
    26221 gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct agccaagaat
    26281 gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt gaattatatc
    26341 agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat ggcctaaagg
    26401 agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga cttaacaaat
    26461 taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat attttctaaa
    26521 gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc tgcctctact
    26581 ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt catttctgaa
    26641 acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata cacattgtct
    26701 actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt ttctgaagca
    26761 aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc tacaacagga
    26821 atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt ttcgatgaca
    26881 cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca tccacgtcca
    26941 gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc ttcttcttcc
    27001 gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt ttcatccaca
    27061 ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt cagtacttcg
    27121 cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac acatgtatct
    27181 aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa taggttaccg
    27241 acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat aaatttcact
    27301 aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc atccgtagac
    27361 aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc attcgtcctt
    27421 tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt gattttccct
    27481 caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg agggataaac
    27541 aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt ttctgcttgg
    27601 tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat ttcagtgatg
    27661 ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa agctggcaag
    27721 cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc catattgatt
    27781 tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc cattgatacc
    27841 catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc gtcggtaatc
    27901 atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat ttcttcttca
    27961 ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc acctgtgact
    28021 aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt gataccttct
    28081 actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt tggatgccat
    28141 tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc ctctaccatt
    28201 ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac tttagctgta
    28261 tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata ttcaggatgt
    28321 gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga tgttttttca
    28381 aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg ttttttcaag
    28441 tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt aaagtctttt
    28501 tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat tctcctttag
    28561 attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta agaccgccgt
    28621 caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca gcgtggacca
    28681 ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc atagctacga
    28741 agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg agcgattgcc
    28801 aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc tccattacca
    28861 gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc gtgtaagtta
    28921 tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac atccatctta
    28981 ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac cattgtaaat
    29041 acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa cactttttca
    29101 aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt cgcattagtt
    29161 cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc tccgccttcg
    29221 atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc aaatcttgga
    29281 tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc aaaagtcatc
    29341 ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa gtacaagttt
    29401 ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta tagactgcta
    29461 gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac catttcttgc
    29521 gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga tgcaatatga
    29581 gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc aatcgcttct
    29641 gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt ctttgcaaag
    29701 ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa cagacgatcc
    29761 ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa aactgtcttt
    29821 aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg cctccttctt
    29881 tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt tgtctcattc
    29941 aaaatgagac attcctcaca ttaatattcg ataattaaat aattaa
//
LOCUS       DADQCX010000030        29964 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.030, whole genome shotgun sequence.
ACCESSION   DADQCX010000030 DADQCX010000000
VERSION     DADQCX010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.030"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            210..1016
                     /gene="proB"
                     /locus_tag="J8R83_001218"
     CDS             210..1016
                     /gene="proB"
                     /locus_tag="J8R83_001218"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAZ9574355.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1013..2260
                     /locus_tag="J8R83_001219"
     CDS             1013..2260
                     /locus_tag="J8R83_001219"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAZ9574356.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2336..2680
                     /locus_tag="J8R83_001220"
     CDS             2336..2680
                     /locus_tag="J8R83_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574357.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2797..3123)
                     /locus_tag="J8R83_001221"
     CDS             complement(2797..3123)
                     /locus_tag="J8R83_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574358.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3738..4940)
                     /locus_tag="J8R83_001222"
     CDS             complement(3738..4940)
                     /locus_tag="J8R83_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9574359.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5057..5572
                     /locus_tag="J8R83_001223"
     CDS             5057..5572
                     /locus_tag="J8R83_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9574360.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5771..6217)
                     /locus_tag="J8R83_001224"
     CDS             complement(5771..6217)
                     /locus_tag="J8R83_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAZ9574361.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6264..7742)
                     /gene="msr"
                     /locus_tag="J8R83_001225"
     CDS             complement(6264..7742)
                     /gene="msr"
                     /locus_tag="J8R83_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAZ9574362.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8096..8725)
                     /locus_tag="J8R83_001226"
     CDS             complement(8096..8725)
                     /locus_tag="J8R83_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAZ9574363.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8709..9173)
                     /locus_tag="J8R83_001227"
     CDS             complement(8709..9173)
                     /locus_tag="J8R83_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9574364.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9660..10928)
                     /locus_tag="J8R83_001228"
     CDS             complement(9660..10928)
                     /locus_tag="J8R83_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAZ9574365.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11159..11896)
                     /locus_tag="J8R83_001229"
     CDS             complement(11159..11896)
                     /locus_tag="J8R83_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9574366.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11963..12532)
                     /locus_tag="J8R83_001230"
     CDS             complement(11963..12532)
                     /locus_tag="J8R83_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAZ9574367.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12660..13532
                     /locus_tag="J8R83_001231"
     CDS             12660..13532
                     /locus_tag="J8R83_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9574368.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13874..14746
                     /locus_tag="J8R83_001232"
     CDS             13874..14746
                     /locus_tag="J8R83_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9574369.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14743..16701
                     /locus_tag="J8R83_001233"
     CDS             14743..16701
                     /locus_tag="J8R83_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9574370.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17033..17884)
                     /locus_tag="J8R83_001234"
     CDS             complement(17033..17884)
                     /locus_tag="J8R83_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9574371.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18007..18474
                     /locus_tag="J8R83_001235"
     CDS             18007..18474
                     /locus_tag="J8R83_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAZ9574372.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18737..19219)
                     /locus_tag="J8R83_001236"
     CDS             complement(18737..19219)
                     /locus_tag="J8R83_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9574373.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19319..20182)
                     /locus_tag="J8R83_001237"
     CDS             complement(19319..20182)
                     /locus_tag="J8R83_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9574374.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20780..21655
                     /locus_tag="J8R83_001238"
     CDS             20780..21655
                     /locus_tag="J8R83_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574375.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(21800..21952)
                     /locus_tag="J8R83_001239"
                     /pseudo
     CDS             complement(21800..21952)
                     /locus_tag="J8R83_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(22220..23551)
                     /locus_tag="J8R83_001240"
     CDS             complement(22220..23551)
                     /locus_tag="J8R83_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574376.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(23700..24413)
                     /locus_tag="J8R83_001241"
     CDS             complement(23700..24413)
                     /locus_tag="J8R83_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9574377.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            24588..26012
                     /locus_tag="J8R83_001242"
     CDS             24588..26012
                     /locus_tag="J8R83_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9574378.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            26311..27018
                     /locus_tag="J8R83_001243"
     CDS             26311..27018
                     /locus_tag="J8R83_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAZ9574379.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            27005..27328
                     /locus_tag="J8R83_001244"
     CDS             27005..27328
                     /locus_tag="J8R83_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAZ9574380.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(27417..28454)
                     /locus_tag="J8R83_001245"
     CDS             complement(27417..28454)
                     /locus_tag="J8R83_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9574381.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(28775..29758)
                     /locus_tag="J8R83_001246"
     CDS             complement(28775..29758)
                     /locus_tag="J8R83_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAZ9574382.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
BASE COUNT         9132 a         6031 c         5324 g         9477 t
ORIGIN      
        1 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
       61 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tgcaagttgt
      121 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
      181 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
      241 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
      301 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
      361 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
      421 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
      481 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
      541 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
      601 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
      661 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
      721 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
      781 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
      841 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
      901 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
      961 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
     1021 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
     1081 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
     1141 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
     1201 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
     1261 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
     1321 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg atcggcatca tttacgaatc
     1381 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
     1441 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
     1501 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
     1561 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
     1621 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
     1681 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
     1741 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
     1801 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
     1861 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
     1921 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
     1981 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
     2041 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
     2101 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
     2161 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
     2221 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
     2281 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
     2341 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
     2401 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
     2461 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
     2521 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
     2581 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
     2641 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
     2701 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
     2761 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
     2821 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
     2881 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
     2941 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
     3001 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
     3061 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
     3121 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
     3181 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
     3241 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
     3301 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
     3361 acctcttggt aaacggcgtt caatcagctg accctcggta ttagctcaaa aaacggtaaa
     3421 atatgagaag ctatttttcc gttttgtttc tctaatactt aggataaaac gctgatttta
     3481 caacctctgt taaacggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa
     3541 aatatgagga actatttttc cgtttgtttc tctaatactc aggacaaaac gctgatttta
     3601 caacctcctg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3661 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3721 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3781 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3841 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3901 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3961 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     4021 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     4081 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     4141 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     4201 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4261 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4321 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4381 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4441 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4501 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4561 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4621 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4681 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4741 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4801 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4861 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4921 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4981 tgtcaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     5041 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     5101 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     5161 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     5221 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5281 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5341 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5401 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5461 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5521 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5581 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5641 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5701 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5761 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5821 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5881 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5941 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     6001 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     6061 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     6121 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     6181 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6241 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6301 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6361 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6421 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6481 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6541 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6601 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6661 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6721 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6781 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6841 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6901 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6961 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     7021 tccagtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     7081 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     7141 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     7201 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7261 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7321 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7381 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7441 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7501 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7561 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7621 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7681 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7741 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7801 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7861 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7921 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7981 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     8041 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     8101 cgaacatagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     8161 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     8221 ccaactgatc tgcttcgaat ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8281 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8341 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8401 ttggcatctt ccctgattcg taagcttggt tgtagatttc ttcgccatat tcgtaacatt
     8461 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8521 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8581 gtttcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8641 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8701 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8761 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8821 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg cttgattttc
     8881 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8941 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     9001 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     9061 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     9121 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     9181 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9241 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9301 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9361 attattgatt cttatcaaac tatagaagat agctcttctg cagtagataa ttttacaccg
     9421 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9481 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9541 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9601 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9661 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9721 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9781 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9841 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9901 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9961 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
    10021 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
    10081 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
    10141 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
    10201 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10261 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10321 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10381 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10441 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10501 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10561 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10621 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10681 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10741 gaaattgtat tttctgagac agtagctgac tgcaaagtac tttctgtatc gttttcaatt
    10801 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10861 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10921 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10981 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt aataaatttg
    11041 ctttttctgc ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    11101 atggtcgttt gaataactat ttaacaagta attctctctg gatattatcc gttatggatt
    11161 atacttcctg tgtcgtcgga cggataatca tgttgctgac agacatccgg tctggcgttt
    11221 ctatcgcaaa tgctacagca gaagctatat cttcagatgt taatccccat tctttttgcg
    11281 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11341 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11401 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11461 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11521 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11581 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11641 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11701 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11761 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11821 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11881 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11941 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    12001 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    12061 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    12121 catttttctt gatgtggatt ggctttactg acaagcctct tcgttctttt ggatcggtta
    12181 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12241 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12301 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12361 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12421 gcgctgctaa aggctcttcg ttttccgctt ggatctgatg gatcacttca aagagcggat
    12481 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12541 ctccttttat ccttacttta taacggacgg cttatgatgt ctaatactta taaaacatac
    12601 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12661 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12721 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12781 aagaacttgg tgtgacactt ttcactcgag gctcccgaga gatacagttg acggattctg
    12841 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12901 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12961 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    13021 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    13081 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    13141 cccaagatcg ttggggactt ttgatacatc ggaatcatcc tttagcaaag caaacagtca
    13201 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13261 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13321 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13381 atgggatcat caatacttat gggacggaaa aagtattcat cccactcgat ccgccattac
    13441 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13501 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13561 ttttaacaac gaataagtta agcaaaagat ccaatgatta aataacataa gtttcttaat
    13621 ttgttccttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13681 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13741 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13801 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13861 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13921 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13981 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    14041 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    14101 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    14161 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    14221 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14281 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14341 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14401 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14461 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14521 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14581 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14641 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14701 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14761 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14821 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14881 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14941 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    15001 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    15061 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    15121 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    15181 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15241 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15301 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15361 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15421 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15481 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15541 gaaaacaaag caaaaacagc ttccttgatg ttagcagcag cttttgcttc attctttact
    15601 ggtgtaacag aaccacttga attctcattt atgttcgttg cttggccatt atatgtcttg
    15661 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15721 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15781 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15841 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15901 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15961 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    16021 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    16081 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    16141 ttcgttgcag atgagatggc aaaactacat ggtggtgctg caacacgacc tgcacaaaca
    16201 aacaccgtgg ttaaaacaga aacatttgcc ggtggaacga tcgaacaaga tatttacgct
    16261 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16321 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16381 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16441 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16501 ttatatgtaa aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16561 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16621 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16681 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16741 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16801 gccaactccg cggtaataag tccagccaaa cgtaacatat gaagagctat tttttatttg
    16861 actcttctta ttacttgatg cagaacagct tttttacaac ctctgataaa cggtgttcaa
    16921 aaaccagttt atcggtatga agtcaaattt atgcaaaaat gtggaaagcc attttcacaa
    16981 aatttttctt catactcaaa actaatcggc tttttcacaa cctctttata cattattcct
    17041 gatccaatat ttcttttaat gctgcttcaa gagaagttaa tggttttccc aatacttttt
    17101 ctaaatcatc agaggaaata gctaactgat cctttttaat atcatgttgg atcgctaaaa
    17161 acatgtcagc tgcttcttga gggaatccgg cttcttttag attttcgaca aacgctgcat
    17221 cacttgcttc aataatttct aactttttac ctgtcgcacg ctctaatgcc ttggctaatt
    17281 cttcatagtc agttagattg ccggataatt ctaagatttc tggagagtca ctttctacta
    17341 gtacttttgc tgcagcttct gcatattcac gtttcaatgc ccaacctgtt tttccatttc
    17401 ctgcagcata aacgaattga ccagttttta aagcctgccc aatgataggt aattcattct
    17461 ctacatacca attattccgt aaaaatgtat gggaaatacc tgaatcctta atcatttttt
    17521 cagtgaattg gtgatctggc gctaatacac tgatcgagtg atcggcatct gcaaaacttg
    17581 tataagcgat ataagatacc ccagctgctt gtgctgcctt cactacattc ttatgttcgg
    17641 cttgacgatt tcctggaacg ccagagacaa aaagcaatcg atctattcct ttcaacgctt
    17701 ctttcattga gtctaaatca tcataatcac caatacgtat attaaatcca gcttctttca
    17761 gtgcttctcc tttttcttca ctacgtacta gtacatagat ttcattttgt ggaaccatct
    17821 tttttaagaa ttccagcgca taaccaccaa aacctccagt tgctcctgtt actaaataat
    17881 gcatatttgc cactccctat tctttttatt tgttaagatt tacagctgta catttataaa
    17941 ttacaccttt atcataaaga gtgtggtaag ataagtcaag caaaaaaaat gaaaggatga
    18001 caactgatga agtattctct gcaatttagt gatgcaatcc atgtacttgc ctatattgaa
    18061 atgtttcaag atacccgatc actttctagt gagatgattg ccagtagtat cgaaacaaat
    18121 gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat ccggtttgat ctttacaaaa
    18181 accggaaaac cgcagccttc ccttgccaaa agtccagatc agatttcttt actagatgtc
    18241 tatcgcagca tcgaaggtaa tacacagctt atccaagtcg atccaaaaac aaatccaaat
    18301 tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa gctacgctcg gctgcagaaa
    18361 aaggcagaag aagaaatggc taagatcaca cttgatagtc tgatacataa aatagccgtt
    18421 ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag agagattttt ataattctct
    18481 ctactgtgcc tgcatttttc tgatcggaat cgtctacata aattctttta ttctccgggg
    18541 gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct caggtcaaag cgctgaagtc
    18601 atgacgtctt gataaacggt gttcaagtag ctgaccctcg gcattagttc tgaaaaatgc
    18661 aaaatatgga aagctatttc ccatttttcc tctctaatgc tcaggtcaaa gcgctacttt
    18721 cacgacctct atattatcat ggtttattga ctaccggtat ccagatttct cccatatatt
    18781 tcccgttggt aactcccatt tcgactacag catttggacc cccaacatag gcgtaatctt
    18841 ctacttctct taaaacatgc ccaaaggccg tattcgtcaa atcatttctt aattcttcag
    18901 gcgattctgc taaagcgatt acaacaagat acgttccttt tgggaatggg atgattcggg
    18961 tagtgtttgg aacatcctga ctcgtttgaa caccgacata gtacatcatt ttcccgttat
    19021 agggttcgtt gactgtaaag aaataatgat tttcagcagc ttgtttcaat gcatctattg
    19081 ttccattacc gataactttt tgctcaaatg cttgtttctc tgcagccaaa ccgacaaaat
    19141 ccgtattgct actcttcaat tccacaccaa tacccgtcac cgtaaaatct ggtttttctt
    19201 cgatcctata ctttgccatt tctcccaccc tttctattat attaagttca tcttacataa
    19261 aattaaaggg aaatgacacg attacgctct tttttctagg gatattttta ttttttaact
    19321 atttttttgc tttcactgca atccaaatct cactgtaaac attactgaaa tcctctcccc
    19381 attttgtaaa agagatctcg ggagcttcga ctaactcata atctgaagaa ggaagccatt
    19441 ctgcatagat tttcccccaa gtatcttgta aagtttgggg aaatggccct ttattaggaa
    19501 aaatggccca agtgtgttct tctatagcaa gcatttctaa atcagcgtac ggattttctt
    19561 ttgtcgtagc aaagccaatc atgtgcatca aactgccctt ttcttccaag cgggctccat
    19621 caaatccata agaaacgttg attacttgat ttggatataa atctcctaac ttatgcatct
    19681 cttccctttg agtctccgtg atcgtctgcg ctaacttttg tatttcttga ttgactcctt
    19741 caaatttgac aggaactttt ttcgccacac ctgccacata aaactgttct ttcttttcga
    19801 tacgaaattc catcgatttt cctcctctga catcaataaa aaatgtcaag cgtggaaaag
    19861 atttttgtat gccgtatctg ctgatttctg aaggcagata tcctgaccaa tcacgaaaag
    19921 ctcttgaaaa accttcgact gtttcatatc catatctaaa cgccgtttct gtcactcttg
    19981 atccatctag gagatcgcga ttagccaaag ccaatctacg gtttttgata tagtccatta
    20041 gcgacatccc tgcaataaac gtaaagatgc gttttaattg atattcagag attcctgtat
    20101 tttcggctat tattttatag gaaagtcctt ctgtcaaatg ttcttcgatg taatcgatca
    20161 attggttcag atctttaagc atatttatct tcctccttgc ttgccttttt atcatattat
    20221 caaagaaagt caattacttg atgaatcagg aaccaattta gtcagatgta gaaaatgttg
    20281 tatggatcta aagaaaattc tcaagcagcg tttcgtaacg gataattggt attatctgcc
    20341 tatctatgtt ttacctttag aaaaataaat tttggggaag acacattcta agtaaacaaa
    20401 gcggtaaaaa tatcttttat tcccttagtt aatccgctta ctacctactg tacaaagcaa
    20461 attgttgttc aaactgctga tcagaacgct gcttggattt ttctttgcga tacatcatac
    20521 ctcttttatc aattggaaca attatttatt tctaacaaaa tcacttcatt tttgtcagat
    20581 aaataaaaaa caaaaaaagt tccatcttta aaacacgcta ttcttttact ttttctcaca
    20641 ttctctaaga aaagaaaagg agaatgaatt tttgacaatt cgagcaaaag tgattatcaa
    20701 atatgtaaaa tcagctactt ttttcttaaa cgtttcttta tactaaatat aaataagtgt
    20761 ttcatgaaag gagaactaga tgaataattg gcttgagtat tttcctgaaa acgttttgga
    20821 acgcggttac agctatcatc tgcacggttt tgtccgtcat ttgaactata caagcaagta
    20881 cttgtccgca acagtttctg gcacggaaga ttataaggta gtgatcactt gggatgaaaa
    20941 gaccaacatg acttgtgatt gtctatatgc catagaagga aaaaaatgca aacacatggc
    21001 tgctgtctta ttcgcttacg aagaacgtcc aataaaaaaa tccaactact cactttccga
    21061 actctcgtcc cttgtttcct ccgctagttc ctctcttgta cgggagcttt taacagagat
    21121 tcttatagaa catccgcaat ttatcgaacg cttcaaagtt aagatgccat ttcatgcaat
    21181 aaattattca gataaattaa caactatcat ccataaatac gatcatatta tcaagaaaaa
    21241 caaaaacagg aaaacagcga agttcatcat ggagatgcga aagttcatcc aagaagcagt
    21301 tgaatcgctc attcagcaaa atgcctatct tcccgcattc gaattgatca atgaagtgat
    21361 tgctactctc gaaacattct attgggagcc tgaggatgaa cgaacccttc ttctgataga
    21421 ggactgttat tatttatgga aagaattatt agcagaagca cctcatgcag aaaaaaggca
    21481 aatgttctct tggttcgtct gccaagtcga tcatactgac gcctcttatt caaaacgcta
    21541 ctccataaaa atcctgaaag aagactttcg ggaaaaagaa ttttctaacc aaaagaaaaa
    21601 aatagataaa aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt
    21661 aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt taaaaacacg
    21721 aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag tcatttgact
    21781 attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct gggtagattt
    21841 tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga ggttccactg
    21901 catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac cactctaatc
    21961 tttaaagata aatattaaaa taacgattaa taatattaac agtctttatt tttcaccacc
    22021 aaaaacctat ctttgcatat actaaataga cgtatataca cagataggtt tgtcttgtga
    22081 aaaataatga ttatccttac caaaaaatgt ttgtttttct acatgttcgt acttatcaaa
    22141 aaatatgatc cttattgaaa ttactggcta tttatattcc aacgacttct tgtgttaatt
    22201 tttgttatct catagtaaat tatgtttcat tttcacttaa tttagttgtc acgtgttcgt
    22261 caattcgtaa aaacggtaaa tatataaaca cacttgcggc tataattaat atttgtaaaa
    22321 cagctgctcg ccagtctccg gctgttgcta aaaatcccga tataactggt ggcgtagtcc
    22381 aaggaatttg cactactaca tgattaatta atcccacagc agttgcaaaa tatgctactg
    22441 tcaaagaaaa aatcggtgca agcacaaagg gaataatcag actgatatta aatacaatag
    22501 gcaatccaaa aataataggt tcgcttatat tgaatatagc gggagttacc gataatttag
    22561 caaagtcctt ataatctttt ctacgactga agataaatat tgcaatcaat aaagcaatcg
    22621 tatttcccga tccacccatt accgcaaagg tatctttaaa ggccatattg ataatatgtg
    22681 gaatttgctc tttgtttgca taagctgcca tattttcttg catattctga atcaaaaacg
    22741 gatctaacaa tgaacctgat attactgctt gatggatacc aaatccaaaa aatagattag
    22801 caatagatgt aattaacaaa aatcctggta aaccagttgt aattttactt aatggctctg
    22861 taactatcgt ggtaattagc ttatttatat ccatattaaa caattgaatg attataaatg
    22921 acaataaagc aaacgaggta atcgtaataa tgattgggat taatacatta aaagacttta
    22981 aaacagcggg aggaatattt ccggatagct gaatctgtag tttcttatta ttagaaagtt
    23041 taataaataa ttctgtagcc gctaatccaa caaatatacc tacaaacatt cctgaagctc
    23101 ctgtatagga tataggtatc acacccgtca cttcaacagc tttatccgca ttttcaggag
    23161 taaacatcat ctgcataggt gttaatacaa caaatgtcga aatagcaact aataccgctg
    23221 caatatgatt tgtataattt ctgcttgcac acatatgata agatactgct gctacaacta
    23281 ataatgtagt tatgcttaat gtaccattgg caattgaagt accaatttgt tgtaacgtgg
    23341 tcaatgtact agtatcgaca atttccccca tgaatcctgt tggttctaag atcactgaat
    23401 taataagtgt cacaaatcct gctaacatca taaatggcat aaatgtagca aacgcatctc
    23461 gcaaagttct taaatggatc tgattcccca acttagtcgc aactatacca aatttttcaa
    23521 atacaatgtc cttcctgcta cttttgccca tattttttct cctttatgct tattgtaatc
    23581 gattactttt tccacccaaa taatacatca cttatcaaaa aaagtaaata cttttaatta
    23641 aatatatata tcttttttag tataaaaaaa taagctctga aaaaataatt ttcccgagct
    23701 tatttttcaa caaaaacagc ttcaaaaaca aagtcttgat ataaatgtct cgataccgaa
    23761 tactcgaaag gtttaccaga cgatagagca acaactttgt ctatctcaat cataaattca
    23821 cctggatcta tttttaatat ttttgcgtca aattcattcg cagtatctcc tttgatacgt
    23881 atgtgcgaag tctttatttc cagacccagt tcatttgtga tataagcata tacagatttc
    23941 tttaaatgtt ttggttccaa gcctggtatg actgctaatg gcatgaatgt ttgctcaatc
    24001 gagtatggtt gacaatcaat aaaacggctt cgtacaatat tatatacata gtcttttaca
    24061 ctgatactta atttatcagc tacttttttc gatggaagtt caattgagaa agtatggatt
    24121 tctgaatcta cgtgttcttc accaaccacg ctaaacaaac cttcgtttgg accaagaact
    24181 cgtgagttat caattggtgt tctgacgact tcagtcccat acccacttct acttcgcaaa
    24241 actccttcgg aaacaagtaa gtctacgcct ttctttactg ttaacttgct tgtatgataa
    24301 ataactgcca attcatctcc tgtaggaagt ttctcaccaa ttttatactc tccatttaca
    24361 atttttttct ttatatctaa gtaaatttcc atatacttcg caattttttt caatggtgac
    24421 cctccaatca aaaacatatc ttcatctata ctttaacata aataaaccga taaaatccac
    24481 atcaaaatta tacacacaat aaaaaagata tatatattta aacaaaacta tttactttaa
    24541 gttgtaagcg gtgttatcat taagtggaaa caggaggtaa aaaaattatg acaactatga
    24601 aaaagctaac ttttccagat gatttttggt ggggttccgc ttggtcagct gagcaagcag
    24661 aaggaaaagg agaaacagga aaagcagaga ctatctggga tcgctggttt aaagaacaac
    24721 cttaccggtt ttatcaacga atcgattcct ctattacaac cgatcacatc catcaatata
    24781 aagaagatat agaactaatg aaaaaaactg ggcataactc ctttcgcgtt tctatttctt
    24841 gggcacgaat gtttccaaat ggcggtaccg gaaaagtaaa tcccaaagcc atttctttct
    24901 atcgaaaatt attttccgaa atgaataata acggaatcaa agtatttgcc aacttatatc
    24961 attttgacat gcctgctact cttcaagata aaggaggatg ggaatcacgt gaagtagttg
    25021 atgcttatgt tcattacgct gaaacttgtt ttaaagaatt tggtgactta gtttgtcatt
    25081 ggtttacctt caatgaacca cttgggccta ttttaggtac ttatcttgaa gattttcatt
    25141 atccaaacct cattgacttt aaacgcggag cgcaagcagc attcttcact atacttgcac
    25201 acgcaaaagc aatacaagta tttaaagaac tagctcttcc tagtaaaata ggcgttattc
    25261 taaatttgag tcctactttt cctcgtagtc aaaatcctgc tgatgtgaaa gcagcagaaa
    25321 tcgctgattt attttatacg cggagctttt tagatcctat ggttaaaggg aatttttcta
    25381 aaaagcttat cctgttatta caagaatata atcagcttcc tgaagattat acgaaagaag
    25441 atcttgtatg tatctacgaa aataccgctc aaattcttgg actaaactat tacgagccac
    25501 gtcgcgtcaa atctcgttct tctatggtgg atacatctag tccattttta ccagagtggt
    25561 ttttcgaacc acatatcatg cctggacgac gaatgaacga ataccgggga tgggaaattt
    25621 acgaaaaagg aatttatgat ttgtgcatgg atatcaagaa ccattatgga aacatcgaag
    25681 catttatctc ggagaacgga atgggcgttg cggatgaaga acgtttcatg gatgatacag
    25741 ggcaaataat tgatgattat cggattgagt atatcaaaga tcatcttgct tacttatgga
    25801 aggcaataaa tgaaggatgt aacattaagg ggtatcatct ttggacattt attgattgct
    25861 ggtcatggat caacgcctat aaaaaccgat atgggctggt ttcactcgac cttactactc
    25921 aaaaaagaac aattaaaaaa agtggcgaat tttacaagca attaagtgat acaaatggat
    25981 ttagatacga tgtagacttg ttagttgaat aatattctaa aattccactt gaagtgaaca
    26041 cattagaaaa caagaataat gagaaatacc aataacaaat actttttctt catacttcat
    26101 ttatacttgt cagtataaga gactgtgaca aatgtagtga tcctcagaag ttaggtctgg
    26161 aaatctaact tgagaagatt tttttaaact acgtccagtc ttttttattt gtttaaaatt
    26221 gaagttgaca agtcttcatt aaaaatttag aatattcaca agtttgacga caattatgaa
    26281 aatttatgtc gtgctaaagg agttttgtta ttggatgaaa agttagatat aaaaactgcg
    26341 atcaaagaca cgttacctac cgtttttggt tatatcggta ttggacttgc atttggtatc
    26401 gttgggaaag ctgccgggtt tcatccgctg gtcgtcacgt tgatgtccct gctgatctat
    26461 gctggttctg cccaatttat cacggtcagc atgcttgcta gccatagtcc actgctctcc
    26521 atcgttctct cgacctttct agtcaattcc cgaatgattc tgatgagtat gacgattgct
    26581 ccttatttca agaaaaatcg gctgcttcaa aatctgctga ttggcacatt gctgacagat
    26641 gaaagtttcg cactgggaat gaataaattg aactatactg gacaaaagtt aaactttcgt
    26701 tggatgaata cagctaattg gatttcttat ttgacgtggg tgggttcttc tcttgttggc
    26761 gcacttttag ggaattttat tactgatccg aaaaagtttg gtttggattt cgccatcgtc
    26821 gctatgttta tcgggttact ttatcttcaa gtcatttctg atagaaacac ctctaaacga
    26881 ttacagttga tcctgattgg tctcactttg attctggtat atgtcggact gatttttatc
    26941 ccaagtaact tagtgatttt agttgtaaca ctgattgggt gcggattggg ggtgtggatc
    27001 aaacatgcct tcttttgagt ttacattgct gactatttta ggttgtactt tagcaacttg
    27061 gctttctagg atcctaccat ttgtcttact gaaaaaattc gatttgccgc aaccgttgct
    27121 tgagtattta agttttgtcc cgatcgtcat tatgtctgct ttatggttca gcagtctatt
    27181 tacccaaaat atcggacatc tgccgcagat caatctcgaa aatgctttgg cttcagttcc
    27241 tacactttta gctgctattc tttcaaaaag cttattggtg atcgtcttgg taggaattct
    27301 ttccctttcg ttgattcgct tattataaat aaaaaaacaa gagcttatgg caaattactg
    27361 tcatgcgctc ttgtttttat caaagtcaaa taagaaaaaa atcggcgtat tcttgcttat
    27421 ccgttgaacg gaccactaac aacgactttt cctaatatat gtcctgtttc tacgtctttg
    27481 gttgcttgtt tcaagttctt cgcattcatc ccatctgaat agaccttgct caatgtactg
    27541 cggataatcc cttcatttgc taaagcagca atgtgcgcta aagcttctcc ttgcgtttcg
    27601 atttcatagt tatagtctgt tttagcgaac atatactccc agtcgaagct gatagattgg
    27661 tttttccaaa cacctatatc taacggctct ttgatcccta cgatcgttcc cacatgtcca
    27721 aatggtcgga caaggtgttt gatttgatca aagtagcggg taatatcgaa taatacagcg
    27781 acatactcta cttgatcgat tcctaattca cgaaaacttt tacttaagtc gtgatgataa
    27841 tcgattggat agtctacacc tgtttttttc agccattcaa aattcttcgg acttgcagtc
    27901 gcgtagactt ctaggccagc ccaatgcgct agttgattca aaatcgaacc gacgccccca
    27961 gctccgttga tcactaagat ttttttcccg cggttggcat tttcttctgg agtcagacca
    28021 aatttttcaa ataacaattc ataagcggtc aatgaggtca acggcaaggc tgcggcttct
    28081 tcatctgaaa gattttttgg tgcaagagcg acaatacgtt cgtcaaccag ttggtattct
    28141 tgattgcttc ctgctcttgt cgttgtacct gcgtaaaaaa cgcgatcgcc gacagaaaat
    28201 ttttgcactt catcacctac agcaacaact ttcccgactc catcaaaccc taagatacgt
    28261 aaagcatttc ttatcccgtt atcttggcga agtttcgtat cgacaggatt aacagatact
    28321 gcgttgactt ttaccagaag atcccgtgaa ctgggtacag gtatctgttc tttttcatca
    28381 ataaagcttt ttggatcatc gatcgacaac ccttcataaa aaccgactac cttcattaat
    28441 tccttttctg acatacgaat tcctccttag cttcatcaag ttggagcatc catacagttt
    28501 tcatttcaat atatatagta tgctatttgt tccactttta ttcatcataa ttattctctt
    28561 acttaaagta aactatttgc acttttttgg ttaaaaaaga ggttgcgaca agacttttgt
    28621 cacaacctct tttaaacggt gttcaatcaa ctgaccctcg gtattcgctc aaaaaacgac
    28681 aaaatatgag gagctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt
    28741 cacgacctct aattcacggt gttcaagcaa gaaatcattg ttcactgaaa agcgttggat
    28801 gttctttttc aaaggtgtct aagatctctc gtacttcatc agtagatttc gtattcatca
    28861 actgaactcg caagtcattt gctcctggaa atcctttgat atagatttta aagaaacgat
    28921 gtagtcctgt gatggaacgc gggatgattt ctgaataatg atcttgcaga tctagttgca
    28981 gacgaagtag tccgatcagt tctttttctg tatgttccct cggttctttt tcaaatgcat
    29041 aaggattctt gaaaatcccc cggccaatca tgatgccatc tacgccatat ttttcggcca
    29101 attcttctcc tgtctggcga tctgggatat ctccgttgat cgtgatcagt gtttgcggag
    29161 cgatttggtc acgtaaagca atgattttag ggatgacttc ccaatgtgca tctactttac
    29221 tcatctcttt acgcgtacgc aaatggacag aaagattggc tatatcttga tgaagtaggt
    29281 gactgatcca ttcttccatc tcagacattt ccgtatagcc gatacgcgtc ttgacgctga
    29341 caggcaaacc gccagcttta gccgcttcaa tcaattgtgc cgctacttct gggcgaagga
    29401 tcaagccact gccttttcca cgttctgcta cattagggac tgggcagccc atgttgatat
    29461 cgattccttg gaagcccatt tctgccatag caatgctcat ttctctaaaa aattctggct
    29521 tgtctcccca aatatgggca accatcggct gttcatcttc tgtaaaggtc aatcttcctc
    29581 gtacactgtc ttttccatct ggatgacaga aactgtctga gtttgtaaac tcagtaaaga
    29641 agacatccgg tgctgctgca tgctttacga catggcgaaa tacaacatct gttacatctt
    29701 ccattggtgc taaaacaaaa aaaggctttg gcagctcttt ccaaaaatta gtagtcattt
    29761 atttgttact ctccattcta tcaagcagtg aagtcgcaat ctttctcaaa aacattgtca
    29821 ttatactagg aaacaaaaaa agaagcaaag tgaacagctt aaaagatgtt tctgattgag
    29881 caaaaaaaga ctgtgacaaa aatcttatca caattccttt tccggaataa atggtgttca
    29941 aaagcttgca tctgcggtaa taag
//
LOCUS       DADQCX010000031        28445 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.031, whole genome shotgun sequence.
ACCESSION   DADQCX010000031 DADQCX010000000
VERSION     DADQCX010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.031"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(218..1015)
                     /locus_tag="J8R83_001247"
     CDS             complement(218..1015)
                     /locus_tag="J8R83_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAZ9574383.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(1012..2196)
                     /locus_tag="J8R83_001248"
     CDS             complement(1012..2196)
                     /locus_tag="J8R83_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAZ9574384.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(2221..3468)
                     /locus_tag="J8R83_001249"
     CDS             complement(2221..3468)
                     /locus_tag="J8R83_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAZ9574385.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            3683..5428
                     /gene="dnaX"
                     /locus_tag="J8R83_001250"
     CDS             3683..5428
                     /gene="dnaX"
                     /locus_tag="J8R83_001250"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAZ9574386.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            5448..5762
                     /locus_tag="J8R83_001251"
     CDS             5448..5762
                     /locus_tag="J8R83_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAZ9574387.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            5787..6383
                     /gene="recR"
                     /locus_tag="J8R83_001252"
     CDS             5787..6383
                     /gene="recR"
                     /locus_tag="J8R83_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAZ9574388.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            6447..7091
                     /locus_tag="J8R83_001253"
     CDS             6447..7091
                     /locus_tag="J8R83_001253"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAZ9574389.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            7106..7435
                     /locus_tag="J8R83_001254"
     CDS             7106..7435
                     /locus_tag="J8R83_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574390.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            7449..8387
                     /gene="holB"
                     /locus_tag="J8R83_001255"
     CDS             7449..8387
                     /gene="holB"
                     /locus_tag="J8R83_001255"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAZ9574391.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            8423..9247
                     /locus_tag="J8R83_001256"
     CDS             8423..9247
                     /locus_tag="J8R83_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAZ9574392.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            9240..9587
                     /locus_tag="J8R83_001257"
     CDS             9240..9587
                     /locus_tag="J8R83_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAZ9574393.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            9656..10528
                     /gene="rsmI"
                     /locus_tag="J8R83_001258"
     CDS             9656..10528
                     /gene="rsmI"
                     /locus_tag="J8R83_001258"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAZ9574394.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            10637..11758
                     /gene="dinB"
                     /locus_tag="J8R83_001259"
     CDS             10637..11758
                     /gene="dinB"
                     /locus_tag="J8R83_001259"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAZ9574395.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(11812..12414)
                     /gene="nrdG"
                     /locus_tag="J8R83_001260"
     CDS             complement(11812..12414)
                     /gene="nrdG"
                     /locus_tag="J8R83_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAZ9574396.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(12729..14918)
                     /gene="nrdD"
                     /locus_tag="J8R83_001261"
     CDS             complement(12729..14918)
                     /gene="nrdD"
                     /locus_tag="J8R83_001261"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAZ9574397.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            15244..16011
                     /locus_tag="J8R83_001262"
     CDS             15244..16011
                     /locus_tag="J8R83_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574398.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            16001..18043
                     /locus_tag="J8R83_001263"
     CDS             16001..18043
                     /locus_tag="J8R83_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574399.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            18324..18473
                     /locus_tag="J8R83_001264"
     CDS             18324..18473
                     /locus_tag="J8R83_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAZ9574400.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            18484..19998
                     /gene="dltA"
                     /locus_tag="J8R83_001265"
     CDS             18484..19998
                     /gene="dltA"
                     /locus_tag="J8R83_001265"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAZ9574401.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            19995..21200
                     /gene="dltB"
                     /locus_tag="J8R83_001266"
     CDS             19995..21200
                     /gene="dltB"
                     /locus_tag="J8R83_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAZ9574402.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            21245..21478
                     /gene="dltC"
                     /locus_tag="J8R83_001267"
     CDS             21245..21478
                     /gene="dltC"
                     /locus_tag="J8R83_001267"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAZ9574403.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            21481..22749
                     /gene="dltD"
                     /locus_tag="J8R83_001268"
     CDS             21481..22749
                     /gene="dltD"
                     /locus_tag="J8R83_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAZ9574404.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            22890..23972
                     /locus_tag="J8R83_001269"
     CDS             22890..23972
                     /locus_tag="J8R83_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAZ9574405.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            23972..24775
                     /locus_tag="J8R83_001270"
     CDS             23972..24775
                     /locus_tag="J8R83_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAZ9574406.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            24845..25585
                     /locus_tag="J8R83_001271"
     CDS             24845..25585
                     /locus_tag="J8R83_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9574407.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            25596..26600
                     /locus_tag="J8R83_001272"
     CDS             25596..26600
                     /locus_tag="J8R83_001272"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAZ9574408.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(26645..28408)
                     /locus_tag="J8R83_001273"
     CDS             complement(26645..28408)
                     /locus_tag="J8R83_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574409.1"
                     /translation="MLFLTGIAYFFYFIFSPADSNQMKEIKDSWVFYTKDDPDFKFDS
                     KYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEES
                     NPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQV
                     LTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALGFEAVSEDILSGILFEP
                     FVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAEL
                     PELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGI
                     YQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQH
                     IQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLI
                     LARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEHSFRETHAIENPLYRKI
                     YLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQ
                     EKDTFIDRITVQLSRNYPNPV"
BASE COUNT         8965 a         5036 c         5858 g         8586 t
ORIGIN      
        1 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
       61 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
      121 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
      181 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
      241 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
      301 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
      361 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
      421 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
      481 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
      541 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
      601 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
      661 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
      721 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
      781 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
      841 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
      901 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
      961 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
     1021 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
     1081 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
     1141 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
     1201 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
     1261 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
     1321 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
     1381 atactggctt ttaaaatcaa ttgccttatc taacgggaaa ggttgcacgc cttcgaccat
     1441 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
     1501 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
     1561 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
     1621 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
     1681 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
     1741 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
     1801 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
     1861 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
     1921 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
     1981 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
     2041 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
     2101 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
     2161 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
     2221 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
     2281 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
     2341 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
     2401 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
     2461 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
     2521 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
     2581 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
     2641 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
     2701 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
     2761 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
     2821 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
     2881 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
     2941 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
     3001 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
     3061 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
     3121 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
     3181 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
     3241 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
     3301 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
     3361 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
     3421 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
     3481 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
     3541 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
     3601 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
     3661 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
     3721 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
     3781 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
     3841 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
     3901 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
     3961 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
     4021 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
     4081 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
     4141 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
     4201 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
     4261 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
     4321 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
     4381 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
     4441 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
     4501 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
     4561 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
     4621 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
     4681 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
     4741 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
     4801 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
     4861 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
     4921 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
     4981 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
     5041 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
     5101 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
     5161 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
     5221 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
     5281 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
     5341 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
     5401 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
     5461 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
     5521 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
     5581 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
     5641 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
     5701 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
     5761 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
     5821 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
     5881 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
     5941 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
     6001 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
     6061 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
     6121 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
     6181 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
     6241 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
     6301 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
     6361 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
     6421 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
     6481 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
     6541 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
     6601 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
     6661 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
     6721 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
     6781 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
     6841 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
     6901 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
     6961 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
     7021 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
     7081 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
     7141 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
     7201 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
     7261 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
     7321 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
     7381 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
     7441 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
     7501 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
     7561 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
     7621 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
     7681 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
     7741 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
     7801 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
     7861 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
     7921 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
     7981 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
     8041 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
     8101 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
     8161 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
     8221 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
     8281 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
     8341 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
     8401 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
     8461 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
     8521 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
     8581 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
     8641 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
     8701 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
     8761 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
     8821 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
     8881 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
     8941 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
     9001 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
     9061 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
     9121 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
     9181 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
     9241 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
     9301 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
     9361 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
     9421 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
     9481 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
     9541 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
     9601 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
     9661 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
     9721 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
     9781 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
     9841 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
     9901 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
     9961 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    10021 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    10081 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    10141 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    10201 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    10261 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    10321 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    10381 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    10441 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    10501 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    10561 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    10621 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    10681 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    10741 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    10801 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    10861 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    10921 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    10981 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    11041 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    11101 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    11161 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    11221 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    11281 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    11341 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    11401 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    11461 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    11521 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    11581 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    11641 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    11701 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    11761 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    11821 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    11881 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    11941 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    12001 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    12061 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    12121 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    12181 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    12241 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    12301 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    12361 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    12421 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    12481 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    12541 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    12601 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    12661 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    12721 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    12781 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    12841 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    12901 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    12961 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    13021 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    13081 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    13141 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    13201 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    13261 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    13321 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    13381 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    13441 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    13501 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    13561 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    13621 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    13681 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    13741 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    13801 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    13861 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    13921 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    13981 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    14041 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    14101 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    14161 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    14221 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    14281 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    14341 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    14401 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    14461 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    14521 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    14581 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    14641 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    14701 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    14761 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    14821 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    14881 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    14941 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    15001 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    15061 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    15121 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    15181 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    15241 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    15301 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    15361 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    15421 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    15481 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    15541 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    15601 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    15661 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    15721 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    15781 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    15841 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    15901 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    15961 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    16021 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    16081 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    16141 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    16201 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    16261 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    16321 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    16381 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    16441 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    16501 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    16561 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    16621 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    16681 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    16741 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    16801 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    16861 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    16921 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    16981 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    17041 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    17101 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    17161 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    17221 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    17281 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    17341 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    17401 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    17461 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    17521 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    17581 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    17641 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    17701 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    17761 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    17821 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    17881 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    17941 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    18001 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    18061 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    18121 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    18181 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    18241 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    18301 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    18361 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    18421 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    18481 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    18541 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    18601 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    18661 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    18721 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    18781 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    18841 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    18901 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    18961 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    19021 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    19081 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    19141 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    19201 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    19261 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    19321 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    19381 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    19441 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    19501 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    19561 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    19621 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    19681 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    19741 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    19801 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    19861 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    19921 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    19981 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    20041 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    20101 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    20161 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    20221 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    20281 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    20341 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    20401 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    20461 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    20521 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    20581 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    20641 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    20701 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    20761 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    20821 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    20881 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    20941 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    21001 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    21061 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    21121 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    21181 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    21241 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    21301 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    21361 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    21421 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    21481 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    21541 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    21601 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    21661 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    21721 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    21781 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    21841 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    21901 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    21961 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    22021 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    22081 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    22141 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    22201 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    22261 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    22321 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    22381 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    22441 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    22501 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    22561 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    22621 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    22681 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    22741 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    22801 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    22861 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    22921 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    22981 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    23041 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    23101 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    23161 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    23221 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    23281 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    23341 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    23401 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    23461 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    23521 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    23581 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    23641 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    23701 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    23761 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    23821 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    23881 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    23941 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    24001 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    24061 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    24121 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    24181 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    24241 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    24301 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    24361 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    24421 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    24481 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    24541 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    24601 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    24661 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    24721 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    24781 aagcagttta ttcatcaaaa aaataactat tgtggtagga taaatctttg agggggaatg
    24841 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    24901 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    24961 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    25021 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    25081 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    25141 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    25201 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    25261 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    25321 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    25381 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    25441 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    25501 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    25561 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    25621 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    25681 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    25741 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    25801 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    25861 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    25921 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    25981 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    26041 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    26101 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    26161 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    26221 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    26281 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    26341 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    26401 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    26461 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    26521 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    26581 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    26641 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    26701 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    26761 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    26821 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    26881 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    26941 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    27001 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    27061 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    27121 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    27181 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    27241 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    27301 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    27361 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    27421 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    27481 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    27541 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    27601 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    27661 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    27721 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    27781 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    27841 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    27901 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    27961 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    28021 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    28081 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    28141 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    28201 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    28261 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    28321 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    28381 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    28441 gtaaa
//
LOCUS       DADQCX010000032        28133 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.032, whole genome shotgun sequence.
ACCESSION   DADQCX010000032 DADQCX010000000
VERSION     DADQCX010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.032"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            166..1206
                     /locus_tag="J8R83_001274"
     CDS             166..1206
                     /locus_tag="J8R83_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAZ9574410.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SSPSTITKDWLE"
     gene            2047..2379
                     /locus_tag="J8R83_001275"
     CDS             2047..2379
                     /locus_tag="J8R83_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAZ9574411.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            2998..3339
                     /locus_tag="J8R83_001276"
     CDS             2998..3339
                     /locus_tag="J8R83_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAZ9574412.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     NEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            3358..3648
                     /locus_tag="J8R83_001277"
     CDS             3358..3648
                     /locus_tag="J8R83_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574413.1"
                     /translation="MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCL
                     HELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIIDEQKSCVLSIDSTLV"
     gene            3840..4073
                     /locus_tag="J8R83_001278"
     CDS             3840..4073
                     /locus_tag="J8R83_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574414.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWREHNGIKDLKPARPVIRRKKLKK"
     gene            4479..5150
                     /locus_tag="J8R83_001279"
     CDS             4479..5150
                     /locus_tag="J8R83_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAZ9574415.1"
                     /translation="MKKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPID
                     QINEHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQAFAQIQIPALGLTLPIFK
                     GANQYTLSLGAATYFYEDAEMRKGNYVLAGHNMEIPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            5203..7182
                     /locus_tag="J8R83_001280"
     CDS             5203..7182
                     /locus_tag="J8R83_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAZ9574416.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDVDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQAL
                     PREDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNNS
                     KGNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELT
                     KFGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVE
                     VPSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVID
                     KTVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDT
                     AGQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASL
                     HGQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLK
                     VDSGLFGTGIKATPLESAEFAAKNAEGKYYGGLVDTDKNGVKEAVWVDDVANAAILKS
                     DKEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKAS
                     VPMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            7197..7949
                     /locus_tag="J8R83_001281"
     CDS             7197..7949
                     /locus_tag="J8R83_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9574417.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWTWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            7965..8726
                     /locus_tag="J8R83_001282"
     CDS             7965..8726
                     /locus_tag="J8R83_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574418.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLFSDQLKLVSNGKTKTIDQQT
                     GVFEFSIEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            8739..8999
                     /locus_tag="J8R83_001283"
     CDS             8739..8999
                     /locus_tag="J8R83_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574419.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            8996..11086
                     /locus_tag="J8R83_001284"
     CDS             8996..11086
                     /locus_tag="J8R83_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAZ9574420.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKTTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            11113..11577
                     /locus_tag="J8R83_001285"
     CDS             11113..11577
                     /locus_tag="J8R83_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574421.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            11574..11816
                     /locus_tag="J8R83_001286"
     CDS             11574..11816
                     /locus_tag="J8R83_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574422.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            11834..12136
                     /locus_tag="J8R83_001287"
     CDS             11834..12136
                     /locus_tag="J8R83_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574423.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            12206..14269
                     /locus_tag="J8R83_001288"
     CDS             12206..14269
                     /locus_tag="J8R83_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574424.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHEGRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYSTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEKENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHEIAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIRERKEEFYQGLRTDKLKISKELNEQLNKLYQIT
                     SEALMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEE
                     AQEQARKEYEQQLEELLNRTNQATTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            14269..16878
                     /locus_tag="J8R83_001289"
     CDS             14269..16878
                     /locus_tag="J8R83_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAZ9574425.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAILMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPENDYRQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHQGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     TNSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLHQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            16875..19271
                     /locus_tag="J8R83_001290"
     CDS             16875..19271
                     /locus_tag="J8R83_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574426.1"
                     /translation="MIIGGIFSGIANWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLETDPNKVESLPTDKRNALTAKNFKTANINSVII
                     PKEAAKMADEDKSGLSDIQKDRLRALQYRLELDDNGKEIPVEISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLNDIRKNGF
                     GNRKDVIPDNGEEQPDDKATIVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQY
                     RYKSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSMKIGLPKTQNLP
                     MKDSRLNQFKENDQSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNVSIQN
                     VVTREAAPEPIQKVHTGYKPANVAFTAPTKINVTRETKNRNNELKEQLLRDIKQDIKP
                     "
     gene            19323..19655
                     /locus_tag="J8R83_001291"
     CDS             19323..19655
                     /locus_tag="J8R83_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574427.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19656..20249
                     /locus_tag="J8R83_001292"
     CDS             19656..20249
                     /locus_tag="J8R83_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574428.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVQTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            20412..22106
                     /locus_tag="J8R83_001293"
     CDS             20412..22106
                     /locus_tag="J8R83_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAZ9574429.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASRLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            22794..24671
                     /gene="ltrA"
                     /locus_tag="J8R83_001294"
     CDS             22794..24671
                     /gene="ltrA"
                     /locus_tag="J8R83_001294"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAZ9574430.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            24802..25179
                     /locus_tag="J8R83_001295"
                     /pseudo
     CDS             24802..25179
                     /locus_tag="J8R83_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            25179..26384
                     /locus_tag="J8R83_001296"
     CDS             25179..26384
                     /locus_tag="J8R83_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAZ9574431.1"
                     /translation="MENQDESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNDNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            26400..27044
                     /locus_tag="J8R83_001297"
     CDS             26400..27044
                     /locus_tag="J8R83_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574432.1"
                     /translation="MENKTLKIVLTAALSISLIGNIALFWQLKEEQATNTYKIEEVAK
                     NASEKLKKNFSEAQAKIDKLNQTINEKNQEIDQLKQQDGIKAKEEVTDAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAETS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            27055..27861
                     /locus_tag="J8R83_001298"
     CDS             27055..27861
                     /locus_tag="J8R83_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574433.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFTILGFLILASPIYTHKKVNI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQGLLKELANLDYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIVPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDDNYEQHAINYKVKGYKKEQKAAQKQIESLQATIDLNEELVNKLKDQLP
                     YQVADDQENTENKINDYQQEIETSKTQMKDQEEIIQKIQEKIDRMTKENI"
     gene            27884..28114
                     /locus_tag="J8R83_001299"
     CDS             27884..28114
                     /locus_tag="J8R83_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574434.1"
                     /translation="MKGANLVGKDIFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKIRSFEALYLAAKKYFTAERK"
BASE COUNT        10421 a         4318 c         5773 g         7621 t
ORIGIN      
        1 taatgacttt aaaggtagta cataattcat tttatttctt attttaggta gtatttaatt
       61 aaaaaacagt tttaatgcgt ttgcattttt tatttatctt tgctattttc gaaaagagta
      121 ggtaatttta cataaataaa acaacgtgaa agtagaggat ctacaatgac tgattttaat
      181 ttttttaagg cggatagagt ttacaacgaa ttattttatc aatttccaaa agtctttatt
      241 gtttctgacg aatacaaaaa aatgaaagat tcaactaaga ttgcctatat gcttttaaaa
      301 gcaagattag agatcgcaat cagcaaacgg caaatcgatg aagaaggtaa tgtttatttt
      361 acttatacga caaatgaact atgtagcgta ttaaactgcc aaaaacaaaa agcgatagca
      421 atcaaaaaag agttggaatc ctttggttta ttattacaaa agcagatggg atttaacaaa
      481 cagttaggga aaaataatcc taatagacta tatctagcag aattaaaagt ctcagaaaat
      541 gatatctact tactcgaaaa atttgataga gagaataggg aaaatgttga taaatcagag
      601 ggtatgaaaa tcatacccac cctcgacgaa aaatcagacg ctgaatccct tggggctcaa
      661 gagggtatga aaatcatacc gtgccaaaac gttgataaat cagagggtat gaaaatcata
      721 ccagaactta ataataatat attagacact aatagacaca atatagacac tgaaaaagac
      781 cgcctacaag atcaattgtt gttagacaat tttgagacaa ttatgacaaa cgacagcatt
      841 gctacgtttg tccctgaacg agtattaaat ttgataaaaa cattttcttc aagttacagt
      901 gaagctcaaa aaaccgtcca gactattcat aatgcaaaga aaaaagctga aatagaaagt
      961 ggtatttcga tagtttttga agaactcgat agttattatg tcaatgcaga acaagaatta
     1021 tacacgacac tgttaaaagc ctatcaaaaa ttaaaaaccg aaaaagtcga aaatatccag
     1081 aacctgattt ttgtctatgt aaaaaattgg tttatcgaaa aaccaatagc tgctaaagta
     1141 tcaagtgaaa aacgtttgaa ttctgaaagc tccccaagca ctattacgaa agactggtta
     1201 gagtgaaact ttactgacaa agtgattgtt gcttcatgga gtaacattaa agttaaaaat
     1261 tttttattat tctaattata ttacgaatat tacaaaataa tagctatttt aatagaattt
     1321 ataagttaaa atattatgat aaaaatcaca aacgtagcct tttacgtcat aagtgttaaa
     1381 agaaataatt aatttcaaat ataaaaaagg gaacgtatgt ttgcatactc cttttttttg
     1441 agttataata atacgcgaag agagataatt tcattattta aacaaactaa aaatcttgat
     1501 attacttctt ttcaggcaat acgaatatta ttcgcttaca tttttttgta taaatttagt
     1561 tgttttaaat ttaattgtct gctatgcctg tgatgaattg attttcgttc tgcacttttg
     1621 gacgataaat ttggacaatt gaaaatacaa aaaaaaagaa aggcggtatg aactcggaag
     1681 gctggtaacc ttcgtcagcg ttcatacacg gcattaagat ttggccctta atgcgttaac
     1741 ctttcagtgt tacggtatta cccgcaatgg atttagtata acagatattc aaaagtgata
     1801 ccactttttt tggctgtgtt aaggttaaaa atacgtgata ttacgatgaa tctatgccta
     1861 agcataatgt tataaaaatg tccgtgtggc tctttgccgt atgacgaacg ctgaaattag
     1921 agggaacgca tgtttggatg cgttccctct tttttgtttg tcatgaacga aaatcaattc
     1981 tctatttttg aaaaataaca agaaaaactt gttaaaaata tttaaagaaa ttgggtggtt
     2041 tattttatgt catatacagg aattttgagt ctcaaagata tttgtcacta cggtaaacgg
     2101 tgtaccgcta cagagaaaat cacgaagaaa ctatcaactg gccaaagtaa aaccgttgtg
     2161 cagtgtaaga aatatataat ccagaaagac aaagtctcag aggaaatgat ttattacatt
     2221 gggaaacaaa agcaaataat tttaaaagat cctatcccct taaaagagct atatccaaca
     2281 atcaaacatg tttatgacca aaacggtgta ctgattggtc gaagaaaaaa tggagtcttg
     2341 cgttgtaccg caaaagggat ggggcgttta atcagctgaa ttgatcattc tcataacttg
     2401 tattttatcg tttttcgctt gcttgaaaat attgtcgaga cttctaaaag aacttagaat
     2461 cattagaaaa ataaggagta gacttgatct atcaacaatt tccttcgggg agtgacgggg
     2521 tagattttta cgattggtaa cgtaaaaaat tggtcaatcg agtaaatgcg cttgtttgga
     2581 tagtggtgaa atgaatttgt gtaaataata tacacagagt aaacaagagg gaatttagag
     2641 gttagacaag ttagaatagc gcctagatta atcatgagca gctactaagg gatctaggct
     2701 ttgacgcaaa ctcatggaat aaggagtagg tcttctcgta atggggagga cgcacaagaa
     2761 attgtgtcgt gtgctgcagt acatgtagat acttgcgagg acgttggtca ttgggtcaat
     2821 cgagcattta ccgctgtcta ctagggtttc tcgtttcgga cgccataaac gagtcgatat
     2881 tttttatgta tttttaagta aacgaaaaac gataaaatat gaacgagtcc tgaataaagt
     2941 gaaaaaattg atataaaaca tagagaaaat gaaatttacg taatggagga atgacaaatg
     3001 aaaaattatg atccgaatat acgattgggc acacatacta ttaaggtttc tttccaacgt
     3061 tgggattaca aaggttttgt gacgtttaga agaggcggaa attgtaaagg attagatgtt
     3121 ttagcattaa acgaggatga tttatacgat caaacattga ctgataatcc aattggattc
     3181 ggcttgctac ctgaagatga tgaaggtaat gaatggttta aaatgacgct tatgaatgat
     3241 aatggagacg aattatctgt tgaagatact tggtcatatt tgagtgatta tattgtcagc
     3301 gttgaaatca ttgaatttgt agcggataaa gaagaataaa aactggagga ataaattatg
     3361 aaatttttcg aagtaaaatc accatactat tatgcgttaa tcgcagcaaa gaatgaagaa
     3421 gaatgtgcag aattgtatga acaagtagta acagatatcg aaaatcgtga agaatttatt
     3481 cgatgtttgc atgagttaaa tcgaaatgaa gcaattcaag aggatgcgaa aaaaattagt
     3541 gaagaaacgt tacaaccaat cggtatggag gaagctacaa aagacatttt tacaattatt
     3601 gatgaacaaa aatcttgtgt attaagcatt gattctacat tggtttaata gatccaagat
     3661 tctataattt ttttcaaagt aaaaagaaat taggtaatga ttctcagacc aattacttag
     3721 gaaaataacc atacaaatta gattttacag ataaaggatt agaaggaatc acggcgatta
     3781 ataaaaaggt agtattacct taggcattga gtaaggaatt tatttaggag gaaaattaga
     3841 tggcgcgacc agttttagat gcgatggata tggatacttt gacaaaagga aggtatgtac
     3901 agctgttagc tcgtggttat tcacctaaag atgtattcaa agccctatct aaaggaacag
     3961 atatggaaaa agaaagatta cgaaaagaat tcgactattg gagagagcat aacggaataa
     4021 aagatttaaa accagcacgt ccagttatta gacgaaaaaa attgaagaag taagaccaaa
     4081 gcgtatggcg tacataggct tttttatttt gataaaaata atgaaaggaa ggaaaactca
     4141 tgaattgtaa agaaatcgaa aatagaaaaa aagtgtcgaa agaaatggaa gaaaagttac
     4201 taaaaacaat gaaacaaaaa caatgaaaca aaaacacctt aaaagattat ctgtcgcgca
     4261 atatatcaat gatatgcagt taacaggaaa agagaaagct tgtttgttag gttcaatgaa
     4321 aaactttgaa cagttgagac gaacttatgt gaaaaaaagt tctaattgtc aactattgtt
     4381 agaagtctca tgacattcat taatagaatt catttttaaa actttttcta tggaaatgag
     4441 aaaaagtttt tttgttttgt ctgaaaggag gcagatggat gaaaaaatgg ttatttggtt
     4501 ttttaggagt cgctttaatc gtcttttgca gtgtgtttgg ctatgttagc taccaaaaac
     4561 atgaaggaga ggtgtttaag caaaatatag aaaaaaagat gcccatagat caaatcaatg
     4621 aacatgcaaa gagttataag gaggatgcaa cgaacgttaa taatgatatg tctttgggac
     4681 aaatgttgtc catacaaaaa gaagcaatcg aaatgggcgt caataaacaa gcctttgcac
     4741 aaattcagat tcctgcgctt ggtttaacat tgccgatttt taaaggtgca aatcaataca
     4801 cattgagtct tggtgcggct acttattttt atgaggatgc cgaaatgcgc aaaggaaact
     4861 atgttctagc aggtcataac atggaaattc caggtgtttt attttctgat attcaaaagt
     4921 tgtcactagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     4981 cgcgtaaatt tatcgtacct gagtacttta aattaatcga tggcgttcct gaagagaact
     5041 ctttcttgtc tttaccaaag aaaggagaga aacccttatt aacgttgttt acttgtgttt
     5101 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caaggtttta
     5161 atcaacgtga gtcgttgaaa tatgaaacga ggagagtaaa aaatggcaat aaatcggtat
     5221 gtaaaaaaag ctggaatgct tgttggaatg ttaggaatca ttgcaggctg ctttcaggga
     5281 tatcgagcat atgcagaaga tgtcacgcaa aaaacgccac cagagaaggt caatatcacg
     5341 gttcataaat taatgtatga tcaaggaacg caattgaatg ttgatgttga cgggatcaaa
     5401 aacgatggtt atacgcacga tcaatatcct acgggtgtaa cgaaatacaa caaggcagat
     5461 tatggtgatg ttgagtttac gttaggaaat attacggatc aagcattacc gagggaagat
     5521 tctgatctaa ccaacgcgaa agtggacgaa atcgttaaag atgtagaaga caagggatct
     5581 aacagtgagt acgtcaagaa tgcaaccaac aaaattactt cagctgtaga tgaaaatggt
     5641 gagattactt ttgctgatca accagcctat gtcaacaatt ccaaagggaa tgtatatgtg
     5701 gtttatgaaa gtaaatccgc tgctggatta gtcacacaaa aagcaaaacc aatggttgtg
     5761 attgcgccaa tgactgataa tacaggttca ggttttttaa aagacattca cttatatcct
     5821 aaaaatattg tttctaagtt gagttttgaa ttaacgaaat ttggtgacga tggcacagct
     5881 caaagcaaac aaacaccttt aaaaggggca aaatttgagt tatacaaggg cgaacctgga
     5941 aaaggaacaa aattaggaga tcttgtatcg gatgatcaag gaaagctgac tgctactgat
     6001 ttgacgttag gaaaatacta ttttgtggaa gttccttcag aagttgtagt gggatcagat
     6061 aaagaaccaa cagccgatca atatttatta ggcgcagacg ctcgcaacga tgcgcacaat
     6121 aaattaacct ttgaaattac gaatgatggc gtgacaagtg acttaaaagc ttcatacgta
     6181 aactataaag caccagtgat cgataaaaca gtaacaaatg gaacaggaca agaacattct
     6241 ttccaaattg gtgacgcagt aaattatcaa ggaacgattc atatcccaac agacattgca
     6301 ggcggagcag acggtatcac agtaaacgga gtgaaaagcg aaacttctcc ttacagtgta
     6361 tttaaatggg gggatacagc aggacaagga ctttcttatg tcgctgctaa agcaaatatc
     6421 aaagtaacaa ataaagatgg atctgtggta ttaaaagaaa atacagatta taaaatccaa
     6481 aattcagaaa atggctttgt gatcgatttt atcgtgaata atggccaagt aagtgatact
     6541 gtagcaagtt tacacggaca agatcttcaa atgacttata acatgtatgt aaatgacagc
     6601 gcagctgttg ccaatccatt aacaaatagc gtggatttcg tttataacaa caatccattt
     6661 aatcaggaag aacaccacga aaaaacgaaa gctgacgttg tgacttatgg tgcaaaattc
     6721 ttaaaagtcg atagcggact atttggaaca ggaatcaaag caacaccgct tgaaagcgca
     6781 gaatttgctg ctaaaaacgc agaaggaaaa tattatggtg gattagttga tacggataaa
     6841 aacggtgtca aagaagcagt atgggtagac gatgtagcaa atgcagcgat cctaaaatca
     6901 gataaagaag gtcactttga aatcactggt ttaactgaag gtgaatattc actggaagaa
     6961 acaaaagcgc ctgaaaacta tcaaaaatta acgaaagaga tctctttcaa agtagacaaa
     7021 gattcataca aagaagaaaa ccgaattacg atcaaaaaca atcaaaaagc ttccgtacca
     7081 atgaccggta gcaacggttt tcaaacgtat gtattaatct cttgcttgtt gctaggagca
     7141 ggggcacttt ctgcagttgt ttactttaag aagaaagcct agaaggatca aaaccaatga
     7201 ttatcaggaa gcctaagaaa aagcgaatca tgggtaaatg gatcattgct ttctggttac
     7261 tttcagctgt aggtgtctta cttttgatgc ctgctgaagc gagcgtggcg aaataccaac
     7321 aaaatcagca gattgccgca atcgatcgaa caggaacggc agcagaaacg gattcttctt
     7381 tggatgttgc taagattgag ttaggcgatc ctgttggtat tcttacaatt ccaagtattt
     7441 ctttaaaact accaatttat gacggaacgt ccgacaaaat tttagaaaat ggtgtaggta
     7501 ttacggaagg aactggtgat attacaggag gaaacggtaa aaatccttta atcgcaggtc
     7561 atagtggact ttataaagat aatctttttg atgatttacc ttcagtaaaa aagggagaaa
     7621 agttttatat caaagttgat ggtgagcagc acgcttatca aatcgatcgg attgaggaag
     7681 tgcaaaaaga cgaactacaa agaaactttg tcacttactt agaaccaaat cccaatgaag
     7741 atcgagtaac gctaatgaca tgtacgccta aggggatcaa cacacaccgt tttctagtgt
     7801 atgggaagcg agtaaccttt acaaaatcag aattaaaaga tgaagaaaat aagaaacaaa
     7861 aattatcttg gacatggctt ttaggaagta ctgtttttct ttcagtcatg atcattggtt
     7921 cgctatttgt ttataaaaag aaaaaataaa ggagggtaac caacatgaga aatagaaaat
     7981 ggctatttgt ttgtgcagcc gctctttttt ctttcactgc ctacacacag ttgacgtttg
     8041 cagacagaca agaaagcacg gatagcacag aacaaacaat ccaaacgtca gatagcagca
     8101 cgattcaaag cagcgatgaa accgtcgatt cgtcaacagt tgattcttca gaagaaccga
     8161 aaattgctga agacgatcaa atagtcaaac agaccattca cgttcaaaaa attatttctt
     8221 ccgaacaatt agacaaccag gggcaaaaac ttgaaaaaca agaaggagta aatggcgcga
     8281 agttttctgt ttatgatgta tcggacattt tacaaaagat ggatgttaag gatctcacta
     8341 ctgaccaaat tgaatcccaa ttaaaagatc gagtgaaaaa actattcagt gatcaattga
     8401 agctagtttc taatggaaaa acaaagacaa ttgatcaaca aacaggtgtc tttgaattct
     8461 cgatagaagt acaggcaaat cagaaacaag cttattatat tgtcaatgaa tcaagtcctg
     8521 aaaacatttc taatagcgag gatattttgc tattaacacc tgtttctgat aaaaacggtg
     8581 aattcttaaa ggatgtgtgg atctatccta aatcagaagc ttcgcaacct aaagaagaag
     8641 taaaaaaaat cgtttctact ggcgtaaaga aaaacttctt tgagaattgt tgggattttg
     8701 ttactcactt gttttctaga gattaaggaa gaaataaaat gaaactgatc aaattattat
     8761 tattcaattt ttcttgttta accgcagtct ttttgtactg cggtttatta ttttctaaac
     8821 tatctatttt gccaagctac caactatacc taatgaggat tttaaacata ccagctgctt
     8881 ccatgccgct agatattatg gaaaagctca ttaggaatcc attatttact acgatcaatt
     8941 tgatcgttat tgtcggaatt tcactagtca tttataaaaa agaggggatg aagggatgaa
     9001 ttttaaacac tcgtggacaa gacggttaaa atatgttttt cccataatga tgatgttagg
     9061 tacattgttt gggttaaaaa cagccaatgt ctttgctgaa aaagttattg tcgatccgtc
     9121 aaatccaatc cagaacgtaa agaataattt tattattcca aaagatgttc ctaatgcaaa
     9181 aacaaatatt actgtaaacg gagcgtcaaa agtttacaaa tatcatgttg atgccaacaa
     9241 aggtggtttt acagacgact acgtaggatt agtggaggga aacaaaaata tacgctatcc
     9301 ttctttccaa aaagaatacg gtgaaacaaa ccttgtttta gaaggcgtaa caaccaacac
     9361 caaagtcaat attgactatg gaaaaatcgg tacgtataac gggaaaaaag tcaatatcaa
     9421 gctagttcta tctaatattc acttatactc ggatacgttg ccgtggaatc tactagataa
     9481 caactataca aaaactcatt ttcgagacga tggctataaa aatacgaatg gtgcaatgag
     9541 taaatctaaa aaaagaacag tactttggat ctcagacaat cttttctcag gaattgttta
     9601 ccattcaaca caaatgaatg tgcagctagt agccacatat gaggacggta gccccgttca
     9661 attttcagga gatacattta tcagttttaa ctctttgaac cctgcaggag gaaaaaccac
     9721 ggatcttaaa ggagaatatg cccactatga caaaatgaat acgacagatt ggtatgtcag
     9781 aaaagatacg gttctttcag aatttaaatc tttctacaac aatctgaacg tggtaggtgg
     9841 ccacccagga ggaagctcta agctgacaca agcggataat gatttcaata atttgcatga
     9901 taaattagga gatccgaagt ttggtcaagg tactgtgtcc tttaaaatat ctgaagcaaa
     9961 tccgacgttt gtgattggtt cttctaatgt tcaaacctgg tttactttat cttctgcgac
    10021 aatctttagt gttgttcctg atcaacctga aaaaacaggg gttgataaaa atggaaataa
    10081 cgtgaacgat aaaatgttgc aagtaggaga cacgattcaa tatcgaatca aacagaaggt
    10141 gaatcgatta ggagtggatt tactagcggt ttacgatcga tttgagttaa tcgataattt
    10201 accaaaagaa gtaaattacg tcgatgcaca cgttgaaagt ggtacaaata aaaaattcga
    10261 tgtatctggt gaagtgacct atgacaaaac aaaacaccag gtaaaatatg cagcgaaagc
    10321 tgatacatta aaaaatcgaa tgaagtataa cggcgaaact tacgaattag tgatcaatgt
    10381 aaaagtcaat gaattggcca atcaaaatag tgtagccaaa aatcagggaa cgtcgatcat
    10441 taataaagta gaaaaggata caaatatcat taccgtttat ttccctaaaa ttccagtgaa
    10501 agaagtacaa caaaatggaa aagatgtaaa cggacgaaat gacggtaaga agggtacgcc
    10561 gacagctcct ttaaacgcag gatctgaagt acaatatcta gtcacacaaa aatggcacac
    10621 aaaaggcgta gacgctgcgt cagatcacta caaacaattt agtattcaag atccaattga
    10681 agctcgtttg acatataaag aaggttctgc gcaagtaata gataagagta aaggaaaaga
    10741 tattacttct gaaggcacac taacctatga tagcaattca agaacgctga agtgggaagc
    10801 ttccgctgac ttcttaagta acaatctttt agatggacga gaaattcagc tgatatttac
    10861 agctaaaact ccattacaat cagaaaaaaa tattgataac caagccgtag tagcagtaga
    10921 taatgtttct aataaaacaa atgttgtgac aattggggtt gatcctaact tgccacaggt
    10981 cattgttcct aaaacaggtt ctacacattt agtaacgatt tcagcggtca gcttactatt
    11041 acttgtgtta gcaactttta gttatgcggt tctgagatac atttaaaata aaaaaacgaa
    11101 agaatgaata aaatgaaaaa gttaataata gtagttactt ccttgattgc catgattgtt
    11161 attttagtcg gatgtagtaa tgaaaaaaat aaacaaacta atcaagataa tggcgtattg
    11221 aaatcaggaa ctatgtggaa agaagaagta ggtggtcttg tttataattt gaaaattata
    11281 gacgagacta cctgggaata ctctgagagt gtatggcatc cagatcctgt acaaataaca
    11341 gtcaagaggc aaaaagacta taaaggttta gaaagataca aaatagtaga ttcagctggt
    11401 gttagggaat ttataaacaa atctgattct ttatttattg ttgttcccta tgagaagaat
    11461 ggcgtaaaaa aaataatttt tcttggatct agcaaggatg aaaagcgaac gaaagagaaa
    11521 ttgattcacg atggatcaca atccaataaa tataagttac aaaagactag cgagtgattg
    11581 ctagtctttt tatttgtcct gaaggaggaa tcacagtggc aaaagctaaa acgccatttg
    11641 aaaaagccgc gtctaaaatc ttagaacgcc gcggtgtatc tgaaacacag tggaaacaag
    11701 aagtccttga aaaagcacaa tttgacctat tacggggaaa agacaaggac ttagaaggat
    11761 atatctatca acgtgaacgt gaaaagcttg ttttcgacga aattattaaa cactaaaagg
    11821 agcgaacaat tttatgtttg aatcaattac aatgaatttt ttaacacaac cgaaagtagt
    11881 agctgcggtt gatattttta gagcattaca aactgccgca actagtttaa aaaacaatct
    11941 gatgattttt gctgctgctg cggccgttgc ttccattgtt attgggggtc ttttcttcct
    12001 atttggacga agaggagctg aaaatgggaa gatgcacgta ggctatgtat tgatgggggt
    12061 aggagttatt ttagcagcag cttctattgt ggtttcgtta tttggattgt ttggacaaac
    12121 acctcaagga ttataagaaa gtaaaaaagt aggagtaaga agtagtcgat actttttact
    12181 ccttttttat gaaaggagaa tactcatgta ctttacgatt gcaggcaata ccaaaacaga
    12241 taaagagtta ataaaaaaag caacgaagga agtaggaaag cgtacttctt ttttaccgaa
    12301 aacaattaaa tattctgtca ttgaaacgga agaacagcta catgtgttag ggaaagtact
    12361 ggaacacgaa ggtcgatctt ctgttaagtt gactctcacg ttacatgaca cagaaggaaa
    12421 aatagagaaa gctggtacag aatacgtttt tggcccactg gattatcaaa tttcagaagg
    12481 tttctattct acattgatgg atttaatccg ccttgatgtg tttaaagaaa cggatgaaac
    12541 tatgagtgtg gaagagtctt atcgaaacga aaaactttta caagttttag aagaagagtt
    12601 agagagcgac caaagaaaag tgaatcaagg gagtgaagtc gaagtaaatg aagaagtacc
    12661 atgggaacga ccaatatttc caaagaagga gtcaaaagaa aaagagacag tctatgttga
    12721 cgaacaagct gatattccga ctcagaaatc gatatttgag aaagagaacg atgtgatggg
    12781 tcagttggag gtagatccct ttgaagaaac aatggaggat gaagagacgg ccgaagtaga
    12841 agttgatcca gttgaagcta atgaagagtc aacatggact gaaggggatt ctcaggaata
    12901 tattgaacca cttatcagtg aagaagtaga aaaaaacgaa atagagatac aaaaggcaac
    12961 tgtatttgat tatattttgg atcaatatcc gccagagcat gaatggatga aagaaaaaaa
    13021 caaattattt ttaaatgagc tttattcgaa atatcaatta ccccaaacct atcaagcatt
    13081 tttagagagt aaagaagaat taatctcaca gggtaaaggc acacttttag aacagttaga
    13141 gtctgtccaa tcaacaaatt ggcatgagat tgcacaagaa gatttattag ccacctttga
    13201 agaacgtcaa caagaaacag atcaagaaat taatgagtat gcgacggaac agtcgtctaa
    13261 ttgggagaaa gcaaaagagg aactaaataa agaagaacag cgagtgattg aagaagaagt
    13321 acaaaaaatt aaagagcgat acgaaaagaa acgcgacaat gcgtattcct tgtgtgtaga
    13381 aaagatcaat aattttactc agacgaatca agaagcgtta tcgaaagaaa aagaaaactt
    13441 gttaaaagaa cgtataagag aacgaaaaga agaattttat caaggtttgc gtacagataa
    13501 gctaaagatt agcaaagaat taaatgagca actgaataag ctctatcaaa taacaagtga
    13561 agctcttatg gaaaaacacg agcagatcca gcaagaatta caagtacaaa ttccaaaatg
    13621 gaaaaaagag tatgaaattc aacaacaaga attgaaagaa caagaagaaa aacaacggca
    13681 aaaagaaaaa gagcgcgaac aattagaact aaaaaaacgt gaacaggatc ttgcggaaca
    13741 acaaatggca atagaaaaac aacggttaaa ccaagaaaag gaaaaagaag cagctgctcg
    13801 taaggaacgt caagaacaaa tggatacatt acgacaagct cagttaaatt atctagcaca
    13861 acctcaacca acgccttcag tagctgctgt tcaaacccca atgaacaacc aaacaaatct
    13921 aactccttca ccacagcgtt cctttaacgg atggatggtg ggatgtattg caagtttaag
    13981 cttgcttcta ggtggaggga cagtatttgc ttttaatcat atcaatcaat cttcacaggc
    14041 tgattctgta gccacaacgg cgtcaatcaa ggaagaagcc caagaacaag caagaaaaga
    14101 gtatgaacaa caattggaag aattattgaa tcgtaccaat caggcaacaa cagagtcaag
    14161 tatggaaaat agcaaagaga gtgatcctag taaggctaaa gaaggatcaa gcgattcaac
    14221 tgtacaatca aacacttccg aaagttcaga atcaaatgag gtgaaataat gcgtgttaga
    14281 gaaacaacga gacgaaaaga caaacgattc aatttagaaa agaataggta tctttctcat
    14341 ttctatcgct atactccttc aggagaagag ctaccagaaa aacatgacaa acgtatttct
    14401 caaaagattt tttatagtgg cttagcttat cttcctttaa actatgttgt tacaagaata
    14461 ccagaagcat ttcatcgatt tgagattatt ccaggaagtt tacaaggagt gaatattttt
    14521 cagttacaag aaatgccgca gttattccat tttgattcaa ctggtttttg gaatcctttg
    14581 accccaacaa caagtttagg cacacgttta gttgtttcta cgatttgtgt tgttccagct
    14641 atacttatgg gattgaaaat ggacatgtgg tttcgtcctc tagcagatgg gcaaaaagga
    14701 gataaccgat taaaaacgtt aaaggaaatc caacaaattt atccgcaaat accagaatca
    14761 aagggaggtt ttcctggtta tggcggaata ccaattactc attataaaaa gtactggtat
    14821 attcagacgg atacagtaaa tacttgtatt gttggtactt cccgttcagg gaaaggacag
    14881 atagaagttt tagcaaccat tgacaatttg tctcgtgcag aaagacaaag ttcaatggtt
    14941 gttaatgatc caaaaacaga attatatgtt gctagtaaag atgaactaga agctagaggg
    15001 tatgatgtgt atgcatttaa tatcaccgat ccactgcaat caatgagtga taatccattg
    15061 gcactcatcg tgaaatactg gaagcgagga gacatagata ctgcaacgca gttaaccaat
    15121 acttttacga atacgattta ttatgatgcc aatgcttcag acaacaaata ctttaacgaa
    15181 aatgcgcaga aagctgtaaa tgcgcttatt tttgcgttgt tagaacaagc cgatcaaaca
    15241 ggggattact ccaaattaac acccaataat cttgttgagc ttctttctga aattggcggt
    15301 tttaattatc aagatcctga gaatgattac agacaactca atgccttaga tgaattcatg
    15361 aatcagttac cacctggaaa catagcaaaa aaacaatatg gggcaacaaa aattggttct
    15421 gataaagcaa aagggaatat tttatcgacg gcaatcacag gattgaatcc atttacccta
    15481 acgaaaattg cgaaaatgac ttctcaatca accattgatt ataagtccat tggttttccg
    15541 aagtatttgg atctcaaact acacgagagt ctgttaaatc agcgaattgt tgtagagttt
    15601 tatcatcaag ggaaaaaatt tcatgaggaa cgtgtcaaag taggttatag aggtttttgt
    15661 gaaatcaact ttgattgtca tttagagcag ggagatcatg tttgcttaaa atacgatcat
    15721 caaggaaaag aatatgttgc ttggtatgag ttttctcaaa gagtattgaa agacgaagag
    15781 ggaaatatcg tttatcgaaa aaaacgagga gaaacccatt taccagaatt agaaaaagaa
    15841 gctgttctaa cattagatga ggataaaagt aacttattag tagagtctat tcggatgcac
    15901 tataccgata aaccaatggc tatttttatg ctcacacctg attatgatcc atctaaccat
    15961 atcattgtta gtatttttct tagtcagttg tataaagaat tatctacgca atgtgttaag
    16021 actaaaggag ataaatgtca ccgtaggatt cattttattt tagatgaatt tgggaatatg
    16081 ccaccaatgg ataatatgga aggaatcatg acagtcacag ctggtagaaa catgttgtgg
    16141 gatctgttta ttcaatccta tcagcaactt tatgcgaagt atggggaaca aaacgcagcg
    16201 attatcaaag aaaattgtca gacacatatt tatattatgt cgacagacga taataccatc
    16261 gaagaatttt ccaaaaaagt ggggaataag acggttgaac aagagaacag taccaccaat
    16321 tcattaggta tgaatactca tatcaatcgc aatgttgatt cagatcgtat cttaactcct
    16381 gaaagaattt ctactttttt agaaggtgaa acgattgtac tcgctccttt aaaacgacaa
    16441 gatttgaaag gtcataaaat acggccgtat cctattttta atcatgggga aacgaatctt
    16501 ccttatgctt atcaatatat tgaagatttc aatccatcgt gggatatcaa tgatatagac
    16561 atacattgta cacatgcgga cttggatctt aaggctttac aaattgatta cgattatttt
    16621 ctacctgata tctatgcacg tcgactttat cacaatatgc acgatcaaat agaagaggaa
    16681 gctaaagaaa acatttttat taaaatcgtt caatctttag acaactcaac ggcacaaaag
    16741 ttacttattc aattttatga agagaagcaa atagatcgtt tgcaagaata ccttgaaaaa
    16801 ttgcatcaaa atgaagaaat tacagaggtt ataaggaaac gacttttgct agaagctgaa
    16861 aaggcggtga aagaatgatc attggaggaa tattttccgg cattgccaac tggtggtcag
    16921 gcttatttgg ggatggggat gcagatccca aaaccgtaac gaaagtctta caagattatg
    16981 gtaattatct gcagtatcaa gatgtattca gttggatttg taatactttt ttatggggtt
    17041 tgattaaagg gttatataat ctcaatactt tactagaaaa aacaatttat caaagctttg
    17101 atttaaaaga cttattgaac gctgctggtg ttaatgaact gtttcaaagt ttgattagta
    17161 aggtattggc tcttttttgt gtcgtcacat taatttattt aggcttaaaa ttttttatga
    17221 gtaaacatcc accaaaaatc aaaaatatct tggttaatct atttatggcc atgattttga
    17281 tttttggtgg tagttcttta atcgatgaag ggctaaatat tagtaaaaac ttttacggag
    17341 acgtgactgc agcaaataaa gcagataaaa ctggatcacc tgcttttcaa attattcaaa
    17401 ataatgtgat cgatgtgagt acgctactag aaactgatcc gaataaagta gaatccctac
    17461 caacagataa aagaaatgct ctcacggcga aaaactttaa gacagcaaat attaattcag
    17521 tgattattcc taaggaagcc gctaagatgg cggatgaaga taagagcggt ctatcagata
    17581 tacaaaagga tcggctaaga gcgttacaat accgactgga actggatgat aatggaaaag
    17641 aaatccctgt agagattagt gatgaggggt tagcaaaata tgtgtatact tcaggctatc
    17701 gccgatacat tagtagtcca gggattattt tagctggtga atcttctttg tcggttgcct
    17761 atttatttat cttgtttacg attgtaactt gcattattga gctggtattt aaaaaattct
    17821 atttagtaat tgccgcgtca acggactttg agacaggaca acggatgaaa agtgctatag
    17881 aagatatttc tcaatccttc ttgttattgg cgtttacgat tttagaatta cgaatctata
    17941 cattaatgct gtcaggtatc ggtgatttgc acgcagcagg caagatcaac ggatttttgt
    18001 atgttgtcgc tttaattgta ctaaccattg cgctattcaa aggctctcaa tctgttacga
    18061 agattttcgg tgttgataca agtctgaaaa acggcagcaa ttctcttctt agcatgtttg
    18121 ccttaggaaa tattgcgaaa aatgtgggta gtggggctaa aaaccttgca agtgctggta
    18181 agagtggttt aagcaattta aatgatattc gtaaaaatgg atttggcaat cgaaaagatg
    18241 ttattcctga taacggggaa gaacaaccag acgataaagc tacaattgta cctaatagta
    18301 agaaaacagt ttccgaaatg ttcgggaaag cgaaaaatgg tgtttctaaa gccgcagaag
    18361 gtcttggtta cgtcaatgaa cgtgggttaa aaggaacagc tgaagatctt acagaaaaag
    18421 ccaaagacac cttagaagag aaattagacg gcacgagagc taaagaattg gctgaagctg
    18481 tgaagaatcc atccgaagca ctagaaaaac aaaaagaaaa agcttcagaa gtcaaagaag
    18541 gactaaaaga tgcgtatggt gaaggacaag tcaatgcagc agtgaaggca aatacaacaa
    18601 gtgaaaaaga aaatcaagaa ggtgcagcga ttccttcagc caaagatcac caagatgagt
    18661 tacattctaa cgaaaattcg atcggagaaa aagattcaga agaaggacaa catggacagt
    18721 taccaaaaac cgatccagaa caatatcgtt ataaatctaa cattaattct gaaaatgaaa
    18781 agcgcatttc agatttacca aaacgaaatc aagaagtaca aacggatgag gattccatcg
    18841 atttgccaaa tgataatgga atcgaagttg gaactgaaaa atcaatgaaa attggtttgc
    18901 ctaagacaca aaatttacca atgaaagata gtcgtttgaa tcaattcaag gagaatgatc
    18961 aaagctttgt tcaccaatca actgcaggta ctgttcaaat gaaaccaagt cgtttgcctg
    19021 aaaatggaaa tctgacaact gtttcttaca atttatctga aagtggtgag acagggaatg
    19081 tgtccattca aaatgttgtg acaagagaag ctgcaccaga acctattcaa aaagttcaca
    19141 caggttacaa accagcaaat gtggcattta ctgcaccaac aaaaataaat gtaacaagag
    19201 aaactaaaaa caggaacaat gaattgaaag aacaactatt gagggatatc aaacaggata
    19261 tcaaaccata aaaggcctac gagttaggcc ttttttctat gtatgaaaag gagaaatcat
    19321 ttatggataa atatattaac atgaaaaatc ctccaagatt tagtggggaa tggaagtttt
    19381 tcgccttttt ctttttagat ctattaacgc ttggtggttg ctttttttgg gcgaaaatag
    19441 tcaataatct tgtccactta ccactctttt ttgcactctt gaattatggc ttatggattg
    19501 cgatagctct agtgattgtt tggcgacctt ataataaccc aggtcaacga caaatttttg
    19561 cgattatcga atctattttc tttgcggata agaaccacta tcatgcgtta gatcctaacc
    19621 gaaattatca tggtacgtat aaggaggatg aataaatgcg agtcaaagga caaaattcag
    19681 ttgataagaa atccattttg cagtttggaa aaccagaaga acgatctatc ttggatttat
    19741 ttccttataa atcctgtaca gaagagggag tcttagttac taaagaagat cattttcaac
    19801 gttattatcg tgtagtttct acagacgtgg aaggattaaa cgaacaagag aaactagaac
    19861 gaatgaatca gttgaccacc gtcatgcgta cgtatgtgca aacaattaag ttagttagtt
    19921 tgaccacaga gacggatcta acggaacaaa tcgtacaaaa gcggcaatta ttagataaga
    19981 atcgtatgga acaatcctta ggaagaaatc tacagcgatt aagaaaatat gaaaagaaat
    20041 tagtagagga aatccaggaa ttgaaacgag cagaacaaga acgtcctgac ttaagcttct
    20101 ttttcgtcat tgaaggaaag acaatcaagg atttacaaac cagaaatcgt cagttaatgc
    20161 gatctagtgg cattttaggg ttaaaaccac tctacaaaaa agaattgatc aagattcttt
    20221 atcgaatgaa caatatgaat gatgagtagg aatggagaag agagaatgaa atatccgttg
    20281 atatggttag aaaatgatgt tccgaaggaa gagatcacta gaaaattttc tcacacttta
    20341 agcctgggta agttgggaaa agggcaatct tttaaccaag taaagaatca aacaagaaga
    20401 ggtgactgta catgttagaa gcgattaaaa cagctttttc accacaaaat gatcaaaaag
    20461 tacttgatcc attaaagcaa ctaggaaatc gggaaataga aattttaaaa tccaaagggt
    20521 atgatttaga ttttttaaaa caagtgatgc cacaaggtgg attaaatttc gatgaagagt
    20581 atgtgaccta tggaaatggt tattcacgat gtgtgacagt ctatcactat acaaaaaatc
    20641 ctactctttt ttggttggcc aatctcatga acaatcctca tacagtggcc acactagatg
    20701 ttagcacaga tgaaaagcaa aaagtgattg atcaaatcaa ccgcgcatta gatgaattaa
    20761 atgatcgatc agataatgaa cgaaaagcga ctgaccgaaa taaaagtgcg gaagaatacc
    20821 tggaactagc ggaatatgcc cgaaaattga cttctaatgg ggaaatttct aaacaagtca
    20881 aagtgagagt acatgtttac ggaaatacga tacaagaagt ggatgaacgg gcgcaggaac
    20941 tgatcgaaaa tctaaaaggg atggattatc gtgcggtgac ttatctgcat aaaaccaaac
    21001 gagattggca atcgatgttt accatgttcg atgaacaagc tgaatggttc ggaaatatca
    21061 aagggcaatc actaccatcg ttaaacattg gcggaggttt cccgttccac caccaaacgc
    21121 taaaagatcc aggaggtaca caatatgggg aaaccatgac aggcggccca tttgtctgga
    21181 atgcgacgta taaaaatagt gtacggttgt ctactaatac cttgcttcta ggaatgatgg
    21241 gagctggtaa atcgaccgtt cttaaaatga tcgcggaagc ccatttagct gcaggagact
    21301 ttatttgggg ctttgaaaag ggaaaagact ttattccttt cttaaaggaa tataacggta
    21361 ttatggtgcg tttagacgga tctgacggga tgatcaatcc tttagagata tttgccacac
    21421 ggacgtatga tgaagcatcc aggttatatg acgatggatc agtcaaagat ttgaagatca
    21481 atgaagcagc gtcctatcaa acgcacttag acaaagtagt ctatcaggta cagttagtga
    21541 gtcctcagct aaaaggaacg atgaaagcag aatttaagac ctacttaaat cgtttttatg
    21601 aagagtatgg aacagtacca cgtggcttta cttcctcaaa ttcgcgttca aatactgata
    21661 cgcaagtcac aggtaaagat ccagaagctt atccgacgtt caaagaattt ttagactttt
    21721 taggacaact ggaattacca ggtgcttccc aagagaaaaa gaatcgaaaa gaagaaatgg
    21781 aatccatcgt agaatcctta tgtgagacgt atggcatgat ttttgatggt cacagtacga
    21841 ttcgacacct tgaccaacaa cagttggtct tttttgacat tgactctatt acaggtttag
    21901 atcgaggggt gcaacaatgt caaatgtaca tggctatgac gttgatttgg aatcaggcat
    21961 tgatccaggg aagaagacaa cgacgtttaa ttaaagaaaa acaaatggaa gaacaagact
    22021 tcaaacgctt cttggcgatg attgatgagt gccataatgg tgcgacctgt tctgcagtga
    22081 aaagctgtgg gttgcaagta gtctaaaaac tattgtaata actcttataa cgagaagtca
    22141 aatgagtggg taacgccaca aagggcttcc actgatactc cgacatgcaa caagtagttt
    22201 atgcagacca acgttgtgtg aagctcggtg aagtcggctg aaggataccg taaggtaaaa
    22261 gaaatagtga ataccacgaa agttctttag aggtaaaggg tgtatccgat aagtcgggtg
    22321 tccaaaaaaa cttaatatgg tgagtatgta caaacgtact gacgaactag cgaatgtact
    22381 gtccgaaagg catagctcct agaaatggga gagacagtga gcaaaaaatc actcattgtg
    22441 ctaacttgtg gttgagtaaa agtcgttgtt atgaaagacc atgctgcgtt acaggcgtag
    22501 gagaagttag ggggcaaaag ctagcatcta agttaaggca tgtggataga tataagggaa
    22561 caggggaagc catcaacatg gagagtgcat actcgatgaa gtggtagtaa gaaatatgtg
    22621 aatgacaaat aacttacttt agtgatggtg aaagtagagt cacgactgat gaaggttctg
    22681 taatggaact ggaggaacag gctcgattcg tctgtaaaag tcatgaaacc cgttcaacca
    22741 tgggattctc gtatgactaa aaaggtcacg agccaattgg agcgtgataa accatgacaa
    22801 aagaaacaag tccaaaagat aggaagttgc ggcatgcaga atattatggc atgacggaaa
    22861 tcttcgataa gatatactcc aaaagtttga agggagataa tttcaagaat ctaatgcaga
    22921 ttatcatttc tgataacaac attgtcctag catatcgtaa tatcaagaga aatcacggta
    22981 gtgtgacaag aggagaagat ggagtaacga ttaaagatat tgaaaatctc aaccgtaatg
    23041 aattcgtaga aattgttagg aagcgattcg cacattataa ccctcggaaa gtaaggcgtg
    23101 tagaaattcc taaatataat ggtaaattaa gaccgttggg tattccatca atatgggata
    23161 gaatcgcgca gcaatgcatc ttacaagtat tagaaccaat atgtgaagca aaattcaata
    23221 atcacagcta tggtttccgc ccaaatagat cagcagaaca cgcaatagca gattgtatgg
    23281 cccgaatgaa tcaaagtcac atggaatatg tggtagatgt agatatcaaa ggtttcttcg
    23341 acgaagtcaa tcatactaaa ctcatgagac aaatctggtc tatgggtata cgagacaaac
    23401 agcttctctt aatcattagg aaaatgttaa gagcacccgt agtacttcca aatgggaagt
    23461 tgatataccc aacaaaagga acaccacaag gcggaatact tagcccatta cttgcgaaca
    23521 tcaatctcaa cgaatttgac tggtggatag caaatcagtg ggaggaaaaa gatgccaaag
    23581 agctaaaaca tcattttagg aaaaatggag cttgggataa aggtaatatc tatcacaagc
    23641 tcagaaagag tacaactcta aaagaaatat acctagtgag atacgcagat gattttaaaa
    23701 ttttctgtag aaattataat gaagcgaaaa aagttttcta tgcaactaaa atgtggttac
    23761 aggagcgtct aaagttacca atatctgaag aaaagtcaaa aatcacaaat ctttcaaaag
    23821 aagaaagtga atttttaggc tttacgatga aattagtgac caaaggtaac aaaaaggttg
    23881 ttaatacgca tataggtaca aaagcacaaa gcatgattaa agtgaaacta aaaaaacaaa
    23941 tcaaacgaat tcaaaaaagt cctaatagca aagatacctt tatctatatt ggagtctata
    24001 acagtatggt tattgggatt cataattact tcaaaattgc gactcattgt agtgtagcaa
    24061 tgcgaaaaat tgcaagagaa ctcagaccaa gttttgaaat acgactacga gaacaaggaa
    24121 tctcaaaaga aggacaatac ggaaagtacg aaggatacaa gccttaccta cggtcaggac
    24181 aaatacgata tataagaggg tttccaatat taccagtagg gtatattcaa cacagacatc
    24241 cgatgtgtaa aaaaagaaat attaataaat acaccgaaga aggtagggaa gccattcata
    24301 agaagcaaca aaccgtagaa gaatggaaga tatcgtggtt gtgtagcaat ccagtgctta
    24361 gtaagagagc aacgattgaa tttgcggaca atcgaatttc aaaattcatc gctcaaaagg
    24421 gaagatgtgc agtaacaggt gaggagctta tcttatctga aatgcattgt catcatatta
    24481 tcccttatca tgaaagcaaa agtgatagct atgaaaacct agtgattgtt actgaggagg
    24541 ttcatcgggt aatacacgct acacaaagtg aaacgattga ggaacttcta aaatatctaa
    24601 aattaaatcc aaaacaaaaa gaaaaactca atgagttgag attaaaagtt ggtaacgaag
    24661 aaatatctta ataaatattt gtaggacggg aaaacagaat gtcttttata gacgagggaa
    24721 cgccgtatgc ggtgaaagtc gcacgtacgg tgtggactgg gggaaaagac ggagataata
    24781 tcaaactctt acctatcagt atcgattaat ccagatttta ttgaaacggt aaattatgtc
    24841 acaaactttc aacgagaaat gcgtaaagta gaagcaatga ctgttttagc tacacaatcc
    24901 ccacaagaaa tggtgccaga aaatatgtct tctgataact tctcgaaact gaagaaagtc
    24961 tttgaatttt cttctacgaa gatctttatg cgtatggatg aatctatttt acgtcatata
    25021 gaaggactag tgggtaaatc aatgacgaac tcagaattag aatccattcc tcaacaaaat
    25081 caaggagacg ctgtgatcaa ctttggatca aaagaaacca ttcgcgttca ttttagtccg
    25141 aacaaacgtc aattaaaatt gtttgatgga ggaaaataat ggaaaatcaa gatgaaagtt
    25201 taatcaagca gtatgttaag cgtcgcgcaa agcggcgctt atttttgtgg ttgtttggta
    25261 cttctgcagg tttgattact attttgatca ctgtgtttgt taccctattt ctaatacttg
    25321 cggcgggttc gattgataat tcggattcag attcaagcag tggtggcgaa gcttttacag
    25381 gagaatattc ggaaggctta ccgatttata aagaaatcaa aggaagaggc cctttttctg
    25441 atgagattgc gcaatatgcc gtaggtgcag cagtgaaata taaattatta ccaagtgtga
    25501 ttctttcgca atacggttat gaatcagcgt ttggtacgtc ggcgtccgca agaaatgatc
    25561 tcaactattt tgggattact tggtttgatg gttgtctgtt tcctaaagga actgcacgag
    25621 gaattggtgg cattgaaggt ggctggtaca tgaagtttcc caactcaaaa gctgcattct
    25681 cctattacgg ctttatggta gccacacaat caaattttaa tgcatgtgta ggaaataaaa
    25741 gccctggcgc aagcttattg atcttaggac gaggtggtta tgccgctgca ggaattactg
    25801 aagatagtcc gtattataca ggttgtatgt cgattattac ctcaaataaa ttaacagaat
    25861 atgatgaatt tgcgatcaaa cattggggag aaggcggaaa tgacaacggt acgattactg
    25921 gtgaatggac gaatcctttc cctggcagca gtttagataa aagttccttc agcggtggtc
    25981 aattatttgg aacgaatcca ggcggtgaat tccgtccgaa tggtttccat gatggattag
    26041 actttggttc agttgatcat ccaggaagtg agattcatgc ggttcatgga ggaaaagtcg
    26101 tgtacgttgg aaatcctggt atttcaggtt tgggcgcgtg tgtgatcgtg attaattacg
    26161 acggcttgaa tatggtatat caagaatttg caaatagtac aggaaattcc cgtgtgaaag
    26221 tgggagatca agtgaaagtt ggtcaagtaa tcgggatacg agatacagca cacttgcatt
    26281 taggcttcac tcgaatggat tggcgtcaag cacaaggaca cgcattcaca gatgatggta
    26341 catggatcga tccattacca tttttgaata gcagcaaaaa atagatcagg agaaaaaata
    26401 tggaaaataa aacgttaaaa atcgtcttaa cagctgcact cagcattagc ttaattggca
    26461 atatcgcgct cttttggcag ctgaaagagg aacaagcgac aaatacctat aaaattgaag
    26521 aagtggctaa aaacgcgtct gagaagctca aaaaaaattt ctctgaggca caggcgaaga
    26581 tcgacaagtt aaatcaaacc atcaatgaga aaaaccaaga aatcgatcag ctgaagcaac
    26641 aagacggtat aaaagcaaaa gaagaagtca cagatgccca aagaaagacg gcagaagagt
    26701 tcggtcaatt ggccattgat aaatcactaa gcagaaatga attaacggaa aaactaaaag
    26761 atgtcgcaac ccaagaagtg atcgacaaat taagtcctgc agatgatgat caccaacatg
    26821 atgattatgg aagttactcc tttacattag gtgacgtgca aacttacgct gaaacaagca
    26881 gtgtaaaaga ggaacaaaat tttgtcgtat ttgttgatta tacaatcggc aatcctcaat
    26941 tcaaagatgt caaaccgcaa aaaataaaag gtggattaac tgtcactgaa aaacaagtag
    27001 atggtcaatg gaaagtcaca gactttagtt atttcactcg ttaggaggaa gaaaatgagt
    27061 aagaaaaaag gagcaagaca acgttttaaa aaacggaaaa gttatcttag atggctggga
    27121 atctttacga ttctcggctt tttgattctt gctagtccga tttatacgca taagaaggta
    27181 aacataccag atgaggtaag cacgaacgct tttttaaaca cgaaagaact gacaatggta
    27241 tcaaaagaaa aaggagcgaa tcagcaatta gtttttgaat ttgcgattga cgatgaggat
    27301 caaggcttat taaaagaact ggctaatctt gattatcgcg tagaagtaaa gacagctaaa
    27361 ggtgattatc aagcaataaa agccaaagtg atcaaggtgt ctgatgatta ttttgtagtg
    27421 aaattagcac atgtaccaga agaatatatc gccatgcgtt taaccattgt tcctgaaaaa
    27481 attgatccaa aagtggatat gcaagaacca caagatctga tttattacgt tcacgaagat
    27541 aaggttaagg atcaagtgaa agatgataat tatgaacaac atgcgatcaa ttacaaagtg
    27601 aaaggataca agaaagaaca aaaagcagca caaaaacaga ttgaatcctt gcaagcaacc
    27661 attgatttga atgaagaatt agtgaataaa ctaaaagacc aattgcctta tcaagtcgca
    27721 gatgatcagg aaaatactga aaataagatt aatgattacc agcaagaaat tgaaacatcg
    27781 aaaacgcaaa tgaaagatca agaagagatc attcaaaaaa ttcaagaaaa aattgatcgt
    27841 atgacaaaag aaaatattta gtagaacagg tggagtgaaa gaaatgaagg gagcgaactt
    27901 ggtcggcaaa gatattttcg ctgagcagaa agtattgatt aaagcctatc tcaaagttgt
    27961 aaaagctaaa gaaatatgtc aagaagtgaa tttatctaac acaacaatat ctgagttgaa
    28021 gaatggtaga aagagtttag ataccttaaa aatcagatca tttgaagctt tgtatttagc
    28081 tgctaaaaaa tattttacgg ctgaaagaaa ataaaaacag gaggatttta tgt
//
LOCUS       DADQCX010000033        27839 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.033, whole genome shotgun sequence.
ACCESSION   DADQCX010000033 DADQCX010000000
VERSION     DADQCX010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.033"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(445..1389)
                     /locus_tag="J8R83_001300"
     CDS             complement(445..1389)
                     /locus_tag="J8R83_001300"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAZ9574435.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1685..2629)
                     /locus_tag="J8R83_001301"
     CDS             complement(1685..2629)
                     /locus_tag="J8R83_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9574436.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2850..4064
                     /locus_tag="J8R83_001302"
     CDS             2850..4064
                     /locus_tag="J8R83_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9574437.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4086..6101
                     /locus_tag="J8R83_001303"
     CDS             4086..6101
                     /locus_tag="J8R83_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAZ9574438.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6184..7557)
                     /locus_tag="J8R83_001304"
     CDS             complement(6184..7557)
                     /locus_tag="J8R83_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAZ9574439.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7583..7867)
                     /locus_tag="J8R83_001305"
     CDS             complement(7583..7867)
                     /locus_tag="J8R83_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9574440.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7869..9884)
                     /locus_tag="J8R83_001306"
     CDS             complement(7869..9884)
                     /locus_tag="J8R83_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9574441.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10063..10368)
                     /locus_tag="J8R83_001307"
     CDS             complement(10063..10368)
                     /locus_tag="J8R83_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAZ9574442.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10457..11488)
                     /locus_tag="J8R83_001308"
     CDS             complement(10457..11488)
                     /locus_tag="J8R83_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9574443.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFPLAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11695..12570
                     /locus_tag="J8R83_001309"
     CDS             11695..12570
                     /locus_tag="J8R83_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9574444.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12722..13564)
                     /locus_tag="J8R83_001310"
     CDS             complement(12722..13564)
                     /locus_tag="J8R83_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9574445.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13656..15533)
                     /locus_tag="J8R83_001311"
     CDS             complement(13656..15533)
                     /locus_tag="J8R83_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9574446.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15530..16951)
                     /locus_tag="J8R83_001312"
     CDS             complement(15530..16951)
                     /locus_tag="J8R83_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9574447.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16954..20343)
                     /locus_tag="J8R83_001313"
     CDS             complement(16954..20343)
                     /locus_tag="J8R83_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAZ9574448.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20600..21919
                     /locus_tag="J8R83_001314"
     CDS             20600..21919
                     /locus_tag="J8R83_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9574449.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEEYVVQLLTQ
                     IYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLYAGFRAELQFYSTLLNQNLIYYLSS
                     YIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQYIEEYISDILAVHKIHSETTAITED
                     QLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVSFANEEELIRLFEL"
     gene            complement(21992..22639)
                     /locus_tag="J8R83_001315"
     CDS             complement(21992..22639)
                     /locus_tag="J8R83_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574450.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22647..23333)
                     /locus_tag="J8R83_001316"
     CDS             complement(22647..23333)
                     /locus_tag="J8R83_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574451.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23339..24412)
                     /locus_tag="J8R83_001317"
     CDS             complement(23339..24412)
                     /locus_tag="J8R83_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAZ9574452.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24634..25308
                     /locus_tag="J8R83_001318"
     CDS             24634..25308
                     /locus_tag="J8R83_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574453.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25313..26653
                     /locus_tag="J8R83_001319"
     CDS             25313..26653
                     /locus_tag="J8R83_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9574454.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26802..27788)
                     /locus_tag="J8R83_001320"
     CDS             complement(26802..27788)
                     /locus_tag="J8R83_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAZ9574455.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTYDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8119 a         5256 c         5040 g         9424 t
ORIGIN      
        1 atattataca aagtagattt aaaaaatgat aaacctctct cgaacggttt tttatcaaaa
       61 atcgtcattt ttccatcaaa atctgcttat gcaaaattat aaaaaaattt tgcagttttt
      121 cttacttttt ttgtcgttta attgaatgat aaaaaccagt ttctttattc agttaatcaa
      181 atatgaacga attagatatg aatcattgta tttgccgttg cggaaggatt ttttaattaa
      241 ccacagataa acattgataa cgattcgctt attgtaatca acagattaaa tttcatatgt
      301 tcatatgtac ggatacattt tcggaccgat taattttaac cattctgttt atttgcttac
      361 ctattagata tcaataaaaa actgcttaac agctatttca gctgttaagc agttttagga
      421 tttttagttc atattcattg tttcttataa tacagtgttc aatacttctc ttaaagcact
      481 tgttgatttg ctgaacattg ctttttcttc ttcgttgatt gataattcaa caacttcacg
      541 aacaccattt tcgtcaacga ttgatggcac acctgtaaag atatcttttt cgtcgtattc
      601 accagttaaa taagcagata caggcaatac agcttgttcg ttattcaaga tagcttttac
      661 gatacgtgca gtactcatac caataccata gtaagttgct tttttacgat caatgatctc
      721 ataagcagca ttacggactt tatcagcaat cacatctaat tcatcttggg caatacgatg
      781 gtctttttct acaatttcaa acactggttt accaccgaca gttgtatgtg accatgcagc
      841 aacttctgaa tcaccatgtt cacctaagat atagccgtgg acgctgcgtg ggtcaacttt
      901 taatttcaat gcgatttctt tacggaaacg agttgtatcc aatgttgttc cagtaccgat
      961 aacacgtgat gttggcagac cagattcgtt ccaagcgata tatgtcaaaa tatctactgg
     1021 gtttgaagca acaacgataa taccgtcgaa tcctgatccc atgatttctt ttacgatttg
     1081 gcgcatgatt gacgcatttg ttttaactaa atctaaacga gattgaccag gtttttggtt
     1141 gataccagct gtgataacaa cgatatcagc atctttacat tcttcatagc cacctgacca
     1201 tacagccaca ttttcatcgc cccaagccat accatctaaa aggtccaatg cttccccttc
     1261 tgctttttct tgattcacat cgatcaatac taattcatta gagattcctt ggttgatcat
     1321 tgcataagcg atacttgttc caacaaaacc tgtaccgacg attactactt tacgacttgt
     1381 ttttttcatg aataaacagc tccttttcat aactatttgt tactttcatg aaaagtatag
     1441 tcttgtttat tcattttatc aacatgttaa ttataatagt tgttattata atttttgatg
     1501 gaaacgaatt cctgaatacg cataacagat aaatgacaaa tgtttacacc tatatcccct
     1561 gataatacaa ccaaaagttt agaactgaaa ataaatccaa aaaaattcgc tgcaacgata
     1621 taataagaca gcaatcgcac ctaaaacaat tttccttcat atgctttagt gaaagatttt
     1681 cttcttaatg tttatttctc cattcattgg gagtacatgt tgaatacttc ttgaataatt
     1741 tgaataaaga agtcgtttgt ttatatccga tacgattagc gatttcttcc aacgaaaaac
     1801 tcgtttcttg aatcagttcc aacgcaaagt cgaatttttt ctttagaacc agttcttgaa
     1861 aggaagcatc aaaatacatt ttcaatttat tactaagata gaccggattg tagccaaaat
     1921 gagctgctgt ttcttttaac gtacaagaag taaaatgctt atcgatataa tctaatactc
     1981 taagcatctc attttctgcg catccatctg ctgatgaaaa gctttgttgt tctaataaat
     2041 gagtcaattc gatcagtaat agtgatgtat agagatttaa cgaacggatc ttatgactgt
     2101 atgtatcaaa ataaatcaac agcatatttt caatcaaatg cgtcaaacga cttgtttttc
     2161 cgccgcgaaa atgaatgaat tgtgtatgtt cccctttttc ttttgatgca tttatcaaaa
     2221 aagaagaaag tagattattt gtgcttgcca aatgattcaa tatctctgta gataaggttt
     2281 cttcttttaa taagatgttg attaaaatat cctcttgccc tgtgtattcg attctttgag
     2341 tagcttcttt atcaatgatc accacgtcac tttcttccat ctctatcctt tctccattaa
     2401 taatttgtaa acatgtaccg ctatacatat aattgatttc aacaaaatca tgtgtatgct
     2461 cgggaacttc cgcatatcga cggtgtttac tgatatgaat atttccctgt tgaaatagat
     2521 cccctcggtg gatttttggc ggtgtctgaa gatggtaagc taagtttaaa tcattgatat
     2581 tcattccttg ttcacgctgc agagtttcga ttgattcttc gttacgcaaa aaaaatgtct
     2641 aattcagcta gttccaattg actccctcct ttttgtaagc ggtttctttc gcttattagt
     2701 tcacgctgta ctgctattat atgcaaagct atttttggtt tcataaagac tttctatggt
     2761 tgggacatga acttcctgtg attccgctat tgagagaata accacttcat actatatttt
     2821 tgataagcgc ttacaaaaat gaaaggaaca tgcttatgaa taaaaagatg atgaaatttt
     2881 ctctgctgtc agtctctctt attttgactt ctgctggtgc agtcacgtct gcaattccca
     2941 gtatgtcagc tacttatgcc acgcgttctt tatctgctgt tgaattatta acgactgctc
     3001 cctcttttat ggtcactatt tttgttttga ttagtagttt tattgctagg aaaatcggac
     3061 aaaaacaaac tgtgatcatc ggattagtga ttgcatcgat ttgtggtatc ctccccctct
     3121 tctcacaaag ttacagtatt gtcttagctt caagagctgg actaggtatt ggctttggat
     3181 tgatcaattc tttggcagtc agcatgattg ctgcctttta tcacggagat gaacgagcct
     3241 ctatgattgg ttttcaaagt gcatttcaag gatttggtgc agctttaatg acatttgttg
     3301 caggacagct agtacagttc ggttggcaat ataccttttt agtctacgcc atcagcttac
     3361 ctattcttgt cttgtttgtt ttgtttgttc ctacacctga aacaactgaa cttcaatcgc
     3421 atggcacagc cccaacaaga caagtaatca aaacgaatcc taaaatgatt agttatggta
     3481 tttttctctt gctggtcatc gtggtatata atgctgtatc gattaaatta gccacagtcc
     3541 tgacgactta ttctctagga aacgaaacta atgcagcgaa tatcttaaca atcatgcaat
     3601 tggcaagtat ggctgccgga gtttgttttg gctggcttca gacaaaagca catcgctata
     3661 tgcttacact ttctttacta ctgatgggaa tcggctttgt attgattgcc actgtgataa
     3721 acctgtatgt gattgggttt ggtgcgatcc taacaggaat ttctttttcg ttattcattc
     3781 cttacttatt caaccaagta agtatccaag cgcccaagta cgcggagagt ttcaatactt
     3841 caatcttatt ggttggcgct aatttaggta ctttcattgc accatatggt ttgctctttc
     3901 tctcttttgc ttctcttggg agtaaaacac ttgctgtttt cgtcaatggc agtatcttgc
     3961 tgttgattag cgcgcttatt agccttctag tagtacacag gacgaataga aagacagtga
     4021 taagagtaga tgaagaaata aaagaacaat tgacaacaaa ataaatttga tggaggtcgt
     4081 gtaaaatgac aaatgaaaaa cataaagata gatggctttg gtatcctgga gactttgaga
     4141 tccgccatgg actgctacaa aatttccaac gggaagaacg aggttttgac tggccagcgt
     4201 actggtacat ggatgattgc catcggaacg tcaagtttaa gagatattac tttcttgatc
     4261 aaccttccat gtttaaagtg acgatccaag gagttgggta tgtagaaatt aatggacaaa
     4321 aacatccatg tggaaaatgg ctgacttgtc cagctggtaa agcaaaaatt cgtatctttg
     4381 taggacatac atcagggcta ccagcgatgt ttatcgaggg agacgaagta aaatcagata
     4441 ttggctggac agcaagtaat tttattgaag aatatccagc tggctggagt ccgctttatg
     4501 tcgatatcgc aaaagatcca aatcaaatct attatcaaaa agaatgcgtc catccagtca
     4561 ctgaaacgga gattggcgga ggaatcttat tcgattttgg gcgagcagtg aatggctgtg
     4621 tagaactaat atctctggat gaccatatcg aatctatcac tctatgttat ggagagtccg
     4681 atgtagaagc tatggatatc gattattgct actataagca aataggaatg acaagaaaaa
     4741 tgaaagctcg taaacgcgct tttcgctatt tgtttatacc agaggtttct actggaatgg
     4801 ttcaacttca agtttttcat gaatttttat ctctttcgaa acaagctgct ttttcaagcg
     4861 attcttcttt actgaatcag atctggtcag tatcagaaga agccttcaag ttatgtagtg
     4921 atttgttttt tatcgacggt atcaaacgag atcgctggat ttggtctgga gatgcgtatc
     4981 aatcattcat gatcaatcaa tatctttttt ttgacgagga aatcaataaa cgaacgatat
     5041 tagcattaag aggacaaaat gaaatcaagc agcatatgaa tactatcgtt gactattcga
     5101 tcttgtggtt gattggtatc gaaaaccact atatgatgac gaaagactat gaatttttac
     5161 gcatcgtcta ccctaagatg caatcattaa tgagatactt gatggagcaa acgaatgaat
     5221 tagggtttat ttatgggaga gcaaaagatt ggatatttat tgattggtct gaaatggata
     5281 aagaaggaac gcttgctgca gaacaagtct tattactgaa agcctatcat tccatgatca
     5341 cttgcggaga tatcttagct gaaacatatg gagagaacga aaattatcat actcatctct
     5401 atcaagaaaa atatcaacta ttgaaacaaa acctatttga ctacttttgg gatgaagaac
     5461 ttggcgcttt tatcgattgc tatgaatctg ggagaagaaa tgtgacgcgt catgcgaata
     5521 ttttcgctgt tttattcgat tttgctaaca aagaccaaca gcaatcgatc ttaaagaatg
     5581 tcttattgaa tgacactatc acacagatta ctactccata tttcaaattc tatgaacaag
     5641 atgctttatg caaactcgga cagacgaata tcgtctacca aacgattctt gattattggg
     5701 gagggatgtt atctcatgat gcggtaactt tctgggaaga atacgaccct actcaaacag
     5761 gaaatgaaaa gtacagtatg tatggagatc cttatggaaa aagcttatgc catgcatggg
     5821 gagcaagccc aatctatctt ttaggacgct attttatcgg tttgtatcca acaaagccag
     5881 gttatgaaga atttatgata caacctaatc tagattcatt tgaaacactg aattgtacgc
     5941 tacctatcaa agatggaaag atttcgcttg aaaaaacaaa agataagatc gtgattactt
     6001 ctgatagaac aggcggaaca gtgaaaatga atggtaaaag ttatcctctt ctagcaaaac
     6061 agccacttgt cttaacaagc tattcaaaaa taaatgcata aaacaaaaaa ctgcttgcga
     6121 catatcagaa gactttaaat cttcttctga tattgtccaa gcaattttta ttttgaagtt
     6181 tgcttaattc tgttctttag aaacaatgtt tgttcttttt ccggcaaaaa gaaagctaga
     6241 taatacgaca agtaaaaaga aagcgatgat tccaactgtc aaggctattt gaccgtattc
     6301 tcctagtttc ccaagtacaa gtcctggtac tagataatca gtatcggcaa atgtagaaga
     6361 agcgatttta agatctccta atactggaag gataaataat ggcagccaac taatcaataa
     6421 gctattgaaa gcagaaccta ataccgcccc tcttctaccg ccagtcgagt tgccgaagac
     6481 accagaagca gctccgcaga agaaatgtcc tactacccca ggaatgataa ctgtagtttg
     6541 caagcctatc atagcaaaca tggatagtgt tcctacaaag aagctaacaa aaaagccaat
     6601 taatacagca ttaggtgcat atggaaaaac gataggaaca tctaatgctg gtttagaatc
     6661 gggtacgagt tttttagcaa tcccttggaa tgctggaacg atttctgcca acaccattcg
     6721 aaccccttga aggacgataa caaacccagc tgtgaatgtt ccagcttgga tcagtgcaaa
     6781 gattacagcg ttgtctccat tgcttagttc tctttcaaca aatccaggac cagctaacaa
     6841 agcaagtgcg acatatacga tcgacatcaa gagcatgatc gatacagtag aatctcgcaa
     6901 aaagctgaaa cttttaggaa tctttatgtc ctctgtagaa cggtctttgt ttccaaaaaa
     6961 ctttccgatc catccactag aagcataacc gatatttccg gtatgcccta acgcaacttg
     7021 attgtttcca gtgatgttct tcataaacgg ttgacaaaga gcaggcgtaa tagttaatag
     7081 tgttccttcg aagaccccgc ctaataagat catccacaaa tttgcagtaa accccgcgct
     7141 tactaaaatg actgctgtta gacaagaaac ataaagcatt gcttgacctg taagaaaaat
     7201 gaatttatat cttgtgaatc tagcaagtaa aatattcacg atcatcccta ctagcatgat
     7261 caaagcagta ggtgtaccgt attgttgcaa agcaatcgcc actactgctt cattgctagg
     7321 aactactcct tgagtatgca gagctgtttg gaacatcgaa gcaaaagggg ttagtgaatt
     7381 actgattaaa ccagcaccgc cgatcagtac taggaatccg acaaatgttt tgatagttcc
     7441 ttggatcact tctgaaaatt tcttcttctg aagaacgaga ccaagcagtg caatcaaaga
     7501 aacgaggatg gagggctgac tgacgattga cacaaacaaa ttcaacaatt tatccattga
     7561 tagttcctcc cttgaatcat ttttattctt ttgacaagat cttcgttact ttttctttta
     7621 cttcttcgct gtcaatgatc gattgcaaag gtacgagctt ttcatcaggt atagaagtta
     7681 gcgtatcttt caaagaatgc tcaatgaaga aataatcagc catatcgcta gatacacttc
     7741 caacatccgt atgacttact tcaaactcgt ccacatctgc tccaagatct gcaagtgctt
     7801 gtttgatgtt catctctacc ataaaacttg ttcctaatcc actttgacat actgcaaaaa
     7861 ttttcatatc attcgtctcc ttttcttatg atcgctaata tttcttcttt tgttgatgcg
     7921 tgtaataaat cttgaagatt ttgtttatta gaaagtagct ttgttaaatt tgccaaagcc
     7981 cgaagatgtg cctcattatc gatagcagct aaacagatga acaaactaat gggatgggct
     8041 ggattatcaa gcagatccac aggttgttga agtttcagca aagacatccc tacttcgttt
     8101 acgccatctt ctggacgagc atgaggtaat gcgatgtgat cgccaatatg gataaacgca
     8161 ccatactgct ccacgcgctc gatcatagct ttgatataac tttcttctat tttattttct
     8221 gataatagcg gctgtgcggc aaatgtgatt gcttcttgcc agttttttgg ttgatccgat
     8281 aattggatca tttcttctgt taataattca gatagcatag gacgttgatc ctccttcttt
     8341 tctaaaagtt tgttcatttt acgatttaat acttgataga gcttttcttc gtctacgcct
     8401 tcttttaatt cgatataagg cagtagcgcc gacaacaatt cttgggcaga aggcattgaa
     8461 aatcctggta tcagccaatc tctttgtact tgattgatca gctgattttt ttccaagtca
     8521 gtcatgattg gatgcagaac atagagagac tttttcttat cagtaagtgt gagaggtaca
     8581 gtagaaaaaa taatatcgta agaagtttcg tcaacctcgt gtaagcggtc agctgaatta
     8641 gtctctgtaa aaaagatcat cgggaataat tgctgaagtt cactttttaa gatcaatgaa
     8701 gagctaatgc cacttggaca gacgatcacg gctcttattt ttctatttct ttcttctgcg
     8761 tccgcttttc tgatctctcc gccaaatagt atagtgaaaa aaccaatctc ttcttcaggg
     8821 atgctcttcc ctattcgtct ttctaacgga agtaatgctt ttcttgtcat ttcgtagatg
     8881 gaagcatatt gatgcttaat ttgatcgatc atcacattag gtaaataaaa agaataggaa
     8941 atacgaaaat aggcagggac caagtgataa aagacattca tcaataattc acgaaacgaa
     9001 gcaaattcta cggccatcag gaattccatg cgatggatga cttctgaaga acattccagc
     9061 aaaaaatcaa gtgcaggctc ctggacatct ccttcaacga tcgatgctaa gcaaagagag
     9121 aaaaatataa tctccgaatt ttgatgttcg gaatagccaa ggccagtcaa tacttgtcga
     9181 ctaatgtcag tgactgcaag agaagccaac agttcagcat cttttaccag ttccatggat
     9241 gtttttccaa ttcgaatggt tgtcaaactc aaataataag ctaattcatc cattcgattt
     9301 ggtgcgaatc gaagatctga tagtgaaatc gttttatcta gcaaatctct aactttggcg
     9361 taataatcaa tggaaagggt tgcggttaaa tacgtgagcc caaatcttcc agcaagtgac
     9421 tgcatcaaac gagcagtgcg attttttgct tctcttctta atattgcttc tgaccctagc
     9481 agcctaaaac cagttttcct agtatacgac agctgacaat cttccacttc taattcattt
     9541 cttatctttt tgatatctga caggactgtc cctttagaaa cctgaagaaa atcttgaaaa
     9601 tgaaaaacag aaacagacgt tgcagtcgaa taaaccatca aataaagaag atctcttcgc
     9661 tcttgttcgg tatacacagc ttcaaatcga gtaatatcca aaaatttttc tgcccagtcg
     9721 attgctcgga atttctttat acggatacgg gtatcatcca catattcggc aaaaggagtt
     9781 aattgtttga tcgcctcgct tgtatttact tcgatgatct ctgctgcttt ttctagactg
     9841 atttctcttg gtgttttcag gagataacta attttgtagt tcacagcgct gttcacctcc
     9901 tacttatatt ctagtatggt agcgctttta aatcgagggg tgtttggtac aacttacagt
     9961 tggatttttt ttacgactgt accgaacgat ttctatcgaa tggatacaga aaaaaagcag
    10021 gtgaccaaat gtctcctgct tttatgaatt gatttcgtcc gatcaatgat gatcatgttt
    10081 attttttgag gtcagttctt caaatttttc tttgacatct tcaaccgctt tttcgatatc
    10141 tttttcaaag tgattgggct cattaggctt tgtttcctct tctacagaat ttgaaccaga
    10201 taaagctgtt tctttatttt ctgtttcacc agagtttgtg ccagctaatg attcttcttt
    10261 gtcttctgtt tcaccagaat tagttcctgc taaagccact tcttcttctg ttttaggggc
    10321 cattgaacct cttaatcgtt tgtgtttttc accgtcataa tttgtcatgt tggttcctcc
    10381 tagtagttct atactttttc atcgtacaat aagacagttt atgcgtcaaa aaacaaaccc
    10441 gattcttaca aatatgtcat atttttcctt ctgattcttg aatgcttttg attccttctt
    10501 ccaaaatttt catttgtaag attgtttctt catctttgat gactttttct gcgccattaa
    10561 ctaatgtctc gtaaatccct tcgtagacac ggctgtaatc accaacctcg gaaattactt
    10621 tttcttcatg ataactccct tgttcatcta tataggtcaa tacaccataa tgttcgggca
    10681 aatcgatacc aaagtcttca tgatcaggca tgtaaaacat tttcagatgt tcttcttgtc
    10741 gatcttttgt ttgtttcacg aacatccctt tttttccgta aacgacgaaa cttggacgtt
    10801 ctttgatgcg gaaataacta gattttatcg aaattttcat atttccatag aaaaaatcca
    10861 gatcgaagta atcattcatt cgtcctttcc ctaaaagttg acgtacatca tagctgatat
    10921 catctggttc gccgaaataa gaaagaactt gatctactgt atgacaagca tgtccatata
    10981 aatagctgtt cgcagtagaa aattcatgcg tattttctgg tacttccggt ctgaaataat
    11041 cataatgcat ttctacttct aaaatatccc ctaattttcc gctttcgatt actttttgga
    11101 ctgtcaagaa gtcagaatcg aaccgtctgt tttggtaaca ttggataaat agaccttttt
    11161 cttttgctaa tggaaataac tcttctgctt cctttgacgt ttctgcaaaa ggtttctcta
    11221 ctagtacatt cttaccatgt tcgagtgcca tttttccata ttcataatga aattgactag
    11281 gtgtagtgat gacaactaat tggatctcag gatcatccca aagatcagac agctgatcag
    11341 tatattcgat gtcttcgaat gttttccaca ctggttcaga tggggaaaaa atttttttga
    11401 tattgatttt gttcgtaagt tttcttgaaa aaggcaaatg atagcgattt gtactctttc
    11461 cattgccaag ataagcgatt gtaagcatga gtggtgcctc cttttattga tgttttcagt
    11521 atatcctaga aaagcgcaga aagtatttat aatagctatt ctggtaaaaa agttcagaaa
    11581 aacacttgtt atcattcggt ttggtgaaat taatgttcaa agtaaggata aaaatcaaaa
    11641 agatagtagc ggaaccaagt gtttatcagt aagatagaat ttggaggtca gatcatgctt
    11701 attgaagaaa aactaacaaa acaagagttg tttaccacga cagagaaacg gattgtcgat
    11761 tacatccgta ggaatatcga agctgcagtc tacatgacga ttgaagaatt agcaaaagct
    11821 acgtatactt cccattcagc tatcattcgt ttatgcaaaa aaatgggatt cagcggattt
    11881 aaagaattcc gtttcgagct ggggcgggaa gttcatcaat tgattgctca gttcaatcaa
    11941 acgattgatc ctaattttcc tttttcaagt gaagatagca ctcagcaaat tgcaaagaaa
    12001 atggcggatt tatcgatcca gtcaataaaa aaagcacaat tgcagattga acatgaagat
    12061 ttagatcaaa tcggtaaagt attgaacaag gcacagcgaa tctttctttt tgcaaaaggt
    12121 gattctcaaa tcacggcaag gaaattccag aataaaatgg tcaagttgaa taagtttttg
    12181 atcatggctg aagaatacag tgattcttct tggaatgcag ccaatttgac tagcgaggat
    12241 tgcgccattt ttattagcta cagcggtcgc atccatcatt atgaacgaat aatgacctat
    12301 ttgaagcatg tagaggcccc taccttgctg attaccggaa atcagcattc agaaatggcc
    12361 aaacaggctg atatgtgtct tgttatatcg caggaggaat atgattttgc taaagtagcg
    12421 actttctcct ctcaaattgc cttcgattac gtattaaata cgttattctc agtgatatat
    12481 tctcaaaatt ttgaagagaa tatccgcaac ttgaaaaaca aacaagaatt gatgcaaaaa
    12541 ggccttctta aagaatatcg gaaaacttaa gaaaagatcc tcatttagta ataagaaaga
    12601 tagtgtttga taggctctct ttgatatcat cataaaaaca ggctgaagtt ttctttttca
    12661 aacctcagcc tgtttgttta cggaacgatt cgaatagata tattatagaa atgaggaata
    12721 gctaacttct gtttcttatt ttgaacgatt gacgaaaaag atatataaga aggaggaaaa
    12781 tcagtataca tgcagctaac aatccataca ggaaaaatcg tttgttctcg gatactttct
    12841 gtacttcttt ttgaacttct tttgcatgat aaggaacccg gtgccctctg acaagtaagc
    12901 gatgactgtt gaccatataa ggtgtacaag ttaggagtgt cacgaaatcc tgcccttttt
    12961 cgattctcag atcttttgta tcagtcggtt ctaccgtctt gatctgatcg acttgataag
    13021 cgagtgtccg tccattgatt tcgatataga aagaatcacc taaagtcagt ttcggtaagt
    13081 ctgtgaacaa ctttgcttga ggcagtcctc gatggctgga aataacggca tgtgtatttt
    13141 ctccccccgt aggataagac gttccttcca ataatgaggc acctttttct agcagcacag
    13201 tattcgtttc atcaaaaatt ggcaaatgga cattgatctc agggatcgtc aaaataccga
    13261 tcgtatgttt ctcaaaatag gttctatcct ttttcgcagg ttcttttttc ttagtaaagg
    13321 gatctgcacc tggatttcca ccttcttttg ctaattgctg gtttttcttt gtcatgtttt
    13381 cttggatttt agccatgact tcttcatttt ctttgaccgc ttgttgctga taatgagaga
    13441 tgatctgctg atccagataa ttattcagcg cgtcgctaac aaatggataa gctagtatcc
    13501 ctattcctga gagaagcaag aaaagcatca gcagatctag aagtttcctt ttctttggtt
    13561 tcatttgtgt tctccttgtg atgactgttt gataataaaa gaaaaaggag catttgcgta
    13621 atccgctgct cctttttcca attcttgcaa aaagactaaa tctgactgtg cttgcgtcta
    13681 gcaaagtaca gtccagcaat cagtagaagg actactcctg caccgatata cacatagatt
    13741 cccttaccgc ctgttgaagg aagtgtacct ttgtgtttat ttggtatttt ttcaggagaa
    13801 atcaactgtc ctgctgttac ataagattgt tcatcgatag taaatgctac acggtttgtt
    13861 aatggaacat atttttctgg cgctttcgtt tcttccagat agtacgtgcc atattttaga
    13921 cctgtcacat cgattaaacc gttacttgtg gttgtaaaaa ccgttgctga ttctttcgcc
    13981 gatacccagc tgacggcttt tgtggatggg tcgatcgata aatatttcgc tgtgtcacta
    14041 tcttgatcac gaacgacgaa ttctgctcca gcaagtgttt ggtctgatgt aacgtcacca
    14101 tctactttaa caaatcgttt gcccccagta acgacatcga ctgacggtgg tgtttgatca
    14161 tttgtatgcc cgttatcgac atttgcttgg ttagaaaatc ctttggttgg atctgctttt
    14221 tcgttcaaat gcatatagta aacgaatttc aatgtaccgc caggagttaa tgaaggaata
    14281 taattcggat caactgaaac cgtgaatccg tctgtttgct cagtgacaga ataatttact
    14341 gggtcgattt ctttatttcc atcatataag gcataagcat acgttcctga agaatcatta
    14401 tcaaatgtta aagcagcgtc atgagtatcg ataagtttga atgttgtgta cttgttttgc
    14461 gttccttctt tatcagcgat acctaatggg atattgacag aaatctcata ttgaattttt
    14521 tcaccgattg cgacatcttt tccattcaat tgaggtgttg ttttatcaac tttagacgta
    14581 tcatttttga tggtcttttc tactggtgtt tggctatttg ccaggatctc aaaaggcgtg
    14641 attgtttgct tttcaatcat ttccgcatta tcaggagctt ttacttcttc taaattatat
    14701 tttccaactt ctaaatgatt aacgatcaac tggccttttt caatagatgc ctcggcaaag
    14761 tcattgttgc cgatgtcata agaatgacca gtaatgaaat gtttggcttt ggtttgatca
    14821 gttgtccaag tgtacaatcc atctgtgaca ctttggatgt attttttgac gcttggtgtt
    14881 ccttcttctt tagaaataat aaattctgct ccatttagtg cttcgttttc ggcagtaccg
    14941 atttttgtaa ctttcaacgt tccatcatta ccgactgtat ttttagggta gagatggata
    15001 gtatctagtt cttctgtccc gtatttataa gagccatctg cttgtttgat catctcatat
    15061 acagggaaag ctaaaaccat gtttgcggca gctgacactc cgtcttttgg ttcttctttg
    15121 atcgtgtaga ctgcatcttt cccattttgt tttttaggta aagataaagt gacatttcca
    15181 tcagcatctg tcgttcctga agcaactggt gtaccaggag tcaaagactg gactgcttgt
    15241 tttgctgcat ccacggacgc tcctttatct cgttgcgcat aaaattcttg agtgacgtta
    15301 taaactgaaa atgaaatatc ggctaatcct tggtattgat cgaattcgct catttctttc
    15361 ccgctgtttt ggattaaagg atcgggtaaa tcagtcattt tctttttatg aaggatgact
    15421 tgagctgctg tctcctctgc aaacactttt tttgcgccga agctgtttgt gagtaatggt
    15481 aaaataagga aaaggactcc taacataacg tttatttttt tatgattttt cattttttca
    15541 ctcctgttct ttttttgata aacaaccaga ttgcaaagct tgcgaatacc ataccaacaa
    15601 cgcctaaaag tgtatttttc gtttcgtttg tttttggaag aaatggacgg ctattttctt
    15661 ttttattgac tactttcaat atactgtccg cctctttatc ctcagaaaga aaagttgaaa
    15721 tggtaaacgg aatttctgtt tcacttaaaa tataaccaga aggtgcttcg atctctttta
    15781 atcgataact tcctgttttc aacccggaaa ttgaaaaagc gccattttta tcggaaatca
    15841 ggtgaagcgc atctgattcg ttctttgtcc acttgtatcc gttggctgtt tgctggaggt
    15901 aatttcctgc tttgttttta ataaggaata ctgcgccagc taatcgttta tctggtttat
    15961 ttgtctcgat tttgacaaat tgcttactcc ctgtatatac agagactttc tttgtactga
    16021 caccaaaacc aaaatccagt gttccgttgt tgttgatttc cttgttcgcc tgtgctgtac
    16081 tgcttagctg catctgataa gaaatggtca gtttttttcc agcatatttt tccaacgaag
    16141 ggatcgaaaa taaaacatca aatccgtgag gtttcttgtg tatgacaaag ccttctgtca
    16201 gcttttctcc attcgatgaa atcgttaaac tattaggtaa aaacgttaat gcttcatccg
    16261 cactatctga caattcgaac ttttgatagt caaggatatt tacaggaatt gtcgtatgca
    16321 aggaataagt gattttttca ccaatcgtaa aatcatttct aggctcttct aataccttct
    16381 caaaaggtgg atcagggtag tcgttttctt catttttagg atacaaatgg atagttgaaa
    16441 gtttttgatt gttttgtcca tgtacaggaa gaacaactac catattctct gccttttctt
    16501 tgacgacttc tggtactttg gattcaatga aaagatacgc tttatctctt ttttcttgat
    16561 ctttagcggc cagagaaaaa gaagcgatac catcttcgtt gttaagagtt gtagttgttg
    16621 cttctgcggt aaacataccg gaagacgcac cgttttttgc gatctctgct tgtgcttctt
    16681 ctaccgtttt gcccttttcc cgtagatggt aaaaagaatc tgtgacatca taaacttgga
    16741 atgtgacacc atttaatcct cgatacgttt gtaataaagc tttttcttgt ccgtcatttg
    16801 gatgattttt cggcagttgc ccgtttggga aaagcaattt gtgtaaagta atctgaacca
    16861 tttctgtttc tgtttctgtt gctacctgag taaaagctgg tttaaatagt aacaagaaga
    16921 gacacatact aagccaacca agttttttca tatttagctg ccccctcttt cttttttcaa
    16981 aaaaagatac caaatagaaa acgcacaacc aatcatccct actagataga ttcctaaacg
    17041 gccaattcct cccgtttcag gtaatggtac ttttgcctga ttcgtgatgt ctaaagaaat
    17101 ctggttgttt ttggctcctg gtgacagaac agattcatga tcttgtccat ccacttgaat
    17161 tgacccatct tcgtgtataa ctatagtaac tggctctttt agaccttggt atccttctgg
    17221 tgtaaaagtt tcggtcagcg tataagttcc aggttttaaa ttttcgaata gaaaggtatc
    17281 tgtttcttgt ccatcttttg gcgattctaa gtccatttct ggtccctgca gtctgaattt
    17341 tgctcctttt aatgtctgtc cgttgtcttc ttttttgtgt accgttagat caaacgcttt
    17401 tagtcgattt tgatgagtga gcgtccatac attatttgtc atctcggtat tttttcccgt
    17461 gtaaatgatt tttccatatt tatcgatttg gaattcataa tttcccggcg aagtatcata
    17521 tccggcagga ccagctgttt caacgactcg atatttacca ggtgtgagtg aatcaaaact
    17581 ggcaagacct ttttcattcg ttgtttggct gtcaattggc tgataagtac catttgcttc
    17641 ttttttctgt agggaaaatg ctgctccttt aagatttatc tctttgtccg tcccttgcat
    17701 cgcatactta cgtactgcta caggaacttc aacaaaagga ttttcaatag tcaactggat
    17761 cgtatcatcg gaagtagtga ctgtttttcc atcaatggtt accgtaccat cagaagcgat
    17821 cttgatttcc caagtagtct ttttgcttaa tccatgccct tctggagctt ttgtttctgt
    17881 cagcgtatag gtcatttctt tttgcaattt gacattttct ggaagagaat aggttccgtc
    17941 gccatgatct gttagtaaag tatcaataga atctcctgtt aatttgaaaa cagcgccaat
    18001 aagatccttt tcacctgtag aggaattttt cgttattttc aagtttaacg gtgtgaattg
    18061 tttagtattt ttccatgtca ttgcatctat ttgttgagaa tcgtatcctg gtacaggtaa
    18121 ttctttgatt gtttggtaac tgaatgcttg accttgatta ttgtattgag gtagtgataa
    18181 tatctcttga taactttctc cgctatttgc agataatttg tcaatgtctg cacgttccca
    18241 cgtatttgtt gtatctttag ctggtttaat gattcgaata tatccgtttt tccaagctgc
    18301 agcatttgtc gtatgttccc gttgaatctc aaaagtaact tgatctggac gatcagctag
    18361 attgttgtca aattcttccc ataacttttt gatgtgaaga ctgactccgg gagctttagc
    18421 agatggtata ccgaattcag ctaattcatt ggtatcaatg tttggctgga aagttgtcct
    18481 gccgttcatt tgataccaga aatttggatg gaagtcctca ttttctgttt ggattctcac
    18541 ttggtaatgg atttggattt cttggtcttt tcctaaatag atctgattgc tcttgatggt
    18601 atttccttct atggaaatag atggagtgac cgttgtagga cttgtcccca cactcttgac
    18661 tgaaagtgta ccaggctgat aaatgaatgg ttctgcgatt ggatcattta tttgtccatt
    18721 gcttacagtt gctgagatct gtacagcttt tttggctagg tattcagaga tatctgttgc
    18781 atgatcagct gattcatagt aaagatcgcc tttttcatct gatgaaacca tttgtcgcat
    18841 acgagactct acttctgctt ttgagagacc agctgccgga tcgctttgaa gttggatgcc
    18901 aagaccatgt atttcgattc ctcgttcttt gagtgccatc gcttctccga tggttgcgat
    18961 aaacgtactg tcgattcttc tggatagatt gttttggtca ggtgcatcat agattcttga
    19021 gattagagaa gtatttcccg gccgatcttg cgtattagaa aactgagttc cgtaataatt
    19081 gctgcttgat tgtgcgtgta cccgctgtac tttataggaa aatgttggta caccatccgt
    19141 cagcaaaacg atcacttttt tatgtccatt tggaacggat agcatgcttc ctgcatctct
    19201 tagtgctttt tgtgtaaaag taccaccatt tgtccgtgaa ggtgtaatgg attttacttg
    19261 atttttcact gaatcaaatg aacccatctg tactgcaccg ttactgtagc tatatccttc
    19321 gcttgagtag ccgacatatc ccatattgat tttgtctgtg ataccgctat ctgctaaagt
    19381 atcgacaaaa cgatcgacac caatctttac ttcaccgatc cgattattgt cgttcatact
    19441 tcctgaccag tctacgacca atacgagatc aagaggcgtg atatcttttt gtacatttcc
    19501 acgagcattc aaataaacat caaacaatcc gggtgtactt gtttcctttg catactttcg
    19561 tatcgcatag tctgcttgat taccggttcc tccatattcg atatacgaat gggtccgatc
    19621 attaggatct ccattccaag aatttatacc atcccattga tttgttccgt ttttattgcc
    19681 ttgatgatca agaacatttg tatttcctgt aggttgccaa ctggctttag gataagtgcc
    19741 ctgatcatct gttgtatatt ctgtaggaat cgtttgatta gatggcacac tcacagctgg
    19801 caaggataat gtaggcaatg taaatgggct gacagaattt tcgttttctt ttgatgattc
    19861 ttcttctatt tcgtctggct ttggtactga cacatctgta tctttcttat tttctgtctc
    19921 atcaataatg tcatattctt tattatcgac gatcagcttg tttgcctggc tgtggtaaag
    19981 tgctggatcg attggaaaac tcagatcgat agtttgttta gtgtttgatg agatttccaa
    20041 cgtaattttc ccgctattta cctgataagc atagccatct ccttcttttc tttccacatc
    20101 acttaagtaa ttttcgacta gaccaatttc tttttctatc ttttcagcac tggtgttatt
    20161 cgcatttagc ttgatgttca gtgctttttt tccagactga tccgaaatga cttcagctga
    20221 aattgtttct aaaactgttg gatcatctgt agtgtctgct attgcagata atggcacaaa
    20281 gtttgataaa ctcaatatta tcagcatgaa aataactttc agtttcttcc ctgtggtcgt
    20341 catttttccc ctcctttttc tttttttctg ttttgacgtg aatagtgaaa attattaaaa
    20401 taaacaggcg ttacataatt ttatttattt taatatgata attattatac gaagggcgct
    20461 aaagggaatc acaccaattt tcataccaat tggtttcatt tatgaagttg attccttcga
    20521 ttaatgagcg tttcattgaa agaaaagggt tgagggagaa aaacatatga tcaggttgtt
    20581 ggaatgtaac tatagaaaga tggaaaaaat cattcgaatt ctgtccattt ctgacaagtg
    20641 gatgactaaa aaagaacttg ccaaacgaat tggtagttca gaatctacat ttgtaaggta
    20701 tatcgaagag atcaaaatcc gctggggaac ggatgtaacg attcaatctt cacaaaaatt
    20761 ggggtatcgt cttgaacatt tgaatgtacc agcttattta aatgttctga tggaaatgtc
    20821 gcaaagttct acaaacagtc gtttattaaa tgagattatt gtcaatccgg gtaaaacgat
    20881 tgagtattat tgtgaaaaaa tttccatcag ccggtcttct tttacacgta agttgaaaca
    20941 atgcaatcaa attttagaaa gctatttatt aaaagtgatc gttgaccaag gttttcagtt
    21001 aactagcctt aaaagtgagc tccagttgcg tatctttgtt acctttttct ttttaagtta
    21061 ctacggaaga cgcacgttgc catttccaat cgaaaaaaag aagatcaaag aaattatggt
    21121 caagaataat tgtcagatga atttgtttca ggaagaaagc ccatatgagc aatctttctt
    21181 tattatgtat tttgttgtgc atctcatgag agaatcccaa ggaactccat ttgaatggaa
    21241 agctggagac tcttatgtac agttgataaa tatcgataaa aaagacttct taatcttgaa
    21301 aaatctctta ggaaaattga agtacagcag ctatataaaa gtagtgaact attttgtcaa
    21361 tacgattttt tcagaatttt cggagaaaga aaaaaacgaa gaatatgttg ttcaattatt
    21421 aacgcaaatt tattttttct cccgtatttt cccatacgat acgactcatt tgacgatccg
    21481 tgcaacttac tttgcacagc agatgcaaca ccgccagata cgtctatatg ctggatttcg
    21541 tgcagaactt caattttatt ccactctact gaatcagaat ctgatttatt atttatctag
    21601 ctatatcttt tggatgctta tcggtaatcc tgaaattcac cattatactt ctgataaaaa
    21661 aatactgatt atcagcgact taagtcttcg acatagtcaa tatattgaag aatatatcag
    21721 tgatattctt gctgtgcata aaattcactc tgagacaact gctattactg aagatcagct
    21781 gtcgaaatac aatcttctcg agtatgatct gatcgttacg aatcaaccca ttttgaatgc
    21841 ccatgttcct catatattga ttgatgatag tgtgtcattc gcaaatgaag aagaactcat
    21901 ccgcttattc gagttatgaa taatcaaaaa acagctatgt ataaaccacc ctgataaaaa
    21961 tttcaggaca aatacacata gctgtttctt tttattgtat tccttcagca atccaacgag
    22021 atttatagcg aaagtctttt aacaactctt cttttgtcca attatttgca atgagatccg
    22081 tcaaagtgtt cattacgagg gtcatggaaa agtataggaa actaactgct tcttccgacg
    22141 attgaatgga gaaatgattg attcttaata attccagcca tttttcgttc attggagaat
    22201 cagccgatag ttctctacgt ttggttgtct gctgatcatt tcgctgggtt aacaagtata
    22261 acctttgcca atagatactt tcgtgatcta agtcgcagca ccactctaaa tatttttcga
    22321 tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt taagatatct tgatggacta
    22381 tgtgagaact gcttttgatc gtatacaaat aagcatcttc caaatcttga aaatatttat
    22441 aaaaagcacc gcgcgacatc cccatcttgt caacgatttc tgagactttg acttggctga
    22501 tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat tctctgtttc tttgcgttcg
    22561 ataaattgaa aaaagtttct tttggcatcc acatctctcc tttatctctg attatacgtg
    22621 gatagccctt cattgtcatg aaggattcat tccttctttt tctcttcttc tgtcaagtac
    22681 ccatcttcca ttcgataaac gcgatcactc cattgaatca tacggacatc atgagtaacc
    22741 ataatagtcg ctttttgttt ctcatgagct tctttaacta gtaatttgac gacttcatat
    22801 gcatgatctg tatccaaact agctgttggt tcgtctgcta agatcaagct tggctcatta
    22861 tataaagcgc gagcaattgc cactctctgt ctttctccac cagaaaggtc tttaggataa
    22921 ctatttttaa gtgactggat atctaaagat tgcagcaagg aatcgatttt tgttgaatct
    22981 tctttttttg aagtaacttg gtcaactagt tcaaattgtt cctttaccgt taaaaaagga
    23041 atcaaattag agctttggag aataaatcct atttctttaa agcgtaaatc tgctcgtttt
    23101 ttttctggaa gctcagttag tgagtgaccg ttgatcacta tttctccgga agtcggtgtt
    23161 tgcaatcctc ctgaaatggt aaggaaagta cttttacctg aaccagaagg accaatgatg
    23221 ctgacgaatt ctccttcctt tacataaaaa tcaattgctt tcaaagctga gacctttgta
    23281 tgaccagaac caaatgtttt ggtaactttt ttcatcgtta atattttttt catttttatt
    23341 aacctcctat tgctgtaatt gggtctactt tggttatcgt acgtatcgaa aacaatccgc
    23401 ctagcattgc gacaatgatc aaaatcccac tatatagcaa ccattgtgac caaaaaacag
    23461 caaaaggcat cgcgcttggt aaaatcagac tagtcaaata agcaaacaaa agagcaagca
    23521 gaacgcctac caccccaaca ataaaggact gtgctactaa agatttagcg atgaagaaat
    23581 ttttgatccc ttgtgctttc attactccaa aaatagcagt cttctgaagt gtcatcacgt
    23641 acatgaaaat accgaccacg gcagcaacca ctaagaacaa aaagtatatc atcgcattta
    23701 aggtcatatt ttgggcagaa tagccaggaa tactttcaat gaatgtccca atagttaata
    23761 actgtagacc cttcgatgct ttttctttcg aaattttagc tgaatccttt attacgatcc
    23821 cattgatcgg ctgttcttct tcagaagcaa acggctgttg tccatacttc aaagcagtcc
    23881 acgtatctag ggacgcatag atgacgggag aaactgtgta ataagtttca ggaaagatac
    23941 cgacaatcgt caaaggatcg tcgtaactgc caattttgat cgtatctcca attttatagc
    24001 ctgaatcagc cagattttga gagatgatga tttcattctt tgttttaaat tcatgccctt
    24061 tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc gaaaactgta acattttctt
    24121 tgttttttcc tttgattgct ccgctgtaca atccgattgg tgctttctct cctccttcaa
    24181 tgtatttcag atctcctctt gttaattgtg aagctgcaaa tacttgattt gcatcctccg
    24241 acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt tttaaactct tctgaaagtc
    24301 cattcgctag tcctgacaac atgaatacga catacgcaat caagaacata ataccgacga
    24361 tcaagccata tcgtaattta gaatagcgaa tttctttgat agctagaaac atttgttttt
    24421 cctccctatg atagattgat agtgacaaaa tgtcacttgt tgaatagtgt aactctaaag
    24481 tgacaatttg tcacttgtgt tgtttttttc ttatcaataa attgtctaag acatctttcg
    24541 ataaaacctt aacatgagtc ataaaaaatt tatttaagcc ttatttatgc tttccatgat
    24601 aaactaaagt gaccaaatca atgaggtggg aaaatgatta aactattagt agtagaagac
    24661 gataaagtat tatccaataa tataaaagaa atactcgctg caatcggcga gataacacaa
    24721 gtttatgatg gtagtgaagg actgttcgag ttggaaagtg gagtttatga tcttgcaatc
    24781 ttggatttga tgatgccgga aatgaatgga tatgaagtgt tagcaaaaat acggaaagaa
    24841 aaaatacaga ctccagtatt gattttgact gcaaaagata gtttggaaga taagattgaa
    24901 ggatttgaac gaggtgcaga tgattatcta acaaaacctt tctatcgaga agaactgatc
    24961 atgcgcgtga aagcattatt gaaacgctcg ctaggtctct ttgatgaaaa tgttctgaag
    25021 tataaggata tcagttgtga tttaaaaagc aatgaagtct tgtataaaga acaagttttg
    25081 cccatacaag gaaaagagtt tgaattgctc gtttattttt tacaaaataa gggaatcatt
    25141 ttgacaaaag agcagatatt tgaccggatc tggggatttg attctgatac gacgattaca
    25201 gttattgaag tttatatgag caacttacga aaacatctgc gaagtactgg attggataaa
    25261 gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa gggtgtgatg caatgaatgg
    25321 agatattaca cgaaagcaac gtagtcgctt ttttgcgaca aatgtagcag catttgcttt
    25381 tatctttttt cttttgggat tcattacttt acagatatta aaccaatctg catacagaga
    25441 aacagatctg tcattagaga aaataaattt tgattctcga acagtacaat tagagataca
    25501 aagatatcag caaggcgatc cctttttaaa cccgactcaa acggaacaaa acagaacaaa
    25561 catggaacag ccattaatgg aaccatcaaa tgaccgtttt aacactcaag tgatcttgtg
    25621 gtctaaaaat ggtgagatat tgaataaagc agctattggt gggcgtttca accaaatcaa
    25681 agaattaaaa atggatacga aaaatctgaa taccatccaa aatattgaat taaatgaaga
    25741 cagtggctca tctgccctct ctttccgttc gattacgaaa aaagcggaga cgaatcaaga
    25801 tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa atcaagaatt cattagcgac
    25861 ttttcgcacg attatgattt tgtgtatgat tgttttttgg attctctcta ttggtatcag
    25921 ttattacttg tctagtctaa gcatgcgccc tattattctt tcttggagaa gacaaaaaga
    25981 atttgttgag aatgcttctc atgaattgcg cacaccgtta acgattattc aaaatagttt
    26041 ggaacatctt tttaccaagc ctaatcatac tattattgaa gaatccgaaa gcatcgctca
    26101 agcattgtca gagacgaggc gcctcactgg attgacttcg gatttgctga caatcgctcg
    26161 gaatgattct gatcagcagc tgctttcaaa gcaaatgatc aatacacaag aatatatcga
    26221 acaacttgtt aaaccatttc aagagatggc catcatagat ggaaaagagt ttattctcca
    26281 taacgatgca acattagaag taccaattga tgaaaaaaaa atccatcaag ttttggttat
    26341 tttgctggat aatgcattaa aatatacgaa tccagaagat aagatcattt tggattcatc
    26401 tgttaaccat aaagaatggc tgattcacgt aaagaatact ggcccttcta tcagtgaaga
    26461 agatcaagca aggatttttg atcgatttta tcgggaagat caatctcggg cgaaagagac
    26521 tggcggatac gggcttggct tggcaattgc aaaacaggta atcgaacagc atcatggaca
    26581 gatttctgta tccaattatc ttccacaagg agtcgatttt aaagtccaat tgccgttgaa
    26641 gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac aaaaatcttg tcacagccct
    26701 tttttgttgc gaataaacgg tgttccagaa gtagcttctt cggaaataag ccgaaatttc
    26761 tttaagctga ccacttctgt cacaacctct ttagcttacg cttacgattt tttattgcgg
    26821 tcttcaatgt gtacatcacc gcttgtgtca atatccaatt cttctcggct aacatcttct
    26881 gtcacttttt caacatcttc atgttcttct ttatgaatcc caacttcttc acgaataact
    26941 gtatgtttgc ttacatctac ttgctcttct ttgattggga tagtaatcgt gtcatcttcc
    27001 aatttttcgt ctgttccctg tgaagattga tctgttactg gtttgcgttc gatgacgatt
    27061 tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt tgaccacatg tttgtggatg
    27121 tcgacttctc cagttgtcac atcatatgta tttacatcta atttttcttc ttttagttga
    27181 attgtatcat catctagatt tggtttgcga tcgatgtctt cagtcttgct tgtacccatt
    27241 gtatcagtct cgccaggtac gtccatcgga tcagttcctg gtgtcatatt caatggatcc
    27301 gttgtatttt gaaagcctgt cgtgccacct acgtccattg gatctgttcc agtgccagtt
    27361 tctaatccag tccccattgt gcttgctggg ctaacagtat cttgtgtatc cattgtatct
    27421 tctgttgttt ctggctgacg atagcctttt actgtgatga caaattttcc atcagaaata
    27481 tctcctctat attgatataa aggatcattt tctggtgtag ccgtctcaga atcataggta
    27541 tcaaaagaaa aagtatcttt tattttttcc cataaagaac ggtcttcttc accatccatc
    27601 cgattttcat ctgtttcaac atctatacca gacaatccgt caaatcctag tctagatgct
    27661 gcttcatcag tagtataaat aacgatatca tctcgttcat acccttcgtt acgcaaccgt
    27721 tcaattactg ataatgcttc ttccctcgta ctatagcttc cgatgaccgt taaatttttc
    27781 tcttccatgt aaattcctcc tagcaaatag atttatgatt ggtatattgt tacttataa
//
LOCUS       DADQCX010000034        27391 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.034, whole genome shotgun sequence.
ACCESSION   DADQCX010000034 DADQCX010000000
VERSION     DADQCX010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.034"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2058)
                     /gene="cadA"
                     /locus_tag="J8R83_001321"
     CDS             complement(<1..2058)
                     /gene="cadA"
                     /locus_tag="J8R83_001321"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAZ9574456.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRS"
     gene            complement(2200..2379)
                     /locus_tag="J8R83_001322"
                     /pseudo
     CDS             complement(2200..2379)
                     /locus_tag="J8R83_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(2582..2941)
                     /locus_tag="J8R83_001323"
     CDS             complement(2582..2941)
                     /locus_tag="J8R83_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAZ9574457.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(2971..3312)
                     /locus_tag="J8R83_001324"
     CDS             complement(2971..3312)
                     /locus_tag="J8R83_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574458.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(3309..3983)
                     /locus_tag="J8R83_001325"
     CDS             complement(3309..3983)
                     /locus_tag="J8R83_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9574459.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(5160..6458)
                     /gene="asnS"
                     /locus_tag="J8R83_001326"
     CDS             complement(5160..6458)
                     /gene="asnS"
                     /locus_tag="J8R83_001326"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAZ9574460.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(6498..7688)
                     /locus_tag="J8R83_001327"
     CDS             complement(6498..7688)
                     /locus_tag="J8R83_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9574461.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFLKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(7709..8236)
                     /locus_tag="J8R83_001328"
     CDS             complement(7709..8236)
                     /locus_tag="J8R83_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9574462.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(8283..11072)
                     /locus_tag="J8R83_001329"
     CDS             complement(8283..11072)
                     /locus_tag="J8R83_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9574463.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEMELFIYVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMTTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(11219..11419)
                     /locus_tag="J8R83_001330"
     CDS             complement(11219..11419)
                     /locus_tag="J8R83_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9574464.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(11871..12191)
                     /locus_tag="J8R83_001331"
     CDS             complement(11871..12191)
                     /locus_tag="J8R83_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574465.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(12575..13693)
                     /locus_tag="J8R83_001332"
     CDS             complement(12575..13693)
                     /locus_tag="J8R83_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574466.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            14164..15471
                     /locus_tag="J8R83_001333"
     CDS             14164..15471
                     /locus_tag="J8R83_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAZ9574467.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            15590..16789
                     /locus_tag="J8R83_001334"
     CDS             15590..16789
                     /locus_tag="J8R83_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAZ9574468.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(16816..18084)
                     /locus_tag="J8R83_001335"
     CDS             complement(16816..18084)
                     /locus_tag="J8R83_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAZ9574469.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(18247..18894)
                     /locus_tag="J8R83_001336"
     CDS             complement(18247..18894)
                     /locus_tag="J8R83_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAZ9574470.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALATEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMIYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(19302..19805)
                     /locus_tag="J8R83_001337"
     CDS             complement(19302..19805)
                     /locus_tag="J8R83_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9574471.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(19928..20692)
                     /locus_tag="J8R83_001338"
     CDS             complement(19928..20692)
                     /locus_tag="J8R83_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAZ9574472.1"
                     /translation="MKEIQSAKNPKIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            20800..21075
                     /locus_tag="J8R83_001339"
     CDS             20800..21075
                     /locus_tag="J8R83_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAZ9574473.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            21513..22463
                     /gene="yidC"
                     /locus_tag="J8R83_001340"
     CDS             21513..22463
                     /gene="yidC"
                     /locus_tag="J8R83_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAZ9574474.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYHENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(22642..23616)
                     /gene="lacD"
                     /locus_tag="J8R83_001341"
     CDS             complement(22642..23616)
                     /gene="lacD"
                     /locus_tag="J8R83_001341"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAZ9574475.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPECGLPAAALREKECGLLLAYEKTGYDTKMPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECDAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLKETATPVYVDR"
     gene            complement(23613..24071)
                     /locus_tag="J8R83_001342"
     CDS             complement(23613..24071)
                     /locus_tag="J8R83_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAZ9574476.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYRK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(24068..25531)
                     /locus_tag="J8R83_001343"
     CDS             complement(24068..25531)
                     /locus_tag="J8R83_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9574477.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTILADNEAVDTLESETISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     SGGTGFLVGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVVFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPINKAAYVTGTALLAQGN
                     TTFMAGVSVACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEEGRAGGLS"
     gene            complement(25513..26463)
                     /gene="pfkB"
                     /locus_tag="J8R83_001344"
     CDS             complement(25513..26463)
                     /gene="pfkB"
                     /locus_tag="J8R83_001344"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAZ9574478.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQKKQIQTEFIEVPGMTRINVFTQVNQTREE
                     YKLVNQGPEIPQAAVHNFLNQIRALQAEDYLCVSGSLPRGMSPKVLVEISRICQEKEI
                     HLIIDSSDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENV
                     LLSLGEKGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLVGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            26606..27354
                     /locus_tag="J8R83_001345"
                     /pseudo
     CDS             26606..27354
                     /locus_tag="J8R83_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
BASE COUNT         7929 a         5883 c         4805 g         8774 t
ORIGIN      
        1 gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa atactgcatc
       61 tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta tcccaatagc
      121 aaagacaatg ttctgtttga cgattttcaa tgttttcttt gctaaatgga ttgcttctgc
      181 aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg cagcatcgct
      241 tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg catcgttgat
      301 tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct ctaaccgctg
      361 cactttatct tctggaagca attcgctata tatcttgtcc acgcctactt gcttcccgat
      421 atgatcagca atttttttcg aatcgcccgt caacatgact gtgttcttca caccagcctt
      481 ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa taacaagata
      541 accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt gacttgaagg
      601 aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt gtttgccatc
      661 aacttcagct aagatccctt cacctgcaaa ttcttggata ttagctgttg gtaaaagcgg
      721 acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact gttctgcact
      781 cgcaacatat tgcatgaata tctttggatc gatttttgta tcgatcgtct ggatcgaaaa
      841 gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcagttt gtgcaagcaa
      901 ctccaagtaa tttgaacctt ttactaatac accgatttta cttgctcctc cgataccgcc
      961 aaagaaacta aggggtacgg agatcactaa tgcacatgga catgagatca ctaaaaatgt
     1021 caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg gaggtaaaac
     1081 agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga atttagtaat
     1141 gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta ataatttgct
     1201 gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat ttttattgat
     1261 aaatccactt aatactgttt caccaacata tacagattta gggactgatt ctcctgtaag
     1321 tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg gtacacgttc
     1381 accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca cggtcatcaa
     1441 tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt cgcgaatcga
     1501 ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat aaaatagcat
     1561 cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag caacagacat
     1621 aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct tcttcactac
     1681 atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg gttcattaaa
     1741 atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga acagcgtatt
     1801 tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg ttactttgac
     1861 atctggttct aattccttca ctactttttt tatttcttgt tcaatcgtag ccaaatgatc
     1921 ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt ccttgactcc
     1981 attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat ctaaaccttc
     2041 taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaata tctcttcata
     2101 actaattata aatgaacggt tattcatatg tcaaggtatc cgaaagaaaa aatgaaaaac
     2161 atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct ttttcttttc
     2221 gatcattgcc actgctctta tccaacccgc acttgccttc ttgatcttga caggatagca
     2281 actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt cgataggaca
     2341 atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc cactacgctt
     2401 tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata aacagtaacc
     2461 ccatataaat aaaagacgta aaagtcacat ggaagaactt atacaggaga acgcatagag
     2521 tcaggtgaaa tacatgtatc ccacctgact ctatgcttta tctaaccttt attattctct
     2581 tttatacaat ttctgcaccg aatggcatca acgccaatcg agcaagtttg aaagattgct
     2641 tggcaaaagg tatccctatg atcgtgatac atagaaggat gccgctgacg acatgtgcga
     2701 gagcaattgg taggcctgaa acgatcagcc agatgatatt aacaatcaat gacatgccag
     2761 actggtgata aattacttct ttgccaaaag gcgcaaaaga aagggaggcg atcttaaaac
     2821 attgcatacc gattgggata cctatgatcg tgatacacca aagtatcccc gctgctaacc
     2881 agctaagacc accgattagt ccgccgaata taaaccagat gacatttcct aaacaactca
     2941 ttgtatttct ccttctatta ctgtttttga ttaaaactgg gcaaaaaatg attttattct
     3001 tcttttttta gcttccagta tcaaatattc tgcaaatttt ttttggattt cttccgtatt
     3061 ttcttttgtt actaatgtgt gttggattag ttttcctgat ggtcgctgat ccaatcgttc
     3121 ttctgactgt tgcacgtccg cttgcgcaaa tccgataatc cgtttttctt ttgttacagc
     3181 aacgagcaat agtttattct tatcatttag gtcagctgcc gtttttgctt ttacgaatga
     3241 ttctggatga tcagtaatca gctgattgat ttgaggtaga tcttctttta ctgcccaccg
     3301 tatttccatc atttctcact tttctttcgc tcatttttat ctccactaaa aaaatcgact
     3361 gcggcaattg catctatcca gctttgtgca atgatctcat gtccgccaat cgttgggtgg
     3421 accccatctt ctcttgtata tttcgaaaaa ccataaacaa tccctaaagc attgaatata
     3481 ccatctaaag gaaccagcaa tgcgccatat tccttagcaa gtttacgaac aatttggatt
     3541 ttagggtcta agtctttacg ccagccatga cggtcgtcgg ttataggaag tacaaacggc
     3601 tccatcaaga tgatgttgca gattcccact gtttgaagtt catttagtaa ttttcgataa
     3661 acggattcaa attgctgagc agatttctca gttccgaata tagcctgatc gctagtatta
     3721 tgccaggtat cattgattcc gatcaaaatc gatacatagt caggttgtaa agctaaacaa
     3781 tcttcttgcc agcgtacttg cagatctgca attttgtctc ctcctatccc acggttcatg
     3841 cattcaaatt ccatcgttgg atattgggag attagttttc cggcaatcaa aagtggataa
     3901 cctttaccta gatcagttgc ttctgctcgg tctcttcctg cgtctgtaat gctatcaccg
     3961 ataaataata tacgtttttt catttgtcaa aaactccttt ttgaataaaa cgatgatttt
     4021 cttccttata ttatcccata agccctatca agacgaaaga gaaaatatat gtataaaaaa
     4081 tgacaccagc ctagtccctt caaacaattg aatgaacgct catcaagtgt ctagtttttt
     4141 atgctatttt tttcttaacg tgccggattc cccttgattc cttcgttgtt tggtccagag
     4201 agatcgatca cacctaagct tccgtcaatc agaccactga tgacgccatc agaacatata
     4261 tttataggct catctaagac ttctagtaaa tgtcccttta ctaatatctc ttctagattg
     4321 cttgggatag attggtcata actttatctg gtccgatgat ttcaagggtg aattgaactt
     4381 acatatggat tattgcatgc tgaaaatacg gacctactcc atcttcgaat gttactatta
     4441 gtttgttttc aggtgctaga tgctgcttta tttcaacagc agaagcatca tcaaatcaga
     4501 tttccatttg aattaccttc tttgtaaatg tttgattgat tgcgatttcg ttatagaacc
     4561 ttgtgaatca aatagcaatt tcttttgctt tcttctcttg tctgctggaa acttccttta
     4621 tcccgtattt taaaaaaaga actgcgagag ttcgcagttc ttttttagaa taaacggtgc
     4681 tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa aactgttttt
     4741 tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt gatataaacg
     4801 gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg agaagctatt
     4861 tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc tcttccttaa
     4921 acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa tgtggaaagc
     4981 catttccaca aaatttttct taatactcga aactaaacag ctttttcaca acctctccac
     5041 taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca aaaacatgaa
     5101 cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt catcacctct
     5161 tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgcac atggtcgata
     5221 ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg cggaacagaa
     5281 ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc gtgattacgg
     5341 atttgttcta gcaagaaatc atagtccgtt gcccgttcgc ttccgccaat aatttcaccg
     5401 taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt tggatgtggt
     5461 ttcatgtaga atggcttgat agcttttgga tagtttagga taaagacagg ctgttcgaat
     5521 gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc gatgtcatca
     5581 aatccatttt tcttcagtaa ttcgatcgca tcatcataag taatacgagg gaatggcaat
     5641 tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc gtattcgcaa
     5701 tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc taaactttct
     5761 tcttgatgag tgaaagccat ttctggttcg atcatccaga attcaatcaa atgacgtcgt
     5821 gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc gaaagccata
     5881 gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg atcaaagtaa
     5941 tttgtttcga atagatccgt agtgccttct ggtgcggaac cagtcaagat cggcggatcg
     6001 attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat ttcatttctg
     6061 atctgcataa tcgcatgttg tcttgaagaa cgtagccata aatgacgatg atccatcaag
     6121 aagtctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct taccacttcc
     6181 acatttgtaa ttccgatttc ataaccaaat tttgaacggc tgtcttcacg gatttctcca
     6241 gttactaaca cggatgtttc ttggtgcaga tttttagctg tttggaaaac ttcttccggc
     6301 acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa ttgtaaaaat
     6361 gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac tgtttctccc
     6421 acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc ttttatattc
     6481 cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt gattctgcgt
     6541 accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt ttctggtgcc
     6601 ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc ttctacccat
     6661 tgtgtgacat tttcatattt acacatgcgt agcgtttctt ttacattagg aaaaagataa
     6721 aaagctcctt gtggcttttc aagagaaaca cccggcagtt ctgccacaag cggatataac
     6781 gtattcaggc gttcttcaaa ggcgttccgc atttcttcca ctgtatcttg ctcgcctttc
     6841 aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga ttgggaagca
     6901 acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat gcgccagcct
     6961 gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt gattgcttct
     7021 gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc ataaatatca
     7081 tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg cagttcattc
     7141 ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc ttttgttttt
     7201 tctgaacgtg cttgttctag ctgctcaaca gtaactttcc agctattgga ttcttctcct
     7261 ttcaaaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact gacccagtaa
     7321 ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag ggtatacaaa
     7381 gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag tccatagttt
     7441 ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt tggtgtataa
     7501 tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt ttctggtgtc
     7561 gcaaaatccg gttctcccac agtcaaactc agcacatctc tgcctttggc ttttaatgcc
     7621 ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt tctttttgat
     7681 aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg acttcatctc
     7741 cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt cctactactt
     7801 cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg atttcaggat
     7861 gggccgcagc aattgtctgt tttgcttcat tttcagtcag tccctttgtt tgatccaata
     7921 cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct ttatcatttg
     7981 tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga tcggcttcct
     8041 caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc accgccggac
     8101 gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa aatacgatca
     8161 agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc aagggtcgtc
     8221 gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa aagacagctc
     8281 ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata gatttcctcc
     8341 atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg tgcaccatat
     8401 tttgcagtaa ctagtcttcg atccaaaata agcaatacgc cacgatctgt ctccgtcctt
     8461 atcaagcgtc ctaatgcttg gcgtaacttc aaagctgctt taggtacgga ttcctggtaa
     8521 aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat cgggcgaagc
     8581 ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc aggcaaatct
     8641 acaccttccc aaaaactgtc agcgccaaac aatacgcttt tttctgacaa aatgaagcgt
     8701 ttcaaaagct tctcccggct tccgccaaac ccttgagcta gtatttctcg tcctttttct
     8761 agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga agtgaataac
     8821 acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc taaataatcg
     8881 atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac atagatcctt
     8941 gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc ttcaatgcca
     9001 agccgcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc aatataaaga
     9061 atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg aaaatcatgg
     9121 agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat caaatgatct
     9181 cgccagtctt ccagccattg atccatcagc aagtactgct tgtctaattg atcaaataag
     9241 ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg gataatctca
     9301 aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag ctgcaggtga
     9361 tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt cgtcatgact
     9421 tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa tccttctgcc
     9481 atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga taaccagcgt
     9541 aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg atttggttct
     9601 tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc atttactttt
     9661 tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact agctggaagc
     9721 aatggttctt ttcgctgtgt ttcttgtatt aaaaacgcat gattgacaat caaaaaatta
     9781 ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa tgactgattt
     9841 cttgctaaaa atccagtgcc tctgtgcgcg atatctgcaa agaatgaatg gttcaaattt
     9901 gttaaatgta attcatccaa atcaccggtc ttcgtttgcg tcagccaaac taagaccgcc
     9961 atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc tttaaaacgc
    10021 tgtaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg ctgatctagc
    10081 aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac tagcgaaacg
    10141 gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag cagataaccg
    10201 attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc atcttttgtg
    10261 aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat cagtgtttta
    10321 ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc ataatggacg
    10381 tatatgaata gttccatttc ttttttctgc aaagctagcc catcgacgat ttctaatgag
    10441 ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat gaaacgactc
    10501 gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat gattggcaat
    10561 tttctcatcc gttcttcgat cagcaaaaga agttgacccg tcacttcggc atcactatct
    10621 gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc taagcgaaag
    10681 cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc tggtatcttc
    10741 aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc aaaataaata
    10801 ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc gacatcttcg
    10861 aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg gatttgtttt
    10921 gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg acctgattca
    10981 atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc agtcgtttcg
    11041 atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc tgcctctaat
    11101 gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt ttaaagaaaa
    11161 tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta taggttaatt
    11221 aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca tcgaaagtta
    11281 ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag aaatgaacga
    11341 atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag ttaaaccatt
    11401 ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata ttttgcaatt
    11461 acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca gattaccgaa
    11521 caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt tttcgacttt
    11581 ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac tttttttaaa
    11641 ataaacgaca tattgttcag ttggtgtttt tttgctctga tgttcttctt taaactaaaa
    11701 aaattattct ttctgactac ttatcggttc tgtttcaacg gtcgaggctg gggaagattc
    11761 tttagtaggt ctgatgttct catggtattt ctgatagcct atgacagtta ccagaagaac
    11821 aaggcaaacc aatacgatca acgagattag tttttctttt ttgctcatat ctatacctca
    11881 taaataacag gatgatgtcc atcatatttc tgagtatgag taaaagcaaa agctgcagct
    11941 gtagaatgta agaaatgcca gcaactttca taatcacagg tcggacagta ccaaaagtaa
    12001 ccaaatcttg gctgcaaaga ccgttcttct gtttcaggaa tcgcagaatc aagatctgtt
    12061 gtctgtacat aaacattttt gtacagacgt gtgcctgtaa taggagaccg ctgtgtttct
    12121 tcagcaaaaa ctggctgact tgttaaactt agggatagaa acagcaaaca ccataacagt
    12181 ctttttttca taaagacctc cttatcgata agtttttccc aattaaaatc atatctcaag
    12241 aacgcccgtt attcacattt tgttcataaa tgatgttttt tgtatcataa tcgtcaaaaa
    12301 gaggtcgtga ccacgtcaca acctcttttt taaacggtgt tccagaagta gcttcttcgg
    12361 aaataagtcg aaatttcaca aaaatttgag aaataatttt tgtcaatctc ttcttatttc
    12421 ttgaagctga ccacttctgt cacaacctct tccttaaacg gtgttcaaaa gcttgcatct
    12481 gcggtattag ctcaaaaaac ggaaaaatat gtgaaactat ttttccgttt gtttctctaa
    12541 tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc gctgtcagac
    12601 tcttttcatc tggcgcatct ttttgatcca aaataaacac tttcccgcca ttaatgatca
    12661 catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca ggatcttcac
    12721 cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt ccttctttcg
    12781 cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt ttattgtatt
    12841 cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct tcgatatctc
    12901 taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa tagggatttt
    12961 tagcaatttt tttgaacatc gtctgatttt ctggtaatgc aaataaataa atcggccatt
    13021 gttcaggatt ttcgaaagaa tccttcaagt acgtatcaac agcttggtaa tagttgaccc
    13081 aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact ccatctcggg
    13141 ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca gatcccaatg
    13201 cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact tgtttgttgc
    13261 tgacctcata caatttcatg gagtcgcggt tcaatcccaa taaataataa gaatagttga
    13321 actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag tattgatcgt
    13381 ctaccgggat actcaaacga tggatatagg tctggtcagc agttataatg accgctacac
    13441 tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt ttttcttgga
    13501 acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct tctttcgcaa
    13561 aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc gtattcagca
    13621 tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgtcaat aattctttat
    13681 ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc tatctaaagt
    13741 ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa acggtttcta
    13801 cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat tatttagccc
    13861 cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata aaagaggtgg
    13921 atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta tttgctttca
    13981 gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta cgtaaaaacg
    14041 accgctaaac ttccataacg cgcgttctta tcctaaagtt ttttcagaaa cattgaaact
    14101 ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac aaggagatcg
    14161 gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat tctttgcctt
    14221 gcttcttttc taccagctgt tgctgtgcaa gctgaagata cgttcaaagt aaatgcaaaa
    14281 gcagcttttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga tggagaaaaa
    14341 accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct tgatcaagta
    14401 aaagaaggaa aactgtcatg ggatgataaa gtttcgattt cagattatgc agaaaatttg
    14461 agtatcaccc cagatttatc gaatgttcct ttgcataaag aaaacaccta cactgtcaaa
    14521 gaattattcg actctgcaat catccagtca gccaatgctt caatggtggc cttggcagaa
    14581 aaaatctctg gcagcgaagc taaattcact gaacgaatga aagaacaatt gaaagattgg
    14641 ggaatcaaag atgcaacaat cgttaatgca tcaggattga acaactctta tcttggcgaa
    14701 aaccgaccag aaggcactgg agaaaacgac gaaaatcaaa tgtctgctca agatgtggcc
    14761 atcgttgccc gccatttgat cttggatttc ccagaaatac tggatgtatc aagtactacg
    14821 acccaaatgt ttggcgaaaa tacgcaatca ccagtggaaa tggtcaactg gaactggatg
    14881 ctcccaggat tcgttaatta caaggaaggc gtggacggat taaaaactgg tacgactgag
    14941 cttgcaggtg cttgtttcgt tggtacgatc actaaaaacg atcaacggat catcactgtc
    15001 gtattgaatg cggacggcca tgcggaaaac ccgagtgccc gcttcaatga aacagaccgt
    15061 ttgatggact actgctatga caattggtca gaaaaagagc taggaaaagc taacgcaagt
    15121 attcctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt tcctgttgtg
    15181 cttaaaagcc ctgtaaaagt atgggtacga aacgatatgg atactggcaa attaacgatc
    15241 acgccaacac ttgacaagaa gcaagtcact gacaatgaga tccaagcacc tatggataaa
    15301 ggtacaaaaa tcggtaccgc tacgatcacc ttggcagacg ataaattagg ctatttagaa
    15361 gacaacaatg caccttcaac agagatcatt acggataaaa cagtggaaaa agcgaatata
    15421 ttcgtgattg gctggcgacg cgtcgcagaa tttttcggca acttgtttta attgaacaat
    15481 aagaaaaaca tctttccatc ggaaagatgt ttttttgctt tttctagttt aaataacagc
    15541 ttttttcatc tattttcgtt atactgtata agaaaaagga gttgaattta tgaatctaac
    15601 cagagatctg atctttttag ttctctatct tattggggta ttctctatcg tttattggcg
    15661 aaaacagaag aaggatcctt ccttgttctt ttacggcagt acgtggacat ttacggtaat
    15721 cttaacttat tttgtcgtgt tggaaatttt ttattcgacc ttttattttt tgattccatt
    15781 gttgttcttt agtatctttg ctttttctta tttcacagaa aaacgaaggc tgctgaatgg
    15841 tcttttattc aatgttttcc tcatcagttt cggcatctac ttgtttgtct tgctgtatga
    15901 aacgcaaaat attttccttg gcggactgat cgccttgatc acgattccat tgctacttgt
    15961 ccttttattt ggtatttatg gattgattgt ttttcttttt tggaacgggg tcacagtttt
    16021 acgtagagaa tcgcattcat tagctaatct tttaacgttg atactagcca tttttcttac
    16081 actgtttctt gtttttgact ttttcttgtt aaaatatttg ccgcaatgga taaatgcttt
    16141 gtttttctgc gttcccctga tcttgatcta tctatttatc gtattctaca actttttgac
    16201 tgtctcattc ttgtatcagt tcaaccggcc tcgatacaat caagacttca tcgttgtgtt
    16261 aggcgctggg ttgatcaatg gagaaacagt ttctcctctt ctagccaagc gaatcaataa
    16321 ggcaattgct ttttatcggg ctcaaagccg tgctacatta aatccgccca tcttattgat
    16381 gtctggcggg caaggagcag acgaaaaagt accagaggcc attgcgatga aacaatatgc
    16441 catggaacaa ggaatccctg aaagagacat tcttgtcgaa accaattcga caaccacttt
    16501 ggagaacatg ctctattcaa aggaaatcat ggatcagcaa atgaaagggc cataccgcgc
    16561 gatctttagt tccaacaatt accacatttt tagagccggt ctttatgcgt ggcaagccaa
    16621 attgaaagca aatggtattg gtgcaaaaac agctttctac tacttgccta atgcgttttt
    16681 aagagaatac atcgccatct tgatgatgaa caaaaaaaga catatgatca tttgcggatt
    16741 gcttttcgca ggctccgcat tcttatcgct gattacttta cttttctaaa aaaacaaggt
    16801 gtgacaaaac atatgtcaca ccttgttttt ttctttcatt ctcttaacta ttggcaaaaa
    16861 gagtatccct tttttgaccg ctacttgctg agcagaataa ataccgctgt tgcctgaaca
    16921 cataaagctg atcaagcaga tcataaagaa gtatactgcc gcttgtgaac cgaacaattc
    16981 gatccccatc acaaagcagg caatcggtgt atttgtcgca ccagaaaata ctccgataaa
    17041 gcccaatcct gcaagaaaag gaacagaaac atggagcaaa ggcgctagtg ctgcaccaag
    17101 cgttgcacca atttcaaaca atggtgtcac ttctccccct tgatatcccg cgcctaaaga
    17161 caaaactgtg aagaataact tcccaataaa atcatagaca tgtgcctgtc cattaaatga
    17221 ttcttgaagt aacggaagac tcaatccgag ataacgttgt gtttgcaaaa tcaatgctgc
    17281 tgccacaact acagctccac ctatcgtatt tcgccaaaca ggatgaggaa tccattgtgc
    17341 atatcgcgct tttaaaaaga cgatcgaacg gctgaatacc caaccaatca aaccaaaagc
    17401 aatcccagca acaaaaactt tgaagaacag caacatactc cattcaggaa tcacacccat
    17461 ttggtaatgt agatgagaaa caccatagct ttctgtcatg aaatttgcaa acagtgcagc
    17521 aaagaagcta gggaagatcg cttctgttcg gactttcccg attgccaaca cttctaatcc
    17581 aaataatgtt ccagctaaag gtgtgccaaa tacagaacta aaacccgcac tgattccact
    17641 gataatcaag atttcccgtt ctgatttatc caatcggaac aaacgtgctg tattatctgc
    17701 taacgctccc cccatttgga ctgctgttcc ttcacggcca acagatcccc caaataaatg
    17761 ggtagttatg gttccaaaca gtgtaagtgg aataagtcgc aacgggattt tttcttctcc
    17821 accatttcct tgatcgatca ctaagttgtt tccacgacta gaaagaccgc cgtgatacgc
    17881 atagagataa gcaaaaagcg caccactaac tggtagtaga taaaggagcc aaggatgtga
    17941 tagtcggata tctgtcacaa ctgtcaggct atttaagaaa aaagcagaca agctccccat
    18001 gaatataccg agaatcgctg tgatcaccag ccacttcagc atgtacacta aaatgcgtac
    18061 tggactcggt aattgttttt ccataaaaaa ttcctcctca ataaaaaaac gcctactaaa
    18121 gaaaggggct gtccccagac tttagtaggc gtcattagct atctttcgtt agcatttaaa
    18181 ggcgaacacc atcacctatt cacttccatt aaaagatagc atatttttct gtaaaaaaca
    18241 ataaaattat cgttctttct ttacacgttc agcaaattca tagaaaggag ccaatttcgt
    18301 taactgttga ttacattggt cactatcatg acaaatataa ttcccctttt tcgtatacgt
    18361 gccatcagaa cctgctttcg ttgtagaaag aaaaagcgaa acattcgatg ttttctgaca
    18421 gattgcacag attcccttat ttatcgttgg tgataaagta ccactaatcc cttttaattt
    18481 ttcatcttcg taatagatca tgaatttttt ctgcgtacct ggatcattcc agccgatgta
    18541 cgtatgttct tgcaagtcga tttcattcca agctggttgt ttgagttttt tcacttttcg
    18601 gaataatttc tcgatttgtg gtttgctagg ctgcataaac ggctgaacga tttgcttcag
    18661 ctcctccaat gctcgttctg cttgcgcttt tgtcagtttt acgtctaaaa ctgtcgttaa
    18721 aaatgtatcg atttctggca gttcgtgttc taatatgtct cgaatctttt cagttgctag
    18781 tgcctgaact gtttgtaccg tttttggatc attgacagat gagtacgcat ttaataactg
    18841 ttctacttct ctttttataa aaaaatattg gtatggtttt attgtttgtt ccatgatttt
    18901 aaagtccttt cttctaacca aagtgcatac tttgtagaaa aaagtgatct tctgcaaagt
    18961 atgtgttacc tgaagatccc ggactctttt aaataagata cgttttgcat cttatcatca
    19021 ccccctttaa tgcttattct tctatgtaca tgattcattc gataaataaa agtaaaccgt
    19081 atcttgaaca gatagtcaac tgcaaacaga aaaaaggact gtgacaaaag tcgtgtcaaa
    19141 gtcccttgtt tcgaatgaat ggtgttcaaa agcttgcatc tgcggtaata agccgaaact
    19201 tcacaaaaat ttgagaagta attttcgtaa attccttctt atttcttgaa gctgaccact
    19261 tctgtcacaa cctcaatatg gtctattatt ggttttacct gttaaatcga ggattctttc
    19321 ccaaagtaac gttgccatct cttacgcata cttgcagaca tgggctgagc cgcttctttg
    19381 actgcgcagt atttgtccac gaatgtcaca atatatcctt ctttatactt aggcggtgcg
    19441 atcgttgcac cccacatgtg cttcaaaatg atatctcgct caagatccga caaatcggtg
    19501 attttttctg cattctttac agcaattctt ggatggatat acgcatgtgt cccctcgtca
    19561 aatttcgtcg tacgccaatc atagtagaac agatcatgca aaagtccagc acgcgctgtt
    19621 gctttagcat tgccacccca tttttttgcg agcagataac tatagtaaga aacactgatg
    19681 gaatgctcca aacgagtgga atgaacatgc tgtgtgtaat tcgctaattt tttcactgct
    19741 tctgtttcta aaagatcttg tacataagac atatattctt cgtcttcacg ccatttttct
    19801 gtcataatta tcgatctgcc acctttttga atttcatttt cttctgaaat tgatctaagt
    19861 ataccaccag tgttcggatt attctagtcg ctctagataa aatagctaaa gcttaatagt
    19921 tccttaatca taaagaaaaa tgataaagaa cgatccctgc tgcgactccg acattcaatg
    19981 attccgcatt tcctttcatt gggatatata cgttctgatc agtcaaagac aagatttcct
    20041 gacttactcc ctgaccttcg tttcccatga ttatagcgaa atcctctgtt ttttctactt
    20101 tgtctaatgc atgtgcttct tcatttaatt ctgtaccgta caccgtaaac cctttgcctt
    20161 tcattacagg gatcacttct gccaaatctt tttgtaacac aggcaaatga taattgcttc
    20221 cctgcatgct tcgcagcacc tttgtactat aaatatctgc cgttccttta cctaataaaa
    20281 caccagccat accaaacgca tctgccgtac ggatcatcgt tcccacattt ccaggatcct
    20341 gtacattatc tagtaaaagc cagcctcctg aaaaatctgg cgtatcttca gatgttaacg
    20401 tcatcaccgc taagatccct tgcggtgtag gtagatctga catagcggtc atgacctcat
    20461 ctgaaactag aaaagtagaa atctctttgt ttacagccag ccagtctccc cattctttca
    20521 tacctctctg tgtcacaaaa agttctttta tttctgcatc agacgacgca gcttcttcga
    20581 tcagatggaa cccttccaaa agatattctg ccttttcttc tctgtatttc tttttatgta
    20641 gcttttttaa ttctttgatt tttggatttt ttgctgattg gatctctttc acattccttc
    20701 acctcacctg attatatcat ggaataggtg cttgagcttg tttcatccta aaaaaatcgg
    20761 tatcattgat ttataaaaca ggaaagaaag gtgacgaaca tgcgcaaagt taaaatgaat
    20821 gtccaaggac gtgtccaggg cgtgggattt cgctatatga ccaagatggt tgctgatcag
    20881 ttaggcgtga ccggaacggt aaaaaacgaa gacgacggct cagtcacaat cgaagcaatc
    20941 ggaaatgacg acatcatcca aaaatttatc gaagaagtca agaagtctcc gagcccaagt
    21001 ggacgagtgc agtatgtgga tgtccaagaa gatccgatga ttgaggaacg aaagaaattt
    21061 gatgtggtgg gataaggttg tgaaaaggtc gcttagtttt gagtattaag gaaaattttg
    21121 tgaaaatggc tttccacatt tttgcataaa tttgacttaa taccgagaaa ctgacttttg
    21181 aacaccgtcg atcaggttgt ttttgaggcg ctttgcctca agtattaaag ataggtagta
    21241 aaaaagctga tctataactt gcaataaatt tgcttaaccc atattttcca gacagaacaa
    21301 aaaagttttt agttttttat ataagaaaga aacacttgga atcactcttt tctttccaag
    21361 tatttctttc ttgatttttt gtcttttttc aaaatttttc gctacgaaaa agaaagaata
    21421 tttatatgaa atttctatga agttgattga attccatgcg cttttttagt atagttaagt
    21481 ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac tggttattgg
    21541 gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg gattcaaacg
    21601 gaaaccctga cacttcagga atcgtttatc gagtactcgt ccatcctatg ggccaagcga
    21661 ttacatatct agttgagaat ttcaattggt cttacggctg ggcagttatt gcaatgactg
    21721 tgatcgttcg tatcatcatc ttgccactag gtatcagtca atcgaaaaaa acaatgatcc
    21781 aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcacaacaa aagctaaaag
    21841 ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa gtatatcacg
    21901 aaaacggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc caaatgccga
    21961 tcttctctgc cttgtatttt acggctcgct acacagaagg tatccgtgaa tcatcttttt
    22021 acggcatcga tctaggctca ccaagtatgg tgcttgtggc cattgcaggg gtcgcttatc
    22081 tgcttcaagg atatatttca acaatcggta ttcctgaaga acagaaaaag acgatgcgta
    22141 cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg ccagccggcg
    22201 ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc atcacaaacg
    22261 ttatgatgaa accacgcttg aaagcacaag tggcagaaga gttgaaacaa aacccgccaa
    22321 aacaagtcgt cactccaaga aaagacgtga cagaatcagc aaaaccagct gacaacaaac
    22381 aagcaacaaa acaaatcaaa caaccaaaaa acagtacaaa taacaaaggc cgcaacgcag
    22441 gaaagcagca gaagcggaag tagatagtaa ataagagtgt aataaaaatt cattaacagt
    22501 tttagcaatt aaaaatatcg accaagattt ttgaaaaaga aatctagtcg atatttttat
    22561 ttaagtgaat gtataatttg aatcatcgat tgatcgctat ctaattgcag cagcatcttt
    22621 ttatgaagaa acaacttttt cttatctatc aacgtagaca ggtgttgctg tttcttttaa
    22681 tagtgtactt aattccttaa tattttgttt tccttcttct aacatccaac tactcgcttt
    22741 ttcttcgcct tcggtaacaa aaggtgccac tcccttcgcc catgttgctc gcccacataa
    22801 gacaccattg aatgtcgaac ctgattgttt tgcaaaacgt aatgtatctt gaaataacgt
    22861 agcattgact cccgcactta aaaaaataaa cggttgttca gtcactttcg attgttcata
    22921 gaaatacgcg gatgcctctg cttgactata acaagtctct tgcccatatc cttccacaaa
    22981 tctcatattc actggcactt ctactttcaa tacatccact tgataacgtt cttttgaaaa
    23041 ttctcgcatg gcttcaataa ctttatgggg ttttactttt gcataggcaa gagaggacgg
    23101 atcgccaata gttgcatcat aagaaaggat ctctaaaaag aaaggtatgc cttctgcatc
    23161 gcattctgaa ccaatccgtt ctataactat ttgtttttgc acattaatct ctgctggttc
    23221 atccacgtca tagtacaata aaaatttaca agcatccgca ccagcttctt ttaacctttt
    23281 caccgaccaa atattcaata aatcaggtaa tcttcccggc attttcgtat catagccggt
    23341 tttttcataa gctagcagca agccacattc tttctctcta agcgctgctg caggcaggcc
    23401 gcattctgga tcaagtaaaa tagctgaggc atagggagtc aggtattgag aaaccatctg
    23461 tttaaattgg atgatgtctt ctgatgtagc ttctttatat tggttgatca ttttcttcaa
    23521 agcaccacgc tggtcgattg ctaacgcgct aataattcca gcttcatccg tcaatcgctt
    23581 caaacgttcc tgcttttcta tactcatctt cttcatagat cttcacctat ttctttagtt
    23641 aatattgtgg ctatttctgt ttttgatttt gcttttctca actgttctgt aacctctttt
    23701 cgcatcaatg atcgtgcaac gagagacaat aatttcaaat gagtcgttcc tgcttctgaa
    23761 tctggaataa ataacgcaaa aataaaatca actgactgtc tatctaaact gttccattca
    23821 attcctttgt tcagtgtgac gataatcata ctaggttcgt tgattgtttg agacttcgca
    23881 tgagggatag caaaacctga cattattcct gtagtacctt ctttttctct ttctagaagt
    23941 tttcgatata cttctttttc gtcatgagcg attcctaaac agaatgtttg ctttgctaaa
    24001 aacttaaatg cttcttcttg actatctaat ggctgttgta aaaaaatgtt ctcttcatga
    24061 atgattgtca tgataagcct cctgctcttc cttcttcgat aactgtacga tttgctgctt
    24121 tattatccat cttcttgtct ttatcagtta ctcttttctt ttggatcaaa cctagtatca
    24181 ctccaccaac gatcgaacca ataagaatcg ctgtaaccca ttggattttt cccgtcacta
    24241 caggtaacac taaaaaaccg ccatgtgggg ctggtacttg gacaccaaac agataggtca
    24301 agacagcagc aattgatgag cctaacatca tcgttggtaa tactcggatc gggtctttcg
    24361 cagcaaacgg aatagctccc tccgtaatat gagttgatcc taaaataaaa ttaaccaaac
    24421 ctgcattacg atcattagta tcaaaatatt taccaaacaa taaagttgca aaaccagtaa
    24481 tcaacggtgg tgcaatgcaa gctactgaca cgccagccat aaaagtcgtg tttccttgtg
    24541 ccaaaagagc tgtacctgtt acatatgccg ccttattaat cggtcctccc atatcaaacg
    24601 cacacatgca accaacaatc acgccaagaa caagtggatt cgaatgttca aatccagcta
    24661 aaaagctcat cattccttca tttatagcct tcattggacc cgccagcaaa gacatcacga
    24721 tgccgataaa cactacacca ataactggat ataagaagat tgccttcaag ccatctagtt
    24781 gtttaggtaa aattgtcagt agcttttgca aaaataagat aaaataacct gctaagaacc
    24841 cagctaaaat acctactaaa aatccagtac cgccactcat ggccacgatt ccaccaacaa
    24901 atccaacgac taaccctgga cgtttcgcga tcccttctgc aatataagct gctaaaactg
    24961 gaaccatcat ccccattgct gcatcgccaa ccgtttttaa catcgccgct gtagcattgt
    25021 attgtgcatg gtctggatca aaagaataga ttccccaaac ggcaaatgaa atagcaatca
    25081 atactccgcc agctaccacg aaaggcaaca tatgagagac gccattcatt aaatttttat
    25141 agatgctgcg accaaaatta gcaccactta tcgtttctga ttctaaagta tcaacagctt
    25201 cattatctgc taagatggtc ccttttcctg ccaatgcttc gtcaatcagc cgttgtgcat
    25261 ccttgattcc tgtactgaca gaaacatcaa tgactcgttt tcccgcaaat ctttctgaat
    25321 ggacatcttt gtctgcggca ataatgacag catctgcctg tttgatttct tcagccgtta
    25381 attcattctc gatcccaatt tgtccatggg tctccacttt gatcgtgatg cctttttttc
    25441 tagctgcttg ctctaatgcc tcttgcgcca tgtaggtgtg tgcaattcct gtcggacaac
    25501 cggttgctgc aattagttga tattttccca tctttcgaac ctctcttcct tgattttgat
    25561 ttgtttactt aattcctcca catccaaaaa atcagtcagt cctttacgaa aagcagtaga
    25621 gctgcctgct gctatgcttt tacgtaacgt ttcatcaagc ggtcgtcgat tcatgtatcc
    25681 tactaaaaaa gtgcctaaca tggcatcacc tgcacatgct gtattgacaa cttttccttt
    25741 tggcgagttt cctcgaatca ccctgtcttt cgtaaaaaga atcgctcctt tctcaccaag
    25801 ggataacaaa acattttctg cacctgactc taccagtcgt tgtccataaa caaagtaatc
    25861 ttcatctgta accatttttc gtccgaacca agaagaaagt tcttcctcat tcggtttcag
    25921 caaaaatggt cgatagggca aacaatccat gacctcttga tcactgctat caataatcaa
    25981 atgaatctcc ttttcctgac aaatccgact gatttccact aaaaccttcg gagacattcc
    26041 tcttggtaaa ctcccagaaa cacaaagata atcctctgct tgtaatgctc ttatttgatt
    26101 taaaaaatta tggacagctg cctgcggtat ttcaggtcct tgattcacta atttgtattc
    26161 ttctctcgtt tgattgactt gtgtaaatac attgatacgc gtcataccag gcacttcaat
    26221 aaactctgtt tggatttgtt tcttctgtaa atagtcttct atatattttc ctgtgaaacc
    26281 agcagaaaaa cctaatgccg tacttgggaa atctagcatc tttaatacta gtgacacatt
    26341 tactcctttt ccgtttgcct gaatgtcatc ctcctttgta cggtttacca taaaaggatg
    26401 catctcctct gtttcaataa atagatcaat tgccaaattc atcgtgcatg tgtagataga
    26461 cataaccaat gacctccttg aatctattat gaaatacgcg aaagagaaaa tgttttctta
    26521 atcgttccaa cacaaagaaa acctttacat ttataaacac atcgtgctat tttttaacta
    26581 acttttagtg aaagaaggaa agaatatgga tcacaaatta agtgaaacag aacagtacct
    26641 ctggaacttt atcgaacacc acatcctaga gatccctaac tactccatcg tgaaactaag
    26701 tgaacaagca aatgtctcaa cagccaccat tgtgcggaca atgaagaaaa aaggctatga
    26761 aggatttact tcgtttaagc accatctaaa agaaggagaa aacaagaaca tcaatttttc
    26821 tttttagata aagtagacaa aggtatccgt cgagccattc taaaaaatga acaagaagtg
    26881 gtacgtacga tcaatatgtt ggaaatcggg aacattgaag atgcaataca aagaatcaaa
    26941 tttactgacc gggtttttgt ctttgcccga ggattttcag aaatgattgg tcaagagatg
    27001 ctcgtaaaac ttcaattaac aggaaaaaat tgtcaaatgc atactgatcc agagattatc
    27061 aaaagcatca gtcggaaact aactaagaaa gacagcgtta tttttgtttc tttgaacggc
    27121 gagacaaaag aactcgtcac cgccgcaaag aactgctatg atgcagagat tggttcgatt
    27181 ctagttacag ccaatcattc ctctacactc aaagattatt gcgagataaa tctcgtaggt
    27241 ttcaaatcag aaggttctta tttccctgat tatgaagtac gttcacgctt gcctctccag
    27301 atcatcgcga gaatcctgct tgacgcctat gtattgcgta tgagggagaa ttgagaagca
    27361 gtttattatg gttggttaca gtttaaaaca t
//
LOCUS       DADQCX010000035        26352 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.035, whole genome shotgun sequence.
ACCESSION   DADQCX010000035 DADQCX010000000
VERSION     DADQCX010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.035"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(98..1228)
                     /locus_tag="J8R83_001346"
     CDS             complement(98..1228)
                     /locus_tag="J8R83_001346"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAZ9574479.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1877..3079)
                     /locus_tag="J8R83_001347"
     CDS             complement(1877..3079)
                     /locus_tag="J8R83_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9574480.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="J8R83_001348"
     CDS             complement(3139..3342)
                     /locus_tag="J8R83_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAZ9574481.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="J8R83_001349"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="J8R83_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4879..5691
                     /locus_tag="J8R83_001350"
     CDS             4879..5691
                     /locus_tag="J8R83_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9574482.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="J8R83_001351"
     CDS             complement(6715..6867)
                     /locus_tag="J8R83_001351"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574483.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="J8R83_001352"
     CDS             complement(7058..7936)
                     /locus_tag="J8R83_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9574484.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="J8R83_001353"
     CDS             complement(7975..9093)
                     /locus_tag="J8R83_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAZ9574485.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="J8R83_001354"
     CDS             complement(9090..11189)
                     /locus_tag="J8R83_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAZ9574486.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="J8R83_001355"
     CDS             complement(11240..12061)
                     /locus_tag="J8R83_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9574487.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="J8R83_001356"
     CDS             complement(12058..12867)
                     /locus_tag="J8R83_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574488.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="J8R83_001357"
     CDS             complement(12888..13382)
                     /locus_tag="J8R83_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9574489.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="J8R83_001358"
     CDS             complement(13394..13882)
                     /locus_tag="J8R83_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9574490.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="J8R83_001359"
     CDS             complement(13959..16655)
                     /locus_tag="J8R83_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9574491.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="J8R83_001360"
     CDS             complement(17083..18156)
                     /locus_tag="J8R83_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574492.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="J8R83_001361"
     CDS             complement(18153..18980)
                     /locus_tag="J8R83_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574493.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="J8R83_001362"
     CDS             complement(18981..19787)
                     /locus_tag="J8R83_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574494.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="J8R83_001363"
     CDS             complement(19799..20884)
                     /locus_tag="J8R83_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574495.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="J8R83_001364"
     CDS             complement(20901..21443)
                     /locus_tag="J8R83_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9574496.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="J8R83_001365"
     CDS             21701..22690
                     /locus_tag="J8R83_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAZ9574497.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="J8R83_001366"
     CDS             22687..23424
                     /locus_tag="J8R83_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAZ9574498.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="J8R83_001367"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="J8R83_001367"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAZ9574499.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="J8R83_001368"
     CDS             23988..24620
                     /locus_tag="J8R83_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9574500.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="J8R83_001369"
     CDS             24705..25352
                     /locus_tag="J8R83_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9574501.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="J8R83_001370"
     CDS             25357..26340
                     /locus_tag="J8R83_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAZ9574502.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
BASE COUNT         8060 a         5570 c         4465 g         8257 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 tcaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg at
//
LOCUS       DADQCX010000036        25281 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.036, whole genome shotgun sequence.
ACCESSION   DADQCX010000036 DADQCX010000000
VERSION     DADQCX010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.036"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(55..432)
                     /locus_tag="J8R83_001371"
     CDS             complement(55..432)
                     /locus_tag="J8R83_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574503.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            688..1416
                     /locus_tag="J8R83_001372"
     CDS             688..1416
                     /locus_tag="J8R83_001372"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAZ9574504.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1416..1670
                     /gene="purS"
                     /locus_tag="J8R83_001373"
     CDS             1416..1670
                     /gene="purS"
                     /locus_tag="J8R83_001373"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAZ9574505.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1672..2343
                     /gene="purQ"
                     /locus_tag="J8R83_001374"
     CDS             1672..2343
                     /gene="purQ"
                     /locus_tag="J8R83_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAZ9574506.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2344..4566
                     /gene="purL"
                     /locus_tag="J8R83_001375"
     CDS             2344..4566
                     /gene="purL"
                     /locus_tag="J8R83_001375"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAZ9574507.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4551..5990
                     /locus_tag="J8R83_001376"
     CDS             4551..5990
                     /locus_tag="J8R83_001376"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAZ9574508.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6022..7065
                     /locus_tag="J8R83_001377"
     CDS             6022..7065
                     /locus_tag="J8R83_001377"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAZ9574509.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7062..7640
                     /gene="purN"
                     /locus_tag="J8R83_001378"
     CDS             7062..7640
                     /gene="purN"
                     /locus_tag="J8R83_001378"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAZ9574510.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7637..9172
                     /gene="purH"
                     /locus_tag="J8R83_001379"
     CDS             7637..9172
                     /gene="purH"
                     /locus_tag="J8R83_001379"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAZ9574511.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9188..10462
                     /gene="purD"
                     /locus_tag="J8R83_001380"
     CDS             9188..10462
                     /gene="purD"
                     /locus_tag="J8R83_001380"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAZ9574512.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10584..11498
                     /locus_tag="J8R83_001381"
     CDS             10584..11498
                     /locus_tag="J8R83_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAZ9574513.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11631..13196)
                     /locus_tag="J8R83_001382"
     CDS             complement(11631..13196)
                     /locus_tag="J8R83_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9574514.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13189..14640)
                     /locus_tag="J8R83_001383"
     CDS             complement(13189..14640)
                     /locus_tag="J8R83_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9574515.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14654..15670)
                     /locus_tag="J8R83_001384"
     CDS             complement(14654..15670)
                     /locus_tag="J8R83_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574516.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15890..16978
                     /locus_tag="J8R83_001385"
     CDS             15890..16978
                     /locus_tag="J8R83_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574517.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17032..18558
                     /locus_tag="J8R83_001386"
     CDS             17032..18558
                     /locus_tag="J8R83_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574518.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18560..19765
                     /locus_tag="J8R83_001387"
     CDS             18560..19765
                     /locus_tag="J8R83_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574519.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20022..20999
                     /gene="guaC"
                     /locus_tag="J8R83_001388"
     CDS             20022..20999
                     /gene="guaC"
                     /locus_tag="J8R83_001388"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAZ9574520.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21263..22687
                     /locus_tag="J8R83_001389"
     CDS             21263..22687
                     /locus_tag="J8R83_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAZ9574521.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23148..24257
                     /gene="pdhA"
                     /locus_tag="J8R83_001390"
     CDS             23148..24257
                     /gene="pdhA"
                     /locus_tag="J8R83_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAZ9574522.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24260..25237
                     /locus_tag="J8R83_001391"
     CDS             24260..25237
                     /locus_tag="J8R83_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAZ9574523.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8178 a         4304 c         5684 g         7115 t
ORIGIN      
        1 tttaaaagcg gctacctctt taccgtgcct ctttacatac aaaaaataga ggaattaagc
       61 gtaaatggct tggctattat aactaaaatg ctggttatgg agatgttgca gcaagttttc
      121 gagaaaagcg tattccatct cttgtccatt gaataagatc tggatacgat aatgattttt
      181 gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg cctttgtgtt ctgtctgata
      241 aagaaaagtc cttttacggc attcagcaca gcgcttggtt gctcggcgga tttttcggaa
      301 tgtataaaaa ctagtatctt tattgcataa ataaacgtct ttgatcgaca gcaaatcatt
      361 atatagacag gaacgttctt cagctgttaa ttctgataaa aaaagctgac cttgttttat
      421 tgcatcttcc atcggcaagt gcctcctcga acccattaac caaattttta gttaattcta
      481 atataccatc attaagtata aatgtaaacg cttgttgatg gtataagatt ttcgtttctg
      541 ataaaacacg aacattaaaa gaatctaatg ccttaaatgt acatattttt gttgatttat
      601 aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca aaaaacgatg tatttgcttt
      661 taatgtaaat aaaaaggaga gacgtacatg gagaagaaag aacttttgta tgaaggaaaa
      721 gccaaaaaaa tatatcttac ttctgatgag aacttgattt ggatagaata tttagatcaa
      781 gcaactgcgt tgaatggcgc gaggaaagac cagataagtg gaaaaggaga attgaataat
      841 caaatcacaa gtgcaatttt ccgttatctg actcaaagag gaataaaaaa tcattttatt
      901 gaacaattgt ctaaaaccga acaattagca aaaaaagtac aaattatccc tctggaagtg
      961 gttatccgaa atattgcagc aggaagtttc tcaaaacgtc taggtgttcc cgaaggtaaa
     1021 gaattcatca aaccaatcat tgaattctac tataaggatg accagttgga tgatccattt
     1081 atcaatgaag agcatatcta tttcttacaa cttgcaaagc cggaagaaat cagtgagctg
     1141 aaagcccaag cgttggctat taatgaaatt ttgaccgaat tatttgctaa ggtcggtttg
     1201 gttttagtag atttcaagct agaatttggc cggtcgaatg gacaaatttt gcttgcggat
     1261 gaagtaacac cggatacttg ccgattatgg gatgaacgta cgaatgaaca tatggacaaa
     1321 gacgtttacc gcagagatct aggtgatttg atcccagtct atcaagaagt atataaccgt
     1381 ctatcggaac taactgaaga aaaggagcga gtatgatgta tttcgtaaaa gtatatgtaa
     1441 cctataaaga ttcagtgtta gatcctcaag gggaggcagt aaaaaaagca gtccatcgta
     1501 tgggatatga aacaatcgaa gatatccgaa taggaaaata ctttgagata caacttgctg
     1561 atgcagaaga accaatcgat acagtgattg aaacgatttg tgacaagctg cttgcaaatg
     1621 taaatatgga aacataccga tatgaaatca aaaaaatgga ggaagtataa catgaaattt
     1681 gcggtcatcg tttttccagg ttcaaattgt gacgcagata tgttatgggc agttcgcgag
     1741 atcatgggcg ctgatgccga atttgtacgg catgatgagt cctctttaga aggatttgat
     1801 ggggttttac tgccgggagg attctcctat ggtgactatt tgagatgcgg tgcgattgct
     1861 cggttttcta caatcatgga agaagtgatt cgttttgctg aagaagggaa accagtattc
     1921 ggtacatgca atggattcca gatattgaca gaagcaggac ttttgccagg tgtactgaga
     1981 cgaaatgagt ctttgcattt tatttgcaaa actgtaccat tgaaagtcaa ccccaagacg
     2041 gcctttactt cagagtatga agccgacgaa ataatctatc ttccagttgc tcatggggaa
     2101 ggaaattatt tctgtgacga agaaacactt caagaactaa aaaaaaataa tcagattgcc
     2161 tttacttata atgacaacat caacggcagc gtggaaaaca ttgcagggat tacgaacaaa
     2221 gcagggaatg tgttaggaat gatgcctcat ccagaacgtg cagtagaaga cttgctagga
     2281 tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa acttcggaaa ggtgaccgta
     2341 tagatgaaaa cattgaaaga accgacagct gaagagatca agaaaaaaag aatctatgcc
     2401 gaatggggat tgactgatga agaatatcga atgatcgaag aagatatctt aggaagaatg
     2461 cctaattata cggaaactgg actgttttct gttatgtgga gcgaacattg ttcctataaa
     2521 aattctaaac cggttctacg caaatttcct actagtggac ctcatgtgtt gcaaggccct
     2581 ggagaaggcg caggcatcgt cgacatcggt gatggactag cagttgtctt caaagcagaa
     2641 agtcacaatc atccttcagc cgtggagcct tatgaaggag ctgcgacagg agttggcgga
     2701 atcatcagag atattttcag catgggggct cgtccaattg cgttgctaga ttcattgagg
     2761 ttcggcgaat tagataatcc aagaacgaaa tatttactag aagaagtagt tgcaggtatc
     2821 ggcggatacg gcaattgtat cggcataccg actgtaggcg gcgaaattgc atttgatcct
     2881 tgttatgaag gaaacccatt agtcaatgca atgtgcgtag gtttgattga acacaaacat
     2941 atccagaaag ggcaagccgc tggcgtcggt aattcgatca tgtatgtagg tgcaaaaaca
     3001 ggtcgcgacg gtatccacgg agcaactttt gcctcagaag aatttaatca agaagaagaa
     3061 cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg aaaagctgct gcttgaagcg
     3121 tgtttggaat taatcttgca tcattcggat tctctaatag gtatacagga tatgggagca
     3181 gcaggacttg tttcatctag tgcggaaatg gcttcaaaag ctggctcagg acttatattg
     3241 acattagatg aagtcccaca aagagaaact gggatgacac cttatgaaat gatgttatcg
     3301 gaatcacaag aacggatgtt gatttgtgtt aaatcaggag aggaagaaaa aatccaagaa
     3361 ctatttcaga agtatgatct agatgcagtc actatcggta aagtaacaga cgacgggcaa
     3421 tatcggctat atcatcaagg agaagaagta gcaaatctgc cagtcgatgc attagctgaa
     3481 gatgcaccag tttatcataa agaaatgaaa gaaccagctc gaatcgtaga atttcagcag
     3541 ttagctcctt atcagccagt tatcgaagaa cctggacaag tattgcttga tctgctgcag
     3601 caaccgacga ttgcttcaaa acgttcaatc tacgaaactt atgattcaca agtacaaacc
     3661 aatacagttg tccgtccagg aagcgatgct gctgtgatga gggttagagg gacgaataaa
     3721 gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt atttggatcc aaaaatcgga
     3781 ggacaaatag cagtggcaga agctgctaga aatattattg ctagcggtgg taagcccttg
     3841 gcgatcaccg actgcctgaa ctatggttct cctgataaac cagaagtttt ttgggaatta
     3901 tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt taggaactcc tgttatttca
     3961 ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa tctatccaac accaatgatt
     4021 ggtatggtcg gattgattga ggatcataaa catatcacta ctcaggaatt caaaaaatca
     4081 ggggatctaa tctatatatt aggtaagacg tttgcagatt ttgatggcag tgaattacaa
     4141 aagatgcagc ttggaagaat cgaaggtgtg atccgaaact ttgatctatc cattgaaaag
     4201 agaaaccaag agttagtatt gacagccatc caaaacggat tgattgaaag tgctcatgac
     4261 tgttcagaag gtggcttggc aattgcactg gcagaatcag ctttcaaaca tcagctaggg
     4321 atatctgtac agtttgaatt gtcctctgct caattatttg cagaaactca atcaagattt
     4381 gtgttgacag tcgcaccgga aaataagaca cgattcgaag aaatgatggg agatgctgct
     4441 gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa tttcagcaac tgacggtcag
     4501 atcaaaatag aaactgcagt agcaagaaag tgctgggagg atgcaatcgt atgtcttatg
     4561 aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt ttggggtcat ccagacgccg
     4621 ctagtgtggc atacttcggg ctccatagtc ttcagcatcg aggacaagaa ggtgcaggta
     4681 tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga tttggggctg ctttctgagg
     4741 tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga agctgcaatc ggacatgtac
     4801 gttatgcaac agcaggcaat ggaagtgtgg acaatattca gccttttcta ttcaaatttc
     4861 atgatcagtc gatcggctta gcgcataatg gtaacttgat caatgctcgt tcccttagaa
     4921 aagagttaga ggaaaatggg gcgatcttcc attctaactc cgatacggag atattgatgc
     4981 atttgatccg acgaagtgaa gaaacagatt ttttaaataa attaaaaagt gctttgaatg
     5041 aagtcaaagg tggctttgcc tatttattaa tgacagaaac ggcaatgatt gccgctttgg
     5101 acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa aaacggagca tacgtgattg
     5161 cctcggaaac ttgtgcatta gaagttattg gggcacgttt tataagagat gtccagcctg
     5221 gtgagatagt gatcatcaat gacgaaggaa tccagattga ttgctttacg aaggacacgc
     5281 agctttctat ttgttcgatg gaatatatct attttgccag accagattca aacatcgcag
     5341 ggatcaatgt gcatactgca cggaaaaata tgggacggaa tttagcgaaa gaatcgccag
     5401 taaaagcaga tatggtcgtt ggcgtaccta attcttcttt gtcagccgca agcggttatg
     5461 cggaagctag tggaatccct tatgaaatcg gattagtaaa aaatcaatac attgcccgaa
     5521 catttatcca gccaacgcct gagctaagag agcaaggtgt tcgaatgaaa ttatctgctg
     5581 tacgaggagt agtggaaggt aaaaaggtga ttatggtcga tgattcaatt gttcggggta
     5641 cgacaagcag acggatcgtc catcttttga aagaagcagg ggcaaaagaa gtccatgtga
     5701 ggattgcttc tcctcctttg aaatatccat gtttttacgg gattgatatt caaacgcgta
     5761 aagaactcat tgcggcaaat cacacgattg atgaaatcaa agaatgtatc ggtgcagatt
     5821 ctttaggttt tttaagtgaa gagggtctga tcgaatcgat cggtctggaa aaagatgctc
     5881 cgtattcagg attgtgtatg gcttatttca acggagatta tccgacgccg ttatatgact
     5941 atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc gttcttttaa aagcagacca
     6001 agaagggagt atatgaattc aatggcaaat gcatacgcaa aagctggcgt agatgtcgaa
     6061 gctggatatg aagtagtaga acggatcaag aagcatgtca aaaaaacgga acgtttaggt
     6121 atgatgggcg ctataggagg attcggcggt tgttttgatt tatcggtctt tcaattaaaa
     6181 gagccagtcc ttgtctcggg gaccgatggc gtggggacga aattagcagt ggcaatcgaa
     6241 gcagacaaac acgatacaat cgggatcgac tgcgtagcga tgtgtgtcaa tgatatctta
     6301 gcacaaggcg cagagccgtt atatttctta gactacttag caacggggaa aaatgatccg
     6361 ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat gtgttcaagg aaatatggcg
     6421 ctgattggcg gagaaacagc tgaaatgcct ggtatgtact caggtaatga ttatgatcta
     6481 gccggatttg ctgtagggat agctgaaaaa tctcaattat tgacaggaga aacgatcaac
     6541 ccaggagatg tgttgcttgg aatagcatct agcgggattc attcaaatgg gtactctctt
     6601 gttcgcaaaa ttttctttga gcagcagcag ttttctttat catcaaaact gccagaattg
     6661 aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa tctatgtttc ttccttgctt
     6721 ccgctgatca aagaaaagaa aataaaagga gctgcacata tcactggtgg agggtttgta
     6781 gaaaatatcc cgcgaatgtt accagaatct atggctgcac aaatcaaact tggctcatgg
     6841 ccgattcttc caatattcgg ctgtttacaa aaatatggtg aaattcctga gatggagatg
     6901 tatgaaatct tcaatatggg catcggtatg gtcctggcag tcgaagaatc gaaagtaaaa
     6961 gaaatagtac acgaaattga gcaagctggc gaaaaagttt atgaaatcgg gaaagtgatc
     7021 gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac gatgagaatc gctgtttttg
     7081 cttctggaaa cggaagcaac tttcaagcgc tagccgatta tctatcgaaa aaaggattgg
     7141 aatcttcgat tgactggttg ttttgtgatc agcctgaagc atatgttttg aaacgtgcaa
     7201 ctgcgttgag tgtaccggca gattgttttt cacctaaaga atttgattca aaaaaagagt
     7261 atgaagaagc aattttgcat aaattgaaag aaaaaaagat cgatttgatc gtattagctg
     7321 gatatatgcg aatcattgga ccggtattgc tgaaaaatta tgataaaaga atcatcaata
     7381 tccatccgtc tcttttacct gccttccctg gtttgcatgg catacgtgat gcctttgaag
     7441 ctggagtaaa agaaacgggt gtcacaattc attatatcga ccaaggtgta gatactggac
     7501 caatcatccg gcaggaaaaa gtgagaattg aacaggagga cacgttcgat tctttagaag
     7561 aaaaaatcca tagagtagag catcgaatct atccagaagt gattagtgaa attattgaaa
     7621 atggaggcta tctgaaatga caagagcatt gatcagtgta tcagataaaa ctgggattgt
     7681 agcattcgcc caaggtttga ttgaacaagg agtagaaatc atttcaacag gaggaacaaa
     7741 gcatgcgttg gataaagctg ggatcaaaac gctttcgatc gaagaagtga cagggtttcc
     7801 tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa atccatggtg gtcttttagg
     7861 aagacgcgat ctccctagcc atatggaggc aatggaaacg gaaaatatcc aaccaatcga
     7921 ctttgtttgt gtcaatttat atcctttcaa agaaacgatt atgaaaccag atgtcgaaat
     7981 agcagaagct attgaaaaca ttgatatcgg tggtcctagt atgctccgta gtgcagcaaa
     8041 aaaccatgaa tttgtcacct ctgttgttga tccatctgac tatgaagaag tactttcaga
     8101 attacgtcag tatgggcata cttcactttc tttcagacaa aaactagcgg caaaagtctt
     8161 tcgtcatact gcggcatatg atgcactgat cgctcaatac ttaacggatt gggtggaaga
     8221 aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa caaacgcttc gttacggtga
     8281 aaatagccat caagccgctg ccttttatca gtccgctctt ctggaaaaat attcgatcgc
     8341 agcagcaaaa caactccatg ggaaagaact ttcttataat aatatccgag atgcagatgc
     8401 tgcgctacgg atcatgaagg aatatgacga gccaacggta gtcgccttga aacacatgaa
     8461 tccttgtggt attgggacag catctacgat tttagaagcg tgggaagcag cgtatgaagc
     8521 agatcctgtt tcaatctttg gtgggatcat cgttttgaat cgagaagtag atctgccaac
     8581 agcagaacag atgcataagc tgtttctaga aatcatcatt gccccttctt atacacaaga
     8641 agctttggaa ttactgcaaa aaaagaaaaa catccgatta ctgacagtag actttgcgca
     8701 ggaagaaaat caaaatcgag aagaaacggt ctcagtctta ggtggacttc ttgtacaaga
     8761 tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc gtgacaaaac gtaagccgac
     8821 tccagcagaa gcaaaagcat tagtgtttgc ttggagagct gtcaaacatg tgaaatctaa
     8881 tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc ggagccgggc agatgaatcg
     8941 agtcggttca gtaaaaattg cgattgaaca agcgcaagag aaaatggaag gtgcagtttt
     9001 agctagcgat gcttattttc caatggatga ttcggttgaa tatgcagcca aacatggtat
     9061 aaaagcaatc attcagccag gaggaagcat caaagaccaa gattctattg atatggcgaa
     9121 taaatacgat ctagcaatgg tctttactga tgttcggcat tttagacatt agagaggagt
     9181 cggataaatg aacattttgg tgatcggtgc aggtggtcgt gaacatgcaa taagtaaaaa
     9241 acttttagcc agtccgaagg tggatacggt gtattgtgcg ccaggaaatc cggggatgac
     9301 aaaagatggt atcaattgtg tcgctatcag tgagcgagat cattcagcgt taatccattt
     9361 tgttaagaaa gaggctattg attggagtat cgttggtcct gaagttcctt tgttaaatgg
     9421 gatcgtcgat gattttatgg cggaaggatt gaaaatcttc ggtccgacaa aagcagcagc
     9481 tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg gatacttatc aaatcccgac
     9541 agctaaatcc agaagttttg aatgttacga aaaagcagca gcgtatatca aagaaaatgg
     9601 tgcgccaatc gtagtgaaag cggacggctt agcagctggg aaaggtgtag tcgtggctac
     9661 cacagtgaag gaagcgctgg atgcggcaga acaaatgttg aaccagcatc gatttgggga
     9721 tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga gaagaattct cccttttggc
     9781 gtttgtccgt aataccaagg tgtatccgat ggtcatttcg caagatcata agcgggcatt
     9841 tgataacgat aaagggccaa atacaggcgg aatgggtgct tattcaccag taccgcaaat
     9901 ttcaaaaaag atgattgaaa aagctgtgga agaagtttta aaaccagcgg ctttgggaat
     9961 gaaagaacta ggacgctctt tcacgggtgt tttatatgcg ggtttgattg ctacgaagga
    10021 aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat cctgaaacgc aagtcgttct
    10081 ttctcggttg aagagtgact ttgcgcaagt aatcgatgat ttattagaga atcgtacagt
    10141 agagttaaag tggcagcaag aaggatacaa tgtaggcgtt gtggttgcag ctgccggtta
    10201 ccccgaagaa tatgagacag gaatggttct accagatttt ctggaagaag agctttctgt
    10261 ttactatgct ggagtttcct caaataacgg caaactagtt ggagcaggag gacgtcttta
    10321 tttagtagaa gcatacggtg agacgatcaa agaagcacag aaaaaaattt acaccgcgtt
    10381 aatggataaa acgacagatg gaacatttta tcgtacagat attggagaaa aagctgccaa
    10441 tagcgaactg atcgtgaagt aaatcagctg cttccattta taaaaaatac aacaaacata
    10501 atcggaagcg ccgattttag tgaagccttt tcataaagag tgtggtacac ttttgttgtg
    10561 tatataaata aggaggagtt cagatgaaaa aaattcaatt aggtacttct gatcagaaag
    10621 cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc ggaagatcca gtaaaagtga
    10681 ttgagacagc ttatgaaaac ggcattgatt tttttgacca tgcagatatt tatggaaacg
    10741 gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac atcaatcaaa cgagaagatc
    10801 tttttattca aacaaaatgt ggaatcgttc caggtgtgat gtttgatttt tctaaaaaac
    10861 atatcattga atctgtagaa aaaagtttga cccgtctgaa aatggattat gtggatgctt
    10921 tacttcttca tcgtccagat acattggtag aaccagagga agtagctgaa gcgtttgatg
    10981 aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag caatcaaaaa ccaatgcaaa
    11041 tcgaattgct gaaaaaatat gttcgtcaac cattagtagc taatcagctg caatttggct
    11101 tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa tatgacagat gaagcaagta
    11161 tcgatcatga cggtagtgta cttgattatt cccgattgca tgatatgacg atccaagcat
    11221 ggtcaccata ccagtatgga ttttttgaag gtgtatttat cgggaacgaa aaattccctg
    11281 aattaaacca aacattagaa gaactagcag ctaaatatca aacgacacca actggcttgg
    11341 cttctgcttg gattttacgc catccagcca atatgcaagt gatcgccggt acgatgaacg
    11401 tagggcgaat caaggaaatc gctcaagctt cagaaattaa tatgtctcgg gaagattggt
    11461 acgaattgta ccgtgctgct ggaaacattt taccttaaag attgtcataa gcaggtcaaa
    11521 agggctataa attaaaaaga cagaataact tgaaagctgt tttcagcttc gagatattct
    11581 gtcttttttt attgcaaatg gaaagagtat cattgtacgg atttcgttta ttagttattt
    11641 ttgtttttaa ggaaaagctg tgtccgatat tcttttggag aaatcccttg ttttttctta
    11701 aataaataac tgaaatagtt agggtcatta taaccaattt caaaagcaat atctgaaata
    11761 cgatagtctg attgctgcaa taattttttt gctaattcga ttctttgttc tgtcagataa
    11821 tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac tgaaatgaga gggacttaat
    11881 gcaacttgtt gagcgaccca agttaaggac atatctggat cggtaaaatt ttctttgata
    11941 aaatccaatg catggttcaa aattggctga tatttgttcc ttgaaggctg tgagggcaga
    12001 gcagttaaga aagaaatgaa catataaact gtcgaacggt aaagcgagtc gtcggcgctg
    12061 attgctaagc gttgactggt ggatgtgcaa tgaaccattt cttgcgggat tttcttttct
    12121 ttcaggcaga catgctggag tagcttagtc aagacaaata aacgatataa tcgtgttcga
    12181 gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact tagatacttc gtttttcgat
    12241 aatgaagaca aatcaagtga gaggtcaaag taaaagacag aatcaactgg aagtttcgct
    12301 tcttgaatca aatcctcata gctgataatt tgttctttaa gggaactggc ggtttcaagt
    12361 atcatctgcg tgatctcaaa agatgcaggt aattcgctga ttctttctgc gacaggacca
    12421 atggcgacag aaaaattatt tttttgtccc ttttctaatt catggaccaa cgtttgggct
    12481 acctgataac tggtctcgat cacattttct tcaagagaat caactattaa aaatttgatg
    12541 aatcgagagg aaacagcaga gaagatcact tgttgattct ccctaaataa aaacttcaaa
    12601 taatcactga gatgagcgta atcttcaaag tctgtactga cttggtttgc tgctaataat
    12661 acggtcattt ttttccctgc taaagagcga ttgaaagatt cagcaagttt caatgtttca
    12721 ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat gatttttttt caattcgaaa
    12781 acaagatcag aagaagtgtg cgtttctttt tgctgcaaat ctaaagcagt tactgctttt
    12841 tctattgctt gtttcaattc gctactttta atcggtttaa gcagataatc atctgcctgt
    12901 acctggattg ctcctttcat ataatcgaaa tcgtcgaatc cactaataaa tatgagacga
    12961 gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca acccgtccat gaaaggcatt
    13021 tggatatcag tcagaatgat gtcgggctgt aagtcgataa ttgaagacag tgccatctca
    13081 ccatctccag cttcgccgac ataagtgatt ggataataag aaccaaggac agttatttgt
    13141 tcccgcaagt tattgcgaat gaggtattcg tcttcgatga taaaaacttt atacatgttt
    13201 gtttcctcca attgttttgg gagatagagg gatcatcagt gtgacagttg ttccttctcg
    13261 gtatttgctg tcaatcgtga taggtttttg atcatttccg taataaagaa ggagacgctt
    13321 gtttacgttg taaagtccgt agccgatact gaaatctgaa tcgatccctt tggctaactc
    13381 tttacgtatt tctgccagtt tttctgcagg gatgccaatc ccgttgtcta taactttgaa
    13441 ttggatcatc tcatcaattt tgcatgtggt aatacgaata aatcctttgt gacggacgta
    13501 cttcgttcca tggtatacag cattttcaat caatggctgc aagatcattt ttaaaataga
    13561 aacaggaaaa agtgtttctg gtatatcgat cttatagtca agcatatggc cgtatcttat
    13621 ttttaagatg actagataat cattgatatg gctaatttct ttttcaagag gaatccagtc
    13681 ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt gcatgggtca tagtcagagc
    13741 ttcttcaaag cagtcttgtt cgatcaaaga aataatggca tccaaactgt tataaataaa
    13801 atggggagta atctgagctt gcaatacacg aacttcactt tgtgctaaat ggtattgttt
    13861 caaagcgttc tcccgtaaag actggtttag atcttccgcc attttattca tgctagcggt
    13921 aagtgtttgt aattccagtg tttccggcag ggttaaacga aagccaaggt tccctgaaga
    13981 aagttgttct gacatctcga tcagctgatt gatcggttct tggacctttc tctctaaaaa
    14041 gcgacgattc tttttcgcat agaaaaaaat ggtactaaga actccaagtt ccactattgt
    14101 taatagaatg agcgagcgga caagtgtcgt attttttttg cttgctaagt cgatctccac
    14161 acgaacaaaa tcttgtaaga tatctgacag cagttgagtg acagaatcta cctgattgat
    14221 gatctcttca ttggtatcca taaaatcttt tgccaagata ttattgatca gctcgttttg
    14281 ataatcttcc agtgtatcga tcgtacgtag cgatacatct aacgtactaa tttctttaag
    14341 tgtatttgta ttatttttgc tctctcgaat atcattccta agttcttcta ggatattttc
    14401 ctcattgaac tcatctacgg ttacttggcc agaaatcaag tcccacatac tttccaaaac
    14461 tttttgatca accttcaaag caattgcatc tgctttttgg atatttgcga tcgtctgttg
    14521 ataaatcaaa agctgttgcg aatataacag tatgctcagt agcaaaggga taacagcaaa
    14581 tagaagcatg gctttgtttg cttgggcaaa aatctgtttt atgcttaaat tttttgtcat
    14641 gatacttctc cagtcaataa tttctggttg ggatgttagc tatattctgc tgggaaaaga
    14701 cagtctcgga aataaaaata tctttaggta atgtttttcc tgtttgaata tttccaaaat
    14761 aacgagtaac ggtattggct acataccagc cgacatcagg tttacactcg actacacaat
    14821 tgacgattcc tgagcgtagc ttctcgatca tatcttcttg tccatcaata gttacaatga
    14881 tcaaatcttc tccaggtttg attgatgttt cttttatcgc agctaaagca ccgtgagtca
    14941 tttcatcact atggctgtat aatacatcga tttcggataa atcatttgtt tctaaatatc
    15001 gtttcatctg gtcttttcct ttcatccgaa taaaatcacc gacaattcgg tgaacaatag
    15061 tcatcggagg tttatggtcg atggttccat ctttttttag ggttggttta cgattgattg
    15121 attccaaaaa tccttcggag cgtagcttgg tcggtgtgga gttctctgaa ccagcaagtt
    15181 ctaggattct gatttcctgt ttctttgaat ttgtgaagtg attgctgaca aataaacccg
    15241 cccgatttcc ttctgctttg aaactggggc caatgtgggt gacgaaaagc tcgggatcat
    15301 tcgtttgaat atgtctgtcg acaagtatga cagggatccc tgctcgcttt gcttctttta
    15361 atacagagtc ccacccggat tcttgcaaag gagtaaaaat gatcatatcc actttatagg
    15421 caatgaacgt ccgtatatct tggatttgcc gttcctgatt catgtagcca tttcggtaga
    15481 gaacttggta atcttctttt tcaagcgcag tgataattga ttcagtatgc tttttccgcc
    15541 agctactctc cgttcctgat tgcgaaaaac caacgactag tgggtcaggt gcttcctttg
    15601 tattaggtgt acaccccatc atttggtaag cgattacaac aagggctaaa aaaaataaaa
    15661 cacgtttcac tttaaatcac tccatctgga tttgttagta ctatcttatc agataaaagg
    15721 gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa gaaacttaaa aaaatccaag
    15781 acaaaaaaag tacacctaaa aaatttaaag taaatcccat aaaaaaatca atgttaacgc
    15841 tttctttatt agctatactc ggtgtatcaa ttgaaatggg ggataaaaaa tgaaaaacaa
    15901 atttagaaag attgttggga ctatcgctat tttgaccgca agcattctat taagtgcgtg
    15961 tggcaattca ggatctgcag atgatagtac ggggtatgta ggaatcgcta tgccgaccaa
    16021 atcagcagaa agatggatcg ctgatgggaa caacatggtc tcggaattag aaaaactggg
    16081 ttataaaaca gatcttcaat atggagaaga taaagtagaa aatcaagtag cacaaataga
    16141 aaatatgatt acaaaagggg tagatacact tgtgattgct tctatcgatg gttcggcttt
    16201 aactgatgtg ttagctaaag caaaagaagc agatatcaag gtgatcgcct atgatcgttt
    16261 actgatgaat tcagaaaatg tcgattatta cgcgactttt gataattttg gagtaggtgt
    16321 atcgcaagca gcttatattg aagagcactt aggattgaaa gaaggaaaag gaccattcac
    16381 gattgaatta tttggtggct cgcctgacga caacaacgca ctaatcaatt acaacggagt
    16441 gatgtctgtt ttacaaccat atatggacaa cggtcagttg gtcgtgccat ctggacagac
    16501 gagtttcagt caaatcgcta cgcttcgctg ggatggttct acggcgcaag caaggatgga
    16561 taatctgtta agcgcaaatt atactgacca aacattggat gctgttttgt cgccatatga
    16621 tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg gggtatggga gtgaaagtaa
    16681 acctttacct gtgattactg gacaagatgc gacagttgct ggcgttaaat cgatcattgc
    16741 cggggaacaa acacaaacga tctttaaaga cacacgtatc ttagcaaaaa atacgattga
    16801 aatgatcaaa gcaatcagtg atggagaaga ggttccggtc aatgatactg aaacttatga
    16861 taatggggtg aaaactgtcc ctacgtattt agcaaataca gtatctgtcg ataaagataa
    16921 ttatcaagca gagctgatcg acaccgatta ttataaagaa tccgatctga aaaattaaga
    16981 ggaaccaaac aaggaactaa agagatctaa gtcagagaga ggataagaat tatggcggat
    17041 tgtattttaa aaatggcaga tatcaccaaa aaattttctg gaatccgagc gttagattgc
    17101 gtgaatctga tgattgaacg tggggaaatc catgcattgt gcggagaaaa cggagcggga
    17161 aaatcaacat tgatgaatgt cttgagcggc ttgtatccat atggctccta tgacggggaa
    17221 atcttttatg atggaaagct gtgtcaattt aaagatttga aagatagtga agaaaaaggc
    17281 atcgtcatca ttcatcaaga attagcacta agtccttatc tttcaataaa agagaatatt
    17341 tttctcggaa atgaacaagc agaaagaggc gtgattgatt gggaactgac agaaaagaaa
    17401 acatatgaac tgctgaataa agtcggtttg tctatcgacc cgaatcttct agtatcccag
    17461 attggcgtag ggcaacagca actagttgaa atagctaaag cattatcaaa atccgtccgt
    17521 ctgttgattt tggatgagcc taccgctgca ttgaatgaag aagaaagcgc gaatttgctg
    17581 agattgatcc gagagttgaa agagcaaggt gtaacctcca tcattatttc acataagctg
    17641 aatgaaatcg tggatatcgc agatcgaatc accattttac gggatggaca gacgattgag
    17701 acactagaaa atgaaatgat cagcgaagag catattattc gcggaatggt gggcagagat
    17761 ttagttgatc gttatcctga aagaaaaccg gatattggag aagtttattt taaagtagaa
    17821 gactggacgg tctatcaccc tcttgatcac gagcgaatca taaacgacca catcaacttg
    17881 catttgaaaa aaggagagat tgtaggaata gctggactga tgggagcggg cagaactgaa
    17941 ttcgctatga gtctatttgg acattcttat ggaagcaaga tatccggacg tatattaaag
    18001 gaaggggcag agatatcagt taagaccgtt ccttcagcca ttgcaaacgg actcgcttat
    18061 gtctcggagg accgaaaatc tttaggactg aatctgctga tggatattcg ggaaaacgtg
    18121 acgctgagca gtttggataa aataagtcaa aaaggagtat tagataaaga aaaagaagta
    18181 actgaggcag aaaatttccg gaaaaagatg cgtataaaaa caaactccat ccatcaaatt
    18241 gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt tatccaagtg gctgatgaca
    18301 caacccgata ttcttttttt ggatgagcca acccgtggga tagatgttgg ggcaaaatat
    18361 gagatctaca cgattatcga agaaatggca gcaaatggca aagctgtctg tcttatctct
    18421 tctgaacttc ctgaaatatt agggatgtgt gatcgaatct atacgatgaa cgaaggacgt
    18481 attacaggag aagtctcgcg agaagatgca gatcaggaag tcttgatgaa attaatgacg
    18541 aaagaagagg tgggttaagt tggaacaggc aaaaaatctt acggataaaa aagagaaaaa
    18601 actaaatttg aaaagtagag cagctgatct ttttggtcgc tacagcatgg tgatcatttt
    18661 agcgggacta cttattgcgt ttcaattgat gacggatggt attttctggc gtccattgaa
    18721 tataactaac cttgttctgc aaaatagcca tatattagta ctagctgcag ggatgttatt
    18781 agttgtgctc ttaggtcatg tggatttgtc ggtagggtca gtgatggcgt ttgttggtgc
    18841 aattgcgggc atgatgatgg tcaatcgcca aatgaacccg tggatgacag ttatcgcatg
    18901 tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt tgggtagctt atgcagggat
    18961 accggcgttt atcgtgactt tagcaggatt gctgatgttt cgtggactga cacaagttgt
    19021 tctaggaggc caatctctag caccttttcc agctgttttc caaaaaatgt ctacgggtta
    19081 tttaccagac ttaagcgaag gaagcagcct tcacttcttg acattgattt taggaatgat
    19141 catcacgatc gtgttagttg ttggtcaatg gcgaacaaga aatcgtcgga aaaatcattt
    19201 atttgaagtg gaatctccaa cagctttctt ggtaaaggcg gtatttacag cagtcgttgt
    19261 actaggaata acttatatct ttgcctctta tcaagggtat ccgattattt tgatcattct
    19321 tggtttgatc gttgcagcat atgggttttt gacaaataaa acagtagcag gtcgacagat
    19381 ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca gggatcaaaa caaagcgaat
    19441 cacgttctgg gtattcgtca acatgggagt catggcagct ttagctggat tagttttagc
    19501 tgctcgattg aatgcggcaa cacctcaagc aggtacatcg atggaactgg atgcaatggc
    19561 ggcagtatat tttggtggtg cttcgacttc cggcggcatt ggaacaatca tgggtgcgat
    19621 tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg tcgattttag gcgtcggggt
    19681 agactggcag caggcaatca aaggattgat cttgctttta gccgttgtgc tagacttgta
    19741 taataagaaa aaacgaacaa cgtaggagaa cgccggttat tcagaaaaaa gactgtgaca
    19801 agacatttgt cacagtcttt ttttcgctaa aagcgaacat tcattgtttc gtttgtatag
    19861 actaaaaata atatatgttt ttttaccatt cgtataaatt ctctttttgc tcttgatttt
    19921 tttgcttaat tgagttaaat tacatagggc gctaaaaaaa gccttgatta aattaataat
    19981 gttcgtgttt tgctggatgt gaacatcagg aggataatgt aatgaaagta tttgattacg
    20041 aagatattca attaattcct aataaatgta tcgtaaatag ccgttctgaa tgtgatacaa
    20101 cggtcacatt aggtaaacat acattcaaaa tgccagtagt gcctgccaac atgcagacga
    20161 ttattgatga aacaatcgca gaattcttag cggaaaatgg ttatttctat atcatgcatc
    20221 ggtttgatga agcagctcga attccgttta tcaaaaaaat gaaaaagcgt ggattgatta
    20281 cctcgatcag tgttggcgtc aagaaagagg aatattcctt tatagagaag ttggcagaag
    20341 aatcgctaaa tcctgattat atcactatcg acatcgcgca tggacatgct aactcagtta
    20401 ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac ttttgtgatt gccggtaatg
    20461 ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg cgcagatgca acaaaagtcg
    20521 ggattggtcc aggaaaagta tgtattacaa aaatcaagac aggctttggg actggaggct
    20581 ggcaactggc agctcttaga tggtgtgcga aagcagctcg caagccgatc atcgctgacg
    20641 gtgggatcag aacacatggc gatattgcaa aatctgtccg ttttggtgcg acaatggtca
    20701 tgattggttc attgtttgcc ggtcacgagg aatctcctgg cgaaacaaaa gtcgaaaatg
    20761 gaatcgtgta taaagaatac tttggttctg cttcagaatt ccaaaaaggc gaaaaacgaa
    20821 atgttgaagg aaagaaaatc tggatccaac acaaaggatc tttgaaagat acactagtgg
    20881 aaatgcaaca agaccttcaa tcatctattt cttatgctgg aggaagagat ctggaagcca
    20941 ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt taatggagac acaatctaaa
    21001 aaataaataa aatattagga tgttgtgaaa aagttgtcct gcattaagta ataagaacag
    21061 ccaaacaaaa atagttcttt atatgttttg tttggctgga attattatcg cagatacaag
    21121 cttttgaaca tcattattca gaataaggga ctgtgataag atttttgtca cagtccctta
    21181 tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg gtaaaatcaa aagaaaaaat
    21241 agacaataga aaagagaagc ttatgtggga aaaagtagag aaaaaacaag gaccgattta
    21301 tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac ggaaggatca atcctggaag
    21361 tcaacttgaa tcagaacgaa aactagggca actttttggt gtgaatcgtt ccaccgttgt
    21421 ccatgcattg gaagagctta gggagcttgg ggtactaacg agcaaacgtg gcagcggatg
    21481 gtttgttaat cagactgaat gggggaaatt cgctgttcca agaatcgatt ggcggcaaat
    21541 gatctctcct cgttatgagc agacggactg gtatgagcaa aaaataagag aagcaaagca
    21601 gatccaaaaa acatcgtttc ttgatttata cgctagcgag atgccagatg agcttttgcc
    21661 gaattttgag tttccttctt attctcttga agaaatctta gcggaagaaa aagaaatgga
    21721 tcttttaggc tatactccgt tacgtaacaa aatcaaacgg tatttggaaa gtaaatttga
    21781 attggcattt tcccccaacc agcttcttgt gactggtggc ggtcagcaag caatcttttt
    21841 gattttacaa acgattcttt cagctggaga ggggatagct gtagagtcac cttctttttt
    21901 ttaccgatta cctcttttca aagcttcagg aacgcgttta tttgggatac cgatggatga
    21961 agaagggatc gacttagaaa aactgaaaga atcgatccat aaaaataaat tgaaagcagt
    22021 gcttatcaac ccgaattttc aaaaccctac aggaaaagtg atgagtcaaa aacgacgaga
    22081 aaagctagta gaattgtgtc gacagtatcg gcttccaatt attgaagacg atgtatttac
    22141 ggatctttca tttctaaacc aagaagaagt ccttcctata cgaacgattg atccggataa
    22201 tgtgttatac gtcggttcgt tatctagggt tttaggaaaa acaacgaaaa tcggttgggt
    22261 gataggacct gagactttta tctcgcaact agctcaagcg caagaaatga tggagttttc
    22321 gatgaatatc cttacacaaa tcacagtggc taatgtattt aatgaagcaa ttgatttgaa
    22381 aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga ctgataagcg cttggggaga
    22441 ttcacaatcg tttttcaagc ttcattcaat tttaggtggt tactatgcct ggattacttg
    22501 ggatgggaaa aaactagacc ccgaactagc agaaaaagta gtagatatgg gtcttggaat
    22561 tgcaccaagt ctactttttg ggcaagatat aaatggaatc agaatcaatt acagtaggct
    22621 ggatgaaaac caaataccgt tgttttattc aaagatgaaa attctagaaa agtggttaac
    22681 agaataattt cacaaagtaa atagattaaa gaatataaca gcttggattt aaatttcaag
    22741 ctgtttcttt tttttcggaa aaagaatacg atataaagaa actaagaaaa aaccattatt
    22801 tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg caacaaaact gtataacacc
    22861 aacgttttta aatagaaaca gatggttgta agtttgatta gaaaatagaa aaaatgcaga
    22921 tgaaatataa aacgctttcc ttattgtgat tttattcact aatgctgtta atatgcggat
    22981 tggcataatt tcctttcatc gtgaaaattt gtgcttttag cttgtatttc tcataaatcc
    23041 atgataattt attaatgaag acggttaaat agtgatacag ttttattcac tgtttcaatc
    23101 gcagaatgaa gagattttct tatagatgag agaggaatgt gtgacaaatg gcaaacaaaa
    23161 aagcaccgat cgacttccaa gcactgctag atgaagtcaa tgcagatttc ccagtatatc
    23221 aagcacttga tcaagatgga aacgtagtta acaaagattt agtacctgat ttatccgatg
    23281 atgaactcgt tgaattaatg actcatatgg tatggtctcg tgtattagac caacgttcaa
    23341 cagcgctgaa ccgccaagga cgcctaggct tttttgcacc aactgctgga caagaggcaa
    23401 gtcagctggc tagtgcttac gcatttgata aagaagatgt tcttcttcca ggttatcggg
    23461 atgtacctca actagtaaaa catggtttac ctttatctca agctttttta tggtctcgag
    23521 gacatgctgc aggtaattct tatccggaag aattgaaagc tctaccacca caaattatca
    23581 tcggtgcaca atatgtacaa gcagccggtg ttgcattagg tttgaagaaa cgaaacaaga
    23641 aaaatgtcgt cttcacttat actggtgatg gcggttcatc acaaggtgat ttttacgaag
    23701 caatcaattt cgctggcgct taccatgcaa atgccgtatt ttatatccaa aacaacgggt
    23761 atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa aacacttgca caaaaagctg
    23821 tcgcagctgg gattcctggt attcaagtcg atggaatgga tccgcttgca gtatatactg
    23881 tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg accagtccta atcgaaacac
    23941 tgacttatcg ttatggacca catacactat ctggtgacga tccaacccgc taccgtacaa
    24001 aagacacaga tgacgattgg cagaaaaaag atccattgat ccgcttccgt aaatatttga
    24061 cggaaaaagg actttggtct gaagaaaaag aagaacaagt catcgaagca actaaagaag
    24121 aaatcaaagc agctattgct gaagccgaca aagtaccaaa acaaaaggtt tcagatttct
    24181 tgaaaaacat gttcgaagta tctccacaat caatcaaaga acaaattgca atttatgaag
    24241 cgaaggagtc gaaataatca tggcacaaaa aacaatgatc caagcaatca cagatgcctt
    24301 agcacttgaa ctagaaaatg acgagaatgt cgttgttttt ggtgaagatg ttgggaaaaa
    24361 cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag ttcggagaag accgagtatt
    24421 cgatactcct ttagctgaat ctggaatcgc aggattgagt ttcggtcttg cgttagaagg
    24481 atttcgtcca gttcctgaaa tccaattctt tggttttatt ttcgaagcaa tggacgaagt
    24541 agtagctcaa atggctcgta caagatatcg aatgagcggc actagaaatc tacccatcac
    24601 aattcgttcg ccatttggtg gcggtgttca tacaccagaa ttgcattcgg ataatttaga
    24661 aggtttgatc gctcagtctc ctggtattcg agtagtgatt ccttccaacc cttatgatgc
    24721 aaaaggacta ttgatttctt ctattagaag taacgatccg gttgttttcc tagaacacat
    24781 gaaactatat cgctcattcc gagaagaagt gccggatgaa gcttacgaag ttcctttgga
    24841 taaagcagca gttactcgtg agggaacaga tgtatctatt atcacatacg gagcaatggt
    24901 gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa aatatatctg ttgaaatcat
    24961 tgatcttcgt acagttgcgc cattagatgt agaaacgatc attcaatccg tggaaaaaac
    25021 tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg ggcgttgccg cgcaagtagt
    25081 ttctgagatc tcagaacgcg ctatcctttc attagaagcc ccaatcggac gagtttctgc
    25141 acctgataca gtcttcccat ttggacaagc agaaaatgtc tggttgccaa atgcaaaaga
    25201 tatcgaagac aaagtaaaag aaatcgcgga attttaagaa aagaagggac gaaacaaagt
    25261 catggcttat caatttaaat t
//
LOCUS       DADQCX010000037        24421 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.037, whole genome shotgun sequence.
ACCESSION   DADQCX010000037 DADQCX010000000
VERSION     DADQCX010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.037"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(75..1442)
                     /gene="nhaC"
                     /locus_tag="J8R83_001392"
     CDS             complement(75..1442)
                     /gene="nhaC"
                     /locus_tag="J8R83_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAZ9574524.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1551..2972)
                     /locus_tag="J8R83_001393"
     CDS             complement(1551..2972)
                     /locus_tag="J8R83_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9574525.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3215..5092)
                     /gene="tdc"
                     /locus_tag="J8R83_001394"
     CDS             complement(3215..5092)
                     /gene="tdc"
                     /locus_tag="J8R83_001394"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAZ9574526.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDIPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5383..6639)
                     /locus_tag="J8R83_001395"
     CDS             complement(5383..6639)
                     /locus_tag="J8R83_001395"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAZ9574527.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            7219..8520
                     /locus_tag="J8R83_001396"
     CDS             7219..8520
                     /locus_tag="J8R83_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAZ9574528.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8589..9188)
                     /locus_tag="J8R83_001397"
     CDS             complement(8589..9188)
                     /locus_tag="J8R83_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574529.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9442..10323
                     /locus_tag="J8R83_001398"
     CDS             9442..10323
                     /locus_tag="J8R83_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574530.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10336..11946
                     /locus_tag="J8R83_001399"
     CDS             10336..11946
                     /locus_tag="J8R83_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAZ9574531.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12023..12682)
                     /locus_tag="J8R83_001400"
     CDS             complement(12023..12682)
                     /locus_tag="J8R83_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9574532.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(12965..13630)
                     /locus_tag="J8R83_001401"
     CDS             complement(12965..13630)
                     /locus_tag="J8R83_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574533.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13777..14382)
                     /gene="dhaL"
                     /locus_tag="J8R83_001402"
     CDS             complement(13777..14382)
                     /gene="dhaL"
                     /locus_tag="J8R83_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAZ9574534.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14410..15393)
                     /gene="dhaK"
                     /locus_tag="J8R83_001403"
     CDS             complement(14410..15393)
                     /gene="dhaK"
                     /locus_tag="J8R83_001403"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAZ9574535.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(15395..15790)
                     /gene="dhaM"
                     /locus_tag="J8R83_001404"
     CDS             complement(15395..15790)
                     /gene="dhaM"
                     /locus_tag="J8R83_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAZ9574536.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            15944..16264
                     /locus_tag="J8R83_001405"
     CDS             15944..16264
                     /locus_tag="J8R83_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAZ9574537.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(16376..17245)
                     /locus_tag="J8R83_001406"
     CDS             complement(16376..17245)
                     /locus_tag="J8R83_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9574538.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(17341..18642)
                     /locus_tag="J8R83_001407"
     CDS             complement(17341..18642)
                     /locus_tag="J8R83_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9574539.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNADTVPEPDALI
                     RYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLYA
                     YSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTLK
                     MLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVLF
                     AGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFAP
                     LYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(18639..19148)
                     /locus_tag="J8R83_001408"
     CDS             complement(18639..19148)
                     /locus_tag="J8R83_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574540.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(19323..21458)
                     /locus_tag="J8R83_001409"
     CDS             complement(19323..21458)
                     /locus_tag="J8R83_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9574541.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(21541..23196)
                     /locus_tag="J8R83_001410"
     CDS             complement(21541..23196)
                     /locus_tag="J8R83_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9574542.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(23198..23512)
                     /locus_tag="J8R83_001411"
     CDS             complement(23198..23512)
                     /locus_tag="J8R83_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAZ9574543.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            23682..23942
                     /locus_tag="J8R83_001412"
     CDS             23682..23942
                     /locus_tag="J8R83_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAZ9574544.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            23956..24270
                     /locus_tag="J8R83_001413"
     CDS             23956..24270
                     /locus_tag="J8R83_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAZ9574545.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
BASE COUNT         6965 a         5047 c         4404 g         8005 t
ORIGIN      
        1 aaaagcaatt ttcttgagtt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
       61 cttttttcct tccttcaatt ttttacacgt cgacgattca ataaaaaacc gcctaatatt
      121 gtaaagacag gtgcaagaat cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact
      181 ttcatcgttc ccataatgaa tgtgccgctg actccccacg gtacgagaga attgacggtc
      241 gcacctgaat ccgctagtgt tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa
      301 gaacgcttga atgtttctcc tggaagaatg atggacagat actgttctcc aacgatcaga
      361 ttgattccga tacagctcaa ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt
      421 tcttttaatt cttgaacgat ggtatcaacg atcagatatt tgatcagtaa cccacctaat
      481 gccaatgcaa gtaaaatcaa actagcagaa cctaacatac tcatgatccc gcctcgagaa
      541 agcagttcat ctagctttgg atcaggtgta tttgcgacat aaccattcat caagatgtct
      601 gctgcttttc cgaccgtcaa acttttctca tggataaaag aaagaacgag agcagctgtc
      661 gatcccgcta gtaatgtagg gatagccgga atttttttga ttgccccccc aaataaaata
      721 actagtggaa tcaatgtcca aggagagatc caaaagctcg ctttcatgtt ttggatcatt
      781 tcattgatac tagctagatc ggctgaatga ctgttatgtc ctaatatcgt ataaaaaatc
      841 aacgaaagga cgaatgctgg gaaatccgta taacgcatac cagcgatatg ttcgaataga
      901 ttaactcctc caatacccgc tgccaagttg gtcgtatctg ataaaggcga gcagttattc
      961 cctaaaaagg caccggaaac gactgcgcct gtagtcattg catcattgaa tccaagtaaa
     1021 tgaccgatcc ccaaaaaagc aattccaatc gtcgaaatcg ttgtaaatga actgccgaca
     1081 gtcactccga caattgcaca aacaagaaat gctgtcggta aaaagaaacg cacagaaaca
     1141 agtttaaatc cataaaccat aatcgtaggg atggttccag ataaaatcca tgaagcaact
     1201 aagacaccaa tcaaaagaaa aatcaggatt ggaatgatcc ctggagtgat tcctttgatg
     1261 atcccgtcat ggatctcatc ccatgtgaac tttttaaatc tgccataaaa caacaaacac
     1321 atgaaagctg caaggatcgg gatatgtggc gagagctgga atccgatgat cagtactcct
     1381 aggagtgcca acaacacgat caatacagcg atactttctt ttaaagaaat atttttattc
     1441 atcgtcgatc tcctatttca aatgaaaagg ccctgccatg aaaaaactat tcacttggca
     1501 ggacctccta ctaaatcagc gacaaaacgt cggctgaaag acttattttt ttatttttct
     1561 tctaaacttt tttctacctc aatcccccaa gaatctttct tgaagtgatt gatgatcaat
     1621 ggaataacga acatgaccac tgtgatagct gctactaata atgcatcact caatgtcgct
     1681 gtacctaatg tagcaaatac gacaacgatg atagagaaga tcagcatgca gctgactacc
     1741 caagctaatc cgtttccgtt tttaccaatt cggtaaggac gttcgaattc tggatgtttc
     1801 ttacgcattt taagcaatga aacagcaatc aaaatgtaca cgatacaata aataacagtt
     1861 gtagcatttg taagtgtcaa gaatacagca cttacgtcat ccattacacc ataaagcaaa
     1921 gcaaataatg aaataacgat tgattgtgtt agaacgacat ttctagatac gccgtatttg
     1981 ttttctttat ggaatccgaa ttttggtgga aggaatcctt cacgagctac ttggatgatt
     2041 gtttttgatg gtccagtaac ccaagctgat aattgtaaaa gcacaccaat aaataccatg
     2101 aagctgaaga tatttccgat cacttctggt aagcctagga tttgacagtc aatcaagata
     2161 ggctgcgtga tatttgctaa ttccattttt ccatctggta cgacatttgc tacaagcatc
     2221 gcattgatga cattcaataa aactaatccg atcaaagcga taaatacgcc ttttgtataa
     2281 ttttttgttg cgtctttcaa acgaggcatg taaacagaac tcatttcgat cccaacaaaa
     2341 ataaatgtga taccagctaa gtatttcaat gaatcaatat gttccaagtc agggaaagct
     2401 tttgaccatg aaaagtcacc tagatagccg tttgagacta gtccgacttt gaaggctgcc
     2461 aaaacaccta aaacgaacat gatgactact gggatatata cccctagcca tacaccgatg
     2521 ttcccgccga cttttgccat atcgaatttc aagttcaaga tcgtgatgat ccagtagata
     2581 actaaaatac aacctaaaac gaaccagtga ttattgccaa gttctacatt accaaatgtg
     2641 tttcctaaca atggtcctaa agtagaagcg accattacca tacctgggaa catttgcacc
     2701 cataatagcc atgcaacgac aaatccccat ttgctgccca gtgctgtttt tacccataac
     2761 tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac cggaaaccat tgatatcgga
     2821 ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca atgtccaacc gactgcggct
     2881 aacgtaggaa tactccgaac cgttgcacac agtgccattg tcagaccgat aaaggtccca
     2941 agacccattt tacttacttc agatttactc accgttgaca ctctccttga ttttttggat
     3001 aaaataacgg tgtctttgaa gtagtttcag caataaacga aacaattcag cgaatatttg
     3061 aggggattct ttgagtttat tgcttgaagg gtttcttcaa agacaacctc aaaacaaagg
     3121 gatcgaagag cttaggtctc cccttgctct tcagatccaa acatgcgtca gaaacagtta
     3181 gtattcaagc tgttttctaa catgattacc ttgcttattt tgcttcgctt gccaataatt
     3241 ggtctgcgta gattttttcc aatttttctt gaagagctgc tttgattttt tcagcatatt
     3301 cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac gctggcacgc aatacagtta
     3361 cttttccggc acggttccat tcttcatctg agaatcctag ttggttcaca aattgtaatg
     3421 ggctgttgcc atagtctggg atagcaaagt cagtatgtga agttaagaac tcattaccgt
     3481 aaatgcttcc tttcacgtat gaagaataat catatacgtc atggttcaat ttattcattg
     3541 caactaagtc atcgttgcct ttttctttga atacatagtc taccatattg aaatctggat
     3601 aagttaatgg atgaacttcg atttctttgt ctcctacttt aaatgacaag tcattcaaga
     3661 agttgtagaa acgatgtgca ccttcgattg atgcacccat taatttacca tatcctgtga
     3721 cattcaaagg taagacatgg tgtgctgccc aaacgctggc tgctgttgcc cctgcttttg
     3781 aaccttccaa gatataagcc ccaagtaatg ctgggatatc tgcgcctttt tcaaatacat
     3841 atgtcgcaaa gtaagagata acgtctctca tgcggatatc tttgatgacg ataccaccgg
     3901 cagaatatgg aacatagccc attttatgtg ggtcaatcgt tacagattct gcttcttcga
     3961 ttgctttata tgcactgtgt acttcttcta agatataatc tttgttttct gtaaagacat
     4021 tgtatttgta atgaacatct tttaaatctt caaatggaat gaagttgttg tcttcgtcta
     4081 agaaaatcgc acggccgtat ccgccataag cagcatctac gtgtaagtag aagtaaatac
     4141 cgtctttttc taatacgcga cgcaatgcaa cgattttatc gataccgtcg attgctcctt
     4201 cttctgttga tcctacaaca ccgactacac ctaggattgg tgttttttca gctgctagac
     4261 cacgaacgat tttttcaagt tcgttgatgt ccatgcgata gttgtggtca actggcactg
     4321 gaatcacttg gtctaaaccg ataccgatga tgtcggcagc ttttagccat gaatagtgtt
     4381 tagtttgtgg aaccaaccat tttcctaatt tttctaaatg ttttccgcta cgtgctgagt
     4441 gagctttgat ttcgtcgatt ttttctggga cgctgtctaa cagattcatg atttcttctg
     4501 ttgacaagtt cattaattcc caatcgcttt ttccagcaac tagttcaggt gtcacttctt
     4561 tcattgcaag cggcaatgat ttgatgttgc gggcatacca aagtccttct aagtttgcta
     4621 aagaaccatc agcaacgatg tggccccagc catctttata gctcattaat tttgcaaatt
     4681 ccattcctac ttcttcttcc atttggcttg ttgcaggaga agattcatag gcaacgttat
     4741 taccattcca tagcatagca aaattgtacg ctagtaaaga tggcatcaat gtttcagagt
     4801 tcatatgacc ccagtaacgt ccggcattat gccaaggaac ggaatgggta cgcatccgcg
     4861 ctgaaatttc tgatagaaca tcctttgttt tattcacagt gtgttcaaaa ctagcactgc
     4921 ttttttcttc tggcgtaata ataggtatgt cttgaggcat gtagttttga cgccagccta
     4981 aatgttcatc caccaattca ttcaacaaag ctttatagat ttggccgttc tcagctttgt
     5041 ccccaatgaa tagggcattt aggtttagat ctttcgacaa tgattcactc atagtgaaac
     5101 cctcctaaaa aaatatttaa attttgtcga gccctacatt acacctgttc ttctattctg
     5161 taaactaagt tttggcctga tttttaatca tattttaata tgtatcaatt atccgaattg
     5221 ttcacacttt tgaaataatt aaaaaaaacg agggaattta caaatgtaaa ctccctcgca
     5281 aagattgtat taacgacaac cagcgttcta ttttaggatg ggtttcaaaa ttggaatgtt
     5341 gtaatagtat ttcccttttt caaggtaaaa acttactaaa ttctaatcaa ttactttggc
     5401 caaaaagtaa tttttcttac cttttcgaat aaccacaaac ttaccatcga attcatcgga
     5461 tggatttatg acaaaattta aatcggtaac gcggtcaccg ttaatactta tagctccgtt
     5521 tgaaacatct tcacgtgctt gacgtttaga tggttcaatt tttgtggaaa caagcagttc
     5581 cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc attttaccga atccttgcgc
     5641 gatttcttcc gcatttagtt ctttaatatt tccagagaac aatgcttgcg ttattttttg
     5701 cgcttctttc aagtcttctt cactatgcac aaatcttgta acttcttctg ccaaacggcg
     5761 ttgtgcttca cgtttctcag gttctgtctc tacttttttc gctaagtctt cgatttcttc
     5821 ttgagacaag aaagtaaaga atttcaagta tttcactaca tcgcgatcat cttgattcaa
     5881 ccagaattgg tagaactcaa atggtgaagt tttcttcgga tcaagccaaa cggcaccgcc
     5941 tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc aatgggatcg ttaaaccgaa
     6001 cgcttctgct tctggtcctt ctaattttcg gattaggtct aatccagctg tgatatttcc
     6061 ccattggtct gctccaccga tttgcaattg cacatcgtat gttttatgca gatgcaaaaa
     6121 gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat gagattccta cttccaaacg
     6181 gctggcaacg atatcttttg ctaacatcgt gttgatgttg aagtttttac cgtagtctct
     6241 caaaaattca agtaaagaga tttttgacaa ccagtcgtag ttgttcacaa atgtgatatt
     6301 tgcatcttta ccaaacaatt ttctcatttg attggaaagt gcgtccacgt tatgttgcac
     6361 ttgttccatc gtttgcaaca cacgttctgt tttgcggccg cttgggtcgc cgatcgttcc
     6421 tgttccgccg ccaatcagaa tatatggatg atggcctgcc aattggaatc ttttcatcat
     6481 cataaatgga atcaaatgtc cgatatgcat cgaatcacca gttggatcaa cgccgcaata
     6541 aagtgaaatg ctcttttctt caacgagctc gcgaagtctt tcttcgtttg tttgctgatt
     6601 aatggcgtcg cgccaagtta attcatcaat aatattcatt ttactgacct ccgtgtagtt
     6661 tttttatgaa agcaggaacc tgctagcata tgtaattaat tatttcttca ggataggata
     6721 ggaaataaaa aaagtccctt ggcatataag ccaagggacg aaatctcgcg gtaccaccca
     6781 atttgtatgt ctagatatcc aacatacctc tcgaacattt aacgctgtcg cgtggcaatc
     6841 actgccaaag actcctgaaa tgtaattcgc tttaaagcat gtactggttt gcagcgacca
     6901 ccagctttct gaaacattgg ctttaacaac tacttcgttt cgatcttcgt cttgttatta
     6961 ttaatatgtg tctatcatag agcgcaactt tttctttgtc aacagaaaaa ggatattttt
     7021 tttaaattcc tcattttttc ttttttgaat ccgctctaat tccgaacatt ttattttcaa
     7081 ttattgttaa aagaaataac tttttctgta ttttttctgc aatttatcga gaagtcactt
     7141 tactttgcct cttattcttt cttcgttaca ataaggaatg ggacaagtaa aaaaatgaaa
     7201 aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta ttttaggagc cacttctgct
     7261 ttaactatcg ttattttaat tctaagtttg ttttttgtca tccgatcatc tacaaaaaaa
     7321 gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa aagaaccgac agatgataag
     7381 caacaactag ttactcaagc aaaaaatctg gctcaaagct acgattatga ccaagcgatt
     7441 gcgttattgg aaaaagatag taagaacgga tctactgaaa cacaacagct tcttcaaaca
     7501 ctaaaaaagg agaaagaaca actgatcgac tggtctgatc ctactcagat ctctcatgtc
     7561 tttttccaca gcttgatcgt ggacccgcaa aaagccttcc actctcaaca ggcacaagga
     7621 tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt cgatcgaaca actttatcaa
     7681 aatgattttg ttttagttaa tttgaatgat ttgatccaaa aagacgaaca aggaaatctt
     7741 tcctttaacg ggcttgcgct acctgaagga aaaaaaccat tggttctttc acaagatgat
     7801 gtcagctatt atgaatatat ggataattcc ggttttccta gccgattggt cgtatcaaat
     7861 aacaatgaaa tcaaaaatgt ctataaagag aaagataaag aagaaatcgg tgactttgac
     7921 atggttcctc tgatcgatgc ctttgtcaag aaacatcctg atttttctta tcgaggcgca
     7981 aaaggtacct tggccctgac aggttacaac ggagttttag gttatcgaac atcaaaatct
     8041 caatatggag acaatgaaaa aacaaaaaaa gagattaaag aagctaaaaa agtggcggaa
     8101 cagttgaaga aagacggctg gagctttgct tcccatacat ggggtcactt gaatatgact
     8161 caagcttcac tagaagatgt aaaaaaagac aatgaattgt ggcagcaaga agttgcacct
     8221 atcctaggaa aaacaaatat tctgatttat ccatttggtg cagacatcag cgactggcag
     8281 ccttattcag cagaaaatca aaaatttgct tacttgaaga gtcaaggttt cgatattttc
     8341 tgtaatgtcg atgcttctac accagcttgg ggacaattag gtacggattt ctatcgaaat
     8401 gctcggatca atatcgatgg cattcgtttt caatctgatt tagacggaaa aaatcctatt
     8461 cttgatccat tcatcaatgt ccatgatgtc tatgacaaag aagcacgcga atctgcttga
     8521 ttttacgtca tttatgaacc aaaaaagccg aactgacatt ttatcgtcag tttcggcttt
     8581 tttatgcttt atttcttctt cggtgcgatt cccttgatca ggacttctgt ccattctgct
     8641 gtatatggaa gcagttttgc gtatatctcc ggcttagaaa ttccttctac cattgcttga
     8701 aaatagagga tcaagaactc atccgaatat ttcaaatcca cttttccttc tttccgccct
     8761 cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg tatacgcatc catcgcgtca
     8821 gaaaattctt ttttttcttt ttttgtatag tatgtcatca aatcgatata aaattgtttg
     8881 ttcactcgat tgagataacg gattttgttt tcactcatgg caatcagtgt ttcttcaaat
     8941 ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta aatcattcat aaatgcaaaa
     9001 aatacttcat aaatcagccc ttccttgctg ccaaaatatt taaaaatcgt cgctttactt
     9061 acctgagcgt tctcagctac cttatccatt gtcactccag cggttcctat gtctgtgttc
     9121 atcaagtcaa aagctgcttg taaaatctct ttctttttct cttgtgctct cttttcaaaa
     9181 ccgttcattt gtagagcctc ccgtaatttt aaacttttat aatatatata gttcaaattt
     9241 attctgaggt ttattataac tatctattga gaaagtatca agctagcaat tccttgttta
     9301 tgaattcatt gacagaaatt tataaaaaga atattatgta ctaaaataat aaaaaaagtt
     9361 ttataaaaag gtataaaacc tttttattaa actatttaat cttgtttagt atatattttt
     9421 agaaaaagga gtggggtttt tatggcagaa atcgtcaaag tcacacattt gaaaaagagc
     9481 tttggtcgtt tcgaagcttt aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt
     9541 ggatttatcg gaccaaatgg ttctggaaaa tccacgacga ttcggacact tttagggatt
     9601 ataaaaaaag acggcggaac ggcaacgatt tttgggcaag atgtatggga agatagttta
     9661 tctatccatg aacgtctttc ttatgttcca ggcgatatct ctttgtgggg aaatttgact
     9721 ggaggagcga tcatcgatct cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa
     9781 gatgaactga ttcaacgttt ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa
     9841 ggaaatcgcc aaaaagtggg cttgattgct gctttggctg ttgattcgga tctctattta
     9901 tttgatgagc ctacttctgg tttagatcct ttgatggaaa cgattttcca agaagaagtt
     9961 gaaaaattga aagaacaggg caaatccatc ctactttctt ctcatattct cagtgaagtc
    10021 gagcgactag cggataaagt cgtgatcata cgcgaaggaa cactcgatga agaaggaaca
    10081 ctcgatgaat tgcgtcattt gactcgttcg accatcacta tagaaacaga agcagagaat
    10141 agtcacttag cacaattgaa cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa
    10201 tttgctgctg ataacgaagc tttcgatgtg attttagctg aagcgtccaa attaggtgtg
    10261 aaaaaatttg aatctattcc accgactctt gaggatttat tcatgagaca ttatgaagga
    10321 tgaggaggaa gcgaaatgac tgataaattt tcacgctggt ccaccctttt ttctcaaaac
    10381 cttagccgtg actggaaaaa gatcctgata tggctagtcg gtgtcactgc tttttctggt
    10441 ggttttgtcc ctgcgtttga agaattgact tccggacaag gattagctgg attatacgaa
    10501 accttgcaaa acccggcaat gattgcaatg gtcggaccaa ctccagcttc gaatgctgct
    10561 gagtatactt taggagcgat gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct
    10621 gctgtgatct ctgttttaca cgtggtgagc caaacgagaa aaaaagaaga acttggtctg
    10681 attgaactta ttcgttcctt tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct
    10741 gaaagtattc tgatcaattt gcttttagca atatcgatca gctgtacgat gatttttttc
    10801 caagcggatt cgatcactgc agaaggtgct tggctttttg ggctatctgt aggtagtatg
    10861 gggattttgg ggagtgccgt tgcactgttt gctgcacaac tgatgccaag ttcagccagt
    10921 tcgaatggtc tgtctttagc gtttttaggt ggactttacc ttctacgagc aataacagat
    10981 gtagctgatt cctccctttc gatgtggaat cctttaggct ggtcttattt gacctatcca
    11041 tttacaacta acaactggat tcctttgctt tatttgtttt tgttcagtct aatcttgata
    11101 atcagttcat ttgttttaga ggaacatcga gatttgaaca ccggctatat ccccgaacgt
    11161 gaaggaaaac cgtatgctaa acgttctctt ttatccttgc gtggtttatt attctatcta
    11221 aataaaggga tgacaatcag ttggcttatc acttttggtt tgatgggggc ggcatacggc
    11281 tctatctacg ggaatatgca acagttttta gaaagtaacg acttaatgaa acagatgttt
    11341 atccaatctg gcgtctcaat tgaaaaaaac tttacaagca cgatcatggt agtcttgatt
    11401 tgtctagctg ctattttacc aattgctagc atcaatcgtt tatttacaga agaaacccac
    11461 ggacgtatga atcagctgtt cgcaacaaaa atttctagga accaacttta ttggaccaat
    11521 atgttactag ctattctatt tgctatattg gcaatcctga ttagttctgg tgcactaggg
    11581 ctttctgctt tggcttcgat gaaggatgcg aaagacatgg atctattgat gtttcttaaa
    11641 gccgggttca atttcctgcc tgccgtttta gtgtttatcg gaattagtgg ctttctattc
    11701 ggatggcttc ctcgaatcgg taaacttgct tatatctact tagcttactc ctttgcactc
    11761 aattactttg gcggaatttt ggatttacca gaatggtttt ccaaaacagc tgtccctagc
    11821 tgggttccac ggatgccaaa cgattctttt gatctttccg tgttccttac gttatcatgt
    11881 atcagccttg cactgttcgt ccttggttct attggttata ggcgaagaga cttactagaa
    11941 ggataataaa aaagcatgta caatttcatg ctagcctcca aatctgggtc aaaaatccaa
    12001 catttggagg tcattttttt atttacaagt cttctaactg ctctttatca atgatccaga
    12061 cttctcgatt ctttcttttt acataaccat tctcctctaa taatttaaat tttctagata
    12121 aagtttcggg ggtcgtaccg ataaatgcag caagttcttt cattttcatt ggcaggaaaa
    12181 agtgatcctt ccctgtcgct ttagctaagt caagcagata gacagcgact cgttcttcta
    12241 ctttttccat catcaaaaaa gttgtctgct gctgtacttt tgttaatttc tcaacgttga
    12301 ttgctaaaag tttcagacta agggcgggat aatgcagtaa gagttccgag aaatcttttt
    12361 gtctcaatat gcaaatttcc gttttttcta gtgcttcgcc aaataaagac tcatttggaa
    12421 cgcctagcaa ctggctctct ccctcatatc cgcccggctc tattactcgt aaaagctgtt
    12481 cctttccgct agcagataat tgatacactt tcatactgcc ggaggccacg atcactaatt
    12541 gaggttctcc attcggcgca agaatctgtt ctcctttttc cacatagtga tgtttgacaa
    12601 gtgcgtgtac tttttcttga tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa
    12661 cacataaatg atcatgactc ataatctctc ctccttctaa acagctattt ctaataaaga
    12721 aacataactt cccttattcc aactgataat tttcttttat catagcataa acgtcaagcg
    12781 aaccagatac cagcaaatag agtggatttc tttttgtccc ttgctttatt ttccttcttt
    12841 tgagacctta agtaattgat tcctatcaat tttttaaata tttacttttt gaataatcaa
    12901 aaacaaacct tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg
    12961 ttgtctattg aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg
    13021 tttcagcggt tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca
    13081 tttgaaaggt tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca
    13141 aatagtcaga caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat
    13201 aatccttgat atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg
    13261 ctgcaatgct accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt
    13321 attgtttttg attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc
    13381 ggtacgcgct ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag
    13441 gtttgctcat gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc
    13501 atttttgcca gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc
    13561 tctctttgag ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc
    13621 caagttccat tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata
    13681 tggacaaata gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa
    13741 aaaactgcga tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa
    13801 aagcgttgaa aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg
    13861 ctctcctaga taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc
    13921 ctggtcaatg atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca
    13981 aacatctaac atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt
    14041 tccctgctcg atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt
    14101 cgctttcatc atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt
    14161 cgatatcatc gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc
    14221 ttgaaaagct tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc
    14281 gccaatcggg gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa
    14341 ttgcgtgagc cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct
    14401 tgagattttt taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt
    14461 ctccgtcaag tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt
    14521 accgactttt cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt
    14581 catgaacacg aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc
    14641 ttcttttggt aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac
    14701 tttagaaggc tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata
    14761 ctcgatctca tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc
    14821 tcgaagcgct agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa
    14881 ctcagctagg gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt
    14941 acctgcaact ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc
    15001 tacgatcaca ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa
    15061 gttcaatgca tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc
    15121 ttccttaata gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac
    15181 cgctgcactt aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc
    15241 tccaccagaa accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga
    15301 ttctacacga tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac
    15361 aatattgctt ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat
    15421 tttgtgcttc tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg
    15481 caaaagctcc ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt
    15541 ccaacatgtc ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa
    15601 aataactagc tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc
    15661 cgatctcgcc atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct
    15721 gctcaatcat ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac
    15781 tttttttcac aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca
    15841 ttaatgaaca attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt
    15901 cttgaagttt gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac
    15961 gaacagtgta gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat
    16021 tactgggatc catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg
    16081 ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc
    16141 cgaacgtgca aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt
    16201 attaggcagc gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag
    16261 ataagtaggg gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa
    16321 gaattagatt tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt
    16381 tctttttgcg gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat
    16441 aactgacaga agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg
    16501 gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg
    16561 ccgaatgcaa aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt
    16621 caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg
    16681 ctgtgatatc cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta
    16741 attgctgatt gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt
    16801 ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt
    16861 tatttttaag atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt
    16921 ttgcagcttc taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat
    16981 cgatttggtc agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt
    17041 ctcctgaatt atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag
    17101 caccagaaga gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa
    17161 aagctgtctg tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca
    17221 ttcttttttt catcactttt cccatcctta ctacttttta actaatttct tattataagc
    17281 aaaaatgttt ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt
    17341 ttattttttt gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt
    17401 gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat
    17461 atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga
    17521 agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt
    17581 aaaagtaata taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc
    17641 aaaaagaact acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat
    17701 gaagatgatc gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt
    17761 cagccagact tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa
    17821 cgtcacaggt acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt
    17881 taactgatga tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc
    17941 cacatcgatc aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc
    18001 accgaaaaca gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt
    18061 ttgagatttt gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc
    18121 aatatgtctt gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc
    18181 cggtaccgtg tctgcattgc ttaaaatcaa tttccctttt gcaaaggcaa gtccgatatt
    18241 aaacgcgtgg gcttttcctt tatttttttc gatccgaacc acacgaagat tagcgtattt
    18301 tttcatcagt ctagctaata tttctggtgt ttggtccgtt gaaccatcgt ctgtcactaa
    18361 tacctcatag ttgtgataat tcaatttcgt catcaaatac tcgattgtat attcgatcac
    18421 aatttcttca ttatgggctg gcaccatgat cgtgatgaac ggttcgacac tcaagggaac
    18481 atctacccat tctttttgct tatgtttgta taaaaacaca taacaccaga caccaataaa
    18541 ccatacaaat ccgcctaaaa tcggataaga aacgagaaaa aaatacataa tagacaaaca
    18601 agtatctaag aataaattac ctgtatgggt gattgagatc atttcagttc caccccattt
    18661 tctttataca aatctgcaat gaatgtcgta tctagatttt tctcttcgga gacagaataa
    18721 aaacggaccg tttctctctc ttcttttgtt ccaaaacgtt ccgtatacac ttcttcaagt
    18781 aattcttgtc tttttttcaa tttttcatct tcatattcaa aagatttatt tacttttttg
    18841 tatagatttc gattgttcca cctagtcaat acaaatgagg taatcaggaa actgaaaaaa
    18901 atcaatacaa aaaagccgat taagaaatac agcattttct tttctgataa aaaagcgtac
    18961 aaggaaaaat ccttggctct ttctggtctc gttaatggga aaaagaccca tataaaagga
    19021 agaacaacga tcatccatcc taaaagagcc actaacgttt gccaaatctt taaccagtaa
    19081 ttaccttttg aaaaatactt atctttcacc aaaattgatg caacttcttc tcttgttact
    19141 tttttcatat cctcacctca cgtttttttg ttacgacgta ggagtttacc atacatttca
    19201 tttcttttca cataaagtgt tcctaaattt ttcctaagaa aaagaacaaa acatttctca
    19261 tcagcaaatg aaaaatattt tgttcttttt atcagttgtt ctttttattt tttatctctt
    19321 aattatgttg ctctttccaa tacgacaatg cttttcattc ctctagatat cgccgtgtac
    19381 atttgtctgc gtcttctttg ctcatctcca tcgttttcaa atggatataa gattacatga
    19441 tcaaattcca gtccttttgc tagactcaaa ggaatgattt ggcagttttc taatccatat
    19501 gaattttttt taatcgattc ttgtagcgtt tgggtttcct cttctgtttg ggtgataact
    19561 gccgcttttt ctccttttag agaaaccaaa atctcagcta gtattttcaa caattcttca
    19621 gaggatcgaa aagagcggta ttcgggttct tttccttgcg gtcggatcga tacgatgtcg
    19681 atcttctctt gatccacagc ataggttttg aaaagctctg tgattgctcc gctagaacgg
    19741 taactatttc taagatcata ccgatggatc ggcagatggt agtcgtcgaa acaacgcata
    19801 atatcagcaa aagtagtgga agaattaaag attgcctgat tctcgtcacc tactaaagta
    19861 aagtgagttt ttggaaataa ttcgatcaat agacctaatt gtgccagggt ataatcttgt
    19921 acttcatcaa tcaatagata gcgaaatgct ggtacattta ccttttcaac aagtaaatga
    19981 cgaatagcta atataatgac tgcttcatca acagtacgtg tgggttgcca agcataagct
    20041 gagccatatc gtttttcata aattctttca aacaactgat gctcatccac ccatgccatt
    20101 tcttcgattt gtctggttat ttttcgatat tttttttgta aaagtttcct tgcataagct
    20161 acaatacttt gttccgaatc atcagaaatc aatttaccga ataattccaa ctgcctatct
    20221 tctgtcaacg agagtacctg attctgcaca gcaggacttt ttgcttgttt caaaagatga
    20281 ttcttccatt cgctcatcag tgcctttttc gttgcttgaa gcctatcgat caatttagga
    20341 tgagcaggaa ctttctcata tattttttcg atcgtttttt tagaaaggac tgtttttcca
    20401 tttttagtaa gtccacggat aaaattcgga tgatctaaaa acaaaggatc tgattgtttt
    20461 agattatcga taaacttttt gctacgcaaa cgttctgtct gctccgatac attttctccc
    20521 gtgatacgtt tgaaataagc ctcttcacct tctatttcct ctgctgaaag ctgtgaaacc
    20581 agctgtatga tggttagatt cagtggattt ctttcaccta atgatggtag gacattcgaa
    20641 atatagtcga taaaccgatg attaggtgat agaatcagca agtcatcgga tgtcatcgta
    20701 tctcgatata aatagagcag atacgcaata cgctgcatga tagcagaggt tttaccactt
    20761 cctgctacgc catttaccaa gatattttga cttttcacat cccgaatgat tgtgttttgt
    20821 tccgattgga tcgtagcagt gatagccttc atttcattgg tctcatcttg gcctaagact
    20881 tctaataata cgtcatcttg aatagctaca gacgtatcaa aaaacttgac caaacgatct
    20941 ctttccaaaa gaaattgtcg tctttcttta ataaccgtat cgattttatt ttgacgaacc
    21001 gtataagaag atggaccaat catgttattg taaaaaagtt cggcaattgg tgaacgccaa
    21061 tcataaacaa gattttcatc tgcatcatct gtgaaatttg ctgtaccgat ataaaaggat
    21121 tcttttggct cattatccag aaagtctaca acgacttttc caaagtaggg acttttcaat
    21181 aaacgttcga tctttgctag ctgattttct gcgtttttct gtttgatatt catctgatcg
    21241 atttctctat ttttcatttc aatcatcgaa aaagtatcca ggttatctaa gtaactgtca
    21301 aaattcaatc gaagctcgcc agccatttct ttcaacgact ggtttccttc tatttttgcc
    21361 gtatccatcg attcccgcag ttcgtttttt ttatcaatta gcttttgata cacgttcttc
    21421 agatatgctt cttctaactg tttttgtgtg ttgaccatac acattctcct ctttttttaa
    21481 agtggtggaa ccgattagtt tacctctttt aagagtcgaa tgcaagcttt ttaacgagta
    21541 tcatttgtta ggatatatca gttcttcagg tcggacagtt tgatataaag aaaatgcacc
    21601 atcaaggttt tttacgtggt agccagactg cttcaagatt ctttccgcta gatagctacg
    21661 taatccgcta tgacagctga cgatatattc ttgttggctg tctaattcat ttaatcggtc
    21721 ccgaagttca ttcaaaggga tatgtttggc ttccttgaat ttgccctttt ccaattcttc
    21781 tgctgttcgc acatctaata aaatttttcc ttttgctagt tctgtcggca attcatgcca
    21841 ttgtacggtt tcactaagcc cttctgcaat gttcattgct gcatatccta gcatgtttac
    21901 tggatctttg gctgagccaa atggcggtgc atacgtcaat tctaattccg gtaaatcgaa
    21961 gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg atccgtttat ccacaccttt
    22021 tgccccaaca ccttgtgcac cataaatctc gccagtctct ggatggaaga tcaacttcag
    22081 taaaatatct gttgcttctg gataatagct tgcatgatct tttcctgata catgaatgac
    22141 ttcaaaagac agttcgtttt ctttggctgt tctttcactt aaaccggtgg atgcggcagt
    22201 cattccaaac gttcgtataa ttgctgttcc aataccgcct tgatttcttc gagaaattcc
    22261 ggaaatcgtg tccgcaactt gtctaccttg acgattggct ggtgaagcaa gagaaataag
    22321 tgcatctttt ccagtgattt gctgttttac aacgatagca tcccccaccg cataaatatc
    22381 aggaatattc gtttgataac gttcgtctac taggataccc ccgcgtatgc ctaattcgat
    22441 tccagcggtc actgctagct ggttatcagg acgaacacca atggataaaa taactaaatc
    22501 agcagggatg gtacgcccat catccagtcg caatcgtttc ccgtggtctt caaatccagc
    22561 gacagcatga gaagtaatca cttctactcc ttgatgagac aattcttttt ctataaaagc
    22621 tgccatttct tcatccagtg ttggaagaat atgtggtgct tgttcgatca ccatgacttc
    22681 taaacctctt ctttttaggt tttctgccat ttccaatccg atgaatcctg caccaacgat
    22741 cacggcacgc tttggctgtt tttctaatgc atgcatcact ttatcgatat ctggtacatt
    22801 tctaatagaa aaaacattgt cggcttctgt tatccctgga atcgatggaa caactggttt
    22861 tgcaccagga gataaaacca atgcatcgta ctgttcaatg tgtttttgac cctcatgtac
    22921 gacttctacc gttttgtttt cgggaaagat ggctgtcact tcatgatttg gacgcacatc
    22981 taaacaaaaa cgagcggata atgattctgg cgtttggaca agaagatttt cccgttcact
    23041 gatttctccc gaaagataat aaggcaagcc gcaatttgca aaagaaacat acggtccttt
    23101 ttcaaaaaca acgatttctg catcttccat taatcggcga agccgtgtag cagcagacat
    23161 tccacctgct acacctccga caataacgat tttcatctta tttccctcct actgttcgat
    23221 caaaccattg attcatgcca ccacgtacat tcactacatc ataaccagat ttctttaatt
    23281 ctttagctgc ttgtttactc ctcatccctg attgacaaat cacatagacg gtcttttctt
    23341 tgtctccatc atatctgttt atactttgta atggaacatt tttagctcct tttatatgcc
    23401 cgccccggta ttctgcaggt gttctaacat caagtaacgc tggattttcc aaaagctttt
    23461 cctttaattc tgggactgtt atcgatttta ttgattgaaa tagcaaattc attttctgca
    23521 cctcatttac atttttataa atacctcatg gggtatatta aacaggagct ttattaatat
    23581 gtcaaccaga atgactcttc atttttttca ctacttttta tatttgcata aaataccgat
    23641 aaggggtatt atctaattat aaaaatagag gagaatgtgt tatggagatt gataataaaa
    23701 atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg tggtatccaa aaaatgatcg
    23761 aagacgaaaa agaatgtatg gatgtcatca ctcaattaag cgctgttcgt tctagtattg
    23821 atcgcgtaat gggcatgatc gttgcagata atctgaaaaa ttgctttgag aaacctgata
    23881 gtaatccaga agaacaagcg gctaaactag aacaagcgat caagatgatt attaaaaagt
    23941 aaaggaatga tttcaatgaa agtcgttttc catattgatg aattagaaaa atggtcagaa
    24001 acagggaaaa acgtaaaaaa cctgataaaa gcttctccag aaacgacgat tgtcgtatct
    24061 gtaaatggca tcgcgattac cggttatcta gactctgcca atgcagaatt cttagatttg
    24121 caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg ctaatcatat ttcagaaagt
    24181 tctttacctg aacaagtaat cgttgtacca gcaggtgtcc ttgatttagt tgaactgcaa
    24241 tcccaaggtt atgcttatat caagccttag tcagtagagg ttgcgacaga agtgatcagc
    24301 ttcaagaaat ttcggcttat ttttcgaaga agctacttct ggaaaaccgt gaatcaaagg
    24361 ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agcttctcat
    24421 a
//
LOCUS       DADQCX010000038        24349 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.038, whole genome shotgun sequence.
ACCESSION   DADQCX010000038 DADQCX010000000
VERSION     DADQCX010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.038"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(131..1426)
                     /gene="purB"
                     /locus_tag="J8R83_001414"
     CDS             complement(131..1426)
                     /gene="purB"
                     /locus_tag="J8R83_001414"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAZ9574546.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1439..2572)
                     /gene="purK"
                     /locus_tag="J8R83_001415"
     CDS             complement(1439..2572)
                     /gene="purK"
                     /locus_tag="J8R83_001415"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAZ9574547.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2556..3044)
                     /gene="purE"
                     /locus_tag="J8R83_001416"
     CDS             complement(2556..3044)
                     /gene="purE"
                     /locus_tag="J8R83_001416"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAZ9574548.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3460..4767)
                     /locus_tag="J8R83_001417"
     CDS             complement(3460..4767)
                     /locus_tag="J8R83_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAZ9574549.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4770..5351)
                     /locus_tag="J8R83_001418"
     CDS             complement(4770..5351)
                     /locus_tag="J8R83_001418"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAZ9574550.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5467..5564)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5923..7215)
                     /locus_tag="J8R83_001419"
     CDS             complement(5923..7215)
                     /locus_tag="J8R83_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9574551.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7212..7835)
                     /locus_tag="J8R83_001420"
     CDS             complement(7212..7835)
                     /locus_tag="J8R83_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574552.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7838..8674)
                     /locus_tag="J8R83_001421"
     CDS             complement(7838..8674)
                     /locus_tag="J8R83_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574553.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8691..9578)
                     /locus_tag="J8R83_001422"
     CDS             complement(8691..9578)
                     /locus_tag="J8R83_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574554.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9594..10877)
                     /locus_tag="J8R83_001423"
     CDS             complement(9594..10877)
                     /locus_tag="J8R83_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9574555.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11560..12243)
                     /locus_tag="J8R83_001424"
     CDS             complement(11560..12243)
                     /locus_tag="J8R83_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAZ9574556.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12261..12878)
                     /locus_tag="J8R83_001425"
     CDS             complement(12261..12878)
                     /locus_tag="J8R83_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAZ9574557.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12888..13712)
                     /locus_tag="J8R83_001426"
     CDS             complement(12888..13712)
                     /locus_tag="J8R83_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAZ9574558.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13705..14265)
                     /locus_tag="J8R83_001427"
     CDS             complement(13705..14265)
                     /locus_tag="J8R83_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574559.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14439..15395
                     /locus_tag="J8R83_001428"
     CDS             14439..15395
                     /locus_tag="J8R83_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9574560.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15700..16656)
                     /locus_tag="J8R83_001429"
     CDS             complement(15700..16656)
                     /locus_tag="J8R83_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAZ9574561.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16760..17362
                     /locus_tag="J8R83_001430"
     CDS             16760..17362
                     /locus_tag="J8R83_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9574562.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17450..18949)
                     /locus_tag="J8R83_001431"
     CDS             complement(17450..18949)
                     /locus_tag="J8R83_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAZ9574563.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18965..19489)
                     /locus_tag="J8R83_001432"
     CDS             complement(18965..19489)
                     /locus_tag="J8R83_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574564.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19787..20536
                     /locus_tag="J8R83_001433"
     CDS             19787..20536
                     /locus_tag="J8R83_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAZ9574565.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20527..21312
                     /locus_tag="J8R83_001434"
     CDS             20527..21312
                     /locus_tag="J8R83_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9574566.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21281..21997
                     /locus_tag="J8R83_001435"
     CDS             21281..21997
                     /locus_tag="J8R83_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9574567.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22099..23118)
                     /locus_tag="J8R83_001436"
     CDS             complement(22099..23118)
                     /locus_tag="J8R83_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAZ9574568.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23137..24195)
                     /locus_tag="J8R83_001437"
     CDS             complement(23137..24195)
                     /locus_tag="J8R83_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAZ9574569.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7224 a         5235 c         4236 g         7654 t
ORIGIN      
        1 ttaaaatcag gttcctatta ttgataagaa aatataataa actaaaagaa gcagaaccgc
       61 taacggatct gcttcttttt tggttatttt tgctattcta ttttaattga attttgcaac
      121 tcactcttct ttattccaaa cctactcgtt tgaatatcac gtcaacgttt ttcaaatgat
      181 gatgataatc aaaggcatcg tctatttctt ctttagataa taccgatgtg atggttggat
      241 cttcttctaa cagcgggcgg aactgcactt ggttgtccca agcgtacgca gtttttggct
      301 gaacaagatc ataagcttct tctcttgtca ttcccttatc gatcaatttc agcataacgc
      361 gctggctata aatcaaacca aatgttgcag acatattccg cttcatgttt tcaggaaaga
      421 ccgttagatt tttaacgata ttgccaaaac gatttaacat gtaattcaat aaaatcgtgg
      481 tatcaggcaa gatgattcgt tctgctgaag aatgagaaat atctctttca tgccataatg
      541 tgacattttc ataggcagtg accatgtgtc cgcgcaccac tctggctaga ccagccatat
      601 tttctgaacc gatcggattc cttttgtgcg gcatagcaga agaacctttt tgacctttcg
      661 caaaaaattc ttctacttca cgtgtttcgg atttttgcaa tccgcgtatc tctgttgcaa
      721 aacgttcaat acttgtagca ataagcgcca tcgctgagaa atattcagca tgtagatccc
      781 gagggagaac ttgagtagaa atttcttgtg gacggatccc caattgttta catacatact
      841 cttcaataaa tggcgggata tttgcgaacg ttcccactgc tcctgagatt tttcctgctt
      901 ctactccttt tgccgcatgt tcaaatcgtt cgatgttccg tttcatttct gaataccatg
      961 tggcaagttt caatccaaaa gtagttggtt cagcatggac accgtgtgtc cgacccatca
     1021 tcactgtata tttgtgttct tttgcttttt cgccaatgat ttccgtaaaa cgtttcaagt
     1081 cttcccgtaa aatatcattt gcttgcttga tgagatagcc ataagcagta tctacgacat
     1141 ccgtacttgt tagaccataa tggacccatt ttctttcttc tcccaatgtt tcagaaaccg
     1201 ctcgtgtaaa cgcaacgaca tcatggcgtg ttaatttttc gatttccaag atccgatcga
     1261 tatcaaatga tgcatgctca cgaatttttt tcacatcttc ttgcgggatt tcaccaagtt
     1321 ctgcccaagc ttcatctgct aaaatctcga cttcgagcca cgcacggtat ttgttctctt
     1381 ccgtccagat attccccatt tcagggcgtg tataacgttc taacatgttt tttctcctct
     1441 aatcccaaat attcgtttgt ttgatttctt ccagcgtttg ctggatgtct tctgtcaaga
     1501 tagtgatatg tcccatcttg cgaccttttt ttgcttgttt ttttccatag aaatggaatt
     1561 gccagtctgg cttattctca atcaagcgat agctttccag cagttgttct cccaaaacat
     1621 tgaccattac tgcattgctt atcaaacgta ctttttctcc taatggccaa ccacaaatac
     1681 ctcgaatatg ggcatcgaac tgactcatag aacaagcttc aatagaataa tgtccagaat
     1741 tgtgaggacg aggagctaat tcattcacat atagcccgcc tgtttttgtt aaaaacattt
     1801 ctacccctaa aacacctgaa aggctcactg cttctgcaat cacacgggca atacgctcag
     1861 cctcctcgat cacatcctga tcaatcgcgg ctggagcaat cgtttcatga agaatattgt
     1921 tgtggtggat gttttccacg accggaaaag tcgtgaaatc tccttgacca tttcctgcca
     1981 ccatgatcga aatctctttt tcaaacggga tccatgcttc taaaacacag gttccttctc
     2041 ttaaaaggtc catggcagga gctagatccg cccgactttt caaaacatac tgccccttgc
     2101 catcatagcc gcctcgagtg gttttcaaaa cacaaggata gccgatcccg tcaatcgcat
     2161 cttggatatc cgtcggactg acgatcgttg cataaggagc aatcacgatg ttattcgttt
     2221 ccaaaaaaga tttttctaac aggcggtctt gcgtaatcgc aagcaagtct gtcccttgag
     2281 gaataaatga catgggtaaa atcgcattta acgcctctac actgacgttt tcgaattcat
     2341 aggtaatgac atctgttctt ctggcaagct ctttcagcgc aaaggtgtca tcatagacac
     2401 tttcaatatg ccaatctgca acttgtgcgg ctggacaatc gctcacagga tccagcacac
     2461 ctactttaaa gcccatttct tttgcactaa tcgccatcat acgacctaat tgaccgccac
     2521 cgacgatccc gatcgttgaa ccaggcaaca aaggtttaac caagttgatc actactttct
     2581 ataacagttt tagccaacat tgaacgtctt tcagccaatt tagcctccaa ttctaaatca
     2641 tacatggaaa gcatctgtat cgcaagtagt ccagcattaa ttgctcccgc ttttccgatt
     2701 gctgtagtag ctacaggtac tcctccaggc atttggacaa tcgaaagaag cgaatccaaa
     2761 ccatttaatg ttcgtgattg gaccggtaca ccgataaccg gcaaagttgt ttttgatgcg
     2821 accatacccg gcagatgcgc ggctccccct gctcctgcaa taatgatttt gattcctttt
     2881 tttcgagcgt tttgtgcata ttcaaacatc aaatctgggg ttcgatgagc agaaacgacc
     2941 tttttttcat aagacacacc gaattcatcc aatatttgac atgcttcttt cattgtttcc
     3001 caatctgaag tactccccat aatcacagag atttttgctg tcattgtttt tcctcccagt
     3061 ttttctacat tcatatttta acaatcactt tttttgatgt caaagaaatt tcgaatgtta
     3121 acaaagaaaa acattttatt gttcgtgttt attaaagata aaaaaaagga atgtgacaaa
     3181 agttaggtca cattcctttt tatggataaa cggtgttctc ctgccaactc ctcggtcaca
     3241 aggaacaata ttcaacaaac atgagaagct tttttttgaa attgttcctt gtgactcgga
     3301 gatgaacggc aggctcacga cctcttcctt caacggtgtt caatcagctg accctcggta
     3361 ttagctcaaa caaacggcaa aatacgagga actatttttc cgtttgtttc tctaacaatc
     3421 aggtcaaaac gctgatttca caacctttct tttgctctat tacttcttga aggcttcttc
     3481 caatatttct tcatcttttt tcaatccatt aaagatcaaa ttcaatatga tagccgtaat
     3541 gctactcatt acgatgccat ttccagtgaa catttgcaat gtttgcggca tttgactgaa
     3601 taatgtcggc gtaacattga aacccagccc aaatccaaca gaaacagcaa caatcaatag
     3661 atttttatca ttgctgaaat caacttccaa cagcatacgg attccttgga ctgccaccat
     3721 cccgaacatg actaacattc ctccaccaag taccggctca gggatgattt gtgctaacgc
     3781 accgatttta gggaataatc ctaaaacaat caagaagaat gcagagaaat agatgggttt
     3841 tcttgttttg attcccgaaa gttgaaccaa tccgacattt tgagaaaagc cagtataagg
     3901 gaatgtattg aaaataccgc ctaagataac ggcaagtcct tctgcacgat atcccttttt
     3961 caattcttct tctccaacat ttttcccagt aatgtcacca agtgcaaaat atacacctgt
     4021 tgattctacc atgctgacca tggaaatgat gatcattagt aaaatcgacc atacgtcgaa
     4081 agttggttta ccaaaataaa agggttgtgg aacatggaac aacggcgcat ctccaatcgc
     4141 gctcagatca atcattccca tgaaagcagc taagatgctt cctccgacta aaccaatcaa
     4201 taccgcgatt gaacgaatga acccttttgc cagcatttgc acgcctacaa ttaggagaat
     4261 cgtcacaaat gcaagtagca gatttgtttt gtcaccaaaa tcagctgctg ttgcattacc
     4321 tccacccatt ttctcgattg ctacaggaat caaagtcaaa ccaataacgg tgataaccgt
     4381 tcctgttact ataggaggga atagtttttt aattttagaa aagacaccag aaactaacac
     4441 aacaaagatc ccagaagcga taatagatcc gtagatagct cctactcctt cattggttcc
     4501 gatcaagatc agtggagcta ctgcttggat cgcacatcct aaaacgacag gcaagccaat
     4561 tccgaaaaat cggttaactg tcaattgcaa taatgtcgct aatccacaca taaagatatc
     4621 aattgaaatc aaataagtca tctgttcttg attaaagcct agtcctgtac cgatcaaaag
     4681 aggcaccgct actgctcctg catacatcgc tagcagatgc tgcagcccta aaaccgcagc
     4741 ttttccattt tgtgtttctt tttccacgat tatgcgtcct cctcaagaaa ctcaacttgt
     4801 ccattcgtca aggaagcaat acgcgcaaga gaaacgactc tcaatcccat ttcttcaagt
     4861 aactgacgtc catcttggaa agacttttcg atgacgatcc cgattccttc tacttgcgct
     4921 ccagcttgct ggcataattc gatcaatcct tttgccgctt gtccgtttgc caagaaatcg
     4981 tcgataatca atactttgtc ttctgaagat aaaaatttac gagaaataga aatcgtactt
     5041 gtcacttgtt tcgtaaaaga ataaacagaa gctgtcaata attcttcatc catcgtcaaa
     5101 ctttttgctt ttctagcgaa gatcattgga acatctaatt ctcttgcagc aaataaagct
     5161 ggtgcgatcc cagaagcttc aatggtcaca actttcgtga ttccttgttc tttaaatact
     5221 tctgcaaacc gttttcccat ttgttccatc aatacagggt ctacttggtg agtgacgaag
     5281 ctgtcgactt ttaatacgcc ctcgcctaat atacgtccgt ctttttgaat acgttcaact
     5341 aattctttca ctttatttgc tcctttatca tttattaata ccgaaataac cgcttttgtg
     5401 caaaaaccta ctatgtttct gttaaagaaa aacaccctcc actttatcat aagaaaagaa
     5461 gggtgaaata gccaatcttt tacttatagt ccagcattta cggtactggc tagaaactgt
     5521 catccatatt atgacgatat ataagtaggt atgtaaaact aataatagtg taaattcatt
     5581 ttcttgcaac tgttttgcac gtgaaggcag tttgccatat ttgaataaaa aatgttgttt
     5641 caaatattga aaacagtcta acactacttt ctgaaactga caacgtggtt tacttatttt
     5701 tttgtaaaat ctaatgattt ttaatgcatt attccttttt gttcgggttt aaatagttat
     5761 ttttattttc tcctatctaa aaaagcagcc cacataaaaa gaaggcatga caaaaagcat
     5821 gtcatagccc ctttttccga ataaatagtg ttcaaaagac agcctatcgg caataaggca
     5881 agattttata aactacggga agtaatttcc gtaaatctat tcttattctt ttaagctgac
     5941 aagctcgtca atcactactg cttttcctga agcaatagaa tgatttgctg cgattcctgt
     6001 caaaatcgac aaaataccat ctacgtgagt tgctgcccga ttccacggat cttcttcttt
     6061 ttcttcacca aatagatcat ctaataaacg cggatctcct ccgccatgtc cgcccgcttc
     6121 ttgttcgacg attacctcat atggctcacc gaacatcgga tagacatgga tggactgaag
     6181 aacggctgct ccttcatcct ttttatctcc acctgcattg atgtaagact tttcgatcac
     6241 tttcatttcg atccgtcctt tgctgccatt gaaagaaaca ttgaatcctt cccacggcat
     6301 atacgcgttt agcgaatacg tcaaaatcgc accagtttca tatttgaccg ttacgcctag
     6361 tgtatcttca atagagatat catcggaaaa tacactgcgg tcacgaatat atccactgtc
     6421 tttttctgct tctaaataca tttctcgcaa ttcctcattg gctgacaggt ctatagcaaa
     6481 tggatcagct ttagctagtt cgcttccata gcatcgactg taaaatattt ctactccgcg
     6541 tttctccgca ttatgcatcc cataaaagtt taatccaccg aatgcaaata ccttttgggg
     6601 acggctgttc aaccaaaaat tcactagatc aaaatgatgg gtagatttat gaacaagaag
     6661 cccgccgcta ttgtgcttat ttcgatgcca tcttctgaaa taatctgccc cgtgttgcgt
     6721 atttaacagc cattcgaagt ggatagaaaa cacatcacca atcacatcac tttctatcag
     6781 ttcctttatc ttcgtgtgat acggtgcata acgataatta aaagtgactc gcaggcttct
     6841 tcccgtctgt ttttggaccg ttattatttc ttgagctttt tcctcatcga tagtcagagg
     6901 tttttcgcaa ataacatcat atcctttttt cattgcacga atgatataat catgatgcgt
     6961 tcgatctact gacgtaataa tgacttcagc cggccgtacg tcatccagta gttgctcaaa
     7021 ttgtgatggc atacatgtct ttactttttt ctgtccatac ttgttcacaa gtatccgatt
     7081 tgcataatcc atccttgttt gagatacatc acaaaaaccg actagttcac aagtttgatg
     7141 atacgtagag gcaattgcct cataaaaaaa acgcgctctc ccaccaagtc cgacttgtac
     7201 atattttttc ttcatttaaa gtcattctcc ttttctttta agcaaaatac tgtgacaaat
     7261 ggcagccctg gatacagtaa tgcagtgagt aaaaaatcat gctgtataca ccagaacagt
     7321 ccatacaaaa ggcataaata ccacagaaac cccttgacgt tttttgacaa cagccagata
     7381 ttccttttga tcaaataaac aagactatct gctttatctt ctttgcagat atcaattagc
     7441 gtactaaaaa aactatggga tacaaaaagc aacagacaca atagaaaagg aatcagatac
     7501 caagctccaa tctttcccac taataaatac caatcaactg caaaaataat gacaaacagc
     7561 tgaaacaacg taatgatgaa acacatccgt ttgatttttc ctttcctcca acataccttt
     7621 ttttctgcca agtaatggac agatagataa taagaaggat acatcatcaa aaaataaatc
     7681 agatagacaa cacgagcaga cagcactaat cctaaagtga acaaacatcc tagaactaaa
     7741 gcgaaaagag cattactgat aagactggtt aaaaaaatcc gacagacata gtagttgagc
     7801 ttgtaaagaa acatctcttc tattggcttt ttcatattca gcccttcaga ccgcttgtac
     7861 tgatcccctg gacaagatat ttattgaaga ataagaaaat cagaaaaacc ggtagcagcg
     7921 acaacgtaga catcgcaaac atactcgcgt aagtcgtact agatccagcg tctgcaaata
     7981 atttgatggc aatcgatacc gtgtaagatc tcggcttgtt taaataaatc aatggtccca
     8041 tgaagtcgtc ccatttccaa taaaactgga tgatgatcgt cgtgatgatc gaaggtttca
     8101 gcaaaggaaa aataattttg gtaaagacac tatacttgct gcatccgtca ataatcgctg
     8161 attcatctaa ctctttgggg atgctgacca tgaattgcat gatctggtaa atgaaaaatg
     8221 cttgtccaaa aaaatgtggt aaaatcagcg gcacatacgt cccaaccaaa ttcagccgat
     8281 tgtaaataat aaactgcgga atcaaaatca cttgtgcagg aatcatcatc gttactaaca
     8341 tgacgacgaa ccagaatctt tttcctttga aatcgattct cgataatgcg taagcaatac
     8401 aagtcgagct cagaactgtc cctatcgtcg aaactgcaga gatgacaaac gaattcctaa
     8461 agaaagtaaa aaatgaaatt ccagcaaacc ccgcccatcc ttttgcgtaa ttttcccatt
     8521 gaaaagtctc tggaatcaaa ttcagcgaac cactcataat ctcttgatcc gttttaaaag
     8581 aacctgcgat catccataag accggataaa tcatgactag acctaatagc aaaataaaac
     8641 cgtattgaaa ccatttcgtt actgtattat tcatttcttc ctcctctcat tcacacaacg
     8701 acccattttt ttgatgattt gaaaatcaga aaggtgacag ctcccataat caacagcatg
     8761 atccacgaaa tagcactagc ataccccata gaattaaaag aaaaagcttg gttatacaca
     8821 taaagagcat aaaagttcgt ggcatcattc ggaccacctt gggtaatgat aaatgcctgc
     8881 gtaaaagtca taaacgccgc gattgtctgc ataaccaagt tatacaaaat gatcggcgaa
     8941 agaagaggta acgtgatctt gtaaaacgtc tgccatttgt tcgctccatc gatctctgcc
     9001 gcttcataat acgagcctgg gatctctttg atacctgcag caaagatgat cattgccgaa
     9061 ccgaattgcc aagcagacat caaaacaaga gggatcatga ccagtttttg atcgctaaac
     9121 caggaaagcg caggtgcgcc taatcgttcc aggaaaatat tcactaaccc gtttttagaa
     9181 aacaactccc gccaaactag agcgatagaa atactgccac cgatcaaact aggcacataa
     9241 tacaaagaac gaaagaaagt cgttcctttg atattcctcg ttaaaagata agcaatcaat
     9301 agaccaaaga tcagtttcac aggtacagat gcaaatacat agagaaaagt gactcggatg
     9361 gagttcaaaa aacgggcatc actcagcatc tttatataat tatccaagcc gatccatgag
     9421 actggatttc ccaaacgata atcggtgaac gaataataaa gtgacaagat catcggtatc
     9481 actgttatca atagaaatcc taggatgaat ggagaagcaa atacgtaacc gaccacattg
     9541 tcttgatcca agaaccgttt tagtttttct tttttcatgc cttcctcctg ctgctatcct
     9601 agaatgtttg acgcaaactc ataaagactc tctgctgctt cttctgctgt tacttcttca
     9661 taaatgactt tttcaactaa aagattgtat tggtcttgaa tttccggatt caaagcacta
     9721 tcaaagacat tcacttcgcc gttgtccata tcggaaatca tttctaaata atcaaatgtc
     9781 gcttgcaaag ttgcatcatc tgcacgagcg agctgttctc gaatattcga catgattggt
     9841 acaccacgtt ctccttttaa aatttcattg gcttcttcac tgttttgaaa gaaatcaata
     9901 aacttagcag cttcttcttt atgggctgag ctttttgcca tactcagcat ttgcgaagaa
     9961 cgtaaaggga taccagattc tccatctgct tttctgcgag gtggattaat caactgaatc
    10021 tccatatctt caggagcccc tgacaatatt tctgtcaact ggttacttga tagaaacacc
    10081 attgccgctt ctctatccct aaccgcctga aaagacagat ccgtcgtact tgcagctcca
    10141 ccacctggtt ctggatgggc ccctttgtct accagatttt tacgcagctg gaaaaaatct
    10201 gttagatagt ctggattttc aaatcccaag ctgttagata gatcttcccg attataaaaa
    10261 ttcaatcctt tctcaacttg tggtatttga ataatacagc cagctataaa atcttcgaat
    10321 cttgaaatag catagattcc taattcttca gtgatttgat agctgatttg ttcaaattca
    10381 tcccatgtcc aatttgaagc tggttcaggg atatttaatt gttcaaatat atttttattg
    10441 taagcaatcg caaacgaatt caccccgtta gacagtccaa ctaattgccc gtcgtaagtc
    10501 gtcgttgcta aataggattc atctgcatta gaaatatcaa ttatcccttg ctccacatat
    10561 tcatctaatg gttcaatctg attgatgtat tgaggaaatt gattgttcag ttggaaaatg
    10621 tcccagatat catctgatgc tgctagtgta cctaattttg tgtaatatcc ttcataatca
    10681 taaaattcat aatcgatcgt cacatgggga tttttttctt cataaagctc gattactttt
    10741 actgttgcat cgtgtcggac ttgcgaaccc caccaagcca tgttcagcgt gatttttttg
    10801 tcatcttctt gcccacaagc cgtcaagaag aataacataa cacttaaagc taagatgatt
    10861 ctcattcttt tcttcattct ctgcacctct acttccattg ttatttttca atatactgta
    10921 tttttataca gaacatattt attaaacgat ctttttcaag gggaataaaa accaagactt
    10981 gccttatcgt tctgcctagg atgaacaact caatactttc aagaaaaatt agatagtgct
    11041 gattcttctt tcatcgctaa aaacacttct tgcttcaatg atgggaggat aattacgcaa
    11101 agaaaaaagg atatcagaca actgcccaat atccttgaca tagctaaata agcatgcttc
    11161 ttcgtgtgcg ctcttcccta aaaaacagaa aaataactag taattctgta tgaaattagg
    11221 tacaatatac acgtcgatgc acaagcattg actatggcaa cttgattggt cagttcccgc
    11281 tgacttttca agccccgaca atttagctgc tactaaattg tcgggtgcct tttttagttt
    11341 ttattcgttt ttcattctat agaaagcgct tcaataaatc aagacatttt tttgttagaa
    11401 tgctaataat aacaaaaggt tttaactctt cttatgtaca ttacaggtaa aaaaacaaaa
    11461 aaatttctct tttttttgaa ttctgaacaa atagtactgg agtacaaaag acgaggaaga
    11521 gccactatct gctcttcctc gtcttttgat tctcacctgt tattcatgat tctttttctc
    11581 agtttcccga tatttttcca ttttacgact aaaaagctct ccgctacttg gtggcgtata
    11641 tgtgatggca tttgctcctg cttgaatggt ctcagcaata ctttcttccg ttggaccacc
    11701 tgtcgcaatg ataggaagtt caggatattt tttacgaaaa tggcgtactg cttctgcagt
    11761 ttctttacct gcactgatat tgataatcga aataccagct gctaactttt catctatttc
    11821 tgtatatttc gacgttaccg tactgataac tggaatatca actactcgac aaacttcttt
    11881 tactgtctct aaaggcgtag gaccgttcaa aacgacccct aacgaacctt gcgcttctgc
    11941 gaacatgctc atgtaggaag aacgagcacc ttgtgtcaaa ccaccaccta caccggagaa
    12001 aactggaatg tcagctgcct caataatgct tttagtaatc gctggatgag gtgtaaaagg
    12061 atacacagca attactgcat tcgcatttgt attacgtatg atcgcaatat ccgtagtaaa
    12121 gatgatcgaa cggatcaatt ttccaaatat cttgatcccg cttgcttcta aaatgatttc
    12181 cggtactctt acgatatctt ttctcaattc cgtcatgatt tctggcgtaa attgttctgc
    12241 catcagccac ttctcctttg ctatctccgg tcatactgat tcaattgata cgtctcgatg
    12301 acctggatga ttttttgcgc ataaccgggg tctgtcgcat aacctgcatc ttgcaatgct
    12361 tgtgcggctt cctgatagtt ggtggccgta atcacttttt catacagcgc aggattccaa
    12421 tctactcctt ggacgaacag ttgtgtatgg tcatccatgg actgttccca tgaatcatac
    12481 actttgaagt ctccttggat agttatccat tcttcgttaa caaattcctt tgtttccagg
    12541 cttactttct tctgatcccc ataagccttg atcccgaaaa gattattgta tttgctagcc
    12601 aaggtacttt ttccccaatt tgattctaat atagcttgtc ctaaaatgat actaggaagc
    12661 actccataac catcttgtag ttcttgggca tgcggaacaa gccgttcaat aaattgctga
    12721 tgggattgcg cttcattttc ttgctgatta tcagtaaaag gagaagacag attcttcaag
    12781 gaaaaaacaa aggctaagag tatcactgct acaccggcaa ccactgctgg ccaacggata
    12841 ttcttgcgct tttgcttttt ccactttttt ttcgccatga tcaattccta cttttcattt
    12901 aattcattca gatattcttc tagcgtcaat tggtgtttgg tgatatactc agcgttttct
    12961 ttaccgacat aacgtaagtg ccaaggttca tatgtgatct tagttatatc ttcgtgtcct
    13021 tttggataac gaacgataaa tccatactgc gcagcattat ctgcgatcca tttagctcca
    13081 ggctgatctc cgtaacttgc atccaataca gtagaaggat aactgttgta ccagttttga
    13141 tcgacgacat cgactgccag acctgtgtgg tgttcgctgt atcctggctc cgtaatcgtt
    13201 tctttagtaa tctttgtcgc ctcctcttct gatacacctt gacgactcat cacatcttgg
    13261 acattttgtt cgaaaacttg ttgttgggat gatacagacc ggtaagctga gaccatcact
    13321 aatggaaatc cagctgcttc agcagccttg gcaaatgctt catattctgg agcaatgcgt
    13381 ttgtcgatca agtatccgtt acttaatgat gccaattgag tagactcatc aatttctttt
    13441 tctaatttgt gatctggacc aaccaaaact agcttccaat cgtctgtttt aacatctggc
    13501 aattgtttgg acgtacgatc ttttgtttct ttgtccttta ccttgctgct ggttgtttga
    13561 ctgttctttt ctttactagc agttgttttg gtgcttgttc gttcgactgc ttgattgccg
    13621 gcttgaacat gcgaatcatc atcgctaaaa ataacatagc ccattgctgc gatcataatc
    13681 acaactgctc caaatcctaa aaatttattc acttgaaaaa tcctttcgtt gttcttcacg
    13741 ttccccattc gcctcatgaa cgtaagtttc ttccagattt tcattcaccc aatcgagaag
    13801 ttcgattttt tctccttcga tctgtttttg aacatctgct ggcagacgaa aattcaaaat
    13861 atcatcatag ccccattcat catattgaat acttactttc aagtcaaggt atctaccagc
    13921 ctgctgatta tttttcaaag ggatcagctc gacttttgct gctttgctgc taagccattt
    13981 ttgcgcgatg cgtgttttga tttgcttgta ctctgcaacg gcaacgtttc gtttttcggg
    14041 aaaaataatc gtttgacgca aaatcttttg cgttagcatc cattcataat cagtgaaaag
    14101 attttttact ttctgcatcg cttcagatgg cagatttttc tcgccatctt tccatttttg
    14161 ccattgttct ggactgatca gcaagtattc atctaaaaaa tttttttcag tttcaaactg
    14221 ttctaataat acactcataa taagatcaat atatacttga tgcacgttta tcccctcctt
    14281 ttaactattc tacttaagtt ttgatcaaaa agcacctctt aaatcgctgc tttcattttt
    14341 tttaatgttt caagtcctct cctctttatt cttcgtgatt tttgttataa taatagacag
    14401 acaagaaact caatccaact atgaaggagc gttttcagat gaaaaaatat caatggggaa
    14461 tcgttggtct tggtaccatc gcacatgagt ttgccgaaag cttcaatcaa gagacgagcg
    14521 aactaacagc agttgcttcc agaacttcag aaaaagcgga aaacttcgct caccgttaca
    14581 atattccaaa agcttacgga agctatcaag aaatgttaga cgatgctgaa atcgacatcg
    14641 tgtacattgc tgtaccaaat agacagcata tcgaccatat cttggcagca ttggaagcag
    14701 gcaaacacgt tctatgtgaa aaagccatca cgatgaataa aaaagaactg gctgacgcta
    14761 tgcgcttagc agaagaaaag aatttgatct tagcagaagc gatgacaatc ttcaacatgc
    14821 cactttatca gcagttacgc tcaataatgg atacaggaaa actgggggct ttaaaaatga
    14881 tccaagcacc tttcggcagt tacaaagaac cagaccctaa aaaccggttc ttcaatccag
    14941 aattagctgg aggagctctg ttggatatcg gtacgtatgc tgtatctttc gctcgtttct
    15001 ttttgagctc tcaacctgaa gtagttgcct ctacaatggt tccttttgaa acaggcgtgg
    15061 acgaacaatc cgtcactatc ttgcgtaaca aagaaaatga acttgctgct gtcagcttga
    15121 cttttcaggc aaaaatgcca aaagtcggta tcgttgcctt tgagaacggt tatgtgacga
    15181 ttgctgatta cccgcgtgct gatcgtgcgg agatcttatt tacagatggt acaaaggaat
    15241 tcatcgaaag cgggaataca tctgaagcaa tgaattacga aataaagaat atggtacaca
    15301 tgattgaagg tgacttgccc aatcgctctc tcttcttgac aaaagatgtc atcgaaatct
    15361 tggatcaaat gcaagttcta tggaaaaata tgtaatttta aaaggttgtg aaaaagctgt
    15421 tctgcatcaa gtaataagaa cagccaaaca aaaatagctc ctcctatttt tcgtttggct
    15481 ggacttatta ccgcagagga aagcttttga acaccgttta agaaagaggt tgtgagccta
    15541 ccgttcagct ccgagtcaca aggagcaatt tcaaaaaaca gcttctcatg tttgttgaat
    15601 attgtgactt gtgaccgagg agttgacagg agaacaccgt ttaaagaaga ggttgtgaaa
    15661 tcagcttttt gacctgaata ttagctgaat tcacaacctc tatttttgga ttttttgttg
    15721 ggagaattct gccttgattt caataaaact tttaaaagac tgcaaaaact ggaacaattc
    15781 tgctcgatcc tcgaattcag ggcgactagt cggcagaggc atttgccgat acaatacata
    15841 aacttcttca atacgtgtta aaatttgtct gccatcattt gactctgaaa atgtttctgc
    15901 agtataaatc aataaaccat agatatgttt tccataataa gctggttgct ggattctctc
    15961 tagattttcc agcatgtctt taatcacatt ggcctgtgct cttctcatag agaagtaagt
    16021 ttcgtagtat agcggctgtc tgagccagta gttttcttga tgttctctgg catcttcttg
    16081 gctttcgcga atgaatgtca gtaaatgttc gcatttgatc tgcacatctt ctttattttc
    16141 tgataaaaga aattctgcca tttgtctcaa aatatttcga aattcttttt cgatctgtat
    16201 ttggttttcc ttcagctgct tcgtacgatc tggcatgtaa acatttgcaa gcaaagcaaa
    16261 tactaatcca atcgccatta atcccgcttc attgccgatc agctgccaag acatgttttc
    16321 ctccactaaa taatgagtga ccaaaaccga atttactact atcccttcgg ttaatttgaa
    16381 gcgagaggca agcgggatga acaggaataa aaaaagactg aagccaaaaa tagtataccc
    16441 aacagcaaaa aaactgaaca gtgctgttgc cgtagctaat ataaaggctg cgattcgatt
    16501 catgcccgta cgcaatgtag agcgcttggt atttcctaca cttaataatg caatgatccc
    16561 tgcagctggc caatacaaca gcgataagct acccgctgtg accatcgaaa agaagacact
    16621 gatcactgtt ttgactgttc gcattcctat acgcatttac ttcccccttt tttattttaa
    16681 ttatacttga ataatgaaaa actagctatc agacaaaagt ttaggtatga tagtaaaaag
    16741 accaaaaagg agaatctcta tgcaatttgg ccgttttcga ctaggtatgc gtacgatcaa
    16801 aagtgcctta gctgtttttt tatgtatctt gttttttcat ttgactcaac gaggaatccc
    16861 gatgattgct gcattatctg ctgttttttc tttgcgtcag gacttgacta caaccgtttc
    16921 ttttggaaag tctaggatca tcggcaatac attaggtggt acattagcta tcatttattt
    16981 ttttgtcaaa agctattttc acaatgattt tttggtagaa ttgatcttgc ttcctattct
    17041 agttattatt gtgatcgtcg tgtcagatgg tattaacaat aattccggta tcatttccgc
    17101 aatagctacg ttgttgctga ttgcgttgag catccctcaa ggcgaatccg ctttgtatgc
    17161 tatccaacgt gtactagata cttttatagg gacattcatt gcaatcggta tcaatttctt
    17221 tcttcgtcct cctgaaacag aaaagaagga agaactatca gaagatttgg tcgaactcca
    17281 aaagaaagaa cgattgctaa gaacaaattt acaagagata gaagctaaga tccaaaaaca
    17341 aaagaaaaat agcgaggact aattttcttt tgcaataaaa taaaaaaatg gagagaagaa
    17401 ctttaaaaag tcttcctcca tttttgattg aacggtgaag tgtactactt tattcttcct
    17461 tcatcgagtt ttgttctgcc tcttttggcg cttcatacat atttacttgg ctagtagtcc
    17521 cacgtgtcga caaattctct acgatttcct tcaagtcaag tcctgttgtc gcttttagtg
    17581 tttcttgagt agaagaaagc aaatttgtgg cataatttgt cactcggttc gctccactgg
    17641 tttctcctga actgcttcct gtatcgacaa cagagatttt ttcgatattt cctagcggct
    17701 gtgctgcttc gcgcatcaat tgcggtagca tatcgataac catactcaag acagctgctt
    17761 cgccatattc cttgaaggca ttggcgatct tttgttttgc ttcggcttct gcttttcctt
    17821 ttgctagtgc tgcttcggct tctgcttgtc cagctaaacg tgtcttattg gcttccgctt
    17881 ctgccagtgc ttccacacgg aatcgttctg cttcggcttc agtcacttct ttgacttttt
    17941 gagcttgtgc ttcttgttct ttagcgtacc gatcggcatc tgcttttttc ttcacttccg
    18001 aatcatattg cttttcacga cgtgtgattt ctttttcttc cagttcgatt tgtttttgac
    18061 gttctacgat tttaatctgc atttcctgtt cgattacttg ttgttgtgct cgggcacttt
    18121 ctaaattgta ggcttggtct gcttttgctt tagcaacatc ttgttcttgt ttgtaggttg
    18181 ctaatttcag ttctttttct tttaatgatt ctgcgatctc tgtttgtcgc tgtaattcag
    18241 ctgcttgtga ttctttttct gcttgagctt ttttgatacg cgtttctttt agagcttccg
    18301 cttctgctat atctgcatct cttttgactt gggcgattct tggtttccct aaagagtcaa
    18361 gataaccgtt tttgtctctg acctctttga tagtgaaaga aacgatgatc aaccccattt
    18421 ttgcaaggtc tacagaagcg acttcttgta cgctttgact gaacttatcg cgattttgat
    18481 agatttcttc tacagtcata gaaccaagaa tcgagcgcaa gtgtccttct aatacttctc
    18541 ttgcttcatt ttccagttct tctcttgtct tgcctaaaaa ctgttctgct gctgtagcaa
    18601 tctcttctac agatgaaccg attttgatga tcgaagtacc atcacacatc accggtacgc
    18661 cttgttccgt atacacttca ggggtggaga cgtccaattt actcgataat agactgatcc
    18721 gattcgaacg ttgaaaaact ggcaagacga atgcgccacc tccacgcaca attttgattt
    18781 tgttattgct ttcatcaatg tgcacatttt tgcttcctaa ataacttcca ctgatgatca
    18841 acgcttcatc cggttttgct gtctggtact tcgctacaaa gacgatcagc aacatcagta
    18901 aaatcaaagc tgcgattgcg atcgcgataa aaacaactgg tatttccatt taacacacgc
    18961 tcctttaagc ttttatcatg ctttcataag gcatgacata acagattctt tccttgatct
    19021 caatgatcaa tactttcgtt ccccgctcag ctgtctgttc ttgggggctg taaaaacaag
    19081 ctggacgact aatggaaccg gtaacacttt tcaactgaat ttctcccata cctcgtacag
    19141 ggatcggtgt gatcacaaca gctacttgtc cttccagagt tttttcagaa gacgacatcg
    19201 ttgattcggc atgtttcatc ggcatcaata tatagaaatt aagcaaaaat accaacacta
    19261 tcgatatgcc tccactagca ataaataaaa ataaagatga ttgatctgtt aaacgctcac
    19321 ctagaaaacc aaataagctt gtgaaagtta accaagggat aataagcatc ggatcaagcg
    19381 ggccatcaaa atcgaataca tctccaaaaa taatcaatag gactgccaat cctgcacaaa
    19441 tcagcaatgt ataccaataa atcgtctcaa gtgcgattcc ccctatcata tacacgcctc
    19501 cttccatttc tacgtctatc ataccaatgt ttgaaaattc tgtatagctt cttttaccga
    19561 ctcagtggtg ttttttatag gaaggttgtg tttatcgttg acaatttgtt aaatttttgt
    19621 tttcatgtta aaattttcac aataaattct ttcgaggtag cctatgtttc ctttttttaa
    19681 gaaaaaacca ttaaagctcc agaacacgat catccttgtc gtttgtttct ccacattcgt
    19741 ttctttgatt gtttctgcca tattgatcag gaattttatt ctttcgatga accgatctag
    19801 tgtgtcagat aaaatctcta gcattgctaa aatcgttgcc aatgataaac tcatccaaaa
    19861 aaagctgcag actggtgacc cgacacatgc gattcaagga ataacaaatg aaatcatgat
    19921 tgcatcgaat ttagatttta tcgttgtcat ggaccctgaa ggcattcgat attctcacgc
    19981 agacccaagt tacatcggtc ttcctttctc aagtcatgaa gatgtgaaaa aagtgattgg
    20041 aggacaagaa tttttctctg aaaaagaagg aatgttaggg ttcggcttcc gctatttcgt
    20101 ccctatttat tatgatcaag agattattgg tgcagtttgt gttggcttaa caaacaacac
    20161 gattgacaat caagtcaaag atggacaaaa aatgattgtt ttttcattga ttattggact
    20221 tagcgtaggc atcataggcg ccgtttttct tgcccaaaaa atgaaaaaag tactgcttgg
    20281 acttgaacca caagaaatag cagaacagtt aagtgaaaaa acgattatcg aaaatgaagt
    20341 agatgaagga atcttagcca tctcttctga taaaactatc ctcttgatca atacacctgc
    20401 aaaaaacatt ttctaccaaa cagagcagct attggatttc gaagtaggaa aaaaatcagt
    20461 gataatctat atgacgtttt gtttaaagag acgattgagc atcaaacgac cgttcggact
    20521 caatccatgt atttaaatgg gatagaaact atttctagcg ttacacctct ttttagcaat
    20581 gaccgttttt taggagcagt cgcaacttta cgaaatcgat cagaagtaat gaaattaatg
    20641 gaggagcttg gggggacgaa acaatatata aactccatga gagctcaaac ccatgaattc
    20701 atgaataaac ttcatgtcat ttctggtttg attgatttga agaagtatga agaagtcacc
    20761 cattttatcc agcagctaaa tcaaaattat aaaaaagaga ttggccaagt ctcaagtctg
    20821 atcaaagtac ctgcaattgc cggtttttta ttaggcaaaa taaacgaagc caaagaacaa
    20881 tctgttgaaa tgctgttaga aagcgattct tttatcccta aaatggagat ggatgactcc
    20941 atccattcac ttttgcaagt gttagggaac ttacttgata atgcaaaaga agccgtgcta
    21001 caaaaacatg aaagaaacgg acaggtccgg attcatttaa actatgacac agaagctgaa
    21061 gtattcatcg tgaccgtctg cgatgacggt gtcgggatat cagaagaaat ctcagaaaaa
    21121 atatttacgc taggtttttc gacgaaggga atcaatcgtg ggtttggatt gaatctcatc
    21181 cattcaatcg tcaaacgcca cggtggattt ttagaatttt ccaaacaaac aaatggcggt
    21241 acaatcgtct atctagaatt accaaaaaag gaagatcaaa atgatgacaa atgtcctgat
    21301 aatcgaagat gatccaatgg ttgcagaatt gaatcgtact tttgtggaaa gcatccctaa
    21361 tatgaacgta atcgaaagtt tcagaaatgt agaagaagga aaaaaatatt tcagacaaaa
    21421 aaacgcagat ctgctgctgc ttgatgtata catgcctggc gaaagtggta tccatttttt
    21481 atcttggctt agacagcaag gaaatgatat cccagtgatt ttgatcactg ctgcagatga
    21541 tatcgaaacc ataaagaatg tgatccgcta cggtgcctta gattatttga tcaaaccgtt
    21601 cactttgcaa cgttttcagc tggcgatcga aaagtatctt gctttctctc agacaatcca
    21661 aacgactgaa aaagccgatc agaaattgat cgatcaagta ttcaaccaca ccactcccat
    21721 tcacgaaata ccatcattca tcgatttgcc taaaggtctg tcaaaactga ctttaaaaaa
    21781 aataagtgca tttattctaa aagaagatac tattttttca acaaaagaac tggctcaaaa
    21841 aagctcactg tcacgtatat ccgtcaagaa atatttgaat tttttagtag aacaagatat
    21901 attgaacgaa agaatcaaat atttggaaat cggccggccg ctaacctgtt atgaattgac
    21961 aaagaatggg cggaaaaagc tcacagatta ctgttgagtc atcgaattat cccatacaaa
    22021 atagtccaag tatacagaag taacaactgt ttacttggac tatttttaaa cattttattg
    22081 acgaatatcc atgttttctt atcttaattg acgggcttta ggaagagata cctcattttt
    22141 cgtttttcca gtttctatta tttcacgaaa gttctcgaaa cttgtcgaaa tcatatttga
    22201 taatgcctca tctgtatttg aacctacatg cggggttaca agaactctag ggtacatttc
    22261 tactaattgc tggatagcag ggtctggaat cgtctcccat ggcttgaagg atcggaaaaa
    22321 aacctctgtt tcatttgcaa aaacatcggt tgcaaaacca gctaaatgat tgcttttcaa
    22381 agctcttaaa atagcttcat tatcttgaag ctctccacgg gctgtattaa tcaagatgct
    22441 accttttttc atttgagcta aaaatccttc attgatcatt tgatcgtttt cacctgggat
    22501 atgaggtaca tgaatactga caatatcgct tttggctaat aactcttcaa gcgagtggaa
    22561 cgtcaatact tttttagcag cttctgtctg atgaatatcg tagccgatca ctttggctcc
    22621 tagtccctta aacaaaacag cttccgtcaa ccctatcctg cctgttccta tgatccctac
    22681 tgtgcaattt ctgatttcac gactaaacat ttgctcatcc actcgaaaat ctttgaaaga
    22741 tgttcggatc gtcgtatacg cagtatttct caaaagcatc atggcaaaag tcaaagataa
    22801 ctctgctatc gcatttggcg aatacgatgg tacacgggct actgtcatac caaaatcagc
    22861 tgccgcttgt agatcgatat gattgactcc cacagtccgt gtaaaaacat aacgaatccc
    22921 atattcctgc atttttgcaa gattggtctc atctgctata caatttcccc tcaacaatac
    22981 agcatcatgg tcctttgctg acacgatatt gtcatgtgtc aacagttctt cataaagact
    23041 gagatcataa tggtaaatat tcaatttttc aaaaaaatct atctcgttcg gacgaacacc
    23101 gtaacatgcg attctcatac tttcttcctc catttcttat gaaaataaac ctatgccatg
    23161 aatcatttgt aatacaacga tccatacagg tgtcagtacc acagcaaaaa tagttgacag
    23221 taaggatgca ttggaggcta aaagtgcctc cctatcaaaa ctgatagcat aggctgctgc
    23281 cactgttgca gctggtgtag ccatcatgat aacgattgtt gccagtgctt caaaattgac
    23341 tggtagaata ttcgttgccg tcaaaactgc tagaatcacg atattcaatg caggtacaaa
    23401 taccactttg actagactgt aataccatga agttttttca gatgcagctt ttttgaagct
    23461 tacttcacct aatgttgcgc cgattgctag ccacgccaat ggtgaactta aaccagctaa
    23521 ataatccatc ggctgaaata gccacggtgc agtctggtca attcgcaaaa acgctacttg
    23581 gcttatctct ccttctgcac ctgtaactga cacttgtggc agataccctt ggaacagcca
    23641 aatgaaaagg ccggcaaaag tagcgataat gattggattg acgaacatcg ctttgatatt
    23701 tttagcttcc atcttcaagc cactcatttt tatgtatcca taagaataca aaaagattcg
    23761 gtagccaata ttgaaaattg aggaatacat cacgccgaca ggaccataaa tcgcactgac
    23821 gataggcgtt ccgaaaaagg tcgtagaacc aaagatcgtc aggacacgca acgttgtttg
    23881 cttatcccct ttatagctta agaaaaaagg ttttgaaact agaataagaa taatataaat
    23941 aactaatccc caaatcaaga cattgattcc ttgcatcagt aattctgtat tgatatcttg
    24001 catgaaagct cgaaatgcca gtgctggcaa agccactgtt aagacgactt tcgatagaat
    24061 ttttccaaca gattcagaaa aaatcccctt ttttctacaa acaaacccta ataatataat
    24121 aaaaactgtt gaagtgattg cactgacaat cgacatatct gtcaaagtcg atcgaaaaat
    24181 gtcaaataag ttcatctttc tcctcctaat tatgttcatt tattcacaat aaaaaaagct
    24241 tttattttgc taatacgtat taacattttt aattttatct ttacattgtt acttattgaa
    24301 caataggaaa ttaaagaaac ttttgaaact tatgtaaagt gatttttac
//
LOCUS       DADQCX010000039        23441 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.039, whole genome shotgun sequence.
ACCESSION   DADQCX010000039 DADQCX010000000
VERSION     DADQCX010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.039"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..632)
                     /locus_tag="J8R83_001438"
     CDS             complement(51..632)
                     /locus_tag="J8R83_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAZ9574570.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(638..1897)
                     /locus_tag="J8R83_001439"
     CDS             complement(638..1897)
                     /locus_tag="J8R83_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAZ9574571.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1899..2945)
                     /locus_tag="J8R83_001440"
     CDS             complement(1899..2945)
                     /locus_tag="J8R83_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574572.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3180..3455)
                     /locus_tag="J8R83_001441"
     CDS             complement(3180..3455)
                     /locus_tag="J8R83_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAZ9574573.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3698..5008)
                     /locus_tag="J8R83_001442"
     CDS             complement(3698..5008)
                     /locus_tag="J8R83_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAZ9574574.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="J8R83_001443"
     CDS             complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="J8R83_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAZ9574575.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6554..7234)
                     /locus_tag="J8R83_001444"
     CDS             complement(6554..7234)
                     /locus_tag="J8R83_001444"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAZ9574576.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7283..7918)
                     /locus_tag="J8R83_001445"
     CDS             complement(7283..7918)
                     /locus_tag="J8R83_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9574577.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(7984..9387)
                     /locus_tag="J8R83_001446"
     CDS             complement(7984..9387)
                     /locus_tag="J8R83_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAZ9574578.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(9374..10405)
                     /locus_tag="J8R83_001447"
     CDS             complement(9374..10405)
                     /locus_tag="J8R83_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574579.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10436..10657
                     /locus_tag="J8R83_001448"
     CDS             10436..10657
                     /locus_tag="J8R83_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAZ9574580.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10822..11559)
                     /locus_tag="J8R83_001449"
     CDS             complement(10822..11559)
                     /locus_tag="J8R83_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAZ9574581.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11712..13052)
                     /locus_tag="J8R83_001450"
     CDS             complement(11712..13052)
                     /locus_tag="J8R83_001450"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAZ9574582.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13289..14812)
                     /locus_tag="J8R83_001451"
     CDS             complement(13289..14812)
                     /locus_tag="J8R83_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAZ9574583.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15191..15802)
                     /locus_tag="J8R83_001452"
     CDS             complement(15191..15802)
                     /locus_tag="J8R83_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9574584.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15925..16050)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16132..16848)
                     /locus_tag="J8R83_001453"
     CDS             complement(16132..16848)
                     /locus_tag="J8R83_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAZ9574585.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16854..17423)
                     /gene="scpB"
                     /locus_tag="J8R83_001454"
     CDS             complement(16854..17423)
                     /gene="scpB"
                     /locus_tag="J8R83_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAZ9574586.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17407..18204)
                     /locus_tag="J8R83_001455"
     CDS             complement(17407..18204)
                     /locus_tag="J8R83_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAZ9574587.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18174..18545)
                     /locus_tag="J8R83_001456"
     CDS             complement(18174..18545)
                     /locus_tag="J8R83_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAZ9574588.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18564..19451)
                     /gene="xerD"
                     /locus_tag="J8R83_001457"
     CDS             complement(18564..19451)
                     /gene="xerD"
                     /locus_tag="J8R83_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAZ9574589.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19547..20020)
                     /locus_tag="J8R83_001458"
     CDS             complement(19547..20020)
                     /locus_tag="J8R83_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAZ9574590.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20125..20988)
                     /locus_tag="J8R83_001459"
     CDS             complement(20125..20988)
                     /locus_tag="J8R83_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAZ9574591.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21184..23283)
                     /locus_tag="J8R83_001460"
     CDS             complement(21184..23283)
                     /locus_tag="J8R83_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAZ9574592.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT         6409 a         4987 c         3931 g         8114 t
ORIGIN      
        1 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
       61 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
      121 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
      181 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
      241 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
      301 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
      361 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
      421 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
      481 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
      541 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
      601 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
      661 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
      721 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
      781 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
      841 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
      901 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
      961 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     1021 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     1081 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     1141 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     1201 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     1261 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     1321 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     1381 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     1441 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     1501 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     1561 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     1621 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     1681 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     1741 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     1801 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     1861 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     1921 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     1981 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     2041 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     2101 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     2161 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     2221 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     2281 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     2341 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     2401 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     2461 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     2521 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     2581 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     2641 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     2701 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     2761 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     2821 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     2881 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     2941 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     3001 agataagagc aaagctcacc tcataacttg caaataaata aaaattaaat aaaatacatg
     3061 tgttttctat gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc
     3121 taggaaataa aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct
     3181 tatttaacag cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga
     3241 atttcgattt cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact
     3301 tcaaagttac caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata
     3361 gttgaaaata cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa
     3421 gcaacttttt cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga
     3481 gatatgatag aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa
     3541 atattgatta acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg
     3601 tttttaccaa ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt
     3661 tttcttttga aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa
     3721 ttcggatgga cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt
     3781 cataagaaaa atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga
     3841 cagcgacttg tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat
     3901 tgattgctac agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct
     3961 ggttcatact tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg
     4021 cagaaacaaa aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt
     4081 cgaaatcacg cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa
     4141 taattccacg accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc
     4201 cttcttcagc attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac
     4261 gcatcacgct gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg
     4321 tatctatcat taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc
     4381 gggtcgttcc ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca
     4441 aagaggattt accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct
     4501 cttcttcagt ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta
     4561 gtccatggct tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga
     4621 tatcgtttct catttctgga ttatctactt tattgactgc taaaatcact ggtttattac
     4681 ttctgtataa aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga
     4741 ctacacaaat gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat
     4801 ccataaaagg ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac
     4861 ctaaccattc accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa
     4921 tcgagatacg ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc
     4981 caacgattgc aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac
     5041 ttagtttaac gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt
     5101 ttattcctta ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc
     5161 tttcatctca gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct
     5221 tctacttctt ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct
     5281 tctggtaatt cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct
     5341 aaagctttga tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact
     5401 ttcacttcgt caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt
     5461 tgagagatat ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt
     5521 gtcaaacgtt taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct
     5581 gaccaaggtc caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg
     5641 atagacaaca ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct
     5701 acatgactat gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca
     5761 aatgcgccaa aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata
     5821 gttgaaagaa tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat
     5881 aagatcaaac gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct
     5941 ttatagtctg aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca
     6001 cgtacaccga cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg
     6061 accttgccct cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg
     6121 cgttttgaaa gtagatagct gccgttttct ttatctttgc cgatcgtact gataacgact
     6181 aaatctaata catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat
     6241 aattcttttg ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt
     6301 ttgtcttcaa tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg
     6361 cttttcattg cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata
     6421 acacttgtcc tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga
     6481 ttattcaaaa aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat
     6541 tttttttctt aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg
     6601 caacgacttc tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct
     6661 tcagcggaga gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca
     6721 gtgtttcaag atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac
     6781 gctcacttac gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc
     6841 cgatgtctct tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa
     6901 ctaattcttc tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg
     6961 gttgacggat ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt
     7021 gttgcgaaaa agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa
     7081 aagatacatt gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg
     7141 tataaatata attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag
     7201 caggcccgtc gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa
     7261 aagccgcaaa gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa
     7321 agttgtttgg atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct
     7381 cagccacttg ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg
     7441 atgaagaagg tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct
     7501 cacttgagga agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat
     7561 cttgagacac agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg
     7621 actcctcttt tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag
     7681 ttgctgctgt tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa
     7741 tagcgataca taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct
     7801 tttgttgtct ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt
     7861 cccatggttc ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg
     7921 ttttacctcc taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa
     7981 aaatcaatgt tccatgtttt ttttaaataa atttagtaaa atcgtttccc aatgaagttg
     8041 ttcagtctta gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc
     8101 acaacaattc tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct
     8161 gcggcagttt tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt
     8221 ttcctgacgt ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc
     8281 catccatttt ttttgcagct catcaaaggg agcttgcttt gtggcatatt ccaaataaag
     8341 ctcaaaactt tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc
     8401 cccactttga taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat
     8461 ttcttgtaca tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc
     8521 agatttatcg atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt
     8581 tacaaactgc tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc
     8641 aactgtaaaa cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca
     8701 ataaatgatt gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg
     8761 ctgcgttttc cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt
     8821 tggtggtcga tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc
     8881 cgttagtgcc agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata
     8941 ttctggacgg aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa
     9001 cgcaatattt tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact
     9061 caaaaacaaa aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga
     9121 aagtaaacta ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg
     9181 atcttccatt agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc
     9241 cgtcaattga tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc
     9301 tccatcaagc aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa
     9361 atattttttt aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt
     9421 gatacaaacg aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc
     9481 actctcgcac ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc
     9541 actcgtatgg aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc
     9601 ctctttttaa atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct
     9661 gcttggtgat catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt
     9721 gccaaagcga atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt
     9781 gttgcagata aacctctgac tcatcattgt tttttgccag ctgataagga agcagccctg
     9841 ttcgctcatt tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg
     9901 aaaacagctg caccaaactc tcatacgcag tatcaattaa aatttcacgt ggcaattggc
     9961 tttcactaag ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat
    10021 agtcttgaat acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc
    10081 aactagtttc ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat
    10141 gttcggacaa catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga
    10201 tccaaccttg ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg
    10261 gaaaactgtt atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg
    10321 ttcgttttcc cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa
    10381 atagcgataa aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc
    10441 actactatgt aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc
    10501 gccagatatt ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc
    10561 tcatcaacag ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg
    10621 tccagttcga gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg
    10681 tacactaagt tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat
    10741 cccgacttat tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg
    10801 accctatagg acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac
    10861 gatcacagtt tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc
    10921 atagctgcca aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg
    10981 taaatactgc ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt
    11041 gatcgataaa acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc
    11101 catgaagaat acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc
    11161 cattacgcca cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt
    11221 gaccttatcc gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc
    11281 gactgaaaag ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac
    11341 gagagcacca ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc
    11401 aaaaaataag taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga
    11461 tggttcgtac gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat
    11521 gatgactaag ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct
    11581 gagtgacccc tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc
    11641 aaactttcca gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccctttttg
    11701 tatgtttatt tttatttagc acataaacga tacacagctt ctgcataaat ttccattgct
    11761 ttatacatac tacttaattc ccatcgttca ttcgcctggt gcataaagtc aggagtatca
    11821 gggaacatcg caccgaatgc cacacactgg ttcatcgtac gagcaaaagt agcgccgcct
    11881 gatacaaacg gttcagtcat gtctccagta atatcgcgat atgtccccaa tagatttttc
    11941 actaactcac tgtctagtgg cacgtataat gaatcaagga agtcaaattc ttcataagtc
    12001 aacccatatt tttctgctgt tttagttaat ttagctacta aatcatcttt cttgaatgta
    12061 acagggattc tcatatctac accgattttt gtttgttctg gtgtgatttc caaacttgca
    12121 aagttcatcg ttagctcgcc ggattgttca tcttctgttt tgcccacgac agcttcacca
    12181 gttgcatttt cttgaactaa ttttcctaag aaattgattg ggccaaaatc aaatacttct
    12241 gaaagagcaa ttgccagacg agaaatagca ttcactcctt gtgctgcatc tttcgcgtgg
    12301 atacttttac caagaacgac gatgccttca ccttgttctt cgaaatcgaa ttcgtgtttt
    12361 ttcaatgctt cttttacttc agaaagcttt tctccagagt aaggagctgc atcaggaaca
    12421 acattcaacg ctcctccagc ttttacagaa aactcgttcg ttcctggtcc tgtcaagtaa
    12481 gcttgcaata agcctttttc tgcataaatt aaaggaaatt cagcatctgg cgcaaatcct
    12541 tgcgtaattc cttcttcttt ttcgttatat ttttctaaac aacgccataa attttcttca
    12601 tctgtaccaa agataaaacg aatacgtgtc ttgaattcca cgccagcatc aatcaaagct
    12661 ttgacggcat acattgccgc aatagaagga cctttgtcat cttgggatcc gcgaccaact
    12721 aaccagccgt cttttatagt tggatcgaat ggttttgttt cccaattatt ttcgtcccct
    12781 gctggaacaa cgtccatatg acacaagata ccgaataatt catctccaga gccaatctct
    12841 gaataaccgt aatagccttc tggatcttta aatgttctaa atcctagctt ttcactgatt
    12901 tccaatactt tatccaaagc ttcaatcact tttttaccga agggatgtcc ttgtcctgaa
    12961 tctgcttcat ctagtacgga aggaattcgg atcaattcgc tcaatgattc taatgcttgt
    13021 tcatgatgtt gttctgtcac aaattttttc atgatattat cctcctaata tgttaaaaag
    13081 ggtcatgtca aattcctccg acacaacctc ttcttctcaa ataatgacgt tttaagcctg
    13141 ctccatcagc aagcagaatg ttcttaacaa atgatgaaag aaaaaacact cactgaatgg
    13201 agctattgac ttatccacgt gcttatcgat agccgtttat cggtttcttc attcttatga
    13261 tagaccttgt acctgtattt gtctaggttt agaacattgc tgctacacct aggatcacac
    13321 agatggctac aaataatatc gcaattaatt taccggtaaa tttccaccac actgaaacat
    13381 cgaaacgagc aattgctaca gcacccatta cgatagcaga tgttggtgta attaagttta
    13441 ctaaaccaga tgcagattga taagcagtga ttactaaatc cttaccgacg ccggcaaatt
    13501 cacccatagg tcccatgatt cccattgttg cagcagctaa gccggaagtt gaaggaatca
    13561 agaatgacat agggatatag aaaataaatg taataatgat gaatacactt gaagataatg
    13621 aacttaatcc ttgttcgccc caatgtaaga tggtgtctgt gattaatcca ttgttcataa
    13681 ccacttggat accacgagca acagctacta cgattgctac accgatcaaa tcagaagcac
    13741 cagctaaaaa ttcagagaca aattcagact ctttcatgcc ataagtgatt gctactacga
    13801 tggacattac taagaataac atagtaattt ctgggaagta ccagtcacct aatggaagca
    13861 tgcttttacc tagaaccgta cctagtaccg gaaggtttgt taaccagttt gtcaatgatt
    13921 caaaaatcgt gaaattcgca ttcaaggttg tccaaggaat caaactgatg atcatgatac
    13981 caaaagtaat aaagaacaat acattaacat gtttttgttt tttcgtgatt acttcttgac
    14041 gaccgattgc ttcaatatcg aaatgcttca tatcttcttt acgttggttg tatactaatg
    14101 attttgttgg atctttttcg atctttgatg cataacgata cacatataca atagaaatag
    14161 ctaacaaaat aacgaacatc aagaatcgaa gaccaatacc ttcacccatc gaaatcccaa
    14221 cagcttgtga agctacgcct gttgcaaaag gatttaccgt tgaagctaga cagcctactt
    14281 gagaccctac taatacgatt gctacagcta ctactgtatc aaagcctaca gccatcatga
    14341 ctgggatcag taaagcatag aatggaatcg tttcttctgc cattccgtaa gtagagccgc
    14401 ctaatgcaaa taacagcatc aatactggaa taagcatttt ttcttttcct ttgaatttct
    14461 tcacaactga agcaatcccg gcatctagtg cccctgtttt gttgataata cctaaaaatc
    14521 caccaacaac caaaatgaag aaagagattg ggattgcagc aggtgtttct ttagttagct
    14581 cccccgctgg tacacctagc atcccattga ttggcgccat gaaaatatcc cacagccctt
    14641 gaggattttg ttgtactcgt tcatatgatc cagcgacgat gttgcctgca tcgtctacac
    14701 tatagtgccc agctggtata aaccaagtaa gtacagcgat tactgcaata ataataaata
    14761 agaccgtata cgctgaaggc atttgaaatt ttttcttttt tgtttgttcc atcttcttct
    14821 tcctttcttt tccgttagag acaacaattt tggctctaat gttattttat caaaaagagt
    14881 atcagaacaa aaataataac acgcattttg taaaactttt gttcaaaaag ttcgtttttc
    14941 cctattccct cctctttttt caggttttta aagctttctt ctttttcatt gtagcgtttc
    15001 ctttttttta taaacaaaca ttttcgtctt ttaaaaggag aagaatttca catttgcaaa
    15061 gaattgattg atttttatgc ataaatcaaa aaaatactca aaacaaacaa ataaaacgtt
    15121 tacattattg catgtcttgt atttttttcc aaaaaaaaaa gaccaagaaa tttcttgatc
    15181 tttttgatat ttatttgact gctgtatgac gttgttcgaa ctgatgttgt tttcgactta
    15241 accatggaag aagttgcgca tgcagcacta aaaagacagc actcacgatg aatcctttga
    15301 tcaagttgaa aggaacgatc ccaatcagta catagtttgc taaagacatg cccagcatct
    15361 gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt aataacgaaa taatttgcga
    15421 tactcataaa aatagttaga gcgatggttc ctgtaatgac acctaaaaat ttgtttcttc
    15481 ctttatgctg tttctttaca ctaaagaaat aataaatcgg gaatgtaaag atcgttgttg
    15541 ataagaaact agcagtgtct cctaccaaat tatccggaga aaaacctgta gtcagcagat
    15601 gtaatactga acgcaagaac gctgttgcaa ctccggccgc tggaccgaat aagaacatgc
    15661 tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa actaaaagcc ggcatgatcg
    15721 gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa catcgctact gcaaccattt
    15781 tctgtacacg ggtgttcttc atttgaaatc ctcctgttag gactcctctt cagcgaactt
    15841 tttgacgttt ctctccaaat gaaaaaactc tattttccag ggaaaataga gttagagtta
    15901 tttgatcaag cgtcgtcaaa taagctctat cttctttatc cagactatac tgtcggtatc
    15961 ggaatttcac cgattcagct atttttttgc aaaataggtc gtggactata accaccggtc
    16021 gggaatttca ccctgcccct gaagacgaac cttatataat ttttgtttac atattcatta
    16081 tacatatcta ttcaaaaaac gcaacatcta acacttataa aaagtaagtg ttcattttga
    16141 gtggttcagc aaactgctga cttctttttt gttcagttca cggtaatccc caggacgtag
    16201 gccttgtaaa gtcagatctc cgtatttttc acgttttagt ttttgcacag gaagaccaac
    16261 tgcttgaagc atatttttca cttgatgatt acgtccttcg tggatcgtca attccacgat
    16321 actgtggttt gtcttaggat ccactgataa aatttggaat ttagctggag atgtttttcg
    16381 tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc gattttgtag cgatcccttt
    16441 tacctttgca acgtaaactt tatccacttc atgttttgga tgtgtcaggc gctgagcaaa
    16501 atctccatca tttgtcagta gcaagatccc cgaagtatcg taatccagtc gacctacagg
    16561 atagatacgt tcttttacca tcggcaaaag atccgtaaca acttttcttc ctttgtcatc
    16621 tgcaacagca gaaataactc ctttaggttt gtacaataaa tagtaaccgt attcttcttg
    16681 ataaattggg acttcatcca cttccacagt gtcatgtttc ccaactttta tccctaattc
    16741 ccttacaact tgtccgttta cttttacacg tcctgcaagg atgaattctt ctgcttttcg
    16801 acgagaagtg atgccagcgt gggcaattac tttctgcaat ctctccatta caattattct
    16861 cctttattca ttccatcaaa gaatagatct ggtgacacgt cttcttcaag tgaaatttcc
    16921 atttcttgtg tatcaggcag ttcttctaat gatttcaaac caaaataatc taagaagtag
    16981 ccagttgttc catataatat cggccgacct ggtccttcta ctctaccttt ttcttcaatc
    17041 agtttatggg cagctagacg ctgtaccgct cctgaaacct gaactcctcg aatctgctcg
    17101 atttcagctc ttgtgattgg ctgtttataa gcgatgattg ctaaggtttc gacggcggct
    17161 tgagataatg tgtttgatgt cccttgcgca tatcgcttaa gtaagggagc cagctctttt
    17221 ttagtcgtta atacataatg gctttccgtt tcaaaaatat gcaaagctga gtgcgagttt
    17281 tgagtgtaag attcttttaa ttctttcact aaacttgtga cttctgcttc gctgagattt
    17341 aacagtccgc ttaattcttc attactgatc ccttcctcgc caacaataaa aagaagggct
    17401 tcaagttcac ttaatttcgt catgttcggt atctcctact gctggataaa gcataattga
    17461 ttcatagttt tctttttgtt gcgcaatgat ctgccctttt ttcatcaatt ctagcaaagc
    17521 cataaaagta gtgacaactt cacttttaga aggtgactca aaaaaagaat cgaaagtaca
    17581 gccatgcgca tttcttttta tacgctcttc gataaatacc attcgttctt cgatcgttgt
    17641 gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat ttcttacgtt ctaagatttt
    17701 ctgcatggca cggatcaaat cgattttttt gacttgtcct cgcttcaacg gcttttcagc
    17761 atccgctaac ccatcgatgt tcataggttc ttttgtgtaa taaagacttc gttcctctgc
    17821 tttttctgtc agtctttcag ctgcatattt atatttacgg tattctaaaa gctgagtgac
    17881 caattcttct cgaggatctt cttcccataa ttcttcatcg tctgtgacga attcttggac
    17941 aggaagcaat gtcttgcttt tgattgccat caatgtagca gccatcacta agtattctcc
    18001 tgcaacagct agctcgagtg ttttcattgt atggatataa ttcatatatt gctccgtgat
    18061 cgtagcgatc ggtatatcat atatatcgat ttccatttgc tgaatcagat gaagcagcag
    18121 atcgagagga ccctcgaata catctaattt aatattgatc tccgtcaact cattcactct
    18181 ttcttctttt tctttgctag ccattttcca atgtaaggct ctgtgatttc agttgcacgg
    18241 atggagacat ccgggtactt ttcctgtaat tcatctaaca tttgaaagcc catattctca
    18301 ccgcgataag acggattcaa agaaatgtca tggatgatca gctgatcgtt cgttgcccag
    18361 taaataccaa taatcccttg aatgttggtt gaaccttctg gcgtaaagaa aaaaagttca
    18421 taatcgtctt cagattcgta cgtatcaatc tccttcaaca aagaagtttt acctgtcagt
    18481 ttcttatgga aactcaatag tcccatagca attttacggt tttctttccg gtaatgtgtt
    18541 aacatcttct caccttccta tgactaagcc cttggaaaat gctgcttata aacatccgtc
    18601 attcttttct tcgtgatatg tgtataaatc tgagtcgtag agatatccgc gtgacctaac
    18661 aattcctgta ctgtccgcaa atcagctcca ttttctagca gatgtgtggc aaagctatgc
    18721 cgcagcgtat gtggtgttac ttctttgtaa atcccagcct ctcgtactaa ctgcttcaga
    18781 tttttccaga ttccttgccg agaaagacct ttcccatgat tattgacaaa tacatgcatt
    18841 tcagatgcgt cctttacaag taatggacgt gcttcgtcta agtagcgttc cagccattgg
    18901 atcgcataat cacctaaagg aatgatccgc tctttatctc cttttccaac tgtctgtacc
    18961 agtccaagag aaagatgaag atctcccaat ttcaatccaa tcaattcact gacgcgcatc
    19021 ccagtagcat acatgacttc caagattgca cgatctctta tccctaacgt ttttgtcgta
    19081 tcaggtgctt caatcagctt ttctacttct gtcagagtca atgtacttgg taatttctgt
    19141 gctttcttcg gcgtatcgat atgttgcatc ggatcatgat cagtgatacg ctcttgccgt
    19201 aaaaactgat ggaatcttct gagacttgag atcatccgag taacagttgc tgtcgctttt
    19261 ttttcttcat gcaacttctc cagaaaacgg atgactaaaa agcgatcgac atcctgccat
    19321 gaagcaattt tctgctcctg tagaaaatgc aagtactgtt ccaaatcacg ttcatagctt
    19381 tgtcgtgtat tggcggacaa tccccgttca atattcaagt agtggagata atcgttgatt
    19441 tgctctttca taataatccc cctcatgcct ctctatcata tcagataccg cttcattctg
    19501 atagtctttt tccataatct gagcaaagaa aaagccgtct agacactcag acggactggt
    19561 ttcttttttc tttttcatag cattcctgac agattccatg gaacgttagc cgatgatctt
    19621 ttactaaaaa atgataacgt tcttctacta cttgctccac ttcaagtaaa agatcctctt
    19681 ctacttcctc gatcgtgccg cagttcaagc atagtaaatg atgatggaaa tgtttggcgc
    19741 cttcttttct caaatcataa cgggctaatc catcattaaa acttacttta tcgacaattt
    19801 tcaattctgt caagatttca agggttcgat aaacagtagc aagtccaatt tccggactct
    19861 tttttttcac taaaaagaag atttcttctg cagataaatg ctctttctca ttttccaaaa
    19921 gcacaagcag agtagcttct ctttgcggtg tcagcttaaa ccccgcttca tgtagctgct
    19981 gttttgtttt tttcatcgcc gaaatagcat tcatgaccat ttactcaacc ccaacaattt
    20041 ataataatta caaataaaaa aagatataac actatgttaa ttaaaattat tataagctag
    20101 ttaagaaaaa catgcaaggg attctcaatt agattttttg actagttttg tcacaccgtt
    20161 ttcttgtgta atcaatcctt gtttcaaaag attacctaat gcgcgcttaa atgctccttt
    20221 gctgatacca aaagctttca tgatttcttc tggatccgat ttatctgtaa agttgatttg
    20281 ctgatctgca gaacgttcta aaatggttaa aatcatttgt gcatcatctg atatagcttc
    20341 atatgctctt ggcttcaatg aaagattcag tacaccgtct ggtcggacac caatcactcg
    20401 accttttatc tgctcgccta gacgaggttc attatatcgt tcagaaggat ggataaaccc
    20461 aagatagaaa tcttccgtta aaacgtacgt acctgttaat ttcaagcggt atgctgttcc
    20521 tatcacatct ttgtttttca tttcttctgt tccatatttg cttaaagatt tgaatatttt
    20581 ttcatctgct aaactgcccc aaatacggtc ttttgcatca actctaaggg aaatcatcaa
    20641 gcgatcccct tttttaggcc atagctctgt cattgtcggc aattcatcaa gagatacgac
    20701 aaagtcttta tctggaagac cgatatcgac aaacgcacct aaatcttttc gtgtagcagt
    20761 aacgattcca aaagcgtaat gaccgatacg gcttttagga atttgtgtag tgatccgatt
    20821 ttcatgtttt tgattttggt aaccgaatcc ttcaactgct tcaccgattt tgtgttcacc
    20881 ttctgatttg cttaagccaa aggtttgtcc gtttttttgg acaaagtagt ttttttcatt
    20941 ttcatcaata ataatacctg taaatatagt tgctaataaa tcgttcattt ttttctccct
    21001 ctatagtgaa aggttttctt aatacatttc tttgctatca taacataatg ttatctactt
    21061 gaatagctga gccttggttt ggaaaggtga aaaaaggagt atgacaacag ttgtgtcata
    21121 ctcccctttt tcgaataaac ggtgttaaac ggcaggctca cagcctcttt catttgccta
    21181 aaattaattg ctcccatttc ctccgaacca tccagtttta cagttgatgg ttacgatgta
    21241 aaatggcaaa gcactttctc caatgccttt catcaatgca gattttgttg aagtggcata
    21301 tagattataa tagccttccc cattttcgat tctggctttt tctaatctgt aacctccttc
    21361 aacgatatat ccacgttgga tacatgtagc aatcactttg ctttggacac ctggtgccca
    21421 cgtccatgct ggattagatg catcggcaat atcacttgct ctggcagatt tgattggctg
    21481 attcgctgag tttgaagagg aaggggtcga ggatgccgct tcttgctgtg ctgcttgtgc
    21541 gaccgcagct tgttgagcgg cttgagctgc agctgctgct tgagcggctt gttttgcttg
    21601 ttcttcagct gcttttttcg cttcttctgc ttttttcttt tcctcttctt cttttttctc
    21661 tttatcagtg agcatcttat ctacttgttt caattgttca ttcaactgag cagatagatc
    21721 tgtatttttc actttttcta ctgcttcttt tgccgtcttg tattggtcgc gtgttgctga
    21781 atccactact tttccgtctt taaagactat agctgttttt tctttagctg tttgcaattc
    21841 agcatattga tttttagctt ctgtttgtgc ttgttgaatc aattttccaa aatctgtgtt
    21901 atccgtttcg attgcttgga tctctttatc tgctttcaac ttgatgtcat ctgctagatg
    21961 atcatcgacg atggcaggtg ctatgaacca ctcattcact ttttggatat ctcggatctt
    22021 agattggata tcttggtaag ttgtttctaa ctctgaatat cctttttcat tcttaagact
    22081 ggataaatca ttttttagtt ttgataaatc ttgatgaatc atatctgcac gaataaattg
    22141 atggtgatca tctgtataaa aggcagcaag tttctcatga agttcttcca tttgttgctg
    22201 tctttttgct tctgctgcta cttcggcttc tactttttga tgatggtcat aataagccca
    22261 gcttcctcca ccgagtagaa gtactgctgc taaaacgaga taaggtactt tttttgattt
    22321 tttcttttgc gctttatctg gatctgtttt ttctaagttt gattcttgat gtgttttttc
    22381 agtatctggc acgattgtta ttgatttcgc ttctgcttca aacagcttag gctggttctc
    22441 ttctttttct atttttgctt caagatcagt accctctttg cttacagatt gattttcagc
    22501 atcggattca ctatttattt catcgggctc tgttgacttt ttgtctgtgt tttcgagtat
    22561 ttcttttttc tctgcttccg gcagtttatt cgttttttcc ttttctaatt gtttttcagt
    22621 aaatacttca gttttttctg tgatatccgt ttttacgtct tttattttta ctgtttcttt
    22681 acctgtggcg ttttctctat cagagtcttt ttcagtttct tgttcctttt ctggctctac
    22741 tttgttttcc tgtgcaattt tttcactgat cattttgagc agctctttcg cgtgctcttc
    22801 ttttgtatct tcacgatgtg ctttgatata agcggatagt atcgaatttt cttcctcatt
    22861 atcgacgatt tctttcagtt cagctactct tcttttttgt tttgattcaa gcgtttcttc
    22921 ttgattcttt cctgattctt ccgaagtctc atgaacagtt gctttcttct gttcattttt
    22981 ctctatatta gttacttgat cgtgagcagg tggttcttcg tcttctggtt ctgctttttc
    23041 gaataattcc attacagatt ctagaggtaa atctttcaat tccgaccatt cgattggatc
    23101 gtttaattct gtatcaggaa agactgcatc ttcagttgat ttatcctgca tagctgcatc
    23161 tgtatttgtt tcttcaattg attcttttat ttgctgatct tctgcagtta tttgatgacc
    23221 gcagtctgga cagatagtat tctgctccat ttttttcgat ccgcaatttg gacatttttt
    23281 catcacttag cgatcggctc ctttactagg tttacgctac catttaatct atcatattct
    23341 atacgtcacg ccaatagctt atttttagga tttacttaaa aataatgaat gaatttcctt
    23401 cctatagaaa aaaaagcttg agactgcgta gtctcaagct t
//
LOCUS       DADQCX010000040        22859 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.040, whole genome shotgun sequence.
ACCESSION   DADQCX010000040 DADQCX010000000
VERSION     DADQCX010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.040"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(153..551)
                     /locus_tag="J8R83_001461"
     CDS             complement(153..551)
                     /locus_tag="J8R83_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAZ9574593.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="J8R83_001462"
     CDS             complement(548..1321)
                     /locus_tag="J8R83_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAZ9574594.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="J8R83_001463"
     CDS             complement(1318..2001)
                     /locus_tag="J8R83_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAZ9574595.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="J8R83_001464"
     CDS             complement(2168..3055)
                     /locus_tag="J8R83_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574596.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="J8R83_001465"
     CDS             complement(3052..3921)
                     /locus_tag="J8R83_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574597.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="J8R83_001466"
     CDS             complement(4058..5344)
                     /locus_tag="J8R83_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9574598.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="J8R83_001467"
     CDS             5617..6195
                     /locus_tag="J8R83_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9574599.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPMKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="J8R83_001468"
     CDS             6195..7124
                     /locus_tag="J8R83_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574600.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="J8R83_001469"
     CDS             7121..8857
                     /locus_tag="J8R83_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9574601.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="J8R83_001470"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="J8R83_001470"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAZ9574602.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="J8R83_001471"
     CDS             complement(9753..10262)
                     /locus_tag="J8R83_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAZ9574603.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="J8R83_001472"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="J8R83_001472"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAZ9574604.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="J8R83_001473"
     CDS             complement(11563..12654)
                     /locus_tag="J8R83_001473"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAZ9574605.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="J8R83_001474"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="J8R83_001474"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAZ9574606.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="J8R83_001475"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="J8R83_001475"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAZ9574607.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="J8R83_001476"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="J8R83_001476"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAZ9574608.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="J8R83_001477"
     CDS             complement(16617..17591)
                     /locus_tag="J8R83_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAZ9574609.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="J8R83_001478"
     CDS             complement(17572..19455)
                     /locus_tag="J8R83_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAZ9574610.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="J8R83_001479"
     CDS             complement(19473..21698)
                     /locus_tag="J8R83_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAZ9574611.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="J8R83_001480"
     CDS             21813..22847
                     /locus_tag="J8R83_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9574612.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
BASE COUNT         6560 a         4979 c         4120 g         7200 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atgcaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg atgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctttct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgt
//
LOCUS       DADQCX010000041        22640 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.041, whole genome shotgun sequence.
ACCESSION   DADQCX010000041 DADQCX010000000
VERSION     DADQCX010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.041"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..505)
                     /locus_tag="J8R83_001481"
     CDS             complement(<1..505)
                     /locus_tag="J8R83_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAZ9574613.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLF"
     gene            complement(507..1271)
                     /locus_tag="J8R83_001482"
     CDS             complement(507..1271)
                     /locus_tag="J8R83_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAZ9574614.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1279..1956)
                     /locus_tag="J8R83_001483"
     CDS             complement(1279..1956)
                     /locus_tag="J8R83_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAZ9574615.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(1993..3378)
                     /locus_tag="J8R83_001484"
     CDS             complement(1993..3378)
                     /locus_tag="J8R83_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAZ9574616.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3588..3672)
                     /gene="ffs"
                     /locus_tag="J8R83_001485"
     ncRNA           complement(3588..3672)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="J8R83_001485"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3695..4210)
                     /gene="tadA"
                     /locus_tag="J8R83_001486"
     CDS             complement(3695..4210)
                     /gene="tadA"
                     /locus_tag="J8R83_001486"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAZ9574617.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4317..5174
                     /locus_tag="J8R83_001487"
     CDS             4317..5174
                     /locus_tag="J8R83_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAZ9574618.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5255..5590)
                     /locus_tag="J8R83_001488"
     CDS             complement(5255..5590)
                     /locus_tag="J8R83_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574619.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5657..7027)
                     /locus_tag="J8R83_001489"
     CDS             complement(5657..7027)
                     /locus_tag="J8R83_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAZ9574620.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7105..7641)
                     /locus_tag="J8R83_001490"
     CDS             complement(7105..7641)
                     /locus_tag="J8R83_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574621.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            7950..9431
                     /locus_tag="J8R83_001491"
     CDS             7950..9431
                     /locus_tag="J8R83_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9574622.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(9534..10241)
                     /locus_tag="J8R83_001492"
     CDS             complement(9534..10241)
                     /locus_tag="J8R83_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAZ9574623.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(10320..10658)
                     /locus_tag="J8R83_001493"
     CDS             complement(10320..10658)
                     /locus_tag="J8R83_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAZ9574624.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(10769..11731)
                     /locus_tag="J8R83_001494"
     CDS             complement(10769..11731)
                     /locus_tag="J8R83_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAZ9574625.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKINVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(11746..13077)
                     /locus_tag="J8R83_001495"
     CDS             complement(11746..13077)
                     /locus_tag="J8R83_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9574626.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(13085..13765)
                     /locus_tag="J8R83_001496"
     CDS             complement(13085..13765)
                     /locus_tag="J8R83_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAZ9574627.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(13984..14463)
                     /locus_tag="J8R83_001497"
     CDS             complement(13984..14463)
                     /locus_tag="J8R83_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAZ9574628.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(14590..16269)
                     /locus_tag="J8R83_001498"
     CDS             complement(14590..16269)
                     /locus_tag="J8R83_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAZ9574629.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            16817..18319
                     /locus_tag="J8R83_001499"
     CDS             16817..18319
                     /locus_tag="J8R83_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574630.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            18332..18994
                     /locus_tag="J8R83_001500"
     CDS             18332..18994
                     /locus_tag="J8R83_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574631.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(19095..19298)
                     /locus_tag="J8R83_001501"
     CDS             complement(19095..19298)
                     /locus_tag="J8R83_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAZ9574632.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(19409..20593)
                     /gene="iadA"
                     /locus_tag="J8R83_001502"
     CDS             complement(19409..20593)
                     /gene="iadA"
                     /locus_tag="J8R83_001502"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAZ9574633.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(20750..22489)
                     /gene="yfcC"
                     /locus_tag="J8R83_001503"
     CDS             complement(20750..22489)
                     /gene="yfcC"
                     /locus_tag="J8R83_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAZ9574634.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT         6623 a         4841 c         3804 g         7372 t
ORIGIN      
        1 cgaataacca gtcatcgttg ttgaaaaacg tttcatgaaa aaggataaaa aagcgatcaa
       61 atcctatcat catgaaaaaa ccgaaaacaa ctggcagtaa catgccgatt tgaaacggac
      121 gaatcaaccg ccaaagccga tcattctttt gcaaatattt gataaacaaa atactcggga
      181 tcaaagtgat gaaaaacaca gcataatcca ctaaaaacaa aattttcact tcataaaagt
      241 gatgggctcc gctagcagaa actgggaaat ctggcaagct gaggatggtt ttgaagggat
      301 tattgagata attcattagg tgatcaaaat ttttcagtaa cgtctcttga tctaaagaag
      361 tataatccaa aatttgcaaa tgtccgatat caaatacgta tagtggtcga aagttgatcg
      421 tcacaccaac tgccagactg atcagtgtca gaaataggct gaacaatcca gcatattcca
      481 tccactgcca tctcgaattt ttcatattag aagctccatt catccagtga ttgtttcaca
      541 taggtagctg ggataggcaa cccaggtaca tcttcttctt ttgtaaaacc tgataaaacg
      601 agcaaagtat ctatattatt gcgtatccca gcttggatat ctgtttcata gttatctcca
      661 accatgatta cttcttcttt ttgcagccct aatacttcaa cggctttatc cataatgatg
      721 gcttctggtt ttccgatgta gatcggcggc gtttgggttg ctgtctctac aaaagagatg
      781 actgaccctg ctccaggaag aaggccgcgt tcagtaggta tattcttatc tgggttcgtt
      841 ccaatgaaag tagcaccttt ttgaatagca agtgttgctt taactacttt ttcataggtc
      901 agataattat ctaagcctac cactacatag tcaggagcct cttcttccca tgtaaatccg
      961 gcagctaaaa tcaagtcaat caatcctgct tctccgataa catagacttt tttccctttt
     1021 ccatctgctt tcataaaatc gattgttgcc aaagtagctg tgtagactgt ctctggagct
     1081 acatgaatgt caaactcatc tgctagacga ttagctactg tttctggtga cttagtcgtg
     1141 ttattggtaa caaacaagaa aggtaatttt cttttttgca attcttccac aaatcgttta
     1201 ccggccggta tgggttgtgt cccacgataa atcgttccgt ctaaatcaat taaatatcct
     1261 ttatagtcca ttcatccact actcttccct ttttctgatc gtaaatgctg tttttgtttt
     1321 ttctacttgt ttaggttgtt cttgtttttt tactttttca gaggtttttg ctgactctgt
     1381 ttttcgattt ttaataaccg gttttttgcg attagatgcg actggtcctt ttttctcatc
     1441 gatatacgca cgattatggt tttttttctt ttttcggcgc tgagttgtct tttctttttt
     1501 accgccgatt ctctcgatga caaaatacgc acaaccaaaa ttgcaatatt cgtaaagata
     1561 gtcttccaag gaatcgattc gctgatctgg atgcgcccgt cgattatccg cttggaaaaa
     1621 tccttttagg cgtagttgtt cataacccca atctcctacg atataatcat atcgggctag
     1681 tacatcactg taacgttctc caagcttttc tgcattaaat ccttcacgat aatcggacac
     1741 aagccgataa tgtctttcac ctatcaaaaa attactgtca tctaacagtg tcactagctc
     1801 gcctttgact ttttctgctt taggctcctc aacgatttct tccaaagcag ctgtcagttc
     1861 ttcggtgact gttgtttcct gttcagctga tgattttttc ttagcaattt ctgttttatg
     1921 ctcaacgttc tgctgttcat tttgttttgc agacatgcgt tcaccaccta tcttttttat
     1981 tataccttgt ttttatttga ttgggtagtg agctttcaag taatctccta ccacacttcg
     2041 gataaattca gggaacaaaa attcattttt tccagcaatc tcaatcgttg gaaaaaatgg
     2101 aacaaacatc aaatgatcta cggtagtaaa agtataattt ttattcagat cgattggctt
     2161 gttcttccaa aagacttgat ggttaataga atcatatgtg attccattat agaccatctg
     2221 cccaaaaatc ttaccgcgaa atcccattcc cttcatagga tagttacgta aaaagttacg
     2281 atttttttct atttctaaaa ctaagcggat cagatcattt ccacccaatg tgacatttaa
     2341 caagtgcatc ggatgcggca acgcagtgtg aagctgatcc tgattgaccc gcccttttgg
     2401 aatttcagtt aaaaacagac cactgtttaa tattgctgct tccgtctttc ctcgttcttt
     2461 caccgcctca aaggctactt ggataaacga atgctcattg aagatatcta gactcagaga
     2521 aaatggcaaa tctgctactt ctttttcttt taataattca tgcccacgtt ctagataact
     2581 atttatttct tgttcatctt ctgtaaaagc tgtcattgtt tcggtaggga tggctttggc
     2641 tgaatgctta aggatttttt tctcttcatc gatggttaaa tggacttcac cgacatactg
     2701 cccgtacttt ccagcggctg ctatttggac atcattgatt acgtgacctt ctctgaataa
     2761 atgatgggtg tgcgatccta aaataacatc aattgctggt atttcttttg caatttggaa
     2821 atcatcctga atcccgagat gactcatcaa aactaaaaca tccacttgtg aacgtaaatc
     2881 ttcgactaat tctggcaaaa tatcataagg attccgtatg tcccagccat tcggattata
     2941 agtaagcgga aatggagcag taaatgcaat tagtccgatt ttcgtctggt gtttcgttgt
     3001 aatgatttta tatggtttcg tccatgccgg tggctggagc gtatttttat cgaataagtt
     3061 atccaggatg atatcaaact cagcatgatc gtataaatga ttcaactctt ctttggaatt
     3121 tcctacgcct tcattgtttc ctatcgtcgc tgcatcataa ccaacttcat tcatcagcaa
     3181 gatattttcc tgtccattcg ttgcttctga caatggatgc caacgatcca caaaatcacc
     3241 tagatctact gcaatcgttg tcgttttttc tttcttttcg ttttctcgtt tacgttgatc
     3301 caaaaacctt ctgatccttg gccaattttc taaatgagaa tgcagatcat tcgtatgtaa
     3361 aatcactatt ttttccatgt accctctcgc ctctctttat ctttatcata ccataggcag
     3421 ctttttcttc cattgaaaca agctctattt cagagttttt cctgccttga agcaaattgt
     3481 ataagtacaa tattcgataa atcagtctgg ctaaaaaatc aggaacattc atttttacag
     3541 tactataaaa ataaaaaaaa cagacccgaa agtctgttgt cgtttcatta taatcagaca
     3601 catggcggaa cctgcttagt gctgcttcct tccagacctg acacgcttca caagcccacc
     3661 attgtcctag cctttcggca aagaatagta taccttattt ttcattcgtt gaccagtctt
     3721 tttttaattt cttttttcgc tggcggagct ttcggaaaaa gtcagtcaaa atcatcccac
     3781 attcgtcttc taaaatgcca ccttctacat atgcttggtg gttaaaccgc tcgtcctcca
     3841 aaagattcat caaggtaccg gctgttccgc cttttggatc atacgcgccg aaataaactt
     3901 ctgctacacg agacaaaatc atcgcgccgc tgcacatagg acaaggctct aaggtaacaa
     3961 aaagtgcagc atcttccaag cgccagcttc ccactttttc acaggcttcc ttgattgcaa
     4021 gcatttctgc atgtgtagta gcatcttgcg tggtttctct aaggttatat cctcttccaa
     4081 tcacttttcc atccaataca accactgctc caatcggaac ttcatgaagc atttctgctt
     4141 tctttgcttc tgccaatgca aggcgcatcc atttttcttt ttctactgca tcaagatttg
     4201 tatttaccaa ttacccttcc ctgcctttgt tttttcttgt tttactttag catatgataa
     4261 aaaggctgta actaactttt ttttctatgg taaaataaat acaagaggtg aacaagatga
     4321 aaatggataa attacttgct ctttacccac aagcacagaa aaaaaactct ccagcatcag
     4381 aagcggatat cctttctttt gcaattgatg atgcttttat ctggatcaaa caagattcat
     4441 tatctcaaca agaaaccagc cttttgaaag cgttattccc tgtaatcaac gatcaaaaaa
     4501 aacacccatg gtatcactat ctttttaaag atgcttcttg tgttcaagaa aaaagctttc
     4561 gtttgatcca gcttcacgtc gaatcaaaag gagaattctt aaaaaaagaa tggcaagata
     4621 ctattttgga attatttcgc tattctgctg atttcttttt ttatacagac acagatgcgc
     4681 tcttagtcga acaaataaac cgtgattatc ttgatgctac tgaaatcaac ggtatttttc
     4741 tatctttaga tgctgatttt gatacgacaa cgtctgtatt cgttggttct ttccattcac
     4801 ctggcaccga cctcgtccct ttgtttgctg aagaaagaaa aattttttta acagagcaaa
     4861 acaatcttta tactcacagc cgtacttttt ctatgcaaga tgtggcttta cattactata
     4921 caaaagatac tgtaaaagat agtaagttga tcaaaagtta catagaactg atcaaacaaa
     4981 atgaaatgga agtgatcatt caagaattat ggaatgaatt aggcaatgtc agctctgctg
     5041 caaaaacact gtttcttcat cgtaatactc taaaatatcg aatcgaaaaa tttcaagaac
     5101 agtctggttt caatctaaaa aaagccaacg atttactgtt ttgctatctt ttattgcttc
     5161 atgaacataa ttaaagatag attaaagggg ttgtgacaat aattttgtca caacccctta
     5221 tttcgaatga atagtgttca aaagctagtt tctcttacat cattttttca acaaaatgca
     5281 ttagccggtc ttttacatct tcggttgaat ctttgattga atcaccataa acagagattt
     5341 tcttttttcc tgatttgatt tttgctaaca ttcccatcaa agaatccaag tcactatctg
     5401 aaagaccatc tacgatttct agtaattttt catttccatc aaatttgtca tagacgaatt
     5461 tttttacttt cgtccgagta gtcatatgat ggatcttttc cattactttt cccgatacaa
     5521 cgactgctgt cgctacactg gcagcggctg ctacgcttaa tccgattgtt acttttgttg
     5581 atgttttcat aagtatcagc tcctttttat ctatctccat catagcatag acaaaaaaat
     5641 aaacgaacta atccactcag tgaaatctca atcctttagg gaaaaagttc tttactgttc
     5701 cttttacttg tttcccaaat ccgacaggta tcttatctaa tactagcaaa acccatcctt
     5761 gattcccatc acgttgaaat gtttctcctg ctgtgtaaga ttgccattcc ttttgagtga
     5821 tcggcaagca aggtatattc tctatctttt ttgtagcaag cgctaatgca tagctaggtt
     5881 caaatcgatt ctttttgaaa tctcctaaat gcaaacctgt acgtacgact tttaaaccat
     5941 cgagagaagg ggctaactca ggaacttccc aaagatggtc gttgaacact aaaagtcttc
     6001 cagtagcttc ataatgaaaa tcatttgaaa actccgtcca gagtttttcc tgctcttttg
     6061 tcatttgcac tttacttttt tttcgtgtct tcttttcttt atgcatctga ttttgtccat
     6121 gaaaagtcag ctttgcaaca aaatgtcctt caccctgatc tttatgaggc catatacgta
     6181 ttgttttttc caaaccagct acgcttcccc attcagaacg tcctgaacta acggattgag
     6241 tcaaaggaat ctcctcaatc gttactggat aattttctac aagccagcta atgatctctt
     6301 cattttcttc tggtgcaaac gtacaagtcg aataaatcag ttgtccttta ttttttagca
     6361 tttttattgc tgaagacaaa atctcttgct gacgtttttg acagtatagc ggagattctt
     6421 ctgtccactc ttttattgca tttggatctt ttcggaacat tccttctcct gaacaaggag
     6481 catcaaccac gatccgatca aaaaagcccg aaaaatgagg gacaagttct gcgggtgcat
     6541 gatttgtcac tattgcgttc gaaactcccc atcgttctat attttctgat aaaatcttcg
     6601 cacgtttcgg aaagatctca ttcgtcacta ataacccttt ccccttcatt tgagcagcta
     6661 attgggttga tttaccaccg ggagccgcac acaaatccaa aactttttca ccgggttttg
     6721 ctgcagcagc tgttccaacg atcattgcac ttggttcttg gctatattca tacccagctt
     6781 gatggaggaa agactttcca ttgacagtgc caagaaatcc ctcattgctg tagggagcgg
     6841 gttgtaattc ttcgctatgg taagtttgga ccatgtccaa tcctgccggt tttagtggat
     6901 tccaccgaaa tccttttttc acgcttcctt gttcaagcgc agaaaaaaaa tcggatgctt
     6961 cttcgcctaa aagaagacga tattttttga taaattgctg tggtaacgtt gtcgcttcct
     7021 ccttcattcc aatgtttcgt tagacatttt acaatctttt ttacgaaaaa taaaggtggc
     7081 tgatctactt tttcatgttg ctgcctaagg tgactgttcc tttaagatat tttccaagta
     7141 ttcatccgtc acctcgtttt tatcccaaac agcgttcatc atttcaagaa aatcttgaga
     7201 agaatcatct gagcgcaaac ttcccaatgc attaagccat accaattcaa gcgacttttc
     7261 ttctttgatc ttcgtgtgac ctttgacata tgagaaaaat ggccgcttaa atagcgaatc
     7321 catgtctaaa tcagattttg caatgatttc acgaatactt tcatggatag aaaaaaaatc
     7381 tttcaataag tagacaatgc ttaaaacatc atcggaactg cattcagcta agtagttttc
     7441 aaaataaaca gtgatttctt ctaatatctt ctcttttaac ccgctgattg atttgaaatg
     7501 tgtataaatc gggtatgtag aacaaccgca gaactctgct aactctcttg cagtaattga
     7561 cttcattcca tattcttcca cgtataccat acttttgaac agcaaatatt ctttactata
     7621 atttgttact ctccccatca ttcttacctc cgtctctttt catctaccca taaataaata
     7681 acataaataa ttctaaaaat attattgata attatcaaaa catatttagt tatatccatt
     7741 aaaaatcaat ttttccgcct taaaaacaag aatatcttga caaaataccc taggaaataa
     7801 acaatagaat aaacaaggta acaaaaaaat taaataacgt tatataaaaa agaaggcgac
     7861 actctgtgag aataacacag actgaaatga ctttccactc acagtttttg tctaactata
     7921 tacaaaaaca gaataaaaag gaggtattta tgctaattga agcaagaaaa aaagagttac
     7981 ttgttctaca aatggtcatt caaaaaaata attgttcttt acaagaatta tccaatgact
     8041 tacatattcc aaaacggaca atcaaagaac tgatccgaaa aataaatgta tcactcaagc
     8101 aatttttatt gattgatgaa tttatttatt ctaatcataa aggagagatc caaaccaaag
     8161 aaaccgatca aactaaaaag ttagctgttt tttctaagtt aaaattatgc tacctaaaag
     8221 aatccaatcg ttttaactat ttgatgttac taatcaatta tccacaaact gctgtaccaa
     8281 aaaaatattt acttgaacaa ctttatatat cgccctccta tctcgaaaaa ctgacaaaac
     8341 agctcaatca ttccttaaaa aaattccatt tacggatcct atctgtaaaa aattgctgta
     8401 ctcttgaagg aaatgagtta tctatccgtc tctatcttta cttttttctt tcagatacat
     8461 ttggaggtaa cgattggcca ttttcctcac ttgaattaaa tgcactaaaa atgaacagta
     8521 cagatgagca aatagaaaaa atttcaaaac aagaaaaaaa tatctacttg ctgttaactt
     8581 tattcatatt acgaaacaaa caacaggcat attttccaaa aacttcttct gaaatcactg
     8641 aattgatgga cttattgcag catacacatg attattcaga atactttact tctttttcag
     8701 tgagtcgccc ttgtgaagag acagaaacag agagagccta ctttaattat tttttctatt
     8761 gtttttttcc aaatcaaatc tcttttcgac aaaaacagga gattggtttt ttattttcca
     8821 caagcaaaaa ccttatttgt cgacaagtcg gtcaattgat gacttactta actcaacagt
     8881 ttcctctcaa ccatttagaa aataaaatac caatttattt ttattttctt gtgttggcag
     8941 ttgttttttt cgaactgttg ggtgaatcca gcagtagttt ttctacactt tgctttccag
     9001 aagccacgtc caatcattct agttctttta tacaggaaaa gaaattaaga gaaaaaatcg
     9061 atacaatttt ttcaaaaaat ggggaaagaa accaaatcag tcaatacctt agtcaattga
     9121 tccaacactt actacaaaca gaaacgaaag agcagttact catccatttg cagataacca
     9181 aacagtttac aggaaattat catcttcaaa gccatttgca gcagttattt cgcaaagatg
     9241 ctgttaaaat taccgcatat tcagaacatg ctgatttgat cattacagat cagcatgaga
     9301 aaatttcaga tgaaacggag actttctatc tggatacaac gcacaataca gtgttatttg
     9361 gcaagttaat aaaagcggtt catgaactgt atatgaaaaa aggttatgag aacaaaacaa
     9421 agaggatgtg acaaaattct tgtcacatcc tcttattcca aataaatggt attcaatcag
     9481 ctaactctcg gtattagctc agatcaaagc gctgatttca caacttcttt attttaatct
     9541 cttcggttgc cgccgaacaa taagatcaag cgcaacagct gcaggaatgt cgaaagcgct
     9601 gctgcaacat aagtcagtgc tgctgcaaat aatacgtgtc ttgccatcgg tacttcttct
     9661 tccgtcagta gtccgccttc actcaaaatt tggattgctc gccgagacgc gttaaattcg
     9721 actggtaatg tcaccaattg gaaaagtaat gctaaagaaa aagcgaaaat cccgatattg
     9781 attaacgtag agttccagct aagcaataca cctaccataa tcaaggggaa cgaaatcatc
     9841 gaaccaaagt tagctgctgg aacaagtgct gcacgaatct tcaatgggac ataacccgaa
     9901 gcatcttgta ccgcatgtcc gcattcatga gctgctacac ctatcgcagc aactgaagta
     9961 gactgtgcag ttgcttgaga caaactcaac atcttattac ctgaattgta gttatctgtg
    10021 agatctccgg caatttgttg aacaccgaca ttatttatct gttgactttg taatatatat
    10081 tgtgctgctt gtgtaccagt cacattgttt ttgcttctca cttgatcgta ttttcggaaa
    10141 gtactattga cgtacgctga cgcaattccg gaaataacta atccaagaat gaccaaaaga
    10201 aatgtcggat ctaaaaaacc atacattcca taaccataca ttttcgtttc actccttttc
    10261 gtttacttta ttttatcatt agtagtagga aaagaatgtg aaaagacctt gaatattctt
    10321 taattctttt tcacaaattc cgatttcagt ttcatcggtc caaatccttc taccttgcaa
    10381 tcgatattat gatcgccttc tactaaacgg atgttcttga cttttgttcc ttgtttaatg
    10441 gcacctgacg caccttttac tttcaagtct ttaatcactg tcacgctatc gccctctaac
    10501 agacggtttc catttgcatc taataccact aatccgtctt ctatgacagt ttcttgttct
    10561 tctttgttcc attcgttccc gcattctggg caaatcaaca agcctcgatc ttcatatgtg
    10621 tactctgagc cacattctgg gcaatttggt aatgtcatct tctttctcct ttaaaatctt
    10681 tagtgagcac tattgtaacg gaaaaagaag atcttgaaaa gatacatttg tgatttttac
    10741 tacaaaaggc acgttttcga acgaagtatc attctgtttt tctgctctta tacgattggc
    10801 atatatcttg gatctcttta tagatttcct ctacttctgc taaatctttt gcattcgcac
    10861 cacttgctaa tggatggcct cctccatgat ggcgtttagc caattcattg atgatcggcc
    10921 ccttagaacg taaacgtacg cggtaatacc ctgaaggctg ctgaacaaaa atcccccaag
    10981 ccagcacttc gtcaatcact ccaggaagtg aaacgatcga agctgtctct gaatcatcga
    11041 ttccatattt atcaagaatt tcttgcggaa ggattattct tcctgcacca ttttcatcca
    11101 cctggatatt ttgataaaga taaccggaaa gtttagcgac tttcatcggc atttgttcaa
    11161 tctctctgtt caaagcactt gcatcaaatg gataatttct caatatcgaa gcaatctcta
    11221 atgtacggga cgtcgtggag ggatacaaaa agcgccctgt atctccgacg attcctgcat
    11281 aaagtaaccg tgcagcctta acgtttatct ttaaagattc aggaaacatc aaagcaaatt
    11341 ctgcaatcat ctcactacag ctacttgctt ttgtatttac ccacacaaga tctccataag
    11401 ggtcatcatt gggatgatgg tcgattttga tcagtttttc tgccaactga tatctttgat
    11461 cactgattct gggtgaatta gctgtatcag tcacgatgac tagcgctcct tggtagaaga
    11521 catcttcaac ttcttgcatt tctgctaaaa agcgaagccc ttcaatcgtt tcacctactt
    11581 gacgtatttc tttttctggg aaactttccc gtaatagttc ggctaatcct acttgtgatc
    11641 ctaatgcatc aggatcaggg cgcaaatgcc tgtggataat gattttatcg tattttttta
    11701 ttgtatctac tatttcttgc tgtactgtca tttcactcct gctttctaag aacgttccat
    11761 tacttgacaa acaacgattg ctttggaaac gatggtgttt tcaataaaca cttcgatatc
    11821 cagtttagcg gaacgtctgc cgatttccaa tacacgtgga cgaatgtcta attcgctttc
    11881 caattggatc agccgcaaat aatgtaggtt cacttgttca atcaagatat ttcgtttttg
    11941 gttcatcacc attgtttttt gtgcgacatc agaaatgatt tcgctaagta cgccaaaaga
    12001 aatggttcca acgccattga ccatttgtgg tgctactacg aatttgaact tagggttttc
    12061 caaacgattt ccttcacggt cagtatcaat cgtatggata tttccagata tctgatccga
    12121 aatcgtatct gcaatctgcg gttgtcgctg gacaagctgc atcgctttca ttacatcttg
    12181 ccgggtaatc aagccttcca atgtcaagtc atcggaaacg accggcatga cttctagccc
    12241 atcccagatc atttgatggc taacagaggc aatactcatt gttttcttta cactgattgg
    12301 ttctttcgtc atcacccgat cgatgatctg gtttggcgat ttccctaaaa catcttttgc
    12361 cgtaacaatc cccatcaaac gatgatggcg gttgacgact ggaaaacgcg aatgctgcgt
    12421 ttcttctgac aaacgctgat aatcagaaat cgtatctgtc tgctgcaaat aatgagtctt
    12481 ttcagctggc atatagatat cactgacaag catgatatct tttttgatca attggtcgct
    12541 taacgctcgg ttgatcatgg ttgcgactgt aaatgtatca taagaggtgc gtaagatcgg
    12601 catttcaaga tcatcagcta gctttgcaat ctcagcagtc gtattgaatc ctcctgtgat
    12661 caatactgcg gcgccatctt ccaatgctaa tttttggact tccgcccggt tgccgacgat
    12721 cattagtgat cctggcgtaa tatagcgttc catggcatgt ttagtcatcg cgccgatgac
    12781 gaatttattc aagaccttgt ctaatcctgc cgccccgcct aaaacgtccc cttcaatgat
    12841 cctgacgacc tcgccaaatg tcaaacgttc aatatgtttt tttaatttgc gttcgatacg
    12901 gatggtccct actcgttgaa ttgttgaaac tagtccgaca ttttctgcat ctttgattgc
    12961 acggtacgct gttccttcac tgacattcaa ttcttttgcg atgcttctta cagaaattcg
    13021 attgccaaca ggtaaacttt caatatattc taaaatcaaa tcatgttttg tcgccatttt
    13081 ctgcctacac ttccagcgtt tccgagacgc tcattatttt tccttcacta tcttccagta
    13141 actctacaaa agattcggga tcttgttcaa tgacagggaa agtattgtaa tggattggaa
    13201 ctactttctt ggcacgaatt gtttgcgcag cctttgctgc atcttctggc cccatcgtat
    13261 agttatcgcc aatcggcaag aaagcgacat caatatcgaa ttcttctgca agcaatccta
    13321 gatcactgaa ataagcagta tcccctgcat gataaatcgt ttttccttct gcttgaataa
    13381 taattccgct aggctcgccc atatactgaa cgataccgtc tacttcatag cttgaactat
    13441 gctgtgcatg tacgaatttt accacgccga atggaaacgc atgttttcca ccgatattca
    13501 taccgaatga atctactcct ctgctgttcg cataatcagc aatctcaaca atactgataa
    13561 ttgtggcttg attttctttt gcaataggaa tcatatctcc tatgtggtca ctatgaccat
    13621 gagtaatcag caaccaatct gtctttactt cttctgcagt taagtctgtc aatggatttc
    13681 ctgtaataaa cgggtcaatc atcacgcgtt ggccattttc catttcaatt gttaaacagg
    13741 aatgtccatg atacgtaatt ttcatatttt acacctcgcg ttttctctgt atctttttta
    13801 ttaaaaacga tttcatcact tgcacatcaa tgaaaaaata tagctgctaa atatattttc
    13861 attggattga tagtacagta tgtacaaagc aattgtaaca gataatacag gatgcaccaa
    13921 gtaccaagca gatataatct caagtttgag gtctctgctc tgcttagctt ctcttctcgt
    13981 cccttaacta attaaatcag cgtaaatagg atggacgatc ttttctaaat cggctacttt
    14041 tatccgaagg cttctcccga tttcaccgct tgacacaatt acttcttctt tttcttttaa
    14101 agaactgtct gctaaaaaac aataatcagg atgtgcgagt tttattccaa taggggtgtt
    14161 tgctccgtgg ggatatcctg tatgcattaa tacaaaatcc attccaggaa aaccaacttt
    14221 acgatctttc gtcacttgtc tcgttttttt gtaatctaag tgatcgttca aaggaatcaa
    14281 tgcgatgatc accccagttt tgtttccttt cactacgaga gttttacata tcaaagctgg
    14341 atcaatccct cttttttgta gttcttctgt gaaagattct tctaccacat gactaaaatc
    14401 aagtggttga tagctgatct tttgttcttc taaataacgt tcgacttttg tttgactcat
    14461 cattgattca ctccctttat tctatcgttt attataaagc gagggatgct gtattcaaaa
    14521 attatttgtt tttcgcaaaa aaagagcaag acgagcactc tatagagagg ttcatcttac
    14581 tctttttgtt tattttttat ttcgacgttg agtagcttcc ataatgactg gcaagatcac
    14641 tgggcggcgt tttgtttgtt caaataagta acggcctaat tgatctcgga tgtcttgctt
    14701 taatttgctc cactcaaaat cattgctttc taaatgtttc tcaacgattg tttcaatcat
    14761 attgctgctt tctttcatca gatcacggct agcttttacg taaacgaatc cccgtgaagt
    14821 aatttgaggt tttgaaatga ttttcttttc tcgccgactg atagtgacaa ccgctacgaa
    14881 aatcccgtct tctgacaaga tttttcgatc acgtaaaaca atgtttccga tatcacctat
    14941 gcctaatcca tcaatcatta cattttctgc acttgtagtt cctgcaacac tcatacgctt
    15001 gttcttatat tccagcacgt ctccgcgtcc agtaatatag atatttttgt atggcatccc
    15061 tactgcatga gccaaatctg catgagcagc taattcacga tactctcctt gaactggcac
    15121 aaaatatgtt ggtttcatca aattgatcat taattgcaag tcattaggat tggcatggcc
    15181 agaaacgcgc atattctcag agatcaactt cactgttcca ccagctcgat aaatgatatc
    15241 ttccgttttc gccacgatgg tttccatcgc gatgcttggc gtagtagtga tataaaccaa
    15301 atctccttct tcaatcttga cattacggtg tgtaccgttt gccatttttt gcagagactt
    15361 gatgggttca cccattcggc cagtttctaa aatgatcagt tcttctggat catagttttt
    15421 catgtctttc aacgtaacaa gcagatcttc acttggtaat tgaagttttt ctaaacgcat
    15481 cgctgtgcga ataattcgtt cgaaatcttg accagtcaag acaacttttc gttgtgcttt
    15541 ttctgctgca tccaatactt gttgcactcg ttgcaaatta cttgctacac aagcgacgat
    15601 gatacgccct tcccaatatt tgatcgtatc aaatacttca tctgctattt gggcttcaga
    15661 agctacaggc tgaggatttt ctgcatttgc cgattcactt agtaaggcta agactccttc
    15721 tttgccgatt tccgccaatc gtgcataatc tgtttgatac attgggatag ccgtttggtc
    15781 aaatttaaaa tctcccgtat aaacgatact accttctttt gttttcagat tgatccccac
    15841 tgaatctggt atcgtatgag tggtacggaa aaagctcact actgtttcac caaagtctat
    15901 ttctgtatgc tcatctacca catggaaatc cttaaatcct ttggctgctt cattacgact
    15961 gacattcaat tttgctaact cgatcgtcaa ctctgtcccg aatactggta cagaaatttt
    16021 tgacaacaag taaggaagtg ccccgatcgc atctgcatgt ccatgtgtta aaaagacacc
    16081 agctacacga tcaatgtttt cttctaaata cgtaaaatca gggattacga cgtcgatccc
    16141 caacaactca ttttcaggat attttagccc acaatctaaa ataaaaatat cctcgcccac
    16201 ttctgcgaca tacatgtttt ttccattttc acgaacgccg cctaatggga taattttaat
    16261 ggtactcaca aacttcacct cttcttatga catccaagtt taaagatgtc gattttcttc
    16321 tttatctaaa tatatgagcc attccaatga agcatatgca aaatcactat ttctcaactt
    16381 atggagaatc agcaggaaaa ttaccagcac atccgcgttc tgacagttgg atgggcattt
    16441 tattttggat atacttcatt aacaaaatgg atcttttgcg aaacgctata gccagaatac
    16501 ttatataagt attcagctgt tccccattat tatacaacaa ataaactaaa tcgctagtat
    16561 cagcaattgt tagaacaact atgcacgtaa aaatccctct gtagcatcta ggatttcttt
    16621 tgctattcct ctttcatttc ttcttcgtcg gtttgaaaca tacttttttc attttaccac
    16681 attttttgca ataactatag tgacttttta tatatacaga acctcatgtt gatggtgtgc
    16741 aaacagcata agatttaagc tagctttaag ataggttgtc tattatcaaa tgcatctact
    16801 aggagggatg caaaatatga attttatgaa acgtgcatgg aaaagtacaa aagtaaaatg
    16861 gggacgttca ttgttattgt ttgccgtgtt cacagccatt cttatttttg tgctagctgg
    16921 cctcacgatt cgaagcgctg cagaagaagc agcgaatcaa gcacaaaaag aagttggagc
    16981 aacagtgact ttaagtgcca atcgagaagc ttcatttaaa aaacaggaac aaacttcttc
    17041 aagcggttct accactgaag aacgtccaga tccaggcagt ttttctctta caccagtttc
    17101 cttaacggac gcggaaaaaa tagctgaatt agataatgta aagagttatt cctttgaaag
    17161 ttccgcctca gctatggcaa aagatggaat aactgccatc actagttctg attcaagtga
    17221 agacagttca gaaactactg atgcaggcgg tgaacctgct ggaggaatgg gcgggaatcc
    17281 gcaaatgact caagcagact ttcaaatcag tggtgtgtca gcaactgcac aaaatagtaa
    17341 tttttctgat ggaacagcaa aaatcacgga tggtgaagga atagatgaca gcgacaaagg
    17401 cacaaacaat gtagtcattg attctactct agcagaaaca aatgacctgg cagtcggaga
    17461 tactttcaca atcacgagta ctgaagatga agataccact tatgaaatga cgatcaaagg
    17521 aatttatgaa tccagcgaaa caagcggcag tatgggtatg aaattcaact tcatgaatcc
    17581 gtcgaataca ctttacactt cttacacttt tgcaaatgaa ctaaatggga catctgacga
    17641 taacacgata gattctgcta tttacactct atctgatcca gataaaatgg atgagtttct
    17701 caaagaagct gagaagctga tcgacacaga tacatttagc ttacaatcaa atgattccat
    17761 gtatcagtca atgttggaac ctttaaacaa cgtggcaagt ttttctaaaa atgttgtttt
    17821 actagtggct gtagccggta ttatcatact tactctgatc attatgatta ccattcggga
    17881 gcgtcggcat gagttaggcg tcttgctatc tttaggagaa tccagaagta aaatcattct
    17941 ccaattgttt accgaagtgg ctatttgtat gattcttgca ttaggagttg cttcgcttag
    18001 cggaaacgtc gtcgcgaatg ccgtgggaca gcagctactt gaccaacaga cagaaaccac
    18061 gacacaaaac cagcaagctc ctggcggtgg acaaatgcca ggtaacagac aagaacaagg
    18121 cggtcaacgc gatggtcaac aaggaaccac gaataatcca tttgctgttt ctgatcaagt
    18181 cagcgaattg gaaatcaatg tcaaacctgc acaattggga ctattagccg gagtagcatt
    18241 tggaatcagt ctgttttctg tctttttagc ttctataggg atattaagat taaacccaag
    18301 aaaaatccta ttaaactaaa ggaggaattt gatgttacgg acagaacaat tgggattttg
    18361 gtatcaagat ccgcaagatg cgctttataa agatgtagaa ctgaatttcg aagctggaaa
    18421 aatgtacgct attttaggag caagtggttc tggaaaaacg acttttcttt cgcttatttc
    18481 tggactagat gcaccaaaag aaggaaaggt atactatcaa gatcgttcac tgaacaaaat
    18541 cgggttaaga agttatcgta aaaatgatgt ctcgattatt ttccaagctt acaacttgct
    18601 tccttattta tcggctctag acaacgtcat agcagcaatg gaaatcacta agaccaagca
    18661 agagaattat cgacaagttg ctttagatcg actggctcgt gtaggaattg atgaaatatt
    18721 agcaaaaaaa caggtgacca aactttcggg aggtcagcag cagcgagtcg ctatcgttcg
    18781 tgctatctgc tgtgaacatc aactaatcgt agcggatgag cctactggaa atctagatga
    18841 aacaacttca caagatatcg tcaaactttt ccaagaaatc gcccatgaac aaaatcgctg
    18901 tattatcatc gtgactcatg agattgaagt agcaaaaagc tgtgatgaag tctttgaact
    18961 aaaaaataaa aaatttcaaa aaatcgaagt ttaaaaaaca ggataatgat caaataaaaa
    19021 atccgaacca tatctgtctc gcagatatgg ttcggatttt ttatttgctt gattcaatta
    19081 gtaataagtg gtttttattt tttttcgtct tttcgagaaa acttgtcttt gacttcgtcg
    19141 cctaaatttc gagctttttc tttgatgtca gcacctagtg attgtgcttt cccttctgtt
    19201 tctttgctct tgtcgtctgt tgctttgccg tatgcttctt ttccttcacc gactacttta
    19261 tctttcatat ctttagaacg tccttttaaa tctgccattg tgcttcctcc tcttagtttg
    19321 tttattgatc taccttcagg gtaacatcaa caacagatac agacaaacag aacgctcgtt
    19381 ttctaaaaaa gatagttaga gctgttgatt aaaaactttt ttcgaaagtc ccccatactt
    19441 tgacttcttt ttcttggacc attatttctc ctttagcgat aactgtatca atatcaagcg
    19501 tttctttatc caagatacac agatctgcat cagcaccaat ttcgattttt ccttttttat
    19561 ccaatttcaa tatacgtgct ggattactgg ttatagctcg taaggcgatt tccaaaggga
    19621 tactttcttt ttgcacagct tctttgatcc ctactagcaa tgccttggca cttcctactc
    19681 ctaaccctag gaaatgattg ttttcatcaa aataaggcaa gcttccttgt ccatctgagg
    19741 tcatcgtgaa attatctaaa gaaacatctt cctcgatcaa tcgtttcagt gctttgctga
    19801 agcgaacttc accatctgtc ttctcccaaa aatcaggatc ttcgctagca gtgaagtcaa
    19861 tcgtgccacc acgtttggca aatgccacgc aagcttcaaa taattctggt gtgcgatttg
    19921 catgagtagg caaaaattgt gtgatcggaa tttctgtttc ttctacgatt cgtgtcaata
    19981 gctctagctt tctttttcct ccgcctaagt ggacattgat gatcccagct tttccggata
    20041 acatgcctcc tacacgagca tctgctactg cacgagcgaa ctcttcaaaa cttggctgag
    20101 aagaacggtg atcggatact gcgatttctc cgattccgat aattttatca attgtcaaaa
    20161 agtctttgat gatagaatct gttactgttt ttaccggcaa tcggtacgaa ccttcgtata
    20221 cataagtgga gattccttct gcttccagac ctttcgcttt gctgatcaac gcagtcatat
    20281 ctctaccttc tccgtctgtt cccaaacaac cgacaactgt cgttacacca gctgtagtca
    20341 attggctcaa tgtgacttct ggcgttcgat tttgataacc gccttctcct cctccaccta
    20401 aaatatggaa atgacagtca atgaaacccg gggttagtac ttttccctca cctgaaagtt
    20461 cttctacttc cactccttcg tagccgcctt ctagctgttc ttctacagcc aaaatcttcc
    20521 caccggcaat cagtacatcc atttttccta agtaatctgg tgcaaacact tcaatttgtc
    20581 gaatgatttt catacatttt tcctctttct ttaagtataa ctgatgatag gatcttaaaa
    20641 aataatccaa acgataggat ctttactcct ttgattttac cgtaaaatga cggttcttgg
    20701 agtccttatc tactgtttgg attacttttt tatttacagg tctccagtac tactgcagac
    20761 ctattgcaat ggcaatcatg atgaaaatag ttcctaaaac aaacaggaat ccttgcatct
    20821 tgatttggaa tcttgcccat tttgcccatt cgatccgtgc aacacctagc acaccaatca
    20881 agctggctga tacgggtgta aaagcgtcca taaaacctga accaagctga taagcaagaa
    20941 ctgctacttg tctggataca cctactaaat ctgccagtgg agccatgatt ggcatagtca
    21001 aagctgcttg tcctgaattt gatgtaacaa ccaagttgaa caaactttgg aagatgtaca
    21061 tcgcccaagc accaatgaca gctggaacac cggtcaacgc cgtcccgatc ccatgcaaaa
    21121 tcgtattcaa agctgaagga acagatgcat cagatcctcc caagacaaga agaatccctt
    21181 tggccatacc tactacgatt gctgtaccag ctaaatcagc tgcaccagat tggaaagaag
    21241 aagcgatgtc attgactttc attccatcta atttgaaaag aacagcaatg attccagcaa
    21301 ctaatcccat cacaaagaat tgagaagcga tttctggaat gtaatagcct ttttgagtca
    21361 cgccccaaac gatccagaca aggacaacta acatctctaa taagatcaat ttatgcccaa
    21421 gcatgaattt tttattttca tcagatgtct ttttgatatg agaacggaaa taatcatctg
    21481 atttgtaagt caacgaactt tctggttttt tacggatttt ttctgcatat atcatcatat
    21541 aaccagcggc taatgcagta acaactaccc acataatcaa tcggaatgtc gcaccagaca
    21601 acacggggat tccagcaatc ccttgagcca ccgctacgct aaacgggctc atccaagagg
    21661 tcgcatttcc gacttgagat gcgacataag tcacggttac tgctacgatc gagtcatatc
    21721 ctaacgcaat gacaaatgga accatcacca ttgagaatgg aattacctct tctgccatcc
    21781 cgaatgtagc gccaccgaat gaaaaagcaa agaataatag cggtaaagct aaacgctcca
    21841 gtcccttagt tttactgata aacgcataga tacctgcgtc gatcgctccg gtacgcataa
    21901 taataccaaa agcacctcca acaacaagga tcaatgcagc gatccctaca gcagatccat
    21961 acttatctcc agatactagt ccttcaaaaa caaaatttaa gaaaccaaag ccgccaaaat
    22021 catctgttcc ccatattttg gctgttttat gcaatttttt agaagtatca tagatatttt
    22081 cgccgtactg atcgtaaagc acatcatctg tcaaggagat ttcatctagt ttttcctgcg
    22141 taagattttt ttctccgtca gcaatgactt tttccaatcc tttttccgga acatccagtt
    22201 tttcacgttc tgctggatga tcttgcagtt cttctaattg atcaaacaca tacgacttat
    22261 ccagctcgta agcataacgg aaggaatctt gacgtaaaac agtacgagta cttgtttcgc
    22321 catttgcatc tttgtattca atatcttgcg tgctgaactt tcctgctgga acgacaaaag
    22381 tcagtatcca tgcaaagatg actacaccaa aaataatgac atacgtatgg ggtgtcgata
    22441 atttagtgaa gtcgcgtttc ggttttcctg aagaatttgt tttcttcaaa tttatttctt
    22501 cctttctttt ttcagtaatt ttgatgaata aaaaatggat aatcaaatga attatacagt
    22561 aaaaatgaca tttccacatg aataatttat tagaaaatca cttttttcta ttttgttttt
    22621 ttctcctatg tatgattatt
//
LOCUS       DADQCX010000042        22279 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.042, whole genome shotgun sequence.
ACCESSION   DADQCX010000042 DADQCX010000000
VERSION     DADQCX010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.042"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            349..2184
                     /gene="tdc"
                     /locus_tag="J8R83_001504"
     CDS             349..2184
                     /gene="tdc"
                     /locus_tag="J8R83_001504"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAZ9574635.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2489..3967
                     /locus_tag="J8R83_001505"
     CDS             2489..3967
                     /locus_tag="J8R83_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9574636.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3933..5264
                     /locus_tag="J8R83_001506"
     CDS             3933..5264
                     /locus_tag="J8R83_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9574637.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5378..7930
                     /locus_tag="J8R83_001507"
     CDS             5378..7930
                     /locus_tag="J8R83_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAZ9574638.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7937..9376)
                     /locus_tag="J8R83_001508"
     CDS             complement(7937..9376)
                     /locus_tag="J8R83_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9574639.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9722..10084
                     /locus_tag="J8R83_001509"
     CDS             9722..10084
                     /locus_tag="J8R83_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574640.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10271..11128)
                     /locus_tag="J8R83_001510"
     CDS             complement(10271..11128)
                     /locus_tag="J8R83_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9574641.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11248..12159
                     /locus_tag="J8R83_001511"
     CDS             11248..12159
                     /locus_tag="J8R83_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAZ9574642.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12166..13812
                     /gene="mdcA"
                     /locus_tag="J8R83_001512"
     CDS             12166..13812
                     /gene="mdcA"
                     /locus_tag="J8R83_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAZ9574643.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            13914..14213
                     /locus_tag="J8R83_001513"
     CDS             13914..14213
                     /locus_tag="J8R83_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAZ9574644.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14203..15879
                     /gene="mdcD"
                     /locus_tag="J8R83_001514"
     CDS             14203..15879
                     /gene="mdcD"
                     /locus_tag="J8R83_001514"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAZ9574645.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15883..16476
                     /locus_tag="J8R83_001515"
     CDS             15883..16476
                     /locus_tag="J8R83_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAZ9574646.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16500..17576
                     /locus_tag="J8R83_001516"
     CDS             16500..17576
                     /locus_tag="J8R83_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAZ9574647.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17601..18470
                     /gene="mdcB"
                     /locus_tag="J8R83_001517"
     CDS             17601..18470
                     /gene="mdcB"
                     /locus_tag="J8R83_001517"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAZ9574648.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18581..19345
                     /locus_tag="J8R83_001518"
     CDS             18581..19345
                     /locus_tag="J8R83_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAZ9574649.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19834..21927
                     /locus_tag="J8R83_001519"
     CDS             19834..21927
                     /locus_tag="J8R83_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9574650.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21952..22254
                     /locus_tag="J8R83_001520"
     CDS             21952..22254
                     /locus_tag="J8R83_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9574651.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7229 a         3793 c         4737 g         6520 t
ORIGIN      
        1 tgttataaaa tttggaaaac agataattct attaaaaaat aaattgcgaa tttttaacaa
       61 tataaaaaaa taaaaatatg tttagtgaat gaaggacagt cattttattt gtttgttcgc
      121 tttttttagg ttatctattt tagaagactg atttattgaa aaattgttcg cttttttgcg
      181 ttgaattatc agaaaaatcc gactttattt atttttgttt gtaaaaatct acgtggattt
      241 gatgttataa aaaaaaaatt ctcatttttg gcgctatagt gaagaggtgt tacagataaa
      301 cacatgtatc tgcaagacat tgaccaacaa aatatggagg gaagaaaaat gaaagatatg
      361 gatatcaagg ccgtctttat aggcgacaaa gctgaaaatg gaccagttta taaaatgttg
      421 ttgaacaaga tggtagatga acatcttgga tggagagaaa attatattcc ttcagatatg
      481 cctgcaatta gcgaaggaga taagctcact ccagattatc tagccacccg cgaccatatg
      541 atagaggtct tggatgaagt cagtcagcga ttacgcgcag gatcgatccc atggcattca
      601 gcaggccgtt actggggaca aatgaatgct gaaacattga tgcctgcttt attagcttac
      661 aactatgcga tgctgtggaa cccaaataat gttgcattgg aatcttctat ggcaacttcg
      721 caaatggaag cagaagtagg acaggatttt gcttcattat tcaatatgac agacggatgg
      781 ggacacattg cagcagatgg ttctattgct aatcttgaag gattatggta cgcccgttgc
      841 atcaaatcga ttcctttagc tgtcaaggaa gtgctgcctg aaaaagtgaa aaaaatgtct
      901 gagtgggaac ttttgaattt atctgttgaa gaaattttgg aaatgaccga aagctttacg
      961 gacgaagaaa tggatgaggt caaagcagct tcttcccgta gcggaaaaaa tatccaaaga
     1021 ttagggaaat ggctggtccc tcaaacaaaa cactattctt ggatgaaggc gttagatatt
     1081 tgcggagtcg gcttagatca gatggttgct atcccagttc aagaggatta tcgaatggat
     1141 attaatgctt tggaaaaaac aattcgtgaa ttagctggac aaaaaatccc aattctaggt
     1201 gtggttgctg tcgtaggaac gacagaagaa ggtcaagtag acagtgtaga taaaatcgtc
     1261 caattaagag aaaggttaaa agatgaaggg atctatttct atttacatgt tgatgccgca
     1321 tatggcggct atgcgcgttc actgtttcta aacgaagcag gagaatttgt gccgtatgct
     1381 tccttagctg aattctttga agaacatcat gttttccacc actgcgtaac gattgacaaa
     1441 gaggtatatg aagggttcag agctatttca gaagcggatt ctgtcacgat agatcctcat
     1501 aagatgggct atgtccctta tgctgctgga ggaatcgtaa tcaaacataa aaatatgaga
     1561 aatatcattt cttatttcgc gccatatgtg tttgaaaaat cagtaaaggc tccagatatg
     1621 ttaggagctt atattttgga aggatcaaaa gctggagcaa ccgccgccgc agtctggaca
     1681 gcacatcgtg tattgccatt gaatgtgacc ggatatggtc aattgattgg ggcttcaatc
     1741 gaggcagctc aaagattcag agaatttctc gatcatctga cttttactgt taaaggaaaa
     1801 acaatcgaag tctatccatt gaatcatcct gattttaata tggtcaattg ggtattcaaa
     1861 gaacaaggct gtacagattt gaacgctatc aatgaattaa atgaaaaaat gttcgatcgg
     1921 tcttcttata tggatggcga tgtttatggt gaacggttta ttacttctca tactacattt
     1981 acacaagaag attacggtga ttctccgatt cgttttgttg aaagaatggg tctaacgaaa
     2041 gaagaatgga aaaaagaaca gaaaatcact ctgctacgtg cggctatcat gactccttat
     2101 ttgaatgatg atcgaatttt caatttttat acaaaaaaaa tcgccaaagc aatggaaaag
     2161 aaactaaacg aaatcatcca atagaactga tttttgtgtg aaagaataac aagagacata
     2221 tggagaacag acaattattt gcttcatcaa aacaattgta tttccccctg tttttcatat
     2281 attcctcgcc aagatattct tttttataaa acgttctata agttggatcg ttcgtttcat
     2341 gtatcaaacc cagttcacta agatcgttca atggatgttt cggtgatact gggttttgta
     2401 ctgaatcgat gaaaccttgt catttctgtt cttgaacaaa aataaaagaa aacaaaaaca
     2461 tatgtcgcta ttgaaagaag gaataaagat gaaagatact ggttcatcaa agcaaatcac
     2521 gaccatgacc tttatcggaa tgacctgcgc ccttgtagca agtgtacgaa atattccaga
     2581 tgtagcagca acgagctgga cgatgatttt ttacatgctg gttgcagtat tattgtacgc
     2641 ttttccaatc tcattgatct ctggtgaatt tgctggaatg tttccccaaa aaggtggtcc
     2701 agaactttgg gtatcgaatg ctctaggaaa aaaatggggg ttcgttgtct catggctgtt
     2761 atgggtccaa atgtttcctg ggatggtgat ggtcgcttca gcactcgctc cgttgtttgg
     2821 taatattatc gataatgtgc cgcttggttt gaacagcaaa tttacattag ttgtcatttt
     2881 agtcgtttat tggatcatca cttttttgaa tttgaaattt gatatggcaa aaatcggcgg
     2941 aaaagtcggt gtttggttag gattgtacgt gcctttgacg atgatgctct tattagggtt
     3001 tgctgcgtgg atcaaagttg ggatcgtacc aaccggaaca ttaggcagtt tttcatggga
     3061 caaattaata ccagatacta cgactgcatc ctcatttgtt tattttgcgc cgatcatgtt
     3121 tatttttact ggtatcgaaa tgtcctctgt gtatatcact cgattggaaa atccagttaa
     3181 aacgtatatt cgcggagtat ttgccgcgtt aatttttata tttttcgtca atattttgaa
     3241 tgctttagtt gtagcaaatg tcgtaccaaa aggacaaatg gaattgaata atatcgcgca
     3301 atctatttcg atttattgcc aaattcttgg tttgccacat cttattgtga atctgtttag
     3361 tttacttgtc ttcattggtg tagcagtcca attatctgct tgggcctcag gaccagcaaa
     3421 gacagtgaca gaaagtgcta gaaaaggtgc gtatccacca aaattcaatt tttggaagac
     3481 gaatcaattt gacgtatcca aatccgttat tttgactcag tctgtcatta tctcaatctt
     3541 tgcacttttt tatttgctga ttcctggcgt caatcaagca tttttgatgc tcgtaaattc
     3601 aactactgtt atctactgta tcgtctatgt catcatgggg atcgcagttt tgagattgcg
     3661 ttatacacat gcaaagttga atcgaccatt tagaattgga aaaaaagaga aaaagagcaa
     3721 tcttggagtt tggactgtcg ttattgtttt atttgcggca atcggatttt ctgtcggact
     3781 gacgatgaaa gctggaacat ggatcaatct aattgcagtc acagccatca gtgtcatttt
     3841 gtttgtagta ccactctgta ttgaaaaaat aaagaaacct tcttgggaac aggaagtcgc
     3901 catgctgctt gaaaaagaaa aaggtgaact tgatggaaaa accggcaatg aaacggactc
     3961 taactaatcg aaatatccag ttaatcgcat taggtggcgc aattggaaca ggattatttt
     4021 taggttcagc aaaggcaatt gcatcagcag ggccagctgt tattctcgtt tatttgatat
     4081 gcggtttggc tatttatggt ttgatgcggg ccatgggtga tttattttta gcaaatagta
     4141 catttaactc tatcagtgat ttcgttgact attatttagg caaaaagtgg gcattttttg
     4201 tcaattggac ttattggctt tgctggcttg gagctggact tgcggaatta acagcaatag
     4261 gattgtatat ccatttctgg tttgtacatg taccagcttt gataagcgga ggtagcgcac
     4321 taatgatctt aatggcagtc aaccttgttg cagtcaagtg gtttggtgaa ttggaatctt
     4381 ttttctcaat catcaagatc ttggggattt tcctttttat cttattgggt ataggattga
     4441 gtgtctcaga ttttcatacc cagtctatcg gaatcaaaga aaattttgga cagatcgatg
     4501 aattactacc gtttggcttt gctggaatgg tagtctcatt tcctatggtt ttattcagtt
     4561 ttgctggaat tgaaatgatc ggcttaaccg ttggcgagac aagtgatccg caaaagaatt
     4621 tgaaaaaagc aatcaactgt ctgccttggc gtattctctt tttctatata ggaacgattt
     4681 tgtcgatttt atttgttgtt ccatggcatt gtttagattt aaaagaaagt cctttagtga
     4741 ctatgctgca agtgatccat tgccaaggcg gagcagcaat tgtcaatcta atgattttgg
     4801 ttgcttcttt gtcctcagca aatagtgcag tctacagtac tagcaggatt ttatatcaaa
     4861 cagcaaaaga aaaaagtttg ccccattggt tttgtgcgct ttctaagaaa ggcgtacctt
     4921 tacacggtat tttaattaca ggaatgttat tttttgccgg tctttgtcta catttttttg
     4981 tagctgatag tcgattgttt tttcagcttt tggcaggcat gacaacgagt tgttttctat
     5041 ttgtgtggtc ttcgatcttg tgtgcacatg ttcaatttat taaagaaaag aaacggaaca
     5101 ctacacaaag atataaagat cttgctttgt tggtgttttt tacttcaatt gctttcagct
     5161 tgttattcga aagcacgaca cgctttattc cttttttatt ggttatctgg tttgtattct
     5221 taaattttgt atataaaaga ataagcaata gaaatatcag ttaggcccag atacattttg
     5281 caaaacgaat tatttcagac ccccctgaaa taatcgatac gcctgaaaaa acttccctgc
     5341 gtataataac agtatcaatt aaacaggagg ggataggatg aactggtaca gattgacggt
     5401 agaagatgta ttgaaaaact atcaaacatc aacagaaggc ttgtcgcaag aagaacgaca
     5461 gaaacgcctg actgatcaag gatataatga aataaaagca aggcagcaga caaaacgatg
     5521 gaaaaaaata gcaaagcatt ttactgatct gctgatgatc gtgttgatca ttgcctcttt
     5581 tttgaaattt gcttctagtg aatatattga aggaagtatt attttattcg tagtgatcgt
     5641 caatggactc gttagttact ggcaagaaag aaaagcggaa gaatcattga atggtttgaa
     5701 gcagctgatg ggacaagaag cgatagtact atcaaacggg atgcaagaaa aaatccctgc
     5761 gaaagaactg gtaaaaggag atgtcattgt cttacgtgcc ggagatgtcg ttccagcaga
     5821 tatccgatta atcgaagcac atgatttatt agtggaagaa tcgattttga cgggagaatc
     5881 agaagcatct gaaaaaagtc atgccgtttt gacagaagaa gaatcgatcg gcgaccagaa
     5941 aaatatgggt ttttcaggaa cgcttgtaca atctggttct gcagtcggtg tcgttgtaga
     6001 aacaggaaac acgacagaaa tcggtaaaat caatcaagca ttgcaatcgg tcgaacaaca
     6061 aacgacgcct ctgattaaaa aaatcaaccg attaaacaaa caaatttttc aaggcattct
     6121 ttgtttgagc ctattcttag ttatttttac gacatttcga tatggtatgg attggcatat
     6181 ccttctttcg gctacgattg ctttggtggt gtcaatggta cccgaaggat tgccagctgt
     6241 tttgaccatg attctatccg ttggagtaca tgaaatggca aaagaaaagg cgatcatcaa
     6301 aggacttcct tcggtagaaa cattaggttc tatgacagtg atctgttcag ataagacagg
     6361 aacattgaca aaaaatgaaa tgacagttgt ggatgtagct gcaaaagaag aagcctgcgt
     6421 gttgtccatt atgaaaaact gtcaggaatt aaaaacaaaa gaagaacaga aaacagaaaa
     6481 tttaagtggc aatccgacag aagttgcgct gattcgacac acagaaacag ccaatctacc
     6541 tttgaaaaaa atagaagcaa agattccgtt cagttctgaa tacaaatata tggcaacgat
     6601 gcatgcggag gaaaaaggag cggtgattta cgtcaaaggt gcaccagaag tattatttgc
     6661 taaatcaact ctttcttctg cagaacaaga agcatggagt cagacagctg cagaatttgc
     6721 gagaaaaggt cagcgtgttt taggatttgc ttataaaaaa gtagattcga aacaggaact
     6781 cacgcatgag actttaaccc aattaacttt tgcagggatc gccggattga tcgatccgcc
     6841 aaaagaaagt gcagtcaaag ctgtaaagga atgccaacaa gcagggatct cagtgaaaat
     6901 gattacaggg gatcacaaag acacagcaaa agcgattgcg gaacaaattg gcttaaaaca
     6961 tactgccaaa gttttagaag ggatcgattt ggatcttatg tctgatgaag agttgattca
     7021 gcaagtgcca atagtcgatg tctttgctcg aacgacacca gaacataaac tgcgaattgt
     7081 taaagctttg cagaaaaatg gagaaatcgt cggaatgacc ggagacggcg taaatgatgc
     7141 acctgctttg aaaagatccg atgtaggaat tgctatggga atcaaaggta gtgaagtaag
     7201 caaacaggca gctgatatgg ttttaggaga tgataatttc catacgattg caaaagccgt
     7261 aaaagagggc cggcggattt tggataattt gcaaaaaacc atcaatttct tcttgccaac
     7321 tgcattagct caaggattga tcttgatttg ggcacttatg ctgaatcgcc cgctaccttt
     7381 gtccccagta cagattttat gggtcaatat ggtaacgaca atcactttat cttatgcact
     7441 agggttcgag tcgccagatc cagaaatcat gaagcgccca ccaagagatc caaagcaagg
     7501 aatcctatct ggttatcatt tgtttcggat catctatgtc tccctactga tcatggttcc
     7561 tgcctattta ttggctatgc agtttgaagg gcaaagctta cagcaaacca ttcttctgca
     7621 aaatatcgtc ttagctcaag ctgtttacat gatcaattgc agagagttgt ccaagccgtc
     7681 attgaaccaa ggtcttttgc aaaacaaagc gctttttctt tcattaggta tccttgcttt
     7741 attgcaaggg atggttattt ttctaccagt cggccagcag ctgatcggta cagtaagttt
     7801 aacgatgaca caacagttat tgattggagc aaatgtgatt cttctattct tagttgtaga
     7861 aatagaaaaa gggatcatga acaaactgtt tcgcaaaaaa gaaaaaacag ctagagaata
     7921 cagtcgctag ccgttactat aaaaaagttt tgaaagtgag ttcagtcaaa cgattgagct
     7981 catttttcgt tggaatagaa gaaatgtata caatagggat atctagagaa tctagaggga
     8041 aattggaaat caagatatct gttttttcaa aagaaatagt ggaaagatcg gttagttcga
     8101 taggtaagaa gcagacacgt tttcctaagt aatcttttaa ttcctgctgc aagaacgcct
     8161 tccatgaagg ttctccttgg aaaataaaat agacattgaa caaattcggt ttgatagaaa
     8221 aaatcgtttg ttggatcagt agagacaaga gttggagaaa gtaatttggt tcattgattt
     8281 ctatttcttt ttttagatcg ttcagtaaat tctctttctg ttgatacaag tgtgcatatt
     8341 gctgatcata tgtttctaaa aaacgatggt attgacggtc caatgcttca atcaatatcg
     8401 gcgattcatg atattttaat atgaggagag ccaagttatc agtcagagat gtttttttta
     8461 gttgatcaag agacagctct gaagctagtt cctctacaaa cgtttcgagg acctctaaaa
     8521 atggagaatg atgcaggcag cgagcggttt cttgtccata gttattgttg taattccaac
     8581 tttccagaaa gcagaaagaa gcaaaagaaa gctcagtgtc tttaagataa ataccttccg
     8641 ttaaatacaa ttttttcaat gcagagtcat acagggagga gagtgtgctg ttggtatgga
     8701 tagaagaatc taatcggcaa ttcgctttta tacggatcgt attgataaag aaccaacatg
     8761 ttccgaaaat ctcttctgtt tcaaccgcta gttcagtttg actgaggttt cttaaaaatt
     8821 gaaaataatg ggattcatgg atcgaataat cctcgaaaaa atagttgtta tgagtgaaag
     8881 gaatcagcaa tcgatgataa aaagtacgaa tcgcacgctc ttttccaaga atacaagctg
     8941 tatatttcgt caaatcgatc tgcaagtcgt aacttgctaa acgctgattg attttagtca
     9001 catgtctttt caatgtccca taagaaagcc catggtcggc tagaaaatca gggacagcaa
     9061 ctttttttgt aaaaagcaga tttttcagca gttcgacact gactgattgt ttgaaaaaaa
     9121 tctcccaaag gtcatttgtt aataaatttt gctggttttg caaactgatt cctgcttgat
     9181 cgctgatgat gtcccagcct tcgggcagct gagagcgaat agattgaagg tcagaaaaaa
     9241 tcgttcgttc ggttgtccct atgatttcag ctaattcatt tacggttatc tttgtatgat
     9301 tcagcaattg ttctactaaa gaaacatgac gtcgaatatc tttttcggta atgatttttt
     9361 tcattagtga atacatcaat cagactccct tctattctaa gaatacggag aaaataaacg
     9421 gtggtcaagt ttcaactgat ttttcaatca ttgtttattt ttctggagca tttactgatg
     9481 ataagaattt catcatgaac ttgaaaaatg ataccactaa aatcaaaaaa taggtgggca
     9541 aacaataata aacattttaa tagtagatgg tagcaagacc aacacaggcg gattgaacat
     9601 ttaagagttg ataaaaaaga aaaatatcga agtatttgat tagcaactac ttgtattcat
     9661 ttttctattc ttacgtggta tctttgaata aagcgaatca ataagaaaga gatggaagca
     9721 gatgctaacg aaaaaagaac taatcgatca catcaatgaa acatacaatt tgtctccaga
     9781 atatattttt aaaaaatttc ctgattattg cgtattcaga catcaaaaaa gcaaaaaatg
     9841 gtttggggtc ctgatgtctg ttccagaaga aaaaatctat gatgatgcaa gtgaccatag
     9901 gatcatcaat attcttgatt tgaaggtcga tcctgaactt ggcggaattt tgcgaggaaa
     9961 agaggggtat tttccagcct atcacatgaa taaagaacat tggatctcta ttgatctacg
    10021 taaaatagaa aagctagatg aactagcaga tttgattgat ggaagtttta aatcaacgca
    10081 atgaatgtct aggacaatag agaagaggtt gtgacagaaa tgtttagctt caagaaataa
    10141 gaaggaattt acgaaaattg cttctcaaat ttttgggaaa tttcggctta ttttctaaga
    10201 aattacttct ggaacaccgt ttgttcgaaa aaagagctgc gacaagaatt ttgtcccagc
    10261 tctttttttt ttattttcct aaataaaatt cccgcatcgt ttttgcaatc attttgatca
    10321 aaggatgatc ttctgtgaag ctagaagata aataaattgt tcgtgtcaag ggcaaatctt
    10381 tgatttcccg caagacgaaa ggatcatttt tatcgtaaga ccaagaaact tttgggaaaa
    10441 agctaacagc taatccttgc ttgacaatag aacgtaatgt cgcaggatca tctgtcgtcg
    10501 aactgatcgt caattcgata cttttcgctt caagtgctgc atccagtgta tgacggaagg
    10561 cgttgctctt tgacagcatc aagatggggg tgcgttggat atcttctaat tgcagatgtt
    10621 cttttttagc aagaggatgt ttcttaggaa tggcgacata aacaggttct ttcatgatag
    10681 gaatattggt catgccaggc ttcatctccg aagtgatgta cagtacagga tcggtaatat
    10741 catctggtaa atgatgttgc atgatcgtta attggatatc aggatgcttt tccataaaaa
    10801 ttcggaccaa gttcggaata gaaacagagg ctacctctaa atacaatatg acggaagtaa
    10861 cgatcttctc attgaccgaa gacaataatt tgattccttc ttctaatgtg tctaatgtct
    10921 tgactgcata tggataaaat tcttctgcat aaacggtcgt ctcaatgttt ctgccgctat
    10981 ggtaaaacaa agggacacct aattcgtttt ccaaatgttt gatcgcacgg ctcaaggcag
    11041 gttgagaaat aaataattct ttggctgctt gggtaacatt ttttgtttcg aatacttttt
    11101 taaaatactg cagatgaagc aatttcataa ttatccatcc catccatacc tttttgttat
    11161 ggttttttct ttttttggca ttttttatta tagcagaaat tgactaagat agcagtggaa
    11221 aaagtaagtg ctgaggaggc gaggctcatg agtacaggtt tcttatttcc tggacaaggc
    11281 agtcagaagt tagggatgtt agcggatatc cctgaaatgt acatggaacg tttagaaaat
    11341 gtgacggggt atcggttagt tgataaagaa gaaaactatc aagatacggt ttttatccag
    11401 ctagcattac tgacaaaagc agtattttat ttagatgaaa tggaaaaaaa cggtattcag
    11461 cctgatattg cagcaggaca ttcgattggt gctttttgtg cagctgttgc ttgtcgatct
    11521 ttgagatttg agaatgcagc ggaactagtc tatcaccgcg cagtcttaat gaaagaagct
    11581 tatccaagcg gttatgcaat gggcgtagta gtaggtgtga cgagaagcga agctgaggaa
    11641 attgtagcaa aaacatttga tcctgaccat ccagtttatc tgtcaaatga aaattgtccg
    11701 atgcaacata cgttatctgg gagtatcgaa ggtttatccg ttacgttggc agaagccaaa
    11761 cggcaccaag cgcaaacagc gaagctgctg aaagtccctg tgccatctca ctgtctcttg
    11821 atgaatgata cggtcaagaa attcaagccg tatatgcagt ctgtccatct atctgatgct
    11881 agatgtttgt atataaaaaa tacggatgga agagccactc aggacgcaga agagattcgt
    11941 aaagatttgt tggaaaacct agctttccct gtgcagtgga accaaatgat ggacttggca
    12001 aaagaattag gaatggatct gacgattgaa tttccccccg gcaatacttt gacaaagctg
    12061 attcatacaa aatttggtgt agataaaggg atccgtacga tcaatctaga ccaacatggt
    12121 attgatgacg ccacgtttct atatcaaaaa tggagatgac taattatgga aaaaccaaac
    12181 cgcaactggg cttctaaacg cgaaaaaaaa gcgcagcgat tggaaaaaat cagcaacttg
    12241 ctcaatggca agtatgtaga aactgaaaaa atcgtagaag taatggaaaa actgattgct
    12301 cccggcgaca aagttgtatt agaaggcgac aatcaaaaac aagcaagttt tctttcagaa
    12361 agtcttgaaa aagtagatgc agaaaaagtg aatgatctgc atttgatcat gtctagtatc
    12421 tcacgaccag aacatttgaa tatttttgaa aaaggaatcg caagcaagat cgatttctct
    12481 tatgctggtg cacaaagctt gcgtgtcgcc caaatgattg aagacggcac aatgaaatta
    12541 ggtgatatcc atacttattt ggaactttat ggacgcttat tcatcgattt gattccaaat
    12601 gttgttttag tagctgcaga taaagcagat aaagacggca acttgtacac aggtttcaat
    12661 acggaagaaa caccaacaat catcgaagct gcagctttca aagatggtat cgtgatcgtt
    12721 caagttaacg aagttgtcga ttctttacca cgtgtagata tccctggtga ctgggtagac
    12781 gttgtcgtga aagcagataa accttatcaa ttagaagctt tattcacacg agatcctcaa
    12841 aacatcacag aattgcaaat tctaatggca atgatggcaa tcaaaggaat ctacgcagaa
    12901 cacggcgtac aatctttgaa tcacggtatt ggattcaata cagcagctat cgaattgtta
    12961 ctgccaactt atggtgaatc actagggtta aaagggaaaa tcgcgaagaa ctgggtattg
    13021 aacccacatc caacgatgat tccagccatc gaatcaggtt gggttgaaag catccatagt
    13081 tttggtggcg aagttggtat ggaaaaatat attgctgctc gcccagatgt cttttttgtc
    13141 ggtaaagacg gcacgatgcg cagtaaccga acattatcac aagctgcagg acaatatgcc
    13201 atcgatatgt ttatcggttc aaccttgcaa ttagattacg aaggaaactc ttctaccgta
    13261 acaaaaggac gtttatctgg ttttggcggt gcgcctaaca tgggacataa tcctggcggt
    13321 cgtcgtcatt ctacaccagc atggcaatca cttcgcgaca atgatgatcc attagggaaa
    13381 ggccaaaaat tagttgttca aatggttgaa acatatggtt caaataaaaa accagtcttt
    13441 gtcgaagaat tagatgcact agctgttcaa aaacaagcag gcttagccaa tgcaccagtg
    13501 atgatttata gcgaagatac tacacatatc gtgacagaag aaggaattgc ttatttgtac
    13561 aaagcaaaaa caaaagaaga acgacaagca gcaattgcag caattggcgg tgttacacct
    13621 cttggaatga ctagcacgaa agaatcacta gatagcttgc gtgcagccgg catcgtgaaa
    13681 ttaccagaag atctaggcat caaacgtagt gaagcgaaac gttcattatt agctgcacaa
    13741 accatcgatg atttgatcga atggtcagat ggcctgtatg aaccaccaat gaaattcaga
    13801 acttggtcat aaaattggcg agaaaaacct tttgtcgcca tttacccaga tggaagaaga
    13861 aagacgaata agcagaacgt gtatgctctg ttttacaaaa aggggagaga tccatggaac
    13921 aattagctta taaatatcca acgaaacagc cgatcaataa gaaaatccat gtaggagtgg
    13981 tcggttcagg agatttggaa atcttgatgt ttccaacaga aaaaacagaa tctactgtaa
    14041 aaatttgtac aggaagcgat ggcttcggcg aagtatggaa caatgtatta acgagatttt
    14101 ttgatcgtta tccaatttca gcagatatcg tgatcaatga cttcggtgct acaccaggag
    14161 ttgtgtacct acgattgacg caagcaatgg aggaactttc agatgaaaaa tagttttgta
    14221 gaattaaacg ccagagaacg agtgaacgct ctacttgaca atggacgtga attgattgat
    14281 ccattcgatc aaatcatcgc gccaagttta ccagcacaag gaatcgtccc tgaaagtgat
    14341 gacgggatcg ttgtcagccg tggcacgatc aatggcaaac aagcagtagt aatcgctatg
    14401 gaaggaaaat tccaaggtgg cggtatcggt gaagtttccg gtgcaaaaat cgttgctgca
    14461 cttgaacatg tgttagaaga aaataaaaaa ggaaatgaga tctttccagt cattgtacta
    14521 gatacaggtg gtgttcgttt gcaagaagca aactacggac tgttatctat ttcagaaatc
    14581 ggaaatgtaa tcattgctct aaaacaatat gtaccagtca tcggtttgat tccaggacgt
    14641 gtaggatcat ttggcggtat gtcgattact tcagcattaa tgagttattt aatcgcaaca
    14701 aaaaaagcga gagtcggttt gaatggacca gaagttattg aacaagaagc aggcgttcga
    14761 gaatttgatt ctagtgacaa agacttgatt tggaatacat taggatctcg tcaacgggta
    14821 gaatcaaaaa tcattgatga attagtgact gatagtgtag aagcaatcaa agctgctgtc
    14881 atcgcagcaa tggacgaacg aaaagacacg catcgcagtg aaagctcagc attttattta
    14941 tcattacttg attctttaga tctttcaaaa ccaatggcca ttgacgatta caatgaagca
    15001 attgctaacc atcaagcaaa atcaattgac ttaccagaag tagcagaagg aaatgaacca
    15061 gctgcagcaa gtgttggtta cgattggttt gcggcactaa ctggcatgaa aaatccaact
    15121 tcttctatta gtactgtgta ttatggtaaa tcaagtaaat tcatagaaga agccatcgtg
    15181 acatcaatcg tacctgatcc taaaaacccg atgtaccgtg tacgaaacgg tgaagttggt
    15241 ttagttgaag gtttccgcat gggacaaatt ttggatcacg tttacgaaga agataaagac
    15301 aaaaaagtga aacggccaat catcgttgtg atcgatgtac caagccaagc atacggctat
    15361 aacgaagaat tgatcggtat ccatgtggct ttggctaata gtgctgctgc ttatgcaaaa
    15421 ctccgtcaag ctggacatcc agttattgga ttgattgcag gaaatgctat ttcaggtgca
    15481 tttttagcac atggattaca atcaagccgc ttgattgctt taaacaataa agaaattacc
    15541 gtccaagcga tgtctaaaga aagtgctgca cgtgtgacaa aacgttcggt tgctgaaatc
    15601 gaagcagctg ctgaaaaagt tccagctatc gcttacgata tcaataatta tacaaaacta
    15661 ggagcgatct atcatttcct agaagatatc accgaccaag ctgcttcaga acaaaatgtc
    15721 agcaaagtca tcgaagcaat caatgaagcc attcaagatg tccgcaatac aaatgacacg
    15781 atgctgacaa atcgatacac aaacgaaaca gccaaaacat tcggacgtgt cgaaacaaat
    15841 aaagtccgtg ccaaaatgga cgaagaatgg gatgcataaa aaatgattca agcacatgat
    15901 attgtccttt ttgataaaca tgaaatagaa gggttcacct tgcctgaatg ggtcgttcta
    15961 actgaaaaga tgttcggaac agttcgtcgt gcgtcgacgg atcacgcaga aatactaccg
    16021 attggtttac gtggacctgc ccgcaatcag agatggtcaa cagaaatctc aaaacatgcc
    16081 gtcaaacaag tcattcatcc gtgggacatc atcgaacaag aatcgtatag acaagagaaa
    16141 atcatggatt atcctgttta tcagcaattt catgctgcta gaaacatatt atcaggatgt
    16201 aaatggggaa tcggcggcag cttaggattt gaattatcga ctgggattcc ggcagtaaaa
    16261 gaaaccagtg attttgattt gctgctgtac gcaaattcac cgattgaatt gccaattcag
    16321 gtaattcaat cgcatcctgc tttttttgag caattcgata cccaagtagt gactcggcaa
    16381 ggcggttttt cactaaaaga gtatttgaga gagccagaga aaaaaattct attgaaaaca
    16441 gtcgaaggac ctaaattaac caaagaactt tggtaataaa gaaaaagaga gagaaagaga
    16501 tgtttgaaaa caaaaaaatc aaaatcaacg taagtgactt ccagaaagta tcagctgtaa
    16561 cggctgttat gatgcaaacg atattgagct ttgctttggc aaacagccac agcgcaacaa
    16621 atacagcttt tcttggtacc ttttacgtca tcgttaaata cacagcacca atgtttattt
    16681 ttgcaattgt ttataatatg gtaaaaacaa gtcagcattt gtcttattgg gaatttttga
    16741 aagaaaagtt ttttgaacta gtcgttccgt atcttctatg gacgacggct tatctttggc
    16801 tatttccagc agtccaacaa caaactccgt atacggatac tgcaagcttt ttactgaaat
    16861 atgtcacagg tgatggagcg cctcatttat ggtataccgt tatgatgctg cagatccaat
    16921 tgttcatgcc gttttttgtt tggctcggtt acaaagtatt tgctaataaa aaatatgtat
    16981 ggccagtatt gattggttca acgattttat atgtcgcatg gtatctgttc tatcaaacac
    17041 aagtattgac tgggccttat catgacagct ggtacttatt agatcggttt gttgctagtt
    17101 tcatgattta tggggtagcc gcatttgttt atcacgaaaa agtctatcaa tatttggaca
    17161 gagtacgtta tcttttctta cctgttgcct tagttatcgc gttcttttct gtccgttcat
    17221 tgctcgcaca tccaggagac ttgagctttg cgaatgcacc ttacttgaat acgatccaaa
    17281 gtttatacag tttagtcatc atctttgctg tcttcatagg cgcttccaaa atgattgtaa
    17341 acgattcgcc aaaattgcca ttgttcaaat ggttgtctgt ttatgcttat cgtacgtatt
    17401 tagccaatgt atttgttttc caagtactgt tattattgtt taaagatagt tggctgcagt
    17461 taccttcagg agtcatgatt cttgtagctt atctaatgac ggcaagttgt gcatttgctt
    17521 taagctggtt acttcatatc atttgggtag ctatcaaaaa aggtttcagc aagtaatagt
    17581 aggaagaagg agtgagtgtc atgataaatg acgaacgaaa aaaagcagtg actcagcaac
    17641 tcgctgcgtt ggtagaggaa gcattgatcg cagaagtaac attaagtcca aaacctggat
    17701 tagtggatgc actggatgcg ggtgcacatt ccgatatgga ctatgcttta tttcttaagt
    17761 ctgctaagac gctaactcct ttttttgaag aaatggctca aatagcatgg catcatgcta
    17821 ttgatcagga gttaagagaa agaattgctg agattgggcg aaaagcggaa aaggcaatgc
    17881 tgattgctac aaatggcatc aatacccata aaggagcgat ttgggcaatg gggctattga
    17941 tcagtgtcat tgcacaaaaa atcagtatgg aacagccttt ttctttatcg aaaatacttg
    18001 atgatgtcag caagcttgct gcttttcctg atacaaaata tcgtcataaa aaaaccactc
    18061 atggtcatag ggtgaagcaa aaatatggcg taaatggtgc atatgaagaa gcgatattag
    18121 ggtatccgca tatcaggctt gcaattcaag cagctaagga gctagataat gattcatatg
    18181 tacagaaaca aatgcatatg ttgttagttt tgatgagttc gctagatgac acatgcgtat
    18241 tgcatcgcag tgatcagaaa acgttagtgg aaatgcaaaa acttgctcat gctgctagtc
    18301 aaagtgcttt accaaatcgt ccatttacag cactgttgca cttttgtcag gaaaaccaaa
    18361 tctctcctgg aggaagcgca gatctcttgt ctgcaagctt gttcatgctg aagatagagg
    18421 aattatggac tgccgacaca tacatttgtc cgatgttact caatgactaa ataagacaaa
    18481 attgctaaaa aaacagttta tgcatctggt tattgactct tccttttagc aaggctatca
    18541 taaaaatagt tttttgtaat aaaagataac gaggaagaca atgaaaaaaa tcaattattt
    18601 agcaatcatt ttgttagtgg gcctatgttt gtttgctctg ccgacccaag gattcgctgt
    18661 cgcgggtggt catggtggag gtacatctag cggtcgaagt tcgggcagag gttcatttgg
    18721 tggtcgttca tatgggggca gttattttgg cagtcgttct tacggcagag attcttatgg
    18781 gtattatggt ccaggtacag gtccttctag ttatgagcaa acgggatttc ttgcattagc
    18841 tgttttgtca gtaggagggg tttctgcttt ttctatcgtc aagaataaaa gacaaaagaa
    18901 aaggctgaaa gcggagatat tgtcccgcat gtcaggaacg gctaaagaaa agaaagcaca
    18961 gtttctggaa atccaaaaga tattcatgaa gatccaatcc gcttgggaag aagaaactcc
    19021 tgaaaaagcc agaagctgtt atacagacaa gctgtttgcc gaacatcaga aagttctgca
    19081 aaaaaacaaa gcagacggtg taagaaatca tactaaaaaa ataactattc aggaagtagg
    19141 aaattatcga cagatccacg aaaatagttt tgccatccga attgatttca gatgctgtga
    19201 ttattcagtc gatcgaaaag atgggcgatt gatctcagga agtaagacac aacgacagta
    19261 tttttctcag atatggtatt ttgatttttc tgagaaagaa aaaagatggc aagccgattt
    19321 tattcagccg attatgctgg attgacagga aatatttatg aacggagttg tgacaaaagc
    19381 cttgtcgcag ctcctttttc tgaataaacg gtgtgccaga gatagcctat cggcaataag
    19441 gcacgatttt gtaaaatatg ggaagcgatt tttcaaaatc gcttcttatc gctcaaggct
    19501 gaacatctct gtcacaacct ctccactaaa tggtgtttaa aagcttgcat ctgcgataat
    19561 aagaacaacc aaacgaaaaa taggaagcac tattttagtt tagttgttct tattacttga
    19621 tgcaggacag ctttttcaca acctcttttt tgtatagatg ggcaaaattt ttgtaataat
    19681 aggcgtatgt ctttttcgtt gaggagatga aaaagcatat ggcttatttt ttgtttgctt
    19741 tgcttacttt ctttccactt caagtggcag aaatatctac tttttattat gtaagcggaa
    19801 ccatatactt gaaatcagaa ggagatcatt tctatgaaaa caagaacaat tgaaatactt
    19861 cacagaatca tgacagccca atatccagta aaagcaaaac atctagcaag tgagttcaat
    19921 gtcagtcagc ggacgatccg tcaggaagtt cttgaagcga atatctggtt gagcagtaaa
    19981 aagcttccgg agatccgtac aattcgcaac aaaggttttt tgttgaagct ggaaaaggaa
    20041 aagcaagctc gattagaaac tgaaataaaa gatgtgaaag acggcttttt gaatcggcgc
    20101 gaacgtattt ttgatctagt tttagccgtt gcttacagcc gaatcccgat ccatctaaac
    20161 aaaaaagaag aagaatttca aatctctaaa agtacattag atgaagatat gagacggtta
    20221 cgagcaacac tggtcagtta tgggatagag atcgtcagtt atggaaagca aggactggtt
    20281 tataaaggtt cagaacgatc tatccgtacg atgatctatg attttatcaa tcagaatctg
    20341 ggaatgaccg acttctttat gaatcaagat gcacaattaa caccggctca aaaaatcttt
    20401 ctccattatt ttcctttggt ggaaatcaaa aaaatacagg agatctattc caataagttg
    20461 ttgaaacaag aagatgatat ttataaaaaa caaatcctgc tttttacatt gatctggatc
    20521 cagcgaatca ggaaacatga atttatctct gccattaatt ggaaaaatac agaaataaaa
    20581 gacagtagct tttctgcatt tattgaccac atgatcgagg aatttcaatt ggacaatgtc
    20641 ccgcaagtag aaagaaatta tcttcgtttc actattgaga cgttcaatgc tagagatatc
    20701 tccaattcaa tcgagtgggt acaagctcaa ttactaacga tccaattgat ccaatttgta
    20761 gagaacgaga cacacgtacc tttccatcta aaggaagaag ctttattcga aaatctctat
    20821 aagcacatgg ctgcactgat tgtaagaatc aagaatcata tccaagtcat gaatccattg
    20881 aaagaaaaca tccgaacaaa ttatttccca atctaccgcg cagtcactca ttttgttcct
    20941 acgatcgaag aagtaattgg tggcaagata ctggaggacg agatagcttt tcttgtcatc
    21001 cacttttcga cgatcgccag tgtaatcaag cgagacttga attatgttta taaatcagtc
    21061 gttgtctgta accatgggat ggctactgga aatctgttag cagagaatct gaaagaaaag
    21121 tttcctcaga tcgagattac tgcagtttta agttcaaaag aaatcgaatt agtagataaa
    21181 ttggatgtca atctggtttt cagcaccttt caattgaatt atcgaaataa gccgctttta
    21241 gttgtcgatc cgattttaac tgagacgaat atcttggtta tagaagactt tttgaaaaga
    21301 aatgaagaac tacagcggtt agagcctaac agtcatgaat cgacggagtt attcactcaa
    21361 ataatagatg tcatgaaaga aagtggtggc cgagtagatc gaatcatcta tggcaagtta
    21421 gaaaaattat tcgaaacaaa caatttagaa atcaacaaaa gggagatcca gcctatgtta
    21481 aaagatattt tgacggacag caatatcatg atcaaagaaa aagccactac ttgggaggaa
    21541 tcgattgaac tagctgctag accattggtt aaagaaaaca ttgtcgaaga gcgctatgtc
    21601 gaagcgatga ttcgtgcagt gaatgattac ggaccgtata tcgtgattgg caaacacatg
    21661 gcactagccc atgcccgacc agaagatggg gtcaataaat taggagtcag cgtagctacg
    21721 attgagcaac caatcgattt cggtaatcct gaaatggatc cagtaaagat tattttttgt
    21781 ttggcagcag tagactccta ctcgcatctg aacatcatga aagaactaat tgaattgatc
    21841 aacaacgaag agaagttgga tcgattgatt gaatgcacaa atatcgaaga tttcaaacaa
    21901 ctgctttttt cagtagttga gaaataataa atgatacggg ggagaacaaa gatgaacaaa
    21961 ttgaacattt tattcgtatg cggtgcaggt ttaggaagta gttttgcagc acagatgtct
    22021 gctgaggatg ttttgaacaa attaggagta gaagccaaac tggaccattg tgatatttct
    22081 tccgcagttt ccatgaaacc agatgtgatc atcacagcag aaaattttcg ttcgcagttc
    22141 gaaaagttcg cagttgatcc taaaacggcg atgatctatt tgaaaaatat tgtttcaaaa
    22201 aatgaaattg aagaaaaaat caccccagtt ctgcaagata agggagttat ctaaatacaa
    22261 aaagaaaaga gggtaaaaa
//
LOCUS       DADQCX010000043        22276 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.043, whole genome shotgun sequence.
ACCESSION   DADQCX010000043 DADQCX010000000
VERSION     DADQCX010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.043"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..237
                     /locus_tag="J8R83_001521"
     CDS             <1..237
                     /locus_tag="J8R83_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9574652.1"
                     /translation="IYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRKVNQTFISSV
                     SNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(308..1618)
                     /locus_tag="J8R83_001522"
     CDS             complement(308..1618)
                     /locus_tag="J8R83_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAZ9574653.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1630..3048)
                     /locus_tag="J8R83_001523"
     CDS             complement(1630..3048)
                     /locus_tag="J8R83_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9574654.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3288..4856)
                     /locus_tag="J8R83_001524"
     CDS             complement(3288..4856)
                     /locus_tag="J8R83_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAZ9574655.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4860..5141)
                     /locus_tag="J8R83_001525"
     CDS             complement(4860..5141)
                     /locus_tag="J8R83_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAZ9574656.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(5138..6061)
                     /locus_tag="J8R83_001526"
     CDS             complement(5138..6061)
                     /locus_tag="J8R83_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAZ9574657.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6058..6936)
                     /locus_tag="J8R83_001527"
     CDS             complement(6058..6936)
                     /locus_tag="J8R83_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAZ9574658.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6923..8260)
                     /locus_tag="J8R83_001528"
     CDS             complement(6923..8260)
                     /locus_tag="J8R83_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAZ9574659.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8263..9366)
                     /locus_tag="J8R83_001529"
     CDS             complement(8263..9366)
                     /locus_tag="J8R83_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAZ9574660.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASSSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9440..10948)
                     /locus_tag="J8R83_001530"
     CDS             complement(9440..10948)
                     /locus_tag="J8R83_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9574661.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10914..11606)
                     /locus_tag="J8R83_001531"
     CDS             complement(10914..11606)
                     /locus_tag="J8R83_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAZ9574662.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11628..12602)
                     /locus_tag="J8R83_001532"
     CDS             complement(11628..12602)
                     /locus_tag="J8R83_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574663.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12902..13774
                     /locus_tag="J8R83_001533"
     CDS             12902..13774
                     /locus_tag="J8R83_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574664.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14356..16554)
                     /locus_tag="J8R83_001534"
     CDS             complement(14356..16554)
                     /locus_tag="J8R83_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9574665.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16786..17778
                     /locus_tag="J8R83_001535"
     CDS             16786..17778
                     /locus_tag="J8R83_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9574666.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17838..19259
                     /locus_tag="J8R83_001536"
     CDS             17838..19259
                     /locus_tag="J8R83_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAZ9574667.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19252..20751
                     /locus_tag="J8R83_001537"
     CDS             19252..20751
                     /locus_tag="J8R83_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAZ9574668.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20790..22184
                     /gene="uxaC"
                     /locus_tag="J8R83_001538"
     CDS             20790..22184
                     /gene="uxaC"
                     /locus_tag="J8R83_001538"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAZ9574669.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRSCGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6758 a         4540 c         3860 g         7118 t
ORIGIN      
        1 atatattttg cggaccctgg aacaccttct caacgcccat taaacgagaa ttctaacggg
       61 attctgcgtc gtaatggact gccgaaatca atggatttta gaaaagtgaa tcagacattt
      121 atttccagtg tcagcaatca acgtaatcat attccaagaa aatcattgaa ttacagaaca
      181 ccaatcgaaa tatttttgag ctatgtacaa gaagcatttt attctagctt aatttgacaa
      241 atcatatatc attaaaaaaa ataaaggtca agctaaaata ttatttaagc ttgaccttat
      301 tataatttca acgattgtca aaagtattgt ttgcagctgt gttgccagtt tctatagata
      361 aatcacagct tttgaaacat aagttttgta ctgcttcgat tcgcccgaat tcttttgcag
      421 ttatttggca atgagaaaag cagacatctt ctataggctt ttcaggaaat gctactaaat
      481 caaaagctcg ggaaggaagt gagtaacctg gagaaaggca tgcctgtacg tttttgatgt
      541 gtatgtcttt gactttcgtc atttgctttg attcaggtat ttcttcagcc actgcttgcc
      601 aactttctgg catttgagca aggtcattgc tattttttct attgtattca ttatgccagt
      661 ccattatcca agaaaaagga aattgtacat caatcatatt cagattttct accctgatat
      721 tttcgatcac tccccctctt tcttttgaag atttcattcg aataccacag tctgactgaa
      781 aaaaattgat atcgtgaata tatacgtcac taactccagc actaacttcg ctaccaatag
      841 ttacaccgta tcctgaacgg attttacatc tagcaacctc gattcttgat gattttcgat
      901 tgactcttgc accattgcca tctctgccag acttaatagc aatacaatca tcaccacagg
      961 ccaaatcaca ttcatagaca cgcacatttg ttgaagaatc aatatcaatc ccatctgtac
     1021 ttggtccatc attgttgcgg atgattactt tttctactaa tacatcgtta gaataagtga
     1081 tttgcaagtt ccaaaaacct gatttctgaa aaatcaaatc acgaacaaca acatgttctg
     1141 catgatacag taaacaagcg cgtggacgtt taatagcata atccgcaatc caacgaagtc
     1201 ccttttgatc gtattcagct cttgtcccgc ttttttgatc ttttccccaa tacagctccc
     1261 accaatggtc tccttgaccg tcgattattc cttttccttc tataagaata tctttcgccg
     1321 agagaacatt caaaatcgct gctggccatt tcatttctac gccggctact cgtgtatcga
     1381 tttctggaaa tgcttcgata tctgttctcc ccttgaggac tgcaccttct tcaaagataa
     1441 gatgactctt atcttttaaa aaaagggctc cgactaaata aatgcctttt ggaataaata
     1501 caggtaagtg ttctttcgca ccttgatcga ttgctttttg cagtattatt gtatcatctt
     1561 gttgagtgtc gtttgtttta aagttcaaag cattgataat cccttttttt gtccgcaata
     1621 cgtttctccc tatctttcat tgattttttt caattcttca ccaataaata cagtttttga
     1681 acgattcagt gggtaaccta ctagcaaaat gattgcggat acaaataagc agaatgctgg
     1741 taacaagttt gccatcgtat aaatcctttc ttgtactaaa actgattgga tggctccacc
     1801 tgttgtagac gattggtaac caatgagtgc cagcataaat ccgcctaccg ctcctgcaca
     1861 tgcttgtcct acttttctcg caaaagaatt tactccatat actgttccat cttctcttaa
     1921 gcctgtctta tattgatgat aatcaatcac gtcagtaatg aatgcccaga ccatcaaatt
     1981 gaataaacca gatcctaaag tagcgataaa taaaagaatc agatataccc atgcatttgt
     2041 tatatgaagg aaatacatca gcaagtacat acatgaagaa gcaagtaacg caaatacgct
     2101 tgcttccttt ttaccaaata attttgtcag ctttgtagca aatggtgcta aaactactac
     2161 tgttccgtaa gtaaataaaa gagcaacaga cattgcttgt ttattatgga agtaatcatt
     2221 gaataaataa gtcatattcg tcccagctaa aatctgattg atcacaatga aaatgtcaac
     2281 aatgactaaa ataatcagtg ctcgattagc taacaaacct tttaccaact gagaagcaga
     2341 tactttttcg tttttgacaa ctcttactct ttcagtagtc aatttacaag ttaacatata
     2401 tgcgacaaat gctattgcag cacatccgat tgaaatccaa aaaaaatgat tccctgaaac
     2461 gacttgttgt ccactcttgt tatgggtata cattaaaatc ggaatgaaga atcctgtagt
     2521 tgatccgcca atcgcagaac caatgcttcg gaacgtggac aacgaggtgc ggtcattagg
     2581 atttgagcta attgctgctg ccattgctcc atacgggata ttgattgttg agagaaaaat
     2641 cccataaaca atgtatgaaa caaaaatata agcaatcttc accgtcattg gaagatgttg
     2701 gacgaatggc aaaaacaaaa tgacagtcac taagcaaaat ggatacttca tttttctgat
     2761 ccaaggaata aatcggccag tttctgttaa ctctgagaca tcacataatc ttccaaccat
     2821 cacatcagca aacgcatcca aaattctcga aatcaagaat aacgtaccta cgattgcccc
     2881 tgaaacgcca agaacattcg tataataaat catcaagaaa ctattgacta aacctaaaat
     2941 aaaacagtta cctagatcac cgaacatgta gcctatctta tcggaaatcc caaattcctt
     3001 tttttctttt tttactgtat ttgctgtaac agcattttgt gaaagcattt gaattcctcc
     3061 tacctcttct agtaaacgtt ttcaaaatta taactctttt tttcttgttt ttatattcac
     3121 aatgttggct ttttattgca ttatcttgac agataaaaaa caaaaaataa tctaaaaaca
     3181 ttgatgcata agattgataa ctttttttac ataacaatat atacaaacaa aaaaattcac
     3241 taactagtga aaataagtta gtgaacctca tttattaaag aattaaatta cagatgatct
     3301 tttccatcat acttgaaaaa ctcaaaatca gcataacttc ctcttttttt atttagatca
     3361 tgcactgcta tcccgataaa atttccagta aaccctcctg agagtataca catgtttttt
     3421 tgcggaccta ctttcttcca ttcttcagtt gatacgtctt tcaaatgaaa ctgtgctgtc
     3481 tctttcttta cagtgacttt caaaaaagtc ttcttttctg tgagtggaat cgtccaatct
     3541 tctatttgtg ctactccgtt ttctgattct atcatacgta ggcattttcc cttgtcctca
     3601 ttccaagtaa cataacaata aatataattg gattcattta agtacagtac cagtccagcc
     3661 atctgattaa aattattagg catgtattca aatgctgtct ccgcatcaaa agtaaaatcc
     3721 gtttgccgaa tagctaacaa atgatgttcg aaggtagatt gaagagattc accggaaatc
     3781 agacgtaaaa aacctggtct acattttgta tcacaccaat cagcatttgg caaaatgcgt
     3841 ctggcattcc agttcttctt tagctctcct tcaaatgtat ccataaactg atgatctttt
     3901 tcttgttgta cctcttcatt tgtctcaatc attatttctt ccatcggagt tgtctggcta
     3961 tctttaagtc ttaaccaatc gtcggacgtc caatacactt cttgaatagc ggtttctctt
     4021 cccaaaatag ccgcaccgtt taatggtctg gtacaaagat atgtcatgta ccatcttcct
     4081 gacggggttt gtactaagct cccatgtcct gtacattgca atgtagaagc aggtttgtca
     4141 ctagctgtca gcataggaaa accaggatca agctcgtaag gaccagtaat attctttgct
     4201 cggcaaactg taactgaatg tcctcttcct gtaccgcctt ctgccgtcat caaataataa
     4261 tacccgttac gaaaatacaa atgtggtgcc tccgttttcg ctaattctgt acctgcaaat
     4321 attttataga tgggaccatc aagcttcttc ttctctgcat catattcttg taatacgata
     4381 ccgctggatt tattcggtgt gtccagacga taatcccata gttcattgac aagccatttt
     4441 tttcccgttt caagatcatg gaacaaagaa ggatcaaagc cgttactatt taaataaatt
     4501 ggttcggacc aaggacctgt gatctcagat gcagtgatca aataattgtg gacatcttta
     4561 aacggacggc ctgcactttt gacatctgtg taaacaagat aaaacaatcc atcagcataa
     4621 ctgatctgtg gcgcccatat acttccattt gtaggatttc cttgcaaaga tacttgagtg
     4681 gtcaaaatat ccgttgtatg tgaccagttg actaaatttt tcgactcata tactcggatt
     4741 cctggaagcc attcaaaaga ggagacaata atgtaatacc gctctttcac tcttaatata
     4801 ttaggatctg gattgaatcc tcttaaaata ggatttttca ctttgatagt ctgcatgatt
     4861 caggctcctt ttctcattct tactcgatat aaactgaatg ccccagctgc taaaaaagca
     4921 agtgaaataa acaacacaac ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta
     4981 ttttctaaag acaaagttga atgatctaca gcaagcgact gataactttt tttaaactct
     5041 gacgcagaca tattacttaa agtaactgct aacccgccaa agaaaatcaa agatagactg
     5101 ccaccgacca ttcctagcaa tagttcccat tttcttttca tttctgaacc ccctgctttt
     5161 ctaaatgtat ccattcaggt cttttgatcg atgtttcata attgttatta cgttcagaga
     5221 atttgacagt ctgttcattt ttcttgtcat cccaattatc ccaaccagtt gggtgaacat
     5281 gcccacctat cttacacgct tcaaataaga catttgcata cggacgccac ggtcttccta
     5341 aatagacgtt tctagtatca ggttctgcag tcaaggtaca gctttcaaaa cgataccctg
     5401 ttttttgatt tttcggcgta gatgctgctg tgatgtatcc aggattttta ctggctaagc
     5461 tatggatatg acactgatga aaaacggcat ctgccccacc aaatatgaaa tccaccgttc
     5521 cttcaatcca gcaatattca taggtctgac gacaatactc aggattggca gaagccggtg
     5581 tacaaaaagg agtaccatct ttttgcaaat caggcaacgg acccgtgcat aaggtatcct
     5641 gataaccaga tagtcgacag ttttttaaag atacgcgatc tcctgaattg aataaagcaa
     5701 cagcctgtcc taccttttct cctggacctg ctgtattttc gatgtgaaga ttttctaata
     5761 cgacattcga tccttctaag aaaaaagtag cacttcggaa agtccctaac tggctaccgt
     5821 caagatactc ctgttttgca aaacgattac cggagataac tactgttcct gctcccacaa
     5881 gtttaaaatt ggataatctg ctttctatat attcatcata tcttccttct tttactatca
     5941 agacctttgg atggctatcc ggcaggcctg ccaaataatc gattccttct tggatagttt
     6001 caaaatccgt cggggtatct atagcattct ttccaattat cagtttgtct ttcatcctca
     6061 taaatgctcc cttatgaatt gtttccaaat atttctcatt tcttgtgttt ccatatgacc
     6121 gcctgttaaa gaaaaagaag aaaagttttc tggactaccc attgattgat actttttgtc
     6181 cagccctttt ctcagcttca gtacgccttc gtccaagcac atcgtatcgt tttttccaac
     6241 taagctaaga cgagggcgcg gagcgatttt ttcttggatt gctaacgttg tataagctgt
     6301 caatagattt ggcacatagt aataaaaccc atgatgatct aggcggcgat gtagcaaaag
     6361 tgtttcgatg tccacctgtg ccgctagatc aatacaaact ttgacacgag aatccaatgc
     6421 tgtcacccac cagcttaata agcctcccat agaaagacca atcgttgcga gccgttgagt
     6481 atctgtgtct tcccttgtct ccaaataatc gatcaagctg atcacatcat aaatacgcat
     6541 tccccataac gtttttcctg ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc
     6601 tccgcgttct tcaaatcccc aagcatcaat cgaccaaaca gcatatccca ttcctgtcag
     6661 tacttctgca aaagatggag aagctaagta aggagcacca tggatcaatt cacttttccc
     6721 gactgaaaaa tctccgccgt gagaatgcag gtaaaggacc gtcggaaacg gtccttcttt
     6781 ttctggataa gcatagaggg ctggtactgt ttccaattca tttaagtaca attgatagta
     6841 ttcaagcata aaaccgtttt gtttttctcg gtataatcgt tttccactag gggtatgtct
     6901 gctagatgga gcacctaaaa aatcattcaa ctgcataagc aaagttttta cgaacaacca
     6961 gttcatccat attttctgat tgatttgatt ggaatttctc aatactgatt tctttagtat
     7021 tttctaatag aaatgctggt ccctcgtgat tttcaatcga catctggtta aaggaaacct
     7081 tacccgcaaa gccaatataa aatccttgtc tgctcatttc ctctattcct gtcatcatag
     7141 caggaacacc gggaactgca tcttgggcca tcgagacatc gatattgtca aatgtgattt
     7201 cttgtatgaa ttgttccgct aatccataaa taaaacctgc agaagcatgg acattccttg
     7261 ccgtgatatt cgaaaaatgg atccttctga atgctgatgt ccgttcatct atcggataag
     7321 cctttttttc ccatacatac ggttctttcc ctcgcggacc acagaaataa taaagattca
     7381 gtataaatgg acacatcaca ttatccatga ctatattgga tactcgaata tcttcaacga
     7441 tcccgcctcg acctcgtcta gatttcaatc gtattcctcg atcagtttct tggaagatac
     7501 aatttgaaat ggtaatatta cgaatactac cactcatttc acttcctaat acgacaccgc
     7561 catgtccatg gaccatcgtg caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt
     7621 acgtatcttc agtccctgcc ttgattgcaa tacagtcatc tcccacgtca atatggcaat
     7681 tactaatacg cacatttttg catgattctg gatcaattcc gtctgtattt ggtgaatccg
     7741 ctgggttcaa gatcgtcaag ttatcaaacg ttgcattact gcaaagaatc gggttgatcg
     7801 tccaacttgg tgactggatc aatttaatat ctttcacagt aattcgatga cagttatgga
     7861 aactcatcaa tttaggacga ggataagcga gattatctgg ttcatttcta aaagtatgcc
     7921 accatttttt tccatttcca tctaatgtac cgaaaccagt gacagagatg ttctctacat
     7981 tttgagcata gatacaggaa gcataaactt ttcgatggac tccttcccaa cgtgaatgaa
     8041 caacaggata atcttttgga tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa
     8101 gttcgacatt gctttttaaa aataaagctc ctgttagaaa ttcacctgct ggaacaacta
     8161 cggtcccgcc tccgtcactt gctgcagcat caatggcttg ttgtattgct tcagtattca
     8221 attcatcaat tgatgcgcca aatgtcaaaa tatcatacat atttataatg cctccacttc
     8281 aatcaatgct tgcaagaatg caccaacgcc tttttgatca ttacaaataa ttggttcact
     8341 gatgtagtaa gcatatgaac catctcgctg atctgctccg cctaaccctg ctacttgaca
     8401 gtttttattc aagttcagcc agccttcttt tgtttccaga acaaattcat caagtaatcc
     8461 ttgatgtgat ttcttcactt gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat
     8521 tcctttagcc attgcgtaaa caaacatact actgctggaa gcttccagat aatttccttt
     8581 ccgttttgtt tctgttgtta cttgatacca tgtcccgctg ttttcttctt gatatggaag
     8641 taatgcagcc agtgtctttt ctagaatttc tttcagcaaa gaacaatctg tttcttcatg
     8701 aagtaattca taggtatctg ctgcagccat caaataccag ccaatcgatc ggctccaaaa
     8761 atgatgggat agacctgttt ttggatcagc ccatggttgg accttctttt catcccatgc
     8821 atgaatcagc aaatttgttt ttggatcgaa tagatgttta taactgattt caaactgtct
     8881 caaaacatct tggtaatctt tttcttcact aaaattctgg ataaattcag cataaaaagg
     8941 agaacccata tataagccat ccaaccaaat ttgataagga taaatttctt tatgccaaaa
     9001 agctccttcg gatgtgcgtg gatggtttgc caactgctgg gaaaggagtt ctgctgcttt
     9061 tttatatttt tcttcgcctg tttctttgta caataaaaag aaaagctttc ctgtatttac
     9121 atggtcgata ttgtattctt caacgctgta gccacggatc gttccatctt cttgcacgaa
     9181 atagtcgata ttgtctttta tgaaatcaaa ataaattttt tcttgggttc gttcccaaag
     9241 taattggaac cctttaagta cgacgccata gtcataagac cattttcctt tataccactt
     9301 ttcttcatat aagcgaggtg ttctttccat gatacttttt gctaatttct ttgaccagtt
     9361 ttccattatt tgctctcctt taaaaattaa aataggattt gggacaaata ccaagaagta
     9421 tttgtcccaa tcgtctatat tactgtgccg ctgctttgta tgcttcctcg tactcttgtg
     9481 tgattcgatc gcctccttgt gctttccagt cttctacagc ttttttgaat ccatcttcgt
     9541 caagctgtcc catgatgtat tgcaccgtag catcaatgac gattttttca atttctgatc
     9601 ctacttcatt gttcgtcggt gaatccaatg gcacagaagg atccattaca gcaaattctt
     9661 cattttcttt gatcaattga ttagagaatt ctttttcagg gtctgtatct ttgaaagaga
     9721 acgtcacttc actaggacga gagcttgata acggttgcac ctcttgttgc caaagatcca
     9781 tatcgataaa ttcgatagaa ccatcatcat tcaattcata atgcgttcct tcgataccgc
     9841 cagtcatcaa tttatacaca tcttcttcta aaagatcatc aacaaattga agtaatttct
     9901 tcaattgtgc ttcgtctttt acttgagatt tgggaaatgc tagcaagccg ccaataccat
     9961 ttccttctga ccaaacatga taaccgccgc cttcaccatc tgagatcttg tttacaggca
    10021 ctaattccat atcatcttga ataccttgac ccatcgtctt cagattcttg atatccacca
    10081 ttccagtgta gattccagtt cttccttgtg caaattgttc ttgctgatca gtcttttggg
    10141 taactgcaaa gtcttgtgcc aaatagccat tctcaaatag atctcttgaa aaattcaaag
    10201 ctttcatata ctcttctgta tcaaattctg gagtgaattt gccattatcg tctacagccc
    10261 agccatttgg tgctccaaaa taagaagtga aaagtttaaa gctggtataa cgaatatcac
    10321 taggcgcacg atcgccaaaa ccaactgtgt cgtccacacc atttccatca ggatcgtttt
    10381 ctgtaaattg tttagctact tcataaagct catccatggt agttggaaca tctagtccta
    10441 gattatccaa ccagtctttt cgaatgacta agccagcacg agcgtagtct ttttgtatcg
    10501 gtacgccgta caaggcaccg tcgatactcg cagcttcgat tctatcttca gaaatttgac
    10561 ttaaattttt atagtctttt aaatattctg atacatccca gaatacgcct gattttaacg
    10621 cattgcggac agaagagttt ttcaacatcg caatttgaag tgtaacgata tctcctagtt
    10681 catcagaagc caatgcagtt gttaatcttt cttcttttga agcatcagga atccagttga
    10741 atgtcagttc cgtatcggtt ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg
    10801 aagcatgatg caaaatattt aaccaagtga ttttagcttt tccatcttct gtctctgaag
    10861 aactgttact tgaactgctg ccgcatgcgg caagtgctag aattcctgca aaactaagac
    10921 ctaattttac gagcgttgct tttttcataa attttctcct tcactgtttt aataatattt
    10981 ttgttttctt ctgttttttc tgtatatgag ttcttccatt ccaaatggca aaatatagaa
    11041 tttgctgtcc acgtgactgc ggaaaagaag agactgccac cgataaaggt taaaacacct
    11101 ggcattgttt ggatgatcat cagataaatc cctaccatac ttaatatcaa cactaatgag
    11161 taatgaagat gtgagaatcc gaataaaaat gccattttca ttttgaaaaa atatcctttc
    11221 caatcataat gagccatgat tgggaaaata tagagtgctg agagcacata tatgaacgca
    11281 gcaatataca aagcgatcct aagataccaa ttgtgtatga aagaaagatc cacaagtaaa
    11341 acaatcccga tggcgccata tatccagctc atcagcaagg tttcacgata gttttcttta
    11401 aaatatgtga agtacgtttt cgtcaaagga aacgtttctt ttgagcgcag ccattttcta
    11461 atcactgcaa ccatcgcata cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg
    11521 actaaaccgc cccacagaaa attcaaataa accaactgta aaatacgatt tagccttccg
    11581 tttattttat ctaatgactg cagcatatct ttccctctct ttctatctta gtaaacgccg
    11641 tcttctccta gctttttggc aatcttatta gctaaaatta ccataaacaa tcctacgacc
    11701 cctttaaaca atcccattgc tgtactgaaa cttaactgtc cattcttcaa tccagctgta
    11761 taaatatagg tgtcgaaaat ttctgcaacg cttcgattca atgaattcaa taacaagtac
    11821 atatgctcga accctaagtc taatgtctga ccgattttta gaatcagcaa ggtaatgatt
    11881 actggacgaa ttgccggcaa tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc
    11941 atttctgcag cttcatacaa ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc
    12001 gtagaccagc ccaactcttt ccagatcact tgtccgatat atactgtgcg tgtccattca
    12061 ggggatgtta gaaaactgat tttttcaaat cccattgttg caaggaattc attcaatacc
    12121 cctccgtcaa cattcaaaaa tacataagta atcgaaacaa tgattaccca agacatgaag
    12181 tgagggatgt aaatgatcgt ttgaatcccg tttttcaatc gtttgttcgt tacttcattt
    12241 aatagtaaag acaaaatgat tggcatcgga aaaaacacga agatatttaa tccgaacaag
    12301 atcaacgtat ttcttaataa tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt
    12361 ttgaaaccga cccaaggact tcccattatt cctaaaaatg gttgataatc ttgaaaagca
    12421 ataacgagtc cccccatagg aagataccta aaaatcaaga aataaaggac tcccggcaga
    12481 atcatcacat ataaaaattt attcgttttg attcctgcaa ttattttttt tcgtcttctg
    12541 agcttttctt cttttttcga tagcgtcagt tgaaatggtt cttgtttctt tacactttcc
    12601 ataagcccct ccttagtttt gtgaatgttt gctgcttatg acttcatgat agataactat
    12661 ctgaattacg tatataatca tttttatcgt aagtaaaaac gcttacatag caatgatttt
    12721 tgtgctatac aaaacgataa agtgtatttt ttcacaaata aactacgcat agcaaacctt
    12781 ctattttttt ctatctgaca cttagcatag gaaatgatta tatacgtaat ctttcaccga
    12841 tgataaattg aacatataga aacagaaaca tttaatttat tttgaggagg agcctatcta
    12901 tatgaaaaag aaagtctcta taggagaaag aagttttaca cttttcaaca atacgtttct
    12961 aattttgcta gctttgatct gtatcgttcc ttttttaaat atcatcgcta catcttttgc
    13021 ttctacacaa gaagtcgtcg cgaaaaagtt tatccttttt cctactacct tttctttaga
    13081 cgcgtatcgc tacattcttt ctacgccgac catttttaga gcacttgctg tttcgattgg
    13141 tgttacaggt gtcggaacga tcgtcagtat gtgtgcaact tcactgatgg cctacggtct
    13201 ttccagaaag tatttgtttg gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt
    13261 gttcagcggg gggatgattc caacgttctt agttgttcgt tctctagggc tggtcaattc
    13321 ttactgggcc atgatcctgc ctgtggctgt taatgcaatg aatatgatca ttatgagaaa
    13381 ctttttccaa gccttgccgg atagtttgga agaatcagca aaaatggatg gttgcacaga
    13441 ttttggtgta tttttcaaaa ttatgctgcc attagcttta ccgtctattg ctactatctc
    13501 gcttttttat gctgttactt actggaacac ttatatgact gctattttgt atatcaacga
    13561 ttcatctaaa tggccgatac agattctttt acgccaaatc gtcattgtat caagtgggat
    13621 gcaagcagaa agtagtgccg ttgatgtgat tccaccagca caaacagtta aaatggctgt
    13681 tatcgttatt gcaacagtgc ctatgctgat tgtttatcct tttgttcaga aatattttgt
    13741 caaaggagca ctcgtaggtt ctgtcaaagg gtgattatgt actgaacgca aaatggtagt
    13801 tgtgtcagaa gtggtcagct tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa
    13861 tttttgtgaa atttcggctt atttttcgaa gaatctactc ctggaacacc gtgtatcaga
    13921 ggttgtgaaa gagacgttca gccttgagcg atgataaaaa ctctcacaaa cattgcgacg
    13981 agtaacccac aggagcaata agaagcgatt ttgaaaaata gcttcccata tttcacaaaa
    14041 ttatgcctta ttgtcgatag cctgtctctt gaacgccatt tattcgtaaa aaagaactgt
    14101 gacaagactt ttgtcacagt tctttttgcg tgcttagcct tgaaatttaa ctatccataa
    14161 atacaaatac tagggttatt ctaacttctt ttattgcttg aatcagtcca caagaaaaac
    14221 agcctcttga ttaaacggcg tttatcttgt tgattctgcg gcaataaaat cagccagcag
    14281 caaaacatga agtgctgttt tttgctgtcc tcttttattg cttgaatcag atcacaagaa
    14341 aaacagcctc ttgattcaca aatatttttt tcgatattct cccggcgtaa tcgattcctt
    14401 ctttttaaag aaacgaataa aattttgcgg atttcgatat tgcaatcttt ctgcaatctc
    14461 ttttacggag aggttagtct ctttcaacca tttttttgct acctctaaac gatgattttg
    14521 aacaaaatca ccaaattttt ctcctgtttc ctttttaaat acattactta aatagttagg
    14581 gttataatgc aacctatcag cgatcacatc taaagacaga tcacgatcat attctgtgta
    14641 gacgatatgc ataatattct ccgacaaatt tttaaattca tgatcagtga ttgcttgaga
    14701 gcattctgtg attggcagaa ctaattgttc taaaacaagt ttttctagtt ctttgggatg
    14761 ataattgttc agtgctttta cataaatttg tttcatgtta tcaaagtttt ttgaatctac
    14821 tcccaataac tgtcctaatt gaacgagttc attgatcaag cggaccgaaa ctacttcccg
    14881 actcaaagga tttttatttt gtgcaaacaa tgcatcaatc aattcatgta ctaaattctt
    14941 cacttcctga tttccagaac gaatggcttc aaacaatcga ttttgttctt ctatcggata
    15001 tctaataagt gttttttcat gagcagcagg aacgatttcc tgataaaaaa taattgaact
    15061 tggaccagta tttacacgat aatacagggc ttcttttgcc cgatcaaccg attgcttgct
    15121 ttcattcagc gtttcgaacc ggttactgat gcctatactg atagttaaat tcaagtattc
    15181 ttttacacgt ttttgaatga gtcggcaata ctccatgact tttttgcttg cttctgcatc
    15241 atctttatcc attcgataaa tagtggcttg catttcttca ttcaaaacga tcggcagcat
    15301 tcgattttcc tttggcacaa tttccgtgat catgttgttg atcgctaaaa gtagcaaatc
    15361 acgctcccca ccgtgactat cttctaacag atcgatttga accaaagctg tataatagca
    15421 gtcattttga gaactataac caaattgctg caaccgctga tctagttctc gcctttctac
    15481 tcgatttcta aataaactaa gtacaaatag cgtttccagc tgtggctttt gggtaactaa
    15541 gtgtgcactt aacgcttctt tttctcctat gatccgactg actgattgag cgaccaaatc
    15601 tagttctttc ccactgaatc cttttgattt aagattcaga cgttcctgta tttgagaaat
    15661 cggacgggca aatctgtccg aaaataagta ggaaaaaaga ccaatgagtc ctaccagtgt
    15721 taaagacact gcaactagcc cgattctcag attgcggatc attgcgccaa ttgcactaga
    15781 gtcaacttct aatctgtaaa tccaattatt ataatctgat ttcagtacta tatacgtttt
    15841 atctttttct cttatcactt tcagctgatt gtaatctaga tccacgtccg ttaatacagt
    15901 tggttgctct ttatttttta ctgtctgagt agtaaaaagg ttgccaactt cgttttcaat
    15961 agaaagtatg tcttctccac tttcaccaac aacttgttct attgtatgtt tctctatcgt
    16021 agcaattccc aatgcatatt tttctttttc aaacattggc aaagaaatca ccatttcgat
    16081 tcctttgttt ttcttttgcc aaaataaatt atttttgtta tttatgtact tctgttgata
    16141 cttttcaact tcctcttcgg tcagttgact caacgatcca ttgattactc cccatttacc
    16201 agccaaactg actaaatcat aattattatc atccataaca atcgtttcta taaaatttag
    16261 ttctttcctg atttcagaat aagtggagta atctgtatat gtcagcggat gcttgaatat
    16321 gtccgagaaa tttttggtcg aaccatacgt agaaaacgaa tattcaatcg ttctaatttt
    16381 ccattcaacg ttagttttaa cttgcctgag caaattcttt ttgtctgtta aataactcga
    16441 ttcgatcgat tcataggtat tctggtaaat gaataaacta aatcctatga caagtacggc
    16501 tcctaataaa aacatcggta aaaatatttt ataaaatact gtacttttct tcattttctt
    16561 cctctcctcc ttttaaaata aaaggctttc atttttctgt aaaattgata ctcatctaat
    16621 taaatgagca ttccccgctt tcaagaatag cataattaaa aataaaaatc caagtaattt
    16681 ttaacgtgtg caatcttttc atatcaaaga tctattgact tatcgtagtt atcgtaatat
    16741 gatgaatgcg ttaacaaaaa gtgaaaaagt aaggaaaatg atggaatggt aacgatcaaa
    16801 gatatcgcta aagcagctgg cgtttctcat acgacagttt ctcgtgcttt gaataacagc
    16861 agtttaataa aaaatgaaac aaaacaaaaa atacgacaac tagctaagga aatgaattat
    16921 tcgccaaact atagtgcaaa aggtttagtg aatcaaaaaa aatatctaat cggactattt
    16981 ttctcaagtt tgcataaagg aacttcatca aatttcctag cagattccat tgcaggcatc
    17041 cattcagtat tagacacaaa ttacagttta tctgttgaaa gtatcgatgt tgttgattta
    17101 acagaaatca acctgcaacg ctacgatgga ctgatcgtta tgagtcaaag tgatgatgat
    17161 cagcctttca tcgactatct caaagaaaaa gaatttcctt tcgttgttgt caatcgtcac
    17221 atcaatgatc cagcggttat caacgtcact gccgatgatg cggccggtgt tatgcaggca
    17281 gtagattacg gtattggatg cggacatacg aagatcgctt atattggcgg aaagaaaaat
    17341 tttcgttcga caaaagaacg ggaaaaaggg gtattgaaaa gtctaaaaaa agcgagcatc
    17401 cctgtcaatc tagcctattt tttaacagga gattacagct tagaaagcgg cctccaaaac
    17461 atggaatacc tattatcact ttctgacctg cctactctgg ttttttgcgg caacgacgac
    17521 atagcgattg gtgcattgag agctgtacat ttagctggcc tccgtgttcc ccagaacatt
    17581 tctctgatcg ggttcgatga ttctccagtc gtctcctatc tcaatccgcc gcttaccacc
    17641 gtacgtaagc ctttgaaaga aatgtgtcaa gaaggaacaa agcttttact agatttgatc
    17701 gaaggcagga cgatcgaaca atctaaaatt gagctctcca ccttgttgat ccttcgtgag
    17761 tcgatcaatt acttgtaaac tacaagtaat tttatataaa aatgttaacg tgtgcataac
    17821 acagaaagga agtttatatg aaaaaactga caaaagaatt agtgaaaaaa aacgaagcac
    17881 ctgtaaaagt tcttcagttt ggtgaaggca attttatgcg tggatttatt gattggcaga
    17941 ttcagcagct gaataaccaa caattgttta aaggtaatgt tgcaatcatt caacctttag
    18001 aacaaggtct tggaaatatg atgaaccagc aagataattt atatacggtc attttacaag
    18061 gactcagcaa tggcgaaatc gttgatactt ccgagattat caccgtagta gaacaaatga
    18121 tcaatcctta tgatgaatgg gatgcttatc tatctctagc agaaaatgac gacttggcct
    18181 atatcgtctc caatacaaca gaggcaggaa tccaattcgt ggagactgat aatttaacag
    18241 atactccccc acagagcttc ccgggcaaac tgacagcctt tttataccga cgtttcaaat
    18301 taaacaaagc tggctttacc atcattcctt gcgaactgat tgacagaaac ggcgaacgtc
    18361 taaaagaaat cattttacgc tacgcagaaa aatgggattt agaacctgct tttgttgagt
    18421 ggttagaaaa agaaaatgtt ttctgttgta gtttagttga tcgcatcgtc ccaggttatc
    18481 ctcgcgaaga tgcaggtgtt ttcaatcaac ggcataacta tgaagatcaa ttgatggtca
    18541 aagcagaacc attcatgctt tgggtgatcg aagggcctaa agaattggag aatcaactac
    18601 cattcaaaca ggctggcttg aatgtcatca tcacagatga tatgactcct tatcgtgaac
    18661 gtaaggtgca tttgcttaat ggaccgcata cagcgatggt ccctcttgct ttgttggcgg
    18721 aattggaaac tgtagaagaa gtaatgaaag atcctttatt ctccgcatat gttgatcagt
    18781 tattcaatct agaattgatt cctatgcttt ctttacctaa agatgaatta gccatttatg
    18841 ctgaccaaat caaagaacgt ttcttgaatc cttttgccca tcacaaatta gaagcgattt
    18901 cattaaatag tgtttcaaag ttcagcaccc gtctgcttcc agtgttcaag aagtatatcg
    18961 aagaacaaaa tcaggtacca ccgttaatca ctgtttcact agctgcgcta cttcttatgt
    19021 atcgaggcga tcaagtaaag ccacatgatg atgaaaagac gataagcgaa tttactgatg
    19081 cttggtctga taatggaaca gctattcctc gattattgca aaacgctgcg ctttggggag
    19141 aagatttgtc tcaaataccg aatgtgacag atacagttca agaaatagct gcaaagatcg
    19201 atcaaaaagg tgtccggtca gtattacaag aaatgaaagg aacgatggtc catgcttgaa
    19261 accctgcaac caacaatgaa attaaatcga cgagacagtg tggtcgtcgc attaacccct
    19321 attccaaaac aaacacaact gacgattgat cagcaaacga tcaccactct tgaagatatc
    19381 ccgcaaggtc ataagattgc attgggtgat ttgaaagctg gagacaacgt gatcaaatat
    19441 ggctatccaa tcggtcatgt gacgacagac gtaactgccg gtcaatggct gcacactcat
    19501 aatgtaaaaa ccaatctttc tggtgaattg gattatcgat atgaaaaaga tgtccatcca
    19561 agtcattacc tttttgagaa ccgaacattt caaggttact tgcgaaaaaa tggaaaagta
    19621 gggattcgta atgatttgtt tttagtacct accgttgggt gtgtgaatgg cattgctgaa
    19681 ctgatcgtca aacagttcaa ggaaaaacat ccagatctgg gacagtttga ccatattacg
    19741 attttaaagc atccttatgg ctgttcgcag cttggaaaag atcatcaaaa tactcgagaa
    19801 attttagcgg acgcagtaaa tcatcccaat gccggaggag ttttagtatt tggattaggt
    19861 tgtgagaaca atacagttcc tgaattcaaa aaaattttag gtgaatatga tgaagaacga
    19921 gtgaaatttc tagtggctca agatgtttac gatgagatcg aacaaggtgt ggctctatta
    19981 gaagagcttt taacagcggc ggaaaatgac cagcgcatat cagtcccgct ctctaagttg
    20041 aatgtcggtt tgaaatgcgg cggttctgat ggtctatcgg gaataactgc taatccttta
    20101 cttggtgcat tttctgacta cttgattgct caaggaggca gcacgatctt aacagaagtg
    20161 ccagaaatgt ttggcgcaga acaagtattg atggcacgag cggaaaatga agaagttttt
    20221 gactcaatcg ttgacttgat caatgacttc aaacagtatt tcttgtctta cggggaacca
    20281 gtttacgaaa acccatctcc tggtaataaa gcaggtggga tcactacatt agaagataag
    20341 tctttaggct gcacgcaaaa atcaggaagc tctcctgtcg ttgatgtgct acaatatggc
    20401 gaaaaaatca gaaaaccagg gcttagttta ttgcaagctc ccgggaatga tcttgtagct
    20461 gcctctgctc ttgcttcatc cgattgccag ttggtcttgt ttaccacagg aagagggact
    20521 ccgtttggct catatgtccc aacggtcaag gtatctacga atacaactct ttttgaacgc
    20581 aaaggtcatt ggatggattt taatgcaggc gtcttattag aacaaccaat ggaagtaatc
    20641 ttagaatcgt ttgttcaaaa aatcatcgct gtagctagtg gagaagaaac gaaaaatgaa
    20701 caaaatgacg ttcgagaaat tgccattttt aaaaacggag taacactttg attttcataa
    20761 aacagtataa aaagaaagaa ggaagattta tgtttttatc tgatgatttt ttattaaaag
    20821 acgattgggc gaaaaagctt taccattcct acgcaaaaaa catgcccatt attgattatc
    20881 actgtcactt agatccaaaa gaaatttacg aaaacaacaa tttcagcaat ctgacagaag
    20941 cttggttagg aggcgatcat tacaaatggc gcttgatgcg atcttgcggc gtgcctgaag
    21001 aaaaaatcac aggaaatgct tctgattttg aaaaattttt agcttggtgt caaaccgtac
    21061 caaaaattat cggaaatccg ctttacagtt ggtcacatct tgaattgaag cgtttcttcg
    21121 gtattgactt gttgataaat gaagaaaatg cagagaaaat ttggacacaa gcaaatgaaa
    21181 ttttggcagc tcctgatttt cgccgtcggg aaatcgcaaa aaaatcgaat gtagaagtga
    21241 tttgtacaac agatgatccc gcagacgact tgcactatca tcagttgctt gctcatgaag
    21301 aaccagattt gaaggttcta ccttcattcc gtccagataa agcactcaat attgaaaaag
    21361 aaggatttaa tgcatgggtc acactactgg aagaagcagc tgaccaaacg atcaccacct
    21421 atcaagaact gatagaagtc ttagggcagc ggatagaata cttccatcaa catggatgtc
    21481 gtgtttccga ccacgcttta gacatcttac gctataaaga agcggatgaa acagtattag
    21541 aagagatttt tcaaaaagca cgagctaaca aactattatc ttcagatgaa atcgatgctt
    21601 atcttacaga aacactgata catttgaccc acttctatca ttctcataat tggacgatgc
    21661 agctgcacat ccatgcttat cgtaactgta atacacaaat gttggaaaaa ttagggcccg
    21721 ataccggcta tgatggaatg aatgatcttt ctttgactat tcctctgcaa aaattattga
    21781 accgtgcaga agaaacggat cagttgccaa agacgatcct ttattcattg aatccgaatg
    21841 actatcctgc gattttagct ttgatgggct gtttccaaaa agaacagaat ggaaaactgc
    21901 agttaggttc tggatggtgg tacaacgata ctcgagctgg tatgcgcgat caattgacac
    21961 aatttgctga tggtagtgct ttggggaatt ttgtcggcat gctgacagat tcaagaagtt
    22021 tcctgtccta cactagacat gaatatttcc gtcgtgttct ttgtgaattt ttaggcgaaa
    22081 tggtcatgcg aggagaagca cctgaagatg aacaactttt aggaagtcta gttcaagcga
    22141 ttagttatac aaatgctaaa aattactttg gcttttttgc ctaattgatt aatagtaaca
    22201 gtaacgaatc aaaaacagga tagtgaaata acggaatccg tttatccacg ttttagagaa
    22261 gaagacggac caaatt
//
LOCUS       DADQCX010000044        21640 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.044, whole genome shotgun sequence.
ACCESSION   DADQCX010000044 DADQCX010000000
VERSION     DADQCX010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.044"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..369
                     /locus_tag="J8R83_001539"
                     /pseudo
     CDS             1..369
                     /locus_tag="J8R83_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(495..1574)
                     /locus_tag="J8R83_001540"
     CDS             complement(495..1574)
                     /locus_tag="J8R83_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9574670.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1677..2117)
                     /locus_tag="J8R83_001541"
     CDS             complement(1677..2117)
                     /locus_tag="J8R83_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9574671.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(2174..2584)
                     /locus_tag="J8R83_001542"
     CDS             complement(2174..2584)
                     /locus_tag="J8R83_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAZ9574672.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(2764..3198)
                     /locus_tag="J8R83_001543"
     CDS             complement(2764..3198)
                     /locus_tag="J8R83_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAZ9574673.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(3298..4146)
                     /locus_tag="J8R83_001544"
     CDS             complement(3298..4146)
                     /locus_tag="J8R83_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9574674.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            4535..6301
                     /locus_tag="J8R83_001545"
     CDS             4535..6301
                     /locus_tag="J8R83_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAZ9574675.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            6403..7662
                     /locus_tag="J8R83_001546"
     CDS             6403..7662
                     /locus_tag="J8R83_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9574676.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            7809..9110
                     /locus_tag="J8R83_001547"
     CDS             7809..9110
                     /locus_tag="J8R83_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574677.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            9113..9964
                     /locus_tag="J8R83_001548"
     CDS             9113..9964
                     /locus_tag="J8R83_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574678.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            9977..10792
                     /locus_tag="J8R83_001549"
     CDS             9977..10792
                     /locus_tag="J8R83_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAZ9574679.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            10943..12109
                     /locus_tag="J8R83_001550"
     CDS             10943..12109
                     /locus_tag="J8R83_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9574680.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            12339..12986
                     /locus_tag="J8R83_001551"
     CDS             12339..12986
                     /locus_tag="J8R83_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAZ9574681.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSETSTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            13070..14014
                     /locus_tag="J8R83_001552"
     CDS             13070..14014
                     /locus_tag="J8R83_001552"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAZ9574682.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            14149..15600
                     /locus_tag="J8R83_001553"
     CDS             14149..15600
                     /locus_tag="J8R83_001553"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAZ9574683.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            15621..16457
                     /locus_tag="J8R83_001554"
     CDS             15621..16457
                     /locus_tag="J8R83_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAZ9574684.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            16457..17116
                     /locus_tag="J8R83_001555"
     CDS             16457..17116
                     /locus_tag="J8R83_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9574685.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            17242..17931
                     /locus_tag="J8R83_001556"
     CDS             17242..17931
                     /locus_tag="J8R83_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574686.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            17937..18893
                     /locus_tag="J8R83_001557"
     CDS             17937..18893
                     /locus_tag="J8R83_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAZ9574687.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            18937..19449
                     /locus_tag="J8R83_001558"
     CDS             18937..19449
                     /locus_tag="J8R83_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574688.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(19705..20253)
                     /locus_tag="J8R83_001559"
     CDS             complement(19705..20253)
                     /locus_tag="J8R83_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9574689.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(20342..21523)
                     /locus_tag="J8R83_001560"
     CDS             complement(20342..21523)
                     /locus_tag="J8R83_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAZ9574690.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
BASE COUNT         7246 a         3890 c         4167 g         6337 t
ORIGIN      
        1 tccagaagaa aaaccagatg tgactccaga accagatacg gacgcaagag accaaggaat
       61 accagaaaaa ataaacaaaa aaacaattca agaggatgga aaaaaagaga gtaaaaaatc
      121 aaatctagca attctaaaaa taaatgaaga gcagctgaat aaaaaatcac gaatatttga
      181 tagcgcccaa tcagctgaaa ccttaaaaag tagcaaggat acaacctttg ctgtcctgaa
      241 acgaaaaata aacagctacc aaaatccgga gagtcacaaa acaaagttat actgtggagc
      301 ggaatcattc tattaagtat agcaacaatg ctttctgcaa aaagatttaa acaaaacaga
      361 tctctctaac atttgaataa tgtctgtgaa cgcatttttc aaataaaaag aaatatccag
      421 aaaatgaccc caaaatacca gattgaaatc tgatatttgg ggtcgttcat actttatctt
      481 tcttcatatt tattttaagg gatatctgtt tcttttggaa gatggttcgg gatctttttc
      541 actttcaata catctaaaaa gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg
      601 ccaaagaacc gttcgctaac aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt
      661 ttgctggaca tcaacttcgg attcagcaca taagactcaa ttagatggac aatcaaaatc
      721 gtaatcagga tataaacaac atctcggatg cctccttggg aataagctat gaaagataga
      781 ggaatacaag aaatgataac acctgctact gggatcagac ttaaaatgaa aatcatgatc
      841 gctaaactca gcagctgatg aaagccaaat acagccaagg cgattgtagt gagcaacgta
      901 tttaaaagag cgacaacaaa ttgagcttct aataccaaac caaatgtatt gacaaactta
      961 tcggcaaaat agtaaatatc ttgaaagaac caagaaaatt cactttttaa aaacaatctt
     1021 gagaatacaa ttgttttttt cttttcaatc ataaaaaaga aacttaagat gaatgacata
     1081 gcaaacgcca ctgccatttt tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca
     1141 ttttgaagct gttcaaaaaa atcgtttcgc tcaatataag tatggatata ttgtaaaaca
     1201 ggatctgcat cttttggctg atgctcgtaa aaattaataa cggactggat catgtcaaat
     1261 gtttgatgaa taagcatcgg gatatacttt gtgaatgcca gatagataag gtaaacgatc
     1321 agtgtataaa tcatgatagc taaaacacct gtagggattc ggacaaatcg ctgaatgatt
     1381 tgaacaagat gaatcatcaa ataagtaaag ataaatgtga gcaaaatggt tgtaatcata
     1441 cttctaacta agaaaagaac aaaaacgaca aataataaaa cagtgagacg gcgtattttt
     1501 tcattcgcca aaaaacgctg ataaacggtc aaatcgacaa cctccaaata acaaaaaata
     1561 aacacgttat tcattatatg atggaatatg aaaataagaa agagcaaaaa gaaaaaccgc
     1621 taaatgacgt tatcttatga gttggttttc ctcataaaat cgttcatcta gcagtttcag
     1681 ccctttttct ggtcttgatg aaaattatct agcatttttc gggtcagatg ttgcagtgta
     1741 tccaattctt cctgttcaag tggaagataa gacttgatct tttgtggaat accttctgct
     1801 tgtttttgca acgcagcacc ttgagcagtc agcgtaacat ttacgattct ttcatcaccc
     1861 gtttcacgct gacgattaat ataatttttt tctgctaact tttttagtaa gggagtcagc
     1921 gtaccagaat ccagacacaa atcatttcct agctctttca ctgaagtctt tttcttttcc
     1981 cataaaacta acatcacaag atactgggta taggtaagat tcagcggctt gaggagggga
     2041 gtgtagtgtc taatgatttc tttagaggcg gcatataaag gaaaacatac ttgattaact
     2101 aaatatagat cttccatttt tccacctccg ctgttttact atagtgtatc atagcggatt
     2161 tacacaaaaa agtctattca ctaactgctt tcagagtaac ttctatattt ccagctgtag
     2221 cttttgaata cggacacact ttatgcgctg cctctaataa ttcttgcgtt tcttccagag
     2281 aaagaccttc gatagatcct tcaatctcta cacctaagac aaagctcgtt tcactttctg
     2341 aataaaggga aacttgtgca ctgacagtag aagccccaga gatatttttt tgctgtttga
     2401 tcaattctaa tgcactgtta aaacatgcac tgaaaccagc tgcaaacaat tgttcagggt
     2461 tggttgcatt ttcgacgcgt ttaccaggag ctgcaatatt caattcgaat gtacgatcgg
     2521 gattatgcac ttctccagag cgtccgcctg tgttgatcat tttcgtagaa tacatttttt
     2581 tcataaaatt accaccttta attatatttt atacaattga attttacaca atataattgt
     2641 ggaaagcaaa gaaatggatt ggcataagat aaataagaga aagcacatga aacagacgcg
     2701 ctttctcgaa tagcaaacat atacaaaaaa tatcagagac aaaaaataat ctcatcataa
     2761 acattacata tatttctcaa aaagttgttt tctttcttca aaaattactt cacgatggac
     2821 ctgatgaagc atccataaat aaccaaaagg atctctgaac attgagttag tcacaccaaa
     2881 gtccatcatt tctgtcattt cttgaatctc tacacagcca tttcgtaatg ctttattatg
     2941 tgtgtcctcg atatcagaga cgatgatatt gaaccagatc gtatttggat gttcagcagt
     3001 aggagcagtc aaaccaagag acgtgttttc atccagcata tggaatctcg taccatacaa
     3061 ggtaaaaatg acttcattat tgcctctagg gtaatctgtt gcctcaatca gttgtatttc
     3121 atcaaagatt gtttgataca gttctagtgc tttcaaacta tcatttaata caaaatcgat
     3181 ttccgttcct ttatgcataa agatctcctc tccttttcag tcgaacagtt actagattct
     3241 tttattatac cagctaaaga aaacgcattc aaaaaaatag cggatttact taccaactca
     3301 ttcgattgga tgataagtaa atccgcgtcc cattacttct gctacgctgc tgacaatgac
     3361 aaaggcactt ggatcgattt cttctatcaa tggtttcatt cgggaaaatt catgatcagt
     3421 cacaacgatc aataaaacct cttttgactt tcgattatac ccgccttttg cctctagcag
     3481 ggtaaggcca cgtccaatct cagcacttaa gcgaaggcgg atgtcttcca aataatgttc
     3541 actcatgacc ataacagatt tctttcgatt gatacctgtt tcgatataag tcatgacaat
     3601 tgaagtgatt gcaatagata aaatagcata aagaaactct tctattccaa aaataaacag
     3661 attaagagaa acaacgaatg cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa
     3721 atatttttta aaaatgaggg gagggatcgt cgtaccgccg ctagaagagt tgtttttata
     3781 taaaatcgca actcctaaag caaaaatcgc acttccaaaa atgacagaca acaaccgatc
     3841 tgaagtaatc attgtttctg gaactattgc aatgattaaa ggaaaaacca agcttccgaa
     3901 aagtacttta aaaaagggtt ttttacctaa aaatagaaga gctagtacca acataacgat
     3961 attcaacact aaaataacta tagctcggtc aaagcctaaa gcagcttcca gtaatattcc
     4021 tagaccgctg acacctccag cagcaatatg atgaggccct aaaaacatat tgatagcgac
     4081 tcctaatatg aagagggcaa aaataatctt aatgtatgtc catataaatt gtctcgtttc
     4141 tttcatttat tcacttcctt aattcattaa taatactctt atcttattat aacttacttt
     4201 tcaccttaag ttaactttaa ttaataaaaa aattaggcta gtctaaatta ttatgtttca
     4261 ttcttctaga atatacttct acgccaaaaa ctgttaaaaa acttttactt tagaaaattg
     4321 gagaaattga tcgcttaaga taaattcagg acactaaata gtacaggaag tagactaaaa
     4381 cttttaaaag ttttaagtct atctatttgg caagtttaaa aaataaaaat tcggtatcaa
     4441 aaaactgtta ccgataacat ttttgaaagc gttgtctttt gcttctctat cacttatagt
     4501 gatgacgtca tattaaaaca caaggaggaa atcaatggat acagctgcaa tttatcatcg
     4561 accggaaagt gaatatgcat ttctatatac gaatacaaga tttcgtattc ggcttcgtac
     4621 taggaaaaat gatatcaaaa aagtatatgt gctatgtgga gatccatata ccataacaac
     4681 tgaaaaatgg tatcaaaaac aacgaccaat gaaaaaatgt ctaagtacca atgttcatga
     4741 ttattgggaa attgaagtga cgagcgaaac aagtcgctta cagtatgcgt tccatgttgt
     4801 tggggaagat aacacggact gtttttacgg tgatcaagga atttttcctt atcgagaaaa
     4861 tgtgattact gaaccaaatt tttattttcg aataccttat tttcatcaaa tcgatcgatt
     4921 cactattcca gaatgggtaa aagaaacagt atggtatcaa atttttcccg aaagatttgc
     4981 aaacggggac aaagcaaatg accccgaaca cactttacct tggggaagta aagatccaga
     5041 ccgagaagac tttttcgggg gagatttgca aggtgtgatg gatcatttgg attacttgac
     5101 ggaccttggc atcaatggca tctatttttg tcccatattt aaagccacat ccaatcataa
     5161 atacgatacg attgattatt atgaggtgga tcccgctttt ggcgataaaa aacttttaaa
     5221 aaacttgatt gatgaagcac ataaaagagg gatacgtatc atgttcgatg ctgtattcaa
     5281 tcatatgggt gtccattcac cacagtggca agacgttctc aaaaacggag aaaaatcgat
     5341 ctataaagac tggttccaca tccgtttttt cccagtagat tcttatcaga tgactgactt
     5401 accagaaact gctgaaaata tcccatatga tacttttgct tttactccat tcatgccgaa
     5461 actaaataca gcaaatccag aagtgcaaaa atatttgctg gatatcgcaa cttattggat
     5521 aaaagaattc gatattgatg gatggcgtct tgatgttgct aatgaagtcg atcatcattt
     5581 ttggaaaaaa ttcagagaag cagttacaga aatcaaacca gacatctata tccttggaga
     5641 gatttggcat tcctctcaag cttggctgca aggggatgaa ttccatgcag tgatgaatta
     5701 tgcatttaca gattcgatta aagattattt tgcaaaaaag aaaatcacag cttcacaaat
     5761 ggtcagtgga atgaatcatc agcaaatgct ttacagagat caggtgaacg aaggaacatt
     5821 caacttatta gattctcatg atactgccag gatcttgacc ctttgccaag gtaacaaaga
     5881 attgatgaag tctgtgatgg cctttatgtt tcttcaaaaa gggtctcctt gtatctatta
     5941 cgggacagaa atagggatga ctggtgaaga tgacccggat tgccgcaaat gtatgatatg
     6001 ggagaaggag gaacaagatc tagagctatt cggttttata aaagaacttg tttctctaag
     6061 gaaacagttg tctaagatta tttctgaagg ttctactcag tggctaatag taaatgatcg
     6121 tgaagataag ctctatttca cacggaaact agagggacag atcatctatg tttactttaa
     6181 tcagtcaaaa gaaccttggg tagtagaaca ggaaaatgag gtgattctta gtcaaaattg
     6241 tcagttgtta gaagacggga aagcagagat acgacaatac ggatttttga tcatgtgttg
     6301 aaaactgtta ccggtaacaa caagaaagcg tttgcaaatg aagatttgtg cccattataa
     6361 taagggtgta acagcacgtt gaatacaaag gaggaaatga agatgaaaaa aagaagtgtg
     6421 aaacagttgg gtttagggtt aatctcttta ggaatcttag gcggattagc ggcttgtggc
     6481 aatggtaact cttcagcaga aggggaagcc gatgaaggaa aaacgttaac agtttccgtt
     6541 gattctggat ataaagatta tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat
     6601 gtgaaaatca agctagtaga aaaggacatg ttcgatcagt tggaatcatt agcgttagat
     6661 gggcctgctg gaaagggacc tgacgttatg atggcagcat atgaccggat cggtgcgtta
     6721 ggacagcaag gacatctggc ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca
     6781 gacaaagccc aagtgactta tgatggaaaa atctacggag aacctgcagt aatcgagacc
     6841 cttgttttgt actataacaa agatttagtc gatacagcac catcaacgtt taaagatttg
     6901 gagaatctat ccaaagacag tcgttttgct tttgagtcag aagcaggaaa aaatacagga
     6961 tttttagcta aatggactga cttttattat tcctatggtt taattgcagg ttacggtggc
     7021 tatgtatttg gtgatgatgg cacaaatcct tcagatatcg gtttgaataa tgcaggtgct
     7081 gtagaaggaa tctcttatgc aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa
     7141 gacataaaaa gtgcaggaga cttcgccagc cagcaattca tgtccaataa aactgcagca
     7201 atcattgacg gtccatggca agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta
     7261 gccaaaattc ctactctaaa taatggacag ccttatcaac cgtttggcgg aggaaaagga
     7321 tgggtagtca gcaattatgc taaaaacaaa gacctctctc aaaaatggct tgattatgta
     7381 acgaatcagg aaaatcaaga aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa
     7441 caagctaggg aaacagcaaa ggctaaaaac gatgaattaa caacagctgt gattgaacaa
     7501 tatgaaacag ctcaagcgat gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca
     7561 gaaaacttga tgttcgatgc agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa
     7621 gcagtaaaaa caatcagtga agccatagaa caaaaatact gattaaaatg ataaccgtcc
     7681 atttttataa aaaatggaac aggtgcttca gataaaagtg gcaagagcga gatggaaaat
     7741 tatcttgctc ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg
     7801 gcattcagat gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt
     7861 cacttattcc agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt
     7921 tcgccatatt cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag
     7981 gattggttac tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag
     8041 gcactttgca attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag
     8101 acgcttatcg agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg
     8161 aagtcataca taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc
     8221 ttctcatgat ttttacgatc attttcccag tcctagttac attgttcact gcatttacta
     8281 attatgactt caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact
     8341 tttttagtat cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga
     8401 ccgtgatttg gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg
     8461 ttgttgctca ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac
     8521 catgggcggt cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg
     8581 taggtgccat caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca
     8641 gtgcaatctc ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg
     8701 gctggttagg atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag
     8761 aagacttata tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca
     8821 tcacgcttcc tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga
     8881 atttcaataa tttctccatg atctatctgt ttaacaatgg cggtcccgga agcgtaggcg
     8941 gaggagctgg ttctactgat attcttattt cctggatcta taaacttacg actggaactt
     9001 ctccgcagta ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg
     9061 tgtcattgct ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa
     9121 atttcattcg agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct
     9181 tttaatactg tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa
     9241 gtcaggaaat attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt
     9301 tactcggcta ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc
     9361 tgtcctaaca atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg
     9421 ctatcgtttt atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc
     9481 gactatggca gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa
     9541 gtactggttc ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat
     9601 gaaaggatac tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc
     9661 agggcatttc aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt
     9721 tcaagcatta tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct
     9781 tcgaacacct gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac
     9841 aaaccaaaga gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct
     9901 attattcttc tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg
     9961 ataggagcag agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc
    10021 aactcaagtg tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt
    10081 atttttagtt tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc
    10141 gattccatta gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa
    10201 attttctgaa cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt
    10261 gacccctgaa attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac
    10321 ttttattgat tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg
    10381 ccgctatacg atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga
    10441 tttccaacga tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc
    10501 ttatagttta agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc
    10561 ttcctttttc ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga
    10621 gagtgcaaat ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg
    10681 gtttatccac tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct
    10741 gcttttatgg gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta
    10801 agcgatttat gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt
    10861 tctgaaaaaa ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt
    10921 agttttttta aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg
    10981 ttctttctcg ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga
    11041 tacggacact cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat
    11101 tacaagtaac gcttctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga
    11161 gggaagtatc caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg
    11221 aaaagattat ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga
    11281 agatatccat gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac
    11341 tttgacttat tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat
    11401 caataaagtc catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga
    11461 tatcggttgt ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc
    11521 aactgggatc acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga
    11581 acatttagaa gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac
    11641 gtttgatcat atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg
    11701 ttatttcaaa gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat
    11761 cagccgacaa caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg
    11821 ttatgtccct ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat
    11881 tgatttggaa agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt
    11941 tcatcaagtc caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga
    12001 tctatattta caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata
    12061 tttgcttgtt caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa
    12121 gtactgttta aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt
    12181 ttttgtctaa cttctaggat tgtctctaaa gcttagtttc tttttcttta tattttcata
    12241 ataaaagttt ggttctttaa tttttaaaca tgacagaaaa ttttttcttc gttatacttg
    12301 taatagaata ctattttata acaaagggga tcgaatcaat gaaaaaaact gttatttata
    12361 ctagtttatt tgcagctttg tttttagctg cttgtcaatc aaataccaat caaggcacat
    12421 ctgggaatac gtcttccagt agcgaacagc gctcttcaca ggtatcggac tcctcaacaa
    12481 aagcaagcac atcttcgtct agccagacaa aaagttctag tgaaacaagt actcagtcag
    12541 atatcaaagt gtctgcagct cgtgcgatcg aattgttcca agataaatac ccagatactg
    12601 caattactag tttggaatta gatagtgatt ggggatctta cttctacaag atagaaggtg
    12661 tcgatgatca aaaagaatac gaagcaagaa ttgatgctca aaatgaaaaa atggagacag
    12721 agaatccaga aactctagat cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc
    12781 tggatgttga taaattgatc acgattgagg aagcagcaaa aatcgccgtc gacaaagtag
    12841 gaagcggtac ggcaacagat tgggatttgg ataaagattt aggtactact tattgggaag
    12901 tcaaagtaaa agacggcaat caaagtacat cagtcaagat caatagccaa acaggcgaag
    12961 tactgtcaac tgaacaagat gattaagaat ttcttcggaa aacaagagtt gatttttctt
    13021 ttagtcatga tacactagac aaaataactt gtttgaagga gcgatttact tgagtttaga
    13081 aacgaccttt gccaatcata tctttgccaa tcctttgatg aatgcatctg gtgtccactg
    13141 catgactacc caggaattag atgaactggc tcattcagaa gcaggagcat ttatcactaa
    13201 gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca cgctattttg atgttccttt
    13261 agggagtatc aattctatgg gacttccaaa cttaggtttt tcttattatc tagagtatgc
    13321 tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg ttattttttt ccattgccgg
    13381 gatgagtgtc caggaaaact tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg
    13441 gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga aaaccacaac tagcttacga
    13501 ttttgaggcc acttatgaaa cactgaaaga agtattcagc atcttttcta agccgctagg
    13561 aatcaaattg cctccttatt ttgattttgc tcattttgat cagatggctg atatcttgaa
    13621 tcagtttcca ttgacctatg tcaatgctat caacagtgtg ggcaatggtt tgtatatcga
    13681 tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg ttcggcggca ttggcggaga
    13741 gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga
    13801 aatccaaatc attggtacag gtgggattcg gacaggacaa gatgcatttg aacatctgct
    13861 atgtggcgca agcatgttac agattggtac cgagcttcat aaagaagggc cggaaatttt
    13921 ttctagaatc ataaaagaat taacgcagat tatgtcagaa aaaggatata cgtcaattga
    13981 cgaatttaaa ggcaaattac gcaccatttc atagcaaaga gacgaaggtc atgattgatc
    14041 ttcgtctttt tttataaaaa acactcgtct gttcattcct gtgcaagcgt actcattgta
    14101 tgttagacga acttgtggga aaataacaga ggcaaaaagg aggataatat gaatgatgca
    14161 acagaattag caaaagagct taaagaaaaa gaatttagtt ttcaagaact agttacggat
    14221 atacagaaaa aaataaagaa gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca
    14281 ttcgagagta attcccacga gctattgatt ccccagtcag aaaaagggcc attggctggt
    14341 atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg gatggctagc tacttcagga
    14401 tctcgtttat ttgaaacaca ccgagcttct catacatcta attatgtgcg gcaagcagaa
    14461 gcgataggtc tagttccttt tggacaaacc aatgcgccag agtttggttt caaaaatatt
    14521 acagacccag tcatctatgg cccagcaaga aacccttgga accttgaatg tacaccgggc
    14581 ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa tcgttccttt agctggtgct
    14641 agtgatggcg gtggttctat tagaataccc gcttcgtttt gcggattgat tgggctgaaa
    14701 ccttcgcgag ggacgatgcc agttggtcca tatgcttgga gaggatggca aggagctgct
    14761 attgatttcg gcttgacagt ttctatgaga gacacggagg ctttatttta tgggatgaga
    14821 agtatccatt ccggtgcgcc atatcaagta tcgccagttg agtggcaaac acatccaaga
    14881 aaaaaacggt tgaagatagc tttttgtgtt gattcaccga tccactcaca gattagtgaa
    14941 gaggcagtac ttgctgtaaa aaaagctgta gatttccttg gaaaagaagg gcatgatttg
    15001 acagagattc cttacccact agatggtcgt aaactgatca cgtcttatta tcagatgaat
    15061 ggcgcagaaa cagcagcaat gatccgctcg attgaaacag gcatccagcg agctgtcaga
    15121 aaagaagaac ttgaacccat ttcttggact ttgttccaat atggtcagaa gctctctgcc
    15181 gctacttaca tcgattctct gcatgtatgg gatgaagcag caattgtcat ggaaaaccta
    15241 catcaagaat acgatctatt cctttcacca acgactgcat ttaccgcccc taaaatcagc
    15301 gaagatttgc aaagtgatgc gataagagca cagatggaac acatcagtga ttgttctgaa
    15361 gtagaaggtt tagacgttgt ttcttccatg tttgaggaga gcttgaagat cacaccttat
    15421 acacagttgg ctaatctgac tggacaacca gcaatcagct tgcctactca tttgacaaaa
    15481 gaaaacatgc ctctaggaat ccaatttatg gctgccagag gaagagaaga tttgctattt
    15541 caaatcggct atctatttga agcaaatcat cagttccatt taccaaatcc atggaaatag
    15601 cagaaacaag gagaagaaga atgaagaaaa aaagattgtt tgctctaata actagtgcct
    15661 tttttatttt aagcgcttgc ggtacagctg ccgctaatca ggaagataac agctggagta
    15721 atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg cacactgttt cccgcatctt
    15781 attataatga tcaaaatgaa ttagttggtt atgatgtaga tttggcaaaa gaggtggcta
    15841 aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt ggatggacaa atcacttctg
    15901 tttcaaaaag agaatcagat tttgctgcga acgattttgg tatcacaaaa gaaagagaaa
    15961 aaaaattctc cctttcagag actttcaaat attcatttga cagtatgatc gtacgaaaaa
    16021 aagatgattc aggaatccac tcacttgaag atcttaaagg gaaaaaagca gctggcgaac
    16081 ccaatactag ctatatgcgt ttagcggaaa aacacggagc taaattagtc acatatgaca
    16141 atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg tcgaacagat gttattctaa
    16201 atgattatta tctgcagaaa atggccgtat ctgctttacc agatatccct gtaaaaatac
    16261 tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg
    16321 ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa agaagatggg acgacaaaga
    16381 aaatatctga aaaatatttt caaactgatg tttcagtcaa accgaaagaa acgatggctg
    16441 agtcggtgag tgagtgatgt actttcctct aattgatttt tccctcatgt ggacttcact
    16501 tcctttcgta ctgcaaggct tggtatacac attagggatt ggcttcgtgt cgtttctttt
    16561 aggaaatctg gtagggttgc ttttgacagt tttaggtctt ttggattggc tgcctctgaa
    16621 tgtatttatt cgtttttatt tatcgttctt tagaggcatt cccgcactag tcctgctgtt
    16681 tctgttatat tttgggttac cttatcaatt aagtgcctta acggcttcag tcatctgctt
    16741 tacgattacc agcagtgcat ttattggtga aatctatcga ggatcactag caggcgtttc
    16801 ttcaggtcag tgggacgctg gtttagcttc tggtttttct ttctttgggg tattgaaata
    16861 tatcgttttg ccgcaagctt ttcgaatctc agtaccggca ctcagtaacg tagctatgga
    16921 tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc
    16981 aaagatcata ggcggtcgga cattcgatta tttttctctc tatattttag ttgcactgat
    17041 ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag tatttagaaa aacgttctat
    17101 gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg ctggcaccat ttctattttt
    17161 tgtttcttgt atattctgcc tagtatttta aaaccatttc atgtaaaatg taaatcgaaa
    17221 atatgttcgg aggtagaaaa catgaagacc ccgctaacca tcgaaataga atcctcgtta
    17281 taccaatatt gcatcgagca aggcggcttg gttgtagaag aagtcacgat gcctgatgac
    17341 caaggaattg tagatacgct tagctgcttg acaaaatttg atggaagccg agaatggcga
    17401 tgctatgagc tgaaagtgac aaaagcagat tttcgctcta cagccaaact gtcatttgtt
    17461 ggacattata attattttgt tttaccaagt aaactatatg aagaagtaaa aactgaaatc
    17521 cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc
    17581 tctggtacat ttctgattgc gaaaaaagca gcaaagaaag agcttgctgt accggaagaa
    17641 gctttgacaa accgcttcat ggcttcttta ttcagggaag taagaaaagc aaagcaaatg
    17701 gagcgaggcg taaaatattt tccaacagat caattgtaca aagaattgaa aagacgttca
    17761 gaaaatcaag atccattttc taacgaacga tattatgaac ggtttttaga ggaaatagct
    17821 agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat
    17881 ttgaggcaac aacagcagat ccgtcggttg cctacagagc cattggagtg aaaaatatgt
    17941 actatcctta tttaagagga aaacaatttg acctattagc attaaaagaa gcactgtcgc
    18001 gaggattgct ctccaataaa atccaaccag tgatcgaacc agtacgtgat tccgctacgc
    18061 ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcc aatcgctgtg atccaaaatc
    18121 cccaagtagg acaattcaaa ttattcgatc agcatgtgca cagttggaca gtcaaagaaa
    18181 atagctctgt cgtccctgca cagatcttaa cgccagaaaa tctcagtgaa gtactggatt
    18241 cacctccagc gtttcttgtt ttcgatggac agcactaccc aaaagataca gaggtgtgga
    18301 aacagttggc aggagttgat tcgaaatttt tgataccaga tactagtcgc tttcgcatct
    18361 ggctgcccga aaacaaaatt gtgatccgtg actcttttca aacgagaaag catgttgaaa
    18421 gttatgcaga taaaacagat gactttttta gtgatgacta tctttttttc cacgcagacg
    18481 gatatattgg attttctgat ttcacgatcg aaggtagccg ttatttcgat aaagggttcc
    18541 ctagccgagc gcttgctatc catctaacgt atattgatgc ttacggcaat atacgcgtga
    18601 aacattttgt ctctgacagt aacgactctg ctaaagacca agcattgaag tttcttgaag
    18661 caggagataa aatgaaaaaa tggatcatgc gtcaccatca tcaactcttg attacttcag
    18721 gaatgattga attattggct ctttaccagc aacaaaaatt ccctggactg ggagtgttga
    18781 aaaagtggtc acttatgcat catttggaac ttattagtca cctgctagat catccaaaag
    18841 attggcttaa atattattca aaagttcagg aactatatga agtgatccaa tgattagata
    18901 atgtaaatga aaaaggaata gaaaagagga aactggatgt atattcggca aacaaggaaa
    18961 gaagaagtag aagaagtggt agaaatcatt aatgccgcag cggatttcat tgcttcgcaa
    19021 ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt
    19081 gaaagaaaag aaagctatgt attaatagtg gaagatcaaa ttgctggaac agctgcatta
    19141 gtctcaagcg tggatcccgt ttacacaaaa atagatggta gttggaaaga atcaactggt
    19201 ccttatttat cgattcatcg tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca
    19261 aaaccgttct tagaacattt gttgacgatt gcagccagca aaaatatcca agatatccgt
    19321 atcgatactt atccagctaa tgaaccgatg gaaaagacca tctattctgc tggattcact
    19381 tatcaaggga tgattgaatt tccttttgaa cacggcgaaa gaaaagcata tcaaataatc
    19441 atcaattgac tataaaatca tctgagcaaa gataaagaca ttaacactac tgaaaaaaac
    19501 aatcatatga tagccaagag gttgtaacag aagtggccag cttcaaaaaa caagaaagaa
    19561 tttccgaaaa tgcttctcaa atttttgtgg aattttagcg tattttacga aatagctgct
    19621 ttctgaaact cccttcatcg agaggtcgtg acatagcttt tgtcacgacc tctcggctta
    19681 tcctacgagt attattcgat acatttatat caataatcct ttttttattt tatctgcagc
    19741 ttcttggaac gctccatcgt ttgacacgac taaaagtgag gggatagctt tcaaacgttt
    19801 caactgtgct aaatcttcta cataaaccgc cagtctggct gaaatctgtt cagatgaatc
    19861 tccacgtttt ttcaggcgcg attgcaatgt ttctttagag atcgtaataa agataggacg
    19921 gactaccgtc ccgaaatact catataaatg ccaaaaacca tttgctgtca aaacggcgta
    19981 acaatttcct actgtcagtt tctttttaat ttctgcttta ctggaaccat atttatgttg
    20041 agcatattgg tcccactctg caaactcatt tcccttgatc atctgattga atgtattgtc
    20101 agaaacaaaa taataatcct cttgatcttt ttccccaggt cttggtgatc gattcgtgta
    20161 agtaatgatc ttttgttccg gctgaaaaat agcttctgcg agtgaagttt ttccagaacc
    20221 agaaggaccg ataaatacat agcaataatt cattgtcatt tctcctttga tgattgaaca
    20281 agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa gtaactttgc ttttttgtat
    20341 attataccag caagccagtc acaatagcac ttaaaaagct gactaaagtc gctgttagca
    20401 aaattttcaa tccgtgtttt gcgacaagat ttcctttttc ttcatttaat cccttcatcg
    20461 caccagaaat gatcccgata gaagagaagt tggcaaatga aacgaggaag acagatataa
    20521 ttgctgttgt acgctcagta aaatggaaat taccatttgc taattctgtc atagcaacaa
    20581 attcatttgt aaccagttta gtcgccatga tactaccggc atccactgct tctttccatg
    20641 ggattccgct gatgaaggca agaggggcaa agatgtaacc taggatctct tggaaagtga
    20701 tgccgaatat cccgtggaag atagcattga tcatggcaat caaagcaaca aaaccgataa
    20761 gcatagcagc aaccgtgatc gccacatgga aaccatcaag aatgtattct cccaacattt
    20821 ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc atcttctttt tcttctaata
    20881 catagggatt tacaattgaa gccagaatat aaccgccaaa taagttcaaa acaagggcag
    20941 tgatcacata tttagaatcg atcagtgcca tataagatcc gacgatcgac atagaaactg
    21001 tagacatagc cgatacactc atggtgaaca aacgtttctc agataggaag ggtaattcct
    21061 tttttatgga aataaaaact tccgattgtc ctaaaatagc agaagctact ccattataag
    21121 attccaattt gcccatcccg ttgattttac ttaatcctag accaacagct ttcataaata
    21181 atggaagaat cttgatatag cgtagaatac cgataatagc agaaataaat acaattggca
    21241 tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc tacaccggca aaaacaaagt
    21301 caacaccttg cccagcaaaa gcaagaagat gatcaaacat ttttgccaat acagaaacaa
    21361 ccgctgtacc aaaagttgta cgtaataata cgaaaccaag aacaagctgt aaaacgaaca
    21421 tcacaattag tggtttcaat ttgattgctt ttttgttact gctgatcaaa aaagcaagcc
    21481 ctaatgtgac aaataaacca ataataccta ataaataact caaataatca ctcctattcc
    21541 aaattccgtt ttattttacc tgttttgcaa ataaaatact aatctttagt gaaattttca
    21601 ttactttttt agagtgaaac gcattcattt tccattagaa
//
LOCUS       DADQCX010000045        21548 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.045, whole genome shotgun sequence.
ACCESSION   DADQCX010000045 DADQCX010000000
VERSION     DADQCX010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.045"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(61..1440)
                     /gene="brnQ"
                     /locus_tag="J8R83_001561"
     CDS             complement(61..1440)
                     /gene="brnQ"
                     /locus_tag="J8R83_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAZ9574691.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            2146..3117
                     /locus_tag="J8R83_001562"
     CDS             2146..3117
                     /locus_tag="J8R83_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAZ9574692.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            3141..5333
                     /locus_tag="J8R83_001563"
     CDS             3141..5333
                     /locus_tag="J8R83_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAZ9574693.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEVQEE"
     gene            5350..5826
                     /gene="ybeY"
                     /locus_tag="J8R83_001564"
     CDS             5350..5826
                     /gene="ybeY"
                     /locus_tag="J8R83_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAZ9574694.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            5804..6205
                     /locus_tag="J8R83_001565"
     CDS             5804..6205
                     /locus_tag="J8R83_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAZ9574695.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            6220..7119
                     /locus_tag="J8R83_001566"
     CDS             6220..7119
                     /locus_tag="J8R83_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAZ9574696.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            7262..8074
                     /gene="recO"
                     /locus_tag="J8R83_001567"
     CDS             7262..8074
                     /gene="recO"
                     /locus_tag="J8R83_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAZ9574697.1"
                     /translation="MSQLVESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            8458..9375
                     /gene="glyQ"
                     /locus_tag="J8R83_001568"
     CDS             8458..9375
                     /gene="glyQ"
                     /locus_tag="J8R83_001568"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAZ9574698.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            9377..11452
                     /locus_tag="J8R83_001569"
     CDS             9377..11452
                     /locus_tag="J8R83_001569"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAZ9574699.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRVSRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQITAMALSL
                     ASLDQIITK"
     gene            11836..12615
                     /locus_tag="J8R83_001570"
     CDS             11836..12615
                     /locus_tag="J8R83_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574700.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            12656..13600
                     /locus_tag="J8R83_001571"
     CDS             12656..13600
                     /locus_tag="J8R83_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9574701.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            13616..14395
                     /locus_tag="J8R83_001572"
     CDS             13616..14395
                     /locus_tag="J8R83_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAZ9574702.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            14408..15106
                     /locus_tag="J8R83_001573"
     CDS             14408..15106
                     /locus_tag="J8R83_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAZ9574703.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            15134..15898
                     /locus_tag="J8R83_001574"
     CDS             15134..15898
                     /locus_tag="J8R83_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAZ9574704.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYKQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEIKKKKFGLF"
     gene            15911..17728
                     /locus_tag="J8R83_001575"
     CDS             15911..17728
                     /locus_tag="J8R83_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9574705.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISTGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASDVSSILILLFINRQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIQVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAKGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNK"
     gene            17742..18965
                     /locus_tag="J8R83_001576"
     CDS             17742..18965
                     /locus_tag="J8R83_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HAZ9574706.1"
                     /translation="MNKLEKRQIPFSPPDITDLEIKNVVEVLKSGWITTGPKTKKLEK
                     KITKWLGTSKVVCLNSQTAAAETGLRLLGIGENDEVIVPAYTYSASAPVVCHIGANLV
                     LIDCQQDSLEMDYDALEAAITEKTKVIIPVDLGGIPCDYDRIFEIVEKKRNLFQPSNE
                     IQKAYGRIIVMADSAHAFGANWHDQMVGNVADLTTFSFHAVKNFTTAEGGALVWKEHD
                     KLDNEAMYHQCQLLSLHGQSKDALTKTQLGAWEYDIVGPWYKCNMTDVTASIGLAQFE
                     RYPNILKRRKNIIKRYDEAFQQLGIEVLMHYTDDYSSSGHLYITRVPNISSEQRNEII
                     IKMAEQGIACNVHYKPLPMFTAYKNMGFDINNYPNAYAHFVNEITLPLHTKLTDEEVE
                     YVINNYSKIVKDLVG"
     gene            18979..19713
                     /locus_tag="J8R83_001577"
     CDS             18979..19713
                     /locus_tag="J8R83_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006443581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAZ9574707.1"
                     /translation="MRKWEDLPKEMQNDEIRYYYDILSKKKFSLVVKRVFDILVSATL
                     LLTLSWLFFILAIVIKIDSPGPVFYRQERITRYGKKFKIYKFRTMVINADKDGTLVTV
                     KNDDRITRVGKVIRKYRLDEISQLINVLVGDMSFVGTRPEVGKYVKSYSPLMLATLLL
                     PAGITSETSILYKDEDKLLHDKNNIDKTYIEKILPSKMYYNLKSISEFSCMNDLKIMC
                     KTIFVIFGKEYHADLEGEREFINQIK"
     gene            19730..20341
                     /locus_tag="J8R83_001578"
     CDS             19730..20341
                     /locus_tag="J8R83_001578"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574708.1"
                     /translation="MVIEEIKSSDKELINSIVDIHMRTFTNFFLTFMGKKFLELMYRS
                     YTEYNDSGILVAIQNDKPIGFLAYSGDMSGLYKYMIKKRIIPFGFYSCVAFIKKPNIL
                     MRLFRAFLKPSETKRDENYVELASIGVNPKEKSIGVGSMLIDNLKSRIDFSKYEYIAL
                     ETDALNNDVVNNFYKKNEFILERKYSTNEGRIMNEYRFYMEKN"
     gene            20344..21489
                     /locus_tag="J8R83_001579"
     CDS             20344..21489
                     /locus_tag="J8R83_001579"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9574709.1"
                     /translation="MKLLYILNVANKVNNFSKASMMAAKQTGLEFYIAGNWKYKSDEE
                     RKADEVKYGIKIYQVDFYRNPLNLKNIKAYHQIVEIIKNEKIDIIHCNTPIGGVVGRI
                     AGLKCKVKKVIYQAHGFHFYSGAPKINWFIYYPMERWLAHYTDVLITINHEDYTLAQK
                     LRLRKGGKAYYIPGVGIDTNRFMSSTSIRNFRESICKELNIPDTAKIILSVGELNENK
                     NHLSVIHALQKIPLHTDIYYIIAGVGEMRETLQNIANELGLHQRVFLLGYRSDIPKLL
                     AAANIYILPSLREGLNASLMEAMASGLPCIVGNIRGNVDLIEDGKGGFLINPKDEEEI
                     AGAINRLADNKLLCESMGAHNLDKIKDFDLSVVINQINNVYHEIVSK"
BASE COUNT         7451 a         3725 c         4447 g         5925 t
ORIGIN      
        1 tttcttctag ctgttttttt cctgtttaat atctcttatg ttaaattgtg tttgatttgg
       61 ttattcttct ggtaactcac ttgcttcttg tttatatcct gatacgcgat atacataata
      121 aaagagcaag ctgccagcgt aaccaagcaa tgttgggacg acccagccaa gacctaatgc
      181 agcaaaagga acataatgat gataaaatcc tagtaagctt gctacgacag tttgctgact
      241 cactaatgca ggcgaatttg ccaacatatc caatacggct ggaacggcag aaaagaacat
      301 cgttacttga tagacaaatg gactcttttg gaagaatttt gctgttaagg aaagtaagat
      361 taacgcaagt gacaatggat acaaaagcat caatactggt aaagaccatt ggatgatatt
      421 atccaatccg gcattcgcaa cgacaaaaga gacaaaagtc gttaaccgca gccatgtcat
      481 ataactgact ttagggaaca gtttatggaa atcttgtgca aaagaaacaa cgagtcccat
      541 agcagtagtg aagacaccta atgtgaccat tacccctaag aagctagcac cgaagttacc
      601 taaataaaaa ttagtgatct gagaaagtgc agttccgcca ttttctgata aagacatctt
      661 attcaaactc atcgcaccga gaaggaccag accaaaataa atcatgactt ctaacgcaac
      721 gctcaggcta ccagcttttg ctgttaattc tgtgactttt ttatctttaa aaccaagatc
      781 acgaactgca tggacaaaag tgacacttaa agcaagtaaa gctactgcat caaccgtgtt
      841 gtatccttct aaaacgccat ttgtcaaagc gttcgtctga taagaatctg cagcagattg
      901 gtttagattc cccatgggtt ggaataaaga aacgacaaaa atgatagcta ataatgcaag
      961 aaacaaggag tttaaatact ttccgacata tttgaccaaa cgtgttggat gtacagtaag
     1021 gaaataagca agtaaaaaga aaagagcaga gaataaaaac atacctaatg aatcatattt
     1081 ttcaggcaaa aagggtttag cagccatttc aaaagcagtt gctgctgtcc gcggtgtacc
     1141 aaagaatggt ccgatcgtta aatgaacaag gatcaagaac aaggcagcat accattttcc
     1201 gacaggttta gctaagtcat acagaccatc actttttgtc actactacag ctaagatagc
     1261 taataatggg aaaagagcgc ctgagatggc aaatcctaca ccagcgctga tccagtttga
     1321 tccagccatt tgacctaagt gtacaggaaa gatcagatta cctgacccga agaacatccc
     1381 gaagataagt gaactgacca tcaataattg cttccatgaa taagtttttg tttcttccat
     1441 aaatttttcc tccaataatt atcattttga gtaacaaaat aaacgttgca gaaactagaa
     1501 ataccactaa tatcagattc catgaaaacc accaccttaa aatataaaaa aagccctttt
     1561 ccacttggga aaagggctct agattctaga acggtaccac cttttttcgc ttaaaaaagc
     1621 ttcttcattc acggacgctt ttcgataaag ttatccgcta gcctgataat ggaggcagcc
     1681 acaatgatct acgttttcga cattgactcg gaaatgatgt tcgtctattc gatttattgt
     1741 catttctcac ttacatgact cactgggaat aaatcactga atagcctact gttttcctcg
     1801 acgctttgct gtatatttat ttgttgacgt tataatacac ctgttttttt tgaaatgcaa
     1861 gaatatttca aatattttgt tttctttttt tgaaacaaga aaaataccca gagaatactt
     1921 gctaagttag acggaatact tgtcctctat cttatgcata gcttacatga tcagcttttt
     1981 ttattcaaac gagaccttta gagaatggaa gcggctagtt ttttaacgtt tcttggtact
     2041 tatggttaag caactctttt agaacctttt cttatttgct atatagtttc ttctgagtat
     2101 ggtaaaatag gaaagaatta atcgaaaaaa aggggatgtc tatttttgac ggaagagtct
     2161 agttctttag agattagatt gacggctgct gatgatgtca gcatgctttt aggtgcacac
     2221 gacaagcata taaaactgat tgaggaaaca acggaaacaa ccatccatac acgtggagaa
     2281 atcattcaga tcattggtga gcaatcccag atttccttgg ctgcctcagt cattcggaca
     2341 ttacaggaat tgatcaaacg aggaatccac gtaagtacgc ccgatgttgt gacggcattg
     2401 aaaatggggc aaaaaggtac attagattat tttgttgaga tgtatgagga agagatcgtc
     2461 aaagaccgta atggaaaacc tatacgggta aaaaacagcg gccaaaagaa atatgtcgaa
     2521 tcggtagcca aacatgatat cgtatttggc gtaggaccag ccgggacagg aaaaactttt
     2581 cttgcagtag tattagcaat cgctgccttg aaaaaaggtg aagtgcaaaa aatcattttg
     2641 acgcggcctg ctgtggaagc aggtgaaaat ctaggctttc ttcccgggga tctaaaagaa
     2701 aaagtggatc cttatctgcg gcctgtttat gatgctttat accaaatttt tggattggat
     2761 catacgaacc gattgatgga acgaggcgta atcgaaatcg cacctttagc ttacatgcgg
     2821 gggcgaacat tggatgatgc attcgttatc ttggacgaag cacaaaacac gacagtcgct
     2881 cagatgaaaa tgttcttgac ccgtctcggt tatcaatcaa aaatgattgt caatggggat
     2941 acaagtcaga tagacttgcc tcgagggacg acaagtggtc ttgttcatgc agaacgaaca
     3001 ttaaagcaaa tcaagaaaat cgattttgtt aattttgaag caagtgacgt tgttcggcac
     3061 cctgtagttg ccgaaatcat caaagcttat gaaaaggcag atctccatca agaataagct
     3121 ttgcttagga ggataagcac atgttgaata aaacactgca gaaactacaa gaaaaacttg
     3181 gaaaggcagc attgcctttc ctgctgttct tgttttttat cattatctgc ggcgttacat
     3241 ttagtagtgt caaacaaaag gccaatgatt tcagagaagg ccaagtagca gaagaaagta
     3301 tccgtgcgaa caaaacgatc gagaacacgg aagaaaccga acaaaaaaga aaactggcag
     3361 cagaagcagt cactccagaa tacacttacc aaaaagatct tgcagatgac cagaacaatc
     3421 ggatcaagca actatttgaa ttgatcgata agacgaatga tgccatcaac aaatcttatg
     3481 acgaaaagat tgataaggca aaggaagatg aaaatatccc aaagcctact acagaagagc
     3541 ggatcgccgc gctgaagaaa aattttgaaa atgtgaatgc agaaaatgtt gtgttttatc
     3601 aaaaactacc gaacaatttt tattcgacga tatttgaaat gactgaaact gagattcata
     3661 ctgtgaggga tgagagtctg aagctcattg acgaacagat gagcaaacaa gttcgtgaaa
     3721 gtgaattgga agcttttaaa caagaagcag aagagcaaat ccaatatttg aatgtcacac
     3781 cagcacaaca acaaatgatt cgctacttag tggatcaagg tatcgtagtg aatgacgtat
     3841 tgaatgagaa aaagacagaa gaattgaaac aatccgcacg agaagctgta caaccagtga
     3901 tgatcttcca aggagaaatc attgttcgtg aaggtaatca aatcgatgct tcagctatga
     3961 aaaaattgga attactagga ctgactaatc aaacaacttc gatttttccg ctaattgcca
     4021 tggttttagc tgttttgctt caaatcggcg tactgattta taattcactt caattccaaa
     4081 atgcaggaga aagaacaaaa tacgtgcttt tctatgtgac agctatgtca gtcagcatag
     4141 tgctgatgaa atttttccaa ttattccaaa cggaacaagc tacttatatc ccgctgtttt
     4201 atcccgctgc ttttgcacca cttgttttaa gctttttctt gaatcgaaga gcagggatca
     4261 tggctggtat tttccaagca gtatccgcac ttttcatttt ttatgattcg attggcacga
     4321 actttctaac gattatcttg atgtcttatg ttttctctgg gctcatggca acgattgtca
     4381 gacgcaaacg gatctcagaa caaggattat ctgctgccat gtgggtcatt atttttcctg
     4441 tgatgatgga tgtcattttg atcgtctatc aaggaatgag ctttggtgat gcaacgactt
     4501 ggttaatgct cgtctgcggg ttcactggtg cactcttctc attcttgctg acgatcggtc
     4561 tacacccata tattgaattg atggtcaatg atgacagtgt aattgtatta aatgaactca
     4621 gcaatccaaa tcatccttta ttgaaacagt tgctggaaga agcgccaggt acttatcatc
     4681 atagtatgat ggtagctaat ctaagtgcta acgctgtagc agaaatcggc ggacgttctt
     4741 tgctaactcg agtagcttgc tattatcatg atatcggcaa gatcaaacat gctagctttt
     4801 tcgttgaaaa cttgccttca ggagcggaaa acccgcacaa tttcttattg ccagaagaca
     4861 gtaaacatat tatctttgga catgtgacag atggagccaa aatattggaa gattataata
     4921 tgccgcaaat ggtgatcgat atttgcaaac agcatcatgg aaccacgcta atgcgttatt
     4981 tctacatcaa agcgaaagaa cgcaatccgg aagtaacaga agagcaattc cgttatcctg
     5041 gaccaaaacc gcaaagtcgt gaagcaggga tcgtcaatat tgctgacagt tgtgaggctg
     5101 cagtacgggc aatggatcat ccgacgagcg aaaaaatcga aagttttgtc cataatctta
     5161 tcgaagagcg tatttccgat ggtcaattag acgatagtgg actgaccttg aaagaaatcc
     5221 gaaaagtgga aaaatcatta atcagcggtt taagtagcac cttccattct cggatcaaat
     5281 atcctaaaat gaaaacagaa gttgagaaga taaaggaagt acaagaagaa tagaaagaag
     5341 cgatgtataa tggatattac ctttatggat gaaacaaacc aagtctcaga agagaaaatg
     5401 aaagaaatcg atgacttgct gcaatttgca gcatcttatt taaagctgcc agaggaaaca
     5461 gaaatgtctg ttactttcat ggacaatgcg gcaattcaag taatcaatcg tgattaccgt
     5521 ggaaaagatg caccgacaga cgtcatcagt tttgctctgg aagaagaagg cgaagacgaa
     5581 atcccagtga tttttgaaga tggagagaat ccattacctc gtgtactagg agacatcatg
     5641 atctctattg aacgtgctgc tgaacaagca gaagcttacg gccattcata tgatcgggaa
     5701 cttggctttt tagcggtaca tggatttttg catatcaacg ggtatgacca tatgacacca
     5761 gaagatgaga aagaaatgtt tggtttacag aaagagatct tggatgccta tggactcaaa
     5821 agataaaaac gtagagaaaa acaaacattt cctgatgtct gtggaatttg ctgtccaagg
     5881 agtcaaaacc gtttttgagg aagaacgcaa tatgaggaaa catgttgcgt tcggtatcct
     5941 tgctttattt atgggcgtga ttttccagct tgatcggata gagtggttat ggctgctttt
     6001 agctgttttt ctcgtttgga tagtagagat catcaatact gtttttgaaa atgtagtgga
     6061 catgtttacg gattttcatt ttcatccgat tgggaaaaaa atcaaagata tggcagctgg
     6121 agcagtttta gtgaccgctt gttttgctgt catcattggg ttgattttat ttgtccctaa
     6181 aatatatcat ttgttgttta attaaaaagg agaacgtata tgccagaaca taaatcaggg
     6241 tttgtcgcaa tcgtcggccg cccgaatgta ggaaaatcca cattattgaa ccgaatcgtg
     6301 ggtcaaaaaa ttgccattat gagtgacaag gcacagacaa ctagaaataa aatccaagga
     6361 gtatatacta caccagaagc tcagctgatt tttatcgata caccaggaat ccataaacca
     6421 aagcatcgtc taggagattt tatggtagaa gcagcttaca gtgcgttgaa agaagtggat
     6481 gcagtcttat ttatgatcag tgctgatcaa aaacgtggcc ggggagacga ttttattatt
     6541 gaacgtctaa aaaacgtgca ttctcctgtt tatctgatta tcaataaaat cgataagatc
     6601 catccagacg agttgctggg aatcatcgaa gattattcga cgcagatgcc ttttgcacaa
     6661 gtgattccga tctctgctac agaaggaaac aatgtcgaac gcttaatgga tgtattagtc
     6721 agtgaaatgc cagagggccc acaatatttt ccagatgatc aagtgactga tcatcctgaa
     6781 tacttcatcg tttctgaatt gatccgtgag aaagtcttgt ttttaacacg agacgaagtg
     6841 cctcattctg tcgcagtcgt tgttgattcg atgaagcgaa acgagaatga taaaatccat
     6901 atccaggcca cgatcatcgt cgaaagagat agccaaaaag gaatcattat cggcaaaggc
     6961 ggaaaaatgc tgaagcaagt aggaacgaaa gcaagaaagg atatcgaaaa tcttttagga
     7021 gacaaagtat ttctagaact ttgggtcaaa gtccaaaaag actggcgaga caaaaaagtc
     7081 tatctgcaag acttcggcta ccgaaaagac gagtactgat attctggact tcttataggt
     7141 taggtataga aataaactgg ataaaaatcc gtacgttgag aaaaacagcg gaagatcgaa
     7201 acataaataa tctggatcgg cagaatctgc ttttccagat ttatttttta ggagggagaa
     7261 tatgagccag cttgtagaat cgaaaggctt gattttatct agccgtaatt acaaagaaaa
     7321 agataaatta gtcaaaatct ttacggaatc ttctggcaaa atgatgtttt atatcaaagg
     7381 aatccatcgg caaaatcagc cattagctcc ggctttgctc ccctttaccg aagcagtcta
     7441 tatcggtaat tttcgaagtg aaggtttgtc gtttttaagc agtgtcaaag acgtccatgc
     7501 gtttcggaac atccaagaag atatcttttt gagcggttat ggtacgtatt tgctaaatct
     7561 agtagatgca gcaatcgaag atcatcaata tgacccgcat ttattccaat ttacgcaaca
     7621 agctctgcag cggatggacc aaggagatga tgcagaaatc atcacgaata tctttgaagt
     7681 gcaaatactg caacgcttcg gaatcgcgcc aatttggacg cactgtgtcg tatgcgggga
     7741 aacaaaagga aaatttgact attcttccaa atatggcggt gtgatatgcg agaaacactg
     7801 gccaatggac gaacaccgtt atcatgcaga tcctcgcgct gtttatttcg ttcgaatgtt
     7861 ttcggctatt tcttatgata agatcagtgg aatccacttg aaagaagaaa cgaagcaggc
     7921 aatccgtgac ctcattgacc agttgtatga tgaatatgtc ggtattcatc taaaaagcaa
     7981 aaagttcatt gatcaaatga agtcttgggc acacgtatta aagacgccag agaaaaatat
     8041 gcctgaaaaa gagatacctg aaaaagaaga ataaatgaaa gatacaacaa aaaaatcaaa
     8101 actatttgac aaatacaggg acttccgtct attattaacc gtagattaaa tagatcgttc
     8161 actgagagga tctattatac aaaccagaaa actgcaaaat gaatacgtac attgaccaag
     8221 atcagtaaaa aacacgtggt ttagcgagtt cgggagagtg gaagccggac ccaaacgatt
     8281 tttgaagagg cacttgcgag tacgataaat gaagctgccg aatctttatt cggaagtagg
     8341 gtggaaccgc gaaattattc gtccctatgt ctgtaatcag acatagggac tttttgtcgt
     8401 tttctttcct gtattcttat tgacagcaac gcttaaaaat tgaaaggggc aaaacagatg
     8461 agtaaaaaat tgaccgtcca agatatgatt ttaacattac aaaaattttg gtcatcaaac
     8521 ggctgcatgc tgatgcaagc ttatgataca gaaaaaggag caggtacgat gagcccatat
     8581 acattcttac gggcaatcgg accggaacca tggaatgctg cttatgtaga gccatcccgc
     8641 cgaccagctg acgggcgtta tggagaaaac ccaaaccgtt tgtatcagca tcatcaattt
     8701 caagtcgtaa tgaaaccttc acctgaaaat atccaagagc tttatttaga aagcttgcgt
     8761 cttttaggaa ttgatccatt agaacacgat attcgctttg ttgaagacaa ctgggagaac
     8821 ccatcgatgg gttgtgccgg tgtgggctgg gaagtatggc ttgatgggat ggagatcaca
     8881 caattcacgt acttccagca agtcggagga ctaccttgta aaccagttac ttctgagatc
     8941 acttatggac tagaacgtct tgcttcttat atccaagaag ttgaaagtgt ttatgatctg
     9001 gaatgggctg atggcgtgaa atatggtgag atcttcaaac aaccagaata tgaacattct
     9061 aaatattctt ttgaagtaag cgaccaagac ctgctactaa gcaattttga tcgttttgaa
     9121 aaagaagcta aacgctgtat cgatgaaaat cttgttcatc cagcgtatga ttatattttg
     9181 aaatgtagcc atacattcaa tttattagat gctcgcggtg cagtatccgt aacagagcgt
     9241 gcaggttatc tttcccgtat ccgcaacatg gctcgtgctg tagccaaaat ctttgtggca
     9301 gaacgcgaaa aattaggatt ccctttattg aataaaaaca cagcaaatcc agaaaacgtg
     9361 aaggaggctg aataagatgg caaaagactt attacttgaa atcgggctgg aagaaatgcc
     9421 tgctcatgta gtcacaccaa gcatgaaaca attagaagaa aaaacagcaa aatttttaga
     9481 tgaaaaccaa ttgacttatg atacgatcga aacgttttct acaccgcgcc gcttagcaat
     9541 caaagtaaca aacattccag aacgtcaagc agacagcgaa gaagaagtca aaggaccagc
     9601 caaaaaaatt gctttggacg cagatggaaa ctggacgaaa gcagctgaag gatttgtccg
     9661 cggacaaggt ctgacgacag atgctatcac ttttagagaa ttaaaaggcg tggaatatgt
     9721 ctatgtaacg aaatacactc acggcaaaga agcaaaagaa gtattgacag gtttagcaga
     9781 tgtcattaaa agcctcactt tcccagtaac gatgcactgg gcagaatacg attttgaata
     9841 tattcgccct attcactgga tcgtggcatt gttagatgac gaaataatcc cgtttgagat
     9901 cttggatgtc aaaacagaca gagtttcaag aggtcatcgt ttcttaggcg aagatgtgac
     9961 atttacgcat gcaaaagaat acgaagaaaa attgaatgaa caatttgtta ttgcttcacc
    10021 gcaaaaaaga aaagaaatga tcatcacaca agcaaacgaa ttagcagaaa aaaatcactg
    10081 gatcattgat ctagatgaag atttactaga agaagtcaac aatctagtcg aatatccaac
    10141 tgtcttttct ggcgacttcg aagaaaaata tctatctgtt cctgaagaag tactagtcac
    10201 ttctatgaaa gaacatcaac gttatttcga agtacggaac gatcaaggta tgttgcttcc
    10261 tcattttatt tctgctcgta atggcgatcg ggtaaaattg gaaaatgtgg tacgaggcaa
    10321 tcaaaaagta ttgactgctc gtttagaaga tgcggaattc ttttataatg aagacaagaa
    10381 agcttcaatc gaccaatacg ttgaaaaatt aaaaactgtt actttccatg aaaaaatcgg
    10441 tagcatctat gagaaaatgc aacgggtaca agtcatcgct cgcatcatag gcgaacaagt
    10501 aggactatct gaggaagaat tgatggatct gcaacgcgct gctgaaatct ataaatttga
    10561 tctagtaacc aacatggtag gagaattccc tgaactacaa gggatcatgg gagaaaaata
    10621 tgctctgctt aaaggcgaga aaccagccgt agcaacagcg atccgtgaac attacatgcc
    10681 tatatccagt gaaggagatt tacctgagac tacagtaggt tctgttttag cgattgctga
    10741 taaattagat agtatctttt ctttctttgc agttgggatg atcccaagtg gctcaaacga
    10801 tccatatgct ttgcgccgtc aagcatatgg tgtcgttcga atcatcgaat cgaaaaaatg
    10861 ggcctttcct ttgtctgttc tgcaagaaac gattagtgaa gttatcagta aagatacgga
    10921 tcgttttggc attggcttgt cagcgggaca acaacaggtg atcgacttta tcaaaggccg
    10981 tctgcgccaa ttattgacaa cgaagaatat ccgtcatgat gtcatcgaag ctgttttgaa
    11041 tgcagaacaa aaagatctga caaaagtatt tgcagcagca caattgttca aacaacatct
    11101 tgcagatgaa gacttcaaac cttcaatgga agcattgaca cgtgtcgtga acttagcgaa
    11161 aaaagcgcag cttgaaaaac aatcagaagt agaccctgag ctgttcgaaa acgacgcaga
    11221 gaaagaatta cacaaagcag tagaagcaat gaaagcaagt tttgctgacc aaacgatcca
    11281 cgaaaactac gaccagcttg tcgctcttcg tccactgatc gaaaattatt ttgatcaaac
    11341 gatggtcatg gctgatgaac cagcagtacg taagaaccga ctaacacaac ttagtcaaat
    11401 aactgccatg gctttgtcat tagcaagctt ggatcaaatc atcacaaaat agtcttttgt
    11461 ttgaaaaaca gagagcatgc acgaaacgtg ctgtgtctct gtttttttgt tataaatata
    11521 aaagctgtta ttaattctat tttaataatt tttgttattt tattctttgc tagaattttc
    11581 aaaacgctca tgaaaagtga ggaaataaaa atgaaaaaga ttaataataa tcttgttact
    11641 gttttattta cttttaaatt aggaatttcc ctagtcaaga aaactgtttg tggtatgatt
    11701 atatagggaa aacctgttta taaatatttc tatgaatata ttagtttaat tatgctttta
    11761 aaataaaaag cgctcattct gatgtgaatg aatcacatct ttatttatct atcatcaata
    11821 tttaggagtg aatctatgga aaagccgttc gtcaagttat tggctactgt ggcggtaggc
    11881 acaggcgcta ttgtgatttg cttgtttgga taccatctca ataatcagcg gcaacatcat
    11941 caacggatca attacgcaga atctgccatc accaatcaaa aagacaccgt gacctcttta
    12001 tcaaaagaag tagataagct gtacagtaca aaagaaaaaa ttttcctaaa tcctgaaata
    12061 acagaagaaa cagtttcaaa tttgtcacat aaactatctt ctatcaaact ttcagcagat
    12121 gattatgaca tcaaggaatc agaattacct aaagaagctg ctgcgatcca agaagaaaag
    12181 aaagcagtct taacacagtt agaggatgca gaatcaaaac tgaagatcca aacggctgtc
    12241 aataaattat ttactaaaaa cgtatcaaac tggcagcaag ctgtggatga tgtcatcatc
    12301 aaagaaaagt tggcaagtgc agatgtcgcc catgtacgtg aaaatatgag cttttttaag
    12361 gatagtgctt ggaaaacggt cgttatgcaa tatctaggat tcgctgatac ccaaattgca
    12421 caagtcacgc aactagatca gctattcgat acgatgctga aagacggtca agtaacagct
    12481 actgctactt acgatcaata tttgaccgca ctcagtctca tcgaacagat ccggaatgaa
    12541 aaaataagag ccgcatacgc gtcaaaagca gaaacagtcg ctcagcaaat gggctatagc
    12601 aatacgagct attaataagc gagaattcaa gcaaggctag caaacggagg aaactatggc
    12661 aaaacgaaga agaagatcaa gagggaaaaa gatatttcta attattttag caattcttgt
    12721 cgtattagta ttagcaatcg taggagtagg agcaaaatta tatctagatc tctcacattc
    12781 tattgaaaaa acttacgaat cagtggaacg aacccaagga gaacgaacaa aaccagttga
    12841 tctggacaaa caagaatctt tctctgttct attgatgggg attgatacgg gagatttagg
    12901 tcgggtcgat caaggaagat cagatacgat gatggttgcc acagtcagtc ctgaagacaa
    12961 acagacaacg attgtcagca ttcctcgtga tacgtatgtc gacatcgttg gacatgacac
    13021 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
    13081 acaaaaatat gtagacatcc caatcgatca ctatgtttca atcaatatga aaggtctaaa
    13141 agaactcgtt gatgcagttg gtggtatcga agtcaataat gacctcacct tctcacaaga
    13201 tggctatgat tttacgatcg gtaaaatcac attgaacggg gatcaggcat tgtcttattc
    13261 tcgtatgcgt tatgaagatc caaatggtga ctacggcaga caagaacgtc aaagaaagat
    13321 cgtagaaggt gtagcgaaaa aagtgttgag tctgaacggt gtaagcaact atcaatccgt
    13381 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaagat
    13441 tgctttagat tatcgggatg catttggtac gatcaagcaa gatcagctgc aaggagaagg
    13501 cttcatgcaa gacaatatct cataccaaaa agtcagcgat caagaacttg atcgtgtgaa
    13561 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
    13621 agagacaatc agcttgaaag aaatttttga aacattacgc aaacacgtga taacaatcct
    13681 catctcaatg tttgctggct tggccatctc aggcatcgtg acgtttttca tcttgacgcc
    13741 aaaatacagc tcacaagccc aattgatcgt gacactgccg caatcagata ctgcaaatgt
    13801 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaggatatga tcgtcagtga
    13861 tctagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtaa aaatgactgc
    13921 tggacaaatc aaagatgcca tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
    13981 ccaagcaaca agcacaaatg cagtgacggc tcaacaaatc gctaatacaa cgtcacaagt
    14041 attccaagag aacgccaaag acgtgatgaa tgtcgataaa atctcgatca tctcaggtgc
    14101 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
    14161 gttaggaatg atggtaggcg taggtctagc tttcttattt gaattactcg accggacagt
    14221 aaaagatgaa aaatatgtga cggatacatt gggcttcccg atcttaggga ctgtaccaga
    14281 aatgtcagcg aaagaattga atgctggtat ccgtaaaaaa ggaccagctc cgacacaacc
    14341 aaaagctaca aacgataaaa cagcgccatc acgcagaagc cgctcaagag tctaggagga
    14401 aagaaaaatg gcacgaacac agaaacaaaa agcagcccaa actcatgcag tcagtttggt
    14461 cacactcaca aacccctctt caccaatcgc tgaacaatat cgtacgattc ggacgaatat
    14521 ccagtttgcc tccgcagctg gtcagcaaat taaaacgatt gttgtgactt catcaggacc
    14581 tggagaaggg aaatcgacca ctgcagcaaa cattgccgtt gtttttgcca aatctggtca
    14641 acgggtgctg ctagtcgatg cagacttacg taagcccgtc atctataaaa cgttcaagtt
    14701 gaacaacgca agcggattaa gtaccgttct tagttcatca ggaagtgtag cagatgagat
    14761 ccaacgaaca ccagtcgaga atttgtcgat tctgccaagt ggacctaaac caccaaatcc
    14821 atcagaacta ctaagttcgc caagaatgga tcagatttta gcagaagcaa gacaactatt
    14881 tgatgtagtg atcttcgaca tgccgccagt agttgccgta acagatgcac agatcatgtc
    14941 ttccaaaacg gatggcacct tattggtcgt acgtgaaaat atgtcacgga aagaatcatt
    15001 gactaaagca aaagaattgc tggatatggt acaagcgcga gtccttggtg ttgtatacaa
    15061 tggggcagaa cacagcaaag atgctggcta ttactacggg aattaagaaa taaaaagaga
    15121 ggagacaaga gaaatgatcg atctacattg ccatatcctg ccaggaatcg atgacggagc
    15181 agaaaacata gatgccagta tcgccatggc tgaaaaagcg attcaacaag ggatcacaca
    15241 tattttatgc acaccccatc ataataatgg aaaatacagc aatgaaaaat cacaagtcat
    15301 ttctctagtc gcttcgttac aagcagaatt agagaaaaga caattgcctt tgacgttatt
    15361 ggaaggacaa gaagtacgta ttaccggaac actgatcgaa gacatcgacc gagatgaaat
    15421 tttatttaca gatttagatg atacatatct tctaatcgaa tttccgacac tggaagtgcc
    15481 gttatatgca gaacagctct tttttgagtt gttacaacta ggaaagacac cagtgatcgt
    15541 ccatccagaa cgcaacgcgc attttcgtaa agacccgaat catatgctgc cattcctaga
    15601 tatgggatgc ttggcccaac tcaccgcacc aagttatgtc ggtgtatttg gaaaagacat
    15661 ccagaaaaca gccaaaatga tggtcaaaca taatcttgtg cagatggctg cttctgatgc
    15721 ccatggggtc tctaagcgca ccttttactt aaaagagtgc tataagcaga ttgccaagga
    15781 ctttggtaag gaaaaagtag tacagatgaa acaagtcgca aaggatctga tcaacgggga
    15841 tgaaatcagt tatccagtct atgaagagat aaaaaagaag aagtttggtt tattttaggg
    15901 ggagtgtaag gtgtttgtat taacaagaag aagaaaaatt gccacattgg ttgttgtgga
    15961 cagtttgtta ttgatcgctg caaatattgc agcagctaaa ttcatgaagc cgtttgtagc
    16021 tataccaatg gaccttattt taatctctac cggtttgtcg attggttttt atttatttta
    16081 tggtagttta ttcaaagttt tcactcggat caatcgctat acaaatttaa gagagatcat
    16141 tgcaattttt ggttcactat ctgcaagtga cgtctcaagt atcctcatac tgctgttcat
    16201 taatcggcaa tacagtttac ggttagttat ctttgcttat ctgctttcgc tcttattgat
    16261 catcggtagc cgattgatct ggcgtatcta catcgaaaca aaaaatatga gatatgtatc
    16321 agcggattct gctaaaaata cattgatcgt tggtgctggc gaaggcgggc gtattttata
    16381 caacagcttt ctgggatcca aaacggctca agatatccaa gttgtcggat ttgtagatga
    16441 tgatccgaat aaaagaaata cgtatctttc aggaaaaaaa gtattaggtg cattaaaaga
    16501 tattccggaa ttgattgaaa aatatgacat tcaaatggta acgatcgcta tcccttcctt
    16561 atcaagaaaa aaattacgaa gaatcttcga gttagtcgaa tccgctcacg tgaaagtcaa
    16621 cacgatgcct tctatagaag aacttgcttc aggaaaaatt agcgtatcaa aattaaaaac
    16681 aattgacgta gtggatttac tgggaagaga tgaggtaaag ctggatattg aatccatcaa
    16741 agatcagatc acagacaaag tcattcttgt caccggcgca ggaggatcga tcggttcaga
    16801 aatctgtcgg caaatcattc aattcaatcc tgcaaagcta ttgcttttag gacatgggga
    16861 gaactcgatc tacttgattg accgtgagtt acgcacgcat catcaaaatt gtcctacaga
    16921 aatcgtaccg atcatcgcag atatccaaga tcgcgagaaa atcaatgaga tcatggaaca
    16981 atatcatcca gatatcgtct accatgcagc tgctcataaa catgtaccac tgatggaata
    17041 taatccaaaa gaagcagtca aaaacaatat tttcggtaca aaaaatgtag cagaagcagc
    17101 taaagcagca aaagtgaaaa acttcgtcat ggtatcgaca gataaagcta acaatcctcc
    17161 aaatgtcatg ggttcaacaa aacgaatcgc tgaaatgatc gtgactggat tgaatgaaga
    17221 aggctgtacg aaattctcag ctgtcagatt tgggaatgtc cttggttctc gcggtagtgt
    17281 gattccagta ttcagagaac aaattgctaa aggtggtcca atcactgtaa cagactttcg
    17341 tatgacccga tacttcatga cgattcctga agctagtcgt ttagttattc aatctggcgc
    17401 attagcaaaa ggtggcgaaa tttttattct agatatgagt gaaccagtga agattgtaga
    17461 cctagccaaa aacatgatcc gattgagcgg gtatagcgaa gacgaaatcg aaatcattga
    17521 aacaggtatc cgtccagggg aaaaactata tgaagaacta ctgttggata aggaaagaaa
    17581 tgatgaagca gtttatgaga aaatctttgt aggaaacatc aaaggttact caatacaaaa
    17641 agtgatggat tttgtcaaga gcctgccgca agacgatgaa caattggcta aagatatcgt
    17701 cacttttgca aatgcttcga ataaataggg gggaaatata aatgaataaa ttagaaaaac
    17761 gtcagatacc attttcaccg ccagatatta ctgatttaga aataaaaaac gttgtagaag
    17821 tattaaaatc tggatggata actacgggac caaagacaaa aaaattagaa aaaaaaatta
    17881 caaagtggtt aggaacttct aaagtagttt gtttaaattc acaaactgct gctgcagaaa
    17941 cagggttacg tttgctggga ataggagaaa atgatgaggt tatcgtccca gcttatactt
    18001 attctgccag tgcaccggtt gtatgccaca taggcgcgaa cctagtatta atagactgtc
    18061 aacaagattc tttggagatg gattacgatg cattagaagc agcaattacg gagaagacaa
    18121 aagtgattat tcctgttgat cttggtggta taccttgtga ctacgaccgt atttttgaga
    18181 ttgtggagaa aaaaagaaat ttatttcaac ctagtaatga gattcagaaa gcttatggtc
    18241 gtataattgt tatggcagat tctgctcatg catttggagc taattggcat gatcagatgg
    18301 ttggtaatgt tgctgacttg acaacatttt catttcatgc tgttaagaat tttacaactg
    18361 cagaaggtgg agctttagta tggaaagagc acgacaaact agataatgag gcaatgtatc
    18421 atcagtgcca gctgctttct ttgcatggac agtcaaaaga tgcacttact aaaacacagt
    18481 tgggtgcatg ggaatatgat attgtgggtc catggtataa atgtaatatg actgatgtta
    18541 ctgcatcaat tgggttggca caatttgaac gctatcctaa tattctgaaa agaagaaaga
    18601 atataattaa gaggtatgat gaagcctttc aacaactagg aattgaagtt cttatgcatt
    18661 atacggatga ttatagttct tcaggccatt tatatattac tagagtacct aacattagtt
    18721 ctgagcaaag aaatgaaata attataaaaa tggcagaaca agggattgct tgcaacgttc
    18781 actataaacc acttccaatg tttacagcat ataaaaatat ggggtttgat attaataact
    18841 atcctaatgc ctatgctcat tttgtaaatg agattacatt accattgcac acgaaactta
    18901 cagatgaaga agtagaatac gtaattaata actatagtaa gattgtaaag gatttggttg
    18961 gatgatagga gaggcaaaat gagaaagtgg gaagatttgc caaaagaaat gcagaatgat
    19021 gaaatacggt attattatga tatcctcagt aaaaaaaaat tcagcttagt ggtaaaaaga
    19081 gtatttgata ttttagtgtc tgcaactttg ttactgacac tttcatggtt attttttatt
    19141 cttgcaatag tgataaaaat tgattctcct ggacctgtat tttatagaca agaacgtatt
    19201 actcgttatg gaaaaaaatt taaaatttat aagtttcgta ctatggtaat aaatgcagat
    19261 aaagatggca ctcttgttac tgtgaaaaat gatgatcgta ttacaagagt aggaaaggta
    19321 atccgtaaat atagattaga tgaaattagt cagctaatta acgttttggt cggagatatg
    19381 tcttttgtag gaaccagacc agaagttgga aaatatgtaa agtcgtattc accattaatg
    19441 ttagccacat tattattacc agccgggatt acatcagaaa ctagtatttt atacaaagat
    19501 gaagataaat tgttgcatga taaaaataac atcgacaaaa cttatataga aaaaattctt
    19561 cccagtaaaa tgtattacaa tttgaaaagt atcagtgaat ttagttgtat gaatgatttg
    19621 aaaataatgt gtaaaactat ttttgttata tttggtaaag aatatcacgc cgacttagaa
    19681 ggtgaacgag agtttattaa tcagataaaa tgaatggagg ataagagttt tggtgattga
    19741 agagataaaa agttcggata aagagttaat taattcgatt gtcgatattc atatgagaac
    19801 atttacaaat ttttttttga ctttcatggg aaaaaagttt ttggaattga tgtatcgttc
    19861 ttacacagaa tataatgatt ctggtatatt ggttgctatt caaaatgata agccaatagg
    19921 atttcttgca tattctggag atatgagtgg tttatataag tatatgataa agaaaagaat
    19981 aataccgttt ggattttata gttgtgtagc ctttataaag aaacccaata tccttatgag
    20041 gctttttaga gcttttctaa aaccaagcga aacaaaacgt gatgaaaatt atgtggaatt
    20101 agcatccatt ggagttaatc cgaaagagaa atcgatagga gtaggttcca tgcttataga
    20161 taacttaaag agtagaattg atttttcaaa atatgaatat attgcactag aaacagatgc
    20221 attaaataat gatgttgtga ataattttta taaaaagaat gagttcattt tagaacgtaa
    20281 atattctact aatgaaggaa gaattatgaa tgaatatcgg ttttatatgg agaagaatta
    20341 attatgaaat tattgtatat tttaaatgta gctaataaag taaataactt ttctaaagct
    20401 agtatgatgg cagctaaaca aacgggttta gaattttata tagctggtaa ctggaaatac
    20461 aaatccgatg aggaaagaaa agctgatgaa gtgaaatatg gaataaaaat ataccaagtt
    20521 gatttttata gaaacccact aaatttaaaa aatataaaag cttatcatca gattgtagag
    20581 attataaaaa atgaaaaaat agatattatc cattgtaata cacctattgg aggtgttgtc
    20641 ggacggattg ctggtcttaa atgtaaagtc aaaaaagtaa tttaccaggc acatggattt
    20701 catttttatt caggtgctcc taaaataaat tggtttatat attatcctat ggaacgttgg
    20761 ctagctcatt atacagatgt tttgattaca ataaatcatg aggattatac tttagctcaa
    20821 aaacttcgtc ttaggaaagg tggaaaagct tattatattc caggtgtggg tatagataca
    20881 aataggttta tgtcttccac atcaataagg aattttagag aaagtatatg taaagaactt
    20941 aatatacctg atacagcaaa aatcatttta tctgtaggag agctaaatga gaataaaaac
    21001 catttatcag taatacatgc attacaaaaa attccgctgc atacagatat ctattatatt
    21061 atcgctgggg taggagaaat gagggagaca ctacaaaata ttgctaatga attaggatta
    21121 catcagcgag tttttttact aggatataga agtgatatac ccaaattatt agctgctgca
    21181 aacatatata ttctaccctc attaagggaa ggcctcaacg cctctttaat ggaagcgatg
    21241 gctagtggtt taccatgtat tgtcggtaat ataagaggaa atgtagatct tatagaagat
    21301 ggtaagggtg gatttctaat caatcctaaa gacgaagaag aaattgctgg tgcgataaat
    21361 agattggctg ataacaaatt attgtgtgaa tctatggggg cacataattt agacaagata
    21421 aaagattttg atttatcagt tgtgataaac caaataaata atgtttacca tgaaattgta
    21481 agtaaataat tgaattgaaa gtgatattaa tatgaaaaaa ataaaaatta tgcatttgtt
    21541 gcaaagta
//
LOCUS       DADQCX010000046        21468 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.046, whole genome shotgun sequence.
ACCESSION   DADQCX010000046 DADQCX010000000
VERSION     DADQCX010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.046"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            56..757
                     /locus_tag="J8R83_001580"
     CDS             56..757
                     /locus_tag="J8R83_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9574710.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1329..2345)
                     /gene="tsaD"
                     /locus_tag="J8R83_001581"
     CDS             complement(1329..2345)
                     /gene="tsaD"
                     /locus_tag="J8R83_001581"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAZ9574711.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2342..2806)
                     /gene="rimI"
                     /locus_tag="J8R83_001582"
     CDS             complement(2342..2806)
                     /gene="rimI"
                     /locus_tag="J8R83_001582"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAZ9574712.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2813..3355)
                     /gene="rimI"
                     /locus_tag="J8R83_001583"
     CDS             complement(2813..3355)
                     /gene="rimI"
                     /locus_tag="J8R83_001583"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAZ9574713.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3339..4163)
                     /gene="tsaB"
                     /locus_tag="J8R83_001584"
     CDS             complement(3339..4163)
                     /gene="tsaB"
                     /locus_tag="J8R83_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAZ9574714.1"
                     /translation="MYHCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDKIIVPMFDARRKNVYAGAY
                     RWKENRLEIVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFYEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(4252..5232)
                     /locus_tag="J8R83_001585"
     CDS             complement(4252..5232)
                     /locus_tag="J8R83_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9574715.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5256..6740)
                     /gene="galT"
                     /locus_tag="J8R83_001586"
     CDS             complement(5256..6740)
                     /gene="galT"
                     /locus_tag="J8R83_001586"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAZ9574716.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6752..7741)
                     /gene="galE"
                     /locus_tag="J8R83_001587"
     CDS             complement(6752..7741)
                     /gene="galE"
                     /locus_tag="J8R83_001587"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAZ9574717.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            7990..8157
                     /locus_tag="J8R83_001588"
     CDS             7990..8157
                     /locus_tag="J8R83_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAZ9574718.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8219..10030)
                     /locus_tag="J8R83_001589"
     CDS             complement(8219..10030)
                     /locus_tag="J8R83_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAZ9574719.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10027..10392)
                     /locus_tag="J8R83_001590"
     CDS             complement(10027..10392)
                     /locus_tag="J8R83_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAZ9574720.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10555..10950)
                     /locus_tag="J8R83_001591"
     CDS             complement(10555..10950)
                     /locus_tag="J8R83_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAZ9574721.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(10968..11930)
                     /locus_tag="J8R83_001592"
     CDS             complement(10968..11930)
                     /locus_tag="J8R83_001592"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAZ9574722.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(11930..12142)
                     /locus_tag="J8R83_001593"
     CDS             complement(11930..12142)
                     /locus_tag="J8R83_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAZ9574723.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12163..12861)
                     /locus_tag="J8R83_001594"
     CDS             complement(12163..12861)
                     /locus_tag="J8R83_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAZ9574724.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(12881..13423)
                     /locus_tag="J8R83_001595"
     CDS             complement(12881..13423)
                     /locus_tag="J8R83_001595"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAZ9574725.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13555..14559)
                     /locus_tag="J8R83_001596"
     CDS             complement(13555..14559)
                     /locus_tag="J8R83_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAZ9574726.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14556..15545)
                     /locus_tag="J8R83_001597"
     CDS             complement(14556..15545)
                     /locus_tag="J8R83_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAZ9574727.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15542..16348)
                     /locus_tag="J8R83_001598"
     CDS             complement(15542..16348)
                     /locus_tag="J8R83_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574728.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16514..17470
                     /locus_tag="J8R83_001599"
     CDS             16514..17470
                     /locus_tag="J8R83_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574729.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17547..18065)
                     /locus_tag="J8R83_001600"
     CDS             complement(17547..18065)
                     /locus_tag="J8R83_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9574730.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18153..18302)
                     /gene="rpmG"
                     /locus_tag="J8R83_001601"
     CDS             complement(18153..18302)
                     /gene="rpmG"
                     /locus_tag="J8R83_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAZ9574731.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18530..18976
                     /locus_tag="J8R83_001602"
     CDS             18530..18976
                     /locus_tag="J8R83_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAZ9574732.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19171..21066)
                     /gene="asnB"
                     /locus_tag="J8R83_001603"
     CDS             complement(19171..21066)
                     /gene="asnB"
                     /locus_tag="J8R83_001603"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAZ9574733.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6456 a         4563 c         3705 g         6744 t
ORIGIN      
        1 attctttaaa aaaagtgaca ataaatatag tgaacaataa ggagaggact ttttaatgcg
       61 tgttaataaa atcgattttc acttttcaaa actcagatat caacctgatt ttgaacattt
      121 ctcggatgaa gagttccaac agatcaagga acatactgtt cttcgttctt ataaaaaagg
      181 acagatcctt ttcgacgatg gtgatcccag acaacggttg tatatcttga ccaaaggact
      241 cgttcgttta gaacgttatg atgaaagtgc aacttattac tactatgact atgtgaatac
      301 aaataacctt tttcctatgt caggaatgtt tggagaagag acctacactt atacagctca
      361 agcgatgact gatattgaaa cattctacct tcctgtttcc tactatgaaa aattagcacg
      421 aaaaaatccc gaacagttga tctatatgat acaaaaaatt tctaaagtag ttgaaataca
      481 tgaattgcgt atccaaatcg gattgacctc tagcgccttt gaccgggtaa aacaaaattt
      541 attcattttg aaagaagaat tgggcgtacc aacaaaagat ggtcatatca ccattcctta
      601 tccgatcacc ttaaaagaat tagcagtgaa tagcggcacg acacgtgaaa ctgctggaca
      661 agtaatcaaa caactacgtg attccggact gttagattat gacaaaaagc gttttacttt
      721 ctgtaagaca gctactactc cagctatgag agaataacgc gaacaaaaat aagcagtgac
      781 cctgatattt atcagggtca ctgcttattt tcctccctaa aacttctgaa agatccggca
      841 gttttagatc actgggcaag actcaaagat tttctatgtg tgtttcagtt atgtaatatt
      901 cactgtttgc aaaaaatact gatagattaa ctagaggaag cgtcttgtcc tcatccgacc
      961 tagattattc gatattcctc gacaataaac gattaatcag tgagggcaat cagaggaacg
     1021 gataatgatg aataagctgt aaaaaatagg gctttgacaa aagcgtgtca cagcccttat
     1081 ttcgattaaa cggtgtgtac ctgtcaactc ttcggtcaca agtcataatg ttcataaaca
     1141 tgaggagctg ttttttgaaa ttgttccttg tgaatcagag ttaaacgaca ggcttacgaa
     1201 ctcttgatta aacggcgttc aaaagcttgc atacgcggta ataagaacag ccaggtcaaa
     1261 aacatgagaa gccgtttttc ctgggctgtt cttattactt gatgcagggc agatttttca
     1321 caacctcttt attcagataa aaccaagctt ggatcagcat tcaactgata gctagcaaaa
     1381 tttctttttt gcatttccac atgtgctgct gctccaatca ttgcagcatt atctccacaa
     1441 agtcgaagag ggggaatcac tagttctacc tcagggagtt tagttgccaa agcatcctgc
     1501 aatccttcac gcaacccttg attggccgct acacctccag ctacaatcag ttgcttgact
     1561 ggataatttt gacaagctcg aagtgtttta gtaatcaata catcgatcac acttgcttga
     1621 aagctagctg ctaaatcatt tttgtctaga tcttctccac gctgttgtgc attatgcacc
     1681 aaattgataa atgcactttt taatccgcta aaactgaaat cataattatc ttcatggatc
     1741 atcgctcgtg gaaaatggta attatctttt ccctgatgag ctagctgatc gatttctttt
     1801 ccgcttgggt aagaaagacc taatactctt ccaactttgt cataagcttc tcctgctgcg
     1861 tcatctcttg tctccccaat gatttcatat gatccatctt cttgcatata gactaattct
     1921 gtatgtcctc cgctaacaag aagtgccatc aatggaaact ggaatggttt aaccagacgg
     1981 gctgcataga tatgccctgc catatggttt acaggaataa gcggcaattg gtgtgcccaa
     2041 gcaaaagcct tagctgcaga aataccaatc agcaacgagc cgacaagtcc tggtccataa
     2101 gtgacagcga ctgccgataa atcttctgcc gacacaccag cttctaccag tgcatcttcc
     2161 aagcataagg tgatttgttc tacgtgatgg cggctagcta cttcaggaac tacgccacca
     2221 aaacgtttat gactgtttat ttgagaagca acgatgttag ataagatctc tgttccattt
     2281 ctaacgaccg ctacactcgt ttcatcacaa cttgattcaa tcgccagaat caattcttca
     2341 ttcatttcat cgtctccgtt tttaactttc tgctcataat gatcgcatct tccgtcggat
     2401 tgcgataata tgatttccgt ttacctaata tacgaaactt ttctgattca taaagttttc
     2461 ttgctgcttc attagataga cgtacttcta aaaaaacatg cagcgaatct tttatttgtt
     2521 ccgtaatcag taattgtaac aaatgccgtg catgcccttt tccttgttct gaaactgcaa
     2581 cagcaatatt tgtgatctcg acttcatcta ttactttcga gtatccaata aagccacaga
     2641 tctggttatc ttcaactaaa agcagataat cagagtgagg ctgttggatg tctgccaaaa
     2701 actgcatttt cgtccaaggt gaaccatgtg gataagcatt ttcgctaatc atccatacgc
     2761 attctgccaa gtacgcttca tcaaaatctt tttttctgca aatcaactaa tctcactcat
     2821 tttctaaaag ttttatcata tccaacgcat cttcttttgt ttcagtgtaa tatctttttt
     2881 tgatcgttgt tgcttgaaaa cctaacttcc gataaagtct ttgtgcatct tgattactca
     2941 tacgcacttc taatgacatc gtctcacagc gattcattat agcaaagttc tcgatttcgt
     3001 caataagcag cgaaccgatt cgtttacgct gatatgccgg tcgaacggca atattcgtga
     3061 tatggcaatc taaaccgaac gctcttgaac cgataaaacc aatcattctt ccattatcaa
     3121 agatacctag atatagatga ggaagcggtg acttcaattc tgatataaag gcactttttg
     3181 tccatggcaa ttcgccatta tagacttctc gttcgacatc cagcagctct ttgatatctt
     3241 ctgtagtcaa ttctcttagt acgtaacgac gatcgatttg ttcgattgtt ttttctgtat
     3301 aaatcatttt atcttgaaaa aagcttctgg catacgctct aaattttttc aacataactt
     3361 tcgtctccag gtgtgtgcgt ctccaaccat ttttcttctg cttctacccg ttttaaatag
     3421 cgaggaagaa aagcttgttt ctctgcaact ggttcagcta aagcacctaa ttgagccaca
     3481 gttacaccac ttggaatatc ccatgctgga actgtattaa tcatcgcact aggcaatatt
     3541 tcctttattt catagaagaa tttgtgacaa tcactcccga cgaaataaat agcttcattc
     3601 agcttttgta gttgtgtgaa caaatcagaa gcagaaatat gtacatcttc aagtacaatt
     3661 tctaatctat tttctttcca gcggtatgcc ccagcgtata cattttttct tcgagcatca
     3721 aacatgggca caataatttt atccacaccg atgcaattag ccgcgatggt tttcagacta
     3781 gatactccta ctagctcttt atctaatgta taagcaatcg tttttgctgt cgttacacct
     3841 atacgaagcc ctgtataaga accgggacca tcagaaaccg cgattcggtc aatgtctttt
     3901 ggacttattt gaagatctgc aaacaattgg tcgattgcag gcatcagtgt tacactgtgg
     3961 ttgcgtttga tatttgtttg tatttgtcca agaatttgtt cgtcttctac cacaccgatc
     4021 gccaaagttt ggtttgcagt atctattcct aatgtaatca tatatttgat cctttctgct
     4081 atgacattct cgccttccat tgtagcatac ttttttattc tgaggatgaa aataccaaag
     4141 gcaaaactag tacaatgata catgattatc tgctggcggg caaattttgc cccttcctga
     4201 aacacaaaaa agctgcggta tcacttcatt tccccacagc ttttccatct tttatttcgt
     4261 tgattctcga ataatcaact ctgtttccac aataatcttt cttgaaaccg gtgctttgga
     4321 attacttaat tgaagaatcg tctccactgc tagctctccc atccattcgg tataaacttt
     4381 tacagtagaa agagagggcg ttacatattt cgctacactg acatcattga aacccatcac
     4441 agaaatatct tctggtacca ctaaaccttt ttcttgaatc gctttcagtg cgccaatcgc
     4501 taatgcatca ttagctgcaa aaagcgcatc aggaacatgc ggattcgttt ttaaatactg
     4561 cttcactgct tgatatcctg actcgacaga aaaatctgct tcgataattg gaccttcgtc
     4621 gtagcctttt tctgccaaaa cttgttgaaa tgccataatt ctgggatctt ttagccgctg
     4681 atggtttttc ttcgtatatt ctgttccagc aagcatagcg atatgttgcg ctttatggga
     4741 gacaaaatgt tcaatgactt tttgaacact tgacttaaag tcgacaacta gagagtcgat
     4801 tccttgagaa gtgccgtcag aatctaccaa aagcaaggca ttttgggatc ctttcatttc
     4861 taataactga gcttcgtcga attttcctag tgcgatcgtt ccatctgtcg gaagatcact
     4921 aatggaatcc cacgtttctt tcaataaagt aacgtttgct tcttctgcct ttttttcgat
     4981 tcctagacga atagataaat aataaagatc ttcaagctct tccgtatcgt cgtaccactg
     5041 gatcaggcga agcgtttgct tagtatttgc tgcattttta cgatgtttcg tataatttaa
     5101 gcgttctgct gcttcaaaaa ttttttgctt tgtggctaag ccaacggaaa gatcaggatc
     5161 atagttgaga actcttgaaa cagtagcagg agaaactcct gccaactgcg caatgtcttt
     5221 aattgttgcc atttgtctct cctccttttt tacgtttata aaattgcagt aaatcgttca
     5281 aacgctgcct gtcctttttc atctcgcttg aatactccag cgtcttccag tacacgtgca
     5341 aaaacctgac ctacagattt ttgtacgaca tcggtgaccg tatctttcgt caaatcagga
     5401 tgttcttttt ttaattgttc tgcccacgga cgatgatatt cagccatctg gttttcttct
     5461 cctaataaga aatgctctac ttctactagt tctggtttca aacgaggtgg taaaacagca
     5521 agccccatta cttcgatcaa cccaatgttc tcctttttga tatgttggac atctttatgt
     5581 ggatgaaaaa tcccatcagg atgttcttct gaaacattgt tgtctcgaag gacaaggtcc
     5641 aactcaaagt aattgtccct tcttcgtgca attggcgtaa tcgtatggtg tggtgtacca
     5701 tctgctgaaa aagctctgat agatactgtt tcatccgaat atgctttcca cttttccaat
     5761 actgagttag ctgcttcaat caacaatttt ttctctgttg attgcaaacg gatcacagac
     5821 atcggccatt tcacgactcc tgcgatgact tgcggataat ctgctagttt gataagtttt
     5881 tctatcggtg cttttgccat aggaaattca tgacgtcctg cctgataatg atcatgagaa
     5941 agaatcgatc ctccaacaat cggcaagtca gcattcgaac caacaaagta atgaggcaag
     6001 acttcagtaa tccgaagcag tctagcaaat gtttcctttg tgattttcat cgggcggtgt
     6061 tgttctgata aaatgatcga atgttcattg taataagcat aaggagaata ttggaatccc
     6121 cagctttcac cgtctagatt cattcgaata atccggtgat tggtgcgggc tggatagttc
     6181 aagcgacctc tatatccttc gttttccatg caaagcatgc aggtaggata gtctactttt
     6241 accgcctcgc gttctgctgc gatttgtttt ggatcttttt ctggcttaga taaattgatt
     6301 gtgatttcca gttcaccata ctccgactct gccggaaatt tgatgttttt tgcgatggct
     6361 cttgttttga tgtagtcatt tttcttactt aaattaaaga aatactcagt tgcttcctct
     6421 gggcttttcg aatagtgctg tgcaaagaat gcattgacga ctgaaggtgg cggtgtgaga
     6481 aaatccatta attgcgcttc aaaaatctct tgttctgctg gcaattctga aagaacacca
     6541 ttttctcttg ccttagcgac aagctgatcc aataagtcta cagattcttc cttaactggt
     6601 cttacttcaa tgctttctag agcatcttct cctaccatcc ctaaaagacg attctgtaaa
     6661 tataagcggt ccatttccat ccatccgcca gcttcgatcg caagtgtggc aaaatcacaa
     6721 atcgtttgac tgattgacat atctcattcc cctattcttc ataaccattt ggatggctga
     6781 catgccaatc ccatgctgtt ttgataattg ctttgatatc tgtgtattca ggtttccaac
     6841 ccagaacctc tctcgctttt tcacttgaag cgactaatcg gctaggatct ccagctcttc
     6901 ttggtgctat ttctgctgga atttcttttc ctgtcacttc tctagctgct tctagcattt
     6961 ccttgactga gtatcctttg ctgctgccta aattgaagaa gttgctttca tttccttctt
     7021 tcaagtattc caaagctaaa atatgtgcag caatcaaatc ttctacttga acataatctc
     7081 tgatacatgt tccatctggt gtatcataat cgtctccata aacagccaat gcttttcttt
     7141 gaccaagagc tacttgtaaa atgattggga caagatgcgt ttctggtgta tgatcttctc
     7201 cgatagatgc atctgctttt gctccggcta cattgaagta gcgcaaagcg acatagcgca
     7261 tgccatatgc ttggtcacac cacttcatca ttttttccat catcaattta ctttcaccat
     7321 acggattttt aggattagct ggtgtatctt ctgtgattgg agactctttt ggttctccgt
     7381 aagttgctgc agtagaagag aacacgattt tattcacatt gaactcgtgc atgacttcaa
     7441 gtaagatttg cataccgtat acgttgttgt tgaaatacat caatggtttt tcgacagatt
     7501 ctcctactaa agagcttgca gcaaaatgga ttactccttc aatcggttcc ttttcaaata
     7561 cggaacgtag aaattcttta tcccggatgt ctccttcata aaaatgagca tctggatgta
     7621 ctgcttgttt gtgacctgtg agcaaattat ctaccacagc tacttgatac cccttttgaa
     7681 ctagctggtc tacagcgtgc gaaccgatat aaccggctcc gcctagtact aaaattgtca
     7741 taaaaaacac tcctttgatt agtaaaattg tgtttgttga ttatatataa tttaaaaaaa
     7801 cgaagtttac ttttatggtg aaaacaaaca aagtaaaatt tcgtaaattc atatggtaaa
     7861 tttataataa aacatttagt aaacattttc aaggattttt tgcaaaggtt tacaaacaaa
     7921 cgtaaaacta gccttttttt ctcttttgtt ccataataga tataacaaat aataaatgag
     7981 gtggattcaa tgaaaaaatt tgtatctgga atattagtag gaagtctggc aacagccgct
     8041 gccgttgctg gtttggtcgc ttctgtgaaa aaaacagtga tcgatccaat tgacgaaaaa
     8101 gaagcaatga tcgaagaaaa ccgtaaaaaa gcaatgcgca aacgcgtttc tcgttaataa
     8161 ttatttaaaa acacgcatga agacttgtga aagaacagat aagtcatcat gcgtattttt
     8221 atttgtcagt caatataagt tgtgctattt tatctgcctg tctcagattc catggatctg
     8281 tataaggtct agctactgct gcagttagcc aatccacacc ttcaacaggt attccatagc
     8341 aataaaagtc agactggatt tcccctgaag catcaatcac gcgattcgta cctcgctcaa
     8401 catctatagc ttctgaatga taacttcctg tattatctga aaatgaaaaa gggcgaacaa
     8461 gtttgttttc cttcaaattt tttatgacag gattacttga acgagaaaag cttgtttgtg
     8521 gcaatcgagc ttcaatcaaa tagcgactgc tgatttcttt atcttgtaga gaaataacat
     8581 agcggttgtg cttttgctga atatcaaatg gcggttcgaa caaatgaaaa atacccgcat
     8641 ctatcagtgc tgctaattct ttcgtccgaa tgactggcgg accgatcgtt aaaaagctat
     8701 ttagatgagt aaaccatccc catagtattt ctttgtattc ctttgcagaa aaaacgtgcc
     8761 attcaatagc ctgccggatt ggatcacgcc agtcttttaa tgcatcaaat gttgaagcaa
     8821 atgctcctgt gcaattgcct ttttccgctt cttttatctg cccttcaata aatgctcggc
     8881 tagcttctgc aaaggactca tcctgatagg taagaggaat ttctaaatac gaccaatccc
     8941 atctataagg gattagtgct ggatgctttc cgagacactc ctctgaagag agggagagaa
     9001 aatcatgctc aaaatttttc tttggaatcg gcaaatgata ttcttcgatg attttcttgt
     9061 aataaaacaa ctcaacgtct tttttcagat agtcaaaaaa tgtttcgcca gtcaaaaatc
     9121 ccgactgatg ccattgctcc aggttttctt ttgttagtaa ccgtggccat gccattgatc
     9181 cgccttgctt ttggtttctt cctcgagggt aataagggag cccccttctt gatccactgt
     9241 atacaatcgg ttccttgcct gatggatgat agacaagttt tcctttttcg ttctcgaagc
     9301 gcccttctct tgatactgta aacaatccga cataatcaaa aaaacttaag cctagacctc
     9361 ttaaaaagac attttcttta ggcggtatct tcgaaagatc gacatctgca ggattagaag
     9421 gaagctgata cagtaaatca tttttctttg cgtagtctac ccacactctt tcttcttctg
     9481 tctcatcatt ttcccagtga ccgcttgcta aaacaagctg atcgatagaa tagctttgct
     9541 gatctgtctg taaaagataa ccatcttttc ttttgctgac tttttttact aaagaataaa
     9601 caaactgaat agaagctgga aattcttctt gcaactttga gaaaaaccag cgttgataga
     9661 gtccgtataa acatcgagta gattgctgat ctttttccag acgattgatt tcttctataa
     9721 ttagttgctt atttttggtt accgtctgtt cgatataatc tgtagcaggt cctttactcc
     9781 attgaaacaa gttgggtccc tgtgttacca atcctccact ggacaatgtt tcatctgtaa
     9841 aaagcgtcac ttgttgagaa acagaattca ttaataactc cggtggctga ttcaaccgcc
     9901 aaactcgacc tccaggacca ttgggatcga aaagaaaaag ttcaagagaa tgtctgtcct
     9961 gattattatg gagaatcctt tctgctatac ttaatcctct aggtccggca ccaatgatcc
    10021 ctattttcat ttgcatgcct ccatttcgat aaattttttc aataaaacag catggttctg
    10081 atgttcattt tttgcaccat aaacaaaagt aatgactgga tgttctttca taagttgact
    10141 gagtttaaaa atagcttgct tcttttcttc ttcgaaaatc aattcttgct ggtatttctt
    10201 tgcaaatgaa gcaaatcgtt ctggtacatg gtcaaaagtt ttgcgtgctt cattactagg
    10261 tgcaatttct ttcaaccaca gatctaactg cgctttttct tttgaaattc ctcgtggcca
    10321 gaacctatcc acgagtattc tatagccatc ctctttttca gcatcaaggt aaacacgttt
    10381 taatttgatc atagttgttt ccttctttct gccttttcgc ttagcttata tatgtagata
    10441 atagcacaaa ataaaaaaaa tgaacggcac aactatccat tgcgccgttc atgtgatctt
    10501 ggtcaaaatc taatgattga ttcggttttt aaagctgtca tacaatcatc tgttttatac
    10561 ttttttactt ttgatttttc cagaccatcc gtcatatcca cccttaagta aataaatctc
    10621 ttgataacct gctttacgta atttatttgc tgtacggatg ctcaagcttt tcttttgatc
    10681 gtaaatatag acaggctggt cttttcgaat agatcctaat gaatctttca aaacagtgta
    10741 agggatgttt cttgcaccta aaatatgccc agcatcaaac acatcttttt cgcgaacatc
    10801 gattacttgt gcttttctca ttccttctcg aaattcttct tctgtcaaag tcgttgctga
    10861 acgcttggcc attactcgta gatagacttc ccaaaagatg attgcaagca caatcaatag
    10921 caaaatgata ttaattaccc ataaaaccat gtaatgcctc cgttttttta agcaaatttc
    10981 aaggctaatg aggcagcacc aatgacacca gcttcattac caagctctgc taatttgatt
    11041 tttgttgatt ctcttacttg cgggaaagta aattctttaa aatatttctc tacacggcta
    11101 cgtaaaaatt ctcctgctgc cgatactcct ccacctaaca caatacttga cggattcaat
    11161 gtattcccca agttggcgca agctaaacct aagtagaagc atacgcgatc aacaaccatc
    11221 aatgcaaacg gatcgtcttc ttgagccatt tcaaagatat ctttacttgt tacttcttca
    11281 ccgttgtcta acattgcttt cagttttgaa tctcctgcgt attcttctgc caagtaacga
    11341 cctagacgta ccacaccagt agcgctagac acagtttcta aacatccgcg tttaccgcaa
    11401 gtacattcga acccttcagg atccacagtg atatggccga tctctccgcc tgctccgctc
    11461 acgccgtgaa tcaaatttcc gccagcaacg ataccaccgc caacacctgt tcctagagta
    11521 acgaatacaa cgtctggatc gttttctcca gcacctttcc atcgttcacc taaagcagca
    11581 acattcgcat cattatcgat agcgaatttg attcctgttc ctgcctcgat cagttttttc
    11641 acaaattgaa cttctgtcca gtttaagtta tacgcaccaa taaccgttcc agcttcgctg
    11701 tccacgcttc ctggggtacc catgccgatt ccgataaagt cttcggcttt catattatat
    11761 aaattcaaac gatggttgat tgattcaatg atttcaggaa cgatatgctt accatcatcc
    11821 aaaatattgg tatcgatgct ccatttttgt tgaatctctc cttctggtgt taaaattgca
    11881 aattttgctg ttgttccacc taaatcaatc ccaataatct tcttgtccat tacaaatttc
    11941 ctttctttcg gctttcttca attcggtgct ctctttttaa tatgcgccac gctgtcatgt
    12001 atgtatcatg atcaatcaaa cggctatcat acagattacg caattcgata gtcattaatt
    12061 caatgtcata gatgcgtgca cccacataga taaagatgcc aaattttttg aacagctgct
    12121 gtacatcata taagctctcc atctttaagc acttccttca tattatacaa gtaaaccata
    12181 tttttttaaa cccagtaaaa tacatattac aaaaagaaat acaaaaacta gtgtagaaag
    12241 aatcctttgg tgtatcgaat agcttgtctg ttgtttcggt agacccaaaa cattccctaa
    12301 cactaatccg ccaattagcc caccgacatg tccccaaaca tctacagagg tatccagaag
    12361 accaaaaaca aatgtcaaca caataaataa aagaaaatgt ctgactagct gctggatcgc
    12421 tgggttatgt ttaaaatgaa accctaagat aaacaacgca ccgaacaaac cgaatatcga
    12481 agtactcgca ccaccagaca gaacattcgc ttcgttaaaa gcaaagcttg ctgtatttcc
    12541 cattatcccg ctgaacatat aaatcaagaa aaaacgccaa tggccataga ttgcctcgat
    12601 ttgctgcccc ataaaataca gtatcagtga gttcattacg aaatgcatca gtccaaaatg
    12661 gatgaagatt ggtgtcacta aacgccacca ttcattgaag tgaacaagat aaggaccata
    12721 cattccggca taataaggga tctcaagtcg cggaaataat tccatcatga ggaagaccgc
    12781 tgtctgtatc cctaaaaaag cataggtcca taacggtcgt cttaaccatg cacgcaattt
    12841 tatttgctgt tgataattca tgaaaacctc ccatttcatt ttagtcaata aacaattgtt
    12901 ggatcttctg atcaaagctc tccggttgcc attgttcatt caattgttca cgaaaaacaa
    12961 ggctacatgt ttttttatga aaattattta aataccggtc gtaataacca ccgccaaaac
    13021 cgattcgata accggctcta ttgtagataa tacctggtac aatgaggaga tcgatcatct
    13081 ccggcaaata gagcttctct gattgtggct caagaacacc aaaactcgaa cgtacaagaa
    13141 cggactgttc atccatttca taaaacgcca tctgacgttt cggcaaagtt ttaggtacaa
    13201 ctattttctt ttgttctttt tctgctcgtt ggataaccgg ctgtgtatcc agttcaaatt
    13261 cattcgataa agtcgtccct atcacttttg ctgacttcca gtactcgctg gcgaatagct
    13321 gtttatagat tcgctgttct ttttcctttt tcttgccact tttggccaga tttttcagct
    13381 tttcgattcc tttccggcgt aatcttactt tcaattggtc caaaaactca cccttccttc
    13441 tctcataaaa tggtatagga aaaaaagaaa aatagcaatc gaactttcaa ataaatgcat
    13501 aaatagaata aaaagaagac ctagaaatga ttggccttcc ttttttaata aatttcaact
    13561 gttcagcgcg tgtttttgtc tgataaaaag tgcatacaga aaatatggcg caccaaaaag
    13621 ggcaatcaaa attcctgtag gtacttcccc acttggtaga atcactctag caaccatatc
    13681 tgcactaagc agaaaaatgg aaccgaacaa accgctcaga acaaaggtcc agttattttc
    13741 tttacgtacg actagcttcg cagcatgagg agctagtagt cctacaaaag ataaactacc
    13801 tgtcaccgct acactaccgc ttgccaaagc aacagctaac aacaaaagga ttttttgact
    13861 tttagccacg ttaaggccta atccttgcgc gcgttcttga ccaaatgata gcaatccaat
    13921 cctctgtgca taaagtcctc ctagcggaat taagataacc gcccatggaa gcaatgccca
    13981 aacataaggc cagctcgcac cccagattga tcccgctaac catgcattca caaatccata
    14041 attttcctta gataattgga tcgtgcatag caatgttaat gcagaaaggc cggcattaac
    14101 ggcaataccg gacaataaga ttcgattcat acccaaaaag ccatttcgat cataggccgc
    14161 aagatagaca cagcaagcag ctaaaacacc acctagaaag gctacaacta gcaatagaaa
    14221 cggcagcgaa tagtgcgaaa agaaacctaa ataaagcatc actaaaaatc ctgctccggc
    14281 attaatgccc aatatactag aatctgccaa ttcatttctt gttactcctt gcaagatata
    14341 accagaaacg ccaagacaag ctcctgctaa taaactgatc agtaatcgag gaactcgaaa
    14401 ttctctaaca atcagcgcca aagaagatga ttctttccct atgaacgtgg caaaaagctg
    14461 atccaggtaa ataaaaggcg taccaatcat taaactacct atagacagga tgacaagtac
    14521 aaaaagcaag aaatagaacg tccaatatat ttttttcacc gttgttccct ccttacttgt
    14581 atcagtaaaa acggaacgcc aatcaatgca atgactaatc caaaaggtgt ttcaaaaggg
    14641 ggattgatca tcctcgctgt aaaatccgcc aacataacca atccaccgcc aactaaaaaa
    14701 gagacaggta gaacataacg atagtccgtt ccaaccattc cgcgaacaac tggcggaacc
    14761 aacagcccaa taaatgaaac aggtccgact aacgaaacgg caatggctgc taacactgca
    14821 actagacaga aaacaatcaa ccgcgttcgt ttaggatgac ttccaagagc taatgcatgt
    14881 gtttcactca aatgaatcaa agatattgct tttcctaatg aaaaagaaac caaaacagca
    14941 agtatatata aaggaaacaa tactgctaat tgtttccatg tgatattggc agctccgcct
    15001 acaaaccaaa aagcaagatc ctgctgcaga ttaaagaatt gggtaagtgc ttggctgata
    15061 gcagtaaaaa aagaactaat agctacgcca gctaaaatca gctgtaaagg attcatgccc
    15121 attttcgaaa actgcaaaaa accaaatacg agcaaagtta cagcaaaaga acctgccaat
    15181 gacattagaa acacagaaaa atcagaagct ttaggccaaa aagcaaaact aagggccatt
    15241 gccaacgaag cacccgcgtt gattcctagt aagcctgaat ctgctaaagg atttcttgtc
    15301 actccttgca tcaatgcacc gctcaatgca aaacaactcc ctacaagaaa tgctcccgcc
    15361 acacgaggca aacgaatatt tcgtatgatt tggtgacttt gttttgatct atcaaaatca
    15421 aacaacgcct gccaaaaatc tgcttttccc acagtcgctg cgccatttga aagagcaaca
    15481 aaaaaaataa tcaaaagaac aaaacagacc aaaagcagga gtctattttt cttcatagtc
    15541 ctcataattg atcctcctgc tcttttggca acaaatcata ggttagaaaa actggtttat
    15601 ttgttcttgg aagcgtgaca atcgttgcat caatctcaaa tatttttttc atacactctt
    15661 ttgtgatcac ttcttcaggt gtaccttctg tgatcaactt accgtttttc attgctaata
    15721 aataatctga aaaacgtgaa gcatgattaa tgtcatgaat cgacatcaag atcgttgttt
    15781 gtttcatttg attgatttca gtcaataact gtaggatctc taattggtgt gccggatcta
    15841 aaaatgttgt cggttcatcc aagatcaaga tatctgtttc ctgagcaagc gccatagcga
    15901 tccagacacg ctgggtttgt ccaccagaca gcgttgcgat atcccgcata cgaaatccag
    15961 ctagacctgt agcatccaac gcccactcga ttgcttcatg atcttgcgtg tccatgccac
    16021 tgaacagttt ttgataaggg tatcgtccgt aagatactac ttcttctact gtcatacctg
    16081 tagggtgttc actagtttgt gctaataatg taattttttt tgcaagttct tttgaactgt
    16141 atgtagagat atcagagtta ttgacaatga tctttcctga tttcacaggt agtatacggg
    16201 taaaactttt caataaagta gattttccac ttccatttgg cccaatcaaa ctagtgattt
    16261 tcccttcagg aatcgtaaca gacatgtttt caatgatttt tttgttttcg tagccggctg
    16321 caatgtcagc tgctcttaat ctcgtcattt cacccatcct ttcgctgaaa atcattctca
    16381 attatgacgc tgtttcaaca tttcgtcaag cgctactttc atatctatag ccaaatgaag
    16441 cggttgacag cgttcgaaat atcaggaata ataaccaatg agaaagattc tcaattatgt
    16501 taggaggaaa gaaatgaaat taaaaacaaa agtattcaca ttatctagca tattgctgct
    16561 ggctggagta ctgagcgctt gctccccctc ttcagataaa gaaacagcta caactgccaa
    16621 ttcgacgact tcatccaata gtactcatac agtcacagat acacttggac ataaagtaga
    16681 gattccaaac gcgcccaaac ggatcatcgg cagttactta gaagactatc tgattgcact
    16741 aggggaaaaa cctatcgccc agtggactgt tggcagtggt tccattcaag attatctgca
    16801 agatgattta aaggatgtcc caacgatttc ttatgacctt ccttatgaga aagtgttaag
    16861 ctttgagcct gatttgctgt tgatttcttc ttccgctact gtcgaaggcg ggaaatacga
    16921 acaatatagc aaaatcgcgc caacttatgt tgtaaaaaac ggaacagatg tcacatggga
    16981 agaacaacta aaagatgtcg gcaaagcttt ggcaaaagaa aaagaggcag aaaaaatcat
    17041 ttccgattat caaaaatcca tcaagaaaac tcgagaagaa ctagcagata aaatcgagaa
    17101 caagacagct gcagtgttgt gggtgaccaa caactcagcc tttatggtca gcaaaaatcg
    17161 gtcaagtgga agaatcgtat acgacgatct ggaatttggt gttcctgatc tagtggaaga
    17221 ggtctccaaa aaagccactt ctgactggtc tgctgtttcc tctgaaaagc tagctgaatt
    17281 agatgctgac tacatcatcc ttgtgaacag tgacaaagat gctgccatgt tcaatgaacc
    17341 aagctggaag aatcttaaag cagtgacaga caatcatgta ctgcaattcg gacctgaatc
    17401 tagttggcta tataacggac ctattgccag tcaggaaatg gtcaatgata tcaaagaaaa
    17461 actaaattga ttttaactaa aaaaagaatc ttcacgatta gtcgtgagat gctttttttc
    17521 ttattaacaa actagacgca tagattttat tcttcttttg aagcaaccct attttttact
    17581 ctttcccatt tttgaaaacg atgggcatat agattttctt gatccgttat cccctcatac
    17641 tcctctataa gggcgaagtc tgaaaaatca atattcccaa tatacgtatc gccttcaaac
    17701 gtgctatcga tcaatgttcg ccagatccga ccagtgtaag gaagaagttc ttgaaaaatc
    17761 cgactaccac ccgaaacata gatatcttct gagatcgttt gactatacga caaaagttca
    17821 tcgatcgaat gcattacttc cgcattttct ttcgtgcgaa aatttggttg cgttgtcaac
    17881 acgatgatat ggcgataagg aagtgaaaga tcccccattc cttcataggt ctttcttccc
    17941 atcactaaaa ttcgatccat tgtatgttcg cgaaagaaac gcatatcatt tggcaatcgc
    18001 catggtaaca aaccattttt gccgatcaga ccatttttat cttgtgccca catggaaata
    18061 aacatattat ccgctcctta tgattttaga tgttttgaga taaaaaaagt ctcaattctt
    18121 tgaccagcaa ggaattgaga actttaaaaa cattattttg tttcacggtg caaagtaact
    18181 ttgcgttcgc gtgggcaata tttttgtttt tccaaacgat caggattgtt acgtttgttt
    18241 ttgcttgtta gatagttacg ttctttacaa gaagtacact ctaaagtgat gtttacgcgc
    18301 atgtttttcc ctcccatttt tacaagaatc ctctaagatg actctcagac ttgattatct
    18361 taccatgatt ttttctagat tgctagtgtt tttcacgatt ttgttaagta aaactacttg
    18421 acgataaata caacggtttt acttctcaaa caaaatcttt ttctttttgt ataaataccc
    18481 ttacacttgt ttatatagat tatgtttttt aataaagggg gatactaata tgccatggaa
    18541 catgaaggac tttcctgcat caatgaaaaa cttagataaa ttgacaagaa aaaaagcaat
    18601 cgacatcgca aatgcattat tagatgaagg gtaccctgat aaccgtgcga tcccaattgc
    18661 cattgatcaa gcaaaaaaat ggtatgaaga tgctagtgaa tcagaaaaac gaactttcga
    18721 aaaagaaaaa aatccaagca agacggatga acacgatacg aatcctcgtg ctggaaaact
    18781 gcttgattca gatgtgatcg tagaatatga ggaagaacaa tggatcgtga aatctaaagg
    18841 ggcaaaaaag gcaagcaacc attttgatac aaaaaaagaa gcaatcgaaa aaggaaagca
    18901 agtagcacaa aacaaagaat caactttgtt catttataaa aaagatggga caaaagaaaa
    18961 agaaatcgat tattgaacat atgtaaaggg gttgtgacga aaatcgtgtc acaaccccct
    19021 tatgttcgaa acaatggtgt tcctctgcca actccgaacc ataagtcata atatctataa
    19081 aacgggaaga gctgtttttt gaaattgttt cttatcactc agtgttaaac ggtaggagaa
    19141 aacctctttt ttattgatat ttgattttca tcaaacagtc acatagtcga ttgcttctgc
    19201 ttgcggaatc gtttcatcta caaagtagac tttataccat gtcaagaaac tgaagattgt
    19261 ccagattttt ctttgctctt ctttacgtcc ttcgtgatgg tcatctagca acttcatgat
    19321 tttttcttga tcaaaaaatt cttttgcaaa atctgcttcg aataatgctt tgacttgttc
    19381 gtagccgtgt tcttctttca accaagcttt gattggcaca gggaatccta atttcacacg
    19441 attcgaccat tcttccggaa gatgtttgtt cgcagcttgt ctgaaaatat cttttgtgtt
    19501 gttttgattc aataaaaact tacttggtat ttgttgagcc aatttcatga cttcgatatc
    19561 caataaaggt actcggactt ccaaagaact tgccatagaa agtttatctg cctttaacaa
    19621 gatatctttt ggcatccatt gatgaagatc gacatattgc atcttattga cttcatcttt
    19681 gattccttct gttttctcgt aatgaacagt catgatttca tccacagatg gtgctgtttg
    19741 atattttggt gttaacactt ctgatgcttc tgattcttcg aacactcgag catgaccgat
    19801 aaaatattct tttgcaggag caagtgattc atataaatgg atccgtccat ggaaattttt
    19861 catttttccg attttacgtc ctaaattata gcgtgttcct tttggtaatt ttttcaatcc
    19921 ttgagcaatc acacggatga attttgaatt cgtatggaat ccatacgttt ggtatcccgc
    19981 aaacagttca tccgcccctt ctccagattg gactacccgc acactttgtg aagcaagatt
    20041 tgctaaaaag tacaaaggta cgcaagaagg atttgaatca ggttcatcta agtgatactg
    20101 gatcaaaggg aatgctttga acgacatgtc tccgtcgatc actgctgctg tattatctaa
    20161 gtccaatagt tcggttagtt ttctggcttc aatcgcttca ttataggttt tatcatcaaa
    20221 cccgattgag aaagaatgat ctggtttcaa tacagaggtt acataactgg aatcaacccc
    20281 gctggataag aaagaaccaa cttctacatc actgaccgta tgtgcttcaa tagaagcttg
    20341 aacggtttcg tcgatttttt cgatccattc ttgtcgggaa tgcgtttctt ttgtttcaaa
    20401 atctgcatcc caatattgct gaatgtctag ttttccatct ttatacgtat aataatggcc
    20461 ttcaggcaaa cgatagacat ctttgaagaa tgtttcgccg tttaatggag aatattggaa
    20521 agtcatataa ggtttcaacg cttctttgtt caattctttg ttaaaatcag gatgaggcag
    20581 aaaacttttg atttctgaac caaacataaa tgttccgttc atttctgcat aataatatgg
    20641 tttgatccca aagtggtctc ttgcaccgaa taactcattc ttttcattat cccaaatagc
    20701 aaaagcaaac attccgcgga tcttttgcaa taattctgtt ccccattctt cgtaaccatg
    20761 caaaaggact tctgtatctg catgtgtttg aaaaacgtgg ccagctgcaa tcaattcttc
    20821 tctcaaaggc tggtaattat agatttcgcc attaaaaata atgatctttg tccgatcttc
    20881 attgtaaata ggctgagtac cgccctctaa gtcaataata cttaatcttc tgaatcctaa
    20941 agcaacatgt ttatcgatat attctcctga actattaggt ccacggtgaa cgattcgatc
    21001 catcattgta ttaataattg tttttttgtt gtccttgtcg ttaacaaaac ctacaatacc
    21061 gcacatttaa ctttcacatc ctaatataaa attactgttt atttcattca tatgcatctt
    21121 atcatagaat aaatagcgga cgaatatttt ctctcttaca atttcgtcac gtgaaaacaa
    21181 aagatgaaag tttctgtttt tacagaaaat aaagtcccaa tatctaattt accatgtttt
    21241 cttttttgag gctaccttat tctcttcgtg ttaaaaaaat attagtggat gctatttcca
    21301 aaaaaaacag caaaaaaaga cacgacctaa agatcgtgtc taattatgac tgtatcagaa
    21361 aatatgatac caaacggatc tattcattaa ttaattgaca tagtttatct gttgctcttt
    21421 tatgactgga taactgacca attcatgacg atccaagtct tctttatt
//
LOCUS       DADQCX010000047        21309 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.047, whole genome shotgun sequence.
ACCESSION   DADQCX010000047 DADQCX010000000
VERSION     DADQCX010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.047"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            68..808
                     /locus_tag="J8R83_001604"
     CDS             68..808
                     /locus_tag="J8R83_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9574734.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="J8R83_001605"
     CDS             complement(1232..1402)
                     /locus_tag="J8R83_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9574735.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="J8R83_001606"
     CDS             complement(1596..1775)
                     /locus_tag="J8R83_001606"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574736.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            2162..3274
                     /locus_tag="J8R83_001607"
     CDS             2162..3274
                     /locus_tag="J8R83_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9574737.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="J8R83_001608"
     CDS             complement(3352..3645)
                     /locus_tag="J8R83_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAZ9574738.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="J8R83_001609"
     CDS             3813..4127
                     /locus_tag="J8R83_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAZ9574739.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="J8R83_001610"
     CDS             4148..6127
                     /locus_tag="J8R83_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9574740.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="J8R83_001611"
     CDS             6140..6466
                     /locus_tag="J8R83_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAZ9574741.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="J8R83_001612"
     CDS             6482..7000
                     /locus_tag="J8R83_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574742.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="J8R83_001613"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="J8R83_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAZ9574743.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="J8R83_001614"
     CDS             complement(8436..9941)
                     /locus_tag="J8R83_001614"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAZ9574744.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="J8R83_001615"
     CDS             complement(10033..10623)
                     /locus_tag="J8R83_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9574745.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="J8R83_001616"
     CDS             10802..12448
                     /locus_tag="J8R83_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9574746.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="J8R83_001617"
     CDS             12497..13216
                     /locus_tag="J8R83_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAZ9574747.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="J8R83_001618"
     CDS             13695..14642
                     /locus_tag="J8R83_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9574748.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="J8R83_001619"
     CDS             14654..15574
                     /locus_tag="J8R83_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9574749.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="J8R83_001620"
     CDS             15615..17072
                     /locus_tag="J8R83_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9574750.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="J8R83_001621"
     CDS             17417..18031
                     /locus_tag="J8R83_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAZ9574751.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="J8R83_001622"
     CDS             18024..19748
                     /locus_tag="J8R83_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9574752.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKKQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="J8R83_001623"
     CDS             19745..21196
                     /locus_tag="J8R83_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574753.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         6869 a         3608 c         4317 g         6515 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagcaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tcttctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaattcc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggct aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtattttca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattga tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact atacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctgaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaaaca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaagg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tggaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaaa aaaagccaat gtaatgaaat aacttataaa aaattgtcta
    21241 gaaatctaat tttgggctgt tcttattact tgaggcaagg cagctttttc atgacctctc
    21301 gataaacgg
//
LOCUS       DADQCX010000048        20888 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.048, whole genome shotgun sequence.
ACCESSION   DADQCX010000048 DADQCX010000000
VERSION     DADQCX010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.048"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            84..3362
                     /locus_tag="J8R83_001624"
     CDS             84..3362
                     /locus_tag="J8R83_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAZ9574754.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3903..5810)
                     /locus_tag="J8R83_001625"
     CDS             complement(3903..5810)
                     /locus_tag="J8R83_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAZ9574755.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5940..6815
                     /locus_tag="J8R83_001626"
     CDS             5940..6815
                     /locus_tag="J8R83_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAZ9574756.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6895..7869
                     /locus_tag="J8R83_001627"
     CDS             6895..7869
                     /locus_tag="J8R83_001627"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAZ9574757.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8058..9194
                     /locus_tag="J8R83_001628"
     CDS             8058..9194
                     /locus_tag="J8R83_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAZ9574758.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9331..9675
                     /locus_tag="J8R83_001629"
     CDS             9331..9675
                     /locus_tag="J8R83_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAZ9574759.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9946..11232
                     /gene="efmA"
                     /locus_tag="J8R83_001630"
     CDS             9946..11232
                     /gene="efmA"
                     /locus_tag="J8R83_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAZ9574760.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11370..11969)
                     /locus_tag="J8R83_001631"
     CDS             complement(11370..11969)
                     /locus_tag="J8R83_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAZ9574761.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12373..13494
                     /gene="mnmA"
                     /locus_tag="J8R83_001632"
     CDS             12373..13494
                     /gene="mnmA"
                     /locus_tag="J8R83_001632"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAZ9574762.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13740..15161
                     /gene="arcD"
                     /locus_tag="J8R83_001633"
     CDS             13740..15161
                     /gene="arcD"
                     /locus_tag="J8R83_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAZ9574763.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15175..16293
                     /locus_tag="J8R83_001634"
     CDS             15175..16293
                     /locus_tag="J8R83_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAZ9574764.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16353..17645)
                     /locus_tag="J8R83_001635"
     CDS             complement(16353..17645)
                     /locus_tag="J8R83_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9574765.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17795..18355
                     /locus_tag="J8R83_001636"
     CDS             17795..18355
                     /locus_tag="J8R83_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9574766.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18484..18861
                     /locus_tag="J8R83_001637"
     CDS             18484..18861
                     /locus_tag="J8R83_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAZ9574767.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18794..20866
                     /locus_tag="J8R83_001638"
     CDS             18794..20866
                     /locus_tag="J8R83_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAZ9574768.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
BASE COUNT         6766 a         3790 c         4466 g         5866 t
ORIGIN      
        1 aattttgttt tttattgaca gtaaaaataa attaggtaat actttaagta aacgctttct
       61 aatttgttac gggaggaata cacttgttaa aaaaacgtat aaaatacagt gcgctaatga
      121 tgaatctcct tatgctcagt accccggttt taatttctgt cgttgaagtt gctgctaacg
      181 aacaacagtc tgtgaacgaa gaaaatgcac acgtgaacat tgaagggatg tcaacaatgg
      241 aggaaatacc aagaactagt gaagatatgg atacggaaga aggaaatgat cctatgatga
      301 aagaatcaga aaatgaaaag acaaaaaagc aatctgaaga agcaaatgaa gagtggaaag
      361 gggttgtttt cggagaaagc acaagtgcta gtaggtatgc cattgaacca ttagaagacg
      421 gcgtgcggct ctcttccacg aataacggcg gaaaattcca gtcaagcgga tcagatggaa
      481 tgacctatta ttatcaagca atccccaaag acatcaactt taggatgcgg gcgacgatcg
      541 aaatagaatc ttggacctat acgaatgccc aagaaggatt tgctttaatg gtaagagacg
      601 cagtaccaaa aaatcatttg tttgggcagg cattttattc aaattcattt gccatactag
      661 gcagtcggat cgaatatgtc tgggactcgg atagacaaga agtggtcaac acgagcggca
      721 gcaaatatac gatgcgactt ggattgggga cacgggcaat cacaggaata tcatctgaag
      781 atccgcaagc tgcgccagct cctgggagtg tctcagtgga aacaacacct ttagagactt
      841 cagcagggtt cttggaaaaa gaaacaggtt cttataatat attcggaaac ggtcatggga
      901 atctgtttcc ggccacgaac tcgattacta aactggacgt agagatgaaa aaaacgaata
      961 ctggtttaga ggcatattat tacgatcctg aaacaggaga agaaatggct tctgacatca
     1021 tgtatgactg ggaaaaatta tacgcttcag atgaatcggt tatttatgca ggatttgctg
     1081 cagcaaggaa tatgacgatc aaggtagaag gaatcgaagt tgcttactca gatcctgcga
     1141 cagatcctcc tgggcaagaa agacctactc gcttgattga tccgatttac actgtgacct
     1201 ctagtaatca ttcaggaaac caagatcata ctatgtcctt tagagcaaat gctgacggat
     1261 tattgacaat taaaaataaa gcaacaggag aggtgcttaa gaacgcaaaa aacttggcta
     1321 tcactgcgaa tcgggaattt gattatcaga caaaactgat ggaaggaacg aacgaattta
     1381 ctttcagttt tacgccagat aaaaactatc cgccagaaga atacgtagag atgactagtt
     1441 atgaaacaaa agagattctt catacagtgg actaccgtaa acctaaatat tcgacagttt
     1501 atgtaacacc agaagggtca gatgcaggaa acggaagcag acaaaatcca ttatctctga
     1561 cacaagcatt gagatacgca tatgctgggc agacaatcgt catggcgcct ggaacttatt
     1621 ccttcgaaag aggattgacg attccaaaag gcgttaacgg gacaagagaa aacccgattc
     1681 agttgattgc agagaaaaat ccagaaaaca agcgtcctgt acttgatttt aaaggaactg
     1741 gaaatgggat gacactgttc agtcactact ggggtttacg agggtttgac attacaaata
     1801 gtgcagctat gcaaaaagga ttacagattt ctggaaatca taatttgatc gaagagattc
     1861 atgcttatcg gaatggaaat acaggaatcc aaatcagcgg tagctcaaat gatcctttcg
     1921 aagcatggcc cgcgcataac ttagtcaaga actgtacatc ttttgaaaat gccgatccag
     1981 gatttgaaga tgccgatgga tttgcggcca aactgacaat aggagaagga aatgtatttg
     2041 acggttgtat cgcgtatcat aatgcagatg acggttggga cctttttgct aaaaatgaaa
     2101 caggttcgat cggaaaagta atcatcaaaa actcagttgc ttatcgaaac ggctgggtac
     2161 caggaattga gggagaaggt aacggtaatg gattcaaaat gggcggttct tctttaacgg
     2221 gccctcatga attgatcaat agtttgtctt tcgaaaatct tgcgaaagga atcgattcca
     2281 atagcggaac agatattatc gtcaatagca gtacaagttt taataacggt tcatataatg
     2341 tggctcttta tacctcttca gcaggaaaca cagactacca tgcttctggt atcttatctt
     2401 tccgaacaga gaatcttgag atgagagagc agatccgccc attgaatcaa aacgaagatc
     2461 aaatctacca ctcgttgaac tactattgga atgaacgaga gaaacaatca gaaaatactc
     2521 ttggacatac catatcaaaa gattggatcg agtctctaaa tacatgttcg aaagaaggtc
     2581 agcagcctgt tacgcgctat gaaaatggaa gtatccatgt tcatggactg atgcagatta
     2641 aaccggggaa tcgtcaaaca gaaaaggaaa gagtggatgg tcttccatta tctgtaggtg
     2701 ctatttttga cggagaaacc tcaccgtctt cggaatatcc agagtatgca atcgtacaag
     2761 aaccaaatca gacaaaacca aatgaacaaa ataatccgat tattatacaa gaagcaaatg
     2821 gtgtggcgga gaatgcagaa ggaaatatca ttgaactgaa gccttttaca gtttttgtgt
     2881 caactttcac accaaatcaa ggaacgcctg tctttgaaga tatgcgttat ttcccagaaa
     2941 agatccaaat cgttgaaaca cagtcaagtg ctcaattttc taatcatacc gctatttttt
     3001 cagcaccttc aaaaggagaa tatacgctag aagtcactta tcgttcggaa atatttgatg
     3061 gggaaaaatg gtctgctcat acagaatctg ttacccagca aaaagcgatc actgtgcgag
     3121 aaactgccga tgtgcccccg ggaaatgaca aaccagaaag agaaaatcca ggaaatgaat
     3181 caccaaatgg aaaaccaaat ggaaaacctt ctcatccgga taggacagca aaagaaagtg
     3241 aaaaaaatgg cactcaagga ctcccaaaaa cgggagaatt taataacccg ttgctagcat
     3301 tagctggagg aattttgtta atcggtgtag ttgtttatgt catgaaacag cgaaaaaaat
     3361 aagtggaatt tctcctttta tgatgtaaaa caattgactg aggaaagtaa aaatagaagg
     3421 aaatgagacc aatagatgtc tcacttcctt ctatcttttt atagatgagg ttctccttgc
     3481 tgcttttgat tggctgttct tattacttga tgcaggacag ctttttcaca atctctccac
     3541 taaacggtgt tcaatcagct gaccctcggt attagctcaa caaacggcaa aatatgagga
     3601 actatttttc cgtttttttc tctaatactc aggtcaggac gctgatttca caacctctcg
     3661 ataaacggtg ttcaaaagcc agtttctcgg tagtaagtca aatttatgca aaaatgtgga
     3721 aagccatttt cacaaaattt ttcttactac ttgaaactaa gcagcttttt cacaacctct
     3781 aatacatggt attccagaag taacttcttc gaaaaataag ccgaaatgtc acaaaaattt
     3841 gagaagcgat tttcccaaat tccttcttat ttcttgaagc tgaccacttc tggcacaacc
     3901 tcttaccaga ttcgcactct tttttctggc gctagataca tagcgtcttg ttccgtgata
     3961 ccaaatgttt catagaattc gtcaaggttt tttggttgca cgtttgctcg gagtttagca
     4021 ggggcatgga catcgatttg cagtaaaagt tgttggtatt ctttttttgc ttttgtacgc
     4081 caaatcgttg cccaattgac aaagaattcc tcgatagaaa gatctgattc cgtttttgct
     4141 gcttccaatg cacagcttag accgcctgca tcagcaatat tttccgaaac ggttaatttt
     4201 ccgtttactt ttccgtcagc aaaaggcaga ccatcgaatt cttcgatcat tgcttgtgct
     4261 ttgttttgaa attgtgtaag atcttcttct gtccaccagt tgttcaagtt gccatattcg
     4321 tcaaataaag cgccgttatt atcaaatgca tgggaaatct catgagcgat aacagctccg
     4381 attccaccat aattagcaga gcttgattgt tctagactgt aaaatggtgc ttgaaggatc
     4441 gctgccggaa agacgatcac attccgaaat ggatgataat aagcattgac cgtgtcagca
     4501 ctcatttccc attctgaacg atccactggt ttgttccatt tgctgaaacg atcttttaat
     4561 gtgagtttgc tgaaaacaag agtatttgaa agcaaagtac caccctgatc tgcaggtact
     4621 gttttgaact ggtcgaataa tgctgggatc ttatcggggt agcctacttg gatacctaag
     4681 ttatttaatt ttatgacggc tttttctttt gttgcatccc caagccagtc attttcttct
     4741 agacgttttt tataaacggc gatcattttt ttcaccattt gttctacgtc ttttttagca
     4801 gcttcgccaa aatatttttt tccgtagtaa tcgccaacta cttgatcgaa ttgtccagag
     4861 gcaaggtaat acgctgcttt tttctgaggc attgcttcgt ctgttccaga caatacgcga
     4921 gaatagattc cgctgacttg gcggaattct tctgatagat aaccactaag agaacgtact
     4981 gttttaatga tcatccagct tttgaataac ggaaaatgag cttctgtcag gatgtcattc
     5041 aaatgatcga agtacactgg atcagttacg atcactttat ctggagttgt cccaatcaaa
     5101 cccgtgacaa gttttttcaa gtccagttta tctgtgtatt taataaatgt atcaaaagat
     5161 tgcggattat acattttgct gtaatctgcg ttttcttctg cactttttac atgaggagca
     5221 atcaatttat caaattgcac tgcttgttcc gtgattgctt ctgcctgact tttttctttg
     5281 ccggcaagct ctaataactg aacagccata tcaaagaaaa cgcctattag ttgtgcaccg
     5341 ttgggatggt ctgatgcata atacgtctta tctggaagga ataaagaagg cggataagca
     5401 aagaaggcgt tcgtttgcgc attcttcata tctgcatcta catccagatt aaatggcaat
     5461 ggtaatgtat ccaacagcca ttctggaaat tgcttattca attcgtcgaa agactgcaat
     5521 gattcaactt tttcgattat aggttgaagc ggttgagcat gcaactcatt tcttcggtca
     5581 taatcgtttg ccagttgata atatgcaagg aaatgtttca ttttttctga agacactttt
     5641 tctggatggg caagcagatc gtctgtttct cccatcaaaa gttggtcgat cccgtcaact
     5701 aaatcttgga aaccgcctgt agctggttta tctgcaggga tttttgctgt tttttgccat
     5761 tcttcattga ctgcttcata gaaatcttgt ttcaatcgtt ctttgttcat tcatcgatcg
     5821 ctcctttttt gtttcgtgtg cccattatct tacaaaatga aggaattaac aaatagaaca
     5881 taaaaaattg aaaattcgaa caatcaaact gatttgtttt tttcaatcct tcacttataa
     5941 tgaaaaaaag gaggcgatcc caactgaatc aagtagtgga taaaccttta tatttcaaag
     6001 tagataaaaa aattaaaaaa ttagccagca ctcagcagct gcagtcaaga aaaagtaaat
     6061 tgcttttttt agctctggtt tttgaagatc aaagttatgt gattatcgat caatcaggac
     6121 atccggtaga atattctcca gcaaaatata cttatcaaga gggtctttct tgtaaaaaat
     6181 ggaagctgat caatgaagag ccaatcgagt tatctagatg gatcaacaga aaagaagata
     6241 ttcccgtttt gatcgaagaa aaaaggtcag gaaaggaact cgcaaattgc tgggtgggat
     6301 tgccagaaga acgttttttg aggtataaga aatgggctac cccctcaggc tatctttgtg
     6361 gtacttacgc ggcagcagtt ctccttgcct attatcaaga ctatcgtaag gggtggatgc
     6421 ttccaaatga gattcgcaag aaaaatacgg ctgattcgtt ggttttgacg aaggcattgc
     6481 gtagccagat ccaaccacta ggacttccta cgattccttt tcaggttagt acagggattt
     6541 ctagtttttt aaagaagaat ggcaatcatg agcgtgcacg agcaactctt ctaggttcat
     6601 ggcagcgagc tacaaaacgt atacgtgaag gcaaacctgt gatgattggt attttgaaag
     6661 tacttggcag tacatatggc aatcattggg tgacagcgta cgcttatttt gaaactgaaa
     6721 caggagaacg ttattacaaa gtacacgaca actggggcga ttatcataaa gtcattcctg
     6781 ccagttggag taacggaaca gtttcacttc cttaagaatt tgctgaaatt aacagaaaat
     6841 cttggaaaaa tatgttaaac tatcgaagaa tagagaagtt ttggggagga ctacatgagt
     6901 aataagtatc aggatgacac gttgaagatt tttagtttga atggcaaccg tccattagct
     6961 gaaaaaatcg cgaaagtgtt cggaacagaa ttaggtaaaa gcgtcgtgaa gcaatttagt
     7021 gatggcgaga tttccatcaa tatcgaagaa agtattcgag gggatcatgt gtatatcgtt
     7081 caatcaacga atgcacctgt caatgattac tatatggaac tactgatcat gatcgatgca
     7141 atgaagcgag caagtgcgaa aacgatcaat gtcgtattgc cttactatgg gtatgctagg
     7201 caagaccgca cggcgaaacc tcatgaaccg atcactgcga aattgatcgc taacttgatc
     7261 gaagaagcag gggcaactcg agtactgact ttagatctgc acacggttca agtacaagga
     7321 ttctttgata ttcctgtaga taatttattt acgatgccgt tgtttgctca ttattaccgt
     7381 caattaggtc tgacgggaga tgacatcgta gttgtttcgc caaaaaacag cggtgttcag
     7441 cgtgcacgta gtctttcaga atatttgaac agcacattag ccatcgtaga tcatgcagat
     7501 gatgcttcaa ctgagggtgg ttatgtgatc ggtgatgttc aaggaaagac atgtatcatg
     7561 gtagatgata tcttgaacac aggagcaacg cttgcacgag cagcaaatgt attaaaagaa
     7621 aacggcgcaa aagaagtata tgcctgtgcg tcacatggat tattgtccga tcatgcgaaa
     7681 agtattttag acaatgcacc aatcaaagat atttgtatca ctgattctgt tttcacagaa
     7741 gaaaatcgtc atccagaaaa cttaacaatc gttacatgtt cagaattaat gggtgaagcg
     7801 gtcaaacgca tccatgaaaa tacaccgatg agtccgttat tccgtctgga agaaaaagaa
     7861 ttcgaataaa caaaaaaaag agggaaagaa gttgtgacag aagtgagcag cttcaaggag
     7921 ctgcgacaag acttttgtca cagctccttt tttctatgcc catgaaacgt cctctagaca
     7981 aaaatgagct cttctttggt ttgttcgcta ttttatgcta gaatgtgcct agcaataatt
     8041 tggaagggat gaatgaagtg aaaactattt atctggatca tgcggcaact acccccatgc
     8101 atccacaagt aattgaagcg atgacggcaa tcatgcaaga cacgtttgga aatccttcaa
     8161 gcatacatgg atttggtcgc cacgcgcatg aaaaattgga aacagcaaga caaatcattg
     8221 cagacagtct gcaagcaaaa cctcacgaga tcatctttaa cagtggggga acagaagggg
     8281 ataatacagc tatcttagaa acagcgttct cgcgtcaaaa agaaggcaga catctaatca
     8341 ctacagctat cgaacatcct gctgttctta ataccatgaa atatttagag acaaaggggt
     8401 ttgacgttac atatctgcct gtagatgaaa aagggaatct gtcgatcgaa gaggtcaaaa
     8461 aagcgttacg agaagatacg atcttggtct ctgtgatgta cgggaacaat gaaatcggaa
     8521 atttgatgcc aatcaaagaa atcggtgaac ttttagcgga tcatccagct tatttccata
     8581 cagatgcggt acaagcgtac ggaaaccaaa cgatccatcc agaagaatta ggaatcgatt
     8641 tattaagtat ctctgctcat aaaatcaatg ggccaaaagg cgtcggtttc ttatataaac
     8701 gagacggagt aaatatccct gcattgcttt taggcgggga gcaggaagaa aagcggcgtg
     8761 caggtacaga aaatttagca gggatctggg gtatggcaaa agcagttgaa ctgctgtcac
     8821 ctgaagaacg tgaagcacgt aacaacaaat ataaaggatt ccagcaattg attcttgata
     8881 cattagaagc aaacgaaatc ccttatcaag taaatggtga tttaacgaat aaactccctc
     8941 atgtgttgaa tcttcgctta attggcgaag caaatgattt gctactgatg aagcttgatc
     9001 ttaatggggt cgctatttct actggttcag cttgtacagc aggaaatatc gagccttcac
     9061 acgtattaga agcaatgtat ggagaagata caccgatact aaaagaatcc atccgtatca
     9121 gctttggttt gggaaatacc gaagacgaca tccagtattt ccttgatcaa ttagttcgtg
     9181 ctgtcaaaaa ataactagtg aagtcattct tatatgaaca gatgtctgag agaacgcctt
     9241 cattttttag ggaacttaac tgaaaaacct agtaaaaatc aggataaact tttataataa
     9301 agagaaacta attttatcga ggtgaaaatc atggcatttg aaacaacagc aacggtactg
     9361 ggcgcaccaa ttagctatcg tttgcatcct gatgcaaaaa gatatacatt gcgcgataat
     9421 ggatttacag aaacaaacgg aggcaattat caattgatcc gaccattaga tgccacgccg
     9481 caaagcaaag aaggattcaa attaaaaatc actgtatcaa aagatattca aacattgaaa
     9541 atgtcgatca ctacagcaaa tggattgaaa gcagtcaata ttttcaaaga tccaaaacag
     9601 aaaatgagcc aagataaatt ttattttctg atggatggga tgattagccg tgggttattc
     9661 gaaaaagtcg aatgatctgt ggatataaaa agacaactag ttttgaaacg gcctattgtt
     9721 agatgactaa ctttgtaagg acgacgcaaa ttagttgtct tttttatttt taaatttaac
     9781 acatgttgtt atttttaata ttttgctgat ttattgtttc taagtaaaga aatttaaatt
     9841 gaaacgattg ttatttaggg aaaaaggtat tttttgaaaa aagaatcccg tataatgatt
     9901 gttgtgcaaa cgctatacaa aatgaaaaag aaaagaggga tgtttatgga aaatgaacag
     9961 tcggtcgttt taacgaattg gaagagaaat tatttgttct ttttatcggg acagtttttg
    10021 tcaggaatca ctagtatggt cgtccaatat gcgatcatct ggtatttgac aagagaaacc
    10081 ggttcggcga caattttgag ttttgctact ttactaggaa tgattcccat ggttttacta
    10141 agcccatttg taggaccgct agtggatcgc tgggataaaa aagctctttt gattgtcacg
    10201 gatattattg tagcgatttt cgcgcttatt ttagcagtag tcggaacgat ttcagaatcc
    10261 ttcccgattt ggctagtttt tgtgtctttg tttatgcgtt cggtcgcaca aacattccaa
    10321 atgccaacga tccagtcgat tatgccgaca atcgttccat cttctcacat aacaaggacg
    10381 aatggacagt taggaatggt ccaatcagcg aatttcatca ttgcgccagc tctaggtgcg
    10441 gctttgtttt cagtcgttcc tgtcaattac cttattttat tagatgtatt gggggcagtt
    10501 tttggtgtcg gcttattgat ttttgtgaag atcccaaaag tttctcctga aatattggaa
    10561 gttccgctta ctatttttaa agatgcaaaa tttgggctgc agcaattgat ggataataaa
    10621 gggttatggt acataacgat caatggtgca tttgtgatgc tgttgttcat gccagcaatc
    10681 agtctgtatc cattgatgac gctagattac tttggtggtt ccgttggaca ggcgggagca
    10741 gtggaagtag tctacgcagt cggaatgctc ttaggcggtg cactgatcag ttttatagga
    10801 acatggaaag accgaatgaa acctattatt atagcctaca tcattatggg cctgacgatc
    10861 ggtgcaagcg gattggttcc aaacgatagt caagggttct tgtactttct tatcttgaat
    10921 gcaggagcag gttgtgcaac gccatatttc aatacactgc tgatggcaat gatccagcag
    10981 agttatgaat cgaatgtttt aggtcgtgtc ttagggaact tcaactcttt gatgaacctg
    11041 gcaggtccaa ttggattatt atttgcagga ccattagctg atcgtttagg ggtagaaaaa
    11101 atgttcttgt tttccggaat cgggatttta ttatgcggaa tcgttttatt tttaacgtca
    11161 gctgcccgaa attatgataa agaattacag aaaaaactgg taaaagaaca ccatgagcaa
    11221 aaagacgaat agtatggaat ggagttgtga cagaagtctt gttacaactc catttctgat
    11281 cctaatgttc ctgtggcaat aagcctactc aaatgaaaaa tatgagtaat tatctttatt
    11341 tgtttaatac ttgatatagg gcagtttttt cacgacctat cgtacttcct ctttgcttca
    11401 tagatttctt tgatttgttg ctcagataac ggagtgccaa atggtagttt ttcctttaag
    11461 agttctcttt ccggtgcgtc tacgcctaca ttgacatcgt tctcgatagg tacgctgtaa
    11521 tgatggatat gtccatgaag attgcggata gtgtcgttag gcccgagcaa catcggataa
    11581 tgagtcaagt aatattgttg atggtcgaat ttaacgatgg cacctacatc ataaaaataa
    11641 aatttgggac ttccgtcagt aagcctagga tcattttttt ctaaataacg gaaaaaagcg
    11701 cgactgtcat ggttcccttt gatcaagtgg attgttcctt gcagttgagt gaccagttcc
    11761 aaaatttctg catttgcttt ttcatattgc ggatgcatag caaggtcgcc tagatgataa
    11821 acatggtcgg tttcttttat tactgcattc cagctagtga tcaactgttg gttcatttca
    11881 tccacatttg caaagagccg cggagcaaag tcgttttttc ctaataagcg ttcatggaaa
    11941 aagtgcatat cactgataaa gtaattcatg tatcttttgc ctcccttttt tcttagagta
    12001 aacaaaatca cttatctgag caactcataa catctaaaaa gaaaaggttg taaatgagac
    12061 gtgcagcttt aagcgataag aagcaatttt gaaaaatagt ttttcacaat ttataaaatt
    12121 attccttatt gccgaaaggc tggccctttt tatgagtatg ccaatttttt atatcgaatg
    12181 ctcaaaagat gagtgatttt ttggttgact atcatgtttg tgtactgaat aggtccagta
    12241 gaacagtatt tttacgactt gataattaag ggatgaaatt ttcagaaata tgacgtataa
    12301 tgtaaaatac tgaaaagttg cgaccttcaa ctcgtagatg tttcagaatc taattgaaat
    12361 gatggtgata tcatgacaga caacagcaaa acacgcgttg tcgtagggat gagcggcggt
    12421 gtcgactcat ctgtaacagc acttttgtta aaggaacaag gatacgacgt gatcggaata
    12481 ttcatgaaaa attgggatga cacggacgaa aacggtgtat gcacggccac ggaagattat
    12541 aaggatgtag cgaaagtagc tgctcaaatc gggattcctt attactctgt gaattttgaa
    12601 aaagaatatt gggatcgtgt atttgaatat ttcctagccg aataccgcgc aggacgtaca
    12661 cctaacccag acgtgatgtg caacaaagaa atcaaattca aagcattctt ggattatgca
    12721 atggatcttg gcgccgatta tgtagctact ggacattatg cgcaagtcac tcgcgatgaa
    12781 aacggcgtgg tccacatgct tcgtggagta gacaataata aagatcaaac ttacttcctt
    12841 agccaattat cacaagaaca gctttcaaaa acgatgttcc ctctaggcgg catggaaaaa
    12901 tcagaagtac gggcaattgc tgaacgcgca ggccttgcga ctgctaagaa aaaagattca
    12961 acgggaatct gctttattgg tgaaaagaac ttcaaacaat ttttgagcaa ctatctgcca
    13021 gcaaaaaaag gaaatatggt cactcttgat ggtgaagtca aaggacaaca tgctggcttg
    13081 atgtattata cgattggtca acgtcaagga ctagggatcg gtggcggagg agattcgcaa
    13141 gaaccctggt ttgttgtagg aaaagatcta gcgacaaaca cattatatgt ggggcaaggg
    13201 ttccatcatc ctgcattgta tgccacaagc ttggatgcaa gtgaaatcca ctttacgacg
    13261 aatgaaccaa tgccaaaaga attcaagtgt acagcgaaat tccgttatcg tcagcaagac
    13321 gttcctgtga cagttcgctt attggatgat aatcgtgcag aagtcgtatt cgacgaacct
    13381 gtacgtgcaa tcactcctgg acaagcagtt gtattttatg atggaatgga atgtctgggt
    13441 ggtggtttga tcgaccacgc atatcaagaa acaaaagttt tacaatacgt ttaagcgata
    13501 ttaaatgaat caaaacagct atggctaaca aaagaaacac cttttctttt ggatagcata
    13561 gctgtttttt tgcaataaaa ttaattttta ttcattttat acttgaaata cttgtgtaaa
    13621 aagttcataa tatccaataa tatgaataaa gttgcttttt gttaagcaag agcagttgca
    13681 aaatagaagg gaatcttttg caagtgattt gttcaatttt ataagtgagg gtgatggaaa
    13741 tggaaaagaa atcgacgggt attagcaaat ggggactggt tgctctggtt gtcagttcgt
    13801 caatcggaag cggtgtgttt gggatcacaa gtgatctggc tagttctgca gctccagggc
    13861 cagcgatcct ttcatggata atcgttggga ttggtatttt agctttggta ttatcgctga
    13921 atcatttagg agaaaagcgt ccagatctag atggtggtat tttcggttac gcggaagctt
    13981 catttggtaa attaggtggc ttcatcagtg gttggggtta ctggttgtct gcgtggctgg
    14041 gaaatgttgc ttttgcaacg atgctgatga gcgccatggg agaatttttc ccgatattca
    14101 aaggtggaca aaatgttcct tctattttat ttgcaagtat ttttatttgg ggtctgactt
    14161 tattagtaaa caatggagtt gaaggagcga gcgtcatcaa tacaatcgtg acgatctgta
    14221 aattagtgcc attattccta tttttaatat ttgtatttat cgcatttaaa gtgaatatat
    14281 tcactgctga tttttggggt aacgtatctg ataatctagt gaatggaaca gggcagcaag
    14341 gaacgatctg gttgcagatt aaaggttgtt tgatggttat gatgtgggtc tttgtaggga
    14401 tcgaaggcgc aagtgtttta gccaaccgcg cgaagaaacg ttcagaagcc cagcaagcat
    14461 cgatcattgg tctgctttgt ttattgttta tctatatcct tgcttcgatc ttgccatacg
    14521 gcgtcttatc tcaagaagag ttagcaacta tttcacaacc tgctatggca aatattttaa
    14581 aaggaatcgt gggaaattgg ggagcagcgc tgatcaatat cggcttgatt atttcgatca
    14641 ttggttcttg gttgtcttgg acgatgctcc cagcagaaac aacgatgttg atggctcgag
    14701 acggtctgtt gccgaaaggt tggggaaaaa cgaataaaaa aaatgcccca acttattcgt
    14761 tagttgttac tgcaatcttg actaatctat tcttattgac tttcttagtt actgattatg
    14821 cctatcaatt tgcctattct ttatgtacag cggcaatttt gatttgttat ctacttgtcg
    14881 ggatctatca agtccagttt tctttaaaag aaggaatcaa aaaacaagta gtgatcggtg
    14941 ggattgctgt agtttttgaa ttgatgggca tcattttagc aggattttct tatgtccttt
    15001 tatgtagtat tgcctatctt cctggttttt gcttctactg gatcgcttgt cgtgaaacca
    15061 aacatcaaat tacgggaaaa gaaaaagtaa tgattgggct gatttgtgtg gccgcactgc
    15121 tttcaatcgg gttgcttgct gtaggctgga tcaagatata agggggaaag aaacatgaaa
    15181 atcgcaaatt tcggtgtaga agaatggcta aataaatggg aaaagaaagc ggtatatgat
    15241 attgcacaaa gctcgatcga agcattgaca ttagacgaac tcgttggctt agatgggact
    15301 agcgtaagta aatttttcga aaaacgcaaa aacgaaccat tggactatgg ctggatcgaa
    15361 ggatcagatg ttttcaaaca agaagtcgct tctctttatc aaaccgtcga tccggaaaac
    15421 atcttacaaa cgaatggagc gactggtgct aatcttttag ctctatacgc gttagtggaa
    15481 gcaggagacc atgttgtttc gatgcttcct acttatcagc aattatatga catccccaaa
    15541 tctttaggtg ccgctgttga ctttgttcat ttgaaggaag aagaagattg gcagtttgat
    15601 ttagaacagc tagaagcctt agtcaaacct gaaacaaaaa tcatctgttt gaatagtgca
    15661 aacaatccta caggcacatt gctagatcgg aaaactttag aaaaaatcgc agaaattgct
    15721 cgtacagtag atgcatatgt attgatagat gaagtatatg cgcctttaac ggataaaggt
    15781 gaattcttgt cgatcgtaga tgtctatgaa aaaggtatag caaccaattc cctatccaaa
    15841 acctactcca ttccaggtat tcgtattggc tggacagcta ctggacctga gttggcagaa
    15901 gtttttcgaa agtatcgaga ctacacgatg atttgcggcg gagtcctgtc agatgatctt
    15961 gctgtacatg cattgaagaa taaagaaaaa atattggcgc gaaacaaaaa gatcattaca
    16021 gagaaccttg tgattttaaa acaatgggta gccaatgaac cgaaagttga acttgtcgct
    16081 cccaattacg tctctacttc tttcattaaa ttagccatcg aagaagatga ccagacattt
    16141 tgtatcaatt tattagaaga aacaggagta ctattagtac caggaagtgc ctttgattta
    16201 ccgaagcatg cccgactagg ttactgttgt aaaaaagaaa ccttggaaaa gggattattc
    16261 ctcttatctg agttcttgaa aaaacaggcc taaacaaaaa cactgcaagg acagtctgtg
    16321 acaactgttc aagcagtgtt tttcatttac gcttattgtc tatgagaagg agagtgccct
    16381 gaagctatgg agactcctga agctttttct tctgcagttt cttgctgatg gatctcttgt
    16441 gtattgtgtc gtacaagcaa gaagttgacc aaaacaagaa gagaagtcga aagaaagacg
    16501 ccgcgataac caaatgcact ggaaacactg gagccgatca taggccctac tacgttacca
    16561 gttgcttgga aagattggtt ataactgaag atccgtccag cagcttgatg aggcgaatat
    16621 tttgtgatca atgcttggac agcagggagc agacaagcat cagagatacc aatcaaaaaa
    16681 cgtaaggcag ctaattgcca aacattcgtg acgaatgcca ttgggatata aaccagaatc
    16741 gcaaaaccca aaccaatcgc aagtattctt tcactcccaa tcttgtcacc taagcgacca
    16801 aatcttggag cggctatcaa agtggcaatc ccaggtatcg aagcaatgat tccgctgatc
    16861 aacgtaacat tcccatgtcc atgcagcaat tggcgaatgt acagactgat gattggacta
    16921 atggaattgt tggatgcttg gatgatcatc gttgtgacga acataccgat gacgacgtgt
    16981 ggatatttca agtctttgaa aatctgtttg gcagaaacca tgttttcttt tttcactggg
    17041 acaaattttt catggacgaa aaacagactc aacaagaaga cgaaaaataa gatgatccct
    17101 gtaatgaaaa aggtagggcg atagccaaac gctgaagcag agatcccgcc aagaagcggt
    17161 ccaagtaatg ttcctgtaac agaaccagtt gctaaggttc caagaacttg accacttttt
    17221 tcttttggcg tcccagttgc gacaagggca gtggcattac tgatataacc agaaaaaatc
    17281 ccttgaagca gacgcaatgc gactaattga tacacactag tcacgcaacc catcaaagaa
    17341 atgacgattg ccattcctaa tgaagcacgc aacagcatca attttcttcc tttttggtcg
    17401 gctaattttc cccaccaagg agagataagc gtagtcacca agaaagtaga tgaaaaagtc
    17461 aatccgctcc aaaagttcaa ttgtgacgta ctataattac ctaacgtatc tatgtaaagt
    17521 gacataaaag gcatgactaa actaaatccg ataccagcca taaatgttcc aaaccataag
    17581 acaaacaagt tttgttccca agtttctctt ttcctaaata atttttcctt tattcttgca
    17641 gccaattaga ctccttcttt ctgaaaattt tcatctacag ctctttatta taaactacaa
    17701 tatgtagttt atcaatgaaa gtctcttttt tctctttctt tttcgtggta aactgaaaga
    17761 gtgaaggatt tattttatga gaggaaacat ggaaatgaaa aaaagaaatc tgtctcaaga
    17821 gaaaatcatc gactgctttc gagaactagc agaagagatg gatgttcagc aaataacctt
    17881 tcagcattta gccaaacgct tggatatcaa ggctccctcg ctgtataacc atttcaaaaa
    17941 tattcgtgat gtcaaaacag cgctaacagc gaaacttctg caggaactta atgaccagct
    18001 gcgacgggct cttgtgggaa aaagtggtca ggaagcactg cagatctatg cagaaactta
    18061 tcgatccttt gctttttcaa atcaagcagt gtatgagtta ctgatcagtg taccgcatac
    18121 caatgaagct gttttattag atggaatcca tgaaacgaat cagatcattt tgcagatatt
    18181 tgaggctttt caattaacga aagaagaaaa agttcatcga agcagggaac ttcgtagtat
    18241 gatccacggt tatctttcct tacgtttttt aggatacttt acaaaagaac caacaatcga
    18301 tccagaagac agctattttt ggatgatcaa taactttatc gctactttgc cttaaacaat
    18361 cagattcatt tgtaacaatt ttaagatgtt cattaaatga cccttttata agagaaaatt
    18421 cttgcaactt tcttgaaaag tgactaagat gagtctagaa aagctgaaag aaggagcacg
    18481 agtatgtatc aagtaattac catgttcggg gacaatgagc cttggtggtt ttttgaagac
    18541 tgggaagaag atattgaaga agaagaaaca ttcgagtctt tcgaagaagc acgacaagcg
    18601 tacgaaaaac aatggaacga aatccatcaa aattatgaat atatcaatgc aaaaagtaac
    18661 tttctcagcg ccttttggaa tgacggagat gagcgctggt gtgaagagtg tgacgatgat
    18721 ttacagcaat acaagggact tgcgttgttg aaaaatcatc agcccatcac agtagaaagc
    18781 agaaaggaat tttatgaaac aactaattct agcggaaaaa ccaagcgttg cgaaagacct
    18841 aagcaaggtg cttggtgcta atcaaaagca caaaaattat tatgaaggac ccaaggtgat
    18901 cgttacttgg gcccttggtc atttattagg attgaaaatg ccggaagatc tgaataagga
    18961 atggcagagc tggcaaatgg acacgttgcc aatgatccct aaaaaactag gaatcaaacc
    19021 acttcctaaa acaggacatc aattaaaagc aatcaagcag ctggctcagc gaaaagatgt
    19081 ctcagaagca gtcattgcga cagatgccgg aagagaaggg gaacttgttg ctcgctggat
    19141 cttagagtat gtgcatttca ataaaccagt gaagcggtta tggatctctt ctcaaacaga
    19201 taaagcaatc aaaactggat tcaagcaact aagacctgcg aaagaatatg atgcattgta
    19261 tgaatctgct cttgcccggg caaaagcgga ctggctggta ggattgaatg tgaccagagc
    19321 cttaactgtg aagtacgcgg ataatttatc agcaggccgt gtgcagacac cgacactagc
    19381 attagtgaga gaccaagaaa agaaaatcga gcagttccgt ccacaaacgt atttcacgat
    19441 cacgttgcaa gctggaaaag aacaagccaa aatgcttcaa aaaaatcaat ttgctttaaa
    19501 aacacaagaa gaagcacaaa aacttgttca attgatcagt acaagcaaag gaactgtcac
    19561 agaagtccaa gaaaaattaa aaacggaatc tgcgccattg ccttatgatt taacagagat
    19621 ccaaagagaa gccaatcaac gctatggcta ttctgcaaag aaaacattaa gtcttgtaca
    19681 aagtttgtat gagacccata agatcgttac ttatccgcgt acagacagca aatatctgac
    19741 aaatgacatg aaaagtacga tgaaagaacg attgcaagca gtcagcgact ttgctcctga
    19801 ggtcaagcag tatttgaaaa acggagccat cgtccaacag acaaaagtat tccaagacag
    19861 taaagtgacc gatcaccatg cacttttgcc aactgaaaac agagcacgtt atgaaaaatt
    19921 aagtaatgaa gagcgaaaaa tctatcaaat gattgtctct cgttttttag gactgtttgc
    19981 tcaaccccat aaagtcagcc aaacaaaagt tacggttgaa tttggtaaag aacgattcat
    20041 ttttcggcaa aatcgtgtcg tccaagcagg atggaaaggc gaaactgaaa ctgagacgga
    20101 aacagtcaaa tgggaaaaag gaatgagaat caatcccgat ttcgccatca aaaaagaact
    20161 atctgcaccg cctaaaccat tgtcagaagc aagcttgctt ggtcaaatgg aaaaatacag
    20221 tctgggaacc ccagctacgc gtgcagagat tatcgagaaa ctaatcaaat ctgaactgat
    20281 ggaacgtacc cctcaaggac tgcaagtatc tcctaaaggt aagcaattat tagtattggt
    20341 aaatccctct ttagtaacac cagatttgac agaaagctgg gaaaaagacc ttgaagctat
    20401 tgctgcagga aagaaacaag caggaacctt cttgaatgga atcgaaaaag aaacaaaacg
    20461 cttggtgaat gagatcaaat caagcaaaca agaatatcaa gatttctcga ttacccaaaa
    20521 gaaatgccca gaatgtgggg ccaatctgcg cgagaaaaac acacgtgacg gcaaaatcta
    20581 tgtctgcacc aattcagatt gcaactaccg cagaagaaaa gatccaaaag tctctaatca
    20641 tcgatgcccg caatgtcacc ggaaaatgga aatcatcgaa ggtaaaaacg gtgcttattt
    20701 ccgttgtaaa tacgatggaa cgacagaaaa attgcttgat aaaaaagagc agaagaagaa
    20761 aatgaccaaa catgaagaac gacgcttgct gaaaaaatat gcacaagcag aagaaccaga
    20821 agaaagccca ttagcagcag cactaaaagc agcaatgaag aagtaataag atatgaaaga
    20881 ggttgtga
//
LOCUS       DADQCX010000049        20803 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.049, whole genome shotgun sequence.
ACCESSION   DADQCX010000049 DADQCX010000000
VERSION     DADQCX010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.049"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            598..1287
                     /locus_tag="J8R83_001639"
     CDS             598..1287
                     /locus_tag="J8R83_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574769.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="J8R83_001640"
     CDS             1274..2482
                     /locus_tag="J8R83_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9574770.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="J8R83_001641"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="J8R83_001641"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAZ9574771.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="J8R83_001642"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="J8R83_001642"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAZ9574772.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="J8R83_001643"
     CDS             complement(6585..7280)
                     /locus_tag="J8R83_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAZ9574773.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="J8R83_001644"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="J8R83_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAZ9574774.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="J8R83_001645"
     CDS             complement(8479..8670)
                     /locus_tag="J8R83_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAZ9574775.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="J8R83_001646"
     CDS             complement(8691..9581)
                     /locus_tag="J8R83_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAZ9574776.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="J8R83_001647"
     CDS             complement(9568..10335)
                     /locus_tag="J8R83_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9574777.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="J8R83_001648"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="J8R83_001648"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAZ9574778.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="J8R83_001649"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="J8R83_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAZ9574779.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="J8R83_001650"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="J8R83_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAZ9574780.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14951..15289
                     /locus_tag="J8R83_001651"
     CDS             14951..15289
                     /locus_tag="J8R83_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574781.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="J8R83_001652"
     CDS             complement(15457..16215)
                     /locus_tag="J8R83_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAZ9574782.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="J8R83_001653"
     CDS             complement(16233..17051)
                     /locus_tag="J8R83_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAZ9574783.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="J8R83_001654"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="J8R83_001654"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAZ9574784.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="J8R83_001655"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="J8R83_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAZ9574785.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="J8R83_001656"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="J8R83_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAZ9574786.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..>20803
                     /gene="dnaN"
                     /locus_tag="J8R83_001657"
     CDS             19711..>20803
                     /gene="dnaN"
                     /locus_tag="J8R83_001657"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAZ9574787.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGV"
BASE COUNT         5933 a         4245 c         3821 g         6804 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtgt attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttc
//
LOCUS       DADQCX010000050        20400 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.050, whole genome shotgun sequence.
ACCESSION   DADQCX010000050 DADQCX010000000
VERSION     DADQCX010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.050"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            134..409
                     /locus_tag="J8R83_001658"
     CDS             134..409
                     /locus_tag="J8R83_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAZ9574788.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            415..1182
                     /locus_tag="J8R83_001659"
     CDS             415..1182
                     /locus_tag="J8R83_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAZ9574789.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            1350..3179
                     /gene="typA"
                     /locus_tag="J8R83_001660"
     CDS             1350..3179
                     /gene="typA"
                     /locus_tag="J8R83_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAZ9574790.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            3439..5211
                     /gene="recQ"
                     /locus_tag="J8R83_001661"
     CDS             3439..5211
                     /gene="recQ"
                     /locus_tag="J8R83_001661"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAZ9574791.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLRKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            5325..5627
                     /locus_tag="J8R83_001662"
     CDS             5325..5627
                     /locus_tag="J8R83_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAZ9574792.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            5630..6793
                     /locus_tag="J8R83_001663"
     CDS             5630..6793
                     /locus_tag="J8R83_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAZ9574793.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            6819..10247
                     /locus_tag="J8R83_001664"
     CDS             6819..10247
                     /locus_tag="J8R83_001664"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAZ9574794.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            10268..11392
                     /locus_tag="J8R83_001665"
     CDS             10268..11392
                     /locus_tag="J8R83_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574795.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            11382..11819
                     /locus_tag="J8R83_001666"
     CDS             11382..11819
                     /locus_tag="J8R83_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAZ9574796.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            11803..12141
                     /locus_tag="J8R83_001667"
     CDS             11803..12141
                     /locus_tag="J8R83_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAZ9574797.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            12260..12820
                     /gene="rsmD"
                     /locus_tag="J8R83_001668"
     CDS             12260..12820
                     /gene="rsmD"
                     /locus_tag="J8R83_001668"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAZ9574798.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            12817..13308
                     /gene="coaD"
                     /locus_tag="J8R83_001669"
     CDS             12817..13308
                     /gene="coaD"
                     /locus_tag="J8R83_001669"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAZ9574799.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            13298..14341
                     /locus_tag="J8R83_001670"
     CDS             13298..14341
                     /locus_tag="J8R83_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAZ9574800.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            14500..15228
                     /locus_tag="J8R83_001671"
     CDS             14500..15228
                     /locus_tag="J8R83_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAZ9574801.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            15344..15589
                     /locus_tag="J8R83_001672"
     CDS             15344..15589
                     /locus_tag="J8R83_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9574802.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            15586..15804
                     /locus_tag="J8R83_001673"
     CDS             15586..15804
                     /locus_tag="J8R83_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAZ9574803.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            15940..16479
                     /locus_tag="J8R83_001674"
     CDS             15940..16479
                     /locus_tag="J8R83_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAZ9574804.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            16472..18745
                     /locus_tag="J8R83_001675"
     CDS             16472..18745
                     /locus_tag="J8R83_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAZ9574805.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            18783..19829
                     /gene="holA"
                     /locus_tag="J8R83_001676"
     CDS             18783..19829
                     /gene="holA"
                     /locus_tag="J8R83_001676"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAZ9574806.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(19918..20172)
                     /locus_tag="J8R83_001677"
     CDS             complement(19918..20172)
                     /locus_tag="J8R83_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAZ9574807.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
BASE COUNT         6837 a         3431 c         4357 g         5775 t
ORIGIN      
        1 aaaaatcagt tgcgttttgt tttttagaat tatcaataat attattatgt aaacttaaaa
       61 atatgacaac ttcttggttt attaccactt cctatgctac actgaagagg aatatgaaat
      121 aggagagttg aagatgcaag aatatcagta tccacttgat ttagattgga caacagacga
      181 aatggtcatt gtaatgaaga tgtgggaaga tctggaacgt gcgaatgaaa aagggataaa
      241 caatgaagct tttttgaaga cttatcagca gtttaaaact gttgtcaaat ccattggtga
      301 ggaaaaacga ttgggacggg aatttgaaaa agcttccggt tattctttat atcgtacagt
      361 gcagcaagca aaaaaaaatc caaacaaaac tttgagaatg aacgggtgag ataaatggaa
      421 cagatgattg atcatatcaa gtcctggctt gaagaagctg gtgagaaaat caaatcttct
      481 caacaaacat taacaatctc gcaaaaatca aatcgaacgg atctagtaac aaatgtcgat
      541 cgaaacatcc agaattttct aatcgaaaaa atccattcct ttgatccaga ggcgaaaata
      601 ttggcagaag aagaagggtg taatcaatta tcggatctcg atggaagagt ctttatcatc
      661 gatcctattg atggcacctt gaattttgtg attgaagggg aaaatttttg tattatgctc
      721 gctgtttatg aatccggcgt tggaaagctt ggtttcattt atgacgtgat gagaaatgaa
      781 cttttttggg gtggaaaagg aataggcgtg tataaaaatg atgagccatt gcctagacca
      841 gcaaataaat ccttatcgga aggcttactt ggtgtgaata gttatctttt cggtcataat
      901 aaatatggaa tccgagaaat tgcggaaagc agcatgggga cacgtatgta cggatgcgct
      961 ggtcttgaac tagtggcaat cttgaaagga aaccacattg cttatatttc aaaccttagc
     1021 ccttgggatt atgcagcggg aaatgtctta ttggaagagt ttggtatggt aacaagcggt
     1081 ctttttggta ctcctttgac atttgaaaaa agggaatact atttagcagg gacttcttgt
     1141 gcatatgcag aaatcgcaga ccttttgaaa aaagaaggct gaaaaaaagg tagaaatcat
     1201 tcacaaaaat gataaaaacg agcaaaagat taattttctc gaaaaaatga aaacatttta
     1261 ctatatttca tgaaaaaagt ctgctataat tagcagtcga gtaaaatttg ccctgtcata
     1321 aagaaccaat aaaaaaggag ttagttacat tgaattatag aaacgatatc cgtaacgtcg
     1381 caattattgc ccacgttgac cacggaaaaa caacattagt tgatgaacta ttaaaacaat
     1441 cagatacatt agacgcacat acgcaattgc aagaacgtgc gatggactca aatgcgctag
     1501 aaaaagaacg tggtatcacg attttagcca aaaacacagc tgtagactat aaaggtattc
     1561 gcgtaaacat catggatact ccaggacacg cggacttcgg tggcgaagta gaacggatca
     1621 tgaaaatggt tgacggcgtt gtgttggtcg tagatgcgta tgaaggaaca atgcctcaaa
     1681 cacgttttgt attgaaaaaa gcactggaac aacatatcac accaatcgtt gtcgtaaaca
     1741 agattgacaa accttctgct cgtcctgagc atgtcgtaga tgaagttctt gaactattca
     1801 tcgaattagg agcagatgat gatcagttag actttcctgt gatttatgca tctgcactaa
     1861 atggtacgtc aagcttgtca gatgatccag cagatcaaga accaaccatg gcacctattt
     1921 ttgatacaat tattgaaaaa atccctgctc ctgtcgataa cagcgacgaa ccattacaat
     1981 tccaagtttc attacttgac tacaacgatt atgtaggtcg tatcggaatc ggacgtgtat
     2041 ttagaggaac aatcaaagta ggagaccaag tagcattaat taaattagac ggaacagtta
     2101 agaaattccg tgtaacgaaa ttatttggtt tctttggact aaaacgtcta gagattcaag
     2161 aagcaaaagc tggagacttg attgctgtct caggtatgga agatatcttt gtcggtgaaa
     2221 cagttactcc tgtggatcat caagatgcgt tacctatcct tcacattgac gaaccaacat
     2281 tgcaaatgac tttcttagtt aataattcac catttgccgg tcgagaaggt aaattcgtaa
     2341 ccgctcgtaa gattgaagaa cgtttgatgg cagaacttca aacagatgta tccttacgag
     2401 ttgaaccaac aaactctcca gatgcatgga cagtttctgg tcgtggagaa ttgcatttgt
     2461 ctatcttgat tgaaaacatg cgccgtgagg gatacgaatt gcaagtatct cgtccagaag
     2521 ttattgaaaa agaaatcgac ggtgtaaaat gcgaaccgtt tgaacgcgtg caaatcgata
     2581 caccagaaga atatatgggt agtgttatcg agtccttgag cttacgtaaa ggtgaaatgc
     2641 aagatatggt ccatacagga aacggacaaa tccgtttgac attcttaaca cctgcccgcg
     2701 gtttgattgg ttattcaact gaattccttt caatgacacg tggttacgga atcatgaacc
     2761 atacttttga ccaatatctg ccaatgcttc ctggtcaaat tggcggacgt caccaagggg
     2821 cgcttgtttc gatcgataca ggaaaagcaa cgacttattc tatcatgagt atcgaagaac
     2881 gcggtacagt cttcgtagaa ccaggtacag aagtatatga aggaatgatt atcggggaaa
     2941 acagccgtga taatgatttg actgtcaaca tcacgaaagc aaaacaaatg acaaacgtac
     3001 ggtctgctac taaagaccaa acatctgtca tcaaaaaacc aaaacaattg acgttggaag
     3061 aatctttgga attcttgaat gatgatgaat attgcgaagt aacaccagaa agcattcgct
     3121 tgagaaaaca aattttagag aaaaatgctc gtgaaaaagc atctaaaaag aaaaaataat
     3181 ctgtaaaagg atgaagagag aaaccagctt gttataaaaa atagctggtt tctttttttg
     3241 tccaactctt ttctgtggag aagtcatctt tgtcaatgga cataaattca gaaaatacgc
     3301 cgaaagacgt ttaaaagact tttaaaaact tatttctaga gagtttttgt ttcataataa
     3361 gataatgttt cacgaaagga gatcaacttg tccttcgaag aaaatcgaag taaaatggca
     3421 agagaaagga gcgggaagat gaacgactta ttaaaacaat actttggcta tgatgagttt
     3481 agacctggtc aaaaagaaat tatccagaaa gtcattgatc aggaaaatgt attaggaatc
     3541 atgcctaccg gaagtgggaa atcaatctgt taccagcttc cagctttact attagatggg
     3601 cttactgtgg ttgtgtcccc tttaatctct ttgatgaagg atcaggtgga cgcggcgaat
     3661 caattaggta tacccgccac ttttatcaat agctcgttag atggttacga aacagctaga
     3721 cgcttccaag aaatcgatag acagcagtac cgtttacttt atatcgctcc tgaacgtttt
     3781 atcatgccgg attttatcca agcaatgaag cgatggaacg tccgtatgat cgctattgac
     3841 gaggcacatt gtatctctca gtgggggcat gatttccgcc caagttattt acagatggcg
     3901 aaccagctag atcaactgcc aaatcgtcct gtaattgttg ctttgacagc tacagcgact
     3961 gtgcaagtag ctgctgacat aaaaagactt ttaaaaattc cagaaaacaa ccatattcag
     4021 actggttttg aacgagaaaa tctacgattt caagtaatta aagatcaaaa aaaagaacaa
     4081 tatctaatcg aatatttaaa gatcaacaaa aatcaatctg gtatcattta tgcagcaacg
     4141 agaaaagaag tagaccgtct ctatcatttg cttagaaaat tcgatttttc cgtgggtaga
     4201 tatcatggtg gtctaaatga gaatgagcga acagaaatgc aagaagcctt tttatacgat
     4261 cgcttgcagc tgattgtagc gacaaatgca tttggtatgg gtataaataa aagcaatgtc
     4321 cgttttgtta tccattatca aattcctggc tctctagaag catactatca ggaagctggt
     4381 cgggcgggaa gagatggtct ttccagtgaa gccatcctgc ttttctctcc tcaagatatc
     4441 caagtccaaa agttttttat ccagcagtcc caaagagaag aagggcaaaa gcaaaaagaa
     4501 tatgaaaaat taaaagcgat gacagaatac gtgtatattg agtcctgtct tcagcaatac
     4561 atcctaaact attttggcga gacaagcagt ccgtgcaacc gttgtggtaa ctgtttagat
     4621 gacagagaaa tagtagaagt aacgacagaa gcacagatgg ttctttcttg cttaaaacgt
     4681 atgggtgaga actatggtaa acaaatgctg atgaaagtct tagcaggatc gaaagaacaa
     4741 aagctgcaag ctttaggttt tggacattta tctacctatg gactgatgaa aaaccaatcg
     4801 caaaaagaaa cgatgcagtt aattgaatat ttgatatcga atggctatct tctgaccatc
     4861 aatggtgagt atcctgtttt gaaagtaaca gaaagaggga tacaagtatt gaaaggacaa
     4921 gaatctgttt atcgaaagga acccaagaaa gtccagcagc tatcggatga agaaaccgat
     4981 acactatttg aagtgctgcg ggaactgcga acggatctag catcagaagc aggcgttccc
     5041 ccgtatgtcg tattttcaga ttccacattg aaagaaatga gccgaatacg tccatcaagc
     5101 agattggaga tgcttcagat aaaaggagtt ggccaaagca agcttgataa atatggcgaa
     5161 gcctttttat ctcggataaa aaatgcggac tctaacgttc tggataagta gaaagaacga
     5221 atacgtaaaa atgaataaaa acaactggtt aaatctgttt tttttgctcc ttatgaaaat
     5281 caaatatgtt ataattaagg aattagaatg ggaggtaagc acagatggat tctttgtcga
     5341 aaaaacttgc gatccaagta ttaaatgatg aagcagaacg gatcaaacga ttaatccgaa
     5401 atcaaaacaa cagtctctgt atctcacaat gcaaagcctt cgaagaagtg gtagatacac
     5461 agatgtacgg cttttcccgg caagtcggtt ttgctgtccg tataggagta atcggaaaga
     5521 acgagggcca gctgatgtta agtgagctag aacgagaatt gaatcagtta tatagtgagg
     5581 tttaccaaga aatttatgat aaaaaagaag ttggcaagga ggaatagact tgcctaagaa
     5641 agtgaaaaaa aggcatctat tagactatag catcttgatt ccctatttaa ttttatgtgt
     5701 attgggattg atcatggtat atagttctac gtcgtatcta ttattagaaa acggacaaaa
     5761 tccgtccgca tcagtcatta accagagtat tttttgggtg cttagcttga ttgctatcgc
     5821 actactttat aaaatgaaaa cagatgtttt gaaaaaccag cgtttgatca tggcagccat
     5881 cgcagttttg acgattttgc tgctgattgt tgtgtttttt ggtaaggaga tcaatggggc
     5941 gaaaggttgg ctgcaaattg caggattctc gatccaacct gccgaatacc taaaaatcat
     6001 ttctatctgg tacctgtctc tgactttatc taaaagacaa aacagtgtac aaaaagattt
     6061 tcttgggact gtgaaacgtc cacttgcaat ggttatcgga cttactgcat tagtcgctat
     6121 tcttcccgat tttggtaatg cggcagttat ctttttgatt attttggttc tgcttttagc
     6181 cagcggagtc aattatgtgt atactttgat tgtaggagta ggaggctttt gtctaagtac
     6241 ttttacgatc tggctgatca atatcacaaa cggaaagatc ttacccggac gtttacagta
     6301 tatctataat cgatttgcta tttaccaaaa tcctttctca gacgaattaa ataaagggca
     6361 tcaactagtc aacggctact atgccatgtt caacggagga ctatttggca ggggattagg
     6421 taacagtatc cagaaaaaag gatttttaca agaagcacaa accgatttta tttatgcaat
     6481 cgtagtggaa gaactgggag tgattatggg gattttgata ttagcgttgc tattctttat
     6541 gattgtgcgc attgtccttg taggtatccg ttcaaaagat ccgttcaatt cgcttttgtg
     6601 cattgggatc ggcgcaatgt ttttgatcca agtatttgtc aatcttggag ggattactgg
     6661 cgttattcct ttgacaggga tcacgttccc atttttaagt caaggaggct ccagtttgct
     6721 gatgctttcg atttgtgtcg gctttgtcct caacatcagt gcggatgaaa aacgcaagag
     6781 cttaggttta taataaaaaa agatgtagga gtggttcgat gaaaaaagtt ttagttgcta
     6841 acaggggtga aatcgctgta cgtgtatttc gtgcttgtac agaattagga attaaaactg
     6901 ttggaatcta tgcagaagaa gatgaatatt ccgtacaccg tttcaaagcg gatgaagcat
     6961 atttagtagg acaaggaaaa aaaccgattg atgcgtatct agatattgaa gggatcattt
     7021 ctatcgcgaa agaatgcgga gctgacgcta ttcatccggg ttacggtctt ttgtcggaaa
     7081 acttgaattt tgcgcaacgg tgcgaagaag aaggcatcat ttttgttgga cccaaactgc
     7141 atcatttaga tatttttgga gataaaatca aagcaaaagc tgcagctatc gaagcgggga
     7201 ttgcttcgat tccaggcaca gatggaccaa tcgcttctat agacgatgcc ttggagtttg
     7261 cgaaacaata cggttatccg attatgatca aggcagctct aggcggcggc ggacgcggca
     7321 tgcgtgtagc tcacgatgaa aagagtgcaa gagagggcta cgaacgtgcg aaaagcgaag
     7381 caaaagcagc ctttggtagt gatgaagtgt atgttgaaaa atacatcgct aatcctaagc
     7441 atatcgaagt acagattctc ggggatacgc atggaaacgt catccatctt tttgaaagag
     7501 attgttctgt tcagcgccgt caccaaaaag tagtagaagt agcgccttgt gtctctatga
     7561 atgaacagca acgtcaaaaa atctgccagg cagctgtcca attgatgaaa tatgtcgggt
     7621 atgtcaacgc aggtacagta gaatttcttg ttgaaggaga tgatttttac tttatcgaag
     7681 tcaaccctcg cgtccaagtg gaacatacga tcacagaaat gattacagat attgatatcg
     7741 taacaacgca actgttgatt gctcaaggtt tggatctgca taaagaaatc ggattgcctc
     7801 agcaagaagg aattaaatta aatggttcag ccattcaatg ccgaatcact acagaagacc
     7861 cgttgaataa ctttttacca gacacaggga aaatcgatac gtatcgttca cctggtggtt
     7921 ttggcgtacg tctggatgtc ggaaatgctt acgcgggcta tgtagtgaca ccgtattttg
     7981 attcattgct agtaaaagta tgtacgcatg gtgctacctt tgaaacagcc attcagaaaa
     8041 tggaacgttg cttgaaagaa tttagaatcc gtggagtgaa aacaaacatt ccatttatgc
     8101 tcaatgtcat cacacatcct gaattccaat caggaaatgc aaaaacaacc ttcattgata
     8161 gtacagcaac attatttgaa tttcctcgac tacgagaccg cggaaacaaa acgatgaaat
     8221 atatcggtga aattactgtg aatggttttc caggtatcga aagtggcgaa aaaccatttt
     8281 atgaagaacc acgtatgcct aaagatctaa tcacaagaac tgattacgta acggctaaga
     8341 atgtattaga tgcgaagggt gccgatgctt tggtcgaatg gatcaaagga caggaaaatt
     8401 tgttgttgac ggatacgaca tttagagacg cccatcaaag tctgctagca actcgtgttc
     8461 ggacaaagga tttcaagcag attgcacgtt tgactggaga aggtcttcct gaactctttt
     8521 caagtgagat gtggggggga gcaacatttg atgtggctta ccgctttttg aatgaagatc
     8581 cttggcaacg gttgagaaaa attcgttctt taatgcctaa tacgttgctg caaatgcttt
     8641 tcagaggttc aaatgccgtt gggtattcta attatcctga caatgtattg gtggaatttg
     8701 tcaaagaagc agcagcgcaa ggaatcgatg tatttcgaat ctttgatagt ttgaactgga
     8761 ctccacaaat ggaaaaaagt atccaagctg tacgggatac tggtaaaatc gcagaggcag
     8821 ctatttgcta tactggcgat atcaacgatc caagtcgggc aaaatacaat gttcagtatt
     8881 ataaagacat ggcaaaggaa ctagaacaac tgggtgcgca tatcattgca atcaaagata
     8941 tggctgggct gcttaaaccg caggcagctt atcgtttgat tagtgaattg aaagaaacga
     9001 cagatctgcc aatccatctg catactcatg ataccagcgg gaatggaatc atcacttatt
     9061 ctgctgcttc aaaagcagga gtagacatcg ttgacgtggc aatgagtgca atgagtggga
     9121 atactagtca gcctagcatg agcagcttgt attatgcact ggtcaatggt ccacggctgc
     9181 cagaaatcac gattgaaaat gcacagaaat taaaccatta ttgggaagat gtgcgcatgt
     9241 attacaaacc gtttgaaaac ggcttgaatg ctcctgaaac agaagtatat atgcatgaaa
     9301 tgccaggagg acagtattcg aatctacagc aacaggcaaa agctgtcgga ttaggtcatc
     9361 gctgggatga aatcaaacaa atgtatcata ctgtcaactt gatgtttggc gatatcgtta
     9421 aagtaactcc atcatctaaa gtagttggag atatggcact atttatggtc caaaatgatc
     9481 ttacagaaga agatatttat gaaaaaggcg aaacactaag tttccctgaa tctgttgtga
     9541 ctttcttcca aggagaacta gggcaacccg ttggcggatt tcctaaaaaa ttgcaaaaga
     9601 ttattcttaa aggcagacct gcattgaatg aacgtccagg tcttttggct gaatcagtcg
     9661 acttcaacga agtaaaaaaa gaattggcag aaaaaattgg ctatgaacca aaacaagacg
     9721 aagtattaag ctatttgatg tatccgcaag tctttttgga ctatcaaaaa gcatataatc
     9781 aatttggcga tgttacatta ctggacacac caacattttt ccaaggtata cgtttgggtg
     9841 aaacaatcaa tgtacaaatc gaacgcggaa aaacgcttat cattcgttta gatgaaatcg
     9901 gagaacccga tatcgaaggg aatcgcgtac tgttcttcaa tttgaatgga caaagacgtg
     9961 aaatcactat caaagataat tcgatcatca gtacggtcca aacccgattg aaagctgaac
    10021 cgacaaaccg agaacaaatt ggagcaacga tgtctggttc tgttttggat gtattagtga
    10081 aaaaaggcga taacgttaaa aaaggtgata cgttgatgat tactgaagcg atgaaaatgg
    10141 aaacggccat cgaagcacgt tttgacggag aagtcgcaca tgtatatgtg tcttcaggag
    10201 acactatttc gtctggtgac cttttgattg aagtgactga gaaataataa gcgaaaggtg
    10261 gggaaacatg aaaagactgg gtttgttttg gctgattctg ctattagtta ttgtggcatt
    10321 ctacatggaa ccagtcttgt ttccgccaaa acttgaagtg aaggaaaact ctgatcaaca
    10381 aatatcaaac caaatgacaa cgtggaaata ccaggagctt aaagcaactg gtttttctac
    10441 ttatatcgga aaaccgatcg atcagctgga aaaggatttt ggccaagcct atgatcgatt
    10501 aactagcgga tttggttttg aaacaagata ttatgaaaat aaagctagtc atctcacatt
    10561 tgaagcgaac atccaagaca gcagagtcac aactgttaaa gtactgcaaa cagggcctgc
    10621 tgatatcgcg ccgttttatt tagggatgac gatgcaagat cttacgaaaa tcactactat
    10681 ctatactaat ttcacttttg agtaccatga tacagaagtt ggaatcgaac taatggaaga
    10741 ggatatgaat tatcgtccgc taattgcttt tgataacgac acttttgcta ttttattttt
    10801 tgatcaaaca acaaacggcc tattttcagt tgtgtattta gataaagata gtcttttgaa
    10861 actattgcca tatcaagtgt ttggtgaagg ccttccacat tatcaagcag ataaatcggc
    10921 tgattgggaa tcaatcaatc gcgttaaaga acgaaaaagt acgactttat taaatatgct
    10981 tagaagagaa gacgaacttc ccatatacaa tcaaacactt gcctttcaaa accacagtca
    11041 gctgctacta catgattttt tgacaaggcc tgaggaaata ttgtcagagg aacgtatggc
    11101 tgattggcaa aaatcgctag gcagtgctca aacgacagtg aaattctcac tgacgaatga
    11161 tgaattggag aagttaatca gtaaacaaaa attagaaaat actagtgggc tatttattca
    11221 tccggcgatt gacgctactt tttcgttttt atattggtac agcgatcctt acaaccatga
    11281 ccgtttcatg gacccgggaa cggattctgt aggcattgct ttttctaaag aaaatatgtt
    11341 agtcttattg caagaagaaa acggagaaag tagtgatagc agtgatcgtt aacgaagagc
    11401 tgtttcaact ggaggatcaa tgcctccaag tcgctgaaat gataaaaaag agtaaaacga
    11461 tggcttctta tcttgaacat aaacagtcaa tggaagaatc tgcaaaagtt tgccagttga
    11521 aagaagcgtt cttgtctaag aaagaagcat ttgaaaatgt agcggcatat ggtgagtatg
    11581 cacctgatta tcgtgaaaaa aaacgagctg ttcgaaaagc aaaaagacag cttgatatgg
    11641 atgagcatgt tgcagctttc cgatatagtg aaacacagct gcaaagtctg ttggatcaaa
    11701 ttgtccaagt acttgccgaa gaagtttcta atgaaatcaa agtagatgca ggtagcccgt
    11761 tttttgaaac gaaaaaacac tttggatgcg gaggtaattg tcatgcaatt agacaatagt
    11821 gaatttgaaa taacaaaacg acgcgggctg atcgtatggg tctacagctt aaaacaatta
    11881 aagaatctga aaaagttcgg cttgttgcat tatgtctcaa gaagaatgaa atatgtcgtg
    11941 ctttacttaa atgaagagac attggaagaa acagaagaac gaatccgtaa attacatttt
    12001 gttcgaaacg tagaacgttc ttaccgaccg gatatcgaaa tgaattttgc cgaaaaaata
    12061 ggaaacaaaa cagtattaaa agacgaaggt ttcgaaattg aagagctaaa tacagaaatc
    12121 cgattagctg aacatcttta aaaatctctt atgagcagtt tttaaataaa aaataacttg
    12181 gataacgatc gatttttgat cattgtccaa gtattttttt ggtatactag taccagtacc
    12241 atttctaagg agtgagtaga tgcggataat atcaggaaat tatggcgggc gccgtttaaa
    12301 aagtttagca ggggcgaaca ccagaccaac tacagataaa gtaaaagaat ccatattcaa
    12361 tatgattgga ccatattttg atggagagac agtattggat ctgtttgcag gaagcggtgg
    12421 tttagctatc gaagcagtat ctagaggctg cagtcatgcg gtatgcgtag acaaaaatta
    12481 ccaagcgcta aaaatcatca aagaaaacat cgaaattacg aaagaaccag agaaatttac
    12541 cacaataaaa cttgatgcgg acaaagcaat cgaacggcta gcagcggaga aacaacaatt
    12601 cgactacttg tttcttgatc cgccatatgc aaaacaaaaa ataatcgatc aaatccataa
    12661 aatggaagaa ctgggacttt tttctaaaac cgcagttatc gtatgcgaaa cggataaaac
    12721 agtcgaattg ccagaaactg tggctggatt ccatcaaata agaaaacaga tttatggcat
    12781 aacggccgta actatctata gaaaagaggg aaatcaatga aacgtgcatt attcccagga
    12841 agttttgatc cttttacaaa aggtcactta gatacggtgg aacgtgcggc taaattattc
    12901 gatgaggtag taattggtgt ttttatcaat acttcaaaga aaagtttgtt tcccccagaa
    12961 gaaagaatga cattgatcac aaaagctgtt tctcatcttc ctaatgtaaa agtcatgcat
    13021 caagaaaatc aattgacggt agaaacagca aaagagattg gtgcagatgc gttgatcaga
    13081 ggcatacgaa gtatcaaaga ctttgaatat gaacgagaga ttgctcagat gaatcatcat
    13141 ctatatgatg aattggaaac tgtcttctta ttagcaaaac cagaatatag tcacgtgagt
    13201 tccagtattt taaaagaagt actgcacttt ggcggagatg tgagcagcta cttaccgcca
    13261 gtgatcaacg aagctttagc tggaaagcgt gaatcaaatg aaagctaaac aatggttgaa
    13321 aacagtactg attatcatat ttggaatgtt gatcattgga tttgtagtag ttcccttgcc
    13381 gtattatgta gaatcaccgg gagccacgat cgatctgaaa gaactaatta cggtcaatga
    13441 taaggaagat aaaggttctg ggtctttctc tcttacctct gttggtatca ggcaagctac
    13501 aggtttctta gctttaaaag ctaaaatgac cccttttgaa gaattgatca gtgaagaaga
    13561 attgactggt ggggcgacaa atgaagaata taatcaaatg caacagtatt atatggattc
    13621 ttcccaaaat gcagcaatcg aacaagcgtt aaaacttgca gacaagcctt ataaaatgga
    13681 attcaaaggc gtatatgtca tgagtgtaga gaaaacatcg aatttctttg gcaagctttc
    13741 agttggagat acagtaacaa aagtagacgg gaaaagcttt caaagtacag aagcatttat
    13801 ggattatgta aaaagccaaa aagttggaca aacaatcgaa atcagttatt tgcataatgg
    13861 tgaagaaaaa acagcttctg gtgatctgat cgagttacca acagataaaa aggcaggaat
    13921 aggtatcacg cttactgacc ataccgagat cgaatcagat acagatgttc gtattaattc
    13981 tggctctatc ggtgggccat cagcgggatt gatgttcact ttagaaatct atgaacaagt
    14041 cactggtaaa aacttgcgac atggtaagca aattgcagga actggaacga tcaacagtga
    14101 aggagaagtt ggccgaatcg gaggaatcga taaaaaagtg gcaagtgcgg ataaagctgg
    14161 cgtagagatt ttctttgcac cagatgatac gatttcagac gatgttaaga aagaatatcc
    14221 tgaaataaaa accaactacg aagaagcaaa agctgccgct aaaaaattga attcctcaat
    14281 gaaaatcgta ccagtaaaaa cagtacaaga agcgcttgac tatctagaga aaatgaaatg
    14341 aaactaaata attaaagagg ggttgtgaca cgagttctgt cacaacccct ctttttcgtc
    14401 aaaaatcttc acgataaaaa taaaaacaaa agaaaaaatt gacgtaatta gatgttgaag
    14461 ggacgatttt gccagagctc actgtttctt caattttaaa tgaaaggagt aatgaatgat
    14521 ttttactggt cattctttga aaaaagaaca atgatagaaa aaatcagcaa gaaaatacta
    14581 gcttcaccca aattgatcat ttggatgtct atgatagttc ttatcttttg tatcgcaagt
    14641 ggttttttat tatcaaattt gctattttat agagaaacag aagagactgc tgcaaaagaa
    14701 atactttctt cgtttagttc cagtggagaa gatccatcag ctgaaggaaa cgatgtagaa
    14761 gaggatgctc gtccaaaggt catgtacacc gatatcaaag gaagtgtgaa ggagcctggt
    14821 atctattcct tttcttcaga agaacgggtc tatgatgtac taaagcgtgc aggtggatta
    14881 ttagaagaag cggatagcga tcgaatcaac ttttctgcga agatagaaga tcagcaagtc
    14941 ctatatatcc ctgctgtagg tgaagagctg ccagaacatc ttgatcagtt ggcatcctcg
    15001 gaaggaaaac agcctacagc agattccgag cctcccaaaa taaatatcaa tacagccact
    15061 ccatcagaac ttcagcagat tcctgggatc ggatcagtca aagcgcaaga aatcattcga
    15121 tttagagaag aaaacggatc cttccagaaa gtggaagacc tgcaggagat ttctggtatc
    15181 ggtgaaaaga cagttgaaaa actaaaaaac ttcgttacaa ttaaatagaa tgattcaaaa
    15241 tcgactggca cgagcaataa atggacgcta atggatacta agaataatcc aattctaaga
    15301 gcttggcagg acgaggaggt agtatttttg gataggaaat agcttgattg ttcgcaaaga
    15361 aacattaaaa aaaccaatgc tgaatgtcta tctccaaaat aaaatatctg ggattcatat
    15421 tatgaatacg gctgtcagcg gcaataacag tcaagctcta cgagaacgct ttgccaaaga
    15481 tgtacttagc tatacagcag ataaagtatt tattctcatt gggacgaatg atctagcaga
    15541 gcataaacaa ctttctaaag aaacgtacca aaaaatctgc agtggatgat agttcagctg
    15601 aaaaaagact atagttctga tcatgctttc tttatcacgc caccagcagt cgatgagaca
    15661 aaacaaaaat atcggaataa caagttgatc aaagaatata tctctgttct cacagaagta
    15721 gcaaaacgcc atgattgtga agtatcgatt tttatacgga atttcttgaa caaatggatt
    15781 cgaagaattt ttataatggg ctaatggatg acggacttca tttcggcagt gaagggtagg
    15841 atcttttgtc agacaggatg attcgttata tttaaagaat attttgttta agcaatgagt
    15901 actttttaat caacttgaaa aaacggagga atataaaaca tgttagaaaa atcttcaaaa
    15961 gcatgcgata cgaataaaga aaaagttact gataagtcac ataatgaacg cattccttgg
    16021 gaccagtact ttatggctca ggcagtactg ttatctttac gtagtacgtg tacacgttta
    16081 gaagtaggag cgacactcgt tcgagaaaaa aggatcattg ctggcggcta taatggagca
    16141 gtcagtggag atgtccactg catagatgaa gggtgttacg tcgtggatgg acactgcttg
    16201 cgaacgatcc atgcagagat gaatgcactc ctacagtgtg caaaacttgg tatcccgacg
    16261 gaaggttcag aaatctatgt cacacatttt ccatgtttgg cctgtacaaa ggctttgttg
    16321 caagctggtg tgaaagggat caattatctc catgactatc gaaatgatcc ttatgcccaa
    16381 gcgttgatcg aacaattagg tgtatctgta caccaagttg ctttagactc acagcatttt
    16441 tcaaaacttc aaaatgaatt aacaggaaaa catgtctagc gttttagaaa ggcatgttcg
    16501 aaatcggttg atttttccgg caattacgtc gatgattatc tgtttgttgt attacactga
    16561 caattggggt tatcgtttgc ttcttgccgg aattttttta tggttttcgc taaaagaagg
    16621 acgttttatc gcgtacttgt gtattttgtg tagcataacg gtatccattt cttataggct
    16681 acaagagtat tcatttttag aggaaaaaac aacatctgcg caaattactg tatttacaga
    16741 tacgattcgt gcaaatggta attttttgac aatggaagga aggttatcag agaataaaca
    16801 aaagctccag ctttcttatc aagtaaacac agaagcagaa ttgaaaacat ggcttaactt
    16861 ccgaggaaag ggaatagaat tgactgctga aggcgagttc atctctccag caaaaaagcg
    16921 gaatctttat aattttgacc aagaagctta cttcaggaac catagaattt ctggacggtt
    16981 ccaaattcaa aagattgaac agatcaccat gcaaaatcac tggcgaaact ggcttcagag
    17041 aaaaagagga tcttttatct cctttgtcca atctgaattt ccgcaaaaaa caagtgtata
    17101 tattaattct ttattatggg gctataaaga tgcaggattc agagaaccag aagaaatttt
    17161 tagggagagt ggtttgctgc atctgttcag tctatcgggt ctacacatcc aattttattt
    17221 agggtggctg tattatttat ttcgacgtat cggatggcca ctacacgtca gtattattcc
    17281 gttgagtcta ctaactatct gttatgtttc tattgcagga agttctattt ctgttttgcg
    17341 tgctagtttg ctgtttttat tgcgattgct agtcaaattg ctgaataagc attattccac
    17401 catggactta tttgcagttg tcttttggct tcttttacta tttgatcctc gatttctttt
    17461 tcatgcgggt ggacagctta gttttttcat gagttttttg tttatcctga tttcttttga
    17521 tggagattgg ttgaaaaaaa cggcctctca cgtcctgttt actatgatca cgatgccgtt
    17581 gattgtatgg catttttatg agtggcctat tttaggtagt ctttttacat tactgattgc
    17641 accggtattc aagtttcttt ttcttcctgg tgtgttattt ctcacactct tcaatcgctg
    17701 gctgccggaa actttacttt tgctgataga agagggatta atcttatttg agcgaataat
    17761 cgatttttct tcagggtcgt ctctcattat aggacgtttg ccccttgtgc tatctgggat
    17821 gtatattttc ggattactga tttgtatgga taggttgaaa gaacaacctg tgaaacactt
    17881 gttttatgtt ggtctttttt cttttatttt tttgactttg ccatttttac gcttttcttc
    17941 aacgatcgct tttatcgatg tcggtcaagg agacagtatc tttttgcaaa gtccttttcg
    18001 aaaagaaacg attttgatcg atactggagg tcagttacac tttgaaagag aaaagtgggc
    18061 gcaaggtatg atacgtcctc ctgctgaaag aaatatcgtt ccatatctaa aaggtcaggg
    18121 gataagtgta atcgataaac tcatcttgac acacgacgat acggatcatg tgggagaatt
    18181 acccacgtta tctcagcatt ttactatcaa aaaaatttat atcggttggg gcgctggacg
    18241 aaatgagcca ttacaaaggc atttatctga agctcaaaaa aatggtactg agatcattga
    18301 aatcaaacat ggggacagga tcagcggtta ttatgatctt tatgtattga ctccttttga
    18361 aaagggagag ggaagaaatg aagattcgat tggtctatgg atggaatata acaataggcg
    18421 ctttttattt ttaggagatt tgaatcaagc aatggaaaaa caattgcttt tgatttatcc
    18481 taatctgaaa gccgatgtag tcaaattagg tcatcacggt agccgtacgt caagtaacac
    18541 agattttctt tcccatattg aagcaaaaca tgggattata tcctgcggcg taaataatcg
    18601 ttatggtcac ccgcacagcg aagtattgga gacactagaa gaaaatcaga taaaaacatg
    18661 gcgaacggat caacaaggaa tgatcaccta tcgctggcat ccagtttttc atcctcatgg
    18721 gctagtggaa acaatgatag actagtaatt ctcatctgct catggtagga taatttttga
    18781 aagtggtgag taatttgagt atacaagcag agttacaaaa aatacgtaaa gaaaaacttg
    18841 catcttgtta cttgatttta ggaacagaaa agtttctcca agatcaagtt cggacagaaa
    18901 ttgtcaaaaa aatccaatta gagggcgaag atgacttaaa ttttttaagt tttgacatgg
    18961 aaaatgcaag tttagatgag gtagtagctg aagcagagac gttgccgttt ttcggagatc
    19021 aacggttagt attcgtagag aatccttatt ttttaacagg tgaaaaagta aacaatggaa
    19081 tcgaacaaaa tactgattta ttgacggctt atttgaaaga accattagaa tcgactgtat
    19141 tagtattctt tgcgccatat gaaaagttgg atgaacggaa aaaagtaacg aaacaattga
    19201 aaaaaacagc aattatcatc aatgtccaac agttgaatga aaaagaagta cgtcaatatc
    19261 tgatgaatac cttagagaat tcctcaatca aaatggaacg aagtgcaatt gatttattct
    19321 tgaggttgac cgacttagat ttatccaaaa tgatgagaga gttacagaaa ttggtccttt
    19381 atggacaaaa tcaacagcaa atcacggtaa gagaagtaga agaattagtt cctaaaacgt
    19441 tagaacataa tatttttgac atgacccaat atattttaaa agggaagacg gaacaagctt
    19501 tgcgtttata cgaagattta gttatgcaag gggaagaaac aatcaaaatt aatgcgattt
    19561 tgctttctca attacgttta tttttacaga caaaatttct tgtaaagatt ggttatcagc
    19621 aggcaaatat tgctgaaaca ttgaaaatcc atccatatcg tgtaaaactt gccatgcagg
    19681 aagtaaaaaa attcgatgaa catttgctgg tacagttgtt tgatcaatta gttgagatgg
    19741 attatcaaat caaaacggga caaatcgaaa aagaattaag ttttcaacta ttcgttttgc
    19801 gcacagggca gttgttaaga aatcgataag aagaaagacg agggcaaagc atgcgggaag
    19861 gtcgtttgtt tttgtccttt ttttgacaaa taaaaaaatc ggccgaagcc gattctttta
    19921 tttagcgatt tttttgctta aacgagattt gtcgcggtta gctttgtttt tgtggattag
    19981 accttttgat tcagccatat caatagcttt aacagcttct ttatataacg catctacgtt
    20041 gtcagcacct gaagctacag catcttcaaa ttttttgatt gcagtacgca tagcgcttgt
    20101 ttgagatgaa tttttcacat tagcgttttc gcttgtacga acacgtttga ttgcagattc
    20161 aatgtttggc attagtttca cctccgataa cttaagttct tacgcgtgtt accgcataat
    20221 tcaacattca ttattatacc taaaggcagc gtgctttgca atatgaacat gacaagtttt
    20281 tttccttaac agtcttttat taggattttt tttcagtaaa aacggatagt acaagctgaa
    20341 aaaaatcaaa aagacgctat tgtgggaggc aatagcgtca aaccaaacta gatttttatt
//
LOCUS       DADQCX010000051        20148 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.051, whole genome shotgun sequence.
ACCESSION   DADQCX010000051 DADQCX010000000
VERSION     DADQCX010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.051"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            11..1438
                     /locus_tag="J8R83_001678"
     CDS             11..1438
                     /locus_tag="J8R83_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAZ9574808.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1530..1895)
                     /locus_tag="J8R83_001679"
     CDS             complement(1530..1895)
                     /locus_tag="J8R83_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAZ9574809.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1892..2257)
                     /locus_tag="J8R83_001680"
     CDS             complement(1892..2257)
                     /locus_tag="J8R83_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAZ9574810.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2449..2697)
                     /locus_tag="J8R83_001681"
     CDS             complement(2449..2697)
                     /locus_tag="J8R83_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574811.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2696..2824
                     /locus_tag="J8R83_001682"
     CDS             2696..2824
                     /locus_tag="J8R83_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAZ9574812.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2881..4575
                     /locus_tag="J8R83_001683"
     CDS             2881..4575
                     /locus_tag="J8R83_001683"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAZ9574813.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4675..4848
                     /locus_tag="J8R83_001684"
     CDS             4675..4848
                     /locus_tag="J8R83_001684"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574814.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5226..6359
                     /locus_tag="J8R83_001685"
     CDS             5226..6359
                     /locus_tag="J8R83_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAZ9574815.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6390..6710
                     /locus_tag="J8R83_001686"
     CDS             6390..6710
                     /locus_tag="J8R83_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574816.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6739..7203)
                     /locus_tag="J8R83_001687"
     CDS             complement(6739..7203)
                     /locus_tag="J8R83_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9574817.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7335..8588)
                     /locus_tag="J8R83_001688"
     CDS             complement(7335..8588)
                     /locus_tag="J8R83_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574818.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            8702..9889
                     /locus_tag="J8R83_001689"
     CDS             8702..9889
                     /locus_tag="J8R83_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAZ9574819.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            complement(10091..10408)
                     /locus_tag="J8R83_001690"
     CDS             complement(10091..10408)
                     /locus_tag="J8R83_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9574820.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(10434..10754)
                     /locus_tag="J8R83_001691"
     CDS             complement(10434..10754)
                     /locus_tag="J8R83_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9574821.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(11218..12633)
                     /locus_tag="J8R83_001692"
     CDS             complement(11218..12633)
                     /locus_tag="J8R83_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9574822.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(12650..13966)
                     /locus_tag="J8R83_001693"
     CDS             complement(12650..13966)
                     /locus_tag="J8R83_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574823.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(14116..14814)
                     /locus_tag="J8R83_001694"
     CDS             complement(14116..14814)
                     /locus_tag="J8R83_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAZ9574824.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(15103..16092)
                     /locus_tag="J8R83_001695"
     CDS             complement(15103..16092)
                     /locus_tag="J8R83_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAZ9574825.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(16172..17005)
                     /gene="msrA"
                     /locus_tag="J8R83_001696"
     CDS             complement(16172..17005)
                     /gene="msrA"
                     /locus_tag="J8R83_001696"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9574826.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(17180..18814)
                     /locus_tag="J8R83_001697"
     CDS             complement(17180..18814)
                     /locus_tag="J8R83_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574827.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(18801..>20148)
                     /locus_tag="J8R83_001698"
     CDS             complement(18801..>20148)
                     /locus_tag="J8R83_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574828.1"
                     /translation="FFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT         6361 a         3945 c         3446 g         6396 t
ORIGIN      
        1 aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc tgtttttatg
       61 tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc tcctgcatgt
      121 ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg aagaacagat
      181 cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac atatacctcg
      241 atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt gtctgcttta
      301 tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca tctctgtcag
      361 caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg ggatcgaaat
      421 cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc ttaatgtgtc
      481 gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg aacgtgccga
      541 tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag aaaataaaga
      601 aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg ctgtgacaat
      661 agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg tcgaatcagc
      721 atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct ttattttgac
      781 actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg aagactttca
      841 acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag ttgctacctt
      901 tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg cgctgattca
      961 tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat tttatctttt
     1021 aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca gctggtccag
     1081 ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg tgatcgaatt
     1141 gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca caaattcgga
     1201 tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg attttcaagt
     1261 tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc agtcctcaaa
     1321 ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg aaaatattat
     1381 tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa acaaataagg
     1441 ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat ttctgtaaca
     1501 atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac gggtccgatc
     1561 tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc tagttggaaa
     1621 atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac aagaatttcc
     1681 aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc gctgactcgg
     1741 tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat tgatagacaa
     1801 acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag tttttcgaaa
     1861 tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt ctttgttttt
     1921 ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg ataataataa
     1981 gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg atatcagcaa
     2041 cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt gtatctgcat
     2101 tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa agtttgaata
     2161 gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa atagcaatga
     2221 tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac tttcttttaa
     2281 tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt aaaagttgtt
     2341 ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc tccctccatc
     2401 cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt agtccgtcat
     2461 cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc taaaaataga
     2521 accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta caggaaaatc
     2581 agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca tttggcattc
     2641 taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt ttttcatgag
     2701 taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg ctgcatatct
     2761 aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat tcgaatcaat
     2821 ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg aggaatcaca
     2881 atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc agcggctgtt
     2941 tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc attggatgat
     3001 cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg gaataaaaac
     3061 catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct taattaccgt
     3121 acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga gccagggatg
     3181 actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga caaagcacgt
     3241 ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa taataaagac
     3301 cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa actagacaat
     3361 atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa cttctggttt
     3421 atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt gcgtcgctat
     3481 atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt caatcgaaca
     3541 cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa agaacaagga
     3601 tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac accgatgcaa
     3661 gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga agaagaatac
     3721 gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac agattcagct
     3781 actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc agcttctagt
     3841 ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa attctttgct
     3901 gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca tttgttgttg
     3961 aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc atttatttca
     4021 accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt cgtgcatcat
     4081 caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta tttcctttat
     4141 ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg aaaagaaatg
     4201 ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa tattcgtgaa
     4261 aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat gccttatgct
     4321 tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc taaacattcg
     4381 accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat ctttactgaa
     4441 caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat tcctatgtcc
     4501 cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg tgccgcaaaa
     4561 aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
     4621 accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc gcagatgcaa
     4681 gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca agtaataaga
     4741 gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt accgcagatg
     4801 caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt tcgagtatga
     4861 agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt aataccgaga
     4921 aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt gaaaacaact
     4981 attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac aactatttca
     5041 atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa tacataagac
     5101 tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa gatctccttt
     5161 aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg aaaggagcat
     5221 ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga aacgtagatg
     5281 atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca gccatttgcg
     5341 gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg tatgttgtag
     5401 gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca ttgaaaaaag
     5461 ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc tgcctgaatc
     5521 acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg cttttcggat
     5581 ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga gttccttatg
     5641 cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa gttttatttc
     5701 tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta aaaaaaggcg
     5761 atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa ttcgctgtta
     5821 tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta gataaagcgg
     5881 ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct ggaacagaat
     5941 tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga atggacggat
     6001 tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc acaatctctc
     6061 cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta actggtgttt
     6121 atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat atcgctgtca
     6181 agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg attgcagaag
     6241 gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa gcagcacaag
     6301 catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg aaaccttgaa
     6361 ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat acccatgaga
     6421 tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc ttctatttcc
     6481 aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt ttctatattt
     6541 ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat ttttatttgg
     6601 ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac atttttattt
     6661 acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga gaatttttca
     6721 aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag cggtcgtccc
     6781 actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa acgtggtatg
     6841 atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc tgatttccgc
     6901 taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca gggcacaaag
     6961 atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg ctcctccgac
     7021 gatggtttct ttttcatcta agaccacata ccattgagga atactttcct tattagcgat
     7081 tccagtacga atactttcct catacacaac agcaggaact ccccattttg atgaaaacca
     7141 attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt tatatgtaac
     7201 caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag tctttatgaa
     7261 aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc acttgttctc
     7321 cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat cgtagctacc
     7381 ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc tagtacacca
     7441 cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac ccatggaggc
     7501 ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac actaactaag
     7561 accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat aggtaaccca
     7621 aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt tgttacaacc
     7681 atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc taaagttgca
     7741 cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat aaacggtgcg
     7801 ctatgtccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt gattgtttgc
     7861 atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa tggtgtgata
     7921 aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg ttcttggacc
     7981 actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat tgcagcaact
     8041 aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc ttttgcaact
     8101 gccggtggca caccatcagg cattttgatg atcaattttt catttccgct taaacgtaca
     8161 aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt tgagctcata
     8221 cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc ggaaacaccg
     8281 tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa gacagaaaga
     8341 atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc accaccaaaa
     8401 attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat tactgctaat
     8461 gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc aactaaatgc
     8521 cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa tgcaacaaat
     8581 ttatccataa atcgattacg tccatataat tgtgtaaaag tgaagcatca aaaaagccat
     8641 tgatctcagt taggagtaca atgttttttg cagaaaacat actcgaatag gactgatatc
     8701 aatgactcaa gtacatttta cttttgaaag cgaagaaatt caagcaatta taaacgaaag
     8761 cggtgcgaat gataccgcaa aaacacttat gactatcatg tttaatcagc tgatggaaga
     8821 acaacgaaat caatatattc aggcaaatgc ctatgaacgt tcagaagaac ggcaatcaca
     8881 aagaaatggt tactacgatc gttcgtttac aactcgaatt ggtacgttag aacttcatgt
     8941 tccacgaacc agagacggta agtttagtcc tactatcttt gaaagatatc agcgaagcga
     9001 aaaagctttg atcgctgcca tgattgaaat ggtcatttct ggtgtctcca ctcgcaaagt
     9061 aactaaaaca gttgaactgc taacggatgg tgcgactgtt tctaaatcat tcgtttcaaa
     9121 tctgatgaaa cagttggatc catttgtttt tgagtggaga aaccggagcc tagaaggctc
     9181 ggaatatcca tttttcatgt gtgatgccct gtatatgaaa gtaagggaaa atcatcgtat
     9241 tgtctcaaaa ggtgtatata ttggtatcgg cattgattct gatggacgac gtacgattct
     9301 tggttttgat gttcaagacg gcgaatcgga agataattgg gataccgttt ttcaatcgtt
     9361 cgttcaacga ggtttgttcg gtgtaaaact ggtcatttct gatgcacaca aagggttagt
     9421 taaggctgtt cgcaagaact ttttaggtgc gagctggcaa agatgccaag cccacttttt
     9481 gagaaatatt tttgataagc tgccaaagaa agtttcttct gatgtaaaag acgagttgaa
     9541 gagtatcttt aaagcctctg aacttgaatt gacacgtgaa agaaaagagc acttcttgga
     9601 aaaatatggt tgtgattcaa aattaagtgc tgcttgcgac attttagaaa acggctttga
     9661 agatgctatt caaattttgt cttttcctga aaatatccgc cgaaggattc gtacaaccaa
     9721 tgtgttggaa cggttgaacg aagagattcg ccggagagaa cgagtgattc ggatttttcc
     9781 aaatatcaat tccatcactc ggataattgg aacacttttg atggaaaaag acactgagtg
     9841 gctggcttct ccacgaaaat atttagaatt taattcgaat aacatttagc accatgaacc
     9901 tgtgcgagtc tcttctttct gaggagagac atcaagagtc gctgcgctac tgctcctgac
     9961 ctctctcctc agaaagaaag gcatggcagt taggttcaca acgcaaaaca ttgtgctttt
    10021 gatgaggttg aacttttaca caagattgtg gacttgactc ataaatcttc cctcttttct
    10081 ttactgtaga ttacgcgttc aatcgacgat acagatcaat gatctctttt gctaaatctg
    10141 taaaagctat agatgtcatc agatgatctt gactgtggac cgtcaaaagc gtgacttcaa
    10201 cgtgatttcc ttgtgcttct tgtgtcagca tctctgtttg agagtgatgt gcttggacta
    10261 aagattcctc tgcatctttg attttttcat ctgctaaagt gaaatcacct tttttcgcag
    10321 cagcaatcgc ttccattgca tcgctttttg catttccgcc aaacatgatc agacccatga
    10381 tggcttctag atttttttga tcttccattt attgtatcct ccgataattt ttattatttg
    10441 tttattagtt tttctgcttg gtcgagtact ttttcaccat tcatcatgcc atagtcagcc
    10501 atattgatta catctaaagg aatgccttta ggtgctagct tttcagcaaa ttgattttgc
    10561 ataaagcgta cttgcggtcc taaaagtaaa acgtctacat ttttagattc tagttgatta
    10621 tccgcatctg aagcagatac agcaaagatg tctgcttcca ttccttttgc ttctgctgcc
    10681 ttttgcattt ttgtgactag gagacttgta ctcattccag ctgaacatac aagcatgatt
    10741 gttttctttt ccattttaaa cacgttcctt tctatactta cacttgtata taagcaagta
    10801 gcgtgccaac tttaaaagcg ctttaaaaag ttgatatcat cacatttaag gtctatacca
    10861 agttgcatac acactaaaaa agaaagcgca cactaaacac acaaattaat ttttattacc
    10921 ttttttcttt taacgtgcac aaaaaaagtt gtgacacaaa acttgtcaca acttttttca
    10981 aataaacggt attcaaaagc ttgcatctgc ggtaataagt ccaaccaagt taaaaacata
    11041 agatgttgtt tttactttgc tattcttatt acttgatgca ggacagcttt ttcacaacct
    11101 ctcaataaac ggtgttcaat cagctgaccc tgggtattag ctcaaaacgc tggattcaca
    11161 acctctttta tttcaaataa ccagtaaata caatgaacat ctacaaaaaa cttctattta
    11221 tttatagatt tcgtcaggca aatccaattc tctcttatca atcaaagtct gataccacga
    11281 agcagatttt ttcaatgttc tgcttcgttc atcgttcaat tcgattcgaa ctaatccata
    11341 tcgattctta aatgcattca ttggtgacac acagtcagtg aatgcccata acatatagcc
    11401 ttcgcaattt gcgccttctt ctgttgcttt gatcaagtaa tgcaaatgct gtccgataaa
    11461 ttcgatacgg taatcatctt gcacgattcc tttctcatcc atatactgtt cttcatattc
    11521 tcttcccata ccgttttctg ttatcagcca agggatatta tgataatttt cttttagata
    11581 catggctata tcatacatga ttttcggata gatttcccat cccctggaat tattcatttt
    11641 cttcccaggt aaatcaaaga cttcataata tcgttcagga tggaaaggtg tctcttcatt
    11701 ccattgataa cgaggggcgc gaacgcgttt aggataatat tgattgattc caaggaaatc
    11761 tactgtatga tgctgaatcg tttctaaatc ctctgttgca ggatcgaaat aaatcgattg
    11821 tttttgacac aactccagga actcttctgt gtagtatcct tttaccatcg gatcaaaaaa
    11881 tactcgatta taaaacaaat catacatata agcagctttt tggtcttctg gagaattgga
    11941 tcgagcatag accatttcag gatttaaaat acagccaatc cttccaccat aatttccgct
    12001 gcggtaaatc tctactgctt tagccgttgc taaaacttta tgataattcc acatcatcca
    12061 cttttttgtg ttttgttcat gcggccagcg aacagcatcc aaatagcaac gcgtttgggg
    12121 aacgattggt tcgttgaatg taaaccagtt ttttacccta tcaccgtaac gatcaaaggc
    12181 aatttgagca tacttagcat aaaaatcaac tacttttctt gaagaccagc catcatattt
    12241 ttccaaaaga aaagctggga cttcataatg ttccaaacaa atcatcggtt ctacgtctgc
    12301 ttcgatcaaa gagtcgatca tttcacttat atgctgagca tattcttcat ctactataca
    12361 gttctcataa tcagtaaaaa aacgagccca attgatagaa gtccgataat gtgtcagatg
    12421 gatggatttc atcagatcca catcctgctg gtattgttcc ataaaattag ttgctacggc
    12481 tgggccatac ccattatgcc aaacaaaatg ttcattttta taccagctat ctataaacga
    12541 atcctgtcct tctttttttc ctttccaacc ttccgtttgc caagcagaag atgcagcacc
    12601 aagaataaaa ttttttggaa tagtaatttt catgatttcc tcctgttttt tagatcccat
    12661 cattttccac acgatttgct acttttacaa atggcagata gatcaaaata gaaacaataa
    12721 tacaaacaag ttgcgtaata actgcaccga tatttcctgc tgttgccaga taagcattga
    12781 cgatcggcgg cattggccaa gggaccatta caactgcttt cgccgcaaat cctaaagcgg
    12841 ttgcaaaata accaatcgtt ccagtgataa gaggcgttaa gataaacgga atagctaaaa
    12901 ttggattcag catgatcggc ataccaaaaa taactggttc attgatgttg aagatcccag
    12961 gagcaaggga taacttggtg atttgtttca tatcttcccg ttttccaact aacaatactg
    13021 caatcagtaa accgatcgtg actccagacc cgcccatact catatacata tcccaaaatg
    13081 gcatagtaat aatgttcggt acttcttttc cagcttcaaa agcttccgta tttacagcaa
    13141 ttgccgctaa aagcaacggt tcccgtatcg gcttcaccat ttgatttcca tggataccaa
    13201 tcacccaaaa gacttgcgca ataaacatca atagcaaaat acccggtaac ccttgtacga
    13261 caccttctaa tgggcgttgt acgacattgt aaatgatatc ataaaggtac attcctgtaa
    13321 gttctttgat gataaatccc gcagccgcga tacccgatac agtcagaatc gtcgggaata
    13381 aagcagaaaa actagcagaa acattcgttg gcacggtatc aggcattctc agctgtagtt
    13441 tcttctgttt cctcaaccag caataaagtt caatagaaag gatggagacc aacattccca
    13501 aaaataaccc tttcgtatct gtatattgtt tagccaatac gttttctact ataacagtct
    13561 gattttcatt cactaattca taaacagttg gattaacaga taaataagac atcactgcga
    13621 tgataccagg gaatacacca tccactttat tcagcttggc taattcgatc cctatcagaa
    13681 aaacagcata gatggtcaag aaacttagtg tgacatagct gatggcagat gcgataggct
    13741 ttaattcttc taaaaaacgc aagaaactta tctgtgctaa gccattttcc gagtcaaaga
    13801 ccattgctga aaacaatgtg ccaaaagcac ccgtaataat taccggaatc aatgcagcaa
    13861 atgcgttttt tatcaccatg atatacctta aattattgat tctcgttgcc acgttcccta
    13921 aaacattggc taatttatcc ataaaactca ttccagatcc cctcattcct gcttcttctc
    13981 cttgacgtca tctctttttg tctattagtc agcgcttaca tttcgatgaa cagaaactat
    14041 ttactcctct tttttaccaa atataaaaca aaaattcatc tgatgtattt atcataaaat
    14101 acatcagatg aactgtcaat tagtttcttt ttctcctatt attttctgta attctctccg
    14161 atttattgcc atatggacag tcattgcatc aaacgcagca agtgcattcc gcctttcgat
    14221 ggcctgaacg atctctgtat gaatatcgat cgtctcgatt ttcagatgct ggatatcata
    14281 atttttatta aacaaagcaa ttgattcatt aatgattggg ataatatgca gcaaggctac
    14341 gtttccgcta gcttctgcaa tcatcgtatg aaaatcgatg tctaattgaa catgttcttg
    14401 tgtgccttct cgaaaagaag tttcaatctt ttgcgttaat tttttcattt ggacgatttg
    14461 attcttcgtt gcatattccg ctgccaaacc tgccatctta ggctccaata aatatctcag
    14521 ttcaaataag tctcgtatca tccgatcctg atcttcaatc aaagaaaaac cgagtgggtc
    14581 attggcaatc cctcgcttat cactgacaaa tgtccccgct ccttgccgaa cttcaaggat
    14641 attcctggaa gctagagccc gcacagcttc tcgcaccgtg cttcgcccca cctctaaata
    14701 atcggacaat tcatattcat tcggcagttt atctcctact tgcaactgca tttcctttaa
    14761 atatctaagg atcttgtcag tagttacttc tactagggtt ttattttctt ccaaaccaca
    14821 tacctccttt tcatctgatg tattttttcg taattattat aacacgtttg aatcatctga
    14881 tgattttttg tatacaaaat tgattaatcc gttcatagac atacaaacga agaagatatt
    14941 taccataaaa aagactagga taaaattcac tcctagcctt cgatcatttt tattttgaac
    15001 gacaaaaaat atgatgttca ataacagacg atcttcattc gattcttgat gtcatctttt
    15061 gtttttttta atatatggat aaaaagtttg attacatcgt ttctattcta gaatttggtc
    15121 gattctcaat tcttcttctg gtgagaaatc taaattatcc atcattcgaa cactttcttg
    15181 taactgactt aaccgacttg ctccgaccag tacacttgta acagattttt gtcgcaaatt
    15241 ccatgcaagg gccatttgcg ctaatgattg tcctcgtgat acggcgattg tttgcagtgc
    15301 tttgattttt tccagagttg atccaacttg ttcttctgaa aggaatggta tttccttacg
    15361 atgtgctcta gaatcttcag gaataccatg tagataacga tttgtcagca acccttgagc
    15421 aagcggactg aacgtgattg cccctagccc ttcttcttct aatactggag atagatcgtc
    15481 ttctagtagt gcacgagaaa acatattgta gcgcatctga tgaataatga acggtgcttc
    15541 ctttcttttt aaaatttcag tcattttttt tgtatcttct ccattatagt tggatatacc
    15601 aatatataat gcttttcctt gtcttacaag ttgcatcaaa gcttctgctg tttcttccaa
    15661 aggtgtatca gggtctgggc gatgatgata gaagatgtca acataatcta gccccattct
    15721 ttggagactt tggtcacaac ttgaaatgat ggatttacga gagccccatt ccccatatgg
    15781 cccttcccac atatgataac ctgctttgct agaaataatc agttcatcac ggtaggcttg
    15841 aaaatcttct ctaaaaatac gcccaaagtt tttctctgca gctccagcag ggcctccata
    15901 attattcgca aggtcgaaat gggtaattcc catgtcgaat gcgcctctta aaatctctct
    15961 ttgattatgg ataggatcat aatcaccaaa attttgccat aatccgagag ataaaatcgg
    16021 taatttcaaa cctgaatgac cggatttacg atattccatt ttttcataac gtgcactatc
    16081 tgcaatatac aatttttctc ctcctcatca aatcttttta aaacgctttc ttttttctat
    16141 ttttagttta ctacatttta aagaaaagga gttaatcaaa atgatttttt cgtatatttt
    16201 tttgccattt gttttttact cgttgataga tcagaaattg attacgtgct tgctggattt
    16261 ttttataacg tttcggttgt tttttgtaaa attgctgatg atagttttct gctggccaaa
    16321 acgtaccggc tggttcgatt tttgtgacga ttggttggtg gaaagttcct gaactgtcta
    16381 gtttctgttt tgattgttcc gctaattctt tttgtcgttc gacttgataa aaaatcactg
    16441 gacgatattg cttccctcta tcttgaaatt gtccaaatgt atctgtggga tcagtaattt
    16501 gccaatagat tgtcagcaac tcgctataac ttatttctct tgtgtcataa atgatctcca
    16561 cagcttccac atgacctgtg taaccaccac ttacttgatc ataatttggt ttttcaacat
    16621 gtccgcccgt gtatcctgac aaaacagata ggatcccttt tttcgattca aacggctcga
    16681 ccatacacca gaaacatccc cctgcaaata ctgcacgttc ttgatagtca gcatcttgca
    16741 tggcatgctt ggaaaagtca tatttttgct ccttatcaaa tccttccgta atcaataaat
    16801 aaaagtccat tacatcaggc gtcagattca ttcggatagc taatggacgt agtgttgctt
    16861 ctagttttga taactgttct ttaacggata tattttctct tatgtcattc tttgtctgaa
    16921 tcaatacttt tcgttcccaa tctcgtgtat tcggattcaa aatcagatta taaagtgttt
    16981 gaatgaatat ttgttcctca tccatagatt ctcctccttt ccgaagaaga caagctagtg
    17041 actttagctg taatttatca taaagtgagg aaataagcga ttacttcatc cccctacaga
    17101 tttttcgtat aaaaaagaga gaatccttat cgacagattc tcctttttaa tcaatttatt
    17161 ttataaatga aaagttaatt taccttttat ggaaaactat tttaaaaaat aaacataaat
    17221 atgcagttaa tgtaacaaga taagaaataa tagtcgttac tgtataactt gtgcttactt
    17281 taatatcagc aactcctttg actccgctta tttgtaccaa tccattagca ttcacctgct
    17341 cctttacagg ttgatgattt atttctacat tcgttcctaa ataagcatat acaggaagtg
    17401 tgattacttg gctcttctca ttagttactc tatatatgat agaactacca gttgttttat
    17461 aaggaaggtt tacccattga ctgccaatct ttgcttcgtg ttttattata tgctccttat
    17521 tctccaatga agcgatagga gaataatcat ataaaaaata atccattcct ttagtggtat
    17581 acgcctctac tgtttctttg tttacaacaa tatgtcccgg ctgagaaatt attttttgat
    17641 tgaaattttt tttactagaa acagttaaag tgattaataa caaaacagtc ataaataaat
    17701 aaaatagttc tcttgtctta ttgtatcttc tatttttgaa aaatatcatc gttaatatca
    17761 gagaagagaa tattatttgc aagcttaaga tccgccaagg aaattgtaac aatttggctg
    17821 gcgtattttg cagaagatac catggcacca aactagttgt agctagccaa gtcaaacacg
    17881 taccataata aatctttttt tctatgtttg ttaatttttt aaataaaatc aggggaatac
    17941 ataaagataa cagaccaact agtcccattg agtaagtagt taagtcgttg ttcatagctt
    18001 cagtcagact atcgaacaca ttagatgcat gagcatataa atttgtcacg ctaggtttgt
    18061 tgattttttg gtagagcatt tgttcaaaca tcggatacca aaaagcactc gtcagaacca
    18121 atgtcattcc tgccgcacta aataattttt taaatatagc aataaaatct gcattcttga
    18181 aacctttaga aaccaaacga ataaaaataa aaatgataat taatgctgta ctcattaatg
    18241 ttgatagtac atggctgtac actagcaaac tcatactcaa tgctagcttt acagacggat
    18301 acttttcttc ttttccagag atgatttgat aagcataaaa taatacaggg ataacaagtg
    18361 ttattgcgat agcttcggca attgcggaac gatagtagat gtctactgtc cgataagcag
    18421 agaaaatata gagacaacta aataaaaatg ccgctttttt ttgttttaaa aaccgctcgc
    18481 cataatgata agctacgagt gttgtacaca agttcaataa ccaaacgtaa ataatatagc
    18541 ttacaatcaa attttttgtc atccaatata acattacagc tggaaaaaaa gtcagaaagg
    18601 gataaaaata atttacacca tatccagtat aattgaatgt ctcataatta atcggactgg
    18661 taaaaatagt cgataacccc ttgattcgag ataagtgaaa agaaagatct ccagtggtat
    18721 aaatactctg tgtatttttg aaaaagatga aagaatatat actactaact ataattaatc
    18781 cactcaatat tactactttt ttatttattt tcattcttct tgtttatctc ctttttagtc
    18841 acatatcgag aatctttcaa cttattaggt gcaaatcgtt taaaacttga atacaccact
    18901 aaacaataag tcagaatact gatccataaa gccatgagag cagttggagt atattttgtt
    18961 gtaatttcta tcttattttc tccagcattt acatccacat tcactaagcc atgtttttta
    19021 taagagtcat ttacgacttt accgtttact tttacctgtg tacctaaata agcatatact
    19081 ggtactgtca ctttttgctt tttgttgctt gccactgtgt aagtaatgtt attatctgca
    19141 gctttatact tccctttttc ccacgattct cctactttta cttcatgttt ttctaagtga
    19201 ggcctttctt ttatcgcttc tgttggggcg taatcgtata atcctcccat atctgatgtt
    19261 gtataacgtg ggagtgtttc ttcattgata acaatatgac cgtgttttga ttggataact
    19321 tttgcgtaat tttcttttgc tgctatagac gtgacgagta gaaacaccac agtagcgcca
    19381 atgattaacc atgaatattt tttattcata gtctttttca taaaaacaag cgttatgatc
    19441 attgaagaaa aaaagatttg gatacctaag atacgccaag gaaactggag taagcttatc
    19501 ggtgtttttt gaaacaaaaa ccatggaaat aaattagtta cgcataccca tgtagaaact
    19561 acgccaacat agatgatttt ttcttttttc tccatttctt tcagtatgaa taaaggaaaa
    19621 atcaacgcaa ccaatcctaa taaccccata gtgtatgttg taatatcgtt atttaacgct
    19681 tgaatgatac tatctgaaat agaaagtgct tctagctgca aatctgtttt gaagggactg
    19741 tgtatttctt gataattcat ctgctgcaac ataggatacc aaaaatagct agttaatgca
    19801 caagtcaaaa aaacagcctt tactaaattc acgaccacaa attttatatc gttttttatt
    19861 tgcttgctta aaaacaaacg aactataatc atacaagcaa tcaatgcact acacaatagt
    19921 gtagttaaga catgagtata cacaagtaga cttatactga cagataaagc gatgactttt
    19981 ttttctctat tgaatatcaa tccataagca taatataaaa cagctgggat aatcgtaaga
    20041 gcgattgctt ctgcaattgc ggatcgataa tagatatcaa ctgttcgata agttgcaaaa
    20101 gtatataaac aactaaataa aaaagcagca tctatctttt taaaaaac
//
LOCUS       DADQCX010000052        19765 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.052, whole genome shotgun sequence.
ACCESSION   DADQCX010000052 DADQCX010000000
VERSION     DADQCX010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.052"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(356..1540)
                     /locus_tag="J8R83_001699"
     CDS             complement(356..1540)
                     /locus_tag="J8R83_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAZ9574829.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(1565..2572)
                     /locus_tag="J8R83_001700"
     CDS             complement(1565..2572)
                     /locus_tag="J8R83_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9574830.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(2744..3103)
                     /locus_tag="J8R83_001701"
     CDS             complement(2744..3103)
                     /locus_tag="J8R83_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574831.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(3075..3446)
                     /locus_tag="J8R83_001702"
     CDS             complement(3075..3446)
                     /locus_tag="J8R83_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAZ9574832.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(3463..3765)
                     /locus_tag="J8R83_001703"
     CDS             complement(3463..3765)
                     /locus_tag="J8R83_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574833.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(3782..4252)
                     /locus_tag="J8R83_001704"
     CDS             complement(3782..4252)
                     /locus_tag="J8R83_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAZ9574834.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(4227..4505)
                     /locus_tag="J8R83_001705"
     CDS             complement(4227..4505)
                     /locus_tag="J8R83_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAZ9574835.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(4502..5551)
                     /locus_tag="J8R83_001706"
     CDS             complement(4502..5551)
                     /locus_tag="J8R83_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAZ9574836.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(5508..6437)
                     /gene="cpaF"
                     /locus_tag="J8R83_001707"
     CDS             complement(5508..6437)
                     /gene="cpaF"
                     /locus_tag="J8R83_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAZ9574837.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            6569..8323
                     /gene="ade"
                     /locus_tag="J8R83_001708"
     CDS             6569..8323
                     /gene="ade"
                     /locus_tag="J8R83_001708"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAZ9574838.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(8421..9083)
                     /gene="trmB"
                     /locus_tag="J8R83_001709"
     CDS             complement(8421..9083)
                     /gene="trmB"
                     /locus_tag="J8R83_001709"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAZ9574839.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(9153..9932)
                     /locus_tag="J8R83_001710"
     CDS             complement(9153..9932)
                     /locus_tag="J8R83_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAZ9574840.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(10139..11350)
                     /locus_tag="J8R83_001711"
     CDS             complement(10139..11350)
                     /locus_tag="J8R83_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9574841.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(11343..12080)
                     /locus_tag="J8R83_001712"
     CDS             complement(11343..12080)
                     /locus_tag="J8R83_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574842.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            12218..12652
                     /locus_tag="J8R83_001713"
     CDS             12218..12652
                     /locus_tag="J8R83_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAZ9574843.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            12645..12989
                     /locus_tag="J8R83_001714"
     CDS             12645..12989
                     /locus_tag="J8R83_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAZ9574844.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            13169..14179
                     /locus_tag="J8R83_001715"
     CDS             13169..14179
                     /locus_tag="J8R83_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9574845.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(14248..15192)
                     /locus_tag="J8R83_001716"
     CDS             complement(14248..15192)
                     /locus_tag="J8R83_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9574846.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(15176..17896)
                     /locus_tag="J8R83_001717"
     CDS             complement(15176..17896)
                     /locus_tag="J8R83_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9574847.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFKQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            complement(17893..19113)
                     /locus_tag="J8R83_001718"
     CDS             complement(17893..19113)
                     /locus_tag="J8R83_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAZ9574848.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            complement(19394..>19765)
                     /locus_tag="J8R83_001719"
     CDS             complement(19394..>19765)
                     /locus_tag="J8R83_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HAZ9574849.1"
                     /translation="DAISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIV
                     PQNVSKGVVFDRLESIYNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKAD
                     YVTVSNDKDGVSQAFERILTI"
BASE COUNT         6023 a         3994 c         3286 g         6462 t
ORIGIN      
        1 tttattattc gatcaatgaa tgtttcggat cggttttcta gctaaacata aagcgaagaa
       61 taaagtcgac agcccacgag gctgatctaa aaatgttttt tctttttaca tatgtaatgt
      121 cccttataaa gatgaatgaa aataaaatat tgggattttc ctgaaaatca ataaataaaa
      181 tgccagtctt ttcccttttg accacttttc caagcaaaat tccctaagaa gatcctgtaa
      241 aaaagaaggg aaattgaagt taaattacca ttttgcggtc ttctccgcaa aaaaaacaca
      301 tgcaagaatt ccctcttgca tgcgtttcat cttttatcct aacgaatgct ttggcttagc
      361 cgcgcagacg ctccacatca cgggcaatca ttagttcctc atctgttggg atcactaata
      421 ctcttacttt tgattctttt gtagagatat ctacttcttc accacgcaat tcattcaacg
      481 ctggatcgat ttcacaacca aaccaagaca tacctttgat gatttcacta cgtacatgtc
      541 cgtcattctc gccgatacca gcagtaaaga caattgcatc aacaccattc atcgttgtca
      601 cataaccgcc gatgtatttt cggatgcggt ccacgaaaat gtcataagct aaacgaatat
      661 gttctttttc atagttcttt tcaagatcac gcatatcact agacaatcct gttaggccta
      721 gcagaccaga tttcttgttc aaaacattga tcatttcatc aatatcaatc tctaattttt
      781 ccattaaata tgggagaaca gctggatcga tatcacctga acgtgtaccc attgtcaccc
      841 cagctaatgg tgtgaatccc atagaagtat ccatggattt acctccatcg actgctgtga
      901 tcgatacacc atttcctaag tggcaagtga tgatttttag ttcttcgatc ggtttgttca
      961 ataattttgc cgcacgttcc gacacataac gatgacttgt gccatggaag ccatattttc
     1021 ttactttgaa atcttcataa taagacaccg gtaagctata taaataattt tgctttggca
     1081 ttgttgagtg gaaagatgta tcgaatacag ccacactcaa aatgtcaggt aaaatctttt
     1141 taaacgcttt gatccccatt aagtttgcag gattatgcaa aggagcaaat tctgctaatt
     1201 cagcaatgcg gtccattact ttctcatcga tcactactga atccccataa gtttctcctc
     1261 cgtgaacaac acggtgccct actccggtga tttcatcata agagcttaaa atttgcagtt
     1321 caatcaactg atctaacagc atttttactg ctacttcgtg gttttcgata tccatgattt
     1381 gttcgaattt ttgattatcg ccgtacttga tggtaaaaat agaatcttgt aaaccgatac
     1441 gttcgacgat ccctttcgca actacggttt cttctggcat ttgatataat tgccatttca
     1501 aacttgaact cccagcattg attgcaattg ttttagacat atgactctcc ttctcgttga
     1561 atgattacag agcagatgat ttccagtttt taaactcgtt gaaaaattcc gtcaccttct
     1621 ctggttcttt taatgaagca agtttcacaa gcaagacttc ttttacttgt tgtgcttgtg
     1681 gtcctttttt ctgtaagatc aaaatacttt tttgcgattg tttattacgg aacaattcat
     1741 ctggcaattg aatcattcct tgaagataac cttcttcttt aaaccatttt ttgatttctt
     1801 cactttgatc cgtttctaaa aatccactcg gcatcaaaaa caaaccaaaa ccatccggct
     1861 tcacatattt cattgattgc tctagcaata aatgatgtgc ataactatgg ccttcttcgg
     1921 tacttgttaa aaactctttt gctttttcgt cattcggata ataaccgatt ggcaaatcgc
     1981 tgattgcaaa atcgacagga tctattaata attcctgcaa cccgtcttga tgaaagtatt
     2041 gaacatttgc ttgtgtcaaa tcacttgtag aagctgcgac agccaacaat gtatcatcaa
     2101 tatccacacc aattccttct gtttggtacc ccgcattcga taggtttaaa agaactgtta
     2161 ataacaagtt gcccattcct gccgcaatat ccagaatctt aaccggtgct tttttatttg
     2221 tgtatagttg ttcaataaga aaaacaaata aaaaaccgat actatcagga gtgagttgat
     2281 ggttcgcctg caaatgttct gtctggctgc ccttcaataa aagtaattga gacagtctgc
     2341 gccattcttc tggctcgaaa gaaagtttct tcaactcttc ataaagagct gtgatccgtt
     2401 gcgttgtctc ttttgtcggc actccatcca ccacacgtac ttgataatca tctattaaat
     2461 tttctgcatt ttcgacatag gcttctaaaa aggaagttcc caatgcattc tgtaaaagct
     2521 gaatagcttc caggttttga ttaaaccctt gttccatttt ttctggtaac atggtgcacc
     2581 tcatttctag atatattata acaatttttt cacctgttta attctatcga acaattgaca
     2641 aaatttcaat cgttttcact gttttttatt tgtgaaacgg caaacatttt tttattaaaa
     2701 acagtgttat aacagaaaag agggcgtttt cacgaacatt ccatcattct gtactagtat
     2761 ctgtatcatt ttttacttct tctgtgaacc gaaagataaa cggtgagact tccacctcta
     2821 agaataggga ctgttgtacc cactgatatg ttacagatcc agttgtgtag taaaaaactc
     2881 cttccgaact ttcggcaagc gtagactgtt ccgataaagc catctgcttc attatttttg
     2941 ctatataata atttttgatt cgtatattaa gatccattga caaacggtag ctttctaatg
     3001 ctgccatcaa taaaaacgta cataaaagaa ataaaagcaa gacagaaaat aaaatagagc
     3061 ccttataaca ttttctactg atcgtttttt gtccatatgg catatccatc ttctccattt
     3121 tcaaagtgta cataaaaaga aattgtgtgt tctttttcca ataattgaag ctcagtgata
     3181 cttgttaaca taggttgatg tccgccggaa gttcttcttt tacgtatcat tgcctgatat
     3241 ctttcgatga tatactgttt atcctcgatc gtgtagtgca gttgctgatt tttcacagag
     3301 acattgtgac tgctcttgag ttcttcttct aattgtgcta aaaatattag ccactctttt
     3361 tgatctttac gctgcaaaaa ttcacttact tggatggttt gctgaatcaa aagattgaat
     3421 gtgagcaata gactgctcaa tatcatcagt ccaattagac attcaatcag cgtaaatgct
     3481 ggaattactt gttttttcaa tactgatcgc ttctttctcc atattgacaa acactttttc
     3541 gattactcca ttattatcga caatttggat atcgtatggg atcatttctt cccttcgctc
     3601 tggtcttttg tgatacatcc gctgcgtctt gatatcttca taaatcattc gaataaatag
     3661 cagttcctcc ccacttttct tttctgcctg aagcaaaaac agctggccaa agctcactaa
     3721 gtagacacag acagaagcga tcataagcgc tgtaagggac tccaacaaaa caaatcctgt
     3781 tttattcaat tctttttgta tagcgaccac tccctatctg gaattgatac gtaatcgtcc
     3841 gctctttttc ttcccaataa aattgataag cttttagtga actttcattc ccggttctag
     3901 cagcaaaagt aatagaagca tggcgtttca aggtaatctc atcaggaata tctaatactt
     3961 cccaatttat tttatctgga ttcggaacat gaaaaatgat ttgattctct tcactattcc
     4021 aataaaagcc tgtttggatc tgattcacaa tagcgatttt ttgcgtagaa tagattcgtt
     4081 tttcaaattg gccgaaaaat tgatagactg ccaattcatt cttccatgca gaaaatgcga
     4141 gaactggaaa agaaaggatc gttgtaagta ataaaatcag taagagtgat tcaaacaacg
     4201 tatatcctga tgctaaaacc ttaccttcaa ggccgctgat agatttctgc atgttctcgt
     4261 ttgatatagc cttcattcaa caattcctcc acagtaggaa ctcttccatt attttgaagc
     4321 gcatagagct ctttttgtgt gtctaccaac tggatgatcg cttcacgact ttcttggtct
     4381 acatgattcc tataacgcga caaattaggg acgaacaaca acactaatac actgatgatc
     4441 agtaagacga ttagcatttc gatcaatgta aaaccgctat aataagatat ttttctcttt
     4501 ttcatggcaa aacctcctct atgcttccgt aaacaggtaa taaaacagcg gcataaacta
     4561 ataaaatcaa agccgctacg cccaaaaaaa tgattggctg aataaaatgc atccagtgat
     4621 gaagacgttt gaaaagctgt tttcttgtcc attcgctgta aaaaatcagt tctttaccta
     4681 aacttccctt tgcctctccc tgtaaaacaa ttttactgaa ttcttctgat agaaaacgat
     4741 aattctggaa ctgctcagcc aatgacatac ctgcctccaa tccttgaatc aacttagagg
     4801 caagatgctg aatcagactt tcttgtttcg tttcctttaa gcagactatg atttgcctta
     4861 attcgaaacc ttcatgaaaa agctttccaa tctctagtga caaataagcc gattgataca
     4921 aggaatatat cggtccaatc aataattgtc tgcttatcca ttcactctga tcaacaggag
     4981 acaacttcat cagacgatac cttactagta aagccaatag agtaaccgct aggatgaata
     5041 gtagaacata ccaatgaaag acttgtatca gctgaatacc ccaatgctct tgcatgacca
     5101 ttcctgaacc aataagctga ggcaaaacga acaaccgcat actaaacaag atacctagca
     5161 aaaaggtgag caatagcatc ggatatgcaa gcagcttttt caaatcattg cgaaatcctt
     5221 caacaagccg aaactgtttg gcaatttcca acaaagttgt cggcagattc ccatgacgtt
     5281 cagctaactc gatctgtacc agttgctctg ctccatatcc tatttgcgaa agtacctcac
     5341 taaacgcttg cccttccttt agctgatgtt ggatatttgc caaaataaca ggtggaaacg
     5401 aacggatcgt gagtaataaa taaagggatt cttgcagact aaaaccagat aaaagcagtt
     5461 ctcccatggt ttgtgcaaac tggttttgct ggcttcttgt taatccttta gaatagttct
     5521 gactgccaaa tattttcctg agcttcttca taactttcct cccatgattt ttttactgat
     5581 tcttcctcca taaattgata actccataaa acagaaggat ggtgattggc atcttccaaa
     5641 agttcttgat aaatgacacc agctaaacat tcagatagct cttctttttt ctttgtcagt
     5701 tcatggattc tgaccaatgt accttcaaga ttgcgtgcat gtacggttgc aaaaacccgg
     5761 tgccctgtta gtgctgctct taccgcagca tgtgcagttg attcatctct tatctcgcca
     5821 atgattagca agtctggacg atgccgtaat gcgagtttca aaagtgtatc ataagtctgt
     5881 gctattttcg gattgatctg tagctgcaga aaaaacggtt cttctatctc tacaggatct
     5941 tcgatagtaa tcacttgcaa tttttcttcc aaagccaacc gatacattag agaagtcttg
     6001 cctgatccga ctggtccgct gaaaaggtat aatccacgtc tgacggtttt ctgtaaaata
     6061 gttgcaaaat ctcgagaact aaagcaacga tggggtgttt caaaagtacc gtataatagc
     6121 cgaatcacta aactctctcg ttgaaggtaa tctcctacag aagacaaccg cagacgaact
     6181 tcctgttttt ctaaagaata agtaaatgca cctaactgag cttttctttt ttctccgata
     6241 tccatctgtc ccaaatactt aaatcttgag atcagttgct gtccatctgc cgaagagact
     6301 ttcttccaga atgttcgttt ttttccatag cgaaaataga tgtaaaatac ttctgaagct
     6361 ggcaatatat atacgtcttg ggcatgtttg gcaaaacttt cacttatcat ttgatccgat
     6421 aatcgtttta tttccattat tctcccctcc acaaaaaaca tacgtctttt tgatcttttt
     6481 gtttcaaata aaatgaattt acaaaaaaat attggcaaaa gccgaattta tgttatactt
     6541 ataaaaattt atcttgggag gcactccatt ggaaacaaca ttaaggaaat atatcgaagt
     6601 agcaagtaaa aaaaagcctg ctgacctagt gatcaagcat gctaagatcg tcaacgtctt
     6661 tacgaaagaa atcatggaaa aagatgtagc aatctgcgaa ggaatgatcg taggaatcgg
     6721 tgaatacgaa ggaaaaagcg tacataatgc taatgggcaa tatctagtgc caggattcat
     6781 cgatggccat gtgcatatcg aaagctcact tttatcacca agcgaatttt caaaagtatc
     6841 cttgcttcat ggagttacta ctgtagtgac agatccccat gaaataggaa acattgctgg
     6901 gagtacaggt cttgagttta tgatagaaga tgcaagacaa acactcatga atatcttttt
     6961 tatgctacct tcttgtgtac ctgtaacccc ttttgagacc aatggtgcaa atttaaatgc
     7021 aaaaaaatta gccccttttt tacaaaaacc cgaagtttta ggcttagctg aagtcatgaa
     7081 ctatcaagca gtagcaaata atgaaacaga catcctagaa aagatccaat tgatgcacca
     7141 gcataagaaa aaaattgacg ggcatgcagc tggtatcggc atggaagagt taaatgttta
     7201 tcctgcagca ggtattcgga cggatcatga agctacaact gcaaaagaag ctaaagaacg
     7261 tttggatctt ggtatgtatt taatggttcg agaagggacc gttgcaaaag atctggcatc
     7321 gctactaccg gcgatcacac ctgaaaattc aagaagatgc ttctttgtca ccgatgataa
     7381 actgatcaat gatttagtaa aagaaggatc aatcgatcat atcgtccgtc aagctattgc
     7441 acttggaatc gatccattac aagccattca gatggcaaca ttgaatgcag cagaatgttt
     7501 tgatttgaaa acactaggtg cgattgcccc tgggtatcaa gctgatttct tcttaacaga
     7561 cgatcttacc aagctgccaa ttcatgaagt tttctataag ggaacattag ttgttcaatc
     7621 tgggcaactc caagaccatt tatttgctga tcattcaaat tcatatacgt gttgtctgcc
     7681 aaaactaaac gctcaaccat taaatccaca ttcgttagag ctgcttcttt cttcttcaca
     7741 agcccatgtg atcgaaatta tcccgaatag tctagtgact aaagatttgg tagaaaaagt
     7801 ggaccgacaa ggcgaacgat tcattccttc aatcgaaaaa gaccaattaa agattgcggt
     7861 gatcgagcgt caccatcaaa cgggaaacat tggattaggc atagtgaaag gatttcagct
     7921 gaaacaagga gcgatagcga caacgattgc ccatgactcg cataatctag ttgtcgttgg
     7981 gacaaacgac gaggatatgc tgtatgctgc taatcttttg attcaaaaag gtggcgggat
     8041 gaccgttgtc aacaaacagc aggaaatagc ttgtgtttct cttcctatag gcggaatcat
     8101 gacacaggaa cctttttcga tcgtctatga acagttgaat gaattaataa ctaaagcaca
     8161 tcaactagga gcagctaaaa cctttgatcc ttttttgaca ctttctttct taacattatc
     8221 tgtcataccc gaattgaaga tcaccgacaa aggattattt tcattttctc gcttccaatt
     8281 gattccacct tgtggaaaaa ccgatgaaat aaatacattt taaatcaaat aaatcccaga
     8341 aaatacatta catctgtaat gttcattttc tgagatttat ttatggatat taatgttttt
     8401 atgaaagcag aaagttagtt tcacagactt ttctttttgg tcttatcttg aaattgagct
     8461 tctactcgat aaatacgttg accttttgaa gaaaattttt cttcatactc cgtcataata
     8521 ttgccttcaa attgactttg atgtaaatct aaccatacct gtttgaggat catgccatat
     8581 tgagaaaaac ttgccagaga atactcaaac aatccttgat tatctgtttt gaaatggatt
     8641 tctccatttg gacgaagaat ctgttcatct acagcaagaa aagtcttata tgtcaatcgc
     8701 cgtttttcat gacgtttttt tggccatgga tcggaaaaat tcagatagat ttgatctact
     8761 tcgctgtcag cgaaatactc tgtcaacgct gatccatcca catgtagaag tttcaggtta
     8821 ggaagcggtt gttcgatcaa cttgtctagt gcaatcgaaa caacactgac ctgcatttct
     8881 actccaatat aattgatttc aggatgggct tttgccattc cagtgatgaa ctggcctttc
     8941 cccataccaa tctcaatgtg gattggatga tcgttttcaa acaattcatt ccattttccc
     9001 ttccacaatg ttggatcact aattacaaaa ttcgggtgag ccgctaacat ttccgctgct
     9061 cccggacgat ttcggacacg cattatttat ctccattcct ttcctctaat taaaaaggtc
     9121 tggccaaatc tccgcagagt ttgggccaaa cctcagccac tgaaaattcg ttttaattgt
     9181 aaaatttctt cgttcatccg tcgatgatct tcacgtttgc aatatctggt gatttcttgg
     9241 agcaaattca tggccgcata ccaatgaaat ttttcaagca tttcgtcagt cgggcgtatg
     9301 ccataactga tcagccactg attccagcta gacagtggca cataatttcc taaaatcgtt
     9361 gcaatatcca ccgcagggtc tgcaaacatg attgaatccc aatcgactag atataaataa
     9421 tttttacata ctaaccaatt acgatggttt acatctccgt gtactactga taagttttcc
     9481 ttatctattg acgggatctg ctcacgaaga aaacgatgga caatttgcag aaattgattt
     9541 ttctggagtt cttccggtaa ttctttttca tatttttgca gcatcttctc cggcgtcatg
     9601 acacgaccac cgatacgggt cagcatggtt ttaagagaat ttgaatgatg taaatggtac
     9661 aaaacatcaa tcacgtcgtt tctttgacca atctcattag gagtcagcaa gcgaccttcc
     9721 agccactctt gtgctgtcaa agtatcgcca ttccccgttc gttttgtcca aacaagtttt
     9781 ggtgtaattc cttcccttga aagagcagcc aacatcggag tcgtgtttcg tttaataaag
     9841 actttgtcct catcacgcat gcctatgtat gtttttcctg tgtcgccttt gatgggacgt
     9901 aaccgccact cttggtctaa ctgaaactcc atcatgcatt ctcccgtcct cttactcttt
     9961 gttttgcagt acttattatt ctagtcgcct gaacactaca cgtcaagcac atatacgttc
    10021 tttttcattt aattgccatt caaaaaacca gcttttctca aaaaaaatag aacgaacagc
    10081 attcttactg tcaacgctct atttttcatt ctcattttta ccctacacag ctttgttttc
    10141 agtctgacat cttcttcaaa cgagttggta catatagttt aacaaagagc atagtaacaa
    10201 tcaaataagc cgctagcgga acccatcgct gctgcccatc taatacgact gcagcaatca
    10261 aaccaaaaat aaccgacgcg ataattaata cccatgtgag tagatactga atcgcctgct
    10321 tcttctgatt cttatggatt ggataaagct gaacgagaac catatagcgg aactggttcg
    10381 ctaaaggtaa cagttggaaa ccgatcaaat ataaaaataa gaaaccgata atcagactaa
    10441 aataaaagtc gactactccg gcaatcaata acccacctat aattactaat cggaaataaa
    10501 gaccactaaa atcagaacct cttgctaatc ttcttgcaaa caagtaaaga taagtgtttt
    10561 ttgattctct tttaatatga gtcaatatag gatccaaata gcgtcttctt ttgatctttg
    10621 ccgtaatttc aggaacatct gtgaataaat tgataaattg atagatctga tgcaacctat
    10681 gttcttctac atgcaccatt ttctcccaat ccaatccttt ttcttgttgc ttccacaaaa
    10741 accagtaata tagacttgcc tgtactaatg cacctgctat tcctgcccat attagccaat
    10801 aaaatgatag aaacaaaaag atcagagaag aaaaaaacca gcctaatttc caataacgaa
    10861 taacttgttg atctagtcga aacaattctg ctctcttgat ttgcagatga ctgaatttca
    10921 aactccataa tatgatcaga tagacgaaaa acatcgaaaa ggattgctcc gtactaacca
    10981 ccactaatgg catggccaat ccgcatgcca atatcaaaaa gatcaacgga aaaatgcaag
    11041 aatagcgaaa agctcgttcc aaataggttt gcatttcttt ttctttagga agtaaaaaaa
    11101 caatatctgc tgcctctgca aaagtagcca tcttacccac gaataaacag agcatccaaa
    11161 atacagagat tatgagccct ccaattgcaa acggtggctg cagggttttc aaccaattag
    11221 aataatataa tcccacaccg ccaatcaaga aaagacaaac taaaacaaaa tgatcgttca
    11281 atacataacg catatatttc atcattttct tttgatgtct tgctaaacgt ttttgaaaaa
    11341 aactactcat gtgcctgctc ctttgttaaa gcaatataga tttcgtccaa agaagaatcc
    11401 ggcagctgaa attcttttct caacatctca agagaaccgt ctgctcgtat ctctccgtta
    11461 tgtaagacca caaaacgatc acaatatttt tctgcagtag ctaaaatatg cgtagacatc
    11521 aaaataccgg ctccttcttt tttcatttct accatcaatt caagcaatgc attgatagct
    11581 agtggatcca agcctaaaaa tggttcgtcg atgatatata aagaaggctc gatcaaaaag
    11641 gcgcataaga tcatcacttt ctgtttcatt ccctttgaaa aattagctgg gaaccagtca
    11701 agacgattag ataaccgaaa agtctccaac aacttttctg ctcttttcat tgctatatcc
    11761 ataggtatat cgtaggccat cgcagtgact tcgatatgtt ctctcaatgt caattcttca
    11821 tataaagaag gagtctctgg aatataccca atttgtttgc gatattcttc cgtatttttc
    11881 tttaaggata gatgattgat ttctatcgtt ccttttgaag cttccagcag accgataatg
    11941 tgcttgatgg tcgtactttt ccctgctccg ttcagtccaa tcaaccctac tatctctcca
    12001 ggctgtacat cgaaactgat atcttttaac acagggagat gtccgtaccc ccctgtgaca
    12061 tgatcgataa ttaaactcat tctttttcct ccgccattta tttttattta ttataccacg
    12121 aagaaaatga cggtattttg tttttttcct tacaatagct ttaacttatg gtaaagttaa
    12181 gctgaagtat ttattcttta tagaaaggat gttttatatg gaaaactgta ttttttgcaa
    12241 aatcatcaat caagaaatcc caagctataa aatatatgaa gacgacaagg tctatgcttt
    12301 tttagacatc tctcaagcaa cgaaaggaca cacattagtt gtgcctaaac gtcatgtagc
    12361 agatattttt gaatatgatc ccgaacttgc aggagaggtt ttttcgcgtg tgcctaagat
    12421 tgctcaagca ttggaaaaag cttttccaga aatgaaaggt cttaatatct tgaataacaa
    12481 ccgtgaacta gcctatcaat ctgtttttca ttcacatatc catttagtcc ctcgctacag
    12541 caaagaggat gatttttcta ttcactttgt caatcatcaa gatagttatg gatcggaaga
    12601 actaaaagct attcaagaaa caatcgtaaa gcaggtgtcc tgcgatgatt aaaaactttt
    12661 tcaaaggact gttatttgga gctgctgctg gcactgtcgg aggtctgtta ttggcgccca
    12721 ggagcgggaa tgaaacaaga aagaaactga tcgaagaatt ggaagaagca acaactctga
    12781 caaatgattt aaataacagc ctgaatcatt ttaaaagcgc attgatcgaa acaaaagaaa
    12841 cagctgaatc tgtgattcct gctttccaag aagcaatcaa aaaagatatc gaagatttta
    12901 aattccaagc cgaaccacgt atcacacaaa tcaatgaaca agtagaaaaa ctaaaagctg
    12961 atctgccaga gtatcctgaa caaatataat aatgattatt ttctcaacag atttaactat
    13021 ataagtgaga aaagtttgcg tatttcctag gaatgtgatg aaattttgaa ttttgtttga
    13081 aactaccacg acaacgtttt taaaggaaat gggatatggt atagttaata tataaaaata
    13141 ataactaatt acaggagtgc aaattttaat gaaaaaaaaa tcaattattt tggcagctac
    13201 tagtgcgttg gctgttttaa ctctagcagc ttgttcaggc gatactaata aagatatcgc
    13261 aacgatgaaa ggcggaacga tcactgtatc tgatttctat gatgaagcaa aacttgaatc
    13321 atcgaaccaa tccttagtac aacggatgat catttataaa gtattcaata acaaatatgg
    13381 cgataaagta accgataagc aagtggatgc agaatacgac aaacaagcga aatcattagg
    13441 tgatactttt gaatcacaat tagaagctgc tggatatacg aaagatactt ataaagaata
    13501 tattcgtaac aatttagctt ttgaagctgg cttgaaagct cacgtagata ttacagatga
    13561 cgatttgaaa actgcttgga aatctttcca tccagaagta gaagcacaaa tcatcaaatt
    13621 atcaagtgaa gatgaagcaa aagatgtgaa aaaatcagcg gatgatggag atgatttctc
    13681 taaattagcc aaagacaaat caactgatac agagacaaaa gaagatggcg gtaaagttaa
    13741 attcgactca acgacaacaa ctattcctgc agaagtaaaa gaagcagctt tcaaattgaa
    13801 agacggtgag atctccgatg ttattactac aacaaatcct acttcttatg cgacagaata
    13861 ctacgttgtc aaaatggtga aaaaccaaaa taaaggcaat gacatggata aatacaaaga
    13921 tcaactaaaa gatatcgcta ctgaaactaa actaagtgac aatgcattca caactaaagt
    13981 aatcggtgaa gaattaaaag atgcaaatgt aaaaatcaaa gatgatgcct ttgaaaatgt
    14041 gttgagtgca ttcacaacaa cttcatcaag tacgaaagac tcaagtgaaa ctacagcttc
    14101 aacaaagagt tctgacacaa aatcaactga ttcaacaaaa gaatcttcaa ctgaagaaac
    14161 aactgattca tcaaaataaa agaaaacaaa aaaagcgaag acttatgtct cgcttttttt
    14221 gttttgaatg aaaaaaataa atttttgcta taaatctttt ggtacataga aacttcggtt
    14281 gtccataccg aaaatccgat cggtgtattt tcctggttct gtttgacgaa tcgaagtcaa
    14341 catcatctgc atcgaagcat cgatattgtc gatttgatgt aatatttctg cttccattat
    14401 tcttggacgt acaggtgagc catattctaa taagccatgg tgtgctaaaa ccatatgacg
    14461 taatacaaga acatcttcgt cagcttcgct gattttcaac gcaagacagg ctttagttat
    14521 ttcttcgtca atcaatacca gatgaccgat caaatttcct gcaagcgtat attctgtcga
    14581 cataggaccg gaaagttcaa tcacctttcc taaatcatgc aaaatgatac cagcatacaa
    14641 caatgctcga ttcagctcag gatattcatc ggcgattgat ttccctaagt gaagcattgt
    14701 caaagtatga taagctaatc cactggcaaa tgcatgatgg tttctttttg ctgccggaaa
    14761 ctcaaaaaat tgtttttgat atttattaag tagatagcga acaatacgat tccaatgcgc
    14821 attggtgatc tcaaacaaca attgattgat ttcttcttcc atttcttctt tcttcaaagg
    14881 ggctctttcc atgtataaac taggctctcc tggctcatct acccttgtta agcgcatatg
    14941 aagaatcttt acttgagggt ttccttgata aacctctctt ttaccgttta gaaaaacgac
    15001 tgtgccggct gtaaatttat tgatttcctc ctccgaagca tcccagtatt taccatcgat
    15061 agtacctgaa gtatcttgga aagtaaaagc aataaatttt tttccgtttt tagcgattct
    15121 tacatctgca cttttgatca ggacaaattg ttcaaactgc tcatcgatta ctaaatcacg
    15181 aatttttttc attatttgct ccttctaatt gttttacgat ttggttcatc tcatggtaat
    15241 agcttaccat ttctttatca gaagaaaaac aaattatttg atacttttct ccaaatttag
    15301 ctaaaagttc agctaattga tactttcgct gatgatcata atgaagccag ccatcatcaa
    15361 tgatgatcgg gcatatcgaa cggttagctt ctaatgagag gtaagcaaat ctcatcgcca
    15421 taatcagctg atctttcgta cctgtagata actcatagat gggaaattct gtatatccgt
    15481 ctgttaaagt cagtgtatca tttttcagta atatcttctg ataatttcct tttgttaaaa
    15541 tacctaaata atcacctgct gctcttaaca actggggtaa ttgtctttca ctcatctctg
    15601 ttgaaagatc acctaagaat gtcccggcga tttcaagtgc tccccattcc tccagtaatt
    15661 cctgtaattt tgctttttgc cggctagctt gttgataaag ttcgtccaat gtgccgtctc
    15721 tttgcaactc ttctacttga agttggagtc gttgccgatt ttcacttgct tctttttctt
    15781 cttgctggag ttgggattgc ttttctttca gttggcgcag tcttacagat aatttctctt
    15841 ttgtcagctc ttcaggaaat agtggagtaa gcatttccga taattcattg tatcttttca
    15901 tctgctgttc ggcttgtttg gctttttgta aaaagacagg tacttccgaa ggataagata
    15961 agcctgcttg agtcaattgt tcgctgtatt cttgtatcca tactttttgt ttctttttca
    16021 attgattgat ttcttgcttc aataaagtat tttgctgata gcttctggca aatttcatct
    16081 gttccatctc ttgtttaaaa cgggaaagca ataccatttt ttctgaaatt gtcttatctt
    16141 gtatcggtaa ccattcttta acaaactcaa atttttggtc gatttgtcgt agtttttctt
    16201 gtatttcctg ttctctttta tgtttccgct caaatacgcc atataatttc tgataatcta
    16261 tgacttcctg tccatattct ttcatgagtt tgagcgtatc catctttcct aagtgccgat
    16321 gatccgcaaa acgatatact tcttgctgaa gaatctgttt ttcttctcca gttctctttt
    16381 gtttttcttc tgcttcagct aattgagcta aggctagatc aagttgtcct agtttttctt
    16441 gccacattcc ttttatctca gagaaatcat ttttagtttt aatttttggt tgccttttgt
    16501 agaagaaata gccaatcatg cctgcaccaa ttagtaaaag gatcactttc aagggcattg
    16561 gtacaaatat acctgcaatg attattgctc cgccagccat cagcatatac ggtttagatg
    16621 aagagactgg tgctatctct gactgatttt gtaataatgc tggataggtc tcttccaagt
    16681 cattcacttc tgcttcaatc atctcttgct gttctttagc tatttggaga cgcacagaaa
    16741 tctggctttc tagatcagca atccttcttt cttcagccag aagatgcttc cattcttctt
    16801 catataaaaa ttcttccggt aacggatttt tctgccaatg ccacctttgt tccaaaatct
    16861 tcaattctga atttgtttct ctagtctcaa tttgtaatct ttgccattct tcgtttaatt
    16921 gttccgctgt aaattgaagt tgctggagat cttttagttc ctgctcctgc tctaaataaa
    16981 aataatatct ggctgactgc tgatccatcc cgctatgctt ttccagtgtt gcttctaatt
    17041 cttccaaacg ctcatttgtt tgctgatacc gtttggagaa agactccaga tctaaaagaa
    17101 gttgctcatc aggaagacct gtagtgctgt tttttttgag agattgccat tcttcatata
    17161 aagaaaaatt aagttcttgc tgtctggcta atgaaaattg tttgttcgcc tcttttaatt
    17221 gtgccaataa ctgctgctgt tgcgactcgt attcctgttc ttgttggatc aacttgccaa
    17281 aataagcttc ctgttcttgt ttttgatgaa ttttttcttg cagctctttc cattcattta
    17341 atttttgatt gattagtaat ttttggcctt ttttcttgaa taattgttgt gctttctgat
    17401 aatattcttg ccgcttttgg aatacttgag aactgcccgt gatgcctaaa gaaatcagcg
    17461 catcatgtag ctctttttct ctcaaatgat ctagttccat caactgctct tgctggaaag
    17521 taaatacctg ctggaataac tctttcgtca aaggtgcgat cagtttttct agtaactcat
    17581 cacttcccac ttgatccccc agccacacct tcgattttcc gcgattttgc tgcttgtagc
    17641 gctcgacagc aaattcacca tatacaggat gtttaagcca tattttgccg ccataggctg
    17701 agccgtcttt tggtgtataa tccttttttt tacggccttt tgaagggaaa ccaaataata
    17761 ttgcttgaat aaattgataa atcgttgatt ttcctgcttc gtttccccca tagatcagct
    17821 gattgcctga ataaaagtca aaactttttt gacgccattt tccaaaagca gcaatctcga
    17881 tccttaaaat cttcattcct gatcctcctc aaataaaaaa tcttgattaa gcagctgctt
    17941 ggctttttca agtgtttctt cttgatattc cggcagttcg ctcaatattc tagccgcttc
    18001 ttgatgacta tatacttcat ttaaaatttg ttggaaatct tgaggtgtct gatagtattg
    18061 aaataactgt tccatcaatt tagcagaagc agcaagtggg gtcttcgtat aaaaagtatt
    18121 ctctatgaga gaaatacgcc aaataaagaa atcatttatc ctatctgaga attcctctaa
    18181 caaatagtct aatagctctc ctgattgtat ccgttccaaa acatctgtat tgagatggtc
    18241 ataatctttt aattttatct caattaaact aaatccatcc tctacttttg aaagctgctg
    18301 acgaatgtga acaatgacct cttttgtcgt tcttgctttc ctcaatgata tttcctttgt
    18361 cttccaatag acctctgcta ctttaatcgg atgtatttgg caacttcctt tacttaattc
    18421 aactagtaga atagatgtag aagcttgttc ctttttagta tgaccttgag gcgcacctgg
    18481 ataaacaatt gtttgctttt catttaagac cgttggcaca tggatatgcc ctaaagccca
    18541 ataatcgtat cccttttctt gcatctttga gggttggaaa ggagcatagt ttcctttttg
    18601 agagacgcca ggttccccgt ggtacaaccc aatatggtaa tctgtgagtt ctctagaagg
    18661 aaattccatc actttgtctt tttgaatcca cggttgacga taactaaatc cactgagaga
    18721 gacagtttct ccacttttta tcgttatttt ttttgtctct accgtttcgg atgtaaataa
    18781 atggacattt ttaggaaagg agaaccaata ccgctctttt tgatagaaat catgatttcc
    18841 gaatattata aatacaggta tatggttctt ttctaaccgt ttcatctgtt ctgaaaaatg
    18901 tttctgtatt tttaatgaag gacgattttg atgaaaatta tctcctgcaa gtaaaacaaa
    18961 atcaacgtta tttattattg cctgttcaat gatatttgat aaaacggtca gattcgtctt
    19021 caatagtttt tcctgtacag ttttatcaag agttgtcagt ccttcaaatg accgatccat
    19081 atgtaaatct gccgcatgga taaatttcac cattaaaaat ttcctccttt ttttctttta
    19141 tcataccatt ttcaatgttt tttttcatca ataaccgaaa atttgttcgt attatgcaaa
    19201 gaaattacga taaatggccg acttcaaaaa ataagtttat tcgaaaaaaa gattgtgaca
    19261 tgatttttgt cacaatccta aatatctatg ttatattcgc ttcgtttgac actgaagaag
    19321 tactatttgt actggaattt atgctccatt tttccgtatt tagaattcta tgttctatac
    19381 taccttaatt agtttatatg gtaagaattc tttcaaatgc ttgagatact ccgtctttat
    19441 catttgaaac agtgacataa tcagcttttt tcatgatttc ttgatgacta tttcccattg
    19501 caaaactaat atctgcactt tcaaacatag ataagtcatt taaactatct ccgatcgcga
    19561 ttctcaaagg tttctttaaa ttgtagattg attccaaacg atcaaacacc acacctttag
    19621 atacattttg aggtacgatt tcaatattta caggtgccga ttcagtaaca gacacattta
    19681 gcatcttttt caaatggtta aatatattag ctttcaattg acgattagga ataaaaataa
    19741 aaaatttgta aatgctgata gcatc
//
LOCUS       DADQCX010000053        19452 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.053, whole genome shotgun sequence.
ACCESSION   DADQCX010000053 DADQCX010000000
VERSION     DADQCX010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.053"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            128..3655
                     /locus_tag="J8R83_001720"
     CDS             128..3655
                     /locus_tag="J8R83_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAZ9574850.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3652..7374
                     /gene="addA"
                     /locus_tag="J8R83_001721"
     CDS             3652..7374
                     /gene="addA"
                     /locus_tag="J8R83_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAZ9574851.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7443..7784
                     /locus_tag="J8R83_001722"
     CDS             7443..7784
                     /locus_tag="J8R83_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574852.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8093..9136
                     /gene="pheS"
                     /locus_tag="J8R83_001723"
     CDS             8093..9136
                     /gene="pheS"
                     /locus_tag="J8R83_001723"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAZ9574853.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9141..11561
                     /locus_tag="J8R83_001724"
     CDS             9141..11561
                     /locus_tag="J8R83_001724"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAZ9574854.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11731..12741)
                     /gene="trpS"
                     /locus_tag="J8R83_001725"
     CDS             complement(11731..12741)
                     /gene="trpS"
                     /locus_tag="J8R83_001725"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAZ9574855.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12995..13732
                     /locus_tag="J8R83_001726"
     CDS             12995..13732
                     /locus_tag="J8R83_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574856.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13746..14561
                     /locus_tag="J8R83_001727"
     CDS             13746..14561
                     /locus_tag="J8R83_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAZ9574857.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14574..15221
                     /locus_tag="J8R83_001728"
     CDS             14574..15221
                     /locus_tag="J8R83_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9574858.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15237..15893
                     /locus_tag="J8R83_001729"
     CDS             15237..15893
                     /locus_tag="J8R83_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9574859.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16055..16876
                     /gene="racE"
                     /locus_tag="J8R83_001730"
     CDS             16055..16876
                     /gene="racE"
                     /locus_tag="J8R83_001730"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAZ9574860.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16879..18234
                     /gene="rph"
                     /locus_tag="J8R83_001731"
     CDS             16879..18234
                     /gene="rph"
                     /locus_tag="J8R83_001731"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAZ9574861.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18235..18753
                     /locus_tag="J8R83_001732"
     CDS             18235..18753
                     /locus_tag="J8R83_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAZ9574862.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18860..19360
                     /locus_tag="J8R83_001733"
     CDS             18860..19360
                     /locus_tag="J8R83_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9574863.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6540 a         3341 c         4178 g         5393 t
ORIGIN      
        1 gcgtatactt aaaaaagtag aaatatcaga accttaaaag gatataattt gaagaatata
       61 gaacaaatgt tcagtatttt ttgatataat aaaggagcac cgtatcatgt gttgaaggag
      121 gaaaagcatg tctttacaat ttattcttgg aaacgggaaa aaagatcacc gtcaagtctt
      181 gatcgacgaa gcatccgctt ggctcgacca ggatgcaagt aaccaagtat ttttccttgt
      241 tcccaactac agcaaattcg aacaggaaca agaaatttta gcggagatgc gaagaagaag
      301 cggaaaaaaa actttcagca caacaaacgt tcaagtattt agtttttatc gtctggcttg
      361 gtatttgctg caacagacaa ctcttcttac aggaaatgaa ttatcagaat caggatctgc
      421 aatgatcttg cgacagattt tagaaaaaaa tgaggaagaa ttaacaatct ttcgcggaga
      481 aatcaataaa agagggttta ttcgtcaatt acaagaactc tacagtgaat tgcgtacagg
      541 aaatattcaa ccagaagacc tgatgctttt atttggtgat tcacctaatg cagaagacca
      601 gcaacttaaa atgaaagact tgaagctgat tttttcagct tatgacagcg aattgactca
      661 acgtgcacta acaaatgaag atgcactatc tatactagca aattatatgc agacacaaga
      721 tttcaacaac gtcaaattta ttgtcagtgg tttttctcga atcaatggtc aagagtatca
      781 attactgcag gcaatgatgg aaaaggggca attggttgtc gatttattgc tggatcgtcc
      841 ttatacagcg gatcttccag aagtacttac gctctttcat gagactggaa agctttattt
      901 ccgtcttttt caaagtgcaa gagaacggaa agtccctata ttagtggacc gatttgcacc
      961 agagcagact cgtccgacag agcttcaact gctgcaaaca atgtgggaag agacatctag
     1021 ccaaaagaaa gcggcagtac acaaaatagg gggacaagag catctccatt tgtgggaagc
     1081 tgaaaatcca actgaagaag tccgacaatt agctgttgaa atcagacgac tagtcagtga
     1141 agaaaactac cgttatcgtg atatccaagt gctgacaaaa aatatgtctt tatatggaaa
     1201 tatccttcgg ccgatctttc aagaaatggc aattcctttt tatatcgatg aagaacaaat
     1261 gatggaaaat catccgctga tcgaatggat caacagtctg ttcgctcttg accgctattc
     1321 ttatcggcta agtgatatta tgcgtttttt caaaactgaa ttatttctgt cgacggaagc
     1381 agaaaccgaa cttgatgaat ggaaacaaga gcgagatgaa ttcaggaaaa aactggacat
     1441 cactgaaaat gtagcacttg cttacaatta tcaaggaact tattggactc gtgaaaaaga
     1501 ctggcagttt gtggcgtatg attttgaagc agaacagatt gaagacgtac agtatttgga
     1561 agaacagtca aatacgatta gacgattatt tcagaaagct gtaccagtat ttttgaaaaa
     1621 aataaagaaa agcaaaacag gacaagaggc cgcaaatgtt ttttatcaat ttttgatcca
     1681 aagtggcgta cagcaacaat tattgttttg gcgtaatcag gaagtagaca gaggaaactt
     1741 agaagcggca agaaaccatg agcagacatg gggagcgctg attgatctgt tggatgaata
     1801 tgtagtaatt tatggtgaat cggcttttga ctggtcactg ttccaagaaa tcattacaag
     1861 tggtctagaa aatctaagtt atggtaaaat ccctaccgca atcgaccaag tgcgaatcaa
     1921 tcgtttggaa ttagttcgac caaatcaagc tgccgtcact tttgcattag ggttgaatga
     1981 tcaagtgttt ccagaccgaa aagagacaaa aggattgttg tccagtgaag aacgagaagt
     2041 attaaatcag gccttgccag atggacagtt tttattcgac ccatcaaagg aaagtatctc
     2101 ttttgagcct ttccaagcct atcttgtttt tctttccgga acagatcgat tatatcttag
     2161 ttatgcacaa agctatgaca cagatggttc gctgaagatg tctccttatt tgcgtagaat
     2221 cacagaatat ttatctgttc ccgtcgagag aaaagagcat ttgacgatcg aaagcgaccc
     2281 taattgttat gtagggactt acagaagcgg aatcaataca gtcaatagga tttatcgatt
     2341 agctttagat gaaaaaaaac ctgtaccaaa gcactggcaa aagctcaaag aattagtact
     2401 gaattcgtca tggcgaaatt ttgctttaca gatttttgaa agtcaggaac atttaaatgt
     2461 tcctgtttcg atgccagaaa aaatggcgga agagctttat ggaaaagaga tttatacttc
     2521 aatttcacgt atggagaatt tttataattg tgaatacaaa tacttcatgc aatttggttt
     2581 gaaattgaaa gaacgaactg tttatggtct aactccagca gcaactggtg atttttatca
     2641 tgaatcattg gatcgtttct tcaagctact gttttcaaac caattatcct tagtgaatat
     2701 gtccgatgcg cagcgtagag actttactga aaaagtgctg caggaagtat tcggagaact
     2761 tcggtttgag atattggata gttctgcaag aatgaactat atccgctacc agttaggaca
     2821 gacgattcaa aaagtgacat gggctttgca aaaacagagc aaaaatacag gcatgcatcc
     2881 tcttcagaca gagattctat ttggtcagat tgctggagca aaaggtatca caggtctgga
     2941 attaccgttg agtaatggtg gaaaactcca tgttcgaggg aaaatcgatc gaatcgatgt
     3001 agcttctgaa caagaagata cttggctaag cgtcgttgat tacaaatcta gcggacgttc
     3061 attcgatgtc acagaagctt attatggcat ggctatgcaa ttattgacgt atctggacgt
     3121 agcattgatg gatgcggtac gtttgactgg aaaggcggct gttaaaccag caggatcata
     3181 ttatttacat gttcataatc ctgtattgac ggagacagat gatgtagaga agaatacatt
     3241 gaaaaaattt agttatgatg gcgtttttgt cgatgatccc gctcttttag aagtactaga
     3301 tcattcactg gaagcaaaag aacaatcact gatctatcca gtgaaaaaaa atgcgaaaga
     3361 tgaataccaa aaaggtagtt tcagtaaaga caaatttttc acggaagaag aactgcaact
     3421 attcatggcg cataatcggg aaaatatgcg gttagctgga gatgcgatta cttccggaga
     3481 aatcaaacta aatccagctt ataaagataa acagcggatt gcctgcgaat tttgtccatt
     3541 cagaagcatc tgtacgtttg atgtgatgct gaaagaaaat aattaccacc gtctggagaa
     3601 aatagataag gaagaagcac tgcgtagaat attgaaaagg agtgaagaag agtgaatcaa
     3661 attcctttaa aaccgcaaaa tgaacgattc acagatgatc agtggcaagc gatttttgat
     3721 caaggagata atctattagt ctctgcgtct gccggatcag gtaaaactac agtgcttgtt
     3781 cgaagagtga ttgaaaaact aaaaatgggt tttgatatcg atgaattatt gattgtgaca
     3841 tttactgaag ctgccgcaag agaaatgaaa gaaagaattc aagaggcatt acaagaatcc
     3901 gtcaatagcg aaagtgaccc tgtacgtaga cagcatttta ctaagcagtt agttttattg
     3961 cccacagcga atatctcaac cttacatgct ttttgcctga cagttattcg acgttattat
     4021 tacttaattg atattgatcc agtctttcgc atgttaacag atgaaacaga aacgatcttg
     4081 atgaaggagg atgtgtggga cgagctgaga gaagcacttt atgcagaaaa tgatgaacga
     4141 tttttccaat taacaatgaa tttttctaat gatcgttcag atgacggctt gacgaatctg
     4201 gtgttttctc tttatgagtt tgcccgtgcc aaccctgacc cccaaaaatg gctagaacag
     4261 ttaagcgata attatcgttt gcctgagggg ctagcgaaat ctcgattata tcaaaaacaa
     4321 atccgtcctt tagttttggc agatatatac caatgtgtac agttatatga acagatgact
     4381 cagttagcac aaggtgaagg attagaaaaa atgcatgagc aagtagctgg agaacaacag
     4441 cagatcaaga atatctatga agcgttctcg caagatcggt tagaagaagc ttatgctggt
     4501 ttggaacaac taactttttc aacttttaag agcagtcgga aagcagaatt gaaagaaatt
     4561 tccaatgaag tcaagggcat gagggataaa gcaaaaaaac tgattcagca gataagtaaa
     4621 agttattttc ctgtttcccc aagccaaatg gaagaattaa cggacaaagc actaccgtta
     4681 gtcgaagaaa tgacaaaagt cacgcaaagc ttcatggacg gtttcagtat gcgtaaacgg
     4741 gaaaaaggtg tgctggattt caatgatctg gaacatttag cgttgcagat tctcacagaa
     4801 aaaacgaaag atgtatggct gccaagtgaa gcttcaaaac attatcgaaa aaaattcaaa
     4861 gaagtaatgg tagatgaata tcaagacgtg aaccaattac aagaagccat tttatactgg
     4921 ctaagagaac ccgatgatac aaaaggaaat atgttcatgg ttggggatgt caaacaatcc
     4981 atctattctt tccgtttagc agatcctagt ttatttatcg ggaaatacga gaatttctca
     5041 aagaaagaag gcggacgtcg aatcgttttg gctgagaact tccgctctag aaaagaagtc
     5101 ctttctttta cgaatcttat ttttgaacaa ctaatggatc cagcagtggg tcaaatcaat
     5161 tatgacgaag cagccaaact gatccaagga ttttcagact ttccagagaa tgaacagttt
     5221 gagccggaaa tcatgatcta tgaaaaagaa caggaagaat cagagattga gattccgacg
     5281 gatgatatac tggaagacaa aacagaaggc gaacttttta tgacaggact aaaaattcgt
     5341 caattaattg attcctcctt tatgatttat gataaaaaat caaaaaaaag tcgtccgata
     5401 gagtacaaag acattgttct cttgacacct acaaagaaga acaacttaac gattttagag
     5461 attttcaaaa cattggatat tccattagag atgaatgatg ctcaaaacta ttttcaagcg
     5521 acagaaattc gcacgatgat ctcgctgcta caattaatcg ataatcccta tcaagatatt
     5581 ccgcttgcgg ctgtattgcg ctcaccgatc gtgggtctga ttgaaccaga attagccagc
     5641 attcgattag ctaaccgtgc acatacttac tatgatgctg tgcttgctta tcaagcatca
     5701 aacgaagatg aattagcagc taagctggaa cattttggca agcaactaga gcattggcga
     5761 gaacttgctc gccgttcttc gatcactgac ttgttatggg atatctatta tgagacggga
     5821 tatctagagt atgtggtcgg tctgccagca ggggcacaga gacaagccaa tctttatgca
     5881 ttggttgatc gtgccaaagc ttacgagcaa agttctttca gaggattata ccagttcgtg
     5941 cgtttcattg aaaaaatgca agaaaaagat aaagacttag cagaaccagt catttcaata
     6001 gaagataatg ctgttcgcgt tatgacgatc catgcaagta aaggcttgga attcccagtt
     6061 gtatttttgt tagatatgac aaaggagttc aacttacaag acttgcgcaa tcggtatgct
     6121 tttgaagaaa aacttggagc aggaattcgc tatatggatc ctgaaacacg agtgttatat
     6181 gatacgttac cgtttcaagc catcaaattg gcaaagcaaa acaaattgtt gtcggaagaa
     6241 atgcgtaaat tgtatgtagg attgactcgg gcagaacaaa agcttttcat tgtcggttcc
     6301 tataaaaata aagagcaaat gatccaaacg tggtctgaag cagctgatca tgaggagtta
     6361 gtttttgatc ctgcgctacg tttgaagggc agaagcagct tgatgaattg gattggttac
     6421 ggattgatcc gtcatcctga aatgcagaaa tacttagagg aagaaatttc gacttctctt
     6481 cttcaacatt caaatgcaca gttttctatt tcatggatga atcagcaatc gatcattgaa
     6541 caaagacagt tgcttgctga aaaagaactg gttaacttag atcagcagat gaaagaagat
     6601 gaaactttat tagcagattc gttacaaaaa cgtctggcat atgaatatcc ttatcaagct
     6661 tcttcacaaa ccacaagtta tcaatctgta tctgaaatca aacgattatt cgaagatcca
     6721 gatgatacac aagaatcacg tttgactctg gaaagcagtc agaacaaagc agcatcccgt
     6781 caatttcgtt atacgcaaga acaactagca gaaccaaaat ttttgcaaaa agatcggcaa
     6841 gtgtcagcag ctgctgttgg aactgctacg catgctttgt tacaattact gccattagag
     6901 atgccaacta cagagagtat ccatcaaaaa ttacaggaat tggtaaggaa acggttagta
     6961 gacgaaaaag tcgcgaaaaa agtagatgtt tcttctatta tatggttctt tcaaacagaa
     7021 cttggtcaac agctgattgc caacaaagaa aacgtaaaac gagaacaacc tttttccatg
     7081 ctgcttcctg ctgacgaagt atttcaagac tatccaaatc aagaagatga actattaatc
     7141 cacggaatcg tcgatggata cctagaagaa aaagatcatc tcaatatcta tgattttaaa
     7201 acagatttta ttttacatcc ggatgatcca gcagaaatag atgcaatcgt ccaaaaatat
     7261 caaggacagc taagacttta ccaacaagca atgtcagaag ctttgaataa gccagtagaa
     7321 aatgttttcc taattttgct tcgagtgaaa caaattataa acattaacaa ataattataa
     7381 ttgagcaaac ttgacttatg ttttgtaagg attatgctat actctgggaa gaggtgagta
     7441 tgatggagct aacacagaca gaattcgttt tatgccctaa atttgaaaaa acattctcta
     7501 ttttaggaaa aaaatggaac ggattgatta tcgatgtact actcgaaaac ggtccgcaac
     7561 gctttgttga gcttgcggca aaaatcccga tggtcagtga tcgagtatta gtcgaacgct
     7621 tgaaggaatt agaaaaagaa ggaatagtca ctcgaaactt tgcctgtagc gaaaagagcc
     7681 gttcagaata tctcttgact gaaaaaggag cagacttgca aaaagcgatg cgtcaaatac
     7741 aagtttggag cgaaaaatgg atcacagagg aagaatgcgg ttgattttgt aaaaaaaatc
     7801 ttgtaaacta tagtccatac gaataagtaa agaacgatga cgaaaaagag tagtttggct
     7861 aaaccagttc agggagatct gtcgcagact gaaagcagat cctgtgtttg aaaaatgaag
     7921 ttcactttcc gagttcgtct gataaaatca gaccggcaat tgtcgttaac gaagtaagag
     7981 tgcggtgtaa gtcatttatc cgcaaattag gatggtaacg cgaagacctc gttccttaac
     8041 aggaatgagg tctttttgtt ttgtatttgg aatttaaagg aggaacaagc acatgtctct
     8101 acaagcacaa ttagagagct tgaaagaagc aacgctcgtc aaaatcacag cggcacaaga
     8161 tttaaatgaa ttaaatcaaa tacgtgttga aacgttagga aaaaaaggac cgatcacaga
     8221 agtattacgt gggatgaaag atctaagtcc agaagagcga ccaaaagtcg gaagtttcgc
     8281 aaatgagatc cgagatcttt tgacagaaga gatcgtgcga aaaaaacaag tattagaaga
     8341 agaagcgtta aatgcagctt tggcaaaaga aacaatagac gtgacactac ctggtagaaa
     8401 agtaaaacat ggtacacgtc atatcgtgac acaaatcatg gaagaaattg aagatatttt
     8461 tgtgggtatg ggctatcaga tcgtagaagg atatgaagta gaatctgatc attacaattt
     8521 cgaacggatg aatctgccaa aagatcatcc agcaagggac atgcaagata ctttctatat
     8581 ttcagacgag atattgattc ggacacatac ttcaccagtc caagcacgga caatggaaaa
     8641 acatgatttc tctaagggtg ctctacgaat gatctcgcca gggaaagtct tccgcagaga
     8701 tacagatgat gcgacccaca gtcatcagtt ccatcaaatt gaagggctag ttgttgataa
     8761 aaacatcaca atgggcgacc ttaaaggaac attagaagtc gtaatgaaaa aaatgtttgg
     8821 ggaagatcgt gaaattcgtt tgcgtccaag ttatttccca tttacggaac catcagtaga
     8881 agtagatgtc agctgtttca aatgtggtgg tgccggttgt aacgtatgta aatacactgg
     8941 atggatcgaa attttaggag ctggcatggt acacccgaat gtgttgaaga tgtcaggaat
     9001 cgatccagaa gaatattcag gctttgcttt cggccttgga ccagaccgcg tagctatgtt
     9061 gcggtatgga gtgaatgata tccgtaattt ctatcaaaat gacttacgtt tcttaagtca
     9121 gttcaagggg gagtaagaaa atgttagttt catataaatg gctcaatcgt tatgtagatt
     9181 tatcgaatgt aacaccaaaa gaattagcgg ataagatgtc tgtgacagga atcgaagtag
     9241 agggagtaac ggttccagaa gaaggcttga aaaaaatcgt tgtcggtgaa gtcaaggaat
     9301 gcgtaccaca tccagattct gatcaccttt ctatttgtca agtcgatatt ggcgaagacg
     9361 aactgtctca aatcgtttgt ggagcgccta atgtgaaggt tggaatcaaa gtgattgttg
     9421 cacttcctaa ctcacgtatc gctggtaatg taaaaatcaa aaaaggaaaa atgcgtggcc
     9481 aagtatcaaa tggcatgatt tgctcattac aagaaattgg ctattcagat agtgttatac
     9541 cgaaagaata cgctgaaggt atctattata tgccacaaga agctgtaaat ggcgatccag
     9601 tttttcctta tttggatatg gatgattcga ttattgaatt atctatcaca ccgaatcgtg
     9661 cggatgcatt gtcaatgcgt ggcgtagctt atgaagttgg ggcaatttat cgtcagactc
     9721 ctacattcga tgacgaaaag ctggtagaat cctcacgtcc tgctagcgat aaaattcaag
     9781 tggaagttga agataaagaa gcagttcctg cttatcaaat cagaatcatt gaaggagtaa
     9841 gaatccagcc aagtcctcaa tggctgcaaa atcttttgat gaacgaaggc attcgtccaa
     9901 tcaacaatgt agtagatgtg acgaactata ttttgctttt attcggacaa ccactacatg
     9961 catttgacta cgacaaattg aaatcaaaag agatctttgt ccgccgtgca aaagaaaatg
    10021 aaacattagt aacactagat ggagaatctc gggaattgac aactgacaat ctcgtcatta
    10081 ctaacggcaa agaaccagtt gctttagctg gtgtcatggg agggttagac tcagagatca
    10141 cgaatgaaac aacaacagtt gcactagaat ctgctttatt tgatccaatt tcgattcgtc
    10201 gtacagcaaa acaatttaat ttgcgtagtg aatcctctgc acgttttgaa aaaggaatca
    10261 accatgcgac tgttggagaa gccagtgagg ttgctgcagc aatgatcgtt tctcttgcgg
    10321 gtggggaagt tctacaaggc gcggtcaaag gctcagagat caaagcagaa gacgtatcag
    10381 tgaagatttc acttgaacgc atcaatcaat atttaggaac atctcttgtc gttaaagaag
    10441 taaatgagat ttttgaagca cttggattta gctatgaaga aaaggagtat gtttattccg
    10501 tagtagtacc accaagacgc tgggatatcc aaatcgaagc agatattatc gaagaagttg
    10561 ctcgtattta tggatacgac cagttgccat ctacacttcc aagtggagaa acggttgctg
    10621 gaagcttgtc aaaagaacaa gaaactactc gtaaaattcg tacaatcttt gaaggaagcg
    10681 gattgagcga agcaatcagt tatgcattga caacagaaga aaaatcaaga cagtttgtta
    10741 taaatgaaag taatattaca cgtttggact ggccaatgag cgaagaacgt tctgtattac
    10801 gaatgaattt gatcagcgga ctattagatg atatcagtta taacactgcc cgaaaaaata
    10861 cagagattgc tttatatgaa attggtcggg tgttcttcca agaaaatgat ccacgtacac
    10921 atctgccgca agaagtaaaa catgcagcaa tcgctatttc tggtatttgg gaagaaaaag
    10981 attggcagac gaaagctcaa aatgtagact ttttcaccat caagggtctt ttagaaaact
    11041 tatttgaaca actaggcatc actgaagatg tccattatca aacagtgaca gaaatgaagg
    11101 aaatgcatcc tggaagaact gctgcgattt accttggcga aaaatttatt ggttttgtcg
    11161 gtcaagtgca tccaacgatt acaaaaagtt atgatattcc agaaacatat gttgctgagt
    11221 ttgatttatc tgctatagtg gaagctgctc aaaaagggat cgttttcgaa gcagtgacaa
    11281 aattcccagc agtcagccgg gacatcgctt tgcttgtaaa agaaactgtg acaaatcagg
    11341 aattaacaga agttatccgt tctgctgccg gaagattttt aacagatatc caattatttg
    11401 atgtctatca aggagaaaac attgaaaaag gacataaatc catggcgtat agcctgacat
    11461 tcgtcaaccc agaagcaaca ttgacagatg aagaaatcaa taaagcaatg gaaaaagtcg
    11521 aaaaagcgtt ggtagaaaac ctagaggcaa gtattcgcta agaaggaaaa tatagtaagt
    11581 aacgatcaag tagcttttga agaccataca tttgaaaaaa agatgtgaca caacttcgtc
    11641 acatctcttt ttttgatttt aaaaaaggaa tagcacagag acgagataaa aaaacaggcc
    11701 tttacagcct gcttttttag agtaaatgaa ttaatggaag taattgattc ccattgctga
    11761 ttttacttca gaaagtgttt gtgcagctac tttagcagct tcttcactac ctttacgtaa
    11821 gatttccata acagctgaag gatctttttc caattcttct cggcgcgcac ggatcggtgc
    11881 aaattcagct tccaatacat caatgaggta tcgtttgatc tttacatcac caagtccgcc
    11941 gcggcggtaa tgagctttca tttcttcaat tgcttcttta tctgttccga atacatccaa
    12001 gtaggtgaag accatattcc cttctacttg tccaggatct tgtacatgga tgtggtttgg
    12061 atcagtatac atactcatga cttttttctg taagacatcg gcaggatcgg agatataaat
    12121 accgtttcct aacgatttac tcattttgcc atttccatcg attccaggta atctacccat
    12181 tccttttggt gggaatacgc cttttggttc caccaagact tcaccatatg tatgattgaa
    12241 gctttgtacg atttcctgtg tctgctctag cattggtttt tgatcctcac caacaggtac
    12301 aagattcgct ttgaatgcag tgatatctgc tgcttgagaa acaggataga taaagaatcc
    12361 tgtaggcacg ctttcaccga attttttttg ttcgatttct gttttgacag tcggattgcg
    12421 ccgaacgcgt cctacgctga ctaagttcaa ataatacatg gttaattcag ctaattccgg
    12481 aatttgtgat tggataaata aagtagattt tgcaggatct aatcccacgg ctaaatagtc
    12541 taaagcaact tgcaagacat ttgatgaaac cttctcagga tttttagcat tatctgtcag
    12601 tgcttgcatg tcagcaatca tgacaaacag ttggttgtct tcatctgcct gcatagccac
    12661 tcgggttttt agagaaccga cgtaatgccc taaatgcagc ttcccagttg gtcgatctcc
    12721 cgttaaaata atatttttca aaaaagacac ctctttacga tttgtaagtc tgagcactta
    12781 atatcttacc gtttttcctg aaaagaaaca acagttccta aggaaaaaac aaggaaagag
    12841 gataaaataa ctaatagatt agaaatggaa gaaatattta tgggagaata aacgttctaa
    12901 gaaactttac aaattactaa actatcagat ataatgtatt ttattataca tctttaaaag
    12961 aaatcttact aaataataat gggagtgtaa ttctatggca atgattaaat ttgatcacgt
    13021 ggataaatat tatggcaagt tccacgcatt aaaaaatatc aatctcgaat tcgagaaagg
    13081 agaagttgtc gttgtcattg gtccttctgg ttcaggaaag agcacgatgc ttcgctgtat
    13141 caatggatta gagacgatct cttcaggtaa gctgctgatt aatgatactg acttgcatga
    13201 taaaaagaca aaactgacag aagtccgaaa aaacatcggc atggttttcc aacatttcaa
    13261 tttgtaccca aataaaactg ttctggaaaa catcaaatta gcaccaatca aagtgttgaa
    13321 gcaagaccag gcaactgcag tcaaaaacgc ggagaaattt ttgaaaactg tcaatatgtt
    13381 agataagaaa gattcttatc cttccatgtt atccggggga caacagcaac gggtggcaat
    13441 cgccagaggt ttagcgatga atcctgagat gctgctgttt gatgaaccta cttctgcttt
    13501 ggatccggaa atgattggtg atgtattaga cgttatgaaa aaattggctc atgacggtat
    13561 gtcaatgatt gtcgtgacac atgaaatggg ctttgccaaa gaagtggcgg atcgtgttat
    13621 cttcatggct gatggagaag tattggaaga cagcagaaat gtgagagact ttttcgaaaa
    13681 tccaaatgaa gtccgagcac agcaatttat cagtaaagtt atcaatcatt gataggagga
    13741 aaaagatgcg caggttaaaa aaaatacgcc tgattttcct tttaggcatt gcttttcttg
    13801 cactagccgg atgtaaagga aatgggttgg caaatgaaga tattttagag cgaagcaaat
    13861 ctaccaatga aatcatctgg ggtgtcaagt atgatactcg attatttgga atgatggata
    13921 ttgagagcag aactgtacaa ggatttgatg tagatattgc aaaagcaatc actaaaaaga
    13981 tccttggtga caatggaaaa acagaatttg ttgaagtcac ttctaaaact cggattccat
    14041 tattgaaaaa cggaaatatc gatgcaatta ttgcaacgat gacgatcaca gatgaacgaa
    14101 aaaaacaggt tgacttttca gatgtctatt tcgatgctgg ccaagctttg ttggtaaaga
    14161 aaggaagcca aatcaaaagt gtagatgatt tgaatgcttc tacaacggtt ctagcagtca
    14221 aaggttctac atcggctgcg aatatccgac agcatgcacc agatgcaaaa attttagaat
    14281 tagaaaacta tgcagaagca tttactgctt tacaatctgg tcagggagac gcgatgacta
    14341 cggataatgc gattttgtta gggattgcag atgaaaatcc agagtatgag ttagttggtg
    14401 gaacgtttac taatgagcct tacgggattg cgatcaacaa agggcaagaa aacttcttga
    14461 aagctgttaa ccaagcgcta gaggaaatgc atgcagatgg cacatacgat aaaatctatc
    14521 aaaaatggtt tccaaatgaa actgaaggaa aagtagagta agggggagag gcaatgagcg
    14581 aattgataca aacttatgga ccaatctttg tcgacgggtt caagatcaca ttgttttcga
    14641 gtgtcttagc acttgtgttt agtttgatta tcggaacgtt aatggcaatc ttccaattat
    14701 caaagaataa agtagtgagc gccttagcaa aggcatatgt agaatttttt agaaacattc
    14761 cattattaat catcgtgatg tttttttatg ttgtcgtacc gatttattgg tttaatctag
    14821 atggattcca agcaggtacg attggattaa cgatctatac atctgctttt attgctgaaa
    14881 cagtacgttc agggattcaa accgtaccaa aaggtcaaac agaagcagga ctatcttctg
    14941 gttttaccta ttcagaaatc atgcgttata ttgttttacc gcaagcattc aaaatcgtta
    15001 tcccgccatt aggcaaccaa tttatcaacc tcgtaaaaaa ctcatctatt ttagcaatcg
    15061 tagctggttt agatttgatg tatcaaggag acttgatcgc tagtgaaaca ttcaatacct
    15121 tcgatacgta tatcatcgtt gggttatttt acttagttat cacgctaccg ttatcttact
    15181 taatggttta tcttgagaaa aaatgggcgg ttcgttcata gaaggagggg aaatacatgg
    15241 attttagcgg cgctttttca tggatgaata tccgtttttt attggaagga ttaaaggtta
    15301 ctgttgaagt ttcattgttt tcgatcattt ttagtttctt gatcggtggt ctgacaggtg
    15361 tgattcgttt tgcgaatatc cctttctttt ccaaaatcct tggtgtagtg attgatatta
    15421 tacggaatct tccattatta ttgatcattt tcttcactta ctttgcctta cctcaaatcg
    15481 gcattcagat gaacatcttc tggtccgctg tcgcagcatt aacgattttt gagtcagcta
    15541 tgttgtcgga aattttccga gctggactca atgctgttcc aaaaggacag atggaagcag
    15601 gattatcaac gggactgact tatgtagaat cgatgcgaac gatcgtgtta ccgcaagcat
    15661 ttaaatcaat gatcccggca attgtgagcc aattgatttc actgatcaaa gatacttcat
    15721 tagcagtaat catttcttta cctgaacttt ctcatcaggc acgtattatt tatggacaga
    15781 acaccaatta tgtgcttccg atgttcatca tcatgacact tatgtacttc gtggtatgtt
    15841 acgcgctttc tctgctttcc ggttacttgg aaaagagacg gtacagttat taatagatga
    15901 ttcttttagc ggttgtggca aactaaagtc acaaccgctt ttcctctttc cattcgaaaa
    15961 aaagagattt cgattgtttt aagcaagtaa gagcacttga aaattcacgc taaaaagtac
    16021 acaataggga ggatagaatt tattgaaaaa aaggatgata cgattgacag ataatcgccc
    16081 tatcggattt attgattcag gtgtcggcgg cttgactgta gtaaaagaag ccctgaaaca
    16141 attaccgaat gaaaatattt tatttgtagg agacacagca cgctgcccat atggccctag
    16201 acccgcggaa caggtaatcc agtatacttg ggaaatgacg gattatctgg tggagcaagg
    16261 aatcaagatg ctggtgatcg cctgcaatac cgcaactgcg gtggctttag aagaaatcaa
    16321 agctgctctt tctattccag tcatcggtgt gatccttccc ggtactagag cggcagtaaa
    16381 aaaaacacaa aataaacaag ttggcattat cggtacgatt ggtacggtaa aaagtcaagc
    16441 ttatgaaaaa gcactgaaag agaaagtacc agaattgact gtgacaagtc ttgcttgtcc
    16501 caaatttgtt tcagttgtcg aaagtaatga ataccattca tcggtggcga aaaaaattgt
    16561 ggcagaaaca ttagctcctt taaccactaa aaaaatcgat acattgattt tgggatgcac
    16621 ccattatcca ttattacgcc ccatcattca aaatgtaatg ggagaaaatg ttcaactgat
    16681 cgattctgga gcagaaacag taggtgaagt atctatgctg ttagattatt tcaatttgag
    16741 caattcaccg caaaatggtc ggacattatg ccagttttat acaactggct ctgccaaact
    16801 tttcgaggaa atagctgaag actggcttgg aatcggacac ttaaatgtag aacatatcga
    16861 attgggagga aaataaggat gcgtcatgac gggagaaaag cccaagagct tcgcaaactg
    16921 gagcttcaaa caaatgtttt caaatatcca gaaggatcgg tagtgatccg ttttggtgat
    16981 acaacagtta tttgttctgc aacaatagaa aattctgttc cccctttttt gagagaaaca
    17041 ggaacaggat gggtgacagc agaatatagt atgctgcctc gagcaacgag tacgagaaat
    17101 cgtagagaaa gcagcaaagg gaaactttct ggtagaacaa tggaaatcca gcgtcttatt
    17161 ggtcgttcct tgcgtgcagt agtagacttg gaaaaattag gagaacgtag tatcatcgta
    17221 gactgcgatg tgatccaagc ggatggcggt actagaacag caagtatcac tggggcattt
    17281 gtggcattga aattagccat tgaaaaactt ttaagagaaa aagaattgtc agaagatcca
    17341 ataaaagaac atcttgctgc agttagcgta ggaatcttac cagatgggac ttgcgtcaca
    17401 gatttggatt accaagaaga ttccgcagca cttgtagaca tgaatcttgt aatgacagaa
    17461 tctggaaaat tcgtggagat tcaaggaact ggagaagaag caacgtttga tggtgaacag
    17521 ttgaatgaaa tgctcttttt tggaaaaaac gcgattgaag atttgatcaa agagcaaaaa
    17581 catgctttgc taacagagtt tgctcaaaat gatgagcgga tagaagaaac aaaaacaatc
    17641 atcattgcga caagaaatcc aggaaaagca gaagagtttc gaaatatgtt caaagaagcg
    17701 ggatatcatg taaaaacatt acttgactat cctgaattgc cagatgtgga agaaactggc
    17761 agcacatttg aagaaaatgc ccgattaaaa gcagaaacga ttgcacaatt gcttgatcag
    17821 ccagtcttag cagatgattc aggtttgaaa gtggatgctt taggcggtat gccaggaatc
    17881 tattctgcac gttttgcagg ggaacaaaaa agtgatgcgg ggaataacgc caaattatta
    17941 tatgaattga cagatgtgcc ggatgaaaaa agaacagcac aattccattg tacgttagta
    18001 ttcgcggcac ccaaaaaaga cagccttgta gtagaagcgg aatggcccgg tcgagtagcc
    18061 cgtataccat ctggcgaaaa tggctttggg tatgatcctt tatttatccc agaaggtaag
    18121 aaacaaacag cagcagaatt atcgagcgaa gaaaaaaaca agatcagtca tcgggctcaa
    18181 gcaatgaaaa aattgagtgc cgagtggaaa caatggctgg aaggagagag atagatgcgg
    18241 tatttagtag taagtgataa tcatggagac agagatatcc tcgttgactt agtagatcgt
    18301 tatcgttctg aagtggatat ctttttccat tgtggtgatt cggaattaga agcttctgac
    18361 ccattatggg atacattcca agtggttcaa ggtaattgtg attatggacc aggattcgaa
    18421 cagaaaaaag tgatccaaac tggtcaggat acagtattca tgactcacgg tcatttatcg
    18481 aatgtccgat ttggtttgac acagttagca atcgaagctc gagctgcaac tgccgatatg
    18541 gtgttttttg gtcataccca tcaaataggc tgtgagatgg atcagaaaat cctgtttttg
    18601 aatcctggta gcatttctca gcctagaggc ccgatccaaa tcccatcata tgctcttatc
    18661 gaaagtttag atgaccaaat ttctgttcaa tactataacc gtgcccatca ggcagttgaa
    18721 gagttggcct tttctttttc gagagagcgc tgaataaaaa aactctaatt tttaataaaa
    18781 ataagcttta ttttatgaat tttgcatccg gtttcggtaa aatagtagtg ttgaatgaaa
    18841 tagaaatgga ggccatcaga tgattggacc tatagtaaga gaaatgctgc tggaaaatca
    18901 ggaaacgttt ttgattcctg cagaaaatgt ggcaaatgtt atgtatcatc atccattgtc
    18961 ccatggttta cttgtgttat cgaaggtcgg ttattccaaa attcctgtat taggaaaaga
    19021 tgatcacttt gtaggactag taagtttatc agatgtggtc aataaaatga ttgacttgca
    19081 aacaatcagc atggacccgt tagaaggact aacggttgct gatgtgacag aaacagatgt
    19141 tccgacaatt gatgaaaatt gggaactaga agaagtactc catttgttag tcgattcgcc
    19201 ttttttaccg gttgtcacag aagatcggat tttcaaagga atcattacaa gaaaagagct
    19261 gcttaaagcc gtaaacttca tggtgcatga attagaacgt cgtaatatat tgtctccgaa
    19321 aatcgaagaa ttaaaagaac aaatcgatat cgtgagctaa agaacgagaa actaaaagat
    19381 aatcaaaaaa taagtagaaa aaacagcgta ccagttttga ctttatcttg aaaaagaggc
    19441 tgggacaaaa gc
//
LOCUS       DADQCX010000054        19217 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.054, whole genome shotgun sequence.
ACCESSION   DADQCX010000054 DADQCX010000000
VERSION     DADQCX010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.054"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1235)
                     /locus_tag="J8R83_001734"
     CDS             complement(<1..1235)
                     /locus_tag="J8R83_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAZ9574864.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="J8R83_001735"
     CDS             complement(1228..2820)
                     /locus_tag="J8R83_001735"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAZ9574865.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3330..4055)
                     /locus_tag="J8R83_001736"
     CDS             complement(3330..4055)
                     /locus_tag="J8R83_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574866.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(4209..4535)
                     /locus_tag="J8R83_001737"
     CDS             complement(4209..4535)
                     /locus_tag="J8R83_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574867.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(4572..4937)
                     /locus_tag="J8R83_001738"
     CDS             complement(4572..4937)
                     /locus_tag="J8R83_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAZ9574868.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(4974..5189)
                     /locus_tag="J8R83_001739"
     CDS             complement(4974..5189)
                     /locus_tag="J8R83_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574869.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            5318..5653
                     /locus_tag="J8R83_001740"
     CDS             5318..5653
                     /locus_tag="J8R83_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574870.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(5729..7726)
                     /locus_tag="J8R83_001741"
     CDS             complement(5729..7726)
                     /locus_tag="J8R83_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574871.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(7824..8099)
                     /locus_tag="J8R83_001742"
     CDS             complement(7824..8099)
                     /locus_tag="J8R83_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9574872.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            8331..9065
                     /locus_tag="J8R83_001743"
     CDS             8331..9065
                     /locus_tag="J8R83_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574873.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            9104..10246
                     /locus_tag="J8R83_001744"
     CDS             9104..10246
                     /locus_tag="J8R83_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9574874.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(10874..11359)
                     /locus_tag="J8R83_001745"
     CDS             complement(10874..11359)
                     /locus_tag="J8R83_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HAZ9574875.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(11361..12797)
                     /locus_tag="J8R83_001746"
     CDS             complement(11361..12797)
                     /locus_tag="J8R83_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574876.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(12830..13681)
                     /locus_tag="J8R83_001747"
     CDS             complement(12830..13681)
                     /locus_tag="J8R83_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574877.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(13837..14082)
                     /locus_tag="J8R83_001748"
     CDS             complement(13837..14082)
                     /locus_tag="J8R83_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9574878.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            14187..14960
                     /locus_tag="J8R83_001749"
     CDS             14187..14960
                     /locus_tag="J8R83_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574879.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(15013..15327)
                     /locus_tag="J8R83_001750"
     CDS             complement(15013..15327)
                     /locus_tag="J8R83_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574880.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(16846..17064)
                     /locus_tag="J8R83_001751"
     CDS             complement(16846..17064)
                     /locus_tag="J8R83_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574881.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(17079..>19217)
                     /locus_tag="J8R83_001752"
     CDS             complement(17079..>19217)
                     /locus_tag="J8R83_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574882.1"
                     /translation="PTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYIN
                     KTDQYSSIDKTEDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSN
                     NEFVATKFSDNFLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILE
                     LAFKRVLGVLVFATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQG
                     ISTNIFIKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGS
                     TGFNRAKGSGNGNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASD
                     GATMASERAIKPFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKY
                     ADSMPTRLSDRKDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEE
                     RKNAMHGQAKSAEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKER
                     IQEAKNSNTGLEKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSS
                     SNGQGTKTIDVRENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQ
                     GFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSK
                     PRRRFTYEDNELFRDTLNDPNPLFDNLLKK"
BASE COUNT         6022 a         3579 c         2673 g         6943 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
     2941 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
     3001 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
     3061 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
     3121 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
     3181 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
     3241 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
     3301 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
     3361 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
     3421 aaccgaagtg gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga
     3481 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
     3541 gtgattcctt tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct
     3601 acaaatgaat taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct
     3661 gtatatatgg cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca
     3721 ttagttagta aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc
     3781 ctaacagctt taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct
     3841 tccataaacc ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct
     3901 ttcatttctg agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc
     3961 tgattcgttt ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt
     4021 gccaaacaaa tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat
     4081 aacagtgact aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca
     4141 aaaaaactcc ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata
     4201 catttaaatc aatttaacat taacacctca gtatatggta tctctacata tacacggtct
     4261 ttttttggat agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta
     4321 gcccggtacg tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt
     4381 aagttatact gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca
     4441 gatgaacccg tcattcttga aaaaattata cctataatag ccaatacaac gatacctata
     4501 atgacaaact tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg
     4561 attttctctc atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct
     4621 acccctgcta tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc
     4681 ataataacag caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa
     4741 atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc
     4801 atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct
     4861 gtttcttgta atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca
     4921 cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg
     4981 tttactttat taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa
     5041 agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat
     5101 tgctgtgtaa cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg
     5161 tatcggctga gattacttac ttttttcatg attctcccct cctgttttat tatatacaac
     5221 aatatgatgt atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa
     5281 caacttgttg tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa
     5341 ggtcattaga gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat
     5401 cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga
     5461 tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt
     5521 tgacatagat tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc
     5581 aattcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct
     5641 attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa
     5701 ataagattaa gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc
     5761 ttactctccg tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa
     5821 ctcctgataa tatcaattct tttattactt catctatccc tgcccctttc gctagatata
     5881 ctaaaaaact actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt
     5941 caagagtgaa tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc
     6001 tgttatccct gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca
     6061 ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca
     6121 attgtttttc cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt
     6181 tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt
     6241 tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa
     6301 cgtctaatcg atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct
     6361 ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta
     6421 tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt
     6481 taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac
     6541 tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca
     6601 tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt
     6661 caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt
     6721 tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa
     6781 ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc
     6841 cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta
     6901 agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct
     6961 cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt
     7021 ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc
     7081 tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag
     7141 taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa
     7201 aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt
     7261 attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa
     7321 tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat
     7381 tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac
     7441 tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta
     7501 ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa
     7561 atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat
     7621 ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt
     7681 tttctttatc tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct
     7741 tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct ttattactat
     7801 atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca
     7861 gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca
     7921 tattttctaa tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata
     7981 tactctagag tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc
     8041 tctttcactt gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata
     8101 tttccccctc ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt
     8161 gctcaaaata aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt
     8221 catcgacata cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat
     8281 ttacaacacc ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac
     8341 gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa
     8401 gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa
     8461 ttgacaaaaa gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat
     8521 tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag
     8581 aagaatatat tttgggaatt attctttata gagatagcat tgtactagat ggtataacat
     8641 ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt
     8701 tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta
     8761 acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag
     8821 aagaattatt catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta
     8881 gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag
     8941 acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac
     9001 aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca
     9061 tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa
     9121 gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc
     9181 acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca
     9241 aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga
     9301 tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc
     9361 ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa
     9421 gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag
     9481 taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac gctacggggt
     9541 tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga
     9601 gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt
     9661 taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat
     9721 gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact
     9781 acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa
     9841 aacaagagct tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa
     9901 ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga
     9961 gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg
    10021 gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca
    10081 tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt
    10141 agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc
    10201 taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa
    10261 atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg
    10321 ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt tgggaatcag
    10381 aggaaagaat caggctttat agagatattt catctaacaa attactttag actgacagta
    10441 tatatcagca ggtactgtca tcgggaacgt agccaatatc gtatccaaaa cagcaggtag
    10501 agaagctatt tgaggattca agttattcta tttcaaccat gaagttaagt tcattaaaaa
    10561 taaagatagt tggtatttca ataatttttg tatagagtta atcactttat tgatgctaat
    10621 tcatcttgat tggtattata atcgtattca agttgcgtgg cgtgcttttg ctagaaaata
    10681 tataactgtt ctttataaag aaatataagg attaaacatt ttttatcata gagttttact
    10741 tatctataga attatgtctg ttcctaattc agtttgatga attaactgat aaaaaaatat
    10801 ctactattta aagatacagg gataagtaag taaaaaaata acatgtcatt agatagtaga
    10861 cagttccaac tctttattta ccttttttgt atgctgcact gtcaatccaa gttcctaaat
    10921 tgttgtatcc atcatcactt atataatcat attggccatc aataatttcg tcaaaccaca
    10981 aatattctcc atctggtttt tgcccaatta ttttaattac tgattgacta gtagttgtca
    11041 tctggttaaa atcttttatt ttacctatat taacggccaa aatagcattt cctcgcttat
    11101 aactctcctg gatttcatat ttaacatatt ctcgatcaag agtttcttta cctatcagca
    11161 ccacagtcac tgatgttcca attaattgat tatctatcca gttttttata gcaatatctc
    11221 cattacgttt aactttctca aattcagcct tatctacaaa accagcttcc tttgttcctc
    11281 gcaaagtcca gctgtttcta actaccattg ctcttgttac atctgcataa tggaaactaa
    11341 aaaaaaccct tctcaccata ttaatcctcc tgaatactat ttattaaact gacaatttgt
    11401 tcaacttttt tatctacttc tccttcagta tctaattttt ctagcgcttg aaatttactt
    11461 tttaaggaat catcaaaata atcactgaaa ttctcttgaa tcttatcaaa caaaacctta
    11521 cttgcacctt tggtaaatcc aatcggaact actatatttt cattttgaac agataattca
    11581 aattcttcaa tcattccatc tgctgtaact atttcacctg attcaagttt gtttccaaaa
    11641 acaaaaatac taatcccaga ctctgcaata atgttttctc gatatcttct ccactcatga
    11701 ggcatatcaa ggggaagtgg tcttaaagaa agtacgtctt gtatgttatt ttttcttaaa
    11761 tttcttctct gctttagaac tcctgaaaca atactattac caattccaag tccgtaacct
    11821 gatactattc tataaccgga ttcagaaagc ctatatgcta atttctcgac aaattttaat
    11881 cctttcgatt cagatgtaaa tggagtataa tcaacagcac ttcccgaaat aaaaatagtt
    11941 tttctcaaat acttttttct aatacttttc aaaatatcag taatctcaga ataatcatct
    12001 acttcaacaa cgtttatcga aaatctggac aaatcattga tttgtagtct tctttttgtc
    12061 agttcataat tatatctctc ttgatcaaaa aaatcctcag aatcgacaaa attttccttt
    12121 aatatttttc tcattataca ataatgaggt ctttggtttt ctctcaaaac ccatcttata
    12181 tctgataaaa ttctttctaa attagggtct gtaaaactaa atcctaaaaa gagaaaagtt
    12241 tttgttaaca aatctccttt taaagtttct ttaaataacg cgtacgaatc atcatcatat
    12301 ttttcataat catctcttgt tattactgtc gaactgacat catctatatc accatgcatt
    12361 ttataaacaa ttgtatccac atttggatta gttgttgcta actgagtata atttttctta
    12421 acctgagggt ttttataagc ttctcggatt gatttttcta ttagatgatc ataattagtt
    12481 gtccaataag tttcaatagg taaacttgct agtattcgat gattttcaga tatttctaat
    12541 tcttcaccaa aattatccat aagtatctga ttcaaaattc ctcttgatcc accattttca
    12601 tttttataat attgagccag agtaactaag tctgtttctt ttttagaatc caacccgatt
    12661 tctgttgcag gatcattaag tagttccggc caacttacat atccttgtga catcgataat
    12721 cctgcacctg caaatattgc tgcatttcct ttttcaatag cttcagagaa cctctttatt
    12781 aaaactttct tatccattct acccggttcc tttcgattca gtaaattgat tagagattag
    12841 tgaaaatggt gtttttatat aaaatatcta atgtattact tcctttagtg cattccacag
    12901 catctaaagc ccattttttc aaatcagctt ttcgtaaata agttaattca cttaaattta
    12961 aagaatattt tatttgcaga ttttcttgcg aagaatagtg ctttataatg cttctaacat
    13021 cctcggtgct catttgagga ttactttcca atcgtggatt ctttttttcc actattgaag
    13081 ctgtcgtcag ttcgctatat agccatggcg aatacgtaaa tttctgttca ttagtgattt
    13141 cattgctcaa actaattgaa ttaggtgtat taagaaaaaa cagacattct gtactatcaa
    13201 tcatattatt taaagctgta gaaagcatca tatgaacatg actagttgtt acatttcttt
    13261 tatcataatc atatgttttt gtttgttcct tatagcaata tttttggtct atttttttta
    13321 ataaatcaga actgtatccc caaaccgaag aatcaataaa tgcagtaaga ccaaaatttt
    13381 caaatagcca tgatgcaaaa cgtatagcta atttttcatc agcatgagag tgagatataa
    13441 aaatatctgc ttttatagtt ggaaaccaat ctttaataat ttcgtctgca tctagaattt
    13501 tgctgtcctt agaataataa tcaactaaat cattttcact ttcaaataga ttttctattc
    13561 tcttgttaat agatttttgg ttgtgatcta tttgatttac tacatgtgta tatgattgcg
    13621 agcttgagga gaatgcattt aagtcagcat ttgtaaaatc caattcatat gccttataca
    13681 aggatatccc tccattcttg tattttgatc cacaatttat taggcaacat aacagtatac
    13741 cctatcgtta catatcccat tcattattat accagtattt cttcgtgaca cataagggtg
    13801 taacataata atttcaaacg aaatgactac aagtagtcat tgaagcaaat cttcataaga
    13861 cacctgtaga atatctttga tggctttcaa ttgatccaac ttaatgtgtt ggcggccacc
    13921 ttcaatctta accaacgttt ccctagttat agcaatttta cgaagctgta ggtctctaat
    13981 cagctcggtt tgaccaattc ctttttctaa tcggactcgt ctaatattgc taccgattac
    14041 attttcttta tcaataattt tttcctcttt caagaatagc acaccttttg gactaaaatt
    14101 agtccttttt cttattaatc ttaaagattc ggtatgctac aatgggacta gtattagtcc
    14161 atattcaatt ttaaggagga atttttttga agaaatttgc aatcattcta acttgcgctt
    14221 tactcatcgg aactataagc gggtgtacca cttctgacac aagttctaca agtacggaaa
    14281 ctagtacaac aacctcagaa aagaattacc caatacattt ttttccggtt ccagatggat
    14341 ttgaagctta ttatcatgat aaaaaactag atgttccttt atcagaaact gaatctactg
    14401 aaaagatttt gccaattgaa attgaaagaa atcaagacga tataaaacta aaagctgatc
    14461 ttcccttact gaacagcaca caaattgata gacatgaaaa tattaaagtt aatattgaaa
    14521 aaggagcgtt agcacaactt tatactgaaa aagttgaaca attttttgag gctggtgcca
    14581 ataaagactt ttcaaaaata agcgattatt cggataactt ttttaatgag acccaagatg
    14641 aaatcacgaa ctcaactttt atggctgaag atatgtacaa tatgaagttg aaaaaaataa
    14701 agtcgtatga ttatccatta aatctaacat taaataaagg gatactctct tttgtattag
    14761 caggttacgt tgactatgaa tatacagcag attatttgga gacgcccctt caacacgata
    14821 ataacgatat taattttaga tttatctaca attcaaaaag taaaacatgg ttagttgatc
    14881 aattgagcac tataaatacg ggatttcatg aattacctaa gcctgacaat gaaactgctt
    14941 tggtcattaa aacattctaa aaaagaaacg ttgaaggaat aattattctt tcaacgtttc
    15001 ttttattgtt tttcagttta cggtcttacc tgagcgaata atctgatttc taaatgattg
    15061 gaaaacttct tgtggttgat aataatctgt atctatttca aatgtttctg agaataattc
    15121 attgaatttt tctactgaaa tgatgatttt accattctcc tctcgactgt tttctattat
    15181 ttctgcctct aattcaaata aatctagtga cgaactaaaa tcataaatcc tgtcatattg
    15241 aacaaaaaaa tcaagaaaaa gttgctcaaa ctcttcctta tttatcacta gtgtttcaag
    15301 cggaacaact ttattttcat cagccattct tccaatttcc tcactttcat tttcaattgt
    15361 ccattgttgc ggacgtatca gattttctct atcatttttc agtgtataga tcacttgtaa
    15421 tacacaacaa tgctttgtaa acttattttt ttagttagtc gaatcttttt aaatgtgcgt
    15481 ttcataccat gcgcttgata tattttctcc tattttttaa atcgtttatc acaactttta
    15541 tcgttttttc ttctgaaaaa aatcttgttt acatcgttac atagtttcca aaaagataca
    15601 ttactagtag aaacaacaag attaatttta cttcccactg aaatgggaag tatattttaa
    15661 atattttttc tccttcaact tacactataa agtatcttaa tcacacgata tgctagccac
    15721 taaattcatc atatttgatt ccttttttaa gataatgtag catcttttta tccaataacg
    15781 caattgtttt taaggataaa tttcttaaga tggtacattt caaaatggca tttgacatat
    15841 gaaacaaaaa agaaagaaaa gagcataagg gaaaactgat agcaccttcc tacaggaagg
    15901 tggctaagtt ggctgtgcca actggttttc tttcaaaatc atttcataat ttttgatatc
    15961 ataaaaaaat ccattttgga cctattttcg gtcataattt agtacctact tttggtcata
    16021 gtttcgtccg tagttttggt catagtgact aaggcttttc tgttcacaaa attggtttaa
    16081 atttgctttc tttaacactt catttatatc atagcaatta taatgtttac acaacatcat
    16141 tcctaatttt aacggttgtt cctctttata ttttttaagt tctacatttt tttgcgttta
    16201 attacttttc tcttttcttt atattccgct ccaactttct ctttaatagt gataatagaa
    16261 ttacatattt ttgttaaact tccttaaaaa aattggatct cgattactca aatttgcttg
    16321 caggcttttc taattgcttt gttttttctt cctaattatt tgattttatt tccattttct
    16381 tctagtgaaa atttattatt tttaataatc gtacgcgtag aactgatttc attttttgta
    16441 tctgtttgat tatctaacgt ttgaaattca aagttttgat tggctttatc aatatctttt
    16501 tatactactt tatttgcaag atatattttc ttgcttaatt tggtcatagt ttcattcgtc
    16561 acttcggtga tattttttta atttgcaaat aaaaagagtt aaaccgatat acattaggtt
    16621 caactctttt gcaggtttca tgggtgtact atcactttta atctgataga tgtaaacctc
    16681 tctttatctt tttgttactt caattttcaa caatagctcc tttataggtt gtcaatattg
    16741 ctctacgtat tctggctttt taacccatta tttctctaaa gtggaagaga ataatcgctt
    16801 aatccccact aattccttgt cgtaaattca tgtcaaatac aatttttaaa agccatttaa
    16861 ttcatggatt atctcttcac ttttttctag ataacaatat ttcaagttgt tttttatctc
    16921 atgtttcatc tttaattctt cttgaatcat cagttcaata taattagtga ccgtgatttt
    16981 ttcatttgtt gcgttcttta ctgattcaca taattcgtca agttctaaga aatcatgcgt
    17041 actaatcttt agaattaatt tcatgacaat tccccctttt atttttttaa tagattatcg
    17101 aaaagcggat taggatcatt aagtgtatct ctgaataact cgttgtcttc ataggtaaat
    17161 cttcgtcttg gttttgatcc cttatcattt tcacggattt cactatcaat aatcactgtt
    17221 tcatgatttg aatcaaattt tttcgctgac tttctgtctt caacgatatt gattttttgt
    17281 gttttttctt tcatttctcc actatctttt tgaacgttct cccgaacatc tactgttttg
    17341 aatccttgac tacttgtaga actttgtaca ttctctctta catccattga tttaaaccct
    17401 tgactacttg tagaattttg tacattctct cttacatcca ttgatttaaa cccttgacta
    17461 cttgtagaat tttgtacatt ttctcgaaca tcaattgtct tagtaccttg accatttgaa
    17521 gagctttgta aattctctct tacatcaaca ttccgtccga catgaccatt caatgaacct
    17581 tgaatatttt ctcggacatc tactgatcgg ccaccttgac tacttgtaga attttgtaga
    17641 ttttctttga ccaatttttc taatccggta tttgagtttt tagcttcttg gattctttct
    17701 ttggtcaacg cttctttttc gtccgtatta gctcctgtac gcccttctac acgtttcctt
    17761 aacatttcct cacgattcat tgcttcaggc gtgtatttag cttcttgtcg cttctgatta
    17821 attaattctt cagcagactt agcttgaccg tgcatagcat ttttacgttc ttcaatatct
    17881 tgttgaactt tttgctgaat tgcacttaca ggattattat tcgattcagc attatttttc
    17941 attgcttcac gcatacgttc agaactagac ataattctat cggcattttc aaccttagca
    18001 ccatcttttc tatccgaaag acgtgttggc atggaatcag catattttcc agtttcatct
    18061 tctttatttt tagctaacat aggtttgcta tttttattaa tagcggacac tgtaccatca
    18121 tctaaacctt ctttgaactt attcttggta tcattagcca tatcacgcat actcttaaat
    18181 ggttttattg ctctttcact agccattgta gctccatctg aagctaaacc tgataatcca
    18241 cgttcatggg catatcccaa agctcttcca gttttgccag ctttttttga tagagtttcg
    18301 ccgaaattct tttctggttt tcgatcttct ccttctccac tgtctgatcc atttccattt
    18361 ccgcttcctt tagcacgatt aaatccagtt gatccttttc taaacagcat tgcgcccata
    18421 ccaaaagcag aagcaagttg cccatagcct tctttgagtc caatatcaac accaaagtat
    18481 ctcatgactg ttccactgcc ttttatcagc acaaacacag cacagatata agcaattgtt
    18541 tttataaaaa tatttgtgga gataccttgt ccagcattta aaaaattgat aaacatagca
    18601 aacatagata gtccaaaccc ttgaaatcca actgttaagt aacattgtaa aatatcggat
    18661 aaaacaactt ttgaacgttg tcctgtttca atatctgtcg caaaaacaag aacacctaac
    18721 acacgtttaa atgcaagttc taatattgct gtaatgatca caaacgcgct gaacacatag
    18781 gcgattgcca acgctgtcaa cccaatcgaa atcccccaaa gatttgcttg atatcgataa
    18841 taacctgatt tcaagctatc agaaaatgtt gataagaagt tatcagaaaa ctttgtggca
    18901 acaaattcat tattagaatt ttcaactaat tcatagcgaa gattatccgc agctggattt
    18961 tctttttcca atttatcaat cactttatcc gtcaacactt gtgttaaatc tgtctgttga
    19021 aaattttttc gtgttaactt atttcgatcc tccgttttat caatgcttga gtattgatct
    19081 gttttattaa tatatgccag atctgttact ccttgtttta tcaatgacca agcgactccg
    19141 tcatctgaat ttgtaatcgt agtagcatca ttgtaaaata ttttggcaaa ttgaataccg
    19201 ctagaaatca ttgttgg
//
LOCUS       DADQCX010000055        19059 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.055, whole genome shotgun sequence.
ACCESSION   DADQCX010000055 DADQCX010000000
VERSION     DADQCX010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.055"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            239..919
                     /locus_tag="J8R83_001753"
     CDS             239..919
                     /locus_tag="J8R83_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HAZ9574883.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
     gene            1702..5355
                     /locus_tag="J8R83_001754"
     CDS             1702..5355
                     /locus_tag="J8R83_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAZ9574884.1"
                     /translation="MKKKKSVWFMMVAILMGFIPQILTAYSSIAQAIETQPDKIVDQS
                     GLKVSSSVSSDGNSLNWELQYEKSVASDGNDQALKFKVTADGEAIAFNEDASFAVDDD
                     QWFAEKDFSKQSQGSLSFTTVLNVSKVALEIQADATKTDGTQAVTINKNILTSAVEGP
                     HALKLPAVATQKTTEVSATSQTTAEETTSSQATETTTQTEEASEAKSSEINASPATVG
                     ASNLEYLSGISAFSSINYSNIAPEYTTDATKGTYPTNSWQPAGQTNVINHQGNKERNF
                     ATWDGVTSWNGDPSDTTHSYIQYGEKQTDFAIRKYAKETSKPGLYDVYLNVKGNKQED
                     IKPVDIVLVVDMSGSMESSQSNGWNDRAGAARNGVKNFLQTIKDAGIGDYVNVGLVGF
                     SSPGYVTGPNGYLTVPIGKASDTSHINAINDALKPKFTGGTYTQIGIEQGQQMLAGSS
                     NENKMMIVLTDGVPTFSKKVTAAQTIDGTTYATEFGNRLDEPSTTSGLPWWDRYTVDR
                     TLINSTWPATLGAAKIAKDAGLTIHLLGIQLSKDRNFLTEQQVRDRASLIATPGKYKD
                     AETTDDVSDYLNEQAKNVVKSFNTIVNGSINDSLGDQFSYEGTPTVKSISTGDSAVTN
                     LPTVNQSNGKVTTTELNLGKDQEIQIHYQVRINTEDKDFTPEKWYPMNGQTTLTPNGD
                     NPDNKVDFGVPSAKAPGVKLDLKKIWEEYDKDTSKRPDSLNFTLNRKDTTESNSWKQG
                     FIRLSKSDVATDTNVWEKTNIEKVAETQGATESLWLPQFNNKGKDFAYSFEEATVNGY
                     ESSSNAATTIWTNKKIYTPLALEITKISDQGKTPLKGAVFKLSGGSLPNAGVELKDNG
                     DGTYTLSDDKYKLQLNTEYTLTEVTPPAGHTATTTSWKVDVSAEGKVTINDAVPGIEI
                     KDNTIKYTIENEFTKRPLLVEKYNKDSGKTLDGAKFTLKQYDDKWTNDGKVVGDDLIG
                     NDAKSFASLAPGYYSLEETKVPTGYKKDDTVFKFQIDSAGKLLDANGKEITANSKPTT
                     DGFYLTSDNKIVLIKYNELRDFDFSILKKNSQSNKPLADTEFSLATKEDSNTILATLK
                     TNDEGTGQFLDASGNHYGVRPGTYVIKETKAPEGFVLLKGIFEVTINADGTVGDVTYD
                     GKDLDKDAIKVNLKDEDNNVIELTVANTPKGQLPATGGSGIQTFIIVALALVTAAGAL
                     TICYFYRNRKELN"
     gene            5357..6088
                     /locus_tag="J8R83_001755"
     CDS             5357..6088
                     /locus_tag="J8R83_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9574885.1"
                     /translation="MKNKSLFIKITILLSTLLVGIFTGQQAFADDGTIDIVIHKQLWD
                     QAPDAAIQNTGAADQDIKDPIEGVGFTIYDITEDYYKLVKGSDETTTIQMIQENVADY
                     QKIIREQGLTDEKSTIKFTQLPKSSGGKNAVYLIVETALPDLEKVKVEKAAEPLVVAL
                     PVYEMSTDGKTYTDKELATVHLYPKNVGTIVEKPVTPTKPKKPSKPKKHLPQTGEAKS
                     FLGILGILLIGTAIILWRKHSVRNN"
     gene            6153..7640
                     /locus_tag="J8R83_001756"
     CDS             6153..7640
                     /locus_tag="J8R83_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9574886.1"
                     /translation="MKKLWKTLFAALLVVPLFTGVFGEKTVSATEATTTNVTINKRIW
                     KDGEAPAQGSMQNTGEEMDFGGDPLEGAGFTAYDVTDAYLALIADGKSQAEATKEIAD
                     NASDYTTVAKAEQKTDANGQTTFEGLALKDGDKDKVYMFVETSTPGNVSVTTKAAPIV
                     LAMPIYTFKDGKYSDTINTNVQVYPKNETKTDKKEVANLDKFTEVKDADGNVLYHNLT
                     TGDEIEYKLTLNIPADILEDGVTYSVTDTPTAGLAYVKDSFAATGLVAGTDYELAEDS
                     ATGGFTVTLKQSENVGKLAGSQLIATYKMKLTAEVNPDDLVNNSAQVTIGNNPQDKIT
                     PPTQFGTGGYKFVKKDSQSGATLSGAEFVVKQGSNFAIFEDAKNTKGEYIFKEWTTDE
                     AKATKIISDDKGELKVIGLKNGDYQLEEKATSSDKYVLLDEDVDFTVEHGQYGSQELK
                     SVLNTPKGLLPSTGGNGIYAFLLIGAALMIGAYAWFKKSKTQAEV"
     gene            7726..8922
                     /locus_tag="J8R83_001757"
     CDS             7726..8922
                     /locus_tag="J8R83_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9574887.1"
                     /translation="MDQRQKNERINLILKLLMAILFTTGAIIFSYPFLSNAVNSYYDQ
                     KMMEKNLAEMAATNTKEQAKRHQEMAEKNKELAESKNMTNIPGMGLVEDPFENAVDDA
                     KDPGKAYYEEHTVGAIYIPKISVSLPLFDETNAALLEKGATILQGTSYPIGGDSTHSV
                     ISGHSGLTERKLFTDLEKLVIGDDFYLTIAGEKLAYAVDDIQIVLPSDIDKVVIQPGR
                     DLVTLLTCTPYGINTHRLLVTGHRVPYVEEMAEEVTSTKKAVERRFRLYLLLIPLFFA
                     MVFYWMYRKFVYYQSGKHSYDFCFYLLENGQPKAGVTFTLVRKKRWATDVTSQPVAVS
                     QVDGWVSFPEIRGGRYYAKAIDGSTKPVKGKVRRLKDRQFVLSRVTKKKHGKKVTYYL
                     ENGAKK"
     gene            8919..10040
                     /locus_tag="J8R83_001758"
     CDS             8919..10040
                     /locus_tag="J8R83_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9574888.1"
                     /translation="MKKNRQVISQIAIILIFMVGILTMLYPFYVDALNNVIDQVRVDR
                     YLKESQKEFEAERKRLAEENSKLSESGLAPGADPFANPNGGTVSAAYYKKHLIGTINL
                     PDLAIELPLFDTTNDDLLEQGATVLDGTSFPVGGASTHAVISAHRGLPERELFTNLPE
                     LKNGDIFLLNVLGETLAYEVFDSQVVTPDQTSVLKIEPGQDLVTLMTCTPYMINSHRL
                     LVTGKRVPYTPAAEKKQVKGDRFRKLKQIAILAGTALLILAAIYQLYHVIARYRLRKV
                     RFDFTVCLEGVAEHTPIALYDKKGKKALRRNGKAYQELTDQTGQVTFTDLPGDCYRLK
                     LGKSWLVQFGLKKKKRPSKIWKINKKKVMLKEERMLEVK"
     gene            10761..11753
                     /locus_tag="J8R83_001759"
     CDS             10761..11753
                     /locus_tag="J8R83_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574889.1"
                     /translation="MSKDNKDDDLVKNIRKYATTKRLNFLLGSGVSYPAIPLMGSIEG
                     KSEEEKNGKLLEKVKLVSDKLVTNEFCNDTDIYYTLRMYREFILNIIGILHLSNSRQI
                     PRTANIFTTNYDLFIEKATDKVLKNFKFVFNDGASGYFDRKLESTNYNRTVSYKGLND
                     NYTNELPSLTLIKPHGSVNWEKNEEFLYIRNHVIANPCVVKPTGREEEETFLSNHFHE
                     MLRIFQLELDKPQTILFVIGFSFQDKHIAKMLKRALQNPELMTYIFAFDEVDKDKITS
                     NLSHEVGQYNLNILIPKDFSENHKQKNDKGAEFFTLKNLNSILNNVTIGDSKYD"
     gene            11746..13626
                     /locus_tag="J8R83_001760"
     CDS             11746..13626
                     /locus_tag="J8R83_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9574890.1"
                     /translation="MTNPSKKLGVITAVDGDIAQVGMYNMSNDSEFFWYGETLIGPKI
                     GAYLTINQNDNKIIATVINEKIIDQQNSIKSEEFDNRYSKQSINRIISLKTKGVIEND
                     KFQVTSQYVPMIGNEVSLTNMEDLKIIYGINNAKDSIKIGYSILEKQPISLSINKFFA
                     SHIGIFGNTGSGKSNTLHKLYLELFKSEYYEKIVEKSQFFVIDFNGEYISSKTNEKTQ
                     KGIFGVHKDNRTLFKINTRNEDKSSKIPVKKEYLFDADILSILFDARSATQVPFLRSA
                     VREFMKKQNEPFFDFGSYVTGTLKKILTSGLSVNQDSLQDWLDIAKKYLKRDLEFKYL
                     DQLVQFNNGDFKINSLDIWFSKGVETNISDDILTRSGINNISVMLKEYFDNNKDTPLQ
                     QLRIFLDFQKVHRTAWGKINREHLNPLFNRINSSLESLEKVIEIKEDAIGCYKTLNII
                     SLVHANQEITRLVPMLLSKMIYDEQKSKTAGKKVSGTKHLIIDEAHNILNSEYKNNGD
                     SWQDYRLSVFEEIIKEGRKFGFYLTLSSQRPADISPTILSQTHNYLIHRLVNENDLRM
                     LEKTMPTLDKTSYNFIPSLGKGEAIITGSALSIPVLVKIDKETDLRPSSDDINLTSLW
                     ND"
     gene            complement(13655..14260)
                     /locus_tag="J8R83_001761"
     CDS             complement(13655..14260)
                     /locus_tag="J8R83_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9574891.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLENGVAISKISKEYNVTRQTVYRIKNELNT"
     gene            14455..15507
                     /locus_tag="J8R83_001762"
     CDS             14455..15507
                     /locus_tag="J8R83_001762"
                     /inference="COORDINATES: protein motif:HMM:TIGR00341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HAZ9574892.1"
                     /translation="MSENVYYSAKEFYAKINQDLTIRREDMVILVCSIVIACIGLNMD
                     TTPVVIGAMLVSPLMTPIQGIGMGLSLFDQQMLKKALKILLVQIMVSIVTASIYFFIS
                     PISYASNEILARTQPTIWDVIIAFFGGIAGVIGSRKKAMNNIVAGVAIAAALMPPLCT
                     VGYAIALKKMPYFLGAGYLFLINCFFIIIATFIGVQVMRIPKSVKVDSEEKSKMNVVI
                     VILSIVILIPSIISASQLVGKSIIENGLRRMLSEELGNNVIVINKSIDQENKIIYLTT
                     SGEKISDTRIKKIEESLPMYNLKGMSLEISQITNTQQLSGEDLVRLLKEYEESKKSNS
                     IEKTKRVNSTEDSNNE"
     gene            16078..16662
                     /locus_tag="J8R83_001763"
     CDS             16078..16662
                     /locus_tag="J8R83_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9574893.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSLQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLKAQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLDKMEGKDGKTNTH"
     gene            16640..16855
                     /locus_tag="J8R83_001764"
     CDS             16640..16855
                     /locus_tag="J8R83_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9574894.1"
                     /translation="MEKQTLTSFSEQQRIAAMKKYKIIEPYLNKQKTIKEIAIKNKAP
                     TRTLYRWVQKYEHDGLVGLIRKTRTDF"
     gene            17176..>19059
                     /gene="topB"
                     /locus_tag="J8R83_001765"
     CDS             17176..>19059
                     /gene="topB"
                     /locus_tag="J8R83_001765"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAZ9574895.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGQYNEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIYQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLSFVSSNHAKIGNQEGRIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGEHAEVDVKSAEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKS"
BASE COUNT         6665 a         3068 c         3846 g         5480 t
ORIGIN      
        1 tttaaacggt agttacttag ttcttctttg atttgcgtga aatagagggg atttattttt
       61 ctggttacgt gattaaaaaa tccaaaaaat gagcatagga acggttatga ttttagggtg
      121 tgttttaatg agatattgtg atttcattaa caagtgtatg ataatcggtt cttttgcaaa
      181 gttttccaaa aaatctattt tagtgtaaaa ttgagaaaaa aacagagagg acagagtaat
      241 gaatcatttt aaaggcaaac aattcaaaaa agacgtcatt attgtcgctg ttggttacta
      301 cctgcgttac aatctaagct atcgtgaagt tcaggaattg ttatatgatc gtggaataaa
      361 tgtttgtcat actacgattt atcgttgggt gcaagagtac agcaaagtcc tctattatct
      421 ttggaagaag aaaaatagac aatccttcta ttcatggaaa atggacgaaa cctatatcaa
      481 aattaaggga cgttggcatt atctttatcg tgcaattgat gcggacggct taaccttaga
      541 tatctggtta cgaaagaaac gggatacgca agcagcctat gctttcttaa aacgactcca
      601 taaacagttt ggtgagccga aagcaattgt gaccgataaa gcaccttctc ttggctccgc
      661 ctttagaaag ttacagagtg tgggtttata tactaagaca gagcaccgaa ctgtgaagta
      721 tcttaacaat ttaatagaac aagaccatcg acctattaaa cgacgaaata aattttatca
      781 aagtctccgt acagcttctt ccacgattaa gggcatggag accattcgag gaatatataa
      841 aaagaaccga agaaatggaa cgctcttcgg cttttcggtg tctactgaaa tcaaggtatt
      901 aatgggaata acagcctaag atatttggag ttcagagagg gcgcgtttga ttttcaaact
      961 tcgcaacaaa accattttag gaatttgagt agtgtcattt gataaaaatt tctcaagcag
     1021 cattcttaaa tggattagtg tcaaattatt gttttcgttt caaaaacatc cttgtatagc
     1081 aagatagctt gttgaacatc atgatgttca acaaggtcgt aacgtttttt tgagtgttgt
     1141 tgtcttcgga tattgaattc aaacaatcac tacttatcac taacaagtca attatcagat
     1201 tgaacataaa agtggattga cagctgaagc agttgcagag ctcaaagatt actcaaataa
     1261 acaatttcaa ggctagtata tgatacaaaa ttcatcatta gggtaaaaag aagtgtttgg
     1321 agatacggta ccttatacga taaaagcgac ctatccattt ttatttctgc tagacaatat
     1381 ctctgtgaaa atcggaattg aagggtaagt gccttctcaa gtgagttgaa gatattggaa
     1441 aagatttttc cttagtgtta cggctcgttt tcagtttaat cgtgggtgcg cttcttctta
     1501 gagtagtcat ttattatcaa gacatcataa aagttgcatg gaaacagtga cggatacagc
     1561 aaagcatagg aatgtgaaag agataacaat ggtattatcg ctataaattg tttataattt
     1621 agatggcagt atcaaatctt aggtagtgct atttaaattt tgtttaagaa tagatatcat
     1681 gttttttaga ggagggaaga aatgaagaag aaaaaatcgg tctggtttat gatggttgct
     1741 attttgatgg gctttatccc gcaaatcttg actgcttatt cgagtatcgc acaggctata
     1801 gaaactcagc cggataaaat cgtagatcaa tcaggtttaa aagtcagttc ctctgtttca
     1861 tcagatggaa attctttaaa ctgggaactt caatatgaaa aaagtgtagc aagtgatggc
     1921 aatgatcaag cactgaaatt taaagtgacg gctgatggag aagcaatagc ttttaatgaa
     1981 gatgccagtt ttgctgttga tgatgaccaa tggtttgcgg aaaaagattt ttcaaaacaa
     2041 tcgcagggtt ctctttcatt cacaacggtg ctaaatgtct ccaaggtagc tcttgaaatt
     2101 caagccgatg caacgaaaac ggatggaaca caagctgtca ctattaacaa gaatattttg
     2161 actagtgcgg tagaaggtcc gcatgcgttg aaattaccag cagtggctac acaaaaaacg
     2221 acagaagtaa gtgctacttc tcagacaaca gctgaagaaa ccactagtag ccaagcgacc
     2281 gaaacgacga cacaaacgga agaagccagt gaagcaaagt cgtctgagat aaatgcctcg
     2341 ccggcaacag tgggcgctag caatcttgaa tatcttagtg gaataagtgc attttcttcc
     2401 attaattaca gcaatattgc gccagaatat acgacagatg ccacaaaagg aacttatccg
     2461 actaatagct ggcaaccagc tgggcaaaca aatgtgatca accaccaagg gaacaaggaa
     2521 cgcaactttg ccacttggga tggtgtaact agctggaatg gcgatccatc agacacaaca
     2581 cattcttata tccagtatgg tgaaaaacaa acagattttg ccattcggaa gtatgccaaa
     2641 gaaacgagta aaccagggct ttacgatgta tatttgaatg taaaaggtaa taagcaagaa
     2701 gatatcaaac cagttgatat tgttttggta gtggatatgt caggaagtat ggaatcgagt
     2761 caaagtaacg gctggaatga tcgtgctggt gcagccagaa atggtgtgaa aaatttcttg
     2821 caaaccatta aagacgcagg cattggggat tacgtcaatg ttggtttagt cggattttct
     2881 agtccgggat atgtaacagg gcctaacggt tatcttactg taccgatagg taaagcttcg
     2941 gatactagcc acataaatgc aatcaatgat gctttaaaac caaaatttac aggaggtact
     3001 tacactcaaa tcgggatcga gcaaggtcag cagatgcttg cgggaagctc caatgaaaac
     3061 aaaatgatga tcgtattgac cgatggggtt cctacttttt ctaagaaggt aaccgctgcg
     3121 caaacgattg atgggactac ctatgctact gaatttggta atagattgga tgaaccaagc
     3181 actacatctg gactcccatg gtgggatagg tatacggttg atagaacact gattaatagt
     3241 acttggccgg ccacattagg agcagctaaa atcgccaaag atgcgggctt aactatccac
     3301 ttgctgggaa ttcagctgag taaggataga aattttttaa ctgaacaaca agttcgcgat
     3361 agagcaagtc ttatcgctac accgggtaaa tacaaagatg ctgaaacaac agacgatgtt
     3421 tctgattatt tgaatgaaca agctaaaaat gtagtgaaat ctttcaacac catagtcaat
     3481 ggttcgatca atgattcttt gggtgatcag ttctcttatg aaggcactcc aactgtgaag
     3541 agcatcagta caggggatag tgctgtaacg aatttaccga ccgtaaacca gtcgaatggt
     3601 aaagtgacca ctactgagtt gaacttaggc aaagatcaag aaattcagat ccattatcaa
     3661 gtgcgtatca atacagaaga taaagatttc acgccggaaa aatggtatcc gatgaatggt
     3721 caaacaactt tgacaccaaa cggagacaat ccggataata aagtagactt tggcgttcct
     3781 tctgcaaagg caccgggggt taaactcgat ctgaaaaaga tttgggaaga atacgataag
     3841 gatacgagta aacgtcccga ttctcttaat ttcaccttga accgaaaaga taccacagag
     3901 agcaattctt ggaagcaagg ttttattcgt ctttctaaaa gcgatgttgc tacagatact
     3961 aatgtctggg aaaagaccaa tattgaaaaa gtagccgaaa cacaaggagc tactgaatcg
     4021 ctttggttgc cacaattcaa caacaaaggg aaagattttg cttatagctt tgaagaagca
     4081 acggtcaatg gctatgaatc ttcaagtaat gctgctacaa ccatttggac caataaaaaa
     4141 atctacacac cacttgcttt agagatcact aaaatttctg atcaaggaaa gacacctctt
     4201 aaaggagcag tctttaaact aagtggaggt agtttgccaa atgcaggcgt tgaacttaag
     4261 gacaacgggg atggaaccta tacgttgtct gatgataagt acaagctgca attaaatact
     4321 gagtatacat tgacagaagt tacaccacca gctggacata cggctactac aactagttgg
     4381 aaagtcgacg ttagtgcaga aggtaaagta accatcaacg atgctgtacc gggtattgaa
     4441 atcaaagaca acactatcaa gtacaccatt gaaaatgagt ttaccaaacg tcctttattg
     4501 gttgaaaaat ataataaaga tagtggtaaa acattagacg gtgcgaagtt cacgttgaag
     4561 caatatgacg ataagtggac gaatgatggt aaagttgtcg gtgatgattt gatcggaaat
     4621 gatgccaaat cttttgctag cctggcacca ggctattaca gcttggaaga aacgaaggta
     4681 ccgacaggct ataagaaaga cgatacagtc tttaagttcc aaatcgatag cgctgggaaa
     4741 ctacttgatg caaatggcaa agaaatcacc gctaactcaa aaccaacgac agatggtttc
     4801 tatttaacga gtgataataa gattgtttta atcaaataca atgaactgcg tgattttgac
     4861 ttttcaattc ttaaaaagaa ctcgcaaagc aacaaaccat tagcagatac tgaattcagc
     4921 ttagccacaa aagaggattc caatacgatt ttggctactc tgaagaccaa tgatgaagga
     4981 acgggtcagt ttttagatgc ttcgggtaat cattacggtg ttcgtccagg aacttacgtt
     5041 atcaaagaaa cgaaagcacc agaagggttt gtccttttaa aagggatttt cgaggtcact
     5101 ataaatgcgg acggaactgt cggcgacgtg acttatgatg gtaaggatct tgataaagat
     5161 gctatcaaag taaatctaaa agatgaggac aataacgtca tcgaattgac ggttgctaat
     5221 acacccaaag gacaactgcc agcaaccggc ggatcaggta tacagacttt catcatagta
     5281 gccttagctc ttgtcacagc agcaggtgct cttacgatct gctacttcta ccgtaatcga
     5341 aaggagttga actaagatga agaataaatc attgttcatc aaaatcacca tacttctttc
     5401 aactttgctg gtagggatat ttacggggca acaagccttt gcggatgacg ggacgatcga
     5461 tattgtgatc cacaaacaat tgtgggacca agcacctgat gcagctattc aaaatacggg
     5521 agcggccgat caagatatca aagatccaat cgaaggggtc ggctttacga tttatgacat
     5581 tacagaggat tattataaat tggtcaaagg ctctgacgaa acaacaacta ttcaaatgat
     5641 tcaagaaaat gttgctgatt atcaaaaaat tatcagagaa caaggtctga ctgacgaaaa
     5701 aagcacaatc aaatttaccc aactacctaa aagcagtggc ggtaaaaatg cggtttacct
     5761 gattgttgaa acggcattgc ctgatcttga aaaggtaaaa gtcgaaaaag cggccgaacc
     5821 cttagtagtg gctttaccag tatatgaaat gagcacagac ggtaaaacct atacggacaa
     5881 agaattagct accgttcacc tttatcctaa aaatgtggga acaatcgttg aaaagccagt
     5941 gacaccaact aaacctaaaa aaccaagtaa accgaagaaa cacttgccac aaacaggtga
     6001 agcaaaatcc ttcctaggta tattggggat tcttttgatc ggtacggcga tcattttatg
     6061 gcggaaacac tctgtacgaa acaattaatc aaaggtacaa aagactaagg tctattgaaa
     6121 tattgtacaa aaaaacaagg aggaattaga aaatgaagaa attatggaaa acactttttg
     6181 cagcactact tgtagtacct ttattcaccg gcgtgtttgg tgagaaaaca gtaagtgcta
     6241 ctgaagcaac aacgacaaat gtaacgatca acaaaagaat ctggaaagat ggcgaagctc
     6301 cagcacaagg ttccatgcaa aatactgggg aagaaatgga ctttggtgga gatccacttg
     6361 aaggagccgg ctttacagcc tatgatgtaa cagatgctta tcttgctctg attgcagatg
     6421 gtaagtcaca agcagaagca acaaaagaaa ttgctgataa tgcgtcagat tacacaactg
     6481 tagcaaaagc agaacaaaaa acggatgcca atggtcaaac aacttttgaa ggacttgctt
     6541 taaaagacgg cgacaaagat aaagtctata tgtttgttga aacaagcacg ccaggcaatg
     6601 tttccgtaac gacaaaggcc gctccaatcg ttttagcaat gccaatctat acgtttaaag
     6661 atggcaaata ttcagataca atcaacacca acgttcaagt ctatccaaag aacgaaacca
     6721 agactgataa aaaagaagtt gcgaatttag ataagttcac tgaagttaag gatgctgatg
     6781 gaaatgtttt atatcataac cttacaactg gcgatgaaat cgaatataaa ttaactttaa
     6841 atattcctgc ggacattctg gaagatggcg tcacttactc tgtaactgat acgccaactg
     6901 ctggacttgc ttatgtaaaa gattcttttg cagcaactgg tttagtagct ggaactgact
     6961 atgaattagc cgaagattct gcaactggcg gatttactgt tactttgaaa caaagtgaaa
     7021 atgtaggaaa attagctggt agtcaattga ttgctactta caaaatgaaa ttaactgctg
     7081 aagtaaatcc tgacgattta gtaaacaata gtgcccaagt aacaattggt aacaaccctc
     7141 aagataaaat tacacctcca acacaatttg gtacaggtgg ttataaattc gtcaaaaaag
     7201 attcgcaatc tggtgcaacc ttatctggtg cggaatttgt cgtaaaacaa ggctctaact
     7261 ttgcaatatt tgaagatgct aaaaacacta aaggtgaata tatctttaaa gaatggacga
     7321 ctgatgaagc aaaagcaacg aaaatcattt ctgacgacaa aggtgagttg aaagtaattg
     7381 gtttgaaaaa tggtgactat caattagaag aaaaagcgac ttcaagtgat aaatatgtgt
     7441 tacttgatga agatgtcgat ttcactgttg aacacggtca atatggtagt caagaactaa
     7501 agtctgttct taacacgcct aaaggtctgc ttccatcaac aggtggtaac gggatctatg
     7561 ccttcttact tatcggtgct gctcttatga tcggtgctta cgcttggttc aagaaatcta
     7621 aaacacaagc tgaagtctaa gatatagttt taaaatagca aaaggcagct tcatttcttg
     7681 aagttgcctt ttctttcttt taaataggga gaaggaggtg caagcatgga tcagcgccaa
     7741 aaaaatgaac ggatcaattt gattttaaaa ctgctaatgg cgattttatt tacgaccggt
     7801 gccattattt tcagctatcc ctttttgtcc aatgcggtga attcctatta tgaccaaaag
     7861 atgatggaaa aaaacttggc tgagatggcc gcaacaaata ccaaagaaca agcaaaaagg
     7921 caccaagaaa tggccgaaaa aaataaagag ctagctgaaa gtaagaacat gaccaatatt
     7981 cctggcatgg gactggtaga agacccgttt gaaaatgcgg tcgatgatgc caaagatccg
     8041 ggtaaagcct attatgaaga gcataccgtg ggtgctatct atattccaaa aatttcggtc
     8101 agcttacctt tatttgatga aaccaatgct gctcttttgg aaaaaggcgc gacgatttta
     8161 caaggaacgt cttatccgat cggtggcgat agtacccatt cggtgatctc aggccacagt
     8221 ggcttgacgg aacgtaaact ttttacagat ttagaaaagt tggtgattgg cgatgatttt
     8281 tatttgacca ttgctgggga aaaattggct tatgcggtcg atgacatcca gatcgtttta
     8341 ccgtcggata tcgacaaagt ggtcatccaa ccggggcggg acttggtgac cttattgact
     8401 tgtacacctt atggcatcaa tacccatcgt ttattagtca ctggacaccg tgtgccttat
     8461 gtggaggaaa tggcggagga agtgaccagt accaaaaaag cggtcgaacg gcgttttcgc
     8521 ttgtatttac tactgatccc gcttttcttt gccatggttt tctattggat gtatcgcaag
     8581 ttcgtctatt atcaaagtgg caaacacagt tatgactttt gtttttactt attggaaaat
     8641 ggtcaaccca aagcaggcgt gacttttacc ttagtccgta aaaaacgctg ggcaacagat
     8701 gtcactagcc aaccagttgc tgtaagccag gtggatggat gggtgtcttt ccctgagatc
     8761 agagggggtc gttattatgc caaggcgatc gatgggtcga caaaaccagt taagggcaag
     8821 gtccgccgtt taaaagatcg gcagtttgtt ttaagccgcg tcacgaagaa aaagcacggt
     8881 aagaaagtta cttattatct ggagaatgga gcgaaaaaat gaagaaaaat aggcaagtga
     8941 tctcgcaaat tgcgatcatc ctcattttta tggtcggcat cttgaccatg ctctatccct
     9001 tttatgtcga tgcgttgaat aatgtgatcg atcaagtgcg cgtcgatcgc tatttgaagg
     9061 aaagccagaa agaatttgaa gccgaacgca agcgactggc ggaagaaaat agtaaattga
     9121 gcgaaagtgg gttagctccg ggtgctgatc cgtttgcgaa tccgaatggc ggtacggttt
     9181 cagctgctta ttacaaaaaa catttgattg gaaccatcaa tcttcctgat ttggccattg
     9241 agttaccgct gtttgatacg accaatgatg atttattgga acaaggtgcg acggtcctag
     9301 atggcacgtc ctttcctgtt ggtggcgcaa gtacccatgc ggtgatctcg gctcatcgtg
     9361 gcttgccaga acgggaactc ttcaccaatc tgccggagct taaaaacggt gatatttttc
     9421 tgctaaatgt cttaggggaa accttggctt atgaagtgtt tgacagccaa gtcgtgacgc
     9481 cagatcagac ttcggtttta aagatcgaac caggccaaga cttggtgacg ctcatgacct
     9541 gtacccctta tatgatcaat agtcaccgtt tgttagtcac aggaaaacgc gtgccatata
     9601 caccggctgc cgagaaaaaa caagtcaaag gcgatcgttt tcgtaagttg aaacaaatcg
     9661 ctatcttggc ggggacggcc ctgttgatct tagccgctat ttatcaattg tatcatgtga
     9721 tcgcccgtta ccgactgcgg aaagtgcgtt ttgatttcac agtttgctta gaaggcgtgg
     9781 cagaacatac gccaatcgca ctctatgata aaaaagggaa aaaagccctg cggcgtaatg
     9841 gaaaagccta tcaagaacta acagatcaaa ccggacaagt cacttttacc gatctaccag
     9901 gggattgcta tcgtttgaaa ttgggcaaga gttggttggt gcagtttggt ttgaagaaaa
     9961 aaaagaggcc atccaagatt tggaagataa ataagaaaaa agttatgtta aaagaagaaa
    10021 gaatgctaga agtcaaataa aaaatgctca tgttatcaaa tgatttaaat ccataagata
    10081 cacgtttcat tgtttaatat gggcattctt agcttctatt ttgtcattgg tatggggata
    10141 aatcaatgca cttcgtatac cttcgttata tttgagtaaa ttttgtagtt ttttctaaat
    10201 tcttcgtcta aactttctgt aagaagtggg aatttaggtg cacggaaact acaccaagtt
    10261 ttttaatatt ccgtctgttt ttagttaaga aacgccaatt tactttcagt ttctgtgctt
    10321 catttttgag cccttttaat tgcagctttt tcatcattct tacacgaaag gcttgaaacg
    10381 gatgttccag tgacctcgtt tagagcgtac atttattcaa gaaagtttaa ataagatatc
    10441 aaaatggccg aaaaaagaca cacaactcga tttatttttt agggtgaagg agagagtagc
    10501 acgaaaactt ttagttggct tggactgaac gaagtgaggg aaaggctact aaaacgtcga
    10561 ggggcagtga gagcgaagcg aacacttgat cttttaagtt gctatcattt ataggtcaat
    10621 agagtatact ctgttgggtg ttgaactata attagaatat gtgtattact ttgaggtcat
    10681 caatattagg cataaggggt tattttataa ctgtgaactt gtagtataat ataagtaaaa
    10741 tatatatttg ggagaataca atgtcaaagg ataacaaaga tgatgattta gtaaaaaata
    10801 ttagaaaata tgcgactacg aaaagattga attttttgtt aggatcaggg gtttcatatc
    10861 cagctattcc gttaatggga agtatagagg gtaaaagtga agaagaaaaa aatggaaaat
    10921 tattagaaaa agtaaaatta gtaagcgata aattagttac aaatgaattc tgtaatgata
    10981 ctgatatata ttatacacta agaatgtata gagaatttat tttaaatatt attggtattt
    11041 tacatctatc aaattctaga caaattcctc gaacagccaa tatttttaca acaaattatg
    11101 atttgtttat tgaaaaagca acagataaag ttctaaaaaa ctttaaattt gtgtttaatg
    11161 atggggcaag tggatatttc gatagaaaat tggaaagtac taattataat aggacagtat
    11221 cttataaggg gttaaatgac aactatacaa atgagttacc ttctctaact ttaataaaac
    11281 cgcatggttc agtaaattgg gaaaaaaatg aagagtttct gtatattaga aatcatgtca
    11341 tagcaaatcc ctgtgttgta aaaccaactg gaagagaaga agaagaaaca tttttaagta
    11401 atcattttca tgaaatgctg cgtatatttc aacttgaatt agataaacca caaactatat
    11461 tatttgtaat aggtttttct tttcaagata aacacattgc aaaaatgctt aaacgtgcgt
    11521 tgcagaatcc agagttaatg acgtatattt ttgcatttga tgaggttgat aaagataaaa
    11581 taacaagcaa cttatcgcat gaagttggtc aatataattt gaatatattg atccctaaag
    11641 atttttcgga aaatcataag caaaaaaatg ataaaggagc ggaatttttc acattaaaaa
    11701 atctaaattc tatcctaaat aatgtaacga taggagatag taagtatgac taaccccagt
    11761 aaaaagttag gagtaattac tgcagtggat ggagatatcg ctcaagtagg gatgtataat
    11821 atgtctaatg attctgaatt tttctggtat ggagagacat taataggtcc aaaaattggt
    11881 gcttatctta cgataaacca aaatgataat aaaattattg ctactgtaat caatgaaaaa
    11941 ataattgatc aacaaaactc aataaaaagt gaagagtttg ataacagata ttcaaagcaa
    12001 tcaataaaca gaattatttc tttgaaaaca aagggcgtaa tcgaaaacga taaatttcaa
    12061 gtaaccagtc aatatgttcc catgattgga aatgaagtct cactaacaaa tatggaagat
    12121 ttaaaaatta tttatggtat taacaatgca aaagattcta ttaaaattgg atattctatt
    12181 ttagaaaaac aacctatcag tttatcaata aataaatttt ttgcttctca tatcggtata
    12241 tttggtaata caggaagtgg taaatctaat acactacaca aattgtactt agaattgttt
    12301 aaatcagagt actatgaaaa aattgtagaa aaatctcaat tttttgtgat agattttaat
    12361 ggtgagtata tttcttctaa aacaaatgaa aaaactcaaa aaggtatatt tggagttcac
    12421 aaagataata gaacactttt taaaataaat actagaaacg aagacaaaag ttcaaagatt
    12481 ccagtaaaaa aagagtatct gtttgatgca gatattttat caatattatt tgatgctcgt
    12541 tctgcaacgc aagtaccttt tttaagaagt gcagttagag aatttatgaa aaaacaaaac
    12601 gaaccctttt tcgattttgg atcatatgtt acaggaacgc taaaaaaaat attaacatca
    12661 ggactttcgg tgaaccaaga tagtttacaa gattggttag atatagcaaa aaagtatttg
    12721 aagagagatt tagagtttaa atatttagat cagttagtcc aatttaataa tggagacttt
    12781 aagattaatt cattagatat ctggttcagt aaaggtgttg aaaccaatat ttcagatgat
    12841 atattgactc ggtctggaat aaataatatt tctgttatgt taaaggagta ctttgataat
    12901 aataaagata ctcctttaca acaattgagg atatttctag attttcaaaa agtacatcgg
    12961 acagcatggg gaaaaattaa tagagagcat ttaaatcctc tatttaatag gattaattct
    13021 tctttagaaa gtttagaaaa agtaatagag ataaaagaag atgctatagg gtgctataaa
    13081 acattaaata ttatttctct tgttcatgct aatcaagaaa ttactcgttt agtaccaatg
    13141 ttattgtcta aaatgattta tgatgaacaa aaatcaaaaa ctgcaggaaa gaaagttagt
    13201 ggaacaaagc atttaataat tgatgaagct cacaatatat taaattcgga gtataaaaat
    13261 aatggagata gctggcaaga ctatagatta tcagtatttg aggaaattat aaaagaagga
    13321 agaaaatttg gcttttattt aacattatca agtcaaagac cagctgatat ttcgcctacg
    13381 attctttcgc aaacacataa ttatttaatt catcgtttag taaatgaaaa tgatctacgc
    13441 atgctagaaa agacaatgcc aacccttgat aaaacatctt acaattttat tcctagttta
    13501 ggaaagggag aagcaattat aacaggaagt gctttaagca ttcctgtatt agtgaaaata
    13561 gataaagaaa cagaccttag acctagtagc gatgatataa atcttacgag cttatggaat
    13621 gattaaatat cattagtatt caatttatac tgtattaagt atttagttca ttttttattc
    13681 tatacacagt ttgtctcgta acattatatt ccttagagat ttttgaaata gcaacgccat
    13741 tctcaagatc ctcaacgatg tttttataaa caaggcgacg ttggggatct tttgcgttcg
    13801 cactataaag cttaggtcga cctttataca caccattagc tttggcaatt ttaattcctt
    13861 gtgcttgtcg acgtttggat tcagtacgtt cttgctcggc aatcatagct aaaatttgaa
    13921 tgatcaaatc tttaatgaat ttatccagga gaggatttcc aattgcttca gccatgatcg
    13981 gtagactggt gatgatcagc tgcacgtttt tcttctttag gtaattgact gaagcaatga
    14041 tttcgtcgta atttcttcca agtcggtcga ttgcttcgac aataaaaata tcttggtctc
    14101 ggacaaactc taaagcttcc tggaaaatcg gtcgatgagt aatcgttgct ccagattgtt
    14161 tctcgatgaa aattttttct gcgccgaact ttttcatttc ttcaatttgg cgttgctcat
    14221 tttgatcaat cgacgaaact cgaatataag caattttcaa aatttttacc tacttcctca
    14281 aactatttaa aatacgccct aatctgtcac ttttctattt aaatggcata aatttttctg
    14341 attatttggc atacctattt ctacttaacg agagattaat tatgatataa ttagggacga
    14401 ataactatga atttaatatg aaaataaaga aacttacagt taaggaagaa aatgatgagt
    14461 gagaatgtat attatagtgc caaagaattt tatgctaaaa tcaaccaaga tttgactatc
    14521 cgcagagaag atatggttat tttagtttgc tcaatcgtta tagcttgtat tggcttgaat
    14581 atggatacta ctccagttgt tattggagca atgcttgtat cccccctaat gacacctatc
    14641 caaggtatcg ggatggggtt gtctcttttt gaccaacaaa tgctaaaaaa agcgttaaaa
    14701 atccttttag tacaaataat ggtttctata gtgacagcaa gtatttattt ttttatttct
    14761 cctatttctt atgcaagtaa tgaaattctt gcacgaacac aaccaacaat ttgggacgtg
    14821 attattgctt tctttggagg aattgctggg gtcataggtt ctcgaaaaaa agcaatgaat
    14881 aatattgttg ccggtgtcgc aattgctgca gctttaatgc cacctttgtg tacggtaggt
    14941 tatgctattg ctttaaaaaa aatgccctat tttttaggag caggatatct atttttaatc
    15001 aattgttttt tcattattat cgctacgttc attggtgttc aagtcatgcg tattcctaaa
    15061 agtgtaaagg tggatagtga agagaagagt aagatgaatg tggttattgt tatactgagt
    15121 attgttattc tgatcccaag tataatttct gcctcacaac ttgttggaaa aagtattatt
    15181 gagaatggat taagacgaat gctctcagaa gaattgggta acaacgtcat tgtcattaac
    15241 aaatcgattg atcaagaaaa taaaattatt tatttaacaa cttcaggtga gaaaatatct
    15301 gatacaagaa taaaaaaaat tgaagaaagt ttaccaatgt ataacttaaa aggaatgtcc
    15361 ttggaaataa gtcagattac aaacactcaa caactttctg gagaagactt agtcagactt
    15421 ttaaaggagt atgaggagtc taaaaagagt aactctatag agaaaacaaa aagagtgaat
    15481 tctacagaag attcaaataa tgagtaaatg gaaagtagtt agaaaatgaa ctctgtatcg
    15541 gagttgagcg cggttgatat gaatttttat atctgtgaag attgcgtatt gcctgataga
    15601 atgaaccaaa gtattgagaa tctactgaca ggatctattg cttcagattt tcaaaattcg
    15661 atagaataag aaattagtta gctagcttaa atttaataaa tagaaagact gattgtcagt
    15721 agttcgtcat aaaatttata aaacctgaac aacctttaaa gaggatgttc aggttttatt
    15781 atagtgaacc aaaccgcttt tgtcatagtc acgagtgttt gcaactcatc ccgtgcagca
    15841 agcacccgat tacggttgag gtctgtaaaa ccgtcaatgg gaaagaagac agccgttgtt
    15901 gtcggagtga tttttccgtg ttcacaaaat caggcgtttc tgaacagtct atttttttat
    15961 cttatttcta taattttgat tctattatgt gttcacaaac ccatatcaaa atctgtgttc
    16021 atttatacta ttggtataaa gttatgttac aataaaatta atgaaggagt gatttttttg
    16081 aaaataggat acgcccgggt atctactggt ttacaaaatt tggatttaca agaagacagc
    16141 ctaaataaat ttggttgtga aaaaattttt accgatcata tgagtggagc aaaaagtaat
    16201 cgaccaggat tagaaatggc gattgatttt gttcgctctg gcgatacact tgttgtttgg
    16261 cgcttagatc gtttaggtag aaatatggaa gatttgattt caatcgtcaa tcgactgaat
    16321 gagcgaggtg ttagttttca tagtcttcaa gaaaatatta cgatggataa atctagttcg
    16381 actggtcagc tcatgtttca tttgtttgca gcattcgcag aatttgaacg caacctgatt
    16441 ttagaaagat ccgcagcagg acgagcagca gctcgagcaa gagggcgatt tggaggacgt
    16501 cctgaaaaat taaaagcaca agacttagaa ttattaaaga ctctagttga tagtggaaca
    16561 cctattaaaa cgattgccga acgttggaat gtttctcgaa caacgattta tcgttattta
    16621 gataaaatgg agggaaaaga tggaaaaaca aacactcact agtttttcag aacagcaaag
    16681 aatagctgcg atgaaaaaat ataaaattat tgagccttat cttaataaac aaaaaacgat
    16741 aaaagaaata gctattaaaa ataaagcacc tactcgtaca ctctatcgct gggtacaaaa
    16801 atatgaacat gatggtctag ttggtttaat tagaaagact cgaactgatt tttagcaaat
    16861 tagggtttca gaagaagttc gacaaaaaat agaagaattg gtattgagat acaaaaaaat
    16921 aagtactaag acattatctc gaaaaattgt ttcctatcat atttagtgga attgttgtct
    16981 ttttatttgt aagaggaaat ctttcttttt cgtttagaga tattttaatg cctttcatag
    17041 gtttatttgc tttatttggt atttatgaaa gtgcgaatca atcaagaaaa agaaaaataa
    17101 agaaagaaat ggaaagaatg aaagccaaag atcatattaa gcagtaataa aaaaatctag
    17161 taaggaggct ttcttatgag tacggttatt ttagctgaaa aaccaagcca ggcattagcc
    17221 tacgcaagtg ctttaaaaca aagcaccaaa aaagacggtt attttgagat caaagaccca
    17281 ctatttacag atgaaacgtt tatcaccttt ggttttgggc atttagtcga attagcagaa
    17341 ccaggtcaat ataacgaaaa gtggcagaac tggaaacttg aatctttgcc gatttttcct
    17401 gatcgatacg attttgaagt tgcaaaagat aagggaaagc agtttaaaat tgttgcagaa
    17461 cttctcaaaa aggcaaatac aattattgtt gcaacagata gcgacagaga aggtgaaaat
    17521 atcgcctggt cgattatcca taaagcaaat gccttttcaa aagataaaac atttaaaaga
    17581 ctatggatca atagcttaga aaaagatgtg atccgaagcg gttttcaaaa tttgcaacca
    17641 ggaatgaatt actatccctt ttatcaagaa gcgcaaacac gccaaattgc cgattggttg
    17701 atcggcatga acgcaagccc tttgtatacg ttaaatttac aacaaaaagg cgtacaaggt
    17761 acattttctt taggacgtgt acaaacaccg actttatatc tcatttatca acgccaggaa
    17821 gccatagaga attttaaaaa agaacctttt tttgaggtgg aagctagtat aaaagtaaac
    17881 caagggtcat ttaagggcgt tctaagcccc acacagcgat ttaagaccca agaggaactt
    17941 ttatcctttg tttcttcaaa tcacgctaaa ataggcaatc aagagggcag aatcgctgac
    18001 gtgcaaacca aagagaaaaa aacgaatagt cctagtctgt tttctttaag tagtttgcag
    18061 tcaaaagtca atcagcttta taaagcgaca gcgagccaaa ctttaaaagc tatgcaagga
    18121 ctgtatgaag caaaattatt gagttatcca agaacagata caccatttat tacagagaac
    18181 gaatttgctt atttaaaagc gaattttggc aaatatagcg gttttttagg acttgatctt
    18241 gaaatggttc aaacagagcc tagaaagcgt tatgtggacg gtagtaaggt acaggaacac
    18301 cacgccatta tcccaacaaa acaagtacct accgaatctg cattagcgaa aatggacgat
    18361 ttacaacgaa aaatttatgc tttagtcgtt aaaacgaccg ttgccatgtt tttacctgat
    18421 tacttgtatg aagaaaccaa gatacaaacg aaagtagctg atttgctgtt tcaatcgatc
    18481 ggaaagacac caaaacaaga aggttggaaa attcttttca aacaacaaac caaagaagaa
    18541 aaagaggacg ttcaaacgtt acccttggtt atcattggcg aacatgccga ggttgacgtt
    18601 aagagtgccg aaaaagaaac acaaccaccg aaagctttta cagagggtac attattaact
    18661 gctatgaaaa ccgctaataa aacggttgat gatgaagaag caatcaagat tttacaagaa
    18721 gtcgagggga tcggaacaga agcgacaaga gcaagtatta ttgaagcgtt aaaacaaaaa
    18781 gaatatatcc aagtgattaa gaataagctt gttgtaactg aaaaaggaaa attattgtgc
    18841 caggcagttg aaagtcagca ccttttaacg agtgctgaaa tgacggctaa atgggaaacg
    18901 tatttaaaaa aaatcggtaa aagagaaggc aatcaagaga actttattac gaatatcaaa
    18961 aaattcattg ttcatttact ggaagctgta cctaacgata tagaaaaact aaatttttct
    19021 gattaccagg aacagaaaga aaaagaagca gaaaaaagt
//
LOCUS       DADQCX010000056        18504 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.056, whole genome shotgun sequence.
ACCESSION   DADQCX010000056 DADQCX010000000
VERSION     DADQCX010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.056"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            99..746
                     /locus_tag="J8R83_001766"
     CDS             99..746
                     /locus_tag="J8R83_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAZ9574896.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            1139..3784
                     /locus_tag="J8R83_001767"
     CDS             1139..3784
                     /locus_tag="J8R83_001767"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAZ9574897.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="J8R83_001768"
     CDS             4094..5407
                     /locus_tag="J8R83_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAZ9574898.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="J8R83_001769"
     CDS             5397..6050
                     /locus_tag="J8R83_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9574899.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /locus_tag="J8R83_001770"
     CDS             6105..6797
                     /locus_tag="J8R83_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAZ9574900.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="J8R83_001771"
     CDS             6947..7147
                     /locus_tag="J8R83_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9574901.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="J8R83_001772"
     CDS             complement(7401..9080)
                     /locus_tag="J8R83_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAZ9574902.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="J8R83_001773"
     CDS             complement(9082..9294)
                     /locus_tag="J8R83_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAZ9574903.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="J8R83_001774"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="J8R83_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAZ9574904.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="J8R83_001775"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="J8R83_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAZ9574905.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="J8R83_001776"
     CDS             13269..13466
                     /locus_tag="J8R83_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574906.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="J8R83_001777"
     CDS             13619..14104
                     /locus_tag="J8R83_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAZ9574907.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="J8R83_001778"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="J8R83_001778"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAZ9574908.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15508
                     /locus_tag="J8R83_001779"
     CDS             14981..15508
                     /locus_tag="J8R83_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAZ9574909.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15599..16336
                     /locus_tag="J8R83_001780"
     CDS             15599..16336
                     /locus_tag="J8R83_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAZ9574910.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="J8R83_001781"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="J8R83_001781"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAZ9574911.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="J8R83_001782"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="J8R83_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAZ9574912.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5984 a         3200 c         4022 g         5298 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa ttttattttt ttaa
//
LOCUS       DADQCX010000057        18170 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.057, whole genome shotgun sequence.
ACCESSION   DADQCX010000057 DADQCX010000000
VERSION     DADQCX010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.057"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(75..1583)
                     /locus_tag="J8R83_001783"
     CDS             complement(75..1583)
                     /locus_tag="J8R83_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAZ9574913.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            1742..1933
                     /locus_tag="J8R83_001784"
     CDS             1742..1933
                     /locus_tag="J8R83_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574914.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            2136..3053
                     /locus_tag="J8R83_001785"
     CDS             2136..3053
                     /locus_tag="J8R83_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAZ9574915.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            3046..4119
                     /locus_tag="J8R83_001786"
     CDS             3046..4119
                     /locus_tag="J8R83_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574916.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            4267..4785
                     /locus_tag="J8R83_001787"
     CDS             4267..4785
                     /locus_tag="J8R83_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574917.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            4766..5158
                     /locus_tag="J8R83_001788"
     CDS             4766..5158
                     /locus_tag="J8R83_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAZ9574918.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            5234..6169
                     /locus_tag="J8R83_001789"
     CDS             5234..6169
                     /locus_tag="J8R83_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAZ9574919.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            6302..7081
                     /locus_tag="J8R83_001790"
     CDS             6302..7081
                     /locus_tag="J8R83_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAZ9574920.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            7074..7391
                     /locus_tag="J8R83_001791"
     CDS             7074..7391
                     /locus_tag="J8R83_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAZ9574921.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            7635..9245
                     /locus_tag="J8R83_001792"
     CDS             7635..9245
                     /locus_tag="J8R83_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9574922.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            9402..10250
                     /locus_tag="J8R83_001793"
     CDS             9402..10250
                     /locus_tag="J8R83_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9574923.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            10481..10960
                     /locus_tag="J8R83_001794"
     CDS             10481..10960
                     /locus_tag="J8R83_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574924.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            10993..13221
                     /locus_tag="J8R83_001795"
     CDS             10993..13221
                     /locus_tag="J8R83_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAZ9574925.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            13350..14993
                     /locus_tag="J8R83_001796"
     CDS             13350..14993
                     /locus_tag="J8R83_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAZ9574926.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(15066..15611)
                     /locus_tag="J8R83_001797"
     CDS             complement(15066..15611)
                     /locus_tag="J8R83_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAZ9574927.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(15634..16119)
                     /locus_tag="J8R83_001798"
     CDS             complement(15634..16119)
                     /locus_tag="J8R83_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9574928.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(16109..16921)
                     /locus_tag="J8R83_001799"
     CDS             complement(16109..16921)
                     /locus_tag="J8R83_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAZ9574929.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(17060..>18170)
                     /locus_tag="J8R83_001800"
     CDS             complement(17060..>18170)
                     /locus_tag="J8R83_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAZ9574930.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         5907 a         3306 c         3634 g         5323 t
ORIGIN      
        1 gtaaagtcta taaaaaaacg aaactatcga ttaagctaat agtttcgttt tcaacattta
       61 taagtaaact ttttctattg gtaatataga ttttcggaag ggtagacagg tgcgcaggta
      121 atatcgattc ctagtttttt caatgtttgt tcatcatttt tattgaccat cacagtagag
      181 tgggcttgtg ctccctcaag ttcagctagt ttatcataag caacttgagc gattggattc
      241 gttactgcac tgattgataa agcgatcaag acttcattga tgcttagtgc atccaaagag
      301 gaatgaagtg tctttgattt caatccttgt attgtttcaa gaactaatgg tgacaataaa
      361 ggaatgtcat ctgcgatatg ggctaaatgt tttactgcat ttaagataac tgccgctgac
      421 gcatccatca atgaacttgt acgcccggta atgatgactt catctggtaa ttcgattgca
      481 atcacagcag aaggatcttt tgtaggactt tgcgcttgaa tcttatctgc atagtcatgg
      541 gcagggacta ccacgtttcg gtcttcagga cgtaaaccga cttcttccat aatcagtttg
      601 attcgattaa ctgcttcttc gtcgatcaat ccttttttga agtcgcattc tgtttggaaa
      661 taacgacgga tgatttcttg tttagaggct tcttggacaa cggtatcatc cacgatccca
      721 aatcctacac gattcacacc catgtcagta ggagattgat aaacagattc tttaccagta
      781 attttttcaa taatacgttt gattacagga aatgtctcaa catcccgatt atagttcaca
      841 gctactttat tgtaggcatc aaagtggaag gaatcgatca tattgacatc ttttagatcg
      901 actgtggctg cttcataagc aatgttcagc ggatgtttca acggaacatt ccatactggg
      961 aaagtttcga acttggagta accagctgca tgtccttttt ggctttcatg atacagttgg
     1021 ttcaaggaag tagcgagctt tccacttcct gggccaggag ctgtcactac aacgattggt
     1081 ttagttgttt caatatactc attttttcca aaaccatctt ctgagacgat tttttctacg
     1141 ttgactggat agtcttcgat ttctgagtgt ttatagacct tgatgtttcg tctttctagt
     1201 ttattgataa agactttcgt ggcaggctgt ccactatagc gagtgataac gacactgttg
     1261 attaataagc cataaccacg taattcatcg attaaccgca agatatccat atcataagta
     1321 atcccataat caccacggat cttattacgt tcaatatctc cagcatagac gcaaatcagt
     1381 atttcagctt gatctttcaa tttttgcagc aatttgattt tcgcatcttc ttcaaatcct
     1441 ggaagtacac gtttcgcatg cttgtcgtca actagcttcc caccaaattc taaatataat
     1501 ttgtcatagt ggttcactcg ttccaaaata tacgctgact gctcttcaat atatttttct
     1561 gaatcaaaac caattttttt cactaggttc cctccttaag tactaaagca ttttttcatt
     1621 tttttgagga ttcgtcaact ggaagagcga aattcctcaa aaaaacaaag aaaatggttt
     1681 aaaccaactt gtctagatag ttattcattg gtatgatagt ttttgataag gaaggtgcta
     1741 catgaaaaaa agacagaaaa agaaaaacgc atataaacac tatatccgtt cgatttttac
     1801 cggttatgaa agaatgcttg aagatcccga attggaacaa ttgacgttta cttatctaaa
     1861 cgaagaaacg cagctaactc gtgatgagca tcagcgcatt catttcacaa caagagatct
     1921 gcctagtaaa taaaaaataa gataaaggtc atcggattcg attctgtcct atcagatgga
     1981 aagactagtt gatcgaaaaa aaggctgtac caaattttgg tgcagcctgt tttatggagc
     2041 attgcccgct cttttttata acaatttttt acagaaaatg gtactattga agtattaata
     2101 agtgaaaaac agatgagtaa gaggaggcaa gtagtatgaa agagccagat acaaatgcaa
     2161 attatgagcc agacgaacta gaggagacga atgcggatca ggatacagga caagaatcgt
     2221 cttcttttta cgatatcaaa gaaaaagcaa gcatgaatct ttcccaatta ttagaagact
     2281 tacaggcttt tgaaaaagct gtccgcgaag aagatatccc tgagatctac cgtttataca
     2341 atggccgatt gaatgaagaa ttaaaaagaa gctcaaatga aaatcacgag atcgatcaat
     2401 tgctgatgcg taagatccat gatcgttttt tacaggaatt tccttttatg gaacaagtag
     2461 aaaacatctc gccaacgatg agctattaca aaatcggcac ttattaccat gatcggccca
     2521 cggtcggtat tgatgcaagt ctgccagaaa tttttgtttt gcctaagatc gatgaagagt
     2581 gggagaaata ttcccaaccg gagtcaacgg actatgacaa aaaaatcaat gagctagacg
     2641 caaaggtgat cactgctcag acagaaattg aacgtttaga tgaacaaata aaagaaatca
     2701 atcgacaaat gactgatttg aacgacaata aaggattctt gaatcgtaaa aaaatcgagg
     2761 aagaaattca agaattagag aagaagaagc aagtactatc taatgaaaaa ttaggctggc
     2821 ttccttatat tgagacgcct gaaacaatcc agcagcaaaa agaagcattg aagcaagaag
     2881 caagagcaga ccagcttcgt gcagccatcg tagaaaaaga acaaaggcaa atcagacgct
     2941 atttcggtag caaagaggga ttcggtcaag caatccatga attcttgatg aattatcttg
     3001 gcaatgagaa tcctaataat caatctaatg aaggaggttc cgagtatgaa tgaacacgat
     3061 gaagcagaat ggacaaaaaa tgaagaacaa acagaagatc atgaagaaac gaacacttca
     3121 ttggaagaac aaacaagtaa tcctctggat gacacagaag aaatccctat gctagaggaa
     3181 acaaaaatac acgaaaaaga aaaagtaact ccgacgaata cgaatactgc agaaaacacc
     3241 catgcttacg aaataactga aaatcccggg tatttagaag gaaaagagca agatcatcaa
     3301 gatatcgtca gtttgattga aacagcggaa gcagaattag cggatttacg tatgagaaaa
     3361 gatttgatcg aatcagattt tccacaatta ttagaatcat atgatcgttt tatattgaat
     3421 gaagaaccaa tctccacgat cggaaagaca agcctgatcg aatacttcac gtatgaatta
     3481 ctgaaaccgt tgaatgatat tggtctggaa cggtcaaatt cagcttatga cacatggaaa
     3541 acaagacatt tttcgatcaa ttatacgttg aatggacaaa acgaattagt cttttccttt
     3601 gtattaccga ccatcgatca acgataccaa gtggaatcga tgagtctcct aaacgtatca
     3661 ccagagacaa tggaaatcaa tgtccaagat gaccgggtgc tttctttgat ccgacactgg
     3721 tcagtggatc gagtattctc tgcagggcag atcacgatat tcaatcacaa attgaatcaa
     3781 ttattagccc atgcaagaac acttggtttt accgttaatc agacattact agacaatacg
     3841 aagccacttc gtttgaatct tcagagcgaa tttgaattga cgaatgaagt attggatgat
     3901 atttttatcg tggcaatgaa aaatccatcc tacgatatgg aaaagatcaa cgaaactact
     3961 tatcaagtac gattagataa aggacagtct ttaacgataa caacaaacga aaaagatcaa
     4021 acagtcttgt cgatctcatc tggagactac ccacgatctg tcattgattt ctttatcaat
     4081 tacgaattct tggtcccatt aatggtgaga aagtcctgat tggataagtt ggattaccag
     4141 atgtcattca gataattctg ttccaaagga cttgcggcag ttatccagaa taattgtcac
     4201 aagtcttttc tgtatgtact aaatggacgt gaataacttg ctgatgaagg agggatttca
     4261 ttaggaatgt ccacaaataa aatagcacag cttagcttat tgtctgctgc ttgtgtagca
     4321 ggtaggatcg cttttcaatt tattccgaat ttccagccaa tgactgctat ttttttattt
     4381 atagtacttt acttaagctt aaaagatgcg ttaattgtca tgagtctttc tattgcgatc
     4441 agcagttttt attttggtgt tggaccatgg gtcatcggcc aatggatcag ctatactgtt
     4501 gttctgagtt tgttttcaat cgtctgcttg agaaaaacag tgcaaaggaa tctatggtta
     4561 aagggagtct gtttttttct ggcgggcatg gtttacggaa taggtatgac cgtttttgat
     4621 acgctgttat atcgtttgcc tcaaccttgg atctattacc ttcaaggggt gtcgtttgat
     4681 ttgatgcaca gtataggcaa tgttgtgttc tttcttgttt ttctgccagt cgtcaaacgt
     4741 ttttacaatc attcaggagg aaaaaatgaa aaaaataatt tatagtttgc ttgcaatgag
     4801 tgtcagtata ctcattttga caagttgcag tacaacctat acacaatcgg cttccaacca
     4861 aaaggaggaa gtaaaaacat cgcaaaaagc aacaatcacg ttacaagaaa atggtcaaaa
     4921 cttttcggaa aaagaagtgt tcttcaaaaa aggcgatgat ttactgagta ttttgaaacg
     4981 aaattttgaa gtcaaagaag ataacggctt catcacttcg cttgaagggc actcacagga
     5041 tgagaaaaat caactctatt ggatgtttac tgtggacggg aaaagtgcta ctactggtgc
     5101 caaagagatc aaattgaatg atggacaatc ggtcattttc aatttgtcta aactataagt
     5161 ttcataaaaa actgttaaag ggcgaatatt gccataattc agtgagttca gttgatgaaa
     5221 gaaggaaaat aacatggaaa attttaaaaa aagcggaatg ttttccgtaa ttgctgctct
     5281 aggggctaat attctagttg ctatcagcaa atttgtcggc tatgcaatca gtggcagtgc
     5341 cgccatgcta aacgaaagca tccacagtat cgttgattgc agcaatcaga ttttgctgtt
     5401 attcggtgat aaacaagcca ataaaggaca gagcgagttg catcaatttg gtgaaggacg
     5461 agcaaaatac tttttcagta caatcgtcgc aatgatgctt ttcttcggcg gtggggcact
     5521 tggggtgatg gaagcttttg aaaagttgac gcatccatcc catgaagtgg gtaatccgat
     5581 cattgttata gcaatactgt tatttggttt ggtaatcgaa ggaagttcgt tacgcgtggc
     5641 aatgaaagaa atcaaagaat tgaatactga aaaactttcc acgatgcgct ttttgcgcga
     5701 aagtcgacac agtgaaatac tgattatttt tacggaagac ttgtgtgctg taatcggttt
     5761 ggtcttggct ttagcaggaa caatattgac ttatgcaacc gggattgctg catttgatgc
     5821 gatcagcgga ttgctgatcg gtttcttgct gatgggagcc gccattttcc tagcaaaaga
     5881 attttatagt ctgatcatcg gtgaaagcgt gacagcaagc gatttatcaa aaatcaagtt
     5941 agcttttgaa cgtcctgaga tcagtcggct gatcgatata aaaacagttc atttaagtcc
     6001 aacggagatt ttagttgcag caaaagcaga tatcgttggt aacaaagaga atgaagctta
     6061 ctcggtcatc aatgatattg aaaaaaatat gcgtcagtct cttcctgaca agaagatgta
     6121 tatatacatt gaaacagata aatatgaccc aaattattct cgtaaataaa acgtttattc
     6181 atgaattgaa gcaaaaatga gaaaaatata atcttgtttt taaataaaac ggctacaatt
     6241 tagcgaattt atgttacaat gagtccgctg tttatttgtt gtaattaaag gagatatttt
     6301 aatgaacaaa aagaaaagtg cgccatggct tcaagctttg catgcagtga tgccactttg
     6361 tataagctat ataccagtag gattagcttg cggagtattg ttgcaaaaag ttggatttga
     6421 tcctctctta tcaggactgt tatcgattct ggtcttttcc ggtggcgcgc agtttttagt
     6481 tgcatctatg cttacgacgc aagcatcatt tgcaacgaca ttattgatgg ttttcttttt
     6541 agaattacgc tatacattat taggagcaag tcttgccggt tttatgaaaa aagaaaagcg
     6601 gacgtttttg gctgtctttt ctcaatcact gaatgatgaa aactatgcgg tgaactactt
     6661 aaagttttca actgaccctt cctggaataa aagaaaggct ttatatgtca attggttctc
     6721 aatgactgca tgggccggta gcaatatgat cggtaatttt ttcggctcgg tgattcgagt
     6781 agatgctgac cttgtccatt ttgctttgac ggccatgttc attttcatgt ttatcatgca
     6841 gatgaaaagc gcactactga tctttacagg tttattctca ggcgtattag gggtcgtatt
     6901 catggtatta ttccaaaata ctttcggatt gattgcagca acagtcattg cttcatttgc
     6961 cggatttatg ctggagaagg cattcaaaaa agaaaaagct aagaaactaa gagaccgcgg
     7021 taaagatgtc aatgagccgc tcttcaactt cccggaacag gaggccaatc accatgacta
     7081 aactatattt gctactttta gttgcttgtc tgttcatcgt ggcatatatc ccgcgcttgt
     7141 tcccgatgct ttattttact catcgaaaag tgccatcctg gttcagtgac tggatgaaat
     7201 atgtaccggt ggcattattt gcggcgttag cttttaaaga tgttttcatt actcatgaac
     7261 atctggatat tgcttggaat atcaaaatag ctgcaatgat tctagtagca ggcgtggctt
     7321 acaaaacacg ttcgatggcg ttgtcagttt tgacaggact tgcgtctgtc tttttgctgt
     7381 ctatgcttta aactgtttta ttttattaaa aacagagatt gcgacataag ttgttcaaac
     7441 tgatctatcc gaactgcatt tgcaacagtc aattctggat gcaagtttat tcgtagggat
     7501 aaaaaagatt agtgttggct tatgatgcaa gctctttttt attttaggaa ttagagaggg
     7561 atttgtcctt ctatgatttt ttgctataat agggaagatg tttattttat gaaagaatag
     7621 ttgagggaat ttaaatgaat aaaaaattga tgcaaggaac attttggcta acctttgcta
     7681 atcttctatg taaagtttta ggggtagtct atttgattcc ctggctaagt atgatgggga
     7741 acaatcaaga tggtatgctt gctacgacat tgtataatgt tggctatctt ccttatggat
     7801 tgttcctgat gcttggtaca gtcggatttc caaatgcgat tgcaaaaaaa gtagctgtag
     7861 ccacaaaaga aggagataac gctgcttgtc ggctgatttt tagaagtacg atcaatatca
     7921 tgtttgtcat cggtatcgcc tctgctgcac tgatgtattt atttgctcct ttactagccg
     7981 gaatcagtcc gattgctaac gttaataatg ggatactagc tatcagaagt ttatgcccat
     8041 ctttgattgc tatcccaatt cttagtgcaa tgagaggata tttccaagga aaaaatgatc
     8101 tgcggcctta tggaacttct ttgattatcg aacaggctgt gcgagtgatc gttatcttgg
     8161 ctggtactta ttacttgcgc gtattgactg acggaaccat attagaagct gtattgatca
     8221 gtacagtcgc ttctttcttc ggtgggttag ctgcgattat ccatatgtat atcgtcggac
     8281 gcagaaaaga cttcttcgaa cttaaagatt ttttgatttc cagccgttat ttcgaaagag
     8341 aaaaccgatc tgcctctgtc tctatcattc gggaaacact accgtttatt tttgtcggct
     8401 cagtcattac tatcgttcaa atgatcgacc aagtaacgat gaaaccactg cttcactttt
     8461 tccgtccaga gatcgcagat cagcaactgg aattcttatt cagccgtgct tctgtcaatc
     8521 caaataaatt gacattgatc ctgatctcca tggtaggaac agtagctata agcagcttgc
     8581 caatattaag cacgatgaag aaaaaagatc ggatacaaat cgaaaaaaca gtaggagata
     8641 gtttttcgat tgcgttattg attcttcttc cttcattgac tggaatgtct ttattagctg
     8701 gaccactata cacattgttt tttggctatg atcctgaaag tgtcggatat ttccaaatgg
     8761 ctttgctagc ttctttgttt ttctctttat tcacgatcct atctacgatg cttcaatctt
     8821 tgaatcacca tcgttttgcg atccgattaa ctgtagaagc aattatcctg aaagtcatct
     8881 tccaagtaat cggattagga ttagttggcg gatacgggat gagcttatca aatggcttag
     8941 cattcggtat tgtctttgtt cgcggctatc actttatgtg caaagaatac cgaatagcac
     9001 ctttagcaaa gatcagcaat tttttcttaa aaactttccg ctccaccctg attatgcttg
     9061 cagtatgttt tgccgttttc tttttgctga atcagcgatt gtcaatggaa tcaaaaagct
     9121 atgcaatgat ttattgtgtg gctgtaggaa gtattggcgg cttagtattt ttattttctc
     9181 aattcggaaa aaatgggttt cgaatgttga aaaatgttaa acatcatagc agaagcaaag
     9241 aataggttaa ctaatcgttt tttgctgtca cttgaaaaac ggcaactcgt atgattacgc
     9301 ttgtcgtttt tctattttcc aattttagtt tcatatctaa tcttacttat gatatagtta
     9361 taaggtctgg aaaaattctt tgaaacgagg aaattaaaca catgaaactt gcagtagtta
     9421 cagatagttc ggcatatctg ccggaacgta tcaagaacca tcccgactta ttcgttattc
     9481 caatcccttt gattatggat gggaaaattt ataacgaagg aatcgatatc gaagcggatg
     9541 aatattatgg acttttaaaa aacagtaaag attttcctac tacttcacaa cctgtcgtag
     9601 gggaagtttt gggtttatat gaggaattga aagagaaagg gtatgacacg attttaagta
     9661 tccatctttc ttcagggatt tctggctttg tcaacacatt atttgcgatg aaagatgaca
     9721 tcagcggagt aacggtcatt ccttatgact ctaagatcac tagtatgccg atgggacaca
     9781 tggtagaagc tgccttagac ttaaatgatg aaggtcagtc ccttgatgaa atacttgcac
     9841 atatcgatcg aatccgagat aatacctacg cttatctgat tgtagatgat ttgaacaatt
     9901 tagtacgagg aggacgtttg acaaatggtg cagcgctgat tggcagctta ttaaaaatca
     9961 aaccgatcct gacattttct gaagggaaaa ttgttttatt cgaaaaaatc cgttcaagta
    10021 aaaaagcatt tgctcgagct gaagaaatta ttggtagaag aaataacgaa atacaaccgc
    10081 cagtcaaact ttacgtgata catgcaaata atttagaagt agcgattgcg gagaaagaga
    10141 aattgcagaa aaaatatcca aatgcagaaa tcgaaattgg tcatttcgga ccagtcattg
    10201 gtacacattt aggtgaaaaa gccatcggca ttgccatttc agcgcaataa ttccttttat
    10261 tcaaaaaaca taccaaaaat attccaacat catcttggac tttctacatg ttactaatga
    10321 gcgtgtaaaa gaacgagatg gtgtttttat ttctatcaat gaagctcttt ttctttgcaa
    10381 tcctcacttc aatcctctat aatgtcgcat atagtttagt aaatgagtaa actactaatt
    10441 tacttattta ctaaaaataa aaggatgagg agttaaaata atggaaatac caacaaattt
    10501 aaaacataaa ccagtaatcg ttgtagaaga ctatgataaa gttgatggaa gaaatgcatt
    10561 aaatacggat gcaaaagggc tttcactggg ccttgctcag tggaatgatc gtggaaaagt
    10621 cgatatctca ggcaaggtat ggcgacatac tggagaaaaa tggtcacgac agtcggaaga
    10681 attaccaatc acacgtattt tagatttagc gatcttagct gcacaaggaa gtttatactt
    10741 ccaagatgct tatcgttatg aaaaatttta tgatccagaa aatccagtcg tagacatcat
    10801 tggattacaa gggaaccgaa tgacggtaga agtagatacc aaaaatccaa agatcgatga
    10861 agacatcatt ttgtattacg atacactaca aaaagacgga gaactgattg gggaacgatt
    10921 ccgtatttta aaacgtcttt tagatgagct aggatattaa tagacagaga tgatcaaaag
    10981 gggaagagaa gcatggagaa tttctcacta acagaaaacc gaaccttttc acggctagaa
    11041 aagcaaatga tctggaagaa accgaaaagc catcggacaa gtgcagaaga atggcggatc
    11101 gcctccgaaa tcaaagggaa ttggcaagat cctgaaatga aaatcagtaa cgtacttttg
    11161 gaaggagatg ccgggtcggg gaagacacaa ttagccaaag cactatctgc tgatctgcaa
    11221 cttccctata caaaagtgac ctgttttgca gatatggaca aatcagatgt tttcggagcc
    11281 ttattacctg tagtagattc taataaggaa caagaccaag aattactaga agctatttac
    11341 caaacagata cacttgaagc tgtactgaca ctgatccaga accattacgg cattgatcct
    11401 ttttctgcta aagaaaaatt agcagagcta gttcaaagga tcgaagctga ttatccagat
    11461 gcaatccatt acagctatta cccttctgaa atcgttcgag cgattgaaaa aggatattta
    11521 ttagagattc aagagccgac tgtcatccga gatgcctctg ttcttgtggc acttaactca
    11581 gcgctcgaac caaatgggat gttgaattta ccgacaggaa tcattcgtcg ccatccagat
    11641 tgcgtcattg tgatcactac aaatcgaaat taccaaggaa atcgcccatt aaatgaatct
    11701 ttaagagatc ggatgcaaca tgcggaaaaa atggatcttc ctgccttaga agtcatggca
    11761 gaacgtgcga tggcgaaaac tatgatccaa aaacaagaac ttctcttaaa gatggcagag
    11821 attatccgtt tgttggatga aactgcaaaa gctaacgcca tcaaaggtgt agcaggaatg
    11881 cgttcttatt tttattgggc aaatacctat aagcaaggac aagatttact ccagtcgatt
    11941 tatccaaaag ttttgtataa attatccact gattcagatg aattggcaat tcttgaacaa
    12001 gctttgtctg acagtggatt gctactggaa cttcaggaca tattgagaaa agaaaaatgg
    12061 ggtcatcctc aatctgagca tacaaaagga agaaccatta gcgccgaaga agcaaatgaa
    12121 cgaaacatca ctgaaaatgc tgaagaaatt ctgcgcttag atgaaaagaa atcgttgtct
    12181 gctgaagaac caaatgaggg agaagagaaa caagaagaaa caatagaaaa aaacgagatt
    12241 cctcctcaaa tgcaaaaaga acgcagtagc gatatcgaag gaaaaaatca aaaagaacaa
    12301 caaacaggag atgattctca agaaatgtct gcttctgaca tggaagcaca tgataaggaa
    12361 atcaagaagc aactgaataa agaagcgcga caaatcatga aggaaacgat tcatgaaaaa
    12421 gaaggtctca tcgttcaccg accagctttc caaggaaaaa cgccggaagc acgtgagcta
    12481 cacatgcaag taatgccaat agtagaatca cttagccggc aaattttaga gttactggat
    12541 aatgaacaaa cagagacgta ccaaaaagga aaatacgaag gtcagcggtt caatgcaagc
    12601 aaagtagcat atggtgattt gagaaatttt gacaaaaaga acccgccaca tgagcaacct
    12661 tctttagcgg tagctgtacg gatcgatgaa tctgggtcaa tgatacggga tgatcggatc
    12721 gaagcggcaa aaaaagcagc gattgccatt gccgaatttt ctaagaaagt cgatatccca
    12781 ttgttgattt acggagatac agcagaccgt tcgtcaagag aaaagacttc tttgttttct
    12841 tataaagaat ttgaagacgg atttcaatgg ttaaatgaaa aattagtcac tatgaaacca
    12901 aggcaaaaca atcgtgatgg tgctgcactt cgtttagcag cagaaaaatt aaacagacaa
    12961 tccgcaacaa ccaaactgtt gcttaatatt agtgacggtc agccaaaagc gttgccggat
    13021 tatacaggca aaaaagcaaa agaagatatc cagtctgttt tgaaagaata tgaacgtcaa
    13081 ggaatcctat ttgtctccgc agctattggc caagacaaag aagaaatcaa gtcgatctac
    13141 ggtgaaagtc gttttgtaga tattactgac ttgaatgaat ttcccaagca aatgattcaa
    13201 ctgattgccc gctatctatg ataaaataaa gctcaacgaa cgcacttagc agattcgttg
    13261 agcttttcgt ttctagttac cggtaacaag gatacttcta aaatagaatc ggttataatc
    13321 aagagggacc gttaaaggag tgaaacgata tgatacaaga acaaaaatgg tggaaagaag
    13381 cagtaggcta tcaaatctat cctgctagtt tcaaagatag caatggcgat ggtcaaggag
    13441 acatcaatgg gatccgtgaa aaacttaatt atttgaaaga tcttggtatc ggctttatct
    13501 ggatcaatcc gatctatcaa tctccatttg tcgataatgg ttatgacgta agtgactatc
    13561 aagatataga agagagattc ggaacgatgg aagattttga tttattgcta aaagaagcac
    13621 atgaattagg gatcaaagtg attatggatc ttgtcatcaa ccatagttcg gatcagcatc
    13681 aatggtttga agaatcgaaa aaatctaaag aaagcccgta tcgcgattat tacatttggg
    13741 tcgacggggt agatggcaaa gaaccgaata attggacatc gattttcggc ggttctgctt
    13801 gggagtattc tcatgaaact ggacagtatt atctgcatgt ttttgcaaaa gaacaaccag
    13861 acttaaattg ggaaagcgag aaattgaaag aagaactatt caatatgatc cgatggtggt
    13921 tggataaagg gatagatgga tttcgtttag atgcgatttc tcatgtaaaa aaagatgaat
    13981 attcagtaaa agccacagag aaccctttct caccctttca aaatgtctca ggaatcgaag
    14041 aacatttgac cgatttgaaa catgtttttg aagagtacga tatcatgact gtcggagaag
    14101 caagtggtgt cactgcagaa gaaggaccac aatgggtagg gaaagacggt tatttcgata
    14161 tgatattcga atttgatcat atccatatct ggcagcaaga aaaagaaggg caattagatg
    14221 tccttaaatt gaaacttgca ttaagcgctt ggcaaacttc attggatggt atcggatgga
    14281 acgctttata tatggaaaac catgatgttc ctcgtgccgt ttcagtgttt ggagatactc
    14341 gtcccgattt ttgggctatg tctgcaaaag caatcgctat gatgtatttc tttttgcaag
    14401 gtacgccatt tatttatcaa ggacaggaaa tcggaatgac gaatatgccc tttgaatcga
    14461 tcgatcaagt tgatgcagta gattcgaaaa gactttataa aaggctgctt gcggaaggta
    14521 agacaagaga agaagcattg gatatcattc gtgaaacaac gagagacaac agcaggacac
    14581 ccatgcaatg gacttcggaa caatatgctg gtttttctac acatgaacct tggctgatca
    14641 ctaatccaaa taccaaaacg atcaatgtag aacaacaaga atatgaacca gagtcggtcc
    14701 tgcaattcta taagaacatg atccgcatta gacaaaccaa taaaggtctg atatacggtt
    14761 cttataaaga atatcttcat gaacatccac aactttatgt ctatgaaaga tatttagaag
    14821 atgaacaata tcttattatg gtaaacttaa cagaatcact tgctgactat gaacttccaa
    14881 aagaagcaga tcagtcctgg acattactct tgtcaaattc ctctagcgga gaatttgaag
    14941 ctaaaggcat actagcacct tatgaagctc ggttatataa aacaaacaag taaaacttcc
    15001 tcgttaaagt tcattagttg gactttgcga ggaagttttt cagattgctc tgtcaattac
    15061 tcatttcaat aattcgctct aggaccaccg atatatttag gacgagagcg aagggctgtc
    15121 acgtgagctt gtccaagggt tttcaaacga ggtctgacag gtacttggac atgtttgata
    15181 tgcataccga ttgatgtgtc accgatatcg ataccggctt gtccaactac gtgttccact
    15241 tcgacaggat cattgaactg gtcaaaagca gcaacagaac aagcacctcc agcatgtagt
    15301 gcaggaacaa cagagacaat ttcgaaattt tttgcttctg ccactgttcg ttctactact
    15361 aatgctcggt tcaaatgttc acaaccttgg acagctagcg caatttcttt aggatccaac
    15421 aactctttta acgtacggat gatccattga ccaacttccg cactggaatt ttttccaata
    15481 tgtcctccaa cgacttcgct tgtgctgcat cctaaaacaa aaagatcacc ttttttcaag
    15541 tgtgcctcag ccaatatgtc attaactatt tcagtcaatt ggtcttttaa ttctttttct
    15601 gacaacttca ttttctaaaa ccttcttttt caattaatat tgcttccgtg cttgaatacg
    15661 ttgaagactt gcagttatag gaaaggcaag tcccattcca atcagatttt ggaagatgtt
    15721 tcctggtata gaagccactc cagccggcca atcatataaa atccaaccgg cgataccata
    15781 gccgatgatc ataactaagc ttcctaataa aagccctaat ccccacatac gagtagaaga
    15841 tttgctgaaa gaaccagcaa catatccttg taacccgtgg atcactaatg aaaaaactgc
    15901 ccactgcgga tatcctgaaa tcaaatcgat caatagacca ctggaagcac caacaactaa
    15961 tccacccgtt ggaccataaa gaaaagcagc ggtatagatc ccggcctcgc ataatgtcac
    16021 aaatccattc gtagccggta cagggatcaa aattgttaat gaaagggcaa ctgtcaacgc
    16081 aatcagcata gcatagatcg ttaattgctt agttttcatt tctcattcct cctttttgaa
    16141 taccgccaga ccagacactt ccggtatgat cgttcatcag cacgccatta gaaatacaat
    16201 gggcaacaaa ttttttactt tctgctactg ctttggtaaa atctgcccct aacacaagat
    16261 tcgctgttat tgcagaagaa aaggcacaac cggccccgtt tactgttgta gtgtcgattt
    16321 ttttatgaga aaatacctca taatgatcaa ttgaatagag aagatccaca gcttcatctc
    16381 cagccatcct tgtgccgcct ttgatcacaa tgttttttgt tcctgaagca gtgagttctt
    16441 tagcgagatg gatcatttct gttaacgaag agggaagagc ttgaccagaa agtaaagcag
    16501 cttctgccaa attaggcgta atcatcgtaa caagtggaaa aagttcttcg atgagctgcg
    16561 aaatatacaa ttgattgatc acagcttcag tttctttgaa tgccaaaaca gggtctaaaa
    16621 tgattgggat attttgtttt gtttttatga agtctcgaac aaccatgatt gcttcacttg
    16681 aattcaataa cccaattttg ataccatcta atgaagtcat tttatcaatc gaaactaact
    16741 gtcgtttaag caattccaaa gatatagatt ccagcataaa tcgctcatta atatctagtg
    16801 cccctataga agtcaaggcg cttagtccga atagaccaaa attctcaaaa gtttttaaat
    16861 ctgtttggat tcctccacca gcaaatggat cagaaccgcc aattgtcaag attcttttca
    16921 taacattttc ctccatgaat aagagtataa cgaaattttc aaaaaagaaa aacagccaat
    16981 tggcatattt ttatctcatc caatttaaaa aaacaaaaag aaaagaaaga ccaaaatgga
    17041 tctttctttc cttaaatagt taggactttt gtgattttaa ttctttctcg atttgaagcc
    17101 gttgcacttt cattgtagct gttcgcggga ttgcatcaaa atcacggatg atagggacgt
    17161 tcaagcgagg aagttcatgg acttgctccc accatcgatt ccaatccatt tctttatcag
    17221 gagctaaagc aataatcggt tgtggagaat gatttttatc ccttacaatc actacttctg
    17281 ccaaaaaatc taacgaatct aataaaaagt cttcaatagc taatgtacta ttgatcgttt
    17341 cgatcaaatc cacttgccga tctttcaaaa ataggtggcc atgcttatcc ataaaaccgt
    17401 aatctccgct atcccaccaa tcgccataaa cattttcctg gaaccgtgca tcttccttgt
    17461 aataagtcaa agcccgtcct ttagacagta attgtatatg accatctgtg ttttcaggta
    17521 ggacattccc aactgaatct gtaatccgag cgcttgtcat gtcttccagt ccaacgccca
    17581 tatctcttgc atcacttgtt ttcaaactct ctagtgtatg agccttaaga atcattggtc
    17641 cgcattcact ttggccatat acttgaagaa ataccgcatc ctgtgccatc gacgttcgca
    17701 aaaatgtctt cattgtctgg ttgtttatag catcaaaagt ggagtgatag tatcggatac
    17761 ccgaaaaagc ttctggatgc tccttagcag taaaacgcca ctgaacaaag ttattcggat
    17821 gggtctctag tgcaattggc cggtgagctt ccaacatatg aacaactttt gaactttgtg
    17881 cgtttgctaa aggcatcata ggaaatccca tggacatcaa agaagagata ccaatattga
    17941 atctggaatg cactggagag atgtgaaaag cgattaattt cttttccgaa atttttgtga
    18001 aaactgtttt ttgccatttc gtccgccatc ccatagaatg agcagaatga caaataagtt
    18061 tagggatacc agttgtacca gaagtatggg tcatataaga aatttcattt ttgtctaaaa
    18121 atgattgaga aacagacaaa gcaggttgtt ccattaaata aagaatagga
//
LOCUS       DADQCX010000058        18160 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.058, whole genome shotgun sequence.
ACCESSION   DADQCX010000058 DADQCX010000000
VERSION     DADQCX010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.058"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(179..544)
                     /locus_tag="J8R83_001801"
     CDS             complement(179..544)
                     /locus_tag="J8R83_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574931.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            752..1234
                     /locus_tag="J8R83_001802"
     CDS             752..1234
                     /locus_tag="J8R83_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574932.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1431..2321
                     /gene="pstS"
                     /locus_tag="J8R83_001803"
     CDS             1431..2321
                     /gene="pstS"
                     /locus_tag="J8R83_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAZ9574933.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(2608..3882)
                     /locus_tag="J8R83_001804"
     CDS             complement(2608..3882)
                     /locus_tag="J8R83_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9574934.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            4155..6626
                     /locus_tag="J8R83_001805"
     CDS             4155..6626
                     /locus_tag="J8R83_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9574935.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(6729..8465)
                     /locus_tag="J8R83_001806"
     CDS             complement(6729..8465)
                     /locus_tag="J8R83_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAZ9574936.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(8462..9166)
                     /locus_tag="J8R83_001807"
     CDS             complement(8462..9166)
                     /locus_tag="J8R83_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574937.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            9297..9800
                     /locus_tag="J8R83_001808"
     CDS             9297..9800
                     /locus_tag="J8R83_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAZ9574938.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            9760..10098
                     /locus_tag="J8R83_001809"
     CDS             9760..10098
                     /locus_tag="J8R83_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAZ9574939.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10119..11537
                     /gene="ffh"
                     /locus_tag="J8R83_001810"
     CDS             10119..11537
                     /gene="ffh"
                     /locus_tag="J8R83_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAZ9574940.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            11649..12227
                     /locus_tag="J8R83_001811"
     CDS             11649..12227
                     /locus_tag="J8R83_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAZ9574941.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            12231..12752
                     /locus_tag="J8R83_001812"
     CDS             12231..12752
                     /locus_tag="J8R83_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9574942.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(12831..13385)
                     /locus_tag="J8R83_001813"
     CDS             complement(12831..13385)
                     /locus_tag="J8R83_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAZ9574943.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            13638..13913
                     /gene="rpsP"
                     /locus_tag="J8R83_001814"
     CDS             13638..13913
                     /gene="rpsP"
                     /locus_tag="J8R83_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAZ9574944.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            13925..14176
                     /locus_tag="J8R83_001815"
     CDS             13925..14176
                     /locus_tag="J8R83_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAZ9574945.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            14301..15092
                     /locus_tag="J8R83_001816"
     CDS             14301..15092
                     /locus_tag="J8R83_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574946.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            15262..15783
                     /gene="rimM"
                     /locus_tag="J8R83_001817"
     CDS             15262..15783
                     /gene="rimM"
                     /locus_tag="J8R83_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAZ9574947.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            15773..16534
                     /gene="trmD"
                     /locus_tag="J8R83_001818"
     CDS             15773..16534
                     /gene="trmD"
                     /locus_tag="J8R83_001818"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAZ9574948.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            16670..17017
                     /gene="rplS"
                     /locus_tag="J8R83_001819"
     CDS             16670..17017
                     /gene="rplS"
                     /locus_tag="J8R83_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAZ9574949.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            17275..17568
                     /locus_tag="J8R83_001820"
     CDS             17275..17568
                     /locus_tag="J8R83_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAZ9574950.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         6030 a         3240 c         3698 g         5192 t
ORIGIN      
        1 ttcaatatct attattggaa tcattattgc tgcaattatt acacaactgt ttttagtgtt
       61 tggagagaag aaaagaagta aaaaatagaa aaactagtga tagttttggt gatataagaa
      121 aaacatatat gtataaaaag aagaaagtag cttctctttg tacatatatg gtttgttttt
      181 atggatgccg agctttttta taagataagg ctaccgccca taacgaccca aggatttgtg
      241 gaactaagta aatacctgca agaagcaaga tcagctgggt cggttttaaa ggatgataga
      301 agtaacgcca ttcagtaaaa ttggcgcaaa ataaatagga agtgacagta gatataatat
      361 tggcaatgaa taaagatata atacgcctgt tcctttgaaa ataatatcca gcaaaaagag
      421 ataaaaatat caatgtgatg aacccgctta cggaatgata acgaaaatca agcagtaagg
      481 cgaaatgcac ataaggaaca aaagataaaa gcaacggaag gtttttccag caagttttta
      541 tcatctttca tcaccaccta acaagtgtta ttattttgtt agttttattg taaattgaat
      601 cctgcaataa tcaattactt tttcattatt tctagattaa atgaataaac tctcatgcca
      661 ttatctctaa aaaaaaagtt tttcccccta atttttttag atagaaaatt gtatagtatg
      721 atgagagaaa aagtagtttg ggggaacgtt aatgagaaga aaagcagtaa tcgatcggct
      781 ttatttattt ttttggtttt ttcctatcgt tttgctacct tttacatggg taaatgctgt
      841 tgtacaaggt gcggagatat taggcctgat ccaaggaagc ggatttgtgg tttctaggaa
      901 ttttccagct ttgattgttt tctatttagt gataagtgta ggtctcttat taccaaaatc
      961 tctgatcaat cactacaatt ggcagctgct ttacttttct tgcttattag tatttacatc
     1021 tatgttttct ttgctgcctc gcttgattat cggccctaat ggtttgagcg agagtggatt
     1081 gaaggattta gcttattcct ccatgtattt cttgacgatc aaaccatggt tctatttagt
     1141 aattgcctca tttattcttg caacattttt ttacttctgg acagaaatca ggataaaaag
     1201 tgaacgatct gtatctataa aaaataacta ttgatggtgg atcatcagta aaaaaacata
     1261 tgagctgcgt aaaatgcatg tttctcatat gcttttttta ttattatgta aagaatgcga
     1321 aaaacgttta catgattttt acataactta actatatttt tacagcaacc atacgaggga
     1381 tttacagtcg actgataaac tttagttgta aataagaaag gagcaataaa atgaaaaaag
     1441 tattgtttac tctaggtatg atgggaattc ttttagccgg atgcggctca ggatcaggaa
     1501 atacagatgg ctctgccaca caaaataatt caagtgactc aaatgaacaa gtaaaaatcg
     1561 ttgcggtagg ttcgacagca ttacagccgt tagtcgatgc agcacaagaa agctttgtac
     1621 aagaaaatcc aaattatcaa atctctgtac aaggaggagg aagcggaact ggtttgagcc
     1681 aagtcgaagc tggagcagtt actatcggaa actctgatgt atttgcagaa gaaagagacg
     1741 gagttgatgc ttcaaaatta gtggatcata aagtagcagt ggtcgggatg gcaccaatcg
     1801 tcaataaaga tacagatgtc aaagatatca ccaaacagga attgattgat atctttacag
     1861 gaaaaatcac taactggaag gaagttggcg ggaaagatca aaaaatcaac gtcgtgaacc
     1921 gtgcaaacgg cagcggtacc cgcgcgacat tcgaaaaatg gggactggat ggtgctaccc
     1981 ctgtgcagtc ccaagaacaa gattcatcag gaacagttcg gcagctggta agtcaaacac
     2041 caggagcaat cagctattta gctttctcat atctcgatga ttccacacaa gcactaagta
     2101 tcgacggtgt agaaccaaaa gaagagaatg tagcagataa cagctgggga atctggtcat
     2161 atgaacatat gtacacgaac ggaaaacctt cccctgaagt ccaaaaattc ttagactaca
     2221 tgatgacaga agaaatccaa gaaggacctg tcaaagaatt gggctattta ccaatcacaa
     2281 tgatggaagt agaacgtgat cacgaaggaa atatcaaata actagcagat aaacatgcca
     2341 cggtagtcgt tactattaag gaaaaatcaa ctatgtttcc ccacatatac atttttcctt
     2401 taattgtgaa aaatagttcc tcatattttg ccgttttttg agctaatacc gagggtcagc
     2461 tgattgaaca ccgtttattc gaaaaaaaga gctacgacat agaactgtcg taactttttt
     2521 tggctcttcg tcaaatcgtg ttggtgaaga caaatttgaa taaaacttag tccgatatgc
     2581 ggcgcgttct gtgcgccgca tattttttta gttttcaaag atcagacctt gttgtaaata
     2641 gatccgtgcc cgaaagttat aaaagttgcg ataaccaaac gcaattcgtt taatcagctt
     2701 gatcttgtta ttcagcccct cagtgacgcc gtttgagtgg gacaccttaa aggcatttga
     2761 aatacccgat tggtagcaat ggaagatcgt gaatttcttt ttaaacgact gaggtaacgt
     2821 agatgaaatt gttttaaggg tttcttgaaa gccttccgta cctcgtttaa cgaaataata
     2881 gcgtaataat tgacaaaaat gatacgcagt tcgcaattct tcgttgtagc ttaacagctc
     2941 atcaacgatt tctgtttgac taattggtcg tttaaacagt cgatgataat gccgtttgag
     3001 tggctcccat gtcgtggaat ctttgagtaa gagtttccaa tatcgcttga gccgacggta
     3061 cttcttctga ttttcagagt gtgaggttcg aaaacgattc atgatctgga cacgtaattg
     3121 attgaagctg cgattgatgt gttggacaat atgaaagcgg tcagttacga tctccgcatt
     3181 tggaaagact gttttaagca actgacaata gctggcattc atgtccatca ctaggtactt
     3241 gacctttaaa cgggcctttc taggaaagcg caggaagtat tgagttagtt tgtaaagtct
     3301 gcgatcttca aggatcgtaa atagctgatt ggttgtccca tcaacacaaa taaaactcat
     3361 ggaaccagaa acagaattca ttgatttgaa ctcatccata cacaacaccg tcggaaggaa
     3421 gttcatacgt ggctggtaat gcttcgttgc ttcacgcaag atccgtgtca ccgtcccatc
     3481 cgagacgaag tacttcttag cgattagttt acgtgattga ttttcgtaca gttccatgag
     3541 aatcgcctgc ttcagttcct ttgttagttg atgatgttca tcaactaagt ccgttttcgc
     3601 agaaaaggtc cttccacaat catggcagag aaaacgggta cgttttaatt ctaaaatagt
     3661 taacttttct ttgactttca acatctgagt gcgtgtcgta taggaaccgt tgcggataat
     3721 acgaaccgat cgacagtgtt cacaatagga agaagagtca tccaattttc ctttaataaa
     3781 ctgcgcttga acgcctttat attctttttc aatcagccat tcttcatcaa aaaataaatg
     3841 tttatctgtt aatccgagta attttctagt atgattatcc attgagagac tcctttggta
     3901 ggatgacgtt ttggtcgact aaattttacc aaaagtgagt ctctttttga gttgaaacga
     3961 agaaaaagtg ttagtagaaa atcgccttcg attttccacc aacacaaaat attatagaac
     4021 cctttttttt tgctatatga caggaatgaa aggtgtttgc aagcttaatg tgaggaacac
     4081 tttccatatc tgttctatac tggataggag aagtttggaa atatccagaa aacgaaatca
     4141 atcgaggtag ccacatgaag aataaatgga taaatcgaag taaaaaaaag aaagtaacac
     4201 aaagatcatc agataaagtc atccgtcttt ttccatcgta taaagaagga ttaacggcag
     4261 atcaagtcaa ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat cccacattca
     4321 aaacaaatca gcaaatcgta ttggaaaaca tatttacgta tttcaatttg atctttctta
     4381 tcttagccat tttgctttgt ttagtagaat cctataagaa cttgactttt ttaccagtta
     4441 tcatagccaa tacaggaatc gccatttttc aggaaattcg atccaaaaag atcttggacg
     4501 aactaaatgt tttaaataca gcaaaagtca atgtcatacg agacgggata gaacaaacaa
     4561 tagatataga agaccttgta atagatgaca ttgttatttt agagactgga tatcaaattc
     4621 cagcagatgc agaggtcgtg gaagggaaac tgcaagttaa tgaggcttta ttgacaggcg
     4681 aagcagatga aataaccaaa gaaataggtg atccattaat gtccggcagt ttcattgttt
     4741 ccggaaaagc ttacgcccga ttagacaaag ttggagcaga ttcgtatatt tcccagctga
     4801 cagtcaaagc caagacaatg ggagaaggag aacagtcgga gatgattgct tctcttaatc
     4861 aattgatcaa atggattggg atcatcatta ttcctatcgg tatcctgctt ttttctcaaa
     4921 gttacttttt taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa gcagcattga
     4981 tcggtatgat acctgaagga ctgtacttgc tgacgacgat tgcattagca ttaagtgcga
     5041 ctaaactagc aaagcaaaga gttcttttac acaatatgaa aagcattgag acattggcaa
     5101 gggtaaatgt cctttgtgta gataaaacag gaacgatcac agaaaataaa atgtctgttc
     5161 aaaaaatgat cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa ttggaagcat
     5221 gcattgctga ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa gctgttaaag
     5281 catattttac aaaaaccact gatcaatcct atcaccatgt tattcctttt tcttctgtcc
     5341 aaaaattcag cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg cccgaaatgg
     5401 ttttgcgcga tcaattgccg gaatatgcgg aagagtttgt ttctttcgct gaaaaaggct
     5461 atcgcgtgtt ggtctttggt gtgtacgatg ggattcttga agaaccagta ttgacagaag
     5521 cagtcacacc attaggctat attctgattg ctaatcctat cagaaaagaa gcaagagcca
     5581 catttgatta cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga gataatccgc
     5641 tcaccgtatc caatgtagct gtccaagcag ggatttcaca tgctgatcag tacgttgatg
     5701 catctaaatt atcagaagaa gaatatgaag cagctgtcga aaaatataca gtttttggac
     5761 gcgtcaagcc agaacaaaag aaaatcttcg ttcaattgat aaagcgtaac aatacagtag
     5821 ctatgacagg tgatggcgtg aatgatattc tagccatgaa agaagcagac tgcagtatag
     5881 cgatggcttc cggaaatgaa gccgccatgc aggcctcaca agtggtctta cttgattctg
     5941 acttttcacg catgccagaa gttgttgcag aaggacggcg cgttgtgaac aatattgagc
     6001 gatcagccag cttgttttta gtgaagaata ttttctcctt tttgctctca ctgttttcag
     6061 tgatctttgc tctgacctat cctttagaac catcacaaat cacattgatt agtttgttta
     6121 ctatcggact tccatctttc ttgcttgctc tagaagaaaa caaaaagcga atcagaggga
     6181 aattcatcat gaatgtgatg gaaaaagctg tgccaggtgg actaacagat atgatcgtag
     6241 tcggtgcgtt ggtgatctgc ggggtgactt tgaatctaaa taaaacagat gtttctacag
     6301 catctaccat gcttttgatt gcagtagggt tcctcgttct ctataaaatc tgttcaccgc
     6361 tgaataaatt cagaagtcag atcattcttt tctgtgctag cggtaacttt ttttcggtca
     6421 tctttttgca taagctgttt tcaatcaccg gtatctcagc tgtatcactt ttgctgttga
     6481 gcattctatt tttctcggca gattcgattt ttaggcattt gaccacattg gtagaatatt
     6541 tgtttgaacg taaaaatgaa aaagagcaaa agccgtttag tcgcgtagct aaaaaatttc
     6601 tatcgatatt taaacgagaa aattgacgaa aagtatctca aaaaagagta aaaaagaaca
     6661 accactcgtg tatctttcga agcaggatga gtcatccaac tttaaaacgc acgagcagtt
     6721 gctctttttt acattttcgg aatggtaacg gtgaaagtcg aacctgttcc aagatgactg
     6781 tctacagtaa tcgtaccatt aaggagttgc acgtagtctt ttacaatcgc taaccctaat
     6841 ccggtcccgc ctgaatgtcg gcttcgcgcc ttgtctacgc ggtaaaaacg ctcaaagatc
     6901 cgttcctgat cctcaatgtc gatacctata ccaaagtctt ggacagaaaa cgatagatca
     6961 tctgttgcct gatagcggat aataatctcg ctgtcgcttt ttgaatattg gacagcattt
     7021 tcaatcagat ttttgataat tggataaagg atatctgttt tagtagtaaa tggttcgttc
     7081 tttccaatca atcgaatcgt caaccgtttc ttttcgatga ttggctgata attttgaacg
     7141 atttgctgga aataaggttc tgtataaatt gtctggatct cgtaagaatt ctcgccatct
     7201 tttgacagct ggatgatttc ccgaatcagt ttatctaacc ggatcgcatc tttttgcatg
     7261 atctcaagaa aagaagtcag agtttgcggg tcatcttttg caccatccag taaagtctcg
     7321 gtaaaaccaa tcagtgaagt cacaggagtt tttaattcgt gagagacgtt gccaacgaaa
     7381 tccttttgta gcttttctaa acgtcgcact ttcgttaagt catacgccac ccctagaatc
     7441 tgtccggtac cttctgaatt agtaaagtag cgcaaactca agtctaatgt ctgccgacct
     7501 tctgtaaggg tgatctcctg atggatcagc ggatgctcag gagtcacttg atgaatcagc
     7561 tgaatgagtt ttggctcttg aatgacttct gtgtaccgct gttcaggttg atagcttacc
     7621 acgtttaaat gtagctgcat ctttggatta agcagtagta aacgagaatc agcatcatca
     7681 atcaggaata cgccaatcat cagttcgttc agtaacgtat ataattgctc ttctgtggta
     7741 gtacacgccc gatacatctt actcatttgt tcgctcaacg cattaatcgt ctgatacaat
     7801 tcttcccatt gatcgggtgt ttgcatgatt acttccgcct gattaggatt ttgcaccatt
     7861 ttttttagta cgggcagcac ggttttcaat ggctggtttt tttgatagat cagataatag
     7921 atcattcctg caagaacaag gaagaaagac agaaagaaga aaaagaccca acggcgaaaa
     7981 ctctcagttc tcggtaaaaa aacgcttgtc ggttctgcga tacgtaaaat ggcttctaac
     8041 tggccacttt ttttgactgg taatgcgaca tataaaagat cctcattcaa agtagtactt
     8101 ttgcgcaaag cgctacctag gttcccacca ttcaatacgg ctttgatttc gggacgggag
     8161 tttcgctgtt cattcaatgt ttcattgttt gtgtcaaata agatctttcc agtagcatcc
     8221 attaaagtaa tccgttcgtt cgactgatgg acgaattctt ccaaagcagt tttgttttgc
     8281 gctgcttgga ggttttcgac atctaattgc cggatcagca gttgtgcttt ttttgtcagg
     8341 tagctttctt gctgttccac gatctgctgt tgaaaataat gggaaatcaa ttgccagcca
     8401 ccaaaaaaca aactaactaa aagaataaga aagaagagac gttcataaat ttttttccat
     8461 ttcatcgttt gggttcctga aacttatagc caaatcctct aatagtcacc aagtactttg
     8521 ggtgttttgg atctcgctcg attttttctc gcaaatgact aacgtgtaca tctacgattc
     8581 ggctttgtcc tgcgaagtca aaattccaaa tgcggtctag caatgtgtct cggtcgatca
     8641 cacggtcttt tcgtttcatg aaataaacaa gtaattcaaa ttctttcggt gttagttcaa
     8701 tcagatggtc gtctacggtc acttgataat tggtcaaatc agcagtgatt tgtccaatcg
     8761 atagatattc aggctcagct tcatcttttg attgcttacg aggttcaatt cgtctgaata
     8821 ttgctttcat acgggctaat acttcgcgag gactaaatgg tttggtcaaa tagtcgtcag
     8881 cacctatttc taggccaatg atccgatcca cttggtcatc tttagccgtc agcatcaaaa
     8941 tcggtgtttc atttttttct tgacgcagcc gctgagtgat ctccatgcca tccatcgttg
     9001 gaagcatcac atctaaaatg atgaaatcaa atgattgttc taatgctaat tctaatcctt
     9061 cgcctccatc tgtggcactg gttaccttgt agccttcttt ttccaaattg aacgtcaaga
     9121 gcgttacaat agaaggttca tcatcaacaa ctagtatttt tttcattcaa atctccttta
     9181 aataggtttc attctgttta tattttagca tagaatcagt acaaagggct attttacaaa
     9241 agaaataaat ggtataatag gaaggcactt tgctgaatag aaaggaagag cagtcaatga
     9301 ttggaatcag tgcatgttta ggcggtctgg cctgtcgcta tgatggacag aaaaaagaag
     9361 taccagaatt gatggaacta gttgaaactg gagaagctgt catggtctgt ccagaagtga
     9421 tcggcggatt accaattcct agagatcccg ctgaaatcat tggtggaaat ggattcgatg
     9481 tgtggaaaga tcaagcaaaa gtatggacga caagcggcga agatgtaacg gaagcgtaca
     9541 aaaatggcgc gatcaaagcc tatcaaaaat tgcaggaaaa acacattgat ctagtcatca
     9601 tgaaggaaaa aagcccttca tgcggaaccc attcgattta tgacggaagt ttttccggaa
     9661 taaaaaaaaa tggtgccgga gtggctactg cttattttat tcagcaaaaa atgactgtgc
     9721 tctctgatga agaatggctg aaaactagag gtgagcagaa tggaaatcga aaagaccaat
     9781 cgaatgaacg cgctctttga attttattcg accttattga cagaaaaaca aatgaactac
     9841 atggaattat attatgcaga tgatttttca ttaggtgaga tcgcggaaga atacgaagta
     9901 agccgacaag cagtatatga caatatcaag cggacaagca agatcttgga ggattatgaa
     9961 aaaaaactcc atcttttttc taattatatt gttcgagaac aggtattgga aaatatgact
    10021 gcatatatta cagataagta cccggaagat aaaaaactac ttgaatatgt acagcaaatt
    10081 caagcaatcg aagaataaat aaaaggaatg aagaaaatat ggcatttgaa agcttaactg
    10141 aacgtctcca gcaggcgatg ggaaaaataa gaaaaaaagg aaaagtatca gaagctgacg
    10201 taaaagaaat gatgcgggaa atccgccttg ccttactaga agccgatgtt aacttgcaag
    10261 tagtcaaaga ttttactaag cgcgtacgcg aacgtgcggt aggggcagaa gtgctggaaa
    10321 gtttatcacc tgcacaacaa atcgtaaaaa tcgttgatga agaattgacg atcacacttg
    10381 gttctgaaac agcagagtta aataaatcac caaaaatacc aactgttatc atgatggctg
    10441 gtcttcaagg ggcaggtaaa acgaccttta ctggtaaatt agccaattat ttaaagaaaa
    10501 atgaaaatgc tcgtccgctc ctaatcgcag gggacgtata tcgaccagct gcgatcgacc
    10561 aattgaaagt attaggtcaa cagctagacg ttcctgtatt tgatatggga actgaagtca
    10621 gcccggtaga gatcgtccgt caagggatgg agttagcaaa agaaaagaaa aacgactatg
    10681 tattgatcga tacggcagga cgtctgcata tcgatgaaac attgatggat gagttgaaac
    10741 aaatcaaaga attgacgcaa ccaaatgaga ttttgcttgt tgtcgatgcc atgactggtc
    10801 aagatgccgt caacgtagct gatagcttca accagcaatt aggtattaca ggggtcgtca
    10861 tcactaaact tgatggggat actcgaggcg gggcagcact atcgatccgc tcagtgacag
    10921 gcgcaccaat caaattcatc ggttctggtg aaaaattgac tgacttagaa gtattccacc
    10981 cagatcgtat ggctagccgt atccttggta tgggggatat gctgacattg attgaaaaag
    11041 cgcagcaaga ctacgacgag aaaaaagcgg aagaacttgc acagaaaatg cgggaaaatt
    11101 cattcgattt caatgacttt attgaacagc ttgatcaagt gatgggtatg ggcccactgg
    11161 aagatctaat caaaatgatc ccaggaatga atcaagtccc tggaatcgaa aacgtcaagg
    11221 tagatccaaa agatgttgaa cgcaaaaaag cgatggttta ttctatgacg ccagcagaaa
    11281 gagcaaatcc tgatctgttg aacccaagcc gtcgtcgccg aattgctgcc ggttctggaa
    11341 acagtgttgt tgaagtgaat cgaatgatca aacaattcaa ggaatcaaga aaaatgatgc
    11401 agcaaatgtc caaaggggat atgaacatcc caggtatgga ccaaatgttt ggttcaggcg
    11461 tcaaaggaaa actaggcaaa atggcgatga atcgaatgat caagaaaaat aagaagaaaa
    11521 agaaaaaacg gaaataagat gaaaaaaaca gcttcggtac agactgaaaa tgtctactgc
    11581 cggagctttt ctatcagcaa tttttattct ttactaatac aattactcta aacgaagagg
    11641 tggcacagat gagatgtccg tggagtgaac aaacagaaag tatgcggcaa tatcatgata
    11701 ctgtctgggg tgttcctgaa tatgatgacc aaaagctgtt ccgaaaattg atgcttgata
    11761 ttaatcaagc cggattgagc tggcagacga ttttaaataa aagtgaagca ttcgatgaag
    11821 catatgatcg attcgatatc aaaaaagtcg caaattatgg agaaacaaaa atcagtgaac
    11881 taatggaaaa caaaggaatt attcgtaacc gaagaaaaat cgaagcagcc gtccaaaacg
    11941 ccaaagcagt cttgaaaatt caagaagaaa tcggcagttt ttcagagtat ctttggtcgt
    12001 tttctaatgg aaaaatcgtt gattcttctt atcattcaca agaagaagtc ccaacaacaa
    12061 gtcctctttc agatgaatta gcaaaagatc taaagaaaag aggatttaaa tttatcggaa
    12121 gcacaacaat ctatgctttt ttagaagctg tcgggatcat caatgatcac cttgacagtt
    12181 gtttccgcaa agaagaggtc gtacgtatcg gcagaaaggg cgaataaagc atgcgaaaaa
    12241 tcatatttta tggtgctata agtttagatg gctatttggc aacgaaaacg gatgatcttc
    12301 aatggctttt tgacactcca acaggtaagc aaactactta tgaagctttt tatgaaacaa
    12361 tcgatacgac catcatgggc agaaaaactt atcaggaagc aaaaaaatat ttggagaccg
    12421 aagcaattta tccagagaaa aagaatttcg ttttttccac ccacgcacaa ttacaattgc
    12481 cagatgctga ggtcgtaaac gaagatcctg ttgcttttct aaaaaatcta caaatgacag
    12541 aaggaaaaga tatctgggtt gtgggtggcg gtcgattgat caaaccgcta ttggaacatc
    12601 aaatgattga tgaatggtat atccagatta cccctgtatt attaggggac gggattcctt
    12661 tattccaaaa aggaacatat gaagcgcgtt ttgaaatgct agacacgaca cgattcggtg
    12721 aatttatcga attgcattat gtacgaaagt agaagtaaat aaaataaaaa aggcaactat
    12781 atgcagaaat gtcctgtaca tagttgcctt ttttattacc gttatgcttt ttactctgtt
    12841 aatttgttag aaaaatctag atacgcatct aaaatcgttt ggaagaaact taatgttcct
    12901 tcaacgatat taccattttc atcaattaga ttcgcaacgt ttccgatata tgcttccggt
    12961 tgctgcaagg ttggcacatt caaaaagaca agtgattggc gtagatggtg gtttgcgcca
    13021 aagccgccga tcccacctgg tgatgcagta acgactaaac ctggtttatg atcccaaaca
    13081 ctgtgtccat aaggtcttga gcctacatct aaagcatttt tcaatactgc tggcacagaa
    13141 cggttgtatt caggagtaac gaaaacgaca ccgtctagtc ccctcacttc ctcacgaaaa
    13201 cgagtccatt cagcaggagc ctgttctgga gtttcgagat cctcattgta aaatggcaga
    13261 tcatcgattt ttacaaatac actttcgtac ccttcaggaa gcaatttcgc aaaagcttct
    13321 gctacttttt tgttgtaaga atcttttctt aaactaccaa taaaaaatcc aatttttttt
    13381 gtcatacgat ttttcctcct tcaaactatc tataataatc ttacaaaaga taagtaactg
    13441 gagcaaataa aaacacttac tgacaaaagc tacatagaag atagattact tatttttaac
    13501 aaaaaagaag tctaaaatct tctattttct aaaaaaaatc gaatttaatc aagctgtaaa
    13561 gaaaaaaagc tttacagggt aaaaaaaaac tgttacacta catcttgtga ataaaacaat
    13621 ggaggtggaa ataaataatg gcagttaaaa tccgtttaaa acgtatgggt tctaaaaaga
    13681 gtccgtttta ccgtatcgtc gtagctgatt cacgttctcc tcgtgatgga cgtttcatcg
    13741 aaactgtagg tacttacaat cctttgaaag accctgcaga agtagtttta aaagaagact
    13801 tagttcttga ctggttatca aaaggtgcac aaccttctga cactgtacgt aacatccttt
    13861 caaaagaagg cgttatgcaa aaacaccacg aagctaaatt ctcaaagaaa taaggtgacc
    13921 ggatatgaaa gatttaagcg acttagtctt aacaatcgtt cgtccgctag tcacttatcc
    13981 tgatcaagtc aagttagacg tcgtagagtc gaaagacttt tacgagtaca atctaacagt
    14041 ggctcctgaa gatattggcc gtatcattgg aaaacaaggg cgtgttgcta aagcaatccg
    14101 cacaatcgtt tacggtgttc ggatcaatgc accgaaaaaa gtgcgtttga atatcatcga
    14161 tgataaggaa aagtaaataa acgtgctgta ctcgaatttt cgagtgcagc ttttttgttt
    14221 tttttattaa ttgaagaaat gattatttgg caaaacaagc aagaaagcgt atccttatag
    14281 gaggagggag tgaacagcca atgagaaaga aaatgttatt tattccattt gctctattgt
    14341 taagcgcttg tagttcggtt actcaagaat cagacaatac acatctatca agcagtatat
    14401 ctgaaactgt taccagtcca gaaaaaagta gtaccaaaac ggcttccacc actgaacaaa
    14461 caatggctac ctcaaataat gagaaaaaga ctgctttaga ccagttgaaa gaacaacagc
    14521 caaatgttcc catgcctcta gatgtaccag tctcttcagg ctatctcaat atcgcagcga
    14581 cacatacaaa gcaaggttat tctattttat attacagaac agatcgtccc ctcgggttga
    14641 atgctgacga attgaatcaa gaaacgccta ttgcaaccta tctatatcaa tatgggtttg
    14701 cttctagtca agaaacaatc caagttttgc agccatttga gatcgacaca aatggtcagc
    14761 aagtggactt aggttctcga atcacagggt atcagcaagg tgcagcaggt tcaagttttc
    14821 ttgaatggca agaaggaaac tggcgtattc gaatccgtgg gaataatata gaaggccaag
    14881 atcccttact attagctaaa gaaatcgtag cttatttgga agaaaacagt ctaccagcac
    14941 ctgaacaatt tggtaaaatt actgttgata tgggtgatac gacgaatcga gccgtagaag
    15001 taagctggca agaaccgaaa aatgcctata cgatcactca tcaagatcct atgtctgcgt
    15061 tgaagatggc agtttctatg aagaggttgt gaaatcagcg cgctgatctg agcccatcat
    15121 ttaactccaa gtcacaggaa gtaatcaaaa atagcacgcc gcatttttgc ataattttgg
    15181 cttaatacct taaaagaaaa ctagaattgc ctcttcacac atgctaaaat aaaacagaca
    15241 aaaaagaaat ggggatataa gttgactgaa tacttgaatg taggaaaaat cgtaaacaca
    15301 caaggtatca aaggcgaagt ccgtgttatc tcaacaacgg atttcccaga agaacgttac
    15361 aaaaaaggaa cggtgctaac actattccaa gacggaaaag cacctgtgga attaacagtc
    15421 aaaagtcatc gcaaacataa aaattttgac ttattgagtt ttgaaggaca tccttctatc
    15481 aatgatgtgg aaaaatatcg ggatggcata ttaaaagtgt caaaagacaa ctctgtagat
    15541 ctagctgaaa atgaattcta ttaccatgag atcatcggtc tgcatgtatt agaagatgga
    15601 actgagttag gtaaagtaaa agaaatcttg tcaccaggtg ccaatgatgt ttgggtcgtt
    15661 caacgtccga aaaaagctga tatattgctt ccatatatcg cttctgtcgt caaagaagtc
    15721 gatttagaag ctggagtggt ccgtgtagaa attccagaag gactgattga cgatgaagat
    15781 tgatgtattg actttatttc caagaatgtt tgaaggtcct atgggggaat ccatcatcgg
    15841 taaggctgta gataaaggat tattagatat caatatctct aacttccgcg attattcaga
    15901 taacaaacat cagacagtag atgattatcc atacggcggt ggagcaggta tgctgctcaa
    15961 agtccagccc atctatgata acatccaagc cattgaaaaa gctgcaccgg atgtcaaaaa
    16021 aagagtaatt cttcttgacc cagctggtaa acgattcgat cagaaaatgg cagaagaatt
    16081 ttcacaagaa gaacacttag tattcatttg tggtcattat gagggatatg atgaacgtat
    16141 ccgcacatta gtgacagatg aagtttcctt aggagattat gtccttactg ggggagaatt
    16201 aggtgcgatg gtcatgatcg atgcaacagt tcggcttttg ccagatgtgt tagggaatca
    16261 gacttcagct caaacggatt cttattcaac cggtttattg gaacatcccc aatatactcg
    16321 cccggcagaa tataaaggga tgaaagtacc agaagtattg acaaatggaa atcataaatt
    16381 gattgaagaa tggcaattaa aagaatcact aagaaggacc tatcaacgtc ggcctgatct
    16441 tttggaaaca cttgaatgga cacctcaaat gacgaaattt ttagaagaaa tcaagaaaga
    16501 agaacaagaa aaaacagcag atgaagccaa gtgacttttt ctaaaatctt ctttacagta
    16561 ggttgataat atgttagtat tttatggtga gtgcaaaagc acttaactat tacgatattc
    16621 cgctgtgaga aaagctcata agaatatttg gaataaggag aagaaaacca tgaatccatt
    16681 aatcgaagaa ttaacaaaag aacaattacg ttctgacatc ccagcgttcc gccctggtga
    16741 cactgtgcgt gttcacgcaa aagttgttga aggtactcgt gaacgtatcc agttatttga
    16801 aggtgttgtt atcaaacgcc gcggtgctgg aatcagcgaa acttatacag tacgtaaagt
    16861 ttctaacgga gtgggcgttg aacgtacatt cccattgcat acaccacgtg ttgcaaaaat
    16921 cgaagtagtt cgctacggta aagtacgtcg tgcaaaattg tactacctac gtgcattaca
    16981 cggaaaagct gctcgtatca aagaaatccg tcgttaatca ttgttatcag actgagaaag
    17041 aacccttggt attcaagggt tcttttttct tagcatgtaa tttgaacacc ctgatccagt
    17101 tttttcttta attattggta ggggagaata atggattaga ataaatctac ctataagtag
    17161 tagtaaaaaa aagagcacta tgataatatc tttcttaaga gtaaccgctt taataaaaaa
    17221 tccagaatat tctaacataa atggagtatt cttagaatca aaaggagaaa gaagatggtt
    17281 tatacttata cggagcaaga aaagatgaaa gttttagaca cattcatgaa tgatggaaaa
    17341 gtaaaacaag taccaagttc aacaaaaaag aaatacatcc tattgaaaga agtcttgaaa
    17401 cgctttgacc atggagtgac ttatacagaa acagaggtta attcgatact gctgaacgta
    17461 ttttctagtg gcgattatgt cgaacaaaga cgttatctaa tcacatttgg ctttttcaaa
    17521 agaagttcag acggtcgggc atatcagatg atgggaattg aaaattagaa gttttaattt
    17581 atactcattg aaaaaagttc aagtatgcga tattggttct acaccgcata cttgaacttt
    17641 ttttgtcatc tgtatctata atacaaagcc aagaacgtta ttcaaaatat ggatagctat
    17701 gataaaagct aatgagcgat tcgcagttaa ataagcaatc gtcagtaaaa tcgttccagg
    17761 agcgtacatg aaaaaatcaa ttggatgcgt tacatgaata aagataattc tcttttattt
    17821 gtacgaataa ataccaaaac gtacctccta aaattagatt ttggacagat gccctttaaa
    17881 aagataacaa gatttcgttc ttgaaacaat atatatgctt ttattccaat gaggttgtga
    17941 aaacagtatt ttgtcctgag cgttagaaaa ttgaaaatgg ggaatagcaa ctcgtacttt
    18001 accatttttt aagtgaatac aagatcagct aattgaacac cgtttattcg tgatgaggga
    18061 cacaacactg cagtcgacac atttctcttt tatgttcaaa gataacaaat atttaaaaca
    18121 aagaaaaata gtagataatc ccgtcctaac tcttttattc
//
LOCUS       DADQCX010000059        17739 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.059, whole genome shotgun sequence.
ACCESSION   DADQCX010000059 DADQCX010000000
VERSION     DADQCX010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.059"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(424..1038)
                     /locus_tag="J8R83_001821"
     CDS             complement(424..1038)
                     /locus_tag="J8R83_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9574951.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1644..2021)
                     /locus_tag="J8R83_001822"
     CDS             complement(1644..2021)
                     /locus_tag="J8R83_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574952.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2321..3202)
                     /gene="galU"
                     /locus_tag="J8R83_001823"
     CDS             complement(2321..3202)
                     /gene="galU"
                     /locus_tag="J8R83_001823"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAZ9574953.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3245..4264)
                     /locus_tag="J8R83_001824"
     CDS             complement(3245..4264)
                     /locus_tag="J8R83_001824"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAZ9574954.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4897..5901)
                     /locus_tag="J8R83_001825"
     CDS             complement(4897..5901)
                     /locus_tag="J8R83_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9574955.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5914..6963)
                     /locus_tag="J8R83_001826"
     CDS             complement(5914..6963)
                     /locus_tag="J8R83_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9574956.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(6980..7801)
                     /locus_tag="J8R83_001827"
     CDS             complement(6980..7801)
                     /locus_tag="J8R83_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9574957.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7788..8567)
                     /locus_tag="J8R83_001828"
     CDS             complement(7788..8567)
                     /locus_tag="J8R83_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9574958.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8584..9054)
                     /locus_tag="J8R83_001829"
     CDS             complement(8584..9054)
                     /locus_tag="J8R83_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9574959.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9066..9485)
                     /locus_tag="J8R83_001830"
     CDS             complement(9066..9485)
                     /locus_tag="J8R83_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAZ9574960.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9566..12334)
                     /locus_tag="J8R83_001831"
     CDS             complement(9566..12334)
                     /locus_tag="J8R83_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9574961.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            12534..12758
                     /locus_tag="J8R83_001832"
     CDS             12534..12758
                     /locus_tag="J8R83_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574962.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13537..15252
                     /locus_tag="J8R83_001833"
     CDS             13537..15252
                     /locus_tag="J8R83_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574963.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            15255..17018
                     /locus_tag="J8R83_001834"
     CDS             15255..17018
                     /locus_tag="J8R83_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9574964.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            17183..>17739
                     /locus_tag="J8R83_001835"
     CDS             17183..>17739
                     /locus_tag="J8R83_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9574965.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMM"
BASE COUNT         5251 a         3626 c         3029 g         5833 t
ORIGIN      
        1 tctattagaa aaaggtatcc tgttggacaa ttttgttata tcaggtaaac ttcattgcaa
       61 taatgataac aaatgtacta taattacttt gtaaagagtt ttggggaaga ctctttcatc
      121 aacgtgtatt aagagacaag aaagaatcca tatggattct ttcttgtctc tttttccact
      181 actttttatt tttctgacac tacatattct tataactcat ttctcataac tgtgaaacaa
      241 cttataaaaa taacaaactt taaacaaaac aagcttaaaa tcaaagatga tccatcttaa
      301 aataactaaa acaaaaaaag tagtcgttgt taatcctcat taataatcgt tttctttttt
      361 tcaaacgctc catttttatg tggaacatta tttttttaag gaactttgtc aacatgtgga
      421 taactatttt ccacttgtgt cctggactag ctgttttgct gtaaaataca aaacttgctg
      481 cagcaaaaag atcgttgcaa gagaggctgt tccgcagatc gctggatcta gatttggcaa
      541 agtcaagact gcatcatgta aattggcgtg gttgtccaaa accaaatcag caaattcaaa
      601 taatcgcaaa ccactgctat gttgcgattt gatacttcgt gacaaatcaa atccagtaac
      661 aatgattaat ggatgaccat tttctttgat ccactgagct agttcgatga ttgccgggtt
      721 tcttccttca ttcgaaagaa gaagaaaaat gtcttctgat ttgacagaaa gctgatcaat
      781 aattgcctgt cctgcacctt ctagcgtttc atagacacct ccggctggat tttcaatcaa
      841 tatacttggt acaagatccg gggtttgatc ccaaaattca aatgctacac cacttagtgt
      901 gcggctagca tatatctgca atctaccacc ttgattaatt tgtttcgcga tccaagtgcc
      961 agcttgaagc atcagcggct cttctatcct taatttctct tccaattggt gataatagtc
     1021 aaaataacat aaactcattt atctctcccg cctagctata cttgacatga atagaaacag
     1081 ctgcctaatc taaggaagta cataaaaaaa cagtagttag acagtaacac atgtggtctt
     1141 tgctgtttca aacacaaaaa aggcattgaa cgaatacgcc caataccttg acatagcaaa
     1201 taaaacaacg tgcagaccat ggaaaatatc tacatagggg tagaattttc accctagatt
     1261 aggtacaata aattaggtcg atgcactgca ttgactatgg caaaatgatc ggtcagggtg
     1321 tatgtgtgtg actggtcatt ccctgattct tagcgccaac taagggtcag ggagcctttt
     1381 tttattcagc tgtttctatc tgaatttatt gtaagtaatc tcttatccaa gtgcaagcaa
     1441 gaaaatacaa aaaaacattg gtatgattta tatatatata tataacataa aaaaaggaat
     1501 ggcttatccc gatacaacaa gcattccttt aaaaaagatt cttttatata agtgaaaaaa
     1561 gcttttttcc accaattaaa taaatctctc atctcaatag tttatccatt attttatctt
     1621 tttttgcgta tacctactaa atattaccgt cttcttctcg ttcttctact ttgttcgaga
     1681 gaatctgtac tagaaaaagt agttgtatgt ctaccttttc tgcctatccg agactttctt
     1741 ttcatatatg ggatataaat gattagatac agtacagcaa aaaataaagc aaatacgcaa
     1801 gcttcccaac tacctaacgc caattcaacc atcaaggtag caaccccaac ggatgctgca
     1861 taccagataa aaatcagaaa cgtttctttt tttctgacca tgcgaaacat gataaataga
     1921 ctaataagca atagtggcaa cacaaatatc caattgcttc cttccatcag ccacttgagt
     1981 atatcaagca gcgactgtgc aacagcgact aattttccca tagtgaacac acaccttttt
     2041 ttataattaa aaaattcgcc tttttattct actatgaatc ttctggcttg gctttcattt
     2101 ctcttatgta atcattttct tttatacaac ttaaaaaaaa attaaaccat tagcataata
     2161 ttttctgaat ctattcacga aagtcttttt ctatctttcg ttttccacga ctcaactgat
     2221 ctagagtcaa aaaactaaaa cgacagttgc gcaaatgacg cacaagctgc cgctttaata
     2281 acaaatagcc tttcattctc agcaggccac ttatttccag ttaactttct gttcttagct
     2341 ttttactcaa ctggataata tatgcactta atgaagtccc aatttccgaa tgttgaagtc
     2401 catattcaat atttgtcttc atatatccta acttatcgcc tacgtcgtat ctttttcctt
     2461 taaactctct cgcatagacc gcctctgtct ggttaagagt ctgaagtgca tccgttagct
     2521 gtatctcgtt tcctgctcct ggttcttgag tttctaatat ctcaaatatt ttaggagtca
     2581 gtagataacg tccgataatg gctaaattac ttggtgcttt tcccatttca ggtttttcta
     2641 caaacccttt tactctgcaa cgaccctttt cgctatctgt tttaggatca ataattccgt
     2701 atttagatgt ttcattttct ggtacacgca tgacggcaac agcggaagct tgtgtttctt
     2761 cataatccat catcaattgt tgagtcaatg ggatatcatc tttcatcaaa tcatccccca
     2821 gcatgacgac aaacggttca tttcctataa atgcttttgc ttgaagcacg gcatccccca
     2881 gtcctcttgg atgagattga cggatgaagt gaagattgac ttgagtcgtt tcttcaacta
     2941 aagcgagtaa ttctgttttt tccttttccc gcaaattgtt ttccaattcg atatttgcat
     3001 caaagtgatc ttcaatgggt cttttttctt ttcccgttac gatcaagatg tcttcgattc
     3061 ccgaatccaa tgcttcttcc acaataaact ggatcgttgg tttatccacg attggaagca
     3121 tttcttttgc catggctttt gttgccggca aaaaacgtgt tcctagccca gcggcaggaa
     3181 tgactgcttt tttgaccttc acttgctgtt cctcctaaac gacgattaac tattgatcat
     3241 ctatttaacg aagagaaaat tcattctcca tttttccgtc acgtaacatg atttcttttg
     3301 ctgctttttt gatatcttct ccattataca aaacattata gattgtttga gtaattggca
     3361 tctcaacacc tagctgttga gctagctcta ctgctgcttt tgtcgttgcc acaccctcaa
     3421 cgaccattcc catgttttct agaacttctt ccagcttatg tccctgtcct aacaagttac
     3481 cggcacgcca attgcgagaa tgaacacttg tacaagtaac gatcaagtcc cccacaccac
     3541 tcaaaccgat aaatgtcaga ggattggcac ccatcgcgac accaagacgg ctgatttctg
     3601 ccaatcctcg agtcatgatt gctgcttttg catcatctcc gaatcctaat ccatggatag
     3661 cgccggcacc aattgcaatg atatttttca gtgctgcacc agtttctacg ccaatcacat
     3721 cattatttgt ataaatcctg aaataatcat tcatgaacag tttttgtaca taggctgctg
     3781 ctttttgatc aatacttgca gctgtaattg ttgtgatatc atgtactgcc acttcctcag
     3841 catggctagg accagataat acaacaattg cctgtctttt ttcttctgga atttcttcag
     3901 ccaaaacttc tgagattcgt ttatgcgtat cttgttctag tcctttactt gcatgtataa
     3961 tgattggctt agtattcatt ttaccaataa gttcctgtgc gactgaacga atcgcttttg
     4021 ttggaacaac aaataaaata gcatctgcgt tatccactgc ttctgccaat tctttatatc
     4081 cgataatcga ttctgggatc gtcaaatcag gtaaaaaatg ctgatttgta tgatacttat
     4141 tgatttcatc aatctgttca ggtacatttc cccaaatacg gacatcatgc ccgttttctg
     4201 ccaatgtttg tgctaaagca gtgccccaag atccaggacc aagaactgcg attttttgtt
     4261 tcatggatat tcctccaaat aaataattga taatttccat tatagtatac atttcttaaa
     4321 gttgggacta atttccattg tttttaagtg tttgtttact tcttttatcg tttttacttg
     4381 aaataatcaa tgatatgtta caatagtcta cattttattt ttacactcgt tatgctttgc
     4441 ttgttcctaa gaggaagcag ttttgacaat gttactacca gcattactat taggaggtta
     4501 ggaaacttct cctagtgagt attgatttaa aatacataag agacagattg aacatttcta
     4561 aatctgtcag gtcctgcaac ggacagattg tctctgttga cggttgacat aggaactttt
     4621 gttttagtca acattctgga tacaaaacgc tatgtaaact ggcgcaactc gttgtacttg
     4681 gacttttact acggatccat gcaacaacta aatagtacta ttgcataaca aaaaatggtt
     4741 ggcacccaca tgtcccatta aacagattat aagttgaact gtagataatg caaaaaatgt
     4801 gttttataac gtaattgatg ccaatatttt aaaaaaataa agggagcagt tatcgctgct
     4861 ctctttattt tttatattct ttttatccag tctatcctaa taatcaaact gacgatagta
     4921 gcggcgtatc tctaatggat ggcagttcaa ctgctccaca tgagcatcga tgcgttgtgt
     4981 cactacatgc atcaataaga aagacaaaac acgtccgcga tatttttcac tgataccttc
     5041 tactggatag tcttttgtgt ctatcaatgt ataattgctg caaatttttg gcaaaagttt
     5101 agccacacgt tcagataaca ctctctgttc atcttcgcct aaaaataatg tgactggggt
     5161 tgtttcttct acgatctcta acgtcccgtg aagaaactcg gcagcatgga tagatttcga
     5221 tggaagccag ctttgttctt cccagtaaca catggcatat gaataaacag ctccccattg
     5281 attccctgct ccaataaaat aatgcatact atcacgtcga tgtttttctg caaatgataa
     5341 gccaaatgca tctgcttttt tctctgcttc cactaaccct gttggtaaat aacgttcgag
     5401 ctgttcatag tattctgaat aagcttcgaa ttctccattc aaatacatca atcgatctgc
     5461 tgccataaaa aatttgattt gttctgttcc aggagctgga taagtgacca caaaatcgca
     5521 tagctgagac aacttactgt tcgctttatc gataaatcca atcagtgtcg ctcctacttt
     5581 cttgatttgt tctactgctt tcactacttc ttgagttgta ccggtaacag aggacaaaat
     5641 aacgatagaa tcttttgtta atcttttgtt tccagtagtg taatattctg cagcatgctg
     5701 tacaaagaca ggcaagttgc ttttcccatt catataagtg acagcttgca tcgaggaagc
     5761 atacgttcca ccgattccta gataatagac agcgtcaaat ttttccgcat aaagtttatc
     5821 gatgatttct tctacttgcg gacgtaaagc tagtgcgcct tttattgctt tgatttgttc
     5881 ttcttcattg aatttcagca tgatttccac ctcttataat ttacttttca agactgtatc
     5941 aaagtcttca aaaatctttt tgttcaagtc aataccttta gctactgcgg ttttataagc
     6001 gaatagttga aacggaacga caagcgctaa tacagacaga tattcatcac attctattgc
     6061 taatccaagt gttttctcgt ttcttgcttt ttttgtggta atggtgagag tctctccaac
     6121 gtaccgactc atatatcttt gcaacttttg cgaacgttcc ttatttacac tttccccttc
     6181 aataaagaat agcaaatgcg aagcatctgc ctccaggtat gggccgtgca tataagcttc
     6241 taactcaaat ccttgtgacg gaacgcggat tgtttcagtc aatttcgtct ctgcttcttt
     6301 agctgttccc cagtttggac catatccaat ggtgacgaaa cgctgtgcta aacgaaataa
     6361 actttgatat ccatcaaaaa attcttccgt tttttgaata atcgctggta aatggttgat
     6421 tattttgcgc aactgttgca tgtagtcttg ttctattttt ttgctgattt tatttttact
     6481 tattccaatt cctatcccta agagtagtaa ctgtaaaaca gtcgcagaat agccttttgt
     6541 aacgaagcct actgattcta ccccggcacc taaatcaata atttgtgcag cttctaaagc
     6601 aagtggactt tgcacgtcat ttgtgatagc aacaacaggt aacccttgtt tttgtatcat
     6661 ttttactgct tcaacagtag aagcactttt cccgctttgt gacacagcaa tcacagtatc
     6721 gattgaagga gaaagttttc cataattgaa aaaataaaaa ggttcttgaa tatcgacagt
     6781 aagatcacca taagattcca atgctggctt cgctgctaaa caagcgttat aagatgaacc
     6841 cgttgctaag atcagtaaat tcactgtttt tttcatatgt tctcttgtcg aaaaatcatt
     6901 ctttttcaag atcgtactta gtacttcctt ttcttcatag atataatctt gcatcgtaaa
     6961 cattttctct gctccttttt taaaaaatcc ctatccacga accaaaaatt ccaaagaaag
     7021 ctagtccgat caagatcgtt aatggtttca cttctttctt caatagataa aacactatgc
     7081 caaatgctcc aagacataag atatttggaa cgatatcatc aaaaatactt tgaacagtca
     7141 cagcattttc tcctgaaccg atttttaaag gaatattgat ggtgatcatc gtggcagtca
     7201 ttgctccaac gaccatcagt ccaataatag acgcgcctaa tgtcaaactt tccatcatac
     7261 cgtttgcctg gatctttttc aaaaaacccg ttcctaagcg atatccccaa cctgttgcta
     7321 gatagcgaaa cagaatgtgc ggaatattga aaatcaaaat gaacaagata gggcctaaaa
     7381 tatttccttg catggctaaa gaggtaccca cacctgtggc aatcaatcgc aaagttcccc
     7441 aaaagaaaga atctcctaac cctgcaagag gtcccatcaa agatgttttg atactatcga
     7501 tcgcagtcac atcaaattca ggatcatcct tattttcttc ctccattgca gccgtgattc
     7561 ctaaaatcag tgtaacgata tgtggggtcg tgttaaaaaa ctctagatgc cgtttcaaag
     7621 ctgctgccat ttcttctttc gactgatata actttttcaa aatcggaatc attgcataaa
     7681 cataagccat attcatctga cgttcataat tccaagaaaa ctccatttga aaagaacgcc
     7741 aaaatacgtg atttagctct tttttcgtta ttttgctgtt tttgatctca gaattcttca
     7801 tcttcttcta cctcccctgc agttgtttga agtggtagtt gacggacatt cataatattg
     7861 actaccacaa ctgctaaaat cgcaccaaaa atagctactc cggtcacagg aatctctaag
     7921 taagaagcta tagcaaaacc taagaaaaaa tatggtgcaa cttgtttgtt gatcagcaaa
     7981 cgagcaagca tcgcaaaacc aagagctgga atcaaccctg tagctactga caaccccttt
     8041 tgaacgaagt caggaatcat atttaataga tttccgatcg tattgcttcc caccatataa
     8101 gaaaccatta ccacaacacc aagcatcaag gaaagaccga taccggcaag caagtgcata
     8161 tgctcgactc ctttataatt tccttcttct gcataattgt ctgctttatg gttcataatt
     8221 ggaatcaaaa gccctaagta aatatttttc aatatcaatg tcaacgtagc aatcggcaaa
     8281 cctagtaaaa gcgcggtttc tgtaccggct ccagctgtaa tagcaaaagc cgtccctaaa
     8341 atcccaccgg tcacaacatc aggtggaatc gaagcaccta ctgagaacga tccgataaat
     8401 gctaactcta aagttgcgcc cataatgatc ccagttttta catcacctaa cacgattcct
     8461 gtaaacagcc ccgtcacaat cggacgagaa agcaacgatg tccctagtgc atattctgat
     8521 tgtgcgacaa atgcaacaat tcctaataag actgcttgta caatcattga ggttcttcct
     8581 ttcttacaaa acttctctta catccacttt tttatctgct ggtacttgac ggatttctac
     8641 ttctatttgt ttgtcaatta atcgtttcaa gcgttcctcc tcttctggta aaatatttac
     8701 cgcttttccg atgctgcgag taccaggttt tgccttgatc cctcctaagt tgatggtttt
     8761 gatttctgga tacgcttctg ccagcttata tgcatcctcg atcgattcca ctacgatgaa
     8821 taacttatat ttatctgtca ccccgctttt caacgcggca atcgagtcat caattgattt
     8881 gatcactagt ttgactcctt gtggcttggc taatttgatc gttgtctttc gtatctcatt
     8941 cgtaggtaca tcatcattag caatcaaaat acagtctgcg cctattgttt gtgtccatga
     9001 aaaagctact tgtccgtgta ataaccgatg gtcgactctt gtcaatacaa tcatttttct
     9061 tcctcctaaa attcgtcttc ttctattttc tgattgagcc gctcgttaca aaactggatc
     9121 attttttttg aatcagttag cacctgctgg atcaaaacag ttgtctctac ttcagcgtcc
     9181 aaccgagata ctagctcaat caatagtggc aaattcaatc cggcaacgag atagacatga
     9241 tcccgattga tatattgtaa gaattcgttg ttgacacttc cgccaaaaag atccgtcaga
     9301 acaatgattt ctttatcttt gtacctcata aaaagctgcc ttactgtttc cgctaaatca
     9361 aaattctcat cagtatagca atcgaataca gtaatagaat gatttttccc atagatcagc
     9421 tctaatgaat ctaatatccc tgaagcaaat tttccatggg aagctaagat aatttctcta
     9481 tccacttttt catctcctct tttcacttac acatactaaa aaagcaagtt gcatgccaaa
     9541 attagtggca acaacttgct tatgttcaaa attcttcttc tatcgagaga aactctgtat
     9601 cttcactcaa aatatcatag atataggcaa tctcagaatt ggggatcatg acactataat
     9661 gctcttcaat gacactaaac gcagatttaa tagcagataa cccttctttt tgacactgct
     9721 tccatttctc taatccttga taggtttcga ttggcatttg tcggatcaat cgttcaatga
     9781 gacagctcac atggacatac aacgctaatt ttttgggatt gctgatgctt cgattcaact
     9841 gcacctctaa ttctctcata aaatgatcga tttctcccat caccttctct gtatctagaa
     9901 tagtcacgga atccagtact ttttccaatg aaaaattacg aatgatgcgc tgattgaata
     9961 tttccttctc tgaagcattc atagtagtgt ccaaccattc agctagtaca gacatctttt
    10021 cccccgagat gaggtcttct aatgaaagat agtcgatatt ggtgatatca ggatctgtgg
    10081 tgccaatcat tcctacgact tcgtatatgg aaaataatgg gtcactgttt ttcttatctt
    10141 ttaattgctg atattcatat gggatgattt tcaactgaca agccgtaggt aagctttttt
    10201 ctagcagttc acttaagtgg accgccgtac cgattccagt gaagcaagta gtaatgagtg
    10261 ctttgggttt gttttcctct ggatagagca gtcgccattc tggctggatc tgtcgaacag
    10321 tctcttctgc tatctcttct aatgatacat ttttttgcag gcattcccct actgtgattg
    10381 ctaaaggtgt cgtcacatta ttcaaaatca aaagcggtac ggataactgt tttttaaaaa
    10441 actgatggat ttctttcaga gatcccatgt ctactaatat gatcaatcca tttgaaacat
    10501 cgctgttttc gcaataatca aggatttctg aagcaatctg ctgtggtgtg acatctagtg
    10561 gcatatcaaa tgattcaaat agatcctctt gtaataaacg atttactaca tttgccatac
    10621 tgctagcagt tgcataaccg tgagcagcaa tcatcgcttt tggcagtcgt ttttcttttg
    10681 accatttcgc tttttttaga tagatcgtca gtaaaatccg atccatactt gtgtcttcaa
    10741 tatctaattt gatcttactt aattccagaa ttcgttggac atagtgataa ctagatggat
    10801 aagactgaga aacttgttgt tctaattctt tgattagttg gataatatca tgttcttccg
    10861 gtaaccattt gatagtgctt cgctgataga gatagtaact caaggcatag acactgtttc
    10921 catcgaattt gatttgatag gcagtttcca tttgtcgaaa ggtctctcgg atagattgtg
    10981 tccaataaac cagcagctcg tgtttttctt gtctactggt ctcaaacagc aaaaaatcaa
    11041 ataattgaat cacttcttgc tttaattttc cttcgcaaga atatagcaga cagttatttt
    11101 tcttgaaatc aattaggatt tgctcaaaac ttttaacgat tcgctgctgt tcgggctgtt
    11161 gcttctccat taattgctct aaggtctggt cttgcgtaat atagattcct tgctgtgctg
    11221 tatttttagt aataggctgc gcaagtagtt ctttttgcaa atgatggatc gtgacatgga
    11281 tttcaggctg ttcacgctgt tcagcatatg cttttgctgc tgaaactttg acgatatttt
    11341 tcagctctcc tatgtttccg gataatttct gacttgttaa aagtgacaaa gctggtccac
    11401 tgactgacaa agggctcccc atttttcttt gttcttcgag aaaaaaagag taaatcagtt
    11461 ctagccgttc attacgacta cgctgattaa gtgcaggtag ttcgattcgg ataggtattc
    11521 ttcgaatgaa agttgttaag aaatgactag taatctcttc agtcgtagca aaaaagagac
    11581 gtgttttgat ccggcgtgac aaattaggtt ctcccatacg ataaatcaca ccttgatcaa
    11641 gataggtgaa cagtttttcc tgaccttctg gtgttaagcg atgtacctcg tctaaaaaca
    11701 agatcccacc atctgctgct tcaaaagccc cttttttatt ttcttctgca ccagtgtacg
    11761 ctcccttaac atgtccaaac aaattgctag tcaaaagttc aggattatct gcatattgtg
    11821 cacaattaaa agtgatgaat ggtgcagaat cttctagcag atcatgaagc agacaatact
    11881 gatagaccaa attaactaaa taacttttac ctgtgccact ttcgcctgta atcaaaagtg
    11941 gtaatccgcc atctggatag taaagagctg ttttgatttg ttcgatactt tctttcaaac
    12001 tggcgtcgta tccgatcata aaagagaata agtcttttgg ttgcgcgaaa aaaggctgtt
    12061 cctctttgag atcatcgata gaaaaataaa aattcgtgcg taacttaaaa aattgttttt
    12121 caaaagcttc tttgtggaaa taaatcactg gtcgagaatt gattttgact agtagttgct
    12181 catcatttaa ctggttcaaa taatgactga ctgtgtttct ttttacccca aaatgatcag
    12241 ctaacctttg tgctgtaaag acctcgttca tatgttctaa atcgaaaaag gctgtctggt
    12301 tctctaagta acataaaatt tccttcttca acaacttatt cacccctcct ccatcataga
    12361 aaacggattc attttgtcaa taaaatcttt aataaagaat tgaaaaatat atcttattat
    12421 agacagcagc ctacttatcc cttataattt ttattctaaa aaacgtacag ttccttccag
    12481 tttttatact ggaatttcaa catatgaaag aataaggagg ctatgactat tcaatgaaat
    12541 cggataaata taaaaacagg aaacatactt cctggaaaac ttttcgagaa atcatcggat
    12601 cttatctcgc tgtagttgta tttttgcctt tgctttatat ggctatgaca gaacaaactc
    12661 gttttattgg cgtagatacg caatatatag ccgaaacagg atttttattc atctttatct
    12721 tgatttttgc gttctataaa tccttccata caaaataaga ttcacagatt tcaactttcc
    12781 tgtctgtttt tagctattac aaatccttat atgtggtata acaacaattt attggcataa
    12841 tgaggaaaaa cgagttatga tgctttcaga gagtaaagag gtactgttgt caccatcctt
    12901 tttattgatt acgtacacca ctcttagttt tttcccattg attacgaaaa caaggtagaa
    12961 acattgatgt tcctaccttg ttttcttttt ttattttcag atcaaaatct caagtagctt
    13021 ttgacttgat gtcgggaggt tgtcttcgtt ccatcaaacc tgatagaatc tgcgccaaac
    13081 catagttttc tccactatta tttattcctc taagatagta cccacaataa acgaataaat
    13141 atttttctca ttttcatact ccttctttga aaatcaatta gatttctctc aacccacttt
    13201 tttacaaaaa ttacgtagca aaaaagattg caagaacaaa ttaaaaaaga agtaaataga
    13261 gtttcatcta taaacattta cttgatatat tttttatgca gaattcattt atagaaaaat
    13321 taagtaaaat agacgttcct atgaatgaag agactggcat gttttctcat tttctttttt
    13381 ttaaaaaaaa tagtctattc aatttctaaa gcttcttcat aataaaactt tcatttatga
    13441 aaaggcttgt tctcttttca ttctaaattt cctaagctac aatgtggtag tacttgtttt
    13501 ttcaattgtg gacaaataaa taataggagg aatcatatga ttcagttatt acgttatgca
    13561 aaagactatc gtaagcaaat cattttgggc ccgttcttca aatttcttga agctgtcttc
    13621 gaacttgtcc tgcctttaat gatggcttcc ttgatcgata atggactaaa aatgaatgac
    13681 cgaggaaaaa tcattgaaat gggcttatgg atggtcgcta tgtctgtgat tggtctgatt
    13741 tgtgctatca tttgccaata ctatgcttca gtagcttcac aaggatttgg tacagagtta
    13801 cgtaatcagc taatcaaaaa aatcaatact ttctctcaca acgagttgaa tcattttgga
    13861 acagatacct tgatcacccg aatgacaaac gacatcaatc agcttcagct agctttagca
    13921 atggtcattc gtttattgat cagagcaccg tttttaagta tcgggtcagt ggtcatggct
    13981 tttgtgatcg actgggaagt aggtctgttt ttcttagcat tattgcctat tttctcaatc
    14041 attttatttt ttatcatcaa aaaaaccgtt cctctctacc aaaaagtgca agaaaaacta
    14101 gatcagctca atgaacacgt tagtcagaat cttagcggtg ttcgtgtcat ccgcgcattt
    14161 gcgcagacaa aaaaagaaac agagaagttc gataaaagca caaatgatct agcgaacaat
    14221 tatttacgtg tttccaatat ctctgcccta ttatcacctg ctacaacctt gatcatgaat
    14281 gtcgggatca tctgtttgct gacagttggc gggatcaaag taaatattgg tagcttgcaa
    14341 caaggacaag ttcttgcttt gatcaattat atgaatcaaa tgcttttggc actgatcgtt
    14401 gtttcaaacc tcgtcgtgat cttcacacgt gccgaagctt caggaaatcg ggtgaaagag
    14461 gtgctagaca cagaaaattc gattcttgaa gctgaggtca gtactactcc cgatttttct
    14521 tctgaagcaa ttatcgcttt tgaccatgtt gacttccgtt atactcctga ttctggtctt
    14581 tctctccaaa atattacatt tcagctgaag cgaaatacag tccttggaat cattggtcca
    14641 accggaagcg ggaaaacgac tttgacacaa ttgattccgc gtttctatga tgtcagttcc
    14701 ggtacagtta taatggacgg aatggatgtt cgttcttggc agctggatca tctccgtcag
    14761 caaattgctc ttgttcccca aacttctgta ctatttaccg ggactattcg tgaaaacctt
    14821 caatggggta agaaagacgc cacagaaaaa gaatgttggg aagctctgaa aatcgctcag
    14881 gcagaagaat ttgtccgtca gcttccaaat ggtttagata caaaagtcat ggaaaatggg
    14941 aaaaatttct ctggcggaca aaaacagcga ctgacgattg caagagcttt gattgccaag
    15001 ccagcattac tgattttaga tgactcttta agtgcgttgg attatcaaac agacttggat
    15061 ttgcgtaagg cgctacagac ttatcttggc agtacagtga ttattatctc ccaacgtgtc
    15121 cgctctattc aagaagcaca tcatatctta gtgatggatc aaggtaagat tgctgctcag
    15181 ggtacccatg aagaattact tgctcaatca gcagaatatc aggaaatcgt cgcatcacag
    15241 gaggaagaat agttatgaaa gtaaaaaaat tatccttgca gacgctccgc cgattcattc
    15301 cttaccttac tgcctatgca aaagacattt ggctagctgt gatactagga atcatcaatg
    15361 ggattgcaac agttgtgatg acgttacaaa ttggtcaaag tatcgatcaa atgattggag
    15421 aaggacaggt ccgcttcaat cgactgttcc atttacttat tctattcggt ggtatcgttt
    15481 taatcaacgt agtcagtcaa tggctcatcc aagtgttaag caatcggtta gcttacttat
    15541 ccgttgcaaa attaagaaaa gatgcatttg ctcatctgaa tcgattgcca cttcgttatt
    15601 atgatcaaaa ctcccacgga aatatcgtca gtcgatttac aaatgatatg gacaatattt
    15661 ccattgcaat ttctgcggcc ttcaatcaat tattttctgg agtggcaatc atcattcttt
    15721 cgtttatttt tatgatgcgt ctaagtccac ttctgacatt ggtcgttctt tgttctacac
    15781 caattatttt ccttgtgagt tggatcgttg ctcgtgcttc acaaacaaat ttcgatagac
    15841 agcaaaggat tattggggat atctcgggct ttgtgaccga acgaatcggt aaccagaaaa
    15901 tcgtgaaagc ttttcagcaa gaagaagcta gtcaacagca atttgaactg ctaaatgctg
    15961 atctatatga aaaaggacaa cgggcacaat tttcttcttc cttgacaaac ccgtcttctc
    16021 gttttgtaga tcaccttgct tatttatcga ttggtttagt tggcggccta ttggcattga
    16081 agagtggttc gtcaatcact gttggtgtga tttccagctt tacgatctac tcaagtcagt
    16141 tttctaaacc atttatcgaa ctttctggaa tcacgacaca actgcaaacc gctttttctg
    16201 gtctagaacg agcatttgat ttgatcgatc agccagaaga aaagcctgat ttgccagatg
    16261 cctatgcctt ggaacccaaa aatatcaaag gaaaagtctc ttttgatcat gtttcttttt
    16321 cttatgaccc caagcagcgt ttgatcgaag atttcaattt tactgcttat ccaggtcaaa
    16381 ccattgctat agtaggaaaa acaggggccg gaaaatccac acttgttaat ttgctgatgc
    16441 gtttttatga cacaacaaaa ggaacaatta cagtcgatga ccatgacatc cgctctatcc
    16501 aacgtgatac attacgtaaa agttttggaa tggtgttaca agatacttgg ctatttgaca
    16561 gtacattgcg agaaaatctt cgttttggga atccggaagc aagtgacgca gaaatcaatg
    16621 atgccctaaa agcctcttat atgtatgaat ttgtagaacg tttgccggaa aaattagata
    16681 ctaagattgg cggtcaaggg ttaaagatat cagatggaca acgccaactg ttgacgattg
    16741 ctcgaacgat gatcagtaat ccccctatgt tgatcttaga tgaagctacc agctcagtcg
    16801 atacattgac agagaaaaaa atccaacaag ccttcttagc aatgatggaa ggaaaaacca
    16861 gttttgtgat tgcccatcgc ctgtccacaa tcaaaaatgc ggaccagata ttagtgatgg
    16921 atcagggagc tattgtcgaa atgggcaccc atgatgagct gcttcaaaaa gatggttatt
    16981 accgacggct ctatcaagca caattcacag cacaataaaa acaagcagtc ttctgggatg
    17041 ggaagactgc ttgtttttta ggctctatac tttttgatgt tggtgaactt caccaacatc
    17101 ttttttgtat aaaaaaatat agaaaagaca ccctgaaatc ctttagaatt aatttggcta
    17161 ccaattcata ggaggattca agatgtctca tactcagctt atcaaagata ccctaaatat
    17221 tctagaccta aatatctatt tcgaggaaaa ttgtttaact aaagaaaaat acaaagggca
    17281 aatttgcttg atttacaaag gaactcttct gtacaagcca gaagagtgtt cccattgtct
    17341 ttgtgtcgtc ccctctagga tcattcgttg ggggacgaca accgttcggt tgttactgaa
    17401 tgatgtgtct gagtatcgca cttatctgga gctgaagaaa caacgattta aatgtaagtc
    17461 ttgccaaaga acattcgtag cggatacctc tgttgctgaa aaacactgtt tcattagtca
    17521 aaaagttcgt tggtctgtca ttgctcgctt aaaagagaat acttccatga cggaaatcgc
    17581 tcgtcagaaa aatatttcca cttcttcggt ctatcgtgtc atgaagcgat tctaccgccc
    17641 attgaatcct ttcaaacaga ctttgccaaa ggtcttatgc tttgatgaat tcaaatcggt
    17701 tcgaagtgtt gccagtgcaa tgagttttat catgatgga
//
LOCUS       DADQCX010000060        17587 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.060, whole genome shotgun sequence.
ACCESSION   DADQCX010000060 DADQCX010000000
VERSION     DADQCX010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.060"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            363..731
                     /locus_tag="J8R83_001836"
     CDS             363..731
                     /locus_tag="J8R83_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAZ9574966.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            911..1852
                     /locus_tag="J8R83_001837"
     CDS             911..1852
                     /locus_tag="J8R83_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAZ9574967.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1921..2652
                     /locus_tag="J8R83_001838"
     CDS             1921..2652
                     /locus_tag="J8R83_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAZ9574968.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2796..4976
                     /locus_tag="J8R83_001839"
     CDS             2796..4976
                     /locus_tag="J8R83_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAZ9574969.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4996..5478
                     /locus_tag="J8R83_001840"
     CDS             4996..5478
                     /locus_tag="J8R83_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAZ9574970.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5494..6255
                     /locus_tag="J8R83_001841"
     CDS             5494..6255
                     /locus_tag="J8R83_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAZ9574971.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6386..7720
                     /locus_tag="J8R83_001842"
     CDS             6386..7720
                     /locus_tag="J8R83_001842"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAZ9574972.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            8027..8512
                     /locus_tag="J8R83_001843"
     CDS             8027..8512
                     /locus_tag="J8R83_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAZ9574973.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8505..9188
                     /locus_tag="J8R83_001844"
     CDS             8505..9188
                     /locus_tag="J8R83_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAZ9574974.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            9314..11959
                     /gene="polA"
                     /locus_tag="J8R83_001845"
     CDS             9314..11959
                     /gene="polA"
                     /locus_tag="J8R83_001845"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAZ9574975.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            12004..12840
                     /gene="mutM"
                     /locus_tag="J8R83_001846"
     CDS             12004..12840
                     /gene="mutM"
                     /locus_tag="J8R83_001846"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAZ9574976.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12804..13433
                     /locus_tag="J8R83_001847"
     CDS             12804..13433
                     /locus_tag="J8R83_001847"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAZ9574977.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13485..13817
                     /locus_tag="J8R83_001848"
     CDS             13485..13817
                     /locus_tag="J8R83_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAZ9574978.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            14129..14620
                     /gene="nrdR"
                     /locus_tag="J8R83_001849"
     CDS             14129..14620
                     /gene="nrdR"
                     /locus_tag="J8R83_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAZ9574979.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14643..16016
                     /locus_tag="J8R83_001850"
     CDS             14643..16016
                     /locus_tag="J8R83_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAZ9574980.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            16016..16942
                     /gene="dnaI"
                     /locus_tag="J8R83_001851"
     CDS             16016..16942
                     /gene="dnaI"
                     /locus_tag="J8R83_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAZ9574981.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            17071..17511
                     /locus_tag="J8R83_001852"
     CDS             17071..17511
                     /locus_tag="J8R83_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAZ9574982.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5992 a         3067 c         3866 g         4662 t
ORIGIN      
        1 agaaagaggt cgtgagcctg ccgtttcact ctgagtcaca aagagcaatt tcaaaaaata
       61 gcttctcatg tttgttgaat attgtgtctt gtgaccgagg agttgtcagg agaacaccgt
      121 ttaccagagg ttgtgacttg tttttagtca cgacctcttt ttttatttat tccatataaa
      181 tacacattat ttattccgaa aagtgaaagc gcaaataaca aaaacaacca acttatttat
      241 tattaaagaa aagcgtattt aagtaggacg attctgttga gagctttcgt agattttccc
      301 attttcctat ggtaaactga caaagttgag aatgttagaa cagatcgttt aggaggaaac
      361 agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa
      421 cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat gggacgctta
      481 taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat cgagcatttg
      541 ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt tacagtaaag
      601 atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt gatatggtac
      661 agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac tttgcggtta
      721 caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt
      781 tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat tatacacaag
      841 caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa aagaaggaag
      901 gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa tcgaagaacc
      961 agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta aaggtcgtat
     1021 tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa acacgactgc
     1081 ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca agatcgatcc
     1141 aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc ttgtaagttt
     1201 aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt caccgcaaga
     1261 atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga atgattatga
     1321 atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt ttcgagagct
     1381 tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag tgacctactg
     1441 tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag gattcaaaga
     1501 tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag tccaaggaga
     1561 attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata tcaaccaagt
     1621 agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac gatatatcaa
     1681 ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca
     1741 tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca
     1801 tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat agaaaacaat
     1861 agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat ggtgatccac
     1921 atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct ttttgaaaaa
     1981 cttattcact attatgatcc aaagatccat cagcttgttt tattagggga tctcaatgat
     2041 cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga agaaacagga
     2101 gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca atcaccggag
     2161 gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac
     2221 ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca atcgagatat
     2281 tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga aaattatctt
     2341 tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag tctaagagac
     2401 tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa gacaattgta
     2461 tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga cctctggatt
     2521 caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt gcatggggtt
     2581 gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga aggaccttgg
     2641 catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg ctctttttat
     2701 ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt atgatagaat
     2761 aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg aaccagacga
     2821 tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg actactgtac
     2881 ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga aaagaaatga
     2941 ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa
     3001 acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg aaactgactc
     3061 ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa gatttgtatc
     3121 gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa ggacttgaac
     3181 cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa gcagaaaaat
     3241 atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt gctcatgaga
     3301 ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg tcttatacgt
     3361 ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa aaaggcgtat
     3421 atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat cgaatattag
     3481 ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta gatgaagcag
     3541 caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat
     3601 tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca atcgagcgag
     3661 aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa
     3721 acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg ggatttgatc
     3781 cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa gttttagcaa
     3841 tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct gctggaccag
     3901 cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga aatggtacag
     3961 ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac cataaaacct
     4021 attacgctat cgtcaacgaa gcaggcgctt ctgtttactc cgctagcgaa attgcacgaa
     4081 aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc
     4141 aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc
     4201 aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg gaaacagcgg
     4261 ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag catatatcag
     4321 gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac ggagaattca
     4381 ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat gaacaagcaa
     4441 tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt atccatcccg
     4501 aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa aaagagcttg
     4561 gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg gctgaaagcc
     4621 tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa cctggacgag
     4681 atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt atggaagact
     4741 tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc ggcgcatttg
     4801 ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc aaaaaattcg
     4861 tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg atagaacaag
     4921 tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa gagtaacaat
     4981 gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga gatatcatta
     5041 aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt acgtacaact
     5101 ggcgggcgct atcatttaaa cgatcatcat ttagatttta atgcgaagct atttgaagag
     5161 tcagacgaag agacgattgc aggaatcatc aaacatgaac tttgccatta tcatcttcat
     5221 ctagctggaa gagggtatca gcataaagat atggatttca agtatctttt gaaaaaaaca
     5281 ggagggttgc gctatgcacc agccttgacg aagaaacaga taaagatgga gtattatcga
     5341 tgccaagatt gttctgccac gatctgccgc aagagaagaa tcgatgtacg caaatatcgt
     5401 tgtggaagat gtcatggaga aatcaaatgg attgagacaa aaagagaaga ctttaatgaa
     5461 gcacaaaaaa tcagatgaaa ggatagaagg cctttggaaa aaagtgagca gaggaatcta
     5521 aaagactgga atcagctatt aaatttttta gccgcacctg aagagggaaa ttttgaggaa
     5581 ctgacggcac ctacacttat tttagctgga aactgtcttc ctatcttagc tgataaagca
     5641 gcacaaatgt atttaaatgg ccaagtagat caattgtttt tggtcggagg ggtggggcat
     5701 gcgactagaa tcctttatga gaattttgaa aagcaaggat ttcattttga agatggcatg
     5761 agtgaaagtg aaatctgtcg tcagtatcta aaagaagtct atgatttgcc cgataaggct
     5821 tttctgatag aatcgaagtc tacaaattct ggagagaacg ccactttttc actggagatt
     5881 cttcattcct taggagctgt accagaaaaa atcttattga tgaatgatcc gacactgcaa
     5941 cgcaggactc gagcaacttt tgagaaagta tggcaaaatg aacaaactat tttcgcgaat
     6001 gctgtgccat ttgtgccgga aatccttcac ttttctgaag agatcatctt tacagcaaaa
     6061 gaactgaatc atcaatggcc taaggaatat ttccatgcgc tagtattagg agaaatggaa
     6121 cgtctccatg acgatgagaa cggctatggt ccgaaaggaa aagattttat tcctcacatt
     6181 gatatatcag aggaagtttg gtcttcttac accagaatta aagagtcaat aaaaacggat
     6241 ttttctcgta cttgaccatt ttagcaagcg aatcctcctt tccaaataaa tttggttgaa
     6301 attttcaatc gtttataaga taatgaggag cgtgttgaat gtaatagcta aaagaatgga
     6361 cgctagataa gagaagagga ttcaaatgga aaatcaaaat aaattgtatc attttgttgg
     6421 tatcaaaggt tcaggaatga gctccttggc tcttgtttta catgaacaag gtctaaatgt
     6481 ccaaggatca gacattgaaa aatatttctt tacacaaaga gatttagaaa aagcaaatat
     6541 cacgattctg ccatttaacg cagataatgt aaaaccaggg atgacgatca ttgcaggaaa
     6601 tgcatttcct gattcacatg aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat
     6661 tcgctatcac gactttattg gtcattttat ccaaaattat acgagtatcg ctgtaacagg
     6721 ctctcacgga aaaacaagta cgactggact gctctctcat gtattgagtg gtgtccgtcc
     6781 aacaagttat ctaattggag atggaacagg acatggtgat ccgcaagcgg aattcttttc
     6841 atttgaggcc tgtgaatatc gccgtcattt ccttgcctat tcaccagact atgcaatcat
     6901 gaccaatatc gattttgatc atccggatta ttatacaagt atcgacgatg tatttacagc
     6961 tttccaaaca atggctggac aagtgaaaaa agctattttt gcgtatggtg acgatgctta
     7021 tttacgcaaa ttaaaagcaa atgtgccgat ttattattat ggtgtcacag aaaacgatga
     7081 tatccaagca cgaaacatcg aacgcacaac ttctggttct gcttttgatg tctatcatgg
     7141 ggatgaattt gttgggcact tcactgtacc agcattcggt aaacacaata tcttaaatgc
     7201 tttaggtgtt attgcagtag cttatttcga aaaactggat ctgaaagaag ttgcagaaga
     7261 aatgctgact ttcccaggag taaaacgtcg attcagtgaa aagatcgtag cagacatgac
     7321 cgtagtcgat gattatgcgc atcaccctgc agagatcaaa gcaacgattg atggcgcacg
     7381 ccaaaaatat ccagataaag aaataattgc agttttccaa ccccatacgt ttacgcgtac
     7441 gattgcattg atggatgaat ttgcagaagc acttgattta gctgataaag tttacttatg
     7501 cgatattttt ggttcggctc gggaagaaca aggaaacgtt aagattgaag accttggagc
     7561 gaaaatcaaa aaaggtggag aagtcatcaa agaaaataat gtatctccat tgttagatta
     7621 tcatgatgca gtagtaatct tcatgggtgc tggagatgtt caaaaatttg aacaagcgta
     7681 tgaaaaactt ttaagcagca cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct
     7741 tataaaaata gaaagagggg gagtggcaaa aatcttgcca agcccccttt tttgcaactt
     7801 atgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca
     7861 tgagaagctg ttttttcttg gctgttctta ttatttgatg caggacagct ttttcacgac
     7921 ctctgtaaac tataggaatc tgttaaatca agggagcaga acttgccttt tacgctactt
     7981 ttggtacaat aatgtatgat taaaaataaa ctggagggtt tctatcttga acataggtaa
     8041 gccgagaaaa ctaggaaaaa caataaatga aatcgaggaa ggcgactcgt tatccttaac
     8101 agaatctatt gaagataacc agcttttgct gtatttggga ttgacgaatg atgcaaatcc
     8161 tttgtatatc caacatgact ttgcacaaaa aacagaatat caacagccaa tcgttccatc
     8221 agtgatgctg atggggatca tcacaagtgc aatttcaaag catcttcctg gaccaggatc
     8281 acatgttgtc aatttttctg tcaattttat tgaaccggtt ttccattatg aaacactgac
     8341 ttttcagttt gaggtcataa aagtagataa gatgaaggat gtggtgacga tttctgtaga
     8401 agcggagaat acgaacgaag atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca
     8461 agttcctgaa ttggaaatag caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta
     8521 catcaatgtc aggtatcaat cgtttttatg caaaagttta tggattttta ggtatgggac
     8581 ttgcccttag tgcagtcact tcttacttgg ctctttgggt atttcctttg caattagcaa
     8641 cttttatcaa taattttcca ctaggctttg tgggtctgtg gatcgttgaa ctgattttag
     8701 taatggttct aggcgtaaaa gcacaaaaga atccgagctt agcaatcggt ggatttattg
     8761 cctactctct tttgaatggc ataatattag cggttactct tgcatactac gatattggaa
     8821 cagtaacgca agctttcttg acagctactt tgatgttcat ggggatgtct gttgtcggag
     8881 taacaacaaa aagagatctt agcggggttg gaagagcagg acaggcagct ttaatcggag
     8941 tgatcattgc actagtcttg aacatcttca ttttgagaag tagcgtagtt gagctgttca
     9001 tctccctact gttagtcgtc atctttgcag ggattacagc ttatgataac caaagcatcc
     9061 gtaatatcta tgtccagaca aacggaacag cacatagtgg aattgctgta ttcatggcat
     9121 tgaagctgta tttggacttt atcaacttgt tcttggcgtt tctgagaatc tttggacgga
     9181 acaactaaaa aagaaaaaaa ttcatcagtt ggggctatac cgaattattt ggtatggtcc
     9241 cgctttttct tttcgcattc cgcaggattc tttgttagaa tgaataagaa ctttacagta
     9301 aggagttaag aagatgacaa aaaataaatt attactcgtt gatgggaaca gtgtggcttt
     9361 tcgcgcattc tttgcgcttc acaattctct tgaacgtttc aaaaatagaa acggtcttca
     9421 tacaaatgca atctatgcat tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc
     9481 gactcatgtt ctggttgcgt tcgatgcagg aaaaacgact tttcggacag aaatgtatgc
     9541 ggagtacaaa ggtggaagat ccaaaacacc tggcgaattc aaagaacaaa tgccatatat
     9601 acgtgatttg ttgacaggac taggggtaca gtattacgaa ttgcccaatt atgaagcaga
     9661 tgatattatc ggtactttgg cagaaaaagt agacaaagat caatttgatg tcgtcgtgct
     9721 ttcaggtgat cgggatttga ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt
     9781 aaaaggtgtc agcgatatcg aaagctatac accagaacat gtagcggaaa aatatgatgg
     9841 gttgacgcca aaacagatta ttgacatgaa gggactagcc ggagatgcct ctgacaatat
     9901 ccccggtgtg actaaaatcg gtgaaaaaac agctatcaag ctattgaaac aatatggctc
     9961 agtcgaagga atttatgaac atatcgatga aatgaagcaa agcaaaatga aagaaaatct
    10021 gataaatgac aaagagcagg ctttcttatc gaaaaaattg gcgaccatca atacttcagc
    10081 gcctgtggat gtctctatcg actcattgaa gtatgaaggg aaaaatctcg ataaactcgt
    10141 tccgttttat aaagaaatgg atttcaatca gttcctttct aaattgaata tcgtagaaga
    10201 agaagtaaaa atggatgata ttttgtttga agtcgttcat gaattcaaag aggaaatgtt
    10261 tactacggat atggcgttgt acgtggaaat gatgggcgac aattatcata cagaggaaat
    10321 cgtcggagta gcgtggggga cagaaaagaa aatttatgtc acgaacgatc tatctgtatt
    10381 cgaaaaccga gcgttccatt cttggatcac tgatccgact cggctgaaaa aagtatatga
    10441 tgcgaaacga acttatgttg ctttaaaccg ctatactgga aaaacgaaag gaatcgattt
    10501 tgatgtcttg ctaggtgcat accttctcga tacgaatgaa aaaagcacag atatcgaagg
    10561 aatagctgct cattacggat acaacgatat ccaatcagat gaagctgtat acggcaaagg
    10621 ggcgaaaaaa ggtttaccag aagaagagga actctttttt gctcatttag cgcgaaaagt
    10681 agctgcaatc aatgcgttga caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga
    10741 agatcttttc cggaaaatgg aactgccatt gtctatcatt ttggcagaga tggaaataag
    10801 cgggatcaaa gtagatgcga ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt
    10861 aagagagatc gaacaaaaaa tctacgaaga agccggcgaa gaattcaatt tgaattcacc
    10921 aaagcaatta ggagtgatct tatttgaaaa aatgggatta cccgttatca aaaaaacaaa
    10981 aactggatat tccacagccg tagatgtact ggaacagctt cgtgaacaag caccaatcgt
    11041 agaggatatc ctcacctatc gtcaaattgc aaaaattcaa tctacctatg tcgagggact
    11101 gctgaaagtg atccaatcag atggaaaagt gcatacccgt tatgtccaga cattgaccca
    11161 aacaggacga ttaagctctg ttgatcctaa tttgcagaac atcccgattc gattagatga
    11221 agggagaaag atacgtcagg catttgttcc tagagaaaaa gactggctga tttattcttc
    11281 tgactattca caaatcgagt tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa
    11341 agctgccttc ctagaaggtc aagatatcca tgccagcaca gcgatgcgtg tatttggaat
    11401 cgaaaaggca gaggatgtca caccaaatat gcgtaggcag gcaaaagcag tgaattttgg
    11461 tatcgtgtat ggcatctctg attacggact ttcacaaaat ctaggaatca gccgaaaagc
    11521 agcacagcaa tacatcgata cgtactttga aaaataccca ggtgtcaaag aatatatgga
    11581 aagaatcgta cgcgaagcaa aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg
    11641 atatctgcca gacatcaatt caagaaatta caatatccgt tcttttgcgg aacgaacagc
    11701 tatcaataca ccaatccaag gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt
    11761 ggataaacga ttaaaagaaa caggtcttca agctacgatg ctgttacaag ttcatgatga
    11821 acttgtcttc gaggtaccgg aaaaagaact tgaatcatta gataaattgg tgaaggaagt
    11881 tatggaacaa gctgtttctc ttcatgtacc actgatcact gacagcagtt ggggaaaaac
    11941 gtggtacgaa gcaaaataaa cattgtttaa gacagagcaa tataatgaag gtgaaaagaa
    12001 aaaatgccag aattaccaga agtagaaacc gttcgtaaag gattggaacg gttagtagta
    12061 ggaaaaacga ttcaaaaagt tcaggtcttg tggcccaaga tcatcgagca accagagaca
    12121 cccatctttg aggcttctct tgttggcgaa accatccaat ccattggacg tagagggaag
    12181 tttttaattt ttcatctcga tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa
    12241 tatcaattta cgaaagaaaa tacaccaatc gataaacata cgcatgtact tttctttttt
    12301 gaggatggaa gccaacttcg ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc
    12361 gaaaaaggag caagtgcaac ttaccgagga atcatgaaat tgggacctga gcctttgcca
    12421 gatagcttct tattagcaga tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag
    12481 ccattgctgc tagaccaacg tctagtgact ggtctaggta atatttatgt agatgaagca
    12541 ttatgggaag cgaagatcca tccagaacaa ccggcgaaca cactgcgccc caaagaggta
    12601 gaacaattac gtctatcgat cattgatgtt ttggatcgtg caatagaagc cggaggtacc
    12661 acgattcgca gttatttgaa tgcattagga gaatcaggcg gatttcaagt agcactgcat
    12721 gtctatcagc aaactggcaa accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa
    12781 gtggcacaaa gggggacgca ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag
    12841 gatttgtttt aggtttgacg ggtggaatag ctaccggtaa aagtacggca gccaaagtct
    12901 ttcagtctca tggatttcct ttgatcgatg gcgatgtgat tgccagagaa actgttgagc
    12961 ctggaacgct tgctctgagg aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg
    13021 atgggcaact agatcgaggg aaacttggga tgattgtttt tccatcaaag gaaaaacggc
    13081 aaaaacttga tcagctatta gatccgttta tccgaaaagc gataaaagat caaatcgcct
    13141 ctctaagttc caatcatcct ttagtaattg tagatatccc attgctctac gaaggtcatt
    13201 atgaccacta tatggatgca gtagctgtcg tttatactac gccagaaact cagcttcagc
    13261 gtttgatgaa acgtaatcaa ctgacgctag aacaagcgca gcagagaatt agtagtcaac
    13321 ttccaatcga agaaaaaaag cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag
    13381 aaatacttgt gggacaaatc gaaaattggc tttttgctaa tcgctttctt tgagtatctg
    13441 tgtcaatttt gctatcctga gtatatagaa agtgagggat agcgatggga tcattaaaaa
    13501 atcaaaagga taaagtcgta ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag
    13561 aaaatctaat cgatgaaggt cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt
    13621 accaagcaag aatcgatgaa atagaagacc agcaggcaga agaagaagcg aagcggcaag
    13681 atttgactca agaacgaaaa aatccgacac ctgatcgtag taaaacaccg ctcccagaaa
    13741 gtgaccacat tcccgatgag caaaaaatcg aggaacagcg aatgaaacac tatacaggaa
    13801 tcgaagagaa gttataaaat agtaaaaaat cgagatgtga cttgaagcag atgagaaggt
    13861 gttcatctgc ttcaagtttt ttgtgctaga tgactaaatc agcttttgtg taagttattt
    13921 ctcagtaatc aaggtgatca gtattggaaa attgaaattt agtaaggaca ggggacacaa
    13981 ttacgcatga aagtagaaaa aattgttctt atatccgtgt tttttgggta ggacagtcgc
    14041 gtttgtgatt tgtttcgtgt tataatacaa ctagttgtaa agaaagacac atcctttata
    14101 taaaatgcga tgcaagaggt gagacaaaat gagatgtccc agatgtcaac ataataattc
    14161 acgagtaatc gacagccgtc aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg
    14221 tgagaattgt tcgttccgat tcactacatt tgaacgaatt gaagctgctc cgttattagt
    14281 aatcaagaaa aacggggaac gcgaagagtt caatcgcgat aaaattttaa gaggactcat
    14341 ccgttcagca gaaaaaagac ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt
    14401 cgaaaaccgc gtacgcagtc tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata
    14461 tgtgatggaa gatttagttg atttagacga aatcgcttat attcgttttg caagtgttta
    14521 tcgccagttc aaagatatgt ctgttttctt aaaagagttg caagatatcg tggataaagc
    14581 aaaagaaaat aataaagaga ataataaaga aaacaattaa gaaacaaaaa ggaggcattt
    14641 ccttggaaaa tgcttggaaa gagcttcaac caaaaaatat ttaccaagga agaaaagcgg
    14701 ctccgctgag agaagacagc aagaacgcct tgctgtatct ttatcagcca ctaatcggcg
    14761 gagaagcctt gagtatctat ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag
    14821 gtcctgaagg gatgcatgca gatctgctta gtagtctagg ctgcggtatc ccgcaatttt
    14881 atgatgcaag aaaaaagcta gaaggaatcg gcttactgga tgtttatttt aaagaagata
    14941 gtgatctggg acctcgtttt atttatgagc tgttagaacc actcattcct aaagcatttt
    15001 tcaaagactc tgttctggct tttcttcttc tggaaaaagt tggtgaacga cgattccaga
    15061 agcttaccca attctttgaa cctaaaaggc atacagcaga gggatatcaa aaaatcacaa
    15121 aaaaattttt agatgtttat cgcttcaatg aagcagtgta cgctgctaat caagaaaaca
    15181 tcgaatcgct gaataaatct tttgaagaat ctgaatcagt agcattactt gaagcagatt
    15241 cgacattcga ttggcagttt ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg
    15301 atgatccaat catcaaacaa gtcgacatgt atcatcagct ttacggtttc gatgaattga
    15361 cacttggcga actgatcagt caatcttatg actttagtga acaaaaagta tctgaaaaag
    15421 aactgcaaaa agccattttg gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag
    15481 ttgcggtttc tgaaaacagt aatgaaccct cgtcaaacga acatttgaca aacgcagcgc
    15541 ttcagctgat aaaagaagca cagagcattc caccgatgaa atatctggaa gcaatcaagt
    15601 cagaaaaagg cggatatgtt tctaaacaag aaaactggtt actgcaagat cttgtttctc
    15661 aatcaggtct ttccagtagc gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga
    15721 ataatgctag cttaaatgcc agttatgtaa atacagtggc aaatgaatgg gcacaaaaga
    15781 aaatcgccac agcagaagaa gcgatccagc acattcggca aataagtaat caagcaaaac
    15841 aatcaaaaca aaagaagcaa acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa
    15901 agcttcctga ttgggtcaac cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag
    15961 cagagattga ccgccgtttt aaagaatacc tggcaaaaaa ggagggtgat atctagtgga
    16021 agacgtaggc aaagaattga agaggatcat cagcaaacgc aattatcaag aaaagtatgc
    16081 tgaaatgatc gctgaagtct taaatgatgc ggatgttcaa gcttttctaa gcgcacacca
    16141 agaagaattg acacaagcgg atattgaaaa aagttacgct aaattgtatg aattcgtgca
    16201 agaaaagcgt aaatatcaaa aaaacgatcc aacgatgatc gctcccggct atgagccgaa
    16261 gctgacgttg aattttcatt atgtggatgt cacttatgta ccaacggaag cattgttagc
    16321 acggcaaaga caagaagaaa tcagaagccg agtaaaagca atggatatgc caaaagatat
    16381 tcaatcggct tcttttgaaa actttgaacg tacagatgga cgaggatatg cgagcttaga
    16441 agccctagat tttgtagaga aatatactgc tgatccaaaa gggtatcata aaggactgta
    16501 tctagtagga agttttggta ttggaaaaac atatttatta ggagcaacag cgagagaatt
    16561 agcgattgct ggattcacca cgacgctagt ccattttccg acatttgccg ttgagatgaa
    16621 acaggcaatc ggaaaagatc aagtggcaga aaagttagat gcagtgaaac gttcacctat
    16681 tttgatgatc gatgacattg gtgcagatgc gatgagtagt tggatacgag acgaagtatt
    16741 cggtgttatc cttcaatatc ggatgcagga acagttacca accttcttct catcgaattt
    16801 tacaatggat gaattggaac agcatttgtc cgtcactcaa cgtggagatg aagagccgct
    16861 aaaagcgaaa cggataatgg aacgcatacg ttatttgaca aaagaaatcg aaatgactgg
    16921 tcgcaaccga cgcaatggtt gaacagttga caagtccaac tgacatttga cctagtagta
    16981 aaagcaggtc agcgaatcat tatatggaca gaaatgaccg gagacaatca ccgcaacaag
    17041 taatgcagaa acttaaacgg aggatttttt atgagggcta ttttttctag tatatctgta
    17101 gttggtctat tttttctttt agcaggctgc ggtagcgcag atagcaacac aggttctgtt
    17161 gattcgattg atgcgggtca aacagtaaaa acaagcagta cgaaaacgga gagacaaagc
    17221 atatttgtcg gaacgattga aagtatcact caagtagaag cagaagaaga aacgcttcag
    17281 ttgaaactcg tcgatgtcat ggccaaagaa gatccagcga atatgggaac gtcattcagc
    17341 aatgacggag tgatcttaaa tgctactgct gaaaaaataa gcgtggacat aaatgaattg
    17401 aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac gatgtctatc
    17461 ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata accaataaca
    17521 ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt tttaaggaga
    17581 tatggga
//
LOCUS       DADQCX010000061        17328 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.061, whole genome shotgun sequence.
ACCESSION   DADQCX010000061 DADQCX010000000
VERSION     DADQCX010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.061"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(99..644)
                     /locus_tag="J8R83_001853"
     CDS             complement(99..644)
                     /locus_tag="J8R83_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9574983.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(656..1348)
                     /locus_tag="J8R83_001854"
     CDS             complement(656..1348)
                     /locus_tag="J8R83_001854"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAZ9574984.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1367..1651)
                     /locus_tag="J8R83_001855"
     CDS             complement(1367..1651)
                     /locus_tag="J8R83_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9574985.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1664..2227)
                     /locus_tag="J8R83_001856"
     CDS             complement(1664..2227)
                     /locus_tag="J8R83_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAZ9574986.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2455..3117
                     /locus_tag="J8R83_001857"
     CDS             2455..3117
                     /locus_tag="J8R83_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAZ9574987.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3241..4437
                     /locus_tag="J8R83_001858"
     CDS             3241..4437
                     /locus_tag="J8R83_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAZ9574988.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4538..5914)
                     /locus_tag="J8R83_001859"
     CDS             complement(4538..5914)
                     /locus_tag="J8R83_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9574989.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5951..6817)
                     /locus_tag="J8R83_001860"
     CDS             complement(5951..6817)
                     /locus_tag="J8R83_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAZ9574990.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6906..7931)
                     /locus_tag="J8R83_001861"
     CDS             complement(6906..7931)
                     /locus_tag="J8R83_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9574991.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7949..8623)
                     /locus_tag="J8R83_001862"
     CDS             complement(7949..8623)
                     /locus_tag="J8R83_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9574992.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8807..9700)
                     /locus_tag="J8R83_001863"
     CDS             complement(8807..9700)
                     /locus_tag="J8R83_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9574993.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9774..11471)
                     /locus_tag="J8R83_001864"
     CDS             complement(9774..11471)
                     /locus_tag="J8R83_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9574994.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11464..12777)
                     /locus_tag="J8R83_001865"
     CDS             complement(11464..12777)
                     /locus_tag="J8R83_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9574995.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12777..16814)
                     /locus_tag="J8R83_001866"
     CDS             complement(12777..16814)
                     /locus_tag="J8R83_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAZ9574996.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16827..17285)
                     /locus_tag="J8R83_001867"
     CDS             complement(16827..17285)
                     /locus_tag="J8R83_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9574997.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4853 a         3893 c         3018 g         5564 t
ORIGIN      
        1 aaaataacgt ataaaaaaga gcataaaaca aagtcgtttg ttttatgctc ttcttttatt
       61 attttgtgct ttttatttta tcaaatcact ttgttttttt ataaaatttc tgcgcctagt
      121 gtggactcaa aatgtctcaa tgcccattca tgtccaacgg gatcgaaact tgccacggaa
      181 tctttgaaaa tatggagttt gtatcctaga ttatacgcat cgactgctgt atgcaacaca
      241 cagatatctg tacatacgcc ggtcaaataa atatctgtga tctggcgttc tcgcaaacgg
      301 atgtctagat ctgttccact aaaagcggaa taatgccgtt tgtctatcca ataaacattt
      361 tcctcttgct catagtcttg gtataaactt tttaaagagc cgtacaattc ccgtccaccc
      421 gttcctatca cattatgcgg aggaaataag cggttctccg gatgaaagga atcttttgga
      481 tcatgcgcat caatggcaaa aacgacaaaa tccttttgat caataaactt ctttgtatga
      541 gcagtcagct ttttttcaat tacttgtcct gctgtcccag tagtcagctt tccatcctct
      601 gcaacaaaat catatgtgta gtcaatcgag atcaatgcgt tcatcttagt cctccttata
      661 cgagatgttt gacaaattcg atcaccattt ctgctgatcg tttgcctgcg tcttcgataa
      721 attcgtcaaa gctttgtgtc gccgagtgat ctgctgtgtc gctcattgca cgtacgatca
      781 aaaatgggat attgaactga cgagctgttt gtccaacagc ggctccttcc atttcgcaag
      841 ctaatgcttc agggaaattc gttaagattt ctttgatttt atctggcgag tcgacaaatg
      901 tatcacctgt aacgatcaat ccttcttttg cgttcaaatt cgttgctttt gctgctttaa
      961 ccatttcact gcgcaaatat gtgcttgctt cataatatag aggcattcct ggtaattgtc
     1021 ctgggttgta gccaaatcct gttgcatctg catcaaaata agctactttg tctgatataa
     1081 cgatgtcacc tacttgtaag ccttcaccga ttccgccagc tgaacctgta ttgatcacca
     1141 tgttcacgcc gtattgttgg atcaacagac ttgtggtaat agatgctaag acttttccta
     1201 taccggaacg tacgacgatc acttcgtggt tacctaatga acctgaaata aataaagcgc
     1261 ctgcgcgttc ccatgataat ggttcgctta ggttctctct caaaattttt acttcttctt
     1321 ccattgcgcc gataataccg attttcatct ttttaattcc ttctttctat ataaatgcga
     1381 ttgctaaaaa aaccacacat aacattagga taacaataat aagagatttc atcaaaaaag
     1441 agttccattt ggtcgtcttt tcccgttcgc tgatccttgt tttcgtgatt ggtttattct
     1501 ttttgctttc tttacgataa aagctggcaa tctttttttc ttcttgctga taagctgttt
     1561 ctgcttttcg ctgttttttt aatgactcgc ttgcttgtgc ttgttgtcgc ttgcgaagtt
     1621 cgcttcgcgt aataagcggt cctttggcca taagccgatc cctctacttt cctttggtca
     1681 atagttccca gtattgaatc gcataaatcg tctttgcatc acaaatcaac tgatctttca
     1741 tcgcttgttg cgcctcttca agagttagat gatacaactc cagtacttcg tcttcatctt
     1801 gtgctaaagg attctcgacc ttctctaccc cttgtgcatg ataaatatga aggacttcat
     1861 ttgcaaaacc tggtgaaaga tacatcgaag taagatggct cagcgacttc gcacgatagc
     1921 cagtttcttc ttctaattct ctagctgctg tcatttcggg attttgtcct tctcctggat
     1981 cgatttttcc agctggaatc tccaaaatca ctttttctaa aggttttcga aattgtttga
     2041 caagaagcag acgatcttgt tcgtcaaaag caatgatccc gacaccgcca ggatgaaata
     2101 ccagttctct cttcgaagtt cctccatctg gcaaacgaac ttcgtctaca gcaacatcaa
     2161 taatttttcc gctatagatt tctttgcgac tgattgtttt ttcttcaaat tgctcattgt
     2221 tcagcatatc ttctcctgct ttctttgtaa tcataactgc ttttttttca tttttcaatt
     2281 tttctcaaaa actccttatt agtttaccat agataaacct tagattttct ctaaatatag
     2341 aaaatccttc tttagtccga tactctttct agtagtccgt atgctaaaat aagtatgtaa
     2401 tcgaataacg aaaagaattc aatactcaac gataaatgac atggagggtt tattatgata
     2461 aaacgaaatt ggccgtggct tctagcattg gtcttgctat ttctctttgt ccgaaacaat
     2521 agtttttctt ttgttctagg acttttattg ataggtgtag ttttagtttt gtggggactc
     2581 tttggttcgc gcaggaaaaa gggaaaacaa gaagaaattc ctgcactgac tgacgaactt
     2641 gaaactcact atgaaaaaag cggtatgaca gcgaatgaaa tttcattttt tcgacaaaca
     2701 atgaatcaaa caaaaaatga gatcaatcaa ttgcaaatga atatgcagca gacagccaaa
     2761 cttaaagcaa tcgatctccg ccatgatcca gtcaaagcag cgaaagcttt attcaaagaa
     2821 ttggtgaaag aaccaaaccg actgcatgaa gcaagtcagt ttctttatac gcatctgccg
     2881 aatctagttg atttgacaaa taagtataat gagatcaatg accatgagat caaaaacaaa
     2941 cagacctatg aaaaactaga agaaagcgcg cagatcatcg accagctgtc agctttaatc
     3001 gcacaagatt atcaaaaatt cgttgctgag gatctagatg atatcgacgt agagatatct
     3061 gttgcgaaac agagcttaaa gcgtgataat aaatatgaac cagaacaaaa ggattaactc
     3121 ttttgttcat aaaagaagac tcggaacatt cagatgatgt ctggctgttt cgagtacttt
     3181 ttctaaagta gagacattca tgtaagaatc gagaacagat tcaacaagga ggaatttttt
     3241 atggatcata aaccgactga aacaaaagat gttacaccag ttaacgatac acttgaagat
     3301 ttattgaaca acccgttttc aactccaaca gatacgctga ccacttcaca acaagcggag
     3361 attgatcagc tccaagagca acagacagct gctcgtttaa ttgacaaact accggcggaa
     3421 cgccaagaac aagctaaaca gctagcagca aaaatcgatg ctaatgatgc acagtctgtc
     3481 atcagctacg gatcggctgc ccaagcaaaa ttaagtgaat tctcacaatc gatgttgaat
     3541 catgtgcaag cacaagatat tggtcctgta ggagattcct taactgaact gatgtatcgt
     3601 ctccaagaag ccaatcctga cgaactgcgt gccggagaag ggaacatctt ccagcgtgtc
     3661 ttcgggaagg tcaaacaatc gatctatgaa gtgacagcaa aatatcaaaa gattggtgca
     3721 caaattgaca agatttcagt gaaattagat aaagaaaaag acggtctgct aaaagataat
     3781 ctgatgttag aacagcttta ccagaaaaac aaagactact ttgatgcact gaatatttat
     3841 atcgctgctg gagaattgaa aatggaagaa cttcaaacaa cgatcattcc agaagcgatg
     3901 aaaagagcag aagaaactgg cgatcagatg gatgttcaga ttgccaatga ttacacgcaa
     3961 ttcctagatc gtctggataa acgtacgcat gatcttcgct tagctagaca gatcacgatc
     4021 cagcaagcac cacaaatccg tttgatccaa aacacaaatc aggccttggc tgaaaagatc
     4081 caagcatcta tcgctacagc cattccgctg tggaaaaacc aagtcgtgat cgcattgacc
     4141 ttgcttcgtc aaaaagatgc agtaactgct caacgccaag tctctgaaac aacaaacgac
     4201 ttattgaaga aaaattcaga aatgctgaaa atctcagcca tcgaaacagc gaaagaaaat
     4261 gaacgtggaa tcgtggatat cgagaccctt caaaccactc aaaatgattt gatcgaaaca
     4321 atccaagaga cattgcgtat ccaaaaagaa ggaaaagaaa aacgtcgtca tgcagaagta
     4381 gagcttggac acatggaaga agatctgaaa caaaaactgt tggatttaac ccaatagatc
     4441 acctttcgct tgttactaaa acaaacgccc aacaacagtt tattacaact gttgatgggc
     4501 gtttttctta tctttcttct aacttctcca ttggagtcta tttctcattc atcttgctgt
     4561 gtccatagcc atagccaaaa taaatgatca gtccaataac cattacgata ccgaacacga
     4621 tccatgtcac agtttgcaga cgaagcatca atacaataca agtcaagatg gagacgattg
     4681 gcaatagcgg aacgaatggc actttgaatt ctccagcttt tggtttgcca aacatttttc
     4741 tcaacttcag taagcctaga ctaacaagca tcaaataggc gagcgccatg atattcgtta
     4801 gttccgctaa tacattcaat gggaaaaatc cggcaaagaa tacagctgcc acaccagcgg
     4861 cataagtcgc ttttttcggt gtacgatgct tttgatcgat ttctgtcata aacttaggaa
     4921 gtaagccatc cttgctgaca gcaaacagta aacgagcaag tgaatacatc atcgagatcg
     4981 ttaccgtcag tagcgttaaa attgccccta cagcgatcac cgcgcccact gttccatgtc
     5041 ctacatacct cattgcaaaa gccactgggt cattgactcc tagttcagta tacggaacga
     5101 ttcctgtcaa gatcagcgtc acgatgatgt aaaggacagt agcaatcagt atcgaaccaa
     5161 tgattcctct tggcacatct ttttgcgggt ttttgacttc ctcggctgcc attgcaacgg
     5221 catcaaatcc caagaaagca aaaaacacaa gagctgcacc atctagcaca ccggaaaaac
     5281 caaaaggcat gaatggctgc cagttatcag gtttaacgaa aaatattcct acaatgataa
     5341 acaacgcgat gataccaaat ttgacatata ccatggcatt attcaaacgt aatgctttct
     5401 tggcttcaag cgacacgatg taagtgacga atatcactac gagcaccgca atcaagtcaa
     5461 tgtatgtacc attttccgga ttgtacccgc cagttaatgc ttgtggaagt tcggccccta
     5521 aacttttcaa aaaaccttgc atatagccag accatccgga agcaacagag gaaaccgcta
     5581 gtaaaaattc cccgatcaac aaccaccctg tcagccaggc agcaaattca ccaaatacaa
     5641 catacagata ggcatatggc ccaccaatca ctggcactcg cgaagcaaat tctgcgaaac
     5701 ttagtccaga caaaatgaca acgattgcag ctaagacaaa tgaaagtgac agtgctggac
     5761 cagcattttg attggccgca acccctgtca ccacaaatat tcccgtaccg atgatcgcac
     5821 caattccaag catgatcaaa tcagacgttt ttagttcttt tttcatctca ctcgtatgat
     5881 tgagattgat ctctttctta cgaaacaaat ccattgaagt tcctccccat tttaggttgg
     5941 aaaacagcga ttaaactgtt ttcatatacc ctaaaaggat accacctaaa atgactaaaa
     6001 ggcaaccaac aataacataa atgagctctt ttttcgtttt tctttcgcca aggatgaaaa
     6061 tcccacctaa agtagagata atgatcccca tttgtgaaag tgagaagcca acagctaaac
     6121 caagtgattt gactgttaga agcatgcaga tgtttcctaa gccccataat aatccacaga
     6181 tcatgttttt ccacacaaac tgatcgactt taactttacg gaaagcaaag aagcttgcgc
     6241 ctaagatcat tccgatactt tgaggtaaga taattgacat cgcatccaaa ttcgcccagt
     6301 tgacgatgat ggtatataca ccataaccaa tcgtagagaa gatcaatgct ctaaaaccct
     6361 taccaaaatc aagcatttta ttatctgtat ctatttttcc ttcgtcatct tgtcgggcag
     6421 tcaaatacgc accgcttaca agaagagcta aagcaataat accgtataca taatctttcg
     6481 tttgtgtcca ttcatggaag aaaacggctc ccgcaatcgt attcaaaatt aattgaaaac
     6541 cagtagacaa tggtagccct acagaaacac ccatgtactt cattccatgg aactgtccat
     6601 tttgtccaac actccaagct aagccggata aaaatccgat caagaaaatc caaggggtga
     6661 ttacaggact aacaacgaaa aagacaacta aagaaaacag aaatgcaccg atcgtcattc
     6721 ctagtgtttg ttgattggca tcgccaccaa ttttaccact tactaaacca atactacccc
     6781 atgccaacat agggactaat gctattaaaa tttccataac caatctcctt ttatttcaca
     6841 tgataagaaa cttatcagcg aaaacgttaa caacacaagc actttttttc gtttctaacg
     6901 attttctaac gtttttcatt ataaaaattt aagattggga aaaataaagt cattgttgtc
     6961 ccttttcctt cagttgattc agccgtcaaa tggataccta atttttcggc cagatttttt
     7021 gctaaataaa gtcctaatcc tgttgaatgt gttttgctaa gtcgaccatt tctcccagta
     7081 aatcccttat caaagatccg tttcaagtct tccgctggga taccgatccc tgaatcttta
     7141 actgaaaggc tgactccttg cgcttccttt tctatgctca caatgatgtt tccgtgatcc
     7201 ggcgtatatt tgatggcatt actaagcaat tggttgaaga taaaagcgat ccatttagca
     7261 tcggtcaaaa cagtatgatc ctcaccaacg atctcgtagc gaatattttt ttggataaaa
     7321 taatttgcct gactgcgtat cacaggctga atgattcctt ttagtccata ttcttggatg
     7381 aggtagtccc gcgagaaact gtcgagtctt gcataataca aaacttgttc tacgtattca
     7441 tcgatttttg ataattcatt ttctagtaat gtatactttt gatcgtcaat atcgaactcg
     7501 atcgaacgaa ctagcaattt agaagcggaa agtggcactt tgatttcatg gacccatgag
     7561 tcaatataat ctttttggtc ttgttgatta ctgattgctg attgcattac ttcttggtgt
     7621 tcacggatca gctgattgat atattcttct accagttttt cttcttctgt cctcccacca
     7681 ctcaaataat tttgcaaagg ggaagttttt tgtatgtcgg ctaattttcc ccaccatctt
     7741 ctcttgctca agtaaccacc cagcagataa aaaatcagaa agacgccctc aatcaaagct
     7801 aaataagcaa ttgtgctcaa atcaactttg atgtttggcg ccagccacat cacaaagatc
     7861 gtcaatgcaa taaaaaacag ccatcccaag atcaatgtcc actgatcttt caaatattta
     7921 aaaaaattca tcttaaccgc tcatcctttc agggaacgat atatccctgt cctacttttg
     7981 tttcgatata tccttggata cctgcctgtt cgatttttcg gcgtaaccga ttgatgttga
     8041 ctgtcaatgt attgtcatct acaaatcgtt cgtcatccca cagtgctcgc agcaattttt
     8101 cccgacttaa gatctttcca ttgtgcttca tcaaaataaa taatagacga tattcatttt
     8161 tgctcaaatc aatgatctct ccgttgattt ccatacttcc gttgtcaaca ttcaacgtaa
     8221 tgccattgtg gctcatcatt tcactagata attctgtgta gttgtaagaa cggcgaagta
     8281 atgcattgat ttttgcaatc agtacatcga tttggaaatg ttttgtcaca aaatcatctg
     8341 cccccatgtt catagccatg atcatatcca tattcgtatt cctgctggag ataaaaatga
     8401 tcggtacttt cgatacttca cgtatttttt gacaccaata atagccatcc aaaacgggaa
     8461 gattaatatc tagtaataca agctgtggtt cttctctttc aaagtctgag aacacttgat
     8521 tgaaatcggt cgttccaaag gtttcaaatt gccatttctc aagttcctcc atgatcaatt
     8581 gtcgaatgat ctcttcgtct tcgactacca tgatttttgc cataaaaaat ccctccatct
     8641 ttcttcttgc tactacaata tcaaagaagc ccttgtgaaa caagttggct tacctggaaa
     8701 atgtcatttt agcaaacgtt aaaaaaaact ggaaatatgc gatttaatcg cgtttgtctc
     8761 ttccaagcag cttaaattta ttatgttatt cttaataatt ggtctattat ctgttatttt
     8821 tctttcgttg tttttgtctt ttaaattttc gataacacca ataaccgaaa agcgttagca
     8881 ctagcaatat acctagaagg agtataagta atcgataaag atggtatttt tttgtctgtt
     8941 ctatctttga agagacttct tctgtaaagg gaactcgtct tcctgtcact agtaatcggt
     9001 gagtgttcac ggtgtaaggt gtacaagtga taagtgtgac tagatcctgc ttttctctaa
     9061 ttgctaatgt atttgttttt gttggaagga caacaatttt ctcaacgact tcataagcga
     9121 gcatccgacc atacacttca agatagaatc ggtcatcttg ctccatttct tcaagatccg
     9181 taaagagttt tttctcagca ataccgctat gggcggtaat cacggaatgt gtactctctc
     9241 ctccagttgg aaaagaggtg ccttgcagga ctgtcgctcc tctatctaac aaaagatcat
     9301 tcgtttcatc aaataaaggc aagctaacat tgattttcgg aatatagatg gctccgatca
     9361 tatgttgttc gtaatattct tttcctggat tttggacatt tctaaccgct tgctcaaaag
     9421 gatctttgac ttgtcccatt cctgggatta ctgatgtatg agcaagcgtc tgatttttct
     9481 tttcatgcac tgctaattgt tgctcatgtt tttcttcttt atcgcgttca agctgctttt
     9541 gataattctc gatccttctt tgatccaaat aattgctgag agcatctgct aaaaatggat
     9601 atgtaaaaac tgcagctccg gcaagaaaca tcactgccat aaataattgt aataaaagac
     9661 tgatttgggt ttgaggtcta ttacctattt tctttttcat tttcttcacc ttcttattta
     9721 aaaaaactgc agcaaccttt ataaaaccga ttgctgcagc ttatttttgt tgcttatact
     9781 tcagacttca ttttagattt acggtaccag ctgtacgctc caatcatcaa acttattccg
     9841 attagtaaga atgccaagag cccgttccca ccagtagcag gaagtgaccc gcgtttcata
     9901 ttcggtactc tttctggccc tggattttct actcctacga tctgaatttc ttcattatag
     9961 cttccataag agatgataaa ttcagtaaag gctgcctcac ctgttggaag tacataacct
    10021 tctggcgcca tggtctcttt catttgatag gttccataat ctaacccttg aacctcaaag
    10081 tatccatttc catctgcgac aaattctgtt gcttgtccgc ttgttgccca ctcaattcta
    10141 tctgctcctg attcataaac agctaaaggc gactcccctt tataaaatat tgcgtattca
    10201 gaacggtctt cattccacaa ttcgaatctt gcatctttaa gcaattcact gcttgatgca
    10261 tcatattttt caaactttct tccacctgtt gtgactttct ctggcggctc tactccttct
    10321 tcataatcaa attcatcatt tcgtccgatt tcaataaccg ctgtgttgtt atggaaatca
    10381 tccgcttcta gttctgtgga aaccttcaaa ttatacgtga tcgttaaatc tcctccacgt
    10441 gcatctgcta atctacctaa agtatctact ttggctactc cattttcttc tgtcaaaatc
    10501 gtcacgacaa acccgttgct tactacttct actatataat cttgtccttt tgttaaaatc
    10561 gtctcgccgg ctcgcacttc tatttcctga tcataataag ttagaccaac tgtaggcgta
    10621 tctgtgattt tgtaattttt gataacagcg cttccgtttt caaggacaga atcgatgaaa
    10681 taaggaatag gtgctgtgat cgtgtaagaa gccgtttttc ctctttctag atcaatataa
    10741 gaaatcgttt cttgttctcc agcttcatta ataatcgtta cttgtctaag gtcgctttcc
    10801 tctacattca tctgtttatc tgcttctctg atttcgtttt tcggatacaa atgcacatct
    10861 gtattgtatg tgtctttcca tgtagaacca tcccacacgc catccaccat atcaggcatc
    10921 atcactggca tcataacaac cattggagac gcgattctgg aaatatgagc tggcgaataa
    10981 gtttctaaga aaagatagac tttatctcta gaagaaggtg cttcttccgt cacttggacg
    11041 gtagagaata ccgcttctcc agcttcattc gttgtttgtt tgtcaatact tgtcagtcga
    11101 tattttaaaa accaactttc tgtgtgccgt ttttgaatcc attcaatcgc ttcggcagaa
    11161 ttaagaccgt cttctcgttc cggtgttaaa ggattatctc gaatcaaatc gtaatatact
    11221 tccgttacgt caaacaaatc aaaatcgact cctggaatat tttcttcacc aaaatccgta
    11281 gaaaccaatc cgctattcgg tcgttcttcc ggaacagatg agaaaccttt tttgtgtaat
    11341 gtaatcgtca cttcacttgg tttttgtgcg acttcttcgg ctttgactag ttttccgttc
    11401 ccgaaaatcc ctattcccgc agtaacgagt aacagtacac tcattcccgt gacaatcatt
    11461 tttttattca tttttttctc cccgttcttt ttttattaat aaaacagcac ctaacaataa
    11521 aagaattcct agtaaagaaa tcaacgttct tgcttcattc gtttgcggga atacggacca
    11581 ttttcctgat tgacctggat tgcttggacc actcggctct ttcggtttgt ccgttgtttc
    11641 ttttacggtc tcgttataaa cacgtggtgt tgcggattca taggcagaga ctggaacttt
    11701 cccggattct aattcagcca tctcctgtcc gttaactact acatattgtg gttggccttt
    11761 tgcatccacc caaaattcag ggatgatgac ctcgattctc ttacttgctt catccatctc
    11821 gtaaccttcc acacctttta attcttcaaa ataataggtg ccagaaggca agaaacgttg
    11881 tcctgtcgta acaaggccct ctttatccga aatgaatttg cttacatttt tgtcattcaa
    11941 aggatcattg tctgctggtt tgatccattg atttttcaag tcattagcag gagccatatc
    12001 taaataatat ttcccccctt ctatcatctg atatagagca aaaacagcac cttctaatgg
    12061 ttttcctttt tcagttgttc ctctttgacg tccatacttg aagaagtatg gatctcttag
    12121 ataaccgaca tttttaggat agatatgaat ctcttgcagt tcctcggttg attctgtcgg
    12181 gtgataaatt ggcaaaatag cagcaattgg gatagctgtc tgatcgatat caacatccaa
    12241 tccaacttct ggatcaatcg attcttcgaa aatcaaataa actgcatccc gatcttggtt
    12301 tttcttaggt gctttgatac gtgcaatccc gtctcctaat ccgccaaccg tatctttccc
    12361 agttgttacc gaagtcccta tttggacaag cctttcttct gtgattagct gacggatatt
    12421 gtttctgttc gtttcagcga tttgctggac gaattcttta ggagtcatgt tttcagcagc
    12481 ttttttttca tgataataat cggtcatgtc gtaaatggca aatgtcgctc catttagtgg
    12541 caccgtctgt gaaatgatat ctgctgtttc ccctgcttcc tcagagatag ccaagccatc
    12601 attttcatgg tattcaaatt gatcgttata atcgatatct cgaatcatcc gtttatgcaa
    12661 cacgaattcc acgacatctt cccctgattc ttctgccgac atcgcatgtg gaagaaggac
    12721 tgctgcaagc ggtagtaaaa caagtaattg aagcatcaaa cacaacagct ttttcattac
    12781 cttgctccct cctttttaga ttgtctgaca aacaaaccat aggctgctcc tgcaagcgcc
    12841 atgaagaatg cagcaagcag gatatagaat aatcgtccgg atcctcctgt agcaggcaac
    12901 ggattttcag gatcgttccc gacactaagc tgtaatctga ttcgatttgt ctccaaaagt
    12961 tcatattcta actcttgctg tagatcaggc gtctctgctt cttcgtttgg ataatacgaa
    13021 atctcaactt ttagtgtacc cgcttctttt cctggaacta cccgatcatt ttctatgtca
    13081 ggttcttctc gataactaat ttctaaaata aagtaacctg gaagttttct atagctgtca
    13141 ggtgacttca cttccttgat ccgatagacc ccttccaaca agtctgaagc attgaatagg
    13201 gaagaatcgt ttggatctgg tgccaagcct ccctcgatga tttcatactc tcctgcacta
    13261 ttttgtttct caattgaaaa ttctgcgcct tcaagacgtc ggctattcat actgtcaatt
    13321 ttcaaaagtt ccaaatcgat tggcgctagt tcatcttcta aggttacttg tagtacacca
    13381 tcgatgattt catagccttc cggcaaggga gcagtttcgt cttcgatgac cgtatcttca
    13441 atgataaact taccttcttc attcagtgca aactggaaca cttgatcaga tagccgatac
    13501 ccatttggtg cgacagattc cgagacctca tattcaccaa tagacagatg cagaggttgg
    13561 tcgtaattta aatcgacata cttttctact cctacggcac gagaatagaa gtatccgatc
    13621 ccaggcaaac gtttcgattc ttctggttct aacggattac cagtgtatgc tcgatacagc
    13681 gggaaggaag aatcccccac tttcctgata tcgaaacctg caccatctaa tgtatggcct
    13741 tcatggtcta attttctaac tcggatctcc cgataatcaa acgtattgta agcagtgaat
    13801 gctacccata aacgatcctc ttcatctgtt gtatacgtga gatattgcca attttcttca
    13861 cctgtttgct tgagttggat agtccctata gcattatcgt aaagtcgcaa gatccatgtg
    13921 tcattttcat caggttcttt gaaaccttct gggttctggc tctcaatgat tttgtattct
    13981 gcatagttgg tagtttcttc actatcctta taaacaaatg aatctggctc tccgattgga
    14041 tgaataactt tctcaccatc cacgattaca tatttcccgt cttcatctac tgaatagaac
    14101 gtgagtctcc ctttctcttc ctctacttcg ttcacaccag aaagcccttt cgctactgga
    14161 tatccgattt ccagtccgtt accatctgtt tcataaagtt caaactctgc gccattgatt
    14221 ggcatattac tgccttcaat tagtttattg atattcatgt ggattggctt gaattcattt
    14281 cgcatttcca gtttgacata caactcatca tactctgtgc cttctatgtt aggctcttgt
    14341 acaacagaaa gcttgtgata ttctccttca taataggaat tcggatcttt accttccggt
    14401 ccgccgactc tcgaaccaga tgtatattca tctacaagct cgtagtgacc taacatctca
    14461 tcttcgttgg ctgcatattt tttgatttgg aattgatacg tctcatctac taactgataa
    14521 cgtggtggtc cagcgatctc tctgatccaa aatatgtcgc tgactgctcc agtttcatct
    14581 cctaaaatcg gcatcttcgt ttcaaagatc gctattccgt ccgtggtagt tttacttgtt
    14641 tcgattggtt cggcttcccc actctctgga ttttggtcat ataatgcaaa ttcgactcca
    14701 gccaacggct cgccattttg acccttcttg ctgacttgga aattacggcc tttatgttcg
    14761 taacgaatgg aagaagatgg gaaatacatc cgtccagtag tgatatcatt ctcataatcc
    14821 tccaggttct gaatataggc catattgttc actgtgcaaa aatttccgtc ttgagctccc
    14881 gcatcaagtt ttacttggta cttgatcctg accatttccc cttcacctaa agaaatcgga
    14941 gaaaatttat aagcttggtt ttcccgtccg acatacgttg tcggagtcgc cactacttct
    15001 ggtggggctt gtccatgacg ttcttcatcc catatttctg gctcttggta cttcatgccg
    15061 ttttctcctg gatctagatg gtaaaactga atatctgccg atctgccagc tccaaatggt
    15121 gagacattaa aaccagtttc atcataaagt gtggcttgct ggatcgttct cttgaaggta
    15181 gaagagatat cctccaaggc tgtaacaatg tcattcttgt tgttcgcatt gtaatatcgc
    15241 ggtgttacgc catcttcttc taaatcagca atatttttca atacatttcg tccaatagca
    15301 tctagtcgtt gtctcccgct aacgtttcca tcgattccta aaccaatgga gaagatactt
    15361 ggcgggttct cttgatactt gtttttcagc caatgatgat aagcaactgt gttgatcgca
    15421 gatgactttt cttgcgaagt aggactgcca ttcgtattgt tattagaaga accatcacca
    15481 acccagtgag tcgctttatt atctccttct tttacctctc cataacgata gtgtacattt
    15541 acttcatctt ctggacggtt aaagtcagat gcataggtaa ctggatgagt aaaccctgca
    15601 ttagaagtat tcccagaaaa ctcctcaaaa tttctgaaca aaacgtcatt atcttcagca
    15661 atcttatctt ccatcacagt ccagttgctc caagctccat tagtgctcgt acgataactt
    15721 gactgaatcg gtgcataact gaaggtcggt gtcccatctc ccacaacgat taggattttt
    15781 tctggatttc tattttctcc gccattgtct ttatacaatg tttcatagcc atttttaagc
    15841 cctagtgtaa gcggagttcc tccgattggt gtacgattta atgctgtatt ctcacttccc
    15901 gtcaaacgat tgatatcatt tgtcaatgga aagatgtccg aactgatttg ctcatggtta
    15961 ttgatagctg tactattatg gtaaaaattc accataccga ttcgaatatc cagactcggg
    16021 tcagagagca gatctttact catttcgttt actgcctcaa tcaacgcagc atttttagtt
    16081 tgactattgg tcccagcggt taattcactc atactcgctg acttatctag aacaaaaacg
    16141 atatcgattg gactgatttc ctttttctcg cccccgatga catctagata gacattgtaa
    16201 agggttgttg catcttcagg atgtagatca gatgctgtgc tgcttggcag aacaggttct
    16261 acccattttt tgatgtacgc cccgttataa tccaagtaac tgttttcaaa attccgttca
    16321 tttccccaaa gctgaacggt ttgagctgga acgtttctat cttcttcgcc tgcagttgat
    16381 ccattattag tagcatagtc gtaatttcgc cagttcgctc ccccgtttgt ataatcacta
    16441 tcatcgatca agttctctcc gtcatatggc gagcctttgt ctccttgata gcgttcattg
    16501 ctttgtgtcc aatttcctaa cacttttgta tagtcattcg ttgtaaactt cgggtagcga
    16561 tgctgttcgt tttcaacttc tccgctagga tagatatatt cataggggtc ttgcgtagct
    16621 gttggcccaa gacgctccaa aataccgttg aataactggc gttgaatgcg ctggagtgct
    16681 tgaccgctgg gtacgattgg ttcgtccagc ttttccatct cattttcttc gctacgttga
    16741 atttcagcgg aatcttctgt atcagtttca ttttcttgta attcttggtt atctattctt
    16801 tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat cttttctgtt
    16861 tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac ataccattct
    16921 tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga ggatagacct
    16981 gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat tgctaaacgt
    17041 attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc aagggtttct
    17101 tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa tacctcatcc
    17161 tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata gactgactgg
    17221 aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa ttttaaccct
    17281 ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaaca
//
LOCUS       DADQCX010000062        17240 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.062, whole genome shotgun sequence.
ACCESSION   DADQCX010000062 DADQCX010000000
VERSION     DADQCX010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.062"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(105..1124)
                     /locus_tag="J8R83_001868"
     CDS             complement(105..1124)
                     /locus_tag="J8R83_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9574998.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1146..2153)
                     /locus_tag="J8R83_001869"
     CDS             complement(1146..2153)
                     /locus_tag="J8R83_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAZ9574999.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2146..2811)
                     /gene="pgmB"
                     /locus_tag="J8R83_001870"
     CDS             complement(2146..2811)
                     /gene="pgmB"
                     /locus_tag="J8R83_001870"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAZ9575000.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2804..5098)
                     /locus_tag="J8R83_001871"
     CDS             complement(2804..5098)
                     /locus_tag="J8R83_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAZ9575001.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5358..7523
                     /locus_tag="J8R83_001872"
     CDS             5358..7523
                     /locus_tag="J8R83_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9575002.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7827..8660
                     /locus_tag="J8R83_001873"
     CDS             7827..8660
                     /locus_tag="J8R83_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAZ9575003.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8762..10462)
                     /locus_tag="J8R83_001874"
     CDS             complement(8762..10462)
                     /locus_tag="J8R83_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575004.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10969..12129
                     /locus_tag="J8R83_001875"
     CDS             10969..12129
                     /locus_tag="J8R83_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9575005.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12145..12588
                     /locus_tag="J8R83_001876"
     CDS             12145..12588
                     /locus_tag="J8R83_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575006.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13071..13601)
                     /locus_tag="J8R83_001877"
     CDS             complement(13071..13601)
                     /locus_tag="J8R83_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAZ9575007.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13706..14257
                     /locus_tag="J8R83_001878"
     CDS             13706..14257
                     /locus_tag="J8R83_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9575008.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14410..14883)
                     /locus_tag="J8R83_001879"
     CDS             complement(14410..14883)
                     /locus_tag="J8R83_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9575009.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15021..16493
                     /locus_tag="J8R83_001880"
     CDS             15021..16493
                     /locus_tag="J8R83_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9575010.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16490..17200
                     /locus_tag="J8R83_001881"
     CDS             16490..17200
                     /locus_tag="J8R83_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAZ9575011.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5357 a         3101 c         3544 g         5238 t
ORIGIN      
        1 cacgctcttt tttacagata aacaatgtgt tagaagtagt atcttctttt acataaaaag
       61 ctgaccatag gataaatggt cagcgtattt agtgagtcag ctatttagta tgggttttct
      121 aaaggaacga ctgtctctct tttgatcaag cgatgaggga tgaccaaacg tacgccactg
      181 ctcaattctt catggatcaa ttcgcgcagc ttttgcatag cgacacgtcc taattcggag
      241 atatcgatat cgatacttgt aaggtaaggg tgtgttaatg ttgagaagat cgagttgttg
      301 aagctaatga cggagagtgt ctctggaatg acatagccat acatttgcgc caactgcatc
      361 gtgcgaaggg cgaagatatc gtcaatgacc accaatgctg tggcttcgtt ttctttcaac
      421 gttttctcaa aggacagata atcctccgga tgctctagta ctacactgga taacgcagga
      481 agaccagcca tcatcattgc tttttgataa ccgaaatatc gttcgaaata caaactttca
      541 tgagtcgtgt ttgtcacaaa caggatattc ttatgtccat tctggatcaa aaattctgtt
      601 gcttgtttac ctagaagctg gttatcatta tctacataaa cgatttcgtt ctcatgatga
      661 taaggctgtc cgatcaaagt gaaagggatg tggttttggt ataaataatc aatgacagta
      721 tcttgactat ctgaatacac tagaataaaa ccatctactt gtttttgtaa atgcatacgc
      781 tggacgttct ctaacagcaa ttcaaaattt ttagcagtag cgattgctgt agtcatatca
      841 taattccgcg cttcttcgtt gattgcttcc atgatctcaa gataaaatgg gttaccgatc
      901 cgctcttttg aatcaagagg gggtaagatt acgccgatgg cactggaaat gcgttttcct
      961 agattgcggg cagtcatgtt aggaacataa cctagttcat ccataatttt tcggactttc
     1021 ttctttgttg tctcggaaat actaggatga tcgttgatga cacgagagac ggtcgaggtg
     1081 gcaacaccgg cttttttcgc cacatctttt acggtaatag ccatgataaa aacacctttc
     1141 tcttgttatt gtgcagagaa ccgataaatc gtctgactga tccgttcttg accaggatgg
     1201 aggttgatcg atccaaattt ggggaaatga acgatatcag ggatttcttg cggttcgatt
     1261 gctaatccgt agtttgaatg catctgtttt ccattgacag agaaatcagc ttcgaatcca
     1321 gtcgtagaaa ataataccat acttttatta gaagttgcta tagtcatttg gcgaccagaa
     1381 tgcttctcga ataattgtaa ggaagttttg gaaagcctag gatgatgcaa aagaaataca
     1441 tcatctagtc catctggata acatgcaagg atctcttgca gtgttgggga ttttctaaag
     1501 tcgattggca gtttttcttt ttttgtccaa tttccagtag gcagtttttc ttgatctaat
     1561 tcaagcacac catctaaaaa gaccgttaac tgatgttcat agatgtctct tgttccattt
     1621 cctgaaaggt tgaagtaggc atggttggtc ggattgcaga tggtttcaac aaggctacta
     1681 gcagaggttg tcatctctaa ttcgtttttt gttaaacggt aagtgatcgt agcagtgatt
     1741 ggtcctggat aggtagaaaa ttcatctttt aagtaaaaga ccacacctat tgatgatgga
     1801 gttttgaaaa cttctacttc ccaaaattgg aaagaccagc ctttcgtgcc accgtggata
     1861 tggtgtgatc cgcagttttt ctccaatcta tgctcacccc aagaagcatc ccggatcctt
     1921 ccggctacag gtccgacagt tgctccaaaa aagcttttgt ctgttagaac atcttcgaaa
     1981 cgatcgtaag acaataaaac attttctgat tttccttctt tgtctggtgc gaagatttgg
     2041 tgcaggcggg caccgtaatt gagaagaacg acttctaagt agtcgttctt caatgtgatt
     2101 ttctttattt cagtctctgg aactggtacg acggagatct ctggattatc catggtcatg
     2161 ccacttttct ttcaagtaat cgatcgtaag aaaagtcgta tcagggacaa gcgggatctc
     2221 ctctccaagg tcttcagcac gtcccacgcc aattggttga gcgccacttg agaggatggc
     2281 ttggataccg gcttgcgcgt cttcgatccc gatacattct tctgctttta gtccgacagc
     2341 ttttgctgca aggaggaaga tatctggcgc aggttttccg tttgttgctt ctgccgggtc
     2401 ggcaatagca tcaaagtaag gtgtaagacc cattttttca agtaggaatg gcccgttttt
     2461 acttgcagaa gcaagagcaa tcttgatttt ttcttctttt aaagaatcca gtaaaggcac
     2521 gaccccgggg aagacatctt ttggttcgat cgtctggatc atctctaaat aataatcgtt
     2581 ttttcttttc gctaattctg caaattcttc ctttgaaaaa gagtgttctt ttccgccata
     2641 agctaaaagc aaagagagtg agtcttctcg gctgacgcct tttagctgtt cgttgaatgt
     2701 gtggtcgatc gtaatgccga tttcctgacc aagctttcgc caagcacgat aatggaattc
     2761 agcagtatcg gtaatgacac cgtctaaatc aaacaatacc cctttaaaca tttgcttcct
     2821 cctttcttag cgttatttct agacgatccg ctaaagaata agactgttca tagacgtaaa
     2881 tttctagagg agaaccttct aataactcga aagtaacttg ttcatctgtg actgagatga
     2941 acaataaacg tccgcgataa ttgatatgga aagaataagc tttccaagtt tttggcagaa
     3001 atggtgcgaa tctcaactga tcatgggcag ttttcatttg agcaaatcct tggacaatcg
     3061 acaaccagct accagtcatg gaagtgatgt gcaagccgtc ttctgtgtcg ttattgtaat
     3121 tatccaaatc caagcgagct gttcgctggt acatttctac agctttgctt tccattccta
     3181 attctgctgc taaaatcgaa tggatacttg gcgaaaggga agactcatgg acagtcattg
     3241 gttcatagaa atcaaagttt ttttgctttt cttcttttgt aaaagtatca ttgaagaaat
     3301 aaatcccctg tagtacatct gcctgcttga tgaagcaaga tctaaggatt ttgtcccaag
     3361 accaatgctg attcagagga agatcgcttg tgggaatatc ggatacaggc atgagatctt
     3421 tatctaagaa tgtgtcatgc tggacaaaga ttcctaattc ttcgtcaact gggaagtaca
     3481 tgttctctgc gatatctttc catttggcta gttcttcttc gctgatagtg atagcagctt
     3541 ctttttgata agttaaataa ttttctcgcg tgtaacgcaa gacccaagct gcgatcgtat
     3601 ttgtatacca attgttattg atattgttct catattcgtt tgggccggtc acaccgtgga
     3661 tcatgtattt atttgctcgt tttgaaaaat ggacacggtc tgcccagaag cgtgcgattt
     3721 ctgctaaaac ttccagtcct tcatttttca aatattccgt atcgccggtg taattcgtat
     3781 aattgtagat tgcataggca atcgcgccat ttcggtgaat ctcctcgaat gtgatttccc
     3841 actcgttatg gcattcgaca ccagtgaagg tgaccatagg ataaagcgcg ccttttaatc
     3901 cttgttgctg agcgttgtgg attgcttgcg gcagttgatt atgccgatat ttcagcagat
     3961 tcttagttac ttcaggtttg gctaaagcaa gataaagagg gacagcatac gcttctgtat
     4021 cccagtaagt ggctccgccg tatttttctc ctgtgaatcc tttggggccg atattcaatc
     4081 gttcatcttc gccgtagtaa gtagagaata gttggaacaa attgaatcga ataccttgtt
     4141 gtgcttcttc gtctccttcg atgaccacat cggcaagctt ccatcgttct gcccaagccg
     4201 ctgtttgctc ttcttttgct tggatataat tgtttgtctg gttcgttaat tctgagacag
     4261 ctttttctgc ttgctgcgct tctggaatat ctctactagt aagaacgata atttcttttt
     4321 ccactgacca tgtctcacct tgagataatt ctgcagacaa gcaaccatgt aatgctaaag
     4381 tatcttcgtg atagtcaggg atgactgatt ttccattaac gaaatggcgc attgctgcag
     4441 taacagtaaa ttgttcaatc ccaaagttgt ttggaatagt tttagtcgtc aaatagccga
     4501 tttcttctat agttccacga tcaatctcat tccaaaaatg ttcatcatag ttgctgtctt
     4561 cgttttgaac atttccatcc aattttgata cgagtttgac tgttccgcta ccttcaagca
     4621 tttctatagt taaatagata taagctgatt cttttttgac aatgctcaga aaacgttcga
     4681 aggaaatgcg tactttatta gtagaagtag tgattgtgaa tgtacgagat aatacaccat
     4741 ttttcatatc taattcccag taaaagtctt ctggttccaa agaagccaag tcgatcagct
     4801 gatcgttgat cgaaatatct atcgcgataa agttcaaggc gttgatcact tttccaaagt
     4861 attctggata accatttttc caccagccga cacgtgtctt atcgggatac cagacacccg
     4921 ccaaataagt accttgatgg tggtcccctg agtaagtttc ttcaaagttc ccgcgcatcc
     4981 ccatataacc gtttccaata cttgttaaag attcttgcag tcgaagattt tttttatcta
     5041 attgtgtcgt gctgattttc catggatcaa tagcaaatag tcgtttgatc tgtttcattt
     5101 ttctcctcct aatgagctgt tttatacgtt cataataaac gcaaccgatt gcacaagtca
     5161 atagacaaaa gaaaatattt catagaaaaa agcttaaaaa aataaatttt taggagaaaa
     5221 ttatagaagg gaacacacgt attataggtt ttatagaatg gtatagacag aaaaataaaa
     5281 aataaagcat ttacaaaaaa gaaaacgcac gctataatac gtttaacgaa accgattgcg
     5341 taaaggagct aaacggaatg aaaaagatat ttagttttga gttttggcaa aaatttggaa
     5401 aggctttaat ggttgtggta gcagttatgc cggcagctgg gttgatgatc agtataggga
     5461 aatcaattcc cttgatcaat cctgattgga cgccgcttgt cacaacgggc ggagtaattg
     5521 aaaatattgg ttgggcaatt attggtaatc ttcatatttt atttgcttta gcaataggag
     5581 gaagttgggc aaaagaaaga gcaggcggag catttgcagc tgggatctca tttattttaa
     5641 tcaatcggat cactggggct atctttggtg tcacaagtga catgcttgcg aatgaagatg
     5701 catttaccca cactctgttc ggtacgaaga tcatggttaa aggatttttt acaagtgtat
     5761 tggaagcacc agctttgaat atgggagtat tcgtagggat catcgctgga tttgtcgggg
     5821 caatggctta taataagtac tataattata gaaaattgcc ggatgctttg tcatttttca
     5881 atggaaagcg ctttgttccg tttgttgtta tcttatggtc aacaatcgtg gcattgattc
     5941 ttgctgtggt gtggccaaac gtacaggctg gaatcaataa ttttggttta tggattgcag
     6001 aatcacaaga aagcgcaccg attctagcac cgtttttatt tggaacatta gaacgtttac
     6061 tattgccatt tggattgcat catatgctga cgattcctat caactataca cagcttggcg
     6121 gatcgtatga gattttatca ggcgcacagg cggggacaca agtatttggg caagatccgt
     6181 tatggttggc ttgggccact gatttagtga atcttaaagg tgcaggggat atgtcgcaat
     6241 atgagtttgt gttgcataac tggacgccgg ctcgtttcaa agtaggacaa atgattggtt
     6301 cttcaggtat cttgatggga atggcttttg cgatgtatcg taatgtcgat cctgataaga
     6361 aagcaagata taaatcaatg tatttttcag cagcgttggc tgtctttcta acaggtgtaa
     6421 cagaaccatt ggagttcatg tttatgtttg ctgctgtgcc attatatgtc atttattcag
     6481 tgatccaagg ggctgcattt gcgatggcag atatcttgcc attgcgggtc cattcatttg
     6541 ggaatatcga attgctgact cggacaccgt tagctatcaa agcgggtcta ggtggagatc
     6601 ttatcaactt cgtgttgtgt gtgatcgctt ttggtgttgt tacgtatttc ttagcaaatt
     6661 tcttgatcaa aaaattcaac tttgctacac cgggacgtaa cggaaattac gacaatgaca
     6721 gtgaagaaac cgttgtatct aacagcggaa caggaacagc agatcagcaa gtggtccaga
     6781 tcattcattt gctgggagga aaagaaaata tcaaagatgt cgatgcttgt atgactcggt
     6841 tacgcgtaag tgtaaatgat cgagaaaaag tagggactga agaagcctgg aaacgagcag
     6901 gggcgatggg attgatcgtc aaagacaatg gagtccaagc agtttatgga ccaaaagcag
     6961 atgtcttgaa atcagatatc gaagatctgc tgcaatcagg agcagagatt ccagagccag
     7021 aaatggtttc tacaggaaat ggacaagcag gtagtaagca atacttaggt atagaacaag
     7081 aactagtttc cgcagcttct ggagaagtga ttcctttatc tgaagtaaaa gatccggtat
     7141 tctcacaaaa aatgatgggt gacggctttg ctgttattcc aacatcaaga gaagttgttg
     7201 cgccgatcgc tggaaaagtg acaagtattt tccctagcaa acatgcaatt gggctggaaa
     7261 cgaaagatgg tatcgaagtt ttgatccata tgggaatcga tacagtccaa atgaatcagc
     7321 cagcttttga gattgctgtc aaagaaggcc aagaagtagg aacaggaacg aaattagctg
     7381 agatggatct tgatgtgatc caaaacgaag aaaaagatcc aacgatcatg atcgtattta
     7441 caaacgataa agtagaagaa gtagtgatca agcaattagg tacagtgaca gctggtaaag
     7501 tgatcggctc cattaaaatg taaggagagg ttgtgaaaaa gctgtcctgc atcaagtcat
     7561 aagaacagcc aaacaaaaat agctcctcct atttttcgtt tggttgggct tattaccgag
     7621 aagcagcagt ttgaatactg tttagtggag aggtcgtgaa aaagctgccc tgcaccaagt
     7681 gataaaaaca gccaaacaaa aaatagctcc tggtccattg agcttattac tgaggagtta
     7741 gcaggagaac actatttgct ggagaggttg tgacaaaaat tttgtcacaa cccttttgtt
     7801 tcgaaatgaa gacaaggaga aaaccaatga aattcatgac actcaacacg catagctggc
     7861 ttgagccaga accagagaaa aaattgcaag aattagcaga taagatcctg ttagaagatt
     7921 atgaagtgat tgctttacaa gaaatcaacc aattactgga atctgaagaa gtagaacctg
     7981 cgaagctaat gaagttctgt ccggtaaaga atcaagtacc tatccgtaaa gataattttg
     8041 cctaccgttt agttcagctt ttaaaggaac acggaaaaga gtatttttgg agttgggaaa
     8101 tgagccacat cggttatgat aaatatgaag aaggaaatgc actgcttacg aaaaaaacat
     8161 tggaaagtca ggtccttacc gtctcccaat ttcaaaagaa agaagattat cagacacgca
     8221 agatcttgat tgggaaaaca aagatagatg atcaggacat ttttgtctcg agctgccact
     8281 tttcttggtg gacagataaa aaaagtggct tttattttga gtggaaaaac ttggaaaact
     8341 actttttgga aactcgcgta ccactttttt tcctaggtga tttcaataat ccagtagact
     8401 ctcaaggtta ttatactgta agagaaagtt gccttcttct tcaagattcg tatgttgtcg
     8461 cgaatgaaaa aggaaaagca gctactgtgg aaaagaaaat agatggttgg gaacaaaata
     8521 cagaaaaatt gcgtatagat tttattttcg tccctgaagg aatgcaggtt aaaaaatatc
     8581 aacggatttt tgatgggatc gatagtccaa tcatcagtga tcactacggg gtggaaatcg
     8641 aattagatgt gaacgaataa aaaatataac atataacata aaaaaactga ttaaaataaa
     8701 actctccaaa cgattatacc gtttggagag ttttttgatc ggatgtattt atcccttttg
     8761 cctaagcacg taaaagcttg tatctatgat aaataaataa acatagcaag gtaaaccagc
     8821 caatcaaagt aagagaaaga atgaaataga aatagattgg cgtttgataa tgaagcgtga
     8881 gctcgttgat tcctttttgc tgcttcacga ttggggtccc gatatctgtt acttcataat
     8941 cagtcaatgt ttttccattt tgctgtagca cagtccgatc gtagacgata acagggatat
     9001 gaacagtttt gtccccagtg tttttccact tgattgtcaa aagaccgcct ggatgtgttt
     9061 ttataaaagt tgtttcgttt tctagtattt cttcgttata ccggtcgtat ttattgtctt
     9121 ttgtctcctt atagattggc agatagtcag gtgtggtttt ttggaaaacg aacaagctgg
     9181 tagacatatc tttgctgaag aatgttttcc ttgcttcttc cggcgtatcg aatagataag
     9241 tatgtcgact gacaaatgtt tcattttccc acttttccag atgctggtat aagttctgga
     9301 tcgtctgtgc tgaaaaaata agaatgccaa atatacttaa aagacggaac cacttttgtt
     9361 cagaccactg gttcagtgaa agggcaaggt aaagtagaag caatagcgta aatggcacga
     9421 aaaatcgaaa tggaaactgg atcaaactaa taaaaggcac atttttttcg atcaatgtcg
     9481 tccatggaat caagctagta gaaagaaaaa agaaaacaag acttgtgtac aacacgattt
     9541 tttggaataa ggtgttcttt tgttgaaaga aaataaaaag caaaaaacct gataatatca
     9601 atataggaaa ggccttaggg taatggagcc aataactgcc atccagatct atcgcctttt
     9661 gactcatttc tctgttaaca aagggaggaa gaatcttatt cccactgtaa acaatagcta
     9721 atcctgccca aatatttgct gtcagaacaa aataaagcaa gaccgactta atcagttgaa
     9781 gcagtgcttt tcctttttca gtctggttaa aaaagtaata aagataaaaa gggatataca
     9841 tcaaagctaa catgatcgaa gacagtaaat ggatctgtgt cataagtccc actgagacag
     9901 cgactttgat aacagggaac tttttatgaa ggacgaaatc agcaataggg atcatacata
     9961 aaggataaaa acaagtcccc cagctagtga atccttggtt gatagaccag tattgaatag
    10021 aatacgtact catgaataaa acggctactg gtacacttac ccaatttcga acattgacat
    10081 atctcagtaa aatcagcata gaaaatcctg aaataagata aagaatgaaa tttgaaagaa
    10141 tctgataatg aaaccagcta cctgcaagca acacgatcaa tccttgtaaa taagcgaaaa
    10201 atgggccgta aacggcattc acgatcctgc cactttgctg gaatccataa agggaaggaa
    10261 aataatggaa atccccatat ttaatttgtt gcgcggcatc atagaaccga ttgtaatgga
    10321 atggggcatc agcacccaaa attagtttat gtgtgaataa atgaggcatg agaaatgcca
    10381 aagcaatgaa aaaaattgct aaaaatgggc catatttttt caattgtcga actcctttgc
    10441 aaactttaga taaattcatc atatatccta tgcgagaggt aggcaagaaa ttagaaaatt
    10501 catgaaaata tttatgaatt ttacaagaaa aacataagtg aaagttctaa ggagagagga
    10561 tgcgacataa gttttgttgc atctccttgt tttgaaacag aatttttctt aatactcgaa
    10621 acaaagtagc tttttcatga cctctcggta aacggtgttc aatcagctgc ttctcggtaa
    10681 taagctcact agcctagaaa atatgagaag ctattttctg actagcgctc ttattactca
    10741 aagcataacg cagttttcac aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg
    10801 gtaataagcc caacccaaca aaaaatatga gtagctattt ttttgggctg tacttattac
    10861 ttgatgcagg acagcttttt cacaacctca tcggctttca ttttctattt ttttcctgaa
    10921 cccatataat aaaagaaaga acaaaaaaac ttgcaaggga ggacacatgt gaagcagagt
    10981 aagcaaaaac agtctcgtcg acttttgttt cgtttgtttt tattaatatg tatcgtcgta
    11041 gggttactga tcgctttata tccattttat gtggattctt taaatagttt tattgatcaa
    11101 aaacgtatcg aacaagtaca aaaacggacc gcagctgaaa ttgaagtgca gcgaaagaaa
    11161 atggaggaga aaaaccaacg attaactgac caaggattca atcctggtac tgatcctttc
    11221 aatgaaaaga acagaaatga aagtacaaca tccagccaat tagaggaatg gctgatcgga
    11281 agtatcaata tacctaagat ccaattaaat atttcacttt atgatcggct caatggtagg
    11341 atccttgaaa atggagcagg cgtcttgcaa ggaacctctt tcccgcttgg tggaaattcg
    11401 acgcattcag tgatctctgc tcacagcggt ttacctaatc gacggttatt taccgaatta
    11461 gatcgtttag aaaacggaga cacgtttatt ttgactgttt tgggggagaa attggcttat
    11521 caagttaaaa atatacaagt ggtactgcca gatgacacgt ctgttctaac gatttcagaa
    11581 ggagaagact tagttacctt gcttacatgt acgccgtata tgatcaacac gcatcgtttg
    11641 ctagtgacag gacatcggat tccttataac gaatcggtaa aaaaagaaga aggaaaagga
    11701 aatcaggaaa gaaccatgcg gcaatggttt attcttgcag gaacgataat agctgtagtc
    11761 atactgttag tgtttatcgg acgactaatc tatcagtata gattaagtaa aaaagtgctt
    11821 gatttttcat ttattattag tgattcgtca gggaaaccgg taaatggtag ttcattcatt
    11881 ttgaaacata agaaaaaaac acttactaga aatggtgtgc cgttttcagt acaaagcgac
    11941 catcatggga aagtcaagct ggatcaattg cctggtggaa cttatcgaat cgtttcagct
    12001 gatgatccta aagttgctgt ttcttttggt attagaaaag taaaacaaga gaagatatac
    12061 ttttttgagg ggcgaaaact tgtaaaagag cttcaaaaaa atggttttta ttttaaaatc
    12121 aatgaataag taaggagaga aaaaatgatc cgcacaacaa caaaattgtc tgccaaagaa
    12181 ctggaatctg ttctatcgat ttggctgcat gctaacttgg attctcatga attcattcca
    12241 tcaacttatt gggagaatca agtagaatct gttaggaaag ctttaccaga tgcagtgatt
    12301 tacttagcag aaatagatca agaaattatt ggttttgctg gggtgattga tcagtttatc
    12361 gcaggaatct ttgtgaaaag ggaataccgg caacaaagaa tcggtacgca actaatgaaa
    12421 aaaataaaag aaaccaataa aacactgact ttgacagtct atcaaaaaaa tcaatcagct
    12481 attcatttct atctttcaca aggttttaca attcaaacac agcaaaaaga tgaagcagta
    12541 aatgaggagg aacttgtgat gaaatggaat caaaacgctg atttttgatg aacagaataa
    12601 cgaaataatg ctcccagcct aattttttgc tgggagcatt atttcatttt gaagtcacta
    12661 atttaactgt gtgaatatgc agttgttaca atctttgata aacggtgttc aatcagctga
    12721 ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac tatttttcca tttgtttctc
    12781 taatactcag gtcaaaacgc tgatttcaca acctcttgat aaacggtgtt caaacggctg
    12841 cttctcggta ataagcccac tagcctagaa aatatgaaaa gctattttct aactagcgtt
    12901 cttattactc aaagcataac gctgatttca caacctcttg ataaacggtg ttcaatcagc
    12961 tgaccctcgg tattagctca aaaaacggca aaacatgagg aactattttt ccgtttcttt
    13021 ctctaatact caggtcagaa cgctgatttc acaacctctc tttcacaacc ttattttact
    13081 cgtttataat tttcatcgaa gtattttccg ctacggatat catctggcat tccatcgtat
    13141 ggttcttcgc taataacatc ttcattgtct atacctgcat cacccatata agtgatcgta
    13201 gcaaattcag gaacaagtaa ttttggataa gtttcatatt tttcacgagc tgcttccatt
    13261 tctgcgatat gttcgttttg gaaagtaaca gtgatttctg gatgttcttc aacccattta
    13321 gggaaaaaga tcattccgtg aagtttcttt tcatttggca taaagtccaa tgccacgtct
    13381 gtccctgttg gctctgtcca agtgattttg aatacgccgt ccgtcaattt aacgatatca
    13441 gcttcttggt cttttaccca acggcctttg accattccgc catggatacg gtaatcaaca
    13501 gtatggtcat ttttggcata ccattcatat tcccaaccat tgtcatacgt atagataaag
    13561 tgagttccaa taaaatcttc caattcttta aattctttca tgtttaagca tctccttata
    13621 aattaaaaca tgtaataaac tacatgtttt cgattactca tttatgatag aatggattta
    13681 aagatttgtc aaggagggaa aactgatggc aagaaaaaat acacttcgat atattttgtt
    13741 agggttatta agtaagaaga agatgacagg atatgaattg aatcaatcgt tcaaaaatga
    13801 aataggagaa ttttggcaag caaaacatag tcagatttat cctgaacttg caaaaatgga
    13861 agagcaagga atcattcagc atcaagtaga gatcacaggt gaaaaattgg aaaagaaagt
    13921 ttatgaatta acagaagaag ggaaggaaca attggcagag tggattcata cacccaccaa
    13981 tgaactaccg gttaatcgag acgaatttgt tctgaaattg tatttcgtca aagacgtgaa
    14041 tgatccggca ttagtagaaa ttattcagca gcagcgtgac cttcatgaag aaaaacgact
    14101 tcatctatta gagcgaaaaa aaacgatctt tcctactgaa aaagaaaaac atgaaaatta
    14161 cggacactac ctgattttag cgcatgcgat caatcgggaa acagaatatg caaattggct
    14221 aacagatgta ttagaagaaa gtaaccgaaa aaaataaaaa aatatccgaa cagtgatgga
    14281 gaattccttt ctatatgaaa gaaacgcaga tcaccgttcg gatattctta tgttcaaaca
    14341 ggcctttttt caagtattta tgtagcatct acttattaaa aagcttggta cttaggagat
    14401 tagtggcgtt tagagttctt ttaacaactg ttcgtagtca gctttttcat cgacaggaag
    14461 gagcttgtaa gttaattcgt ctgtctcgtt gtcatgaatg atgtacatct tagcattctc
    14521 ttctttgaag ttaccgattt gtaaaatcgt atagcgttcg tcgatcaatt cgatatcttt
    14581 gattgctttt gaaaaaactt tacggacatg gtgcattttc ttttggcgga tttctgcctt
    14641 ttctgcagct tttgacaaag taaatccgtc atctaaatat tttttgatca gttctacttt
    14701 tatgactgta ggtaaacgat attttctagg acaattcgca tcagcttcga tcgaacgaat
    14761 gaatcccttt tgttcccaat accttaattg acgtggagac acacctacga tatcacttaa
    14821 ttcactgatg ccaacaacca attgatcatt ttccaacaaa cgtttaaggg aagccccaac
    14881 catttttgtc actccttttg tcctcttgct tcccttaatt atatccgtat taacttatgt
    14941 gtcaagtagg ttgacaaata gcgaatttag gactaaagta ttctagtagt ttcagaaaaa
    15001 attcagaaag aaggagaaat atgagtaaca accaacccgt agatatttac ggaaaaccat
    15061 ataatcggac acttttagtt gttgtcttat taattggtac attttgtacc gttttgaatc
    15121 agaccttatt gacgacagct tttcctacat tgatgaaagc tttcgatatt tcagcgtctg
    15181 atgtgcaatg gttaacgact ggtttcttgc tagtcaacgg gatcatgatc ccaataacag
    15241 catggctgat caataaattc agttcaagaa atttatatct ttctgccatg acgatctttt
    15301 tgatcggaac gattacttgc tttacagcac ctaattttag tacattacta atcggtcgtt
    15361 tgatccaagc ttgcggtgtg ggagtatcga tgccattatt gcaaaatatc atgctatcta
    15421 ttttcccgcc agaaaaaaga ggatcagcaa tggggatgtc agggatcgtt attggacttg
    15481 ctcctgcttt aggccctaca ttatctggtt atatcattga taactaccat tggcgtgact
    15541 tgtttggtat ggtactgcca atcgttgttc ttgtcttggt tttagcattc ttcctaatga
    15601 aaagtgttat tccattgtca aatcctagca ttgatatttt atccgctatt ttatcaacga
    15661 ttggattcgg tagtttactt tacggatttt ctagtgtagg agatgacggc tggggaagct
    15721 tgaaagtaat tggtttctta gttgttggtg tgattttcat cgccttgttc tcatggcgtc
    15781 aattacattt ggaacatcca ttcttggaac ttcgtgtatt caaatcatct acattcacga
    15841 ttgcagctgt tttagctggt gtaacaaata tggcgatggt aggggcagaa atggtcgtac
    15901 cattgtatat tcaaaatatt cgtggagaat cagcattcca ttctggcttg atgttgttgc
    15961 cgggtgcatt gatcatgggg gctatgatgc ctgtgacggg tgcgattttc gataaatacg
    16021 gcgcgaaacg tttagccatc acagggatgt tcattttgac agcggcaact gcaccatttg
    16081 ctttcttgac aaaaacgact ccagttttat atatcgtgat cctttatgcg atccgtatgt
    16141 ttgggatctc catggtcatg atgccggtaa cgacttctgg tatgaatgca ttgccaaata
    16201 acttgatcag tcatgggaca gcggtaaata atacattccg tcaaatcgca agctcgattg
    16261 gtacagctat tttgatcagt gtgttgacga atgtgacaaa agcaaatatc ccaagcaaat
    16321 ctgtattgga taatacgcca ttagcttata aagatcaggc aatcaatgcc acactgtcag
    16381 gttaccatgc cgcgtttatc gtagcgatca tctttgggat tcttggcttt attattgcct
    16441 ttttattgaa gaaaaaagaa cctgttctaa tgaaagcggg ggataatgca tgattattgg
    16501 agttttgatt gtcagcttgc ttgcttttgc tttaacgaac gtgttcgcta aaaaaacatg
    16561 gcaaaccttt ttatctttga ttttcggact aatcttcgtc gcttcactaa gtttgatcgt
    16621 cgctaatttg tccaatcact ttggaatgga aaaagtaacg gaaacaaaaa cagaaaaaat
    16681 tgtttccagt gctgattccc aaggagcaga tatgcttttg tataaagctt tagggaatgg
    16741 aaaagaaaaa gtgtatcttt accgaacaaa tgaaaaacaa gaaaaaccaa aagcaactgg
    16801 tacggataac gaaacaaata aagtagaaaa gacagacggc gatgctgaaa aagtgacgaa
    16861 aactacttat tgggaataca aaaacgacat gtataaattc tggttcaata ttgctgataa
    16921 caatcacgaa tatgacagcc gagtgaatac attcaaaatc ccagagacat gggtagaatt
    16981 aagtacggac caagcagcca agttagctga attagtgaag aaacagcaaa gtacgatgga
    17041 aagtgaagca aaagcttatg ttcaagacgg tatggtaaaa gcaatgactg aaaatccaaa
    17101 aatgagcaaa gcagagcaag aacaacgtac gaaagcctta gctgctgaat tccaacaaca
    17161 agcattcgca aaattagtga aagaagcaaa aggcgaataa tattttgaac accatgtagg
    17221 aggttgtgaa aaagctgctc
//
LOCUS       DADQCX010000063        17018 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.063, whole genome shotgun sequence.
ACCESSION   DADQCX010000063 DADQCX010000000
VERSION     DADQCX010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.063"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2435)
                     /gene="parC"
                     /locus_tag="J8R83_001882"
     CDS             complement(<1..2435)
                     /gene="parC"
                     /locus_tag="J8R83_001882"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAZ9575012.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPE"
     gene            complement(2447..4492)
                     /gene="parE"
                     /locus_tag="J8R83_001883"
     CDS             complement(2447..4492)
                     /gene="parE"
                     /locus_tag="J8R83_001883"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAZ9575013.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(4658..5092)
                     /locus_tag="J8R83_001884"
     CDS             complement(4658..5092)
                     /locus_tag="J8R83_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAZ9575014.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5219..5857
                     /gene="plsY"
                     /locus_tag="J8R83_001885"
     CDS             5219..5857
                     /gene="plsY"
                     /locus_tag="J8R83_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAZ9575015.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(5989..6864)
                     /locus_tag="J8R83_001886"
     CDS             complement(5989..6864)
                     /locus_tag="J8R83_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAZ9575016.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(6946..7737)
                     /gene="codY"
                     /locus_tag="J8R83_001887"
     CDS             complement(6946..7737)
                     /gene="codY"
                     /locus_tag="J8R83_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAZ9575017.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(7755..9155)
                     /gene="hslU"
                     /locus_tag="J8R83_001888"
     CDS             complement(7755..9155)
                     /gene="hslU"
                     /locus_tag="J8R83_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAZ9575018.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(9169..9717)
                     /gene="hslV"
                     /locus_tag="J8R83_001889"
     CDS             complement(9169..9717)
                     /gene="hslV"
                     /locus_tag="J8R83_001889"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAZ9575019.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(9754..10659)
                     /gene="xerC"
                     /locus_tag="J8R83_001890"
     CDS             complement(9754..10659)
                     /gene="xerC"
                     /locus_tag="J8R83_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAZ9575020.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(10857..12233)
                     /gene="trmFO"
                     /locus_tag="J8R83_001891"
     CDS             complement(10857..12233)
                     /gene="trmFO"
                     /locus_tag="J8R83_001891"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAZ9575021.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(12202..14280)
                     /gene="topA"
                     /locus_tag="J8R83_001892"
     CDS             complement(12202..14280)
                     /gene="topA"
                     /locus_tag="J8R83_001892"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAZ9575022.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(14402..15259)
                     /gene="dprA"
                     /locus_tag="J8R83_001893"
     CDS             complement(14402..15259)
                     /gene="dprA"
                     /locus_tag="J8R83_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAZ9575023.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(15315..16082)
                     /locus_tag="J8R83_001894"
     CDS             complement(15315..16082)
                     /locus_tag="J8R83_001894"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAZ9575024.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(16075..16935)
                     /gene="ylqF"
                     /locus_tag="J8R83_001895"
     CDS             complement(16075..16935)
                     /gene="ylqF"
                     /locus_tag="J8R83_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAZ9575025.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT         4330 a         3801 c         2959 g         5928 t
ORIGIN      
        1 atctcaggag catcgataac ttcgatgact tctccacctt ttttctcatc catcgcaaat
       61 gatccattcg atgttcgatc acctataggg aaatcagttg ggtcaatcgt taactgctgc
      121 cctttttgat tcatcaaggt tatttctttt gatcttcctt ccgacatata gataatacgg
      181 tgcggatttt ttttcagctc acgcatgacc gtcactcccc gcttcgcacg tgaagtttgg
      241 ctgatttctt gagcaagcat gcgtttaaca gctcctcgct gagtaacgat tacgatcggc
      301 gtatcacctt ctgctaacac aagcagcccg ttgataatcc tatctccatc tttcaaattc
      361 atagacttca ctccagctgc ctttgctcca acaacgggaa catctgttaa aggatagcgc
      421 aaacccattc cttgatgcgt tactaagaaa acatctaagc ctggctgatc ttctttcaga
      481 tacacagcaa tcagttcatc ttcttccgcc tttagcttca tacagctgag cggacggctc
      541 ttataggtgc gccatggttc gaactctgtc attcgtgttt gcttgatcaa tccattcttg
      601 ctgatgaata caaatgtttt ctctgcttga attttttgat atgggaaaac agctaaaatc
      661 gattcgtcta cagacagatt ggagattgtt tgagaaatgt gctcaccagc atctttccat
      721 ttcaaatcgg gtagttcatg gacagggcgg tagatcacat ttgctttatt tgtgatcaga
      781 agaacatggt ccaatgtact caattcacct gagtatagca agtagtcgcc ttctcgcatc
      841 ccgatttctt ctggtttgga agcactataa gaacgaaggc ttgttcgctt cacatagcct
      901 tctcgcgtca cactgacaat tacgtcttct tgtgccacta agacttgcgt atcaattttg
      961 atttcttcga tttcgtcttc gattgtcgtt agacgagcgg aagaataatt ttttttcact
     1021 tctcgcaatt cttttttcat aacagagaaa agctctttgt catttgaaag gattttattc
     1081 aactctgtga tttgcgcaat caagctttcg gattcctttt gaagctctgt gatatccgtg
     1141 ttcgtcaaac ggtataattg caatgtgaca attgcttctg cttgttcttc tgtaaattga
     1201 aagacgtcga ctaaattctt tttggcgtct tttttgtctt tactttcacg aatcgttgcg
     1261 attacttcat ccagaatcga taaagctttc atcaatcctt ctacgatatg ctgtcttttt
     1321 tgagctttgg ctaaatcgaa ttgactacgt tttgttatga cttgctttcg atgctcgata
     1381 taacttctta aaatgtcttt cagtccaact tgatgcggag tcatatggtc gatagcgacc
     1441 atattgaaat tgtaattgat ctgtagctca gtgtttttga acaaataatt caaaattcct
     1501 tgagcattgg cgtctttttt caattcgacg acaatttgca gacctgttct atcactttca
     1561 tctcgtactt cagctattcc atcgattttc ttattcaaac ggatctcatc catttttttc
     1621 accaaggtcg ctttatttac ttcatatggg atttctgtga tcacgatttg ctgtttatta
     1681 cccttcattg cctctatctt tgttttcgaa cgaagaataa cttttcctcg tcctgtttca
     1741 taagcttttt tgatttcatc ttttccttgc aagatccctc ctgttggaaa gtcaggtcca
     1801 ggaatatatt ccatcaattt ttcaaggctc gcttgtggat gatcgatcat atagattgtg
     1861 ccatcgatca cttcagctaa gttatgagtc gggatttctg ttgcatatcc agcagatata
     1921 cctgtcgatc cattgacgag aaggtttggg tatcgagctg gaaggactgt tggttctttt
     1981 tctgtatcat caaaattcca cacgagatcg actgtttctt tctcgatatc tgctagcatc
     2041 tctccactta acttggataa tctggcttca gtataacgca tcgcagcagg tggatcaccg
     2101 tccatactcc cgttattccc gtgcatttcg atcagtactt cccgcaactt ccagtcttgg
     2161 ctcatgcgga ccatcgcttc ataaatactg atgtcaccat gaggatgata attccccatg
     2221 atatttccga cagattttgc tgatttacgg aatcctttgt catacgtatt gccatctttg
     2281 ttcatggcaa ataatatccg gcgttgcact ggcttcaatc catcacggat atcaggcagt
     2341 gcacgttctt ggataatata tttggaataa cgtccgaagc ggtcacccat cacttcttct
     2401 aaagttaatt cttgtacttc ttgtcgattt tccatcaggt gacctcctat tctacttcaa
     2461 ataactgatt gttttcattt ttatctgctc gttcttcatc taataaatca ttagaaactg
     2521 aaggagagat ttcagtatcc tcttttttat ctaagatact gccatcttct tcgagcgtaa
     2581 attgcacgtg attttcgatc cattttcttc gaggttctac tttgtcaccc atcagtgtgg
     2641 ttactcgacg ttcagcttgc gcagcatcat cgatacggac gcggatcaac gtacgggaag
     2701 tcggatccat cgttgtttcc cacaattgtt ccgcattcat ctctccaagt cctttatatc
     2761 gctgcagcat atatcctttg ccgacttttt taatcattgc tgccaattcg tcatctgtcc
     2821 acgcatattc aatgacttgc ttctttcctt gtcctttgga tactttatat aaaggcggta
     2881 acgcgatata tactttccca gcttcaatca gcggtttcat ataacgataa aagaaagtaa
     2941 gcagtaatac ttgaatatgg gcgccgtctg tatccgcatc ggtcatgatg attactttgt
     3001 cgtaattaca gtcttcgata gaaaactcag gaccgactcc tgcaccaatc gtatagatca
     3061 tcgtattgat ttcttcattt ttcaagatat cttgcatttt agctttttcg gtattgatga
     3121 cttttcctcg taaaggtaga attgcttgga actttctgtc tcttccttgt ttagcagatc
     3181 cgccagcaga atccccttcg actaaataca attcattttt cttagggttt cgggattgtg
     3241 cgggtgtcaa ttttcctgaa agaagagatt cgcctttttt acgcttcttc ccatttcggc
     3301 tttcttctct ggctttacgt gctgcttctc tcgcttctct ggctttgatt gctttacgga
     3361 ccaacatctg gctcatttcg ctattttcct gcaaataaaa gcccatttgt tcactgatga
     3421 cgttatctac tacggtacga gcaactggcg taccaagttt ttcttttgtt tgcccttcaa
     3481 attgcagaag attttcaggt acacggatag aaagtacagc agctaaccct tctctgaaat
     3541 cactaccttc cagattcttg tcccgttctt tcagcaaacc aacttttctc gcatattcat
     3601 tataagattt cgtcatcgcc gctttcatac cagcttcatg ggttccccca tcttttgtcc
     3661 gaacgttatt gacaaaagat aaaacatttt ctgaataacc gtcattgtat tgataagcga
     3721 cctctacttc gataccttct ttttctcctg aaaaataaac aactggtgtc aatgtatctt
     3781 tttcttcatt cagataatca acaaattctt tgattccttc ttcgtaatga aaaatttcct
     3841 tgactggttc ttctccacga agatcagaaa gagagatttt aacgcctttt agaagaaagg
     3901 cagattctct taaccgttcg gctaaaattt catatgaaaa tttcgttgta ctgaatattg
     3961 tatcatctgg taaaaaatgg acagtcgtcc cgtttgcttt ttttgttttt cctatctttt
     4021 tcaaagtacc gtcaggttta ccgccgtttt taaatttctg ctgatactct acgccatctc
     4081 taacgatcgt tacaattagc catttcgata aggcatttac cacactggct cctacaccgt
     4141 gcagtccacc agaagttttg taccctcctt gaccaaactt tccgccagca tgcagcacag
     4201 taaaaatcac ttcaactgtt ggtattccgg aagcatgcat tcctacaggc atcccacgtc
     4261 cgctatctgc aacagttata ctattgtctt catggatggt cacatcaatc tcactgccat
     4321 aacctgataa tgcttcgtca actgcattat cgacgatttc atagactaaa tgatgcaagc
     4381 ctcggctgtc agtggatcca atgtacatcc ctggtctttt tctaactgcc tctaatcctt
     4441 ccaatacttg gatggacgag tcattgtatt cgttgtttac tttttttgcc aaggcaaacg
     4501 ctccttcaat aatactttgc ggcaaaaccg caccacgatt atcatactag aaaaggtcgt
     4561 gaaaaaaaag agggtagacg agaaatcaat tttaattatc tcctaaccgc tttttcgaca
     4621 ttcccctcta tcgatcatct cttctttgtg gtcattttta tttttggttt tctttcaact
     4681 taccaagttc aatcttaata caacgatcca ttacgatatc tgtacgtcct gcttttctta
     4741 gcatctcagc tgcttctttg ttttcaatcc ctaattgtgc ccagaacact ttagcatcag
     4801 ttttcaaaaa atcacctgct atttcaggta aaaattcact ccgtctaaat acatctacga
     4861 tatcgattgg atcatcgatt tctgtcaaat tcgcatagac tttctcgcct agaatttctt
     4921 caccagccaa taatggattt actggtatga ttttatatcc attgtcttgc aatacctgtg
     4981 caaccatgta acttgttcgt tctggtttat tgctcaagcc tacgacggca atattttttg
     5041 cttcttccaa atagttgaaa atcgtttctt gtgttggatt ttttacagac atttctgcca
     5101 ccccttgctt ttctttttat tccatctatt atacttgtat ctttcatttt ttcaattgtt
     5161 cctgttacct attcatgcta aaataaagga tagttttcaa cttgaaagag ggtaaaaaat
     5221 gaaattgatc ttattactta ttttagcata tcttttaggt tctattcctt ccggtgtctg
     5281 gattggcaaa ttgtttttca aaaaagatat ccgacaacac gggagcggta atactggaac
     5341 gaccaataca tttcgtgtat taggcaaaac agccgggatt gttgtcctgc ttatggatat
     5401 tttaaaaggt acattggcta cttgtttgcc gatgatcttc cacctttctg ggattaaccc
     5461 tctttggttt ggggtatgcg ccattcttgg ccatacattt ccgatttttg ctgggttcaa
     5521 aggaggaaaa gctgttgcga caagtgcagg aatgctttta ggatttaatc ctgtattttt
     5581 tgtttattct tgtatcatct ttatcgttag tttattttgt acaagtatgg tgagtttgag
     5641 cagtatgatc agtgcagtat tgatcacttt atctacgatc gtccttcctt atgtagctcc
     5701 tgtgattttg gctaagccca attggttact gacgatcatt gcctttttag tttcttcctt
     5761 tatcttttat cggcataaag acaatatcaa gcgtatcaga aaccatactg aaagtcgaat
     5821 cccgtttggt ttgaatagca gcaagaaaaa atcctgatac tttttcattc caaagagata
     5881 aaacgggagt gtgacaaatc gatgtcacac tcccttatta cttacaggat agctttttta
     5941 cacaccttgg taaacggtgt tccctgctaa cttctcggtc acaacctctt acttcactgt
     6001 gatggaatat tttgtcttga agatttcatg ggcacctagt tgattgatcc ctactttttc
     6061 catcaagttt ccactactgt tcaccgtgtc agcgattccg caccacggtt cgatacaaac
     6121 gaaaggcgct tcttttggat aaggagacca gatccctaca taaggcatat ctttatagct
     6181 taaagttacg ctatgggaag atttttcact tcgaatggcg tacgcattta gaccccttgt
     6241 ttcaaaaacc aaggcatctt gctcaaaaag ttcacgattc aaagccagat tcgtatttgt
     6301 ctgacctaac gtcttttgat ccatatcgat gaatgggcct ttcaatggta ggcgtaatct
     6361 tgatttcaat ggagaaaatg ccagatagaa atcttcaaat gacaatcctt cttcaagagg
     6421 tacattgaaa gcaggatgtc caccgataga aaagaacatt tctttttcac cggtatttgc
     6481 cacttgataa tgaaccgtga tgccgtctcc tcctaattca tagctgatca ctaattcaaa
     6541 atcaaatgga tacttttcta atgtctccgg cgtactcctt aagatgaaac tagccatttc
     6601 ttgtccatgt tcaatgactt caaaatccat atcccgagca aatccgtgtt gccccatttg
     6661 atatgttttc ccttgataaa catactgatc atcttttaaa cgtccaacaa aagggaataa
     6721 aaccggtgca tgtctgcccc aatacgctgg atcaccttgc cagatatact ctaaaccatg
     6781 ttcttttgat ttcagactga tcaattccgc accgtgttca gcgatttcgg cgatcagctg
     6841 gtcattttga ataataacag tcattgccat tcctccaact tcgacttact ttttaaaatg
     6901 ggaaggctgg aacaaacatt tctatctgcc ccagtcccct tacttctaat aactgtgttt
     6961 tgctaactcg tctttaaaac gggaattcaa tacttttaaa taagttccct tcatgcctaa
     7021 cgaacgagat tcaatgattc cagctgattc caattttcgt aaagcattga cgatcacaga
     7081 acgagtgatg ccgatactat cggcaatatt agaagcagtc agacgacctt catctccatc
     7141 caatgcttca aagatagctt gtacagcctt caattcgcta taagataatg tgttgattgc
     7201 catttggaca gccgttgcac tccgtacatc tgcttcgatg cttcgagact tctgataaag
     7261 gatctgcata ccgacaaccg tagctccata ttctgctaag actagatcgt catctgcaaa
     7321 cgattgttcc atacgagata agataatcgt acccaaacgt tcgccagctc caaagatcgg
     7381 aacgacagtc gtcagaccaa atggatattt ctctcttgac tctaccggaa atgcagtaat
     7441 atcactagta attgggatat tagcttcagt tttcatcaac tgtgccactg tatcagtata
     7501 agattcagga aattgtttct caacaaacat tgttttgatt cgttcattgt tcacatcgtg
     7561 acgttcatta taacctagta atactccgtc acttcctatg atataggtgt tgctgtcaag
     7621 aataccacct agtgtgacag ccattttatc gtaaggcaaa tctgcttgca tgtcaaaagt
     7681 attcttttgc tgcaaaagtg tgtttatctt gcgggttttc gttagcaagt ctgtcattgt
     7741 cgtcctccga ttttttataa aatatagcga cttaaatctt catttgccgc aattgagcca
     7801 agtttgtcat ccacatatgc ttctgtgatc gttatttctc ccatttgcat atctggtgct
     7861 tcaaataata gatcttctag tagtttttcc aaaatggtat gcagtctgcg tgcgccgata
     7921 ttatctgtgt cacggttgac atcgaaagcg atttgagcga tccgttcaat tgcttctttt
     7981 gtaaacgtaa ctgacacatt ttctgtaccg atcaacgcga cgtattgttt tactaaagca
     8041 ttatttggtt cggtcagaat cttcacaaaa tcttcagctg tcaaatcatc taattctacc
     8101 cgtatcggga agcgtccttg aagttctgga attagatcac ttggtttaga caaatggaaa
     8161 gctcctgaag caatgaatag gacgtgatct gtttggatga tcccgtattt tgtgtttact
     8221 tgtgaacctt cgacaattgg caatatgtct ctttggacgc cttctctgga tacttctcca
     8281 gattgctgtg atttagaagt gatcttatcg atttcatcga taaaaataat tccactttct
     8341 tccgctaatt tgattgcctc actatggata tcagcatcct tgactaattt tgctgattct
     8401 tccttgatca ataactctaa agcttctttg actgttaccg tccgttccac ttttttcttc
     8461 ggtgtcaaag cacctagagt ttcatttagg tcgatcccca tttgctccaa tccattgttc
     8521 atcattggtg caggtttctt ttggtcttca acttcaatgg ttacttcacg actatccagt
     8581 aaaccctttt gtagttgttc caagactgta cggcgattga ttcgaatatc ttctgtcact
     8641 tcttcttgcg gttcagcggt attttgctga ctagcattaa aaagattcat catttgttca
     8701 aattgattag tggattgttt ctgttctttt ttgataccag gtaccaagat ttttaccaaa
     8761 cgtttttctg catttttttt agcacttgtg tatacacggc tgtactgctc tttttctacg
     8821 atttggatcg cattttctac taaatcccga accattgatt ctacatctct tccgacataa
     8881 ccgacttcag taaattttgt tgcttcgact ttgacaaatg gtgcattgac gatttttgcc
     8941 aaacgtcgtg cgatttctgt tttaccgacc cctgtaggtc cgatcatcag catatttttt
     9001 ggtgtaatat cttgttgcat tttttcatct aactgcaaac ggcgatagcg gttacgcaaa
     9061 gcaacggcaa cagatttttt tgctgcgtgc tgtcctacga tatattcatc taattcactt
     9121 acgatttgtc ttggtgtttg ttttaattca tacatatcta ctcacctctt acagttcttc
     9181 tacgataata ttatgattag taaagataca gatatctgcg gcaatattta acgcattttc
     9241 tgcaatttct ttcgcactca tgtcgttttg agcatagttt ttcattgctc gggctgcagc
     9301 caacgcaaaa ttccctcctg atccgatagc taagatacca tcatctggtg tgataacttc
     9361 tcctgtacct gaaacaagaa gcatttcttt atcattcatt acgatcagca tcgcttcaag
     9421 tttttgcata gattgctgtg tccgccattc ttgagctaat tcgacagctg cgcgttgtag
     9481 attcccgtta tattcgttta gtttgccttc aaatttttct tctaaagtaa acgcatctgc
     9541 aacacttccg gcgaaaccta caacaacttc tccattgtag atacgtcgta ctttctttgc
     9601 agtacctttc atgacaacag attcacccat tgttacttgg ccatctccag ccatagcaaa
     9661 tttcccgtct ttttcgacgg cacagatagt ggttgaatga aatggtgatt cgaccatgtt
     9721 tgtttcctcc taaatttgtt cttttcctta tttttacgct cttggatgga aagaacgata
     9781 gtttttttgt aaactttctt ttgttacatg ggcatagatc tgggtagtcg ataaattggc
     9841 atgtcctagc aattcttgga ctgtccgcaa atctgcccca ttatttaata aatgagtagc
     9901 aaatgtatgg cgcagcatgt gaggatggat atcactatcc aaactgcttt ttttgatcat
     9961 ttgattcaag acatattcaa ttccagtagg cgtgattggt tttccatgat gattcacaaa
    10021 aacgatatca tgctcttcgt gatattttgt catcaatacc tggcggcctt ccctgaaata
    10081 ttcttgcaga gcatcttgag caaaagaacc tagaggagca tatctctctt tgttcccttt
    10141 accatggatc aacatgacct ctgaatcaaa atcaatgtct gataccgaca aactgctaca
    10201 ctcacttaaa cggatgcctg acccgtaaag gacttccagt aaagcgcggt tcctcaaatc
    10261 caaaggacta tctcctgcta cgctgtcaaa aagtgcttgc atttcatttt cataaaaaaa
    10321 acgtggcagt ctcaaatttt tctttttgag atgaacgtaa gaaaatggat tttcttttat
    10381 cacttcttct ttgagaagat actgataaaa cgaacgtagg ctggctatct tgcgactgat
    10441 agaatttctg ctatagctag gacgatgatc agctaatgca ctcaaataga cacgaaccgt
    10501 aaaatattcc gccttcagca gatcagcgtc tccagattcc tccaaaaaat gtttgaaatg
    10561 gagaatgtct tcttcatatg cttctttcgt tttttctgaa tatcctcttt cgacaatcaa
    10621 ataacgcaaa aatttttgtt cccacgtggc ttctgtcatt ttctcacctt ccttttgtcc
    10681 cagagaataa tttagcacag cgtttataaa aagacaaata aattgtcaga atttaaccaa
    10741 tatttctaag tttgttcaca attggcgcaa ttcctcacat tttgtttgag aaattcttaa
    10801 gaaaaacgca agaaaaagag cgagactatc cgtctcaccc tcttcatgga gtttccttac
    10861 tcatttggga ttgcagtttt ttctaattct gtttttattg cctcattagc ttttaaagct
    10921 cgttgtgcaa ttgcttcata tcttgctttt ttgtctcgaa tgcgctctgg cagttcagga
    10981 aacagaccat agttggcatt catcggttgg aaatgttttc cttccgcatg agtaatgtag
    11041 taagccatac ttccaatagc tgtttcttgt ggaaactcga ctggttccat ttcttttgct
    11101 aagcgtgcgg cgttgattcc agcaagtagt ccgctcgctg cactttcaac atagccttct
    11161 acaccagtca tctgacctgc aaagaacaga tcttcgcgtt tcgttgattg gtaagtcggt
    11221 ttcagcaatt ctggcgaatt cataaagctg tttcggtgca tcacaccata gcgaacgaat
    11281 tcagcatttt ctaacccagg aatcatccgg aaaacacgtt tttgctcgcc ccatttcaag
    11341 tgagtctgaa agcccacgat gttgtataaa gaagctgcag cattgtcttg acgcagctgg
    11401 ataacagcat aaggacgttt gccagtttta ggatcttcca atccaactgg tttcataggt
    11461 ccgaaaagca tcgttttgaa tcctcgctgt gccattactt caattggcat acatccttca
    11521 aaatattttt ctttctcaaa agatttaagt tctgccactt cggcattgat tagtgcctca
    11581 tggaaagctt tgaattcctc ttctgtcatc ggacagttca agtaagctgc ttctcctttg
    11641 tcatagcggg acttcaaata tactttatcc atatcgatcg tagctttgtc tacgattggt
    11701 gcagctgcat catagaaata aaaaccatct gaaccattga atgctttgat gctttctgct
    11761 aatggatgag aagtcaaagg tcctgttgct actacggtga ttccttccgg tatttcagta
    11821 atttcttcgt ttatcactgt tactaatgga tgctctttga cttttcgggt aattgtttca
    11881 gaaaaagaat cgcggtcaac agctaaggca ccaccagctg gcactgctgt ttcatctgcc
    11941 gaagtgatta ctaccgaatt caatcggcgc atttcttctt tcaataaccc tactgcatta
    12001 gccaaactgt ttcctcttaa tgaattggaa catactagtt cagcaaaatt acttgtgtga
    12061 tgcgcctcag tcgatttgac tggacgcatt tcatataaac ggacagggac tcctgcttgt
    12121 gcgatctgcc aagcagcttc acttccggca agccctgctc caacaacatt taccattttc
    12181 aatgaaagaa cctcttttct attatttttg gatgtcttct tcgtaatctc catttacaca
    12241 gactacttgt ttaccgcctt tgactttctt ctcgaccaga tatccgtcac attttggaca
    12301 atttctgccc actggtttat cccaagaagt gaattcacat tctgggaaac gggaacaacc
    12361 atagaatagt ctgtttttct tagattttcg ttcaatgact tgtccttcat gacatactgg
    12421 gcaagtcaca ccgatttctt ttacgattgg tttcgtattc cgacaatcag gaaaattact
    12481 gcaagcataa aacttcccat atttccctaa ttttatcacc atcggatgtc cacagacatc
    12541 acaatcgaat cctgctggtt catctttgat ttgaattttt tcgatttttt cttccgcatt
    12601 cgtcagttct ttttcaaacg gtttatagaa acgatcaacc actttgaccc acgcttccgt
    12661 gccttcttca attttatcca aatctccttc catttctgct gtgaaatgga tatcgacgat
    12721 ttgagggaag aattcacaga ttaatgaatt gacaatttct cctagttcag tcggctcaaa
    12781 tcttttttgt gtcaatttta catagtagcg tctttggatc gtatcaagtg ttggtgcata
    12841 agtggaaggt cgccctaccc cgttttcttc tagtgcacga atcaacgtag cctcactaaa
    12901 acgtgctggt ggttgagtaa aatgttgttt tggttcaata tcaacagatt ggactacatc
    12961 gccttcttca agttctggaa gaatattttc tttctcttct ttgccgtcat ctctaccttc
    13021 cacatacact tgcatgaatc ctttgaattt gatttttgaa ccgttcgcaa tgaagatgac
    13081 accattttgt tctaatgtca ctttcattgt atctaaaata gctggtgtca tctgactagc
    13141 cacaaaacgt gaccagatca atgtataaag tttcaattga tctttatcta aatattgttt
    13201 gagttcatct ggtgtacgaa gcacactcgt tggacgcaca gcttcatggg catcttgtgc
    13261 gccttgagca tttttgatct ttcggtgacc atgtctagaa aattcttttc catacgtatc
    13321 ttcaataaat gctgcggcct ctgcttttgc tgtatcggca atccgggtag aatcagtacg
    13381 catgtatgta atcaagccga ctgttccttg tttacccaaa gtgattcctt catataattg
    13441 ctgtgctacc atcatggttt ttcttgttcg aaagtttaac ttacgggcag cttcttgttg
    13501 caggctactt gtagtgaaag gattcgcagg gtttcttttg cgctctttct tttctacttt
    13561 tttaacttcg aagtctgttc catcaattct agcagtgact tcttttacac tttgtgcatc
    13621 tggtaatttc tttttcttac cgtcgattcc ccagaaattt gctttgaatt tcttgcgagc
    13681 ttttttaaaa ttaccgtcga tgctccaata ttcttctgga acaaattctc ggatctcttt
    13741 ttcacggtca ataataattt ttaaagcgac agattggaca cgtcctgcac ttaacccttt
    13801 cttgacctta cgccagagaa taggactgat cgaataacca acgattctgt ctaaggtacg
    13861 acgagcttgc tgtgcatcta ctaaatctac atcgatcgtt cttggttcct taaaagctgc
    13921 tttgactgcg tcttttgtga tttcattgaa gaccacccga tttttttctt tcagatccaa
    13981 cccaagtagg tacgctaaat gccaagcaat cgcttctcct tctctatccg ggtcacttgc
    14041 caagtaaact ttttgagctt tttttgctgc ggctttcagg cttttgatga catcgccttt
    14101 tccgcgtata gaaatataat ggggttcata attgttttca aaatcgatac ccattttact
    14161 tttcggtaaa tctcttatat ggccaacact ggccattact ttatagtttc gtccaagata
    14221 tttctcaatt gtcttggctt ttgcaggtga ttctacaatc actaaatatt tatacgccat
    14281 tactgaatgg actcctttcc attgtcgtgt tcctactatt aaaagaggat tcatacaaat
    14341 cgtagctaat catatccatt cagaaaacgt ttgtcaagaa aagcaaatga aaagtatggt
    14401 gttattcttt aaattctgcc aagatatctt cacccgaaac cgtgcaaact gcaccgtctt
    14461 ggatcaaatg atgacatccg gtagaatgtt ctgttaaaat atttcctgga acagaaaaaa
    14521 ctgttcttcc aagatccaat gcttgctgtg ctgttatcag agagccgctt tttttcttgg
    14581 cttcaaagac acatgttcct ttagacaaag ctgcgataat ccgatttctc attggaaaac
    14641 aatgcttttt cgggccggat tgaggaggat attcactcaa aagaagatga tcatttgcaa
    14701 tcacctcttg caagtcacga ttttcagcag gatagacttg ctctatccct gttccaatga
    14761 ctgcgattgt ccgtccacca tgagagattg ctgcttggtg accgtatgta tctatccctt
    14821 tcgcgcagcc actgacgatc acatatccag cttctatcac tggttttagt aaataataaa
    14881 ctgttttttt ggctaaagca gaagtgtgtc ttccaccaac aacgcttaac atgttacaag
    14941 aaagtaaaga tagatcacca ttataaaaca gtacaattgg cggataggtc aagtgaagca
    15001 gctgaggggg atatttggga tcaaagcaag tgataaacga ctgtttcgat tggattttgc
    15061 cccagttagc gtgaatttcc tgccaacttt tgcgaaacag ctcccggtgt ttggttattt
    15121 tacctatctt aatgatgtct tcaaatccga tttctttata aggatactgc atcatccagt
    15181 tagcaagtgc ccattttcct tgactactga ttccttttgt ataagcaagt ttcaataaat
    15241 tttcttctat ttgatacatc ataaaaccgc ctttcgtctc tctttctaat aagatacgta
    15301 aaagcggctg ttttttattg taaatatttt tttacaggtg caaaactttt acgatggatt
    15361 ggcgtaattc cttgtcgttc aagtccttct aagtgttcct ttgttccata acctgcatta
    15421 tgcgagaaac catatccagg ataaagcacg tcatattctt tcatcaattg gtctcgatat
    15481 actttagcaa tgatacttgc agcagcaatc gacacagatc gtgcatcccc tttgattatt
    15541 ttttcctgct gaataggcaa atccaaggtc atcgcatcga tcaacaaata gcttggtaca
    15601 atggacaatt tttctactgc ttggatcatc gctaatttac ttgcttcata aatattcaca
    15661 tcatcgattg tctgctgatc aacgatcccg atcccgattg ccagggcttt ttcttgaact
    15721 tgttgataaa gaagttctcg ctttttctct gataattgtt tggagtcatt cagccctaat
    15781 atgatctcat ttttcggcaa gataactgca gctgccacga caggtccagc taatggtcct
    15841 cttcctactt catcaatgcc ggcaatccat tggtgacctt gtgcgtaccc ttgcttttca
    15901 aagcaaaaca tttcttcata tttttcctta attaatgctt cctttttcaa tcgtcgttca
    15961 aaagaagcca gtgcttgctg cacgcctttg cgtggatcat ttcttaatga ttctagtgta
    16021 ggatcatcta ttctctgtat gcttttcaat cgttctttga tactttggat ggattcagtc
    16081 atcacttttt tgctccattt cttcgcaacg atccagtgtg tatcgtccaa gttttccttg
    16141 acgaatatca tgcacgacta attcgctgcc acgatcatag tcttctttat acccacgttt
    16201 tgctgtaata tccatcagta attccggtgc caatttttct tcttgctcga ttgataaacc
    16261 ataacgatcg ctgattcttc ctgaataata tcgggcaaaa aagtctaatc cgtaaatcgc
    16321 taaatcatct aaatggacaa gctggtcttt gatcgcgcct gtcagcgcta gttttttgcc
    16381 gatttcttca tcttcaaatt tgggccataa aatccctggt gtgtctaaca attccaactc
    16441 attacctaaa cgaagccact gctgaccttt tgttacgcca ggcttatttc ctgtctgtgc
    16501 aattttcttg cctactagtc gattcatcaa cgtagatttc ccaacatttg gaatacctaa
    16561 gaccattgcc cgaatagcgc gaggcttgat cccccgagca gcatctcttg cccgtttttc
    16621 tttcaatgct tctttagccg caggtactag acctttaatt cctttacttt cttgtgccgt
    16681 gatagctaat gcaagatggc cttgtttacg aaaatattct tgccacagct ttgtctgttg
    16741 tggatctgcc agatccgctt tattcaataa aacaaggcga ggtttttgct gaatgatctg
    16801 atctagcatt ggattacgag aagataaagg taatcgtgcg tctaccaatt caaatacgat
    16861 gtccacatat ttcatttttt cagaaacttc tcgtcgggct tttgccatat gtcccggaaa
    16921 ccattggatg gtcattgttc tctccattcc tttcataccg gaatattccc cggctttact
    16981 tgtttttttc tttttcaata taaattcact tttttatt
//
LOCUS       DADQCX010000064        16880 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.064, whole genome shotgun sequence.
ACCESSION   DADQCX010000064 DADQCX010000000
VERSION     DADQCX010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.064"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(197..1702)
                     /locus_tag="J8R83_001896"
     CDS             complement(197..1702)
                     /locus_tag="J8R83_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9575026.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1699..2385)
                     /locus_tag="J8R83_001897"
     CDS             complement(1699..2385)
                     /locus_tag="J8R83_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9575027.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2578..3999)
                     /gene="gndA"
                     /locus_tag="J8R83_001898"
     CDS             complement(2578..3999)
                     /gene="gndA"
                     /locus_tag="J8R83_001898"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAZ9575028.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4169..4348)
                     /gene="rpmF"
                     /locus_tag="J8R83_001899"
     CDS             complement(4169..4348)
                     /gene="rpmF"
                     /locus_tag="J8R83_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAZ9575029.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4406..4975)
                     /locus_tag="J8R83_001900"
     CDS             complement(4406..4975)
                     /locus_tag="J8R83_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAZ9575030.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5161..6063
                     /locus_tag="J8R83_001901"
     CDS             5161..6063
                     /locus_tag="J8R83_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9575031.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6098..7882)
                     /gene="pyk"
                     /locus_tag="J8R83_001902"
     CDS             complement(6098..7882)
                     /gene="pyk"
                     /locus_tag="J8R83_001902"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAZ9575032.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(7956..8918)
                     /gene="pfkA"
                     /locus_tag="J8R83_001903"
     CDS             complement(7956..8918)
                     /gene="pfkA"
                     /locus_tag="J8R83_001903"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAZ9575033.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9086..12400)
                     /gene="dnaE"
                     /locus_tag="J8R83_001904"
     CDS             complement(9086..12400)
                     /gene="dnaE"
                     /locus_tag="J8R83_001904"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAZ9575034.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            12631..12816
                     /locus_tag="J8R83_001905"
     CDS             12631..12816
                     /locus_tag="J8R83_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAZ9575035.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(12878..14074)
                     /locus_tag="J8R83_001906"
     CDS             complement(12878..14074)
                     /locus_tag="J8R83_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9575036.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14244..15680)
                     /locus_tag="J8R83_001907"
     CDS             complement(14244..15680)
                     /locus_tag="J8R83_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAZ9575037.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            15973..16782
                     /locus_tag="J8R83_001908"
     CDS             15973..16782
                     /locus_tag="J8R83_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9575038.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         4942 a         3543 c         2958 g         5437 t
ORIGIN      
        1 tatttttaaa cacgaatatt acagcatttt attgtttttt cgttcatcta aaagatactt
       61 acatttaatt aacggatgtt attctattta attgttcgct agttttttta taatgacatc
      121 cctgaatttc tcacttgctt gtattttgta ccttattctt tgttggatat ataaaaaaac
      181 aagtaaagca catgctttac ttgtcttctg cctttgcgat aggaataaag attctaaaaa
      241 ttgtcccttg ccctactaca ctttctgcta agatacgtcc tttatagttt tcaaccagtt
      301 gtttagcgat agacaacccc agaccatttc cacccttcgt tctagctctt gctttatcca
      361 ctcgataaaa acgattgaag atcttattaa ggtcttcttt gggtattcct tcgccaaagt
      421 cctgaatcgc gatctcaaat tcattcagag tggaagaaat agagatatgg acttcttttc
      481 gtgtagttga atactttact gcgttatcca atatgataat gattaattgt tcaaagtgat
      541 tacgataaat ttgcagggtc acttcttttg tcaaatcatc atctaaagtg atcacatagt
      601 ctggatataa tatcttgaaa ttattataaa cttgataggt gacttctttt cctttagttg
      661 tttcattcgc ataatgaaca tctacttgtt ctgctcttga taagtctagc atctcttgaa
      721 ctaagctttt catacggctg atttcttgca tgctggcgct taatgattct tctaatatct
      781 caggatcatc tttcccccaa cgatttagca gactaagatg cccttcaata attgcaacag
      841 gtgtccttaa ctcatgagat acgtcttcca cgaattgctc ttgttgttca atatacaaac
      901 gcatacggtc aagcatctca ttgaatattt cagctaaatc tgccaattca tcatttgtgt
      961 cgatttcagg catgtggata tctgattgcg gatctttacg tatagtatcc attgtatctc
     1021 tgagtacctt gagtggtttt aagaaataag aagataaaaa gaaacctaaa atactactta
     1081 agatcaaaga aacaacttct aaaacaataa gagtcaataa tagcttattt cgaatatcat
     1141 agaaagaaga taattcatag aagctttgcg catagccgat cttttctctt gtacctttag
     1201 aatatatagg ctggatagat aaaaagccag tttttccttc tagtgtaacg atcgttggaa
     1261 ctttacgtgt agtctgaatc aggtttcgac tgttttcatg ggttttaaaa atcaagttct
     1321 cgtccaaatc ataaacataa agatccattg atggctgccc tagctcagct ataaaggaat
     1381 cgatcttcat taagtttcct tcgaccagtg aagtatgatc tacgacctca tctccgtcat
     1441 ttgtcgcttt cgtcagatta cgatacgtat ttactaatgt cagttcttca tccgagttag
     1501 ccaaacgaga agctacttct gaaatcgtac gctctacatt gtttctttct tttgccacaa
     1561 tcagattgat agatgattta taggtaatga cagcgaaaat tgtaaacaca acgaatatga
     1621 agaaagaact cgcaaaggcc cacttgattg tcaaggaggg ccctttcagt tctctttttt
     1681 ccgatttttt cggctttatc acgagcgcat cacataacct gttccgcgta cagtttggat
     1741 atagctttcc tccccgggaa cgtcaatttt gttgcgaaga taacgaatat atacgtccac
     1801 tacgtttgtt tcaacttctg tttcgtatcc ccacacttta tttagtaaaa cgtcacgtgc
     1861 taataccacg ttcacgtttt ccattaaagt aagcagcaac tcgtattctc tttttgttag
     1921 ttcaattact tcatttccgc gacgtacgac acggttttct ttttcgatag tcaaatcgcg
     1981 ataagtaata gtagtttgtt tagccacatt tttatcgcct tcaatatcga ttcgacgcaa
     2041 caatgcacga agacgtgcta ataattcttc gatagcaaat ggtttgacga tgtagtcatc
     2101 tgctccgtgg tcaagtccag atacacgatc gatcacagaa tctcttgcag tcatcataat
     2161 gattggtgta tttttgactt ggcgtacacg tctgcagact tctaaaccgt tcaattctgg
     2221 gagcatcaga tccaacaata tggcatccca ctcattattt aatgccgcat ctaaaccagt
     2281 tcggccgttg tagtggactt ctgcgttata cccttcatgc ttcaactcta gctcgacaaa
     2341 tcgtgccaag ttcttttcat cttcaatgat tagaatattg ctcatttatt attttatcct
     2401 ttctattcta ctggcttttt aaaaactcta tcattatacc gataatatgc ttaaaaatct
     2461 atagtcattt tattatggat agcaatttta aaaaagagct gaagtctact cataacaatc
     2521 gacttcagct ctttcgtcct ctttttattt tctcatttcc taacagccga aagactatta
     2581 ttcttcatgg taccatgagt aatggaagat tccttctttg tcgacacgct cataggtatg
     2641 tgcgccaaag taatcgcgtt gggcttggat tatatttgca ggcagacgtt ctgctctgta
     2701 tgaatcgaag taagcgatgg ctgatgagaa agtcggtaca ggtacgccag cttggacagc
     2761 caaggcaacg acgtctctga ctgattgctg atattttttc gtgatttcaa cgaagtaatc
     2821 atctagcaat aaattttcga tctcaggatt tttgtcatag gcatccgtaa ttttttgcaa
     2881 gaatcgagct cggatgatac atccagcgcg ccagattttt gcgatttcac caaatggcaa
     2941 gtcccaatca aattcttttg aagcgacacg taattgagca aatccttggg cataactcat
     3001 gattttactg aaatacaacg cttctcggat tttttcgacc aattcttttt tgtctcccgt
     3061 gaactcaaaa tcgttcgtac gagacaaaat cttgcttgct tgtacgcgtt cttctttata
     3121 agcagaaata tagcgggcaa atacagattc agtgatcaat ggaagtggca cacctaagtc
     3181 aagcgcgctt tggcttgtcc atttacctgt tcctttattc ccagctgcat caaggatcac
     3241 atctactact ggtttacctg ttccttcatc gtctttacgt gtcagaatgt cagcagtgat
     3301 ttctatcaaa tagctgtcta attcgccttg attccattct ttaaagatat cagccatttc
     3361 ttctactgaa aggtttaaaa tattcttcat taagtcataa gattcagcaa tcagttgcat
     3421 atctccatac tcaataccgt tgtgtaccat tttcacataa tgtccggctc catttgggcc
     3481 aatatatgtg acacatggtg ctccgtcttc tgcttttgca gaaatttgct ctaagattgg
     3541 tgcaactagc gcataggctt ctttttgtcc accaggcatg attgaaggtc cttttaaagc
     3601 tccttcttca ccaccggaaa cgcctgtacc gataaagttg atgccagagt tggctaactc
     3661 ttcattacga cgcatcgtat ctttaaagaa tgtatttcct ccgtcaatca aaatatcgcc
     3721 tttatcaagg tgaggaagta actcttggat tgttgcatct gttgccggtc ctgctttgac
     3781 cattagcaag atccgacgtg gtttctcgat agattctaca aattcttcga ttgtatatgt
     3841 tgctttgaaa tttttatctg ggtgttcttc tactacagcg gttgttttag cccctgtacg
     3901 attgaataaa gccactgaat agccgcggct ttctatgttc aaggctagat ttttacccat
     3961 aacggccata ccgacaacgc cgatttgttg ttttgacata tgaactcctc ctacatacgg
     4021 gatttctccc taatctctta cattatagct taacacggct acattgcaaa ctaaagaaca
     4081 acatattttt tatttaccga ctacaaaaaa ataaacctca aggctccatg gttagccttg
     4141 aggttttaca ttttctaatt aaaatgtatt aagcttcttt tgacattacg tccttaccat
     4201 catagtaacc acaatttgca catacgtgat ggcttttttt catttcacca cagtttggac
     4261 attcgtttaa ccctttgatt gtcaatttgt agtgtgtacg acgttttgct tttttagctt
     4321 ttgatgttct tctagctggt actgccattt tgctacacct ccttgtaaag tcttgtatct
     4381 aaattagaca caatatattc caatcttact tgttatcgtc gtcttttgat ttagaatcaa
     4441 aaagttcaga tagttttgca agacgaggat caattttatt ctcggcttct tccatttttc
     4501 tgcgctggta ttcttcttcg gaaacaactt cccaatcatt gccttttgga agttctgttg
     4561 ctgcttcctc ttcttttgtc aatacccgca ttggaatcgc caataagatg ttgtcttcaa
     4621 tcgactctgc taaattcaat aatggacctt caattagcaa aatctcatct gcagacattt
     4681 gttcatctct actttggaat tgttcttctg tcatgaatac ttcgtctaca gaaaaatcca
     4741 tgggcagttc aacaggttct agtgaacgtg ttgaaggaac tgtcaaagtc gtctgcacag
     4801 tgtaatgaac gatatagcct ttcttatcaa ctgagaccaa accttcgact tccactggcg
     4861 caacatcaag tattaaattg tctcgcttca tgagagcggc tttcaagtcg agcgtctcat
     4921 gaaaagttaa cggtgtctcc tggtattttc tcaattccaa taaagaccat ttcatttttc
     4981 atcactccta agcaacaaaa gcaattatac agggcaaaaa gcatgttgtc aatgaaattt
     5041 tcttgacacc ttgcagttca taaaaaaaca gaaaaatctt tattagaaag cctctgtttg
     5101 ctatcatcct cagaatcatt tacaataatc attattccat taaaggagcg gatgatcttc
     5161 atgaacacga aagatatcga atactatgtc caaatcgtca aacaaaaaaa ttttacgaaa
     5221 gtggctaatt atttccgtgt gagccaacct actattacat atgcattaca acgtcttgaa
     5281 aaagagtttg acaccgtact tattacaaga gatcgatcgc atcacgaatt gatcgtcacg
     5341 ccttctggaa agcagctgtt tctccatgca caaaccattc tccaagagat ttctactgca
     5401 agagctgaaa tcactcagtt gcaaaagaaa aagcttcgtt ttggcatgcc tcctattatc
     5461 ggcaatgaat actttcctaa actgtcaagt tactttatca agcatgaatt gatgaatcaa
     5521 attgagatta ccgatggagg ctctcgggac ttatacggga tgatccgaca agggaggatc
     5581 gatttagctg tattaggctc aacacagcca atcgtggatc aatatttaga aacagagtta
     5641 cttttggaca aacgtttcat gatcgtcgtg ccacctacac atcctctttc caagcaggat
     5701 actgtctctt tcaaagatat agcagatgaa cagtttgtac tattgaacga acattatgtc
     5761 caccccgcag cattcactaa gctttctaaa caaacacata ctcatccaaa agttgtttat
     5821 caaagcaatg acttgacgat tttaaagagt atggtccgag aaaatgtggg tatcggtttt
     5881 ttggcagaga ttgctgtcca tcctgaagat catttagttt gcctccctct ttcagatgaa
     5941 gttcagcctc gcttcttgat ttcattggca aaacgaacac agcagatcgt cacgcctctt
     6001 caagaacaag tagtccaagt tatccatgaa ttcgttacag cacaaaaaaa cagctcttcg
     6061 taaaagaaga gctgttttta ttttttatta agctaaatta gatagctgtt gtttcgccac
     6121 ggtaaacgat gccgcgacgt gaatcaacgg taatcaattc accttctgta attgttgttg
     6181 ttgcgccttt agcaccaacg attacaggaa tatcttgtgc aattcctaca actgcagcgt
     6241 gagaagtcaa tccgccttct tcaacgataa cagcagctgc tttttcgatt gcaggcatat
     6301 attctttgtc agttgatggt acaactagaa ccattccgtc ttttgctttt tttacagctt
     6361 cttcagcaga tgaagcaata actgcatttg caacgacaga tttttgtcca acgccttgag
     6421 cttctaataa tttagaacca atcatttgaa ttttcatcac gttagttgtt ccgcgttcac
     6481 caactggtac accagcagtg atcaagatta aatcgccttc tgatgcgaaa cctaattcaa
     6541 cagctttttt agctgctagt tcaaacattt catcagttgt tgatggtttt tcagcaactg
     6601 ttgggtaaac gccccagttt aacatcaaac cacgttttgt gcgttcgtca aaagtaacag
     6661 ccaagatatc tgcatctgga cgatattttg aaatcatttt tgcagtgtat cctgattcag
     6721 ttgcagcaac gattgttttc acgcctagat tttttgcagc acgagctaca gataaaccga
     6781 ttgtttcagt tacatctgtt ttatcgaatt cgttcaattg gaatgtacct aattctgata
     6841 atgcattttc agcttcttgg tcgatacgtg ccattgttga aacagcttca actgggtagt
     6901 ccccgtttgc agattcacca gatagcattg ttgcatctgt gccatcaaat acagcgttag
     6961 caacgtcaga agcttccgca cgtgttggac gtgggttttc ttgcattgat tctaacattt
     7021 gtgtagcagt gataactggg ataccagcag cattacattt tttgataatg cgtttttgaa
     7081 ccattggtac tagttcagct gggatttcaa cacccatatc tccgcgggca atcataacac
     7141 cgtcagaaac tttgatgatt tcgtcaatgt tgtcgatacc ttcttgagat tcgattttag
     7201 ggaagatttg aacatgagtc atgtcttttt cttctaagat ttcgcggata tctagaacgt
     7261 cttgtgcttt acgtacaaaa cttgcagcga taaagtcgat atcgttgtct aaaccaaaac
     7321 gaatatcgtc agcatctttt ggagtaatac ctggcaaact aatagaaacg cctggtgcat
     7381 ttaccccttt acgtgatcct agcatacctg catttttaac ttctacgact aattcacggt
     7441 ttgcttcgtc tttttcaatg atttgcatat cgatcaaacc atcatcaaat aaaatgtgtc
     7501 cgccaacgtg aacatcgtca aataatcctg ggtaagtaac cgcgattttt tcttttgaac
     7561 ctacatgttc aggatccata gagatgcgtg tttgatctcc tacttcaaat ttgatgtatc
     7621 ctgcacgacc aaaatcagct tctgttgtgc cttgaacagt tgtacggatt tcagctcctt
     7681 ttgtatctaa aagaataccg acatcttttc ctgtcttttt aactgcttca cggaccatag
     7741 tcatacgtga taattgttct tcatggtcac catgagaaaa attaaagcgg aagacatttg
     7801 ccccagattc aatcaattga gaaataattt ctactgagtt acttgctggt cctaatgtac
     7861 taacgatttt ggtttttttc atttaaaaaa ctctcccatt caattttgtt tatttaaagc
     7921 tgtacacagc ttaaatagct tggtttcttt cactcttaaa atgaaagtga attatttaga
     7981 tcatatagtg ataagtctgg tttatgtttg ttgttttcaa gtgtatcaat gatgtcagac
     8041 gcaacgattt cgttgtcatg gataccgaca cataatccac cttttccttc ttgaagcaat
     8101 tcgacagcgt aagcaccgaa tttacttgcc aacacgcggt cgcgtgcgct tggtgctcca
     8161 ccacggacaa cgtgtcccaa gatagataca cgtgtatgat agtcaccaaa ttctgaaagt
     8221 ttctcagcga attcatttcc gcccattaca ccttcagcca agatgatcaa gcaatgtttc
     8281 ttcccgcgat cgcggccttc ttggattttt ttagcaactg aagccatatc aaaatcatgt
     8341 tctgggatga tgatttcatc cgctccgcca gccacacctg accataaagc gatgtctcct
     8401 gcattgcgtc ccattacttc gataacgaat gtacgaacat gagaagtcgc tgtgtcacga
     8461 atacggtcaa ttgattctag tactgtattg attgctgtat caaaaccgat tgtgaaatca
     8521 gtcccaggaa tatcattatc gattgttcca ggaataccta ctgctgggaa accgcgtttt
     8581 gtcaaagcca ttgcgccatg ataagagccg tctcctccga taaccactag accttcgatt
     8641 ccgaattttt tcaattgttc gattcctttt aattgacctt cttcagttgc aaattctgga
     8701 taacgtgcag aatacaagaa tgtaccacca cgttggatct tgtcacctac atctgccaca
     8761 tcaagacgac gaatatctcc agcaactaaa ccggcaaaac cataattgat cccgtatact
     8821 tccagtcctt cgtaaatacc tttacgaaca acggcacgaa cagctgcatt cattccaggt
     8881 gcgtctccgc cactggtcaa aattccgatg cgtttcataa taaacattca cctcattaaa
     8941 atactttatc ctaagtatga cttaggttta caaccatttt tgcgttaacc acgactaaca
     9001 ttctaacatt atttttctca cttgtcttga tttacggata aaaaaatgaa aaaaaatgaa
     9061 agcaagtagt attttttacc gtaagttatt tgaaaaccac attatcttcg ccaagcagat
     9121 aaataagttg ccgctttata ctcttgctgt catccaccca ataagcatct gacagaacta
     9181 cttttcgttg cgttttttcg tgatacataa ctactggtat atatcctggg tgtttctgaa
     9241 aaatcacttg taattgtttc attatctcgg gatcttcccg ttcttctgta atacgcaaat
     9301 agcaagtttg tgaaggatac tgggcttcta actggttagg atcagcaaag ctttctccaa
     9361 ttagttgcag ttcctgatta tatttgctga tttcgctccg cccttgaaca aagatcactc
     9421 gatcaacggc aaacaaatta cgatatttac gataaagagt tggaaaaact gtgacagaaa
     9481 tttctccact actgtcggtt ccttcaacaa aggccatcag ttctcctttt tttgtccgaa
     9541 tttctctaac ttccttgatc atcactaata aattgactgg ttgattaggg acgatatctg
     9601 taatcagctg aacttgttta gctaaacgaa gacgatcaaa cccttctgca ggatgacctg
     9661 acaaataaat acctaagtac tcctcttcca gcttcaagcg ttcttctagt gtatagtcag
     9721 cgacttcttc ttcttttaat gccatgattc ccagcaagtc aagacttcca ccactgtaaa
     9781 cgatattttg gatttttcct tcgagatcaa gcatcaattg tttcctgtta ggagataatt
     9841 catcaaaaac tcctactgct gtcagtgatt gcagtaactc taatttcagc caacgcttat
     9901 cgatccgtat gaggaattga tccactgact ggaacgggcc attttgtttt ctttcgttta
     9961 atatatcttc tacaaaatca cgccgaatac cttttatcgc tgtcagtccg aatctgattt
    10021 cttccttatt gaccaactca aaactggaat tactttgatt aatggacggc gaggaaagtt
    10081 tgagtttatt tttacgtgct tctgcaatat attctttcaa ttttgatgtg ttatgccgaa
    10141 cagaattcat caggctggta aagaaagcac ctggatgatg ggcttttaga tacgccattt
    10201 ggaatcccac gaatgaataa gcaaatgcat gtgaccgatt gaatccatag tttgcaaatt
    10261 tttcgatata ttcatatacg gtcgctgctg ttttttccga atatccctgt tgtaatgctc
    10321 ctgatacaaa atgcgacttt tcttcatcta atacgtcttt tttcttttta ctcactgccc
    10381 gtcgcagaat atctgactgc cctaatgtaa atccagccat agtcgaggcg atctgcatga
    10441 tttgttcctg atagacgatc actccatatg tgtttttcaa aatcgggatc agtgaatcat
    10501 ctgggtagcg aatggcttct tttcctttct tcctggcaat gaaggtatct atattttgca
    10561 tagggcctgg tcgatacaat gcattgactg cggcaatatc ttcgatgttt tctggatcta
    10621 atcttcgtaa aacgttccgg ataccagcag attcaaattg aaatactcct gaggtttcgc
    10681 ctcgttgaaa caagagcagc gtttttgcat catttagcgg gatctctttt aatcggatct
    10741 catacccttc tactcgctta acagctttca aagtaaaatc aataatcgat aagttgcgta
    10801 gtcctaaaaa gtccattttc aaaagaccga ttgcttctac ctcattcatc gtatactggg
    10861 tcagaaaagc ttcatcagaa ccgcgttgga gcggaactag ttcaagtaga ttcttatcgc
    10921 tgataactac acctgctgcg tgagtcgaaa catgtcttgg caatccttct aaaatcactg
    10981 cagttttgaa taaaagttgg tttttttcgc ttgcctgaac taattctact aattgatgcg
    11041 aagttttata agcttgggtc aatgtgattt tcaattgatt gggtattgct tttgaccagc
    11101 ggtttgcttc actttgcgat aaaccaaaca ctctagctgc atctctaaga accatttttg
    11161 ctgccattgt gccaaatgtt gcgatttgtg ccatatgata ttgtccatac ttttctcgaa
    11221 cataattcaa tacttcttca cgtcgattgt caggaatatc caaatcgata tctggcatcg
    11281 taaagcgttc ggggtttaaa aagcgttcga acagcaaatc atattctaat ggatccacat
    11341 ctgtgatttc taacacatag gctactaatg aacccgcagc agaaccacga cctgcaccgg
    11401 taacgatttt gtttctatga gcaaaagcca ttacatccca tacgatcaag aaataatcat
    11461 cgaatcccat ttgatggatg acagataact cgtagtccaa acgttcttgg tattcctttg
    11521 tatagtcagt gattcggcgt tccacttgcg aatagcataa ctctcttaaa tattctccag
    11581 cttgttttcc attaggaact ggataatgcg gaagtaattt ctgatggaac tggaattcaa
    11641 atgaaatcga ttcagctaaa cgctgggcgc ctattacagc ttgggaaaga cccgcttttt
    11701 cgaatcgttt gatcatttct tgttctgaaa gaagatagac atttgctgtt agtggtaaag
    11761 atgcagataa attttctaaa ggtatttggc ttccctcttt gatatgtttc atcacttcaa
    11821 gtgcaaaaag ttcttcttgt tgtaaactag cgatgggatg taatgcacaa agcgaataat
    11881 tttcttttat cacatactga taccattcag gcaattgatc aggcgtgttt tctgtcaagc
    11941 cgatataaaa atttctagta aaaacatttt caagtaaaaa ctgccaatga ccgaaaaagt
    12001 tatcctcttt attgaaagcc tcagaaacag aatgatttgc cggaacaaca aacgctagat
    12061 ggtcggtttc tgtcatttct gcaagttcca atttttcttg gatcattttt cggctggaaa
    12121 gtttcatcag ctgctgataa cctatttcat cttttgcgta cgcaagcaag ccataatttt
    12181 tttcttcata agtataacta agatgtaatc caatgattgg ctgtactcct tcttctacac
    12241 aaatacgata gaattcaggt gcaccgtata agacatcttt atccgttatg gctaatgaag
    12301 tgtagccttg tttttttgct tcttgtacat attctcgaat acgtatcgta ctttgtaaaa
    12361 gagaataaga agtaattgta taaagttgtg ggaaaaacat cttgcattcc gccttttttt
    12421 tcgttaaaat tcactagcgt taaaaggttt gatcctttta ctttcattaa gatagcaggc
    12481 gctgaagttg attattccac ttcatttgct tgcttgtaat ctgtaggaat gagttctttc
    12541 gcaagaactc aaattttatt gagatttggt ctcgtttctt tacattcaaa gaaaatctgg
    12601 taaaattaag atagaaaaga ggtgttcttt atgcgatata tcgttacatt attctgggct
    12661 gtcgttctag gtcaagtagt cggttatatt ggtgctgcat taacaagcgg aacatatgat
    12721 tttactttga caacaatcat ttcattcatt gcgggtgtca ttatcctttt gattggtgca
    12781 gttgcgccaa gaaaagaaac ctctgcccat tcgtaaaaaa acagccaaga gcttgagatt
    12841 tctcaagctc ttttttattt tctactcctc accaccatta taatctgctg cgaagaactt
    12901 tacgaaagtt gaataaagaa agaagaatat ttgacagaac aaacaaactt gtcacaataa
    12961 aaacagcact gtaattataa gcatgcgcga ctgtcgatcc tagcatggga cctaaaactt
    13021 gtccaaagtt gctaaacatc tgattgtagc tatagattcg gctgactcct tcttgaggcg
    13081 taatcttact gatcagtgta ttgacagaag gcatcaaagc gccagttgaa aagcctaaaa
    13141 taaagcgaag tatacctaat tggagcggtg tagtgacgaa tgccataggt aaataacagc
    13201 aaaatgataa aatgagtcct ccaattagaa ctttttgatt cccaatctta tcccctagtt
    13261 ttcctagttt cggtgaagaa aagacagcgg aaacaccagc tatcgaaaca atcaagccgc
    13321 tgacaaaaag gatattttct gtacttccgc tcaattcacg aatatataag gtcaaaatag
    13381 ggctgatcgt agtgattcct atctgtaaaa tcaaggtcgt aatgaagaga ccgatcaaaa
    13441 tagagagatg atccattttt gaaaaaattt ctttggtgct tatcagatct tttttctcga
    13501 ttggatggaa atcttctttg actaagaaaa tggtcaatac cgttgtgatc atcaacaaag
    13561 cccctgtgat caagaataca ttttccatac caaaccactg agccagtgca ccgcccattg
    13621 aaggtccgat cagatttcca gcaatcgctc cggtagacaa tgttcctaac gcccatccgc
    13681 tcttttctct aggtgcctgt gaagcaatca tcgctgtggc atttggaata tatccagaca
    13741 aaatcccatt ccaaaaccgc atgatcaaaa gccaatacgc gtttggtaca aaagccaaag
    13801 atcccattgt taatgtcatc cctgctgctg cacggatcat catgagtttt cggccttttc
    13861 gatcagctag atttccccag attggtgcaa ccacggcaga tgcaaaagca gtcacagaga
    13921 ttgctagtcc cgaaaacaat tcgatttgat cttttggtgt tcctagttgc tcaacataaa
    13981 ctggtatgaa tggcataact aaactaatac ttgcaccagt gaaaaaacag ccaatccacg
    14041 caatcactaa attttttctc caattaatct ccatctatca tccctctttc gtctctttta
    14101 tcatacctat tttcgaataa acaagcaacg atctcgccag taaaaagaga aaaatcccgc
    14161 aaaggtcatt ttatatgtaa cgttcttttt atgtaaaaca aaaagagatc agaacaaata
    14221 ctgttccaat cccttctctt tagttaaatt gttgctagaa tgatgaagtt gataatgaat
    14281 aaaatatcaa cgatccacaa agcaacagaa acttgattgt attttccttt gattactttc
    14341 acaattgtat agaaaataaa tcctgctgca atcccatagg aaatgctata gcacaatccc
    14401 ataaagatcg atgcaaagaa ggccggtaaa gcttcttcca tatctagcca tttgatgtct
    14461 gcaaaagaag ccatcatcat tactccaact aaaatcaatg ctggcgcagt tgcttgattt
    14521 ggtacaatgg cgatcagtgg agagaataaa ctacttaatg cgaatagcac tgccactact
    14581 actgaagtca aaccagtacg tccaccggcc ccgatcccag ctgcagattc gacataagtt
    14641 gttgtattcg atgtaccaaa gatagccccc acagaagtag cgatcgcatc ggcaaatagt
    14701 gctttatcca tttttgtttt gaacccacga ccatcttcca acgcgatctc gtcttctttt
    14761 gagaaaatac ctgtgcggcg tcctgtaccg ataaatgttc cgatcgtatc gaaagtatca
    14821 gataaactga atgcgatgat cgtcatcaat acttgaggaa tcttggaaga atcactgaat
    14881 aaagattgca tgccttcaga accaaatgct gcaccgaaag ttgttcctaa ttctttaaat
    14941 gaattaccta acgaattcgt ttgccaatca atggaactta aatcaacaac acccataaaa
    15001 ataccaagga ctgtggtcgc tacgataccg ataagaatag ccccacggac attttttaca
    15061 actaaaatgg ctgtcagtac caaaccaatc acagccaata agataggagc gttgtcaaag
    15121 ttggctaacg cagggacgat tccaccattt atcgtaacat ttgtcgcttt tccgccttca
    15181 acgacagagc tcgaaatagc tgactggtct gctgaaaaag ataagaatcc tgcatttttg
    15241 attccgacat acgcaacgaa aataccgatc ccgccaccaa tcgcatgttg aagactttcg
    15301 ggaatcgccc gaataatcat ttttcgaata tttgtgacag taataaaaat attgattaat
    15361 ccgcaaataa acaccattgc caaggcttgt tgccaagaat aaccaagccc aaaaacgacc
    15421 gtaaaagtga aaaatgcgtt caatcccata ccaggtgcct gagcatatgg tacatttgcg
    15481 aacaatccca ttaccagcgt accaataatc gatgcaatga ttgtcgctag aaatactgct
    15541 tggaagggca tacctgatgc tgacaaaatc gtcggattta cgaataagat ataactcatg
    15601 gcaaagaatg tcgttactcc cgccattatt tcagttgata catttgtatt gtttttcttt
    15661 aaaccgaaaa acttttccat aaaaagttcc actccctgaa tttttttctg atggaaaact
    15721 ataataataa aaaataagta aaatagggca aatccatcga acaatttcaa attatataga
    15781 cgtttcattc gcttttcaac gtttttttaa caaaaaaagc gaaaataata cttaacgttc
    15841 gtgtttagct tatgtttagc tatttatata gccataactg tagtttttgt taggaatagc
    15901 tgattgctct tgttaattac ctaaaatatg ctagactaaa acaaatgcta gttgaggaag
    15961 gaaggaccct tattgaataa aaaattaatt gccatcgatc tggacggaac taccctcaat
    16021 caagattcga tgattacatc taaaacaaaa gagactctaa aaaaagcaat caatgccggt
    16081 catcatgtca gtattgctac aggacgccca ttccgaatga gccatcagtt ttaccaacaa
    16141 ttagaattaa caacaccgat ggttaatttt aacggcgcat tagtacacat ccctaatcag
    16201 cactgggatg gtgaaagaga aacgttgatc aatcgtgaaa tcgcttttga aatcttatcg
    16261 caaaaaaagc agctaaattt agattttatc gctgctgaaa atcgtgatac tttttttatt
    16321 gacagttttg atttctttga tgaaaaaatt tttgcttctt ctcgtccagg agagaagaat
    16381 ttgctttctc ctaaaaattt gacgacaaat cctacatctt tgcttgtccg aacagacaaa
    16441 cgttttgcag gagctgtatc tgctgaatta acacgtcaat ttggcagtta tgtcgatgtt
    16501 cggacatggg gtggacctac tgccatctta gagattgttt caaaaggaat ccaaaaagca
    16561 aaaggcgtgc aagagattgc taactacctg tctatcgatc aaaaagacgt cattgccttt
    16621 ggtgacgagc ataatgattt ggaattgttg gattatgcag gttggggagt agctatggct
    16681 aacggtactg accaactcaa aggcattgca aatgatgtca ctcctttgag caatcaggaa
    16741 gacggtttag ctgtttatct ggaaaaacta cttaaactat aatagagaat tagattccac
    16801 aaaaaagagg ttgtgacaat ttttgggctc tataatttat gggactgatg aatcagaatt
    16861 gattcttcag ccccattttc
//
LOCUS       DADQCX010000065        16271 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.065, whole genome shotgun sequence.
ACCESSION   DADQCX010000065 DADQCX010000000
VERSION     DADQCX010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.065"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(56..712)
                     /locus_tag="J8R83_001909"
     CDS             complement(56..712)
                     /locus_tag="J8R83_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9575039.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            905..1183
                     /locus_tag="J8R83_001910"
     CDS             905..1183
                     /locus_tag="J8R83_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575040.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            1202..2410
                     /locus_tag="J8R83_001911"
     CDS             1202..2410
                     /locus_tag="J8R83_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9575041.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2558..2923)
                     /locus_tag="J8R83_001912"
     CDS             complement(2558..2923)
                     /locus_tag="J8R83_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAZ9575042.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(3070..3843)
                     /locus_tag="J8R83_001913"
     CDS             complement(3070..3843)
                     /locus_tag="J8R83_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9575043.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(4017..4877)
                     /locus_tag="J8R83_001914"
     CDS             complement(4017..4877)
                     /locus_tag="J8R83_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAZ9575044.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(4877..6295)
                     /locus_tag="J8R83_001915"
     CDS             complement(4877..6295)
                     /locus_tag="J8R83_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9575045.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(6352..6801)
                     /locus_tag="J8R83_001916"
     CDS             complement(6352..6801)
                     /locus_tag="J8R83_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9575046.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(7246..7509)
                     /locus_tag="J8R83_001917"
     CDS             complement(7246..7509)
                     /locus_tag="J8R83_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAZ9575047.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(7608..8903)
                     /locus_tag="J8R83_001918"
     CDS             complement(7608..8903)
                     /locus_tag="J8R83_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAZ9575048.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(8900..10171)
                     /locus_tag="J8R83_001919"
     CDS             complement(8900..10171)
                     /locus_tag="J8R83_001919"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAZ9575049.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(10336..11205)
                     /locus_tag="J8R83_001920"
     CDS             complement(10336..11205)
                     /locus_tag="J8R83_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAZ9575050.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(11497..13107)
                     /locus_tag="J8R83_001921"
     CDS             complement(11497..13107)
                     /locus_tag="J8R83_001921"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAZ9575051.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(14300..15640)
                     /gene="glnA"
                     /locus_tag="J8R83_001922"
     CDS             complement(14300..15640)
                     /gene="glnA"
                     /locus_tag="J8R83_001922"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAZ9575052.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(15668..16060)
                     /locus_tag="J8R83_001923"
     CDS             complement(15668..16060)
                     /locus_tag="J8R83_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9575053.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4640 a         3448 c         2765 g         5418 t
ORIGIN      
        1 cgtttgtttc tctaatactc aggtcaaaac gctgatttca caacctcttt gttcatcaaa
       61 agataatatt gtcttctaac aagtccatat tcaaaataac gatatgatgg tctttaacgg
      121 tgataatacc atcttttttc agttgtttta aaattctgtt tacactgcta gcagttgaga
      181 tgccacaaaa tttggcgatt tcttcattcg tgatcgaaaa atcgatcagc atcccttctt
      241 ctgtccgcac accgaataaa tcatataatt cgtaaagttg cgtacaaaca gctcccagct
      301 ttccgtttaa tagcatttgc tgcatttttt tcatcgaata aagcagacga tagcggtaat
      361 actcttttac atagtgttgt agctttgggt cttggttgat attttgccaa aagcgcacac
      421 gattgattcg ataaaactct gcatattctg attcaactcg aatattatac ggcgaatcga
      481 tgaattgtga atattcgtct tttaaaagag agacgatttc aagatctttg atatagcgaa
      541 ggttaaattc tctcccatca tttgaaataa cacttgcttt taccgttccc tctttcaaga
      601 tatacgtatg ggaatcttcc atcccttcga atgtcaaata tttatgatat cctttgcgta
      661 taatcggaaa atcattttta tccaaatatt cctttaagac tctactatcc aatgatgctc
      721 ccccatccaa actttcatct aaaaagatca tacagtactt taaaactttt taaagtccaa
      781 aggtatttta ctaatgatat taacatttgt taagtacctt tttccatcac ttatgcgatt
      841 tttttccttt tttttattcg ttatactgca gaagtaaaat tttttaagaa tagagggaaa
      901 aaacatgaat tactggatga acacaatcat taatcgatta gaaacagcat atcaaacaag
      961 atttgatatg aaagcttctt tagtcttttt aaatgatgcg tatcaaaact cgatcgaatt
     1021 gatcaaagca gtggatgaga atccaacaaa cgaatgcgaa gaatttttaa atctgtttat
     1081 gtctacaaga gatttattta ttcgccaact tgttgatcgc tatccatcca attatcacga
     1141 tgtagaagtt caaatacaaa aattaaaagc atattcagct taaggggaat gtataacata
     1201 catggaaaag aaattattta ataaatattt tattggaatc acattgatca attttattgt
     1261 ctacctgatt tattatctgt tgatggtcat catggcagtc attgcgcaag acaccttaca
     1321 cgccagcttg agccaagcag gttttgcttc tgggatctat atcatcggaa cattgctggc
     1381 acgcttattc atggggaaac agttagaact atttggtcgg aagtttacct taagaggcgg
     1441 cgcgatcttc tatctccttt caacattagc atatctttat acgccaacta tcggggcatt
     1501 gtatttagtt cgattcttga atggattcgg ctacggtaca gtttctacag ctacaaatgc
     1561 tatcgttact gcatatatcc ctgcatctaa aaaaggggaa ggcatcaatt attatggatt
     1621 aagtactagt ttagctgccg ctgttgggcc atttttagga atgattttgc tgaatatgac
     1681 tgattttcgt ttcattatct ggttttcaat tgtactggtc ttctttgtta cgattgcctg
     1741 ccttgtcttt cctgtaaaaa atattccatt atctgaagaa caaaaaatat ctcttcgctc
     1801 atggaatatc aatagtttta ttgaaaagaa agcacttttc attacaggaa ttgccttttt
     1861 gatgggtctt tcttattcaa gtgttttatc atttttatct tcttatacaa aagtaatcca
     1921 cttagttgct gctgggtcat ttttcttcgt cgtatatgct ttggtcatca catttacacg
     1981 tccattgact ggaaggattt tcgatgtcaa aggagaacaa tacgtgatgt atcctagcta
     2041 tttattctta acagcaggat tatttttact gagtgtaacg acgaatagtg tgacattgct
     2101 tatctctgga gcattagtcg gcctaggtta tggtacgttt atgtcaaatg gacaggctgt
     2161 ttgtttaaaa atcgtccgcg aacatcgaat cagtattgct ttatctacct actttattgg
     2221 tttagaccta ggcttaggcg ttggtcctta tttgatgggg atgctaaaat ctcttacttc
     2281 atttagagga ttgtatgtga ttgccggagt cattccattg atatgtacag cactctatct
     2341 tgttaatggc cgaaaacata gtcatgaagc agagggcgaa ttgattgaat cattgaaaaa
     2401 tgaaatttga tcttgatgaa tagataaaaa aaaccgttca gatctgaaaa taatctgagc
     2461 ggttttttga gtaaaaatag tttatgatta ttcttaatta aacatctatt tatttttaaa
     2521 gctttcattt atcgataaga atagtttaac tgttgattta ttccattttc cgttcatctg
     2581 gtacgatgcc ttgacttagc aaccacttgt ggaagaacca ttctgccaca ccgatcaata
     2641 gagcaggaat caatactttc atccaaatat cgactgtatc attcataaaa tatagataga
     2701 gccacaagat aactgcagct gaaccagcat ctgcgatcgt cgctgcgatg ttccctactt
     2761 tacgtaagat caacagatcc cctagcacat agatcatgac tacaataatt accccaacaa
     2821 tcgttgaatc cataaagcta acaccgtata aacctgtcag cacgacccac agaatcgccc
     2881 agatcatgat tgccttcact accaacgcct tcacatgttt cattttctgc actcctttct
     2941 cctggataaa aaagtaagat tatctaacaa gataaccttt tcattattat accatcggct
     3001 gagagaagcg agcaaagata aggtcctatc taaaaatgag gaagccactt agaacattca
     3061 cgtaataatt tatccgtaca gacattcgat atggtgttcc tttactttcg catactgttc
     3121 ttttgtcagt tctttacttg tcaccagata atcgatttca tgaaaagcaa tggcttgatg
     3181 catgaattta tgtgcaattt tttgctgtgt aactaaaacg gcaagccggt ctgattgttt
     3241 tctaaaagct tttttgacca ttgcctctcc ttcatgagtt tctgttactc cttggctgaa
     3301 atctagcccg cgacaactca ttatcgctaa atccgcataa tatgacaatg catcgttata
     3361 ggcttttgaa ccgttgattg ttgctcgttt cggaacaatt gcccctccca atacagatac
     3421 ttttgccgtt gtatattcac tcaacatagc agctgtgacg atgccattcg taatgatctg
     3481 caaaccatca aatcttgcta ggtttctgac taagtgtaaa gaggttgtac tggaatccaa
     3541 gaataagacc atatcatctc gaatcaaaga agaagctgta tctgcaatct tacgtttttc
     3601 tgtttcttct tctaatttgg tgatcttcat caggtaaggc acgtcaattt ttcgattgtc
     3661 aataagcatg gcgccaccgc gaactctacg gatcaatcca cttttttcca gaaaaacaag
     3721 gtcacgttta atcgtggctt cgctataatt tactaactcg atcaaatcgg tgactcttgc
     3781 aaattggttg ttttttagat aattcacaat ctcctgctgt ctattctcca cttcattcaa
     3841 cataaaatca ccccatttac tttatatagt aacaggaaaa aagaggttgt gacagaagtg
     3901 attggcttcg agaaataaga agaaattttt cgaaaaaact acttctgaac atcgtgtgtg
     3961 gttaagaggg tatgacaaga ctattgtcat accctcttga ccacacattt ttatttttag
     4021 tataaactag ccttgcctac tgtgttcaaa atttccattt tatgtttgac cacttcttgt
     4081 acctttttat tagctgctgg ataaattgca ttcggctcgt acatcgatgg attttcactc
     4141 aatatttctc tcaaagcatt gaaaaagacg cttttaagat ctgagctcaa attcactttg
     4201 gcaactccgt attttactgc ttcgctgact tctgcgtccg gattacctga accgccatgt
     4261 aaaacaaatg gaagatcgat ttgttggttc aattctttca gtaagtcgat atttaatttt
     4321 ggagttctgt ttttcggata caagccatgc gctgttccaa ttgctacagc aagtgtatcg
     4381 attcctgttt ctttcacaaa aatcttcgct tgatcaggat ctgtataaat gattgtttca
     4441 gcacctcctt cagcagaacc attattccca atcgttccaa gctcagcctc cactgagaca
     4501 tttaccgcat gagctaacgc aaccactttt ttcgtaatct gtacattgtc gtcgaatgat
     4561 ttcaaagacg catcgatcat cacggaagaa tagccgtttc gaatcgcccg taagacatct
     4621 tctatcgtac cgccatgatc caagtggata acgatcggca gtttacttgt ataagcatag
     4681 gctcttactg ccgcaacaaa ctcatcactt aaataggcga tttcatcagg atgaatttct
     4741 aagattactg gtgcttctaa tctctctgct tcttcgatga ttgctttcat catatcatag
     4801 ctgcaaatat tgaaggctgg tactgcaaat tgattctctt tagccacttt caataactct
     4861 ttcattgtat ataacattac gcttccacct catttgttag attttcattt ttcgtccact
     4921 tgtcttgttt tttctctttc actgtttttt tcaatagtcc aagcataaag gctgtagtga
     4981 ctgtacctga tgcaattgcc aagacataca taggtaaatt gttcataaca tttggaatta
     5041 gcatcaccca aatccctcca tgaggtgcca ttgaagtaac tcctactgcc atggaaatcc
     5101 ctgcagcgac tgctgaacct gtcatcaaac taggtatcac gcggatcggg tcagataccg
     5161 caaacggtat agcaccttct gtaatatacg aagcgcctaa aatccagcat gattgacctg
     5221 aagtccgttc ttctttggta aatttatgtt tgaataataa agtggctaaa gcaataccta
     5281 ggggaggtgt cattcctgca gccatacaag cagcaatcgg tgcatttact ccagctgaca
     5341 tcaaaccgat cgagaaagtc gaaatcgatt tattgatcgg cccacccata tcagctgcca
     5401 tcatgatccc gataagtaat ccgaacaata gcccggatgt atttcccaag ctattcagcc
     5461 aatttgtcaa agcatccaac acccatgtga tcggttgttc aatcacaaat accatcaaaa
     5521 gcccaataat taagatcgat aaaaagggga cgacaatcag ctgataaata gcagaaaatt
     5581 ctttttttac gctaatttta tttgccagaa aatcacagat ataccctgct agcacgccac
     5641 caatcattcc gccaagaaaa cctgaaccac ctgtagaggc cagtaatccg gcaacaattc
     5701 ctggggcaaa acctgctttt ccagcaatcg atgtagcaat ccccgcgcct aacgcaggaa
     5761 ccatcatggc aaacgctgta tctcctccga tccttgaaaa tgcagctgct aacacattat
     5821 agtctgctga gttgggatca gccgctgtaa tcccaaaggc aaaactcagt gcgatgatga
     5881 ttccgcctgc gatcacaaat ggaagcatgt aattcacacc attcatgaaa tgattataga
     5941 ttgtcggctt tttctcattt gcagctggtt ctttttcatt agacacaacg aatacgccaa
     6001 tatctctcaa tgcttcgtct attactactt gcggttcttt gattgctcgg cttgtagaga
     6061 cacgctttac ttttttcccg gcaaatcggt ccaattcgat ttctttatct actgcaagaa
     6121 tgattgcatc tgcctctttg atttcttgtt cagataactg attttctgtt tttacacctt
     6181 gtgtttcgaa ttttgcttga tggtttagat ttcttgctgt tacttctaat ttttctgccg
     6241 acatataagt atgagcaatt ccagtcgggc aagcagttac accaacgatt ttcatgatta
     6301 ttttcctcct ttttcttcac tatcgatact cggacaaaga ctctactatt ttcattcttg
     6361 actaatctgt ctgatgatat ctgctggcgt agtggcttct tttattccct ttctaaaatc
     6421 tgcattcatc aatcgtctgg agagtgtgct gagaatctct agatgcatat ctgctgattt
     6481 ttcaggaact acgatggcaa aaatatattc aattggcatt tcatctatcc cgctatagtc
     6541 cgttaatttg gctgtatgaa aaaaacacag tgctggtttt gtcacatatt tgctttttgc
     6601 atggggaatc ccaaatccat cttctattcc tgtggagatc tcctcctctc gtttgaatag
     6661 tgccttaacg actttttgaa catttcttac cttatttgtt tttttcaaca catcccctat
     6721 tcgctcaaat aatgatcctt ttgaatctat cgatggatcg aaaacaatca gttcttctgc
     6781 gatcaattga tcaaacctca taaaaaacct ctcccccaca aaaaatgtta acgttttctt
     6841 ggaactgagg tcagtatagc atcgctagct gtaccgttca atattatgaa tgaacagagg
     6901 aaaaagaccc atcatccgcg tgtataagtc attaaaatga acgatctagc tcacaaacaa
     6961 tcgcaagtct ataacaaaac aaaaagcctt ccttgaaagg aaagcttagc ttctaatttt
     7021 aggtaaatgg ttttttactt cgaaataacc cctcttcatt tcgttaatat aaggtgtttt
     7081 tatcaagtgg ataattaaaa ctatatacta gtttttcatt gttttgtgca ttatgatcct
     7141 acgacttttt cagcatcaaa cgaagtttta aattggcaaa aaacataaaa aaacagacta
     7201 tccctatcag atagtctgct aaacgttgag ttatcagcgt ttttattatt ccgcagcgtt
     7261 tgcgtctttg agaccgtatt ttttgttgaa acggtccaca cgtccgtctg cttgtgtgaa
     7321 tttttgacgt ccagtgtaga atggatgtga gtcagaagtt acttcgacac ggatgactgg
     7381 gtatgtatta ccgtcttccc attcaactgt ttcttgtgaa gtttttgttg aacctgacaa
     7441 gaatttgaaa ccagttgttg aatccatgaa tactactggg tggtaatctg gatggatgtt
     7501 ttctttcatg attttttcgc tcctttgccc tgctccattt gctgaaccag agttgatttg
     7561 tcgatttaca acattaacat cttaacatgt ttcagtcaag gttgcaatta tcttttcaga
     7621 tttctggtcg gatttttttt accaaaggag acatcttgaa attctttgaa aaattgctga
     7681 ttgttttttg ttttacgcaa aaagcggatc agttgttccg tatattctaa tgaatctcca
     7741 gtcatatttt ttcgaagttt ccaaatttct tctaattctt cacttggcat caataattct
     7801 tcttttcggg tacctgattt tttgatatcg atggctggga agatccgacg ttcagataat
     7861 tcacgtgaaa gttgtaattc tagatttcca gttcctttga attcttcata gatcacgtca
     7921 tccatacggc ttcctgtatc gactaaagcg gtcgctaaaa tcgtcaaact gccaccttct
     7981 tcgatgtttc ttgctgcccc gaaaaatttc ttaggtttat acaatgcggc tgggtcaatc
     8041 ccgccactca atgtacgtcc gcttggtgga acgactaagt tataggcccg agcaagtcta
     8101 gtaatactat ccatcaagat aacgacatct cgtttatctt cgactaaacg cattgcgcgt
     8161 tccaatacta attcagaaac tcgagtatgg ttttgcggct gcagatcaaa tgtagaagat
     8221 accacgtcgc ctttcacgct tcgttctaga tccgttactt cttccggtcg ttcatcaatc
     8281 agtagaacga ttaattctac ttccggatag ttttcggtga taccatttgc gatttctttt
     8341 aatacagaag ttttccctgc ttttggcggt gcgacgatca atccacgctg accaaaaccg
     8401 attggagaaa agatatcgat cattcgggta gatagtcttt gcggtgttgt ttccagttga
     8461 agctgtcttt gcggataaag aggtgttaag gctggaaaat gcggacgttc ttttgcttct
     8521 tccggatctt ttccattaac gctttccacg tgcatcaaac cataataacg ttccgattct
     8581 ttaggtggac gggcttttcc tgccactttg tccccatttc tcaaactgaa tcgtctgatt
     8641 tgtgaggcag aaatatagat atcttctgca cttggtccat aattgattgg ccgtaaaaaa
     8701 ccgtaaccat cttgaccaac gatatccaat attccttcca tataataaaa tccttgtttc
     8761 tctgcttgtg cacgaatcac agctagagat aattcctttt tattcatctt actgtaataa
     8821 ggaattttaa attctttggc ataactataa acttctttta acgttttgtt ctctagttct
     8881 gccattgtca aataatcgct cattcagctc ccacttcctc tatcatttca attgatgccc
     8941 ctaaggctgt tagtttctcg ataatatgat cataaccgcg taagatataa tctacattgt
     9001 aaatcgtcgt tgtcccttct gccaatagtc cagcaatcac taaacaagca cctgcccgaa
     9061 gatcagaagc cacgacttct gtgccgtgaa gtttatttgg accattcacg atgatcatat
     9121 ttccttctac ggtaatatca gcgcccattc gtgctagttc cggcacatgg ttcacacgtt
     9181 tcgcatagat cgtatcgatg atttctgaag tgcctgtagt catcaatagt aacgcagtaa
     9241 gtggctgctg cagatctgtg gcaaatcctg gataaggata ggtcatgatg tttgcgggtt
     9301 ttaattcttt cgaggggtaa acttcgattt catcttcgct gattttcata tggacaccaa
     9361 tttcctgcaa ttttgctata aagctttcca aatgttcaaa gatcacattt ttcactttga
     9421 taccatttcc tactgcagct gctaatgcta gataggttcc tgcttcgatg cggtcaggaa
     9481 tcatgaaatg ccgacagcca tgtaatgttt cgactccttc gatacggatc acatctgtac
     9541 ccgctcctcg aacttttgcc cccatattat tcagtaaagt tgccacatct atgatttccg
     9601 gttctcgtgc agcgttttca attactgtct gtccttttgc ttttacagca gctaacatca
     9661 cattgatcgt tgctccgact gaaaccacgt ccatgaaaat ccgattgcca cgcaatcctt
     9721 tattttctgt ccgtaaatac atggcaccat gttcatttgt cacttcagca cctagagctt
     9781 caaatccttt gacgtgtagg tcaatcggtc tagggcctaa ataacagcca cctggcaggc
     9841 ctactaccgc ttcgccaaat ttaccaagca gtgttcccat aaaataataa gaagcacgca
     9901 aactattgat ttttccgtgc ggcatcggaa tcgatacgac ttctcgagga tcgatttcta
     9961 gtatgttgtt ggaaaaatgg acagttgcgc ccatgatctc taaaatttca attaatgaat
    10021 gaacatcttg tatgtccggc acaccttcca agatcactgg ggaatcagct aagattgcag
    10081 ctggaatcaa tgcgactgca ctattttttg caccgctgat cgttacttca ccagctaaag
    10141 gtcggtttcc tttgattacg atttttttca tctgtttcca ccttgtttat taatcttttt
    10201 tcatggatat gcttgtattt tatcatagat aaaaaaaaga aacgagcatg gtctgccgtt
    10261 ttaagtaaaa aagaatggag agcgacttca aaagtcgttc tccattccta tatatcgtat
    10321 ctgttatgtg gatgcttacg ctttgttagc tgaaccgaac cagtcgatat gagatttagc
    10381 atcttcaacg attgctgctt tacctggagc taataattta cgagggtcga atcctttacc
    10441 ttctttatct ttaccagctt cgatatattt acgagtagct gcagcaaatg ataattggaa
    10501 ttcagtgtta acatttactt ttgagatacc cattgagata gctttttcga tttgatcttg
    10561 aggaatacct gatccgccat gtaatactaa aggcatgtct ggacctacag catcagcaat
    10621 tgcttgtaag tggtcaaaag ctaatccttt ccagttttct ggatattgac catggatgtt
    10681 accgataccg caagctaagt agtcgatacc tgtagcaacc atttgtttgc attcttcaat
    10741 atcagctaat tcgccgttac cgatgattcc gtcttcttct ccgccgattg aaccaacttc
    10801 acattcaact gagatacctt ttgcatgtgc tttttcaaca acgtctttag ctaatttcaa
    10861 gttttcttca aatggtagat gtgaaccatc gaacattact gaagtatagc ctaattcgat
    10921 acattccaaa gcagcttcgt aatcaccatg gtctaagtgg atagcaactg gaacagtgat
    10981 gttcattgct tcaactaaat cagtgattaa atctttacag attttgtaac cacccatgta
    11041 tttagctgca cccattgatg tttggataag tactggtgct tgttttgctt cagccgcttc
    11101 aaggattgct tgagtccatt ccaagttgtt tgtgttgaat ccgccgacag cgtaaccgcc
    11161 tttacgagca gcttttaaaa attcagctcc tgatactact ggcataataa aattcctcct
    11221 aagttttgta aaactaaatt tgttaagaca attcttaacc aacgacccta ttttaccaaa
    11281 catttcggta gttttctact aaaatcaatg aaaatgaaaa ttttcaagaa gttttttgca
    11341 aaaaataaaa tatccaatag cgctttaatc gaaaaaagtc ttttgctttc tatctttttt
    11401 cctacaaata ataacaaatc agaaaaagag aaaagtgaca agaaaattgc ttatcccctt
    11461 ctcttgctac ttttctcttt ctatcaagtt caaaaattat tttgtttcgt gatctgctaa
    11521 tgatgctccg acaaatgctt tgattaattt ttgcgggcga tttggacgag aaatcaattc
    11581 tgggtggaat tggcatccca caaagaattt tttctctggc agctctacga tttctactaa
    11641 acggttatct ggtgagacac ctgaaaagac tagcccttgt tcttcaaaca attgacgata
    11701 tttgttattg aactcatagc ggtgacggtg acgttcttgc acaacatcgg ctccatcata
    11761 tgcttcagcc gtcttcgttc cttttttgat tttacatggg tataatccaa ggcgtaaagt
    11821 tccacccaaa ttctcgatgt tttcctgatc agccattaaa tcaataatat tgtttgctgt
    11881 atctggattc gtttcagctg atgacgcatc ttctaatcca acgacgttac gtgcaaattc
    11941 gacacaagcc atctgcatac caagacaaat acctaaaaac ggaacgtcat tttcgcgagc
    12001 ataacgaatc gcttcgattt tcccttctac tccgcgatca ccaaatccac caggaaccaa
    12061 gattccatct gcgtctttca aacgttcttc tacattttct ctcgttaatt cttgtgcttt
    12121 gatccaatcg atctcgatgt ctgaattata ggcgaaacca gaatgtttca atgcttcaac
    12181 tactgagata tatgcatctg gtaactcgac atatttaccg acaagcgcaa tccgtacttt
    12241 tttcttcaag ttcaagacac gttcttctaa ttctttccat tctgtcatgt ctgcttctgg
    12301 tgtatctagt tttaaatggt cgcaaacaat ttgatccatt ccttgtgctt gtaaaactaa
    12361 tgggatggag taaagtgtat ctacatctgg cgactcgata actgcttctg gttcgacatc
    12421 acaaaattgt gccaatttgt ttttcacgct ttgagaaaca ggttgctctg tacgtaccac
    12481 caaaatattc ggttggatac ctaaaccacg tagctctttt acactgtgct gcgttggttt
    12541 agttttcatt tctccagcag ctttcaagta aggaatcaat gttgtatgga tatacataac
    12601 attatctgta ccgacatctg ctttcatttg acgaagtgct tcaaggaatg gcaaagattc
    12661 tatatcccct actgttcccc ctacttctgt aatgatcaca tctgaatcag tcattttagc
    12721 tgctcgcatg attttttctt tgatctcatt tgtaatatga ggaataactt gaacagttgc
    12781 tcccaagtat tcgcccttac gttctttacg caaaacttca gaatagattt ttcctgtcgt
    12841 cacgttggag tatttgttca aattgatgtc aataaaacgt tcgtagtggc ccagatccaa
    12901 atctgtttca gcaccatcat ctgttacgaa tacttctccg tgctgatatg ggctcatcgt
    12961 ccccggatcc acgttgatgt atggatcaaa tttttggata gttactttta agccgcggtt
    13021 tttcaataag cgtcctaaag aagctgcaac aatccctttt ccgattgatg aaacgacacc
    13081 gccggtcaca aaaatatatt ttgtcataag ttcaaaaact cctttttaat ttatgtgcag
    13141 gaaaagtctc agacaataaa caaagctccc tattcttcaa taagaatagg gagccgaaat
    13201 ttctgtaaac ttctgaccct ctaaaagggt gcccaaggtg tataatacaa gctgactaag
    13261 ggaaagtcaa gtactcaaat gaatactatc cgcttacaat tttttctttt tcgatatcct
    13321 ttgagaaatt atttcttaag tcctttatga gtgcaaaaaa aatttaaccc acataataag
    13381 cttgatataa acatagctaa cgttaaacct aagcaaatca gaaaatcgtt actgaaaaat
    13441 tttaagtgaa ataatagata aaaaaataaa acaaacatta tgatagataa tatcccacct
    13501 aacaaagaac tactttttcc tacttgcagc aacagtttat atagcttatc gtagaaacaa
    13561 tctttttctt tcacccttat ttacctcctt tacgtaaaaa acgtagtcca cagttctcgg
    13621 atttttggca tatcttttct attaaataat atcaaaaaca aaacaattcc actaattttt
    13681 tcaaagatga cctttttttc aacaaaagtg ccttgtaggg attcattgaa ggtaacgaat
    13741 cacataagta aaaaataagg agatgcgaca aaagtcgtgc ctccttattt ctaaataaac
    13801 ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat ccatcaaaca tgagaagctg
    13861 tttttgaaat tatttcttgt gattcggagt taaatggtag gctcacaacc tctggataaa
    13921 cggtattcaa aagccagttt ctcggtatta agccaaattt atgcaaaaat gtagaaagcc
    13981 attttcacaa aatttttctt aatactcgaa actaaacgtc tttttcaaaa cctcttggta
    14041 aacggtgttc aaaagcttgc atctgcggta ataagttcag ccaattcaaa aacaagaaaa
    14101 gctgtttttg cttggctatt cttattactt gttgcagggc agctttttca caacctctcc
    14161 actaaacggt gttcaatcag ctgaccctcg gtattagctc aaaaaacggc aaaatatgag
    14221 gaactatttt tccgttagtt tctctaatac tcaggtcaaa acgctgattt cacagcctct
    14281 aattcacggt attcctgttt taataaagtt ctagatattg ttctctttcc cactcggaaa
    14341 cagtttgtct gaatgccgcc cattcgagac gttttgcttc aacaaaattt gagaagatat
    14401 gttgtcctaa tgcgtcaatc attacattat ccttacgcaa ttctttgata gcattatgga
    14461 tagttgaagg taagtcctgg atatgtgcag cttctctttc ttcctcatcc attacataaa
    14521 tgttacggtc aacagctgct ggcggtgtga tctgattacg gataccgtct agtcctgctt
    14581 gcaacaatac tgccattgcc aagtatgggt ttgcagatgg atcaactgac cgcaattcca
    14641 aacgtgtgga taaaccgcga gattctggta cacgtactaa tggcgaacga ttacggccac
    14701 tccatgcgac ataaacaggc gcttcataac ctggaacgag acgtttataa gaattgactg
    14761 ttggattgca aacggctgtg taggcacgag catgtttcag caaaccacct aagaaatgat
    14821 aagctgtttc acttagttcc aattcaccgt ctttatcata gaaaacattt ccttcatcat
    14881 tgaacaaaga catattgcaa tgcataccag aaccattgat cccaaataac ggtttcggca
    14941 tgaaagtcgc gtgaagtcca tgcttgcgtg caatcgtttt gacaacgagc ttgaaggttt
    15001 ggatattatc acaagcatct accacatctg catatttaaa gtcaatttca tgctgtcctg
    15061 gcgctacttc atgatgtgaa gcttccactt caaagcctag actttctaat tccaacacga
    15121 tgtcacggcg gcaattttca cctaaatctg ttggtgcaaa atcaaaataa ccacctttat
    15181 cattcaaggt cgttgtgatc ccaccgtctt cgtctaattt aaataagaag aattctggtt
    15241 caggtcctaa attgaaagag gtaaaaccaa ggtcgcgcat atctttcaat gctcgtttca
    15301 aattcccgcg aggatcgccg gcaaatggtg tcccatccgg attatagata tcacaaatta
    15361 aacgagcaac ttttccatga gcactttccc acgggaagat catccaagtg gagagatctg
    15421 gatacaaata catatcgctt tcttcaattc gaacaaatcc ttcaatcgaa gaaccgtcaa
    15481 acatcatttt attttctaat actttgtcga tctggctcac tggaacttct acatttttga
    15541 tcgtacctaa gatgtctgtg aacatcaatc gtaaaaatcg tacgttttct tcctcaatga
    15601 ttcgtttgat ttcttcacct gttatctgtt tctttaccat ggtatccctc ttcctttttt
    15661 aatttattca gtcaaagaat tgtctttgca atccttgcga ctgataatga cctgttttgc
    15721 ttaacccacc ttgcgccaaa atctcatcac gaaaaatttg tcgaacgtca tgatctgtca
    15781 acggcttctt gttttttgct tcttgttttt tcgcctgtgc catttcgtat acacgtttga
    15841 tcccagccat attcaatccc tctgaaagat agtctttaat ctcaagcaac atatcaatat
    15901 cattcagcga atacatacgt cggtttcctt cgcttcgttc cggatgaact aaatcttgtt
    15961 cttcataata gcgaatttgc cgagcagaca aatcagtcag cttcataact gtaccaattg
    16021 gaaatacgga catagatcgg cgcaattcct tttctcccat cagacgtccc ctttcgtttt
    16081 ataagttggc taaagtgtac caattaaaaa aaatattgtc aactgcatat gttaggtttt
    16141 ctaacatgag atctctattt tttataaaat aacaaaaaaa taagaacaca aaaaaggtat
    16201 ctagttgatt ttcgtaccag atacctttta ttttttatta tactgtacta tcctttatta
    16261 gtgtttttat t
//
LOCUS       DADQCX010000066        16153 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.066, whole genome shotgun sequence.
ACCESSION   DADQCX010000066 DADQCX010000000
VERSION     DADQCX010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.066"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..188)
                     /locus_tag="J8R83_001924"
     CDS             complement(<1..188)
                     /locus_tag="J8R83_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAZ9575054.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKNFHFFT"
     gene            882..1268
                     /locus_tag="J8R83_001925"
     CDS             882..1268
                     /locus_tag="J8R83_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9575055.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1362..1553
                     /locus_tag="J8R83_001926"
     CDS             1362..1553
                     /locus_tag="J8R83_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575056.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            2067..2399
                     /locus_tag="J8R83_001927"
     CDS             2067..2399
                     /locus_tag="J8R83_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9575057.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2695..2850
                     /locus_tag="J8R83_001928"
     CDS             2695..2850
                     /locus_tag="J8R83_001928"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAZ9575058.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            3126..4466
                     /locus_tag="J8R83_001929"
                     /pseudo
     CDS             3126..4466
                     /locus_tag="J8R83_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4707..6323)
                     /locus_tag="J8R83_001930"
     CDS             complement(4707..6323)
                     /locus_tag="J8R83_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAZ9575059.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            6441..6659
                     /locus_tag="J8R83_001931"
     CDS             6441..6659
                     /locus_tag="J8R83_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575060.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            6854..7315
                     /locus_tag="J8R83_001932"
     CDS             6854..7315
                     /locus_tag="J8R83_001932"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9575061.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(7508..7747)
                     /locus_tag="J8R83_001933"
     CDS             complement(7508..7747)
                     /locus_tag="J8R83_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575062.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7771..9294)
                     /locus_tag="J8R83_001934"
     CDS             complement(7771..9294)
                     /locus_tag="J8R83_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAZ9575063.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(9312..9434)
                     /locus_tag="J8R83_001935"
     CDS             complement(9312..9434)
                     /locus_tag="J8R83_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAZ9575064.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(9464..10447)
                     /locus_tag="J8R83_001936"
     CDS             complement(9464..10447)
                     /locus_tag="J8R83_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAZ9575065.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(10471..10620)
                     /gene="rpmG"
                     /locus_tag="J8R83_001937"
     CDS             complement(10471..10620)
                     /gene="rpmG"
                     /locus_tag="J8R83_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAZ9575066.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(10641..11018)
                     /locus_tag="J8R83_001938"
     CDS             complement(10641..11018)
                     /locus_tag="J8R83_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575067.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(11050..11229)
                     /gene="rpmF"
                     /locus_tag="J8R83_001939"
     CDS             complement(11050..11229)
                     /gene="rpmF"
                     /locus_tag="J8R83_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAZ9575068.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(11244..11513)
                     /gene="rpsN"
                     /locus_tag="J8R83_001940"
     CDS             complement(11244..11513)
                     /gene="rpsN"
                     /locus_tag="J8R83_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAZ9575069.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(12036..13808)
                     /locus_tag="J8R83_001941"
     CDS             complement(12036..13808)
                     /locus_tag="J8R83_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575070.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13762..15516)
                     /locus_tag="J8R83_001942"
     CDS             complement(13762..15516)
                     /locus_tag="J8R83_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575071.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(15626..>16153)
                     /locus_tag="J8R83_001943"
     CDS             complement(15626..>16153)
                     /locus_tag="J8R83_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAZ9575072.1"
                     /translation="ISLVIYFFSIMVSSIGGAFGHSISPGIFGLLSGIIFVYISYNYP
                     RKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVFGYDRAIPQVASWAL
                     MQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGIWGIISVLVVASLSM
                     IGVLIGRKVLKKYKK"
BASE COUNT         5246 a         3068 c         2443 g         5396 t
ORIGIN      
        1 gtaaagaaat ggaaattttt agttttttta atattatcag ttagtaactt tttataatca
       61 taaaaaaaat aagtagttct atctgagcga tactctttta taatactgaa ttcggaatta
      121 aaaaccacga taggtaactt taaacaaaca tgaagagact ttaataagac ttctttatct
      181 gaaaacactt ttgtttctct ctttcctttc tacatcatta aatagtattt tatacgttat
      241 ctaaaatact attcctctgt caaaataagc taacttactt cattataaaa tatccactta
      301 tcgctttcat gtatattcca ccgtaaaaag tacattttat caccgagaac tcatcatttt
      361 tcatcatgat gaatactatt tacatatatc tagttcaaag acaataatta ttatgatccg
      421 ttattatcta agcactatac agataatagg aatttttcgt ttctaaatat tccaatttgg
      481 gaatccaata aaaattttcg ttcaaatacg tgtctattcg aactcttttc tagttgttaa
      541 ttatgaaggg ggaagaaata aaaaatacaa tctatacacg aataagaata ttatccaaaa
      601 ggaggtttta gaaaagattt attatacgta aaaagctcaa gacattttct tagccataag
      661 gacatgtttg atatttaaga agatatatga attttctttt ctaagtataa agataactat
      721 ccattatcaa ctaaaaaaac atttttgaaa ataaacatca gcagtcctat caatgcatgt
      781 gagcttatag aagttattcg cagcgcagca taattgcatt agcttctttt cgtgtttttt
      841 gcctcttttc cctttaaatc ttaatggagg aggtgtgcaa tatgtcagat aacgacgaac
      901 gcgtaaatgc ccagttgatt cgattctttg aaaaggtcat tttgaacacc gctaatactt
      961 attataaaaa acaagaagaa attcaaaaac atgaacaact tgatcaactc ccaccatatt
     1021 tgtttactaa agatactata aaatttaaac aaccgattaa tgttttaaat gtgactctcc
     1081 ttgttgaaga tataaaatta gcaaaaatcc ttcctttgtt gaaagaacct gaacaaattt
     1141 ttcttatcga aaaatttatc tttgataaaa ctgataaaga aattggaaag gttctgggga
     1201 ttacaagaca gggtgcgaca aatttaaaac atcgacttta caaaaaaatt caaaaaatgc
     1261 tggtttaata tctgcataat aactaatttt gtatgcttct ttgctcgttc tcctccttcc
     1321 caaagaaata gattataagt ccatgggaag aaggtagatt tatgaattct ttaaaagaag
     1381 atttcatttt agcaaaggct ggaaatgaag aagctgttga ggcaattctc aaaagattta
     1441 gctctttgat tcataagcaa tcctggagaa ctggaaaata tgatcaagat tgttatcaag
     1501 aatgtatgct tgcaatatat ctagctatct cgaaattcga aattaaagaa taactcaact
     1561 aagggagtct gtgacataag taaaaagata gtttcaaatt tcgaacaata aatttgaaac
     1621 tatcttcttt ataattataa agtatcgatt ttacagcgtt ctataatgat tcatagaatc
     1681 taaaacgaat gattttaatt atcaacgttt tttaattcgt ttttagctta aaaataactt
     1741 ttgtcacagt ctcactccta aaattacttt atttacgtat gaagtgggca ggaggtcgaa
     1801 tccagaactg ggctatggta cttcaacgag gacttctcct ctagaattga aaagcatgcg
     1861 atttaccttc cgtaacgacg gtagatttat tcaactatgt gtccaatcaa aatttgtctg
     1921 atttcaaaaa tagtcaagag aattttggtt gttaaaaact cttatctatc aacttccaca
     1981 gtttagttga caaaccctga tactaagttg ggctatgata cacttttctt gactatcagt
     2041 tacgttaccg gaaggaatga actctattga gaaaaacata tgatcgtaaa tttaaactaa
     2101 agatttcaca ggatatcctt gagaaaaaag taactaccaa gaaaattgct gaagaataca
     2161 atatctctcg tccaacaatt tcccgatggg tttcagaata tcgtcgatac gggaaaaatg
     2221 cttttgctgg acaaggaaaa agattacctg ataaagcaga tttctacatt cttgaacagg
     2281 aaaataaacg actaaaagag gaagacgagt gttctacgaa cacaaagatc gatacggatc
     2341 tccagggatc actcaaaaac tttacgatga aggaatcgaa atcaataaac gtgttgtagc
     2401 tgttcttatg cgtgaaatga atttatgcac aagaggattt catcgacgca aatcttctca
     2461 tggtagagaa aaaacaatca aagaaatggt aaaaaaatgt tgaatcgata atttgaacag
     2521 aaccaaattg atgctgtttg ggtgatggat attacttaca ttccatgtaa tgacggtcgc
     2581 ctctatttgt ccacctatat tgacttagca actcgtattc tacgttacta tatggtagat
     2641 tcacacatga aaaaagagat tgtcgtccgt ccattacaaa tttattaagg agaattgcct
     2701 acggtaattc attccgatag aggtagccag catcggtctt ttatttatca agagctgttg
     2761 aacgaccacc acatcacaca ttcagtgagc caaactggga ctcctgttga caatgcagta
     2821 attgaagcgt ttcatcgatc aatcaaatga gaattaatcg actccaacaa atataaaagt
     2881 aaaatagaga tgaaggtgtt aatccaagat tatttagaag actactaccc aaacaaaaga
     2941 atccatacaa aatttatgat gactccttga caatttgaag cgaagaaaat aagggatcta
     3001 taatatctag tgttggtgac gccttctgtt gccaatactt tttctttttt ctaataaacg
     3061 caaacagaca ccttaaaatc ctttagaata aagtcgacga aaaccattca aaggagtgtt
     3121 tcaagatgtc ctattcagag tttaccaaag agttactaga tattctagac ctaaatctta
     3181 tctttcatga agatgccttt cgcaaagagc gaatcaatga cgaaacatgt tttgtttttg
     3241 atggcacatt gacctatcaa ccggaggaat gctttcatcg ccactatcaa aatgaacaaa
     3301 cgatcattaa atagggctgg aaaaaagtat ccatcttatt gaatgatgtc agtaactaca
     3361 agaccattct gcggattaac aaacagcgct tcaaatgtaa acactgtgga aagacttttt
     3421 tagcagaaga ttcagttagt gatcgtcgct gctccattgc tcgcagagtc aaacaagcca
     3481 ttcttgagct attaagcgaa cctctttcta tgtctttgat cgcacgtatg aagcacattt
     3541 ctccgaccac tgtcattcga atacttcgca gccttcggcc taaaaccatt tctttgagcc
     3601 agctgttacc agaagtggtg tgtttcgatg aattcaaatc agtgaaaaat gtctcgggag
     3661 ccatgagctt tgtcatgatg gacggcaaga cccatcaact gattgatatt gtggaaaatc
     3721 ggcaactcaa tcctttacgc gactatttct tgcgctaccc tataaaagtc cgtgaacaag
     3781 tgcgtctagt ggtttcagat ttctatacac cctatcgcac attggtgaaa gagtgttttc
     3841 cgaatgcccg aatcgtcgcc gatcgctttc atattagcca acacattggt cgggctttta
     3901 ccaaccaccg aattcaagta atgaagacct ttaaaaaagg ggatcgtcgg tcgaagcact
     3961 taaagaaata ctggaaacta cttcaaaaga atgcgtggga attgaaaggt cagcatcgct
     4021 actggcgtcc gtcatttcga gatcatctga cagaagcaga gatagtcgat cggctattat
     4081 cttatgatga ttccttaaag cgaggctacg aagtctacca ggattttctt tccgttatca
     4141 gaagacaaga tgttcctgaa ttcgtcgcgc tcctaaaaga agactacaag gagttgccag
     4201 agcactacca accagtgttc acgaccttca agaaatacca aacagaaatc aaacgagcgt
     4261 tgcgcgttcc ctattccaac ggccctatag aatgtttgaa taaccatatc aaagtactaa
     4321 aacgaattgc ctatggctat agaaactttc aaaactaccg agaacgaatc tttttatatc
     4381 gaggaaaata ttttaagaaa actaagaata ctacccaact gactaaagcc agaacaacaa
     4441 cacggctaga caagatagct gtctagccgt gtgagtatct cgattattct attgaatttc
     4501 ttcaccaaca ctcattgacg aagagccaaa ataagtaatc taaccgactg ttaactaaac
     4561 cattgcaggt cccgttaaag atacttgtgc ctgttgtcac cgcttctttt tcttgtccac
     4621 aagcgcttaa cacacttaat aaagcccctg ctattattaa taataatatc tttttcttat
     4681 taaaaacctc ctcatctatt tccagattag taaatgtagt aatctgtgct ttcttttttc
     4741 tcaatactaa taactaactt atggggtaaa caaatactcg tttgaccggg ttttgagatc
     4801 catccagttc taaccgcgat ttgatcagga ctattatctt ctttaactcg aattcttcca
     4861 tctttaatct caacaatatt atattgtccc ttcgcaggat gataattcac gagtttatga
     4921 ttgatcttat ccaaatcgaa gcgatccatt tccttgccat caattcgaac gatggcatat
     4981 ttgatagcat cttcagttgt ttcattctcc ttttctatag agaatacaaa taagggaata
     5041 aaagaggtaa taatcaaaat gccaataatt atgacatcgc ctatcttgac accagctttt
     5101 cttaaaaatt tcattaacga tatctggcta aacatattag actttttcca tggaaatggt
     5161 gaaatttttc ggaaattatc tgcattaaga gaatcagtta aacaaccctc aagttgttcc
     5221 ttaatacatt gttgatccat cttcatacca ataaaaacta gtttattaat gcgttcacca
     5281 aacaacggat gccaggcttc cttcaattcg ggattttttt gtataatcat ttgacactca
     5341 attttaggta aactagctac ccaataattt aatgattcaa tacttttata gctacccgat
     5401 gtttcaaaga tcgtcgaaaa atcactatgt tgggcaaacc aaagaaaccc ttttgctctt
     5461 gtaatattgc caggaaaatt tttatccgta agatgggcaa atttttgtgc gtcaaggagt
     5521 aaccgatttc gatagataaa acttgagata ccatattctt ctgtttcagg aatatgattt
     5581 tgatagccaa gctctaactc tttgaaccag cccactgaat aggaagtctc atctatatta
     5641 aaaagatttg tatttagaat tttcgataag tctacttcac ctttaattgt cctaattatt
     5701 ttggcattgg actgtaactt agcaattaga ccgttaattt tgtaaatcgt cttggttgac
     5761 actaagtcac tattatttaa aagtaatatg ttacaacact cgaattgatc aattaacaag
     5821 ccacgaatat cctgttcttc ttcaactaca ttaccttcag cttttctttc ctgaatcttt
     5881 tcacccgttt cgaaattatc ccaaaaacgt tttacatcca ctactataat aatggcacca
     5941 atctctaatc gttgggtcaa atcaatgtct aaagggtttt tagctaatat aattgcttga
     6001 ataattggaa ttggtttgct gattcctgaa gcttcaataa caatttgatt caagtcagaa
     6061 aattgcacta attgatctag ttcaacaatc aaatcttcgc gtaatgtaca acaaatgcat
     6121 ccattcggca tcgaaacaag tttttctcca gttcttttaa aacctttctt gtcgactaat
     6181 accccatcaa catttacttc ccctatgtca tttacaatga cagcaatttc ctttccgtga
     6241 tcaccgtaca gaatatgatt tagaagtatc gtttttcctg aaccaagata gccagttaag
     6301 attgtaatag gtattttttt catagggaac ctctttctat accttgaatt tacactttaa
     6361 gtgcaacaca taaaaatgag tcataatcga tatccaacta gtataagttt gtcgagaaca
     6421 ctcctagaag gaaaataatt atgagccagt atcgtcatct tactatactc gaacgagaaa
     6481 gaatctttct gcttcacgaa gaaggatttt ctattagtat aattggcaac gacattcagc
     6541 atagcccgtt tactatttta catgaactga gaagaaacaa gaaaaaaact attcaccttc
     6601 caaagcggaa aaaaattatg cttatcgaag aaaaaaatgc ggacgttatc acattctaaa
     6661 tgatccgtga gtttggtcaa ttgttcgtca tttatttgtc gattttcagt ggtcgccaga
     6721 ggaaatctcg aatcgtttga agcatgaaca tatggacttt tcaattagtt ttatcacgat
     6781 ctaacgtgca atttgcaatg atcttttcga tacagaaccc ctctcacacg gcaataaagg
     6841 cctgatccgt tcattgcacc atcgaggaaa aacaagacat acaaaaaatc atgtcgagtc
     6901 tcgtggaaag atttgcctta ctcattcgat ccatggccgt ccaaaatccg cagatgatag
     6961 aagtgatttt ggtcattgga aagccgatat tgtagctggc aaaactggtg gtacttgttt
     7021 agtgactttg acagacagaa aatcatgctt ccttttagca ggaaagaagg tccccagaaa
     7081 gaaagccgct tatgtgagcg agaaaatgat tgaactttta agcagtattc caaatgaggc
     7141 ggtcaaaacg atcactccag atagaggaaa agaattctcc aatcatttcg cagttacaga
     7201 agcattgaat aatatgccct tttattttcc agatcctcat gcccttggca acaatgaaca
     7261 aattaaaata cgaatagact cattcgagaa tacttgccaa aatcgaaaga gatagctacg
     7321 gtagataact caacgataaa tcagatgatt gaaaaactga ataacagacc tagaaagtgt
     7381 ttagattgga gaacacctta tgaagtcttc tttgataaag tgttgcgctt gatttgacaa
     7441 ttcaagacat aataaaaagc agatcaaatc caaataaggg aaaaatgatc tactctggta
     7501 ttatcaatta attggccaag ctattatgcc gttttgctaa acgtctactt cttccagtat
     7561 tgaccttgat aaaacaacaa tcaggatccc gttttaatac tctatgaact gtgtcaatac
     7621 taacatgtaa agttgcagca atatcagcta atgtactccc atttaatctc atttgctttg
     7681 caaatcgata acgccgataa gcatcaatat tcttggaatc catagacaat aatacttttc
     7741 ttaccatgta tttcctccaa aaattgaatt ttaatgagcc atcatttctt gagcaatttc
     7801 atgtttagac aatgaagctg gatagaaagt aggccaatta tgcaattcat tatagagttt
     7861 ttcttgactt tctccaccaa agaaaatatg gaaatgctct gccttacttg gtgcaattcc
     7921 atgatcacta aattgaatat atttaaaacg accagcacct gcatcatcag tttcaaaatt
     7981 aaaacgaaca ccacggtttc ctttttcata attcaaaatt ttgtatccaa catatttgta
     8041 tgtgtattga tgatgttcac cgttgactac aaaatcaatg gtgttgtctt taatgttgat
     8101 agtatcaata tctgtcttat agccagtagt ataataatct ttgtactcgg cagctgtcat
     8161 gtctttattg atttttgctt tgtaatcgaa aacttcatcc aaaattccat cttttaacaa
     8221 cggataaaca gattgccatt cgcctgtata atcactcaat tcgcgatcct tcacatcggc
     8281 atctttaaag tacccattag caactgtctt ttcatccttc gcttcttttt ctggaactac
     8341 ctcttcacca gcaaccatag ttgttttttc taacgctttt agattgtctt ccattactga
     8401 aacataatct tcaccattat ccatttgttc ttttgtaaga ctttcaagag gattcagtac
     8461 ttccaatttt atcccagctt cgttggccaa agtttttgca attttatcat tagcattctt
     8521 ttcaaagtaa atataattga tcttattttt tttaacatac tcttttaatt cagctaatcg
     8581 accagaagat ggctcttctt caggacttag tccagcaata ggaacttgtt tcaatccata
     8641 atccaaagct aaatatccaa aggctgcgtg ttgcgtcaca aaactttttt gtttcgcttc
     8701 tttaagacta gtggtatagt cagcatccaa ccgtttcagt ttagtcaaat acttttcagc
     8761 atttgtctca aatacttttg cttttttcgg atacaattta actaactgat ccttgatatt
     8821 tgaaacttcc ttaattgcca ttttgggtga aacccacgta tgaggatcta gttcatgatg
     8881 gtgatcttct tctccgtgat catgatcttc ttcttcacta cctggcaata aaatcatgtc
     8941 ttttgttcct tctactacat taggcccagc tttcttccaa ctttctttag cttttggtac
     9001 ccatgattcc atgttttcgt tatgatatac aaaaacatca gcatcatgag cttttgccat
     9061 atccttagct gagggctcat agtcatgagg ttctgatccc gctggaacca ttaaatccac
     9121 gttcgcttca tcgccgacga tgtttttggt gaaatcatac attggataga atgttgttac
     9181 aatttctaat tttccatctt tatcattcga tacttttgca tcattagtgc tggagcaagc
     9241 tcccaataat cctagagctg ctatcccaat aagtcctaca ctgattttct tcattctttt
     9301 tccttcctta attatgctaa tttcttcatt ttatttcgtt tatgttcttt gataattttt
     9361 aatgcccttt ttctagtttt aatattcggg cttttaagtc gtcgatatgc actagatata
     9421 tccgttttct ccattagaaa ttacccccaa tcactactta tcattatttg ctttccgcca
     9481 gtaatttatc aaaactctgt ttgatccttt cttcatccaa catttttccg attagaataa
     9541 tagtggtttg gtctttttgt cgagtggtgt attgaaaatt aacctgttcg tttacctctt
     9601 gcatggcaac tataaaatcc tgctcttgta aagcaatcaa tcctttaaaa cgatacaggc
     9661 tcccttggtt ggttaaaatc agccagtcaa tccattggag taaaaaatct ttttttatgt
     9721 cttgatctga agttaagaga attgatttaa actcatgtac ttgatggtgt tgatgatagt
     9781 atttgccatt atagtgattt tctgatgaat cactttcaaa aactaaggga tgattaaatt
     9841 ttttcaaatt ataaaaatcc tttttttgaa tcgtttcact atgtgtgaac attcgaatat
     9901 cggataaagg gttaatactt ttgatttctc tctgtaattt ttttagtgca gataaattca
     9961 agttttgttt tctagacaca aaaatgcgat ctgccatgac aagttgctta agggcttgtg
    10021 gttctctttc aataagttca aaactgtcac tatcaataac agtcaataaa ctatcgatat
    10081 atactcttcc tcttagttga ggcgctgtta aaagtgtttg aatgattggt tggggatctg
    10141 ctatacctgt agtttcaatg atgatttgtg aaattggttg ttgatgttct tctattgttt
    10201 ccagtaaaga aatcaatatt gctaataaat cactgcgaag actgcaacac atacatccat
    10261 tatttagttg taacacccgt tcctcgctat gaactaataa tttgtgatca atcccaactt
    10321 caccaaactc attttcaatt ataataattt cttccctggg gtagggtgag acttgcaagg
    10381 cttgattgat tagcgttgtt tttccagccc ctaaaaaccc agaaacgatt gtaactggta
    10441 tgcccatttt gtcacctttt taccacttag ctatttcact tctttaaaaa ttgcccgtct
    10501 gcgcaatttt ggcgaatact tttttaattc taaccgttca gggttattcc gtttattttt
    10561 gctggtgaga tacagacgtt ctccagtttc gacacattcc aaaataatat tttgacgcat
    10621 aaatcttcct ccttcaatac ttatcgatct tcaagatatg cttgaatttg ttgtgcatct
    10681 tcaaaagtta actcgccaga ttccaattgt gaaactaaat tttctttcat atcaacaggt
    10741 atctcccaat aaccatcgat acattgaaat aactcctcgt catactcttc aaaaattgga
    10801 tagattctta aaaaatcatc aaatgataag ccttggtcct catagtaatc tttgactaat
    10861 ccattttcaa ttgcctgttg ggtcggtaaa cccgtttcag taataattcc tctctctacc
    10921 atcgaacgat aaaaagtgca tttatctagc gattgctggg tcgtttcaag ataatacttt
    10981 aatccttctt caactaaagg tgggtaaata atttccattt tgattccctc ctaaaagtta
    11041 tatattaaac tattttgaag ctcctttaat tactttcttt ccattatagt acccttttaa
    11101 agatacatga tggctacgtc tataatcacc attcgcttcg tcaaatgaaa tttctggttt
    11161 tactacagtt tgatgagttc ttcttaaccg tttcttcgcc ttagatgttt ttcttgctgg
    11221 tactgccatg atatttcctc cttttaccaa cttgcttttt ttactccagg aatcaaccct
    11281 tgatgggcaa gttctctaaa cttaatacgg gacataccga actttcgcat ataccctctt
    11341 ggacgaccat ccgtctgatc acgaagcctc agacgattcg gatttgaatc tcttggcaat
    11401 ttagcgagag cggtgcgatc tcctgcggct tttaattcct gacgtttatc tgcatacttt
    11461 tcaatcatcg ccatttgttt ctttgcttta gcaattttcg acttttttgc catatacctt
    11521 tatactcctt ttattttgat ttagacacct caaatcgtaa tcgttacgtt ttgacactga
    11581 tactttacca acaagagttg ctcttgtcaa caataaataa catgaaataa aactcatatg
    11641 aatagataac tatttgaaaa cgaatttatc ggtacataga gataatcaaa tcatttaaaa
    11701 gaatatgcag tttaggctct gaaaaataag aattcacttt tattagtcca atcaaacaca
    11761 aataccgttt taagtagctt ttcctctact taaaacggca atatgaaaga aactataact
    11821 ttttattcaa tcttttatgt ttaactggtt tatcgccaat tttttaaaac tttgattatt
    11881 ccttatatta taagaataga cattaagtga actaattcaa tcatactgat tctttcgtgt
    11941 attcaaaatt agatgctgtt taataaaatt attctttttg aaaaagaatt ataactatat
    12001 cccaaaaatt gtaggttaat ttaaagccta tttcatcatc gtgattgagc ttctttttca
    12061 tagacgaatt tctcagatag tttagttttc tttatgagat ttttgtatat ttctgacctt
    12121 cgatacaact cattatgagt accttgatca actagttttc cttgatccat cactacaatt
    12181 ttatttacct tttcaataga cttcaagcga tgcgatataa ttagtactgt cttatcttgt
    12241 attaaacgat ttaaactttc ctgaatacgt ttttcatttt ccgcatctaa actggcagta
    12301 atttcatcta aaattaaaat tggcgcattt ttcaaaaaag cccgtgctat ggataggcgt
    12361 tgtcgctctc ctccagaaag tgaacttccg ttttctccga ccaatgtatg ataaccgtca
    12421 ggtagttttt caataaagtc ttcgcagtta gctaaacgag ctgctttttt cacttcctca
    12481 tctgacgctt gactatttcc aatacgtata ttttccaaaa tacttgtatt aaacaaagtt
    12541 acctcttgaa aaacaatagc gattttgcta aacaaagaag ctggagatac acgtttaata
    12601 tcatacccat caattaaaat acagccttca tcataatcat acagtctaga cactaatttc
    12661 aagatactag ttttcccgga accactagca cctactaacg cagtcacttc tccttgttta
    12721 gccgtaaaag agatatgatc taaaattggg gtattgttat catatgagaa agagacatct
    12781 cgcaactcaa tgtcaaaaga tttcagagga ctatctgatc cctcttggat actggtttcc
    12841 ttcatagctc taattcgctg tattttagga gctaaataaa atatttcaag cactgcttct
    12901 ttcatagaat cgaaggaatc ctttattttt attgcggcta gtaagtaacc aacgacgtag
    12961 agtatagtca cttcacccgt taacagtaag tgaacaccta ctagaatgac tactgctaaa
    13021 ctaacatatg agaaaataga ggataaggcc atgactgaaa aagtacttaa ttctaccttt
    13081 aaatgaatcc tttcactctc ttccattttt ttgaaaagtc tgtcttgaac ttttttagat
    13141 agattaaagc tattaatctc ttgctgcaat tctatagttt cttgaaattc ttccgagttt
    13201 tctctcaaag tatcgtaata tttagtattg gctttcgttt gggatttctt tgataacaag
    13261 attaagacaa aactaaataa cgttggcaaa ataacagcta atcccatttt gacattacca
    13321 accaaaagca tcactgaaat aaaagggaaa aacagagcca taccgccggc tttaggtatt
    13381 gcatgactca tcgcatgctc aataccttca acgtcagaca tgatagtttg agataaatct
    13441 gataaattat gttttgaaaa ataggataat ggtaaatttg acaaatcgtc tgcaatttgc
    13501 actcttaaat gcgcactttc tttataagta ctattatata agttttcata ctccctatct
    13561 aacaaccaat acatgaaaag caaagtaaca aacgatacgg caaaataaag ccaacggggc
    13621 tttgtatttt ctaaaactaa ttcgtctatc agcatcatta taatgaatgc tggtaccata
    13681 ttaatgcagt atacaaaaaa actagaaata gaagctttag ttaaagcttc tgcgccctga
    13741 tcacttaaag caaatttgtt tttataaaaa cttttcattg tcaagcctcc aatcatttgc
    13801 attctcataa ttagtgacca attgtttata cacttgatgt ttagccatta attcattatg
    13861 atttccacgt tctactattt tcccttctga caagacaaga atttcatcta cagatttaat
    13921 gctggataat cgatgagcta tcataataac tgttttttct ttcatcagat gttgaaaagc
    13981 cttttgtagt tcatactcat tatctggatc aatagatgca ctggcttcat ccataataac
    14041 aatctttgca tcttttaaaa ttgctctggc aatagctata cgttgttttt ctcctcctga
    14101 cagataaact cctttactac caattaaggt atgctctctt tcgggaaatt tttctaaaat
    14161 cgattcgcaa ccggctaatc ttagcgcgtc aaatacttta cttgctggcg cttgaggatt
    14221 tgctatagaa acgttatcgt aaatactctg attgaatagt ttcgtatctt gaaagacaaa
    14281 agcaattgtg ttaataattg tgtcttttga atagtgattt aaaggcttac caccaatttt
    14341 aatctgtccc ttatccacat tgtagaaacc tgaaattagt ttagctatcg tactctttcc
    14401 gcttcctgat tttcctacta atgcataaat tcttttttgt tctaaaacta agttgaaatt
    14461 ttctaaaaca cactcttctt tgtatgaaaa gctgacattt tcaaatgcaa tgtcacaatt
    14521 tttaatctgt gtctcgttcc catattttag ttggtcttgc ttcatttcta aataaaggga
    14581 gtctagtgtt tcgactgcat atcttgcttc aaacaagtgc atacttacat acattattct
    14641 catgaaagaa acaaaaataa ttccacttaa aaaaaacaac atcaacaagt caacagctaa
    14701 tatcttggga gtggtaagag aagttataaa aaaggttata ggaactatca aaatgcaaac
    14761 tatgccaaaa aatagccatt gaaaaagaac aaaaggtgtt ttcccactca aagaatactt
    14821 atatgcaaac ttagcataat cgttaattgc tttattcaag gctttaaatg atgttacttt
    14881 agcaccaaat atctttataa cttgaattcc gcggatatat tctaccgttt cagagcttaa
    14941 cacatctaac gattcttgat atttttgaat aaaatttgta ttctctgtca ttttctttaa
    15001 caagaataca ccaattacta acatggcgat tagaaccaat ccaattttaa agttaatgaa
    15061 aaagcctaag gcaactgata aaacaggtgt tactatggct tgagcactat ctggaatcaa
    15121 gtgagcaatt gccatatgtg ttttagccgc gttgtcatca attgtctttc gaatatatcc
    15181 cgaagaattt aaatcaaaaa aacgaaaact tgcttctgtt aaaccgctaa ttcccttttt
    15241 tctcaaatta gtctctaagc gaaacccaag gatatgagaa aataagccag aaaaaatata
    15301 aaataaagct cctaaagtta accaagcaac agtttgaacc gcataactct tagctaaata
    15361 ttcatctcct acaataatta gagactgaag aaatttgtaa atactgtaat atccatagac
    15421 tgttaatacg acagaaaaat cagaaaataa agtggctaac catccgtagt atttcatttt
    15481 agggacataa ctaaataatt ttttgtatac tttcattttt tcctcccccg cattcaattt
    15541 cttctcttat tcgtttacaa ctgttaatgc tttccgtaat agcgtaaatt agagatgtac
    15601 aaacagataa aaggtaaact acgttctatt ttttgtattt ttttaagact tttcttccaa
    15661 tcaatacacc aatcatagat aaacttgcta caactaacac tgaaatgatt ccccatatac
    15721 ctaccgcata gtggatcatt gcatccattg ttgcagcaga ttgtccttta tctatccaat
    15781 cttgacgaaa acgatctgta aagaaccata taggaatcca ctgtccggca gcactgccta
    15841 attgcattag agcccaagac gcaacttgag gaattgctcg atcatatcca aatacagata
    15901 gaataatatc agctaagatc gccatactaa tcgaactgat aaaccaaggt aagtacgccc
    15961 cgcccattaa cgtaaaaaat aacaataaaa caattgtgta aatagtaaaa attccttttc
    16021 tagggtagtt atagctaata taaacaaata tgattccaga taataatcca aaaatcccgg
    16081 gggatatgct gtgaccaaac gccccaccaa tactactaac cattattgaa aaaaagtaaa
    16141 ttactaggga aat
//
LOCUS       DADQCX010000067        15957 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.067, whole genome shotgun sequence.
ACCESSION   DADQCX010000067 DADQCX010000000
VERSION     DADQCX010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.067"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(33..908)
                     /locus_tag="J8R83_001944"
     CDS             complement(33..908)
                     /locus_tag="J8R83_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9575073.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            1056..1388
                     /locus_tag="J8R83_001945"
     CDS             1056..1388
                     /locus_tag="J8R83_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAZ9575074.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1500..2708
                     /locus_tag="J8R83_001946"
     CDS             1500..2708
                     /locus_tag="J8R83_001946"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAZ9575075.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2862..3317
                     /locus_tag="J8R83_001947"
     CDS             2862..3317
                     /locus_tag="J8R83_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575076.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3679..3954
                     /locus_tag="J8R83_001948"
     CDS             3679..3954
                     /locus_tag="J8R83_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575077.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3967..6045
                     /locus_tag="J8R83_001949"
     CDS             3967..6045
                     /locus_tag="J8R83_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAZ9575078.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6205..8091
                     /locus_tag="J8R83_001950"
     CDS             6205..8091
                     /locus_tag="J8R83_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9575079.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            8103..9050
                     /locus_tag="J8R83_001951"
     CDS             8103..9050
                     /locus_tag="J8R83_001951"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAZ9575080.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            9070..9597
                     /locus_tag="J8R83_001952"
     CDS             9070..9597
                     /locus_tag="J8R83_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9575081.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9660..10313)
                     /locus_tag="J8R83_001953"
     CDS             complement(9660..10313)
                     /locus_tag="J8R83_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAZ9575082.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10445..11287
                     /locus_tag="J8R83_001954"
     CDS             10445..11287
                     /locus_tag="J8R83_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9575083.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11445..12341
                     /locus_tag="J8R83_001955"
     CDS             11445..12341
                     /locus_tag="J8R83_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9575084.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12344..13057
                     /locus_tag="J8R83_001956"
     CDS             12344..13057
                     /locus_tag="J8R83_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAZ9575085.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            13077..13595
                     /gene="msrA"
                     /locus_tag="J8R83_001957"
     CDS             13077..13595
                     /gene="msrA"
                     /locus_tag="J8R83_001957"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9575086.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13592..13819
                     /locus_tag="J8R83_001958"
     CDS             13592..13819
                     /locus_tag="J8R83_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAZ9575087.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13971..14522
                     /gene="lepB"
                     /locus_tag="J8R83_001959"
     CDS             13971..14522
                     /gene="lepB"
                     /locus_tag="J8R83_001959"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9575088.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14605..15147)
                     /locus_tag="J8R83_001960"
     CDS             complement(14605..15147)
                     /locus_tag="J8R83_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAZ9575089.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15384..15782)
                     /locus_tag="J8R83_001961"
     CDS             complement(15384..15782)
                     /locus_tag="J8R83_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAZ9575090.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         5524 a         2747 c         3212 g         4474 t
ORIGIN      
        1 tctttcctca tagcctatct ttgtcttttt tcttatagtt ttttcagtaa tcttgtctgt
       61 ggcttcaaat aagtaaagcc ttgcccttcc acttcatgca cattgatgat tgaaaggaaa
      121 gctttttcgt caatctcgtg gacgatcctc ttagcttcag ttaattcact agagctaacg
      181 accatataga tgattttttt tgaattacca gagaatgcgc cttctccaga aaggaaagtc
      241 acacctcttt gcagaccggt catcagtagt ggtgcaatct cttcgctttt gttggagacg
      301 acaagtagac cttttgcaga atatccgcca tctaagatcg aatcaatcac acgactgaaa
      361 acatacgaaa caatcaacgt atacatcata cgtttcaagt cgatataggt taatgaagca
      421 agtaagacga tgatatcaaa tgccaatagg gaacgcccca tagtgatgcc gtaattttgt
      481 tctaaaatcc gagcgataat atcactgccg cctgttgttc cacccatgcg gtagacgatc
      541 ccgcttccta cacctgcaac taaacccgca agtagagaaa cgatcagtag atcatgctgt
      601 aaattgattt ctagtggaac cctttgccag atccataaaa agaatgacaa agaaagtgta
      661 cctagaacag tataggccaa ggaacgttta ccgaggatct ttcctcctag taaaatcaat
      721 gggatgttga ttaataaagt cgtataagct ggatcaatac caaataaagc tcttaagatc
      781 aaggtgatcc ctgagactcc cccttctgct aaatgattag cgatgttcaa gtaaacaaga
      841 ccaaatgcat aaatacttgt tcctataatg ataaaaagaa cttcttttac tgtttttcgt
      901 ttgaccatat gaattccagc tttcaattat gtattttcac agaatttcca tttagaaatt
      961 ccttcctaaa tgtagcatgg aaattcgatt ttctcaattg ctcttatcta ggatttgcgt
     1021 taaagttttg gtaagatagt tttggaggga aaaagatgga taaaaagcgt tctttataca
     1081 gtatgcagca ggaagtggat gaatatatcc agcaattcaa ggtggggtat ttctctccat
     1141 tagctcagat ggctcgatta actgaagaag taggtgaatt ggcaagagaa gtcaaccaca
     1201 cttatggaga aaaaagcaaa aaggcttctg aaccagttaa ctcggtagca gaagaacttg
     1261 gtgatgtttt attcgttacg atgatcatgg ctaattcatt gaatatcgac ttaactgaag
     1321 tttttgaaaa aaacatggaa aaattcaatc aaagagacca taatcgcttt gagcgtaagg
     1381 acgagtaaac aagatgaagt ggtcctggcc ttgaagactc tgaaacggac ttgtcaaaca
     1441 gtcaccatgc aactgagtct ttatctcagg acaagaaaca cgcaggaaag gttggaaaaa
     1501 tgaaattaaa acaattacct ctggaatacc aaaaggcaat tccagttctg aaaaaattag
     1561 agaatgcagg atatgaagct tattttgtag gtggaagtgt tcgtgatatc ttgctgaacc
     1621 agccaatcca tgatgtggat atcgcaacaa gcgcatttcc agaagaaatc aaacagcttt
     1681 ttccaaaaac gatagatatt gggatcgaac atggaactgt gttggtatta gaaaatgatg
     1741 aacaatatga gatcaccaca tttcggacgg aatcaactta tcaggactac cgtagaccag
     1801 atcatgtcga attcgttcgt tcgttggcag aagatttgaa aagaagagat tttacgatca
     1861 atgcgtttgc tttgaaagaa gatggagaaa tcatcgattt gttcgatggt ctgcaagatc
     1921 tagaagaaca gatcttgcga gctgtaggca atcctcatga gcggttccat gaagatgcct
     1981 tacgaatgat gcgcgggttg cgttttgtca gtcaactagg gttcaaatta gaggaagaaa
     2041 ccttctacgc catcaaagaa aaccacgagc tattaggtaa aatatctgta gaacgtataa
     2101 atgtggaatt catcaagatg ctcttgggaa atgaacgggc cgcgggaatc catgcattta
     2161 ttgaaacaga gtgctacatt tgctgtcccg gtttgaaaga agaaggcgaa gcacttttac
     2221 gttttgctga attaccatcc gtcccattga aagaagagag ccaagcatgg gcattattga
     2281 tcagccaact ggatctaaaa gaaaatgaga ttcgttcctt tttgaaatcg tggaagtgtt
     2341 ctaaccaaat gattaaagac gttcaagcac ttgtccaagg actacgacaa cgagaaactg
     2401 gagctttgga accattcgaa ttgtacttct taggcaaaaa acatgcactg caagtagaag
     2461 aattgatgat ctattttgac gaaacacctc agatggatgc cgtaggagaa tcctatgatc
     2521 gtttacctat caagtcatta agcgaattag cagtagatgg taaaatcttg ctagaagaaa
     2581 ctggaaaaaa acctggtaag tgggttagtg aagctttgca attagctgaa aaagccgtcg
     2641 tagaacaaag aataaaaaat gataaaaaac aggttttgga ttttttatcg aaagaaaaat
     2701 tgatttaaaa aacactagac tgtatctgct cagctttgtt ggctacttaa agtgggcaga
     2761 tacgtcatta gaagaaaaaa cataagatgt gaccacttac ataaatttgt gctaaactga
     2821 ggtagtacaa gaataaatta catcataaag gagtcttttt aatgagtaaa gaaatgacag
     2881 cgctaaaatt ttattttaga aatggagaaa cctggacgat caaccgccgt catatcggcg
     2941 atctttggat caaacaaatc acaacaagtt ttggacgaat caatggcagt gaatttgttg
     3001 aaatccatcc gtgtgctgga tttaaaatcg aaatcttcca tgaaggggac gcagttgcga
     3061 cacatgatat caacctaggc ggactggaaa tgggcatgtt taatcgcgca ttgaaatacg
     3121 aagatatcga gcgaatggaa atcctttacc gaaatggcac acctgatctt gtgtacttcc
     3181 catatctaga taaaggaaca gaaggattag acaatcaata tcaatcaaca aaaatcagcg
     3241 aaaaaacagg taacttgtat atcgtgatca atccagatca acgtgtagaa gatgtatacg
     3301 gggaattttt cgaataaatc gatttttacg caaaaatgag gctgtgaaag agatgtgtct
     3361 tattactact gataggctgt ctcttccaca ccgtttattc agaataaggg actgtgacaa
     3421 gatttttgtc gcagccccat ttttttgttg tgataaaaga acaagaaagg caggaatggg
     3481 aaagtaaaca tccttttgtc agaaactttt atctttctta agttttactt gatatctgat
     3541 actatttgga atagaatgag gcgttgaaaa atttatggaa atttctaact agcaataaac
     3601 gatgaaacaa tgaaatattt ttcatccaaa aagaactttg ctataatgat ggaagtttgt
     3661 gtataggaga tctggaaaat gagagagagt tttgaacaac aaaaaaaact gttgcatgat
     3721 cgctatggcg ccctttcgat ggatgaccgc cgtcaaatac tttgtaagtt gcgtaaaaga
     3781 aatatattga tgtatcgtca gttggaacgt ctgaaacatg atctgcttcg tttggagtca
     3841 aaacgtgtac agtgtgaatt agaggggaac caaacacagg ttgaagtagt cgaaaccaaa
     3901 attttaaaga aaaaagaaca atttttaaaa atgcttacac aaaataaaaa ataaagggga
     3961 tggacgatgg aatttgctga gttagttatt gtatttgcag taacgatcac cttatcgaac
     4021 atagctagcc gcattttgcc aatgattcca gctccactga tccaaatttt ccttggagtg
     4081 gtattaggtc tgacagagtg gggacaatca atcgattttg aacctgaatt gttcttagtt
     4141 atgattattg caccattgtt atttagagaa ggagaaaaag cagatatttc ttcgattctc
     4201 aaaaatttcg ggacaatttt gttcttggca tttggaggag tcattttgac ccttgtcggg
     4261 gtaggtgcga cgttatcatt cctgttgcca agtgtcccac ttgctgcctg ctttgctttt
     4321 ggagcagcgt taggtccgac agatgcggta gcagtcagtt ctctttctgg acgagtgaat
     4381 atccctaaaa aggcgatgca tattttggaa ggagaaggtc ttttgaatga tgcatctggt
     4441 gttactgcct tccagtttgc tcttggtgcg ctgatcaccg gatctttttc agcagtaaac
     4501 gcggggatga gtctagtagt ttctagtatt gggggagctt tgatcggctt tttgcttgtc
     4561 tggttcaaac aaaaaataat tcatttgatc gaaaaagcat cagcacaaga tgtcacaggg
     4621 tatctgctga tcgaactttt gcttcctttt ctagcctatg tattggcaga ggcatttgat
     4681 gtatctggaa tcattgctgc agtggcagca ggtattctcc aagcttctgg ttttaggaaa
     4741 atctctgtgt ttgatgcaga attgtcgagc ttgtcccaca gtacatggac aactattgct
     4801 tttacactga atgcattagt atttatattt ttaggaatcg aattgacgca agtgttctcg
     4861 ccagtatggg gagacggttt atatccaaac ggtcttttat tagcgattat cgtattaatc
     4921 tctgtcatgc tttttgtgat cagattcatt tctatcagtc ttttttatgt attcaaagat
     4981 ggcagtaaaa agttcaaaaa acagttgaac gagatcttga tcttaacatt tggcggtgta
     5041 aagggaacag tcagtttggc tacgattttt attttgccat tttcaatcaa taatatgatg
     5101 ttttaccagc ggtctttgct tttgtttctg acggcgggtg tcatcttagt gactttggtc
     5161 atagggatca ttgtcttgcc tatgctgacg gaaacagagg aagcgaaaag cacggatttg
     5221 aatgctttga tgattttaga agaggtcgtt gaagttttgc gaaaagaaat aaaggaaatt
     5281 gatcgtaata caaaagaatt tttagccact gaagcagtga tagaaaatta tcaagaacgg
     5341 atacgtgatc tgtacttgga agatttaacc gatgatgaaa agcaagaagt acaagaaata
     5401 caagcactga ttttgtcgat cgaacgggat ggattggatg aaagttatcg ttcgggcaag
     5461 ctttcttcta atggttatcg tttttactcc cgttttcttt ctcgattcga acattctatc
     5521 acaagccaga ttttgtcttt tatcggcttt tggttcattg ttgtccgtag gttaatgcga
     5581 atcgttctcc atccgaaaat gttttggcaa agaagatatg ctgatcgtca gacatttatt
     5641 agtgatgaag atatccaaga aatcagagag acatatcaaa aaaatactca gttgattatt
     5701 gaaagtttag ataacttgac tgatatttat gatgaaacga tggttcaatt ttttatccag
     5761 caacgcaaac ttgaaggaat aaaaatgaac tcggggaatt tgatttcttc gtggatgatc
     5821 cagcaagata gtctgtttac gaaaaaaatg ctaagaggtt attatcttga aagaaaaatc
     5881 attgatgaat acgaagttgc tgaaaaaatc acgacgtttt ctgcgaacag ctatcgcagg
     5941 aatatcaatt tgttagaatc ttatacgatg aacaaaccat ctgataactt ttctttccga
     6001 tttgcgtttc gagcaaagtc aaaaaaaacg agtccaataa aataaaaagg taaaaatttt
     6061 caagttttat aaaaaacaaa acatatcaga acaggatcga atcggtcctg ttcttttttt
     6121 gagaacacaa aaagaacaaa taccaaaaaa attttcctga agttcactat ttttatgata
     6181 caatatccaa gataaggagg gaacatgttg aaagaattaa aagtaactga cctcaaaaaa
     6241 acttatggtg aaaaagattt gtttgaccag atttcttttt tggtccacga aaaagaccgt
     6301 atcgggttga ttgggacgaa cgggacgggt aaaacaagtc tcttaaatat tattgccggt
     6361 atcgatagca gcgacggtga tcggcaaaca gtgttttatc caactgatta ccgtattggt
     6421 tatctttctc aagcagctga attttccgat gaattaactg ttctccaagc agtctttcaa
     6481 ggaaacagcc ccttgatcca aactgttcga gcatatgagg aagcattgat cgaactaggg
     6541 gaaaacggag aagaccctga tgtgcaaaaa cgttatgcta aagcagaaga acaaatgaat
     6601 aaagaagatg cttggactac agataccaac gcaaagatta ttttgcaaaa attaggaatc
     6661 agtgaattag ataaaaaaat cagtacttta tcaggtggtc agaaaaaacg agttagtctg
     6721 gcgcaagtgt tgattgatga acccgattta ctattactag acgaaccaac aaaccattta
     6781 gattatgaag cgatcgagtg gttggaaaac tatttgaaac aataccgtgg cgcactattg
     6841 atggttaccc acgatcgtta ttttctagat agagtagcaa accgaatctt cgaactttca
     6901 tttggaaaat tatacgagta taaaggaaat tatgaagctt acgtcttaga aaaagcagaa
     6961 cgtgatcgtg tagaagtaga acaagaagaa aagcgcaagc ggctttataa acaggaatta
     7021 gcttggatga gggctggcgt acaggcacgt ggcaccaagc agcaagcacg gatcaaccgt
     7081 ttcgaagatc taaaggagaa cttgtaccaa gtaaaccaag aagatgattt agagctgaac
     7141 ctagcgacac aacgtttagg gaaaaaagta ctggaaatca aagatggcag ttaccgtata
     7201 aatgaccaaa cactgctaga acatttagat ttattgattc aatctcggga aagactaggt
     7261 attactggta aaaatggtgc gggaaaatcg acattgctta atattctagc tggcagaatt
     7321 cccctggata gcggtacaat gtctatcggt gaaacggttc atcttgcgta ttatacacaa
     7381 gaaaatgaag aaatggcacc agataaacgg atgattgctt acttacaaga agctgctgaa
     7441 gaagcaaaaa cagcagatgg cagtcaaatc ggagtagcag aattacttga acgattttta
     7501 tttccaagat ttatgcatgg gacactgata ggcaaacttt caggcggaga aaaacgccgg
     7561 ttatttttgt tgaaactgct gattcagcaa cctaatgttt tattattgga tgaaccgacc
     7621 aatgatttgg acatagcaac attgacgatt ttggaagatt attttagaag ttttccaggt
     7681 gctgtgatca ctgtttccca tgaccgttat ttcttggaca aggtagcaga taagttatta
     7741 gtattccaag gaaacggaaa acaagaactt tattacggaa acatgtccag ttatttactg
     7801 aagcaaaaag agacccagca gcctgctgaa aaagcgaaac caaaaataca gagcaaggaa
     7861 cctgctgaaa agaagaaatt atcttacatg gaacaaaaag aatgggaaac gattgaagat
     7921 gagattgcag aacttgaaga aaaaatctca ttgctccaag aagagatgaa tcatcaagga
     7981 gataatttca ctcgattaca agaattgcaa aacgacgtat ctgaaacaga agcacaactt
     8041 gaagaaaaaa tggcacggtg ggaatacttg agtgaatggg tagaagatta ggaggaaaaa
     8101 ggatggaaca agcgtatctt gacttaggaa gaaaattgtt ggaagaaggg catcgtaaag
     8161 aagacagaac aggcacaggc acattaagct tattcggata ccaaatgcgg tttgatctgc
     8221 aaaaagggtt tcctttgtta acaacgaaac gagtaccttt tggattgatc aaaagcgaat
     8281 tgctttggtt tttaaaagga gatacgaata tccgctatct attacaaaat aaaaaccata
     8341 tttgggatga atgggcattt gaacgctaca tcaaaagtcc agactataat ggaccagata
     8401 tgactgattt tggccataga tgtttgacag atcctgaatt caatgaagaa tataaaaagc
     8461 agagcaagct tttttgcgag aagatcctaa ccgatgattc ctttgctgaa acatacggcg
     8521 atcttggaca catctacggc tatcaatggc gtcactggga aacaaaagac ggtggcttta
     8581 tcgatcaaat caaacaagtg atcgaagcaa tcaaaaagac tcctgattct agaagattga
     8641 tcgtttctgc atggaatccg gaagatgttc ctagcatggc tttgcctcct tgtcatacga
     8701 tgtttcaatt ttatgttcaa gagggacggc taagctgcca attgtatcaa cgcagtgggg
     8761 atgtgtttct aggcgttccg ttcaacattg caagttatgc gttgctgact cacctaattg
     8821 cacatgaaac aggtttagcg gttggcgaat ttgttcacac attaggagat gctcatcttt
     8881 atatcaatca tatcgaacaa atgaaagaac aattgagccg agaaatacgc gcatttccga
     8941 ctttagtttt gaatcaggaa aagcagtcag tatttgattt tgagatggaa gatatccaat
     9001 tagaaggata tgacccacat ccggcgatca aagctcctat cgctgtttag aatcagaaag
     9061 gatgagaaaa tgttagctgc aatttgggca caggatgaaa acggattgat tggaaaagaa
     9121 gaccgtcttc cttggcgttt gccaaatgat ctgaaattct tcaaacaaat gacagaagca
     9181 aatacactag tgatgggacg aaaaacattc gaagggatgg gtagccgtcc gttgccgaat
     9241 cgtcagacga ttgttttgac gagagattct tcctataaag cagaaggcgt gcatgtcatg
     9301 catagtgtgg aagacgtgct tgctctggaa aaagaaacag acggtatctt tttcatcgct
     9361 ggagggtcag ctgtttatca agaatttctg ccattttgta cgatattata ccgtacagtc
     9421 atccatcatg tattcgatgg agatgcttat tttccacctg ttgactggtc tgattggtca
     9481 ctgatcaata ctagtcaagg agaaatggat gaaaaaaatc gttatccgca tcaatttgaa
     9541 acgtatcagc gtaatgagaa tcctgtaaaa agcgggacag gcgaattgac gatataaaaa
     9601 agctatggat agactagctg ttatttagag ctgtcccatc catagcttta ttttttttat
     9661 taagtaaaga ataaaacaga gaagtacata aaacctgcac ctaacataac aaacaaatgc
     9721 caaacaacat gcatatagcg gatagaattc aagctataaa agaatgcgcc tatcgtgtaa
     9781 gaaagcccgc ctgctaccat caaaataaca ccagtcattc caagagagtg ataaagagga
     9841 acagcagcca cgacacagag ccaccccata aaaatataga tgatcgtaga tacttttgat
     9901 actctctccc gtttatgcaa cgtcaacgct ttatatataa tgccaagaat cgcaaacaac
     9961 cagattaata caaataaagt ccaacctagc catcctcgga tactcagcaa acaaaaagga
    10021 gtataacttc ctgcaatcaa aagaaaaatc gaactatgat cgaatacttg gaacaccttt
    10081 tttgcttttg taaaaatcaa tgaatgaaac aaagtagacg ttaaaaataa aagaatcatc
    10141 atcgatccat agatagcata agagacaata tggagggagg aatgcaagtg ggcacctttt
    10201 actaaaagaa ccactagtcc cgcgatactc aatccagtcc caattccatg ggtgactgca
    10261 ttaaacactt catttaatat ttcatacgtt cgattaaatt tcgttttttc catgaaaacg
    10321 gctcctttac taggtgtaat taatgaaaaa tcattatttg tctgttatac taaaaataga
    10381 aattgtctta catgtagttt aacatgaata aggcatcttg ttaaagaaag agagagagaa
    10441 aataatgaca aatgtaaaaa tcgtaacaga ttcttcatgt acgatggaaa aaaatgtacg
    10501 cgatgcttta ggcattcgtg tcatgccgct atccatcatg atcgacggaa cagtatatcc
    10561 cgatgatgac caactagacg gcgaaagatt tatggaaatg atggcgaaag caaaaaatct
    10621 gcccaaaaca agccaaccac caattggaga attcatctcg atgtatgatg agctaggaga
    10681 agacggcagt gaagtgattt cgatccatat gacaaaaggc ttgagtggaa cagtagaagc
    10741 agcaagacaa gccagtaatc taacaaaaac gaaagtaacg gttatcgaca gtgataccac
    10801 tgaccaagga ttatcttttc aggtaattcg agcagctgaa ttagcaaaag aaggtaaaac
    10861 agtagagaaa atccttgaag aagtcaaaaa agtacaagac aatacaaaat tatacatcgg
    10921 aatatccaca ctagataact tggtaaaagg tggaagaatc agccgaacaa ctggtttgct
    10981 gtctagtgtt ttgaacatac gcgtggtgat gaatttcgcc cattctgaat taatccctgt
    11041 aactaagggg cgaggaaaga aaacgttcga taaatggttt aataatttga aaaatgaact
    11101 gaaagaattg ccaaatgtgc gacaaatcgg tatttcacat gcggatgcaa aagaattggc
    11161 gcaagaattc aaagagggtt tgcaagaatt attcccggac atgcatatcc ctgtactgca
    11221 tacgaatccg gttatcgcta cgcatactgg taaagacgcg tttgcaatca tgtattatgt
    11281 agattagtcg aaaagaggat aagccctcag cctgaaaggc ttgcagctta ttctcttttt
    11341 ctttataaaa ttaggaaaat aattgttttc ttttttcata aagactacct ttttgataaa
    11401 atttttgata acattagaac caatcgaata caagaggtga aaaaatgaaa ttaacgaaac
    11461 gacatttgat cctcgttttg ttcccattat taattgcgat catcatctat gcaggtttag
    11521 ctgcttctat accgaaagct ggcccactaa tgaaaccagt aactactgtg agagaagatc
    11581 caaataaaaa agaaaaactt cactacatag ctatcggaga ttcgctgact gaaggagtag
    11641 gagatcaaac caagcaagga ggattcgttc cccttgtcgc aaatgatcta aaagaccgtt
    11701 ataatttgac cgcggttgaa acagaaaact atggtgtaaa tggtgaacga agtgaccaga
    11761 tcttaaagcg agtaaaaaca aaagaagaaa ttcgaaacaa tatcaaaaca gctgatttta
    11821 tcacactgac tgttggcggt aatgatttga tgaaagttat ccaaaataat ttattcgggt
    11881 taacggtcaa ttcctttaaa aagccactga aaaactatca ggaaaatgtc acagaactat
    11941 tggaagaatt tcgatccctc aataaaaccg cacctattta cattttaggc atctacaatc
    12001 cattttattt gaactttcct gagatcactg acatgcagac aattgttaac aattggaaca
    12061 aaggaacaga aacggtgaca aaaaaaatgc cgaactgcta ctttatccca atcaatgatt
    12121 tgctttatca aggattgaat caggaagtag gtgtcacaga agaaggaaca gatcaaacaa
    12181 ctagcacgac agaaaatcta aatggcatca aaaataatgt gctctatgaa gaagatcatt
    12241 tccatccaaa taatttaggt tatcaattga tggcaaatgc agtgagagat cagctgatcg
    12301 agacacaaaa ccaatggtta gagaaggagg atgatcaata aacatgaaaa caagatctga
    12361 cgtatcttca aacaaaacaa agaaaacaaa ttactggaaa ttcgccttcc ttatccttct
    12421 tggggtagta cttggttcga ccgtattttt aggcagccgt atttttgcta atcgggaacc
    12481 agaactccca gaaataccag ctcttacgga aagacaagga gatcctgtct taacgatcaa
    12541 ttcaaataaa gaaaaagtca atcaaatcat cagctttttc cttagtgagt atcaaaaaga
    12601 tagtgatatt gaatataaat tttatttgga aaatgaagca ctactcaatg gtactttcga
    12661 agtactaggt tttcctatcg atttctattt atattttgat ccgtatgtga tggaaaacgg
    12721 aaatgtccaa ctaaaagcta gaagtctttc tatcggaaca ttgagtttgc caatcaaaga
    12781 tgtgatgaat atgatcaaga gaaactataa attaccagat tggatcgaag tcaatacaga
    12841 tgatctgact atcatgctta ggttggatca attccgaatg caaaacggga tgtatattaa
    12901 agcagataaa atcgacttag taaatgatga cattcggttt agtctatatt tgccaaaaga
    12961 tacctctgat gcttcaaaca actcaaatac caacaaaact agcaccagca gtactgaaag
    13021 caagacaaaa gaaaataaaa aatcatcgga tgagtagtat tagaggggga atcataatgg
    13081 aacgagcaat atttgcagga ggctgcttct ggtgtatgat ccagcctttc gacacgcttc
    13141 ctggtatcca tacagtgatg tcaggatata ctggagggca tgtaccagat ccgacttatg
    13201 aacaagtaaa aagccaaacg actggacata cagaagcagt ggagattatc tatgatccaa
    13261 cattgatttc atatgaacaa ttagtagaac tttactggca gcaaactgat ccaactgacg
    13321 ctttcggaca attcgaggat cgcggtgaca attatcgccc ggtgatcttt tatttgacag
    13381 aagaacagcg gatcattgct gaaaaaagta agaaacagtt agctgaaagt ggacgtttcg
    13441 aacagccaat cgttacaaaa atcgaaccag cccaaccatt ttatctagca gaagaagacc
    13501 atcaagagta ttataaaaag catcctgaaa attttaaaag aaaccatgca cgccgggctg
    13561 cctttatcga agaaaattgg aggaacgaag ggtgaatcga agcttttttc attatttaat
    13621 gacactgcga ggcggtggca cacatgatgc tttatctgtt ttcgctacag aagccggtaa
    13681 agacatccaa tttcctaagc acagctctag ctacgaagaa atttctaatt atctggaact
    13741 gaatgtcgac tatttgccgt ccatggatat ctttgacgaa gcatgggaaa aatatttaga
    13801 aaataatcat gacatataag agatagtttt gtactttatg atcaaaaaag ttttttgtcc
    13861 aatagcctaa ttgaaagaat tatttttatt tcagctatct agtcgcattt ttttgatatt
    13921 tttcttataa taaagaaaga atgaaaaaaa gagggatgga ttgatagaga ttgacaaaaa
    13981 aacaacgcta tattaatcgc ttctggcttg tattcaaata cttacttgtt tctgtattcc
    14041 ttgcgttcat gttgcgggga tttttattca tcccggtacc agtggaaggc aattcaatgg
    14101 aaaacgtgtt gaagcaaggt gatatggttg tgatggaaaa attttcggag atcagacgat
    14161 ttgatattgt tgtttttcaa ttagcagatg gcacgattta tatcaaacga gtaatcggtc
    14221 ttccaggaga aaatgtcagc taccaaaatg atcaattgaa gatcaatggg aaagtagtta
    14281 aggaacctta tctaactaaa aacctgaaat cagatcatgc aaatgcatcc tatacgacgg
    14341 actttacact acaagagcta acgggacaat ccaagcttcc ggaagataat tattttgtac
    14401 ttggagataa tcgaagagtt tcaaaagata gtcgttcgtt tggcacgatc aataaaactg
    14461 atattctagg taaagcaaga tttgtctatt atccacttga tgaaataaaa tggatccagt
    14521 gagaaacaat aaagcgtgca gtctgttgag actgcacgct ttattgttta atccaaaatc
    14581 agtttactac cttagtacgt aaaatcaaac agctcgttta aacacttttc tagcctctaa
    14641 agttttgata aatgaataaa caaccattat ttgaataggg atttggatca tattcctgat
    14701 gaatctacct agaaaaatta ctttgaaatc tgcaccaaac aaaacagaca tcagccaaga
    14761 attgataaaa aggctgactg ggatcataat caataattgg gcagcgatga cggaaggcag
    14821 gtttatcttt ttatgatata aaaataagcc attaataaat ccaccaagga aagccgtgat
    14881 aagaaaagca gcttgaaacg ttcctgaacc aaatatcgtg aaatttaaag tgttcgacaa
    14941 catttcaagc aaaccagccc agatcggtcc atatagataa cccataagcg ccatacttaa
    15001 aaatccgaat gtgatttgaa aataagcagg accaatcgct atcttgtata agatgacatc
    15061 aagggctaat aaaagagcag aggtcgacaa caatcttgca ttcatttcgg gcaatctaaa
    15121 aacgtctttt gcaatcaaag tgttcaaaat attctctcct ttgtcagtta ataataaaag
    15181 gataccataa aatcaccaat gtgtcatgac acattggtga tttacataca ctggcatcta
    15241 acaattaaaa aaagggtgag aagactgctt ttataaactg taaaaaagag attgtacgaa
    15301 taaaaaaaat agaggcggag aatacttatc gtatcatccg cctttgtttt tttgttataa
    15361 aaaacgtcag attagttatc tgcttacatc ttcatccata cgggttctaa tgtatttccg
    15421 tctagatctt ggacttctaa tgaaaacatt tcttcttcag gcattcccat atctacttcg
    15481 tggaaagtac caccattttc ttttgcaatt tgagcaaatt tttttacttc atccgcattt
    15541 tcaacactaa acgaaatcaa agcaccactt gtttttttat tatcagctat ttctttatct
    15601 tttataaatt ttttataaaa atcatgagag agaagcatta tccaaaaagt gtcatcccat
    15661 accattgaac cagcttcttc agtagaaaat tcttcatttt ttttaaaacc cagcttttca
    15721 taaaaagcaa cggaacgatt gacatcagca acaggaaaat taacaaaaac catactattc
    15781 atttgtttcg tctcctttct gttttgttcg tctatcatct cttatttagg aaacgctgtc
    15841 aaaaatttag attcatatat agaaaccaaa ataaaaattt gcatcatcaa aaaagtgaag
    15901 atgtgataga atgaggactg gttcactttc acttaactaa tagatggaat ttcttta
//
LOCUS       DADQCX010000068        15812 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.068, whole genome shotgun sequence.
ACCESSION   DADQCX010000068 DADQCX010000000
VERSION     DADQCX010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.068"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            68..751
                     /locus_tag="J8R83_001962"
     CDS             68..751
                     /locus_tag="J8R83_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAZ9575091.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            753..1589
                     /locus_tag="J8R83_001963"
     CDS             753..1589
                     /locus_tag="J8R83_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9575092.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            1600..3354
                     /locus_tag="J8R83_001964"
     CDS             1600..3354
                     /locus_tag="J8R83_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575093.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(3630..3971)
                     /locus_tag="J8R83_001965"
     CDS             complement(3630..3971)
                     /locus_tag="J8R83_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAZ9575094.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(4039..6210)
                     /locus_tag="J8R83_001966"
     CDS             complement(4039..6210)
                     /locus_tag="J8R83_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAZ9575095.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            6421..7278
                     /locus_tag="J8R83_001967"
     CDS             6421..7278
                     /locus_tag="J8R83_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAZ9575096.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(7349..8206)
                     /locus_tag="J8R83_001968"
     CDS             complement(7349..8206)
                     /locus_tag="J8R83_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9575097.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(8191..10893)
                     /locus_tag="J8R83_001969"
     CDS             complement(8191..10893)
                     /locus_tag="J8R83_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAZ9575098.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(10906..12195)
                     /locus_tag="J8R83_001970"
     CDS             complement(10906..12195)
                     /locus_tag="J8R83_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAZ9575099.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            12345..13391
                     /locus_tag="J8R83_001971"
     CDS             12345..13391
                     /locus_tag="J8R83_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9575100.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            13393..15546
                     /locus_tag="J8R83_001972"
     CDS             13393..15546
                     /locus_tag="J8R83_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAZ9575101.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT         4491 a         3303 c         2919 g         5099 t
ORIGIN      
        1 ttgctccgtc ttcttctctt gctgttctgc ttcattgcct ataaaccttt atgaaagaag
       61 agataacatg cctactatcc atattgccgg tgattctact gcggcagaaa aagatgaaaa
      121 caagcgtccc gagacaggtt ggggagaaaa aatctctgct tatttttcac ccgagatcca
      181 gatcaataac caagcaaaga atggacgcag caccaaatca tttatccagg aaggaaggtt
      241 agcccgtcta gcttcacagt ttcagccgaa tgatttctta tttgtacaat ttggacataa
      301 cgaccagaaa atccaagaag aaagaggtac gcttcccttc ggtagctatt taaaaaatct
      361 gcagatattt tttgaatgcg caaaaaaagc gaacgtccaa atggtcttac tgacatctgt
      421 gacgcgacga gattacttag aaaacggaac attgaatcca gatatacttg gagactatcc
      481 aaaagcgatg cgtgcatttg ctgagaaaca ccatattcct cttttagatg tgttctcaag
      541 atcacaagaa ttgttccaga ccttctcaaa agaagagaca aaaaaattct acctgcatct
      601 tatgcctgat acttgtaaaa attacccaga aggactaaaa gacaataccc actttagtcc
      661 agaaggcgct gataaagttg cccgaataat tgttgaattg ataaaagaat cccgtctgcc
      721 tcttgctaat tatttacaaa aaggagtttg agatgtttcc attaaattta ggcatccgtg
      781 cccacgattt agatgttcga aatcgtgaag aaatcgttca aaaagtatca cagcttcact
      841 tgtcccatat ccaatttgca ccacaaaaag catttcctga acaacttaaa ttaactgaca
      901 tgacacttgg gagtgctgcc tattttggtg aatacttcca aaaaaacaat atcgaacttt
      961 ccattttagg atgctatatc aacctatcca gcaaaaatca agaagttcgt gcacaagcat
     1021 tggcaacttt caaacagcaa attgctctgt gctctgccta tcaagccaag atgattgcta
     1081 cggaaaccgg tagtgtctct gtcggttaca caaaagaaaa ttttactgaa gaagcttatc
     1141 agatcgccag aaattctatc attgaattag tcgctcatgc agaaaatttt ggcgtaactg
     1201 ttgctgttga agcagggatc aatcatccaa tctataacta tcagttagct aaacgtttaa
     1261 tcgatgaagt agcttcacca aatttaaaaa tcattttaga ttgtgcgaat ttgatgcata
     1321 aagaaaatca tgctgatcag gaaaaagtga tccgaggtgc cttggacaat ttacatggtt
     1381 atattacagc gcttcatctc aaagactata tcatggaaaa tggaaagatc cgcatggtac
     1441 ctgttggcaa gggctgttta gatttccgcc cggtactgca ttatatcaaa tatgagcgtc
     1501 ctctaatgta cgccactctt gaagctactc ctgagattta tgttcctgaa gcaatagaac
     1561 acttgcagtt tatttaccaa gattgttaag gagaagatta tggaggaacg aatacagaaa
     1621 agttatcaaa aatatcatgc aaatgctttt cagacattgc tgcatcttta tcagggaaat
     1681 tattggcgtt ttgccatgtc aggactcttt tttattatca aacatcttcc atcttggtta
     1741 atgccgatcg ctattgccaa tgtaatcaat gcagcttcat cgaaagattc ttctcagttg
     1801 caggccattt atttcaacgc ttttttgatg gcttgtctga ttggtcaaaa tatattgacg
     1861 aattattttc atgtaaaata ccatagcact tcgatccgtc aagtagaagc tggactaaga
     1921 gcgaccctta tcaagaaaat ccaagaacta tctattcctt atcaaaaaga attgcaatct
     1981 ggacgaatcc agtcaaagat catccgtgat gtagaagcta tccaaacgtt gtcctctcaa
     2041 gtatttgtca gcggattaaa tatcgctgtc aatttattcg tagctttagg tatcacgctt
     2101 tataaaagtc ctgttgtttt catgtttttc ttattgactg ttcctctcgc cgcattcgtt
     2161 actctctttt tccgtaaaag gatcagacag tccaactcag acttcaggca agaaatggaa
     2221 gagacttctg caaaagtgat cgaagtgatc gaattagcac cgattgctcg agctcatggg
     2281 ttagaaaaac acgaaacaac tcgcttaaat aagcatttta ctcaaatcta tgaaaaagga
     2341 ttccacttag atatcctgca atctgttttc ggatcagtca gctgggctag ttttcagata
     2401 tttcagctga tttgtttgag tttcactggg atattagctt tacaagggcg catccaaccc
     2461 ggcgatgtcg tgatgtatca gacgtatttc acgacgatcg tcaattccgt ttctggaatg
     2521 atcacgctga ttcctacgat ttcaaaaggc atggaatcta tcacttctat tggcgaactg
     2581 ttgattgctg gcgatgtaga aacttatcac ggtaagaaaa aaatccaaca tttggatgga
     2641 aattttcgtt ttgaggatgt ttcttttctt tatccggact cactcaaacc gattatcgat
     2701 catttttctc tagaggtgaa agctggagaa acaattgctt ttgttgggcc atctggctct
     2761 ggaaaatcta cactccttaa cttattgatt ggatttatcc agccgacttc aggaaaaatt
     2821 tttctagatg atcagccttt ggatgaactg gatatgcgaa gtgtgcgaaa ttatttagcc
     2881 gttgttcctc aaaccacttt gttgttctcc gcttcgatca aagagaacat cacttatggc
     2941 ttgaaaaacg tatcaaaaga acgtttagat gaagtcatcg aagctgcgca actttcttca
     3001 ctgattgacc agcttcctga tggtctggat accttagtag gcgaacatgg caacaagctg
     3061 tctggtggcc aaaagcaatg tatctccatt gcacgagcgt tgatacgtca gccaaaaatc
     3121 attttgctag atgaagcaac ctcagcttta gataaccagt cagagaaaaa aatccagcaa
     3181 gccctgaatt acctgacaga aacacccact acttttattg tggctcatcg gctttcaacg
     3241 atcaaagagg cagataaaat cgttgtgatc gatgaaggaa aaatcgttga aataggtact
     3301 tacgaaaaac tgttagctca aaaaggctat ttctaccgct tgaaaaatga atgacaaaaa
     3361 ataggagcta tgacaagact tttgtcgtag ctcctatttc tgaataaacg gtgttctcct
     3421 gccaactcct cggtcacaag tcacaatagt catcaaacat gagaagctgt tttttgaaat
     3481 tgttccttgt aactcagagt taaacggtag gctcacgacc tcttggtaaa tggtgttcaa
     3541 gagacagcct atcggcaata agaagcaatt ttgtcatcgc tcaaggccga acgtctcttt
     3601 cacaccctct gttgtttcat aaaatagttt tattcgctgt aaaggtcgcg aactggtgtc
     3661 atgatgatac ggttcaagtc attgatgatt gtactgaagc cttgctcttt ttgcatcaag
     3721 tcattgatta cttcttctga ttggattttc acagccattt cttgtgcttt cattgcatct
     3781 tcgtcgctga actcttgtcc actcatttgt ttttcttgta attcgatttg catcgcttgg
     3841 aagtctttga acagtttgtg tgcttcttcg tttgcttgta ctttctcgta cgcttctttc
     3901 aacgctttga attctggtaa ttcacggatc tcacgttcga tttgattcgc gctatcgtag
     3961 atgtttgaca tgttatgccc tcttttcttt tagtagttac tctctattgt aacatggggt
     4021 tattcgtttt caaaggggct actctccttg atatttccgc cagaggtctt tagccgcttc
     4081 accaattccc tgaacgcctt ctttcaccat atcgccgaag tttttcagcc cttcttttgc
     4141 ttgttcacca tattgattca agttatcttg ccaatttcca gactctccat tagaatttcc
     4201 tgtgtttcca acttgatctg cagctaccac ttgtcctcct gtggcatagg catctgctac
     4261 actaaatcct gtttttgaag tatacggaag gatgccttct gccgctgatt tgaagacttt
     4321 cccgacaaca tttccacttg tcccttccaa atagtgcagc ttgctggatt cttcgtaacc
     4381 catccatgtc gaaatcacta cgtctggcgt gtaaccgatc atccattggt catttgcttt
     4441 tgtggcatcg aaattagttt ctgtggttcc tgttttccct gctatcgtat aacctgcagg
     4501 attcgcagca gccgctgttc catttgaaaa tgtaccaaga agcatgctgg tcatttcatc
     4561 ggctgtttcc tttgatatga cctgttttgg ttttttgttt gtgttatcga cgatcaccgc
     4621 tccagtcgaa tcaacgattt tcgtgataag atgcggcgta tacatctgac catcattggc
     4681 aaatgcactg taagcacccg ccatgatcaa tggagatact cctttttcca gtccaccaag
     4741 ggctaagcca taatacttat cagattttgc taaaggcagg ccgaattctt ctgctttatc
     4801 atatcctttt tgtaaaccga tctcatgcaa aagccataca gcaggcaaat tcaaactttg
     4861 tgcaacagct tgatacatcg gtacttctcc ttggtatgtc ccgtcaaaat tatgcgcatc
     4921 gtaataactt tgcggttcgt ctttcaagat actggaaggc ttgtatccag cttccagtgc
     4981 tggtgtatat acgcttaatg gtttgatcgt tgatcctggt gaacgacgca tctgtgtagc
     5041 aaagctgaat cctctaaaga catgatctcc tcttcgtcct actagtgctt gtacaccacc
     5101 tgtattcgga tctaaagcta ctgaagcaga ttggaccatg gcaccatctg aagcatttgc
     5161 tgggaataat gcactgtttt gataagtagc ttctaattgc ttttgataat cctgatctaa
     5221 agctgtatag attttatagc ctttattcat gacatcttct tcatcaagac catactcgtt
     5281 aactgcttca tcgatcactg catcaaaata ataaggataa cgataaccag aatctgaatt
     5341 atcgtatgtg tcattaagat acgcgctgat atctgtctgg ctttctgctt gttcttgttc
     5401 ttttgtgatt tttccgtttt cttccattac acttagtact gtgtttttcc gatcattcgc
     5461 attttttggg tgatcgatcg gattataaat accaggacct ttcagcattc ctgccaaagt
     5521 agcagcctca gacagcgtaa cattcgttgc atctactcca aaatactttc tggaagcgtc
     5581 ttggacaccc cataccccgt tgccaaaata ggcattgtta agatacatgg tcaagatttc
     5641 ttctttgctg tacttctttt cgatctcgat tgccaaaaat aattccttcg cttttcgatc
     5701 aaacgtttgg tctaatgtca gatacgcatt tttggcaagc tgctgagtga tcgtacttcc
     5761 tccgccccct gatgttccgc cagacaagac cattcggact gctgcacggg caatcccttt
     5821 gatatcaaac ccgtgatgct cgtaaaaatt cctatcttct gtcgagatta ctgcatcttg
     5881 gatataggga gaaatcgcgt ttaattctac atatgttcct ttttgggcgt acagtgtgcc
     5941 agcttcttcg tttttcttat cataaatgac tgtcgattgg cttaatcctg attttaacgt
     6001 ttcgacattt gcttgttttg ctaaaataaa gaggtagata cttgtcacta agacacagat
     6061 caaaccaatc agcaaaatca atttgttcac atgatatttt ttccagatgc gctttcgcca
     6121 tcgatggaat tgtccgagat atggtctgat ccaacgccaa aaactgatca aagcagcttt
     6181 tatcttttct aaaatgcttt gaaaatccat ttgcttcttc tcctgtctat ttgattcaat
     6241 cgtcttattt taccatagtg aaagagtgtt ttcttcctgc ttaagttgta gttcaatatg
     6301 tttttttacg ttagtgcaag tagagtaaca taagaatgaa cagaaaaatg taagtttttt
     6361 cttaaatatg ttttaaaaat ggtacaatta gtctgcaatt gcactgaaag gagtacactt
     6421 gtgaaaatca cgatcacttt acctatgaac catcctgaaa caacaattcg cgacttgctt
     6481 gaaaaggaat ggttagttcc tagaaaggtt cgacactttt tgcgtatacg taaaaacgtt
     6541 tggatcaatc aacaacctgc tttgttccat catgaagtaa agggcaatga ccagatcaca
     6601 ttgttattcg aagaaacaga ttataattat caagaagttc aattaggaga tgcgaagcac
     6661 atccgtgttt tatatgaaga tgagcatttg attatagtgg ataagcctgc aggaatgaag
     6721 actcatccaa atgaaccgac agaaaacagt accttactca atcatttagc tgcttatctc
     6781 gacactaaac agcaacgacc ttacgttgtc caccgcttgg acaaagaaac aagcggtgcc
     6841 gttttatttg caaaaaatcc atttgtcttg ccgatacttg gaagaatgtt ggaacaaaaa
     6901 atgatctatc ggagatatca agccatcgta tggggagaaa ttgccaaaga tatgaccatc
     6961 accaataaaa ttggacgaga tcgccatgat cggagaaaaa gggtcgtaga tgataaaaat
     7021 ggtcagagcg ccttgacaca tgtcactgtc aacaaagtac tttctgaaca aacacaagtc
     7081 tattgtgttt tggaaaccgg acgtacacac cagatcagag ttcatttagc tcataaggga
     7141 catccgatcg ttggagaccc tctctaccaa aatagaacag ctgaacgact gatgctccat
     7201 gcattagaac tgcacatgat ccatccattt actcaagaaa aaatagtcgg taaagcttta
     7261 cctggattat gggaatagaa ataaaaaaga acagagtctt atcagcagat aatgataaga
     7321 ctctgttctt tttgtgtaat ttgtctgctt acttttgatg ttcgtgttct gctaacagca
     7381 aactaccgat aatcccactt tcattcggca gtccccaacg aacgatatat tcacttactt
     7441 gaggtgtttc catataacca cccatcaatt caacaaattg ctgacggatt ttttgaagga
     7501 gatgatcctg attcattacc ccaccgccta aaataatctt ttcaggtgct aacgtcaacg
     7561 tatagttgat cagtgcttga gcaatataat aagcctgaat agcccaaaca ggatgatctt
     7621 gcggcagatc ttgccctttg atccctgtgc gtgcctcaat agacggtcct gctgctaatc
     7681 cttctaaaca atctttatga taaggacaag taccttcata atggtcatct ggatggcgtt
     7741 tcacccaaat atgtcccatt tcaggatgtg cgatccctga aaaaatttct tcattgatca
     7801 cgacacctgc accgattcct gttcccacgg taaggtaaat acaactattt tttccttgtg
     7861 ctgctccttg cttcaattcc ccatatgcag cagcattgac atccgttgtc caagcagcag
     7921 gaatattgta gcgttccttg attgtgccaa gaaaatcgaa ttgtgcccac ccttttttgg
     7981 gagttgccaa aacgtatccg taattatctt ttgttttgtc gataccaatc gggccgaatg
     8041 agccaatccc gattcccttc aattcataac gatcaaaaaa ttcaaatacc tgatccaatg
     8101 tttcttctgg tgttgtggta gggatactta atttttctaa aatttctcca ccatctgaaa
     8161 ccgcacacac aaattttgtt ccgcctgctt ctattccgcc atacattcgt tttcctcctc
     8221 gaatccgatt gtccgaatct cataaggttg gattattggg acaaccgctt gcttcgttgg
     8281 ttcttcaagc agattcaata tgacagtttt tccattgtct ttagttattt ccaatttttc
     8341 taaatgacta gacatattga aacctcttac tactacttta tcactaaact tgctgcgttt
     8401 caaagctgta attgcaaacg tttcactttt tatcgttaaa tattgttgtt ttgaaatcaa
     8461 tgttccttca tgatgtttga tttgttgagt ggaaaaagga atctgtgctg cgtatgcatg
     8521 caaataagta gagaattttt cttctggtcc atgtagttca atgctgtaat tgaaccgatg
     8581 ctcacctaga cactgtgctt ctggtgttgg aaaatatccc caatcgccta gttctcccac
     8641 actgcgaagt agcgtcactg cgatttgtcc gtcttctgtt acttcatatt cattcaaacc
     8701 aaagtttccg actgttacac cgtactcttc atcatgaata ttgacaaatg cttgctgatg
     8761 ttgcggattc gtggggtttt cccaactttt agacacatgg tttgggcgct tcaccacttc
     8821 aaaaatacta tctgcttcgt gatgttccac atgtaacttt gtaggaaaca agacacgtaa
     8881 gcgatgatct ttcatctgat tgtcgagagt cgtttcaaag tcgatttttt tactatcttt
     8941 tctgattgtc atgattgttt ttatttgaag gattcgtttt tctttggatc gttctgcttt
     9001 tcgataacga aattccacaa ccatctgctg ttctttttct aaacgctcgt ctgcagaaac
     9061 agggatttcc atttcctgta gaatacttat ttttgctatt tccggtgtat ctactaatac
     9121 ttttacttca gagttttctt tgttactgga taggattggc tgatcacaga aaggttgttt
     9181 aaagatatac tcatttccta tatcgccgat atcttcaaaa atatgcagat tattcaactt
     9241 tcgtttgttt ttgcgatctt ccattgtaat ggtaccattt ttttcaatcg tcaaatgtag
     9301 agggccgttt tcgatgattc gtccactctg atgaatcatt gtttcctttt cttctgcttt
     9361 cgcttcccct tctacaagcg cgaatgtttc ccaagaaaat gctggcatgt tttctaatgg
     9421 taaagtcact ttgatcattc ttgccatata tggcacacgg aaacggtctt tcggcaaatc
     9481 ataaccaaat tggacagttt cttcagataa aatagctggt atagtggccc cactttttgt
     9541 ttctacatga tacttacgtt taggcaaatt ttctaactct tgatatagtt gttcaggtat
     9601 tccttcagcg aatctttttc tttctaattc gatggttatt tctgcttcac cagttttatc
     9661 cattcctgca gtatttacaa tgacaaatgg aaagctgtct tttgggaatc cggtcgtatc
     9721 gattgctgcg gtcagctgtt ctaaggaatc ttgtgcaaga tactttccaa cttcatctgc
     9781 tttttcaaaa cgaggtatca tttcccgatg gacagaatcg actgaacaac cgcaaatact
     9841 gtcgtgagga tgattttgca ttaatgtctt ccaagcataa tctaattgat catggggata
     9901 gtttccacta acttcataag ccatcgtcgc aagtggttct gtaatatttt ctagctgtcg
     9961 ctggaccttg gtattccatt gttttaagta aacccgagca gatgctgtat tggctaaagt
    10021 ataccagcca tccgtttctt gacttgtcaa ttctccttct actgagccta agtcttctgg
    10081 cacatctttt tgaactgctt ccagatagtc agtaaaatta gaatgaataa actcgtaatc
    10141 tggaaacagt tcatttgcga gatggattgc ttttgatata tctttttgta ccggttgatg
    10201 atcaacacca ttcatcatca ataagtggtt cgtagaggca tattgttctg catccgctaa
    10261 tttttgcttc caaaaggcaa gagctgcttc tttttctact ggaatctcat tcccgttgct
    10321 ataccaattg gcaaatagca gaccaaagat tgctgtttga tcagggcctt tccaccacat
    10381 ctctgagtat tgggaagaat agttttctgc ttccaaaact tgattatcaa agccaattgg
    10441 ttttacacca cggccaaacg ctgctgctga aataccagct tgtttcatta attgaggcgt
    10501 ctgtcccata tttccaaatg tatcgggaaa atagcctaac atgacagggg ttccccattt
    10561 acggctttct tccatgccaa tcagcatatt tctcacgttc gattccgagc tgataagaaa
    10621 atcatcttgc aagatataaa atggtccaat tctcaatttt ccttcattga ttgcttgttg
    10681 gattgcctgt cttttttctg gccttacttg aagatagtca tctaaaataa tcgtttgccc
    10741 atccaaatga aaactgttga aggacggatc aacttcaaat agctctagta gatcgtctat
    10801 caattcaatc agtcgcatgt gatgctgttc gtaagccatg taccattcac gatcccagtg
    10861 gctatgagaa atgatatata ctttcttttt catttacgat acctcctact tttctactct
    10921 aatatcaaag taatccatga ctaattcgca aaacatcata tttgcccaag aaaaccattc
    10981 tctcgtataa ttttcaggat tgttcacatc gaatccttcg tgcataaggt gtgttcctgc
    11041 gtcagttgct acaagtaaat tcaatatccg ctctttttca gatttgtctg acgttgtcat
    11101 tccttccata gctaatgcaa tcggccaaac gtatttttct ggcgtatggg aggatccaat
    11161 tccttttgcg tactttcctt catagaaata tggattttct ttactcaaca atgttcttct
    11221 tgtttgcaga taatcttcct cttgttcaga acaatatccc aagtaaggtg cggcgatcag
    11281 attgggcaca ttactgtcat ccatgactgt ggcgtttccc attccatcta cttcatatgc
    11341 ataaatcgtt tgcccttttt gattaaccgt tcgtccgtga ttctgaatcc cctcttggat
    11401 ctctttcttc aatttctgtg tttgctgtac aatttcttta tcatcgagta tcgtttgaaa
    11461 aatttcttcc acataaccta acacgaccac cgcaaacata ttggatggta ccagatatcc
    11521 ataacggcaa gcatcatcgc taggacggaa accagaccat gtcattcctg taaaagctgt
    11581 ttttgcacct cgcccgtcat tgatcagcgt atcttctttt cttgtcgtgt ctcgtacaaa
    11641 tgtataagga gagtgttcat gatcttgctc tgttttgaac acgtccaaga tttttttgat
    11701 accttcaata aaagattgat tgaattgatc agtttttcct gtatttttgt aaagaagata
    11761 ggccaactgt attgggtagc ataaagaatc aatttcatat tttctttccc agatccaatc
    11821 gttcattttt gtatgatctg tttggtggcc agcaccgtta gcttcttcgt tgaaggcatt
    11881 cgcatatgga tcgatattga tataaaaaaa ttgctttttg actaacccgc tgatcatgtc
    11941 agctaattcc tcatcttctt ttgcaatcac taaataagga cgaacttgtg cagtagagtc
    12001 tcttaaccac atcgctggaa tgtctcccgt caataaaaag gtggttccgt cattttgctt
    12061 tttgactgtt gtcaacagag tattggcaaa tgctgctgta aaattctttg cccagtccgc
    12121 atggatatcc ccacattttt gtgtgatatc ttccataaat ttctgcaccg attttggtat
    12181 atctttataa accactaata aaaccttctt tctatttgat atatctttaa agattatact
    12241 tcatacagcc aattatgtct acgctttcaa aaaatatctt tttatttact ttttcatcca
    12301 ttatggtatt atttgaatat gatatatcat taagaggtgt ttatatgact caaccattgt
    12361 accagacaat atttaatgat ttgcaaacgg ctattttaac tggtgaatta cctgtagaca
    12421 gccaactacc aactgaaaaa gaactttcac gtacctataa agtaagcaga atcacttcca
    12481 aacgtgcatt gactgaatta gagcaattag gacttattta tcgcgttcgc gggaaaggca
    12541 gtttcgttaa atccgcttct ccggaacaga ttcttgcttc tcctacaaaa acacgacgga
    12601 ttctgtttct tcttccatat gtcgctgatt tgtctgttgg tgattttagc aagggattga
    12661 accctgtgat gcaagataaa cagattgatg tcatgatgac gacgcttgac tttctacaaa
    12721 ataaaacagc aaaagagcta atcaatgaat ttgacggatt gatttattat gctcttgata
    12781 cagaacaaca tcttgactta ctttttgagc tttcattgaa agaattccct gtcgtcatat
    12841 tagataaaaa aatctatgag ttaccttttc ctaccgttct ttccgataat ttccaaggcg
    12901 gtgcgcttgc tgcctcttat ttgatcgaac agggacattc aaaaatcgct tatttgtttg
    12961 gtacgcagac tcatccacaa tccgttcgac agcgttacct tggttacctt gaagcattgg
    13021 acaaagctgg tttgactttc cacacttcac tggatgacaa aagcgcgaca ttagatgaat
    13081 tgctttctta tatcactaag tatgaagtaa ctgcttttgt ttgtgaaaac gatgttgtcg
    13141 ctatccagac catgaatctc ttgagacagc atggttatca tatccctgaa gatttttcaa
    13201 ttatcggatt tgatgatatc caagcagcag ctcttgttga cccgccactg acaaccatcg
    13261 cacaagattt tgaacagtta ggtaagcttg cgggagatgc tttggtcact tggttagaga
    13321 caaaagatcg accatccgat agtaaatttc cagtttcatt catcaaaaga caatcaacaa
    13381 aggagaaata aaatgaatat cggtcaaata gatactagac atgcaacagc gaatcagcca
    13441 aatttctcta atgggaactg ccagccttat actggcgttc cttttgggat gaattatttt
    13501 gcaccgcaaa ctacggatca aaacggcagc tggtggtttc atcctgatga ccgcgttttt
    13561 caaggctacc gtcttaccca tcaaccaagt ccttggatgg gtgatttcag tcatatgctg
    13621 tttacgccga tcaatggaaa actacaggag aacacccttt tccatgctca aagttcttac
    13681 cgcccagaag aaagtatatt ttgcccgact catctgtcga tctgtcaatt acgttatggc
    13741 atctgttcta cattgatacc tagcatgtat ggcggaatct tatctattga ttacagcaaa
    13801 aatgacagcg gtttactttt atcctttccg ggacgccatc agctctttgt tatagatcct
    13861 tacacagtgg aaggaaaaat cacacatttt gctggttcag aagatcctga tttttctttt
    13921 tattttatat tgagatttga atatccttta acaattgatg agttagctgt ttccaacaaa
    13981 aatagcgact cgatcccgtt gtattttgaa cagacaaaaa aacaaactat ccgatttggg
    14041 acatctttta tcagctcgga acaagcagct tataacctgg aactagaaca aaaccaaagc
    14101 aaagagactt accttgctca cagtcaagaa caatggcagt cctattttga tcgtatacag
    14161 ctcacacacc atgatcaaca acaattgcgg acgttttatc ataatttata tcgggtgttt
    14221 ttatttccac aaacatttta tgaaattgat cctagtgggc aaaaaatcca ctatgatacg
    14281 actagtcgat ctataaaacc tggtgttctc tatacaaata atgggttttg ggatacgtat
    14341 aaaacggttt atcctcttta ttctttgatt gctgtagaaa aatacgaaga aatgctggaa
    14401 ggttttttga acagctatag agaaagtggc tatttgccaa aatggctgtc tcctgatgaa
    14461 cgtggactta tgcctgggac attgatcgat gcggtcattg cagatgctgc tgtaaaagat
    14521 atccgacgag acttgatgcc tgaatttcta acggcaatgg aaaaaggtgc tacggttcaa
    14581 agcaaacatc caaattatgg acgccaagga acagaagatt acttgacata tggctatgtt
    14641 cctaatcact accacgaatc agtcaatcac acattagact atgcttatag cgatttttgt
    14701 attagccaag ttgccaaggt actagaagaa gaggaaatga cgaagaaata tcagcagcaa
    14761 tcattgaact atcaaaatat ctttgactat gagtcaggat ttatgcgttc aaaagataaa
    14821 gatggcaagt tcagagaacc attttcagct aatcgttggg gacaagatta tgcagaagga
    14881 agtgcttggc aaagcagctt tgctgtttat cacgattttt caggactgat cggaaaatat
    14941 ggtggcagtg agagatataa agaaaaactc attgagctgt gcaatcagcc cccaacgttt
    15001 gacccaggag gatatggttt tgagatccac gaaatgagtg agatggccgc gatagaattt
    15061 ggacaattag ctatttcaaa ccagccaagt tttcactatc cttacttgtt cagttatata
    15121 ggacaacctg aaatggcaca gccactgctt aaacagttga tgactcagac cttcgacgat
    15181 tctccaatgg gttaccctgg agatgaggac aatggaagta tggccgcttg gtatatcttc
    15241 aatagtctgg gattttatcc tgtcacgcct ggaaccggtg aatatgttat cggtatgcca
    15301 ttaattgaca aggctgtttt gcttttgtca aatggaaagg aattgacgat tgaagcaacg
    15361 cctaatcggc cgcagcaaca atttatccat aaaatcaaac ggatggacag agaatatacg
    15421 aaattatatt ttacccatca agatttgctg aaaggcggca cgatctctta ccaattaggg
    15481 atcatccctc accctaagaa atatcaagca aaagatttgc ctttttcctt atcaaactat
    15541 aattaacaag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaagcaaa
    15601 aatagatcct catatttttc gtttggttgg tcttattacc gcagatgcaa gcttttgaac
    15661 accgtttatt gagaggttgt gaaatcagcg ttctgacctg agtattagag agacaaatgg
    15721 caaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca gctgattgaa
    15781 caccatttag tggagaggtc gtgaaaaagc tg
//
LOCUS       DADQCX010000069        15243 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.069, whole genome shotgun sequence.
ACCESSION   DADQCX010000069 DADQCX010000000
VERSION     DADQCX010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.069"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            167..361
                     /locus_tag="J8R83_001973"
     CDS             167..361
                     /locus_tag="J8R83_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575102.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            630..929
                     /locus_tag="J8R83_001974"
     CDS             630..929
                     /locus_tag="J8R83_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575103.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1026..1460)
                     /locus_tag="J8R83_001975"
     CDS             complement(1026..1460)
                     /locus_tag="J8R83_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575104.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1692..2402)
                     /locus_tag="J8R83_001976"
     CDS             complement(1692..2402)
                     /locus_tag="J8R83_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAZ9575105.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2392..3252)
                     /locus_tag="J8R83_001977"
     CDS             complement(2392..3252)
                     /locus_tag="J8R83_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAZ9575106.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3257..3895)
                     /locus_tag="J8R83_001978"
     CDS             complement(3257..3895)
                     /locus_tag="J8R83_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAZ9575107.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3910..4209)
                     /locus_tag="J8R83_001979"
     CDS             complement(3910..4209)
                     /locus_tag="J8R83_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9575108.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4252..5736)
                     /locus_tag="J8R83_001980"
     CDS             complement(4252..5736)
                     /locus_tag="J8R83_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAZ9575109.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5756..6217)
                     /locus_tag="J8R83_001981"
     CDS             complement(5756..6217)
                     /locus_tag="J8R83_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9575110.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="J8R83_001982"
     CDS             complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="J8R83_001982"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAZ9575111.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7520..8290
                     /locus_tag="J8R83_001983"
     CDS             7520..8290
                     /locus_tag="J8R83_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9575112.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8563..9390)
                     /locus_tag="J8R83_001984"
     CDS             complement(8563..9390)
                     /locus_tag="J8R83_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575113.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9958..11193
                     /locus_tag="J8R83_001985"
     CDS             9958..11193
                     /locus_tag="J8R83_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAZ9575114.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12192..12452)
                     /locus_tag="J8R83_001986"
     CDS             complement(12192..12452)
                     /locus_tag="J8R83_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAZ9575115.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVTHLNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12479..13780)
                     /locus_tag="J8R83_001987"
     CDS             complement(12479..13780)
                     /locus_tag="J8R83_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9575116.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14072..14530)
                     /locus_tag="J8R83_001988"
     CDS             complement(14072..14530)
                     /locus_tag="J8R83_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAZ9575117.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14543..>15243)
                     /locus_tag="J8R83_001989"
     CDS             complement(14543..>15243)
                     /locus_tag="J8R83_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAZ9575118.1"
                     /translation="KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITK
                     NFPSNIPNNYLEYYLYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVL
                     NFNFGEHGQYIVDIAISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEP
                     ITLRKPISDFHKGLMEAQVAVEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILD
                     EMIKVNKKYWPALK"
BASE COUNT         4876 a         3105 c         2365 g         4897 t
ORIGIN      
        1 aagaacaata gccttttatt atatatatta ttcaaattag ttatatcgag tgaaaaaaac
       61 tttcaaattg attcttttta tttatcataa agatatagat acataatcat tttcacttac
      121 atatatttga atattaacta aaaacagcaa gaaagaagag gatcaaatgt attatgtaga
      181 agtaaaaaca aaaggcgtca aaaacaaaca atatgtgaaa ggtatcagta acgaatatcc
      241 tttacttggt tcatggaaag aagctgctcc tttttccaaa ccatgtgcca taaaaataaa
      301 gaacgagcta gaaaaagaac tgacttgtgg taaagctgtt gtagatatca tcgaaaagta
      361 aatccaatgt atagaaagga agatcacaca tgaaaagcga cgtacaaatt gctaagatta
      421 tagaattaga agaagaagac gcagtgttga caattgaaaa aaaataaatg tttgtatacc
      481 atatgattat ttcaatatgt atcctggaat tggagatctc gtagagctat atcaagatga
      541 atcaaatata cttgtcattc atcatgaaat atagagactt ataaaattgt ttatttttat
      601 aatgtatcag tatagaaagg aaataaaaca tggattatac tgttgaattt gacagtgaac
      661 tacttaagca atttccacaa gaagaacatt tcatgtataa agaagcaatt tcccacaaag
      721 tgacagagta tttggagcat aatttttttc gtataaagcc agtgcgtact cgttcggcaa
      781 aaggaatata cgagatgaaa gtcaaaatta ataaaaaaaa ttatcgcata gcatttgctt
      841 taaaaaaaaa tcatgtgttc attttttata ttagttcgaa tttgcaaaaa attgtatttg
      901 ataaagaggt gagtaaaaaa ataaaatagc tgagcattgg aggatagatt gagtgatact
      961 aagtctatcc tcttgttttt ctaaagaact aagctagaat tttttctttt gtacgttatt
     1021 atatgttatt tgtcattacc aaaaagcacc ttttttcttc tagtatctat gacataagaa
     1081 ataccaccca tttcctttac ttgaacaaat cctactgatt cataaaattt ttttgttttc
     1141 tcagtatcat ctgtcaataa ttcgatttgg actggtccat aactagtgat cttctccaaa
     1201 gcttcattca aaagcacttt gcctattcct tggcgctgat acctcggatg aatgaggata
     1261 tcttgaataa atgcgatcgt cgcaaaatca gtgatccaac gaacgattcc gataatcttc
     1321 ccttccccat tacgctttat cagagattca gattgttcaa atgctctagc taaccttgca
     1381 gtgtcttttg tgtaattcgt ccaaccaacg ctcttatata attcagaaat ctcatcgatc
     1441 ataagggaat caatattcat ttttttcttc ctttcttata caattctccc tctaataata
     1501 cagttctttg actatttaat ctatcacata taactctcct gtaaagattc tctcgattcc
     1561 ttaaaattcc tctttccttt tagaatgcat actttttgat aaataaaaag gttgtgataa
     1621 attttcttca caacctctgt ttctctctat caagtgttat cttttaattt tctaccctta
     1681 ccctagcatc tctattgccc gtagtatgca tactttccat gtttgcgaaa ataatgttta
     1741 tctagtaaat attgcgggat ttcacatata ttggggttga tcagctcgtt ttctttggcc
     1801 atcagacaaa tttcatctaa gatcaaactg ttttctactg ctttcatagg tgaatccccc
     1861 catgtgaacg gtccatgtcc atagacaagt actccaggga cttcgtttgg atctaatttt
     1921 ctttccttaa acgtctcgac aatcacattc cctgtatgaa cttcgtaagc ttctcttact
     1981 tcttctttcg ttaattggcg tgtacaagga accttaccat aaaaagcatc agcatgagtc
     2041 gtgccataag ctggcaaatc gcgtcctgct tgcgcccaca tgacggagtg cgtggaatga
     2101 gtatgagtaa tagcagttat atcttcaaaa gtttgataca aaacaacatg tgtggggaga
     2161 tctgaagatg gttttaagct atcttcttct attatatttc ccgacaaatc tgttaccacc
     2221 atttgatctg cttgcatgca ttcatatctg acaccgcttg gcttaatgac gatgactcct
     2281 agctcacggt ccacttcact cacattgccc caagtcaatt tgactaatcc gtatcgcggc
     2341 aatgccagat ttgcttcaag gacacgttgc ttcattgctg caattttttc ttcacaagac
     2401 atcatagcca gcctccttca atttagaact taagtagtct tttgcctgct ggatttctct
     2461 tcgaaagtct tggctttttt cactccacat ttcaatcaga aatgttccat cataatctag
     2521 acgtttcaaa tgtcttaata atccaagaaa atcaacacaa ccgctaccaa aaggaacatc
     2581 acgaaactgg cctgaatatt cttttgttac agggtaagta tcttttaagt ggatagcagt
     2641 gatataatcg atccctttct caagttctcg agccggatta ttttccggcc atgcggacaa
     2701 attgcctagg tctggatata cttgtagaaa aggtgaatga atctgttctt tgatttctaa
     2761 aaattttgaa atggagttca taaatggatc atccatgatt tccacggaaa gaatgatgcc
     2821 atatttagaa gcttccttta cgctttcttt tattccttcg ataaagtctt ctctggaatt
     2881 cattgatttc tcttcataat aaacatcgta tccagctatt tggattactt tgacgcttag
     2941 attatgcgcc aaatggattg cttttttcat tagttgtttc gctgcttttt tcttttctgg
     3001 atcagcagaa ccaaacggaa atcgccgatg cgcacttaaa caaatcgaat ggatacgtac
     3061 accggagctg aacatctctt ctctcagctc agctatcttt tcttcagacc aatctaatcg
     3121 tgctaaccgc tcatccgtct catcaatcga catctcgata aaatcgaagt ccatttcttt
     3181 tacaagggaa aaacgttctt tccatgaaat atctttgggt aacgcttttt cataaatccc
     3241 aatttgagcc atttccttac ccccagatac gaatgatctc atctttgaag ttttgtgcgg
     3301 ccttcatcgg atcatttgct gctgtaatac cacgaccagt gataaaggta tacacatcga
     3361 tcccttcaaa taagtgtaat gtgtgtggat ttaatccacc agttacagaa acattaaagc
     3421 ctagttcaat cagttttttg atcttcgata aatctttttc accccaagtt tcaccagata
     3481 acagcgcatc acggctttga tggtagatta cctgccggat accgatgtta tgccaatcca
     3541 tggcttgttc aaaagtccaa ttgccgtaga gttctacttg caattcacct atttcttttt
     3601 gtgctgcctc catagttgga atcgttgcac aacaaatgac tgtcatccag tctgctcctg
     3661 cttttgcaac attactcgcc actgttcctc cagcgtctgc acatttcgta tcagcgacta
     3721 gttttttatc tgggaacata ctgcgaatac agcgaatcgc tttttgtcct tcctgtaagc
     3781 aaagaattgt gcccacttca ataatatcta ctacatcacc aactttcata acatctccta
     3841 atgcatgttc taagtcattg tgatctaacg caatttgcaa attcggcctg ctcatcttag
     3901 ttccttcctt tacttgtttt tttggtacca ctttgtttca gcaaattttt cactgatttc
     3961 tttgactgac atcacatttt tgataccgat aactgtaact ccttttttct ctgcctgagt
     4021 aaacatattc aaaaaattga ctggcgtaaa aactacatcg tattggccag ctgaactttt
     4081 tccctctgaa atggcacaat gatggatttt ggtaattggt acgtttagtt ctttcattgc
     4141 tttttccaca cttctcatca tcatcaagct tgttcctgat ccatttgcac acgatactaa
     4201 aattctcatc ttaatccctc cattatgagt gttgtctaat cagattttct tttatactct
     4261 ctgcttttct gcatatgtgt catagtcttc tacaatcaaa aaataaccat caggattttt
     4321 ccgatattgt aactgcggaa tagccaataa accaatgaca actacggcaa ttccagcata
     4381 acctaggact ttcatgatta ctgtaaacaa tggccaagct gttgcccagt cgaacatccc
     4441 gatataacca ccgtatgttg acatcccaat ccatgtagcg aataatgctg aaccgcctac
     4501 ttgtatgatt cctgaaagaa acgggaacag gcaagcggct ttgaatccac ctcggttatt
     4561 ggcataaact gctataacgg cattatcaaa gaacaacgga atgaaaccgg ctatgacgat
     4621 cgttggtgat ttcaataaaa tcagtaaacc aatcatcaaa aactgtccca aagcaccaaa
     4681 caagaaccca atcgttaccg catttggcga accaaagcca aaagtagcag ctacgtcaat
     4741 tcctggaaca gctcctggta aaatcgtgtt tgagattcct tggaaagatt gagttagttc
     4801 atcgacgaat gtccgaacac ctaattgcaa gatcgccaga tataccgcaa aatttaaaga
     4861 agtcgtcata atgtagaata agaaactctg cccttcttgc atgaattgcg cttgaatcaa
     4921 ataatctttg cctagtacaa tcagaatgat cccaaagaaa aatagcatga gtaacgaagt
     4981 agcaaccata ttctcattga aaatcgacaa gaatcctggt aatttgatat cttcaatttt
     5041 tttgtcttgc ttgattgatc tatttttctt ttcatcccgc tttttcatcc actcagctaa
     5101 ttttgcaaat ataaagattc cgaacatttg ctgatgtgcc actgcaaatc cggcaccttc
     5161 tgtcaattcc tgcgtgattc ctactgttaa gttagaagct actgcccaat aacaacctaa
     5221 aatcagtccc ataaaaatca atacttgtat cctacctaga tcaggaaagc aaaacagtaa
     5281 aatccaaaaa gcggtagctg cttgttgaac ctgaacgttt ccggtagtga aaacggaacg
     5341 cagtttcgta tatttctgaa aacggactaa taagatattt aaaacaaatg caatcagtaa
     5401 taaaatcatc acatctccaa aggtacggcc aaatgtctcc attaatccag catccacagc
     5461 attttgtcca aaataaggat ctgtaaccat ggcatccaaa ttgaaccgtt cctttagtcc
     5521 aaccaagatt ggccgaaaat tattgaccaa accaccagag ccaacagtca aaataaagta
     5581 accgaccgtt gcctttaaga atccagcgat gcattcatga agcgggcgtt tcagcaaaat
     5641 atagcctaat aacacgataa aaccaatcag gtatgctggc tgcgtcaaga tatttgttgc
     5701 aaaatacgtc caaatgctta acaaaaattc ccccatcttt tttctcctct atcaattaat
     5761 tatattctgc catcacaact tggtaatcat cgatggagtt cgtagagatg agacgctcaa
     5821 ccaatccatc tgtcattaat aattcggata atttttggat attttctaga tgttcttctg
     5881 gatcttttgc tgcgagtgta aaaaacaaac tagccgtttt ctcctcattc tccccttcac
     5941 tttcaaaacg gattggctgt ttcaacttgg taaatgaaat agctgttcca aaaacaccat
     6001 cacttttttc tgaagaatgc ggcattgcta cttgaggtgc gatcacaata taaggaccgt
     6061 atttttctac acaatggatg atctcctcca catacgtttc atcaataatt tccttatcga
     6121 tcaatacaag acagctttcg gcgatagctt cacgccaatc cgtgatttct ttatctgggt
     6181 aatgaatcaa ttgatggtca aaaaagtatt tcagcaagaa actccccttc tttcttataa
     6241 aaacgacgga aacggtgtat cattttcaat cgagaagaca tcttcaaatc ctcgataaaa
     6301 attaaactca agatcatctt tgtttgtcgg atagatgaat ttcccgccta cttgccagat
     6361 ataaggttta aatccatact tcaggcgatc ctttttgaat ttccaaattt cagtgatctc
     6421 ttttggatca gccataaaat tagaccaaat atcgtagtgg acaggaatca ctacttttgc
     6481 attcaatgac tccgccatgc gcagcatatc aacagaagta actttgtctg ttatccctcg
     6541 tgggttttca ccataggccc ctaaacagac atcgattttg tgttcattac catgtttggc
     6601 aaataaattg gagtaatgtg aatctcctgc atgataaaga ttccctcctg atgtttcgaa
     6661 taaatagttt actgcaattt gatccatctc ctgaggcatt tttcctttta atacctcttc
     6721 tggatcttca caagtgacca acgctgtccg atcaaacgct tctaaagcta ctacattgat
     6781 gtctttgatt ttgactgcat cacctggctt tactgtaatc gttttttctt caggaattcc
     6841 ccatttttgc cacgtgcgaa ccacttcttt tggcccaatg aatgttgctt caggacaatt
     6901 ttgatgaact gctgcggctg tatggatatc tagatgatcg gaatggatat gtgtaacgat
     6961 taaagcgtct acatttttta tcgcaaaagg atcgattacg aaaggctgag tacgtaaatt
     7021 aggctgcata ttttgaacgc cactcatacg catcatctga tggccttttt tcatcatgcc
     7081 attcccatga ctacgttttc ccgtcccaca ccatagatca cataaaatat tcgttccttc
     7141 atgacttttc agccaaattc ccgtacagcc cagccaccac atagcaaaag ttccaggatc
     7201 cactacttct gtttcgattt cttcattcaa gtatgtgccc cactcaggaa atgtttctac
     7261 taaccacttt tcttttgtta cttcattgac agttttactc atttgcttgc tccccccata
     7321 tcgttgttcc aacttacaag taaatattaa tgtgtatcag catccatgaa aaccctttta
     7381 tatgaccgtt tgttttttat atgattttct ttcagtaatc aatgattgtt tcagtataat
     7441 aaagacagat atgaatgttt aaatgaacaa ctagtcaaat aaatccatgg atcaagatgt
     7501 ccctcaggag gcaaaagtca tgaaaaactc acttgtcaat attgaaaaac gtcaaaaaga
     7561 aattttggaa ctgcttcagc agactgaaca actatcaact ttcgaattag ctgaatccct
     7621 tgatgtatct attagtacga tacgaagaga tttaaattta ttagaagaaa aaaacgagat
     7681 catacgcaat tacggttatt gttcttataa ttacaaaaac cagactgatt ttgatcaatc
     7741 tggtcctgaa aggattaaac aagcgattgc cagagaagct agtaaataca ttaacgatta
     7801 tgatacgctg tttatcaatt ctagctcgac tgcgttgaaa acactggatt ttcttcaatc
     7861 taaccatttg acagtcatta caaacaacgt gaaaatcaat tactctccgc acaaagataa
     7921 ttgtagttat attttaactg gtggagagat gcgctttcca aaagaagcac tagtgggcga
     7981 catcgcatta aatacgattt cttcagtcaa tgcagacatt tgtatcattg gctgtagcgg
     8041 agtcgatgta gtacatgggg tcacaacaaa gatattaaat gaatcaacga tcaacgaaat
     8101 gatggtcaac aagacaatca aatgtaagat tttagtcgct gatcatcgaa aaatcggact
     8161 gacatcaaag ttcaagattg ctgatatttc agtctttgat tatttgatca ctgataaatt
     8221 ttgttctgaa aaagtattag aggagatcag aaatacgggg ataaaaacca ttcaagtaga
     8281 ttcattttaa gaaccaggac gtaaatatgt aaataggatt atcaaaaaaa tgaataacaa
     8341 atttatcgat aaatgaaaaa cacgctacgc tcaaattgat aaaggaatcc caagatgtat
     8401 ccatccaatc gataccatca taatctattg cttcttttat aaccgttata tgttgcctaa
     8461 ataggaatca aacaatatcg aaaaaaggag gtatgacaaa agtcacacct ccttttttcg
     8521 aataaacggt attcaaatca gaacactgat ttcacaacca ctttatttca ggtcgttttc
     8581 aatcaccttt accgcgtaat catttccgtt gaaacgcgct attttttttg cgtccatata
     8641 tctttctaaa taatcatctt ctcctaattg cttatggcaa gaagcaattt cataaagcaa
     8701 gtattccaat gcataagtcg atttatgttt cttattatac tcaataccct tctcacataa
     8761 ttggattgct ttatcataat cctcgatttt acggtaatag gtggcgatat cataatatac
     8821 aatgcagacc atcagattat caaaatcagt ctcactcaat attttaagtg tacgctccac
     8881 ataaactttc gcaaaatcta attctccttt tgacaagtag atcattgcca cgtttgcagc
     8941 tgcttgtaag tgatggatat ctgtttcggt cgtttgttcc aacacttgat taaaataaaa
     9001 taatgctgca tctggttttt tcgcataaag atgatcaagc agtccttgat aaaataaaat
     9061 ttgatttaaa agatcagaat tacttacttt ttcctgatcg atcgtttgta aaattttata
     9121 agattcttgg tattttgata cagaattcaa tgattgaatc tcatttattt ttttcctgat
     9181 tttgtcttct tctgtttcta ctaatatatc ggagatctcg acattcagct ttttgcaaag
     9241 cgcacttaag atattgatgc ctggcgacat attcttgttt tcgatattgc tgacagttgc
     9301 ttgttcacaa atgccttctg ctaattgtac ttgtgttaac ccctttttct ttcggtattc
     9361 ttttagtaat gctccatcta ctttaatcaa aacaatttcc ttccctttaa aaaattattt
     9421 ctcctttata tcatacacaa aaaaaagttc taaacaacca aaaatgttta gaacagaata
     9481 aaaattttaa ttttaaaata atattcaaat taaacaactg gcgtatctgc tccttgattt
     9541 ctttttgtgt tatctgaata attatcgttt acagttataa cacatagtga aaattgtcat
     9601 ggcgagaaag tctaagaata tttttaaaca taactatttc tttcttacgt gtgtataatg
     9661 acgacagcac acctatcaat taatataatt attttatttt tttatgttct catgtttatt
     9721 tttaatgaca caacttctcg tatttatctg gcacaacata taaatcgatc aaaaaattgt
     9781 tgcgtgtttt tttgaaaatt ggagtttcaa cttgattaca aaatttaaat ttagaagttg
     9841 tgaaaacagc gagagacagt ttaatattca aaatatacat aggctactcg aacgctgtgt
     9901 tttttagtat actagtaaga aacgaaggga tagactcatt ccaataagga ggatttcatg
     9961 aagacaattc tttttgctcc tgcagtattc aatttagctg agacaacacg aatgattgag
    10021 gttgccaaag ctatgaaaga ccgttattac tgtgtattct ttggcttttc taaaactttt
    10081 gctcctttga tcacagaaag tggctttgag tatcatttac tagcgccgat ccttacgaaa
    10141 aaacaagaag aacaaatcat aaaatttgac cagttgcgta cacttaaaaa cccttttacc
    10201 aaagaaatgg ttgcctctcg tatcactagt gaacagagtc tgattgctaa gtttgagcct
    10261 cgactgattg tgacaggttc gaatgtgaca atttttttat cggcccgcaa taaaaagatt
    10321 cctttagtat atgttaaacc ctatgctttg agtgaacctt tttttcaatc agagcatgcg
    10381 ctgatgcccc acgagttacg tttcttcggc cctttaagca atcccctttg gcactggaca
    10441 aaaaagcgta tagtaaatac ccgatggatc cccaatgcct tcaaacacgc tgcacaaaaa
    10501 gaaatgcttc ctttaccaaa aacaagttta caaatgatgg atgctgatct aaatctcatc
    10561 acaacgccta aactattttt ggaagaagaa cagctgccgg aaaattatcg aatcgttggt
    10621 ccaatttttg ctaagctcag tacttccttg cctgaagaag tgctaacttt tatacagcga
    10681 aagcaacaag aaagaaaacg tattatctat ttcgcaatgg gtagttcagg caatccgcgt
    10741 atgttacgca aaattttgtt cttcttacaa aaacaaccgg atctagcggt tattgcacct
    10801 attgactatc tgcttgatga cattcaatct gactcagaag atcttttaat aacagaatat
    10861 ctgtctagtc atcttttgca tgaattcatt gatttttctt ttatccacgg cggggaaggg
    10921 accgtccaaa ctgcctgtga atccggcaaa ccgtttatcg gtgtggggat gcaatttgag
    10981 caaagctgta atattgacta ttgtgtaaaa tacggaaacg caatcgccct cacaaaacca
    11041 gtgactgaaa gaaaactgca gattgctctg cgcgaagttt cttcacccaa gattcgtcag
    11101 caggcacgca cgctgcaagc cgtttttcca ataaatggtc cacaacaagc aattcaagaa
    11161 atcgaaacct tcctgagcaa ccacccaata tagtttcaag tagaaaaagc ttttttaata
    11221 gagactcatc agtaatttcg ctattcgaga cccagacagt gaaaatacaa aaaaagtaaa
    11281 tagtggattg aaaagttaga gttacttaaa ttacggtgtc taaaaaacac aaaatcatcc
    11341 ttaaaataaa agatctgacg ctatccaaat gagcataggt agcgtctgcc atttattctt
    11401 agtcaaattc tttgacacct ttctctggtt ggatcatctc aacgtttctt caaaagaaag
    11461 accataataa ttaggcaaat acattttctt aaaatgtgtc atatagatct agaagcatcg
    11521 ctttgtagag atttgtgccg ctagtcccct caacaattac taaatcaaat gtaggattta
    11581 ccactttatc tttgataatc aacctccctc ttctgttgag acaatgatct cgcaatccga
    11641 tgcatactcc tatataaact gccagcaatc cccacatatt gagtagatca tgtcagaatg
    11701 ttctatgtcg tcagcaacga tacactaaaa gtcacgttca ccatgactga ttgctattcc
    11761 cagcacaatt atttctatac acgtttcatg atttgaataa acactcacat catacatatt
    11821 accattcata caccatactg cagcccctac tatatggttg taagctccca aatctatatt
    11881 tgacttgatc actttggtag tagatctact aattctaaat ccattgctga taaaatttcc
    11941 attttttcct ccttctttct gccaaaacag ttaaaacaat aataatcttt atgtaaaaaa
    12001 gggctgtgac aaaagccttg tcacagtccc atattccgaa taaacggtgg tcaaaagctt
    12061 gcatctgcgg taataagttc aaccaaacga aaaataagcc aacatttcac aaaaatttaa
    12121 gaagcaattt tcgtaaattt cttcttattt cttgaagcta accacttctg ttacaaccac
    12181 ttttagaaca tttaaagctt cgatgtgaca aaccatctat gctgctcgat cataaaattg
    12241 atagcaaaaa ttccacaaag tacatatgtc ccccatgaaa acaaaacatt caaatgcgtt
    12301 acaatgatct ttggaagaat cacgatcaaa aatgatgcca gtgcccaaat ccatcgattg
    12361 atttgaatat gatatgtagc tagcatattc aatataaggt gactagccgt taataaaaag
    12421 ataaaaacaa aaaataaaat cagccaatac attgtttccc accttctaaa aaccaaactt
    12481 agacagtctg gacttcgttt tctccacgac tttgttcatc tgacagcatc tttttatcat
    12541 aagcttttac aaatggataa tagataataa atgctatcaa tgtgttgatc atgatcaaga
    12601 taacaacacg ccagtcattt cctgctgaaa gataaccgcc gattggagct ggtaatgtcc
    12661 atgttggcaa aacagtaaat ctattgacca tttctaattt gactgcaaaa taactgataa
    12721 tagtcaaaac taaaggaact aagttgaacg ggatgaacat gtaaggattc aacatcatag
    12781 gagctccaaa aattatgggc tcattgatat tgaagatacc aggaataata gaaaaacgac
    12841 caacctcttt caagaatttt gatttacaga agaatataaa caaaacagat accacgatcg
    12901 ttgctcctgc accaccaatt gttaccgtcc attgataaaa ctgttcagga gcgatatagg
    12961 gtaattgggt ggcagctgta ccatctgcca atgcctttgc attctcatcc aacatgatca
    13021 gccacattgg acgaacgaca gcccctacaa tactcatgcc atggatacca aatgaccaca
    13081 acaaatggat caaaaacatt ggtagtaaaa caccaagcaa attattccct aaaatattgg
    13141 ttaaaggctc gaataacgat aataaggcag cgtttacatc aaagcccgcg acgcttcgaa
    13201 tcagccaagt aattgttaaa atgactgcac ctggaatcaa tgcctcaaaa ctacgggcaa
    13261 cagcaggtgg cacttgttct ggcattttga tagtaatatt tcgattttta aagaaacgat
    13321 atacttccac tgcaaaaatc atagataaga tccccgcaaa catcccagat gctcccaaag
    13381 aactcatagg taagacccag ccaagaggtg cctcttcagg agttaaaacg tttacaggaa
    13441 cttgtaacat aaagaacgtt cctaaagata atataccacc tgtcacacta tctaatccat
    13501 atgatttagc tagatccgaa cccataacaa aagttgcata aatagccatc aatcccatcg
    13561 tcatcctaaa gggtaaaaca atcgttgccg aataaggggc aataaattca ttccatccag
    13621 gaaacggtaa attgataaag accataaaaa atgtcccaat caaaatcaat gacaatgttg
    13681 aaacaacccc attacgaatt gctaataaat gacgctgtgt accaattttt gccattggtg
    13741 ggacaagttt ctcttcgacc catttcatca gcttttccac taaaaccact ccttttcaat
    13801 aaaatatgaa ccattcattg catgacaacg caaagaatgt tcataactaa ttatataatt
    13861 aagaaatttt atttcaatat attctcttaa ataatcaaat ttatttttaa gaatcctgaa
    13921 aataagtttt ctaaatcata ggagcaacaa aaaaattcga taattaacaa aaatcaaaat
    13981 gattaaatct agtgattgaa acatatcatt tcaaaaaaat tttgtaaatt cacccataaa
    14041 tatcacccta tttaactttt ttcatcgtac actaaaattc aaaacaacta tctttaatct
    14101 ttacttcttg gttttgtttt aataaatttc cttcaaaaat gcctggagaa actacaatga
    14161 tcaccgtatc tttttgtgct tgctccaact tcttcaaatc tataatagct aacagtgtcc
    14221 cttcttttac ctcctggtta ctttcaaccc gtatctgaaa cggacttcct tcgagttcaa
    14281 ctgtatctaa acccatatgg atcagtattt ttctgccaga ttcactttcg atcgttatgg
    14341 catgtcgggt aggaaatata ttatcgatta ttcctttaac tggcgcatgg atatatccat
    14401 catgattcgt tatagcgtat ccaactccta tcatttttga agaaaagacc tcgtctttta
    14461 ctgctgttaa tggaataatt tgaccactag ctacagcttt tagaatgttt cttgttttaa
    14521 agaaatgcac tttttatcac ctctacttta atgctggcca atattttttg tttactttga
    14581 tcatttcatc tagtattttt tttgcgactc tggcatttgg tacggtttga ttcaatgtaa
    14641 atgcttgtaa agctttttga taagaacctt caaagtaagc atctactagt aacttctcta
    14701 ctgcaacttg tgcctccatc aatcctttat gaaaatcact gattggtttt cttagtgtaa
    14761 ttggctccac accagttgca ccaacatatg ccggtatttc aacaactgca tctgaccgta
    14821 gattcggaat cgccccttga ttaggaacga ttagcataaa gcgacgacga tcatcattca
    14881 acaaggaaat agctatatcg acgatatatt gtccatgctc cccaaaatta aagttcaata
    14941 cttcttccac aataccgcgg cgtattttat cagccatttc tttggtattt ttctctcgtc
    15001 catccatgac catattagca cgtgtatact ctttgtcagt atgctcaacg accatatcag
    15061 gatataagta atactctaag taattattcg ggatattact tggaaaattt ttcgtgatga
    15121 ctgacatcat ttgaaaggtt ttttgccaag ttttatctcc tatattaaaa tcggcgactt
    15181 gcatttcttt tgttattagt ttttcaataa tctctggcat aatttctcgt tgcaattctt
    15241 tat
//
LOCUS       DADQCX010000070        14715 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.070, whole genome shotgun sequence.
ACCESSION   DADQCX010000070 DADQCX010000000
VERSION     DADQCX010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.070"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(146..1111)
                     /locus_tag="J8R83_001990"
     CDS             complement(146..1111)
                     /locus_tag="J8R83_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAZ9575119.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            1345..2190
                     /locus_tag="J8R83_001991"
     CDS             1345..2190
                     /locus_tag="J8R83_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9575120.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            2381..3568
                     /locus_tag="J8R83_001992"
     CDS             2381..3568
                     /locus_tag="J8R83_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAZ9575121.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            3574..3930
                     /locus_tag="J8R83_001993"
     CDS             3574..3930
                     /locus_tag="J8R83_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAZ9575122.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            3932..4270
                     /locus_tag="J8R83_001994"
     CDS             3932..4270
                     /locus_tag="J8R83_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAZ9575123.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            4665..5699
                     /locus_tag="J8R83_001995"
     CDS             4665..5699
                     /locus_tag="J8R83_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9575124.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            5692..6378
                     /locus_tag="J8R83_001996"
     CDS             5692..6378
                     /locus_tag="J8R83_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575125.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            6402..7250
                     /locus_tag="J8R83_001997"
     CDS             6402..7250
                     /locus_tag="J8R83_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9575126.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            7447..8220
                     /gene="sufC"
                     /locus_tag="J8R83_001998"
     CDS             7447..8220
                     /gene="sufC"
                     /locus_tag="J8R83_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAZ9575127.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            8233..9519
                     /gene="sufD"
                     /locus_tag="J8R83_001999"
     CDS             8233..9519
                     /gene="sufD"
                     /locus_tag="J8R83_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAZ9575128.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            9516..10751
                     /locus_tag="J8R83_002000"
     CDS             9516..10751
                     /locus_tag="J8R83_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAZ9575129.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            10738..11208
                     /locus_tag="J8R83_002001"
     CDS             10738..11208
                     /locus_tag="J8R83_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAZ9575130.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            11213..12604
                     /gene="sufB"
                     /locus_tag="J8R83_002002"
     CDS             11213..12604
                     /gene="sufB"
                     /locus_tag="J8R83_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAZ9575131.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(12702..13844)
                     /locus_tag="J8R83_002003"
     CDS             complement(12702..13844)
                     /locus_tag="J8R83_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9575132.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(13895..14692)
                     /locus_tag="J8R83_002004"
     CDS             complement(13895..14692)
                     /locus_tag="J8R83_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575133.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
BASE COUNT         4754 a         2692 c         3125 g         4144 t
ORIGIN      
        1 ttacgacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccag
       61 tacaaaaaca tgaacagctg tttttgtttg gccgttctta ttacttgatg cagaacagct
      121 ttttcacaac ctattgaatc gattattaag cgattttttt agaaacaaat tttccatgtt
      181 tgctatgttc tttaattaag aaacgtacgt aatgagcaag aacgtagaag acaactacac
      241 ttgcaaacag acattccgca acttttaaga aatccaatac gctactatag atacctaaac
      301 tgttgaagta atgaacagta gtaaatatag ctgttgcaga gataacaagc gggaatgtaa
      361 aggctgcata gcttggataa aaacgaagct tgaacaaacg tggaagcata gacagcacaa
      421 cgaaatacaa tacttgagat aaagcgaaca atgctacgac aagataaaaa ttaggttcag
      481 caaagttttt aagataacct gttaggcaaa gagaaccagg tgctgcaacg atcgtaatca
      541 gcggacgtgt cggatgagcc atatttctta cgaaaaagac acgtttgatg atgatcggca
      601 ataagaacgc atagcagatc aatgaaatcc aaaagaaaat ttttccaata agtgggaaga
      661 agttcccggc agttacagtg atgaccccaa atccaacgta aatgataaac cagcttggat
      721 aaattgcttc aattgaaaga tcagctttga taacatggtg ataattgaaa taaaagacaa
      781 ggatcacttg gaagataaca gcgcacagcc aaatgaattt gacaattggt gcaatacttt
      841 catatgaaac aaaataagta caaataacca tgagtgacat cgtaaaagtt ggtgaaacgg
      901 aggcgatgat tggatcatgc aacgtttgtt tcgtgtgttc gaataagata aacaatttaa
      961 caaaaatgaa tatcataaga atcatagaga taccgccagt tagattgcct aaagcaacat
     1021 ggtgatagtc tttaaacaga tttccaaggg aagctaaccc aaggatcaac ccgcagatcg
     1081 ggatcggaat aattttcaaa aagttcttca tatataatat tctccttttt atttaataga
     1141 ttttagtacc aagatgaacg aatacattgt aaaatgaata ggaatgtatg attacgagca
     1201 agcagacagc tgattgtctt catctaagtt actagttgga tcagcaactg ttttgttgta
     1261 catttctatt atagatggtt ttttgtatat ttaaatcaaa tagtttttat agtaattatc
     1321 ataaaaagtt atggaagtgg tgccatgttt aagttattaa cgacttttcg agcagtatat
     1381 gaaacaagaa atttttccag agcagcagaa gtactgtttt tatctcaacc agcagtctcg
     1441 aatcaaatca aacagttgga gcgggaattg aatatcgatc tttttcaacg taacggaaga
     1501 aaagagatgc ttccaactaa gcaagccgac ttattatatg aacggacact ggttttgtta
     1561 gaagaatggg aagaaactca gcaaaaattg ctcaatgaac aaaatgaaga agaagtatgt
     1621 cggatcgttg cttcccacac ctttgctgtc tatcttttgc ctcagttgat gaaacatctg
     1681 atcaaaaggt ttcctaaagt gcattttgag atcgaaatca cgaattctca tgaatcatta
     1741 gaacaagtag cgaaacatga atccgatttt ggttttatcg aaaagccatt agagacttcc
     1801 ggcgtacaaa gatactcttt gatggaagac cagctagtca tcgctgggga cccaaaaagc
     1861 aaattgtggc ttgtaagaga agcaaactct ggtgtttttc attacacgca gcgttatttt
     1921 gaagagatga atatccaaga taagaagatg atcgtgaaaa gtaacgatgt aattgttgcg
     1981 ttgctgaagg aaggaatcgg tcgctcgatt ttgtctaagc gctctgttcc agaaaatgtg
     2041 ccaatgactc cgttgaattt ccatcgatat ttttatttca tccaacgaac caatctggtt
     2101 tctgatcagc tgctagagat tgccgaagag atccttcgat acaatgaaag cacagaaact
     2161 tctcacagcg aggagaatct cagctggtag ataattgcat gtatcaaaaa aagttctatg
     2221 atacactaaa gataagcagt aggcttttgt actgcatttg ctcaagcaac tgcacaaacg
     2281 gaaagttaat ttttcccaaa tgtctatgga aagactttcc attatctaac tggaccgcta
     2341 taataatcag cagtatggtt tttaagaaaa gggatgaaac atggaaaaaa aattaaaagc
     2401 ttcgaacgat aatcgtattg attatggcgt gattttacca gtctttctgt tatgtttgat
     2461 tggtctgctc tcattatatg tagcacttag ccatgatccg aacaatccag cagtcttgaa
     2521 aggcgtaggg atgcaagttg tctggtattt agttggagcg gcagcaatcg ttgtcatcat
     2581 gcatttgaat tccaaatgga tctggaaact gactccttac ctttatggtt tggggttagt
     2641 ggtaatggga ctcttgctca aattctatga tcagaattta gctgcttcaa cagggtctaa
     2701 aaactggttt cgattcggtg cgtttacttt ccagccagca gagttgatga agattgcgta
     2761 catcttgatg atggcactga tcgtaactaa acataatacg caagtaaaag aacggacgat
     2821 gaaatcggac ttttggctga ttgggaagct cttgatcgtg acaataccgg ttttagcatt
     2881 gatcatggcc caagatgact ttggaacgat gcttgtcttt cttgcgatct ttggcgggat
     2941 tttcctgatg tctggaatct cttggcgcat catcgcacct gtagtaatct tggcagtagt
     3001 cgttggagca ggaacgatct tcttggttac gactgaaggc ggaagagact tgctttataa
     3061 agttggattc aaatcttatc agtttgcacg tattgattca tggctggacc ctttccatga
     3121 tacgtcagga atgagttatc agccggccca aggacttttg gcaattggta ccggtggctt
     3181 gtttggtaaa ggattcaacg taagcaatat ctatgtgcct gttcgtgagt ccgatatgat
     3241 ttttaccgtt atcggtgaaa acttcggctt tatcggtggt gcattcgtca ttttcttgta
     3301 ttttatttta atctatcgta tgattcgggt gtgtttcgat acgaataatg aattttacgc
     3361 ctatatcgca agcggtttga tcatgatgct gctgttccat gtctttgaga atattggagc
     3421 aaatatcgga ttacttcctt taacagggat cccattgcct ttcattagtc agggaggatc
     3481 ctcgatttta gggaacatga tcggtatcgg gttgatatta tcgatgagat accaaaatga
     3541 agcacctgca agatcttcaa ggaggtaaga aaattgtaca ccttttactg gtacccgaaa
     3601 tgttcaacat gcaaaaaagc caaagcgtgg ttagaccagc atggcgttag ttatcaaacc
     3661 gttgatatga tcaaagaagt accgaaggcc tcaacgattg agacttggct agaaacgagt
     3721 caagtaccaa tccgtcgcct gttcaacaca agcgggatga aatatcggga acttggactg
     3781 aaagatcaag taggcgagtt tacggcttca aaagcgagcc aagtcttatc gacagatggt
     3841 atgctgatca agcgaccact gatcttacga gaggaccagc ttgttgcaat tggattcaat
     3901 gaaaaaattt atgaaggaga actgatataa aatggcaggc aagcatttga agaaaaagga
     3961 caacctttgg atcttattta atggaaaaga atactgtgtt ggtttgacaa atgaagcgca
     4021 agaagaactt ggagacatca cgtttgccaa tctgccaaaa gcaggacaat cgctaaaaaa
     4081 agatgaacct ctgatcgaag ttgaagcgga aaaagcggtc aatgaatttg ccagcccgct
     4141 aacgggtaca gtttcttctg ttaatgataa aatcggtgaa gatatcaata tcttgaatga
     4201 ttcagatgaa atgaatgcgt ggatcttaag tttcaaagat gttgatccaa aagaatttga
     4261 cgaattataa aatcagaaaa tcacttgaaa aaagttgaca ctgattcttc cagttgctat
     4321 aatcataagc aatcctatat gaaacgagaa agctttgaaa agaagagtac atgtcacgga
     4381 cgtttgaaga gagccctgtt tgctgaaaat gggtaacgaa aatgagatgg aagatggtct
     4441 tagagcagag taagcgagcg taagcaaact tactacggga gtgcccgtta cagcgcgaca
     4501 gtatacggaa agaagctaag tccaagtact ggaagaggct gttattgcga agtaacggta
     4561 aatcaaggtg gtaacacgga agttcaagct ttcgtccttt tgcttaaggc aagagggcga
     4621 aggctttttt gtttgaaaaa ttataagaga aagatgtgaa tggcatgtca ttaatccaac
     4681 taacgaatgt caaaaagaca ttcaatggga aaaacggaaa catccaagcc gtcaatgacg
     4741 tttcactaaa cgttgaaaaa ggggatattt atggaatcgt cggctattct ggcgcaggaa
     4801 aaagtacatt agtccgtctc ctgaatggac ttgagcttcc cacgagcggc gaagtgatcg
     4861 taaacgatca agatattaca aaattaaaaa acaaagaatt acgtacattc cgaaagaaaa
     4921 tcggtatgat cttccagcat ttcaacctgt tatggtcaag aactgtactt gaaaatatcc
     4981 agctgccgct ggaattagct ggcgtaccaa agagcaaacg taaagaacgg gcagaagaac
     5041 tgttgcgttt agtcgggtta gaaggacgcg gacaagcata tccttcacaa ctttccggcg
     5101 gacagaaaca acgcgtcggt atcgcacgag cattggcaaa tgatcctgag atcctgcttt
     5161 gtgatgaggc tactagcgca ttggacccgc aaacaacaga agaagtatta gacttattgt
     5221 tagcgatcaa taagaaattg aatttgacca tcgtcttgat cacacatgaa atgaatgtga
     5281 tccgcaaaat ctgcaacaaa gtcgctgtga tggagttggg gaaagtcgta gaagaaggag
     5341 acgtattgac tgtcttcaga caaccgaaaa aagaagtaac caaacgcttt gtacaacaag
     5401 acatcgaacc agaagctgat tcgacagaac tattagctga actcatcaaa gaaaatccaa
     5461 gcggccgttt ggcaactttg acctttagcg aaagaaatgc caacgagcca gtcatttccc
     5521 aagcgattcg acgctataac atcgatgtca acgttgtgta tggaaagatc aaacaagtga
     5581 aagaaggttc ctttggttca ttgactgtct tgatgactgg tgaaaccaaa gaattagatc
     5641 aagcagaagt gttcatcaaa gaacaaggag taggaattga ggtgatccat cgtggataaa
     5701 agcttttcag aaacatatct agattttaaa caaatcaacc cggaaacgat gaatcaggct
     5761 atccttgata cactatatat gacattaatc tcaatggtct tagtgacgat catcggatta
     5821 gttttgggat tgatccttta ctctattgga cgcaaaaaca aaccgtatgc tcgaatcatt
     5881 tatggaatcg tatcgatcat cagtaatatt ttccggtcaa cgccatttat gatcctgatg
     5941 gttttgatca ttccatttac taaagcaatc gtaggcacta tgctaggtgc gcaagcagcc
     6001 attccagctc ttgttttatc cgcagcacca ttttatgccc gtctagtaga gattgctttt
     6061 cgtgaagtca gccctggtgt actggaagca gcagatgcaa tgggagcaag ttactgggaa
     6121 atcatctgga aggtcttgat acctgaaagt attcccgcat tgatttctgg attaacagtt
     6181 acaacgatct cgatgatcgg atttactgcg atggccggcg cgatcggcgc aggtggactt
     6241 ggaggtcttg cttggcagga aggctaccag cgtggtaatc taacagtgac attcgttgcg
     6301 actttaatta ttttactaat cgtatttatc gttcaaggaa tcggtgattt cttaactaag
     6361 aaaacagaca aaagataata ggatataggg ggatgtagga tatgaaaaag aaaatttttg
     6421 gatttgcagc agcgcttttg ctgactgtag gattagcagc atgcggtaac aacagcgaca
     6481 gcaaagattc agcaaataaa gcagacgaca cgacattgaa agtcggcgct tcaccgacac
     6541 cgcacgcaga gattttggaa catgtgaaac cattattgaa agatgaagga atcgatcttg
     6601 aaatcgtcaa attcgatgac tatgtattac cgaaccaatc tttggaagaa ggcgacattg
     6661 atgccaatta cttccagcat attccttatt tgaacaaaga aatcaaagaa aaaggatatg
     6721 actttgtcaa tgccggtgct gtccacatcg aaccaatggg cttgtactct aaaaaagtca
     6781 aagatgtttc cgaattaaaa gatggtgcaa caatcattac ttcaaattct gaatcagact
     6841 ggggacgcat catcacaatt ctacaagatg ctggcttagt caaagtcaaa gatggagtag
     6901 atctggaaac agcaacattc gatgatattg aagaaaaccc taagaacttg aagttcaacc
     6961 atacgatcga cccatcactt ttagcttcta cgtaccaaaa tgatgaaggt gacctagttg
     7021 caatcaacgc aaacttcgct tacggcgcag ggttgaatcc attagaagat gccgtattgc
     7081 ttgaaaagga caactctcct tacgtgaata ttattgcgac tcgtaaaggt gatgaagaca
     7141 gtgacaaaat caaaaaactg attgaagtgc ttcaccgcaa agaagtccaa gaatggatca
     7201 cagacaaatg gggcggctct gttaaaccag taaaggctga tgcaaaataa ggtatggaac
     7261 aaaaaagatg agaaataagt ctgtaatggc ttatttctca tcttttttat acctattcta
     7321 atttagaaat caaaattgtt taataataaa taaaagatat ttgattttag taaggaaggt
     7381 cattgcgctt cattctcaat tagtctaaaa tgagtgagaa cgaaagagaa tttgggggta
     7441 taatgcatgt ctgtcttaga aataaaaaat ctacatgtgt cgatcgagga aaaagaaatc
     7501 cttaaaggcg taaacctaac aatgaaaacc ggagaaatcc atgccatcat gggacctaac
     7561 ggcacaggaa aatctacctt atctgccgct atcatgggca atccaaacta tgaagtaaca
     7621 gaaggcgaaa ttttgtttga cgggaaaaat gttttagact tggaagtaga tgaacgtgcg
     7681 cgacttggct tatttttagc tatgcaatat ccaagtgaga taccaggtat cacgaatgcg
     7741 gaattcatgc gtgcagcgat caatgcgaaa cgtgatgaaa acgacaaaat ttctgttatg
     7801 gcatttttga aaaagttaga tgaaaaaatg gctttactaa atatgccaga agaaatggct
     7861 gaacgttatc tgaacgaagg tttttctggc ggagaaaaga aacggaatga gatcctgcaa
     7921 ttgttgatgt tagaacctac atttgcaatt ttagacgaaa tcgattcagg tctggatatc
     7981 gatgctttga aagtcgttgc taaaggagta aatgaaatgc gcggagacaa tttcggtgca
     8041 ttgatcatca cccactatca acgattattg aactatatca cacctgatgt cgttcacatc
     8101 atgatggaag gccgagtagt catgacaggg aatgctgacc tagctaaacg tctggaagca
     8161 gaaggctacg ctggtatcag taaagaatta ggaatcgact ataaagaaga agaagcgtaa
     8221 gggggagcaa gaatgaaaga aaaaaactgg ctcgattatc ttgacgcggt aaatgatttt
     8281 tctttaagta aaggcgaacc tgattggatg agaaccttcc gtcaagacgc actagcgaaa
     8341 gcagatgaac tgccattgcc gcatatcgat cgggtgaaat tccatcgctg gtcgttattt
     8401 gatgtgaaag aaacacaaac catcagtgaa acaggcacga ttccggcatt tgatgcaatg
     8461 aaagacaatc ctgtgcttgt ccaacaaggt tcatggacga tttttgaaca actgcctgtg
     8521 gaattagcag aaaaaggagt catttttacc gacttgttca ctgcaatgat cgaatatcca
     8581 gaactagtcc aagaatatta tatgaaaaaa gcagtaaaca tgaacgaaga ccaattgact
     8641 gcactccatg tagcttttat gaacagcggt attttcctgt atgtgcctaa aaatgtcgtg
     8701 atcgatgaac cactcgagtc cttattcatt caagatggcg catccgatga gcacttcttc
     8761 aagcatgtgt tgatcgtggc agatgaacat agtgaatttt cttatctgga acgtttccag
     8821 acaaccaaag aacaagtagc aaaatcatca ggtaatatca tcgtggaagt catcgctaaa
     8881 gctggttcaa aaatcaaata ttcagccgta gatcaattag gagaaaatat tacttcttat
     8941 atgaatcgcc gtgggcacat tttacgagat gcttctgtcg actgggcaat tggtgtcatg
     9001 aatgacggtc atgtgatcgc tgactttgac tcagatttag caggagaagg tgcacacgca
     9061 gaagtcaaaa tcgtggcaat cagctcgggc agacaaatcc aaggaatcga tacacgagta
     9121 accaataaag cccctcatac gatcgggcat attttgcaac acggagtgat ccgagaaaaa
     9181 ggaacattga cctttaatgg tatcggccac atcttgaaag gggcaaaagg tgcagatgcc
     9241 caacaagaaa gtcgtgtctt gatgctttct gataaagcac gtggtgatgc gaatcctatt
     9301 cttttgatcg atgaaaacga agtaactgct ggacatgctg ccagtgtagg acgagttgat
     9361 ccagaagaaa tgtactatct gatgagtaga ggattgcata aagaagaagc agagcgctta
     9421 gtgattcgag gattcctcgg ttctgtctta acagcaatcc ctgtagaaca agttcggaaa
     9481 gaattagtcg aagtaatcga agggaagttg aatggatgat cgatgctaaa aagctacgca
     9541 atgattttcc tatcttattt caagacgtca atgatgaacc tttagtttat ctggataatg
     9601 cagcgacgac ccaaaagcca aaacaagtac tccaggcatt agcgtactat tacgaacacg
     9661 ataacgccaa tgttcatcgc ggtgtccata cgttagcaga acgcgcgacc catgattatg
     9721 aacaagcaag agaaaaagta cgggcgttca tccatgcaaa agaaacagca gaagtgctgt
     9781 ttactcgtgg tacgacgaca agcttgaatt gggtagccag aaccttcggc gaccgctata
     9841 tcaaagcagg agacgagata gtgctctctt acatggaaca tcattctaat gttatcccgt
     9901 ggcagcagtt ggcaaaacga acaggtgctg tcttgaaata tatcgaacta acagaagaag
     9961 gcttcctgga tatggaggat gcagcgaaaa agattacgga caaaaccaaa atcgtctcca
    10021 ttgctcatgt atccaatgtc ttaggtgtct tcaatcctgt tcaagaatta gctgaacttg
    10081 tccatgaaaa cggcggggtc atcgtagtag atggtgctca atctgccccg cacatggcca
    10141 ttgatgtcca agcactagac tgtgatttct ttgctttcag cggacacaaa atgtgcggac
    10201 caacaggtat tggtgtttta tatggtaaac gaaaatggtt agaagaaatg gaacctgttg
    10261 aatttggtgg cgaaatgatc gattttgtcg aattatacga cagtacatgg aaagaactac
    10321 cttggaaatt cgaagcaggg acaccaaata tcgccggcgc tatcgcatta ggccatgcaa
    10381 tcgattattt gcaaaaactc ggtatggaca atatccatcg atatgaagaa gaactagccg
    10441 cttatgtgtt gccaaaatta caagcaattg atggattgac tgtttatggt ccacaagacc
    10501 cgaattttcg gacaggagtc gttgcattca atttggatgg gttacatccc catgatgtcg
    10561 cgacagcttt agacatggaa ggggtagccg tcagagcagg tcatcattgt gcgcaaccgc
    10621 tattgaagta ccttgaagta tcagcgactg ctcgcgcgag cttttatttc tacaacacaa
    10681 cgcaagacgc cgaccgttta gttgaagcaa tcatggcaac aaaggagttt ttccaacatg
    10741 ggactatcta aattagacaa tttataccgt caagtgatct tggatcattc ttcccatccg
    10801 catcatcgtg gaagcttgac tgactcgaca agcaagatcg aattgaacaa ccccacatgt
    10861 ggagatgtga tcgaattgca agtcgatgta aaagacggaa tcatcaaaaa tatcgccttt
    10921 gacggcagtg gctgctccat cagtacggca agtgcctcga tgatgacaga cgccgtcatc
    10981 ggaaaatcaa tagaagaagc agaacattta actgtagact ttctacagct tgtccaagga
    11041 aaagaagtca aagatcccga ccaattaggc gatgctgcta tgcttggtgg tgtagctaaa
    11101 tttcccgctc ggatcaaatg tgcgacactt gcctggaaag cactaggaaa agcaatggaa
    11161 aacgatggta ccgcagcttt ccatcattac cacaaggaag aggagtgaga acatgggcgt
    11221 accagaatta gaagaatata aattcgggtt tcacgatgat gtcgaaccgg ttttcagtac
    11281 aggagaaggc ttgacagaag aagtgatccg tgagatgtca agaatcaaag gcgaaccaga
    11341 atggatgctt gaattccgtc tgaaatctct agaaacattt aacaaaatgc caatgcaaac
    11401 atggggcccc gacctttcag acatcgattt cgatgccatc aaatattacc aaaaaccaag
    11461 tgacaaaccc gctcgtgact gggaagacgt accagaaaaa atcaaagata catttgaaaa
    11521 gattggtata ccagaagctg aacgagctta tctagccggt gcttccgcac aatatgaatc
    11581 agaagtcgtg taccataata tgaaagatga attcgaaaag ttaggaatcg tctttactga
    11641 cactgactct gctttgaaag aataccctga attattcaaa gagtactttt caaaacttgt
    11701 accgccaacc gacaacaaat tagcagcgct gaattcagcc gtatggtcag gtgggacctt
    11761 tatttacgtg ccaaaaggcg tcaaagtcga tgttccatta caaacgtact tccggatcaa
    11821 tgcggaaaac acggggcaat tcgaacgtac gctgatcatt gttgacgaag gagcaagcat
    11881 ccactatgtc gaaggttgta cggcacctac ttattcaagt aacagcctgc atgccgccat
    11941 cgtagaaatc tttacaagaa aagatgcgta ttgccgttac acaacgatcc aaaactggtc
    12001 agacaatgtg tacaacttag taaccaaacg agcaaaagca tacgaaggcg caaccgttga
    12061 atggatcgac ggaaacctag gtgcaaaaac aacgatgaaa tacccaagtg tttacttaga
    12121 tggaaaaggt gcacgaggca ccatgctctc catcgccttt gcaggagcaa accaaatcca
    12181 agatacgggt gcaaaaatga tccacaatgc accaaataca tctagctcta tcgtctctaa
    12241 atcaatttca aaagacggcg gagaagtaaa ctatcgagga caagtaacct ttgccaaaaa
    12301 cagtgcgggt tcgatctctc atatcgaatg tgacacgatc atcatggacg aatggtcgaa
    12361 atccgatacg atcccattca atgagatcca caacagccaa gtctctttag aacacgaagc
    12421 caaagtctca aaaatctcag aagaacaact ctactatctg atgagccgag gcctgaccga
    12481 atctgaagca actgaaatga tcgtcatggg ctttgttgaa ccattcacca aagaacttcc
    12541 aatggaatat gcagtcgaac tcaatcgatt gatcagttat gagatggaag ggtctgtagg
    12601 ttaataacta tttcattgct cgaaacgttg atattaaagc gtttcgagcg tttttttatt
    12661 tgtattttaa tggttggcta cgtttttggc tacgtttgga attattcgcc cataaatttt
    12721 gcaaatcggt caccagtttt cttaacagat tgtggtgtga catgagcata gatattcatg
    12781 gtagttttaa tatctttatg acctaatcgt tcctgtactt cttttatcga cgcaccactt
    12841 tcaaacaata agctacagtg ggtatgccta aatccatgtg gagtaatttg aggctccatc
    12901 ggtgtctttt tgtaaatcca gtctaaccaa tcgtttacta cttgggggta gtacaacttg
    12961 tttgtgtttg tagtgaaaag aaactgtttt ggtgaattcg tgttatagcc atataagatc
    13021 attattttca tttgttcttg ttgccaaata cgcagttgtt taagtgtaaa atcatcaagc
    13081 tgaatcgttc ttgatgaatt tttagtttta ggtacttgta gaactacttg attaaactcg
    13141 tcttgagcga tagttttacc aattgttatt gttttattga aatagtctat atcttcccat
    13201 tgaagcgcca atgcttcgct tttacgcatt cctgtataag ctaataaacg gaaaaaagtg
    13261 tacagtttaa ctgaattatt ttctttagta ttctgtaaaa acagttgtaa ttgatctttc
    13321 gtgtaaaact tcaagggttg ttcttcttca atttttcttg gaagcaatgt tttagacata
    13381 ggattatcct tacagacttc cattgctact ccaaatttaa atatttgagc agttgttttt
    13441 ctcaagaaac catattgttt taatgttttg tgccattcat tcacctgttt ttggcaatag
    13501 ctaacactta ttttatccaa tcgtaattcc ccaaaagcag gtaatatatg gtttttgcaa
    13561 aaacgttgag caacggcaac agaagacggt tttactcttg ttctgtagtt atcaatccat
    13621 aattcataca actcttgaaa agttgtaaca ttgattttaa actcttgttt ttctttaaag
    13681 tctacaagta gtctattaag tgctgtttgc gcctcagctt ttgatttgaa tcttctacgc
    13741 tttgtacgta tatcttttcc agtcttggga tctttcccta aataagtttc aaatccccaa
    13801 tatttttcgc cattttgtaa tttataacta aaaaatgttg ccatttgatt ctctccttac
    13861 ttcattattg caggtagaga agttatttga agaatcaatt atttttaaat ttatcgtgat
    13921 tatcagttaa aaattttgcg attatactat ttttctcata tgggaaattg tattttttac
    13981 taagatctga aataaatttt tctgtttcaa attggttttt agtaatttta taaaagaaat
    14041 cctcgacaga tgaatacttt gaaatatctt tataggctaa gtccatttcg tctaatagct
    14101 gttttaaaga atcaatcatt ctttcttttt caccgtattt gaaatcacca tttcttatct
    14161 tgtcttgaag tttactgttg gctcttttga aaaatagctc tttagagata gagtgtcttt
    14221 ggttagcgta ctcttcaatc agaggattga tattattagc aagtatctca tttagataaa
    14281 tttcaaaatc ttttgagtaa tattttgtaa atatattttt tattatagga ttcaataact
    14341 catagtcttt atctagcgaa aacgtatcac tatatctttc ttgaatgtct ttaaagactt
    14401 tgtgaggtat ttctgggaag tccttaatat atagctcata ccctatatcg ataaggtatg
    14461 aagttatata ttcttctaaa gttccccatt taatccagtc aattgttgaa ttagtgatag
    14521 ttgataataa tttcagcttt tgtggatttg gtaaattggt cccacgttcc cagttggata
    14581 tggtcgcacg tggtgaatta tctattttcc ttccaagttc ttccatagta aaaccacatg
    14641 aaaggcgtaa ttgtttgatt cgttttcctg cttctgaagg atttggcttc atcttttttc
    14701 tcctttttat tttta
//
LOCUS       DADQCX010000071        14026 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.071, whole genome shotgun sequence.
ACCESSION   DADQCX010000071 DADQCX010000000
VERSION     DADQCX010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.071"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            807..1007
                     /locus_tag="J8R83_002005"
                     /pseudo
     CDS             807..1007
                     /locus_tag="J8R83_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1494..1673
                     /locus_tag="J8R83_002006"
     CDS             1494..1673
                     /locus_tag="J8R83_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575134.1"
                     /translation="MTELTADMSDTWLQEYLFPEKQTTARGYLPVDWEYVHKELMKKN
                     MTLKLLHREYGVHGT"
     gene            complement(1719..2324)
                     /locus_tag="J8R83_002007"
     CDS             complement(1719..2324)
                     /locus_tag="J8R83_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575135.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2506..2841
                     /locus_tag="J8R83_002008"
                     /pseudo
     CDS             2506..2841
                     /locus_tag="J8R83_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3006..3233
                     /locus_tag="J8R83_002009"
                     /pseudo
     CDS             3006..3233
                     /locus_tag="J8R83_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3359..4330
                     /locus_tag="J8R83_002010"
     CDS             3359..4330
                     /locus_tag="J8R83_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9575136.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4470..5783
                     /locus_tag="J8R83_002011"
     CDS             4470..5783
                     /locus_tag="J8R83_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAZ9575137.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5826..6692
                     /locus_tag="J8R83_002012"
     CDS             5826..6692
                     /locus_tag="J8R83_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9575138.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6689..7537
                     /locus_tag="J8R83_002013"
     CDS             6689..7537
                     /locus_tag="J8R83_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9575139.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7551..9023
                     /locus_tag="J8R83_002014"
     CDS             7551..9023
                     /locus_tag="J8R83_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAZ9575140.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQKRIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            9040..9912
                     /locus_tag="J8R83_002015"
     CDS             9040..9912
                     /locus_tag="J8R83_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9575141.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(10146..11527)
                     /locus_tag="J8R83_002016"
                     /pseudo
     CDS             complement(10146..11527)
                     /locus_tag="J8R83_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11817..12422
                     /locus_tag="J8R83_002017"
     CDS             11817..12422
                     /locus_tag="J8R83_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAZ9575142.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            12438..13010
                     /locus_tag="J8R83_002018"
     CDS             12438..13010
                     /locus_tag="J8R83_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575143.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(13483..>14026)
                     /locus_tag="J8R83_002019"
     CDS             complement(13483..>14026)
                     /locus_tag="J8R83_002019"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9575144.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
BASE COUNT         4387 a         2370 c         2833 g         4436 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgcc atttaaaaag aaaagtgaca
      361 gataggaata aaaacttatt aaatgtagtt atgatctgtt atatttcatt tctaatacta
      421 ggtcttccac aagcagtgtt tcctgaaatg ttttctggag actggggtat tgtcagctat
      481 tctatattaa cattgattgc tatggtttta ggtacttcat tttataatgc ttttgtaagt
      541 aagcatgttg aggaatatga agtattaatg tacttaaaag agaaaaaaac aagtaattaa
      601 tatgagaaca ccacgcatag tttttatttt gagatattct agaatgaaac acattaagaa
      661 cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc taagtttttt catatttgtt
      721 tgttatgcta tacatagatc tgcataatta gacttgcgct gcccgttatt gaagtttcag
      781 gcagcgctct ttttggggga tcgataatgg aagaagaaaa aatatttgag aaacgctggc
      841 agctagcatc aagtgaacaa agagcaagat acaataattt gatcacctcc taccccactg
      901 ttgactagac atataaggaa aagaaatact tactttggct gtgccagtta gatatagata
      961 cctttgaaac atttgaagtg atcctagata aaattaaaca gaattgatca gaaacaagcg
     1021 aagccttctc tcggttcgct tgttttgcta tttattagtt ggctcagggc aactctaagc
     1081 tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta ccactttaga atacatggat
     1141 gtacgtattg ccattgactc ctattagtta ctgaaaaaaa atttaaacaa gttgagtatt
     1201 gcagataaat agctccagtg aggtgaataa ctgctccact caaggcaata gatagctcca
     1261 tccagggcaa caaactgctc cactttcata tttaatagat gaataacctt ctgtataata
     1321 gaaaggcata cctttcggta tgacaactta tacagaatgt tattttattg gttcactatc
     1381 gaaaaatttt ggagctttat ttttccggta tttctcaacg aacgattagt ttaactgtgg
     1441 gaagctccag acatacgatt cgagaagtta cttctcgagc agacaggaag ggggtgactg
     1501 aactaaccgc tgatatgagc gatacttggc tgcaggaata tctttttccg gaaaaacaaa
     1561 caacagcacg aggttacctt cctgtagact gggaatatgt tcataaagaa ctaatgaaaa
     1621 agaatatgac attgaaactc cttcatagag aatatggggt acatggaaca tagaaacgaa
     1681 aatgcacggt agaaaagcga atgaatatag tataaattct acaaatcatt cgctttcttt
     1741 attttatata tggttggtcg agagagacca ttttctttgg caatttctgc aactggaact
     1801 ccttgattta acatgtccac cacagtttta aagactaatc gtttttgcgg atctgttgag
     1861 ttctcagaat attcaattgg tcgcccctta tatcgaccag cttttttggc caataatact
     1921 ccttgccgct gacgttcacg gattttctca cgttcgtttt gtgcaatata acttagcaat
     1981 gataaaaaca tatcgaacat agcagtatct aggagttcat ttccagtatt aaaatctaaa
     2041 aactgtgcat ctagtatttt taatgctact tttttctgtt tcataaaggt aactgtattt
     2101 tttatgtctt cataatctct gcctaggcga tccagtgatg caacaatgac acaatcacct
     2161 tctcggatat aatttagtaa tttttgaaac tcaggtcgct ggatatcttt accactggct
     2221 ttttcttgga ataatttatc aatgttaagg tcttccatca ttgccaattg tcgatctaaa
     2281 ttttgatctt gtgaagacac tctaatatat ccaatttttg ccataaaaac tccttttaaa
     2341 aaatgatata atttacatgt aaaatttact tgtagtttta ctgttatcat agcattttta
     2401 aaaataaatt ttaagtctac ttataattta ctttggaggt tttgaatgaa tgaaattaag
     2461 cgcaataaaa attcttttgg tgtttattta ggagagccta gctcggaaca gttaaataaa
     2521 ggtgaagctc gtcatgctct atgtcgaaat atattttatg gtagaaaagg caaactttat
     2581 caaacttatt acgacggtat ggaggaacag ctcaacgcat taggattagt aactaatgct
     2641 atcatatatt ggaattcact atatttagaa aaagtctttg aacaaattaa aacggaaggg
     2701 ttcgactgtt ccgaagaagt gttacgcaag caatttccat taattagtga tcacattaat
     2761 tttgttggca aatatagttt ccgctatgaa aaagaattat cgaatggaat actacgtccg
     2821 ttaaatatag agaattattg agaatgttcg tcttttggtt cctaccgtgc attttcgcac
     2881 ggatgttcca gatactattt ttgaatgtat aaaattgaaa acacaagaat actaataaat
     2941 caacgattct tgtgttttta atttttcact accgtgcatt ttcgtttcta tgttccatgt
     3001 accccaatct tgaaaaatta attaaagact tagataaagc cattgacgac ttagtcgtgg
     3061 tgctaccgga gtatcaatgt ttaaccagta tcccaggtat tggtcctgtt taggctgctg
     3121 gaatactcgc tgaaattggt ccaattgaac gtttttctga tgaaataaaa ttgacaaagt
     3181 atgccggcct atattggcga cagagtcaat ccggtaaatc tgaatacgaa aattttttta
     3241 cgaaaagctt cacgtctaat atctatttta aaataaaaat attcctgcta atttggaatc
     3301 gtttccttct tttggtataa taatacctga aattcttttg agaggagttg ttcgtgaagt
     3361 gaaaactact atgaaggatg ttgctgcgtt agcaggagtt ggtgtgggta cggtatctag
     3421 agtaataaat ggagtaaagg tgaaagaggt taccaaagaa aaagtaatgg ctgcaattag
     3481 tgagcttaat tatgagcctg atgaatatgc cagaggtatg aaaacgaata gtagcaatac
     3541 aatagctctt attttaccta cgatttggca tcccttcttt tccgagtttg cctactatgt
     3601 agaggaagct ctcagccaaa aaaattataa gctttttttg tgtaatgcga acggcagtgc
     3661 ggaaaaagaa aaagaatata tccaaatggt caagcagagt aaagtagacg gaattatagg
     3721 tattacctat tcagacattg ataaatatgt atcatcaaat ttaccatttg tcagtataga
     3781 ccgccatttt tcggaacagg tttcttatgt aacggcagat aattatttag gtgggcaaat
     3841 tgccgctcaa gaactactta ctcgtaactg taaaaacttg tgctatgttg ggggtgtttc
     3901 accttaccct aacgaaacaa acaatcgtaa agctggtttt tacaatattt gtgaggaaaa
     3961 taaaatagct gtgaaggtat tggatatgcc tgaaccaatt agcaatttag aggaacaatt
     4021 gctcgctttt ttttcggata atcctgaaat tgatagcatt tttaccatca atgatttcat
     4081 ggctttggat gtgataaaag cccaaaaaaa actagggaag gaagcaccta aggattttca
     4141 aattattggt tttgatggag tcaagctatc gttgcaaaaa gactatttac tatcaacgat
     4201 tgtacagccg atagaggaaa tggccaaggt ttcagtagaa acactcatgg cgatgatttt
     4261 aaatgaagaa ccgcctaagc gtgtggtagt accggttttc tttcacgctg gagagacgac
     4321 taaagagtaa aaaaccggtt tataacgatt tttttgagat aggttgacag aaagtgattt
     4381 caatgatatc ttaaaaccaa ttaattggaa acgttaccaa ttaattgaaa aataaaacgg
     4441 aaacgtttca aaaaatagga ggaacatcga tgaaaaagag aatgttagca attgcagcaa
     4501 ttttagcatt aacagctgga ggacttgcag gatgtggcag taaggagaaa agttcaggta
     4561 gcagtgatcc aggagaaatt aagatttggg ttcagttttc tgatgaaacg cctgaaggaa
     4621 aagcttgggc agagattgtg aacaatttta atgatgaata cgagggtgaa tataaagctg
     4681 ttactgagta tattcctcgt agcggaagcg gcggtggata tgaggataaa gtaaatgctg
     4741 caattacaac caataccctt cctgatgtta ttacgttaga tggaccgaat actgcagctt
     4801 atgctcattc aggagtcatt gctccattag atgattattt gaaagatgcg gacatggatg
     4861 atgtattaga cagcattatt cagcaaggaa cctacgatgg caaaatgtat gcgtttggtt
     4921 tctcagagtc cagtgtgggt gtctattaca ataagtcgct gttcaaagat gctggaatta
     4981 cagaagatca attgccgacg ttagaagatc cttggacttg gacggaattt caagcaattt
     5041 gccaaaagct gactgataaa tacaaaacgc ctgcaattga tatgcaaatg gcgtcgggag
     5101 acgaaatgct gacctacgca tatacaccat ttatatggtc gaatggcggc gatgtcgtta
     5161 atgctgatgg aaccaaagcc gaagactatt ttaacggtaa aaaatccgtt gaagcgttgg
     5221 aatttattca agaattggtt gaaaaaggtt acaccacaat cagtcctatt gaaaaaggat
     5281 ttgaaactgg caaatatgcc atgatgctga gcggttcttg gacaatggca gatttagagg
     5341 aaaactatca agagattgat tatggtattt tgccttaccc cgtttcagat gcaactgggg
     5401 agttagtttc accaaccgga agctggcagt tagcaatgac tgagaaaaca gagaaaaagg
     5461 atgcttctgc ggcctttatt aagtttgcaa ccagtacaga atctagtcgt attatgagtt
     5521 tagggaacag tgttctacct atcagaaatt caacagttga tttaattaaa gatgaagtgt
     5581 cggaaggaat gcaggtatta attaagcaaa accaactttc tggacatgcc cgcccagtgg
     5641 ttgtagctta tccgcaagta tctagagcat tccaacaagc agttcaagat attagctact
     5701 tcgaggaaaa cccagatgta caaaaagtag cagatagtcg cgctgctgaa atgcaacagg
     5761 caattgatac ttcactaaaa tagaagtttc taaagggggc caatcaagtg ttaaaaaaac
     5821 cgacaatgaa agacaatttg ataggttacg gctttctagc gccagctttg ctgctgctga
     5881 cgatttttct gatcataccc gtaatcatgg taatttatta tgcctttact gattattatt
     5941 tgttaacgcc agatgctaga caatttatcg gcttagaaaa ttttaagcga ctgttcgctg
     6001 atccaatttt tgtaaaaagt atttggaaca cggctaaatt tgttgtttgg attattccgg
     6061 tccaaatagg ggcagcttta ggaatggcac ttattatcaa caaaaatcgt aaaggaaata
     6121 tcttttttaa agtagccttt tttgcgccag tcgtgatgtc cttagtcgtt atttcgattt
     6181 tatggttgta cttgttaaat cctaatgaag gtctggttaa tacgctattt gcaaagattg
     6241 gaattgcttc gcagcctttt ttgactagtc ccaaacaagc aatgtatacg cttgttttcg
     6301 tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt tttaggggga atgcaaaata
     6361 ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt ttctaagttt cagcaatttc
     6421 gctatatcac catgccatta ttaaagccca cggcgatttt tattttactt accacattga
     6481 tttcggcctt taaactaatc attcagccaa tggtaatgac tcaaggtgga ccaatgaatt
     6541 ctactatgac aatggtttat tacatttacc aaactggatt tacagaccgt atggtaggct
     6601 actccagctc cattgcgtta atctttacca ctatgattgg tttaattaca attgctcaaa
     6661 gaaaattggt aaaggaggat gatccagcat gaccaagaaa tttggaccgc taatgatcgt
     6721 agaatattgt ttgctgttcc ttttagcggc attattcatt ttcccgatgc tgtggatggt
     6781 agtttcctct atgaagcctg aagcagatgt ctatcaaaat ttagcttcct tcaaagcttt
     6841 tttacctagt ttgaatccag ctaattggtt taaaacttat caagaggtta tttcccggtt
     6901 cagtgtggga acttatttat taaacagtat tttttatggt ttaacctttg cctgtgggtc
     6961 aatcattgta aactctttgg cgggttttgc ctttgcgaag gttaattttt caggcaagaa
     7021 aattatcttt ggagctttgt tagctctgct gattgtcccg atggagacgg ttttaattcc
     7081 gcaatttacc atcgttaatt cactaggctt agtgaatact cgcttggcag tgattttacc
     7141 agcgatggcc agcgcgttta atatctatct gtttagaaat ttctttatcg cgattccaga
     7201 agaaatcatt gaatcagcga aattagatgg tgcaaatatt gttaaaattt tctttcacat
     7261 catgctgcca atgtctaaac cagccatagc cacagtaggt gtcttatcct ttatctccag
     7321 ctggaatgat tatatttggc cgttaatggt cttaactgac agcagcaaat tttcaatgca
     7381 agtggcaatt actacgatca atactacaca gccagtttat atcaatcaag tgatggctgt
     7441 tttaaccatt gcaacgattc cactgattat tgtttatatc gttgcacaaa aatatattct
     7501 gcagggactt ggcggttctg gaacgggtat aaaataggag tgaatagtga atgttgcaaa
     7561 aacttttaaa ggccaatgag tttattgaga aaaatgctca aacagtcaat caagaatacc
     7621 ggaataaatt tcatttgatg gctccgattg gctggatgaa tgatccaaat ggttttgttt
     7681 attatcaaga ggagtatcac ttgttttatc aatattatcc ttacgacagc atctggggac
     7741 caatgcattg gggccatgct aaaagcaagg atctaattca ctgggagcat ttgccagtag
     7801 cactggcacc aggtgaaagc tatgacaagg aaggctgttt ttccggcagt gccatagaaa
     7861 aggatggcaa gctgtatttg atttatacag gacacaatgt tgtggaaggg caagttcgac
     7921 aagttcagtg tttggcagtt tcagaagatg gcattcactt tgaaaaatat gccggaaatc
     7981 caatcatcgc agaagatcac ttagcttctg ttgcaacgac cgaagatttc cgcgatccca
     8041 aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc tactaaaact gcagatgctc
     8101 gtggacaaat tgtgatgttc cattccaaag atttactaac ttgggagttt tattccgtat
     8161 tgctggaggg aactccagaa caaggcattg tatgggaatg cccagacttg tttgaactag
     8221 atggcaaaga agtcttgatt ctttctccta ttcaaatgac tccacaaggc aatgcttacc
     8281 aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga ttggcaaaca ggcaaatttc
     8341 tagtagagaa ttttcatgaa atcgatggcg gtttagattt ttatgcaccc cagacctgtg
     8401 aaaacgaagc aggccaaaga ataatgattg cttggatgca aatgtggcag cgtaaaatac
     8461 ctacgaatga tctgggccat ggttggtcag gttccatgac cttgcctaga gagctgaggg
     8521 tggctgataa tcaattgttg caacggccag tttcatcaat ttatcaagta attgatccgc
     8581 agaaaaggat tgaatgggcg aagactgaag agaatcgctt cttactgaag gacttagtat
     8641 atgaccagca ctatttacgc ttggaaatca atttaaaaca ggcaacgaaa ctagaacttc
     8701 actatgcgaa gggacccgac catacattac tgcttaacta tgatgttgaa cgggagtgct
     8761 ttactgcttc cagggaacac atgccgtatg atttatcagg agctgaaaag gaagtgttga
     8821 aaaagcgcag tgtgacgatt cctttggaaa ataattgtct aaccatcgaa attttccgtg
     8881 atacttcagc tattgagctt tttctaaatg atcgtctgac tatgagtaca actttttatg
     8941 agacagaaaa aggacaggat tttcttttgc tggcagacag tgaagtaacc ttttcattgg
     9001 aaagcggctt aattaatcta tagaagggag agctcagtga tgatttatgg ttcaatcgaa
     9061 gcaggcggca caaaatttgt gtgtgccatt ggcgatgaag aaatgacgat caaggaaaga
     9121 gtgagctttc cgacaacgac acctgaggaa acaatacctt tagtcattga cttcttcaaa
     9181 caataccaag cagatttagc agggattggg attggctcat ttgggcctat cgatatccat
     9241 cgcgattccg ccacttatgg gtacattacc tcgaccccga aagtggcatg gcaaaatttt
     9301 gatttcatcg gtaccatgaa aaaagaattt ccgatcccga tttcttggac aacagatgtc
     9361 aatgcggctg cctatggtga gtatgtcttc ggcagtggca aaggattgag cagtgtcgtt
     9421 tactatacga tcggtacggg tgttggcggc ggtgccttac aagaagggcg ctttatcgaa
     9481 gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc ctcatccaaa agatgacttt
     9541 gctggcagct gtccatttca tggcaactgt ttagaaggga tggccgctgg acccgccatc
     9601 gaaaaacgct tagggaaaaa aggacaagag gttgcagaag atgatcctta ttgggaaatc
     9661 gaagcctcct atattgctca atgtgcctac aatacaacct tgatgttttc tccagatgtg
     9721 atcatttttg gcggtggtgt gatgaaacaa cgccatatgc tgcaaaacgt ccacgacgca
     9781 tttgcaaaat tggtcaatgg gtatgtcgaa acacctgagt taagcaaata tatcgtgacc
     9841 ccagcattag aagacaacgc tggaacgctc ggttgtttgg cattggctcg agaagcggtc
     9901 ttacattcat aaacgaaaaa aggctcttcg acatttagtg ttggtagaga aagatacaac
     9961 tgaaaattta gtcataacca gttaggcaga gtgcttaact ggtttttgtt ttacttggaa
    10021 gatcaagcct tgaatgagat aagttcttgc tcgaaagtta tggaaatttc gatagccgta
    10081 ggccacttgt attgtgcaat agttttttac aaaaaaaggg ggtgcggata tttttttgga
    10141 cctttttaac aaatatatct ttgcttcttc cgatattgaa gagggcttag ccctcctaaa
    10201 gataacttaa ttcgttgatt attataccaa tgaatataat catccaattt gtttataaac
    10261 tgattgattg ttgtattctt ccagtcacgt tgataaaaca tctcgttttt taatcgtcca
    10321 aagaaacctt cgcacgctga attatctggt gaataaccct ttttagacat agagtgaagc
    10381 aagttggctt tgttccaata gtccaactaa caatagcacc atcgtaacaa tcgacaagtg
    10441 gtgataagta gattttccct gcgggaattc taaattcagt aatatctgtt aaccattttt
    10501 catttggctt ctttgcttta aaattccgat ttaataaatt ggggtgtgca ggagaaattt
    10561 ccccagcata cgaagaatac ttttttcgtc tagaaaattt aacaaataga ttttcctcag
    10621 tcatcaatct acgtacaact ttttcagaaa gctttttacc catatttttt aaagcttggt
    10681 gaattctacg gtaaccatac gcacagaagt tatgattgaa aatcgtgata attaattgac
    10741 gttctttgta atacttatct ggtttctcaa gtgcttgttt ttgataaaaa tagctgcttt
    10801 taggcaactg gagctgttga agaagctctt tcaaggtgaa ctgatttcgt aaggcatcaa
    10861 tcaatatcgt tttttcttga tttgatagac aaagaagatt gacgcctttt tcttttttta
    10921 gcagttcagc cgctccttcg agtaatgttt tttcgagctg taattggtgt acttgttttt
    10981 gtaagtcttc tacttccttt aaaagtagct ctttttgttt ttcctgattt tttaaagtca
    11041 tacgcaatgg aaaatccttt ccaagaaccg tgtttttcca ttgatataga gtaactctac
    11101 taattccttc agattctgct aaatttttcc tattagtttg cggtttatag aattttttca
    11161 acacagcttc tttttgatct tgtgttaact ttaccgcact ttttcggagt tttctagctc
    11221 ctggtgcaag ttcttcacac cgctgccgca aggactctct attaggataa ccaagcatgc
    11281 gaatggttcg tgcataacat tgaccatatt caaaataatg attcaccgct attcgttttt
    11341 gttcttcaga atactttgat ttttttcggt gctcctgatg gagctctccg gattccaaat
    11401 actctttata ccatttccgt agtgcaccaa tcgacggata ccctaattct cgaatggttg
    11461 cagcataaga gcaatcgtat tttaaaaata actgaattgc ccttacacgc tctttgtggg
    11521 aaaacacacg gacattcctc ctaagtttat tttttcgtcc aggattatgt ccgcaccccc
    11581 ttgctttctg atgacttatt ctggttcttt gagtgtcaat gcatagatgt gatgtagcta
    11641 gttagaaaaa aattttgaat actctttttt tctttcagac tcctttttaa gtaagatttt
    11701 gaagtgtgag ttacggggtc agaaacttaa tagtttttga cacataaaca aaatcgcgat
    11761 ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga tttcgcatga
    11821 ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt gaagaaaaac
    11881 tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa atcgaagttg
    11941 gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt tacgattttg
    12001 ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca ccagttatgt
    12061 atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt gaagagatta
    12121 tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat ggccgaagta
    12181 ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta gattggaact
    12241 taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac gatttggaaa
    12301 tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag ttatatatga
    12361 aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata gatgatttgt
    12421 aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc gcttctcaaa
    12481 gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag aatatttttt
    12541 cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg ttggctggtc
    12601 tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt aacacgagag
    12661 aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag gttttgaatc
    12721 taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg ttgagtgtag
    12781 cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg tttgcaagaa
    12841 agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg aagaagaggc
    12901 acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct ataaccggtt
    12961 tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa aaaagaagtc
    13021 tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat tagcatgttg
    13081 tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta tggtaactgt
    13141 aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat accatcatat
    13201 atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc gtaagtcacg
    13261 tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac tctattgatt
    13321 ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag aaccaaataa
    13381 ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt gtgatattac
    13441 tggatttgag tcaatatctt ggacacattt tagtagagac ggttaagcca ttttttcttt
    13501 tgctaattct tcaaattcct gtggggttag atagtgaatc gagctatgga ttcgatttcg
    13561 gttataaaat ccttcaatgt agctaaatag cgctcgattt gcttcttcaa aatctgagta
    13621 gctagtcgtg tagacttctt cttttttcaa tgaggcatgg aaagattcga ttccagcatt
    13681 atcataaggt gttccttttc tactataaga atgccttatt ttgttggttt taagccattg
    13741 ttccacttct cttgctgtgt attggctgcc caagtcagtg tgtagaatca ttccttctgg
    13801 aatgtgataa tgtatttttg ctttattcaa tgtttgaatg acacaatcca cagtcattcg
    13861 ttttgaaaat gtataactaa taattctttt cgtgtgtaaa tccatgattg aagataagta
    13921 acaccaacca tttttcttag taggaatgta cgtaatgtca gctgcccatt tctcacagat
    13981 cgtttcagta gaaaagtcct gatttaagag attctctttt gaaatg
//
LOCUS       DADQCX010000072        13969 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.072, whole genome shotgun sequence.
ACCESSION   DADQCX010000072 DADQCX010000000
VERSION     DADQCX010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.072"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="J8R83_002020"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="J8R83_002020"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAZ9575145.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="J8R83_002021"
     CDS             complement(2424..2675)
                     /locus_tag="J8R83_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAZ9575146.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="J8R83_002022"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="J8R83_002022"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAZ9575147.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="J8R83_002023"
     CDS             3624..3842
                     /locus_tag="J8R83_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575148.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="J8R83_002024"
     CDS             complement(4130..4642)
                     /locus_tag="J8R83_002024"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAZ9575149.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="J8R83_002025"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="J8R83_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAZ9575150.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7529)
                     /locus_tag="J8R83_002026"
     CDS             complement(7095..7529)
                     /locus_tag="J8R83_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAZ9575151.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="J8R83_002027"
     CDS             complement(7539..8327)
                     /locus_tag="J8R83_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9575152.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /locus_tag="J8R83_002028"
     CDS             complement(8324..9265)
                     /locus_tag="J8R83_002028"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAZ9575153.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="J8R83_002029"
     CDS             complement(9442..10029)
                     /locus_tag="J8R83_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAZ9575154.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="J8R83_002030"
     CDS             complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="J8R83_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAZ9575155.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="J8R83_002031"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="J8R83_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAZ9575156.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="J8R83_002032"
     CDS             complement(12946..13881)
                     /locus_tag="J8R83_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575157.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3856 a         3130 c         2455 g         4528 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DADQCX010000073        13821 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.073, whole genome shotgun sequence.
ACCESSION   DADQCX010000073 DADQCX010000000
VERSION     DADQCX010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.073"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            197..439
                     /gene="yaaA"
                     /locus_tag="J8R83_002033"
     CDS             197..439
                     /gene="yaaA"
                     /locus_tag="J8R83_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAZ9575158.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            426..1550
                     /gene="recF"
                     /locus_tag="J8R83_002034"
     CDS             426..1550
                     /gene="recF"
                     /locus_tag="J8R83_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAZ9575159.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1547..3493
                     /gene="gyrB"
                     /locus_tag="J8R83_002035"
     CDS             1547..3493
                     /gene="gyrB"
                     /locus_tag="J8R83_002035"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAZ9575160.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3513..5984
                     /gene="gyrA"
                     /locus_tag="J8R83_002036"
     CDS             3513..5984
                     /gene="gyrA"
                     /locus_tag="J8R83_002036"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAZ9575161.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6220..6519
                     /locus_tag="J8R83_002037"
     CDS             6220..6519
                     /locus_tag="J8R83_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAZ9575162.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6569..7081
                     /gene="ssb"
                     /locus_tag="J8R83_002038"
     CDS             6569..7081
                     /gene="ssb"
                     /locus_tag="J8R83_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAZ9575163.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            7107..7343
                     /gene="rpsR"
                     /locus_tag="J8R83_002039"
     CDS             7107..7343
                     /gene="rpsR"
                     /locus_tag="J8R83_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAZ9575164.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7486..9459
                     /locus_tag="J8R83_002040"
     CDS             7486..9459
                     /locus_tag="J8R83_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAZ9575165.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9465..9917
                     /gene="rplI"
                     /locus_tag="J8R83_002041"
     CDS             9465..9917
                     /gene="rplI"
                     /locus_tag="J8R83_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAZ9575166.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10191..11558
                     /gene="dnaB"
                     /locus_tag="J8R83_002042"
     CDS             10191..11558
                     /gene="dnaB"
                     /locus_tag="J8R83_002042"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAZ9575167.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12338..13630
                     /locus_tag="J8R83_002043"
     CDS             12338..13630
                     /locus_tag="J8R83_002043"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAZ9575168.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4614 a         2490 c         3030 g         3687 t
ORIGIN      
        1 gaaaagaaat agaaaaaata aaattttaaa cagaaggccc taaaatctct tttaaggctt
       61 tctgtttatt tttgtttaaa tcaccttttt tagattaaat cgtcttatat ggaaaaatat
      121 atggataaat ttgttttatt gcgaaaaaaa aggtataata gagtatactt ttaataatga
      181 aaatgaggga tgggcattga aacaacaagt cattctaaat acggaattca tgacgttggg
      241 ccaaatgttg aaagaagtca cagttatcgg tagtggcgga caagcaaaat ggtatttggc
      301 agaaaacact gtgttagtcg atggcgaacc agaaaatcgt cgtggacgca aactttatcc
      361 cggcatgatg gttgaagttc cagaagtagg aacttttttt atggtaaaaa aaggaaacga
      421 cgataatgag gctgaataag ctgtatttaa aaaattatcg aaattacgaa gagctgaaca
      481 tcgaattttc caagaacctc gtcatctttt taggagaaaa tgcgcaagga aaaacgaatc
      541 ttttggaaag tatctacgta ttagctatga cgcgaagtca tcggacaagt agtgagcagg
      601 aattgattgg ctggactgac gatcaggcga tgattcaagg agagatcaca aaaggttcat
      661 ccactcttcc attagaaatc ttattatcta aaaaaggccg aaaaaccaag atcaaccata
      721 tcgaacagaa aaagttaagt acttacgtgg gacaaatgaa tgtcatttta tttgcaccag
      781 aagatctttc tttagtaaaa ggcagcccgc agatcaggcg gaagttttta gatatggaat
      841 taggccagat caatccaatc tatctttatg atcttgtcca ataccaagca attttgaaac
      901 aaagaaacca gtacttgaag caattgaatg aaaaaaaaca aactgatttg ctttatttgg
      961 atattttgtc cgaacaacta gcagcgtttg gcagcaaagt attgaaagca agagcacagt
     1021 tcgtcaagcg attggagttt tgggctaatt ctttgcatca gcaaatcacc catcaaaaag
     1081 agcagctgga aatcgagtat ctcaccgcag tcgattcttt agaaacacat acgcaagagc
     1141 aaatccaaga acaatttctc gcacttttga accaaaataa aaagaaagac ctttttcggg
     1201 gaacaacgac agttggtcct catcgtgacg atctttcctt ttttattaat cagaaaaatg
     1261 tgcagactta tggatcgcaa ggacagcaaa gaacaactgc actaagtgtc aaattagcag
     1321 aaatcgattt gattaaagaa gagacagggg aatatccaat ccttttgtta gatgatgtga
     1381 tgagcgagct ggatgataat cgtcaactcc atctgctaga aacaatcgaa ggaaaagttc
     1441 aaacgttctt aacaacaacg acacttgacc atgtaaaaaa taaaatgact gttgaacctg
     1501 agatttttta tgttcaacaa gggaaactaa aaggagaaga aactgaatga cagaagaaag
     1561 aagtttagta gaacgcgcta aagagtatga tgccagtcag attcaagtac ttgaaggact
     1621 tgaagccgtt cgtaaacgac ctggcatgta tatcggttcg actagttctg agggtctgca
     1681 tcaccttgtt tgggaaattg tcgataattc gatcgatgaa gtattagcag gttttgcaac
     1741 gaaaatccat gtgattattg aaaaagacaa cagtatcacc gttattgacg acggtcgggg
     1801 gatacctgta gatatccagg caaaaactgg acgtcctgca gttgaaacgg tctttactgt
     1861 tttacatgct ggaggaaaat tcggcggtgg tgggtacaaa gtttctggtg gacttcacgg
     1921 agtaggatct tctgttgtaa acgcgctttc tacacagctt gatgtcaaag tatacaaaga
     1981 aggaaatgtg tactatcaag aatatcgtcg tggagctgta gtggacgact taaagattat
     2041 cgaacaaacg gatcgccatg gaacaacggt tcactttacg ccagaccctg aaatttttac
     2101 agagacaact gagtttgatt tttcaaaatt ggctacccgg atccgtgaac ttgctttctt
     2161 gaaccgcggg atgcgtatat cgattgaaga caaacgagaa gaagaaccag tcatcaatga
     2221 ataccattat gacggcggga tcaaaagtta tgtcgaatac ttgaatgcaa acaaaaccgt
     2281 gatttttcca gaacctgtat atttggaagg tgaacagcaa gatatcgcag ttgaagtctc
     2341 tatgcaatat acagacggct accattccaa tatcatgagt tttgccaaca atatccatac
     2401 gtatgaaggt ggaacacatg aatcaggatt caagactgct ttaactcgtg tgataaatga
     2461 ttatgcccga aaacaaaagc tgatgaaaga aaatgacgac aacttgaccg gtgaagacgt
     2521 gcgagaagga ttgacagctg ttatttctat caagcatcct gaccctcaat tcgaaggaca
     2581 aacaaaaaca aaattgggca attccgaagt acggacagtc actgatcggt tatttagcga
     2641 acatttcatg aaattcttgc tggaaaaccc aagtgtgggc cggcaaattg ttgaaaaagg
     2701 attactagct tccagagctc gtctagcagc gaaacgtgcg cgtgaagtaa cgagacgtaa
     2761 aggtgcttta gagattagta atctgccagg aaaattagcg gactgctcta gcaacgatcc
     2821 tgaaaaatgc gaattgttca tcgtcgaagg agattcggcc ggcggatcag ctaagcaagg
     2881 tcgtaatcga gagtttcaag ccatcttgcc tattcgtggg aaaatcttga atgttgaaaa
     2941 agcaagcatg gacaagatct tggcaaatga agagatccgg tctttattta ctgctatggg
     3001 tacagggttt ggagaagatt ttgatgtatc gaaagctcgc taccacaaat tagttatcat
     3061 gactgatgcc gatgtcgacg gcgcgcatat ccgtacattg ctgctgactc ttttttatcg
     3121 ttacatgcgt cctattgttg aagctggata cgtctatatt gctcagccac ctttatacgg
     3181 ggtaaaacaa gggaagaata ttacgtatgt acaaccagga aaaaatgcag aagaagagtt
     3241 gaaacaagtc gttgcttcac ttcctgcctc accaaaacca agcgttcagc gttataaagg
     3301 acttggagaa atggatgatc atcaactatg ggaaacaact atggacccaa gcaatcggat
     3361 gatggcccgc gtcagtgtgg acgatgctat tgcagcagat cagatatttg aaatgttgat
     3421 gggggatcga gtagaacccc gtcgtgcatt catcgaggaa aatgcacact atgtgaagaa
     3481 cttagatatt taatcatgaa ggaggaaaaa gaatgagtga agaaatcaga gaaaacatcc
     3541 atgatgtcaa tctaaccagc gaaatgaaag actccttcat cgattatgcg atgagtgtta
     3601 ttgtcgcacg tgcacttcct gatgtcagag atggtctgaa acccgttcat cgccgtattt
     3661 tatacggcat gaacgaatta ggtgtaacac cggataaagc ccataaaaaa tctgccagaa
     3721 tcgtcggaga tgtcatgggt aaataccatc ctcatggaga cattgcgatc tatgagtcaa
     3781 tggtacggat ggcacagcca ttcagctacc gttatatgct agtggatggt catggaaact
     3841 ttggttctgt tgacggtgac ggtgccgccg ctatgcgtta taccgaagca cggatgagca
     3901 aaatcgctac agaaatgctg cgtgatatca ataagaacac tgttgatttc caaagcaact
     3961 atgatgatac agaaaaagaa ccagttgtac tacctgctcg cttcccgaat cttttagtga
     4021 acggaacaac ggggatcgcc gtaggtatgg ccacgaatat cccacctcat aacttgtctg
     4081 aggtagtagc ggctatcgat ttgctgatgg ataatcctga tgtgacgacc aatgaattga
     4141 tggaagtatt acctggacca gattttccaa caggtggttt ggttatgggg aaatcaggaa
     4201 tccgaagagc gtatgaaaca ggtaagggtt ctattaccgt acgtgcaaaa gttgagatta
     4261 ctgagatgcc aaatggtaaa gaacggatca tcgtgacaga attgccttat atggtcaata
     4321 aagcaaaatt gatcgaacgg atttctgaac tgcacagaga caagcgtatc gaagggatca
     4381 cagatttgcg ggacgaatct tcccgtgaag gtatgcggat cgtcattgac atccgtcgtg
     4441 acgccagcgc atccgttatc ttgaataact tatataaatt gacatccttg caaaattcat
     4501 ttggattcaa tatgttggcg atcgaaaaag gtgtgccgaa agttttgagc ttgaaacaaa
     4561 tccttgaaaa ctatatcgaa catcaacgcg aagtcatcac acgacggacg gtctttgaaa
     4621 aagaaaaagc agaagcaaga gcacacatct tagaaggttt gcgtattgct ttggatcata
     4681 tcgatgaaat cattgcgatt atccgcgggt ctaaatcaga tgacgaggca aaagcaacaa
     4741 tgatcgaacg gttcgattta tccgatcgcc agtctcaagc tattttagat atgcgtttac
     4801 gccgattgac cggtttggaa cgggaaaaaa tcgaaaatga ataccaagaa ctcttaaaac
     4861 tgattgaaga tttaactgac attctggcaa gaccagaacg tgttacagaa atcatcaaga
     4921 atgaattagc agacttgaat caacgatttg gtgataaacg acgcacagaa ttactagtcg
     4981 gtgaggtctt aagtctggaa gatgaagatt taatcgaaga agaagaaatc gttattacat
     5041 tgacaaacaa tggttacatc aaacgtttgg caaataatga attcagagct caacgaaggg
     5101 gtggacgtgg tgtccaagga atgggtatcc acaatgacga cttcgtcaaa aatctggttt
     5161 cttgttctac ccatgataca ttgttattct ttacgaataa cggaaaagtg tatcgggcaa
     5221 aaggatacga aattccagaa tacgggcgta cagccaaagg aatcccaatc atcaatttac
     5281 taggtatcga ttcgagtgaa agcatccagg caatcattgc ggtgacggga gaagcagaag
     5341 aaggccacta tctcttcttt acgacgcgtc aaggtacagt aaaacgtact tctgtcactg
     5401 cttttgctaa catccgaagt aatggtctga tcgcaattgg tttgaaagaa gacgatgagc
     5461 tcgtcaatgt gctactgaca gatggtcaat ctaatatcat tattggaaca cataacggct
     5521 actctgtcac tttcaaagaa gaagcagtcc gcgatatggg acgtacagct tccggggtca
     5581 gagggatacg cctgcgtgag gaagattatg tcgttggggc agccttaatg aaggaaaatc
     5641 aagaagtatt agtgatcaca gaaaaaggtt acggaaaacg gacaaaagta tcggaatatc
     5701 cagtgaaagg ccgcggaggt aaagggatca aaacggcgaa catcactgaa aaaaatggtc
     5761 cactagctgg attgaccact gtttctggag atgaagacat catgctgatt acagataaag
     5821 gtgtcattat ccgtttcaac gtatcgactg tttctcaaac tggacgttca acattaggcg
     5881 tacgtttgat gaagatggaa gctgatacga aagttgtcac gatggcagca gtcgaaccag
     5941 aagctgcaga acaaacagtt gaagaacaag gatcagaaga ataaccatca agactaagtg
     6001 tgtaagctag caagaataac cgattaaaaa atctggttat tcctgctggc ttttttgatt
     6061 agttgaattt ctcttaaaat attcgaaact gttcattctg tattgctttt gaccaaaata
     6121 gagtgtataa ttagagcttg tgagtagtct aattaattag ataactctcc ttgctcttag
     6181 gaacctaaga gccgaaagtc cacagggagg tgaatatcaa tggaaaacac gaaatatgaa
     6241 atcatgtaca ttattcgtcc aaacattgat gaagaagcaa aaactgcttt aatcgaacgt
     6301 ttcgatgcaa tcttgaaaga taacggagca gaagttatcg aatcaaaaga ttgggaaaaa
     6361 cgccgtttcg cttatgaaat gaacggttac cgtgaaggta tctatcacat cgttaaagta
     6421 tcttctccat catcagcaaa tgctgtcaat gaatttgacc gtcttgctaa aatcaacgac
     6481 gatatcattc gtcacatgat tgttaaagaa gaagcttaat tgttgtttca tgtgaaacaa
     6541 tagaaaacga tgagaggaga tgactatttt gattaataat gttgtattag ttggacgtct
     6601 gacgaaagat ccagatttgc gttacacagc aagtggtacg gcagtcgcaa catttacttt
     6661 ggctgtgaat cgtaatttta caaaccaaag cggcaatcgc gaggctgatt ttatcaactg
     6721 tgtgatttgg cgcaaatcag cagaaacttt agcaaactat gctcgtaaag gaacactttt
     6781 aggtgttact ggacgtatcc aaactcgttc ttatgataat cagcaaggac aacgtgtata
     6841 cgtgacagaa gtagtagctg acaacttcca attgctggaa agtcgttctg catctgaaaa
     6901 tcgccaacaa agcggcggat tccaaagttc tggtcaatca gctggcggat ttggcggaaa
     6961 caataactct aatcaaacat ctcaatcatc caacggtatg cctgatttcg accgtgatac
     7021 ttctgaccca ttcggctcaa gttcaacgat cgacatttca gacgatgatt taccattcta
     7081 aacgaatttg ataggaggga aatagaatgg cacaacaaag aagaggcgga cgtaaacgtc
     7141 gtaaagtaga ctacattgct gctaaccata ttgaatatat cgattataaa gatatcgaat
     7201 tactaaaaag atttatttca gaacgcggta aaatcttgcc acgtcgtgta actggtacag
     7261 gcgctaaaaa ccaacgtaaa attactgttg caatcaaacg cgctcgtatc atgggcttgc
     7321 tacctttcgt tagcgaagac taataaatcc taggaattga atgactgatc cttttgatca
     7381 gctattcaat tccttttttt ctgtaaaaat aacctctatt cgtttagtcg ctcgaatgac
     7441 gaaagttatg gtaaaatcaa attagtcata tatgggagga aaattatgga aaataaaaac
     7501 aatcatttat ccccgaaacc tctcttcctt atcctgttta tattaatcga agtattggta
     7561 gtcttaattt taccatttcg ttttgttagc gcttcggtca ttctattgat gaatttatgg
     7621 ggtgttcgct attggttgaa aatgaaacgt tggcttattt taaataaacg tgaaaaaatc
     7681 cagcaggctt cgactgtagc tgaaaccaat ctagcttatg tctcagaagt catgcctgta
     7741 ggagtgattg cttatcagcc atcaagccaa aaaatcgaat ggctcaatcc attagcattg
     7801 aaaatcaaag atcaaagtgg attaacagag gaagaattgc tagatacttt ttttactgca
     7861 aaagaaaaaa agaaaaacca agtctatcta gcagataaaa catttcagtt tgatatggat
     7921 acagtaaagg gtgttgttta ttttaatgat attacccaaa accagttgtt aaaactccat
     7981 cagacgaaca gtcagccggt gattggtatt ttatctattg ataactatgc agatgccatt
     8041 gataaattag atgacaaaga gatttcttat ttgaactctt tcgtcactac actagtttct
     8101 gactggatga atgaatacca tgtctttttc aaaagaatca acgcagaacg gtttttcttc
     8161 gtagcacaga tgatcgatct gaaaaagatg atggataaaa aatttgattt gctggatcgc
     8221 tttcgagcag aagctgaaaa acagagctcg cctatcaccc ttagtatggg gattgcttat
     8281 ggctcaagaa ccctcgatga aatcggtgga gaagctcaga ataatttaga tgttgcttta
     8341 gtccgtggag gcgaccaagt tgtcgtgaaa gaggtaaaag aaggagcaaa acctgtttat
     8401 tatgggggga aatctgctaa gaatgtcaaa cgcacgcgtg ttcgttctcg agcgatgagt
     8461 accgctttgc gtcggatttt tgatgaaaca ggcgatgtgt ttatcatggg gcacaagttt
     8521 ccggatatgg atgctttagg ctctgctttt ggtgtcagtt gtctggcacg cttcaaccag
     8581 aaaaaagctt acatcgttat caatgagaac gagatcattc cagatgtaga acggtgtctt
     8641 gaagaaatcc ataagcatcc tgaattagaa atgcaactaa tctctccaga acgtgccata
     8701 gagctgaaaa aagaagagga cctcctcgtg atggtggatt accataaacc ttctctatcg
     8761 atctctcagg gcctatatga gcaatttgat aagattgtga tcattgatca ccatcgtcgt
     8821 ggggaagagt ttccaagtaa acctctgctg acttatattg aatcttcagc ttcttcagct
     8881 tcagagctag tttctgagct gatccaatac caaagcagca aaacaaatcg cttagatcgt
     8941 tttgaggcca cattattgct tgcagggatg gttgtagata caaatagttt caatgtccgt
     9001 acaactgcac gaacttttga cgttgccagc tatttaaggt cttgtggagc agacgcatcc
     9061 ttagtacaat atttattgag ctcggattta gcgacatact tggagatcag caatttgatt
     9121 gctggaagcg actatgtgac ttctgatatt gttgtggcgg cagggacaga cgaaaaagag
     9181 tataatagtg ttatagcagc aaaaacagca gatacattgc tttcgatgat caatatcaat
     9241 gcagctttcg tcattacaaa gcggacagac ggcttgattg ggatcagtgc cagaagtacc
     9301 ggcacgatca acgtccaaat catcatggaa tccttaggtg gcggaggaca cttcacaaac
     9361 gcagctactc aactggaaaa tacgacagtt gaggaaacaa aacagaagct atttgctgca
     9421 atcaaagaaa atatgaatca aatatatgat aaggagtaat ccaaatgaaa gtaatttttt
     9481 tacaagatgt aaaaggaaaa ggtaaaaaag gggacatcaa agaagttcca gcaggttatg
     9541 cacaaaatta tctaatcaaa aataacttgg caaaagaagc aacgaaaagc agtatcagtc
     9601 agttagcagg acaaaagaaa gcacaagaaa aacacgaagc tgaaatcttg gaagaagcta
     9661 aaaagttaaa agaattcttg gaaaaagaag atactgtagt cgaattgaag gcgaaagcag
     9721 gggaagacag ccgtttgttt ggttcgatcc cttcaaaaca aattgctgaa gggttaaaca
     9781 aacaatacaa aatcaaatta gataaacgaa aaatcgaatt agaaaatccg atccgttcac
     9841 taggctacac aaacgtacct gttaagcttc atcatgaggt gacggctacg atcaaagttc
     9901 atgtcgtaca agaataacaa atcttgatag cgatgttcag ctggtaagta taaccagaag
     9961 gaaaaaagac aaaccgaaat ttatctgaga aaacagctgc agcaatgaaa gcaaaagctg
    10021 caaatcgatt tcagattgat ttcggtttct tttttgggaa cagcaaaata gcataaagaa
    10081 aacgagtata ataaaagaga actatttttt tattacactt tcggtacgaa tgatgacttt
    10141 tctctcattt tcttgtaaaa tgaagcaatt gaagacaagg agcgatacgt atgaatgaag
    10201 tgtggcagga tcgaatccca ccgcaaaata ttgaagctga acaagcggtt ttaggctctg
    10261 tttttcttga cgcagaaacg atcattgatg ccatggagta catagagcca aaagactttt
    10321 atcgtcgtgg ccatcaaatt atttttgaga caatgatcga gttaaatgat cgtaatgaag
    10381 cgattgacgt ggttactgtc aaagaccggc tggaacaagc caatttgtta gaagatgccg
    10441 gtggtttaag ttatctctca gacttggcat tagcagttcc gacagcagca aatatcgtct
    10501 actatgcgaa aatcgttgaa gaaaaatcat tgctgcgtac attgatccag acagcaacag
    10561 gaatcgttac gaaaggattc gagcaaggag aagaagttca aacaatttta gatgatgccg
    10621 aacgcagtat cttggaggtt tcggaaaaaa gaaatcgaag cggcttttta tctattgctg
    10681 aagtactgaa ctccacgatt gaaaatatcg atcgactagc tcaaaacaat gaagaaatca
    10741 caggtctacc aactggctat caaggtctgg ataaaatgac agcaggtttc cagcccgaag
    10801 aactaatcat tcttgctgca cgtccagcgg taggtaaaac agcgtttgca ttgaatattg
    10861 ctcaaaatgt aggaacaaaa acagatcgtt ctgttgcgat atttagtttg gaaatggggg
    10921 cagaatctct tgtaaatcgg atgctttgtg cagaaggttc gattgaggcc agccatttac
    10981 gtacaggtca gctttcggaa gaagaatggt cgaatctgat cgttgcgatg gggagtcttt
    11041 ctcgagcaaa tatttttatc gatgatacac cagggatcaa aatctctgaa atccgtgcga
    11101 aatgtcggaa actagcgcaa gaaaaaggca atctaggctt gatattgatc gattatttgc
    11161 agttgattga aggtaacggt aaagagaacc gtcaacaaga agtatcagat atctctcgcc
    11221 aactgaaaaa actggcgaaa gagctgaaag tacctgtcat tgctctttca cagttatctc
    11281 gtggagtaga acagcgacaa gacaaacgac cagtgctaag tgatattcgt gaatccggat
    11341 caattgaaca agatgcggac atcgtagcct tcttgtatcg agatgattat tatgaaagag
    11401 aaggcggaga tgacgatgat ggaaacgagc caaaaaatga caacgtcatc gaagtcatca
    11461 tcgagaagaa ccgaagcggt gcacgaggaa cagttgaact actgtttatc aaagaataca
    11521 ataagttttc gtcgctttcg ccaagagaag aattttaaag aagaggttgt gagccttgag
    11581 caatcccgag agctctcgta agaagatgca aggagtaacc gcaggaacga ctagagtact
    11641 taatttaaac agatctccaa agggattgtg acaaaagtct tgtcacagtc cctttttccg
    11701 aataaacggt gttcaatcag ctgacccttg gtattagctc agcaaacgtc aaaatatgag
    11761 gaactatttt gacgtttgtt tctctaatac tcaggtcaaa acgctgatct tacgacctct
    11821 tttccttaaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata tcatcaaaca
    11881 tgagaagcag ttttttgaaa ttgctccttg tgactcagag ttaaacggca ggctcacaac
    11941 ctctttctta aacggtgttc aaaagcttgc atctgcggta atacgcccaa tcaaacgaaa
    12001 aatatgagaa gctatttttg tttggctgtt cttattactt gatgcaggac agctttttca
    12061 caacctctga ttcacggtgt tccaaaagta gcttcttcga aaaataagtc gaaatttcac
    12121 aaaaatttga gaagcaattt tcgtacattc cttcttattt cttgaagctg accacttctg
    12181 ttacaacctc ttttttaata accattctaa aaagataaag ttcgtttttt aagcgttttt
    12241 ataaaataaa aataaaaatc attcgatttt atttgaaata tgtatctatt attgatacaa
    12301 tggttcagga ttaaataata tagaacgagg tgttcacatg tcatctgtag tagtagtagg
    12361 tacgcaatgg ggcgatgaag ggaaaggaaa aatcacagac tttctcagtg aaaatgctga
    12421 agtgattgca cggtaccaag gtggcgacaa tgcagggcac acaattaagt ttaacggtgt
    12481 gacttataaa ctgcatttga ttccttctgg gattttttat aaagacaaga tcagtgtgat
    12541 cggaaacggc gttgtagtca atcctaaatc attggttaaa gaattagctt atttacatga
    12601 aaaaggtgta gaaacaagta atttgcgtat ttctgaccgc gcgcacgtaa tcttgcctta
    12661 tcatatcaaa ttggaccaat tacaagaaga tgctaagggc gaaaataaga ttggtacaac
    12721 gattaaagga atcggacctg cctatatgga taaagcagct cgtgtaggta tccgtattgc
    12781 agacttatta gataaagaaa tttttgaaga acgtcttcgt ttgaatctag atgacaaaaa
    12841 ccgtcaattt gtaaaaatgt ttgattcaga accacttgat tttgacgata tttttgaaga
    12901 atattatgaa tacggacaac aaatcaaaca atacgtcaca gatacttccg ttatcttgaa
    12961 tgatgctttg gatgcaggca aacgcgtgtt gtttgaaggc gcacaaggtg taatgctgga
    13021 tatcgaccag ggaacttatc cttttgttac ttcttctaac ccagtagccg gtggggtaac
    13081 aatcggaagc ggtgtagggc cttcaaaaat caataaagtt gtcggcgtct gcaaagccta
    13141 tacgtcacgt gtcggtgatg gaccatttcc aactgaatta tttgatgaaa caggagaaca
    13201 aatccgcgaa gtaggacgag aatacggtac gacaactggt cgtccgcgtc gtgtaggctg
    13261 gtttgattct gtagttatgc gccattctaa acgagtttca ggtattacca acctatcttt
    13321 aaactcgatc gatgtattaa gtggattgga aacagtaaaa atttgtacgg cttatgaatt
    13381 agatggcgaa ctaatctacc actatccagc aagcttgaaa gagttgaacc gctgcaaacc
    13441 aatctatgaa gaattgccag gctggtcaga agacattaca ggatgcaaaa cacttgcaga
    13501 actgccagaa aacgcacgta actatgtacg tcgtatctca gagcttgttg gtgtacgtat
    13561 ctcaacattt tctgtcggac ctgatagaac acaaacaaac atcttagaaa gcgtctgggc
    13621 gcaaatctaa ggataaaaac gacgactgaa tcaggacgtt cttaccagag cgagtcgaag
    13681 tgtttatcta tacgataata ataacttgaa gaggtagtga aagagacgtt tagccttatt
    13741 gccgataggc tgtctcttga acactgttta ttcagaataa gggactgtga caaaaaccgt
    13801 gtcacagtcc ctttttccga a
//
LOCUS       DADQCX010000074        13720 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.074, whole genome shotgun sequence.
ACCESSION   DADQCX010000074 DADQCX010000000
VERSION     DADQCX010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.074"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            54..506
                     /locus_tag="J8R83_002044"
     CDS             54..506
                     /locus_tag="J8R83_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575169.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            520..1209
                     /locus_tag="J8R83_002045"
     CDS             520..1209
                     /locus_tag="J8R83_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575170.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1334..3685
                     /locus_tag="J8R83_002046"
     CDS             1334..3685
                     /locus_tag="J8R83_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAZ9575171.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3765..4160
                     /locus_tag="J8R83_002047"
     CDS             3765..4160
                     /locus_tag="J8R83_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575172.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4485..5102
                     /locus_tag="J8R83_002048"
     CDS             4485..5102
                     /locus_tag="J8R83_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575173.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5143..5442
                     /locus_tag="J8R83_002049"
     CDS             5143..5442
                     /locus_tag="J8R83_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575174.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5476..5643
                     /locus_tag="J8R83_002050"
     CDS             5476..5643
                     /locus_tag="J8R83_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9575175.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5688..6293)
                     /locus_tag="J8R83_002051"
     CDS             complement(5688..6293)
                     /locus_tag="J8R83_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575176.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            6418..9405
                     /locus_tag="J8R83_002052"
     CDS             6418..9405
                     /locus_tag="J8R83_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAZ9575177.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            9554..9763
                     /locus_tag="J8R83_002053"
                     /pseudo
     CDS             9554..9763
                     /locus_tag="J8R83_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9898..10074
                     /locus_tag="J8R83_002054"
                     /pseudo
     CDS             9898..10074
                     /locus_tag="J8R83_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            10056..10412
                     /locus_tag="J8R83_002055"
     CDS             10056..10412
                     /locus_tag="J8R83_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009009558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575178.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
     gene            complement(10926..11093)
                     /locus_tag="J8R83_002056"
     CDS             complement(10926..11093)
                     /locus_tag="J8R83_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9575179.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(11181..13121)
                     /gene="tet(S)"
                     /locus_tag="J8R83_002057"
     CDS             complement(11181..13121)
                     /gene="tet(S)"
                     /locus_tag="J8R83_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HAZ9575180.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            complement(13122..13208)
                     /locus_tag="J8R83_002058"
                     /pseudo
     CDS             complement(13122..13208)
                     /locus_tag="J8R83_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance protein"
BASE COUNT         4618 a         2122 c         2496 g         4484 t
ORIGIN      
        1 tatcttatcg tagatatata ttataaattt aataagaaag cgaggtgaga atcgtgaaaa
       61 aaacgatact aagtattttt tcagtattta caatattaat tgggggctat tttcttttga
      121 atttagattc tgttaattca aacgctcaaa taaaagatca aagagtagct gaacataata
      181 ataaaaaaat gagtttgacc aaaaatatct attctatgtc agatgaagaa ttgtataaag
      241 aatttggtga tttatccggg gaacagttag aagaaagtat tccaggaatt agtgactcag
      301 ataaaattgt tgtcttgtct gctggtgggc aattaatggg agatggcaaa tccgaattag
      361 ttagttataa acaaaatcac agacagttta ttgatgttaa tactgattcc aacgctattt
      421 cgattaagga tctaaaagag cttttaaata gtaaaagaaa tgaattaaag cagataaaag
      481 aaactaattc agtggaatta gagtaaagga agattcatta tgaaaaagat ttttggtgtt
      541 tctgttgggc tacttatgat gttaacattt ggaaatgcag tatatgctgc tgagaaagaa
      601 gttatttcag atccagagca gtacgcctca cgatactttg ctgattttga agaagaagat
      661 aaagtacttg cattgccaga aggtggtttt ttaaaagggg aagctaaaat tgtatctatg
      721 gataatccag atataattca aggttcatat aattcagaaa ctgatcctgc ttcagtttca
      781 gtgacagaag caaaaaaaat tgttgctgaa aaattcaaaa atgatattga aactactcca
      841 attatgcctc gaggagcatt tccacccgat gttggtacta gcggacacct tcttgtacta
      901 gcaggaggag gaagctataa atcacagcca tttagtggtg cgggatggcg ttttggaggt
      961 atgggtgtaa aaccagctga tggtacaggc aactttttac gttggaaatc ctacattgac
     1021 gatggaagag taggaaatgt aaatcaagcc aacgcaacta aatctggttc tattcaagga
     1081 atggcattgt atgctcgtga aggattcaaa tactttgcac caaacgggcc tggttggaca
     1141 atgaatatag gtatttatta cacttataat cctgttgcag gtacgtatta tgttgttcaa
     1201 aatatttaat aaaacagcac aaagagattt ctttgtgctg ttttattatt tttagttgtt
     1261 gacaaacact aaaatataaa atataatcaa cacataaacg aacgtatgtt cggcaagaaa
     1321 gcaggggatt tttatggatg agatggtttt aagtactcag aaatggctaa acaagaaata
     1381 cagtaatgtt acagggtttg ataaggttcc agaaaatggg cgaacagggt ggcctacaat
     1441 ctatggactt attgaaggac tacaagtaga acttggtatt actaatctag tagctaattt
     1501 tggacctacc actgaaaaaa tgtacgataa tcaggttact cctaaatggg gcaaaaatct
     1561 acctaaaaat attgtatttc ttattcaagg tgccttttgg tgtaagggga ttaatccagg
     1621 tggcttcgat ggggtatata ctccatattt agatactgct gtaaaagagt tgcagactga
     1681 tgcagggttt aatggaagcg ctgtaactgg agttttggat gcgaaatggg ccaaagcgtt
     1741 atttgatatg agtgcttttg ttcttgttcc cggcggagat agtaaaatta gaaaaatgca
     1801 gcaatggtta aatgtaaatt atttagaata cacgggaata atgccttgtg atggtattta
     1861 tcaaagaaat tcaaatcaag cattaatttt tgcattacaa gctgaactag gatattctcc
     1921 cagtgaagca acagggtctt atggtaatgg gacaactagt aaaacttatc ctgtgtctga
     1981 aggtaactcg ggaaactatg taagaataat tcaatatgga ttatatgtta atggttattt
     2041 tgaagacggt acattcgatg gtattttcac taaatatatg ggtttagaag tactggcatt
     2101 ccgaaaattt atggtattgc ctgaatatac tgaaatagca gatgttgttg taataaaagg
     2161 actattgtct agcgctggag atattagaag atctgcagat ggcgcagata cttctacgca
     2221 attaactaga tctcaaatcc aaacattggt tgataatgat ataaaaatag ttggtagata
     2281 tcttactggt actgttggaa ttggaaaaga tgaacgaaat aagtatctaa ctacagagga
     2341 attgaataat attttttcta aaaatttatc tgtgtttcct atctatcaag atggaggtgc
     2401 agcattagct tattttactt atgatcgtgg cttatcagat ggtaagaagg ctatagatgc
     2461 agcaaaaaat ctaaatatac cattaacaac agttatttat tttgctgttg atctagacat
     2521 gttaggggaa gaaattcttg catatgctgg agaatatttt aagggggtat ctgctgtaat
     2581 gtcatatagc gggtatcaaa cgggtgttta cggaacaaga aatgtttgtt ctcaaataat
     2641 caataacggg tatgcttcgt ttgcatttgt ttcagatatg tcgactggtt atagtgggaa
     2701 tttaggtttt cctatgccta gacaatggtc ttttgatcaa tttgttgaat ttaccatagg
     2761 aagtggcaac ggagctgttg gtatcgattt aatcgctaca tcgggtagag atagcggatt
     2821 taatgagtta tcaaatgata ctaataatga taattacatt gccaaataca atcagaaggt
     2881 tataaatcag atggtacgtg cgtatcaata tctatcacaa gctggtcttg ataatccttg
     2941 gaaccctcat ttgacatttt atagatatgt aaattattct ggtttgtcat gggacatcat
     3001 ttcttctcct gtaacagagc atgatagaaa aatttatgat gaatatagga ataaattaac
     3061 taatagcgag ggcctgtata attattttat agatcctaat actggttcaa taataggttt
     3121 gcctcactta attgtgacgt tacaatcaca gatgtttcta gccgacacaa tcaatgatag
     3181 tgtttctgac tttgcaggtt ggttaggaga tttaatgact tgctggggtg aagttaagaa
     3241 attaggaata caaatggagc aaggtgtatt tgcattagta ggtacggctg caggtggaac
     3301 atttagtcta gaagatttat accaagatgt tgacgcggta aatgtttata ccttagcaaa
     3361 aagaaattct gattcaacag ctttatcggc tttaaaaacg tactattgtg ataagggtgc
     3421 tattgataga tttaatcaat ttgttaagaa cagatttggt tcttcagata aaatcgcttc
     3481 agtaacaaat agtttattag aaaatgacga aacagttgat atcttaggtg tagggataat
     3541 ttcatttttc attgataaaa tagttaataa ttcacttggg acagatttta cttatcttga
     3601 ttttattgga gatgagggga aagttgcaaa tggattttct gaaaaaatta ttcaatttca
     3661 agaaaataga agtaaactta attaagaatc gtttactatt taaacagtgt ccttttcctt
     3721 tttaaatata tacgataaaa taagtatatg aattgtaaaa ggacatgatg attatggaag
     3781 aaatagaatg gaataatctg actcaaaata ataaaaataa ttctggatgt ggaattatct
     3841 ttatgtttgt tatagttttg ggaatagtag tacttttaat aactgtcaag atagtagatt
     3901 actttgcgaa tactcctgaa gaacaaatac agagaaaact tcctgagttt gaaagagtac
     3961 caccttatga tccaagagat aattcatttc aagtaaaaaa attaaaagag tctccaaatg
     4021 aaatgtggtt tgaagttaca gttgaatcaa gcgacttcaa agaaaaaaag aaagaataca
     4081 attatattgt aaaggcaaaa gtatcaaaaa gatttatttt taaccctaaa ttagaaatat
     4141 atagtgttgt aatagaataa tagtgttaaa aaaattgtaa aagttaaaga agtcaaattc
     4201 tgatgtgaaa aataaaatat accatggaag acataaaaga aaaactggat aactagttta
     4261 tttaatggca gaccgttaag gcctgccatt tttatgtatt ttagcggaat aaatataatc
     4321 atgcgggagt gtaaacttac tgtttcaaaa agtatacttt ttgacatgcc ttgattttct
     4381 ttgtttatgt atggcataat aaccacataa tacaatttga aacgtttctg atttaatctg
     4441 attgttttga aacaatttta gtgaaaaaag ggtagataaa aacgatgaga aaattttttt
     4501 atatccgggt cagtagttat gatcaatcga tcgaacgaca actgatttcc gcgaaggaat
     4561 taggaatccc tgaagaatat atatttgtag aaaaagccag cggcaaagat tttaaacgcc
     4621 ctgaatatca attaatgaaa cggatgtttc gaaaaggaga tttactctat ctacaatcat
     4681 tagatagact aggcagaaat aaacaaatga ttttagaaga atggcgagaa ttaactaagg
     4741 aaaagcagat tgatatttct gtgttagaca tgcctctgtt agatactgct agttacaagc
     4801 aactagatgg gttagagacg cttatctctg acttaattct gcaattactc agctatatgg
     4861 ccgaagacga gcggaaacga attaatagcc ggcaaagaga aggcgtagaa gctgcgaaac
     4921 aaaagggtgt aaaattcggc agaaagaaaa ttgctttacc tcctgaattt cctgcgatct
     4981 attctgactg gaaagcagga aagataactg cagtctatgc tatggatcaa ttgggcatga
     5041 aacgaaatac cttttatcga cgggtgaaag aatatgaaca taccttgcac cacttttctt
     5101 gatagatata acagctatta gacgggaagg gagagtttga aaatggactt aacgaatcaa
     5161 agggtcgttt ttactggaac gctgcagcaa atgacacgaa cccaagccat cggtttggtt
     5221 cactctttaa acggccattg tcaatcaagt gttacttcaa aaacaaattt cctggtttgt
     5281 ggtcagtatt ctaagtcgtt gtttgatgat tctctctata caaaaaagga acaaaccgcg
     5341 cgggacttga ttgcgttagg tcatgagatt accattttat cagaagtcga attttatgcg
     5401 ttaattagtc aacagttgaa agaatggcaa cggtatttat aatcgttagt aaaatttaca
     5461 aggaggaaaa tttttatgaa gcgaaaatct tatgatcgtt ggggcattga aataactagt
     5521 tttaatcgaa atattgcttt tcacgtggag tgtgactgtg gggaattagc aaaaagtgtt
     5581 tatcaaaaaa attactttta ctgtcctaaa tgccatcgcc gatacggggt acatggaaca
     5641 tagaaacgaa atagtgcggt agaaaagcga atgaatgtag tatatttcta caaatcattc
     5701 gctttcttta ttttataaat agttggtcga gagatcccgt tttcttttgc aatctctgca
     5761 actggaatgc cttgctttaa catgtccacc acggttttaa aaactaagcg tttttgcgga
     5821 tctgttgagt taatagaata ctcgattggt cgtcccttat atcggccggc tttttgagcc
     5881 aataatactc cttgccgctg acgttcacga attttctcac gctcgttttg tgcaatataa
     5941 cttagcagtg ataaaaacat atcgaacata gcggtatcca ggagttcatt tccagtatta
     6001 aaatctaaaa actgtgcatc taatattttt aacgctactt ttttctgttt cataaaagca
     6061 actgtatttt ttatatcttc ataatctctt cctaaacgat ctagtgatgt aacgatgacg
     6121 caatcacctt cacggatata atttagtaat ttttgaaact caggacgctc agtatcttta
     6181 ccactggctt tttcttggaa taatttatca atgttaagtc cttccatcat tgccaattgt
     6241 cgatccaaat tttgatcttg tgaagatact cgaatatagc caatttttcc cataaaaaac
     6301 tcctttttaa aagtgatata atttacatgt aaaatttact tgtagtttta ctgctatcat
     6361 agcattttta aaaataaatt ttatgtagac ttaaaattta cttcatggag ggtttaaatg
     6421 gatgaaatca aaagtaacaa aaaagcattt ggcatttatt taggagaacc tagtacagaa
     6481 caattaaacc aattttttta tttgcatgaa aaagatttag aattgatgga gactatacga
     6541 cgaccagcta ctagattagg ttttgcacta cagttagtct cactacgttt tttaggaact
     6601 tttatattag atcttaccaa tattccccaa aatgtattga gttatgtagc aactcaacta
     6661 aatattgatc ctggagaaat tatctactat agcaggagac agaccaggta tcagcacaca
     6721 aaattgataa aatcacatta tggatatcaa gatttcaacc aaccggaaat agaaacatac
     6781 ctagctaact ggcttttaaa tagagcgctg tatacaacag aatcttcaga tatgttgttt
     6841 gatatgcttc taaaaaaatg tctggatgaa aagattgttt tacctggaat tactactttt
     6901 tctcgttttg ttgctagtgc aattgaaaaa gctgaagagc atttataccg acaattgtct
     6961 ttggttccaa ctgaagatga gagaaagcgg cttctcaatc atttagaatt aattggaact
     7021 ccagtttatg gggcaataat caaaatggac attttgagaa ccccgttagc tgacgatagt
     7081 cataaagaaa tagccagagg ttttgaccga ctaaagcaat ttcaagcttt ctctactgaa
     7141 aaatggaaga tggaatctat tcctgaaggg aaaataaaag ttcttgcaaa ttatgcattt
     7201 aaagctaaag ctcaattaat tcaacgaatg agtgaacaga aaaaactggc gttgttagtg
     7261 gcatttattt tcatatacaa acgtaaggct atggatgaac aaattttagc actatctaat
     7321 ttttttgaaa ctgtttttag acgcgccaaa aataaggaat ctaaagaacg tcttcgtacc
     7381 ataaaagatc tagatcgagc cgcatcgaca ctttcagata ttgtagattt agtaatgtcc
     7441 agtcattctg atactaatga actatccctt cgcgatcgta tcttagaaaa atattctgag
     7501 gaaaatgtta ccgaagctgt atcgcaagtt cggctattgg ttaaaaatga tcgtgaacca
     7561 atagccattt ctgaacttct gaacacttat cgaaagttca gaaaatttat tccggatatt
     7621 ttaactacac taacatttga cagcaatgac tacggtaaca actgtaagga actctggacc
     7681 ttcattaata atagatttcc taagccgatt acttacaaaa tgtttggagc tattaaacat
     7741 actcttccaa agaaatggat ttattacatt catgaatacc ctgaacaaac taataaatgt
     7801 gtattgattg cagctgtcga attgttaatt caatctttaa aacgccatga tatttatatt
     7861 cctcagagtg tcttatataa caatcctatg gattgcttga ttgatgagaa aacttgggtt
     7921 caacaaaaat acgttttatt agaacaacta gatcttcctt cttcagcaaa tgaaatgtct
     7981 ttatggttaa agaacgattt ggaactgtct tataaagaag cgctaaatcg ttggcctact
     8041 tctaaaatgg ccagaataga aaatgcagat cgcctggttg tctctagact taaaaagaca
     8101 tatgaaaaaa aggaagataa gtcttttaga cgtcgcattc agcagttact tcctaaaatt
     8161 gatttgtcag atttgttatt ggaagtaaac caacagttaa atcttactca atcatttaac
     8221 cacttaagtg acaaggacac caaaatgaaa gacttggata ttagtttatt agcagttctt
     8281 ttatcagagt cctgcaatat tggtttttcc ccggtttcaa aagaaggatt tgattcttta
     8341 aagtatgatc gtcttgtcta tgtcaatcat cattatattc gagtggatac actttcagga
     8401 gctaatcaaa aaataataca tgcacacagg aaacttgcca cctctaagat atggggtgat
     8461 gggcatatgg cttcagctga cggtattcgt tatatcacac cacaacgttc cctatattct
     8521 agaagtaatc caaaatattt tggccgtggt cgtgggatca cattctacaa ttttgtctct
     8581 gatcaatata tagggttcca cggaatggtc gtttcaggga cactgcgaga ttcgctttac
     8641 cttctagaag gattcctcaa tcaacccagc gaattaactc ctaatcagat catgactgat
     8701 acagctggtt atagcgatat gatttttggt ctctttggct tattagggtt tcaatttagt
     8761 ccaagaattg ccaatgataa aggaaccaaa ctttggcgaa tcgacgctaa cgctcactac
     8821 ggggaacttg atacgttgtc tcaaaattca attaatatgg aactgattta tacccattgg
     8881 gaggacattc ttagggttgc aggttcgttg aaatctggaa aagtgaatgc aacagaatta
     8941 acgaaatctc ttcaacggaa tgggcaaccc acgcctttag gaaaagcaat aactgagtat
     9001 ggaaaagttt ataagacgaa acatcagctt cgttatattt ctgacgaaat atatgcacgg
     9061 caaattttag aacaattgaa taagggggaa gctcggcatg ccttatgccg taatattttt
     9121 tatggacgaa aaggaaaact ctaccagact tattatgatg ggatggaaga gcagctcaat
     9181 gcattaggat tagttactaa tgccatcata tattggaact cactgtattt agaaaaagta
     9241 tttgaacaaa tgaaagctga aggattcgac tgttccgaag aaatgatacg caggcaatct
     9301 ccactaatta gtgatcacat caattttgtt ggtaagtata cgtttagata cgaagctgaa
     9361 ttatccaacg gtaagttacg tccattgaat gtagaagaat tctagcaatg ttcgggtttt
     9421 gcatgctacc gcactatttc gtatgactgt tccagcgaat cacttcgaat agaaaaagag
     9481 aaaaacacga gaacagcgtt aaatcaacgt ttcttgtgtt tttacttttg tgctaccgca
     9541 ctatttcgtt tctatgttcc atgtacccct ttatcaagaa gcgcaaacac gccaaattgc
     9601 cgattggttg atcggcatga acgcaagccc tttatatacc ttgaatttac aacaaaaagg
     9661 cgtacaaggt acattttcat taggacgtgt acaaacaccg actttatatc tcatttatca
     9721 acgccaggaa gcaatagaaa actttaaaaa agaacctttt ttcctgaata attcatagtt
     9781 ttactaatag tctttcctaa cattgattta atagtcttta aagggttctg ttgcaaagtt
     9841 ttaaatctac tatcaaataa ggtagaataa tagaaaaaga tagcaggagg aatgacgatg
     9901 aatcatttta aaggaaagca atttcagcag gatgtgatta ttgtagccgt gggctactat
     9961 cttcgttata accttagcta tcgtgaagtt caagaaatct tatatgatcg tggcattaac
    10021 gtttctcata cgacgattta tcgttgggtg caagaatatg gcaaactact ctatcaaatt
    10081 ttgatttcaa accattgggt cttgcgatta aagaagcccg tcttagtaaa ggattgactc
    10141 gtgagcaggt aggatcaatg atccagattg cgccacgcta tttgacgaac attgaaaata
    10201 aaggacaaca gccaagtttt catgttgtat atgatttagt gactttgcta aatatttctt
    10261 tggatggatt tattttaggg gaagaaaaca gtcataaaag ctccaaacgt cttcaagtag
    10321 aagcacagtt ggattgtctg gatgaagatg aattagtgac gattgggaaa gtgattcaag
    10381 caatttacgg agaaaaatgt aaatttaact agttcaataa tacacaatgg attaattaat
    10441 actatcagga aagattgatt acaaagatgt aatgaatttt ttctgatttt tgttaatcat
    10501 aaatagaaaa tgaatttatc tttgttacac ttaggaacta gagcgaatga taaatagttc
    10561 tttggttact cttatcgctg caaagtacag ttcatttttt gttgttggga aaattttctg
    10621 gatttattgc atatcacttc atccgactaa aaatttttga ttcccatagc gaagttcgtt
    10681 tttgttcctt aggaaaaact tgactgatat actagttttg aaatgacgag taactctgta
    10741 cttcatcaat aatcaagtat tgaattttaa ttgtatactt tttatgcttg agggatgtct
    10801 actgtaatac agctactgca aaaaaaatca gtacacttat tttcttataa aggatatcaa
    10861 gaactaagct caatggtatg catagaaaag aaaaagccga taaaatgaga ttttgatatc
    10921 tcgaattatc ggctctgcgt ctttgcgtct ggctctgtaa ttacagttat tctaaacttc
    10981 gttatttcaa ttaaaatttc ttgtctgcat ttaggacaaa atagagggaa attttttaat
    11041 tcagtatctt ccctcatttt taaacgggtc ttattgccac atatagggca cagtatccac
    11101 ctagtattta caatatctat atcctcctgt tctaattaac aactcaatat tcattttaaa
    11161 aatttctctt tagttcacta tcaatgtaag ttgattttat taaacatatg ccttactttg
    11221 tctattctat tatttggacg acgtggttgg aaagcagact taatgttagt aacctgataa
    11281 ccttttaact ctgttaaaca gacactgcgt ccatttgtaa agaaagttaa actgtttcga
    11341 tactcttgaa tacaacgggc tggaatttca ccaatgagaa tgacctcgtt accttttaac
    11401 ttagtattta aaatatttgc acaatatttg gaagcatcat tatatgctct cgaaagatat
    11461 tcttgtggta cataaatttc gaagctaaga tatggctcta ataactctgt accactcttt
    11521 ctaaaagcct gctctagtac aataggcgca agcattcgga aatctgctgg cgtactgaca
    11581 gggctgtaat atagaccata cttaaaacag atcttacagt ctgttaattt ccaaccgtac
    11641 aatccttgtt cacacccata gcgtatacct tccataactg cattttgaaa tgattgattt
    11701 aaataaccta gagaaaccag gctctcatac tgaatgccac tacccaaagg aagtggtgtt
    11761 acagataaac caatagaagc ccagaaagga tttggaggta cttcgatatc aatggtaaat
    11821 tcagattttt ttaatggtct ttccatataa atgacagttg gttttcttgt ttctatctca
    11881 atatgatatt tttcttgaat cagagtacaa gttacctcca tttggacctc acctaaaaaa
    11941 gatagcacaa tttcgtgagt tactgtatct acataatatt gtagaagggg atcactatcg
    12001 gatatttcaa aaagtgcatc tagtaacttt tctctttgta ctgatttaca tggttcaatt
    12061 gttgtttgta acataggaag aggattctca agaatttctc tatgtggtaa tcttttttta
    12121 tctccaagta cgttatttag ttttaaaagc tcatttttta aaataataat ctcaccaggc
    12181 tctgccttat ctatctggcg taattctcca tttattgaag tatacatttc tgtaactttt
    12241 attttttcct tttctgatat attgactgag tctcgcaaat gtagcgttcc actataaaga
    12301 cgtacataga caagccgttg accatcatct gaatattcta ctttaaaaac atttccacaa
    12361 agtttatctg aattgagttg tgtgggtgaa aataatttgc tagtaattac ctctataagt
    12421 tgtttaattc caatattatt ctttgcactt ccgtgataaa caggatataa ggagcaactt
    12481 tgaattcttt cgttttcctc cttttcaagt tctgcaatat tcaatgtttt cccaatggta
    12541 tatttttcta ataaataatc atttcccaca attactgtct cccattgttc tggttcagta
    12601 taatctatta cataaggttt caaatttaga ttcacagtct gcttaattat gatgtcgtca
    12661 gaaagtttgt ccttaatatc ttgataaaca tctggcaaat ttattccatt ttgatcaatt
    12721 ttgttaataa aaaatattat aggtatgttc atctttctaa gtgcatggaa tagtatacga
    12781 gtttgtgact gtactccatc ttttgcagag attagcaaaa tagctccatc caaaacagat
    12841 aatgaacggt atacatctgc caaaaaatcc atgtgtccag gagtatctac aatatttact
    12901 ttaacatttt cccgttgaaa agatgttatt gcggtctgaa tagtaatacc tctctggcgt
    12961 tccaaaaaca tagtatccgt tttcgttgta ccgctatcta cacttcctaa ctctttaatt
    13021 gctccgctac tgtatagtaa gctttctgtc aaagtagttt ttcctgcatc aacatgtgct
    13081 aagataccga tattaataat tttcaatttt atttcctcca ttcaaaagct caaaaagcag
    13141 aaaaaatccc agtgataaat actcttatca ctgggatttt aatacaaaaa tagctgtata
    13201 ctacacactg atagccacag atgctttatg ataaaatgat aaaagtattc ttaaactggg
    13261 cacaaaaaac cagtccttat tttaaataag gatgcttaat taattattcc cgctatctaa
    13321 ttgacagttt atttaagaat accttgccgc atttttatta tctccttttg aatgttatct
    13381 taattctatc atatgataga atgcttgtaa agccaaccat attttttgaa cgaaagggaa
    13441 attaatgaga aattaatgga agttagtgta gtagttgaag ataactcttc agaatggcta
    13501 tcaaaattca gcgatttaat aacgatttac aagttcataa gggattcttt attcatccag
    13561 ctattatatt acttttcagg tcaataggac aactgtccac aacctttcta caaatatatt
    13621 acgtataatt tttgaaatat atactgctta acaaaatatt ttgcagtggt tccaatagtt
    13681 ttgaattgtt aatattaagt ttgacttgga aaatatcatt
//
LOCUS       DADQCX010000075        13587 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.075, whole genome shotgun sequence.
ACCESSION   DADQCX010000075 DADQCX010000000
VERSION     DADQCX010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.075"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            214..498
                     /locus_tag="J8R83_002059"
     CDS             214..498
                     /locus_tag="J8R83_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAZ9575181.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="J8R83_002060"
     CDS             complement(779..1198)
                     /locus_tag="J8R83_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAZ9575182.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="J8R83_002061"
     CDS             complement(1200..1784)
                     /locus_tag="J8R83_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAZ9575183.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="J8R83_002062"
     CDS             complement(1831..3306)
                     /locus_tag="J8R83_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAZ9575184.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="J8R83_002063"
     CDS             3487..3798
                     /locus_tag="J8R83_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575185.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="J8R83_002064"
     CDS             complement(3913..6249)
                     /locus_tag="J8R83_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9575186.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="J8R83_002065"
     CDS             6391..7059
                     /locus_tag="J8R83_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9575187.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERVGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="J8R83_002066"
     CDS             7062..8105
                     /locus_tag="J8R83_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9575188.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="J8R83_002067"
     CDS             complement(8342..9223)
                     /locus_tag="J8R83_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9575189.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="J8R83_002068"
     CDS             9382..10110
                     /locus_tag="J8R83_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAZ9575190.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="J8R83_002069"
     CDS             10266..10583
                     /locus_tag="J8R83_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9575191.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="J8R83_002070"
     CDS             10576..11184
                     /locus_tag="J8R83_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAZ9575192.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11200..12030
                     /locus_tag="J8R83_002071"
     CDS             11200..12030
                     /locus_tag="J8R83_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAZ9575193.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            12168..12656
                     /locus_tag="J8R83_002072"
     CDS             12168..12656
                     /locus_tag="J8R83_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAZ9575194.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="J8R83_002073"
     CDS             12707..13579
                     /locus_tag="J8R83_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAZ9575195.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
BASE COUNT         4188 a         2377 c         2787 g         4235 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag tgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atacttt
//
LOCUS       DADQCX010000076        12981 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.077, whole genome shotgun sequence.
ACCESSION   DADQCX010000076 DADQCX010000000
VERSION     DADQCX010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.077"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="J8R83_002074"
     CDS             complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="J8R83_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAZ9575196.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1197..3038)
                     /locus_tag="J8R83_002075"
     CDS             complement(1197..3038)
                     /locus_tag="J8R83_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAZ9575197.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3220..5613)
                     /locus_tag="J8R83_002076"
     CDS             complement(3220..5613)
                     /locus_tag="J8R83_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9575198.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5720..6580)
                     /locus_tag="J8R83_002077"
     CDS             complement(5720..6580)
                     /locus_tag="J8R83_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAZ9575199.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6639..7271)
                     /locus_tag="J8R83_002078"
     CDS             complement(6639..7271)
                     /locus_tag="J8R83_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAZ9575200.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            7480..8199
                     /locus_tag="J8R83_002079"
     CDS             7480..8199
                     /locus_tag="J8R83_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575201.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            8225..10816
                     /gene="mprF"
                     /locus_tag="J8R83_002080"
     CDS             8225..10816
                     /gene="mprF"
                     /locus_tag="J8R83_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAZ9575202.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11004..12191)
                     /gene="tuf"
                     /locus_tag="J8R83_002081"
     CDS             complement(11004..12191)
                     /gene="tuf"
                     /locus_tag="J8R83_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAZ9575203.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            12559..12915
                     /locus_tag="J8R83_002082"
     CDS             12559..12915
                     /locus_tag="J8R83_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9575204.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         3727 a         2715 c         2309 g         4230 t
ORIGIN      
        1 tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt caatagtcca
       61 cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca attttcttaa
      121 tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaatactt tccctacttc
      181 ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga cattctcttc
      241 ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact cataagctgc
      301 gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt gagagtcatc
      361 ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca agatttctcg
      421 gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag gttctcttcc
      481 aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt caaccatatg
      541 aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg cttgacgaat
      601 ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc
      661 cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc ctcgtcctac
      721 ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac gctgtttcgc
      781 ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg cagttaaaag
      841 ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt ttacaccggt
      901 tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac tcttcaagct
      961 gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt caatcttttg
     1021 gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct gattggataa
     1081 atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg ctactgctgc
     1141 ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt gagtagctat
     1201 ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc aagctcaagc
     1261 tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt tatttcatca
     1321 gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg cgaactttct
     1381 tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc atcttgcaaa
     1441 aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc atcgaataaa
     1501 aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt taaaatatta
     1561 cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt ttctacttgc
     1621 gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc
     1681 tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc
     1741 gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc ttgttcgatt
     1801 ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat cttgtctttt
     1861 tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg
     1921 cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag atattcatca
     1981 ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt ttgccgaagc
     2041 aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc
     2101 aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact tgtccccata
     2161 gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat aaacccttcg
     2221 aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag attaaataaa
     2281 acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg ctgatctttt
     2341 tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa
     2401 ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc atcatcatgc
     2461 gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt cttgaatact
     2521 tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc aattaattct
     2581 aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt tgtatgcaat
     2641 agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt ccccgtagca
     2701 gattcaggat tttggacagc tatagtacgc tgacgccatt gatcttctaa cggtatctgt
     2761 tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag ttcttgaaga
     2821 aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct
     2881 gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa gtaattttta
     2941 ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt ttgactgcgt
     3001 actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc tgctctattg
     3061 atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa atcgcactaa
     3121 ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat catatttcat
     3181 tgctttttca agtataacac atttctatct cattaagcat caatttgcta ctcttttcag
     3241 taactgattt tgaatatcag ccttccagta caatactcga agaacaatat ttacgagcat
     3301 gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca aaattccatg
     3361 gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga agatgcgcaa
     3421 tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa tcagcaagta
     3481 atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa gtagatacac
     3541 cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa gtgctgtagg
     3601 caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga aggaaggata
     3661 cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa atccaattgc
     3721 tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa aaaagatgcc
     3781 tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt ctggcaatgt
     3841 agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc catcaccttc
     3901 tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca caccgtcgcc
     3961 tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt tcttttgctg
     4021 cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt ccatttcttc
     4081 agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac gtctagcgat
     4141 attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac cttcctcatg
     4201 aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt caaacagagc
     4261 aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag cgatccccaa
     4321 cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc
     4381 ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa attccatcgc
     4441 gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc gattagaaag
     4501 ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt ctgccagata
     4561 cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt ctacccgctg
     4621 gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg tatcgacatg
     4681 ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg ccagtttggt
     4741 tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa gcatgcctaa
     4801 caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga tgaacagtgc
     4861 ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt
     4921 gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct cgctagtcaa
     4981 gcggacagca taattatctg cacctactcg gataacttca gccatgacag aaccgcttgt
     5041 caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat cagattcgcc
     5101 tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat cggctggtat
     5161 ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag tagaaatcga
     5221 ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg ataatttccg
     5281 tacaagattt cttgcatgta tttcttgata aattccaata acgatattga cgacaataat
     5341 tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc caataccaaa
     5401 gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg tactttttga
     5461 tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta cctcttgctg
     5521 tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa taatcacgtg
     5581 tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt tatagaaaaa
     5641 cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt
     5701 ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc caccaaccta
     5761 gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact cccaatcccg
     5821 cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa atgaaatgga
     5881 atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat ccaagaacac
     5941 aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct ttaaatccgt
     6001 cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc aatcctggga
     6061 cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa ttctgatcga
     6121 cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga acaaaagtaa
     6181 caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct ttccataacg
     6241 caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt tcatacgcac
     6301 ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg cctagaccaa
     6361 caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct aaaaaagaaa
     6421 tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact cctggcaaga
     6481 taaatcctga accgataaac attcccttca caaaccgtaa catccagtct ttggttgtgt
     6541 accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgca ctccttcttt
     6601 catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac tttttcatag
     6661 gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt acctccatta
     6721 tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg gtattgtttc
     6781 ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc tgctaattct
     6841 actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc aaaattatat
     6901 gcttggacag ctgtccataa atcgcatcct tgtttctttg cttctactat catttccgcc
     6961 aaatatttga caccttgatc aatactgtca gctggattat caatgatctc agcttctcca
     7021 tgcagacttt ccgagctctg catgagatct gtcccttttc cttttgattc ggtcaatatt
     7081 atcgccttga tcaaattctc gtagttttcc atatgataat tttttgcagc tgttgttatt
     7141 tctatttgat agctttccac tcgttttacc gaacgataag ttcttcctcc taaaaacaac
     7201 accgcaccaa taaccgtcag aatgatcatg taaaaaagaa tacggataat agataatcgt
     7261 tttcgcttca tttcatcacc tagttatttt gacatctttt tttatcttac tatttcttta
     7321 tcttcttggc tatttcttcc ttgatttctg tgtacgcctt aagaaaaaat gaattttcct
     7381 gtattttttg acatcttacg aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg
     7441 actgatataa tcgttatact ttacacagta ggtgattatg tgaaaaaaga aaagaaatat
     7501 gcaaaaatgc cagatgggag cgaaatttac tatgaaaaga gcggtcaagg cttccctctc
     7561 tttttactgc atggcaatga cggcagcggc cgcttttttt cagaacaggt ccctgtactc
     7621 gaacgctact ataccgtgta tctagtagat agccgaggac atggtcgttc gacaaacgaa
     7681 gcatctatgt tgaattttca gttaatggcc gaggatctga atacgatcat gttgctggaa
     7741 aaaatcgatc aggcagattt tcttggattt agtgatggag caaatctagc actggtattt
     7801 gccagcagct tccctaaaaa agttcatcga ttgattttaa attctggaaa cacgcttgtt
     7861 aaaggcgttc gtttttctgc cagagtcatc agtaatattc attatgcatg ggtatggtta
     7921 ctctctttat ttcgcccaag tcttcgcaaa aatcttttag ttatcaaact tttgctgcat
     7981 gacatcgggc ttacagaaaa tgatttaaaa aaaatcaact cccccacttt gatcatcgtg
     8041 ggaaaaaaag atgtaatcaa gctaaaacat tctttgtata tagctaaaac tataccaaaa
     8101 gcttcctttg tgcttgtgaa agaacaagga catgaattag ctagaaaaga tcctgaacgc
     8161 ttcaatcgag aagttcttca atttctttct gaaacataac tattaggaat agaaggtgat
     8221 ttatttgtta aaaaatacca tacaatggct gaaaaaccac ctaggactgt tcaaaacaat
     8281 ctttttgatt tctgtcattg tcattattgt cggtgaattg atgtccatcg gtaaaactct
     8341 atctatccag caattaggag aaacgtttgc cactatacct gtatggaaaa gcggactaat
     8401 gctattgatt ggtcttatct ctgtgttacc tatggttggt tatgatatta ttttgaatcg
     8461 gatgcttgaa caaaagcaga atcctcgtta cctgtttgag acaagctggc tgatcaatac
     8521 gatcaacaat attgccggtt tcggcgggtt tgttagtgtg gggcttcgct ctgaactata
     8581 tggacaaaag aaagagagca gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt
     8641 gatggctgga ctttctattt acagtctgct ttctttttta cttgtagtct tcacgccagt
     8701 tgctcctttt ttgaagcaat attggatatg gttgatcggc ggcggtctat attttcctgt
     8761 cgtcttttta tttactactt tcaaaaagaa aggattcctt ggtggtacct cacttaaaac
     8821 tcaaggacag ctattgctag tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct
     8881 ttctgttggt tatttaatgg aaatccggat tgatctgtgg caaacaattc cattattcat
     8941 tgctgcttca gtgataggaa tcgtgtctat gattccagga gaaattggga gtttcgatgt
     9001 aatgatgatt atcgggttgt ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat
     9061 cttgctctat cgcctgttct actacatcat tccgtttttg attggaatcg tctttttctt
     9121 caaaaatatc ggttccactt ttgatcagcg ttattctggt atccctaaac aattagcaac
     9181 agaaattgcg cataaaatcg tggttgtctt attatacttt tctggaatca tgctagtact
     9241 ttctgccact atcccgcaag cttttacaga gtttcgctgg cttcatagtt tgaacccatt
     9301 gaaatttcat tttattatcc aatttcctag tatactattg ggatttcttt taatcattat
     9361 gggcagaggg atcgcagcac gtgtgaaacg agcatatttg cctacaatct tcttgattgt
     9421 tctagcttta ctttatgttt tattaagtga ttttagtttc acaccggtgg ttttcttgtc
     9481 tattctgctt ctgatcattc ttgcttctaa aaacgaatta tttcgggaac aattgatcta
     9541 ttcatgggag tggcgtacga tcgatggaat cattattggt gcactgtcct tgctttacat
     9601 cgttattggg gtatacaatc tgccagattt ccctcatcgg cgtcaccatt ttatttcctt
     9661 tttcttattt ccttctgaaa agatttggtt ttcgggattg ttggccatca tcgctgttag
     9721 tttcatgatc gttctatttg ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc
     9781 ctttaatgaa gaaaaggccc tgaagatcct tacaacttat ggaggaaact ccgatagtca
     9841 attgatcttc ttaaaagata agcggatgtt tgcctatgaa aaagacggtg aaccaactgt
     9901 tcttctccaa ttcgcttgct tcaataataa atgtattgta atgggtgatc cttctggtaa
     9961 gaaagaagat tttccagaag caatcgaagc ttttatcgaa gaaacagatc gactatgcta
    10021 tttaccagtt ttctacgaaa caagcgaaga gattgttatg attttgcatg aattcggcta
    10081 cgatttcatt aagatggggg aagaagctta tgtagacctg aatagtttta caacttcagg
    10141 gaaaaaaatg aagggcactc gtgctgtctt gaatcggatc gaacgagaag gatttacatt
    10201 tgatgtctta caaccaccat tttctactga gcaaatgagt actttcaaaa atatctctga
    10261 taattggttg ggttcacgaa aggaaaaagg gttttcttta ggctttttct ctgaagatta
    10321 tctacaaaga gcgcctattg cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc
    10381 aacgatcatg cctacttaca cgaacaataa agtaggaacg attgatctga tgcgatatga
    10441 ttctaaaaaa gcaccttctg gcagtatgga tttcttgttc ttgcatttgt ttgcctatat
    10501 gaaagaagaa catatccaat ggttcaattt agggatggcc cctctttcaa atgtcggaac
    10561 ttccagaaag agttttttac aggaaaggat tgcatacttg gtttacgagt ttggttctca
    10621 tttttattct ttccatggat taagagaata taaaagcaag tacgctacaa actgggtctc
    10681 acgttatact ctatattcta gagatagttg gattgcatat gttatgattg ctttgctgat
    10741 tattgataat gcgccagttg agcagacaca aggtagaata agtggtttga aaaaatggat
    10801 acgaagaaag tattaaaaac tgcataccga tagatgaaca ctctcatgat gaataaaaga
    10861 gactgaagta aaacgaaagt tcatgcttct acaatctctt cttatacaat tgaagaacaa
    10921 agagcggtcc aaacagaaat cctgtttgga ccgctctttt attttaaaca tttttcatta
    10981 ccaaaatatt cgagtcgcgt ttcttatgct tcgatctctg taacgatacc tgaacctact
    11041 gtccgtccgc cttcacgaat tgagaatgtc gttccgtttt caacagcgat tggatggatc
    11101 aagtcaacat caatcgtcac gttgtcacca ggcatgacca tttctgtatc ttctggcaat
    11161 gtgattgttc ctgtaacatc agttgtgcgg aagtagaact gtggacgata gttgttgaag
    11221 aatggagtat gacgtccacc ttcttctttt gtcaacacgt acacttctgc tttgaatttt
    11281 gtatgtggag taatggaacc tggtttagca agtacttgtc cacgttcgat atcgtcacgt
    11341 tggatccccc gtaacaacac gcctacgtta tccccagctt ccccgtaatc taacgtttta
    11401 cggaacattt ctacacctgt tacaactgct ttttgtgttt caggtttgat ccctacgatc
    11461 tctacctcat caccgacacg aacagcacca cgatcaatac gacctgaggc aacagttcct
    11521 cgacctgtaa ttgagaagac gtcttccact ggcaatagta atggtttatc tgtatcacgt
    11581 tctggtgttg ggatatattc atctactgta tccatcaatt ccataatagc agcttcagca
    11641 tctggatcgc cttgcaatgc ttttaatgcg gaacctttga tcacaggagt gtcatcgcct
    11701 gggaaaccat attcgctcaa taactcgcga acttccattt ctaccaaatc gatcaattct
    11761 tcatcatcga ctaaatcaac tttgttcaag aaaacaatca ggtattttac accaacttgg
    11821 cgtgacaata aaatgtgttc acgtgtttga ggcatcggac cgtcagttgc agaaacaact
    11881 aagattgcac catccatttg tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt
    11941 cctggtgcat caatatgcgc gtagtggcgt ttttctgttt catattctac gtgtgcggta
    12001 ttgatcgtaa tcccacgttc acgttcttct ggagctgcat caatactagc atagtcttga
    12061 ggatttgcta ggcctttttt gcctaatact gtagtgatcg cagcagttaa agtagttttc
    12121 ccatggtcaa cgtgtccaat cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt
    12181 tcttttgcca taatttacaa acctcctaaa taatatagat cactgaaaaa tttcagctct
    12241 caccttttta ttatagtctt tttttgacta aatcaaaaag aatacgtccg acttactttt
    12301 tgtaagattc gaactaagct tattatacgt caatattggt caaagtcaac taagagcact
    12361 cgtctgtctt atacgcgaaa aaagtacctt ttataaataa aaaaatgtgt tttttgagaa
    12421 aaacttcaag atagtcctta actttctttt gaagcaataa gaacaaaatg aggaaaagtt
    12481 taaaattcag ctgttgccaa caactttcaa tagacgaaat cttctatttc gttaataata
    12541 aggaaagagg tgaagtacat gaaaaaatta attggcgtac ttgtcgtttt aggcatattt
    12601 ctcggcggaa gttttgcagc ttatcattat ttttacggcg gcgaagctta ttatacaaaa
    12661 atcacgacga atggcgaaat gtcagctacc caagcagata acggagagaa attcacgact
    12721 tatacctaca agcaagcggc ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc
    12781 gaagaaagag aacatccatt aaagatgaat gcgtatctta aactcaaagt caatcctcgt
    12841 aaaggtgtat taagctggga agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa
    12901 aaaatcgata attagtaaat ggtcttaaaa ttttattaga taaaaagagg ctgggacaga
    12961 agcgtttaac tccaagaaat a
//
LOCUS       DADQCX010000077        12723 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.078, whole genome shotgun sequence.
ACCESSION   DADQCX010000077 DADQCX010000000
VERSION     DADQCX010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.078"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..153)
                     /locus_tag="J8R83_002083"
     CDS             complement(<1..153)
                     /locus_tag="J8R83_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAZ9575205.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFN"
     gene            563..2935
                     /locus_tag="J8R83_002084"
     CDS             563..2935
                     /locus_tag="J8R83_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575206.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNDQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQVPEKEQKQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGHTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQD
                     EKNVVETAEQKNIVLVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDTQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2996..4456
                     /locus_tag="J8R83_002085"
     CDS             2996..4456
                     /locus_tag="J8R83_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAZ9575207.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPDWLIDYAEKEGLIAELKPKHERQNF
                     LVQDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEMKVEPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGKQQERE"
     gene            4467..4910
                     /locus_tag="J8R83_002086"
     CDS             4467..4910
                     /locus_tag="J8R83_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HAZ9575208.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQ"
     gene            4995..6671
                     /locus_tag="J8R83_002087"
     CDS             4995..6671
                     /locus_tag="J8R83_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAZ9575209.1"
                     /translation="MNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRNFQ
                     KEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVETE
                     KKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAIQGLYEGKYLSYPRTDTPYITEGEY
                     AYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQLS
                     PLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPLDLGWKKLFGKES
                     DGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSEEA
                     QSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLTSA
                     EMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAAS
                     EKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEIIQN
                     SRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTAK"
     gene            6917..7513
                     /locus_tag="J8R83_002088"
     CDS             6917..7513
                     /locus_tag="J8R83_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9575210.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDTERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            7526..8425
                     /locus_tag="J8R83_002089"
     CDS             7526..8425
                     /locus_tag="J8R83_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAZ9575211.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKEQKLAYQRHQQMNREMER"
     gene            8428..8912
                     /gene="ssb"
                     /locus_tag="J8R83_002090"
                     /pseudo
     CDS             8428..8912
                     /gene="ssb"
                     /locus_tag="J8R83_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            8934..9191
                     /locus_tag="J8R83_002091"
     CDS             8934..9191
                     /locus_tag="J8R83_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575212.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(9350..9484)
                     /locus_tag="J8R83_002092"
     CDS             complement(9350..9484)
                     /locus_tag="J8R83_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAZ9575213.1"
                     /translation="MLKSIKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK
                     "
     gene            9627..9887
                     /locus_tag="J8R83_002093"
     CDS             9627..9887
                     /locus_tag="J8R83_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575214.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            10336..10542
                     /locus_tag="J8R83_002094"
     CDS             10336..10542
                     /locus_tag="J8R83_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAZ9575215.1"
                     /translation="MRKKFDYLGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIEEKGKKR"
     gene            10542..10793
                     /locus_tag="J8R83_002095"
     CDS             10542..10793
                     /locus_tag="J8R83_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575216.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGCELHYQENLETYENEYWLTKLEN"
     gene            10809..11246
                     /locus_tag="J8R83_002096"
     CDS             10809..11246
                     /locus_tag="J8R83_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575217.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCFEIGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            11682..11870
                     /locus_tag="J8R83_002097"
     CDS             11682..11870
                     /locus_tag="J8R83_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575218.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IACIGQYLYCIRGRKLYA"
     gene            11928..12194
                     /locus_tag="J8R83_002098"
     CDS             11928..12194
                     /locus_tag="J8R83_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575219.1"
                     /translation="MGTGFIDRVLVQVKEERKITMKYNLLDHKRMWVEKLEEDLEQLE
                     LLGHNKTSTVYKEGLKRTKKAQKELATLESRVQKKEVDLTHTYL"
     gene            12204..12437
                     /locus_tag="J8R83_002099"
     CDS             12204..12437
                     /locus_tag="J8R83_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HAZ9575220.1"
                     /translation="MADKRKEKIQKLLALAADVNDEESVSALAKAQQLMMDYDLTEDE
                     IFNYHEQQRIEAVETHVIYRGRPQKWLYRLFRN"
BASE COUNT         4703 a         2136 c         2661 g         3223 t
ORIGIN      
        1 attgaattca agaattgttt ctcgtatgaa tgaagcacct tcgatgtcat tggcaacaga
       61 gatttcagat aagatagaca attgattgtc gtctgttaaa aaacaaacat ctagtttttc
      121 agagctaacg tcaataccga caaataattt catggaagaa ggacctcctt tcgatataaa
      181 ttttggaaaa tgcttcgata ctgtgggatt tcccagaaac tcactgtata gccacaacct
      241 cgcctaatag aatacggtga taaaagagct agaagctgcc ttccaaacta ctatttgaaa
      301 gtctagtcca ttatcgaaac agctaatgag ttggtagtga taacagtggt tcgggtaaca
      361 gactgaacag ggtagacaaa cgctacagga ggaaatagca aattcccgtt ggatcctttc
      421 catacatcca ttgtactctg agaaatcaca caatatcgaa acaaattccg ttaggaatgt
      481 gttattcaat aaattttata atctagaaac attttgaata aaaactatta gacaaatgat
      541 attttacgag gaggaaacgg acatggcaga agaaaaagaa ccactagaca atagtcgttt
      601 gggaaaatcc aaaagaaaat tagtacgatt gcaaaatgaa ttaaatgatc aaatcgaaaa
      661 gatgtttgaa caccaaagaa agaccaacgg tcaaccaatg aacgataaga gaaacgggca
      721 ttcttggttt aggcaacaag aacgaatcga aaataaagtc caaagtctga gagaagagat
      781 caagcaacaa gaaaaacagg tagaaaaact tgaaagacaa gaagagctaa aggaaatggg
      841 ttataacaag tacggtggcc tggatatgac gatcgaaaat attccaagaa tcaaagaaga
      901 aatcgaacgc tttgaaaaag gtgaatcgac tttttcagct gccacgatcc gaaaatacca
      961 acgaaaattg gaaacattag aacagctgaa agaaaaatca gagaaaggaa aagaaaatat
     1021 tcttcctgaa gtacaagcga tcattgacag cggacgagtg acgcaatgga aaaagaatcc
     1081 aactatctat tttctgaaag gctatcgaaa agtcgcttta gaactcaatg aaaacggggg
     1141 atttgaggaa tctaaaaaat accaagccac gtcggaagaa gaaaaggcag ctgttcgtga
     1201 attacttgaa gaagctacac ctactgattc tgtgaaggag aaagaaaccg atcatttcta
     1261 tcgagtagaa ttcaacgaaa atgatccagc aaaagggttg aaaagttatg gtggggagat
     1321 cgtaacacta gaattgatcg atcaactcaa aacactggat aaccaatacg ccgcagaagc
     1381 aggctattat aaattctatt ttgaagaagt gaagaatgga gaagtagtag atcagatacg
     1441 aatggatcta ggggatggcg tcaatagtaa tcaccccatc tatttagagt tagctagatt
     1501 gtgcgaacaa gtacctgaga aggaacaaaa acaaacagtc aaaaatgaac ctatttcaaa
     1561 agtacaaaat gagattaaag agacaaaaac aaaacaaaag ggttatcaaa aacgaacggc
     1621 agaagagatt aagcaagaag tcaaatcact ttcccaacag gcgcttgatg cggtgaaaaa
     1681 gcatactcat tcacctgaag acgtcaaaga acttttgaat tttatgtctc gttttccaga
     1741 acgatccttt agaaatcaat tattgatcga ggaacaattt ccaggcgcaa cggcttgttt
     1801 aggtcgtgcc gcgttgaaaa aagaaggaat ctatatcaaa aaaggggaac aagggaacaa
     1861 gatctttgtc agaaaaacgg tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga
     1921 aacagaggct acaccagaag ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa
     1981 aaaaccttac tacacgattg aaaaagtgtt tgatatcaca caaacacaat tgaagcctga
     2041 agactatccg aaaatcttcc cgaaccgcgt ctttgatttt caattggatc aaacagggca
     2101 tacagaactt caagttggga ttcaagcggt agccaaaaat attggaattc aaattcgaga
     2161 tatgacagaa agtgaagtct atcaaagaga attaggacaa gcacgtgggg cgtacgttcg
     2221 taacgaattt actggcgaag aagaaatcgt catgaatact cgaaatactc ctacgcagca
     2281 tttagccaca agtattcacg aattagccca tgctagaatg cacaaatttt cagaattaga
     2341 tactgcaaca aaagaactac aggcagaaat gacctcctat attgtgtgca agcattttgg
     2401 gatggacacc tcggagaaag ctattcctta tattgcgaca tggacgaaga atggtcagac
     2461 gttggatgat aaggaagctg cggaacgtgg gaaaatcatg aatgatgtca gtcgtgtcgc
     2521 aaatgaattc attcaaacca tttctaatga aatcaatcaa tacagagaaa gagaaccaga
     2581 gatccagcca gcagaagtga agcaggatga gaaaaatgtt gtagaaacag cagaacaaaa
     2641 gaatattgtg ctcgttggct cactttggat cgacaagaaa gacgggaaag tcctggaaga
     2701 agacacgggc cgaacgttac atttgaagga tgcggcgttt attgaagata cgcagcataa
     2761 tcaagtgatt ttaaaaggaa aaagttatgg aaaagagatt caaacggcgt taccttcaga
     2821 agaatttgcg ctaggaaatc cattccgatt ttcacttgaa acagtgtcag aagtggccaa
     2881 acgaaaaaat gaaatctatt atgaacaaca attgtcacaa aaagaacgcg tataaaacaa
     2941 gtaaaaaaga ctatctgaaa aacggatagt cttttttctt ttgggaggtt tgaaaatgac
     3001 cgagaaaaaa atgagtctta ttgatcgatg taaacagatc gatatagtgg attttgctcg
     3061 aaacaatgga atggctgtag tcaataaagg acgagactat cgcttagaag accatgattc
     3121 atttgttttt gatcgaagaa aacaacgttt ttattggaac agtcaaaata ttagtggcga
     3181 cattattgaa ttagctaaac tttttttcat agacaaagag attcaagact ctaagcaaca
     3241 atttaaagca gccacagatt ttattctaaa gaatgaagac aaaacagaac gagtagaaaa
     3301 tcttcatttt gagacagaaa agtacaaaga tcaccccgtt gattatcaac cactcacaga
     3361 aaaaggaagg aattatttga aggaagaacg aaaactgccc gattggttga ttgattatgc
     3421 agaaaaagaa ggattgatcg ccgaactaaa gccaaaacat gaacggcaaa atttcttagt
     3481 tcaagacgat cgtttggatc atgcggtcgc ctttttatgg aaagatccac agacaaaaga
     3541 gacagtaggg gcgagttatc aaggaacatt cattgattat gaacgttttg gtgagagagg
     3601 cacatataag catatagata aaaattcgac agcgaatcat ggatttaacc taaagatcgg
     3661 tgaccctaaa cagttaaaat tttttgagag tagtattgat ttacttagct atgctgcact
     3721 gaatcgtgat cagttaaacg atacgtggtt agtctctatg gaagggttaa aacaccatgt
     3781 gatcagtcat tattttggtg aggcagtatc tgaattgaga aagaaacaag cctttcctca
     3841 atccattgag atttgtgtgg ataatgaccg tgcaggacat attttctacg aaaaagaaca
     3901 attaatgggc gcagttgatc catttacgaa tcagaaagta cgttgtgaac gaggaatcgc
     3961 taatgattgg caagtgccaa aagaatacaa agtcatttat gaagaagttg caaaagaaat
     4021 gaaagttgaa cctgaagcaa ttatggccat acacaagaca gaaaacaatc tgcaattaac
     4081 gaaccaactg gtttccgctc acaaagtaaa tgcgtctttt ggtcagcagc tttctgttaa
     4141 cgattcaata gaagctatta atttgaaaga tatttgtaga gaagtcgcaa aagaattaaa
     4201 aggttgtgaa cgcgtggatg gtacgtacga ttttgatcgt ttttatcaag aaaaagggga
     4261 tattaatgct cagattcttt tctcttataa agcagaacaa tactacaaag gctataaaaa
     4321 tcatgaacat gaatttgtac ctgaagtaaa aaaggattgg aatgatcaat tgaagcatga
     4381 aatccaccaa caagagatca gaaagcaaaa acgtgcgatg ttgtttcaac aaggcaaaca
     4441 acaagaaagg gagtgaaatc gtcatgatga aaaccgttat tttagcagaa aagccgtcac
     4501 aagcgaaagc ttatgccgat agcttctcta aagccacccg aaaagacggg tattttgaaa
     4561 tccaagatag attgtttcct ggtgaaactg tgatcacgta tggttttggt catttagtcg
     4621 agttagattc gcccgatatg tacgatgaaa attggaaaca atggtcatta gagcatttgc
     4681 ctattttccc tacacattat cactatcatg ttcctaaaga taagaaaaag caattcaagg
     4741 tggtgaaaca gcaacttcaa tcggccgaca ccattattat tgcgacagat agcgatcgtg
     4801 aaggggaact gatagcttgg acgatcattc aacaagcagg cgccgatcat ggaaagatat
     4861 ttaaaagact ttggatcaac tccttagaaa aagaagccat ttatcagtga ttccagcaat
     4921 tacgagacgc agaagagacc tatcccaaat ttgaagaagc acaagcacgc cagatcgctg
     4981 attggttgat cggcatgaac ggcagcccac tgtatagttt actcttgcag caaaaaggca
     5041 taccaggaag tttttcctta ggcagagtcc aaaccccaac gctttacatg atttatcagc
     5101 tgcaggaaaa gattagaaac ttccaaaaag agccttattt tgaaggaaaa gcccaagtaa
     5161 tcgctcaaaa tggcgcattt gatgcgaagc ttgatccgaa tgaaacccaa gcgacgcaag
     5221 aagcatttga agattattta aaagaaaagg gggttcaatt gggaaaacag ccaggtacga
     5281 tccaccaagt tgaaaccgag aaaaaaagtg cggcaagtcc acgtcttttt tctctatcca
     5341 gccttcagtc taaaatgaat cagctcatga aagctagtgc caaagatact ttggaagcca
     5401 tacaagggtt gtatgaaggg aaatatctaa gctacccacg aacagatacc ccttatatta
     5461 cagaagggga gtatgcgtat ctgttggatc acttagacga atacaaacac tttttaaagg
     5521 ccgaagccat tcctactcct attcatacac cgaatagtcg atatgtgaat aataagaaag
     5581 tccaggaaca ttacgcgatc attcctacaa aaacggtcat gacggcagcg gcttttgaac
     5641 aattaagtcc actgcagcag gccatttatg aacaagtgtt aaaaacaacg gtggccatgt
     5701 ttgcggaaaa atatacctat gaagaaacaa cgatcttgac gcaagttcag cagcttcagt
     5761 taaaggcaat cggaaaggtg ccgctagatc taggttggaa gaagttattt ggaaaagaga
     5821 gcgacggaaa agagaaggaa gaagagccgc tacttcctaa agtgacaaaa ggagaaatgg
     5881 tgacggtgga tctacaagtt cttgaaaaag aaaccaagcc accacaacct tataccgaag
     5941 gtacgttgat cactgcaatg aaaacagctg ggaaaaccgt ggatagtgaa gaagcgcaat
     6001 ccatattgaa agaagtggaa ggaatcggta cagaagcgac acgggcgaat attattgaaa
     6061 ccttgaaaca aaaggaatat atcaaggtag agaaaaataa gctcgtggtg acgaataaag
     6121 ggattttgct ttgccaagcc gtggaaaaag agccgctgct tacgagcgcc gaaatgaccg
     6181 ccaaatggga aagctacttg ttaaagatcg gtgaacgaaa aggaacacaa accacttttc
     6241 tagccaatat ccaaaaattt gtctctcact tattggaagt cgtaccaggg caaatccaat
     6301 ccactgattt tggatcgacg ttacaagaag tgaaagcagc cagtgaaaag caagaagccg
     6361 cgcgtcattt aggaatttgt ccaaaatgcc aggaacaaga agtcttgctc tatcaaaagg
     6421 tggcagcttg tacgtctgaa gcctgtgatt ttaaattatg gacaacgatt gccaaaaaga
     6481 aactcacagc gacacagctg aaggagatca ttcaaaatag ccgaacaagc caaccagtga
     6541 aagggttaaa aggtcagaag ggttcatttg aagcaacgat tgttttaaaa gaagacttca
     6601 ctacaggctt tgaattttct gaaaagaaaa aaacgaactt caagaaaaga acacgccgca
     6661 ctgcaaaata atggagggtt aatcttatgc gtaataccac acacaaacaa caagaaatcg
     6721 aaaatcaaaa agccaaaatt cgttcagaac aggaaaaaat gcgtgccagc aaacgaagac
     6781 tgcagcaatt gaagaaccag cagaggattc aaaaagaaat cgaattagat cgataaaatc
     6841 ttcctaacta ttgtatacgt ataaacttat gttatactgt ttttataagt ttatacgtat
     6901 acaaaggagg gagaaaatga caaaagcaat ggtatacaag ctgctagaag aatttaatgg
     6961 aactttggct ttgaaggatg ccaaaaaagc gggcatttct cctgtaacga tcaaacgtat
     7021 ggtagatcga ggggagctgg atcgagagta tccaggtttt ttcaccttac ctggtcaatt
     7081 tcctgatgaa ttgtttatgg cgcaaaaaaa atatgaacgc ggcattattt cacatattac
     7141 cgcgttagat ttgtatgatt taacagatat gatccctaga cagatcgatc tgactgtacc
     7201 ttacggttat cacgtttctg aaaaaggatt gaaggaattc gcagttgagc tacactatac
     7261 aaaagcggaa tggtatgaat taggtaagat tgaaataaaa agtcgctatg ggaatcctat
     7321 tatagcttat gatacagaaa gaactttatg tgacatttgg aatccctggt ataccgttga
     7381 ggatgaaatc aaagtaaaag caatcaaaaa ctatatggag tcggacagaa aaaatcttag
     7441 aaaattgaat gagtatcgac gaattttacc aacagacaaa acgatgcgtt cttatattat
     7501 ggctttaaat taaaggagaa gatacatgac acctacgcag ttaaaagcaa aagtgaagaa
     7561 tatttctaga gaaaaagaag ttgatccgca gcttgtttta agacatttta tgatggaaaa
     7621 attcttggaa aaaatctcag agtctcctta tcgtgaaaat tttgtgttaa aaggcggctt
     7681 cttgattggc tcaaagtatg gcattgaaaa tcgcacaacc aaagatattg atacgacttt
     7741 acgggaaatg aaagtaacca aagaaacatt aacaacggtt ctaaacgaaa ttttttcaac
     7801 gccgacgaaa gaaggcattc aatttgagat tcaaggaatg aaagaaacga gagaagccga
     7861 ttactatcca ggatttagct tacgtgtgct ggcacatttg gaaaacatgc ggccagattt
     7921 taaggtagat gtgactacag gtgactcgat ctatcctgca acgatcactc acagtcataa
     7981 attgatgttt gaggatcgaa cgattccttt ggaatcctat cctacagaac aaattattgc
     8041 tgaaaaatta agtgcaacct ttgatttttt aacagataat tcgagaggaa aagattttta
     8101 tgatctctat actattccta aaatggagaa gatcgatgag aagaccttga aagatagtgt
     8161 gagaaataca tttacacgtc gaggaaaaac tgatccgtta aagatatact atgaaaagga
     8221 tatggatgta ctgaaaaata gtcacgagct aaaagatacc tggaagaaat atcaaaaaag
     8281 caatccttat gctgcatcga tcacgtacga tgagacaatg gattcgatta gtaatttgat
     8341 ggaaaaagtg attcacgtcg aagaaaaaga gcaaaaacta gcttatcaaa gacaccaaca
     8401 gatgaataga gaaatggaga gataaagatg attaataatg tgacattagt aggacgctta
     8461 accaaagatc ctgatttacg ttataccgca agtggtactg cagtagcgac ttttacccta
     8521 gccgtcaacc gaaatttcac gaatcaaaac ggcaatcgag aagccgattt tattaactgc
     8581 gtgatttggc gcaaaccagc agaaacaatg gcgacattag ctaaaaaagg tagcttgatt
     8641 ggtgtagttg ggcggattca aacgcggact tacgacaacc agcaaggaca acgtgtatat
     8701 gtgactgaag ttgtagcaga taactttcaa ctattagaaa ataaagcagc gacagagagc
     8761 cgtgcgcacg ctgatcaatc gtccaccagt ccaagcaccg ccacctttga acaacggata
     8821 cagcgacgcc taacaacaat ggattgaacg cttcacagaa tccatttggt ggacaatcaa
     8881 tcgatattag cgatgatgat ctaccgtttt agtttgagaa agaaggagta agcatggcaa
     8941 aaaaaattag tctgacgatg gatctattga tacccgtaat tgcatttata gacgggattt
     9001 ctttgggcgt cactgaaaat cctttggtaa atagaattgc gaaaggatca ctatttcttg
     9061 tattcgtgta tcttgtctgt tcttatcttt taaaaagagc aggaaaggat aattcctttt
     9121 ggcgattgac taaagtcaca gtagcagcga cagctgttat acttacggct attctaccgc
     9181 tttatatgta gagttaacgg gaaatcgttg aacttcttgc gaaatattgc tataatgaac
     9241 atgaaaaaga ggagttgcgc taacaacccc tcattaacag caccgattaa agaacggtgg
     9301 cagaatatta gttatttgga aataaccgct gacctgctaa agtagacggt tatttctttt
     9361 tgtcattttt aagcatattt acaatcaaac taatcaaagc aatggtaaac ataccaaaac
     9421 caagaatggt ttgaattgtc tcatatgcgg acaaaaggct tactcctttt atagatttta
     9481 gcacttacat tcataagcac caccaccttt ccagaagtcg ccaccgtctt caaactttac
     9541 tgtcttgact attatagcat atctaaaatc gaataaaaat tctcaatttt aactgttttt
     9601 gctataattt tagcgaggtg atcgtgatga acaaatatgt tggtttgctt gataaaatcc
     9661 gagtaataaa aacacaacca ttattggttc gctttacttt acaaacaatt catgaatcga
     9721 ttaattgtgt agttgcagat attgaaatta tcgataaatt gttaattatg gatgatggaa
     9781 aatacaatat tgccgtcaca ggtcatttca ataaacggaa tcaattagtc attgaatcga
     9841 tgcaaattag aaaccctgat cattttacgc gatcaatggg catataaata aaagaagagc
     9901 tgcaatccta atgtaggact gcagctcttt ttgttttaca tagaaacagg aagaaaggga
     9961 aaggcctgtt taggaaggca caagtgcctt ctcaattgaa aaacctttct ctcactccaa
    10021 ccgccaccgc cgttcgagaa gaaaggaagt gaacgttgca cgttcactaa gataaggggt
    10081 cttgctttgt aagacaaaat aggaaaagct tcctctcacc aaaaggttcg ttcctgttcg
    10141 ctatctcttt attgatttgc cagaccggca acaagttgcc ttttatcacc aaaaagcgac
    10201 aaggacaagg gtaaatggca cgctgcgcgc ccttgtcctt gtcgcttttc gttgattcat
    10261 tctggccaac aaatcaataa agaaagaact aacgaaagga agtaaaacct ttcctaagag
    10321 gaggcagaat caatcatgcg aaagaaattt gattatttgg gtgttccctt cagcgaatta
    10381 ttcccaaact atcatgcacc acatactgtc gaatgcgatt gtggagaaag agcgaaatgt
    10441 atcaaaagct attgtttgta tcaatgtcca acatgcggga aaaaatatac cttgtcttat
    10501 ggcgattata ttttgattga ggagaaagga aagaaacgct gatgaaaaca caacacaaat
    10561 tattgactgt aaaagaagtc gttcaaattt tggtggacaa agaagtcatt tctgaaaaag
    10621 tagcagaagc tttacttatt ccgcggtact ggacgataga aaccccttta gtagaggatg
    10681 caccgactat gctatttgaa gacctagtga agattgcagg atgtgaactg cattatcaag
    10741 aaaacttgga aacttatgaa aacgaatatt ggttaaccaa attagagaac taaaaaggag
    10801 aaaaaaatat ggctcaaaat tactatgacg aatttgtcaa attacctttg gataaaatgg
    10861 cacaaaaaat ggaggatatg acgttcctat acaacgaaac acgtgttcca aaaaaacatt
    10921 ataaagaaaa attgtcggta gctgtggaag aaatgattga atcaggtgtc gaaatgaatc
    10981 ttattgcgac gtactatcga acactggaag aactgaaaaa gcaaaatgca aaatggtttt
    11041 tccaagcctt actatgcttt gaaataggtg tcaaaccaag cactattaaa ccttctgaat
    11101 accaggcttt agaactaacg tatgcgaaat ttatcgaaac gaaaaaagcc aagactgttt
    11161 caagtgaatg gttagattat tttgaaaata tcaataagta tggcgcatat tacaccatga
    11221 aaaaggaaga caacgaaaat gaataaggtg atttatcaac taacaacgga ttccatatca
    11281 acgatttgaa agaaaaaaag gtcaataatc atttataccg aaaagtgaga atgtgtggaa
    11341 taaggacaaa aaaagcctag taactaaggg aatggttctt atttcgcacc aaccgccccc
    11401 gccgcttagg tggtgcgaaa taaacgggca aagcccgata acttaagaga aagaaggtga
    11461 tccatttgaa aaagattatt cccttattgt tagtactgtt tgttggcgaa atacttatgc
    11521 gagatagtgc agctgtacag ttaaacctcg ctgtattttt ggtaatactg gtgttttgtt
    11581 tgatcttttg gcggtttgta ttagtcctcg tgagtctact attcaagatg attgcagcca
    11641 tatttttcat ggggttattt cgatgaaagg agagagtacc aatgccaatt gcaataggaa
    11701 ataaacggtt acccgtgaca ttagatgaaa agagacaaaa agaattgcag caactaaagc
    11761 agaagtacgg caaaagtgaa tccaggatta tgtgtattgc gttagattta ttgattgcct
    11821 gtattggaca atatctctat tgtattcgag gaagaaagct ttacgcttga atgcgataag
    11881 ttaacccgat atatcgatcc aaaattctat gaggataaaa acctggcatg ggaactggct
    11941 ttatagacag agtgctagtg caagtaaagg aagaaaggaa gatcaccatg aaatacaatt
    12001 tattagacca taagcgaatg tgggtagaga aattagagga agacttagaa cagttggaat
    12061 tgttaggtca taataagact tcaacggtgt ataaagaagg actaaaacga acgaaaaaag
    12121 cacaaaaaga actagcaaca ctggaaagta gggttcagaa aaaagaagta gacttaacac
    12181 acacttacct ttaggagtag aaaatggcag acaagagaaa agaaaagatt caaaaattac
    12241 tggcgcttgc ggcggatgta aatgatgagg aatcagtgag cgcattagcc aaagcccagc
    12301 aattgatgat ggactatgat cttactgaag atgagatttt caattatcat gagcagcaac
    12361 ggatagaagc agtagaaacg cacgtgatct atcgtggacg tccgcaaaaa tggctgtatc
    12421 gtttatttag aaattaagat aaaaaaggct agttaacagg tttgttgact ggcctttttt
    12481 gatatgtttg tacatgtttt attgtgtttt aatttttctc ttttttatag caagctcctt
    12541 ttataataaa tattccgaaa agtgaagacc attttttatt tattaagact attattatta
    12601 gtgagataaa atttgattga tcttacagaa tattggtgac gattatgaca ctaaagatac
    12661 tatttatgaa aattttgcaa aaatgttctg aaaattacat ataattgttt tataaaaaag
    12721 gga
//
LOCUS       DADQCX010000078        12521 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.079, whole genome shotgun sequence.
ACCESSION   DADQCX010000078 DADQCX010000000
VERSION     DADQCX010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.079"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            718..1689
                     /locus_tag="J8R83_002100"
     CDS             718..1689
                     /locus_tag="J8R83_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAZ9575221.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(1767..2003)
                     /locus_tag="J8R83_002101"
     CDS             complement(1767..2003)
                     /locus_tag="J8R83_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9575222.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1972..2103)
                     /locus_tag="J8R83_002102"
     CDS             complement(1972..2103)
                     /locus_tag="J8R83_002102"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9575223.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2179..2562)
                     /locus_tag="J8R83_002103"
     CDS             complement(2179..2562)
                     /locus_tag="J8R83_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAZ9575224.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2595..3380)
                     /locus_tag="J8R83_002104"
     CDS             complement(2595..3380)
                     /locus_tag="J8R83_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAZ9575225.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3558..4658
                     /locus_tag="J8R83_002105"
     CDS             3558..4658
                     /locus_tag="J8R83_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9575226.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4648..5472
                     /locus_tag="J8R83_002106"
     CDS             4648..5472
                     /locus_tag="J8R83_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAZ9575227.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5478..6284
                     /locus_tag="J8R83_002107"
     CDS             5478..6284
                     /locus_tag="J8R83_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9575228.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6281..7111
                     /locus_tag="J8R83_002108"
     CDS             6281..7111
                     /locus_tag="J8R83_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575229.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            7118..8149
                     /locus_tag="J8R83_002109"
     CDS             7118..8149
                     /locus_tag="J8R83_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575230.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8256..9529)
                     /locus_tag="J8R83_002110"
                     /pseudo
     CDS             complement(8256..9529)
                     /locus_tag="J8R83_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9756..9941
                     /locus_tag="J8R83_002111"
     CDS             9756..9941
                     /locus_tag="J8R83_002111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575231.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            10065..10781
                     /locus_tag="J8R83_002112"
     CDS             10065..10781
                     /locus_tag="J8R83_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAZ9575232.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(10689..11622)
                     /locus_tag="J8R83_002113"
                     /pseudo
     CDS             complement(10689..11622)
                     /locus_tag="J8R83_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            11910..>12521
                     /locus_tag="J8R83_002114"
     CDS             11910..>12521
                     /locus_tag="J8R83_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9575233.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCI"
BASE COUNT         3616 a         2317 c         2841 g         3747 t
ORIGIN      
        1 aactagatca tcaatcgtaa gcatcgcaaa ttgatttcta ccattcgtat tgtttttaga
       61 catcatagct atcactcctt gcattcgttt tcataaatct attataaaag aaaagactgt
      121 agacatcatc cataaaatgg actttgtcta cagtctggat aacgtgattt tttgctgtaa
      181 tgacaaggtt ttagctgttt cagataccat gtatccaaaa atagtttatt gagaaaatag
      241 gagagtattt gatactaact agtaggaaaa aatgagataa aaagtaaatg gaatcattta
      301 aggtaatctg aaataaaaaa tatacagccc tgtggtactt tacctacaag gctgtatata
      361 ttttttactc tcagcgtttt tgactccgtg tctgactccg ttttattgat tttgaatgtt
      421 attcaatgac catttaacag gtcaaatttg atgtttttga ttccgtatga cgccgtttga
      481 tatctagtga tatagtgatt tgagtctaca tcgaataagg gaataaacca ataaaaaatg
      541 atttagaata ttaaaataac aaaaaagagg actacctgta ttagtcctct tttttgacca
      601 gattttgacc agtctatttt acatcctagt atatttatat gagctaattt tatgattaaa
      661 tggtaagttt ttccttgtgt gttttagttt aaactagtgt gtaattcaaa aatctatatg
      721 gaaggaacag tattaagaat agaacagggt tctctacatg atggtgctgg tttacggacc
      781 gttgtttatt taaagggctg cccattacgc tgtgcctggt gttcgattcc cgaatcacaa
      841 agcaagcaga ttgaaaaagg atttggccag accatgaccg ctgaagaggt aatggatgag
      901 attgagaagg atgctgtttt ttactttcac tcggatggcg gagtgaccat tagcggaggc
      961 gaggcactgg ttcaggcgga ttttgctaaa gaaattttgc aaaaatcgaa atacattgga
     1021 atcaataccg tactggaaac cagcttttgt ggtgcttata atgaaatcca aaaggtagct
     1081 ccctatgtgg atacattgtt tgtggatgta aaaatgttta ccagcaagct ccacaaacaa
     1141 tggaccggct tagataacca acaaattttg aagaatattc gtcgcttttt aattgagtat
     1201 cctaactgcg aagtgcgaat tcgagttcct gtggttccag gtatcaatat gaacctgacc
     1261 gagctgctga cgattgcttg ttttgtggca gatcttgatc ggttcgtacc gttagaatta
     1321 ctaccgtacc actgctatgg tatgcacggt taccaagcat tgggactgga gtatccgttg
     1381 gcagacacgc cagcgccttc acctaaagaa atgtttgcat tggcagatca actggctcgc
     1441 acggttcctc atttgctggt cacagcttta accaaaacat ttatttattt attgaatcca
     1501 agctttatct tatggataaa tgaaagacac tcactagctg cagccagctc aagaatagag
     1561 cttttgctga agtcagtgag tgtcttttta cgatgttttt tcgaagttaa tttgtcgaat
     1621 gaacactggc tcaatcggta catcttcact gtttgtcggc tgagctgcga tcgctgctac
     1681 gatttctaac ccttggtata cctgtccaaa aacagtataa cgaccatcca gctccggtag
     1741 tcctccaagc tccaagtatg cttgctttac attagcaggt cagcctgcgc ctttgtgttt
     1801 tgcacaataa aaaactggtt gccgttggtg tgggggccgt ggtcccctaa ggccaaggcg
     1861 ccattaaaat gataaagtcc gcgatgcact tcatcagcga aaaagccctc atagctggaa
     1921 acagcttcat caccagaacc atccaaagcg ccaccttgaa taacaaattc cttaatgaca
     1981 cgagccgaaa ggtgtgttgt cataaacgcc ttgctcagct agggagcgcc agttggctac
     2041 agccagggga gcttggtcag gaaataagcg gagacgaatt tcaccagcat cggtgaccag
     2101 cacacaaact tcttcctgct gcggtttttc taattgaaag agaggaaggt ttgcaactga
     2161 aacgccttga tcctgccatc aaatatcgaa aatccgccac tcgaccttcg cctgatcacc
     2221 aaggcgagcc attcccaata aaacggtata ggcggtttca tccgcttgaa aggtcaattg
     2281 cagctgtcct cgtaaatcgt tgtagtcatc tggggcggct acttgataaa aaagatgaaa
     2341 ctgcgcatgc aaatattcca aaggctgatc tttaaaggct gcaaaataag cctgaacttt
     2401 ttcccgctgc aagctgtcag ccaccaaaaa attttccagt tgttgttttg gaacggctgc
     2461 taacaaggat cggcaaaccg cctcaatttt caacgcatcc caatgtcgcg caattaaata
     2521 atggatgggt gcctcttgat tgtagtccca caggttgctc atttttttca ccactttctt
     2581 ctattatata ggaatcacaa aatcggcagc ggcgtcaggc ggcgttcttt tccttgaatg
     2641 actagcaact tttctacctg acagtctgcc aacagctgac tcattttttt aaagcccagc
     2701 tgataatctt cggcaacatg agcatccgag cctaaggtaa agagctttcc gccgacactt
     2761 tgatacaaag gaacggcata acggtaaagg tcttcgttgc cgtatttcaa gaagctcttg
     2821 gcatttaact ccatcgccaa ttctcgttca acaacctttt tgaaaatcgt tagcagctga
     2881 gcctcaaaat gctccgcgaa ttcttccgct gtgaaggtga agcggcgtaa tccataatca
     2941 aagtgagtca aaatatctcc ttctggaaaa tccgtcaaga cctgcaacat ctgatcaaaa
     3001 tattccttgg tagtttgaat gggatctttg gttaaaacca catcgtccat ataatcaaag
     3061 cggccatttt gatgaatact taccagcttt aaatcataag gatgctgagc gaggtaatcc
     3121 acgatccgct cttcttgtcc tggaacaacg ccaatctcga tacctcgcag aaatttggtg
     3181 gaataggttt cttttaaaga gtccagtttg tttatatagg ctggataatc cggaatgtca
     3241 tcttttccgg tagatggatt gtttaaatca aagtgatccg tagaaacgaa aaactccggc
     3301 tgataggcta aatagttttc aaatttttcc tctgaatcaa aggaaaaata cgtgtggaga
     3361 tgctgatcat aatactgcat agggagcctc cttttttcta ctatcatacc gcaaaagctt
     3421 tagaaggtta acgggaattc gtcgaaattt acaaaccata tacaaccttt acattgttca
     3481 tgaaaccttt tcaagaaact gattctctca ttacaaagct ttgttagaat ggaattatcg
     3541 aaaggggaga agaatgaatg aaaatgaatg aaaaaattcg taacatgact atcggtttat
     3601 tttgtgcagc aacagtaagt atcctgctga caggctgcgg ctcaggtgaa gcaacgaagc
     3661 aatcggctgc ggcagacgac tctttagata cgattataga aaaagccaag gaagaaggag
     3721 agattgccag cttgggaatg ccggatactt gggcaaattg ggtaggcact tggaacgacc
     3781 ttgaaaaaga atacggctta agtcacgtgg atacggatat gtccagtgca gaagaattgg
     3841 ctaagtttga atcagaagga aaaaatggaa ccgccgatat tggtgatgtc ggtatcagct
     3901 tcggtccgtt ggctgaaagc aaagagttaa ccttacctta taagaccaac tattgggagg
     3961 aaattccgga ttgggcaaag gatgatgatg gggattggtt gttaagctat acgggaacca
     4021 tttcctttat caccgataaa gagaatgtga agcaagcacc gactagctgg aaggagctgc
     4081 aagagggtga ctatcaagtt agcgtggggg atgtgacgat tgccaaccaa gcacaatttg
     4141 ctgtattggc tgcggcgatt gccaacggag gtgacgaaaa ggatattcag ccaggtctga
     4201 attactacaa aaaaatggca gaaaaaggcc gtttgtccac cgttgatgcc agcgtagcaa
     4261 atcttgaaaa aggtgaaatc gatgtggcag ttgtttggga cttcaatgga ctaaattatc
     4321 gtgaccaaat tgactccgag cgttttgagg taactgtgcc aacagacggc tccatcatta
     4381 gcgggtatac aaccttaatc aataaaaatg cccctcatcc caatgcggca aagctagcac
     4441 gggaatatat tttatctgat gaagggcaaa tcaatttggc aaagggctat gcgcgaccta
     4501 ttcgcaaggt agagctgcct aaagaagtag ctgaaaaatt actgccggag gatgcttatg
     4561 aagcggcggt gccagttgaa gacaatgaag cttggaacaa gacctctgta gagcttccag
     4621 agctttggca ggcggaggta ctgacctatg caaagtagac ttgacaaact gattgtagtt
     4681 atactagacg gctgtcgcta cgacacagcc gtcgcccagc ttgggttcat gaatcattta
     4741 gttgagcacc agcaagcaag cttattgaag gtaaaaagtg agctgcccag caattcacgt
     4801 ccgttatacg aagtactgat gaccggcgtt ccagcctatg aaaatggcat ctatagtaat
     4861 taccatgctc agcgatccaa agagtggtcg ctgtttgaat tagttaagga agctggcgga
     4921 aaaacaggag ccgccgctta ccactggtac agcgagttgt acaatcaagc cccctataat
     4981 cgtttggttg atcgcatcca gcatcaggag gagcgactga ttcagcatgg catcttttat
     5041 agtgaggaca cttaccctga ttcgcattta tttgcggatg cccattattt agtgaatcag
     5101 tatcagccag actttttggt cgtacattcg atgaatattg atgatgtcgg tcacaaattt
     5161 accgccgatt ctcatgaata tgcagcagcg gttaatcagg cggacagatt attggctatt
     5221 taccttcctg aatggctgca aaaaggttat caagtcgtgg tgactgcgga tcacgggatg
     5281 gatgcgcacg gactgcatgg cggcagcttg gctgcacatc gtgaagttcc tttttatttg
     5341 atttcaaata aacgccaaaa gctgaaggaa caaactgtac cacagctgct ggcggctcca
     5401 ttgttttgct ggttattagg aattgcaccg tcagagaaaa tgcaggacat tcaagaattg
     5461 atgaggggat gaaagagatg aaaaaacgct tggttctggt tcctgcctcc tttatcttct
     5521 gtgcattttt actgctgccg ctgcttttta tggttctgtg cagcttgcac agtgatttaa
     5581 ctaaccagtg gacattggcc aattacagtg atattttcag caacaaatat tacacacagg
     5641 cctttgttaa cagcgtactg attgctgtca gctccagtgt gattgggtta atcgggacgt
     5701 ttattttatg tttatgctta atgaatctat cgactaaatt gcaggagaaa atcacctttg
     5761 tttccaattt ggcagctaat tttgctggga ttccgctggc attctctttt attattttgt
     5821 tggggaatgt aggtgtgctg aaaatgattt tgccatttct agcggacttc aatttgtatt
     5881 cttggtgggg attgaccatc acgtatacct atttccaaat tccgttaggg gtcttgtttt
     5941 tgtatcccag catgaaggaa gtgaaaaagg aatggctgga gtccgcacaa ttgctgggcg
     6001 cttcatcagc gtatgcttgg ttcaaggtgg ctttgccttt tttgcgacca tcgattgcca
     6061 gcacctttgt catcttattt gctaatggca tggggaccta tgaaacagcg tatgccctga
     6121 ccagcagtaa tgtaaatctt ttaacgattc gaattgcggc tttagtgtcg ggagatgtgt
     6181 tcgccaagcc taatttaggc agtgcgttgg cagtcgcttt aggtgtcctg ctggtaacgg
     6241 caatgttgat tattcaaaag aaaggcaagg tggtgcagac gtgaaaaagt taataaaacc
     6301 gattttgttc tgctttgtcc tgtattactt gctgccgatt attggaacga ttttgtatgc
     6361 cagctccact aaatggtcaa aatcgctttt acctagtgat tttaccttgc aatggttcca
     6421 acagctgctg acggacaggg aatttattgc tgcggtgggt cgctcacttt tattagcagg
     6481 tgtggtcttg gtgacgattc tgttgttgat gattcccacc attatttgga ttcatttgta
     6541 tttccctcgt ttgaatcgtt ggctggaaaa gctgctcctg ctgccgtatg ctttaccagg
     6601 agtgattttg gtaacggctt tgcttcgaac gtatgctgaa actggtatcc caatgtttgt
     6661 agtgttggta ggtgcattgt ttattacggc gttgccgatt gtctatctta gtcttaacaa
     6721 ccagatgcgc ttaattaatc tgaaggaatt agtggatgca gcagaaacct tgggcgcccc
     6781 gatgtctacg attattatcc aggtgctgtt tccaaacatc cgtatcggtg tgaccctagt
     6841 ttctctgatg attttttctt cggtttttgg ggagtacatg ctgacgaacc tgttgattgg
     6901 cggtcgattt cagacggtac gcatctatat gctgcggcgg atgaacgaaa acggccattt
     6961 ggctagcgct gtgatggttt tgtatttgct gtttatggtg ggaattgctt taactacctt
     7021 tatgctgact tatcgacaaa agcaacagct gtcccttaag cagacgaggg aagagaagca
     7081 gtcgaaaaag aagcccttaa aggagttgtg acggaaaatg tttttagaaa tacatgatct
     7141 caatctgttt tttgatgaaa aacagatttt agctattgat gaaattcaga ttgaaaaggg
     7201 tgagctggtt actttactag gtcccagcgg gtgcggaaag tctacgttgc tgcgctgtat
     7261 cacgggattg gaacaaccaa agagcggtga gattgtgctg gacaatgaga atattgccga
     7321 taagcctacg aaggatcgca atatcggctt tgtttttcaa cagtatgcat tgtttccaac
     7381 tatgactgtt tttgaaaatg tagcctttgg tttgaaggta aagaagctga gtcctgaggt
     7441 gattcaggaa aaggtttttg agatgctatc attggtggat atgacggagc aggcagataa
     7501 aaatgtccag tttctttctg gcggtcaacg acaacgggtg gcactggctc gctcattggt
     7561 cactgaaccg aaagtcctgc tgctggatga gccattaagt gctttggatg cccgaattag
     7621 aaaacagctg cagcgggatt tgcgcgctat ccagcaatcg ctagggatga cgatgatttt
     7681 tgtgactcat gaccaagaag aggcgatgcg aatcagtgat cggatttttg tgatggaagc
     7741 tgggcgggtg gctcaggttt ccacctcgaa ggaattgtat cagaatcctc agagccgatt
     7801 tgttgcggaa tttatcggca actataatcg tttcgaatgg tatgagctga atcagtatac
     7861 ccacgagttt tccgctaagg gcaatcgctg catttattat ttaagaccgg agctgattca
     7921 atttgaaccg gttcctcagg gggttaagat tccggttcta tggaaggaat catttatttt
     7981 aggcaacatt caacggtatg tttttcaaac gctggagggc aaagaaattt tagtggatcg
     8041 gttgaacgat cgggaagaga aaattagcga tgccttatac attcagctga aagatattct
     8101 agcaatccct gtggaaattg atactcagca ttttgcacaa caaagctagt gtatagtcgg
     8161 caaacatttc tggctctttg tcaaatagga ctgatagagt gatataagaa catctaaggt
     8221 agaattgatt ttctgcttta gatgtttttt tatgtttaat aagtgatcag atgattgatt
     8281 aagaaaattc tggttctcat cctaacccgt aagctattcg tttcaatgct ttgatgtggg
     8341 tatgcagatt ttctattttg ccatttgagt aaggcaactc taaggctaaa cgaatgccgg
     8401 attcatagtt tataaacgct ttttttatat gatgcagttc tcttggaacc gacttgggca
     8461 ttgtttttac aagctgaaag aagatgtccg cttctttgtc ataaaaagct tgaagaattt
     8521 cttgatagta agcataagct attcgtagtt catcagaagt agaaagtaga cgttctacga
     8581 cttcactttc ggttaaatag gcccaaccaa aattacgcca ttttgtccat ttatcataaa
     8641 caagcgtgtc ctgtcgtttg atcagaagtc gagataaagc cttcacttgt cgatagtgtt
     8701 tggcttgtat tggatcgttt cggtcgaagc ttttcatgac tcatagtcaa atatccttaa
     8761 aactgcgaat gaggtgcttg acgatgtgaa agcgatccac aacgagtttg gcatgaggaa
     8821 agcactcttt tatcagcaaa gcataagagg cgttcatatc tgttacgagt atttttacgt
     8881 ttaaacgtgc acgtcgttca aattgcataa aataagaaat gagatctttc ttcttacgtg
     8941 aaggaagaat atccagtaat ttcccagtat cgccatccat acaagaaaaa gaatagggac
     9001 cgacttgatt tttcaatgaa cgaaattcat ctaccaatga acagcgaggc aaccaattta
     9061 ttttcacgtt tgtcatgggg agcagagaag cgagtgttcg cgaaacggtt gaccaagaaa
     9121 cgccgcaatg tttagaaatc gtcgtcattg cttgtttttc agtcaattcc tccaatattt
     9181 tataatgtac ttgtttggcg ataaaacagt ttttttcaac aatgtaggta ttcgccgtaa
     9241 aataggtgtg acagccacga cagaggtacc gttgctttgc caaagcaaga taagtccgtt
     9301 gattcgcaca cttattgaga aggaccagcg attttttctt tccgttctta acgatcagcc
     9361 catgttgatt cacctgttta cactgaggac agggctgaat cgttttaatg agcgtggcag
     9421 aaacaacgat actgttgatt gaatgtattt ttttcttctc gacatgagtg atttgaatgt
     9481 ttccatcttt gattcctagt aatagtttga taagatgaag atcaggcata cagaacgctc
     9541 ctttgattgt gttgtggtga ttcaattcta acggagcttc tgtatgtttt gtttttttat
     9601 gctcaaaagg actgatagaa tgatttacta tcagtcctag aaattatagc gccacatttc
     9661 tttcaccttt gacttttcag acggcagttt ttatgctgat actgtagaga gagcaggaca
     9721 cagcttttgc ttgttttggg taagggggaa agaagatgac caaagcactt atttttgatt
     9781 ttgatgggac gatgattgac agtgaatgga tgttttacga gagtattcat cactatttac
     9841 tgaagcctat ttactggagc agttcggcta taaaattcct tttgcagact atcaacaagg
     9901 tgttgggacg gcagcagaac tgtcctttta tgaagggata agtcaagcgg ttgggagacc
     9961 agtggatgct gaacattttg agcagcggat cagcagcact ggaaaatcgg agtagtctca
    10021 attctgaact gcgggagcta gactattttt ttgaagcaca tccgatgatt aaggaaaaaa
    10081 ttgattcctt tgtgacgatc gatgatcttc aggtcggcaa accagatcca gaaggttatt
    10141 tgttgtgctt gaaacggctg agggttgaac aggctgttgt agttgaggat agtccagtcg
    10201 gtgcccaagc agcaccgcat atgacagttg atgtacaagc gttggatgca gattttttcg
    10261 cctttagcgg gcataaaatg tgcgggccga caggaatcgg tgtattatat ggcaaacgtc
    10321 aattgttaga acaaatggag ccagtcgaat tcggcggtga aatgatagat tttgtcaatc
    10381 tttacgatag ttcatggaaa gagctgccat ggaaatttga agctggtact ccgaacattg
    10441 caggagcaat cgattacttg aatgagattg gtatggagaa tattcatcgt tatgagcaag
    10501 aactggttgc ctacgtttta cctaaattac aagcgatcgg cggtatcacc atttacggac
    10561 cgcaagatcc tgaacatcat actggcgtgg ttgcttttaa tttggatggc atccatcccc
    10621 gtgatgtggc gactgctctg gatatggaag gtgtcgctgt acgttcagga caccattgtg
    10681 cacaacggtt catcgacgat ttctgtttga ctaattggtc gtttaaacag tcgatgataa
    10741 tgccgtttga gcggctccaa tgtcgtggaa tctttgagta agagtttcca atatcgcttg
    10801 agccgacggt acttcttctg attttcagag tgcgaggctc gaaaacgatt catgatctgg
    10861 atacgcaatt gattgaagct gcgattgata tgttggacaa tatgaaagcg atcagttacg
    10921 atctccgcat ttggaaagac cgttttaagc agctgacaat agctggcatt ctaggtactt
    10981 gacctttaaa cgggcttttc taggaaagtg caggaagtat tgagttagtt tgtaaagtct
    11041 gcgatcttca aggatcgtaa atagctgatg ggttgtccca tcaacacaaa taaaactcat
    11101 ggaactagaa acagacttca ttgatttgaa ctcatccata cacaacaccg tcggaaggaa
    11161 gttcatacgt ggctggtaat gcttcgttgc ttcacgcaag atccgtgtca ccgtcccatc
    11221 cgagacgaag tacttcttag cgattagttt acgtgattga ttttcgtaca gttctatgag
    11281 aatcgcctgc ttcagttcct ttgttagttg atgatgttca tcaactaagt ccgttttcgc
    11341 agaaaaggtc tgcccacaat catagcatag aaaacgggta cgttttaatt ctaaaatagt
    11401 caacttttct ttgactttca acatctgagt acgtgtcgta taggaaccgt tgcggataat
    11461 acgaatcgat ccacagtgtt cacaatggga aggtgagtca tccaatctcc ctttaataaa
    11521 ctgcgcttga acgcctttat attctttttc aatcagccat tcttcatcaa aaaataaatg
    11581 tttatctgtt aatccgagta attttctagt atgattatcc atagagcgac tcctttggta
    11641 gggtgatgtt ttggtcgact aaattttacc aaaagtgagt ctctttttga gttgaaacga
    11701 agaaaaagtg ttagtagaaa atcgccttcg attttccaac aacacaaaat attatagaag
    11761 ccttttttct aaaggatttc aaggtgtctg tttgcattta ttaaaaaaaa gaaaaagtat
    11821 tggcaacaga aggcgtcacc aacactagat attatagagc cataatatgc tgtataatat
    11881 ctagtgtata ggcttaagtg gaggtatata tgaaaatatt aactgttgaa gatgataata
    11941 tgataagaga gggaataagt gaatatcttt cagaatttgg atatactgtt attcaagcta
    12001 aagatggaag agaagccttg tcaaaattta atagcgatat aaatttggtt atcttagaca
    12061 ttcagatacc ttttataaat ggtttagaag tgttgaaaga aattagaaag aaaagcaatt
    12121 taccaattct aatcttgact gcatttagtg atgaagaata taaaattgat gcatttacta
    12181 atttagtaga cggatatgta gaaaagccat tttcattgcc ggtcttaaaa gctagaatag
    12241 attctttaat taagaagaat tatggacatt tagagaagtt tgaatataag gatctatcgg
    12301 ttaattttaa tagctataca gctaaaataa atggtgaaga aatagatgta aatgcaaaag
    12361 aactagaagt attaaaatgt ttattggata ataatggaca agtgttaaca agaatgcaaa
    12421 ttattgatta tgtatggaaa gatagcgaag aaactcctta tgatcgagta atagatgtat
    12481 atataaaaga acttagaaaa aaattacaat tagactgtat a
//
LOCUS       DADQCX010000079        12180 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.080, whole genome shotgun sequence.
ACCESSION   DADQCX010000079 DADQCX010000000
VERSION     DADQCX010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.080"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            611..1939
                     /locus_tag="J8R83_002115"
     CDS             611..1939
                     /locus_tag="J8R83_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAZ9575234.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2141..2974
                     /locus_tag="J8R83_002116"
     CDS             2141..2974
                     /locus_tag="J8R83_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAZ9575235.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2990..3727
                     /locus_tag="J8R83_002117"
     CDS             2990..3727
                     /locus_tag="J8R83_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAZ9575236.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3882..4850)
                     /locus_tag="J8R83_002118"
     CDS             complement(3882..4850)
                     /locus_tag="J8R83_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAZ9575237.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5082..5915
                     /locus_tag="J8R83_002119"
     CDS             5082..5915
                     /locus_tag="J8R83_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAZ9575238.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5949..6788
                     /locus_tag="J8R83_002120"
     CDS             5949..6788
                     /locus_tag="J8R83_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9575239.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6814..7374
                     /locus_tag="J8R83_002121"
     CDS             6814..7374
                     /locus_tag="J8R83_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAZ9575240.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7573..9294
                     /locus_tag="J8R83_002122"
     CDS             7573..9294
                     /locus_tag="J8R83_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAZ9575241.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9459..10601
                     /locus_tag="J8R83_002123"
     CDS             9459..10601
                     /locus_tag="J8R83_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAZ9575242.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10617..11828
                     /gene="thiI"
                     /locus_tag="J8R83_002124"
     CDS             10617..11828
                     /gene="thiI"
                     /locus_tag="J8R83_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAZ9575243.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4151 a         2046 c         2527 g         3456 t
ORIGIN      
        1 tcctactgcc ggagtaaata aagcttatgc aaagaaaaag aaatccaatc acttgggttt
       61 ctttttcttt tattattatg atgaatcaag ctttctgttt ttgtcacgta tgttgtaatc
      121 tttacgaaag agtagagttg gctactcata atcaaccata cttcccatca tcgctaaata
      181 cgaaataaat cagcattcct acaccaatca aagcacaagc tgcaccaaga aaagggatga
      241 cattcccaaa gttatctgta ttcataagta tgccaccacc cacaaacaaa aagccgccag
      301 caatcaggtt tttcatttta ttcatctcct ttcttacgtt atagtatttc cttctttcaa
      361 tgagtatttt gaaagctatc ttattgtatg atgttcttct aggcctcttc tttattatac
      421 aggccatttt cgttatctca tagaaatatt cctttttatc tgaaaactat tgtataccgt
      481 atgacatttt tcttcatgaa gttgtaagta tattctcatt caaatgaaaa tttcatcata
      541 gaagagattg tatttctaaa ttcttaagag taaaatacga agtataactt ggatttggaa
      601 ggatgattgg atgaaagcta ttacgcctga tatgacaaca aaatttaaca aacagtttca
      661 agcaaatatc aaacagcagg cattgcagcg ggcagttgtg aagaacggaa ttactgcttc
      721 tgctgaaaat gtttcagcac atgtggagaa tacaccggta ttttctatag atttggctac
      781 ggggaaagtg gctaatcaaa tgcaatcggg gcgttgctgg atgtttgctg cactgaacac
      841 attccgtcat aagatgctga atcaattcca tttaaaagag tttgaattat cacaaaatta
      901 cacttttttc tgggataaat atgaaaaggc aaattatttc tatgaaaaca tcattgcaac
      961 aggaaaagag gcaatcgata gccggaaagt agctttctta ctcgctactc ctcaacaaga
     1021 tggcggccaa tgggatatga tcgtttcatt attccaaaaa tatggcgttg tgcctaaatc
     1081 ggtgatgccg gaaagtgcga atagttcaaa ttctcgagat ttgaataact acttgaacaa
     1141 attactgcgt aaagatgcag tagtgttacg gaaaatggtt gctcaaggag aaacattaga
     1201 cgctattgaa gaaaagaaag aagaaatgct agaaagcatt tataacttct tagctatctc
     1261 attaggaaca cctccaaaag aattcgattt tgagtaccgc gatgaagaaa agaactatca
     1321 tcttgaccga ggactgacac cacaaatttt ttatgataaa tacatcggtg taaaattaga
     1381 tgattatgtt agcgtgatca atgcaccaac aaaagacaaa ccattcaatc gttcttatac
     1441 agtagagatg ctaggaaatg tcgttggcgg gaaagaagtc aaatatctga atgttgatat
     1501 ggaaactttc aaaaaattag cgattgctca gcttgaagaa ggagaatctg tttggtttgg
     1561 ttgtgatgta ggtcaatctt ctactagaac tagtggcatc atggccttag atgcttattc
     1621 aatggatgat ctatttgata cggattttac aatgactaaa gctgaacgtt tagattttgg
     1681 agaaagtctg atgacccatg cgatggtatt gaccggtgtt gacttagtag acgggcaatc
     1741 aacaaaatgg aaagtcgaaa atagctgggg cgaaaaagtt ggaaagaatg gcttctttgt
     1801 tatgagtgat gcctggatgg acgaatatac gtaccaaatc gttgtaagaa aagatttatt
     1861 gacgaaagag caattaaatg cgttcaatga agaaccaatt gttctatctc cgtgggatcc
     1921 aatgggtgct ttagcataga cgagtatttc aatgaagagt atgtagtaaa gataaaaaga
     1981 gctggcttaa gccagctctt tttatcttta aagtccattc cctgtttttt atggtccctg
     2041 tgctataatt ctaaataaag gataaggatt ggaaataatc cttttatcat taaaaatatg
     2101 atgacgaagt agaataaaat tgggagtagg ggggaaagtc atggatatcc aaactgtttt
     2161 atctgatctg aaattaaatg gtaaagtgat tccagttgtt ggtggcgatg ttaatcagac
     2221 ctatcgtata aaaaccgaac atcgtgctta ttttttaaaa atccatccga atgtaaaaaa
     2281 aggatttttt gaagcagaag tagacggatt aaaagaactg tcagcattcg tacgtgtacc
     2341 ggatacgtat atgctaggtg aaacaagtga aggcgcttat ttgttaatgg aatggatcga
     2401 gccgggaaaa ggggatcaac gagatcttgc tgcagcttta gctaatctcc atcagcaaac
     2461 agcgccacaa tttggttttc gtaaagataa ctatttgggt acacttgttc agaaaaattc
     2521 ttttgaagaa gattggtgga cttttttctt taaagatcgg cttgaatccc agatttcttt
     2581 ggcagaagaa acgaatcgat ggaatgtaca gcgtcaagaa aagtatctgc gatttaaaga
     2641 acgtgtattg aaatcggttg aaccaaaaaa gatcactcca cgcctcttgc acggagacct
     2701 gtggagtggt aatgtgttct ttgaccagca agggcatcca gtttttgtcg acccagctgt
     2761 ttcttatggg aatcgggaac aagatattgc aatgagccag ttattcggtg gtttccgacc
     2821 ggaattttta gatgcttatc aaactatatt tccattagaa aagggatgga aagaccgact
     2881 gccgatttac cagttatatt atcttttggc acatttgaat atgtttggag aaagttacgg
     2941 ttcccaagta gatcaattac tagaaaattt ttaagaggag ggcgtgtttt tggcaaaaaa
     3001 atataccaaa aagcatgaag tttcatatta tgagtgtgac atcaaccaaa cgatgacatt
     3061 tccttcgatg ttaggagtag ttatcaaaac gtctgaagat caaagcgacc agttgggaag
     3121 aggcagtgaa ttcgtcaata gctttggact tacttgggtc atcacgaatt attccatgga
     3181 gattaatcgt ctccctagag tcggtgaagt aatctcagta acgactcaag ccatggagta
     3241 caataagttt ttctgttatc ggaacttctg gatccatgat gaagatggga aagaattagt
     3301 caaaatagaa tctgttttcg tattgatgga ttttgtgaat cgaaaaatga gcagtgttaa
     3361 tgaagagatc attgctcctt ttgagagtga gaagatcaag aaaatcaagc gtcaggaaaa
     3421 aattgaaaag attgattcgg gcttcatgtt gccatatcgt gttcgttttt atgatatcga
     3481 tagtaatcag catgttaata atgcgatgta ttttaattgg atcattgacg tattaggata
     3541 tgactttttg actacgcatg ttccagaaaa agtaattatt cgatttgata aagaagtaga
     3601 gtacgggaat gagatcgaaa gccattttga acaaatccct atcgaaaatg gtgtcaaaac
     3661 aaaacatgaa atccgaatgc aagaacagct gtattgtgaa gcaaatatta tatggaaaaa
     3721 taaataaaaa agaggttgtg acagaagggg gcaacttcaa gaaataagaa gaaatttacg
     3781 aaaattgttt ctcaaatttt tgtaaatttt cgacttagtt ttcgaagaag ctatttttgt
     3841 cacagcctct ctttttaagt ttagctatta gataatgatg tttagttttg gataaacgaa
     3901 atcaattctt cacccgacaa accatagttt acagcaatca atagttttaa acgtgctttt
     3961 tgactattaa tactgttaca gaaaataatc cccatttttt ctagttcttt tcccccgcct
     4021 tcataatcat aaacaggctc tgcgattcca ttgaaacaac gagaaacaag tactacaggg
     4081 attttttgga caagaagctt ttccaaagca gctaaggctt gtggagggag attccccgca
     4141 cctaaagctt cgattaccaa accgtctact ttcgtatggg cgatggcttc caataagtcc
     4201 ccttgcatcc cagcatatgc tttaacgatc gggatagtcc catctacagc ggaaatgtcc
     4261 agtcgctttg tttctaaaag ttcctgcaag aataaaattc gattcttagt tactaagccg
     4321 atgggaccca atgtaggtgt tcggaaagta gcaacatttg tggtatgggt ctttgtcacg
     4381 tagcgtgcag aatggatctc atcgttcatg accaccaaaa cccccttatc tagcgcttct
     4441 tcacaacttg cgacacgaat cgcactttca aaattataaa ggccgtcact tccaagttca
     4501 ttacttgaac gcattgcccc agtcaaaaca attggtaatt tgttgccaat cgttgtatca
     4561 agaaaaaaag cagtttcttc taatgtatct gtaccgtgtg tgatcaccac tccggatata
     4621 cctgatgcat aagcggacaa gatacgttct tttaatacca acatgtgaga aggcatgatg
     4681 tgtggtgagg gaagattgaa gatatcttca actaataatt ctacatgctt ggggattgtg
     4741 atttctgcat ctaataatgg gtttgccaca tcaggactaa caccgcccgt gagcatgttt
     4801 tctttcatgg cgatcgttcc gccggtgtgt agtacaagta tttttttcat tttacagact
     4861 tccttacgaa taattttgca tagccgttaa atcttattgt atactatata aaagagtttt
     4921 gctatcagtg aagaataacg aatagcctaa cttatcataa aaaagctgac cttattaaaa
     4981 tggaaaagac tcaaccttga cctcctaata caatggagta tctggttgag tttcttttac
     5041 aagaaagcag ccaaggaaat caatcacgaa ggtggccgga aatgatcaga atcggattaa
     5101 catcgtttaa agaacatgac aaattaactg gtaaaaagaa taacactctt tatgaatatg
     5161 cagggtttct acccttagtg gaattagata ctgcctatta tggaattccc cgaaagtcct
     5221 cagttgagaa ttggataagt gaagtacctg aatcatttcg ctttgtagtc aaagtctatc
     5281 aaggaatcag cggtcaagga gactggaagc cttattatca gaccgaagaa gagatgattg
     5341 cgcatttttt agatgttatg tcgccaatgg tagatgctgg aaagatgttt tgctttttag
     5401 tccaattccc ctcatcattc aaatgtacga aagaaaatgt ccagtacttg cgcaaactta
     5461 gaaagtggtt tgagggttat cctgtttcta tagaattgcg ggattattct tggtacagcg
     5521 atgaatttct tgaacgtaca agaaacttta tgtctagagc cgctttttct ttagccatca
     5581 tcgatgagcc acagttgctg aatacaacga ttccttttga tccatttgtc accaatccga
     5641 actttgctct ttttcgattc catggtagga atgcgcaagg atggcaagca aatgataaag
     5701 agtggcgtaa aaaaagaacg ttatatcgtt attcagaaaa agaactgcaa gaactagcac
     5761 atgaagtcaa agtagttgat tctaagacaa aagaggtagg tgtgattttt aataataatt
     5821 ctggtggtga tgcggctgaa aatgcattag cactgcaaaa aatattaaat atcaagccag
     5881 atggactcaa tccaacccaa atggatctgt tttaagggct tattttattc aagaaagggg
     5941 cgaagtctat gatcaaagct attttttttg atattgacgg aacattggtc accaatcgtt
     6001 caaaagcgtt ggaatcaaca aaacaagcaa ttgaatatgc tcggaaaaac ggcattttat
     6061 gcggtgtagc aacggggcgc agcccagtaa agatcaaaga aatcattgat gaattggaat
     6121 tagatatgta tgtcgtgtat aatggtcaac tggtttttac tgcagatcgc acgattatcg
     6181 accacccttt tgaacaaaaa gtattggaac atattgttga atttgcagat gagaaccatc
     6241 gacaaatcgt ttttggtgcg agaaatcggt tagatggatc aacgacgatg ctattaggac
     6301 aatcgatttt tatcaagcga ctagtcagct ttttaccgcg taaattcccg gtacgtctga
     6361 tgaaaaaaat cctccaggtt tttagccctc accgacaaaa ggatcgttat gaaacgttag
     6421 agatattaaa agaaccaatt tatcaatgta tattgctcag tccggagtca gaacagaaaa
     6481 agttagaaca tcgctttccc gagtgtacgt ttcagcgttc aaatacgtat actgtagata
     6541 tcatcccaaa aggtggttca aaattactag gcatccaagc tttcgcaaat gctgtcgaaa
     6601 ttgaaatgga agaaattatg gcattcggcg atcattacaa tgatatcgag atgctgaaag
     6661 gtgtaggaat tggagtggcc atggggaatg ctcagatcga agtaaaacat gctgcagact
     6721 ttgtgactca atcaaatgaa gaagatggga tatacgaagg actgaaacac ttcggtctga
     6781 tttattagtc aatgaaagaa ggaaaaaatc agtatggaag cagagacacc ttttcaaaaa
     6841 gtagaaacat tccacaaaac ttttgatcca agaagaccag agatacccac ggcttttaca
     6901 gaaaatgaag ctcatacacg tgctgcgttc aaaatagaag aacttgttga atttgttgca
     6961 gctacttcac ctaataaaga acaactgcat gaagctgtta tgctgctgca cgaagcatta
     7021 gataaagcag aagaaaaaat acttggtaaa acacagtggg gaagtgatcc gctggttgaa
     7081 caagtagatg cactgacaga tatcctttac tttacttatg gttctttttc attactagga
     7141 atagtgcctg atcgaatatt cgaaatcgtc catcaggcaa atatggggaa attatttcca
     7201 gatggaaaac ctcattatga ccctgtaaca aataaagtgt tgaaacctga aaactggcag
     7261 atggaatatg ctccagaacc taaaatcgcg gcagaaatcc aacgtcagat tcaagaagcg
     7321 attgctaaga agaaatccgc tgatataggc atgtgcacaa atgaaaaaga gtgatcagag
     7381 tttcactatt tttgttatct ttatacgatg gaaaaacaaa agattttcgt ttaagttagt
     7441 gaatgcatga aaatagtatg ctataatcta gaatagatgt cttttgcacg agagacgtat
     7501 tatttggatt tatgccaagc agaacgccat ctgttgcata aaagatgcat actgaaaacg
     7561 gaggaaccat aaatgggaaa taatgttatc atcggaatcg tcattgcaat cattatagtc
     7621 gccattgtcg tctttttggt tagttacttg atgaagaaaa aaaaccaaga tcgattggat
     7681 gccttagaaa aacgcaagga agaattattt gacttgccag tgattgaaga agtcgatgat
     7741 gttaaaaaaa tgcatctggt tgggcaaagc caaaatacct ttcgtgaatg gagtcaaaaa
     7801 tggaatgaca tatctacttc ctcgttcgct gaactagaaa gtcaaatttt cgaagtggaa
     7861 aacctcaatg aaagttttcg gttcttaaaa ggaaaaaaag cagttgttga agcagaagct
     7921 acaatggacc aaatggagaa acaagtgacg gaaatccgtg aaggtctaaa ggaattgcgg
     7981 gaaacggaag aacgcaactc actagctgtt cagcaggcac ttgacgtcta tgaagaactg
     8041 aaagaaaaag tcagagaaga cgagcatgaa tacggaccag ctctttttga attgcaaaaa
     8101 cagatcaaag tgatcgaaaa agaatttacg cagtttgtga ctttaaacac ttctggagac
     8161 cctgttgaag cccgcgaggt tttggataaa gcagaaaaac atacgtatga agtggaagct
     8221 ctgatgaaaa aaattccacc gctgtatgag gagctccata ccactttccc tgaacaactt
     8281 gaagaaatca gtgatactta cgagaaattg atggaagaac aatatgtatt cccagaagaa
     8341 gatcttgctg aagatatcgc aaaagtaagt cgaagaattg aaaattcatt agccaatctt
     8401 gaaaaaacag aagttgaaac ggtcgaattt gaaaaccgtg aaacagctga tttgattgat
     8461 tcgttatatg atatcttaga acgggaaatg gaagctcaga gatatgtaaa aactaaccaa
     8521 tcaacgattg cagagtatat caaacataca acaaagaata accgtcaatt attgattgag
     8581 ctggatcaca catctcaaag ctatacattg aaccacaatg aaattggccg tgtacgaggt
     8641 ttccaaaccg aagtggaaga aatggaacgt caaaatgaac agatgattcc acagatccgt
     8701 caacacgaaa ttccttattc agaagtgcgc acgttctata aaacagtctt caaagtctta
     8761 gaagatatcg aaaagcaaca agtagagatc gacgactcat tacatgaatt gagaaaaggc
     8821 gaaaaagaag cgcaagaaaa gatcgataca ttcgaattca aattgcgcag tttgaaacgt
     8881 tttgtagaaa aacaacgttt gcctggcttg ccgaatgatt acctagaatt cttttttgtt
     8941 gctactgacc gtattgaaga actaagtgtt gtcttgaata aaattcgagt aaacatggaa
     9001 gaggtcaatc gtttagttgc tctatgtgaa gaagatctag aattattaga taagaagaca
     9061 catgatttag tagatgcagc agcattaacg gagcaaatgc tccaatatgc aaatcgttat
     9121 cgtcatacac acgaagaagt gagagaagca attgataaaa gctactattt attcaataaa
     9181 gaatatcact atcaagaagc attagacgaa atcggtacag cattagagcg agtagaacct
     9241 ggtgctttca aacgcatcga agatttttat tttaatcatc cagacttagt ataaagcaaa
     9301 aaagttagta aaccagcaag agcaagacgg attattgtct tgttcttgtc tttttttgta
     9361 tatttgaaaa ttgaaacaag tgaaaatttc acctgctctt gaaagcacct tggacaaccg
     9421 ttataataga aaagaatttc aaaaaagagg ggtttcttat gatatatttt gataacagtg
     9481 caacaacccc aatctttccg caaagcttag atgcatatgt aaaaaccagt cagcggatta
     9541 ttgggaatcc atcaagcttg catgatttag gcaatcaagc taaccggttg ttgcagcaag
     9601 caagaaagca gatcgctgat ttgatccatg tagaaccaga agaaatctat tttacttcag
     9661 gcggaacaga aggagataac tgggtattaa aaggaacgat gatcgaaaaa agagaatatg
     9721 ggaatcatat gatcatttca ggagtcgaac atccggccgt cagcgagaca gcagaacaat
     9781 taaaagaatt aggaatcgaa gtaagtatcg ccccagtgga taaacgcgga tttgtacgtg
     9841 tcgacgaatt gaaagaatta ataagaaaag agacagtatt agtctctgtt atggctgtga
     9901 ataatgaagt aggatcgatt cagcccatcc aggaaatcag tgatcttttg gatgattttc
     9961 ctaaaattca tttccatgta gatgctgttc aggcgattgg aaaagtacca ttctcgcaat
    10021 ggttgacaga aagagttgat tttgcaacat tttcagctca taaattccat ggcccacggg
    10081 gaactggttt catttattgg aaaaagggtc gtcgtttagc accattactg acaggtggag
    10141 ggcaagaaag aaatcagcga agtgggacag aaaatgttcc aggtattgtg gctatggtta
    10201 aagctttacg tttatcatta gagataaagg aacaaaaacc tgagcagaca caacgcttaa
    10261 aagtagctct aatcaatgcg ttgaagacgt atgagaaagt gacgattttt tcagaaggaa
    10321 ctgactatgc accgcatatt ttatgttttg ctctaaaagg aattcgcggc gaagttctcg
    10381 tccatgcctt agaagaaaaa caaatatttg tttctactac tagtgcctgc tcctcacgta
    10441 aacatatggc aagcagtaca ttgcacgcaa tgcatgtacc aaatgatctg gctacatctg
    10501 ctgttcgaat cagcttagat gaaaacaatt cgcttgcaga agtcgagcaa tttatgatta
    10561 ttttcaagca gctttataag aaattttctg caatcaatta aaagaggagt gttcttgtga
    10621 aatacagtga aattatggtc cgttatgggg aactttcgac aaaaggaaag aatcgaaaaa
    10681 gctttatcat gcaactagca caaaatgtca gacaagcttt gaaagacttt ccagaaatca
    10741 aaatccatgc tgatcgggac cggatgcatc ttttattgaa tggcgcagac gggcagctag
    10801 ttattccaaa actagcaaaa atatttggga tccaaaattt ctctccaagt attcgtgtag
    10861 aaaaagatgt cgaagttttg aaacaagctg ttcaagacat catgaaagaa atttatactg
    10921 ggaaagaaac atttaaaatt atcgctaaaa gaagcgatca ccaatttgaa ttgacaagta
    10981 atgaattgaa tcaaacatta ggtaatgctg tttttgatat tttcccgcat atccaagttc
    11041 aaatgcgtca accagatatt ccattacgtg tagagattcg gcgtgatggc gcttatctat
    11101 cgtatgaaac gatcaaggga gctggaggat tgcccgtagg aacaagcgga aaaggaatgc
    11161 ttatgctttc tggggggatt gattctcctg tagcagggta ctttgccatg aagcggggag
    11221 tggaaattga agctgttcat tttgctagtc cgccgtatac aagtgaacaa gcactgcaaa
    11281 aagcaaaaga tctaacagcc aaactagcac cttatgtggg aacgatccat tttatcgaag
    11341 tgccatttac cgagattcaa gaagaaatca aaaagtcagt gccacaagga tattggatga
    11401 caattactcg tcgaatgatg ttgcgtttga ccgatgaaat tcgccgtatt cgtcatggtt
    11461 tagtcatttt gaatggtgaa tcattaggtc aagtggcttc acaaactttg caaagtatgg
    11521 tggctatcaa tgaagtaacg aatacgccaa tcattcggcc tgtagcgaca atggataaac
    11581 ttgaaatcat tgaagtagca gaacagatcg atacatttaa tctttctatc cagccttttg
    11641 aagattgctg tacgattttt gctcctccac agccaaaaac acgccctcaa ctggaaaagg
    11701 tccatcaata tgaagagcgt ttagcaatag atgaaatgat ccaacgagca ctagctggct
    11761 tgaagatgga agagatacaa gcagaatcgt ctaatgaaaa aactgaagaa ttttcagaat
    11821 tgctataaga ggttatgaaa atagtgtttt gaccagagta ttagagaaac aaaacgaaaa
    11881 aatagctcca tgtattttac cgtttttgaa ctaatgtcga agattagctg attgaatacc
    11941 atttatcaag aagttatgga aaagccggtt cttttttact aactgaaaaa taaaatttta
    12001 tttagagatc aagctacagt tgataaatga tataaaaaag agaatttccc atgaaatagc
    12061 gaggttgtga cagaagtggg cagcttcaag aaataagaag gaatttacga aaattgcttt
    12121 tcaaattttt gtgaaatttc ggcttatttt tcgaagaagt tacttctgga acaccgtgta
//
LOCUS       DADQCX010000080        12086 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.081, whole genome shotgun sequence.
ACCESSION   DADQCX010000080 DADQCX010000000
VERSION     DADQCX010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.081"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            17..2035
                     /locus_tag="J8R83_002125"
     CDS             17..2035
                     /locus_tag="J8R83_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9575244.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            2462..4876
                     /locus_tag="J8R83_002126"
     CDS             2462..4876
                     /locus_tag="J8R83_002126"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAZ9575245.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            5224..6777
                     /locus_tag="J8R83_002127"
     CDS             5224..6777
                     /locus_tag="J8R83_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAZ9575246.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(7158..8942)
                     /locus_tag="J8R83_002128"
     CDS             complement(7158..8942)
                     /locus_tag="J8R83_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575247.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(8957..10678)
                     /locus_tag="J8R83_002129"
     CDS             complement(8957..10678)
                     /locus_tag="J8R83_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575248.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            10778..11539
                     /locus_tag="J8R83_002130"
     CDS             10778..11539
                     /locus_tag="J8R83_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9575249.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         3961 a         2184 c         2440 g         3501 t
ORIGIN      
        1 agttggagga tagaagatgg aaaacattgc aagaaaagaa cggagacgtt tagaacagac
       61 caaacgtttt cgaaaagcaa aacgaggggc agcaatcgtg ggaactgcga tggtaggctg
      121 ttctgtcgct gccccattag tacagccggt tcctgttcaa gcggatgaaa cacctgttca
      181 gttcggcgca agaatcaata cagcggcatt tatcacagaa attgctactt atgctcaacc
      241 aatcgctcaa gccaacgatc tatatgcatc agtgatgatc gcacaagcag ttgtagaaag
      301 cggttggggc agtagtgcgt tatctcaagc accttattat aatctttttg ggataaaagg
      361 cagctatcaa ggacaaaccg tctacatgga tacgcttgaa tttttaaata atcaatgggt
      421 aaataaaaag gagcctttcc gacaatatcc ttcttttgct gaatctttca atgacaatgc
      481 ctatgtactt agaaatactt catttggcaa cggttattac tatgccggta cttggaagag
      541 caacacgaaa tcctatacag atgcgacagc ttgtttgaca gggcgttatg cgactgatcc
      601 tggttacgca ggcaaattaa ataatatcat cgcaacttac ggattgaccc aatatgatac
      661 accagctagc ggaaacgcag gcggtggagc gactacaggt ggcaataata ctggaagtgc
      721 aggtagtact ggcggttcaa gcaattctgg taatacaaac tcaggttcag caacttcgac
      781 cacttatact gtccaatctg gtgattctgt ttggggaatc tcaaataaat tcggtatcac
      841 aatggatcaa ttgatccaat ggaacaacat ccaaaacaat ttcatttatc caggacaaaa
      901 actgacaatc aaaggtagcc aggaaaatgg ctcttcgacg aataattccg gtaacaatac
      961 caattcttca ggaaatgctg gtacatcaaa cggaggacaa acaactggtg cgaaatacac
     1021 tgttcaatct ggtgattctg tttggaagat ctcaaatgat cacggaatta cgatggctca
     1081 attgattgaa tggaacaata tcaagaacaa tttcgtttat ccaggacaac agctaatcgt
     1141 atcaaatggc ggttcttcta atgctggagc aaatactggc tcaaatactg ggaatacaag
     1201 tggctctagt tcgtccagct caagttcttc taatacagct tcaggaacga aatatacagt
     1261 taaagccgga gactctgttt ggagcgtctc aaataaatac ggaattacga tggctcagct
     1321 aatccaatgg aacaatatcc aaaataactt tatctaccca ggacaacaac tgactgtttc
     1381 aaacagtgga tcaacaaaca gcacgtcagg taatacaggt tcgtcaacca atacaaataa
     1441 cagcagttca gttaatactg gcagcagttc gtctcaaggc acttataccg tgaaagcagg
     1501 tgaatctgtt tggagcgtgg caaataaaaa cggcatcacg atggatcagt taatcgaatg
     1561 gaataatatc aaaaacaact tcatttatcc aggacagcaa ttgatcgtta aaggtggaac
     1621 ttcggcaaat acaaatacag gttcaactac ttctgcagcg aaaccaaata caccgaatac
     1681 gtctgctacg acaagtacat catccactgg taatacgatg tataccgtga aagcgggcga
     1741 gtcagtttgg agcgtagcga acaaacatca tatcacgatg gatcagttaa tcgaatggaa
     1801 taatatcaaa aataatttca tctatccagg acagcaagtg attgtgaaga aaggttcatc
     1861 tcaatcaaca aaccaacaat cagttactgg ttcgaaaacc tatactgtga aatctggaga
     1921 atctgtttgg agtgttgctg acagtcatgg aattacaatg gctcaactaa tcgaatggaa
     1981 caatattaag aacaacttta tttatccagg tcaaacgttg attgtagcta aataaaatag
     2041 ctgttcgaag aaataacgat tgaattccac aaaaatattt gttactataa ggctacttaa
     2101 atatgacaac acttgaaaag gaagtagtaa aaagactgaa gtttcagaga gcgcatggct
     2161 ggtgagaatg tgcacggatg cttttgaact cgcctttgag ttgcccttgc tgaatacccg
     2221 agtaagcaag cggcggtgac ggccgttaca acgttcgagg ccttttcact aaggtaaaat
     2281 taggtggtac cgcgtagatt acgtcctata aaaagagcaa tctttttata ggattttttt
     2341 atttcttttg tgaagtttga gaaaacaaag caaaaggaaa taaaaataaa cagattctgc
     2401 cggttttttc gttatattta taatagaaac aagtgttttc aatagaacag gaggacagca
     2461 aatgagttac aatcataaag aaattgagaa aaaatggcaa aaatactggg caaaaacgaa
     2521 tactttcaac acccatgatg atcctgaaaa gccaaaattt tacgcactgg atatgtttcc
     2581 ctatccatcc ggtcaagggc tacatgtagg gcatcctgaa ggttatacgg caacggatat
     2641 cctttcacgt gtgaaaagaa gtcaaggata caacgtgctg catccaatgg ggtgggatgc
     2701 attcggtctg cctgctgaac aatatgcgct agatacagga aacgatccag ctgagtttac
     2761 ccaaaaaaat atcgaaacat tccgacgcca aatcaattct ttaggattta gttatgactg
     2821 gaatcgcgaa gtgaatacaa ctgatccgga gtattataaa tggacacaat ggatctttac
     2881 gaagctttat gaaaaaggtc tagcttatga agcagaagta gcggtaaact gggtacctga
     2941 attaggaaca gttatttcaa atgaagaagt gatcgatggg aaaagtgaac gtggtggcta
     3001 tgatgtagtc agaaaaccaa tgcgccaatg gatgctgaaa atcactgctt atgctgatcg
     3061 cttattggat gatctagaat tagttgattg gccagaaagc attaaagaaa tgcaaagaaa
     3121 ttggatcggt cgttcagtag gagcaaatat tgaatttaaa gtggctggta cggataaatc
     3181 ctataccgta tttacgacac gaccagatac tctattcggt gcaacttact cggttcttgc
     3241 acctgaacta gatcttgtta gagaaattac gacccctgaa caaaaagctg ctgtagaagc
     3301 ttatatcgaa gagacagcta aaaaatcaga tctaaagaga acggatcttg caaaagaaaa
     3361 aacaggagta tttactggtg cttatgcaat caatccagtt aatggcaagg aaatcccaat
     3421 ctggatcgcc gattatgtat tatcttcata cggcacagga gccatcatgg ctgttccagc
     3481 acatgatgaa cgtgactttg aattcgctca aactttcgga ctagaaattc ttccagttat
     3541 cgaaggtgga gatgttgaaa aagctgctta cacagaagat ggtacgcaca tcaactctga
     3601 atttctagac ggcatgaaca aacaagaagc aatcgataaa atgaatgaat ggctagaaga
     3661 aaatggcgta gggaaaaaag aagtcagcta tcgcttacgt gactggctat tctcccgtca
     3721 acgttactgg ggtgaaccaa tcccaatcat ccattgggag gacggaacag tcacagctgt
     3781 cccagaagaa gagctaccat tacggttgcc taagacaaaa aacatcaagc caagcggtac
     3841 tggagaatct ccattagcaa atatcgagga gtgggtcaat gtcgttgatc ctgtaacagg
     3901 taaaaaaggc cgtcgcgaaa cgaatacaat gccacaatgg gcaggaagct catggtatta
     3961 cctgcgttat atcgaccctc ataacaaaaa agaactagca gattatgaaa agttgaagcg
     4021 ttggctacca gttgacatct acattggtgg agcagaacat gcggtacttc atttactata
     4081 tgcacgattc tggcataaat tcttatacga tatcggtgtt gttcctacaa aagaaccatt
     4141 ccaaaaacta tacaatcaag gaatgatctt aggcgaaaac aacgaaaaaa tgtcaaaatc
     4201 tcgtggtaat gtagtcaatc ctgatgatgt ggtcgaaact tacggtgcag atacactgcg
     4261 catgtacgaa atgttcatgg ggccattaga tgcttcgatt gcttggagcg aaaatggctt
     4321 agaaggaagc cgtaaattct tggatcgtgt atggcgtttg atcgttgatg agaacaataa
     4381 aatgcgtgac cgtatcacta cattgaatga tggcaagctt gataaagtgt atcatcaaac
     4441 agtgaaaaaa gtgacagaag actatgaaaa tcttcatttc aatacagcaa tctcccaatt
     4501 gatggtcttt atcaatgaag cctataaagt ggacgctctg ccttatgaat atatcgaagg
     4561 atttgttcaa ctactcgcac cgattgctcc tcacatgggt gaagaactat gggcaatcct
     4621 tggaaatgat ggtggtattt cttacgcacc atggccaaca tacgatgaag cagcacttgt
     4681 tgaagacgaa gtagaagttg ttttccaagt aaacggtaaa gttcgtgcga aaagcaatgt
     4741 tccccgagac ttaggaaaag atgagctaga aaaagcagca ttagccaatg aaatagtgca
     4801 agaatatatt gaaggcaaaa cagtcagaaa agttattgcg gtaccaaaca agttagtcaa
     4861 tatcgttgct aattaattgg ctctttgtca ataaggactg atgagttgtg caaaatcaaa
     4921 tctgggccag aatgaacttc attctgtctc agattttttg ttatttcaaa ttgattaatt
     4981 gattgatcaa aaaggttttg attttcatgt tctcaaacac gttcaatgtc tttttcttct
     5041 gaatggtctt gtaagagatc tctgtaatca tcaaattttt gtctattaat cttagtattt
     5101 tttgatgtat aaactacctg aaattgagag tacataccaa attcataaat tttttattag
     5161 tgggactagt gattgtatgg attttgacgc ataatgaatg aagtatgaga aaaggagaga
     5221 caaatggatc aagaactatt tattatcgaa gtattatcag ctaaacaaaa aattatcgag
     5281 aaagcgaaaa aaagagcgaa aagaataatg ttcaagcttt taagcttagt atttttctct
     5341 ggtttgcttt ttttcggagc tgtatcgttc ctatatcgcc atatgagtgc agtagtccgt
     5401 tcagctgaag ggatgcaaaa attaaataat ttgtatcact tttcgtgggg agttggcgga
     5461 ataacaattg ttgtgcttat tgtttttctt ctacttattt ggctccgtta ccatcaattg
     5521 tcgcgtcatt tcgatcaatg gcttagtcaa agagcacaac agtttttaca taataaacca
     5581 acttctcaag atgatgacta tctttatttt gagaagactt cgacgagtca agcttttcgg
     5641 atacaaaaaa gtgattgcca gttattgctg agatcacttg atgatttacc tatctactta
     5701 ggcgaaagca aatcaaaatt cggaatgaac acattccata tttttttact agaaaacgaa
     5761 cccagatggg aaaaaagcca gtcttcgcct ggtggatacc tgacaactaa gatgagtaca
     5821 ttagtcactg gttttttcct cattctttta gctggaacaa tctattatgg gagatacact
     5881 cagccaaaaa tgtcttctca tataaatgct gcttctcaca tgacaatgaa ctcaactaac
     5941 gatacgcata tacaaaagac aaatgaaggg ttgttagctg atcctaagca aaaggtaaat
     6001 ttgacaacac aaaagataaa tgatctcaaa cttgatacag agacgcactc tctctatatg
     6061 acaacagata gtggtgctaa ttgggtattt gtgccgattg attcgcaatg gttgcgtttt
     6121 ggcgaataca ccctgacaac ggggctgatt cctgaaggtt attggatgga caacacatat
     6181 gatatttccg ccgatttctc atggtttatc tattcttctg gggatgatgt acgtctgctg
     6241 acttcaagag ataatggtaa aacatggcaa acgtctatta tcacccaatc agttcagccg
     6301 atacgttatc gaaaagcggt attttatggc aacgatggtc tatttatctg tacatcagcc
     6361 agtgggatgt ctgcagaaac tttgtacatt tacactacta tggatggcgg aatcacttgg
     6421 ataaaaagtg gaagtacaat gatcaatcag ccagtacaaa atgtcagctt cgttacaact
     6481 tctttaggtt ttgtttcgac acgtgaaagt ttgttttata caaacaacgg aggacgctca
     6541 ttcaaagaat cagttctgtc gattccggaa aactatcaga caggggggat agatcttttt
     6601 caatcaccaa atgaagttac tcaaataagc gcgaatacgt tagagacaaa attttatttg
     6661 ttgaaaaaag gaccaatcga tgcagggaaa atgtttgcct gcctcttccg ttcaactgat
     6721 aacggggaaa catggcaatt cgttcagcaa ctatcgcaag tagaacaagg agattaaaga
     6781 agagagattg tgagcctgac gttcagcacc gagtcacaag aaacaaattc aaaaaacagc
     6841 ttctcatatt tgttgaatag tgtaactcgt gattcggagt tgacaagagc aacaagaagc
     6901 gattttgaag tatagcttct cgtattttac aagatcgtgt cttattgccg ataggttgtc
     6961 tcttgaacac cgtttattcg taaaaaggga ttgtgacaag tcttttgtca ctacttaccg
     7021 aacgaaactg aaggagctat ccaaaaagta tcattagtat tattctttgt gtttctagtg
     7081 gcaccactag tacatttaaa aaagctatcg atcatggact aatcatacat gatcgatagc
     7141 tttttagata atgtttgtta cgctatctga aattgactat tataaagact ggcataaagc
     7201 gttggtgatt ggagtagttc agaatgtgtt cctttttcga cgatatcgcc attcttcatt
     7261 acaaggatca tgtctgcatt ttcaatcgtt gacaaacggt gtgcaatcac aaaacttgtc
     7321 ctatcttttg tcacagcttc cattgcttgc tgaatcaatg cttctgttcg tgtatctacg
     7381 ctagaagttg cttcatctaa aataacgaca ggaggattcg ctagaatgac tcgagcaatt
     7441 gtcaataatt gttgctgtcc ttgagataac gtgccgtttt cgctagaaat gatcgtatca
     7501 tatccgtctg gcagtgttcg aataaagtga tcacattgtg cgatttcagc cgcttcgata
     7561 atttgttctc ttgtggcatc cattttcccg taggcgatat tatcagctac cgttccttca
     7621 aacagccagg tattttgtaa aaccatccca aaagaacgac gtagttctcc acgtgaaagc
     7681 ttggtaatat caagaccgtc gaattcgatc tttcctttat tcagttcata aaaacgcatc
     7741 agcagattga ctaaagtcgt ttttcctgca ccagttggac caacgatcgc taccgtttgt
     7801 tttggcttta ctgaaaaatc gacttgattc atcaatattt tatctgatgt gtaaccaaac
     7861 tgtacatttt tgaaagctat ttttcctttc ggttgttcta aaagtcttgc atctggaagg
     7921 tctggaattt catctgtttc atctaatatc tcaaatatcc tatcgattgc tgccattgcg
     7981 gattggatcg agttgatcac ataagaagcg gtagaaattg gttcagaaat ctgattgatg
     8041 tactgaagat aagcttgtaa gaagccgatc gtcacaccac ctgatagaac aagcatagca
     8101 ccgaataccg cacttatgat gaaggcgagt tgattaatga aacgaatggc cggatagata
     8161 gcacagttca taaattgagc acgtttaaaa gcgttgtatt gctttttatt tacttcgtgt
     8221 atagcagctt ctgcatgagc ttgctgattg aatgttttga ccactagatt accagctaag
     8281 atttcttcca ttcgattatt taaaacaccc agttcatact gattctgttc agaaatctgt
     8341 ttgtttttgt tcgcaatctt agttgtaaca attgaactgc caacgatcag caataagacg
     8401 agcaaagtaa gcttgctttc gatataaaac agcatcagac cagcagcagc tattgttacg
     8461 acagaagtaa aaaattgatt gatacctgtc aataacactt gagaaagttg attgagaccg
     8521 gtagttgtcc gactaatgat gtcacctact tgatgattgt caaaaaacga catcggtaat
     8581 gttttgaatt tttttgtgat ttcttttcgc accctcaatg tgatcttttc gcttaacgct
     8641 gccattgtcc gttcctgaat aaatgaagtg atgctgctta agactgaaca gccgatcagc
     8701 aataagacag ggaacaacaa tgcttgtttg atatcactga aagaaagctg tccaatacct
     8761 gtttttctta tttctgataa gagatcatcg atcccgattc ccatgatcaa gggcatggct
     8821 acgactaata ggttcccgaa taaactgcat agaaacaatc cgtaaaaata tttatgttca
     8881 ggtttgatca ttttccaaaa acgtatcaaa gcacgcgtgt tcaacgtttt tttcttttcc
     8941 atcgtatccc ttctttctat attccttgtg attttgcaaa ctcctgataa gtttggcaat
     9001 tagacagtag ttcttcatga gtaccttgtc caacgatttt tccttcatct aaaacaatga
     9061 tgttatctgc ttgttggatt gtactgaggc gttgagcaac aatcacgaga gttttctccg
     9121 acatgtgttt atgaagggct gctcttaatg ctgcatctgt tttatagtct aaagcggaga
     9181 aactatcatc gaatacatag atctctgctg gtttgatcaa cgctcgagca atacatatcc
     9241 gctgtttctg gccccctgaa taattagaac cgccttgagc aacaaagctg tccaatccgt
     9301 caggaagggt gtccactagt tcttctaatt gagcgatctt gatcgcttta gacaactctt
     9361 ctgttgaggc atattcattt cccatctgca agttgcttaa aattgtcccg ctgaataaga
     9421 aagccttctg agggacataa ctgatgtggg agcggatctg ttcttgagtc atttgagtaa
     9481 gaggaatacc accaagggtt acttttccta tcgtagggtc actaagtctc aagagaagtt
     9541 tcgccaaact actttttcca gatccggtcc cgccaacgat cgctgttgtt tttcctttag
     9601 gtattgtgaa atcaatatct tctagaactg gatcagagat ttcagtatat ttaaatgtga
     9661 catgttcaaa agcagctgca tttgtctgat caaaggttgg ttcagctact gttttgatcg
     9721 tctcttcctc aatttcgatc tctgcttgca gtatttcttc tatccgtcgt aatgaggcaa
     9781 acgatttagg gataatgacc aataccatag ctgcgatcat caagtaagca agtgtcagca
     9841 tagagtattc gactacagca gtcacgacac cgatttgtaa tgctccttct gctacaagat
     9901 ttccgccaaa ccacaaaata gaagcataaa cgattcccat gagcaaaaaa gcaattggag
     9961 tgacccaagc aaatattcgg ttcactttga tcatttgatt agcatagtca gcaaagctct
    10021 tattcgttcg cttttcttca tatgattgat tatcaaaggc acggatcata ttaatcccag
    10081 taaagaattc tctcaatgtg atggtgatcc gatccatttt tggctggata ctcaaagata
    10141 aaggtgcccc tcgtttcatc agtcgataaa caatccatac ataaaaaaca acagagatca
    10201 atgtaaccca tgttagtaat agagaataac gaaacatcat gagaatggtg aaaacgcaaa
    10261 taaccggtgc tggtaagatc atttggcaaa ataaaacaat catttgctgg acattatcga
    10321 catcattcgt cattcttgtc aaaagagatc cagaactaaa acgactgata tccttcattg
    10381 acagctgttg gaatttacgg aaatatttct cccgcgtttg gaatccaaac ctagcggaag
    10441 ccaatgctga aaagtaacta gaggcaactg cagcgattgt tcctagaaac gctacaagca
    10501 gcatttcaac tccaattttt tttataactg aggcttcgcc acttgctata cctgtgtcga
    10561 tcagctttgc tactaatttt ggtacaccta atgtaccggc gatttctaaa cagatcatca
    10621 caaaggtaag gagagcgagt cctttgtttt tctgtaagaa tgtttttaag atagacatat
    10681 tattcctcct tttttcctga tacttttcga ttctatacct tcaagtaact tgaaggtcaa
    10741 tagaaaaaag aataaactga aaaagaggtg agaaaaaatg aaaaaaatgt atacgattgg
    10801 ccaagtatcg gaactatttg atttgccaaa atcaacgatc cgctattggg atgaacaagg
    10861 attaatccgt tcaagtagac aagaagagaa tgattatcga ttgtttgata tcgatgatat
    10921 ttttatgctt tatgatatcg ttttttatag aaaattagat ataccgatca aacagatgaa
    10981 gaatttatat ggaaaaacat tgacggagtt atatgagaca cttgatgaaa cagaaagaag
    11041 aatccataaa gaactggtgg tgatgaaaca aaaacaaaaa gagataaggg agcaaaaaaa
    11101 acagttgaaa ttgatgatcg atacaaacga ggaagaattt cctgtagaag agatcccttt
    11161 tgactgtatg atctcaacgg agtttgaaga tattgtggaa atcaaaaaat ttctacctaa
    11221 ctattcaagc tttgggatga tgagtatgcc agcttccagt tcacagacga tgtatggatt
    11281 ttttatcgac cctagtgaag tacatttatt tactcaagac gtgatttggg agaaaaaaga
    11341 tacggctgtt tatcgtcgat tcttattgaa atccgagatg aaccatgcgg aacgtaataa
    11401 tattttagaa atcagagaaa gaatgtatga aaaaggatgg aaaacaggag aagtgatcgg
    11461 ccagtatcta ttgacgaata cggatgaaaa caatatcaga actgaatatt atcatgcatg
    11521 gatagaaatg aaaaaatagg aaatatgtgt ttaagataac tcgaaaatga tggttgtttt
    11581 agttataaag aaaaattttc tggttcgatt acgggtttaa tgtgggggat tattagtcgt
    11641 ggatagatag aattttagtt ttttagagga aatatgtctt taaaaatgga atggttgcaa
    11701 ttcttagcga tatatacgat gtaattgtcc tcttaaaaaa gtatggaaaa ataattgtat
    11761 tgggtgttat gtataattca tggtgaactg agactaatga gaagaaaaat tcatattgtt
    11821 atgagtgaga ttgtatcaga tgagaatgat aaattaaata ggtgcataaa agcattacac
    11881 ttaaaataca ttgttgctta cattattaca atatgttaat aaggcaaaaa taaatagatg
    11941 gattgaataa acatattttt taatcaaata gtccctactg tgactttcct cagctatcgg
    12001 tgatactacc gatagcattt ttttgcttat aaaataatta taagtattta gagatttttc
    12061 ttctaacatt cttcaaacaa gaaaaa
//
LOCUS       DADQCX010000081        11918 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.082, whole genome shotgun sequence.
ACCESSION   DADQCX010000081 DADQCX010000000
VERSION     DADQCX010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.082"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(104..310)
                     /locus_tag="J8R83_002131"
     CDS             complement(104..310)
                     /locus_tag="J8R83_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575250.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(326..940)
                     /locus_tag="J8R83_002132"
     CDS             complement(326..940)
                     /locus_tag="J8R83_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAZ9575251.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(1087..1770)
                     /locus_tag="J8R83_002133"
     CDS             complement(1087..1770)
                     /locus_tag="J8R83_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAZ9575252.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1879..2337)
                     /locus_tag="J8R83_002134"
     CDS             complement(1879..2337)
                     /locus_tag="J8R83_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAZ9575253.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2421..4184)
                     /locus_tag="J8R83_002135"
     CDS             complement(2421..4184)
                     /locus_tag="J8R83_002135"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAZ9575254.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4405..5865)
                     /locus_tag="J8R83_002136"
     CDS             complement(4405..5865)
                     /locus_tag="J8R83_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575255.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(6073..6999)
                     /gene="glsA"
                     /locus_tag="J8R83_002137"
     CDS             complement(6073..6999)
                     /gene="glsA"
                     /locus_tag="J8R83_002137"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAZ9575256.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(7022..8449)
                     /locus_tag="J8R83_002138"
     CDS             complement(7022..8449)
                     /locus_tag="J8R83_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9575257.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8480..9694)
                     /locus_tag="J8R83_002139"
     CDS             complement(8480..9694)
                     /locus_tag="J8R83_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAZ9575258.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(10035..10277)
                     /locus_tag="J8R83_002140"
     CDS             complement(10035..10277)
                     /locus_tag="J8R83_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9575259.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(10309..10866)
                     /locus_tag="J8R83_002141"
     CDS             complement(10309..10866)
                     /locus_tag="J8R83_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9575260.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(10879..11067)
                     /locus_tag="J8R83_002142"
     CDS             complement(10879..11067)
                     /locus_tag="J8R83_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAZ9575261.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(11080..11646)
                     /gene="amaP"
                     /locus_tag="J8R83_002143"
     CDS             complement(11080..11646)
                     /gene="amaP"
                     /locus_tag="J8R83_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAZ9575262.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         3491 a         2460 c         1948 g         4019 t
ORIGIN      
        1 aaagaatccc gttgcaaatt ctttcagttg caccaggatt ctttgataat tttttagttt
       61 tatgtgtttt tttatatgtt ttttcacttt tcggaataaa tatttatttg ttaaagtaat
      121 taaacaatcc gctaatcgtt tgatctggca tttctatttc cttaccatct aaagtaacag
      181 tagtaacgac aaaatggtct tgcaatggcg gaacttctaa gtactgccct tgcagaaaat
      241 cattcactgt ttcatattct tttttcattt cttttgaatc tgtcgatggt ttatagctta
      301 tttttaacat aactagtgct cctttttatt cgggacgtgc aatcgtgaaa atttctccta
      361 ttgctgcata atcatttcct gccaaacggc ttacagcatt caattttctt ggatcgatcc
      421 ttcctgtctt atcatcatag actgtttcat ttaaatgata tttctgtact tctagcaaaa
      481 ataaatcagc tgttacttta tttttattcc gtatctcgac atgttcatat aaggatgttt
      541 caaaacgaac ttttgcttct gtcaatgctg gtactgaaat gattactgaa tcagttaaag
      601 tcaagtcagt caggtacagt tcgctttcct cattaggcag attggctgct gttttattta
      661 cttcttctac gttgtcctca tcaaggatat ggataacagc ttctcttgtc tcaagaatat
      721 tctttgctgt gtcttttact gcatcttgtt ttctctggat cgccaaggat aagatgggtc
      781 gattcgaact gacgatattg aagtaactga agggtgcgat attcactata tcttttgctg
      841 atttagtcgt tactactgct actggtctag ggatgactga accaatcagc aacttgtaat
      901 tttcacgttc tgtcaattct gaaggactcc gttcaaacat ggtttcgcct tctttctata
      961 aaattcgtta aaaagcagat cttgaagaca aaatgaaaag taatgctttt ttcatcttct
     1021 tagaatctgc tttaaactat ctatcaattt ttcttttttg tcaagaatct gtgccgtgcg
     1081 tgttttttag ttatttgctt tacttgcggc ttcgacatat cttttagtga tcaattgcgg
     1141 acgggtgata atagatccaa ctacgactga aaaagcacct aattcatatg ctttctctac
     1201 ttgttcagga gagtcagtat gtccttccat aattactggg atatcgactt gttctatgat
     1261 ttgattcaat aaatcaaaat caggtgtctg cgtctttcgt gaatattctg tatagcctgc
     1321 taaagtcgta gacaaaagat caaaaccatc ttcttgcgct tgaagcgctt cctcaaaagt
     1381 cgaaatatct gccatagcta accgaccgtg ttcgtgaatc atttggacaa gttcagcagt
     1441 tgttttttct gtcggacgtt tacgagaagt tgcatccagt gcaatgattt ctgcttgcgt
     1501 ctccaaaagt tcttccactt ctttttctgt cgcagtaata aacacttctg acccatcgta
     1561 atctcttttg ataatcccta ttaccggtaa atcaacgatt cgcttgattt cattgatatc
     1621 ttctgtcgta tttgctcgaa taccaactgc tccgccttct tttgcagcca aagccattct
     1681 ccccataata aaagaactgt gtagcggctc gttttccaaa gcttgacaag aaacgacgac
     1741 tccgcctttg atttgttcca gtgtatccac aatatctcct ccagtaatgt tatataaaaa
     1801 tacagcttca tataaaaatg taaccctttt ctattcagga gacaataatg agctatttct
     1861 ttcagcagac ctttcttact aaaagaaaat tacttcaaat tcttcgtata cgaccagctt
     1921 ctcttctgta aattctatgt tcaacgcttc tttataagca tgtttaaaaa actcagcatg
     1981 gactttccgc caataagcta atgtccgatc cccttctcct tctttccaag catgctcttt
     2041 cgtgacttca ctaaaaggca agatggtcac atttatattt ttgatgatac aaactggttc
     2101 attttttcca ttcaggacca cgtctaattg accaactttt ggtaaaggct cattctcttg
     2161 tttatacaga tcgtaaccac ttgatgtacc agtctttatc ttttttacaa ctagttcgct
     2221 caactcgtct gccatttttt ctgtatcccc aaatgaaaag aaacctaatt tttctgattg
     2281 ataactagga tatttttctt ggaacttttt gacatattct tctacttgct gatacataac
     2341 atccacccct ttgcttttta taatgaaaaa accatccaga tactagtata aacaattatc
     2401 tggatggtga gcataatgaa ttattgaata ttcaagacac gcagactatc ttcaacgatt
     2461 tgttttggtg ttaaatgata acgttcataa agctgcccta caggaacgct atccgtgaat
     2521 tctttctctg caccaaaatt taatacgttc attgaagaat caccataata acgactgata
     2581 ttttcgccaa atcctcctga caaactacca tcttctaatg tgatgactaa ttcgtgtgtt
     2641 tcttttaatt tatctaatgt ttctacgtca ttttctgtga tcgttcctgg attgatcaac
     2701 gttgcttcga ttcctttttt tctaaaagct tttactgttt cttttcctaa ttcaagaaaa
     2761 ccgcctaaag ctaaaattgc tacttttcct ccattattta ctgtttgata ggctggaata
     2821 ctataatcat ttgcgatagc tgtaccatgt tctacaccat gtgtaggaat tcggattgct
     2881 acaggctgcg ctgtttgttc gaacgcccaa tctagcatag agatcatatc ctcttttgtt
     2941 gctggagcaa gatatttgat gttcgggata cttgataagt aaggaatgtc aaatgttcct
     3001 tggtgtgttc ggtcactagc tgagatcgtt ccgccaccga ctaaaataat cactggattc
     3061 tcgttgatcg ctaaatcatg tgataattga tcatatgccc gttgcaagaa agtacttgat
     3121 tggaagacga ctggacgtac tccctgagaa gccaaagcag aagcgaaagt gatagagtgc
     3181 tgttcagcga tccccacgtc aaaataatga tctggatgtt tttcttggaa tgttttcagt
     3241 ccaaaggcgc ctggtatcgc tgcattgact gcggcaatag gagctgtact tgtttgcatt
     3301 ttcttatcca aataatccat gatgatcata ttaaatgttt ctccagaagt tacttgcttt
     3361 gcctccccgg tggacagatc aaatggtaca tgccaatgat atttcatttt attatcgatt
     3421 gccggctgat aaccgcgacc tttttccgta tggacgtgaa gtacaatcgg atgatcaata
     3481 tcttttactt cttcaaataa acggatcacc gtttccagat cgtttccatt atccacgtaa
     3541 cgataatcaa atcccattgc tttaaatagg ttattgctgc ttttaccgtt ggtttgacga
     3601 agctcagcta agtttttata taaactgcca tgattctcat caatagacat ctcattatcg
     3661 tttactaata cgattagatt ggattgtaaa acaccaccat tgttcaatcc ttcaaaagct
     3721 aagccaccac ttagggagcc gtcaccgata aatgctacca catttcctga ttctttcttc
     3781 agatctctcg ctttagctaa acctgttgct aagctgatag atgtagatgt gtgccccact
     3841 gtaaaatagt catgtttact ttcatgttgg ttggaatatc cgctcacttc acggtaatgt
     3901 cctttttcaa aaccattttt tcgaccagtt aaaagcttat gaccataaga ctgatgggaa
     3961 acatcccaaa cgattttatc ctttggtgaa tcaaatacat aatgaaacgc aatcgttaat
     4021 tctactacac ctagattcgg accaacgtgc ccacctacat cgctgtcctt ttgcaagatt
     4081 ttttggcgca tctcttctgc caactgtttc atttcctcaa cagataattt tttgacatct
     4141 gcggggctat tgattgcatc caatacatgt aatactgtac tcataataca ttctctcctc
     4201 cgtactatct tcttttaatg aaaatagatt tgttacactt tatctattct actacttaga
     4261 gttgactcta agtcaatagc attttaaaaa aatttcagag aaagcttgtt atataagtag
     4321 atcttcgcac gaatcaggac tcaaataaaa accttctaca gacaattaaa aagctttgta
     4381 gaaggtctcc taattaaggt ctcatcaaga aatatgtttt tttaataggt gaagttcctg
     4441 agcaatatga tacaaatgga tgtttgcacc ttttaatgag attggataga tctttgtctt
     4501 ttcagtttct aatccatttt gatagctagc agcatcgcac aaaaccactc tttttttcgc
     4561 acatagacat tcatcaggca attcttctaa tgaacgaaat aaaataggat ttatttcagc
     4621 gatgccttct tccgcataca aatgaaattg ggttcgataa aaaaattgtt tgactgaact
     4681 ttctgaaaca acaaaaattt ctatttcctg tctccccgct tgttcactgt tgatcaaaga
     4741 aagacttttg acgaattttc gaatgaaatt ttcattccat cttagttgga tttgattttt
     4801 ctttttccac tcttccaata tttctacaat ttttccgtac agaagttgtt ctttttctga
     4861 tagaagatag atcctttccg gtaaaaatac ttgtccatct gcccacaacg tacggacaaa
     4921 ttgtaaaaag gattgcttga aaataaaatt ttctgcatcg tcgatttcag cgatactaat
     4981 aatctgtaaa atcaattcat tcagtgatag gtcattgaga acaaaatttt tataaacaac
     5041 ttcgaaatct tttcttaaca gctccatgtt ctcattggta taatttctac tgttgaacaa
     5101 agaaaaaata taatagacat cttcttcttg taagtctaga attccttttt gctcttccaa
     5161 tccttgacag actaattgaa ataacggctt cgtttctgcg cttttcttat cttcttcttt
     5221 cagtccaagg ggaaatgcct ttcttccgat tgcgatctct attcctcgta tgataaagga
     5281 cttttcatct tccgaatatc ttcttttaaa aaaatgagtc tctacataat caatcaactc
     5341 gttacaagct tcttctacat acggattttt attttcatag ccttcccaat tgacataacg
     5401 tactaaagct agcaagatgt tccgcgagtc aaattctggg ataatgattt ctttattttt
     5461 caaataatca ttttctttaa aaaaatccaa tacgattttt ttgattgtat atactttgct
     5521 caaagaaata aattcaagat cagccagttc tgtactcgtg aatataccat taaaataata
     5581 acttaaaaac tttaaaaaat aagattgacc gtacagaaac tgtgtgagct cagaaagagc
     5641 aataccatgt ttgaatacga gtttatactt atgcttctct cttacttgtt cttttataca
     5701 atattctaga cactcggcta gactttctag atcgtgaagg atcgttggtg tagtcaccct
     5761 tagagaaata gctgtttgtt cgatgtctat ttcttggaat tcaaataatt gttcacacag
     5821 atacactttt ctaaatatat ttcgctcgat gtaattttcc agcattcctg atacacgcct
     5881 ccagtttttc ttatgatttt atttaatcat atctgtaaat cgtatttttg tttccttttt
     5941 atttagaaaa gccctttcaa aaaccaataa aaaaagaaac tgggacaaaa gtcaaacaag
     6001 ctcacaattt cagcctcatt gtaggtagct ttgagccgtt tggactttta ccccagcctc
     6061 tttcaagaat ggttattcaa agatgtcagc gtctagttct ttgactacat ctttcaacaa
     6121 ttggatacca gctgcgctgt taccaaatgg atctagtgcc gggctgaaga cacctatgcc
     6181 gtaacgattt ggcacagctg ccatcaaccc gccgcctaca ccgctttttg caggtacacc
     6241 aacatggacg gaaaactctc ctgattcatc atacaaacca gcagttgtca taattgattt
     6301 gacgattgta gcactttctt cagtaatgat ttgtttgcca ttccaaggag caattccttt
     6361 atttgccagc acagcagcta attttgctat gcctgtagcg gtgacattga gggagcattg
     6421 tctgaaataa gcatcgagta tctccggtac gtctccttcg atcatttgat tacctttcat
     6481 atagtaagca agagagcgat tgatatcacc tgttcttgat tcagaatgat agatttcttc
     6541 attcaatgtg atattaggat catcacagat ctctttcata aatgacaaga ttcgctcaaa
     6601 tttttcatct gcatctttac cggcaatcaa cgaggttgtt gcaatcgctc ctgcattaac
     6661 aaaaggattc attggatgtt tgcgatgatt gatttccata ttcatgatag aattgaaggc
     6721 aaaaccggtt ggttccgtgt tgattgtttg aaagactttt tctattccgt tgtctttgat
     6781 tgctaataac aatacgggaa cttttgacat gctttcgatg gcaaagcgca catcggcgtc
     6841 tcctccctca atcagttgtt ttgtatccaa atcataaatc gccataccta attgtttggg
     6901 atccacttca gctaatgctg gaatgtaatc cgccacttgt cctgtttgat aatagtggaa
     6961 attttttcca atcaattgtt ctaattcttt tacttccatt tgaataacca gctttcattt
     7021 tttatttttc tgcatgctgg aatttatgac ggcatgcgta gatcgtaaat ggaataacta
     7081 agacgataag ataagaaaca atcagaatcg tttcataaat cccatgctgt ccagctgcga
     7141 tactagcagg tggaacaaat gagatacaaa aagcaaaaag tgaagtcaaa agacctaaac
     7201 aagcaacgat tacttttaca acttttccgc ctggaacctg ataggctctt tcaagactgt
     7261 catctttaaa aaccagcttc aaatagcccg cgaaaaacat aaagtacaac atcaggtaga
     7321 ttacaacagt caatgacatc gctgcaagaa atgaaagatt attccccccg ccgcttaatg
     7381 taaagacggc tgcccagatt gttgcaacga tcccatttgc gatcatcaaa tgagcaggaa
     7441 caccgtgtgt gttttctttt gcaaaatatt caggaagtaa tccttcttct gctgctacgt
     7501 gaagtgcttt tgaaggagag gttacccaag aagcaatttc tccgatgaca cctaaacaaa
     7561 caagaatcgc aagaattttc gcaatccatg caagatttgg atcaatgtgt cttaatagga
     7621 attctaacga ttgaatcacc cctgtattaa gagacaaacc atgttgaggt actgtagtag
     7681 cgacggtcaa tccgccaaaa gtatctaaaa tgattgccag aataaccaat acaaacattg
     7741 ctaatggata atccttttta gggttttcca tttcatttgc atgactggca gatgtttcta
     7801 cgcccatata tgctaaaata aaggaaacaa aaacaaccag cgtaggcaat ttcgaaaaat
     7861 caggaatcaa tgttttcata gacagtatcg tttgtagtgg agcgcctgaa gcgacataat
     7921 ggatccctaa gccaaacaag actaatgctg gcaacaagat accagctaca aaaccgatcc
     7981 gagcaatcaa tgaagtgtat ttggttcctt ttaactgtga gagtaaaata gcccagaaaa
     8041 taatcaatag gattgccaat ttcagatatt tattgttttg tatagcacca atacccgttg
     8101 cataggataa tgcaccagtt aagaaataca gcatggtcaa gtagccaact gttatctcaa
     8161 accattggaa aaagattgcg gcaaaaccga atcgttttcc caatgtgcga ctgacccaag
     8221 tatagacacc gcctttttcc catcctttca ccgttgccat ctctgctgcg cacaatgcca
     8281 cagggataaa ccatagcaaa ccgcctaata acaagaaaaa tactaagctg aagcctgagg
     8341 tcgcgaatgt gggatattca tataatgaaa cgaccattga gatggtcata gccaaaaagc
     8401 caaagaacgt taattttttt gcaggaattt tcgttttgct ttgttgcatg aatcttcctc
     8461 ttttctattt gaatttgttt caattgagtt tgttgccaaa gaagaaaaag tccaatcctt
     8521 cttcttgttc ttcttttgta gtagtgatcg ttgtaaagtg catcgccgat tttaaaatca
     8581 ctgttgtcag cacataggca tacacggcag taatgatgac accaatcact tgaatcccta
     8641 agaagtacca gctgcttgga ttcgttagta aatggctgtt agatgcaaag atccctatca
     8701 gaatcgtacc tgtgaatccg cccatgccat gaacacccca cacatcaagt gcatcatccc
     8761 attgtttctt tttacgaaaa tcaacagcag catgacagac gatacccgca atgatcccaa
     8821 tcagcatggc actttttgct tctacataac cggcacaagg cgtaatggct gccaatccag
     8881 caacggatcc tgttagtacg tcgacaaaat caaagccatt tccttttact tttgcaatga
     8941 tcagccaagt aatcatcgca aatgcaagag cgatgaatgt tgaaccaaat gcattgactg
     9001 cttgttcatc tgctcgaagt gcaccaccgg aattaaaacc gaaccagcca aaccaaagca
     9061 gtcctgtacc gatagcagct gccataagac tgctatgctg acttctttct cctaaaggaa
     9121 tctttctttg accaagtgtg aggatacatg ctaaagagcc gaatccagct gtcgtgtgga
     9181 tgactgctcc accagcgaaa tctctaaatc ccatctgatc caaaaatccg ccaccccata
     9241 tccagtggca aacagggaaa taaatcagca gattccaaaa aataacaagt ataatatagc
     9301 cttttaaatt caatctccct gcaaaagctc ctgtcatcaa aggaacggta atcacgataa
     9361 acatcagttg gtaaagaaag aacattaaaa atggaatcgt tgcaccatga aacatgttgg
     9421 ggaagcttgt aacatgtctc atcaaaaaga aatctgccgg gtttccaata acaccgccga
     9481 tatcccgtcc aaaggccaat ccgaatccac caaataccca cataatcgtt gttatcccaa
     9541 cggagagaaa agattgagac atgatcgtta gtatattatt cttccgtgct aatccgccgt
     9601 aaaaaaaagc tagaccagga gtcatcaggc aaaccattgc tgtacataaa atcatgaatg
     9661 ctgtatctcc tgtattgata ggtaatgtat tcattttttt cgcctccttt ctacgattac
     9721 gagtataaaa gaaggtgtag ttgttttttt cttctgtttt tttgaattaa tacttgcatt
     9781 tataaaagac agacaattaa taaaagcttg atgtgttgtg ctctttttcg tttttcacac
     9841 aaataaagac aaaaaataaa cggtcttctt tttatagaaa accgtttatt ttcgtctttt
     9901 tttattttta aagatatttt ttcataagga ataaagaata cttcatataa aatatataaa
     9961 aaagaaccgc agcgagtgtc gctacggttc tcaaatttgt tcttcatttc aacataagtt
    10021 tttcttcaat ttgcttataa tttacgtgca aagaatgaaa cgactaatac taaaatgatt
    10081 gcaccgatca atgatggaat gatagccatt cctgcaattg ttggtcccca agttcctagt
    10141 aaagcttgtc caattgctga acctactaaa ccagcaatga tgtttgcgat gatccccatt
    10201 gatgatcctt tattcgtgat tgctcctgca attgctccaa tgataccgcc gacgattaat
    10261 gcccaaataa atcccatttt aaattcctcc taactgactt cttacttctt attgtacacg
    10321 tggttcgtta ttttctttga ctttttgtgc acctttgcct acagcagatt ttgctttatc
    10381 tgtttggcgt gaagcaaatt gtcctgtgga ttttgctgct tctgttactt tgtcttgtac
    10441 tgtttcttga tctttttggt attcttcttg tgttttgatg tctgcaacat tcacattcac
    10501 ttcgataaca tctaaatgtg tcatattgtt tacttcagta ctgatcaatt ctttgatttg
    10561 gttgtaaata tcttcgatgt ctttaccgta ttctacgatc acatctagat ccacagctac
    10621 ttgtttctta cctacttctg tattgatacc tgctgttacg ttatctgtgt tgactaattt
    10681 ttcagccata tttgagaaaa atccgccatc taatgtcaat agaccatcta catctttcaa
    10741 tgcataaccg atgatttttt ggatgacttt gtcttcataa gtcaattcac cattcatcat
    10801 gcggttttct cctttttcat ttgccaaaac tgatccattt gttgtattca tgtttttgtt
    10861 ttccatcttt gtttcctcct atgatttaaa aaattgatca actattcctg actgtttcaa
    10921 ataaaaaccg attcctgcgc caattgctgt catgattatg atcaacaatg tcttgaaaaa
    10981 tccaatcgtt aaccataaaa cagctagcag tagtccaaga cccccaaaga taatagggag
    11041 cttgtatgct gaaaatagtt ctttcattat ttggccctcc tattccactc gagagtgctt
    11101 gtagtctctt gtatcttctt gttcttcata accgctgtat gtgactgcca ctttgaccgt
    11161 ttcttttgtt ccgagtactt tagttacttc ttcttcgata tcttgcatca atacacctgt
    11221 tttccctact aatgaagaag ttcgtttcaa gtctccgttg acatggatat ggattcgatt
    11281 tttcgttgaa cgtatccgta ctttaggtga atgaatgaac tcttcttcgt gtaaatggga
    11341 acgtaccaac ccttcgatcg cttttttgtc gattgttagt ttgccatctt cccgtttcat
    11401 aacgaaagtt cctcttgact ttggatagaa aagaacgact agcaagatga taatagcaag
    11461 aacggcaaat actacagctg cccagaaaat atattgttgc atgtagtaat tcgttaaagt
    11521 aaagaagcga aatcgttcca attgttcagg cataatatac ggcgcattga tcaacgcaat
    11581 cgctagaaat actgaaagta gcagtaaact catgataaca ccgattattt ttaacccctt
    11641 attcattttc cacctcctat aaacttattt ttaccctgta aataactcta ccgacaatca
    11701 cagtatagat agcgaacagt tagcatagca tcagtaaata aagcgctacc aaacattgct
    11761 ggatcataac ggcgttttat tgccagtctg atactgaaat aacaattgct tacttattct
    11821 ctatttactt ttgattgctg gctatactta aaggatatta ttcaagatta aaaattgcaa
    11881 agattatgct cagttattat tacaagattc tatttatt
//
LOCUS       DADQCX010000082        11837 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.083, whole genome shotgun sequence.
ACCESSION   DADQCX010000082 DADQCX010000000
VERSION     DADQCX010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.083"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(560..1600)
                     /locus_tag="J8R83_002144"
     CDS             complement(560..1600)
                     /locus_tag="J8R83_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAZ9575263.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="J8R83_002145"
     CDS             complement(1949..2275)
                     /locus_tag="J8R83_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575264.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3050)
                     /locus_tag="J8R83_002146"
     CDS             complement(2262..3050)
                     /locus_tag="J8R83_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9575265.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3418..3708)
                     /locus_tag="J8R83_002147"
     CDS             complement(3418..3708)
                     /locus_tag="J8R83_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAZ9575266.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3844..4023)
                     /locus_tag="J8R83_002148"
     CDS             complement(3844..4023)
                     /locus_tag="J8R83_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575267.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4020..4370)
                     /locus_tag="J8R83_002149"
     CDS             complement(4020..4370)
                     /locus_tag="J8R83_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575268.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4363..5688)
                     /locus_tag="J8R83_002150"
     CDS             complement(4363..5688)
                     /locus_tag="J8R83_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAZ9575269.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6138..6752
                     /locus_tag="J8R83_002151"
     CDS             6138..6752
                     /locus_tag="J8R83_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575270.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6917..7159)
                     /locus_tag="J8R83_002152"
                     /pseudo
     CDS             complement(6917..7159)
                     /locus_tag="J8R83_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7363..8682)
                     /locus_tag="J8R83_002153"
     CDS             complement(7363..8682)
                     /locus_tag="J8R83_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAZ9575271.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(8837..9424)
                     /locus_tag="J8R83_002154"
                     /pseudo
     CDS             complement(8837..9424)
                     /locus_tag="J8R83_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10062..10319)
                     /locus_tag="J8R83_002155"
     CDS             complement(10062..10319)
                     /locus_tag="J8R83_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAZ9575272.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10312..10581)
                     /locus_tag="J8R83_002156"
     CDS             complement(10312..10581)
                     /locus_tag="J8R83_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9575273.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(10712..10891)
                     /locus_tag="J8R83_002157"
     CDS             complement(10712..10891)
                     /locus_tag="J8R83_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575274.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(11272..>11837)
                     /locus_tag="J8R83_002158"
     CDS             complement(11272..>11837)
                     /locus_tag="J8R83_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575275.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3603 a         2162 c         1789 g         4283 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aacgaatgaa gcaggtaatg attttattct acgttgtcgg gttatccagc ttgcaaccgt
     3601 tccttgtggg taggcatata actcacaaaa ttgttctaca gtgattccta aattcttgat
     3661 aatgtaaaca ttgatcgggt gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc
     3721 tactttcttt tattattgcg tttgcaataa tagtttaaca cacgcattat tctagtatct
     3781 actcctattt gtaaaaacaa aaaaggattc atagagataa ctctatagaa tccgtaaaat
     3841 accttatata tataacggga agatataaaa cctaaaatta tgataacctg ctgcagcttc
     3901 tacatagaaa gagaagcgct caacaccaac ctcatttatc aaacgttggc cataacccca
     3961 aatctcttct gatagctgat caaaggttat atactttagc tcatattgct ggataatgtt
     4021 cattctaatc gactccattt attatcctgg taaaattcga tatgacgtat ttcgtcgtag
     4081 tgaattttgt cttttccaac gtagatcccc agctcatcac tacctaagat cttgccaatg
     4141 atatcttctg gatagtatcc ttcagcgttt cgttcttctt tttgaataga tactgatcta
     4201 ttttttatga ctgcagcgtt caatacttcc gcaatctctt cagtcgtcat ttgttctttt
     4261 gctaaatttt gactggttcg ttgttcattg tcggcatcaa tttcttcagt atgatcagat
     4321 aaataaaacc ctgcccactt taaacgtcca cgatcattgt aatcaatcat ttttaattcc
     4381 cccatttccg cccgcatgac caccaacaag tgtgcttcta gtaatgcttc tagcgccttc
     4441 taacattgaa gaagcatgta caatcgacgt aaaaccatat ttttgccgaa tcttgtcaat
     4501 aattttatct aaattttctt cgtcaatttg cttttgtgga tcactaaata aatccagctg
     4561 aagcgaatcg gtgtacacaa gcttgctata ggttattcca acatgcctta cttcttgtcc
     4621 ttcataatac ttatcaaaca agaaaagaca ataattctgc aattcctttg tattatctgt
     4681 gatagggatc ttcatctggt gtgaaaaccc tggtctcgtt tctaagatcg acgtgccaat
     4741 gtgtaaatgg acacaacctg ttttacagtt atgctgccta atgcgtatcg ctacttgttc
     4801 cgccatttct tttaccacca gctcgatttc atttcttcta gtataatctc gtggtaacac
     4861 ttgtgaattt ccatatgatt tttcctttgt cggttctggt gggattgcta tatctgttcg
     4921 atcgatccca ttagcatgga agtacagctg taagccaatc acacctagtc tattcttaat
     4981 cgtataagga ttccagttag caagatctct aatgctcata atccccatct gattgagtct
     5041 ttttttcatt cgagagccaa ttccccaaaa gtccgtcatt tcaggaatat tccatacttt
     5101 ttcaggaacg ttttcgtacg tccattccgc aacaaatcct tcattatgct ttgcttcgtt
     5161 gtctaaggct agtttagcca aaaggggatt atctccgaca cctactgtag caatcaatcc
     5221 tagctcttct ttaatattct cctggatcat ttgagccagc ttctttctcc gttgacttcg
     5281 tgttccttca gtcgtaaaaa gattcagtga tcgggtcact tttaagattg attcatcgat
     5341 cgagtaaatc agtagatctt catcagccac atatcttctg aaaatattat ttacctgcat
     5401 atttcgcttg atatataggt tcatacgtgg tggaacaacg tgtagtgttt taggaaatgg
     5461 ttgtggtaag tcacgtggtc tactcacatt tgtaatacca taccgctttt ttgcttcagg
     5521 agaagaagct aatatcaatc ctgaaccagt attatcagct cgactcataa caacaagttc
     5581 tgttgttaat ggatctaaat ttctttctat acattcgaca cttgcgtaaa agcttttcat
     5641 atcgattaaa aagtaatcat ttactggctc ttttgaataa tccatcataa ataacactcc
     5701 attctttcac attatacaaa catatgttcg atattgtaaa gaagaaatag ctaaatacat
     5761 aaaaaaagaa gcataggtat gctatcaccc tgcttcttct tttgatttgt atgatcaatt
     5821 tattctatca ctttactaat taatttgaaa atctaataaa aactctcact ctaaaagagt
     5881 gagagactgc aaattagagt acggactttt ttggagttcc gttctttaat attaacaaat
     5941 gaataaaatc cttacaacat ttgagaataa gttatcagta gacacttaca aaaaattctc
     6001 atactatttc ctccatcatt agtttttgtc tatataaggt ttaccctaaa tagacactgg
     6061 tataacattg aaaaatatgg cttcctcgtg tatgattagg gtgtatttta aatagttgca
     6121 gaaagtaggt aaaagttttg agagttgcat acatacgtgt ctcatcgatc gatcaaaatg
     6181 aacaacgcca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc atcgagaaac
     6241 aatctggcgc aacgattact catcgacctg ttttccaaga agcattagat tacgtccgag
     6301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattat gacgagatca
     6361 tcgcttcagt caattacttg aagaagaaaa atgtgaagct gatcattact agtttaccga
     6421 tcatggctga agcaattggc aatcctctcc tggataaatt cattaaggat ctgatcatcc
     6481 aaattttggc catgatcgct gaacaagaac ggactgaatc gaaacgtcgc caggcacaag
     6541 gaattaagat cgcaaaagca aacggcgtct acaaagggcg gcccaaatta tacagtgcag
     6601 acgcaaaaga tccccaacgt cgccttgttt acaaaagcat cgttgaagat cttaaaaatg
     6661 gtgttgcgat tgctaagatt gctaaagact acaatgttac gagacaaacc gtgtatagaa
     6721 taaaaaaaga cagcatggtc aatgacaaat agttgatcat gctgctttta ttatcttctc
     6781 atctttaatt tcctacatat aattactatc tataaaatta agtcttactc agaacagata
     6841 aagcataaaa ttccaacaaa ccatttttta cttaactaaa taaagagtct gttaatataa
     6901 tcttcactta tttacgttaa tcccctactg tatttgttgg ttccttatct atattttcta
     6961 caaaatcctt attatcttgt gatttagctt cgtataattc tttgtatgtc gacacattgg
     7021 ttatactaat tcctatagct agttcttgag actctacttt tctctctagc tcctttgaca
     7081 aagtgatttg agatttattt ggttccgttg gagtcaattc tatagattct tcataaaaat
     7141 ctctatacat aaagctatcc ctgaataatt catagcttta attctttggc acattttatt
     7201 gaaatatgta tcactaatat ccctatcaac tgattttgac taaaaagtta cttcaaacat
     7261 tcactgttca aaaatattga ggaataaatt ttgggtgtaa ggcattttga gcatacttct
     7321 ccctggataa cttcccagta aaaaaatcgt tagattgttg gattagatcc attgactggc
     7381 tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga tacacatgat aactagataa
     7441 tttgagatag actcgtctac ccgtttggac taatttccca gcaactttca gaaacttcaa
     7501 tcgaatagaa tgaatggtca ttcccttttg gacttcttca aagccaatcg ttcttaagaa
     7561 gttgactaag ttgtaagcta tcaagctgag catcattcgg acatgattct ccaaaaagcg
     7621 aggactgtct gttttgtcaa agtaaaagcc agctttcgct tctttaatga agttctccat
     7681 tgtgccacgt ttggcataga tagaaaagat ggtatcagga gaaacatttt ctgatagatt
     7741 cgtcacgata aattcatgtc gaaagagtag ttcgcccgct tcacgtgttg agcgtataca
     7801 cacgcgacga ctttgtgacc aggattgtgc ttgataagtg gtcgagaagt actgaacttc
     7861 tcgttcttcc cacttttgat tatcgccata aagtactgat ttctcagcta tttgacctag
     7921 tctacgatta ttcttcagtc gaataacata atgactcttt tttgattcac acgaatcata
     7981 cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag atgtcagtgt ttggtagaga
     8041 gtgattatag tgctctaata aaggtgtgag aaactccttt acgccttttg atgtatattg
     8101 atttcctgaa cgtagttcag cttttaagaa gtcaccagtc aatccgtcaa aagctaccaa
     8161 tggatggtaa ccataggttt ggtagtgtgt attataattc gtttgttctt ggtgaccaaa
     8221 tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc gtatcattac ggatgaggcg
     8281 tgctttatcg ataagttctt ggttcaaagc ttgaagttca tggatattct cctcagatag
     8341 tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt tctttcctat ctaaaacagc
     8401 tttaaacaca ggatcttgtc tcaggagatt agctgcagaa tcagctgagt aaccagcaat
     8461 taattgcata atgaactgct caagtatgga taagttgtca tgagtaaaat acgctcgttc
     8521 gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa ccaaagatgt tcatcagctc
     8581 tttcactagg acgagacccg aatcactcga taattgacca cctgtatgag aaatagtgat
     8641 atttgaattg aattttactt ggtttttgtg taagctagtc atgaaaagaa ctcctttctt
     8701 ttggttggtt tagtcacttt aaccatagca gaaaggggtt cttttttcat cacttaacgg
     8761 gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt ttcacatggt tttaattaaa
     8821 agtatgaatt attcaggcta tcattaattt tataaaaaaa attaaatgtt tttagcactg
     8881 ccatataaca ttcaaaacat tcttctatag ttggtttact tccttgagga gaatgaacca
     8941 atttattacg tttttctatg aaatttttaa tttcctttct tatttctttc ggaaactcaa
     9001 tattaaagta ccctttaaac atgctcccta ataatttgtc tacaggggga gattgtaaat
     9061 tctcaaatat tagagttaaa tcaggtttct cttgttgata aaattccttt acccctattt
     9121 cacaggctgt aattatcgaa ataaacctat ctctagtatt tgatatattt ttacttcttt
     9181 taaggagtat aagagaaaag gggatacttt cgtgtccatg catgtaatta actaattgtt
     9241 gagcttcaga agttatatct ctaattatat agttaacgga attaggaagt gtctttaact
     9301 ctaatgaaat ttctatccaa ttactatctt ctaatctgta tatgctcgaa gtataatttg
     9361 attcgtcagc aagcatcgct acatcccaaa cactgatcat aaaatctttt aaacgttcaa
     9421 tcatttcagc aatattgcta aaatcagcta atttttcttt agaataaaaa aaaacattta
     9481 tatcagaatc aataaattct atttttttat tactatatcg tcatcattat cttgaccatt
     9541 tatgtttatt gttccctgag tggggagtac ttctttcaaa ttcaagttaa atttatattc
     9601 cattacttct cctccaatat ataaaaatta cttaactgta tccaaattta atatgtaaat
     9661 aaatcattaa tttttagcta aattctatga gaagtttatt tttgttgttt ttgctaatta
     9721 actaaaacta gtacaaaaaa tttaaaatag attattaaac ctattgctta ttctattcag
     9781 tcatatatat aagcgtcatc ctttagtaac taacatccca cactacaata gtattataac
     9841 atatctattc aacttcaaat tgttgaaatt taagccattt atatttactt ttcctcaact
     9901 ttagaaatga ttttactaac cttatatccg taatacgcgt aacaaacaca ttcattaata
     9961 acaatcaaca ctaagctata ttagcttttt aaatgactag ggtaaataaa ataaggatca
    10021 aaaactttta agtttctgac cctttcctta cttccgattg gttaatagtg atcttttgca
    10081 gaataaataa atatcgtttc attttcaact ctatatatca gtctatgttc atctgtaatt
    10141 cttctggacc attttccaga taaatcatgc tttaatggct caggttttcc taatccagca
    10201 aagggggaac gatcgatatc ttttattaac ttgttaatct tttttatatt gcttttgttt
    10261 ccttgctcat gccaataaag ataatcatcc caagcatcat cagaccaagc cttaatcatc
    10321 agattcaacc tcgattaagt catgtgtttt aaatgcacct ttggagaatt gttcatctcc
    10381 tcgacgaatt ttttccatga cgtaattatt agaaagtgtt ctcaacgttt cttgcataga
    10441 atcataatct ctttttgata atacaacaac tgtatcttct acatctttac ttgttacaat
    10501 aagtgtttca gcatcctcat taacttgttt catataacta cgtaaatttt ggcggaaatt
    10561 tgaataagct actgcttcca ttcctttcac cccttattta tttctataaa acaattgtac
    10621 attatattgt acaattaagc aaatgattaa tattctaact tcttataatt aaaagtgcta
    10681 tcacttttag tttttaggat aaaaagtgac gtcacttttt gagtgctggt acctcaaatc
    10741 ctgctttttc ttgggcaatc aataaatcta acgcaataca cataatcctg gattcacttt
    10801 tgccgtactt ctgctttagt tgctgcaatt ctttttgtct cttttcatcc aacgtaacgg
    10861 gtaaccgttt atttcctatt gcaattggca ttagtactct ctcctttcat cgaaataacc
    10921 ctatgaaaaa tatggctgca atcatcttga atagtagact cacaagggct aatacaaagc
    10981 gccaaaagat caaacaaaat accagtattg ccaaaaatac tacgaagttt aaatgcacag
    11041 ctgcagcatg gcgcataagt atttcgccaa caaataggac taacaataga ggaatgattt
    11101 tattcatatg gatctccttc tttctcttag gttatcgggt gttgcccgct tatttcgcac
    11161 cacctaagcg gcgggggcgg ttggagcgat tggtgcgaaa taagaaccat tcccttagtt
    11221 actaggtttt ttgtccttat ttcacacatt ctcacttttc ggtataaatg attattgcct
    11281 ttttttcctt tcaaatcgtt gatatggcat tcgtttacgg tcaagttcat tttggatttc
    11341 ttctgtatcg tcgtaagtat aggtgtctaa aaaatcagtt aaagtcgtgt accagtcgtc
    11401 gcctgggtta tctacttctt ctacatattc cctcaaaaat gcttcgggta cagcgagttc
    11461 ataatccatt cccattaaca cgatagattc cgttccacac gtcaaaaatc tagtaaatac
    11521 aaggtaataa tcgtctatcg tcgcatcttt gctgtttagc tcttccattt cttcttccat
    11581 taattccatg ctctcaaaaa ttgaataata ttctgattct gagtaatagt gtttcctgca
    11641 aatcgtgtag ctgacaaagt tttcgaccag ctcactcctt tctaggtaaa cattcatgat
    11701 gtatttttct gtttctagtc gtagaagctc cgttcctttt tttaccgttt caggacgacg
    11761 tttatacacg tctaaacgat tatggctgac tgtgaccttc gtttgactcg tttcactttc
    11821 caaatacaat tgttctt
//
LOCUS       DADQCX010000083        11612 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.084, whole genome shotgun sequence.
ACCESSION   DADQCX010000083 DADQCX010000000
VERSION     DADQCX010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.084"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(105..629)
                     /locus_tag="J8R83_002159"
     CDS             complement(105..629)
                     /locus_tag="J8R83_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575276.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="J8R83_002160"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="J8R83_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAZ9575277.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="J8R83_002161"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="J8R83_002161"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAZ9575278.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="J8R83_002162"
     CDS             complement(2351..3031)
                     /locus_tag="J8R83_002162"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAZ9575279.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="J8R83_002163"
     CDS             3157..4026
                     /locus_tag="J8R83_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9575280.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="J8R83_002164"
     CDS             4052..4567
                     /locus_tag="J8R83_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575281.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="J8R83_002165"
     CDS             complement(4614..5177)
                     /locus_tag="J8R83_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575282.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="J8R83_002166"
     CDS             complement(5232..5411)
                     /locus_tag="J8R83_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575283.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="J8R83_002167"
     CDS             complement(5488..5997)
                     /locus_tag="J8R83_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575284.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="J8R83_002168"
     CDS             complement(6093..6473)
                     /locus_tag="J8R83_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAZ9575285.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="J8R83_002169"
     CDS             6803..7552
                     /locus_tag="J8R83_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAZ9575286.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="J8R83_002170"
     CDS             complement(7736..9013)
                     /locus_tag="J8R83_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575287.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="J8R83_002171"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="J8R83_002171"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAZ9575288.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="J8R83_002172"
     CDS             complement(9935..10879)
                     /locus_tag="J8R83_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAZ9575289.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="J8R83_002173"
     CDS             complement(10881..11567)
                     /locus_tag="J8R83_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAZ9575290.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3308 a         2460 c         2046 g         3798 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcata acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgcggg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag ca
//
LOCUS       DADQCX010000084        11584 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.085, whole genome shotgun sequence.
ACCESSION   DADQCX010000084 DADQCX010000000
VERSION     DADQCX010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.085"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(279..764)
                     /locus_tag="J8R83_002174"
     CDS             complement(279..764)
                     /locus_tag="J8R83_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAZ9575291.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            1244..1885
                     /locus_tag="J8R83_002175"
     CDS             1244..1885
                     /locus_tag="J8R83_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9575292.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1904..2539
                     /locus_tag="J8R83_002176"
     CDS             1904..2539
                     /locus_tag="J8R83_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575293.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2557..3372
                     /locus_tag="J8R83_002177"
     CDS             2557..3372
                     /locus_tag="J8R83_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9575294.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3691..5127
                     /locus_tag="J8R83_002178"
     CDS             3691..5127
                     /locus_tag="J8R83_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9575295.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5316..7763
                     /locus_tag="J8R83_002179"
     CDS             5316..7763
                     /locus_tag="J8R83_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAZ9575296.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQPKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7993..9060
                     /gene="rlmN"
                     /locus_tag="J8R83_002180"
     CDS             7993..9060
                     /gene="rlmN"
                     /locus_tag="J8R83_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAZ9575297.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9253..10356)
                     /locus_tag="J8R83_002181"
     CDS             complement(9253..10356)
                     /locus_tag="J8R83_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9575298.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10909..11457
                     /gene="aac(6')"
                     /locus_tag="J8R83_002182"
     CDS             10909..11457
                     /gene="aac(6')"
                     /locus_tag="J8R83_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAZ9575299.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3851 a         1952 c         2492 g         3289 t
ORIGIN      
        1 agtttagtta gaatataata ttttttgtta aatatgactg aaatcaaaag aataaaattc
       61 cgatttataa tcgaaaaaag aagcattttt atatatgctt cttttttcgt agaatcaata
      121 aatatggatt tggctaacta tggaagaata ctcgtattag ttttcagcgt tcatactagt
      181 tgttacattg tttgattggc caaaagaatt tctgatatat tttgtgctaa ataaagaaaa
      241 agacgcttga attgggaaat aagaaaacta ctctatcatt acaaattttc ataaactggc
      301 agatgttcta agtaaacaag tatcttttca aagtcggaaa aatccataat caacgtagtg
      361 gtattgatat ttggatgaaa gcctacggta tcttgacgat caatagcagc atcgatcacg
      421 acttggattt ttttctcttt gtcgtgcatc aatgctaatg gagtcactgt acctgctgga
      481 acgcctagga ggtcaggaag ctgttcttca gaaacaaaag ataagcgctt ttcttttaat
      541 tgttcagcta gttgttttaa atcggcgtgc ttttcatcag gcaagatgac aagatagatt
      601 tgttttcctt ttcttgattt caataataga ttttttactt gcggaccagg tagggaaaaa
      661 gggacatttt tgactgacgt aatcgcagga tgatcgactt tttgaaaaga gatacccagt
      721 ttttttagta gttcataagc ttcttgttcg gttgcacgac tcatcgcgca tcaccctcct
      781 ttttttatta gtgtatcata aaaaagagtt gacaaatgaa aaataatcat gtaaattaca
      841 cgtaaagtta aaacaaatga catcgaaaag aagagtagcc gttaggtgtt tttagagagt
      901 ctctggttgg tggaaagagg cagcagttaa ccgtgaaaca catcttggag tcgattttct
      961 gaagcgtata gtaggaaaat ccggggagcc cgttacagct gcggtcgttg ctagatgacc
     1021 agataaggct ggcttttccg tgaggagtcg gtaaaaaaag gtggaaccac gtgattaacg
     1081 tcctttgatc ttcggatcaa aggacttttt gttttcatct gaacggcaac gactgtgtga
     1141 ggttttttct gcaaggaaaa aataaacaga ggtggaacca cgtataatac gtcctcttgg
     1201 catttgccaa gaggattttt ttattttaaa ggaggaaaag aagatggagt atttgattga
     1261 agttatgccg caattattag taggagcact cacaacattg aaattatttt tatttacctt
     1321 gattggctca ttaccattag ggattgtttt agcattagga ttgtctttgc attttaagcc
     1381 gctacgctac ttgcttcaaa catatgtatg ggttatgcgg ggaacaccgc tgttgttgca
     1441 actgattttt attttttatg ggttgccgac gattgggatc gtttttgatc gtttcgaagc
     1501 agcactcatt gcctttatct taaactatgc agcttatttt gcagagatct ttcgtggagg
     1561 gatacaatcg attcctcaag gtcaatatga agcagcgcaa gttttgcaat taagtccctt
     1621 tcaaacggtg acgaaaatcg tcatcccaca agtgacaaag attgttttac cttctgtagg
     1681 gaatgaagtt atcaacttgg tcaaagattc ttccttgatc tatatattag gtttaggtga
     1741 cgtaatgcgt gctgggaaaa tcgcgatgga acgcgacgcg actttactgc ctttgctagg
     1801 cgtggcaatc atctatctta cattgactgg tattctaaca atcgtaatga aacaagttga
     1861 aggaaaatta aattattacc gctaactgat aggaggaaga aatatgattg aattgaagaa
     1921 agtgaacaaa gcatttggtg aaaaaaaaat aatcaaagat ttgaatctaa tcattccaga
     1981 tgggaaaaca ttagctatcg taggtccttc cggtggcggt aaaaccacgc ttttacgtat
     2041 cttggctggc ttagaaagtt ctgacagcgg agaattttat ttagacggtg taccgttcaa
     2101 cccattcgag cttaaaatga aagaacaagt tgtaggagtc gtattccaag acttccagct
     2161 atttccacat ctgaatattt ttgaaaacat taccttagca ccaaaaatgg tattgaaaca
     2221 gacaaaagaa gaatacacca aaaaagcaga agaattagcg gcttcattag ggattagtga
     2281 tttattgaat atctatcctt atcagctttc tggcggacaa aaacagcggg tagcgattgc
     2341 cagagcattg gctatgaatc cacgggtatt ggcttatgat gaaccaacaa gtgctttaga
     2401 tcctgaatta cgccagcaag tcgagcgttt gatcctatca ttgaaagaag atggggtaac
     2461 ccaaattatt gtcacccatg atttagtatt tgcagaaaat gtcggtgatc aattactaaa
     2521 agtttcccca attcattaag aaaggagaag atagagatga aaaaaaccag ttttctattc
     2581 gctttgatcg caggtcttct tctttttgca ggctgttcga acaaaaaaac ttcagcagat
     2641 aattgggcga ctatcaacga agagaaaaaa atcgttatag gtttagacga tacatttgtt
     2701 cctatgggat ttagagataa agacgggaag ctcacaggat ttgatattga tttagccaaa
     2761 gcagtctttg aacaatatgg gattacggta gactttcagc ccattgactg gtcaatgaag
     2821 gaatttgaac tgaacaatgg aacgatcgat ttgatatgga acggctattc caaaacgccg
     2881 gcaagagaaa agaaagtgca atttacaaaa ccttatatgg aaaacgatca agtgctgatc
     2941 acacctaaag aatcaggaat cacaaacttt ggacaaatga ataataagag attaggtgcg
     3001 caaaatgggt catctggtta tgatgtattt acgaaacaac cagaagtatt aaaagagata
     3061 gtcaaaaacc aagatgctgt tttgtatgat agttttaatg aagcattgat cgatctgaaa
     3121 agcagacggg tcgatggtct gctgatggat aaagtatacg cagactatta tttgaaacaa
     3181 agaaacgaac tagaagactt caacataaca aaaggttctt atgagagtga ggattttgca
     3241 gttggtgcac gcaagtcaga tagtacatta gtgaaaaaaa tcaatgaagc cctagatcaa
     3301 ctagagaaaa caggtgaatt ccaaaaaata tccgataaat ggtttggcga agatgttacg
     3361 ccgagaaatt aacaaatagg ggactgtgac aaaagacgtg tcacagtccc tttttccgaa
     3421 taaacagtgt tctcctgcca actccttgtg actcggagct gaatggcagg ctcacaacct
     3481 cttggtaaac ggtgttcaaa agccagtttt tcggtattaa gccaaattta tgcaaaaatg
     3541 tagaaagcca ttttcacaaa atttttctta ctactcgaaa ctaagcgact ttttcacaac
     3601 ctcctttaca taattttatt ttgttgtgga aggggtttcg tgttattcta aaagaggaac
     3661 gattgaaggt tataggaaag gaagagatga atggaacaca aagaacttac ctcatttcca
     3721 aaagattttc tgtggggctc tgcttctgca gcgtatcaag tagaaggagc ttggcaagaa
     3781 gatgggaaag gagaatcagt ctgggatcga tttgtacgga tacctggaaa gacatttaaa
     3841 ggaacgaacg gtgatttggc agtagaccac tatcatcgtt ataaagaaga tattgcttta
     3901 atgaaagaac aaggtctgaa agcttaccgc ttctctgtag cttggacacg gatttttcct
     3961 aatggacgag gagaagtcaa tcaagctggg ctcgcttttt atgagagatt gatcgacgaa
     4021 ttgattgaaa acgatattga acctatgttg actttatatc attgggatct tccacaagca
     4081 ttgcaagatg aatataatgg ttgggaatca cgtcagatca ttgaagattt cactcattat
     4141 gcagaaacat tatttgaggc attccgcggg aaagtccatt actggattag tttgaatgaa
     4201 caaaatatct tcacttcatt aggttatttg ttagcagcac atccgccagg tgtgacagac
     4261 ccgaaacgaa tgtatgaagt taaccatatt gctaatttag caaatgcatc tgtcatcaat
     4321 aaatttcacg agttagaaat gcctggaaaa atcggaccaa gctttgcgta tacgccaaat
     4381 tatccaattg acagtaatcc tgaaaatgtt ctggctgctg aaaatgcaga agacctgatg
     4441 gccaattatt ggatggatgt ctatatgtgg ggaaaatatc cgattgctgc catgaggttc
     4501 ttagaagaaa aaggatgggc accaacgatt gaagctggcg atgcagaatt gctagaatct
     4561 gctaaaccag attttcttgg gatcaattac tatcaaacgg cgacgaatgc attcaatcca
     4621 ttaaacggag ttggtgctgg aaaaatgaat acgacaggaa aaaaaggttc atcagaagaa
     4681 actggagttc ctggaatgta taaaaaagtt gagaatccat ttgtcgaacg aacaaattgg
     4741 gactgggaga ttgacccaga aggattaagg atcggactgc gtcgtatcac aagccgttac
     4801 cgcatgccgg tactgattac ggaaaatggc ttaggagagt atgacaagtt gacagaagat
     4861 aaacaaatcc atgacgacta tcgaatcaat tacttacaaa gccacgtcaa agccatcaaa
     4921 gaagcaattt cggatggagc agaagtccta ggctattgca cctggtctta tacagatttg
     4981 cttagctggc tgaacggtta tcaaaagcga tatggatttg tatatgttga tcaagacgaa
     5041 acacaagaag gatctttgga acgatataag aaagacagtt attactggta ccaaaaactg
     5101 attgaagaaa atggagagaa cctttagttc acatacttaa aacaagaagg tacggctgga
     5161 tatggccgtg ccttttcttg ataaaatcat ttagaaatta agaaaaactg taaaataagc
     5221 tgaaaaatga aagaaagcgt cagttctttc aaacaaaact ttagttccct tacttttttt
     5281 tgtataatga aacttgatga aatgagggat aataaatggc acaaaagaaa cggcctacta
     5341 aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca gcagcaggaa caaatgctga
     5401 cgattggtgt tgggtttgcc ttgattttat ttgctgtctt cggcttttta aaattaggtt
     5461 ttttaggaat attgattgca aacggctttc ggatcattgc aggaaatact taccaaatcc
     5521 tctgtctttt attagccgta ttaggatttt ggattgtcat taagaataca gagttttcaa
     5581 ttggtaaaaa ccgacgctgg tttggcggca tactctttta tttcggtatc ttattattgt
     5641 tacatgccca tttatttggc aaactccata ctggggaacc aaatatcatg gggacgacat
     5701 gggatttgtt agccagtgat ataaaacaaa gtcaagtaga caataacgtt ggtggtggga
     5761 tgattggagc aatcctttat cattttactt acttcttgat tgcacagcct ggaagttatt
     5821 tagcagcagt gctattactg gcaggaggag cattcctgtt cagtaatctg gaaggctatc
     5881 agctgttaaa tggtatccaa tcaattggag aacgagtaca ggaattattg gaaggtgatc
     5941 ctgccaagca agctcgaaag caagcggcaa aggaagagag aatgaaacag cgcgcagaag
     6001 cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga aaaagaagct gcagaatatg
     6061 agaagaaaaa agcggtgagc cagcaaaggg aaaatactgc tgatgaatgg caggaaccag
     6121 aaaatacaga gccggagcag ctaagttttg ttccaatcga cagttttcaa gaaaatatcc
     6181 atcctgcgaa tctagagaaa ccagtaccag atacaccaaa acagaccaat acagcagaag
     6241 gtttttcaga tgagttgcca gaggatgacg gtacctcatt agaatttgag attgaagcag
     6301 aacaggaaaa tcaagactat gaattaccga cagttgattt gcttgattct ataccaactg
     6361 tggatcaaag tgatgagtat aaaaaaattg aaaaaaatat cggcgtatta gaacaaactt
     6421 tccaaagttt cggtgtcgat gccaaggtcg tcaaagccag cttaggacca tccgtcacaa
     6481 aattcgaagt ccagccggct gtaggggtaa aagtaagtaa aattgtgaac ttaacagatg
     6541 atatcgcgct tgctttagcg gcgaaagatg tccggatgga agcaccgatt ccaggtaaat
     6601 cactgattgg tattgaagta ccaaatggaa agatcagtat ggtttccttt agagaaatca
     6661 tcgaagcaca accaaaccac ccagataaat tactagaagt acctttagga cgtgatgttt
     6721 ctggacgggt acaaacggct gatctttcga agatgcctca cttactcgtg gctggttcga
     6781 ctggtagtgg gaagtcagta gcaattaatg ggattatcac aagtatatta atgcgtgcta
     6841 agccccatga agtaaaactg atgatgatcg atccgaaaat ggttgaattg aatatgtaca
     6901 acggcatacc tcatctgttg acgccggtcg tgacgaaccc tagaaaagca gcgcaagcct
     6961 tacaaaaagt agtacaagaa atggaagaac gatatgaaaa attcgcggca accggagtaa
     7021 gaaatatttc tggttacaat gaatttgttc aaccgaaaaa cttggaaaac ggaacgaaac
     7081 atccaacctt accattcatc gtagtgatcg tagatgaatt agctgatttg atgatggtag
     7141 ccagcaatga agttgaagat gcgattattc gtttagcgca aatggctcgg gcagcgggga
     7201 ttcatatgat cctagctact caacgtccaa gtgtggatgt tatcacagga atcatcaaag
     7261 caaatgtacc ttccagaatg gcatttgcgg tatcaagcgg tacagattct cggacgatca
     7321 ttgattctaa tggggcagaa aagctcttag ggcgaggaga tatgctattc ttgccaatgg
     7381 gtgagaataa accgatccgt gtgcaaggag cattcatttc tgaccacgaa gtagaacggg
     7441 tcgttcaatt tgttacagat cagcaagaag ctcattatga agagaaaatg atgccgacag
     7501 atgaagttga aacgacaggt gctccagaac agccacaaga tgagctgttt gaagaagcaa
     7561 aagcacttgt cgttgaaatg caaacggcaa gtatttccct tctccaaaga agatttcgga
     7621 tcggttacaa ccgagcagca cgtttagtag atgaactgga agctcatgga gttgttggcc
     7681 cgtcagaagg aagcaagcct cggaaagtat tcattgagca ggaagaaaca tcagaaacgt
     7741 tgccggacga taatgacatg taaaacttgt gtgatgaagg gttgaaaaac gaataaccaa
     7801 taaaaagaca aggcatgatg ataccaaaag aaaaaatggt ttttttccat cttttctaat
     7861 acggtatgat gtcttgtctt tttagttttt gtgagattaa agttctattc gatttatttg
     7921 tgaagtattg cattaaggaa atgaatcatg tatagtatgt agcgaaactt tgagaaaaag
     7981 agggaaaata ctttggaaaa acagtccatt tatggcttga cgaatgaaga attaatcaat
     8041 tggtttatag aaaacggcga gaaaaaattc cgagctgccc aagtttggga atggttgtat
     8101 caaaaacgtg taagtaattt cacagaaatg acgaatctat cgaaacaatt gatcgaaaaa
     8161 ttatcggagc attttatcat caatcctcta aaacagatgg tcgtccaaga agcttcggat
     8221 ggtacagtaa aatatttgtt tgaactccct gataaaaaca tgattgagac tgtactgatg
     8281 agacaagaat atggcttgtc agtttgtgtg acgacacaag taggatgtaa tatcggctgt
     8341 acgttttgtg caagcgggct gctcaaaaag aaccgtgatc tgactgctgg agaaattgtt
     8401 gcacagatca tgatggtcca acattatttt gatgagcgca atcttggcga acgcgtttca
     8461 catgtcgttg taatggggat cggtgagcca tttgataatt acgacaatgt aatggacttt
     8521 ttgcatatca tcaatgatgc caaaggattg gcaattggtg ctcggcacat tacagtttcc
     8581 actagtggat tagcacacaa aatcaaggaa ttcgctaata acggcttgca agtcaatctg
     8641 gctatttcct tgcacgcgcc gaataatgag gtgcgaacat cgatcatgcg gatcaaccga
     8701 agtttcccaa ttgagaaatt gatggaagct gtggatgagt atttagagaa aacaaaccgt
     8761 cgaatcacgt ttgaatatat catgttgaat caagtaaatg atagaccaga gcatgcgcaa
     8821 caattagcag atctattaaa agataagaaa aaattagcat atgtcaactt gattccatat
     8881 aatccagtca gtgaacatga tcaatattct cgcagtccaa aagctgatgt attgagattt
     8941 tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac gtaaagaaca tggtacagat
     9001 attgatgcag cttgcggaca attgcgaagc aagcaaatga aaaaaacagt tgccaaataa
     9061 tcgtatccta ctcgtttttt caattaccat aaaaggagca gttttcttaa ttaaggaact
     9121 gttcaactta aataagagaa aagattctat agcgaaagct ataaagcttt ttttgacaag
     9181 aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg acagcctgct tgatgggggt
     9241 tttagcaatt atttaactga ttttcttata tccttgctgg ctttcttgtg tagcatgata
     9301 agtttctacg tcaagaatgg cctgtttaaa tttttctcgg gtgatttcat aaggcacatg
     9361 tttaatatca tttgttgcca tggctttatc taagattgct tctaaatcgg tcgtgacatt
     9421 gagattcatg tcggttaacg atactggaag ttggttcttt ttcataaaca catagatttt
     9481 atcaaacaaa tcgaactgct gatccatcat caataaggtc agtacaccat aactgacaga
     9541 tgctccgtga aggtatccct ccattttttc tagaacagtc gtaccgtaat agaatgagtg
     9601 tgccatagca gaattatagt tattgttaac taaaacagaa accaatccgg tagtaacaat
     9661 gatatccgaa acgacttgtt caattgcata tgagggacga tcgtcggcac tatctttcaa
     9721 tgcttgcgta ccataagtca agagacgatc aatgcacatt tttccgattt ggattcctaa
     9781 tctatccgtg tagcctagat catcgccacg agcagaaaaa gtagattcga cttctttgga
     9841 taaagcatcg ccaatacctg cccataagta tttatcaggt gcttcggcaa taattgctgt
     9901 atcaatgaag gtgtgtacag gtggttttga aggaaagaag agtccgtcca ttacgccttc
     9961 ttcgttatag atgacacata ccgcagtgac gggcgaacag ttcgaaccaa tagtgggaaa
    10021 ggtgaagact ggtttagcta gtttttcacc aatgactttt acagtatcgc aagcacggcc
    10081 accaccgact gcaaacagga cgtctgcttt ttggacactt tcatgctgga tcaactgttc
    10141 aatatttcca taagttgaat tacccccgta ccagagactg gcgacaacct ctatttcctg
    10201 tgtcaaagct acttttattt tgttttctgc ctttgaaagt gcagtcttcc ctccaatcag
    10261 cactactttt gtcccatatt ctttgacgat tccatttgct ttttcatacg catctgttcc
    10321 aatggtataa tttggtaaga aaacactttg actcatattc atttccttct ttcttcgttg
    10381 aaacgggtta aaattttaaa gagtgatcga tctgactgcg gctgtagatg gagtagaggt
    10441 gaacctaaga caggataagt gatgaataag gtggcatgaa caccttgaaa tcatcaataa
    10501 gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga caataatgaa tttttgttcc
    10561 tcttagtatt tctaccgatt ccctttgctt ttttgtaatt atctaaaaat tctaaaaatt
    10621 aagattatta tatgaaaaca ggttttattt gtcaattcat aattggtttt ttttaaagca
    10681 aaagataatc tatatcatga tgaacaaaca gagttttttc ctccaattga tggctttcct
    10741 gatctttcct attttgaata aagtgtttct gtataatttt tttattttat aagtaagata
    10801 aataatgaaa gaatagagat actgattggt agctaaagat ttttgagcga gaacatttcg
    10861 ttttttcaaa aggactgtta gaataagcaa gaacaagggg gaagacgtat gataatcagt
    10921 gaatttgacc gtaataatcc agtattgaaa gatcagcttt ctgatttact gagactgact
    10981 tggccggaag aatatggaga cagctcggca gaagaagtag aagaaatgat gaatccagaa
    11041 cgaatcgcgg tagcagcggt agaccaagat gagttagtag gatttattgg tgcaatccct
    11101 caatacggta tcacaggttg ggaattgcat ccattagttg tagaaagctc ccgacgaaag
    11161 aaccaaatag gtactcgatt agtcaattac ttagaaaaag aagtagcttc cagaggagga
    11221 atcacgattt atttaggtac ggatgattta gaccatggaa caacgttaag tcaaacggac
    11281 ctgtatgagc atacatttga taaagtggct tccatccaga accttcgtga acatccgtat
    11341 gaattctatg aaaaattagg ttataaaatc gtaggtgtct taccaaatgc aaatggctgg
    11401 gacaaaccgg atatttggat ggcaaaaacg attattcctc gaccaaattc tcaataataa
    11461 aaagaggttg tgacagaagt aatcagcttc aagaaataag aaggaattta cgaaaattac
    11521 ttcttgaatt tttgtgaaat tccaacttat ttccgaagaa gctacttttg gaacaccgtg
    11581 tacc
//
LOCUS       DADQCX010000085        11511 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.086, whole genome shotgun sequence.
ACCESSION   DADQCX010000085 DADQCX010000000
VERSION     DADQCX010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.086"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(191..391)
                     /locus_tag="J8R83_002183"
     CDS             complement(191..391)
                     /locus_tag="J8R83_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575300.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            complement(476..847)
                     /locus_tag="J8R83_002184"
     CDS             complement(476..847)
                     /locus_tag="J8R83_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575301.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            complement(898..2526)
                     /locus_tag="J8R83_002185"
     CDS             complement(898..2526)
                     /locus_tag="J8R83_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575302.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            complement(2546..2749)
                     /locus_tag="J8R83_002186"
     CDS             complement(2546..2749)
                     /locus_tag="J8R83_002186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575303.1"
                     /translation="MSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNA
                     YIARLKRFIDKYKENSDKFSKDK"
     gene            complement(2750..3439)
                     /locus_tag="J8R83_002187"
     CDS             complement(2750..3439)
                     /locus_tag="J8R83_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575304.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            complement(3694..4014)
                     /locus_tag="J8R83_002188"
     CDS             complement(3694..4014)
                     /locus_tag="J8R83_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575305.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            complement(4047..5165)
                     /locus_tag="J8R83_002189"
     CDS             complement(4047..5165)
                     /locus_tag="J8R83_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575306.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLRTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            complement(5194..5988)
                     /locus_tag="J8R83_002190"
     CDS             complement(5194..5988)
                     /locus_tag="J8R83_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575307.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSKRLRITVEYGTNESATELKQRYLDTRREASKKYNDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            complement(6041..6394)
                     /locus_tag="J8R83_002191"
     CDS             complement(6041..6394)
                     /locus_tag="J8R83_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575308.1"
                     /translation="MISENLSYENNKHLVKENKKVEDYKNMYIEMKKSPLCIQYKNDN
                     WKQVVEFVKPHSIRRVRRGKKKSELVNSGRAVIRVITKDYPVEYGDYILRLSYHAFVV
                     LKEEHFNEFFNLKSK"
     gene            complement(6496..6753)
                     /locus_tag="J8R83_002192"
     CDS             complement(6496..6753)
                     /locus_tag="J8R83_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575309.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGLRSYTTSEKDK"
     gene            complement(6756..6980)
                     /locus_tag="J8R83_002193"
     CDS             complement(6756..6980)
                     /locus_tag="J8R83_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575310.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            complement(7153..8196)
                     /locus_tag="J8R83_002194"
     CDS             complement(7153..8196)
                     /locus_tag="J8R83_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAZ9575311.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            complement(8375..8629)
                     /locus_tag="J8R83_002195"
     CDS             complement(8375..8629)
                     /locus_tag="J8R83_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3034 family protein"
                     /protein_id="HAZ9575312.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDEFLPRYSSL"
     gene            complement(8814..9029)
                     /locus_tag="J8R83_002196"
     CDS             complement(8814..9029)
                     /locus_tag="J8R83_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575313.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            complement(9081..9995)
                     /locus_tag="J8R83_002197"
     CDS             complement(9081..9995)
                     /locus_tag="J8R83_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575314.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            complement(9995..10894)
                     /locus_tag="J8R83_002198"
     CDS             complement(9995..10894)
                     /locus_tag="J8R83_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAZ9575315.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            complement(10894..11481)
                     /locus_tag="J8R83_002199"
     CDS             complement(10894..11481)
                     /locus_tag="J8R83_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575316.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
BASE COUNT         3277 a         2376 c         1403 g         4455 t
ORIGIN      
        1 agttattgtt gtcaatttta gcacctcatt aatgtttata aacatataaa agatcataaa
       61 tacgtttaat tgttaagctc atattcacat gactgtccaa atgaaatatc ttatctttat
      121 tagaaatttc actcataaca cgataatata gatcatgatt caagtatcgg aatttcgacc
      181 tcaattgctt ttagaattgt accgtatcca gtaaattctt acgccagtcc atcactaatt
      241 tttcaaattc atcttcatca aaactaaatt ctaatccttc ttttttaaac agtaactttc
      301 tatctataca tctcgagaaa taattgtatt tatattcttt aagctcaata tctgttttat
      361 tatctttatc ccatgcaatt ctttttaaca tattaccact taatccttca tgtaataact
      421 gcttttttat ttgaataggt gtatacaagt tattaaagta aattgctgaa cctatttata
      481 tcggaattaa cagtccaaga gagaccttgg ctattaactc agattcaact atgaaaatat
      541 aaaaaaacca aataaatgaa gggattaacc aagcaaaaat ttctaatatc acattaaatc
      601 ttttcatttt tccaaaacta ctaagacttg atactaattc aatcaaaagc ttatcgctac
      661 ttgctgattc atcatattta gttcctagat tatctaaact tagcatataa gaaatttttt
      721 cctgatctgt tagttttgaa aatgaacttt cttttaaact ttggattata caatcagcac
      781 taaatatttc gtttaataaa gcagttttct tttctaattc cttagaagat aaagttagtt
      841 ctctcatagt gacttaccta ctttccaaat tttgtgtcct atttatcact tctctcttta
      901 tataagtgat aaaagatcgt aaatacgttt aattgttaag ttcatattca catgattatc
      961 caaataaaat atcttatctt tattagaaat ttcactcata acacgataat atagaccatg
     1021 attcaagtaa tctgtatata gaaaaatcgc atcacacgta ttcaaatttt taagtatctt
     1081 tccattattt tcgcttacat caaacatttt aatatttggt aatagttcag ttaatttatt
     1141 ttgaaaattt acatgtcctc ccactaaaag aatgttttta tgttttagat aagctatcat
     1201 ttcagacagt gaaggctctt cagttttacc atttaatgat tgtctatgtt cttgctcctg
     1261 caattgcttt aatactttat tttcaaacct cagctgttca agttcttttc tgattccttt
     1321 taattcttta atctcttgct tcaaaagttc ctcttctttt tttgccgatt tgactaaaga
     1381 ttctaaccga ccgttttctt tactcgcaat acttaattct tttcttaatt tgattacttc
     1441 agatttgttt tcttttctaa tacttgcaat ttgttttgct atttcataat cagaattcag
     1501 gatcaattct tccttagcat ttttaaacaa ccgagttaaa acgaactgat ataacaaact
     1561 ataaaaaact agcaaatagt caatttgtcg gtactcggta ttctgatcaa ttgcatatag
     1621 agagattaaa acgaaataca caatatcatt cagctcgcta cccttgatct caaaattatt
     1681 gactaagtaa ctatcaatac ccatcaaatc tgcaaaatct ccatacaaag aaaaatatga
     1741 ttttgacaat atatctatat ctgaatcgtc aaacccattt actattttcc catcattgtt
     1801 agtagttgct aacgaagcaa tagtgacttt tgaattgggt tttacaaatc ctatacctaa
     1861 tagttctttc atctttttaa tttcaagttt gttatccttt tgttcggctt tatgctgttt
     1921 catattgtaa agcggataaa atgctgttcc gtaagcacct tttagtacgt tatctataaa
     1981 ataatcttca gaacctgttt tgaatagaaa gttaatcgca gccaaattag ataacagctc
     2041 ttcagtgttg tgcatcaatt ttttatcatt taataaatta tccccaagat atttcattgc
     2101 ataataaggg tttgtttcgc tacttatttt taatattttt tgatagctat tcctcacgat
     2161 attaaccaaa atatctgtct gattaattga attacagtac aaagccactc ctaatgccat
     2221 ataaacattc aaatcatgtt ttgccgtacc gttgaataaa acgtcttcaa cttttgaatt
     2281 atctcgtcta tactttttga tcatattttt gatattttga tcattctctt ggtatatttt
     2341 tttcactcgt tccaatgcct tgggtttgtt ggaaacagca acagcgaagt ctagttcttt
     2401 gaaatcaata tttagtatct gtacctcatc acctagatta taatctctat ttacgctcgg
     2461 aaaactgctg aaatctaact gttttttacc tatttttggc gaaaatattc cttcgatttc
     2521 tggcaaatgt aatcacactc tctccttatt tatctttaga aaatttgtca ctattctcct
     2581 tatatttatc aataaacctt tttaatcgag caatataagc gttaaccctt ttaggttctt
     2641 cttttcgcca ttcatcgttt acgtgaccat tttcaaagaa agaagctaaa agagtttcca
     2701 cttcattaac catatctgcg atcgtatatt tttctgtacc ctcactcaat tattcatgaa
     2761 ctgttaagtg ttcatagcta agttcattca taattttgtt atagcgtttt cttgcttttt
     2821 caaattcttt ctgttcgtca aattccactt gattcttcat gttgttcttc ctctctgttt
     2881 gatatttttt cacttcttca agtttagcat ctagttccgc tttaacttct gtcacttctt
     2941 taagcgcttg ggataactta tgagacaatt tcgcataagt ttctctcttg tattcatttc
     3001 ctactcccaa ctcttcggag tagaactctt ctagtagtct tgcaaaatta acatttctcc
     3061 tgccagcata gttttttagc ttctcaaaat cagattgaaa gacagcaaca cttttgtaat
     3121 ccttttcacc ctcaaaatca aaagcatagt catactttcc tgaaatcaat tcatcaataa
     3181 ctgtagcaat atattgagag atagaaatat tatcttcact tctatgtcgc tctataagat
     3241 tatatatatc agggctgaca tgaaacgtac ttctcttttt tgtttgcctt tttctaactg
     3301 ttacgaccac ttttggaact tcactatctc cattgatctc tttgtatttt tcaataaata
     3361 attttctagc ttgttctcga ctttttgccg gaatttcatc tacaatttta tcttctaaat
     3421 aaatatagtg tgttctcata cattcgtcct ctatcttctt tactctcaat cttcatgatc
     3481 ttagttctta ccttgtttac tcttaaacct ttcaaaaaaa tctagtcaaa atcaaacttg
     3541 aaatcatcgt ctatcacaac acccttaact tcatctttag atttcccaaa ggaaccctta
     3601 ttttcaaatc ctttattttt gaatgatgat ggttatggaa aacttccttt gaaattctga
     3661 caagcataac tagtcagaac tgttttactt agattaagct ttcaaaagat actgatgaag
     3721 aactaagttc tcagtacctt cccattcttc aataaaaaat atttctcctt cttttaccca
     3781 ctctatagct aatttcttat aatcaaataa accatatgtg tttaagcctt tgtctttcat
     3841 taaactcaaa aactgatccc cttttaatct ttctgtatca tccatcagaa attcaactaa
     3901 atctttatcc atgcgtgcaa ctttttcgtc ttttagtgcc attgatttag catagtcagt
     3961 tgaatctttt agaataataa cacctacatt tccttccaca attttcttct tcatatttac
     4021 ctcctaccat cttttccaaa gagtatttag tcaaaatcaa actcgaaatc atcgtctatc
     4081 acaacaccct taacttcatc tttagatttc ccaaaggagc ccttattttc aaatcctttg
     4141 tttttaaatt ctaaagcttt ttcgacttct tctttggata ttgtatgaac ttttttctta
     4201 actactccaa gtttatacag ctcttcaaac tctggtactt cggatctgaa atacaatcca
     4261 tcagtacgaa tttttaatag cccatatgcg ctatgaacgt atttctgttc atatctaacc
     4321 atacgatctc taaatacgcc tgctaccatg gaggaatacg ctcgattata catactgtat
     4381 ttatcgaagg tgcttgtttc tccttctctt aatgattttt gtccgatagc accaaatact
     4441 ttcgttctaa gatttttata aagcttcaac gtatcaggat cagtttttaa tggctcgatt
     4501 ctttcaaaat attctttgag taatcctttt ttcgtcaaaa atgtgtggct atctaggact
     4561 tccatctctt taatatcata ataatcaagg ataagtgtta gctcaatctc cgataaccaa
     4621 ataggctcat tagctgtttt gggattttcg ccataatccg caaacatcga ctgtgatttt
     4681 ggattagcat atgttccttc tttggctgtt ccttcaaaat taaccaaaaa gaacatatac
     4741 gttcttaaat tttcatacgg tcttactttt ggtctattta tcgctctcaa aatagcttga
     4801 tctgtattat attttgcttt caaataagtg tttgacggca aaggataatt tctcatgatc
     4861 ctcgaatagg cttcgttgaa atcatattcg atcatctttg ctccttcctc aaacaaatcc
     4921 aagttataca tgctaccgga ggtactggct ctataggctg aacttggaac aaagaaaggt
     4981 gcatcttccg gcttatcata gcccaaaaaa tgtattcctg tttgcttgtt ctgacggtaa
     5041 atgtccatca aaagatattt gatcgtacta aaagaatcta attttcctct tgtcatccac
     5101 cctaatccga caagtctttt aattttattc tgcatttcag gtgtgtatat gctattgttt
     5161 cccatttatc tgctcatctc cggctttttt attctagacc ctatatttgt tcattacacc
     5221 acttatctcg tctacaaagg ctcccagatc gtgtgtaaag gcatcgtagt aatcttcaat
     5281 ctcactcgat tcagttctcc ggtttcttcc gtttttattt ctgaatagat acatctgcgt
     5341 ttctcttaaa tcccttgctt ttttcgcaag tgctaataaa tccgtaaaat tatcaataac
     5401 cataatgtca ttgatcataa aaccttcttc atgaccatac ttttcagcca tctcgataaa
     5461 atcattaaca tcgaacaact ccaataattc tgctttatat ttctctaaca atgtatttaa
     5521 atagcgattt ctcaattccc atgaactttc accagttccg tattcaacct tgatccctaa
     5581 attcttagtg tagccttttg ctgtgtatcg tccaatgaag tctcccttat tccgattgct
     5641 atcttcttcc ttgaaaaact cacgccaaat tccctttttc tttttaggaa tcagacctct
     5701 gctcttgaaa tcattatatt tttttgaagc ttcccttcgt gtatctaagt acctttgctt
     5761 cagctctgta gctgattcat tcgttccata ttcaacagtg atccttaatc gtttgctata
     5821 gccttttgct gtatatcgtc caacaaagtc accgccactt cgatcactac tgacttcctt
     5881 aacaaattct ctccatatac cttttttgtc tttcggtatt aatcctcgtc ttttcatatc
     5941 ttgatatttt tcagaagctt cttttagagt attctttttt gctaccatgt catcacctcg
     6001 caatttagtt aactttatac acgtctacaa aaaaatatga ttacttactt tttaaattga
     6061 aaaactcgtt gaaatgctct tctttcaaca caacaaaagc atgataactt aaccttaaaa
     6121 tataatctcc atattcaact ggataatctt tggttataac tctaattacc gctcttccgc
     6181 tatttacaag ttcacttttt ttcttccccc ttcgtactct tcgtatacta tgaggtttta
     6241 caaattcgac tacttgcttc caattatcat ttttatattg aatacacagt ggtgattttt
     6301 tcatttctat atacatgttc ttataatctt ctactttctt attttcttta actagatgtt
     6361 tattattctc ataagacaaa ttttcgctta tcatttaata tttcccttcc tttttttgca
     6421 ttatatttag caaacattca ccatttgaat ttgacatagc tttaagacag atattttatc
     6481 ttttcaaaca ttaagttatt tgtctttttc agaagtggta taggatcgaa gtccttcacg
     6541 tttcattatg tcttctgctt ttccaatgct gatccctttc caatcacgcc atcctacgct
     6601 tcccttattt tgacgatagg ctttaatagc tgattcggat atttgccatc ttgtagccag
     6661 ctcttttgcg gtgtacttat ttgagaaaag taacttctct atcagtgaaa tatcaatcat
     6721 tttattctca ctcctgaaat cttcattaat catctctagc tagctatatc ttcaatcaat
     6781 tctaatatgt cggataaacc atcaacagct tcttcaagtt gatcaacgga ttcttctgct
     6841 ttttcatatc tttctgatcc ctgtagattt ttaggtatat tttctttgta ctcttcttct
     6901 tgaattactt ctaactcatc ctttagctcg gaaagtcgct cgcttatttc ttctaacctt
     6961 tttcttcttc tttggttcat caaaatcacc tcttcgcata atctctacga ttttaatata
     7021 ccacttttgt gtactacatt caatattttt tgttatagat tcgtattaca aaaatttcct
     7081 ctaaaaaaat aagagcctat ttaccatttc agtaattaag ctcttatttc atttagttga
     7141 taattctatc aattaacgta cagcaaccgc cattccagtc acattaaatg ctctctcata
     7201 cgtgcttgca ttgatccatt ttgcgccaaa tacagggtca acaacatggt atgcaccatt
     7261 tctgaagcca tccacgagaa ctacatgtcc attccatact gcacgacccc aaggcatttg
     7321 tttgaactct ggcgtagcat agttataagt aatccaagtt acaaccggat taccattgcg
     7381 aatttcattc ttgattccat tcgttcctga accagtgata ttgacggcat taccgccaac
     7441 gttttttgcc catttaacta ctgggtcagc catcatgcct tgatacgttc cattaacgtt
     7501 atgacgccac tctcctgagt aaccatgata aggattattg tcattagctt ttggcatata
     7561 gtttacaaaa ctggttaagc tttgatttgt ggctacacct ttgtagtgta aaccttctaa
     7621 taaagaagct ccttcgcata acattgtatt tccttgccat acaacaggaa cgttcaacac
     7681 tttttcagtg cttggagcag gtgtaggatt tggtacgctg tttggcattg cataccagcc
     7741 tgtaccttca atcttccaac cttgtttact aattacgttc ttttcatttt gatctaacgt
     7801 gtagtgatgc caattcacgt atttgttata taaacgtgtt acaggaactc tatttgctcc
     7861 gttgtaggaa tagaacgcaa caccttcgta cgtccatcct gtgtgtgaaa tcttatctct
     7921 ttctccggca tcaactgtgt aaaaatgttc accgttatac cgattataca aacgataaac
     7981 aggagtacca cttgttggag cttgccatgc gacaccttcg taatgccatc cataacgttt
     8041 cagattgtct ctttctccaa cgcttctagt gtatagatgc tctccgctat tgggattata
     8101 catacgatac atggaaatag agctttctgc tgaaactgaa ggtgataata atactagccc
     8161 cattgtgaat agaattccta ctaaaaattt tttcatttga ttttacccct tttcattttt
     8221 tattgtcatt attgcatgaa aattattcgt aagattgcca attacataaa cgattgtttt
     8281 aagatcataa tcgttgttgt cttaaattca ttcctccttt ccaattcaag agtacctatc
     8341 aataatgaca catactcttg aatctttcgc caaatcataa acttgaatat cttggtaaga
     8401 attcatcacc catacgtttg ttttctctat ctatatggtt ctgtatacct acaacatcat
     8461 gagcgaaatt aacatcatca gaattcaaca aggcttttaa tcgcagatta aattcttggt
     8521 gggcaacgct taaatccatc tttaaagaaa tacgatcaaa aaacataatt cccatattat
     8581 ttgctcgttc aacaatttga aatatatcta ttagttcttc ttttttcata actgctcttc
     8641 ctttaacttg ttaatctaac ttgcttacaa atatatccta ccacatttgt gtactatctg
     8701 tcaatatttt ttgtgtataa atgtgtatta taaaacaaat aattttacac aaacaaaaaa
     8761 gagcctaact gctcttagca ataagctctc atcactgctc ctcgtgaatt tagtcagtac
     8821 aatgtatttg ccttttcttt gataaaatcc ttatacgaaa aattgttcaa ccaaaattgt
     8881 tttagcacta ccgaattttt gtttccatca ttcaactcca attgaccaaa tctgctgatc
     8941 atatcatcaa tttcatcaat tatctcttgt gccatcatgc cgtcttctag acgttctaat
     9001 acgtacaatt caaaaacatc ccttttcatt caaaatgccc ctttcaggtt accttttgcc
     9061 attttatggg ctaactccgc ctactcagct ttttttatat acctactgat atttgctttc
     9121 gtatttcttg gcataccacc tgcttgcagg taatgttcac gataataagc atctagctct
     9181 gaaacagctt tttctaatct attcgttgca ttcaacactg agcggtattc acgtttttcc
     9241 cttaatacac gtcttaaatg gttcatcgct gatatataag gcttatagta ttccaataca
     9301 gtatatcctc tagaaatata ggcaattgga tttctagctt catggatcaa ttctaaaata
     9361 tctgttggat caggcttatc cggcatctct tcttcgattt ccataatact gatcaagtag
     9421 tccaatccgg aatcatcgac tccataactt tcacaccatt cttttaggtt gttcaagtca
     9481 tgaataacat cttcaggatc aaactctcta aaagcagtga tcccttggct ataatatttt
     9541 atatattcca ttgccgattc aaaatcctct ggcggtatga aagcttcaat ttcttcttca
     9601 tcaatcgctt tcagcactat tccgatacct gagtttgaag gatattttct caatccttct
     9661 tcaattaaat cctcatctat tcgtcctttt tgaaacatca ccaataattg ttctaacagc
     9721 tgatctaaaa ccctgcgctc ttcattcagt tccattgcat ttttaacttc tttttcaccg
     9781 agttcaaagt aagctttgat caacttttct tgttcttttc gttcaactaa tttcttcttc
     9841 aagtcattca tattgagaat gaaatccatg tgattactct tttgctgatt gacaaaatca
     9901 tatctttgtt ccaaaacatc ccgatatttt tttagttctt cttgaattat ttcaaagcta
     9961 tcaagtacat gaagaatttt ttcattatta ttcatcagcc catctcctgt agtctcacgt
    10021 ttgttttcga cttttcaaaa gtattgtatt taaaagcaat taaccctaca accctgctat
    10081 ctttgatgcc tatttccttg ttaaaaattc cgtccaatgt tcctttgact aaattatcaa
    10141 tatccggctg tgaagtacgc atcagtgaat caagcttttt cttatctttt ctcacttggt
    10201 aaaaataatc tatctgagct ataaccccca taggagcatt cattaccttt ttcagttgat
    10261 catttaccaa atctttctct ttaagcgtat tcttgatatt ttccaaatag tcgttgtact
    10321 cttttggata gtaagtgata atcccatttc ctctaaattt agactttggt cttggcgttg
    10381 ctactggttt aaaatcaaat gtagcttccc atatatctcc gttcaatcct tcagaagtat
    10441 cccactcaaa ttctgaatat cgtttgatcc tcacaactgt ttttccttcg ttcgccacat
    10501 tatatttaaa agcaattaag cctgtgatat ggctatctcg tatagctgag atgttaaaaa
    10561 taccatccat agcacttttt actaaattat ctaaatctgg cgctgttgtc ttcataatgt
    10621 tatagacttt tttatagctt tttggtatct ggtagtaaaa gtccacttcc ataattgcgc
    10681 ccataggatc atttacaatc gagtaaaatt catcatctaa taaatcttga tcttcgataa
    10741 agctctttat ttttttcaaa taatcaagat actttttatc atagtaggtt gaaatccttt
    10801 tctctgctac gtcattagtt tcatcagcag cattccttct tgcacttggt cttggtgcag
    10861 atacaggttg gaacggtaaa gttacagtcc acattagtct tttttgatct ctttcaaata
    10921 gattttttta aaggtatcaa ggcttaaagg agctaccttt tgcatcttcc ggattttatt
    10981 tacttgttcc aattgtttca atagaccatc ttcttttcta aggtactcag gatttgttat
    11041 ttgtttattc cgatactcga ttaatgattg aagctctctt actgttaaaa catcctcaat
    11101 ttttgcttct ttactcgtta tcttttttag ataccctaat actgttggat aagatttgcc
    11161 gatcacttct gcgatttctt ttttattgta ctcaccaaat tttccaagca accagtcatt
    11221 catgatctta cttgatactt ttgggtatac aagaattgct ttttcaatgg aatgactgcc
    11281 attatttctg atcagttgac tatctttaca ctcaactgta acgccatcac ctaaatcaac
    11341 aacatattgc caaacgcctc ttcgattctt attaagagaa ataatcgttc cctctttatc
    11401 tctataatcc tttgataatt cacttactgt tgtaactctt tccccaatgc taaaatgtct
    11461 aatatcatta ttgttttcca cttattatcc ctccaatatt gctggttatc t
//
LOCUS       DADQCX010000086        11291 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.087, whole genome shotgun sequence.
ACCESSION   DADQCX010000086 DADQCX010000000
VERSION     DADQCX010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.087"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(3..2012)
                     /gene="metG"
                     /locus_tag="J8R83_002200"
     CDS             complement(3..2012)
                     /gene="metG"
                     /locus_tag="J8R83_002200"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAZ9575317.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            2280..2558
                     /locus_tag="J8R83_002201"
     CDS             2280..2558
                     /locus_tag="J8R83_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575318.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            2655..3476
                     /locus_tag="J8R83_002202"
     CDS             2655..3476
                     /locus_tag="J8R83_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAZ9575319.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(3761..4771)
                     /locus_tag="J8R83_002203"
     CDS             complement(3761..4771)
                     /locus_tag="J8R83_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9575320.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(4783..5736)
                     /locus_tag="J8R83_002204"
     CDS             complement(4783..5736)
                     /locus_tag="J8R83_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9575321.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            complement(5726..6796)
                     /locus_tag="J8R83_002205"
     CDS             complement(5726..6796)
                     /locus_tag="J8R83_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575322.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            complement(6802..7845)
                     /locus_tag="J8R83_002206"
     CDS             complement(6802..7845)
                     /locus_tag="J8R83_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575323.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            complement(7846..8787)
                     /locus_tag="J8R83_002207"
     CDS             complement(7846..8787)
                     /locus_tag="J8R83_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575324.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            8871..9218
                     /locus_tag="J8R83_002208"
     CDS             8871..9218
                     /locus_tag="J8R83_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAZ9575325.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            complement(9288..10949)
                     /locus_tag="J8R83_002209"
     CDS             complement(9288..10949)
                     /locus_tag="J8R83_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9575326.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
BASE COUNT         3188 a         2295 c         2054 g         3754 t
ORIGIN      
        1 ttctatgcga tttctgagcc atttggcatg gattttggtg cttcgattac ttgtaaagag
       61 ccatctggtg cttctgcaga aaggatcatt ccttgactga tttgtccacg catctttcgt
      121 ggtttcagat ttgctacaat gacgactttt ttcccgatca attcgcttgg atcaggataa
      181 aattcagcga ttcctgacaa gatttgacgg tcttggctgt ctccagcatc tagtcggaat
      241 tgcagcaact tatctgcccc ttctactttt tgacagttga tgacttctgc tacttttagt
      301 tctacttttt caaatacatc aaatttgatt tgtttttctt tcgttgaaac aagttctgtt
      361 tcttctggat cccatttgac tgtatcttcg tttgtttgag taccttcaga cattttttct
      421 tgaataaaag caacttcttc ttccatatct aaacgtggga agattggtgt accttttgca
      481 actacttttg ttcctgaagg aaattcgcca aagtgtaatc cttcaagatt cattgtttca
      541 gagtccaatc ctagttgatt gaagatcttc tctggcgttt ctgtcatgat tggctgaagt
      601 aatatcgctg cgatacgcaa agattcagct aaatggatca tgacactatt caattcagct
      661 ttcttttctt cgtcttttgc taatacccat ggttctgttt catcaatgta tttgtttgca
      721 cgagaaatca gcacccagat ttcagccaat gctgtattga attccatttt ttccattgca
      781 tcatggtaac gtccgacaac gttagcagcc gtcgtagaca gttcactatc aaatggagtg
      841 acaagtgagg catagtcagg aacgagtcca tcacaatatt tgttgatcat agcaatcgtt
      901 cgattcaata agttccctag atcatttgcc agatcataat tgacacggga aacaaaatct
      961 tctggcgtaa agacaccatc tgacccaaac ggaacagcac gaagcaaata ataacggagt
     1021 gcatctaaac cataacgttc cacaagcatt tcaggataaa cgacatttcc ttttgattta
     1081 gacatttttc cgtctttcat caatagccag ccatgcccaa atactttttt aggtagaggc
     1141 aaatcaaggg ccatcagcat gattggccaa tagatcgtat gaaagcgaac gatttcttta
     1201 ccgaccatct gaacatctgc aggccagtat ttttcgaata gactttcatc ttcggagcca
     1261 tatcctagtg cagtaatata attggataat gcatcgatcc atacatacac cacatgtttc
     1321 ggatcactct tgactggtac tccccaagta aaagttgttc gtgaaactgc aagatcctct
     1381 aatcctggtt tgataaagtt gttgatcatt tcgtttttac gagattctgg ctggatgaat
     1441 tcgggatgtt cttcatagta ttccaataga cggtctgcgt atttgctcat gcggaagaag
     1501 tatgattctt cttttaccaa ttctacttcg tgtccacttg gcgctttacc accgatcacg
     1561 ttaccttcgt catctttgta cacttctgca agttgtgttt ctgtaaagaa ttcttcgtca
     1621 gaaacagagt accagccttc atattcacct aagtaaatat ctccctgttc taataaacga
     1681 tcaaatattt tttgaacagc tgctttatgg taatcatctg tcgtgcgaat gaatttatca
     1741 taactgatat caagcgtttt ccataatttc ttgacatcag ccgccatttt atctacatat
     1801 tcttgcggtt ttacacctag ttcttctgct tttgtttcga ttttttgacc atgttcatcc
     1861 actccagtga gataaaacac atcaaagccc atcaaccgtt tataacgagc aattgcgtca
     1921 catgcaatcg tagtatacga gttgccgata tgaagtttgc cgcttggata atagattggc
     1981 gtagtgatat aaaaagtttc cttttctgcc acggggctct tcctccttta tcgcatgatg
     2041 cgaattcgtt tccttgctag tataccataa aaaaagcatg ctgttagctt tttttcaaaa
     2101 tgaaaaagac tggataaacg acttctatct acgttcaatc tatcctttaa aaggatgaat
     2161 aggttgaata aatgcgggtt tttgttttgt ttcatatcta ctaaaaaacg gctttttatt
     2221 tctcccctca cacgtggtat aataaagact atctatctta gtaagggact ggaacaatca
     2281 tgcagaagaa acatcttttt tttacactta gtattgcttt tctttcatta gcacatttaa
     2341 tattcagcta tttttatatt cgtatgtatg gttattttaa cctccatggg catttgaaca
     2401 gttttatgac agcagcttgg attttgcgtt ttatcattga cgtatatatc gttatttgtg
     2461 gcttctttgc cattcgtgaa gagcggtata aagtattgcc gttttatctg cttttctttt
     2521 tattcaatct catacttcca tttatttttc atatttaaat gataacctag atttttcaag
     2581 taaatccttg gttttttttc agagtctgct acaataaggt aaaaagtact tttactgtca
     2641 atggaggtgg tcagatgaac cgttttgctt ctaaagaaga agaaaaatta tattatgaac
     2701 ataaagcaag tgaagaagaa tttcttaact ggtatcaaaa acaggaacgt ccagaatatg
     2761 acaagccctc tttgactgtc gatatcgtac tgatgtgcta taacaaagaa gaagatcagc
     2821 tgaaagtttt gttgatccaa agaaaagggc atccttatcg aaattcatgg gcattgcctg
     2881 gtggctttgt ccaaaaggat gagtcaactg gagaaagcgt cttaagagaa acaaaggaag
     2941 aaactggtgt ggttatttca aaagaaaata ttgagcaact gcatacattc agtacgccta
     3001 atcgagatcc gcgaggctgg gtcgtcacag tcagctactt agcctttatt ggagaagaac
     3061 cgctaatcgc cggagatgat gccaaggaag tacgctggtt cacactagaa cgtcatagta
     3121 acaagatcca tttatctagc ggagaagtgg ctatctcgct tgatttagtc actggagagt
     3181 cttctggcaa agatactttg gcttttgacc atagtcaaat catcttgaaa gcattcaacc
     3241 gtgtagtcaa taaaatggaa cacgagccgc aagttctaca agttttaggt aaagatttca
     3301 cgattacgga agctcgaaaa gtatttgcta aattcttagg gatcgattat aaaacgatcg
     3361 atcattccaa ttttaagaaa gctatgctcc aatatttcga tgagatcggt gaacgtcctg
     3421 taggaatcgg ccgtccttca aaaatctatc agctcaagcc ggggcaccat gaataaggtt
     3481 gtgagcaaaa gattcagacc taatcattca agaaaaaacg caaaaacaac tctttgtgag
     3541 ttacgttttt tgtttcagaa ttttgatgta ttcgtaaact ttctgaataa aaaattaaca
     3601 atagcagaaa aagctcgtac gaactttttc tgctattgtt ttattggttt gtcataatta
     3661 gtgagctttt cttcaaaaga aaaattccta gaaacaaaag tcattaagac tttttattaa
     3721 caaggctaac cctaacgctc ctatcagttt cattcatttt ttatcccttg ataaccgaat
     3781 gtctgcccat tttttctact acttggctct ttcttacgga attgctttct tctgctccgt
     3841 cggtattgat caaaagaaat tttttattat accattggga cttataacgc aattttgtta
     3901 ttaatttatg ccagtcgtga atagaaaaat cagcatgtgc ctcttctttt ggaaaagatt
     3961 ctacaaataa gtagtcatat tgtttgacca atttcccaga taattgttca agataatctt
     4021 ctcgctggtt cttttgtttc agataaagat ccattacttt tctcttttgt ttctgataat
     4081 tgcttgcctg atctaacctg atctttctat ggtgagcgga gcggactttc acattcaatt
     4141 tccgctgtgc atgttgcagc ttttcttctg tctggtgaaa ttttggtaaa gttacttcta
     4201 gaggtcgaga tgtttggatc aatgtcttcg gatgataggc gatcccgatc catttagcta
     4261 aagattcttt ttttactggc gaaacatcac aaagtagtgc gacataaaat tcttcattat
     4321 atcgagcaga aatcgtagcg gagcgaatcg atccttcaac tggccgatgc tgatttatct
     4381 tgattagttc tttttgtttt ggtaacttta agtagccatt ttccagatag atcgtacggg
     4441 tttggttgtt ggtcgtataa gattgccaca tacttttttt cgttttaagc tttgggaagc
     4501 tggcacgtcc cttgaaataa ttgcgaaaag cccgatccaa attaagctgt gcatttgcta
     4561 aagcaagact gtctacttct tttaagaatg ggtattcttt ttttaatgta gcgggtgtga
     4621 gcgaaaaatt ggctactcct gtttgttgcc aacttttctg ccgctttttc agcaaatggt
     4681 tataggtaaa tcgagcacat ccaaaagtac gaatcaattg ctgtttttgt tcttctgtcg
     4741 gatacatacg gaatttaaaa gcttttagca tctatgtccc tcctagttag caaccagaag
     4801 agattccttt tgtcgtttta gtttttttgc gtaatatggg acttcctgct cagttgcata
     4861 gacaaaatgt tctggtgcga tttcacgaag ttgacgtact tgtccgtcat ctggttcagg
     4921 ttgatatttg attcttctgc gttttctctc atggtctgga tctggtagag gaatagcaga
     4981 taacaaactt tctgtataag gatgaacacc gtgattatag atttcatcac ttgttcccat
     5041 ctctaataac aagccgttat gcattacacc gattcggtca ctaatatgtt taaccatcga
     5101 caaatcatgt gcaataaata gataggtcaa ttgatgttct ttttggagat cttgcaacaa
     5161 attgaccact tgggcttgga tcgacacatc tagtgcagaa attggttcat cacaaatgat
     5221 aaaacgcggt tttactgcca atgctcgtgc aataccaata cgctggcgtt gcccacctga
     5281 aaattcatga ggataacgag taccgtggct tggattcaat ccaacagttc tcaatagatc
     5341 atcgactttt tttgcacgct cttcagatga tttagctagt ccattaacat caattccttc
     5401 ggcaatgata tctctgactt tcatacgagg attcaacgaa gcgtatggat cttgaaagat
     5461 catctgaaca tcatgccgga atttcgtcaa acctttttta tctttgatct tcgttatatc
     5521 ttgaccgtcg aataatatct caccatcagt aggttcattc aagcgaatga tcgtacggcc
     5581 agtagtggat tttccgcttc cagattctcc aactaaaccg aatgtttctc cttcataaat
     5641 gtgaaagctg atgtcattta cagcatgtac ttcattcttt tttcctacat tgaaatactg
     5701 tttcaatcct ttaacttcaa gtagtttatt tggcatcagc aattcctcct tgaccgtaag
     5761 tatgtttttg tttctcttta aagatagccc agcgacgttg gatttcttct ggcggtgtca
     5821 ctttgggtgc ctgcggagca agtagccaag ttgctgcctt gtgtgttttt gatagttcaa
     5881 aaaatggtgg ttcttgttct gcatcgattt tcatcgcgaa ttcatttctt ggatagaatg
     5941 cgtctccttt tggcgggttc aataaatccg gtggagaacc aggaatagca tacaatcgat
     6001 cgttcgcact atctaatgtc ggcattgaac caagcagtcc ccaagtatag ggatgttgcg
     6061 ggttgtagaa aatttcttcc gatgttccaa cttcaacgat tcttcctcca tacatgacag
     6121 cgacacgatc agcgacattc gctactacac caaggtcatg agtgataaag ataattgatg
     6181 tatcgatttt tgtctgaatt tctttcagca gctccaaaat ctgtgcttga atagtcacat
     6241 caagcgctgt tgtaggttca tcagcaatca ggatttccgg ataacatacc agtgcaatcg
     6301 cgatcacgat ccgttgacgc tgacctcctg agaactgatg cggataactg ttgatacgtt
     6361 tctcagcttc gggtattcca actaatttaa gcaattctaa tgcagctttt tgtccctctt
     6421 tttttgaaac tttattatgc tttctaaggg actcagcgac ttgcttccca atgggcatcg
     6481 tcggatctaa agaggtcatt ggatcttgga aaatcatcgc tatttcttta ccacggattt
     6541 tttgcatctc tctttctgat tttccaacga tatcgttacc tttaaagagg atttgaccag
     6601 catctatatt ggcgttgctt gacagcaagc gcatgatgct tctggtcgtc actgattttc
     6661 cacttccaga ttccccaacg atcgccaatg tttctccttt attcaaatga aaattgacac
     6721 cgcgaatcgc tcgtaccttt ccagcatacg tatcaaaaga gatttctaag tctttcactt
     6781 ctaaaatttt cgtcatcgtc ttcactcttt cattttagga tcaaaggcat cacgcaatcc
     6841 atcagcaagt aagttaaagc caatcatgat aaccgataaa gttactgccg gaatccataa
     6901 tagataaggc agatacagga atgtcttgta cccttcgctc aacatcgttc ctaatgaagc
     6961 tgacggaggc gtaagaccta aaccgataaa gcttaaaaag gcttcgaaga aaatagcaga
     7021 tggaatacta aacatcattt gaataataat gacactagag atattcggca aaatatgttt
     7081 gaatgcaatt ttcattcttg attcacctaa tgtcaatcca gctaaaacat attcttgatc
     7141 ttttaatttc attgtttgtg cacgaacgat acgtgccatt ggtatccagt ttgtgatggc
     7201 catagcagcc acgattgaaa aaattcctgg ttcaaaaacg accaacatca aaatcatgac
     7261 aacgaggttt ggaattcctg ataagatttc caaaaaacgt tgcatcacgt tatcgacacg
     7321 tccgcctaac aaaccagaaa ccaacccgta agctacacca atcgttacat ctagtaatgc
     7381 agcaataaat gcgatcagca acgagattct cattcccata aataagcggc ttaatacatc
     7441 acgtcccaaa ccgtctgttc ctaaaaagaa atttacgttt gaagggacgt ttgcttgagc
     7501 atatttatca acaagttcac caccaaccat tgcttttcca ttcaatccat cgatattgat
     7561 tcccggaata cgaggaggca aattgatata agccacgttt tgggcagttg gatcatgagg
     7621 agaaacaaag attgtgatca cagagatcaa aatgatgacc aatagtaaaa ccattgaaat
     7681 aacggcagct ttgtttttct ttaaacggcg ccatgaatct tggataaaat tcaaagaagg
     7741 tgcagtaatc tgttcacgtt cttcttcggt atttttttgt aatggaagaa attcatccgc
     7801 agggatatct gcaactgttt cataacgctt tggtatcatt tccatttatc ctcggctccc
     7861 ttctgaaaca cgaattcttg gatcaactag accgtacaat agatccacga tcaaaataac
     7921 aaaaatcagc ataaatgagt aaaggatcgt tacagccatg atcgtaggat aatcatttgt
     7981 tgtgattgac ttaacgaatt gttccccgat accaggaata gcaaagatat tttctaccac
     8041 cagtgatccg gtcatcaatg ctacagctaa cggtcctaat aaagtcatca atggaatcaa
     8101 actatttcga agaccatgtt taaaggcgat ttcccaacgg ctcaatcctt ttgcttttgc
     8161 taattccaca taatcactat gcagtacttc caccatttcc gtacggataa accgagcaga
     8221 gtcagcaagc ggcgacatgg ccaacgcaat tgttggtaag attgtgtaca caaagccatc
     8281 ccattttgcg attggcaaaa cttgtaattt gattgcaaag atatattgta ataaaacagc
     8341 aaatacaaag tttggaatgg aacgacctaa tatcgctacg agtgtagaag atgtatctgc
     8401 ccatgtattt tgcttcatgg cagagatcgt tcctaaaatc gtccctagga ctgttccaaa
     8461 gataattgcc tgtaacccta actgcaagga tggtccgatt cttccagcta acaaatgtgc
     8521 gactggctgg tttttaaatt ggaaggaaat tccaaaatct ccttgaagca aattagaaag
     8581 ataaatccca tattgtacga taactggttt atccaaaccg acttgtttat ttagcatctc
     8641 gattgtttca ggactcaaac gttcctgatt cgtatatggc gtgcccggca gcaattgcat
     8701 caagaaaaag gtgattgttg caattaacca aagcgtgatg atcatgaaaa agacacgttt
     8761 taatacatat ttgatataac tattcactaa tgtttccccc tagcttttga cttctgacag
     8821 atgtttcgct acattattag ataatgaacc aaaaataaag gagcaatcaa atgaaaaaaa
     8881 aatctatccc ctacgcagta gcttttctac tgattctggt tattttaata aaaaatctca
     8941 tcaaccattc ctttacactc attcaattat ctaatgatct attcttatgg tcattgccgt
     9001 ttctgattat cggcggtttt ttatgggtct tttcttcggg tttcttcgat cattttcagc
     9061 gatcggtcca tcttgcacga acaaggaacc gaaagaaaaa accagaattt tcctcgctct
     9121 cgtctgccag ctacggtatg tacagctttt ggctgatcat tgccggaata ctaattgctc
     9181 tttctgctat tttcatgctt ttttctttgt taggataagt gaatatgaga acgaggttgc
     9241 gacatttgcc gcagcctcgt tttttctcat gctcacggta ttaacgatta ttcttcaacg
     9301 tatgtccatt tgtaatccca tgaagcgcct gccgcatggt gaacgatacc tttgattttt
     9361 tcattcacta ggtgaccttc tgctttttgg tacaccggaa cgacacccat atcatcagag
     9421 atgatcttga ttgctttttg gaaatcatcc caacgggctt gttcatcgcc agcgtctgtt
     9481 gatgaagctg ctttaactgc ttcgtcatat tctgcattgc tccagcgacc acggttgtat
     9541 gaattacctg tgacaaacaa atcagtaaag ctgcttgggt ctgcatagtc agcagcccat
     9601 ccgcctagta ctgcgtcaaa atcacccgaa gttgagcggt caagacgtac agagaatgga
     9661 acaggtgttg gtttgactgt tacgccatcc aagttttctt ggattgagtt ttgaacatat
     9721 tcgattactt ttttcgatga atcatcatca gaagccatca aatcaaattc taaagaatca
     9781 acgcccaatt cttttttcgc tttttcccaa tattcttttg ctttatcttt gtcataagaa
     9841 actaattttc cagcttcttt tgcaaagtct tcgttcgttg ttggactttt taccatatct
     9901 gatgggatca atcctgtaga gacaactgat ccgtcaccta gtacttgttt tactaaagct
     9961 tcacgatcga tagaataaga aatagctttt cttaggttca cattgttgaa tggtgaattc
    10021 ttttcacgtt gattgaattc gatatagctt gtccgcgctt ctttaacaga agtataagct
    10081 ggatcgtttg cgttttgctg tgctaactca ccagacaaga tcacgtcatc tgcttggcca
    10141 tctttgaata agttcaatgc agtagaagat tcttttacta cactgacttt gatttcagaa
    10201 agttttactg tatctttgtc ccagtaatga tcatttttct tataagtcca ttctgtatct
    10261 gttcctggtc catcaaaatc ttctaatgtg aatggtccat tataaacagc tttatcactt
    10321 gcagatgcat aggcatcccc attttcttcc actacggatt gtttttgtgg gaaaaatgat
    10381 gggaaagcaa gcagatattg gaaatatggt gtttgtttcg tcaatttgat ttctaattca
    10441 tagtcaccaa ctgctttgat ccctagttct gatttatctt tctttccagc tgtaatgtct
    10501 tctgcatttt caactggcgc atacaggtaa gcatattcag aagctgtagc tgggtctact
    10561 gttcgttgcc agccataaac gtaatccgct gctgtaacag gatcaccatt tgaccatttt
    10621 gcgtcttctc gtaatttgat tttgtaagtt aatccgtctt cactgacttc tgccaactcg
    10681 ctagctcctg ccggctgtgg tttgctgtct tcatcaagac ggtaaattcc ttcataaacg
    10741 ttattcaatg ctgtaaaact gattgtatct gttgcaactg ataagtcagc tgtaggcatt
    10801 tcttgaggca cgactaagtt aaatacgcct cctccatctg ctgaaccgct ttttgctgaa
    10861 ctactgcttg tggctgaact gccgccataa catccagcaa gtacaaggcc gcataccgca
    10921 accaaaccaa atgtaaattt ctttttcatt ttacgtaccc ctttattgga attttcagaa
    10981 taattaatat tttctgaagt tgtttaagag tttaatgaat aattattaaa aaatcaacac
    11041 ttttttttgt ctttttcata aaataatgat tttttcgtga ggtttcaagg aatttttcag
    11101 aaaaaatagc tttgtacaag gttttccatg gtcttccaaa agccattaaa taattttcgt
    11161 tatattgtct attattgcca tacaaagata aaaaagaata aacaaaaaga aactgtgaca
    11221 aaagtcttgt cacagtccct tatctgaata aacggtgttc aaaagccagt ttctcggtat
    11281 taagccaaat t
//
LOCUS       DADQCX010000087        11184 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.088, whole genome shotgun sequence.
ACCESSION   DADQCX010000087 DADQCX010000000
VERSION     DADQCX010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.088"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            102..338
                     /gene="secG"
                     /locus_tag="J8R83_002210"
     CDS             102..338
                     /gene="secG"
                     /locus_tag="J8R83_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAZ9575327.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            450..1196
                     /locus_tag="J8R83_002211"
     CDS             450..1196
                     /locus_tag="J8R83_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9575328.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            1199..3556
                     /gene="rnr"
                     /locus_tag="J8R83_002212"
     CDS             1199..3556
                     /gene="rnr"
                     /locus_tag="J8R83_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAZ9575329.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            3578..4042
                     /gene="smpB"
                     /locus_tag="J8R83_002213"
     CDS             3578..4042
                     /gene="smpB"
                     /locus_tag="J8R83_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAZ9575330.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            4344..5063
                     /gene="atpB"
                     /locus_tag="J8R83_002214"
     CDS             4344..5063
                     /gene="atpB"
                     /locus_tag="J8R83_002214"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAZ9575331.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            5116..5331
                     /gene="atpE"
                     /locus_tag="J8R83_002215"
     CDS             5116..5331
                     /gene="atpE"
                     /locus_tag="J8R83_002215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAZ9575332.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            5422..5946
                     /gene="atpF"
                     /locus_tag="J8R83_002216"
     CDS             5422..5946
                     /gene="atpF"
                     /locus_tag="J8R83_002216"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAZ9575333.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            5933..6475
                     /locus_tag="J8R83_002217"
     CDS             5933..6475
                     /locus_tag="J8R83_002217"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAZ9575334.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            6498..8054
                     /locus_tag="J8R83_002218"
     CDS             6498..8054
                     /locus_tag="J8R83_002218"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAZ9575335.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            8068..8970
                     /locus_tag="J8R83_002219"
     CDS             8068..8970
                     /locus_tag="J8R83_002219"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAZ9575336.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRAVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            8993..10399
                     /gene="atpD"
                     /locus_tag="J8R83_002220"
     CDS             8993..10399
                     /gene="atpD"
                     /locus_tag="J8R83_002220"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAZ9575337.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            10413..10835
                     /locus_tag="J8R83_002221"
     CDS             10413..10835
                     /locus_tag="J8R83_002221"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAZ9575338.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         3710 a         1988 c         2471 g         3015 t
ORIGIN      
        1 ttttgaactt tcagctgtta ttccatttat atagagttgt cacggacttt tatctatgat
       61 aaagttaaag agacgatatc ttttgggaag gaggctgcga tatgtataat ttaattttgg
      121 gaatcgtgat cgttttatcg attgttatgg tcattgcgat tatgatgcag ccaagcaagc
      181 aaaatagtgc agcgagtgca tttaccggcg gtgcggatca actattcggc aaacaaaaag
      241 ctcgcggctt tgaagctgtc atgcagcgat caactgcagt tatgggagct atctggatga
      301 tcttattatt tgtcctagca tatttatctt cgaagtagtt gaataagcct ctcgcaaaac
      361 ggcgggcggc tttttttatt gcaaagagaa cgcttaagaa gaagttatga aagaaactat
      421 ggtaaaatga ggcgaaagag gtgagacgag tgagacaatt accaaaaccc ctttatgcaa
      481 aacatggaaa gcgagcggtt ttgctgcttc acgcttactc aggaagtcca aacgatgttc
      541 gaatgctcgc acgatttttg gaaaaagcag attatacagt ttatgcgccg ctttttaaag
      601 gacacggaac aatggagcca tatgatatct tgcaagaaaa agcagaaagc tggtgggcag
      661 acactaaaaa agccatccat tttttacagt ctgagcagtt ttctgatatt gccgtattag
      721 gattatcaat gggcggcatc tttgctgtac gagcactaga agaagaatca gtgattggcg
      781 gcggtttttt ctgttcgcct ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa
      841 aatacgtacg tcaagtgctg aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag
      901 cagttgctta ccgctcgtta gctgaacaac aattaatgga tatacaagat caggcagcaa
      961 tcgtagaaag taggttgtca gatatccaac agccgatatt tttagctcaa gctgggaaag
     1021 atgaaatgat cgaccctaat ggcgtatttg aaactgcacg caagttgagc cgtcagcgag
     1081 tgacacttca atggtatcct gaaagtggtc atgtgattac agttggtaca gcaagacgcg
     1141 aattagaaaa agacgtcttg gaatttttag aaaaattacc ttggaatgag gaataaatat
     1201 gacaaaagaa acgataaaag agaaaattct ctttttcatg gaaagcagtc gcaaacgcag
     1261 tttttctatg gaagaaatcg ctgaaggttt agggttccaa aaaagcgatg attttaaatt
     1321 actagtacaa acgattgctc aaatggaaag agaacagagt atagttttca ataaaaaagg
     1381 aaaagtgaaa cttcctttaa aaccaatctt gatcgaagga acatttcgag caaatgaacg
     1441 aggatttgga tttgtaacga ttgatcccga agaagatgac atctatatcc caaaagaagc
     1501 gactggtttt gcaatggatg gagacaccgt agcaatcgat atcatgaagc gagcaaatac
     1561 agatatggat cgcggagcag aggggaaagt agtcgagatt cgagaccggg cgactactca
     1621 gttagcaggg gaattcgttg cttattcaga agaagaaata caagaaacag atctttacgg
     1681 cgttgttatc ccgaaagata gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg
     1741 agttcgtcca gttgacggaa gtattgtgct gatcgaactg acccattacc ctgaaaaagg
     1801 gtatgcgact agtttagaag ggataatcaa gcaagtgatt ggtcataaga atgaccctgg
     1861 catggatatc ctctcaattg tcgtggctaa tggtatccct acgaaatttc ctgatgatgt
     1921 attgtctgaa gcagatgaag ttccagatca aatcagcgaa aaggatataa ctggacgtag
     1981 agatttaaga aatcagctca ttgttacgat tgatggagaa gatgcaaaag atctagatga
     2041 tgcagttacg gttaaaaaat tagataacgg taattatttt cttggagtac acattgcaga
     2101 tgtttcttac tatgtgacac aaggcagtca attggacaga gaagcatatg aaagagggac
     2161 aagtgtatat ttgactgatc gagtgattcc gatgatcccg caacgtttat cgaatggtat
     2221 ctgttcactg aatccccatg ttccaaggct gaccatgagt tgcgaaatgg agattgatcc
     2281 aaatggacaa gtagtctctc atgatatttt cccaagtgtg atccaaacaa cagaacggat
     2341 gacctacaca gctgtcaatc aaatcttaga agatcaagac gaagaaacga tgcaacgcta
     2401 tgctcagctc gtacctatgt tccaagaaat gggtgaattg catcgaatcc ttgaaacgat
     2461 gcgaatcaaa cgtggcgcga tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc
     2521 tgaaggacac ccaaatgaca tccagctaag aagcagagga attggtgaac gcttgatcga
     2581 atctttcatg cttgcggcca atgaaacggt agctgaacat tataataaat taaatctgcc
     2641 gtttatttac cgaatccatg aacagccaaa agaagaaaaa atgcagcgct tctttgattt
     2701 tgcttcagct ttgggcattc tggtccgagg aacgaaagga acgatcacac caaaagattt
     2761 acagcatgtg atcgaaggag tagaagacaa accagaagct gcagttatca atactatgtt
     2821 gctaagaagc atgcaacaag cacgctattc agaagacaat tttgggcatt atggcttagc
     2881 ggcagattac tacacacact ttacatctcc tattcgacgc tatcccgatc taatcgtcca
     2941 tcgtctgatc cgttcttaca gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc
     3001 ggaacttcct gaaattgcag atcatagttc taagatggaa cgtcgtgcag tagaaacaga
     3061 acgtgaagta gattccatga agaaagcaga attcatgatg gacaaagtgg gagaagaatt
     3121 cgatgggatc atcagctctg ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt
     3181 agaaggattg atccatatca atgaattgaa acaggactac ttccattttg ttgaaaatca
     3241 tttagctctt gtaggtgaaa gaactggtct gacttttaaa atcggacaaa aagtgcgcgt
     3301 aaaagtagtc aaagctgatc cagatgaacg agcagtggat tttgaactcg tttccgcaga
     3361 agaggtcact gcgttggaac gtccaaaagc acgcaatgga aaatctggaa aacgagaagg
     3421 aaaacaagca ggcaaacgct cagaaaaaaa tggcaagaag aacaaacgat atagtgatag
     3481 taagcaaacg ttcggtaaga aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa
     3541 gaaaaagaaa aaataaaatg agttggagga aacagctatg ccaaaaggcg agggaaaact
     3601 aattgcacaa aacaagaaag ctcgccatga ttattcgatc atcgacacga tggaagcagg
     3661 gatggtcttg caaggaacgg agatcaagtc gatacgaaac agccggatca atctgaaaga
     3721 tggatttatt cgcgtccgca acggggaagc tttcttgcat aatgttcata tcagtcctta
     3781 tgaacaagga aatattttta atcatgatcc gttgcgcacg agaaagttat tattacacaa
     3841 gaaacaaatc gttcgtcttg aaaacgaatt gaaaaacact ggaatcactg ttgttccttt
     3901 aaaagtctat attcgtaacg gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa
     3961 atcgtatgat aaacgggaag atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac
     4021 attaaaaaat ttctctagat aatttcatta tcctttttcg catattcggt gcttttgctt
     4081 ttacttaatg ataaaatttg ttagcattta atctgataaa acatgattat cacaggtttt
     4141 ttcttagatc aggagcaccg tgcatgggga aaaattcgct tcgtttttga ctgaaataaa
     4201 aaagtgtcta attttcatga aaatgttttg aattttctgt ttcatggtgg tatgataccg
     4261 tgtggttaga aaccgattgg aaaaaaccag atacgcacat gaattgattt tatgtgaatt
     4321 tcggggaaaa gaggtgaaat ggattggatg aacgctcgct aacgtttcac attggaccaa
     4381 tttggtttga tggtacagtt tgtataatgg tgttactgac ctgtttgatt gttttcttct
     4441 tagcttactt ttttacaaga aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag
     4501 aatgggtcat tgattttagt cgaggaatcg taacagataa tctgcctaga aaagaattga
     4561 gcaatttcca tttgttggca tttacattgt ttttatttgt ttttgttgca aacaacatag
     4621 gtttagtaac aaaaatcgtc ttacctaacg aaacaacact ttggaaaagc ccgacagcag
     4681 acccgtttgt tactttaact ttggcattta taatgatctt acttactcac ttattcgggg
     4741 tgaaaaagtt aggcttcaaa ggatatttcg taaattcgtt cttgaaaccc tatagtttta
     4801 tgtttccgat gaaactgatt gaagaattta caaatttatt aacacttgct ttacgtcttt
     4861 atgggaatat ttatgcgggg gaagttttgc taaccttgat tgcaaaaatg atgacaagct
     4921 taggctggtt ctcattacca ttagcaattc cattagagat ggtctggatc gcgttctcct
     4981 tgtttattgg gagcatccaa gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc
     5041 ataagattga agtagaagaa taatactcgg ttaaaaaaca aactactatt tatctatttt
     5101 aggaggaaaa caattatgaa ttatatcgca gcagcaatcg caatcatggg agcagcaatc
     5161 ggagccggtt atggtaacgg tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa
     5221 cctgaaatgt ctggtcaatt ccgtacaaca atgtttatcg gggtagctct agttgaagct
     5281 gttcctatct taggggtagt tatcgccttg attctagttt ttgccgttta attgaatcag
     5341 tattaaggca gaaacaacat cgtttgttac tgctttttta catggaaact agaaatactc
     5401 caaagaaagg aaggctcgcc tatgctgaat caattggcaa ttgcagaagt tggcaatgcg
     5461 atgttaggta atatcatcgt tgtcagcggc tcatttttga tactactggc tctcttgaag
     5521 cactttgctt ggggaccaat cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat
     5581 gatttagatt ctgcagaaca atctcgcatc aactcagcga aaatggaaca agaacgcgaa
     5641 caacaattgt tagcctctcg ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt
     5701 ggagaattaa gccgccaaaa tattttgaag gatgctcaag aagaagcagc tcgtctaaaa
     5761 agcaaagccc aagctgatat cactgtagaa cgtgattcag cgctgaactc tgtaaaagac
     5821 gacgttgcag aactctctct tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca
     5881 gaaatgcatg aatcattaat caatcaatac attgaaggtc taggttcttc aaatgaaact
     5941 agataaatat acagtaggaa gacgttacgg gaaagcttta tttgaactgg cgatcgattc
     6001 aaatcaagca gaagaaatct atcaagatct cgtaagttta cgtcaaatct atgaacaagt
     6061 acctggatta gggaatatgt taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat
     6121 catggacaag cttgtcagcg gttatgatgg gatcgttaaa aactttttag aagttgttta
     6181 tgagtataac cgaatggatg accttttgtt catgatcgaa gaatatgaac gtcgatatga
     6241 tgaacatcaa gggttactat tgggaagtgt cacaacagca gtcccacttt cagacgaaca
     6301 acgaatacaa ttagaaaaga atgttgcaaa aacaatggac tatcaatcag ttgaattaaa
     6361 acaaatcgtt gattcttcta ttattggtgg cgcgattgtt gaagccaacc atcgagtaat
     6421 cgacggaagc attcgcacgc aattagaaaa aatgcgtaat caattaaaca gatagtacaa
     6481 agaggtaggt gaatcgaatg gccatcaaag cagaagaaat tagtgccttg attaaagaac
     6541 aaattgaaaa ttatcaaaac gtgctttcag tcgaagaaat cggtaccgta acttatgtag
     6601 gtgacgggat cgctcgtgca catggtttag aaaacgcgat gagtggtgag ttgcttgaat
     6661 tttcaaacgg ctcatacgga atggcgcaaa acttagagtc aaatgatgta ggtatcatta
     6721 tccttggcga tttcgagtcc attcgtgaag gagataaagt aaaacgaaca ggtaagatca
     6781 tggaagttcc agttggagag gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa
     6841 tcgacggact aggtgaaatc gttactgaca aagctcgtcc agtagaagcg atggcaccag
     6901 gtgttatgca acgtaaatct gttaacgaac caatgcaaac agggctaaaa gcgatcgacg
     6961 cccttgtgcc aatcggacgc ggacaacgtg aattagtcat cggtgaccgt aaaacaggga
     7021 aaacttctat tgcgatcgat acgatcatca accaaaaagg tcaagatatg atctgtatct
     7081 atgtagcaat cggacaaaaa gattctacag ttcgtacaca agttgaaaca ttgaaaaaat
     7141 atggcgcaat ggattacaca atcgttgtga atgccggtgc gtctcaacca gcaccattgc
     7201 tttatatcgc accatatgct ggtactgcaa tgggtgaaga attcatgtac aacggtaaac
     7261 atgtattgat catttttgat gatctttcaa aacaagctgt tgcttatcgt gaactttcct
     7321 tgctacttcg ccgtccacca ggtcgtgaag cttatcctgg ggatgttttc tacttgcact
     7381 cacgtttatt agaacgtgca gcaaaattaa gtgatgattt aggtggcggt tcaatgactg
     7441 ccttaccatt tgttgaaaca caagctggag atatctctgc ttatatccca acaaacgtta
     7501 tttcgatcac tgatggacaa atcttcttag aaagcgactt gttctacgca ggtactcgtc
     7561 cagcggttga tgccggacta tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa
     7621 tgaaaaaagt tgctgggact ttacgcctag acttagcaag ttaccgtgaa ttagaagcat
     7681 ttacacaatt cggttctgac ttggatgcag caacacaagc aaaactaaat cgtggacgcc
     7741 gtacagtaga aatcttgaaa caaaaattgc atgcaccgct agctgttgaa aaacaagtag
     7801 tgattttgta tgctttgaca catggattct tagatagtat ccctgtagac agtattttag
     7861 acttcgaaca tgaattattc gaatatctgg ataccaatca ttcagatatc tttgaaacaa
     7921 tccgtacaac aaaagatctt ccagaagaag aagcgttgaa cagtgcgatt caggaatata
     7981 aagacatgtt cttagctaca aaaggaagta attcctctac agaagataaa ttgaaatcca
     8041 ttcaaaatgc atagtgaggt gagatgaatg ggtgcttcat taaatgaaat caagacacgt
     8101 atcgcttcaa cgaaaaaaac gagccaaatc acgcgggcaa tgcagatggt gtctgcttct
     8161 aagttgacaa aatctgaagc ttcttcacag aagtttcagg tttatgcaac aaaagtaaga
     8221 gaaatcgtta cgcatttgac tgctactcag ttaaatgata ttgcctcaga aaatcctaga
     8281 ggggatatca attacaacag catgctgctc agccgtgctg tgaagaaaac tggttatatc
     8341 gtcatcactg cagatggcgg tttagtcggt ggatataaca gctcgatatt gaaacaaacg
     8401 atgtctattt tagaagaaga ccaccaatca cccgatgatt acgtgatgat cgcaattggc
     8461 ggaactggtg cagacttctt taaagcacgc ggtatcaatc tagcatatga gctgcgcaat
     8521 ctatctgatc agccaagctt tgatgaagtc cgcaaaatcg taaatatggc aacaactatg
     8581 ttccaaaacg aagtattcga tgaattatac gtatgttata accatcatat caattcgcta
     8641 actagtcagt ttcgtgtaga aaaaatgctg ccaatctcag acttagatcc agaagaagca
     8701 acgactttcg aacaagaata tatttttgaa ccttcaaaag aagaaatctt gtctcagtta
     8761 ttgcctcagt atgctgaaag tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa
     8821 catgctgctg gtatgacagc aatgaaaaca gcaactgata atgctgctaa tatcattgat
     8881 gagctgacgg tttcttataa ccgtgcaaga caaggggcta ttacccaaga aattaccgaa
     8941 attgttgccg gagcttcggc actagaatag tattgagatt ggaggaaaaa agatgagttc
     9001 aggcaagatt gttcaagtaa tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc
     9061 cttaccagat atcaacaacg cattagttgt ttataaaaat gacgaaaata aatcaaaagt
     9121 tgttcttgaa gcagcgttag aattagggga cggagtgatc cggaccattg cgatggaatc
     9181 aacagatggt ttacaaagag gaatggaagt cattgataca ggcaaagcaa tctctgttcc
     9241 tgtaggtaaa gaaacattag gtcgcgtatt caacgtacta ggagatacga tcgatttaga
     9301 aacacctttc ccagaagatg cggaaagaag cgaaattcat aaaaaagcac cagcctttga
     9361 cgaattaagt acaagtacag aaattttgga aacagggatc aaagttatcg atttgcttgc
     9421 cccatattta aaaggtggga aagtcggact attcggtggt gccggtgttg gtaaaaccgt
     9481 actgatccaa gaactgatcc ataatatcgc ccaagaacat ggtggtattt ctgtatttac
     9541 cggtgtaggt gaacgtactc gtgaaggtaa tgacttgtat tatgaaatga aagattcagg
     9601 agttatcgaa aaaacagcca tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat
     9661 gcgtgttgct ttgactggtt tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga
     9721 tgtactgttg tttatcgaca acattttccg tttcactcaa gctggatctg aagtatcagc
     9781 cttgttagga cggatgcctt ctgcggttgg ttatcaacca acattggcaa cagaaatggg
     9841 tcaattacaa gaacgtatca catctacgaa aaaaggttcg atcacatcga tccaagcaat
     9901 ctatgtgcca gccgatgact acactgaccc ggcgccggca acagcattcg cccatttgga
     9961 tgcgacaacc aacttggaac gtaaattaac agaacaaggg atttatccag cggtagatcc
    10021 attggcttct tcttcaagtg ctttagcacc tgaaatcgtg ggggaagaac attataaagt
    10081 agcaacagaa gtccaacacg tattgcaacg atatcgtgaa ttacaagata tcattgctat
    10141 cttaggtatg gatgaattat ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt
    10201 ccaattcttc ttgtcacaaa actttaacgt ggctgaacaa tttactggtc ttccaggttc
    10261 atatgtccct gtagaagaaa cagtgaaagg attccgcgaa atcttggaag gcaaatacga
    10321 tgatcttcct gaagaagctt tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc
    10381 gaaaacacta ggctactaga aaggggtgcc ccatggatca atatttaaca gtaaatgtgg
    10441 taactcctgc cggtttggtc tatgatcacc atgcagctat cgtcgttgca cgtacgacag
    10501 ctggtgagct tgggattttg cctaaacatg caccaatcat cgttccattg acgattgatg
    10561 aagttcgtgt aaaacgaaca gattcagata cccacgtcga ttggatcgct gttaatggcg
    10621 gaatcatgga agttcgtgat aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac
    10681 gtgatatcga tgtatctcgt gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag
    10741 aagcaaaagc aaaacaagat acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag
    10801 caatcaatcg tatcaaagta tctaagcact cataaaatga gatgcggatg tttatccgtg
    10861 tttaagaaca gtaaaaagag gttatgacag aagtggtcag cttcaagaca taagaaggaa
    10921 tttacgaaaa ttgcttctca aatttttgtg aaatctcagc ttatttttcg aagaagctac
    10981 ttctggaaca ccgtatatca gaggttgtaa aatcagcgtt ttgtcctgag tattagagaa
    11041 acaaatggaa aatagttcct catattttgc cgttttttga gctaataccg agggtcagat
    11101 gattgaacac cgtttatttg ggctctttgt caaatgatgt tggtaaagag aaatcttaga
    11161 ataatttgga cagaacagaa agaa
//
LOCUS       DADQCX010000088        10696 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.089, whole genome shotgun sequence.
ACCESSION   DADQCX010000088 DADQCX010000000
VERSION     DADQCX010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.089"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..736)
                     /locus_tag="J8R83_002222"
     CDS             complement(<1..736)
                     /locus_tag="J8R83_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9575339.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFA"
     gene            1227..1433
                     /locus_tag="J8R83_002223"
     CDS             1227..1433
                     /locus_tag="J8R83_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAZ9575340.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(1635..2636)
                     /locus_tag="J8R83_002224"
     CDS             complement(1635..2636)
                     /locus_tag="J8R83_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575341.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(2641..4554)
                     /locus_tag="J8R83_002225"
     CDS             complement(2641..4554)
                     /locus_tag="J8R83_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAZ9575342.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(4722..5228)
                     /locus_tag="J8R83_002226"
     CDS             complement(4722..5228)
                     /locus_tag="J8R83_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9575343.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            5388..5828
                     /locus_tag="J8R83_002227"
     CDS             5388..5828
                     /locus_tag="J8R83_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAZ9575344.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(5854..7011)
                     /locus_tag="J8R83_002228"
     CDS             complement(5854..7011)
                     /locus_tag="J8R83_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575345.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(7014..7370)
                     /locus_tag="J8R83_002229"
     CDS             complement(7014..7370)
                     /locus_tag="J8R83_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575346.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(7668..8642)
                     /gene="sgrA"
                     /locus_tag="J8R83_002230"
     CDS             complement(7668..8642)
                     /gene="sgrA"
                     /locus_tag="J8R83_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAZ9575347.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(8838..9677)
                     /locus_tag="J8R83_002231"
     CDS             complement(8838..9677)
                     /locus_tag="J8R83_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAZ9575348.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            9862..>10696
                     /locus_tag="J8R83_002232"
     CDS             9862..>10696
                     /locus_tag="J8R83_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAZ9575349.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNNDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VM"
BASE COUNT         3197 a         2126 c         1633 g         3740 t
ORIGIN      
        1 cagcgaaata aatggcaata tcattggcat tactgatctg tttccaattt gaaaattcct
       61 ttccacaatc aaaagtgatg gatttgaata gatttttcgg tacagattca aaccaatgat
      121 ttaatttgtt ttcaatatca atcgcttgtc taccacacgg tttcaatgtg atgataactt
      181 ttgataatcg ctcaactaag gtaattacag cacttttatg tttcaaacct acgatagtgt
      241 caccttcaag gtgaccaaac tcatttgaga attggctata atctttttca cgttcatgaa
      301 tagagcgacg gaaagcttgt tttccacgtc tttcttgatg tccatttggt ttacgcttgc
      361 ctttcatcgg taagtcagaa ggattaaata gccccttttt gaacatacga taaatggtac
      421 gagcagaaca acgaatagga aacgctgcac gaccaacaat cacatcgggt gtccatcctt
      481 gaacaacctt tctttgaata tattctgatt gttcctcagg taaaacaagc gggcgtctac
      541 cacagtttga tttgtttttc ttatactgtt gatagtactc taaggctgat tttccttgct
      601 tgaagaacag gtatacttta tggatcgttt gtcttgaacg attcaagcaa tgcgcagttt
      661 tcgcaacaga ttgatttatt ttgaaataag actctatcat tacaagttca tccgttgtaa
      721 gatgggtata ggtcatttgt actcactcct tataattctt tggacggaac tattttgagt
      781 gtagcacaaa tgactttttt agttgtctag cttaatttta caatcggcgt tttctaaaaa
      841 attaaaaaaa attttggtga attaagtatt tccttgataa cactggcttt tggcctcatt
      901 ttaggttatc atttgtaatt ttatttcaca gttgatatga ttgttatgta aaataaaaaa
      961 gtttaggata catcgaattt ttggggaaat tcttttgggg gtatcctaaa tcttttctat
     1021 tatattccca tattttctat tattggtcta gacgtatgat ggtaaacttt gtacctatct
     1081 gattgctgaa tcattaattg cttatcatta gccatctttg tttcaagttc gctagatgat
     1141 cattttattc acatcctaac aaacttgtca catttataga ttcttaatct atttatcata
     1201 caattataaa aaaggaggtg ctgcttatga aagctatcca tatttctttg ctttttttcg
     1261 ctagtgcatt gattttattt gctattcatc tttgttccca gccttatatc aataacaacg
     1321 gaatattagt ggaaccagca ttcttttgct taccactcgg ctttttgtcc cttcttgcct
     1381 ccgcaggctt cggatttgtt gcttttttta aacgatcaaa acaacaaatc tgacttataa
     1441 aatttacgta aaagagatcg tgacaataat cgtgtgatat tcccaaattt cgaataaaag
     1501 gtgccccttg ccatctctaa ctcctcagtc acaagttaca atattcataa accatgaaaa
     1561 gcttgtttat tgaaattgct ccttgtgact tggagctaag tgacagatta caacctcttt
     1621 tgcatcataa gactttactc cttgaaaaac attactaact tttgatatgt ttcttgcgct
     1681 tgtttattgc tgaaatcaaa ctgatattca tggttcaaaa cagcattttt ctccgcataa
     1741 tctacttttg tgactttcac ccccgctttc tcaaatacag aagttacttc ttccatttgt
     1801 ttcgtaaacg tatttgtatt tccatccgtt aagaatgtgt tttgcgtcca acgatccgca
     1861 tgtctgacca aggctaaact tttgaccttc tctgattgtt caaagtcctt attatcaaag
     1921 taagcccatc cacatttttc ataaagaaag ctagagattt tatcacttac ttgagtaagt
     1981 gcagaaggat ccaacagacc agacaaagaa ataaacttcg taatctgctt gttctccaaa
     2041 gtcggatcaa gatgatcagc ttttttaatt tcttcatttt gaagtgctaa caaatattct
     2101 ccactaattt gtgcacctgc cgaatttcca ccaatcgaaa tattcgacca atctgcttga
     2161 tcttttatct cttttttagc tgcttgaatg gcttcgttca attggataac tggtgtagga
     2221 tgttttgctt ccggtgatcg ttcataatct atatttacga tgatttgctg cgtgtctgaa
     2281 catagatatt ccaaataatc acgacaatca tttttatccc ctcctacata tgcgcctcca
     2341 tgcatccaga aaagaatcgg taattttttc ttttccactt tcggtgtgta gatatccata
     2401 ttattatttt tgtactttga aggataggat atttcttttt ttatatcgat ttgttcgatt
     2461 ttttgctgga aatcatctgg tcgggcatat acttgttctt tttcacttgt gtcaaattgt
     2521 tttctaacaa gcaagctaat cggctttggt gtgatttgat taatcaaaaa tacagtgact
     2581 aaaataacta cgatgataac tggtactgca atcactattc gcttgaacca tttcattcat
     2641 ttaccctctc tttcttcgcc aaatccatgt gataatcgtg ctaacagata aaaatccacc
     2701 tgaataaatg agaagcgaat gtttcttttc tccagttttc ggcaacattc ttttttttgc
     2761 atctgtcttt ttttgtactt tcactgtcat ctgaatcggt tgcgtatcat cacttgattg
     2821 atcctctcga ggttcattct ttcccttatt gtctgcattc tctgtcggat cttgcttttt
     2881 tggtggagct actgggattt ttttgtaata gaaaataata gttggtatcg tctcattaaa
     2941 aatcccttca gtcggtcctt caacatttgc taattcgtat ccttcgaatg tcttttgctc
     3001 tgtcatataa ttttctccat aagctccgta aagctggatt tcgtcctggt ctttgagtag
     3061 acttttattg ttttcatcca catactttac gtttatctga tcatggaaca ctactttcaa
     3121 aaagtccgtt acatgtttcg tgtaggcagc atggtcaact tcctgtgcct ttccatgccc
     3181 tgctccttct actaataaaa gatctttata ccctcctgat aactcatata atttttgcgc
     3241 gttagacaca ggtactacat catctgctgt tccatggata atcaatttag gcaatgaatc
     3301 tgacattcca atcgtaggta gagcagcttt tgtatccaaa tgcatctcct gatcaaaata
     3361 gtattgtttc aaaaggccca taaataaatc ttcatgctct tgatccccaa tgatgtctaa
     3421 ctgatttttt atggcatccg gtagtgcggg ggctactgtc tggctgtacg taaaacgtag
     3481 ttgttcatca attgatgcaa atccgcaatt ttcaataatt cctttgacat tgacaggaat
     3541 atctttcgct aatacagaca tcatcgtagc tgctcccatc gaaccaccat aaagtaaaat
     3601 cttttgagat ggccgctctc gaacttcttg atttatccag taaaggacgt catctgactc
     3661 atattgtcca taggtcacat aatcgcctcc gctattacca gtcgctctgg aatcaacaaa
     3721 taataaatta tacccggcct tataaaaatc attgtattct tctgtaacga tcccgttatt
     3781 ccaattccct cgaaatccgc catggatcat gactgtttta tctgaacctt gatcgacata
     3841 atatgcatat acatccatca ttttgccatc ttgtttgttt agtacagttt gatgaagttg
     3901 ttttgtattt ggatagaagc ctgtgttttc tgtaggcgtt gtcccatcat ctgtacctcc
     3961 aagcatcgac atcaacacac tgttttttgc aaaagcgata tcgtacaata gataagtagc
     4021 aatcagatgt ttgataatct ctttatctac accataatca ttaacagcaa gctcagtgac
     4081 taataactct attaattttg acttgatgtc ttctgttggt ccattaagta tttctgtcat
     4141 ctgtttaccg aagtaattca aatattcttt accattgaaa ttttcacctt taccgatatc
     4201 atcattttct gtcccattct ctttgtcact tactttagca gaagaggatt cgtcgtttga
     4261 catttttgta gctgttgctt cttctgtttg ttggttatct gtggtagcgg tcgtttcttg
     4321 atctgtgcta gtaacagatg tctcaaccgt tgtttcagta tttgtttctg tttgtgaagt
     4381 actcgatttc gtttcatttc cagcatcagt agtttctgtg gtttctacct cccgagattc
     4441 cgattcggaa gaaatgctct ctccatatac tgtccattgc gggacgcttg tacttacagc
     4501 aaataagatg accaacgctc cctttaatac ttgttttgtt ctcaagctat tcactccttt
     4561 ttatgtttct aggagaatta tatgtaaacg caaacatttt ttatacaaaa aataaatggt
     4621 ttatcccata aaaatagaac aggattattt tctcatttta cgtaataaag cagaatggat
     4681 aaaccagtat ccattctgct ttttttaaac gaagaaacaa cttattgctc caaaaatgtc
     4741 agaaatcgtt tatcccaaat tttctcgtaa aaagcgattg tttcctttgc tttcataaaa
     4801 ggattatcat aagttgtcgt tgctcctcta cacatcataa gctggtatcc taatccatga
     4861 gcaaacttca cagtcgtatc tatacaatac tctgcttgtg ccccacataa ttcgatcgaa
     4921 tgacagtcca attcagttaa taaaacactc aaattagtct tataaaatga attcgcatgg
     4981 gtttttctca caaaataact gtgctcagga atagataatt ccgacaatag ctcccatggt
     5041 tttgtttgtg gcactaattg agcatcttcg tgttgaacga aaataactgg tttcccaatc
     5101 gtttcgtatg ttttgattct tttattcact aatgctgtca ctgtttctaa ttcgtgtatc
     5161 ggcgaagaat caaaacatac ccctttttgt aaatcgatca ctactattgc gtcggctgtg
     5221 tttgacatac ttgtgccttc tttctttttt cttgatttaa tagtatttct tatctagcta
     5281 gttccattat acgtgacaac attttcttat tttacacctc taaatggcac ttttcgacta
     5341 tttcttcatg ttattatttc ataaatactt agctattgga ggaatgtatg atgattaaat
     5401 tgtatacagg ttctggctgc tcgtcttcaa gacgcgcaaa acgttggctt atcgtccatg
     5461 atataccgtt tatcgaacag aacttaattc gtcaaccact aaccaaaaat gaatttatcc
     5521 acttactaaa attgacaaac aacggcgtga ccgaaatgct ctctactcat tctattagtt
     5581 ataaaaatct tgttcacaga atagatgaac tcagtttgag tgaactatat attgagattc
     5641 gtacatcccc ttctttattg aaaaaaccga ttatctacga ccaatctgca aaacttttga
     5701 ctggatttag cgaagataaa atcaggatgt tcctttctaa aactaaaaga aagcaagagc
     5761 tcaacgaact cttgctttct ggtcatcttg tcgattttaa agaaaataat ctttttgcaa
     5821 tgtcttaatt ttggcataaa caatctgctt ttcttaatta acgaaatcca atttttccaa
     5881 tatggatcta tttttctcat tcctgatttt tatgatttca gctttcagac gcgcccaatc
     5941 attttttgta ggttgtccat tccagtaaaa tatctgtgta ttcgtttgat catatgcctt
     6001 tttgtcgata ggataatcgc taatgacaat atcaggtaac tgatcagcgg atgcactata
     6061 ttttattggg cgttcagtca tagataatat ccttttcttt gcccataatt cctgtgtttt
     6121 accatacttt gattgaatat agaatatgac aggttgttcg tgttttataa aaatatccct
     6181 gactaacata cagtattgaa aaatcaaccg tctgttcttt tcataataag tattaagctc
     6241 tggaattctg cgagctaccc cactaaaaaa ctgttgcatg attggataca tcactggaaa
     6301 tatatgctga aaatctctgt cttctgctga ttttccaaaa gcatccacct tcttttttgt
     6361 cccaaaaacc cttgaataca aatggatcat tgccaaattg acatatagat aatttttttc
     6421 tgaagttgta aaacaaatct tgaagttttt ttcaaaattt tctacaatag acgattcaat
     6481 ccagccccaa ctttcttgta ctttatctgg agtatccaac aaatcttctt ccaaataggt
     6541 gttcattaca ccaaacataa aataaaggta agcttgctct gttggagtga tgtgattcat
     6601 cgaccagaag tttgcttcaa aaaaaggctc tagtatgtaa tgcgtaaact cttcttttgt
     6661 tatcaatgga tgcacaaatt tgttcatctc ttctgggaca tacgtaatcg agtggccttg
     6721 tttcattcgt tgcaacgaaa ttcttagtag gctgatccat ttctttctat ctatactacg
     6781 cgtatatggc gcatgtttcg caaatttttc taatagttga cgtttatttt ttatacttga
     6841 taatatatca gaatgatttt cgtcgaatga ctgccaatac atcaagtgaa aaaagtatcg
     6901 gatacggtat tcttctcctt ctatcggatt accttttttc aagctgcaag ataaatgata
     6961 gtttttcaaa atagtattaa gttctcttaa ttttctttga atcgtacgca aacttatata
     7021 attttttgac taagattttc taaggattga taagtacctt tgtaaagtga atccagtaaa
     7081 atataaccaa tcgttccctc taaaagtata gaataaactt tactcagtaa aaactgagaa
     7141 gaaaactcga cttttatcat cttgttttct gaaagaaaag ataatttata ttctggatac
     7201 ctttcgcaaa acgattctgc ttgttgaatc accgaattca tcttagccag ggtgtagttt
     7261 agatctaaag cgatatcctt caccacatat aatttctcgt ctctttcata acaatagttc
     7321 aaaaattgat atacttgcct ttcattgata tcaataaatt cttcaaacaa agtacatact
     7381 cctttttatc tattatttag acttattccg acagctacat gaataacgta caaatagatt
     7441 cgttactgat ttttcagaga tactaccatg cgcagtgtgc attgtcaatt attcttgctc
     7501 ttattttcca tttgtgttcc tgttatttcc tgtttctcaa atatgttagt aaacaaaaat
     7561 agatctggca aagctacaac ttcgccaggc aatacagcac tctcgaatga aatattcact
     7621 caaaaatcta tcgttttatt caattttaga tctgttgctt ttattcttta tttcactcga
     7681 tggaagagag aacgaaaata gcttgctcct acaatcaaaa tgagtaacac acccatccat
     7741 gtaattagct tgttcaaggt tctactacca gtttctggta aatcgctttt tctattatct
     7801 gtttctttcg ctttttcttg atgatcaatt ccacgagaaa caaaatcagg ctgttttagc
     7861 acacttttta ggttgctccc tgcatttctc ttttgttcct tagttggtat gataggtacc
     7921 aaatcaagtt cattatttac ttttcctgtg ctgctttcgc tgctcgtgct tcctgtgcta
     7981 ctctcactac tcatgcttcc tgtgctactt tcactactcg tactctccgt actgctttcg
     8041 ctgctcgtgc ttcctgtgct actttcacta ctcgtactct ccgtactgct ttcgctgctc
     8101 gtgttttctg tgctactttc actgctcgta ctctctgtac tgctttcacc gctcgtgttt
     8161 tctgtactgc tttcactact tgtgctatcc gtactgcttg gcggtccaac aactgtccaa
     8221 ctgcttggtt tcaaattctc cgtgatcgtc atctgtccat cataaaaaac aatcaaatca
     8281 actttatctt tactcttgat ctcatcaatc gatagttctg cagaaatcat tattgtatac
     8341 tcaataccag cggtccattg tacgtctttt aaataaactt ccccaataac tttttctgaa
     8401 cttccattac catcccaacc atatgttaga acagcatgta catcactagc attcacgctt
     8461 ttgtttggtt tgactggaat agtaatgact tgttgtgtca tgtcataaac aatccgatca
     8521 gttttcacag taaatgaaag attctcattt gcccgttcat ttgcagaagt actgattcca
     8581 atcattgctg caattatact cagcccaaga ataacaaata atacggtcgc tgttttcttc
     8641 atttctatca ctctccatat aattaccttc tatttgataa aggaattata taaaatgaaa
     8701 atgatgagaa cacgacagtc agttgtgaaa atctaacaaa agatgtcgtg tattcgcttg
     8761 aatttgttta ctttttcgtt taatcaatga cagacttaaa aaagcaagac cgatatcagc
     8821 cttgctttct tcatctttta ttgataaaca gcagtgtatt tcttcatccg ctttgtttta
     8881 tatgcataga gtaacaaacc aacaatcaag actaacaaga ataatgtagt tgatatagat
     8941 gcttcagccc caaagtttcc cccagtaatt attgtatttt gcgattggat cagagtggag
     9001 aaaaaacctt gttcttgcgt tccgctgact ggtataccca aaatagctcc ttgtgtccaa
     9061 ttccaagtaa tatgagcacc aatagccgta aataaacttc ctgtactgta gataagtgcg
     9121 ctgaaaaagc aacctgctaa aaagatattg aaaactgcca gaaatgtcat gttaggattc
     9181 aatccgtgca aaagagcaaa taatgcagca gatccaatca ttgctattaa cggaccaaat
     9241 ctaagcatct gatgctgaaa aaagccacgg aataaaagct cttctgatgc ccccactgca
     9301 ataaataaaa taaaactcgt tatcagcggc acaatgtttg cgtttcctga atctaaccga
     9361 tacgcccccg tcaaatataa tggactagta ataagcagaa acactccaat tccaacaacg
     9421 agacctcccg ctaaataccc ccagtctttt cctcgaacag aaacaccata atcttctatt
     9481 ctttttcctt cgaccttact agcaagaaat aaagctagta aaaaaacagc taaatgtccg
     9541 accgtaccgg caattgctcc aatccattca ctatttccaa taaacatatc cgcaagtgca
     9601 ttattgacaa gaattcctaa aacaaaacca actaagacta ttaaaacaga tccaatcaac
     9661 cgaataatcc tgatcatctt tcatccctcc tttatattaa gtttaacaac ccttttcttt
     9721 cttgtctcgt gaaaactatg taaatgttct ccatcataga gagaatagat ttttacgaac
     9781 taagaatatc tacagcaacc ttacgaaaat gaaagactgt ctccctaatt cttctgttag
     9841 actgttttta ataaggaaag gatgggaaat tttttgaaaa aacaactact aattatgtgc
     9901 ctttcagcat gtgcaatttt actattctca ggttgtagca agtccaatga aacgattgca
     9961 acgtttaaag gtggaacact tacagttcag gatttttatg ataacccaaa agttaaatca
    10021 aataatcaaa cactattaaa aaaaatgatt gtcttcaaag catttgatga tgtatacgga
    10081 aaagagattt cttcaaagga agtaacaaaa gaatataatg aacaaatcaa aaaactcggt
    10141 ccaaactaca aggaacaatt aaaagcagtt ggccaaacag aagagacata taagaaactc
    10201 tttaaacaga tgctggcttt ccaatacggt ttgaaagcca atgtaaaatt aacagataaa
    10261 gatctagaca ctgcttggaa agaattctat ccagaagtta gtacacagat cattctattt
    10321 tcgactaaag aagaagcaga taaagcaaaa aaagaagcaa atgaaggaga aaatttctcc
    10381 aagcttgttc aagcttatgg aaaaaataaa acattaaagg aaactgatgg aaaaatgaat
    10441 tttgattcaa ccaatccaga gattcctact gaagtaaaaa aagcagcatt taaactaaaa
    10501 aacggggaag tttctgatat cattcctgta acagatccaa cgacttatca gcaaagctat
    10561 tatctagtaa aaatggtaaa aaaacaggat aaaggttcta ataatgacaa atacaaatct
    10621 gagctagaaa aaattgctac cgaagcaaaa actcttgata cggaattcat ggataaaaca
    10681 atccgtaaag tgatga
//
LOCUS       DADQCX010000089        10605 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.090, whole genome shotgun sequence.
ACCESSION   DADQCX010000089 DADQCX010000000
VERSION     DADQCX010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.090"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            28..651
                     /locus_tag="J8R83_002233"
     CDS             28..651
                     /locus_tag="J8R83_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575350.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1101..2150
                     /locus_tag="J8R83_002234"
     CDS             1101..2150
                     /locus_tag="J8R83_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9575351.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2147..3028
                     /locus_tag="J8R83_002235"
     CDS             2147..3028
                     /locus_tag="J8R83_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575352.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3031..3801
                     /locus_tag="J8R83_002236"
     CDS             3031..3801
                     /locus_tag="J8R83_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9575353.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4080..4934
                     /gene="aroE"
                     /locus_tag="J8R83_002237"
     CDS             4080..4934
                     /gene="aroE"
                     /locus_tag="J8R83_002237"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAZ9575354.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5112..6275
                     /locus_tag="J8R83_002238"
     CDS             5112..6275
                     /locus_tag="J8R83_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAZ9575355.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6392..6802
                     /locus_tag="J8R83_002239"
     CDS             6392..6802
                     /locus_tag="J8R83_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAZ9575356.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6976..9204
                     /gene="topB"
                     /locus_tag="J8R83_002240"
     CDS             6976..9204
                     /gene="topB"
                     /locus_tag="J8R83_002240"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAZ9575357.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVILYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9342..9659
                     /locus_tag="J8R83_002241"
     CDS             9342..9659
                     /locus_tag="J8R83_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575358.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9819..10055
                     /locus_tag="J8R83_002242"
     CDS             9819..10055
                     /locus_tag="J8R83_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9575359.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10052..10450
                     /locus_tag="J8R83_002243"
     CDS             10052..10450
                     /locus_tag="J8R83_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAZ9575360.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3705 a         1771 c         2239 g         2890 t
ORIGIN      
        1 aaaataggag aaaaagtaga aaagaaggtg tttgttattt gggaagtagt taaatcgaga
       61 gtacaagaaa tgaatgaaca tttctcagtg tcattcgcag aaaatccaag taagtatttt
      121 cgacgtcttg tttttctgct catcttatca ttgctgttaa cagttgcaat gtttttattg
      181 ccggaaaaaa tccgagaaga gcaagtaaat agtctcgttt attcgtccat accaaccagc
      241 aaattgaaac cttttgatta cagcaaagct gatcagaaaa tcaaacaaag ccgggcgata
      301 tcggtgatgt tcagcaaacc gaacgggaaa acctatcagg acatgcttga tgtttttaat
      361 gatcctgagc ttatggaaga attgaatcga ccgatctttt attatccgat cgtttatgat
      421 gtacatgaac tggaacaaaa atataacata cgaacggatg aagtgacatt tattttcttt
      481 gatggaggaa aagaagcaaa tcggataact gcgggtaagg gaggaataac tgattttgat
      541 aaggagttga tccctgaact gaatcgactt ccgttagcca atatcaaaca attagaagaa
      601 gaattggata gaacgggagt aacttcccaa aattccgaga ttgctaattg agacattggc
      661 gcgatgaaac ggtgggtcta tatagcgcta tttttaatta tcagaacaag tgatgtttga
      721 tcttcaaaat aacaaataaa aaattaaaaa atatagttga cgaaattcaa aaattcgatt
      781 agacttaaat caattcttaa ggaaagggtg acctgtaatg aacttatcaa aacgtatttc
      841 agcagaaaac aaaaaaaatt ggcgcagctg gcgtagataa gttgtattaa tggtgagact
      901 ttcccataga tacaactttt tagagtgcat ttctaaagct tgtatctatg ctagacatga
      961 acattgactg ccgcatagat tagaatctat gcggtttttt gtgtaaagac aatgaccgct
     1021 ttggccattg tctttttttg tagactggat acttgcctga ttataataaa taaaaagatt
     1081 gactttgcag gaggaaaaaa atgaaaaaca aacgattaat aacagttgta gtaattattt
     1141 tagtttattt agcaggtgca tttatttatg gaaaagcctc aggcgaaaaa gaaagtactt
     1201 cgacgaacca gacaaaaaaa acaacagttg ttggggtatt gcaatacgtg agccatccgg
     1261 cattagatga gatttatcga ggaatcaaag atggtctgaa agaagaagga ttaaaagaag
     1321 gagaaaatct tgagatcaaa tttcaaaatg gacaagccga tcagagcaag ctagccacaa
     1381 tgagtcaaca gctagtacaa tctgatccag atgccttgat tggaatcgca acacctgccg
     1441 ctcaatcatt agcaaacacg acttcatcga tcccagttgt gttaggtgct gtaacggatc
     1501 ctgtgggggc tggattagtc gcttctttag agaaacctgg tggtaatgta acaggtgttt
     1561 ctgatcagcc gcctgttact tcacaaatca agcttgcttc tgatttgttg ccaaatgcaa
     1621 aaaaagtcgg aatcttgtat gcttcttcag aggataattc aaaataccaa gtagcacaag
     1681 cagaagaagc tgcaaaaaaa gaagggttag aatcagtaaa atatgcggtg ccttccacta
     1741 atgagattgc acaaacggtt caagtgatga gccgacaagt cgattttatc tatgttccat
     1801 tagataatac cattgccaat gcgatgcaaa cagtggtaaa agaagcaaac aaagcaaata
     1861 tccccgtcat tccatctgtg gatacaatgg tggaacaagg tggactagca acaatcggga
     1921 tcaatcaata tcaattaggg cttcaaagcg gtaagatggc ggcagaactt gcgagtggaa
     1981 aagaaaaacc ggaaacgacg cctgtttata catttgatca aggggataca gtgatcaatc
     2041 aatctcaagc tgatcgctta ggaatcattg ttccccaatc gatgaaggaa aaagccaaaa
     2101 tcattacaga tgactcgcag caagaaacat ctaaggagga tgacaaatga tcgtatcagc
     2161 tatttcacaa ggcatgcttt gggcaatatt aggattaggg attttcatga cttatcggat
     2221 cttagacttt cctgatatga cgacagaagg gtccttccca ttaggtgctg ctgtctgtgt
     2281 gacagctatt actcatgggg tagcgccgat tgtagctaca ttattaggcg taggtgctgg
     2341 catgatagca ggactcgtta cggggttact ttatacaaaa ggaaagatac cggttatttt
     2401 agcagggatt ttagtgatgt caggattgaa ctcagttatt ttgtttgtga tgcgaacacc
     2461 aaatctttct ttattgaatc atccgattct acaagacagc ttccatcgct ttgggttacc
     2521 tgattacttt gacacagtcc ttcttggctt catctctttg ggcatcttga ttgctgtact
     2581 gctattcttc ttcaatacag atttgggtca aggctatatt gcgacaggag acaacgaaac
     2641 gatggctcgg tcgttaggga taaaaaccga tcgtatgaaa attttaggtt taactttgtc
     2701 gaacggtgtc attgcattat ccggtgcgct gattgcccag aacgacggat atgcagatgt
     2761 aaataaaggg attggcgtaa tcgtcatcgg tcttgcttcc atcatcatcg gtgaagtgat
     2821 cttccaagaa ttgacgctag cagaaagatt gattgctatt gttgtcggca gtatcattta
     2881 tcagctattg attttagtag taatcaaact agggtttgac acgacttatc tgaagttgtt
     2941 ctccgctatc atcttagcta tttgtctgat gatcccgcaa ttgaagaaag cactgaactt
     3001 aaaaacgggt tttgagaagg aggcatagta atgactgata tattgacaat caaaaatggc
     3061 agaaaagtcg taaacaatgg aatgaatgaa gagaaagtac tattggatga aattaacctt
     3121 acaatcagag aaggggactt catcactgtc cttggcggga atggtgctgg aaaaagcaca
     3181 ctgttcaata cgatcgctgg tacgcttcaa ctcagtcaag gatcgatctc ttttaaagat
     3241 cagctgatca caaaagattc agaagaaaaa agagcacgat tcctttctcg agttttccaa
     3301 gaccccaaga tgggaacggc tcctcggatg acagtagcag aaaatttgct acttgcacaa
     3361 aaaagaggtc aaaaacggaa attccgttta cgtaacttga aaaatcaaaa agaagatttt
     3421 ttcagactat gtcaagaagt cggtaatggc ctagagcaac acttggatac tccagcgggt
     3481 gaattatctg gtggtcaacg ccaagcatta agcttgctga tggcgacgat cacagctcct
     3541 gagttactat tattagatga acatactgca gctttagatc ctaaaacagc taaagcatta
     3601 atgcgattaa caaatcagcg gatcaatgaa caaaaattga cttgtctcat gatcacgcat
     3661 cgaatggaag acgccttgaa atacggaaat cgtctgatcg tactccaaaa agggaaaatc
     3721 gttcaagata tttctgaaaa agaaaagcaa catttgacaa tgggcgacct tttgcagttc
     3781 tttgaagaag tagtggattg atttcgacag aaaaattcct ttcagtagaa ggacttgaaa
     3841 actcattgac atcttccttt gattcatcct atacttaaaa caataaacaa ttaaacatat
     3901 ttgggtgttt tgtaggatca cgtagtcaat gattttaaca attaaataga atattctttg
     3961 ctctgacaag taaacgatga gaaaagaatt tgctactttg ccacctagac gtttcgtact
     4021 ttttcgtatc aaacgctaag tggctttttt tattgaagta agaacaaagg aggaataaga
     4081 tgatttctgg acaaaccaaa ttagctgggc tctttgctga tccggcttct cacagtttat
     4141 ccccattgat gcacaatact gcttttgaag caaacaacat cgatgcggtg tatttagctt
     4201 tccaagtaaa tccaatgaat ttgaagcaag cagtcgaaag tattcgaact tttgatatgt
     4261 taggtgtaaa tctttcgatg ccgaataaaa cagcggttat tccttatctg gatgaggtaa
     4321 gccaggaagc gcaattgatc ggagcagtga atacgatcgt gcacgaaaag ggtcgtttga
     4381 ttggctataa taccgatggt gcgggcttca tgcaatccgt gcaagaagct gggatttcga
     4441 tcaaaaagaa aaaaatgact ctactgggag ctggaggtgc agcaaaggca gtcactgttc
     4501 aagctgcgtt agacggcgct gaggaaatcg tagtttataa acgaaacaac caaacattcg
     4561 ctcaagtaaa agaaacattc gaacaactca gctatcgaac ttcttgtaag ataaaagttc
     4621 gtgactttgc cgatacgcat caattaagaa aagacttgaa agaaagctgt cttctagtca
     4681 atgcaacaga tatcgggatg ggaaagaaaa tcaatcagtc accgctctta gatataagca
     4741 tgatgcatga gaatctagcg gtttttgatt tgatttatgc acctagagaa acacgtttat
     4801 taaaagaagc aaaaaaagta ggagcaaaag gatacaatgg acttggcatg ttgatctacc
     4861 aaggagcaat cgcgtttgaa ttatggacaa aggaaaagat gccgatccat gtgattgaaa
     4921 agctgtttga ttaaaaaagg ataatagata aagatctttt attctcgcat aaacggtctc
     4981 aagaaaagta atcctttatg tatcgaagca tttatttcgt tattttttat taaattatca
     5041 aaaaatgata ggcttttgtc gattggttat cgtatccttt atttatcagt aagaaacgag
     5101 gaggaaccac aatgagtcgg atggatcgct ataaggacat ccataagaag gcgaaacctc
     5161 tgaagcggga tacggggagt atttttgcta gaagagaacg aaaacgaacg cgtatggaaa
     5221 atgaggaaga tgctacccgt atttatgaaa gagagcagca ttcatttgaa catttgaacc
     5281 aatacgagca acagatatac agagatgcac caagagcaga agaacaacaa aaaaataaaa
     5341 aatttttcaa tcggcaaaag aagaacaaac cgttaaaacc tcgaagaaag cgatcgtgga
     5401 aaaaaatcat tctatcgatt ttgcttgttt tgatccttta ttcaggtatc tcatttttta
     5461 ttggtaaata tgtagctgaa catgacacaa gcttagaggc agcgacttca gaaacctttc
     5521 atgggcaaaa agcgacgaat ggtgcgcata atattttgat ccttggaagt gatacacgcg
     5581 gagaagatgc cgggcgagcc gatacgatca tggtcttaca gttggatggt ccttcccata
     5641 agccgaaact gatttctttt atgcgtgaca gcttcgttac gatcccaggg gtaggacaaa
     5701 ataagatcaa ttcagcttat gcatacggag gagccgatct agtgcgtcaa actttagtag
     5761 aaaattttgg aatcgattgt caatactatg cgaaagtcga tttcaaatcg tttgaaaaag
     5821 tgatcgatgc cttattcatg aacggagtga agatcgatgc agaaaaagat ctgaatctgg
     5881 atggtgtaga tattaaaaaa ggggtccaga agatggatgg acatgttctt ttgcagtacg
     5941 cacgtttccg aatggatgaa caaggagact ttggccgtgt cagacgccaa cagcaagtaa
     6001 tgaacgctat tttcagccaa ttgaagaatc cattgaatct gatccgtgca ccttatgcag
     6061 ctggtaaagc tttaggatat acatccacag atgtcactgc ttggttcttg acgaaaaacc
     6121 tcttttcgat tgcacgagga gctggtggca ttgatcgaat aagtgtgcca gtagacggtt
     6181 cgtggaatta tgggcaaagt gattatgctg gcagtattct tgaaattgat aatcaaatga
     6241 atcaatctgc tattacagat tttttgaata aatgatcata aaaaagatca agaagaagct
     6301 gcgcaaggct tttgtcatga atcaatcaaa cgattcactc gtaaaaaacg ctttcttatg
     6361 gtagatttaa ccaagagagg agctgtttac attggatatc tatctgaact tcaaaaatga
     6421 gtcgcgtgaa gccatcgctt tttatgaaaa agtttttcag actgaagcat caggtatcac
     6481 cacatacggt gaaatgcctg gaatagaaca aatgaacttg ccagaagaag caaaaaatct
     6541 aatcacgaat gcacggctga acatttatga tacattagtt atgtttgcag atacgccaga
     6601 aggaattggt cctgaattag ttgtgggaaa taatgtttct ttagtcatcc agacaagaaa
     6661 tgaagaagaa acgaagcgcc tatttgaaag cttagctgag ggtggtaaga ttgagatgcc
     6721 actggatgct gttccgtggg ctcagttgta tgggatggta actgatcgat ttggcatcaa
     6781 ctggcagatt aaccaagagt gacagctaaa gatgaatatt ttctggaaac atcaagcagc
     6841 aaacggatca tcgtttgttt gcttgatgtt tttgtgtcta tttcgactat acggtatctt
     6901 ttttttattg ccagatgcga aaatatgttc cataatagag aagtccgcaa aaaattaagt
     6961 aacggaggtc agaagatgaa gacggtgata ctagctgaaa aaccttcaca agcaaaagcc
     7021 tatgccgaaa ccttccaaca gcaaaagcgg catgaagggt attatgaaat cagcgatcca
     7081 ttgtttgctg gtgaagtaac catcacttat ggttttggac atttggtaga tatggttgct
     7141 ccaggagctt atgaagagcg ttgggcaaaa tggtctttag aaaatttgcc tattttccca
     7201 gaaaccttcc gttacgaagt tccaatggac aaacgtgcac aattttcgat cgtaaaacga
     7261 gaattgcagt cagccgatac catcattatt gcaacagatg gtgatcgaga aggtgaagcc
     7321 atcgcgtggt cgattattcg acaagcaaac gcattttcta aggaaaagaa ctatttacgt
     7381 ttatggatca attctcttga aaaagaagca atctatgaag gttttaagaa tctccaacct
     7441 ggaaagaact attttccaaa atataaagaa gcgcaagcaa ggcagaacgc tgattggctg
     7501 attggaatga atggaagtcc attatatagc ttgctacttc aacgaaaagg gattgatggc
     7561 agtttttctc ttggtcgtgt acaaacaccg acactctata tgatttatca gctgcaagaa
     7621 gaaatcaaac acttcaaaaa agaaacgtac tttgaaggag aaggtttaat tacgacaaac
     7681 aaagggcagt tttctggaaa aatcgtacca aaaaaagcat ttaaaaccca agaagagtta
     7741 acgaaggaaa tagaaaaact tggagcgcat ttaggtaagc aaaacggacg gattcttgaa
     7801 gttacgaaaa aggaaaagag gttgcatagt ccacgtttat tttcgctatc tagtttgcag
     7861 acaaagatga atcagctaat gaaagcaagt gccaaagcta cacttgatgc tgctcaagga
     7921 ttgtacgaaa gcaagtttct aagctatcca agaacggatt ccttttacat tacagaaaat
     7981 gagcatcagt atctggttaa acatctgcaa aattataaaa aatttttagg aatagaagaa
     8041 gtacagacaa ctgagatcaa agcaaagaaa cgatatgtcg atgcgaaaaa agttcaagaa
     8101 catcatgcaa ttattccgac aaagacgatt ccgactcctg cacgctttgc gaagctttcc
     8161 aaattacagc aagcaatcta tttgcaagtt ttgcgcacta ctgtggctat gtttgctgca
     8221 gattatatct acgaagagac gaccgtaatg acgggcgtac agcaattaaa gctaaaaagc
     8281 atcggaaaga tcccattaca gcaaggttgg caggaaatct tacgcatcaa gtcaaaaaag
     8341 aaagaagctc agactcttcc tcctatcgta gaaaatgaag aagcagaagt agaactgaaa
     8401 agtatggaga aagaaacaca acctccaaaa ccctataccg aaggaacgtt gatcacagca
     8461 atgaaaactg cgggaaaaac gctggataat gatgaagcgc aagaaattct caaagaagta
     8521 gaaggaatag ggacagaagc tacacgagcc aatatcattg aaaatcttaa gcagaagcat
     8581 tacatcgaag tcaataaaaa cgaaataact gttacgccaa aaggaatcac tctttgtaag
     8641 gcagtagcca atgaaccatt actgacgagc gcagaaatga ctgcgcgctg ggaagggtac
     8701 ttgagaaaaa ttggtaaaca agaggggaca ccatctgttt ttttagagaa tatcaaaaaa
     8761 ttcatcctac atttattggc agaagttcct aatcaaatcg acaaggtaga cttttcagat
     8821 gagattagcg ggacacgtca gataaaagcg atggagaaga aaaacgatca attaggaaga
     8881 tgtccaaaat gtaaaaaggg aatagtcatt ctttatccta aaatcgctac atgcttgaat
     8941 ccggaatgcg acttcaaatt gtggccaaca gtagctaaaa agaagctgac taaaacgaat
     9001 ctcagagatt tgctttcaaa aggaaagaca agtaaagttg tcaaaggttt tactggtaaa
     9061 aaagggaaat tcgatgcagt tttagtatta aaagaagata tgacaatcgg tttttctttt
     9121 ccatggatcg aaaacagtgg aacaaaagca gttgatggaa acaaagaaac atcaagaaaa
     9181 aataatgaaa acgaagtaga gtaaatgaaa acaatgaaat agcggaatat ttattccgaa
     9241 aagtgagaat ataaatacca ataaaactaa aaaatatcag tgaatcaagc aaaaacgttg
     9301 gggtaggctg attttatata gatagcaagg agttttttta tttgaaaaaa gtgcattcat
     9361 ttttaaatta tcttatggga gcaatcacga ttgtggctgt gtaccaagca tttctaaagt
     9421 atcctgatta cgggacgaag ttgttgtcat tgacgcacaa tcaaacagca tattcaccaa
     9481 cgttgatttt atcgactttg actgcaggag ctaaaagcgc tacttatttt tttcataaaa
     9541 cgacaagcat gctaaagcga aagaaacagc gaaaacaatt gttggtggtg gtagcggcta
     9601 tgatcattat ttattttcta ccagttatta cacaagtatt tcatcaatat tttggttaag
     9661 aatacgagag tttgtgacaa aagtcatgtc acaaactttt ttctttgtca ttttttcgta
     9721 agaaaaagca aaataaaagt atatacattg attaaaagta tatacttgga tataatgtac
     9781 ttactataga atgagaatgg tatagagggt ggcgaaatat gaaaaaaatg aaaaagtata
     9841 aaattagaaa atctggcaat agcgatgtaa caactatccc accagaagta aaagaattca
     9901 tgggtgtgca gacaggtgac gcaatcagtt atgtttttca atctgatggt tctgtacgaa
     9961 tgatcaaagc acaagaagaa cctgatattg attcattagt tgattcgatc atgaatcaat
    10021 atgaagacgc gttaaaagat ttggttgatt tatgaggtat ctttcgacta aagaaattat
    10081 caaaatcaac gcgaaagtta ttttacgtca ctcgccaggc gaaatgatcg gtgtaaaaga
    10141 tgcaaatgca ttagatatgg ccgtcaaaca gccttcacaa gcagtattca atcaagaact
    10201 ctatcctgaa atctatgaaa aagcggcgat tttagcaatt aatttagcta aaaaacatcc
    10261 ttttcataat ggcaataaac gaactgctct tgttgccatg ttgttgtttc ttcaattgaa
    10321 taattgtcca gttgcttttt ctcgtcaaga agctgttgat tttatcataa tgattaccac
    10381 tagttcattg gatttcgatt cactaaagtc caagataacc agttatttac gacaaaccgc
    10441 aataaaatga acgaattaaa aactttattt ctcaattaga tcagcatgtc attaaggaat
    10501 atgctgattt ttttatgttt aatcatacaa aatagttttt tcataaaaat atggaaaata
    10561 tggattaatt ttgaaataat tgatttaaaa ggaatacaaa agagt
//
LOCUS       DADQCX010000090        10510 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.091, whole genome shotgun sequence.
ACCESSION   DADQCX010000090 DADQCX010000000
VERSION     DADQCX010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.091"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(220..972)
                     /gene="xth"
                     /locus_tag="J8R83_002244"
     CDS             complement(220..972)
                     /gene="xth"
                     /locus_tag="J8R83_002244"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAZ9575361.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="J8R83_002245"
     CDS             1085..2005
                     /locus_tag="J8R83_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9575362.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="J8R83_002246"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="J8R83_002246"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAZ9575363.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..4789
                     /locus_tag="J8R83_002247"
     CDS             3311..4789
                     /locus_tag="J8R83_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9575364.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            5066..7126
                     /locus_tag="J8R83_002248"
     CDS             5066..7126
                     /locus_tag="J8R83_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575365.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            7209..7778
                     /locus_tag="J8R83_002249"
     CDS             7209..7778
                     /locus_tag="J8R83_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575366.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(7953..8759)
                     /locus_tag="J8R83_002250"
     CDS             complement(7953..8759)
                     /locus_tag="J8R83_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575367.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            8897..10411
                     /locus_tag="J8R83_002251"
     CDS             8897..10411
                     /locus_tag="J8R83_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAZ9575368.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
BASE COUNT         3726 a         1752 c         2071 g         2961 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagtaaaaa atggtgtaag atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agatgctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa aggatttaaa aattacaata ttgtgattga
     4621 gagtcgaatc acttctcgta cgaatattta tttatctgat tgtttacttg aaaaatttaa
     4681 taaagaacag ataatttgga aaaatccacc gactccagat gactgggaat attttggaaa
     4741 taccatcatc agagaaaaaa atagacattt aactgaaaaa atcagctagt atttatggat
     4801 ggcagctttg tctcacatat ttattagctg atttatgttt ttttcaaaga aaaggtaact
     4861 agatataact agatataact agatatatta cttaacaaaa ttaaaaagta cataagttat
     4921 tattccgatt ttcttgaaac aataaaaaat caaaaaaaat actctcctaa tagtccatct
     4981 tcttttgatt ttatttatat aatgaaatca tcttatgaaa attactactt catgtttaga
     5041 caagagtagg gaggactaag aataaatgtg ttcaaaaaga cgttcaaaac aactaaataa
     5101 acacgcttgt cgtttagata aggaacggtc gtgttctgaa aaacactacg ttaagtttat
     5161 gatgcgcacg atgctgatca gtttatctgt aggtgtctat atgcatgtac ccgttcaggc
     5221 aacgacacaa accatcaagg tcgtacgtac ctctgtttct gagaccactg attcccctat
     5281 cactattact catactttca ctgatgcaaa tggaaaacag ctacttcctg cattgacttc
     5341 ctataataaa gtcagttatc ctccaacgat aaaccactac tggttaattc ctaacaaaac
     5401 attatggaca tcggaaaccg gaagcagtgt gccgctttct atcttttccg atatgactga
     5461 tcctacaaaa ggtgatcagt taaaacagat cactgatatt ttgaatcatg ctttgacaga
     5521 tataaaggac ggtggaagcg cacaagtttc ttatgtatat gaaaaagatt attcacagtt
     5581 tgaaagaaag aaaatcgatg ttctggcagg gacaaaagtt tcgatatctg atctggtaga
     5641 aaggctgaag aacgcagatg gaacacaagg agatatgtcc aaagtaattt caaacaatgg
     5701 gaatatcgtg gatacgacta atacaggaac atctactatt tccttgtcct attttgatcc
     5761 aattgcttta aaaacaatga ctgcatctgc tgtgatccat gttcgtgctg atcaaacagc
     5821 tatcaaagga aaagatcttc acttaagaac aggagagagt tacgccccta aagatcttgt
     5881 tgaatatgta acaaaaagcg atggaacttc aggaaataaa gaagaaatca aaatgaacgg
     5941 gacagtagat actacaactc cgggagaata tcccgttgta ttaacttata tagactcgaa
     6001 aacatcaaat gtggcagaaa caacagctgt agtttatgta gaagcatctg ctgcttcatc
     6061 gactgtcatc actcatttta tagatagtca aacaaataaa gaacttcaag cagaaacaca
     6121 tatgagtagt gtaaatcgta ttcctgattt gcgcctacct gctgaatttt ctgatcgagt
     6181 gccaaatata gatttatcga cttatgaaca aaatgggaaa gtcacttcta tttctgattg
     6241 gatgcaagca aacggattag acagaaaaag tcactggtcg gagatccttg aagtacttca
     6301 ctcagaactg atgaataata ggaagcaatc aggaggggaa attaccttta cttatgttta
     6361 tataccagac aatcgttcat tagaaggtca tgatcttatt gttcatccaa acgaaaaaat
     6421 aaacaaagaa gagttgatcc aatcagcaac aaattcctta ggtaaacccg taccgttaaa
     6481 ggatgtatcg gttacaatca atgaagtacc attggaggat ggttatttga ccaaacaaac
     6541 aggtgatttt acgattatgt atagttatca tgacccgtat tcactccaag aactccatgc
     6601 tcagtcacta ttacatgttt taccattaaa caaacagata gatcaaaaag aacaaaaaag
     6661 acaagaagaa agcttgtcag aaaaaaaaca acaaatggct catgcagttt ctccaacagg
     6721 gaaagtaaaa caaacaagaa gcctagagtt agcaagaata tctagaaaaa tctcagaatc
     6781 taataaaacg ataaggcaag aagctcattt ggccccacaa gtttctggat tggaaaatga
     6841 aattttagag cctaaaataa aacaacaatc agaaaaagaa tttgttgcta aacagtcgga
     6901 agatcagaag gaatcagatg accagaagga aacgaagaaa aaacgcttgt caactattga
     6961 ttccaccgat gagcatctgc agccgcaagt accacttcct agtccgggaa cacccgcacc
     7021 tggtggaggt attccttctt ctgctttagg agatttcatg cgaggtatgg caggaacatg
     7081 ggtatacgct aatcgaaatg aatttgacgc agatgactgg ttctgattta tatctctatc
     7141 tgttatagtc aaataagtag ctgagtcata tgttatttgg cataatggag acgaggaggg
     7201 atagaaaaat gttagataaa acgttacctt acgcagaaat ctggatgaca agaccacttc
     7261 aacaaaatgt tccaatcacg cctttagcgg aaggttttga atttcgattt tatcaaaaag
     7321 aagatgaatc tgcttgggcg gagattgaga cttccgttgg ggaatttcaa acgacagatg
     7381 aagcacttga gtattttcaa caaaactttg ctccttatcc tgaagaactt gaaagaagga
     7441 tgttttttgt agagacaaaa aaaggagaaa aagtagcaac ctgtaccgct tggcgaaaaa
     7501 aatcaagaga gcaagtgtat ccggtttttc attggttagc agtgaaacca gattaccaag
     7561 gaaaagggct cgcaaaagca ttgactgcca gagtcttgca agaatttcct accctccata
     7621 cggacggacc aatctatctt cacacacaga catggagcca tcaggcgatt gctctttata
     7681 aaaaaatggg ttttactttt attgctgaaa atctagacgg cacacctaat ccagattatg
     7741 aaaaagttat gcaggtttta agtaaattag ataaataacg aaatggtgaa ataagtcctc
     7801 agtattggga taaaaaacga aatagtcatt cctcatatct tacttttttg agttaatact
     7861 atcggataac taatggcatg ccatacattc aaaaaagaag gggcagtgac aaaagtattg
     7921 tcactgcccc ttctcttgtt ttttagcatg ttttatcgtt tgattttttt aggaataaaa
     7981 ttcttgatga acgtaaattt ttggtaatcg tttcgactat agaggtaacc aaatacactg
     8041 aaaacaactg ctccaataaa attaacaaat aaatccttca tagtatccat gattcccacg
     8101 tctaagtaac cattttggat gattgtttta tctgttttac catctgcatt ttgactttca
     8161 atgattgtcc gagtgatatc tggaacatga tagacagtgt ttccgtcttt acttaactcc
     8221 acactattga tttgctggat gatcgtatct ttttgcatat cgaattgcag taatttatct
     8281 gctgaaaatt ccacaaactc ccacataaca ccaactgtca tcgaaaaaca gaaggaaaca
     8341 actgctagta ataaaggagt caagttcatg gtttttgtat ttttattgag caaataaaca
     8401 agggaaaagc cgacaccccc agctaaaaat ccgctgaatg catgtagaaa agtatcccac
     8461 attgaaaaat agccataaaa atcacttaac tctcctaaaa ctgttgaact aaaaataaaa
     8521 gataacaaaa tgatttctag catatttgga atctgtatct ttaatatctt ttccagaaaa
     8581 taagggattt caaataaaat taatgtcagt aataaaagca ttgtatttcc ccagtgttgg
     8641 ttccagacct gatccactag cataataacg acgatgatac gtaataaaat atagattccg
     8701 tttgtgattc tacctgcagt ttttgtactg ttcgtaaaaa aggttttcaa atgattcata
     8761 aaataactcc ttcatgtata tccttaatta tactaagaag cgtgtgttta ccaaagctat
     8821 atgacttaaa gaaaaacaga gttgatattg tgaaaaaaat cacttaatat agtataagga
     8881 gaaaaggggg atacaaatga aaaaattagt tgctggttta ttaacagccg ttgcacttct
     8941 tgctatgagc gcatgcggcg cagatcagaa aaatacagcg cagacaagtt ctagtacgaa
     9001 ggaatctgcc gaagtatcat caggcgcttc tgaacaagta tatacagatc caaaagaaat
     9061 gaaagaatct tatgatgtcg tgattattgg agctggtggt gcagggatgg cagcagctat
     9121 cgaagcaaaa gatgctgggt tgaatccagt aattttggaa aagatgcctg ttgccggagg
     9181 aaacacatct aaatcatcaa gcggtatgaa tgcttcagaa acaaaatttc aaaaagaaga
     9241 aggaatcaaa gactcgaatg atgccttcta tgaagaaacg ctaaaaggtg gtggaggaac
     9301 gaatgataaa gaaatgcttc gatactttgt cgatcactct gctgatgcgg tcgattggct
     9361 agatcaaaac ggtatcaaac tggacaactt aacgatcact ggagggatga gtgaaaagag
     9421 gacacatcgt ccgtctgatg gctcggctat tggtggatac ttagtggagg ggttattgaa
     9481 taacgtccat gagcgggaaa tccctatttt tgtcaacgca gatgtgacag acattaagaa
     9541 aaatggggaa acggtcaatg aagtgactgt acatgttcaa ggagaagaac caaaagaggt
     9601 caccggaaaa gcaatcgtag ttaccacagg cggttttggt gccagcaaag aatttattga
     9661 aaaatatcgt cccgatttag ctgattatat tacgacaaat caagaaggat caactggaga
     9721 tggtatcacc atgattgaaa aattaggtgg acaaaccgtt gatatggata aaatacaaat
     9781 tcatccaact gtgcagcagg atgagggggt cttgattggt gaggttgttc gcggagaagg
     9841 agcaatcttg gtcgatcaag aggggaaaag atttgtcaat gaaatggata caagggataa
     9901 agtatctgca gcaattacag cattgcctga aaaatcagct tatttgattt ttgaccaagg
     9961 cgtgcgtgat cgtgccacag ctattgaatt ttatgaccaa aaaggatatg tcacaactgg
    10021 aaagacaatg gaagaattag cagaaaaaat cgatttacca aaagaaacac tagcaaaaac
    10081 agttgatgga tggaatacgg atgttgcgga gaaaaaagat gctcaattca accgtgccac
    10141 agccatggaa catgacttat cgtctccgaa ttattatgcg atcaaaatcg caccaggaat
    10201 ccattacacg atgggcggtg tgaaaatcaa tacgaacact gaagtattag ataaagaaaa
    10261 ccagccaatt agggggttat atgctgctgg tgaagtcaca ggtggcttac atggaaacaa
    10321 ccggatcggt ggaaattcag ttgcggagat cattattttt gggcgacaag cgggcataca
    10381 agcagctcga tttgcttcgg aaaatgaatg aaatagaacg taaataaaaa gaggttgtga
    10441 aatcagcgtt ttgagctaat accgagggtc agctgattga acactgttta gtgaagaggt
    10501 tgtgaaaaag
//
LOCUS       DADQCX010000091        10356 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.092, whole genome shotgun sequence.
ACCESSION   DADQCX010000091 DADQCX010000000
VERSION     DADQCX010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.092"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(22..942)
                     /locus_tag="J8R83_002252"
     CDS             complement(22..942)
                     /locus_tag="J8R83_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9575369.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            1129..1620
                     /locus_tag="J8R83_002253"
     CDS             1129..1620
                     /locus_tag="J8R83_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAZ9575370.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(1644..4019)
                     /locus_tag="J8R83_002254"
     CDS             complement(1644..4019)
                     /locus_tag="J8R83_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAZ9575371.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            4345..4971
                     /locus_tag="J8R83_002255"
     CDS             4345..4971
                     /locus_tag="J8R83_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9575372.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            4994..5698
                     /locus_tag="J8R83_002256"
     CDS             4994..5698
                     /locus_tag="J8R83_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9575373.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            5890..6723
                     /locus_tag="J8R83_002257"
     CDS             5890..6723
                     /locus_tag="J8R83_002257"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAZ9575374.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            6920..8848
                     /locus_tag="J8R83_002258"
     CDS             6920..8848
                     /locus_tag="J8R83_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAZ9575375.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            8986..9441
                     /locus_tag="J8R83_002259"
     CDS             8986..9441
                     /locus_tag="J8R83_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAZ9575376.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            9911..10180
                     /locus_tag="J8R83_002260"
     CDS             9911..10180
                     /locus_tag="J8R83_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575377.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
BASE COUNT         3157 a         1948 c         1924 g         3327 t
ORIGIN      
        1 ttctaaaata aacctgattc ctcatttttt ttgtgaacga ttttttattt ctggcaatac
       61 gccagttgtt cgatacattt tttgttcgtt ttcatttgca aaccggccaa atactgaatg
      121 agttggtaaa atattgataa atgcatcgtc gtcgatttca tgaacgatct gatcaagatc
      181 atacatttcg tagcgggtga tgaccatcat gatcatgttc ccttgttttt ttgaatagcc
      241 accgacagac ggcagtaatg tcattccacg taccatccgt tttgctagtt cttctgttac
      301 ctcttctggc ttgacggtaa cgatcattgc tgttactttt tgatgactcg tgtggatggc
      361 atcaattact tgagtcattg cataaatgga aataatcgta tacaaggcac tttcccagtt
      421 aaagaagaag cctgcgatga ctacaatgat accatttaga atcagcatgt agtttccgac
      481 tgtttttcca gttgtttgtg aaagtacaag agagatgata tccatcccac cagttgtaaa
      541 gcccattttt aaagataatc ctacgccaag acctaataaa acaccgccta ctagggcatt
      601 catcaaaata ttatcagtga tctgtccgac tggaagcagc atcgtcatca ccgatacaca
      661 tacaacattc acaaaactaa ggatcgttgc tcgttttcct actttgagaa accctaatac
      721 aaacacaggg atattcaaaa gaaaaataaa tgttcctgtg tctatcttga tatgaaacca
      781 ttcatataaa agcgaggaaa tgatttgagc gatcccattc atccctgcag aaaagacatt
      841 ggctggaatc aaaaaataat ttaaagcgac cgcagcggtc aatccggtta tcaaaataac
      901 cactattttc tttaatcttt catttttatg atacgcagtc ataattttac tcacaagcac
      961 ctctccccta ctttggtatt ccaaatgtaa gaataacagt ttatctatta aaataaaata
     1021 cttcgaactc aaatgagaag aattttagca aacaggtaag aatctgccct aatcctatga
     1081 taagatagat gtatggtaaa tatttatatg tatatcagga gggttcctat ggcaaaagat
     1141 gctagcttcg acattgtatc agaagtcaat acagaagaag taaaaaatgc gattcagcaa
     1201 acaacaaaag aattgtccaa tcgctttgac ttcaaggatt ctacagtaga aatcaaatta
     1261 gagaacagca atctagttgt attgagcgat gatgatttca aaatcgaaca gatcaaagat
     1321 gtattatttg gtaagctgat caaaagaaat gtgccaatca aaaatatcca tttttccgaa
     1381 tcagaacacg ctctaggtgg caaagctcga caaactgccg atttggtcaa cggaatcgat
     1441 cgtgaaaacg cgaagaaaat cactacagct atcaaaaatg aaaaactgaa agtaaaagca
     1501 caaatccaag aagatcagat tagagtgaca ggtaagaacc gtgatgatct acaagctgtg
     1561 attgctttat tacgtaaact tgacttacca atcgagttgc aattcactaa ctatcgttaa
     1621 tcaaaaaacg aggctgacgt ctgtcattcc tcgttttttt gatttactgc ttcttttgat
     1681 aaccaaaaac gctgtattcc ttcttccaat tccccaacac ttcgtacttc tcttgctgtt
     1741 tgccaatgtt gtgggaataa acgtcgataa gaaaaactag aaaatcgttg atctgccaat
     1801 acaacgattc cttgatccgc catgccacga atcactcgac caccagcttg caagactttg
     1861 ttcattccag gaagctgata agcgtaagca aatccaaggt gttccttctc atcataatat
     1921 gatttgatca gttcctgctc atgattcatc tgcggcaaac ctacacctac gatcatactg
     1981 ccgatcaatc ggtcccctct caaatcgatt ccttctgaaa aaatcccgcc aagtacgcaa
     2041 aatccaatca atgtttcagc gggatttgtt tgaaattttg ttaaaaatcg ttcgcgttct
     2101 tcctcattca tgtccgtttc ttggattagc acattgctgt cgggatattg ctgtctgaat
     2161 gcttccaccg caagatctaa atattgataa gaaggaaaga aaacgaaata attcccgacc
     2221 tttccatcag caaaagcatg aatcgtctct actaattttg ccagactgtg ttcccttttt
     2281 cgataagtcg tctctaggta atttgcgatg aaaacttgct ggtttccttc tgggaaagga
     2341 ctcggcagtt tgtaagccag acttttttgt ccccccagtg tttcctgata ataagagagt
     2401 ggtgaaaaac tagcagaaaa aagaatactg ctttttcctt tatccaacga ctgctcaaga
     2461 aacaagcttg gatcaataca aaactctttt actatcagat cgcgatacgt tttttcgact
     2521 gttgtttcgt agtgatcatc ataaaattca ctgaccttca aaaaatgaag caaatcaaaa
     2581 taataaggaa gcaattgttc ttgtgatggg tgctcaggaa attctgccag ccattcttta
     2641 attttttcgc ttaattgata acctgccttt actaaagatt cagccggtgc tttttgatga
     2701 tgataatccc aatgatcttc ttttgctatt tctcggatcg aatcaaattc ttttaatagt
     2761 ttgttgaaac ggcgatgaag ttttttgaat tcctttggta tagcttcctt acttcgtttc
     2821 gttttttcat aagatagttc tgccgaatac atctctcggg aacgattcac caaattatgt
     2881 gcttcgtcaa tcaaaaacag atagtcctcg tttttttcat cttcaaaaaa acgtcttaaa
     2941 taaacagttg gatcaaataa ataattgtaa tccccaatga ttacgtcaca ccagatactg
     3001 acatctaatg atagttcgaa aggacaaagt gtatgctttc ttgcataagt ttcgatgact
     3061 tcacgagtga tctgattctc atgattcaaa agatcccata aaccttcatt aatccgattg
     3121 taataaccat tggcatatgg gcactgatct ggattacagg tcgtctcatc taaaaagcag
     3181 atcttgtctt tcgccgtcaa agtgacactt tttacttcag ctcctgtatc ttttaatgct
     3241 gtcatagcat cttcagctac ttgtctagtt attgttttag ccgttagata aaagatcttt
     3301 tctccctctt cttcccctac agctttcaaa gcggggaata acgtagagat tgtttttcct
     3361 gttccggtag gtgcttctac aaacaatttc tgtttcgtac ggatcgtttt ataagcagct
     3421 accgctagtt cacgctgacc tttcctatac tcatcatggg ggaatttcaa agccatcaaa
     3481 gaggcattgc gtacagtgcg ccagttttct tgaaaaacaa gccattcttt ataatcttca
     3541 gtcagctttt taaaaaaagt ttctaactgc tctcttgtct gatgttcaac ctttctcgtg
     3601 atcacttctt ctgccgtctg gaagtaagtc aattgcagat ttatttcttg taaatcatgt
     3661 tcttgactat agatataggc atacaccctt gcttgatgaa agaaaagttc cacttgttct
     3721 ggttctaaat cttcaaatcg tggttcggag gttttgattt catctatata ataaataccg
     3781 tctcttttga aaataccgtc tgcacggcct tcaacgatca ggtaatattc atctaattga
     3841 actgttgttt ttaaaaagac ttctttttca tagttttctc ccgcatcttt ttggagcttg
     3901 cggtggattc tcgctccttc taatgcagta tggttacttt ttttacgatt gtcgatactt
     3961 ccacgtcgca aaataaattc tactaagtgc cgcacagata tttttgactg tttgatcatt
     4021 tccaccacct ctttctctct aagattacct gaaaaaacct agtttagcaa aaagagctct
     4081 ctttccaaac ataaaaaaac accctgctga ttaggcaggg atataggata tagaatttgg
     4141 atttttggat gaatctaatg taacaaggac atattaaaat gctatgaaaa cttactttcc
     4201 ttctctttag aatatccaaa tacttttcat atagtctgat aattcagata agtaaagaga
     4261 aataagtacc tgtttttgtt tcctagcaat gaatgcgtta tactaatgga tgaaagaagt
     4321 tttggctatc aaggaggaat gcacatgcat atcgaaagat taaaaacagg aatgattgaa
     4381 gaaaactgtt atttggtcta caacgaagaa gcacttttga tcattgaccc tggagaagat
     4441 gcggaacgaa tcaaacaaga aatcaaaaaa acaaaccaac agccggtagc gattttgctt
     4501 acccatactc actacgatca tatcggtgca gtggaacctt tacgcgcgta ttatcaaatc
     4561 ccagtttatg tcagcccact agagcaaaaa tggctaggtg atccgatttt gaatctttct
     4621 ggactcggta gacatgatga tattgctgat gttattgtct cgcctgcaga atatgaattt
     4681 gaaatgaaaa cttatacttt aggaaacatg tcttttcgcg tcgtccctac cccagggcat
     4741 tctataggaa gcgtcagctt tatttttgat gattttgtcg tttctggcga cgccctgttt
     4801 agaggaagta tcggtagaac cgatctgtat acagggaatt tagaacaatt acttcatagt
     4861 attcggaccc agctgtttgt attacctgat gaatttgcag tctatccagg acatggcgat
     4921 gcaacgacga ttgaacagga aaaaaggaca aatccttttt tcaatcgtta aaacgactta
     4981 ggaggagaat aaaatgacag aaactacact ttatatcgta cgacacggaa aaacgatgtt
     5041 caatacaatt gaacgagtac aaggctggtg tgatacaccc ctcacaaagc aaggacaaga
     5101 aggcattcat tatttaggtc gcgggttaaa aaatgtcgac ttttcatttg cttattctag
     5161 tgacagtggt cgtgcaatcg aaactgcccg tattattcta ggagaacatt ctaagggaaa
     5221 agaaattcct tattttattg aaaaaaggat tagagaatgg tgtttcgggt ctcttgaagg
     5281 tggatatgac atggaaatgt ggggtgtgat ccctcgtgta ttgaatttta aaacatatga
     5341 tgaaatgttt accacagaag tttcttttga acaaattgct aatgctgtat acaacttaga
     5401 taccgctggg tgggcggaaa cttatgaaac attgcgagac cgtgtatgga caggatttga
     5461 agatatcgcc catcactgcg aaaaaaatgg tggtggaaat gttttagtcg tatctcatgg
     5521 tttgacgatc gcctttttgc ttaatctgat cgatcctaaa cagcctgttc gtgctgggct
     5581 tttaaatggc agcgtaacaa aggtcactta tgcaaacggt cgattttcta tccacggcat
     5641 caatgatacg tcttatatcg ataacgggaa aacacatagt cgcgactcgt ttctataatg
     5701 gggatatttt aatttttacc agagaatcat aaaaggcaaa gtctgaacga gggctttgtc
     5761 ttcttttttc tcttcgtgta cttatctgct ttatttctca agtttttctt aatattaaaa
     5821 aacagattgg gtttctcaaa aaataacggt atactataag atgtatctta attgggaagg
     5881 aaggaattta tgttttttgc aaatattatc aaagcagtga ttctcggtat tattgaagga
     5941 ataacggaat gggtgcccat cagtagtact ggtcatttga tcctagcaga tgaattcatc
     6001 aaactggatg ccagttcaca atttatgtcg atgttcaatg tcgttatcca attaggggcg
     6061 atcttggctg tcgtcgttct ttattttcac aagttaaacc cattttctcc aagtaaatca
     6121 acggtagaaa aaaaagatac gtggacactt tggtttaaag tgatcgttgc ttgcatacca
     6181 gccatcatca ttggtttgcc tttggatgat tggttagaag caaatttcca caagttctta
     6241 ccagttgcca ttgttttgat cgtttacggt attgccttta ttattgtcga aaaacgcaac
     6301 aaaaacaaaa cacctcgttg gacttctctg aatgacttta cgtaccaagc agctcttctt
     6361 gttgggttat tccaagtctt ggcacttgtt cccggaacat cccgttctgg cgcaacgatc
     6421 ctaggatcta tcttgattgg tgcttcgcgt tttgtcgcta cagagttttc atttttctta
     6481 gggattcctg tcatgtttgg cgcaagcggc ttgaagatcg tcaaatattt agctgaaggg
     6541 aattcattca aaatggaaga aactgttgtt cttcttgtag gaacattcgt atcttttgtg
     6601 gtttccgtct tagctatcaa attcttacta agctatttga agaaaaacga ctttaccgct
     6661 tttggctggt atcgtattat ccttggtatc attttgattg gttattggtt tattgcaatg
     6721 tagaaaaaac cagaacactt ctcttatttg agaaatgttc tggtttttta ttttctttaa
     6781 taataatcat tataaataat aaaaacaaca tcaagcttaa tcaccaaatg ataaccatta
     6841 tcgttctcat ttagctgtta ttattatcaa ttacattttt attatgctat ccttgttttg
     6901 acaaggaggt ctaataacga tgactaatca gaaaaaagct tttgcagcaa caatcggctg
     6961 ccttttattt atgatcttcg gttttatctt cgaccgattc tctcttacca tcaccccact
     7021 tttttatatc agtgccatta tcatcggtgg atataaacaa acatcggaag gcttgaaaga
     7081 attgtggaat gatcggacac tgaatgtgga tttattgatg gctttagctg ctattggtgc
     7141 ctgtttgatc ggtaattact ttgaaggagc aatgttgaca ttcatctttt gtttaagcgg
     7201 tgcattagag gaatacacaa ctaataaaag tcaaaaagaa attactgctt tgatgaatct
     7261 tcaaccacaa aaagcccaat tattaaaaga aaatggacaa atgcaagaag tagatgtttc
     7321 tcaactaaag gtggataact tggtatttgt cgctaaagga gcagctgttc cgatagatgg
     7381 ctttttagaa agcacacagg caacgatcga tgagtctgca ttaagcggtg aatctgtgcc
     7441 tgtagaaaaa tatttaggcg atgagatgta tgcaggaacg ctgaatcaag gaaatcccat
     7501 cacgattcga gtaacaaaaa cgagttccga aactgtcttt gctaagatta tccaattagt
     7561 agaagaagcg cagaatacgc caactcaaac agcttcattt atcgaacgaa tcgaaaataa
     7621 ttatgtaaaa ttgattttgc ttgctgttcc tctaatgatc cttctccccc actttttcct
     7681 aggttggagt tgggatgaaa gcttttatcg aggaatggta ttattagttg tggcttctcc
     7741 ttgtgcgctt gtcgcatctg ctacaccagc ttctctagct gctctttcaa attctgcaaa
     7801 aaatgggatt ttaatcaaag gcggtatcca tttagaaaag ctttctgaat taaaagcgat
     7861 tgcctttgat aaaacaggaa cgctcactaa aggaaaacca gttgtaactg acagcttttt
     7921 ctttgatgaa aaggatttgg cacaacaact tcttgttgct atggaacaaa aaacgacgca
     7981 tccacttgct catgcgattt tgcaatattt cgattgcaca atacctgaag aaatccaata
     8041 cttaccaata gaagaaatta ctggttttgg attacaaact acctatttag gtgcgcaatg
     8101 gaaagttggc aagcacgcat atgatcctga gacgatgata atcagcaaag agattgcgga
     8161 aatgatcgaa cgtttggaaa atcaaggcaa aaccgtgatt tatctttcta aagatcagca
     8221 gttaattgct gttttaggtc tgctagatat tccaaaagca aatacccaac aagtaatttc
     8281 ctactttaaa tcccaaaaca tccatacaag tatgataacc ggcgaccatt ctggcacagc
     8341 aaaggccatt gctgaacaag tagggattga acattactat gcaagctgta ctccggaaga
     8401 aaaaacacaa ctagtcaaaa aagagaatga actttaccaa gtaaatgcga tggttggtga
     8461 tggagtcaat gatgcgcctg ctttagcagc cgcttcttta ggtgtcgcta tggggcaagg
     8521 gacagatgcc gctatggata tcgcagacat cgtcttaatg aaaagcgact taaataaatt
     8581 tgtctacagt catcggctat ctttaaaaat gcggcggatc atcaaacaaa atattatttt
     8641 ttcgattctt gttattctct tgttgattgc ttctaacttc ctgcaatttt taaatctacc
     8701 tcttggagtt gtaggacacg aaggaagcac aatattggtt attctgaatg gcttgcgttt
     8761 actaagacct ttacctgatc tttctgattc ttcaaaaaaa tgtaagtctt gtccactata
     8821 caaagcgcgg ctgtcttctg tcaaataagc aaagtgtttt tttatgattt tgtttatttt
     8881 atgaaaaaaa cagcttatga ataggtcttg aaggatgaat tcctactttt gtaactttct
     8941 aaaaacatgt tatgattgtt tcgaagaaag tgaggaatat atttcatgga aagttggctt
     9001 tttttaggaa ttattttact tgtagcaatt ttagctaaaa atcaaagtct gatgatagcg
     9061 gcagcttttg ttttgattat gaagctcata ccagcctccc gttccttttt cccttggctt
     9121 caaggcaaag gaatcaatat tggggtgacg atcatcacag cggctattct aatccctatc
     9181 gcaacaggag aaatcggtct acgtgatcta ttagaagcct ttaaatcccc tattggctgg
     9241 gtagctgttt tttgcggtgg gctagtggct gtcttatctt ccaagggtgt aggattgatt
     9301 gcttctgatc cacaaatcac tgttgcactt gttttcggca cgattttagg tgttgtcttc
     9361 ttaagaggaa tcgccgccgg accggtcatt gcttctggta tcacttactg tatcttacaa
     9421 gtatttgctt taggaaaata gaacaaattt tgtctatttt aggagattct taacaccccc
     9481 aatttactga tccgtgatat actgacaacg aggtgataca atgttcgaaa aattaaagta
     9541 tttcatagga acaatcggct ggtttcttct agcggtactt ttgattctgg gcttagctta
     9601 tctattattt cctgatttga tacaaaatgt gtttgatact gctttttgat tgacctatta
     9661 aaacgatata ggggatgctc ctgcgatgca ggggcttttt ttaatcaatg ttttgtaata
     9721 atttaggccg tgccaatgag acttcctata gaattcgatg ctcttttttc tttttggctc
     9781 ttctgctctt ttttgttata ctagattaca gtggacaaaa gaaagaatga tcgcatccac
     9841 ttcaacgaat atcaaaatgg aagaattagt gcctgttttc aggttacttt gaaaagaaag
     9901 gaagacgctt gtggaaactt ttgaaggtct tttaattgat acgtacgttt tacaagaaca
     9961 gccaatgatg ctgactggga tcaacttgca gcttgaggac cgtgtgatca atggcctgct
    10021 taaagatcgc tatttggcaa aatatatctt acgtttgccc ctaaataaat atgtgctgga
    10081 agtaagtggc aaatggaacc gtcggaacca gttggtcata aaaaaaatgt tgataaaaaa
    10141 tatcgatgaa tacattaaaa taatcggtac accagaatag cctttactga tcaaaggata
    10201 ctggttataa aataactgca gtttcttaat agaaaaacaa agaacaacag ggaatcgtat
    10261 cccttttcaa aaaaaacttt gcaaacggtt ctctttgtta tataataact tagtaccaaa
    10321 cattcccatt caaactttgt ttaaatagat aaataa
//
LOCUS       DADQCX010000092        10332 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.093, whole genome shotgun sequence.
ACCESSION   DADQCX010000092 DADQCX010000000
VERSION     DADQCX010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.093"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..305
                     /locus_tag="J8R83_002261"
     CDS             6..305
                     /locus_tag="J8R83_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9575378.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="J8R83_002262"
     CDS             378..1739
                     /locus_tag="J8R83_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAZ9575379.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="J8R83_002263"
     CDS             1761..2021
                     /locus_tag="J8R83_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575380.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="J8R83_002264"
     CDS             2035..2787
                     /locus_tag="J8R83_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAZ9575381.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="J8R83_002265"
     CDS             complement(2881..3486)
                     /locus_tag="J8R83_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575382.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="J8R83_002266"
     CDS             complement(3539..4513)
                     /locus_tag="J8R83_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAZ9575383.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="J8R83_002267"
     CDS             complement(4891..5670)
                     /locus_tag="J8R83_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9575384.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="J8R83_002268"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="J8R83_002268"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAZ9575385.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="J8R83_002269"
     CDS             7161..8558
                     /locus_tag="J8R83_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9575386.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDFFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="J8R83_002270"
     CDS             8639..9079
                     /locus_tag="J8R83_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9575387.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="J8R83_002271"
     CDS             9227..9553
                     /locus_tag="J8R83_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9575388.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="J8R83_002272"
     CDS             9554..10303
                     /locus_tag="J8R83_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575389.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
BASE COUNT         3277 a         1822 c         2141 g         3092 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaaaatta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag atttttttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct at
//
LOCUS       DADQCX010000093         9954 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.094, whole genome shotgun sequence.
ACCESSION   DADQCX010000093 DADQCX010000000
VERSION     DADQCX010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.094"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..657)
                     /locus_tag="J8R83_002273"
                     /pseudo
     CDS             complement(1..657)
                     /locus_tag="J8R83_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(662..1429)
                     /locus_tag="J8R83_002274"
     CDS             complement(662..1429)
                     /locus_tag="J8R83_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9575390.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1917..2342
                     /gene="lacA"
                     /locus_tag="J8R83_002275"
     CDS             1917..2342
                     /gene="lacA"
                     /locus_tag="J8R83_002275"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HAZ9575391.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2359..2874
                     /gene="lacB"
                     /locus_tag="J8R83_002276"
     CDS             2359..2874
                     /gene="lacB"
                     /locus_tag="J8R83_002276"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HAZ9575392.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2885..3817
                     /gene="lacC"
                     /locus_tag="J8R83_002277"
     CDS             2885..3817
                     /gene="lacC"
                     /locus_tag="J8R83_002277"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HAZ9575393.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3820..4800
                     /gene="lacD"
                     /locus_tag="J8R83_002278"
     CDS             3820..4800
                     /gene="lacD"
                     /locus_tag="J8R83_002278"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAZ9575394.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4828..5145
                     /locus_tag="J8R83_002279"
     CDS             4828..5145
                     /locus_tag="J8R83_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9575395.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5145..6851
                     /locus_tag="J8R83_002280"
     CDS             5145..6851
                     /locus_tag="J8R83_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9575396.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            6993..8399
                     /gene="lacG"
                     /locus_tag="J8R83_002281"
     CDS             6993..8399
                     /gene="lacG"
                     /locus_tag="J8R83_002281"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAZ9575397.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8422..8694
                     /locus_tag="J8R83_002282"
     CDS             8422..8694
                     /locus_tag="J8R83_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HAZ9575398.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8715..9614
                     /locus_tag="J8R83_002283"
     CDS             8715..9614
                     /locus_tag="J8R83_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAZ9575399.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3138 a         1678 c         1996 g         3142 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagtagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttc gtgtatttag gaaaagcaac atcagaccaa catctgaaac gtttgtaaat
      541 gttatctatt tgttggatat caatcgttgg aaaacatttc tcaacgctac ttttaaaggg
      601 gagttgatgg tcataaagag tgtcatcaag gtcaaaaaca atatttttat aagtcataat
      661 tctagtccgc ttttaaaata gtagtgtact ggctaaattc ctctaagtgt tgagggctaa
      721 tctggttatc tgtaatgatg gtatcgagtt gatctagatt atagaagtta aagaaatcgt
      781 atcgatcgaa tttagtactg tctactaata agaatttttc tacagcattg tttagggcaa
      841 gttgttgaat cacaccttcc ttgtcactat atgtagcaat agaattatgg gtaacagcat
      901 ttgcactaac aaaagctttg gcaaatctaa ttgcttttaa atttgtcgaa gccattgaac
      961 ctacaaaagc tccagttatt tctctatatt caccgccaag aagcaataaa tcaatggttt
     1021 cgctatcatt tagaatcaag aacacaggga gactatttgt aatgacacga attttataac
     1081 ctttacgacc tttcaattct aatgccagtt gttcaagtgt agttccgggt ccaataaaaa
     1141 tagtatcgcc atctttgatt aaagagcagg cttttttagc aatgtcaatt ttttcttttg
     1201 tatttagact tttcttctcg atatgtgtct tttcaagtgg ctttttagag gaaagtaatt
     1261 gtgcaccacc atgagtacgt gttaaaagtc catcagcttc tagagcatca aggtctctac
     1321 gggctgtcat atcggaaata tctagttcat ctattatttc ttttatggtt atggtcccat
     1381 caatctttaa catatctaaa attttttcta atcgtcgttt tttgttcata tgaagaccct
     1441 tctttcataa agtaattttt ttccaaagat aattctcttt taattgtatc ataaaagaca
     1501 atattttcaa ggtaaaacaa acaatttcaa acaaaaacaa atgttagatg atgaaataag
     1561 aacagtggat tgacgtatat tagcttaggt cagattttgt ataagacgaa aataaagtag
     1621 gacctcttaa tcagtaagtt atagaaagta aaagactttt gtaatacttg aatagatatt
     1681 tcacgtccat tttgtgatgg attaaatgaa caaaaatgaa caataattta acggtgttat
     1741 ctatttttta aaaaaacaaa taaaaaaaca aaaaataaac aaaaaagtgt tgctttttgt
     1801 ttgaatgctt gatattatat aaacaaagaa atgatgaaaa cgttttttcg aacattttgc
     1861 aaaatgtttt ctacttctac gtagcatttc tttctaaaat ttaggaggtg gtcaaaatgg
     1921 ctattgttgt tggtgcagat ctcaaaggta cgagattaaa agatgttgtg aaaaattttc
     1981 ttgtagaaga aggttttgag gtaattgatg tgactaagga cggacaagat tttgttgatg
     2041 ttaccttggc agttgcctct gaagtaaata aagatgagca aaacttaggt attgtaattg
     2101 atgcttatgg agctggtcca ttcatggtag caactaaaat taaaggtatg gttgcagcag
     2161 aagtttcaga tgaacgctca gcttatatga cacgtggaca taacaattca cgaatgatta
     2221 cggttggcgc tgaaatcgtc ggtgatgagc ttgctaaaaa catcgctaaa ggtttcgtca
     2281 atggtaaata tgatggcgga cgtcatcaaa tccgagtaga tatgcttaac aaaatgtgtt
     2341 aaggaaagga gttaaggaat gagaatcgca attggatgtg accacattgt cacagatgaa
     2401 aaaatggcag tatcagaatt cttgaaatca aaaggacatg aggtccttga tttcgggaca
     2461 tatgaccacg cacgtactca ctaccctatc tatggtaaaa aagtcggtga agcagtagta
     2521 agtggtcaag cagacttggg agtatgtatc tgtggtacag gtgtcggcat taacaatgca
     2581 gtcaataaag ttccaggtgt tcgctcagcg ttggttcgtg atatgacatc agctatatat
     2641 gcaaaagaag agttaaatgc gaatgttatc ggtttcggtg gaaagattac tggtggtctt
     2701 cttatgaatg acatcattga agctttcatt gaagctgagt acaaaccaac agaagaaaat
     2761 aaaaaattga ttgcaaaaat cgaacacgtt gaaacacata atgcacatca agcagatgaa
     2821 gatttcttta cagaattcct tgaaagatgg gaccgtggtg actaccacga ttaaggtata
     2881 acaaatgatt ctgacagtca cactaaatcc ttcagtagac atctcttatc ctctagaaac
     2941 attgaaaatt gatacagtga atagggtgaa agatgttagt aagacagctg gtggaaaagg
     3001 cttaaatgtt actagagtct tgtatgaatc tggtgataaa gttactgcta caggtttctt
     3061 aggtggtaaa attggtgaat ttattgaaag cgaattagaa caatctcctg ttagtccagc
     3121 tttttataaa atctcaggaa acactagaaa ctgtattgct atcttacacg agggtaacca
     3181 aacagaaatt ttggaacaag gaccaacagt ttctcatgaa gaagcagaag gttttcttga
     3241 ccactatagc aatcttatta aacaatcaga agttgtgaca atttcaggaa gtttaccttc
     3301 aggacttccc aacgattatt atgaaaaact tatccaactt gcttcggatg aaggagtagc
     3361 agtcgttttg gattgttcag gtgcacctct tgaaacagtt ctaaaatcgt cggctaaacc
     3421 tactgccatc aaacctaata atgaggaact ttcacagttg cttggaaaag aagtaacaaa
     3481 agatattgaa gaactcaaag acgttcttaa agagtcactt tttagtggta tcgaatggat
     3541 agtggtctca ttaggtcgaa acggtgcctt tgcaaaacat ggtgatgttt tctataaggt
     3601 agatattcct gatatcccag ttgttaatcc agtcggatca ggggactcaa cggtagctgg
     3661 tattgcatca gctttaaata gtaaaaaaag tgacgctgac ttattaaaac atgcgatgac
     3721 attgggtatg ttaaatgctc aagaaacaat gacagggcat gtgaatatga ctaattacga
     3781 aacactaaac tcacaaattg gagtaaaaga ggtataaaaa tggtacttac agaacagaaa
     3841 cgcaaatctt tggaaaaaat ttcagataaa aacggtgtta tctcagcttt ggcatttgac
     3901 caacgtggtg ctttgaaacg tttgatggca cagtatcaag atacagaacc aactgtagct
     3961 caaatggaag aactaaaggt tttggttgct gatgaactta caaaatacgc ttcttcaatg
     4021 ttgcttgacc ctgaatatgg acttccagca acaaaagcat tggataaaga agcaggtctt
     4081 cttcttgcct atgaaaaaac aggttatgat acatcaagta caaaacgttt gcctgactgc
     4141 ttggatgttt ggtctgcaaa acgtatcaaa gagcaaggcg ctgatgccgt taagttcttg
     4201 ctttactatg atgtagacag ctcagatgaa cttaaccaac aaaaacaagc ttatattgaa
     4261 cgtgttggtt ctgaatgtgt cgctgaagat attcctttct tcttggaaat ccttgcttat
     4321 gatgaagaaa tctcagatgc aggttctgtt gaatatgcaa aagtgaaacc tcgcaaagtc
     4381 attgaagcga tgaaagtttt ctctgatcca cgctttaaca ttgatgttct taaagtagaa
     4441 gtaccagtta acgttaaata tgtcgaaggt tttgctgatg gtgaagtggt ttacagtaaa
     4501 gctgaagctg ctgacttctt taaagcacaa gaagaagcga ctaaccttcc atacatctac
     4561 ctaagtgcag gtgtatctgc taaattgttc caagaaacat tgcaatttgc tcacgactca
     4621 ggtgccaagt ttaatggtgt gctttgtgga cgtgctactt gggcaggatc tgtagaacct
     4681 tacatcaaag aaggtgaaaa agcagcacgt gaatggttgc gtactactgg attcgaaaat
     4741 attgatgaac ttaacaaagt tcttgttaaa acagctagtc catggactga taaagtatag
     4801 taaaaacata aaacggagga tattgttatg aacagagaag agatgactct cttagggttt
     4861 gaaattgttg cttatgctgg agatgctcgc tctaaacttt tagaagcgct taaagcggct
     4921 gaaaatggtg atttcgctaa ggcagatagt cttgtagtag aagcaggaag ctgtattgca
     4981 gaggctcaca attctcagac agctatgttg gctcgagaag cttctgggga ggaacttcca
     5041 tacagcgtta ccatgatgca tggtcaggac cacttaatga ctactgtctt attaaaagat
     5101 gtgattcatc acctcatcga actttataaa agaggagcaa aataatgcat aaactcattg
     5161 aacttattga gaaagggaaa ccgttctttg agaaaatctc tcgaaacatc tatcttcgtg
     5221 ctattcgtga tggatttatc gctggtatgc cagtcatcct tttctcatct atctttatcc
     5281 ttattgccta tgtcccaaat gcttggggat tccactggtc aaaagacatt gagaccttct
     5341 tgatgactcc ttatagctat tcgatgggta tcctagcatt ctttgttggt ggtactaccg
     5401 ctaaagcttt gacggactca atgaaccgtg acctacctgc gaccaatcag attaacttct
     5461 tatctacgat gctagcgtct atggtagggt tccttttgat ggcagctgag cctgcaaaag
     5521 aaggaggctt cttgacagcc ttcacgggaa caaaaggtct tttgacagca tttattgcag
     5581 cctttgtgac agttaatgtt tacaaggtct gtgtgaaaaa taatgttact attcgtatgc
     5641 ctgaagaggt tccaccaaat atctctcaag tatttaaaga cttgattcca ttcactgtag
     5701 cggttgttct cctttatgga tttgaactca ttgttaaggg aactcttggt gtaaccgttg
     5761 cagaatcaat cggtaccgtt cttgctcctc tcttctcagc tgcagatggt taccttggaa
     5821 ttacacttat ctttggtgct tatgccttct tctggtttgt tggtatccac ggtccttcaa
     5881 ttgtcgaacc agcaatcgct gctatcactt atgccaatat cgatgccaac ttgcatctta
     5941 tccaagctgg acaacatgca gataaagtta tcacttctgg tactcaaatg tttattgtta
     6001 ccatgggtgg aacaggagct acattgattg ttccattctt gttcatgtgg atttgtaaat
     6061 cagaacgtaa ccgtgccatc ggacgtgcct cagttgttcc aacattcttt ggggttaatg
     6121 agccaatctt atttggtgca ccaatcgtat tgaatccgat tttctttgta ccgttcattt
     6181 tcgctccgat tgtcaacgtt tggatcttta aattctttgt tgacacattg aacatgaact
     6241 cattctctgc caaccttcca tgggttactc ctggtccgtt gggaattgta ctcggtacta
     6301 acttccaagt tctatcattt atcttagccg gactcttggt agttgttgat actatcattt
     6361 attacccatt tgttaaggta tacgatgaac aaattcttga agaagaacgt tctggtaaaa
     6421 caaacgatgc tcttaaagaa aaagtagctg caaacttcaa tactgctaaa gcagatgccg
     6481 ttcttggaaa agcaggcgtt gctaaagaag atgtagcagc aaacaataat atcacaaaag
     6541 aaactaatgt ccttgttctt tgtgcaggtg gaggtacaag tggcttgctt gccaatgcct
     6601 tgaacaaagc agcagcagaa tacaatgttc cagtcaaagc ggcagcgggt agttacggtg
     6661 ctcaccgtga aatgttgcca gagtttgact tggttatctt ggctccacag gtcgcttcaa
     6721 acttcgatga tatgaaggct gaaacggata aattgggcat taaacttgca aaaactgaag
     6781 gagctcaata tatcaaattg acacgtgatg gacaaggtgc tcttgcattt gttcaacaac
     6841 agtttgatta ataaatttgt aaaagttatt tgagacgaga ttattctttc agttccttat
     6901 aatattgtta accatatcat tgcatttcat ttccttggtt tccggaactc agaatatcgt
     6961 ctcaaatgct ttttttgaaa ggatttatag ttatgactaa aacacttcct aaagatttta
     7021 tttttggtgg tgctacagct gcttatcaag cagaaggtgc gactcacacg gatggtaaag
     7081 gcccagttgc atgggataag tatcttgaag acaattattg gtacacagca gagcctgcaa
     7141 gtgattttta ccataaatat cctgttgatt tagaattagc tgaaaaatat ggcgttaatg
     7201 gtattcgtat ttcaattgcc tggtctcgta ttttcccaac tggctatggc gaagtaaatg
     7261 aaaaaggtgt tgaattctac cataatcttt ttgccgagtg ccacaaacgt catgttgagc
     7321 cattcgtgac tttgcaccac tttgacacac cagaagttct tcactcagat ggagatttct
     7381 taaaccgcga aaatatagaa cactttgtag attatgccgc tttctgtttt gaagagttcc
     7441 cagaagtaaa ctactggaca actttcaatg aaattggccc aattggagat ggtcaatact
     7501 tggttggtaa attccctcca ggcattcaat atgatcttgc caaagtcttc caatcacacc
     7561 acaatatgat ggtttctcat gcacgtgctg tgaaattgta taaagataaa ggttataaag
     7621 gcgaaattgg tgtagtacat gcgttgccaa ccaaataccc ttatgatcca gaaaatccag
     7681 cagatgttcg tgccgctgag ttagaagata tcatccataa caaatttatc ttggatgcaa
     7741 cctaccttgg acactattca gataaaacga tggaaggggt caaccacatc ctagctgaaa
     7801 atggtggaga acttgatctt cgtgatgaag acttccaagc acttgaagca gctaaagatt
     7861 tgaacgattt ccttggtatc aactactaca tgagtgattg gatgcaagcc tttgatggtg
     7921 agactgaaat cattcacaat ggtaagggtg aaaaaggaag ttctaagtac cagattaaag
     7981 gtgttggtcg ccgaatcgca ccagattatg tgcctagaac ggattgggac tggattattt
     8041 atcctgaagg cttgtatgac caaatcatgc gagtgaaaaa tgattatcca aactacaaga
     8101 agatttacat cactgaaaac ggtcttggat acaaagatga gtttgtagat aataccgttt
     8161 atgatgatgg tcgtattgat tacgtgaaga aacacttgga agttttatca gacgcaattg
     8221 cggatggtgc aaatgttaaa ggttacttca tctggtcact tatggatgtc ttctcatggt
     8281 caaacggata cgaaaaacgt tatggactat tctatgtaga ctttgacacg caagaacgct
     8341 atcctaagaa atcagctcat tggtataaga aagtagcaga aactcaagtg atagagtaat
     8401 attacttgaa aatgtaaaaa attgttatcc gatactttag aaaaagtaca acacttattt
     8461 agaccaggct ttgaaaaggt atatattgtt agtttcgaag attgtcctat gattcctgag
     8521 cttgaagcta ccccgttgct aaaatgtggt aaatggtatg tttcaactgg aaaagagtgg
     8581 atttgccatt ctgatttaga gttatcagca tttgaatggg aatttttaca atcactcgat
     8641 gtagaaatac gtgagactat tcacttcgag gtaaattatt tgcctttcca ataataaaaa
     8701 gaaaggaatt agttgtgact atcgaattaa aaaacgagta tcttactgtt cagtttaaaa
     8761 cacttggtgg tcaactgact tcgattaaag acaaggatgg gatagagtat ctctggcaag
     8821 ctgatccaaa ttattggaat ggacaggcgc ctattctatt tcctatctgt ggtagtttac
     8881 gaaatgattg ggctatttat agacctcaag aaagaccttt ttttacaggt cttattcgta
     8941 gacatggttt tgttcgaaaa gaagaattta ttctggaaga agtcaatgat aatagcgtga
     9001 cctttagtat taaaccaaat gctgagatgc ttgataatta cctatatcag tttgaactga
     9061 gagttgttta taccttgaat ggtaaatcaa ttagaaccga atttcaggta acgaacttgg
     9121 aaatggaaaa aacaatgcct tactttattg gagcccatcc agcattcaat agtcctttag
     9181 tagaaggtga aaactatgag gattattata ttgaatttag tgaggttgag tcttgctcga
     9241 taccaaagag ttttcctgag acaggattat tagatttgca agatcggaca ccttttttgg
     9301 aaaatcaaaa aattctcgat ttggactact cacttttttc ccatgatgcc attacacttg
     9361 accagctcaa gtctcgtagc gtaacgcttc ggtcaaggaa gtctggtaaa ggtcttcgag
     9421 tagattttga tgattttccg aacttgattc tgtggtctac aactaataaa agtccattca
     9481 ttgctttgga accttggagt ggtctctcca cttcacttga agaaggtaat ttcttagaag
     9541 ataaaagaca ggtaacgaaa atttcacctc aagaaacttc tagaaaaatc tatgatatta
     9601 ctatccttaa ttaaaatttg ttattatttg agtcttcaat aagatttgaa tactcttacc
     9661 ttgtgatgat agattggtct tctccgtgcc agtcttacat cgcaaggttt ttaagttttt
     9721 tgtgggtcta tgtcaactgt agtgggtgac gaaaagctaa tatctaaaga cagtctggta
     9781 gtaaaaaata agattattta ctacttcttg atttaaaata atagtggagc cattaatttg
     9841 tggcaaattt aatttaatat tttgcctcaa attagccaca ctttttatag aactaagagg
     9901 aaaaatgaaa ttttcttcct attaatatag ttgtttgaaa tcttaaatat agcg
//
LOCUS       DADQCX010000094         9853 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.095, whole genome shotgun sequence.
ACCESSION   DADQCX010000094 DADQCX010000000
VERSION     DADQCX010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.095"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(241..1089)
                     /locus_tag="J8R83_002284"
     CDS             complement(241..1089)
                     /locus_tag="J8R83_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9575400.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1252..2154
                     /gene="gnd"
                     /locus_tag="J8R83_002285"
     CDS             1252..2154
                     /gene="gnd"
                     /locus_tag="J8R83_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAZ9575401.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2156..3157
                     /locus_tag="J8R83_002286"
     CDS             2156..3157
                     /locus_tag="J8R83_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAZ9575402.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3154..3438
                     /locus_tag="J8R83_002287"
     CDS             3154..3438
                     /locus_tag="J8R83_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9575403.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3471..4268
                     /locus_tag="J8R83_002288"
     CDS             3471..4268
                     /locus_tag="J8R83_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9575404.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4282..5115
                     /locus_tag="J8R83_002289"
     CDS             4282..5115
                     /locus_tag="J8R83_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9575405.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5133..5990
                     /locus_tag="J8R83_002290"
     CDS             5133..5990
                     /locus_tag="J8R83_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9575406.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6012..6521
                     /locus_tag="J8R83_002291"
     CDS             6012..6521
                     /locus_tag="J8R83_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9575407.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6558..6959
                     /locus_tag="J8R83_002292"
     CDS             6558..6959
                     /locus_tag="J8R83_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575408.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7071..7424
                     /locus_tag="J8R83_002293"
     CDS             7071..7424
                     /locus_tag="J8R83_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575409.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7458..7901
                     /locus_tag="J8R83_002294"
     CDS             7458..7901
                     /locus_tag="J8R83_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAZ9575410.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7918..9003
                     /gene="uxuA"
                     /locus_tag="J8R83_002295"
     CDS             7918..9003
                     /gene="uxuA"
                     /locus_tag="J8R83_002295"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAZ9575411.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8996..9709
                     /locus_tag="J8R83_002296"
     CDS             8996..9709
                     /locus_tag="J8R83_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9575412.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         3285 a         1557 c         2170 g         2841 t
ORIGIN      
        1 aaaaataata aaaaaaagaa aagataaatt ttttactact gtatactaac tttgttatcg
       61 catctaacaa gtaactcgaa taataccaat acaaccttct ccaaagatgc gatgacatac
      121 gttctaaccc accgactatt gatgttctgt accacccttg cagaaccaaa aaagccacta
      181 ccaaatattt ggtagtggct ttttttgttt tatggatttt tcgctttttc tgttatggtg
      241 ctattctttg atttcagaaa tagtatgtcg aactttagcg atagaacgac gtgattcttt
      301 ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa atgcttagtt gagaaatacg
      361 ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa atagaaataa aaacgacatc
      421 gccaagttta gcaagggaag aattagcttg gctagtaata acgattgttt ttgctccagt
      481 ttttcttacg gtttcagcaa tatggattgt ttcttttgat tgccctgtgt gagaaatcaa
      541 aacagcacag tctttttccg tcaataaaga agcttccatc aattgaatat ggtaatccgt
      601 gctgtgagaa gttgcgatag gggaacgcaa aaatttatga taagcgtcag ttgctacaat
      661 ctctgaaccg ccaacaccga aaaaatagac acgtttagat tcattgataa tagtagccgc
      721 tttttttaga tccttttgtt gtaacaactt ttttgtgtca tttaaagttg aaatactaga
      781 ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt ttctgaatat tttcgtggat
      841 agaaatagca gatagatcat tttcttggat caacatggcc attttaaaat ctttaaatcc
      901 attataacca agtttttttg taaattgaaa aaaagtagag tcagcaatgc ccagttcact
      961 tgctaaattg ctaataggac tatgacttac tttgcttgga ttttctaaaa tataatcggc
     1021 gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt ttgatttgta gtcttatgga
     1081 gacgctcatg agaattcctc attttcataa taagattatc attttttccg ttctcattaa
     1141 tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa aatatttttg taaaatctat
     1201 ttacaaaaaa attttttgta taatgagggt ataagaaatg gaggcgctat catggaaatt
     1261 ggtgtaattg gtttgggaaa aatgggattg aatttagctt taaacttaaa agagcaccat
     1321 cacaaagtac aaggactcga catttcaagt acagctgtta gtcaggcaag agaaaatgac
     1381 attcctgctt atcaagagat ctctgaattt ctagctactt ttgagcagaa aaaaatcatc
     1441 tggttaatgc ttcctgctgg agagataacc gaaaacatgt taagaaaact ttttccaaaa
     1501 ctcggaccag gagacattat tattgaaggc ggaaactctt attataaaga ttcaatccgt
     1561 cgagcagaag agtttcagaa aaatgaaatc ggttacttgg attgtgggac ttctggagga
     1621 atcgaaggag cacgacatca agcctgctta atgattggag gagataaaga aacttttcta
     1681 tccgtggaac aattattcaa agatgtagca attgaaagag gatatctgta tgctggtgca
     1741 tccggaagcg gacacttctt gaaaatgatc cataatggaa tcgaatatgg aatgatgcaa
     1801 gcaatcggtg aaggattcca acttgtacaa aaaagtgagt atgcttttga cttggaacaa
     1861 gtcgcacgtg tttggaatca tggttcggtg attcgcggct ggctgatgga aatcatggaa
     1921 gatcagttaa acgaacatcc caatttaagt aattatcggg gaatcgtttc tgcatcaggt
     1981 gaagcaaaat ggacggttga aacagcgcta gaaatggctg ttccagttcc agtaattgca
     2041 actagtttgt tcatgaggaa tctttcacag gaagaagata gtttttcagc aaaagtagtt
     2101 tcagcactaa gaaatgggtt tggcggacat gaaatagttg aaaagggtga gtaaaatgcc
     2161 agattatcat atagcaatcg ttaattccag cagtttcgga agagtctttc cacaccactt
     2221 ggaaagatta aagtcagttg gagacgttca tttctttact gttgatcaag agattccagg
     2281 aaaagaacta gcggagttac ttaaaggatt caatatcatt attgcaagtg ttacgccatt
     2341 ttttcgacga gatttttttg aaaacaaaga tgaactgcta ttgatttccc gacatggtat
     2401 tggttacaac aatattgatt taaaagcagc aaaagaacac cagacaatcg tatctatcat
     2461 acctgcttta gttgaacgaa atgctgtagc agaaaataat ataactaatt tgttgtccat
     2521 gcttcgacgc acgacacaag cacaagcaag agtcaaggac gatcgatggg aagatcgggc
     2581 ggagttcgtc ggtaggacgc tgtttaacaa aacagttggt gtgattggtg caggaaatac
     2641 cggaagcgga gtaatcgaaa ttttgcgtaa cggttttcgc tgtgatgttc tagcttatga
     2701 tccttacaaa tcagatttat acatcgaaag ctttggtgca aaaaaagtag aacttcaaga
     2761 attactggaa caatcagata tcatttgttt atgtgcgaat ttgacagaag agaactatca
     2821 catgatttct gataaagaag tcgatcagat gaaagaaaat gtttatctat ctaatagtgc
     2881 aagaggcgct ctagttgatg aagaagcgat gattaatggt ctgaaaagcg gaaagatcgc
     2941 aggatatgcc acagatgttt tagaagaaga accgggacgt caagatcatc cgtatttagc
     3001 gtttgaacaa gtagtgatta cgccacatat atcggcctac acaagggaat gtttagaagc
     3061 aatgggtgaa aaatgtgtca gagatgtcga acagatcagt cagcaccttc ttcctgaacg
     3121 ttctgtccag acaaagagca actatataaa aggatgatga agaaaatggt gaacggttta
     3181 aaagtgaaaa caggccctca attttattta tatgaagaag gtggtatttc aaaagtttct
     3241 gatctcttga aatcatacgg cgcgaaaaga gtactggtca cccacggaac ggtatcatgg
     3301 gaaaaggcgc tacctaaatt agtatttttg aatgacgaaa cgattcaatt tttttatcat
     3361 cgttattctg gagaatgtag ttatgctgaa gccagacgaa tagctacaat catcaaaaaa
     3421 atgaaatcga tttcgtagtt ggcgttggcg gaggaaaact gaccgatcta gtgggttata
     3481 gtgccaatct tgcaagaatc gatttcggag tcatccctac tttagctagt aattgtgctc
     3541 catggacacc tcttgctgtc atgtataagg agaatggaca agcagaaggg aaaacagaac
     3601 acttttacag acaagctgct ttttttataa cagatcccca attagtgatt gattcccctg
     3661 ttccatattt cattgccggg ttagcagata cactagcaaa atggtatgaa tctgagctca
     3721 tcttagaaca agattttttg caagatgaat catttttgaa gctagcacaa gatactgcga
     3781 agatctgcaa agaagagatt ttgaatcatt ctgctaaagc aatccaagat atggcacaaa
     3841 gaaaactgac atcggagttc aaacagcttt cagagattat ctttgctgtt gctggtttag
     3901 ttggaggatt aggagataaa tacgcaagaa atgtggcagc acatgctatg catgacgcta
     3961 tcagtaaata tattccggaa agccatcgtt ttctacatgg agaaaaagta gcgtatggga
     4021 ttttctatca actggcacta gaaggtcgct gggaaaaaat agacgagtta tatcctttgt
     4081 atcgggaatt agaactgccg gtttctctag aacaaatggg attatttccg aaagataaac
     4141 agataataga taaaatggct gaatttattg attcgaaaga gaaagtgcat ttgattccta
     4201 tagaggtaac acagaaatca ctgatacagt caatgatgga actggaaggt tatatcagaa
     4261 agatctgaag gaggaggaca catggaaaca ttaagtgtag tacaaagttt gttgattgct
     4321 ttatgggtag ccgcggttat gtcccgctgg ttaggtggag gagccacgtt gaccttacgt
     4381 ttttctcctt tgatgactgg attagtcgtc gggttgatca tgggggaagt tgcacaagcg
     4441 atgattgtta cagccgcttt gcaaatgatt tatatggggg ttttttctcc aggaggatca
     4501 atgccagctg aaccatctat tgcagcagct atcgcagtac cagtcgcatt attaggggat
     4561 ctgtcgccag aagcagcgat tgccgttgcg gtgccagtcg gattgctcgg aagttacttg
     4621 tatcagtttc gttttttcat caatactttt ttaggtaaat atacagacaa agctgtagaa
     4681 gatttgaata caaaagctat ggcccgatca attattcttt atccaacggt tgcctcattt
     4741 ttattattcg ttccgcttgt tttcattgct ttatatttag gggcgccatt gatcgctgat
     4801 gtaatcaaag ctttagaggg aacagtcgtt atccacattc ttgaagtagt aggtggaggg
     4861 ttagcggcaa tcggtatcgc gacaactgta tacgttatcg gtcgaaaaga ttatctggtc
     4921 tttttcttcc ttgcttattt tatgagtgtt gttttgaaat ctttagatat tacgatggtt
     4981 acttatgcca tttttgggat tattatcgct ttgatctttg tccagtcgca aaaagggaaa
     5041 caagtacagc ctgccacaag caataacaat tcagcatctt ttgatgacga agatgactat
     5101 gatgacggat tttaatttag gaggaatggg aaatggctga aataatggat aatcaaacag
     5161 gtgctcctga agaaatcacg aaaaaagatg taacaaaagc ctatctgaga tggcattttg
     5221 caaacgaaat tcctcactct tttgaacgtt acttggcgcc atcactacta tacggaatga
     5281 tgccaatctt gaaaaaactt tataaagatg aagactcttt aaaagcagca tataaacggc
     5341 agttactgtt cttcaacact caattaagct ggggtggcgg tgtgattact ggcctaatgt
     5401 cttctatgga acagcaaaga gcagaagaag agtatgaaga aaaagagatc ttgatgcagg
     5461 atgacttgat gtataacacg aaagcgggat tgatgggggc actagcagga atcggagatg
     5521 caatcgattc aggaaccgtc caatatattt ttatcgcaat cgcggtacct tgggcacaac
     5581 agggaagtcc tttaggcgca ctttttcctt ttatctgctt tgggttgtat caggttttac
     5641 taggggtatt tttcgcaaga caagctttca ctatgggccg taatgctaca ggcctaaagc
     5701 aaaacactgg tgttcagaca gcgattgaaa tgctatcagt tttagggttg tttatgatgg
     5761 gggtgcttgc gggaaactat gtaaaagtag aatcttcatt gaaatttgcg atatccggac
     5821 gtgagtttgt tatccaggaa attcttgatc aaatcgtgcc agggatatta cctttagctg
     5881 tcgtaatggg tgtgtacttg ttctatacga aaaaaggatt gaaagtcaca caagcattat
     5941 tatggctgac tggaatatta attgtgctag caggaatcgg tattttataa aaagaaggga
     6001 acgtgaataa gatgggtgta gtcaatttag cgcgtgtgga tgagcgtttg atccatgggc
     6061 aagtaatggt aacgttatct caaaaaagtg gagtgaattc catttttgtt gtagacgaag
     6121 ttgtagcaaa agataaattt atgagagatc tttacaaaaa tgcaggaagc cgtacaggac
     6181 aaaaaacaat tgtcattaca ccagagaaag ctaaattcta ttgggatgaa tatcaattta
     6241 aagaatacaa ttgtattttg atcgcaaaaa cagtccaaac gatttacgac ttagtaaaac
     6301 acggaatccc catggaagaa ttgaatattg gagggattgc tcaaaaaaat cctgatacag
     6361 atcttttagt gacgaaatct gtttatttaa ataaatcaga tgctgaaaaa ttgaaagaaa
     6421 tgaatgaaca atatggcgta aagaatattt attttcaagc cactccatct gcacctaaaa
     6481 caggattaaa agatgtattg aacaagtttg atttgtcata aacaaatgct tagaaaaaag
     6541 ataaagaggg cgaaaaaatg aagaagaacg agctgtttcg tgattgggaa tttcgttatc
     6601 gctatattta ccgtaagcgc cgtacaaaaa agagtaaaca gcgttttctt tcagcattag
     6661 tatcagatat ttacagtatg agaacagatg tgacagtcat tgcttacgat acgctagcct
     6721 accgatcaaa aaatatttat gttggagata tcgaaaaagc agagaaagtt atctgtactt
     6781 attacgatac acccgttcat gcattaggaa gttatttcat gtttgattgg aaagaccaaa
     6841 ggaaaaaaac aatctactct atattattgt ccttcatttt gttgttcagt ttaggttggt
     6901 ggggaatgat gatatataac aaaaatcctc atcacgtatt cgatctgcta tccgtataaa
     6961 caggtatcac tgtactagca tttgggagct actttttctt attgggaaaa gcagctcgcg
     7021 gatggcctag cagacaaact tttattcgaa atacttcatc catattaacg atgctagaaa
     7081 tgatccgtac gattgatgat ccgagtgtag cgtatgcgtt tgttgatgaa ggctgttatg
     7141 gagaaaaggg cttagacagc gtgagatcgg gtatgaaaaa agaggctatt cttttttatc
     7201 tagactctgt tggggcagat acaccgctac agttttcggg aaattatttt tcaaataaag
     7261 aacagtggct gaaacaagtt gataagttga aagaaaaaaa cgtcaattat atttttagtg
     7321 caagaaaaaa gcaagcgcag ttcttctatt tgaccaaaac agatttacga gggaaaacat
     7381 ttaattggca aaatgccaat cagattattg ctctttttcg ataagtaaaa agtgcaaaac
     7441 aaggagtgag aagactaatg ttggaaatca tgatcgttac acatggtaag ttgagcgaag
     7501 gactgaaaga tgcggcggaa gtaattgtcg ggacatcgag ccatattgaa acaatgtgct
     7561 tagagtctgg ggaggacatc caaacattcg gagagaaggt caaagaaaaa ttaactatga
     7621 tcaacacagc agaacccatg ctagtatttg ttgatctaat tagcgcaagt ccgtacaatc
     7681 aagcgctctt ggcagtcaat gaactgactg aagaaaagaa agcagccact tatgtcatag
     7741 ggggcgtgaa tctgccaatg ttgttagaag caatcaatca tcagatgctt cacacaccga
     7801 tagaagaagc ggtggaacaa attgtcaaac aaggaaaaga taatttaact gtttggcatg
     7861 cttcagcgga agaaaaaaaa ttagatgagg acgattttta gaaggaaggc tgaaaagatg
     7921 aagtggggat ttagatggta tggtgaaaaa ggggattcga tcccattaaa atatgttcgc
     7981 caaataccgg gaataaatgg gataattgga actttgctga ctaaaatgcc tggagatgtt
     8041 tgggagattt cagaaattga ggagttgaaa gcatctgttg agagccaagg actggaactg
     8101 cttggaattg aaagtgtagc gatccacgat gcaatcaagg cagggacaga tgaacgagat
     8161 tactatattg ataactatat acgaacaatc aaaaacttgt ctcgatgtgg ggttcgattg
     8221 atttgttata gcttcaaacc aatttttgga tgggcgaaaa ctgatttgtt taatgaaaac
     8281 aacgatggaa gctattctct tttatacgat cagaaaatcg tcgatcagat ggagccagga
     8341 gaaatgtatc aattgataca cagccagtca aagggattca aattgccggg ttgggaagaa
     8401 gaacggttga aaaaattcgc tcagctggaa aaactgtatg aaggaatgac cgaagaagaa
     8461 ttatttgaaa atctgactta ttttttagaa aaagtgattc cagtgtgcga aaaagcagat
     8521 gtaaaaatgg ctatccatcc agatgatccg ccatgggaac tttttggttt tcctagagtg
     8581 acgaaaaatc ttggcgactt gaagaaaatt ctaaatgcag tagattctcc atataatgga
     8641 ctaacgctgt gcacaggatc tttaggggca aatccggaaa acgatttagt tgaaatcatc
     8701 catgaggtag gttcgcgcat ccattttgtc cacttcagaa acgtggagtt tttaggagaa
     8761 agaaagttca aagaaacggc acatccctct acagaaggct cccttgatat gtatcatatt
     8821 atgaaagcgt tggtgcaaga agggttcgac ggtcctatac gccctgatca tggtagaacc
     8881 gtgtggggtg aagtggctat gcctggatat ggcctgtatg atcgtgcaat gggactcact
     8941 tacatgcaag gtctatatga ggcgataagt aaggaaaaac cactgggaga gcattatgaa
     9001 taaaatcaag ctcttcatct ttgatatgga tggcctttta ttagaaactg gacgtttagc
     9061 ttatcgtgct tatgtaaaat cagcacaaaa gtatgattat gaaatgcgta aggaagtcta
     9121 ttatttacta actggccaaa cagaaatggc gataagagaa caaatgggca ttttgtacgg
     9181 agaagatgtt ccatatatca aatggcgaga agcaatcaat caatataaag aaaaaatcgt
     9241 gaaagaagat aagagagtat atacgaaaaa aggagcagaa gaaattttat cttttgcaaa
     9301 agaaagagga atccatacaa tcgtggcttc gtctaataca cgggtaaaag tagaaatgta
     9361 tttaaaaatg gaaaatctat atgccttgtt tgatcaaatc atttcagggg atgatgtaaa
     9421 aaaaggaaag ccggaaccag agatcttttt gaaagcttgt tcaaaaatga atattcctcc
     9481 aagtgaagca cttgtatttg aagactcgat tgcagggatc gaagcagcaa ggcgagcggg
     9541 cattttgtct tttctcatca aagatcattt gatagggttg cccgatcata atgggaagca
     9601 taagttgaaa gtagatgtaa gtttatatga atccaataaa gcagactatg aattttatga
     9661 cctgcatcaa gcaaaacgat ttttagaaag taaagggttg tatctctaat aaagaggact
     9721 attttctagt cctctttatt tattgtcctg cacgactgag ggaacagatg aaaaagaagt
     9781 aattttttat tttgaagtat ctaccttatt tgtagtgaac aatttagaac aaacacaaaa
     9841 cgcatctact gtt
//
LOCUS       DADQCX010000095         9853 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.096, whole genome shotgun sequence.
ACCESSION   DADQCX010000095 DADQCX010000000
VERSION     DADQCX010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.096"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(80..2200)
                     /locus_tag="J8R83_002297"
     CDS             complement(80..2200)
                     /locus_tag="J8R83_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9575413.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2430..3608
                     /locus_tag="J8R83_002298"
     CDS             2430..3608
                     /locus_tag="J8R83_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAZ9575414.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3624..4382
                     /gene="aroD"
                     /locus_tag="J8R83_002299"
     CDS             3624..4382
                     /gene="aroD"
                     /locus_tag="J8R83_002299"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAZ9575415.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4405..4890
                     /gene="ybaK"
                     /locus_tag="J8R83_002300"
     CDS             4405..4890
                     /gene="ybaK"
                     /locus_tag="J8R83_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAZ9575416.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4961..6214)
                     /locus_tag="J8R83_002301"
     CDS             complement(4961..6214)
                     /locus_tag="J8R83_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9575417.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6330..7679
                     /gene="gdhA"
                     /locus_tag="J8R83_002302"
     CDS             6330..7679
                     /gene="gdhA"
                     /locus_tag="J8R83_002302"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAZ9575418.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7791..9137
                     /locus_tag="J8R83_002303"
     CDS             7791..9137
                     /locus_tag="J8R83_002303"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAZ9575419.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9445..9831)
                     /locus_tag="J8R83_002304"
     CDS             complement(9445..9831)
                     /locus_tag="J8R83_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9575420.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3142 a         1792 c         2013 g         2906 t
ORIGIN      
        1 attattctaa gatttctctt taccaacatc atttgacaaa gagcctaatt ttgtcgctgc
       61 tccttttaaa tttattttat cattcggaag aacttgtggt cgttccgtga agttcttggt
      121 acgtttgcgt tttataaaga tcaacagttg attgtccctt gtgttcacta aagacactag
      181 ttgacttgtc accaagagat ttttcagctt cttttaattt ctctaagcca ttcttgtagt
      241 cataatcact ggtatcaatt gggtctaatc cactattcgt atagaaccga agaagatcac
      301 cattattgat ttggtcagaa acagctaact gtttatcaac tttttctttc agtgaatcaa
      361 tttcattctg tacttcctca gtaggttcag taatagcttc accagtttcg ttactataga
      421 tcgtaccacc gtagtaagta tattttggtg taacaaaatc accatcacgg aaagaaacaa
      481 gctgttcatg atctttcgag aatagatctt gtcctaactg aatataattt tttgtatcta
      541 cacctagtaa gtgaagtaat gtaggcaagg catcaacttg tccgccgtaa gtgtgattga
      601 ttccgccctg tgtttgtcca gggatatgga tcatataagg gacacgctgc atttgtgcat
      661 tgtcgtagtt tgtccaagta gaacttgttt ttccaactaa ttcagctaga tttttatttc
      721 ttgaattcga gacaccgtaa tggtcaccgt aaaggacgat gactgaatta tcatacaagc
      781 cgctttcttt caaataattg aagaattctt gtacggcggt atctaaataa ttggctgtcg
      841 caaagtaacc gttgatcgtt tcatcatttg tattggctaa cgggaatcct gcttcgtcat
      901 tggtgaattt tgaataagga taatggttag atacagcaat gaattttgaa taaaatggtt
      961 gttgcagacg ttccaagtat tgtacggatt gttggaaaaa tggtttatca tgcaacccgt
     1021 attggaacga attgtcatca ttaacatcat aataagaaga atcaaagaaa taatcatatc
     1081 ctaaattctt gtatgtctcg tttcgattcc agaatgtacc agcgttccca tggaataccg
     1141 cactagtgta accttgtgtt tgacttaaaa tatcaggtgc agcttggaaa gtattttttc
     1201 cgcctaattg tgtgaacaag gagccttgat tcaagccaaa caatgaattt tccatcagcg
     1261 tttccgcatc gcttgttttt cctgctttta cttgatggaa aaagttgtca aaactgaacg
     1321 tgctgttgct gtggtaaaga ctattgatga aaggtgtaac ttcaagctgg agaccattct
     1381 catctgtcaa tttataatcg atcaggaatt gctggaagct ttctaaatgg atataaatca
     1441 cattttttcc tttagcgagc ccgaacaaat catcatttgg tgctgcataa tgttctttta
     1501 cataattttc tacttctttc atatcattgg gacttgcttc tgcccgcact tggtttgtct
     1561 ggtaagtttg aacaccgtca taaaccatga aagcattcaa gccaagatat ttgaccaaat
     1621 aatcacgaga gaatgttcga gtcagcaatt ctggacgatc agcttccgcc ataaaaagat
     1681 ttcctgagaa aatcataact gctaatgtag agatcgcaaa agccattctt gctcggatcg
     1741 ggcgagggtc caacttgatt ttttttgcaa tcagcagaac agtcaagata ataaaatcga
     1801 tccaatagat cacatcatat gggcgaaaca gtcgaatggc actttctccc agaccactcg
     1861 ctactttccc agcacctaaa atcgtgttga tcgtaatgaa gtccgtgaat tctcgataat
     1921 aagtgacatt cgaaaaaaca agcaatgtca aaagaaaata aatgaccatc atcgtgatat
     1981 aagcaactct agggcgtctg atataaagag caattccaag taataacaat gtagttgcaa
     2041 tagggttgat aaacaagata aagtattgaa tgccactttc gattccgaga tggaaatcaa
     2101 ctaaataggc aaaaatcgtt ttcaaccaaa gtaaaacaac tagtaaagaa aaaaatccga
     2161 gcctcttatt caaaaaggca ggtgttttta tacatttcaa gataatcttc ctttctgcac
     2221 ttcttaatca cagaagtgtc atgaaaccat gttacacagc tcacttattc tcatttattt
     2281 tactagtatg acaatatagt gtcaattgaa accagaagtt tatgctgttt cattaaggtt
     2341 ttctttaagc ttcatgaaaa aatgagcagt aagacaagtc ctatgttttt tgttatactt
     2401 gggaagagaa agctaaagca ggtgaaggaa tgaaagtaaa agtaaaaaaa agagcaagca
     2461 atcgattgaa aaaaggatat ccactgatcc aaaaagaaga ccttgctcat ccccaaaaag
     2521 aaaccacgca atgggtggaa ttagttgatt cgcaaaacca atttatcgca aaaggatatc
     2581 taggaaagca gaataaggga atcggttggg tattgagcca gcagaacatc ccatttgatc
     2641 aatctttttt tgaagaattt tttgtgaagt caaaagaaaa aagaactttc tttttttcag
     2701 atgattctac taccgctttt cgtatattca atggagaagg agacgggatc ggcggtctga
     2761 ttgttgatta ttatgcaggt tatgctgttt tttcttggta taacgaaacg ttatatgcac
     2821 atcgtgaatt attgattcaa gcttttcgtg aaatctaccc ggaaatcgta ggaggctatg
     2881 agaaaattcg atttgaatca gtaaatctgc ctgagagcca gttcatttac ggaaaagagg
     2941 caccggaacc cttgatcgta aaagaaaacg gagtaaaatt tgccgtttat ttaaatgaag
     3001 gattaatgac tgggatcttt ttagaccaaa aagaagtacg gggatcatta gcagaaggtt
     3061 tcgcttctgg gaaaacagtt ttgaacatgt ttagttatac cggcgccttt tctgttgctg
     3121 ccgcaatggg aggggcaatc gaaacaacaa gtgtcgatct agcaaaacgc agtttaaaaa
     3181 aaacacagga acagtttgaa gtgaatggtt tggatgtcga tcagcaaaaa atcattgtta
     3241 tggacgtatt cgagtatttc aaatacgcca aaagaaaaca atttttatat gacatgattg
     3301 tattggatcc accaagtttt gccagaaata agaaaaaagt ctttcgcgta gcaaaagatt
     3361 atggggaact ggtcaaggat agtctggata ttttagcaga agacgggata cttattgcgt
     3421 ctacaaatgc tgcgaatgtc tcgatagaac aattccaaac aatgattgaa gaggaattcc
     3481 atgccaaaaa tgtttctttt gaacaacttg ctttatatcg tctgccaaaa gatttccaga
     3541 cgacggatac ctttttagaa ggcaattatc tgaaagtgtt tgtttatcaa attaaaaata
     3601 accattagaa ggagcgatgc agaatggttt gggtaaaggg attgaatata ggaagcggta
     3661 gaccaaagat ttgtgcgcct cttatcgggg ccgtccgaga ggaagtatta cgtgaagcag
     3721 ttcttgcacg tgaagcaggg gccgatttag tcgaatggcg agtcgatcat tatcgtgaag
     3781 ttttttcttt tgatgaagta gcagaaacat tggttcttat ccatgagatg cttgatggac
     3841 tgccgttatt atttacgttt cgtaccttag ctgaaggcgg agaacaagac atatcgatcc
     3901 gtcagtatcg cgacctttat gaacatgtga tacacacagg attagtagat atggtcgata
     3961 tcgagttgtt caaagtagaa agtctaggaa aaagactgat agaggaaatc aagtctttaa
     4021 acattccttt aattatcagt agtcatgatt ttaaagaaac accagcagac cctgtcttgc
     4081 tttaccgatt gaatgttatg gaacattttg gagccgatat cggaaaactg gcagtaactc
     4141 ccaataatga acgagatgtt ttgcggttga tggagttgac tagacgggca aatgcttttg
     4201 tctccatgcc tattattacg atgtccatgg gaaatcttgg taaaatttct cgtctggctg
     4261 gcggaacgac gggttccgtt atgacatttg gttccttaag cagcgattct acttctgctc
     4321 caggacaatt accggtcaaa gcattgaagc aaattattca attattaaat gaaccgttgt
     4381 agaacaagtt tgaggtgata ttttttggca aagaaaaaaa tagtaaaaac gaatgcaatc
     4441 cgtatggtcg aacaaaaaaa gattccctat acagagcacg aatatgagtg ggacgaaagc
     4501 cacctaagtg cgtcatcggt cgctgaacag cttccagaaa gccaatctca tatatttaaa
     4561 acactggttg ctgtgggcaa tgtgacgggg cctcttgttg ctgtgatacc gggagaagcc
     4621 gaattgaatc taaaaaaatt agcaaaagtt tcagggaata aaaaagtaga aatgctccat
     4681 ttaaaagatt tggaagcaac gaccggatac atacgtggtg gctgctcgcc tataggtatg
     4741 aaaaaactat ttcctactta tttagatcaa attgcagaaa gctatgaaca aatcattgtc
     4801 tcggctggca gaagagggct acagatggag ttagcacctc aagatatctg tgcattaacg
     4861 agcggacaat ttgcagatat aaaacaataa atcatacgta taaaagaaag aaggaggccg
     4921 ggatgttgtt tgtccagtct ccttctttct tttttataca ttatgctctt tgcccggcat
     4981 tcattcctgc tacatgccct gtagcgaaag ccgctgtgat attaaagccg ccagtataac
     5041 cattgacatc cagtaattct cccgcaaaat acagaccatc aatgatttta ctctccaatg
     5101 ttttaggata aatttccttt agagaaaccc ctccgccagt tacaaatgat ttctcaatag
     5161 gaaaagtttt gttgattgat agcttaaact ctttgcatag ttgaacaaaa tcttgaattt
     5221 gtttttgaga ggcttgttgt cctgtcagat gatccatttc aagccgctca agaaagaaaa
     5281 ctaacaatcg ctcaggcaat ataccatgcc aagcattgac caagttcttt ttggttgctt
     5341 tacttttttc tgtcaatata tgaataagct cttgtttggt ttgtgtaggg aaacaatcca
     5401 gagaaagtgt cactggttct cccgttttct ctaattcttt attgacaaaa cttgaacaac
     5461 gcagtgcagc cggaccagaa ataccgaaat gggtgaaaag taaatccatc gtatgttcag
     5521 tcaatacacg acctttttta tttaaaacgc gtaaagtgat gtcttgtaaa gaaagccctt
     5581 gaagtgtttt ctcctgaata tacggttcat ccgatatcaa gggggactct gtcgcataaa
     5641 gaggcgtcac cgtgtgaccc actcgcttca cgatcttgta cccatctcca gtagaaccag
     5701 tagatggata agtccgtcca ccagttgtta agataatggc aggagcatgg aactcttcga
     5761 attccgtgcg tataccgtaa attttatgtt ctttgtggat caatttctct actcgagtag
     5821 agaatagaag cgtcacatct agttctttca gacgattgag caatgcttcg ataatcgttt
     5881 ttgatttatt tgttacagga aacatccgtc catgatcctc ttcttttaaa tgtacgcctt
     5941 gtgattcaaa gaagttcatg atatcgaaat tattccattg cgcaaacgta ctatataaaa
     6001 actttccatt tccaggaata tgtgcaatca aatcatcaac aggacgattg ttcgtaacat
     6061 tgcaccgacc accacctgtc atcagtagtt tttttcctgc ttttttgttt ttttcgatca
     6121 agagtacgcg tgcgccttgt tcagctgcac tgatcgctgc catcatcccg cttgttccag
     6181 cgccgactac gatcacatca tacagttttt ccattccctc acctcaagga aagtgtagca
     6241 tatctgaaga aagaaaacag aaaaaatgtt ttgagccaaa agagaaaatg agctaaaatg
     6301 agggaagata agcaaaggag cgtggaacga tgacaaacgc aacagaatat gttcaagcaa
     6361 ttcaagaaaa gctacatcaa aaggatcaag ggcaagaaga atttttacaa gcaatcgatg
     6421 aattcatgcc cacggttatg tcttttttgg acactcatcc cgaatatatc gaaaagaata
     6481 tcttagaact tttaacggaa ccagaaagag ttattcaatt tcgagtgcct tggcaagatg
     6541 atgaaggaaa ctggcgagta aatagagggt accgtatcca atacaactca gctatcggcc
     6601 cttataaagg tggattgcgc ttccatccta gtgtcaatct aagtatcttg aaatttttgg
     6661 cttttgaaca gattttcaag aatagtttaa ccggtctgcc aatcggtgga ggaaaaggcg
     6721 gaagtgactt cgatcctaaa ggaaaatctg ataatgagat catgcgtttt tgtcaaagtt
     6781 tcatgctgga attgtcaaaa catatcggcc catcgattga tgttcctgcg ggagatatcg
     6841 gtgtaggagc tagagaaatc ggctatttgt tcggcgaata taaacgattg aaaaaatatg
     6901 atactggtgt gttgacaggt aaacctttgg atttttgggg aagtaagata cgtacggaag
     6961 ctactggtta tggattagtg tattatgtca aacatctatt gaacgaagaa aaagattcat
     7021 ttaatcaaaa aacagttttt gtttccggaa gcgggaatgt agccatttat gcaatcgaaa
     7081 aagtgcaaga gctaggcggg aaagttgtta catgttcaga ttctagcggg tacatctatg
     7141 atccagaagg aatagatgtg aaactattga aagaagtcaa agaaatcaat agacaacgtt
     7201 tgacggaata cgcaaaccaa cgtccttctg ctatttatca tgctggagaa tctgtttgga
     7261 cattgaaaga aaaagcggat atcgctttgc catgtgctac tcaaaatgaa atagacgaaa
     7321 gcttggccga aatcttagta gaaaatggga tcaaaatcgt agcagaaggc gctaatatgc
     7381 catgtacagt aaaagctgtt tctgttcttc atgaagcagg cgtgtggtat tgtccaggaa
     7441 aagctgctaa tgctggagga gtagcagtat ctgctttaga aatgagtcag aacgcccagc
     7501 gattgacttg ggaaagagag caagtggatg agcagctgga tcaaatcatg gaaacgattt
     7561 accatacgtg tcgccaaaca gcagccgagt acggcgacga aaaaaatctg cttcttggag
     7621 caaatgttgc tggatttgaa aaagttgcca aagcaatggc agcagaaggt ttagtttgaa
     7681 aaatgaaact ttcttggaaa tattgtcagc attttgttta tttgcttgaa aaataataaa
     7741 aaaaaacgta aagtattacc tgtagagtaa acctataagg aggagaacaa atggcacaca
     7801 ttcattttga ctattcaaaa gtagcaccgt ttgtcaacga acaagagtta gggtacatgc
     7861 aaagccaagt aacagcagcc cacaacgaat tacgggaagg tactggcgca ggaagcgact
     7921 tccgcggctg gatcgattta ccaacgaact atgacaaaga agaatttgca cgtatcaaag
     7981 aagcagctaa aaaaatccaa tctgattctg aagtattagt tgttatcggt atcggtggtt
     8041 cttatttagg cgctcgtgca gcgatcgact tcttgaatca cacattcttc aatttattag
     8101 atagcaacac aagaaaagca ccacaaatct tctttgccgg aaattcaatc agctcaacat
     8161 atattgctga cttgatcgaa gtaatcggtg atcgcgactt ttcagtaaac gttatttcaa
     8221 aatctggaac aactactgaa ccagcgattg cgttccgtgt attcaaagag cttcttgtta
     8281 agaaatatgg acaagaagaa gcaaacaaac gtatctacgc tacaacagat aaagcaaaag
     8341 gtgcagttaa agtagaagca gatgcagaag gttgggaaac tttcgtgatt cctgatgaca
     8401 tcggcggacg tttctctgta ttaactgctg ttggtttgtt accaatcgct gttagtggtg
     8461 cagatatcga tgcattgatg caaggtgccg ctgatgcaag caaagcatac tcaagcgaca
     8521 aactagaaga aaacgaagct taccaatacg cagcaatgcg caacattctt taccgtaaag
     8581 gcaaagtaac tgagttgttg atcaactatg aaccaggaat gcaatacttc tcagaatggt
     8641 ggaaacaatt gtatggtgaa tctgaaggaa aagaccaaaa aggcatctat ccttcaagcg
     8701 caaacttctc aactgatttg cactctttag gacaattcat ccaagaagga cgtcgcaata
     8761 tttttgaaac agttgtgaag gttgaaaaac ctcgtaaatc aatcacaatt cctgaacaag
     8821 cagaagattt agacggtcta ggctacttgc aaggaaaaga agtggacttc gtaaatacaa
     8881 aagcatttga aggaacattg cttgctcata cagacggtga cgtgcctaac ttgctagtca
     8941 aaattccaga aatggatgct tatacattgg gttatacaat gtacttcttt gaaattgctg
     9001 taggtatttc aggttacttg aatggaatca acccattcga ccaaccaggt gtagaagctt
     9061 acaagaaaaa catgttcgca cttctaggca aaccgggctt tgaagatctt gctaaagaat
     9121 tgaacgaacg cctgtaagat aagggttttt cgctagattt aaataatcag tgatagaaac
     9181 atgttcgctt taaaatgaaa actggtaccc atttaggtac tcaaacatac tgcatcgttt
     9241 attcagaata aggggctgtg acaagacgtt tgtcacagtc ccttgtttgt atagaaatcg
     9301 attgattgcc ttgctcttta gtttgtttta ggactttaag aacagtgagg ctgacttcga
     9361 aggttaattc tgtttttttg ttttctagaa tcagtgagca aaaaagcact cacttcgagt
     9421 gcttttttgc gatatattct tagcttaaga taggcctaat ttttctttta cagatgaggg
     9481 taccttatcg ctggtaatta cttttttctc tatgatccgc ttttcgcttg ctttcaactg
     9541 caagatcgtt ccttcggtgt aagcagaacc attggcagag tcaccagaag taatgacatc
     9601 gaaatctaac tgtctttttt caccgttttc agcataagca tctacgttgt atttaaaacc
     9661 tcttccaatt acttccccat tatctgcttt gatatcagtt tctgcaggca ttggagcttt
     9721 gactaccgca taataatctt tacctacata agtagactga tagtagtccc aacctttcca
     9781 tcctataaaa gcaatcaata tgataacgat caaccctaaa atttttttca tgaaagatct
     9841 ccttttttat ttt
//
LOCUS       DADQCX010000096         9271 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.098, whole genome shotgun sequence.
ACCESSION   DADQCX010000096 DADQCX010000000
VERSION     DADQCX010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.098"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1350)
                     /locus_tag="J8R83_002305"
     CDS             complement(<1..1350)
                     /locus_tag="J8R83_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9575421.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     "
     gene            complement(1352..2020)
                     /locus_tag="J8R83_002306"
     CDS             complement(1352..2020)
                     /locus_tag="J8R83_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAZ9575422.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(2150..2734)
                     /locus_tag="J8R83_002307"
     CDS             complement(2150..2734)
                     /locus_tag="J8R83_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9575423.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(3065..3298)
                     /locus_tag="J8R83_002308"
     CDS             complement(3065..3298)
                     /locus_tag="J8R83_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAZ9575424.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(3313..4263)
                     /locus_tag="J8R83_002309"
     CDS             complement(3313..4263)
                     /locus_tag="J8R83_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAZ9575425.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(4260..5102)
                     /locus_tag="J8R83_002310"
     CDS             complement(4260..5102)
                     /locus_tag="J8R83_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAZ9575426.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(5104..5823)
                     /locus_tag="J8R83_002311"
     CDS             complement(5104..5823)
                     /locus_tag="J8R83_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575427.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            6515..6673
                     /locus_tag="J8R83_002312"
     CDS             6515..6673
                     /locus_tag="J8R83_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575428.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            6745..7971
                     /locus_tag="J8R83_002313"
     CDS             6745..7971
                     /locus_tag="J8R83_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9575429.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(8059..8451)
                     /gene="rpsI"
                     /locus_tag="J8R83_002314"
     CDS             complement(8059..8451)
                     /gene="rpsI"
                     /locus_tag="J8R83_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAZ9575430.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(8467..8910)
                     /gene="rplM"
                     /locus_tag="J8R83_002315"
     CDS             complement(8467..8910)
                     /gene="rplM"
                     /locus_tag="J8R83_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAZ9575431.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
BASE COUNT         3157 a         1620 c         1302 g         3192 t
ORIGIN      
        1 tccaccattt tttaaataaa taattctatt gcatgtttta taaagaaatt ccggatcatg
       61 agtagctata actactgcac ccttttcttt taagtcttta ataaggtcag caatcctttc
      121 catattaata taatccaacc cacttgtagg ttcatcaaat agaaataaat tagtttttga
      181 caatgaagct atagaaacca ataatctttg tttttctcca ccggataaat caaacggtaa
      241 ttgatctttc attttataaa gttccatttt ttttaaaatt ttttcttgct gatctttact
      301 aactatttca ttccccaggg ctaactcgct cctcactgat tctgtgaaaa attggtaatc
      361 catttcttgc attactaaaa acggcgatga caaatttttt ttattttcga ttatctttcc
      421 tttggtaggg cgaataatct tcatgagtat tcttagtaag gttgttttcc ccacaccgtt
      481 tttccctacc aaaccaataa catctccaac tttgacatca aaatttatgt cttttagaat
      541 attttcataa gtaatttctt caacttttaa tacatctgca cttacctttt cgatataggg
      601 aacttcaatc gaactattaa aaatgtcaaa tttccttaat gcgttattgt tttcagtttt
      661 taacaactga atagttgtag tttttacagt tctattttta acaaatagaa cttgatcaat
      721 taattctttc aaatagtaaa aacgatgttc agctataaca atagtaaatc ctttattttt
      781 taaatcacaa agtaagtcag caagtttctt agtcgctttg aagtccaaat ttgaagacgg
      841 ttcatccaat ataattaatt tagagtttag cgataaacta catccaatag aaattttctg
      901 ccgttcacca cttgatagcg aaaaaatgtt tttatctaat atatttgaaa gatctaataa
      961 ttcagctaat tcattgattc ttttatccat atgctctttt gtaaatccaa agttttccat
     1021 cgaaaatact aactcactcg ttgtatttgt tgtaaagaat tgtcctctag gatcttgact
     1081 tacgtagcca atattttttg atatactttc ttgtgttaag gattgtagcg agttattttc
     1141 aaataaaatt tccccaacca attttccgtc ataaagtctt ggaataagtc cattcattaa
     1201 ctttaatagt gtggatttcc cactcccaga agaaccagta atcaatgtaa gactgccttt
     1261 ttttattgaa aaattaaggt caacaagcgc ttgttcctta acatccttat atgaaaaaga
     1321 aacattgtta aattcaaaca attctttcac ctcaaatcaa aatacttaag aaaaaaatag
     1381 taacggaaaa caggatgata tagtctaata agctcatgtt tgttttatag taagaacttc
     1441 ttttcacagg agattctatc ccctttgtta ttgcattagc ggtcatttct tcagcaatca
     1501 tagttgcacg tataagaacg ggaactaaca gaaattccaa atattgcaga ggctgaaaaa
     1561 aagacaagcg aatgtttctc atttttaaag attctttaat cattcttatt tcagaacgat
     1621 aagtcggaaa gaatctgatc actactgtaa tacttaacat tatttttttc ggtaaatgta
     1681 ttttttctaa agaggataat aattcattgc tagtatagac actaaccaac aaccatgaga
     1741 tcattacgac cggcaacatt cgaaatacaa tatataagga tgtcgcaaaa aatatagtaa
     1801 aaaactctat cttgatagca tcaataattt tcattactaa aaacagaact gaataaatca
     1861 agatgaaata aatacatgtc tttattttac gaaacatcaa tactaaaact gtagcaataa
     1921 tgaaacaccc cacttgaaat atatttccct ttcctaaaaa aataatgacc ggaaaaaaaa
     1981 tatttaaagt aatcaaggtt aacggattga tttttgacac tctttcacct ccaaaaaata
     2041 agatcgcact gttatcttaa gctgataaaa atgcaccgtt attcagataa cagtgcgatc
     2101 ttatcaaaaa gcataactga gaacaattct caatgcaagc tttttttaat taactcagta
     2161 attcaatcca cccaggaaca gaaaattgat acaatcttct ggttaatagc atagtctttt
     2221 cttttgaata gctatgcttc aatatatcat agaatgtagc gtagaatgag taaatgtaga
     2281 agtggatttc ttcttcatta aagactaaat tttgattgat cattccgata gtctttaact
     2341 tatctagaca acagactgtc tttttcgtca caaatgatgt aattttttca acaatatctt
     2401 gatatttggt tccagctgat tggaataaaa tcaaatcgaa tatacgttta ttctcaaaaa
     2461 tataattaat aaatggatct aattcattga agttctctct ccaacttttc tctatatcta
     2521 tattttctaa gtttaagagg tatttggtaa actcttcatt atacatatta ataagcgcat
     2581 taatatgcgg ctgaataatt tcttcaaata acgcttcctt agaagtaaaa tgtttataaa
     2641 aagcacccgt agttacgcct gcggtcaggc acagttgcct tatcttagtt tgctgaaatc
     2701 cttctttttc aaaatggctt agtccacttt ctattaactt ttggtgagtt ataatataat
     2761 ctctggtttc tatgggtact tcctcctaat aagatgaatt aactttatta tcttacacag
     2821 gacttgaagt ttcaatcgtt aacgtttatt actgaactca ttccttagag ctaaactaat
     2881 gagaaagagc agaataactg atacaaaaag caatcctaca agaattaata gactcatcta
     2941 aatcattcac cttttctaaa ataatccgag aaagatttaa aaaaattata tccagctatt
     3001 aggataagtc ctatcataat cactccaata gccattttct tatcctccct aaaaataaag
     3061 tcttttactt aaaacctttt ttgtaatcgt caataaattt tttcccttta tcagttaatt
     3121 gaaatcctat atctaaatag tcctcatatc taagtttagc cagcatctca cttacagatg
     3181 ctggactaac acttagaact tttgctaaat cattattttt taatttcttt tttctttttg
     3241 ataattcctg aattgctagt aaataaatta gtatagtagt cgttttaatt tgtaccatac
     3301 ctaccctcca aattatttcg aaaggccttc agcaatttta tccaggttcc atttcatcat
     3361 cgcatagtaa ctatcaccat cttgtccttt ttctgcaatt gaatcagtaa aaatcgttga
     3421 atagatagga atattggtat cttttgatac tgttttcatt ggtctatcat ccacactgct
     3481 ttctacgaat aaggagggaa cttttgttgt gcgtaatttt tcaactaagt gttttatttg
     3541 atctggtgtt ccttcttctt cagtgttgat ttcccaaatg taagcagaag gcacattata
     3601 cgctttcgag aaatatttaa agcatccttc acttgtaaca atcatttttt tatcattcgg
     3661 aattgaagca aatttagatt tagcttcttt gtctagagaa tccaattttt caatatactt
     3721 atctagattt tctttataga attttttatt atcaggatct ttttccgcta actgtttttc
     3781 aatattttta gcgtaaataa taccgttttc taaatttaac caagcatgag gatcttcctt
     3841 ccctttctca ctctgaccct ctaagtaaat aacatctatg ccatcacttg ctgcaaaata
     3901 gtctttgttt tcctctttgt tcgcattttt aactaatttt gtaaaccaag catttcctcc
     3961 agtttccaag ttaacaccgt tataaaaaat caaatctgct tttgaagttt tttgaacatc
     4021 ttcaggcaaa ggttcatatt cgtggggatc tttcccaata ggtacgatac tgtgtaaatc
     4081 aattttatct tttgctatat tttcggtaat atctgctaaa atcgaattag taactactac
     4141 ttttaatttt tcgttcgaag ccactttatc tttgtcttta ctatttattg aacatgcccc
     4201 gaatataaaa agagcaatca aaatccccag acttcccagt actgctttcc attttctcat
     4261 cataacgatc tctccttctt tcttaaaaat ttttgttttg gtgagattag aaaactaatt
     4321 acaaataaga atgccgctgt taaaacaata cttgatcctg ctgctatgtt aaaactataa
     4381 ccaataaaca atccaagcaa tgatgaactt gctccgactg ttgcagaaat aaatatcata
     4441 gttttcaagc tatttgcata taaatatgct gtagctgctg gtgtaattaa cattgcaaca
     4501 attaatatag ttcccacact ttgcatagct gttactgcta ctaaagttaa tagaaccatc
     4561 aatagataat gataaaaact gacattcatc cctattgctt ttgccattaa tggatcaaaa
     4621 gaagtgatta ataattcttt aaaaaataga actactataa ccaacactaa aaccgaaacg
     4681 ccaattgtaa tccacttatc aatatcttgt acagctaaaa tatttccaaa taaaatatga
     4741 aataaatccg ttgagctatt tgcaactcct ataaggataa ctcctagtgc taaaaaagaa
     4801 ctgaaagtaa taccaattgc tgtatctcct tttattacac tattgctttt tataaaagta
     4861 ataatgatag aagctaatag accaaataca atcgcaccaa taaaaaaatt aatacctaaa
     4921 atataagaaa ttgctactcc tggcaaaaca gcatgagaaa tagcatcacc cataagagac
     4981 attcctctta aaataataaa acaacctact gttccagaaa caatccctat aactacagat
     5041 gtaattagag cattctgtaa aaagtgaaag tcatacagac cattaataaa attttgaagc
     5101 atattattcc ccctctccaa taaatatagt atctccatag gcttttttta aattttcttc
     5161 attaaataca gattctacac ttccgtgagc aattagattt cgattcaaaa gaataatatt
     5221 atcaaaatac ttctttacct tgcttaaatc atgatgcaca attagcactg tttttccctg
     5281 atgtttcaat ttttttaacg tatccataat tattcgttca ctaactaagt ctatccctac
     5341 aaatggttca tctaaaaata tgaaatccgc attttgagca agacatcttg ctaaaagtac
     5401 acgttgaaat tgtcctccag ataattctcc tatttgatga ttagaatatt ttcccatatc
     5461 gaccttttcc aaagcctttg aaactctttg ccattctgca tttttaattc tttgaaaaac
     5521 tttcattccg gcatatgttc ccatagatac acattctttt acttttattg gaaaagtaaa
     5581 atcaatatca gctttttgct ctacatatgc aatcttcacc agttttttat tgatatcttc
     5641 attattaatg gagacctctc cctgatgagg gataatattt aacattgctt taagcaatgt
     5701 ggattttcca gcaccatttg gaccaataat acctgttaaa gcaccttctt gtatttttaa
     5761 agaaatctcg ttcaatgcta aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa
     5821 cataactttc tccttctaaa tgataatgat tatcacgatc atatggtata caaaaattat
     5881 attttagtca accctaaatt ttatagttta gatttttttc tgttgctgaa gattagaatg
     5941 acaaaactat ttgaaactac gcgtatagta agtagctttc aaaatatata aaaaaggagc
     6001 gttctcaaat gagaacatgc tcctaaaact actttattgg cgtatggaaa aattatactt
     6061 gaagtggata gcgggttgaa taagttgata agcatcaaaa catttataaa aattattcaa
     6121 gactatgtct gttccatata caaatatgaa aatcagtaaa ctccatttaa cttttttcgt
     6181 agtgtgtctt tttatacatg tttatcgtta ttaatagtga ataggaaaaa aactattttt
     6241 gatcattgac aattaaatac aatttttgaa taacgatccc tgctattcga gctagaaact
     6301 caagtacgcc atgacctgat tagcgacaaa tacttagaga tttctttttg ttctgggaaa
     6361 acaaaatgcc atgacaatag cagcaaataa tgatacttcc gtaaggctcg ccgtaaactg
     6421 gggagaggtg aaattcctat gtgcttaccc aaagcaattc aaaaatttca taactactat
     6481 tttaggagat gattttatag aatccagagt ctacctgaat aaaaaacaaa cctgtgcatt
     6541 tctaggaatc gataataata ctctagataa gtggattcgt atatataatt tcccagtaat
     6601 aagagttggt ggtgtagttc gctttgacgt agaagatatt aaagacttta tgaatacatt
     6661 taaaataact tgaaattttc ttctcgccgc atatactaaa attagtgaaa tatactgcct
     6721 tacttttttt aaggagtgag gattttgcct acaaagcttt caaatgggaa atataaaact
     6781 aatctgagat atccaaaaag gtttaaagaa ataacaggaa ttgcatcaga aaagtatcaa
     6841 aaaacatttc caaataggca attggcgatt aaagccgaaa atgatatgaa gaagaaaata
     6901 gaaaaagttt tgagagagga gaatgcaaac tcattagaat taaaaggaaa aataacgttt
     6961 aaaaaatttt acgaatctaa atggcttcct agatatgaat taggtcaaac aattagatca
     7021 aacaggcctc ctagtgatat aaccattagt aatacaaaag atatatttcg gttgcatatt
     7081 ttacctatgt ttggtgaata cgcaatgaat tatctaaata tcaatactga gataatatca
     7141 gatgaattaa ccaaaaaatc gaaagaatat gcaaatataa aaatcataaa aggatatgtt
     7201 cgttccatgt tcgatattgc agaaatacta aattatatcg aatttaatcg aactactaaa
     7261 attattcaaa gtatcactgc acctaaaaaa aatgctttag aagaaaaaag aatacaagaa
     7321 ggtaagcaag cactatcatc aaaagaactt actaattgga tagaagcagt aaatgatgat
     7381 tttaataatc atttacttac ttttcatgat tacacacttt ttatgattac cctgtatctt
     7441 ggtgatagaa aaagtgagac ttacgctttg caatggaaat atattgattt tgaaaaacaa
     7501 acggtccgtc ttaaacatac tttagataaa tatcaaagaa aaaagtttac aaaaggtcga
     7561 aaagataccg tcattcaagt accagaagtt gtaatgacat tgctaagtga atggaaatcg
     7621 gtacaagctg atcaattgtt gaaattaaaa attaagcaaa cgttagatca gtatctcttt
     7681 acttatacta aaccatctgg agaagtaaat tgtcctgttc atgccgatta cctaaactat
     7741 cgaatcaatt caattaaaag aaggcatcct gacttagttc atttatctcc acacaaactc
     7801 cgtcatactt atgcaactat agctagacaa ggtggagcag atatgaatca aatttcaaat
     7861 gctttaacac actcagatat ttctacaaca aagatatatg tgaacacacc agatatagtt
     7921 gataaggctg tttttgaagc ttttcagaga ggattgaata agtgtgattg atatgtgttc
     7981 ttaaatgtgt tcttaaaaac aaaagaagca ctttccaaat aattgaaaag tgccagaaac
     8041 gttgatatat aaaggatatt aacgttttga gaattgtgaa gctttacgtg ctttcttaag
     8101 acctggtttt ttacgttcga ccatacgtgc gtcacgagta agtaagccag cacgtttaag
     8161 agctaaacgg aagtcaggat caacttctag caatgcacga gcgataccat gacggatagc
     8221 tcctgattgt ccagcgtatc ctccgccgtt tacgttaaca aatacgtcat atgcgccttt
     8281 tgtttcagta acagcgaaag gttgattgat tacttcacgc aagtcagcat gtggaatgta
     8341 ttcttcaaca tcttttttat ttacagtaat tttgccagtt cctggtacta gacgtacgcg
     8401 agcaactgcg tttttacgac ggcctgtgcc gatatattga acttgtgcca atgaaattcc
     8461 ctcctattag attaagtttg tgatgtctaa aacttctggt tgttgtgctg catgtggatg
     8521 ttctgctcca ccgtatacgt tcaattttgt aaattgtttg cggcctaaag tgtttttagg
     8581 aagcatacct tttacagaag tttcgatcaa acgacgagaa tttttagcac gcaattcgcc
     8641 agcagtgatt gatttcaatc ctcctgggta gttgctgtga cggtaataaa ttttgtcagt
     8701 cgctttttta cctgttaatt tcactttgtc tgcattgatg acgatgacga aatcgccagt
     8761 atccaaatga ggtgtgaaag ttggtttatt tttaccacgt agtacagatg caacaactgt
     8821 tgaaagacgt cccaatggaa catcagttgc gtctactaca taccatttac gttctacttc
     8881 gcctggtttg gccatatatg ttgtacgcac gttattttcc tccaatttaa gttctgatgt
     8941 ttgacataca cttcgagttt ccggggctct ttgtggggca aacaatacca tttaacatat
     9001 tacccgctaa tctagtcaat gtcaacgttt ttctgcttga ttgaaaaatt tatatgaaac
     9061 tttacttctt ttctttcttt tatataaaag ggtcgtttcc tgtcaaaatg aaaaacaaaa
     9121 agaggctgtg acaaaagtct tgtcacaacc ccttattttg aataaacggt gttctcctgc
     9181 caactcctcg gtcacaagtc acaatatcca taaaacataa gaagctgttt tttaaaattg
     9241 tttcttgtga ctcggagctg aacggcaggc t
//
LOCUS       DADQCX010000097         9269 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.099, whole genome shotgun sequence.
ACCESSION   DADQCX010000097 DADQCX010000000
VERSION     DADQCX010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.099"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..668)
                     /locus_tag="J8R83_002316"
     CDS             complement(<1..668)
                     /locus_tag="J8R83_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9575432.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            802..1089
                     /locus_tag="J8R83_002317"
     CDS             802..1089
                     /locus_tag="J8R83_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575433.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1505..3043
                     /locus_tag="J8R83_002318"
     CDS             1505..3043
                     /locus_tag="J8R83_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAZ9575434.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3040..4005
                     /locus_tag="J8R83_002319"
     CDS             3040..4005
                     /locus_tag="J8R83_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575435.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            3992..5314
                     /locus_tag="J8R83_002320"
     CDS             3992..5314
                     /locus_tag="J8R83_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9575436.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5377..5481
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5555..6298
                     /locus_tag="J8R83_002321"
     CDS             5555..6298
                     /locus_tag="J8R83_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575437.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6313..7305
                     /locus_tag="J8R83_002322"
     CDS             6313..7305
                     /locus_tag="J8R83_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9575438.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7317..8054
                     /locus_tag="J8R83_002323"
     CDS             7317..8054
                     /locus_tag="J8R83_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575439.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8044..8766
                     /locus_tag="J8R83_002324"
     CDS             8044..8766
                     /locus_tag="J8R83_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAZ9575440.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8850..>9269)
                     /locus_tag="J8R83_002325"
     CDS             complement(8850..>9269)
                     /locus_tag="J8R83_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAZ9575441.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3028 a         1603 c         1962 g         2676 t
ORIGIN      
        1 cagtgctcta actgttcaag aggatcaagt ggttcaaatg tttctgtagt ctgttttgct
       61 tccaattggg gcaaaacaga tccaatttcc agatacttca ctttattcaa tgtataagat
      121 agaatagaac agctaagtaa tgtatacaga aaatgtgtga ggtccaaata aagcaaggag
      181 acaactaaaa taccaaaagt aatcaagaaa agacttttgc caatcttaat atgaaaatat
      241 ttttcaatgg cttgataaat gatatctgtt ccgcctgtgc ttccgccgaa tcgaaagacg
      301 agaccgcaac caatgccaga aagaatacct gtcatcaaac tattgatcag tagactatct
      361 acagcaaaat gtatatgaag gctctcccat aaatgtaaaa agaaaactag cgcaaatgtt
      421 ccgacgatcg tccggagaaa agcgtgtttt ccaaaaagaa acaatgagat aagcaataaa
      481 ggtaaattaa aaagcagtga agtgacagaa ggagcgaatc caaaaagatt atgcaaaagc
      541 aaagcaatac cagtaacccc accatctgcc agcttagatg gaatattgat tcctgtcaca
      601 gctaatccgt agattcctgc gcctaaaatg attccgcaca attctgtaaa taaatttaat
      661 tttttcattt ctagcctctt ttcttttgaa aattttcagc aacttcttta ttatactgac
      721 ttatactctt acttcaagag gaaaatgaaa aaaaattatt tttggctgtt tctttttatt
      781 tatcaaataa ggagtggaaa aatgcgagca gcagacttat tgacaattct tacaaaatca
      841 cccaaaaaaa cagagtatca aggagttttt ttggctcaag aacaaaaact ggtgcctgtg
      901 acaatggtcc agataaataa agcaaatcaa tttatctttt tatttgaaca cggcaaagca
      961 ccacttgcta tgaaagacat ctttcttttt ttgatgaaga accgtgagaa agctgtttat
     1021 tatcagtcaa aagaagaact cattcctctt tatggagtga aagagataga aaataaagtg
     1081 gtgatataag taaaaataag aaaacaagac gtttatgatg tcaaaacaac cattttttac
     1141 atttttggca aaaaagtgtc atgatacagt ataatattcg ttgaacaggc caataaaggt
     1201 gttctccccc acgagatttc tactttattg gctgtttctt tttattaaaa taaaagttgt
     1261 gtgtgtaaaa aagatatagc tgattccaag tgacaatttc gtatagattt ttatggtatt
     1321 cgtagtgaaa aaacgagaac caaaaagttg atccgacttt gttgcttgga ttcttttttt
     1381 gtcagcatat ttagaggtat ttttttcttt tttttgttcg tgctgtaagg ttaaggcaag
     1441 acaagttagt tgggaaaaag gaaagaaatg tttatactta aagaataaca gaaaggaagg
     1501 tcgcatgaat aattttatac aaacattaag tgaaagaaaa ggcgagttgc tggaagctgc
     1561 atttcaacat ctgtccattt ctctcatttc tttgctgatt gcagcactga ttgctattcc
     1621 tttagcgatt tgggcagcca atcataaaaa aatggcagaa gtcttattgc agatcacggg
     1681 tgtgctccaa acgattcctt cacttgcctt attaggttta cttatcccat ttgtagggat
     1741 cggaactgtt ccagcattga ttgcacttgt tatttacgct ttgcttccga ttttccaaaa
     1801 cacgtatatt ggtctagctg aaattgaccc gtctattgaa gaagcagcgg tagcatttgg
     1861 tatgtccaga atgagacgct tgctgaaagt agagcttccc atcgcattac ctgtcattat
     1921 ctcaggtatc cgaactgcct tagttttaat catcggtacg gctactttgg cagcattgat
     1981 cggagcaggt ggattaggga catttatttt gttaggtatt gaccgaaata cacctgtttt
     2041 gacattgatt ggtgcgatca gttctgcctt gcttgcaatt atattcagcg gactgattcg
     2101 ctggttgcag cataagaaac ctcgatattc catcattact ttagcagcag tggtgtgttt
     2161 atttggcggc gtttctttat atcagtctgc cttgtttaaa aatgaaacca tcacgattgc
     2221 tggaaaatta ggagcggaac ctgaaatcct gatccaaatg tataaagaat tgattgaaga
     2281 caacacaaaa acagaagttg aattaaaacc gaattttggc aagacgagtt ttttgttcaa
     2341 tgcactggat caaggtcaaa tcgatatcta tcctgagttc acaggtactg tcctagaaag
     2401 cttggtgaag gtacctgaag caatgaaaag tgctgatttg acaaaagaaa aaacatatga
     2461 cgaagcagaa gaattattga ataagcaatt cgatatgaca ttattaaaac caatggctta
     2521 ccaaaatacg tatgccttgg cagtcaagag atcttttgcg aacgaacatc aacttaaaaa
     2581 gatttccgat ttggcagcta tctctgatca gatcaaagcg ggattcacac tggaatttat
     2641 tgatcgttca gatggatata aaggaatcca agaagcatat ggcttgaatt tttcaagtgt
     2701 acaaagcatg gagccaagtt tgcgttacca agcaatcaat aatggagatg tcaatattgt
     2761 ggatgcctat tccacagata gccagctcaa ggagtacgat ctagtgactc tagaagatga
     2821 tcgagggtta ttcccagctt atcaaggcgc accgctgatg aaaaaagatt ttgctaaaga
     2881 acatcctgaa atcgttaaag cactgaataa attaagcgga aaaataacag aggatcaaat
     2941 gattgatatg aattaccaag tcaatgtcga aaagaaaaag ccgacagaag tagcacgaat
     3001 cttcctgaaa aatgaaggat tagtaaagga ggaagatcag tgactaaatt aatcgagttc
     3061 aaacatgtgc aaaaaaagta tgatggaaag tatgtcatcg atgacctaaa tctggcaatc
     3121 aaaaaaggag aaatctttgt tttggttggt ccttccggta gtggaaaaac aactactttg
     3181 aaaatgatca atggattatc taaaccatca gcaggagaca tctacttcaa aggaaaatcg
     3241 ttaaatgaat ataatctgca gaaaatgcgg tggaatatgg gatatgtgct gcagcaaatc
     3301 gctttgttcc cgaccatgac agtcaagcaa aatattgaag tcatccctga aatgttaggt
     3361 tgggaaaagc agaaaagagc agaccgtgta gatgaacttc ttcaaaaagt tggcttatct
     3421 cctgatattt atcgagatcg tatgcctaga gagttgtctg gaggagaaca gcaacggatc
     3481 gggatcatcc gagctattgc tgcaagccca gatgtgattt tgatggacga gccatttagc
     3541 gcattagatc cgatttcaag aaactcatta caagaattgg ttttgtcctt acacgaagaa
     3601 ttgggcacga ccatcgtttt cgttacgcac aatatggaag aagcaatcaa gctaggtgat
     3661 cgtattgcat ttatgaagga tggagaaatt atccaatgtg acacaccaga gcagttattg
     3721 atgaatccta aaaacgacta cgttcggcat ttctttgatg aaccgaaaca gacgaaagag
     3781 tggcgagtag aagatttagt cgtcaatgga tatttcttaa atgaaatacc agaaaatgct
     3841 cgtcaacaag tttgctttga tacgcctatg aaagaagtat attcgcttct ttcggtgtat
     3901 ccaagcattg tgatagtaga aaagcaaaga agtattgggt cgctgacaag taaagaaatc
     3961 tttgcttttt taagtcgaga ggaggaagga aatgaaaaca tatgatgcaa tcatcatcgg
     4021 ttcaggtgtg agcggcttaa gtgctgctta tggattgaaa gaagcaggta aaacagtact
     4081 agtggtcgaa gaagatctat ggggcgggac ttgtcctaac cgtggatgtg atcctaaaaa
     4141 agtcttgtta agtgcagtag aggcacgtaa tcgggtaaaa caattgagtg gaaaaggttt
     4201 taacgagatc ccaactgcca actgggaaga acttcaaaaa ttcaaacgaa catttacgga
     4261 tccagtccca gaaagccgaa aaaaacaatt agcagaagct gaaatcgatc atctttcagg
     4321 aaccgctcgt tttttggatg attcatctat tgaagtcaac gaagaagtct tccatgcgga
     4381 ttacttagtt ttggcaaccg ggcaaagacc tacgatctta ccagtggagg gaaaggaata
     4441 cttgaaaact agtgcagact ttttatcatt gcctgtactg cctaaagaaa tcatttttat
     4501 cggtggtggt tatattgctt ttgagctagc tacgattgcc aatgctgcag ggagcaaagt
     4561 aaccattgtc catcataatc aacggccatt aaaagaattt gaggcgtctt tggtagagga
     4621 agccgtccat caaatggaag catctggcat tcagtttgct tttggtgttg aaacccaaaa
     4681 gatcatttca gaaggtactc gctatcgttt agtcggaaaa gagacggaat tagtagcaga
     4741 tatgattttt tgtgcgactg ggagacagcc gaatacagaa tctttagcac ttgagcaagc
     4801 gaatatcgtc tttgataaac acggaattgc agtcaatgat tatctgcaaa cgagcaatcc
     4861 aaaaattttt gcgtgtggag atattgtttc aaggaaaacc ccaaaattga caccagtcgc
     4921 cacttttgaa ggaaattatg tagctaagcg gataacggat gcaacaagcg aacctatcaa
     4981 atatccgatt atacctacga tcgtctacgc cagtcctaaa cttgctgaag taggagttac
     5041 aaaaagtcac gcctcttcgt cagatcaagt ggtagagatg gatcttacca gttggttcac
     5101 ctatcatcgt gtcaatgaac cagttgctaa ggctgaattg acctttgacc agcaaaatta
     5161 tttgattggt gctgcagtga ttagcgagca agcagacgaa ttgatcgatg atttgacact
     5221 cgtcatcaat caaaaattga ctaaaaaaga gttggatagc tatatcatgg ggtatccgac
     5281 attggcaagt gatctctcct atttattgaa ataatcagca tgataactaa agcgcttgtt
     5341 gctttttcct tcttgtgcta cactttaaaa aatgaatacc tgtttctggg gatgtcgtag
     5401 acgacatgag agtaagttgt gaacttagac ccattgaacc tgtcagttaa tactggtgaa
     5461 gggagaaaca tagcagacgc ttgaagcggg ttactatgtc gtgcccattt caagcgtttt
     5521 ttgttattca tattagaaga aaggaggtaa caaaatgaag aaaaatcttt atccagcagt
     5581 cagtatggca ttcattttaa ttatttggca gattgttgtc atagtttgga aaatacctgc
     5641 ctttatttta cccggacctg ctgctgtatt ttctgcatta gcggcagatg cacaagtatt
     5701 actttcccat tctgtcacga cattaaatga agcagtgctt ggtttggtaa tagctagcgt
     5761 tctttctttt attactgcct tggcaatgga ttattggaag tttttagaaa tgtcttttta
     5821 tccgttacta gtgatttcac aaatgttgcc aatcatggtg ttagggccat tacttaccct
     5881 atggtttggt ttcggtatgc ttccaaaagt gatccttgtt gtcttgataa gctattttcc
     5941 gatcgtagtt tctttttcgg atacattgag gaaagtatca aaagagcaaa tcatcttttt
     6001 gaaaacgatg ggggcagata cagggaagat ttatcgaata tataaaatac cagcgggttt
     6061 atccggcttc ttttccggtt taaaagtggc tgctacttat tgtgtcagcg gagcagtcgt
     6121 tggagaatgg ctaagcgctc aagcaggctt agggtattac atgatacgcg taaaaaacag
     6181 ctaccagatc gataaagttt ttgctgcgat catttgtgtc attctattga gtttattgct
     6241 gaatggcgct tgttcattat tgaaaaaagg gtattatcgt atgctttata ttttttaaga
     6301 gaaggggatc aaatgaaaaa attatggctt ttattaccgc tactgttgct tttatccgct
     6361 tgtggcactg caaaagaaac aagtagcaaa caagaaataa aggatttgaa aaaagtgaca
     6421 cttgttttgg attatgtacc gaatactaat catactggca tctacctagc aaaagaaaaa
     6481 ggctattata aagaggctgg tttaaatgtc caaatcatcg aaccaggaga taattcgaca
     6541 agtattggtc tagtaggtgc ggacaaagca caatttggtg taagttatca agaagatgtc
     6601 acttatgctc acgcagatgg acagaatata ccagtcaaag caattgctac agtgatcaaa
     6661 cataatactt ctggattcgc caccctatca gacagtaaca tccattcacc aaaagatttt
     6721 gaaggaaaaa catatgcagg ttggcaaagt ccaagtgaag aagctgtctt aaaagctgtg
     6781 atggaaaaag acggcgggga cttttcaaaa ctgacaatgg taggaagcaa tggagaaggg
     6841 ccagaaagct taggaaaatc ctcagatatc caatggtact ttgaaggttg ggatatgatc
     6901 aaagcaaaag aagcgggtat tgaactaaac tatatcccat tgaaagaatt agatgaacgg
     6961 ttagattact atactccggt aattattacg aatgatcaac tgatcaaaag tgatccagaa
     7021 ttggtacagt cttttatgga tgccacgaaa aaaggctatc aggaagctat taaggatcca
     7081 aatgacagtg ctaaactgtt gcaaaaatat gcaaaagaaa atgatcggac gtttttagaa
     7141 gaatcacaag cattcttgtc aaaaaattat acggatgatc ctgagaattg gggattgatg
     7201 gaagaaaaag tttggcgcaa ttatacagct tttatgcagg aaaacggatt gatcaagcaa
     7261 gatgtacctt cgcaagaact attcactaat cagtttataa aataggagtg atagatatgt
     7321 caatccaaat cagccacttg aatgtagtca ttgaaaacct gaaaatatta gaagacatcc
     7381 atttcactat ccctaaagat acctttacat cgattgtcgc gccaagcgga gccggtaagt
     7441 caacattgct gaaaacttta acaggagtcc agcctatgac ttctggaacg atcaaagtag
     7501 acgatcaaaa agtaactggt ctccatacag catttagtta tatgccgcaa gaagatatgt
     7561 tacttccttg gctgagcgtc tatcaaaacg ttacgttata tcaaaaaatc aatcatctaa
     7621 caatcaatga agaacaagta agggattatc tggatatctt tgggttaaac ggctatgaac
     7681 attttttgcc ggaacaatta tctggcggga tgaagcagcg aacggccttg ttacgaacaa
     7741 tcatgaatcc ttcttcttac ttgcttcttg atgaaccatt tggagcgtta gatgctatga
     7801 ccagagggca gatgcaagac tggatgttga agctgcctaa aaaagcaaag cggactactt
     7861 tacttgtgac gcatgatatc gaagaagcaa tttatttatc agacaggatt cttgtgcttt
     7921 ccgcccgtcc ggcacatgtg attgctgaga ttcaagtgcc tgaaaaacga cggtcacgtg
     7981 aatggctact gcagcaatca gagttgaagc aaacgattta tcagttattg gcaggtgaat
     8041 tagatgttaa gtgatgctca ttgtcattta gatgggagtc agagtttagc actccttcag
     8101 caggaacaca cgattttgac gatcatcaat tgtgattcgc cagaagaatg gaaggaaaac
     8161 agacagcttg cagcaagtaa gactcaagcc ttaagttacg gtatccatcc ttggaaagca
     8221 gatagctata cgtttgaaca agttgagcct tttttgaaaa aagcaaggat catcggtgaa
     8281 atagggttag ataatatttg gacgaatgta ccgatgacta cacaaaaaaa agtatttgag
     8341 cgacagcttg cttttgcagc cataaatgag aaacctgttg tactgcacac aaaaggatgc
     8401 gaaaaagaga tcttaaatta tatccaagct taccctaatc actatttgat ccattggtat
     8461 tcttctttgg actatcaaca agactatatt gatttaggct gttatttcag cattggtctt
     8521 gatttgaaaa agaatccagc agtctggcaa ctagctaaag cagtcccaat cgaccactta
     8581 cttattgaaa cggatggact acatgcagca gagtgggctt taggggggat tttttcagaa
     8641 aaagattatg tctcactgct tgaagaacag ttaaagacaa tcgctgagat caaagagcta
     8701 tcagttgaag aagttaaaaa aaatacttat caaaacttgg aacgtttcat tagattaggt
     8761 aaataaaaaa gagatgtgac acaactagtg tcgcacctct ttttggcttt ctttgtataa
     8821 aagtaaactg tttgattaat aaatgaatct tagtaccaac cgtttgcttc ccagaatgct
     8881 ttcgccgctt cccaagaacc ataacgtgaa gtaacatatt gttctgctac tctttcttgg
     8941 tttgcagcag agtagtcacc atttaagtaa gaagaatcta attggtaacg tccgatgtaa
     9001 cgtccgttcg ttgctgtgta agaaccgctt gattcttttt gtgcgatcca ttcttttgca
     9061 gagcttgtgc ttgctggagt agcagcagtt tctgttacag caggagcagg ttgtgtttca
     9121 gcaacaggcg ctgcttgttt ttccgtttga accgtttctt gtacaacagg ttgttcagct
     9181 tggactggtg cttcttgaac ggctgcttga ggttcagcag ctgcttgtgc agagccttct
     9241 gttgggattg ttaattgttg tcctgagta
//
LOCUS       DADQCX010000098         9216 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.100, whole genome shotgun sequence.
ACCESSION   DADQCX010000098 DADQCX010000000
VERSION     DADQCX010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.100"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..104
                     /locus_tag="J8R83_002326"
     CDS             <1..104
                     /locus_tag="J8R83_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAZ9575442.1"
                     /translation="FQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(172..465)
                     /locus_tag="J8R83_002327"
     CDS             complement(172..465)
                     /locus_tag="J8R83_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAZ9575443.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(493..1158)
                     /locus_tag="J8R83_002328"
     CDS             complement(493..1158)
                     /locus_tag="J8R83_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAZ9575444.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1298..1930)
                     /locus_tag="J8R83_002329"
     CDS             complement(1298..1930)
                     /locus_tag="J8R83_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9575445.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1937..3004)
                     /locus_tag="J8R83_002330"
     CDS             complement(1937..3004)
                     /locus_tag="J8R83_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9575446.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(3001..3732)
                     /locus_tag="J8R83_002331"
     CDS             complement(3001..3732)
                     /locus_tag="J8R83_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAZ9575447.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDIEVIRI"
     gene            complement(3900..4379)
                     /gene="greA"
                     /locus_tag="J8R83_002332"
     CDS             complement(3900..4379)
                     /gene="greA"
                     /locus_tag="J8R83_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAZ9575448.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4515..5690)
                     /gene="mltG"
                     /locus_tag="J8R83_002333"
     CDS             complement(4515..5690)
                     /gene="mltG"
                     /locus_tag="J8R83_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAZ9575449.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            5855..7015
                     /locus_tag="J8R83_002334"
     CDS             5855..7015
                     /locus_tag="J8R83_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAZ9575450.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(7055..8002)
                     /locus_tag="J8R83_002335"
     CDS             complement(7055..8002)
                     /locus_tag="J8R83_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAZ9575451.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(8035..>9216)
                     /locus_tag="J8R83_002336"
     CDS             complement(8035..>9216)
                     /locus_tag="J8R83_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAZ9575452.1"
                     /translation="ILVITSFVHKEYGLGENLKTIMWAILQYFLIYQFAFENSDNKRF
                     FKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHRIRIGFLESRLFGTFSDINNA
                     AIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIYIVLSGSRSTYVVSIIIVAIS
                     SFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNATKILFQELLPHLKEINFFNF
                     TERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNARITIWKSAWEIFKTSWLIGV
                     SPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGILGIIPFMAFLIKSFVLNVYR
                     IIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTVGTFVFWLFLGRVNSKNNSSY
                     F"
BASE COUNT         2842 a         1880 c         1398 g         3096 t
ORIGIN      
        1 attttcaaaa gaaattaatg gctatttttt taaccaatct gaaaagctac tttgccaccc
       61 atgagcttca aaccaatcaa gtaaaattgt ctgcaggata ttaatagctg aaaacaatat
      121 tttcaaaaga aaaaagagaa ggtgacaaaa attgtgtcac cctctctttt tttattgttt
      181 tttaaagtga taggttggct cctccaggtt gggatcataa tcaacaagta aatcatatcc
      241 tttaaagaac cattcatctg cttcctcgat aaaaaaaagt gtcccatcca tttccacttt
      301 ctttacagga tgttctggct gttcaactga cattccaatc gaaaaaccat catgaacctc
      361 tgttttgccg tagacttttc caaaaaaacg tattccgtaa gtttctggca gatcaatttc
      421 tgagtcaaac cacttttgtg cttttggcgt taccgttaat ttcatcccaa caacctactt
      481 tctcttttct ttctattgat tcatcttatc gtctagaata tccacatcgc ctgtctctcc
      541 aataaccagt agattatcat tttcacgaac atattcatct gctgcaggag aagcgataac
      601 cgtttgatct actcttcgta tggcgactac tgttaagtca aaacgttgcc tgaaatttaa
      661 ttcagctaat gttttgttga aaaatttagg attggagact cggatttctg ctaaagaata
      721 tttatctgac agctctaagt agtctagaat attctttgat actaagttat gtgcaatccg
      781 tatccccatg tctcgctcag ggtgtacgac acgatctgct ccgatcttct ctagtacacg
      841 ggcatggtac tcattttggg cttttgctaa aatattcggt acgcccattt cctttaccat
      901 cagagtaact aagatgctgg cttggatatc ttctccaata gcgacaatta catgatcgaa
      961 atttcttata cctaatgaac gaagtgtcat ctcatcctgt gcatttgcca caacagcatg
     1021 ggtggctata ttcatatatt cattgactcg atcttcatta ctgtcaatag ccagtacttc
     1081 ttgtccagct tcgatcagtg tacggcagat gcttccgcca aatcgtccaa ggcctacaat
     1141 tgcaaaattt tgtttcacca ttttcctcct ttagtatctt cttttctcag tataacaaag
     1201 cctttccaaa aacaaaagca agcatcatta ttgtaaaaaa gccaagaaaa ataatagtta
     1261 ttttctcagc ttttgattat cctctttatc atcgttttta tttcaccaaa ccatgtttaa
     1321 acgcatagat agctgcttga gttcggtctt ctacctctaa cttagctaat atattcgaca
     1381 catgcgtttt gactgttttc agtgtgataa acaattcatc cgcgatttcc tgattacttt
     1441 tcccttcaga aatcagcatc aaaatttcat tttctcgatt cgttaattct tcatgcaata
     1501 ctggatcatt tcgccgactc attttttcca tcatttttgt tgtcacttca ggttctagta
     1561 ctcgctcgcc gcgttgcgta gcccttatag catcagctat ttcatgtgct gtagacgtct
     1621 tcaacaaata tcctgctgct cctgcttcaa ttgcaggata aactttttca tcatcaataa
     1681 aacttgtgac gataatgatt ttggcttttg gccaatcttt taagattgct tttgttgatt
     1741 cgatgccatc catttcttcc atgactagat ccattaaaat gacatccggt cgaagtgcca
     1801 tcgccttttc atagccttga cgtccatttt cagcttctcc aatcacttca atgtcttctt
     1861 ggatagataa ataagaagag acgcctaagc gtaccatttc atggtcatct actaataaaa
     1921 cttttatcat ctttatctat gcctccttca tcaaagggac cttggtctcc acgctcgtac
     1981 cttgcccttt aaaactaatg atttttactg ttccaccaat accagctact cgttctttga
     2041 tattgttcaa tccataactt cccgttttgg tttcattcat attaaatcct gtcccgtcgt
     2101 caatgatacg taataaaaga ttgttatcta ttttatgcaa atagacttct aattcattag
     2161 ccttagcatg tcttaatgtg tttgataaca attcttgaac gattcggaac aagtgatcct
     2221 caatggaact agttaatttt acatcttcta cctcccattt tagcgaaatc tggattttat
     2281 tctgcaattc cttcaataac tgctcaatgc cttgttttaa acttttttct tctaaattga
     2341 ctggacgcag atgaagaagc agcgcacgca tctcagactg ggaagcgttg atgatctctg
     2401 ccaccatttt caactgctta cggaacattt ctggtgtctc acttttttct gcttgctccg
     2461 tcaatgccga catcatcatc atcgctgcaa ataattgctg tgaaactgaa tcatgaagct
     2521 cacgagctaa tcgatgcctt tctaatttta aaatctcttc tttggtttgt ccatctacat
     2581 attgaggacg gctagtcata atctgtaatt cactggatac ttcgatcatt ttttctttta
     2641 ttttagtaat ttccatatca atatctttga tgtacagatc atccgacgcg cttgggatcg
     2701 gctgatgcaa aagtttggat tcataattgc cagaagaaag tgcacgaagc ttttcttcga
     2761 ttttcccgta ttttgccttt tgaataagtg ataacaatag aaatacgatc aatcctacac
     2821 ctaatgaaat tgccatcaaa tggaagataa gcggaacgta taataaacgc gcacgcagca
     2881 attctcccca ccaatgactt tggttactgg cataaaaata agtgaaaagt gaaaatagaa
     2941 taataaggaa agccgcaatc cccgaataaa cagctagcat tgctttggat attcttccca
     3001 tcatattcgt atcacctcga tatctccaac caaagtattg gtaatgatct tcaatctgcg
     3061 aggattttca tcataatcac tgctgcagat tttgatctgt tcgtttttta aggaaaactg
     3121 ctcttcttca aacaagacat ttcctactaa tgtcgcatgc tctaaacgaa tagccactcc
     3181 caggggtact aagatccgtg ttctgcctat cccttttctt acaatcacaa tattatcatc
     3241 ttttggcaaa agtgtattgc ccaaatcgat gatagtatca ccagaaatga tggcaatgtt
     3301 gatatcatcc cattcataga cgtcgtttcc aatacgttgg ttaccaaata attgctgtct
     3361 tttacgctca ttattatgtg tttttaattg ctctgtttgg accatcatga tctgtttttt
     3421 tcgccaaaaa gcattttttg tcaaatctat tcctgaaatc tctacacctt tcagcccgat
     3481 aaataaaacg gccaatacaa ccatcatcca taaagcagga ctgttgacta agctaaaaaa
     3541 aatgaccaag ctccctaaga tcaattgaaa attttgaaat ttagtacgag gatatttgcg
     3601 catagctaga tatatattga aaataccgaa tattactaaa agcaaaagtc cagtattgtt
     3661 tacgatttgc caaacagcaa ataacagcag cagtgcttcg actaccacaa aaaaacgcca
     3721 agaactattc atcgcttttt ctccctcctg acacattctc atttcatcat acctattttt
     3781 ttgactgttg gctataggac tttagatgta agatcgttca gtgaaacctg caatactcaa
     3841 agagaaaaga tctagagtgc gtcatcagta agatgaactc tctagatctt tcagtcagac
     3901 tacgcttgtt ctactttgac gattttaact aacatatcgc cacctggtgt agcaatggtt
     3961 acttcatcat ttttacgttt gccaatcaat gcttgcgcga taggagaatc attggaaatc
     4021 tttccagaaa acgggtctgc ttcagcactt ccgacaatcg tgtactcttc ttcatctcca
     4081 tcaggcaact cgatgaacgt aactgtttta ccgatcgata cctcatctgc atctacgccg
     4141 tcattatcga tgatttgtgc aaaacggatc atattttcaa ttgttgtgat tcttccttca
     4201 acaaatgctt gttcatcttt agctgattcg tattcggagt tttcggaaag atctccgaaa
     4261 ccgcgagcga ttttgattcg ttcaatgatt tctccgcgtt taactgtttt tagttcttct
     4321 aattcttttt ctaatttttc tttaccttct agagtcattg gataaacttt ctctaccatg
     4381 tgtaacgtct ccttttttcg ataaaatacc gcaaaaggta atcttttgag gaatatagtc
     4441 caaaaaagat taccacgctt ttcttaaaat gtaaatgttt ttctaaaaat gatcaatgac
     4501 tagcccctgt ttttctaaga attatttaca tatttttgca ctagttccat atgttcttca
     4561 tacgttttag cgaaataaac atttccagtg ctcgtatctg ctacgaaata ataatagtca
     4621 ttttctgctg gttctaatac tgccttgatt gcctcttcgc ttggattgtc aaaaggacca
     4681 ggcccatagc cggtattggt atacaaattg tatggtgaat ctacagctgt atcttcatac
     4741 gtcaccaatt ctttatgttc tcctaatgca tataaaacag agatatctga ctgaagtggc
     4801 atatttgcct tgattcggtt aaagaagact tgtgcaatat ttttacgatc attttctttt
     4861 acgccttctt tttcaactag agaagccaaa gttaaaactt cttgtacagt caaatttttc
     4921 tgtttgatag ctgaataata gttttgcatg accgtatttg ttttgttcac catctcaatc
     4981 acaagatcct taagcgaagt actcgtgtag taatcataag tagctgggaa taagtagcct
     5041 tccaaacggt attttgtgtt ctcagcttta gaggcacttt ccaacaattc tgggaatttt
     5101 tgatacaact cgttaaagaa agtctcatca tttactaaat ctaaaaattc tttcttgtct
     5161 ttaccagtta ccttcgctac ccgctcagca atctgatcga tgtcgtagcc ttctggaatg
     5221 gcaattttcc catctgcaac ttttgttggc tcagatgtgc cgccttcttg caactgcttg
     5281 ccaatctcat caagagtcat attaggcgct aactgataat aaccagcttg aaagccagtt
     5341 aagtttttaa attttgtata ataattgaaa acaatcccac ttttaataat attgtctttc
     5401 tccaaaattt cgccaatctg cttattagaa gagccgcttg ggatttccac ttggactaat
     5461 tggtcgtccg atttatctaa aggcttcaac ccgctatcta cataacgata tacggtaaac
     5521 ccgagaaatc cgccaataat caataatgta agagcgatca ctaaaatgat cttcctcacg
     5581 atcttatctt cttttttacg cagatttctc cgcttgtcga ttatatctgc tgtagctgcc
     5641 ttactggctt cttttttgtc tttgcttggg tgttgtttgt ttcctgacaa aacaactcct
     5701 ccttactatc atcttcgtaa ctctgtttat tatacatgaa atttctactg ccgtgaatta
     5761 ttttaccaaa tattatgtca aaattgtaag tggcaaatgc tctttttgag gattacaatg
     5821 aaaaatagtt aaaaatggat aggaaggatt taatatggca aaaggaaaac atcaaaaaaa
     5881 acagcagatc tctctttctt ttctcgcagt tttgttgctg gctgtcagct tcttttcaac
     5941 aggcatcatt acaggatggc aattaacaaa acaacctcaa ccacaaattt ataaaacgga
     6001 acccgcacaa cttgcttcca atttaacatc taatgagcag atgcttgcca gcaaaattga
     6061 tcaattactg caaaaatcag attatatcgg ttcgatttat gtacgcaaaa ataatcgagt
     6121 gatattagaa aaaggatatg ggtacgcaaa tctacgcata aaagaatcga attctccttc
     6181 tctttactat caaatcggtt cgatccaaaa agcgatgact gctttactta tcctaaaaca
     6241 aattcaatct ggcaagataa cttttgacac aaagctatct gaattttatc ctcagattcc
     6301 tggaagtcag caaatctcaa tcaaaaatat gctttacatg cgctctggtc ttcatcgaac
     6361 cgcttctcca aaaaaaccta tgtcagatag tgagatcatt cagtttgccc ttcatcattt
     6421 gaaatttact ggttatgata cgtatcatta tgaaccatta aattatacat tgcttacagg
     6481 ggtattgatc aaactaatga atcagcctta tgaaactctt ttaaaaaaag aaatcattcg
     6541 gccactccat ctagaacata cagattttta tgaaaatgta aaaaattccc ctcagcatgc
     6601 tgtatcttac caaatgtctg caactgacga ttattcaaaa gcattggtcg agcctgaaac
     6661 agacatccga aatgaattag gcacaggaaa tataagtatg tctgtttatg acttgaacaa
     6721 attctttacc agtgttctgt ctggcgatat tataccaaaa gaactacttt tctcattgtg
     6781 gcaaaataat ggtgataaac atccttacag cggcggtgtt tacagtggaa atgattatat
     6841 ccttgctcag ggaaatatca atcgattcca tgcagtagcg gcgatgaaaa aagacacaaa
     6901 agatgcaatc gtcatggaaa gtaatatcca atctgataaa aacatcaaat tgccggccac
     6961 tgatttaaga aatcagattt acgaactgat ggaaggtgtt aatttaaaaa gctaagtcga
     7021 gacaaaaaaa ccagcaggat gctggttttt tgtttcaatc gatttctgtc tttaaataac
     7081 gttccattcc gttcaatata tcaaatttgg gttgataacc taaagaacgg atctttgaaa
     7141 tatccgctaa agaatcacga atatcccctg aacgctccgc ttcatattta agcgctagct
     7201 ctgttcctaa gatttgatca attgaatgaa tcaattcaag tagcgtagtg ctttttcctg
     7261 taccgacatt gaattgctgt cctaaagctt tttcttcctt agcaacaagt aaaagtgctt
     7321 gtataacatc ttctatataa acgaagtctc tagattggct accatcacca aataaagtaa
     7381 attctgtttt ttctcctgcc aattgttttt tgtatcggtc cactagaatc gaaataactc
     7441 cgctatatgg agagttagga ttttgatttg gaccataaac gttaaaaaat cggacagcac
     7501 tagtcggaac atcatataaa tgacagtaat ccaaaacata ttgttctgct gcaaacttat
     7561 cgatggcata tggtgttaaa ggacggatga ccgattcttc tttttttggc aacgttggtt
     7621 catcgccata aactgcagct gatgaactaa ataccaatcg ttttaaacca gattgatatt
     7681 ttcgtaccaa ttcaagcaat aaaagcgcac tgtcaaaatt tacacgatga gtttctagag
     7741 gacgttctac agaatctgcc acactagcta cagcagctag atggaaaata taatcgaaat
     7801 ggtattcttt catgaccttt tccatcaaat ttttgtcagc gacatcccct tcaataaacg
     7861 tgatgtgctt cgattcatcc agattctctt ttttccccat cgataaatca tcgatcacaa
     7921 ctacattgtt ttcttttcct agataattcg cgagcgtcga gccaatgaag ccggcgccac
     7981 cggtaatcaa gtaattcaac attttttctc ctcttttcaa gataaaattt attactaaaa
     8041 atagctagaa ttatttttgc tattaactct tcctaaaaat agccaaaaaa caaacgttcc
     8101 tacagtgttt tcatagacta attcattgtt aagagctgcg tatagtgcat aagataaaat
     8161 aactaaacag taaacaaaat gataatcttt accaatgcat ttattataga tgattcgata
     8221 aacattcagc acaaaactct ttattaaaaa agccatgaaa ggaattattc ctagaatacc
     8281 tgtcgatgtt aatacattca agtatgcatt atgaatggca attcctactt tcgcaatata
     8341 tccatctgga ataattgact gtgcataaga tactacattt ttcggagaga ctccgataag
     8401 ccaacttgtt ttaaatattt cccatgcact tttccatata gtaattctag cattagaaat
     8461 atctgtattt tcagctacgt ctttcctaac aagagtatta tcaggtgttt gagtattatt
     8521 aatatgttga ctattattca ttaattcttt atgacgctct gtaaaattaa aaaaatttat
     8581 ttcttttaaa tgaggtaata attcttgaaa aagtatctta gttgcattaa acaaagcgaa
     8641 taaaatcaga acagaaccaa tagaagatac tatagcaagg atatagtttt ttaaatcttt
     8701 ttttgttcca tttcgtttta acacaacaat aaaagatgat atggcaacta ttattatact
     8761 taccacatag gtagatcgtg acccacttaa tactatataa ataaattgta atggaagatt
     8821 aattaaaaaa atgattttat ttaatcctgt cactttttta ttataaagat aaaataagat
     8881 taggacaata acaactaaag atgctatagc agcattgtta atatcagaaa acgtcccaaa
     8941 cagtcttgat tctaaaaaac caattctgat cctatgtcta gcattataat atttctcata
     9001 gccgaattta ccaaagaaaa gaaccattga cattgatact aaaacaaacc aactataaat
     9061 aaatccccaa cttatccttt taaaaaatcg tttattatcg ctattctcaa aagcaaactg
     9121 ataaatcaaa aaatactgta agattgccca cattatagtc tttaagtttt ctcctagacc
     9181 atattcttta tgaacaaaac tcgttattac taaaat
//
LOCUS       DADQCX010000099         9090 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.101, whole genome shotgun sequence.
ACCESSION   DADQCX010000099 DADQCX010000000
VERSION     DADQCX010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.101"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            876..1349
                     /locus_tag="J8R83_002337"
     CDS             876..1349
                     /locus_tag="J8R83_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAZ9575453.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1358..1585
                     /locus_tag="J8R83_002338"
     CDS             1358..1585
                     /locus_tag="J8R83_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575454.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2221..2592
                     /locus_tag="J8R83_002339"
     CDS             2221..2592
                     /locus_tag="J8R83_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575455.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2848..3090)
                     /locus_tag="J8R83_002340"
     CDS             complement(2848..3090)
                     /locus_tag="J8R83_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9575456.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3122..4024)
                     /locus_tag="J8R83_002341"
     CDS             complement(3122..4024)
                     /locus_tag="J8R83_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9575457.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4037..4225)
                     /locus_tag="J8R83_002342"
     CDS             complement(4037..4225)
                     /locus_tag="J8R83_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAZ9575458.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4239..4802)
                     /gene="amaP"
                     /locus_tag="J8R83_002343"
     CDS             complement(4239..4802)
                     /gene="amaP"
                     /locus_tag="J8R83_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAZ9575459.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4840..5733)
                     /locus_tag="J8R83_002344"
     CDS             complement(4840..5733)
                     /locus_tag="J8R83_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9575460.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5811..6749)
                     /locus_tag="J8R83_002345"
     CDS             complement(5811..6749)
                     /locus_tag="J8R83_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAZ9575461.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6783..7133)
                     /locus_tag="J8R83_002346"
     CDS             complement(6783..7133)
                     /locus_tag="J8R83_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAZ9575462.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7166..8068)
                     /locus_tag="J8R83_002347"
     CDS             complement(7166..8068)
                     /locus_tag="J8R83_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAZ9575463.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8061..8918)
                     /locus_tag="J8R83_002348"
     CDS             complement(8061..8918)
                     /locus_tag="J8R83_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAZ9575464.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
BASE COUNT         2543 a         1729 c         1500 g         3318 t
ORIGIN      
        1 catttttctt attcacttct ttggtttata ctattcttat aaataaaaac gaggtatgtc
       61 ctatgatgaa aagattgtac tattcattga tcataacgat tggctatttg attgtatcaa
      121 atctaggaaa tatggtattt ggtatcagta aagaattcag ttggactact acattatggg
      181 aatctctatt ctttttcatc ttcgtatttt tgttacaaaa ttatcgaaaa aaataaacat
      241 gtgccatcta tctgttggca catgttttag gatttatggt actttttatt cggcaatcca
      301 ttttattttt ctacttcttc ttaatacctc taacactttt gatttataaa ctaatccaat
      361 gcatctactt gcgcttatta agctatttca gctagatagt accaccccat gcgtcaatgc
      421 ttgattttcc ttttgtataa cattgtataa gcaataaagg acaaataagt ggtgattaca
      481 ccaaaccatt gaataagaaa aattctgata cgtaaataaa catgaacttg aaaaaattaa
      541 tgaatcggtt agctactacg tagttgtctt ttttctcata cagttctgtt aacttacact
      601 tctcttcgct agataataaa aaatcctcca actgtattgt ccaatataat cccaggcatc
      661 taaactagca ttatagaaga gacacacata gaatctaaaa taactggttt taaatgtttc
      721 ttacaatcaa aaaaagctgt taaatgcact ccacaccttc atactctatc attttttata
      781 aacgatatat ttttattgtt tttcgataaa aaatagttgt tttacaataa ttattctgct
      841 atattttagc tatcaaagat aaaagaggga taaaaatgaa atttaaaaca ttgctattaa
      901 aatttgtcgt tttaggtata agtgccgtat ttattttgtt cggcgtactt ttttatactc
      961 agatcgctac aagcgaaaaa ggattcaatt ttgattggca gaccacatta tttgtttctg
     1021 tcatttactt tgcccttctc ctagggatcg ttattgctta tttcttattg aaactattga
     1081 aaaaaatcga agataaccaa gctttttcca ctcaaagctt aaacatacta aaaaaaatcg
     1141 aacgaaccat tttgtttatt ggtttcgcct tttttggctt acttcctaaa tttatgaaag
     1201 tagcggattt agacgatgct ccaggtttga tgttggtagg aatcgctgtc gtattcattc
     1261 cttttgcagt atacacatta acaagcgtgc tggaaaaact gcttgaacat gcgattttac
     1321 ttaagacaga tcatgatttg acagtgtgag gtgcgacatg gcaattatcg ttaatttaga
     1381 tgtagtatta gctcaaaaaa aaatgagtgt gactgaattg agtgagaaag tgggcattac
     1441 gatggcaaac atctctattc taaaaaatgg aaaagcaaaa gccatccgtt tttccactct
     1501 cgaaaaaatc tgccaagttt tggagtgtca accaggtgat ttgttgacct ataaaaatga
     1561 ctcgaatact ataccagaag aataaaataa agtagaacaa acagtaaata aaaaataatc
     1621 tgaatgatag atgtgtgaga cttttagaag ttatttacgt ctattattca gattttttat
     1681 ttcgattgaa taccgtttta tctataaata agatatgtac tgactcatac aaagggggcc
     1741 ttttcttctc catgtactat cacttttcct gatacaactg gtttcctgtt acgttgtagt
     1801 tggatctgct tttagtataa tactttattc attccaccag actgatagca gtttgagcag
     1861 tctaaataat catgtagtat tacaggccat tctgtttcat accttgaagt gcttaaaact
     1921 tcagctaatg gcccattgtg ttaactctta ctccattctt ttttagtaag ctcccatata
     1981 tactgtaaag ccttctatat attatgtcat gttgcttttt aacatttact atgtagtttt
     2041 gataaaatga tttgaataac agtgatggac aattcttttt tatttttaac attattttga
     2101 taataatgat tatttattta aaaatacatt agataacatt tgttacgaca cgaaaaagct
     2161 tcacaaacaa atatcgttat tttaaaatga gggcgaactc acacaattag gaggaatagt
     2221 atgccattta ttgtttactt ttttctttca ttactcgtga tctatattcc attaccaaca
     2281 tttttcctgc tcgtcaatcg tctagcagag caacatgata cgattgctgc tcttacgaaa
     2341 ctttgtttac ttctatttgt ttgtctagat tactttacga gctattattg gctaaaacag
     2401 acaagagtaa aaaagagata ttatttcttc cttgtctttt tcaatctctt tgagtttctg
     2461 atccattgct ttttacttca tcagtatcat acgatccatt tgtggatcat ctgggttttc
     2521 aaagtggtcg tattattttg tatgttcacc tttcctatct caagaaaatt tagggaggca
     2581 ttgttttatt aaagaagctt ctctgtatca ataaagacac atttaaggaa aaacttttaa
     2641 aaatctaatt gggaatttgc ccgcataaat aagaggctgt gacaaaagtc ttgtcacagc
     2701 ctcttattcc gtataaacag tgttcaaaag cttgcatctt cgataatatg cccaaccaaa
     2761 tgaaaaatat gagaagctat ttttgtttgg ctgttcttat tacttgatga agaacagctt
     2821 tttcacgacc tctttttaaa agtcttttta cagttttcga gcaaagaatg atacgattag
     2881 tactaaaatg atggcaccaa tcaatgatgg cacgattgcc attcctgcaa tacttggtcc
     2941 ccaagaacct aataatgctt gaccaagtgc tgatccaact aaacctgcta cgacatttgc
     3001 aataatcccc atcgaagaac ctttattcgt gattgctcct gcaattgctc cgataattcc
     3061 tccgacgata agtgaccaaa taaatcccat gtttcgttcc tcctaatgtt ttacttcctt
     3121 attactgaac ccgtggttct gtattttctt ttactttttg tgcgccgctt ccagctgctg
     3181 attttacttt atctgtttga ttcgaagcaa attcaccggt ttttttcgct gcgtcagtta
     3241 ctttgtcttg caccgtttct tgatcttttt caaattcttc ttttgttttg atgtccacta
     3301 cgttagcgtt gacttcgatc acttctaaat gtgtcatatt ttttacttct ttgccgatta
     3361 cttcttgcat ttcttcaaag attttttcga tatctttgcc atattccaca atgacatcca
     3421 tatcaactgc tacttgtttt ttaccgactt ctgtttcgat cccagccgtt acattatctg
     3481 tattcacaag ttttcctgcc acattagaga agaaaccacc gtttgcagat aataaaccgt
     3541 ctacttgttc aattgcgatt ccgatgattt tttgcacaac tttatcttca taattcagct
     3601 caccgcgcat tgaatcttcc tgttcagaat catgctttcc ttggttattt gtatgatcag
     3661 aaccaagttt tccttgtccg tttgtgtggt cagaactaag tttttcttgt gctttcgcat
     3721 ggtcagaagg atgtttttgc tcttccacag gtttagaagg atcgattgca tcatgttgtt
     3781 ctggaacttt agattctgga gttcctggat gatgaggtgc atgcttttct gcatcatgtt
     3841 tcttctcttc tactccttgt tgaacgttag ggactactgg atctggatgt gcagatactg
     3901 gtgctgtttt gttcttttca tcgttcacac catttgattg gtttggtgtc gttgggtctg
     3961 gatgtgcaga cactggtttt tggttgttca ttttattgtt attatttttg ttattgttat
     4021 tcatggatgt ttcctcctaa gatttaaaat agtgatctaa gattttcgtt tgtttcagat
     4081 aaaaaccgat agcgacgccg atcgctgcca tgatcaagat caataaggtc ttgaaaaagc
     4141 ccacggtgat ccataaaacg gctaatatca atccaagtac cccaaagatg atagggagct
     4201 tgtatgtcga aaatagttct ttcatttttg gtccccccct attctactcg tttgcggtca
     4261 ttgcttcgtt tagctggttc ttcaaagcct gtgtatttca ccgatacttt cactggctct
     4321 tttgttccca atatgtgttg tacttcattt tcgatttctt tcatcaatgt tcctgtttta
     4381 ccaatgagtg ctgaagttcg tttcaactcc ccttttacat tgacggcgat cttgtttttc
     4441 gttgctttga catttacttt tggtgaatgg atgaattcat cttcatgcaa gtgagaacga
     4501 accattcctt caattgcttt tttatccaac gtcaactccc catcaccatg tttcagtaga
     4561 aagtttccga ttgtttttgg ataaaacagg aaaacaagta acgtgataat tgtcaaaata
     4621 gcaaatgcaa cggcaagcca aaatacatat tgttgcacgt atgaattagt gatggaaaag
     4681 aatcgaaact tctctagctg aaaaggcaat ggataggttg cacttaatag tatcgcaaac
     4741 aaaagcacag atagcaaaag taatgttccg atcactccga tcgtttttac acctttattc
     4801 attttcgcac ctcctcatag gggtgaaacg atcaacttct tataagttga tcgcttctcc
     4861 accagttact ccgtaaattt gggctgtaac ataacttgct ttattcgatg ctaagaaaac
     4921 ataaactggt gctaattctc ctggctgacc tgcacgttct agtaaacttt gctgaccaaa
     4981 ttcagggatc gaatcagaag gttgtccttc gtctagttgt aatggtgtcc agattggacc
     5041 aggtgctaca ccatttacac ggattccttt aggtgcaagc tgttttgcta aaccgatcgt
     5101 aaagttagcg attgaagctt ttgttgctgc gtaatctaat aaatgttcgc ttggattgaa
     5161 tgcttgaaca gaagttgttg ttacgattgc tcctcctgct gggatatgcg gaacagcttc
     5221 tttcactaaa gcaaacatag cgatgatgtt tatcataaat gtgtctttga cttgctcaag
     5281 tggtaactca gcaatagact gacaagaaat ttgctgtcct gcgtttagta ccatcgtatc
     5341 tagcccgcca agttcactca cggctttatc tatgatttct ttaggtgctt gttcgtcacg
     5401 aagatcaaaa ggtagtaaga caatcttacg tcctgcaact ttcacgtatt ttgctacttc
     5461 ctctgcatct ttttcttctc ctgggaagaa ttgaagagcg atatctgccc cttctctagc
     5521 aaatgcaatc gctgctgcac gaccgatccc tgaatctcca ccagtgatta gtacacggcg
     5581 gttttctagt tgattattgc cttcatagga ttcttctcca caatcaggaa caggaatcat
     5641 attctgctgt aaagctggtg tatcctgatc ttgtttagga aatttctccg tatggtacaa
     5701 gtttcgcggg tcgattaatt ttggttctgt cattgctgta ttcctcctag tttttaaatt
     5761 gtattgccaa aacaaatttc tttgtttgat acctgtttta aatagattct ttaatttgta
     5821 taatctttcc ggtataaatg gtaacctaaa actactgctg ctatcaaaga gccaaagact
     5881 acgagtataa agcctagagc agaactttta cccggtaatc ctcctgtatt cattccccaa
     5941 atccctgcga acaacgccgg aacggaaatg attaatgcag ctgaatctag atatttcatg
     6001 atatgattta gattattgtc catcatcccg ttgaatagat caccaatact ctctaataaa
     6061 tctcgataga tctcgatcat tttttctgtt tgtcgctgtc tcaaatggac atcatagagt
     6121 agctgttcat cgtctaaacg tttgatgaaa gtttcagaat tccataattg atccattgtt
     6181 tcccgttgat ctcttaaggt atgatcgata tatacgatgt ctctttcaag atctgcctgt
     6241 ttatacagtt cttcattttc cgttgtttta cgagctgctt tatccaaagc gtcaattcgc
     6301 tttttcatct ctcttagttc tttcacgtaa tgggtgtaaa tatctaataa tgtatacgtg
     6361 atgatctttt caaacgagtt taaatgattt ccatgctttg tcagcagccg atccacaaat
     6421 tcggtttttc tatcgataca agtaatcaag agattatcgg aaagtacaaa agatattggc
     6481 gttaattttt tttcgatacg attatctgac tgatctagat taatcactac caaagaaaat
     6541 ggatgctcta gtttcgtctc ataaaggcgc tccatccgag aaacttcttc cggatattcg
     6601 gttcctacga aaatatcatc aggaagctcg aattcttcga ttgcttgctc aatctcttcg
     6661 ggctttgcac tatcaagtac gagccaatta tatttttttt catctgtttc tattacattc
     6721 ttttcttcat ccacaaagta gtatctcaat gtatacctcc tttttggact ttctcgaaac
     6781 tattagctga agaagcagtt ctttaatttg atattataat cgagtactgc gatttcattt
     6841 tctaatgaaa agctgtcaag ctgtttgttg aagtccatgt tcaatcgttt accgaaataa
     6901 ttttgctcta atttagatgt atagatgtcc aataatggat gctcgatttt agtcgcatat
     6961 tctccaaatt ccgaaacaaa aggaatgatt tgaaaaaagc tgccttttgc aaaagcacct
     7021 ttgtccctta gaaatggatc ggaatcattg ataagcgcga gtgcgatttt tgtattttcc
     7081 ccaacctttt caattaacgt ctctactgca tttttagaca ttgtaatttc cattcctact
     7141 ccccctcttc agttgttgtc ttctattatt taacaactac atctgttttt ggttgaactt
     7201 ttgcatattt tggatattta gggaatttag ctacacaacg gaaagccgtc atccctgcat
     7261 atttttcgta atatttcttc gttggccctt caaaatcctt gctccacggt ttcacatgtc
     7321 ctgaaaaatg gataatgtaa ggattgttgc gagtttcttc gtattcacgt tcacctgctg
     7381 ctgttggatg tttttttgct tttgccatga tatagccttg tgcattccaa cgcggatgaa
     7441 gtggtaacca acggtcatgt aagatagcat ttaatgcatc ttggtcatgg aatcgtaatt
     7501 tttctggatt atgttcgatg aaatctaata ctttttgcgt aatattttca tctaaccatt
     7561 ttttcacatt gatcagcatc aaacctgagt tgaaataacg cattgattta gctgaaattt
     7621 tcattttttc cagtcgttga tggaacccag cgtcttcaac agctgctacg attgaatcac
     7681 cgaagtcaag acgccataat ttagagatat cttgtaaagc gatcatgtcg caatccatat
     7741 ataagatacg ttcaacttct gtgccgcgga acaattccgg aatcgcaata cgataataag
     7801 ctgtttctgg aatacgatcg ctgattacca catttgtaaa gaattcttta ttgattttca
     7861 agaattccac atctgagttc attcgtgcgt ttttcactga gaagcgtaaa agctgtttac
     7921 tttcaaaatc gatatcatcg tcaatcacat agaaccgaac aaatttagac gggttgcaat
     7981 tatctaatac tgagacaaat aatgcagcta aatgtggtac gaattttgtg ttacaacttg
     8041 cgactactgc tatttctttt ttattcattg atctcgccta ctttcgttag agtactgtgt
     8101 gctaattttt ttaagtataa attggtatac ggatgatctt tcaacgtatt ccaaggttta
     8161 tcatgtcctg taaagtgaac gatcgaaggt ttttcatttc cttctttata ctgacgttca
     8221 tatttttcat ttggtgctgg atgacgttca aaaatcagcg aagtctgcat gttccatttt
     8281 ggatgaagtt gttcccaatc ttcataaagt acagcattca aagcatcttg gtcgtgatag
     8341 atgattcgat cgccattttc actgaggtaa tggatagttt tttctgtaat ttctttttta
     8401 ttccattgat caatgtcaat caccatcact cctgaattga agtacaagtc atcggaatcg
     8461 attcctaatc tttccaaagc tttcacttgg cctggatcga taatagcgcc gattgttttt
     8521 ccatttaacg gctcatcata tagttttacg atatcgtcta gtactaacac atctgaatct
     8581 aagtaaagga ctttcttata atcctcttta gctaataagt ttggtaaaga aattcttaag
     8641 taagcggtag ttgtgatatg gtcactgact aggaagtctt cgtagatatc tttttccact
     8701 gtcaggaatt ggatacttgc attacttgaa tatttattta ccgtttcttc caatccttct
     8761 ttactatatt ctgatagacc atcgtcaatc acataaaatt ttatgcgtct tgttttattg
     8821 caattttcta atgcagttgc gatcatcacg ctcaagtaag gagcataatt ttcgtctgaa
     8881 gcagttacca caggaactac gccgtatctc ttctccatca aaatcactcc tttttctaat
     8941 ctttttctaa cctgttctac atctagaata ttcctcattt ggttttaaag caaaatatat
     9001 gctttgtttt cattgaatat tttaaaattt ttttatcaca aaacgcatcg gtaagcgcta
     9061 actattcgtt tttcatggct ttttattcaa
//
LOCUS       DADQCX010000100         8896 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.102, whole genome shotgun sequence.
ACCESSION   DADQCX010000100 DADQCX010000000
VERSION     DADQCX010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.102"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            151..1211
                     /locus_tag="J8R83_002349"
                     /pseudo
     CDS             151..1211
                     /locus_tag="J8R83_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
     gene            1214..2110
                     /gene="murQ"
                     /locus_tag="J8R83_002350"
     CDS             1214..2110
                     /gene="murQ"
                     /locus_tag="J8R83_002350"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAZ9575465.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            2124..4106
                     /locus_tag="J8R83_002351"
     CDS             2124..4106
                     /locus_tag="J8R83_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9575466.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(4171..4617)
                     /gene="nrdI"
                     /locus_tag="J8R83_002352"
     CDS             complement(4171..4617)
                     /gene="nrdI"
                     /locus_tag="J8R83_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAZ9575467.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            4828..6252
                     /locus_tag="J8R83_002353"
     CDS             4828..6252
                     /locus_tag="J8R83_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9575468.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(6433..7206)
                     /locus_tag="J8R83_002354"
     CDS             complement(6433..7206)
                     /locus_tag="J8R83_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9575469.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(7203..8108)
                     /locus_tag="J8R83_002355"
     CDS             complement(7203..8108)
                     /locus_tag="J8R83_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9575470.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(8262..8582)
                     /locus_tag="J8R83_002356"
     CDS             complement(8262..8582)
                     /locus_tag="J8R83_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAZ9575471.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         2798 a         1589 c         1884 g         2625 t
ORIGIN      
        1 ttttttaggt tatgacaatt cttttgataa tataaactca acctttagaa atgaaattta
       61 attattttaa taaaagtatt gaaattttgt ttctttagat atatactcta gtcatagaaa
      121 tgaagacgga tacagaaaaa gagggataat atgtttggct tttcaatatt tatgaacgat
      181 tctttgtcag aagagaagaa acagtatatc cgccaaatgg catccaatgg ctttgtcggt
      241 attttcactt ccatgcatat accagaagat gatgtttcgg catatcaaaa gcgattgatc
      301 gaactaggaa gcgaagcgaa aaagaataaa ctagaattga tggtcgatat ttcaggagag
      361 gcattggaac gagcgggttt ttcattagaa gatctaacgc ctttgaaagc aattggtgta
      421 acaggtttaa gaatggatta tcatatttcc aatcagcaga ttgccgactg gtcacatcaa
      481 ttgaaaatca gtttgaatgc tagcacgatc acgcctaaag atatcgatga attgaaagaa
      541 gcagaagctg atttctcaca gattgaagct tggcataatt attatccacg tcccgaaaca
      601 gggctggaca aagaatggta tcagaaaaaa atcaatggct caaaattcaa ggtctccttg
      661 tccaaggttt tgtaccagga gatacagagt tgagaggccc actatatcaa ggattgccaa
      721 ctttggaaga acatcgaggg atccatcctc ttgcaggcgc tctagatcta ttagcaagta
      781 acacggatat tgtttacatc ggagatgcag gtctgtcaga aaacgttcag gagcaatttg
      841 cttctttcca aaaagaacag acagtcttgc tccatacgga acctgtagat gaagaatttt
      901 acgaatatat attagggaag catacgaatc ggcaagacga tgcaagagat gtcatacgaa
      961 gcgtagatgc acgttttcga gagattccgc ctatcccagc aagaaataca gctacgcgta
     1021 tgaaagggtc tattacttta gataacgaaa agtatttgcg ctatatgggt gagatccaat
     1081 taaccaaata tgatttgcca gcggatgaaa aagtgaatgt agtagctaaa gttatcaaag
     1141 aagagctacc attgatcaac caaatcaaag ctggtatgaa ctatcaattt ataagaaaag
     1201 aaggaagata aaaatgagca aaatcaattt agagaaccta acaacggaac gcagaaacca
     1261 agaaactttt ggattagatg agatgagtat ttctcaagcc gttcaactaa tgaacaaaga
     1321 agatcagaaa gtggccgctg cggttgaaaa agaactgaca agtatcgaac cagtgattgc
     1381 taacacgatt gagtccttta aaaaaggtgg acgtctgatt tatatgggag ccggaacaag
     1441 tggaagacta ggtgtgttag atgctgctga atgcgtaccg acattcggtg tagaaccgga
     1501 aatggtcata ggtctaattg ctggtggaga agaagcaatg actgtagctg tcgaaggggc
     1561 cgaagattct tatgagctag ggcaagaaga tctaatcaag ctgaatttga caaaaaatga
     1621 tatagttatt ggtatcgcag ctagcggtcg tacaccatat gtgatcggtg gattagatta
     1681 cgcaaaatcg atcggtgctg tcacaggaac gatttcttgc aataaacaag ccgaaatcag
     1741 taaacacgcg gatttcccaa tcgaagtcga tgcaggtcca gaatttttga caggctctac
     1801 tcgattgaag tcaggaacag cacaaaaact tatcttgaat atgatttcta ctatcagtat
     1861 gattggtata ggtaaagtat tcaataactt gatggtcgat gtcaaaccaa caaatgaaaa
     1921 actaatcgaa cgctcaaaac gaatcatcat gcaagcgaca gaagctgatt acgaaacagc
     1981 tgaaaagtac tttgaagaag cagatcaaaa tgttaagctg gctatcgtca tgattttgac
     2041 aaatagtgat aaagaggaag ctcaagcaaa attagctgaa gcaaacggat ttgtaaaagg
     2101 gaccttatga gggggaaaag accatggcaa aaaacgaact gactttggaa gaactggcaa
     2161 aacaaattta taaaggggca ggcggcatgg gcaatgtaga aagcattgtc cactgcatga
     2221 ctcgtgtgcg tatgaagatc atcaatgatg atcttgtaaa tgtctctgaa ttaaaagcga
     2281 ttccaggagt gcttggtgta gtagaagatg aacagcttca agtcatcatc ggacctggga
     2341 aagtgaacaa agtagcacag caaatggttg atttggcagg cgtgaaatta ggagaaaaac
     2401 tttcttctgt aagtacagct acagcaaatt catcagcatc tggaaaagac cgtgtaaacg
     2461 aacgggcaca agaaatgaaa gcggcacaaa aatcgaaaca aaaaccatct aaaatcaaat
     2521 cggtattaaa agacatttct aatatctttg tgccaatgat tcctgcattt gtcggtactg
     2581 ggatcgtggc agggattgcc gcagttttag caaacttagt cacagccgga acacttgatg
     2641 cagcaacatg gcaacaatat atcgatgtga tgaacatctt gaaaaacggg atgtttagct
     2701 acctagttat ctatacaggt atcaatgctg cacaagtttt tggtgcaaca ccaactcttg
     2761 gtggagttat cggggccgtt gtgatgctga cagggatgaa tccggaagca ccactgaaaa
     2821 acttatttac tggtgaagct cttgcagctg gacaaggtgg gatcctaggt gtcatcttcg
     2881 ctgtttggct attgtcaatc gttgagaaaa aactgcataa agtagtacct gatgcggtag
     2941 atatcatcgt tacaccaact ctttcattga ttgccatcgg tctgattgaa attttcttca
     3001 tcatgccttt agcaggtttc atttctgatg gcatggtcgg tgggatcaac tgggtacttg
     3061 gcgttggtgg agcatttgcc ggcttcgttc taggcacatt attcttgccg atggttatgt
     3121 tcggactgca tcaaattttg actccaatcc atgtgcaaat gattgatgaa actggtcgta
     3181 cgctattgct tccaattctt gcgatggctg gtgcaggaca agtgggtgca gcattggcat
     3241 tatggattcg ctgcaaaaaa gataaagaat taacagaaat gatcaaagga gctttaccag
     3301 tcgggatcct aggaatcggc gaaccattga tttacggagt aacattacct ctaggacgcc
     3361 catttattac tgcttgtatc ggtggaggta tcggcggggc agtgatcgga atgatcggaa
     3421 atgtcggggc tatcgctatt ggaccttcag gagccgcttt gatcccattg atctctgacg
     3481 gtaaatggtt aggctacatc cttggattat tggcagctta tgctggtggc ttcgttgcta
     3541 cattcttctt cggtattcct aaagaccgtt tagaaaaaga agaattagcg actgaaacag
     3601 ccacagtaaa tgaagtgcct gaaaaagtag tacctcaaac ttcagctgaa agtgtgacta
     3661 tcctctcatc agttgctgac ggaacagttg tttctttaga taaagcaagt gatccagttt
     3721 ttgcacaaaa gatgatgggt gaaggctact ttgtagaacc agaaaacgga catatctatt
     3781 ctccagttac tggggtagtc agctctgtct tcccaacgaa acacgctatt gggatcacaa
     3841 cgccaaatgg tttagaaatc ttgcttcata tgggaatcaa cacagttgac ttaggcggta
     3901 cgccatttga tgtgaaagta acagaagggc agcaagtgac acctgatacg cttgtagcag
     3961 aagctgactt agaagcgatc aaagcagcag gcaaagaaac atccatgatc gtcttggtaa
     4021 ccaatatgga tcgtgtaaaa aactttgtct tggaaaaaac aggtaaagca aaagcaaaag
     4081 cacctgtgat ggatgtcaaa gcttaatatg atagaaacaa tagaaacgaa agaagaaact
     4141 gaaatctatt tttcagcttc ttctttttta ttatttattg ttttctgcta aaatctgata
     4201 aattcgtgtc acatcagatg gtgttccccg taattcataa tctgccaaga aaggaaagcc
     4261 aaatgtttgt gcatattgtt tggctgttag acaatactga ttattgaagt ttttatttcc
     4321 gctaccgact acaccaagac aaagtttatg attgtcttca tgttccagat attcacgcat
     4381 cgtttcggtc aagatttctg tatcaccgtt atctaaacca tttccgccgt ctaaataagt
     4441 aggaacgaaa gtaaaaaatg gttctgtttc tttcgtaaaa tcactatttt catggatttc
     4501 ttttaaagta acttcaggat tgacaggatc ttctgcatgc attttttcag catattctgc
     4561 tagatgtttg gcaaaggcac gcgtatttcc tgaaatcgat atatataaaa tgttcatgga
     4621 tcatcctcca attctttcct tttagtatag catctttttt aagttttttg gtggtgtaat
     4681 ttggaaaggg actaggcgct ttgcttgtat aatgagaaaa aagccggtag aattatattt
     4741 ctattaaagt ttttattaat taagtaaaaa taaaaaaggt ttgttatact ttttgataaa
     4801 agcggtttta ttttggagga tgcttacatg gatacagagc aacagaaaaa aggaattggt
     4861 ttaattccac ttgctgcctt agtaattggt tcagcgattg gaggtggcgt atttggtatt
     4921 atgacggaca tctccggatc ggctggcggc ccagctattt tcagttgggt actcgtagga
     4981 acagcaatgt tgatgctctc cttgtcgatc aataatatca ataaaaaacg tccagattta
     5041 aaaggcggga tctttagtta cgcagaagaa ggttttggcc gtttcgctgg ttttatcagc
     5101 ggttggggtt actggctcac atgctggtta ggcaacgtag cttttgcaac attgttgatg
     5161 agcgcattag gatatttctt cccagtattt gaaggtgggc aaaatctggc atcgatcgtg
     5221 atgagtacag tctttttatg gggatatgca tggctagtga atcggggagt cgaaaatgct
     5281 agtttcgtca atgctatcgt cacattctgt aaattagtgc cattattttt atttattgta
     5341 gtagctatca gcacgttttc gatccaacaa ttcattgata acttttctag cgacattata
     5401 ttgaatgcga atggacagcc gatcccgttt tccagtcaag tattgagttg catcatggtg
     5461 atgctttggg tatttgttgg tattgaagga gcctctgtcg taggttcacg agcaaaaaaa
     5521 caatcagatg ttgggaaagc aacgattcta gggatattcg gcttgattat tatttacgtc
     5581 ttggtttcca tgcttccata tgggacaatg acgatgaatc agctgcaaac gatcaaggcg
     5641 cagcctgcta tgggctatgt gtttgaaatg atggttggta aatggggagc agtcgtgatc
     5701 aacggcggtt tgatcatttc tttagttggt gtttggctct catggacgat cttaccgatt
     5761 gaaacaatgg gaaacatggc tgaagacgga cttttgccta aagcatgggg aaaactcaac
     5821 aaaaatgggg caccaactta tgctatcgta ttgacgacgt tatgtacgaa tgtcttttta
     5881 ctttcattat tattcactga cagtgcttat aactttgctt acacacttgg tacagcagct
     5941 attttcttca cgtggctttt cttaggattg taccaaatga aactttctta tcagcggaaa
     6001 gaatgggtcc aatttttagt agggctttta gcaagtgcct ttcaagtatg ggctatgcta
     6061 gtcgtagcct ttaatgaagt aatgcttgtt cttgttcttt tcttgccagg catttatttt
     6121 tacctcaaag cacgtaagga gcaaaacgag cctgtacaac atatccactt agataagatt
     6181 ttacttatag gtgtgacgat ggtcggagtg attgcaatgg ttttatttgc cactgggatg
     6241 cttcacgtat agaagtataa aagaagtata aagagaggtt gtgagcctgt cgtttattca
     6301 aaaacatact aggaaaggag ctgtgacaca aatgttgtca cagctccttt ttcagaataa
     6361 acggtgttta agagacagcc aatcggcaat aaggctgaac gtctctttca cagcctcttt
     6421 tttgatgagt catcatacat tttttcgctt aaatacgaga tatcctaatg ctaagaacaa
     6481 aacgatgtaa gctaaattac cgaatagcat ttgattagta gaaagatgag tcaattgctt
     6541 catgatctct tcgtttccaa tttggttttg cagattcaac atactgatcg gattccattt
     6601 gatccactcc catttttgga tgagtgcaat aaggatacca gatatgattg acgaagcaaa
     6661 ataaaagacg attcctgctg agatggatgc gccggaacta ttgataaagc aagcaatcat
     6721 caacactaaa cttaaaatca gccataaacc gatataacta cccaaagtat aagtgaacaa
     6781 gctttggatc agtgtttgac cagtagaaac cttctccgtg aaggaaatcg aagggaaaag
     6841 aatcagtttc atcaacacag tgacaataat agctaaaagg tataaataaa cagaataaat
     6901 aactaatgtg atccatttgc ttactaatat ttctcctcga gaatactttc gataaaggag
     6961 atttttcaat gtaccatatt gtgcttccat cgaaatgatc gtgcttgcag ctgcaatcat
     7021 gataaagaca atccaagatg tggcactaaa aagctgagca gtcatttcaa ctggatcaat
     7081 gatcgtcgtg tattttttgg ctagaagtgc tgttcctatg agcaaaacaa ctaatagaac
     7141 agataaaaca gcagttgact ttttcttgat caatttaaat aattcttgtt ttacaagcaa
     7201 tgtcattttt cttcttcccc ctttactgaa tccagaattt ccaatagaga agattccaaa
     7261 tcattcgtca gatgctggac gtctgtcaca tggatatttt gtgcagacaa tagctggatc
     7321 acggttccta ataattcttc gttttctttt aaaagcttga ttttatcagg atcttccaaa
     7381 gtatatccag cttctgtcaa gatcgttcga gcagctagat catttgttgt agagataacg
     7441 atgaaatctt gcgctgtttg gttcaattca gccattgtac attgtttgat gatctttcct
     7501 tgattgatca ggatcagctc atcgaccatt ttttcaagct cgctgagtaa gtgactggag
     7561 atcaagaaag aggtgccctg agtagccaag tcggtaatga tttttcgcac atctcttgtt
     7621 gcttgtggat ccaaaccgtt catcggctca tctaaaataa cgatagacgg atggttcagt
     7681 aaggcaagag caattcccaa tttttgtttc attcccaacg agtaggattt cgcttttttg
     7741 tgaatgtact tttccatctt gagctgattc acgatagtgt cgatagcaga tacatcgttg
     7801 gtttcagaga ataacttcag atgatcatag cctgttaaga atggatagat acccgggtat
     7861 tcgatcaatg ctcctacttg ttccaaccct ttatgactag agggagaaat ctcattttca
     7921 ccaatacaga ttgttccatc tgagtaatgg atcagtccta aaatagcttt catgatcgtt
     7981 gtttttccag cgccattagg acctactaat ccaacgattt tgccagggga taagctaaaa
     8041 ctgacatcgc tgagggcttg tttgtgacca aagttcttgg ataattcttg gaccgaaaga
     8101 cttttcaaaa atattcactc cttttctata gatagtacaa gcatacacct gatgagtgga
     8161 gaagtcgcta ggtcattgga cttatttctt attttttcat aaaaaaattg aatattaaat
     8221 aaaaaggctt attttttctg atcagtactt attccaagtg tctagtggcc gctagtaatc
     8281 ttgatgccaa tgatactgat gagtagcatc cccacaaaga accaagtgga aagattcagc
     8341 ttatcatgaa acaagaccac accaattatg accgaaccaa ctgcgccaat ccctgtccag
     8401 ataggataag agagactcat cggcaaactt ttgattgcct ttgacaaaaa gtaaaaacta
     8461 gcaatcatgc caatcactgt gtaaaaagaa taattgattt tagaaaaacc atcactccat
     8521 ttcatcatcg ttgaccagaa tacttccaaa attcctgcta tgattaattc catccatgcc
     8581 atacttacat tcctccttaa ctataaaaaa atacacaaaa agaggaaaat catcccttca
     8641 aagacctaat ggaatgatca tcctctttat cctacccggt ggcagattgt atatcttttt
     8701 ctgtagtata gcacacctat ccagatatcg gcaatctcat actttttagt aaagtgtacc
     8761 aagcactgac ggatatatcg ttagcggaaa agaagatgaa tgctttgcaa tttcatagaa
     8821 agaagttgtt atttattaat catttaaaaa aaacagtaac tagaccttat ttctatatat
     8881 tatcgggcaa taaatt
//
LOCUS       DADQCX010000101         8817 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.103, whole genome shotgun sequence.
ACCESSION   DADQCX010000101 DADQCX010000000
VERSION     DADQCX010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.103"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..1086
                     /locus_tag="J8R83_002357"
     CDS             4..1086
                     /locus_tag="J8R83_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9575472.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1304..2446)
                     /locus_tag="J8R83_002358"
     CDS             complement(1304..2446)
                     /locus_tag="J8R83_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9575473.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2451..2636)
                     /locus_tag="J8R83_002359"
     CDS             complement(2451..2636)
                     /locus_tag="J8R83_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAZ9575474.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2990..3235)
                     /locus_tag="J8R83_002360"
     CDS             complement(2990..3235)
                     /locus_tag="J8R83_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575475.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3229..3630)
                     /locus_tag="J8R83_002361"
     CDS             complement(3229..3630)
                     /locus_tag="J8R83_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9575476.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3817..5625)
                     /gene="uidA"
                     /locus_tag="J8R83_002362"
     CDS             complement(3817..5625)
                     /gene="uidA"
                     /locus_tag="J8R83_002362"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAZ9575477.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5648..7414)
                     /locus_tag="J8R83_002363"
     CDS             complement(5648..7414)
                     /locus_tag="J8R83_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAZ9575478.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7427..8221)
                     /locus_tag="J8R83_002364"
     CDS             complement(7427..8221)
                     /locus_tag="J8R83_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAZ9575479.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8231..>8817)
                     /locus_tag="J8R83_002365"
     CDS             complement(8231..>8817)
                     /locus_tag="J8R83_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9575480.1"
                     /translation="FPDYYNDAQGIVLMNFINPILVLIVVSPLTLFLSKKYGKKELAS
                     VGMFFSAIVYLILFLIKASNMYVFLILSSVGYMGLGVFNTVIWANITDVIDDQEVKSD
                     QREDGTVYAVYSFARKIGQALAGGVGGWTLSIIGYDSLANVQTGDVLEKLYNASTLIP
                     SICFLIVGLILFFLYPLSKDKVLENCELLKQKHK"
BASE COUNT         2861 a         1690 c         1174 g         3092 t
ORIGIN      
        1 gatatcaatg atgatggctc aagaaaaaaa gtggagaaag ttggcggaga cacccgacca
       61 gaggccgaag ctgctttacg aaaagtttta tcagatattg acgaaacagg acaatacttt
      121 ttaggtacgg atactcgagt aaaacaatac cttgattttt ggatggagga atacgttaaa
      181 ctaaatctaa aatacaatac ctatgaaaac taccgattta ccatcaaaaa tcatataaac
      241 ggttatttag gaaagaaaaa acttacggat ctctcccctg ctcttttaca aaatttcatc
      301 aatgctgaat ttaaaaaggg ttactcgaag aaaacaatga ctattactca ctctgtcctt
      361 aagaatgcgc tgaatatggc ggtttatcct tggggattaa tcaagcaaaa tcctatgctg
      421 tatgtaaaaa taccaaaata tgaagcacga ccaacgacta aaaaagatct aaaaatcatt
      481 tctcttgagg actttgatca tatgctagaa attactcctg aaggacatcc tttctatatt
      541 cctttgaata ttggatttta tacgggaatg cgcgttggcg aagtttgtgg tctgacgtgg
      601 gatgatgtcg atttttcaaa tggaacaatt actgtagaga aacaaatggt aaagaatgac
      661 ggcgcatggg tatatggtac gccaaagaca agcagttcca atcgaacgat ttttattgga
      721 caaaccttgc tagcaattct gaaaaaacat aagaaacaac aattagaaaa tcgaatgaag
      781 tatggaaagc tctacattga ttcaaatgca gtatgtacga aggaagacgg tgagctagtt
      841 acgccaagtg tagtgaaatg gaatactagg aggatatcga atgcactctc cctctctttt
      901 aacttccatt ctctcagaca tactcatgct acacttcttc tcgaaaatgg cgcaaaaatg
      961 aaagaaatct ctgaacgatt gggccacagc agaatttcaa ttacgatgga tacttactcg
     1021 catgtaacag ataagatgag aaatgaaacg gtcgatatca tggaaaatct tagaaagaat
     1081 tcttgatttt tgccaccgaa aaaaaccacc ggtggcaaac cggtggcaaa tccatgtaaa
     1141 catggtttat tttttacact gttttcaaac aaacccttgc tatttcttcg gttcgtcctc
     1201 gtccattttc gataccgaca gctagcttat aacccaaggt atatcaacat aaaaaaataa
     1261 aaataggcta tgacagcagc gtgacagcaa aaaagatgga aagttaaata tcaaacctcg
     1321 taatttcatt tgcgagtgct tgatttgttt ctggatataa gtgtccatat ttgtccaaag
     1381 tagttttaat agaggcatga cctagacgct tagatattgc atagatattt ttattatgtt
     1441 caattaaaaa ggcaacatgc gagtgtctta atccatgcat atgaattggt tttactcctg
     1501 caatttcagc tagttttttt attctgctta aaatagttct tggagatggc ggtaatccat
     1561 caaaagaaaa aaccaattct atatttttcc caattgattg ttgagttttt ttccatgttt
     1621 ttaaatcttc aacggtttgt ctgtctaacg aaattatccg aatacttgat gtattttttg
     1681 tttcagcaaa ttcataatct tgtcttgtac ggatgtaaat tgacttattt acgctacatc
     1741 tgccatttat taagtcaaag tctttccatt gtaacgctaa gagctcctca ctccttacac
     1801 ctgtaacaaa aataaaacgc atcaaacgtt tataaaattc ttcataaaaa tccccgtgat
     1861 aaacactatt atatactttc ttaaattcat caactgtcca aaattctact tgaggacgct
     1921 gagtttttat tttacctata gtatctacag gattttcttc aataatttca agtacaattg
     1981 cccttttaaa aactactctc aacttattga atatctgttt aatataattt ggtgataatg
     2041 gttgctcaat gccctttttt acaacatgga ttttcgataa aaactgttga aattcctgta
     2101 tatgaattgg tcgaatcttt acaacctgca tttctccaaa aaaatccaat gcacgttgta
     2161 aaatatgatc tgttttcata tatgtttttt ctacagttcc caacttatac caaggaaaaa
     2221 aatactctcg ataaaaatca tgaaacgtta ttccttgcag ataaattcct tgtgaatcag
     2281 aaaaactttg ttttaactct tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc
     2341 ttctggtcac ttgaattctt tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc
     2401 aagtgcctct ttttctgtct ttataaacat tcgcaatttt cctcatttta ctattcctcc
     2461 caagaaatat ggagaacttc ttctaaaatt gaaataggaa ttctttttat ttttgaatta
     2521 cgataaaaaa agtatccttt ctcaactaaa agttctttac attccttgaa gattttatta
     2581 gcatagtact gagaaaaacc tagattaatc aaatcttttc gagtagctgt tttcattata
     2641 gcaccttcct tacttttttt catttatttc tatcagctgc ttttgtcaaa agcacatagg
     2701 aatttcacct ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta
     2761 aatcatcgct ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac
     2821 agcaagaaat catggcgcaa ctaaaatatg ctccttaaag tgttaacgta ctgatagaat
     2881 ctatttaatt ttcaatgaac aataggtttt ctacctaaaa gaatctacta attccttaac
     2941 tattagaaga ttcttttaaa cagaaaaagt ggaaagggga tttttttaat tagttaattt
     3001 taaattttaa gatcgcttct attaatttaa tttctagctg acttatcata tattcatcta
     3061 cataggtaac gaattgacct acctcgttaa atccatttgt caaacataac ttagccatat
     3121 aagaatgata atgtttgagt atcatcttga tcgaaattgg atctccttct agagcagata
     3181 agataatgga tagtggaact aataggtact gccgcttttt agatttatct accataggtc
     3241 ataccccatt ttcaattgtt caactgcctt ctttcgttga taccagatac cacttgtgct
     3301 catattgaga attttaccga tttcagcatc attaaaacct gcaaaataat aaagtaggat
     3361 aatctttctt cttatctccg ataactgatc aattgctgct gataactttt gatctgaaat
     3421 taatatttcc attccaaata agaaatagac atcttgttca tcaaaatgag tttgggaata
     3481 cctgccttca tttgaatctg ccaatggttc ctcattatcc tttatgttag cgtttcgttt
     3541 tcgaatagac ttagcttcgt ttcgtaatac ttttttacag taggcatcaa attggtgttg
     3601 tatagatatg tcattgtaat gttgttgcat gataatatgc tcctttttcc ccctttccac
     3661 taatacaaca atcagaaagc cccttttttt cgaaaaaact agaaaaaaaa cataaaaata
     3721 tttatcattc tttaaacaga aaatctttct ataaaaaaca aaaaaaaacg attaggctag
     3781 gctaatcgtt ttttgaacat tcttaaaaaa tccaaattat tttttataac tgaaattggg
     3841 tattgatgac catcgtttct gtagatagta agcaatcatt ttaggttttc tatctctagt
     3901 aaagattcct ttcttatttc cttgcactct taaaatccct tgacttgttg caaaatctgc
     3961 aaaattccac acttgttcac caacaaaatt ttcacatgta tctattactt cgtgatttgc
     4021 ttcgtaataa gccacttgat actcttctgt aaacattgtt ggtactgtat catgaaatcc
     4081 agctactgta tctgctccat attctgtaaa cattattggc gtatcaggac atctttccat
     4141 ccatccatct agctcttttt tcaacagata ttttgcatgt gccagatccc ctcccgaaac
     4201 ataccaacca taataacgat ttaaacataa aacatcgaca atatctccta ccttacaaac
     4261 atctggcgtt gattttagat aagtaacgat tgttacaggt cttttctgcg gatcaagttc
     4321 tttagttaat tcaactaaag gttcaaaata ttctttagca ccttcggaat ccgaatctgg
     4381 ttcatttgca atagaccaca ttacaacact tgggtggttc ttgtcgcgtt ctatcaattc
     4441 cttgatcacc gttttatgag aattttctgt tcgtatctct ttccacgtat tatgtttttc
     4501 cacattatca tctaataaag tggccatgaa atttaaatgt aaccctactg caggtacttc
     4561 atcaataact acaatacctt ctcgatctgc taatcgcata atttcttctg agtaaggata
     4621 atgtgatgtt ctaaaagaat tagcacctat ccatttcatt aaattaaaat ctttaatatt
     4681 tacagcctca ttcaaaccac gtccattaac atacgaatcc tcatgcttac caaatccttt
     4741 aaaataaaaa ggtttattat taatcaaaaa tttgccattg gtaacctgaa cactgcgaat
     4801 accaaattct tctgtatagg tatcgatcac tttattatca tcaattaaac taattttcat
     4861 actatataaa taagcgtcta gaggttccca aaaaattgga ttcttaagct gaatcattcc
     4921 tttctttcct tcagcttcag ctacaagttg agcctcttcg tcatatatcg ctattaagat
     4981 ttttccggtc cattctgtat cgatattgaa ttctacactt gcatccaaat cagttattct
     5041 tgtattaata gtaatatcac ttatatagtc tttcggagtt gtatataact taacaggtct
     5101 atgaatacct gcataattga agaaatcaaa attaactaag ttttcctttt ttatatcccc
     5161 attttcctgt actgtttcct tcataatccc cacaggtaaa gtactatcgt caataatatt
     5221 gtttacagca actgtaattc gattattccc gtcttttaca aaccgattaa tttcagactc
     5281 aaatggtgta aacccacctt tgtgttgagt aataaacttt ccattcaaaa aaacttttgc
     5341 ttcatgtgtt gcagatccaa aacgaagaac taatctttct tctaataatc ttttaggaag
     5401 agtcacttct ttttcatacc acacccatcc aacatgattt ctaatgttct ctgtttcaaa
     5461 taaatcatta taagaagagg gaactgaaat cggataactc tctttttcat ttattggttc
     5521 taaagcaagt tcttcctgta agtcatcatt tgtatctaat ttaaatctcc agagaccgct
     5581 taagtcaatt acttgcctcg tctctgtcat aatgggatac aacatataaa ccactcctat
     5641 ctaaatatta aataaatgta tcctttaaac cacaataagc atctattgga cttactccct
     5701 taaattcaga aagacccatt agtttgtcca ccaatatttc taaagtttct tgttttccat
     5761 cataagtatt aatataagtc tttacttgag gtacatcagc caaatgaaac ggacactgta
     5821 cagatacaaa aattgttgga atttcatgaa tgtaaaacgg tatatccgga gttcctttac
     5881 ttgctggcca gacaattcgt tgaactgtgc ctggattaac attagctata ttaatgatca
     5941 agtcatattt tttagttaaa tttttaattg gtctcttagc agcatatatt ccagctatat
     6001 ttttaatttt ttcttcttgc gataatcctt tcaattcttc ttcaggtgaa atgtattttt
     6061 caacttcaaa tccttttgct gacaaaatct gtttcaataa atcaatggct tgaggtctat
     6121 ttccagcaac tacttcacca aacccacctt ttaccccatg tacatctact agtaaaatcc
     6181 ttttatattt ttctggtaca ataggccaaa tatcttgttt atctttaact aatgtaattg
     6241 cttggtcagc cacctcttta aaaattgatt tattttcaat taaaccaatt ttttccagag
     6301 cttcttgctt aggtaataaa atttgttctt ttgctttttt gtgtaatccc aatttagctt
     6361 ttaaccctaa aattcttttt aaggcatcta ataaccgatc atcagtgata attcctttac
     6421 gatagccttc catcatataa ttaaagtctt catctggatc attaaaaaat agaaatagat
     6481 cacatccagc tgcaatagaa gtgggcaata attctgatcg tttcattgcc ccagtcattc
     6541 ctaacatatg actagcatca gtaactacta atccattaaa tccgagtttt cctctaagta
     6601 agtcagtgat taattctttt gataaagttg caggaagtaa atcttcatct ttcagatcag
     6661 gattaaaatg ttttgaataa gctggcatat ggatatgacc tgccataatt gaaggtaatc
     6721 cagcttctat taagcctgag tatacttttc caaaagaatt atcccattct tccgtaccta
     6781 aactattaat actaaaagat agatgctgat ctcgttcgtc aataccgtca ccagggaaat
     6841 gtttagctgc aggcaaaatt ccactctcct gaataccttt catataagct aaactaagtt
     6901 ctaaaacttt atcagggttt tgtccaaaag atcgactaga aatgatagga tttctccaat
     6961 ttctattaat atctacaata ggagcaaaac tccagttaca tccaatagcc gatgcttcaa
     7021 tcccagaaac tctccctaat tcataagcat atttcgcatc atttgttgca ccaattttta
     7081 cttctacacc aacttcagta ccatctgtac aagctccgtt accacctgct tccgtattag
     7141 cagcaattaa tagaggaatt ttactttctg tttgtaagat atagttttga tcatatacct
     7201 catcagcagt tcctggatta tatcgtacag ctccaatatg gtactgattg accatattac
     7261 tcaagtaatt tttatcacga ctagatccca tattaacaaa caattgacct attttttctt
     7321 ccaaagtcat agaatcaatc gtctcttcaa tccaagaaat agcatcttca tctaaattat
     7381 atggtttttt tcgtaaatct acttttatag tcattttctt tctcctctac ttattagtaa
     7441 gatttttcca aaaagtatct atatattttt gttcaatatc tacataatct cccgataaac
     7501 atttaaataa aacatcagtt cttaagtttt cccatgattc tttttcttta ttgaccaaaa
     7561 taggataaaa gaaaacttta tttttatttg cagcttctag atcaccagga gaatcaccaa
     7621 tcattaatat cttatccaaa tcacaaccat tttcaattac acttcgaata atatcttctt
     7681 tttttccttt atcttgacaa cacagttcat caactaatga taataattca tgtctttccc
     7741 attcttcttg aacagcttcc ttattagctg agcttacaat aattatcttc ccatattttt
     7801 tcagagcttt tatagtatct ctagcactta aaaagggttt atctaatcct tttgcttgac
     7861 taatctgttg attgacttct tccgaccatt ttaaagcttt taataaatcc tctgactgag
     7921 aatattctat ttccctcttc aaagatggat tagacaattc ttttgttaga gatacccagt
     7981 gctttaatcg attaatcgat gttacatcat ttttttctaa tgttttaact aaacctaaaa
     8041 atctgtttat tccacgagtc tctgaatata aattaatatt attccaatcc tgtaggaatt
     8101 tttctctatg atgaacatca aaaatctctg cagcaattgg tccgaaaaag agattgtgtt
     8161 tataagtcat cgtatccata acacagccat ctgaatcaat acaaaatatc caattattca
     8221 tatttctctc ctatttatgt ttttgtttta aaagctcgca attttctaag actttatctt
     8281 tagataatgg ataaaggaaa aataaaatta atcctacaat cagaaaacaa attgatggaa
     8341 ttaatgttga agcgttatat aacttttcta aaacatctcc cgtttgtaca tttgctaaag
     8401 agtcatagcc tataatagaa agagtccaac ctccgacgcc tccagctaga gcttgaccta
     8461 tttttctagc aaaagaatat accgcatata cggtcccatc ttctctttga tcagacttta
     8521 cttcttgatc atcaataaca tcagtaatat ttgcccaaat aacagtatta aacacaccca
     8581 aacccatata gccaaccgaa ctaagaatta agaatacata catattacta gcttttatca
     8641 aaaataagat caaatatact attgctgaaa agaacattcc tactgatgcc agttcttttt
     8701 ttccatattt tttacttaaa aacaaagtta aaggcgaaac aactattaaa accaaaatag
     8761 gattgataaa attcattaaa actattccct gtgcatcatt atagtaatca ggaaata
//
LOCUS       DADQCX010000102         8730 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.104, whole genome shotgun sequence.
ACCESSION   DADQCX010000102 DADQCX010000000
VERSION     DADQCX010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.104"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(475..1062)
                     /locus_tag="J8R83_002366"
     CDS             complement(475..1062)
                     /locus_tag="J8R83_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575481.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            1237..2559
                     /locus_tag="J8R83_002367"
     CDS             1237..2559
                     /locus_tag="J8R83_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9575482.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            2714..3490
                     /locus_tag="J8R83_002368"
     CDS             2714..3490
                     /locus_tag="J8R83_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAZ9575483.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            3483..4052
                     /gene="rnmV"
                     /locus_tag="J8R83_002369"
     CDS             3483..4052
                     /gene="rnmV"
                     /locus_tag="J8R83_002369"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAZ9575484.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            4045..4929
                     /gene="rsmA"
                     /locus_tag="J8R83_002370"
     CDS             4045..4929
                     /gene="rsmA"
                     /locus_tag="J8R83_002370"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAZ9575485.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            5380..6009
                     /locus_tag="J8R83_002371"
     CDS             5380..6009
                     /locus_tag="J8R83_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575486.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(6133..7242)
                     /gene="ugpC"
                     /locus_tag="J8R83_002372"
     CDS             complement(6133..7242)
                     /gene="ugpC"
                     /locus_tag="J8R83_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAZ9575487.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            7451..7873
                     /gene="mgsA"
                     /locus_tag="J8R83_002373"
     CDS             7451..7873
                     /gene="mgsA"
                     /locus_tag="J8R83_002373"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAZ9575488.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            8196..>8730
                     /locus_tag="J8R83_002374"
     CDS             8196..>8730
                     /locus_tag="J8R83_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAZ9575489.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
BASE COUNT         2760 a         1543 c         1790 g         2637 t
ORIGIN      
        1 tcaaaggggg tatgacacta gttgtgtcat accccctttt tccgaaattt gagaagcaat
       61 tttcgtaaat tccttcttat tacttgaagc caatcatata atacagaaac agagaactat
      121 ccaaaataaa tcctagaaaa agaagtacga gcttcgctga tttttgttaa tttagaataa
      181 tactaatagg aatcgtaaaa acagaaaaaa agcataatga taaagggtcg ggcagatttt
      241 aattgattca tctggtactc ttttttattg tccttacatt cataaagttt gaatgcaatg
      301 actttattac atctatattt atatctaaca gtagcgttga tgtgttaatt ataagttcta
      361 tcactttatg ttcaattagt ttgtgctctt atatgtgtga ttgaaaatat agataaaaaa
      421 acaatcatcg gctttgactt cgatgattgt tttctttatt ttgtaaaaat cctatcactt
      481 gattttatgg taacctttta tttttgtctt caaacggctt ggtaagagag cagtaagcag
      541 tgcaaatggg atcgaaaaga cataccagaa aatcgtacgt ccgataccat aatgttgata
      601 gagctttgtc aacatcacgt gtaacaagat caaccctaaa agcaaggagc cagctataaa
      661 ccaatgatta tcccaatgca tgacttcact aagtgccatc actccaaaag gatagaaata
      721 aaaatagatc ccgactaagg tcatccgcca gttctttgta aatgttccga tattcaataa
      781 aaagaaaatc gctgaaagca aaataccgat aggcggaaaa agcccaacca aaaaggaata
      841 caacatcccc cacaagatca tcacaggacc tttgatcaat gcaacgattg cgatgaacaa
      901 agtcagcaat attagttttt gtgataacgt tgcaacagtc attaatccaa ataaaattaa
      961 tgtgaaccaa tgccaatggg actgctgttg ttctttacgg gaaaaatcga cccggttgga
     1021 taaataatct gctaatttcg gataagaacg cttaaaatcc ataaactgtt cctccttcgt
     1081 ggaaaaggta ggtttagtat acgaaaaata aaaaagaaat acatccgtct taagagggag
     1141 tttttcactg aaagtggaga aaaaagaatg gtaaattaaa atattctcag ttatactgaa
     1201 aattatacca aatttcaaag aagaaagagg atgggaatga aaggcaaact aaaacgagaa
     1261 atcaatctgt ttggcgcatt agctaccgtt atgggaaccg tgatcggtgc aggcgtcttc
     1321 ttcaaaactg ctgctgttac tgctagtact cagtctacaa gtttgacatt gctagcttgg
     1381 cttttgggtg gtttcttaac gatctgtgct ggattgacag tggctgaatt agctacagca
     1441 atcccggaaa ctggtggagc tgtaaaatat attgaagctg cgtatggaaa attgcccagc
     1501 tttttattag gatgggcgca aagcttgatt tactttcctg ctaatattgc tgcattatcg
     1561 attatctttg cgacacaatt gacgaactta ttacaattat ctaccgatta tcttttgttg
     1621 attgcagtga tcaccgctgt ttctgtgaca gggttgaatt tgttagggac aaaagtcggt
     1681 gcttctgtac aatcagtgac gttgattgtt aaattaatac caattgctgt gattgtcata
     1741 tggggattat tgaccccagg acaaggaact gtccagttat ttccaatcga agctggaaaa
     1801 gatgttactt ttgtcgaagg attgagcagt gcgttgttag caacgttgtt tgcttatgac
     1861 ggctggttag gtgtcggtgc aatggcaggg gaaatgaaac ggccggaaaa agatttgcct
     1921 aaagcaatta ttcttggttt gagttttgta acagtcgttt atctattgat caattttgtt
     1981 tttttgaaaa ctttgccgat tgatcatctt gccggtaatt tgaatgcagc ttctgaagca
     2041 tcagacgtca tttttggagg aatcggtgga aagctggtca ctattgggat cttgatctcg
     2101 gtatacggtg cattgaacgg ttatacacta actgggatcc gcgtgcctta tgcgatggct
     2161 ttagaagacg agctaccttt cagtaaacag ctgacaaagc tttcaaagaa gtttacggtt
     2221 ccttatgttc ctgcggtttt ccagttagca gtagcttgta ttatgatgag ccttggttct
     2281 ttcgactttt taacagacat gttgattttt gtgatgtggc tattcagttt actgattttt
     2341 atcggtgtct ttattttaag aaaaaaagcg ccggaattgc cacgtccata taaagtacca
     2401 ctttatccaa tcgttccgat tattgcgatt ctcggtgcta ttttcatttt aggtatgacg
     2461 atgatgacgc aaacgaaatt agcattgatc ggtataggtg ttaccttgat aggtatccca
     2521 gtctattatc aaaaaaagaa aaaacgctca gaagagtaaa atatttcaac aacagacaga
     2581 aaaagtacga actaggtcct ctagatcttc gtgctttttc tatttcaata aaacaagttc
     2641 ttctattttg atttttgcta cttctgcaag tagtgcttat gtgctaaagt aagaatgaaa
     2701 aggagagata aacatgatat ttgattctca tacccattta aatgctgaac agttcaatga
     2761 agatattcca gaaacgattc agcgagcaca agaaatgggg gtaacgaaaa tggcggtcgt
     2821 gggcttcgat acgccaacga ttgaaaagtc tttgcaatta agccatgact atccaaatat
     2881 atacagtatt atcggctggc atccgacaga ggctggcagt tatacgaaag aaatcgaaaa
     2941 taaattacaa gaacaattga ctttaccaaa ggttgtagca ttaggggaaa ttggcttgga
     3001 ttatcattgg atggaagacc cgaaagaagt ccaagataaa gtatttcgca gacagattgc
     3061 tatcgcaaaa gaaatgaacc taccaatcag tattcatact agagaagcac ttgaagacac
     3121 gtatcaaatc ctaaaagaag aagatgttcg agatatcggt ggaatcatgc atagtttcag
     3181 tggtgattat gaatgggcaa aacgatttct tgacttaggg atgcatattt catttagcgg
     3241 tgtcgtcact ttcaaaaaag cattagacgt ccaagaggct gcagcaaatg taccaatcga
     3301 acgattactt gtggaaacag atgcccctta tctggcacca gttcctttta gaggaaagcg
     3361 aaatgaacca ggctatactc gttatacagt agaaaagatt gctgaacttc ggaatcttcc
     3421 gacagaagaa gtggctgccc aaacatggac aaatgcgcac cgattatttg gtctaagcga
     3481 acatggataa gatgaagatc caagagatta tagtcgttga aggaaaagac gatacaagaa
     3541 ggctgcggga agtagttgat gcagatacga tagaaacaat agggtctgca atcaatgaag
     3601 agatcctgat gcaaattgaa catgcccaag agactcgtgg agtgatcgtt tttaccgatc
     3661 ctgatttttc aggagaaaaa ataagaaaaa tcattatgga agctgttcct caggcaaaac
     3721 atgctttttt gccgcgcaca caagctaaac caaagaaaaa gggaagcctt ggtgtcgagc
     3781 atgcaagtga tgctgctatt ttagaagcat tgaaaaaggt cgtgacgcca gacatttccc
     3841 aaacggctgt ttctgaaatc actagacaag accttttaga ctatggttta atagctgggg
     3901 cacaagcaaa agaaaaacga gaaaaactag gtgacgagtt gcgcatcggt tacacgaacg
     3961 gcaaacaatt ggaaaaacgt ttgaagatgt ttcgtattac gccgaaagaa ctcgcccaag
     4021 caatgaaaat agtggaggaa caacatgagt gaatatcgtg aaattgcgac accctctaga
     4081 acaaaagaga ttttattgaa acatggtttt tcatttaaaa aaagtttagg acaaaatttt
     4141 ctgactgaac caaatatttt aaggaaaatc gtagaaactg cgcaaataga tgaacatacg
     4201 aacgtgatcg aagttggacc aggaatcggt gcattgacgg aacaattagc caagcatgca
     4261 aaacaagtcg tagcatttga gatcgatgat cgtttgatcc ctgtattggc tgatacgatg
     4321 caaccctatg acaatgtgac tattgtacat caagatattt taaagaccga tttgtcaaca
     4381 gctgttagag aaacatttca tgaggagctt ccgttaaaag tcgtagcgaa tttaccttac
     4441 tatattacga caccgatcat gatgcatttt cttgaatcag atttggttgt ggatgaacta
     4501 gtcgtcatga tgcaaaaaga agtagctgat cgtatctctg ctgaaccagg aacgaaagct
     4561 tatggttcat tatcgattgc tgttcaatat tatatggaag ccagtttagc attcatcgta
     4621 ccaaaaacag tatttgtccc tcagccaaat gtagattcag cgattttgaa actgacaaga
     4681 agagatatac cggcagtcga agtgacagac gaaaaagcat ttttccgatt gacaaaagcg
     4741 gcatttcagc aaagaagaaa aacgctttgg aataacttgc agcattcgta tggcaaagat
     4801 gaccagacaa aagcatggtt agcaaaaagc ttggaaacag ctggaatcga tccaaaacgt
     4861 cgtggggaga ctttgtcatt acaagaattc gccgcattaa gcaatgcgat gtcagaaaat
     4921 atgcagtaaa aaaagaggtt gtgacagaag ttgtgaaaaa gctgtcctgc atcaagtaat
     4981 aagaacagcc aaacaaaaat agttcctcat gtttttcgtt tgtttgggct tattaccgca
     5041 gatgcaagct tttgaacacc gtttaagaaa gaggttgtgg gcctgccgtt taactctaag
     5101 tcacaaggaa caatttcaaa aaacagcttc tcatgttttt gagttagttg gtcttattac
     5161 ttgatgcaag cttttgacca ctattatgcc gaacaaggag atgtgacaca aattttgtca
     5221 catctcctat ttttgtttct tgatcaaaaa attcttatac ttgatactca cactcatttt
     5281 gtatggattt agaaaagaat atgtgtcttg acagttatta gtaagtgagt tatactaagt
     5341 cgacatttat gtgtcaagac atattaggag agagaaaaaa tgagaaaaaa ttcagttcga
     5401 aaactaacga tttctgcttt attgattggg atgggggtca ttatcccaat ggtcatgcct
     5461 aaaatcatga ttccaccagc ttcctttact ttggcgtctc atgtgccatt atttattgcg
     5521 atgtttttta caccaggagt tgcagtggct gttgcgctag gtacgacatt tggtttcttt
     5581 ttaacaacgc cggttatcat cgcattgcga gcattgtcac atcttgtgtt tgcgttgatt
     5641 ggggcttggt acttgcaaaa gcatccgagt atcgttttaa aaaatggaca gtttactttt
     5701 gctaattggc gtttccaagg gttcaatttt gtgatcggtg tgattcattc tttagcagaa
     5761 atgctagtag tcagcatctt ttactttatt ggtaatatgc ctgaaacata ttattctcaa
     5821 ggatattttt atacagtatt catcttgatg gggattggtg ggcttatcca cagtttagtt
     5881 gattataata ttgcttattt tatagcagga acactcagca aatattttga tatccccgta
     5941 tttacggcag caaaaaaaga aaatcggaaa gagtcgattc aagggtacgc gaagaaaacg
     6001 acatattaga catgatctct caaaaaaaaa actctcatct agtaatggat aataaatcct
     6061 ctaagatgag agttttttgt cctaaaaaga gctgcaccaa catcttctgg cacagctcta
     6121 acagggggca atttatggaa gtttgatgac ttgttctgtt tctttatcaa agaagtggcc
     6181 tttgctgatg ttgaaggcaa ggtcgactat ttcgcctggt ttatggaaat ctcttgcatc
     6241 tacttttgag atgaactcag tagaaccagt ttttgtgtaa agcatcgttt cagctccaag
     6301 taattcggaa acgacaactt ctgatttcac tacggcttca ggtgaagctt caagggctac
     6361 ttgttcactg tggatgtctt ctggacgaat accgaagata acttcttttc cttcataacc
     6421 tttttcaact aatactttgt tttttccttc aggaatacga agcttaagcc catgtccatc
     6481 tgtgataaca ccatttttca atgtcacatt aaagaagttc atggcaggag atccaataaa
     6541 gccggcaacg aacatattga cgggtgtatc ataaacttct ttcggtgtac cgatttgttg
     6601 gataaatccg tctttcatga taacgattcg gtcagccata gtcattgctt ctgtctgatc
     6661 gtgagtaaca tagatggtcg ttgtttcaag acgctggtga agtttggcaa tctcagcacg
     6721 catggctaca cgtaatttag catctaaatt tgataatggc tcatccatta agaagacttt
     6781 tgcatcccga acgattgccc gtcccaatgc cacacgttgg cgttgtccac cagataaagc
     6841 agctggtttt cgtttcaagt attctgtcag acctaagatc tctgctgcat tgtccacacg
     6901 ttttttgatg tctgctttat catatttacg taatttcaag ccaaaagcca tattatcaaa
     6961 aacagtcata tgaggataca atgcgtagtt ttggaaaacc atggcaatat cacggtcttt
     7021 aggtgccacg tcattcatga cttttccgcc gatatttagt tctccttcag agatatcttc
     7081 cagtcccgcg atcattcgca aagtagttga ctttccacaa ccggaaggac caacaaaaac
     7141 gataaattca cggtctttga ttgatagatt aaaatcagtt acagaataat tttctgcatt
     7201 gtcatatttt ttatatacgt ttttcagagc catttctacc ataatacgtt ccacactttc
     7261 ttttttagtt ttattaacta tttaaagtat aaatgaaagc gttaactaac ttcaatgtca
     7321 tgttgaacaa gaattttttc ttttttttgt caatgtgcta gttttaagct ttaataaata
     7381 tccataagaa ataaaaactg atacactgga gtaaataagt atgttaacaa tatcaaaagg
     7441 agtgtctctt atgaaaatcg ctttgatcgc tcatgaccga aaaaaaccta tgatggtgaa
     7501 attagcaaca gcgtataaaa caatattgga aaaacatgaa ctttttgcta ccgggacgac
     7561 tgggcagagg atcacggaag caaccggctt gccgatccat cggtttaaat ccggaccgtt
     7621 aggcggggat cagcaaattg gagccatgat ttcggaggat cagttagatt tggtgatttt
     7681 tcttcgagac ccgctggctg cacagcccca tgaaccagat gtaacagcac ttatccgttt
     7741 atctgatgtc tatgagattc cgttagctac gaatatcgga acagctgagg tgctactaag
     7801 aggactggaa gccggcttcc tagattttcg aagaatcgtc catgaaatag acaagcatcc
     7861 actttcattt tgatggataa gcgtatggaa aaataacgtt taatgttcgc ctatatgtag
     7921 ctataaaagc taaacaaact gataatatgc gatataatac gaacgtattg gataatataa
     7981 acaataatat tagtttttcg tatttgcagt aaatgtgaaa atatgctata gtttctgtgg
     8041 gaaaagatcc caaaaataat acagagtaga aaataaagcg ttaagtgcta agaggatggg
     8101 atgttgcctc ttggacgaag gacgtaatgt tcgcggtttt attttcgcat tcgctgcatg
     8161 atacgatgta gcagctctta aaggagatgc taaaaatgaa gaaacaccgg ttagacgcac
     8221 gtatgattgc tattatgggc ttattgattg cattgatggt cactttgtcc cgactggtag
     8281 caatcgagac cccatttatt aaaatcagtg tcacatttat tccacaagtg atcatgggca
     8341 ttctttttgg tcctttttgg tcagggatag gcgcagtttt agctgattta gtaggaatgg
     8401 ccctcttctc gaaatctgca ttctttattg gatttacatt gaatgcattt attgaaggag
     8461 caatctacgg attctttttc tatcgaaaag agatcacttg gaaaaatgcc attctggcta
     8521 cgcttagtgt cacgctgatc atcaacttat ttttgacacc attatggctt gcgttgatgt
     8581 accatgtgcc attgttcagc tgggtcgttt gggcgccccg cctgttaaaa acagtaatat
     8641 ggttaccgat tcaatcaatt gccatttatt acgtaggacg tagtattcct tacaaaaaaa
     8701 ttttaagaag tttagcgatc cacgctaaat
//
LOCUS       DADQCX010000103         8555 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.105, whole genome shotgun sequence.
ACCESSION   DADQCX010000103 DADQCX010000000
VERSION     DADQCX010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.105"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="J8R83_002375"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="J8R83_002375"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAZ9575490.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="J8R83_002376"
     CDS             complement(1098..2201)
                     /locus_tag="J8R83_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAZ9575491.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /locus_tag="J8R83_002377"
     CDS             complement(2291..3226)
                     /locus_tag="J8R83_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAZ9575492.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="J8R83_002378"
     CDS             3528..5462
                     /locus_tag="J8R83_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9575493.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="J8R83_002379"
     CDS             5919..6335
                     /locus_tag="J8R83_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAZ9575494.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="J8R83_002380"
     CDS             6349..6915
                     /locus_tag="J8R83_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAZ9575495.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="J8R83_002381"
     CDS             6938..7924
                     /locus_tag="J8R83_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAZ9575496.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8555)
                     /gene="scm"
                     /locus_tag="J8R83_002382"
     CDS             complement(8079..>8555)
                     /gene="scm"
                     /locus_tag="J8R83_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAZ9575497.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2516 a         1650 c         1739 g         2650 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt cacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacgagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgttgt ggtagatgta
     8521 tccgtactgt cgcttgaagc tgacgtgtcc gtgct
//
LOCUS       DADQCX010000104         8542 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.106, whole genome shotgun sequence.
ACCESSION   DADQCX010000104 DADQCX010000000
VERSION     DADQCX010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.106"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            194..1387
                     /locus_tag="J8R83_002383"
     CDS             194..1387
                     /locus_tag="J8R83_002383"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAZ9575498.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1517..2989
                     /locus_tag="J8R83_002384"
     CDS             1517..2989
                     /locus_tag="J8R83_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9575499.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3072..3860
                     /locus_tag="J8R83_002385"
     CDS             3072..3860
                     /locus_tag="J8R83_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAZ9575500.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(3927..4595)
                     /locus_tag="J8R83_002386"
     CDS             complement(3927..4595)
                     /locus_tag="J8R83_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAZ9575501.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            4710..6422
                     /locus_tag="J8R83_002387"
     CDS             4710..6422
                     /locus_tag="J8R83_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575502.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6425..8197
                     /locus_tag="J8R83_002388"
     CDS             6425..8197
                     /locus_tag="J8R83_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575503.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8279..>8542)
                     /locus_tag="J8R83_002389"
     CDS             complement(8279..>8542)
                     /locus_tag="J8R83_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9575504.1"
                     /translation="KNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTEL
                     GIPLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         2607 a         1418 c         1865 g         2652 t
ORIGIN      
        1 tttatggatg attgtgctaa gcttttttgg acagttctaa tgtaaaatat ttttatattt
       61 tttaagcaaa aaaatgaaaa aatacgagca gaaaactgtt ttatctgcta tacttggttc
      121 gttgcaagtt cccgaaagga tccgcaggac ggagatgcct tgtaaccgaa tttaactagg
      181 gggaatcatt ataatggtag aaagacactt atttacatca gaatctgttt ctgaaggaca
      241 tccagataaa attgctgacc aaatcagtga tgcaatcttg gatgcaattt taaaacaaga
      301 tccaacagca cgagtagcgt gtgaaacgtc tgtaacaact ggtcttgttt tagtatttgg
      361 agaaatatct acgacggcat atgtagatat tcaaaaagtc gtacgggaaa caataaaaga
      421 aattggttat acacgtgcaa aattcggatt tgatggagat acagcagctg tattggttgc
      481 gattgatgaa caatctcctg atattgctca aggagttgat gaagcacttg agatccggga
      541 tgaagataaa aaagacgtat tagatgagat tggtgctggt gaccaaggtt taatgtttgg
      601 gtttgctgta gatgaaacac cagaattgat gcctttacca atcgctttga gtcatcgtct
      661 ggtacgacgc ttggcagatt tgcgtaaatc aaatgaatta acgtatttac gtccagatgc
      721 aaaatctcaa gtaacggttg aatatgatga tcaaggacaa ccggaacgcg tagatacaat
      781 cgttatttca acacagcatg atgatgcagt agataatgaa acaattcgtc atgatgtcat
      841 cgaaaaagta gtgaaggaag ttattccagc tgaattatta gatgatcaaa cgaaatatta
      901 tatcaatccg actggccgat ttgtcattgg tggtcctcaa ggggatgccg gattaacagg
      961 aagaaaaatc attgttgata cgtatggcgg ttatgctcgt catggtggcg gtgctttttc
     1021 tggtaaagat gcgacaaaag ttgaccgttc tgccagctat gctgcacgtt atattgctaa
     1081 aaacattgtt gcagcagggc ttgctcgcaa agcagaagta cagctagctt atgcgattgg
     1141 tgttgctcaa cctgtttcga tctcaatcaa tactttcggt actggaacgg ttccggaaga
     1201 agaactgatt gctgcagtga gagaaaactt cgatcttcgg ccagcaggaa tcatcgagat
     1261 gcttgatttg cgtcgtccga tttacaaaca aacagctgct tacggtcatt ttggtcgtac
     1321 agatgtagat ttgccttggg aacatacgga caaagtagat gcgttgaaag caagtttagc
     1381 aaaataagtt atattcagct ggaacgatcg ccaagtggtg gttgttccag ctttttttat
     1441 ggcagttaac ctcttgaaaa agatagtaat tatttatcta tttttagatc ctgtcataat
     1501 gaaagggagg aataagatga aaaaagaaac aaatgttact ttggtcacag tgagtatttt
     1561 cattgcaacg ttcatgacgg ctattgaagg tacaatcgta acaaccgcta tgccaacgat
     1621 tgtcggttca ttacatggaa tggaaatcat gaactgggta ttttcgattt atttgctgac
     1681 aaacgctatg cttactccga tttacggaaa acttgcggat aaagtgggac ggaaaccaat
     1741 ctttattttt gggacattat tgtttattat cggttcgtta ttttgcggtt tatctcaaag
     1801 catgattggg ttgattgctg ctcgtgcgat tcaagggatg ggtgctgggg caatgatgcc
     1861 agtagctttg acgatcatcg gcgatcttta ttctattgaa aagcgagcaa aagttttagg
     1921 tttgaatagt tcagcctggg ggattgccag tgtttttgga ccgcttgcgg gaggattcat
     1981 cgttgaaacg atcagctggc actggatctt ttttatcaat gtgccgatcg gaattctatt
     2041 aattattttg atttggctat atttaaatga accaaaaatc atacatgagt ctaaaccaat
     2101 ggatattttt ggtagtttta gtttgatggc catgcttgtc tcattgctgt tagggttcca
     2161 attattagga gacgaaggaa tgagtccgct tgtttctgct ttgctgctag gtagtatcgt
     2221 aatgttaggt atttttgttt ttgccgaaaa aagagctaaa gatcctgtca tcatgatgca
     2281 tttattcaaa aatccactat ttgttgtggt caacttggct gcagcattgg ctagtggttt
     2341 tttgatggga atcgatgttt atatccctat gtggatgcaa ggtgtattag ggctgaatgc
     2401 agcaattggt gggctggtat tagcaccatt atcactagtc tggatggtcg gttctttcct
     2461 tgcaagcaag tggatgactc aaatgaaaac tcattgggtc ttgagaattg gactactaat
     2521 cgcagctatt gggggcgctt ggttgtatct tatgcctttc agaagtaact atttatggtt
     2581 ttttgctata tcaacggtca tcggtatagg cttaggtgtg accatgacta cctcgactgt
     2641 cagtgcacaa aatagtgtat ctcgtgacca gcttggtgta gcaacttctt ttaatacgtt
     2701 agttcgaaca attggtcaaa cagtcatggt ttctattttt ggtttattga taaatggggt
     2761 aactaaacga gaacttgcag cagcaaattt aacaaatgat gcagatatca tgaataaact
     2821 ggtgaatcca caaacggcta aatatattga tgcggatatt ttgttaccat taagaaaaat
     2881 tctttatgat gggttacatt ccgtttatct agttggcttg ttactcgtga tcattgcttt
     2941 ggtcttaacg cttttcgttc atgaaaaaag tggtaaaata aaacagtagt ttcggttaag
     3001 atatgtacgt agccgaatca ttcaaattta aagttattca aaaataactt cttactaagg
     3061 aaggcgaaaa tatggcattt attcaagcaa atatttattc gaatgtgtta gaaatggaag
     3121 tcaatctaaa tgtgatacta ccgcaaacaa caaaaaaggt gattggcacc agttcagagc
     3181 aagagacaac ggatatacct gttttatatt tacttcatgg aatgggtggc aatcatagtg
     3241 tatgggaaag acgtacgtcg attgaacgtt atgtagcaaa ctacggatta gctgtcatca
     3301 tgccatctac tgatcttggc tggtacacag atacagttta tgacatgaag tattggacat
     3361 tcattgcaga agagctacct gagatttgtc atgaattatt cccgcaatta acaagaaaaa
     3421 gagaaaaaac atatgccgct ggattatcga tgggcggata tggcgcgtta aaactaggcc
     3481 ttgcaaaatc agaaaatttc gcagcagtaa tctctctttc aggcgctgtt tctgtaggaa
     3541 atcgaatgga tgatcttttg atggttcgta aagcatcttt ttgggaaggg atctttggac
     3601 cattggatca aatcgaaggt tcaaaaaatg atccgcaata cttattgaaa gaactagtaa
     3661 aaagcggaaa accagttcca agattttata tggcttgtgg ggaatctgat tttctttatc
     3721 aggcaaatca ggaaatggta tctgctatgc aggaacaagg cttggcggtc acctttgaac
     3781 aaggacctgg cgatcataac tggatcttct gggaccaatg gattcaacgt gcattggcgt
     3841 ggctaatgga agaaaaataa aaaaagagtc ttaaaaagat agctcctata gagatcacaa
     3901 acatagtgat ctctatagga gcttttttac tgctcgtttt ctcttctttt attttgttgg
     3961 cataagcctt caatataggt ttgtgcactc gttagaaaga gtgctttttc attcaattct
     4021 gcatgggact gcatactttc tttaaatccc tctaattgat tttcaactac ataattacgc
     4081 ataaatagaa ctgtttcttt caaaaattca tttccgtcca taattttttg tcgaagctgc
     4141 tgttcatgct gctgatccat taactgtcca atcaataaat tgtggagaga ggcaatggcc
     4201 tgatgacttt gggtgactga aaatccttca cgaacaagta attggatcat ttgctccaaa
     4261 tgttctaatc gactcggaaa agcgggcaca gtattgattt ctaattctgc cccacaaggg
     4321 aaacgtgtat aaaggtcata gtaattttcc atatactgca gcaactgttc attccaaggc
     4381 aaagttggat ctggaagcgc taattcttct tccattgttt cagccattat ttgcaagagc
     4441 tgttgtttgt ttttgaaata ccaatataaa gcaggtgctt gaacatgaat tctgtttgcg
     4501 atgtttcgca tggaaagctg cgaaagagct tgtgtttcag ccaggatatc aaaggcggcc
     4561 tgaatgatga ttgcttgaga aagctttatt tccattttat caacctcgtg tattgcatta
     4621 tctttttaaa catggtaaat tgttagtcgg tctaatttta cagtgttaaa ttagtcctgt
     4681 caatttaaac aaaggggtgt aatcaacgaa tgaaattaat cttacgacat gcgaaaaaat
     4741 ataaagtagc tgtttttatt tccttgctgt ccgtagcagt catggttgca gcagcattat
     4801 ggcaacctaa gttactacag caagtattgg aagctattat tacagaagat aatgatgaaa
     4861 tgaaaacaat tggtatttac ctgatcagtc tggctttgct aggattagcc gcaggtgtaa
     4921 cgaacacgat tttctctgca aaagtagctc aaggcgtaag tgcagatatc cgagaagaag
     4981 catttcgaaa gatccagaca ttttcatttg gaaatatcga acagttctct gctggaaatc
     5041 ttgttgttcg tctaacaaat gatatcacgc aaatccaaaa tttagtgatg atttctttgc
     5101 aatcactttt tcgaattcca ttcttattta ttggtgcctt cattttagct atgatcacga
     5161 tgccgcaatt atggtggatc atcgtagcgc ttatcgttac ggtatttctg attacggcac
     5221 tttcatttac aaggatgggc aagcacttca tgatcattca aaaactgatt gatcgtgtga
     5281 atagcattgc aaaagaaaac ttactaggga ttcgtgtagt gaaatctttt gtacaagaag
     5341 aaaaccaatt gaagtcattc agcaaagtaa gtgaggactt aacaaaacac aacatcatag
     5401 tcggtacatt attttctgtg atgatcccgt ccttcatgct ggctgccaat ttggctgtgg
     5461 ttggggcgat cttttttgtg agcgatcttg ttaaagatga tcctacgtta attggtggaa
     5521 ttgcttcatt catgaactac ttgatgcaga ttatgatggc aatcattatt ggcggaatga
     5581 tgatgatgat gacttcaaga gcagccgtat cgctgaagcg gattgcggaa attttagatg
     5641 ctgaaccaga tcttacttat ttagacgttc cagaacaaga gttgacgggt tctgtcactt
     5701 ttgaccatgt ttcttttcgt tatcctggtg aggatacaga tacgcttaaa gatatcagct
     5761 tttctatcaa acctggagaa atggttggta tcgtcggggc gactggtgcc gggaagtcaa
     5821 cactagcaca attgatccct cgtctatttg atccgacaga aggcaaagtt gaagtaggtg
     5881 gtgtagatct tcgtcaagta aatgaaaaga gtttaagaca aacggtttcc tttgttttgc
     5941 aaaaagcaat tttattctca ggaacgattg ctcaaaactt gcgccaaggg aaaaagaatg
     6001 caacagaaaa agagatggaa catgcttctt ctattgctca agcaaaagaa ttcatcgaaa
     6061 agttatctga tcgttacgaa gcaccaatag aagaacgtag cagtaacttt tctggtggtc
     6121 aaaagcaacg tttatccatt actcgtggcg ttatcggtaa tccaaagatc ttgatcctag
     6181 atgacagtac gagtgcactg gatgctcgct ctgaaaagct ggtccgagaa gcactcgatc
     6241 gagatttgaa gggaacaacg acgattgtca tcgcacaaaa aattgcttct gttgtcaaag
     6301 cagaccgcat cttagtattg gatgaaggca gattagtcgg cgaaggaacc catgaggaat
     6361 tggtagctgg aaaccgtgtc tatcaggaaa tctttgaaac tcaaaaagga acggaggagt
     6421 aagtatgact gatctaataa aagcaagtaa atttttctat cactatttga agcggtacaa
     6481 actctccttt ttctttatct ttatcacagt gatcattgct acctatctac aagtaaaggc
     6541 acctcaatac atcggggaag cttttcaaga attagctaat tacgtaggag gcttgatgca
     6601 aggcgtagac gataaaagca aatttgtttc tgtaatatgg aaactcttgc tgttttatgt
     6661 actagctagt gcagccaact ttatctatag tattttgttc acacaagtag tagggaagtc
     6721 aacgaaccga atgcgtatcg gtctattcaa caaattggaa aaattgacga tccgtttctt
     6781 tgattctcat caagacggtg aaattttaag tcgttttacc agtgacttag ataatattca
     6841 aaatagtttg aaccaagctt tgcttcaagt catcacgaat gctgttttac ttgtcgggat
     6901 cttgatcatg atgttccgcc aaaatgtaga gttagcttgg gctacaattg cttccactcc
     6961 agtagccgtt ttgatagctg tcttgattat ccgcaaagca cggaaatatg tggatcttca
     7021 gcaagatgaa gtggggaaac taaatggtta tatggatgaa aaaatcagcg gacaacgtgt
     7081 catcatcaca aatggcttac aagaagaaac gattgaagga ttcttagagc ataatcaaag
     7141 tgttcgcgaa gcaaccttca aaggacaagc ttattctggt ctactatttc cgatgatgca
     7201 aggaatgtca ctggtcaata cagcgatagt tatctttttc ggcggctggt tagcattaaa
     7261 tggtgatttg gaacgttcgg tggcattagg cttagttgtg acattcgtcc agtattcaca
     7321 acaatattac caaccactga tgcagatttc atctggatac agcatgatcc aattagcgat
     7381 tacaggggca agacgattga atgaaatatt tgatgaaaaa gatgaagtca aaccagaaaa
     7441 ctgtaaagca tttgatggtg ttgaaaaagg tcttgcgttg cagcacgtag attttggtta
     7501 ttctccagaa aaactagtct tgaaagatgt ctcgatcaat gtggacaaag gagaaatggt
     7561 tgctcttgtt ggtccaacag gatcggggaa aacgacgatc atgaatctgc taaaccgttt
     7621 ttacgatgtc aatgatggtt cagtagtcat cgatggaata gatatccgag attatgatct
     7681 tgatgcatta cgtagacatg taggaatcgt tttgcaagaa tctgtattgt tctccggaac
     7741 gatcaaagac aatatcacat tcggcaaacc ggacgcttca gatgaagaag tcatcaatgc
     7801 agcaaaacaa gcgaatattc atgacttcat catgacgtta gaaaaaggtt atgatacaga
     7861 gatatccgaa gaaaataact tattcagtac aggtcaaaag cagttgatca gtattgctcg
     7921 aacgatcatc acaaatccat ctttattgat tttggatgaa gcaacaagta atgtagacac
     7981 ggtaacagaa gcaaggatcc aaaaagcaat ggatgaagca atcaaaggaa gaaccagctt
     8041 tgtgattgct caccggctga aaacaatctt gaatgcagat agaatcgttg tcttgcgtga
     8101 tggggaagtc attgaagaag gcagtcatca cgagttatta gcagaaaatg gattttatgc
     8161 ggaactttat cataatcaat ttgtatttga aagttaaatt aaaagaacct cgttataacg
     8221 gggttctttt tatatatttt atgttgtttg tttttataag gggcagaaaa ggggcaattt
     8281 aaatttctat ttttcctagt ttttctacta gttgattttg catattttta gttgtatgag
     8341 tataaatctt taatgttgtt tttgaatctt catgtcctac acgatccata atggctttta
     8401 atgggattcc taattctgta agtagagaaa tgtgggaatg ccttaacatg tgagaagaaa
     8461 cttttttatc taggtttaat tctttggata ctgctcttaa agattgatta tatgcttgaa
     8521 tagatatcgg gttaccattt tt
//
LOCUS       DADQCX010000105         8279 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.107, whole genome shotgun sequence.
ACCESSION   DADQCX010000105 DADQCX010000000
VERSION     DADQCX010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.107"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..381)
                     /locus_tag="J8R83_002390"
     CDS             complement(<1..381)
                     /locus_tag="J8R83_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAZ9575505.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLD"
     gene            complement(511..1221)
                     /gene="budA"
                     /locus_tag="J8R83_002391"
     CDS             complement(511..1221)
                     /gene="budA"
                     /locus_tag="J8R83_002391"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAZ9575506.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(1234..2898)
                     /gene="alsS"
                     /locus_tag="J8R83_002392"
     CDS             complement(1234..2898)
                     /gene="alsS"
                     /locus_tag="J8R83_002392"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAZ9575507.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(3103..3765)
                     /locus_tag="J8R83_002393"
     CDS             complement(3103..3765)
                     /locus_tag="J8R83_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAZ9575508.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(3775..4590)
                     /locus_tag="J8R83_002394"
     CDS             complement(3775..4590)
                     /locus_tag="J8R83_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9575509.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(4852..5295)
                     /locus_tag="J8R83_002395"
     CDS             complement(4852..5295)
                     /locus_tag="J8R83_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAZ9575510.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(5429..5767)
                     /locus_tag="J8R83_002396"
     CDS             complement(5429..5767)
                     /locus_tag="J8R83_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9575511.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(5755..6132)
                     /locus_tag="J8R83_002397"
     CDS             complement(5755..6132)
                     /locus_tag="J8R83_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9575512.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            6356..7549
                     /locus_tag="J8R83_002398"
     CDS             6356..7549
                     /locus_tag="J8R83_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9575513.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(7715..8137)
                     /locus_tag="J8R83_002399"
     CDS             complement(7715..8137)
                     /locus_tag="J8R83_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9575514.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT         2424 a         1676 c         1401 g         2778 t
ORIGIN      
        1 atctaaaaca ccgattaaat taccttcttt taccattggc actacgattt ctgattgtgc
       61 ggctgaatcg caggaaatgt aatttgcatg ggttttgaca tcatcaacga tcaatgtttc
      121 ttgtttttca gctgattctc cacaaactcc ttttcccatc ttgatacgtg tgcaagaaac
      181 tcgcccttgg aacggtccta aaatcaattc attaccatcg aataaataat atcctgcaaa
      241 gacagtctca ggcaaagtct cattcaacaa tgcagatgaa tttgctaaat ttgctaacca
      301 gttatcttct gcttctaata atccttgttg ctgtaataat aaaatttcgt atgcatcttt
      361 tttctgtttt tctgtccaca tgataaaaac cgctcctttt tgatctatgg agaagattat
      421 agctcagttt ttttgtaaac gctaggtttt ctcctcaaaa aaacgagata cgtcaggtta
      481 atcaccttga acgcatctcg ctgtcttttt ctattctgct tgttggattt ctgctgctaa
      541 atcagcataa tcaatcgttt cgtgaacaaa agtcggatca tcaactggaa aatgctgtac
      601 aagggacgag atgcggctaa tctcaacttt tccttcagcc acttcaaaat ccattacatg
      661 tccgccaaat gtatgtgtat catcgataaa atgcaggtga aatcccgctg cagcaactcc
      721 ttggaataat tcaggcgtaa agaacccgac taatgttcct tggacattgc tttgttggaa
      781 ttctggttga gactctgaaa tttttgctag tcttctgtaa ggtttttctt gcttcggcat
      841 gatacggatg tgcatatttt tgaataatcc agttatcttc actgccaaaa ataggttttc
      901 cccggcttct cttactaata tgtctttttt caattgttct ccatctgcag tttttgagac
      961 agaaaaacta gtatctggcg taaaatctgt aattgctgca tagggggtaa gttcacttcc
     1021 atctaattgg gcaactgagc catctgatct tccttgataa gctacgccat ctaaaaagat
     1081 gacttcacca tcaagcccat gcaatgttcc caatcccaga gttccttttt ctaatatatg
     1141 agcaatcgtt tctgttccat ccatcaagcc agccatcaaa gctcctaatg tcccgtgctg
     1201 gtataagatt ttttcagtca tgtcgacact tccttaatag aattgatctg gtaagattgt
     1261 ttctcccaat ttctcattat cacggtaatc aatcggaata tcaataatta cgggtccttc
     1321 tgtcgcaaat ccttcttcta aagctttttc taattcctct acacttgtag ctcggattcc
     1381 tttagcgcca aaagcttctg catatttcac aaaatcaact ggaccaaagt ctacacctga
     1441 cgcccgctga tatttcattt tttcttggaa ctctaccata ttgtagtgtc catcattcca
     1501 aatcaaatga acgatattca attttttacg taccgccgtt tctaaatcct gggcagagaa
     1561 taaaaatccc ccatcgccgg aaactgatac gatttgtgta tttggacgca ccaatgcagc
     1621 agaaatcgcc catggcaatg caacaccaag cgtttgcata ccattactga ataacaaatg
     1681 acgaggttca taacttctaa agtggcgtgc catccaaata taatgactac ctacatctac
     1741 ggtaacagtc atatcatctg ttacttttga ctgaagcgtg ttaataactt ctaaaggatg
     1801 caagatacct gcttctcctt ttgattgaac aatgtcccgc tccgttaatt ctgcttgaag
     1861 agatgctaaa tattcttttg catcttctga cacttgttga ggctctaatg aacctgtcaa
     1921 taaatcaaga gtggctgaga tatcaccgat caattctctt tcaggctgca taaaaggatc
     1981 gatttcagct ggcgcttcat cgatcacaat gatccgcgca tctttttccg cattccagtt
     2041 tcttgcttca tattcgattg gatcatagcc aatagcaata actagatcac ttcgtttcaa
     2101 aagcatatct cctggttggt ttctaaataa acccacacga ccaaagaaat gcgcttctaa
     2161 ttcacgtgag atcactccag ctgcttggaa tgtctctaca acaggcaatg ctgtctttcc
     2221 aactaattgc ctgatggcta acgtttcttt ttcacttgat cctcgcatac ctactaatag
     2281 taccggtagt tttgcttctc taatgcgttc agctaggtaa cggatatcat ctgcagaagc
     2341 agaacctaat ttaggatcgc tcaatggctt gatgacattc ccttggacag gtgcatccac
     2401 tacatcttgc gggatactga taaagctcgc gccttttttt gaactcttag ccatacgata
     2461 agcattggca atcacttctg aaattgtttc tggatcttgg atttctgcac tgtattttgt
     2521 gattggctgg aacagtgctg cattatccat gctttgatgg gtcaacttca atagatcgct
     2581 tcgttttact tgtccggcaa ttgctaaaac tgggtcacct tctgctgtcg ctgttaccaa
     2641 acctgtagct aagttactag caccaggacc acttgttgcg ataactactc ctggctctcc
     2701 tgtaatacgt ccgattgctt gtgccataaa tgcagcattt tgttcgtgac gagtcacgat
     2761 taattcagga ccttgatcct ctaattcatt aaatacacca tcgatttttg cacctggtat
     2821 accgaataca taatcaacat gatgattaat caaactttct actacagatt tcgaaccttg
     2881 tttcattttt tcgtccattg aacatcgtcc tttttatgct ttatttttaa ttattagtta
     2941 gaaataatca caaataattg atacagtttc taaacctgtt tcattcaaaa gtatagcacg
     3001 ttttatttca tttgtttagc catatgtttc aaaaaatgaa aaagaatgac agtttttaca
     3061 taaaaactgt cattcttaat tgaaagtttc aatttataaa gtctacagat ccatagttct
     3121 catcaattta cgattgttga agtaaatcaa accaaatacg atagaaggac ctagtagaat
     3181 acaccattgg ggctttacga aaaagaagag aaacaaactt gtcaatagta aaaaatctag
     3241 taaactcaca taccattttt tcaacgtata gtagaacgct atccgtagaa cttgatttgg
     3301 tttcgacgct ggatttctca cctgaaaata ccagtagttg atgctaaagg aaactgataa
     3361 acaagcaagt aaaacaaaca acggaatcaa ccattttcca taagaaaaac gtataaaaaa
     3421 gaaacaatca aaaatcatta tcacactaac tatccaagca aatagccaat aaaaaaatcc
     3481 ctttagccaa aattggcgaa acgtctttat gaacaaacgt actggtgaaa aacttttttc
     3541 ttttgctaat tcttctgtca tacctatcat cacgatgcaa cctggaccaa taaaaagtaa
     3601 agaaaaaata aaggaaaaga cattccttcc atctatcgac aaaaggaacg cagctgctat
     3661 atacaagata ttgacacacc aaaaacaaag gctacttgcc aatgattgat acaaccaata
     3721 aaagaattcc atataaacat ttttgtcaaa acgctgctct ttcataatca cctcctattc
     3781 cttcattcct gatgaagcga tcccttctac aaaatatttt tgcatcgcta aaaatataaa
     3841 agcaacagga agaacagaaa caactgaggc agccatgatt aatgcgtact ctgcatcaaa
     3901 tagcccaata aacattttca accctaactg gattgtttta ttttccgtag aagacaaata
     3961 aatgaatggc cccatataat cgttccatgt attaacgaat gtgatgatcg tcaaactggc
     4021 aatcgccggt tttgtaagag gtaaaatgat cttgcgatag attccccact ctgataagcc
     4081 atcgatccgc gcactctcac ataaagaatc tgggatacta ctgtagtatt gcttcaacaa
     4141 gaacacacca aaagcattga acgcttgtaa tagcaccaac gaccacaacg tatatgttaa
     4201 acccactttt ctcatcataa tgaactgcgg gatcatataa gactgccaag ggacagcaat
     4261 cgtgccgata tatgctaaaa ataaaatatc gcgcccttta aaatttagtt tagaaaaccc
     4321 gtaagcagca aaactagaag taaacaactg aatcaacgtg atcacaacgc ttaaaaaagc
     4381 tgtattctta aaaaatgtca ctaaaggaat acgagaccaa ataaccagat aattctctaa
     4441 atgccaagtt ttagggatcc attgaatcgg aatcgtgaac acttcattat ttgctttgaa
     4501 tgaagcagaa accatccata aaaaaggaat gatcgtcaat aaagctaata caatcagcag
     4561 aatcataccc aaccattgaa taaagggcat gttttttgaa cgaatttttg ctttttttct
     4621 ttcatttcga acacctccaa agttataatc ttcatttctt tgtaatgatt acaatccaga
     4681 acaacggtta ttatagctga ttcatttccg ttcttcttat gtttgtaagc gcttatttaa
     4741 caagttatgt aaatctcttt attttttttg atttaaaaat gaaaaaatac aaaagcaaga
     4801 ctgtcatacg tctcgctttt gtattgaaat ttcttcgatt agagatactt attactgttc
     4861 aaaagcttct ttgaaacggt gaatcaattc attgactaca ggtgataaaa tccgattctt
     4921 tttccagact agcatgcagt tcgtttcaat cattgggtca agcggaacga atgtcactcg
     4981 ctttgaaaga tgacttacag caccttctat gactaaagca gcacctacct gattctcaat
     5041 tagcgcaaat acattgaaaa tcaaattgta cgttcctgtg atcagcaact gctccttttt
     5101 tatgcctaac cagtcagcaa acattcgctg tatttctgga cgctttgaga tcaaaagagg
     5161 tacattcgca aagtcttctt ttgttatcac gtcttttttt gctaaaacag aattttctaa
     5221 aatgagcaat ccccattttt cctttcttgg taacaaaatc gtttcgtatt tctctgtatc
     5281 tactggatct agcaaaatcg ctaaatctaa caggcttttt tctagtcact ccgtgatatc
     5341 atcacttgtt ccgctgtgga tatgaaattg aacgctggga taatcacgga tcaacttttc
     5401 tagtaatagt gccaatgtat tcgaattatc agcttccaca cagccgatcg taaatcggcc
     5461 gctgaataat tgtttttttc tgttctcgaa ttcttgagtg gtttgattcg ttaaatctaa
     5521 aatttcttct gctcggcttt tttagaaaat aacctgcttc tgtcaagatc attttgcggt
     5581 tttcgcgtac aaacagttct gttcctagtt cctcttctaa ctccttcagt tgtcggctta
     5641 aggttggttg tgtaagatgt agaacttctg cggcttgaga gattgttcct tcttctgcaa
     5701 ttgtccaaaa atattttagt aagcgtaact ccatagcgat gctccttgat ttttttactt
     5761 gatacattcc attttatttc tagataacac acgatcatat ttcttgattt ttccttgtaa
     5821 acgttccaaa cattcttgca tttcagcaat ttttttcgtc aaaagttcac tttcttcaat
     5881 caaaagctta cgccgctcaa atacagttgc ttctccttcg ctagataggc gaatatattc
     5941 aatcaaagac tcgatcgata atccggcatt tcgcatacag atcgtaaagt cgacccattt
     6001 taggtcttct tctgtataat cacggattcc gccttttgtc cgattaactg gtggaatcaa
     6061 cccgattcgt tcataatagc gcaatgtatc ggccgaaatg cccttttctt cactgacttg
     6121 tttgatattc atctgatcac tctttctctt aatttcttgc cactttactt atgtatttta
     6181 tttattctac aactttaagt gtactccaag tcaatactca tttctattaa aactaagctg
     6241 gattatctat atcggttgtt tgtgtattat ttcaaataaa aaagtcttgt ttttttattc
     6301 ttttttggat atacttttaa caatttaggg aaattttagg aaaaggggta taaaaatgac
     6361 aacgtatcag cgaaagttat tattatcgac atcggcggga attgctttag agaatatgga
     6421 tattatgttt ttagcttttt cattatcttc aatgattact tcttttcata ttagtggtac
     6481 gcaagcgggt ttcatttcaa cgatcactaa tttggggatg ctcattggag gtattttttt
     6541 tggcatcata gctgataaat atggacgtgt gaaagtattt tctcaaacgg tccttctgtt
     6601 ttcgattgct tctttattga tgtattttgc ttcaaacatc tacttggttt atctctttcg
     6661 ctttatcgca ggtgtaggag cgggaggaga atacggggcg tgtatgtcct tgatttccga
     6721 aagtttttca aaaaaacaaa ttggacgagc ttcttcggtt gctggtattg gtgcgcaggt
     6781 cggtgcggct ttggctgcga ttttagctgc tgtgatcatt ccaacgtttg gttggaagat
     6841 gttgtatgtc gtaggtgtac tgccggtgtt gatggtcttg ttcattcgtc gcggcttgac
     6901 tgaaccaaag gaattcaaat ctgtacaatc tgccgaaaag aaaaccaaac ttagcagact
     6961 gtttgaatca aaacatcttg cttggcaaac atgtggcctt agtatcatgg taactgtcca
     7021 aattgccggc tattttgggt taatgaattg gctgccttca attatgcaaa atcgattagg
     7081 gctttcggtt tctgggtctt cattgtggat ggtcagtact attttaggca tgtctttggg
     7141 gatgatgact tttggcataa tcatggataa attggggcct aaactagcct tttctttgtt
     7201 tttaatttgt tcatccttat ctgtctatct acttgtgtta gcccatagcc agtggagttt
     7261 ggtagcagcc gctgtgatag tcggctactt tatcaatggc atgtatggtg gatatggcgc
     7321 agtgattagt agtttgtatc caacagaaat ccgcgcgacg gcgaataatt tcattatgaa
     7381 ccttggacga gctgttggtg gtttttcttc tatcgtcatc ggtttcttga tggatcatta
     7441 tagtttaact gccgtaatct tgtttttgag cggtatttac ctagtcagtc tgctggtctt
     7501 gacaactctt actggtgtta cagcattaag ggaaagcttg cagcattgat agttgagtct
     7561 gtaaatgaca agaaagaggt gtggcaaaag cttgcatctg cggtaataag accagccaaa
     7621 tcaaaaacat gagacactgt ttccgtttgg ctggtcgtat tacttgatgc agggcagctt
     7681 tttcaactgc taatttcctt ctatctggcg gctactattc tttgacgtcc gtcatttcaa
     7741 agtactttac taataactta gcataacgaa aaactgtgga tacactcgta tattgagcgt
     7801 ctgcataatc ttccaaattt ttctcaggat gttgatacat gaattcaatc aaatgataat
     7861 tatatgattt tctgtagaaa tgaagataaa taatgtagat tgggaagttc tcctgctttt
     7921 ccatagaaaa gcgccgatta ttctcattct tcaaaatgac cttatcagga tatttttgga
     7981 acaattcttc taaatctgtt agataattca agatagactt acttgatacc ttcaattcgt
     8041 tttgtagttc ttctattgaa caccaacgtt ctgtttcaag cagtaaatga atcattttaa
     8101 ttttcttttg agaaactttt gttaaaaaag tctgcatatt ttctcctcct gtatctactt
     8161 tactatacta catacaagaa aaaaaacgga tacaaatatc atattgtcac accgtcaata
     8221 gtgcataaac ctgttattat ttctcttttt ttcctaagta ttctattgat atgaatcat
//
LOCUS       DADQCX010000106         8272 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.108, whole genome shotgun sequence.
ACCESSION   DADQCX010000106 DADQCX010000000
VERSION     DADQCX010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.108"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(110..994)
                     /locus_tag="J8R83_002400"
     CDS             complement(110..994)
                     /locus_tag="J8R83_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAZ9575515.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1089..1526)
                     /locus_tag="J8R83_002401"
     CDS             complement(1089..1526)
                     /locus_tag="J8R83_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575516.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(1743..2654)
                     /locus_tag="J8R83_002402"
     CDS             complement(1743..2654)
                     /locus_tag="J8R83_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9575517.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(3111..3539)
                     /locus_tag="J8R83_002403"
     CDS             complement(3111..3539)
                     /locus_tag="J8R83_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575518.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(3567..4205)
                     /locus_tag="J8R83_002404"
     CDS             complement(3567..4205)
                     /locus_tag="J8R83_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575519.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(4209..6245)
                     /locus_tag="J8R83_002405"
     CDS             complement(4209..6245)
                     /locus_tag="J8R83_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAZ9575520.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            6371..7036
                     /locus_tag="J8R83_002406"
     CDS             6371..7036
                     /locus_tag="J8R83_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575521.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT         2653 a         1553 c         1253 g         2813 t
ORIGIN      
        1 gtaaatttct tttttgtaca aaaaaaaggc tgtgacaaaa gtcttgtcac agtcccttat
       61 cccgaacaag cggtgttctc ccgccaactc ctcggtcaca acctccattt taacaataaa
      121 cctgtaaatg tgagggcaat actttgattg tcacaggtaa tttatcccct tcatctccat
      181 caacattcgt cgtcaattct tcctcatcag ctaatgacac aactaattgc tcacaagtaa
      241 ggtaggctag atttttcgta gattcatcta ctccttttaa taggtctggc aatgttttaa
      301 gcgtatcgat caaagaagaa tcttttaaat aaaccaaatg gagcttacca tcatccactt
      361 ttgcatttgg aagtaatgtt tcaaaaccgc cgactgagtt agttagtcct atcagcaagg
      421 tactgctctc aatttcttcc ttctttccat caacttctac gtgaaacgag taggattgtg
      481 tggaagctaa ctgtttgatt cctgacatga aataagctag ttttccaaat ttcgtcttct
      541 tctccgcatc tacatcattg attgattcag ggatagagcc aattgcgacg acattcataa
      601 aatagtcgtc atttattttt ccaatatcca atggcttgac tgattcaatc gaaaaatgat
      661 tgatcgcttc ctcaggttct agcggtatcc ctaatgctcg agccaagtca ttcaccgtac
      721 ccaatgggaa aaatccgaaa tttggccgat gttcttgttc agcgattcca ctgattcctt
      781 cgttgactgt tccatctccg cccatgacaa acacactatg atacccttcc gtagccgctt
      841 cgcgagtaaa gttttttgca tcccctgctt tttttgtatg caagacgacc acttcatcaa
      901 acaccgattc caattttgct atcgctaatt gctcaaattc ctttgcttgt tcaccgcctg
      961 aactggggtt taccactaat aaaacttttt tcatcacttt ctttcccttc tgattgattt
     1021 ctttaatata acgatagcat aaagaaaaaa attaggctgt gatgaagtac tgttcatgaa
     1081 acattcattt attttttgac aagataaaac atccatacta tgaaactgag gaaaattaaa
     1141 acaatgatat aggaaataaa agaaaatgat aggcattgta tacctaataa agtaaaaatc
     1201 ttaggtggca gataaaaaca caaaaatagc aagagaatgt aatagcgttt cttccacttt
     1261 ttgttatcag accttatagc gatcagagga ataccaaatg cataactgaa aaactcttga
     1321 tgtactgtta atatgtcacg gccttgaata ataaatgcga caatccccgc tataattagt
     1381 gtgcctaaca ccaaaacgga aaattgatga atatatttta tatacaaatg atccattgta
     1441 cttcctgcct ttttatttgt gagaaaaaca aatccgtata cgtgaataac ttctagaaat
     1501 aaaagaaatt tgcaaaacca ctccatttat ctacttctac gtgcattttt tgatattgtt
     1561 ttctttattt aagattatac agaaaaatat ctagggtcgc tggattctaa gtaaaaaaaa
     1621 tttttaaaat aaaaagaact aaatcaagta gtaattaaac tactgttgat ttagttctaa
     1681 taaaaagatt tagatgaaca gttttattga tttaaatagt tcatattttt tatttatacc
     1741 gcttatttac tacttgctgt actagaatct gaagtgaatg tactcaaaac attttcaaag
     1801 tctttgtctt tgatttttac attagcgtct ttcaatactt cgccaattac tttattctgg
     1861 aaggtactgt cacttaattt tgtgtctgtt gcaatttctt tcaattcttt tttgtattta
     1921 tccatgtcgt tgcctttgtt ttggtttttc accattttaa ccacataata ttccgtagta
     1981 taagttgaag cattggtaga agtgatcaca tcagaaactt gaccatcttt caacttaaag
     2041 gctgcttctt tgacttctgc cggaaccgtt gtagtagtgg aatcaaattt cacttttccg
     2101 ccatcttctt ttgtcgtagt atcagttgac ttgtctttgg ctaatttaga gaaatcgtct
     2161 cccttatcag cagctttctt cacatctttt gcatcatctt cacttgctac ttggataatt
     2221 tgagcttcca cttctggatg gaaagattcc caagccgttt ttaaatcttc atcggtcaat
     2281 ttgatatgtt tctttagacc ttcttgaaag gctagacttt gtttgatact gtctttgaat
     2341 gtttgttctg tgtaacctgc agatttcaat tgtgaatcaa atgaatcacc caattgtttc
     2401 tttgtttgat catattgaga atcgatttct ttggttgata cgtcatctcc atatttatct
     2461 tcaaatactt gataaacgat caactgttgc acagcggaat ctgctccttg catttttttc
     2521 aagctatcca ttacttcttg ttcgctgatt gtaccgcctt tataactaac ggctgttttt
     2581 tcaccggcat tcgtacagcc tgacaataag ccagtgccta gtacgatggc aagtgctaaa
     2641 aatctttttt tcatttatca attctcctac ttttcgtttt ttgcgaattg ctaaaaacaa
     2701 aggtgttcaa gatgaaaatc atcaagaaca cctttactaa tctgctcgat acgtcctgaa
     2761 tagatataag gctacacaat ccagaaagtt cgctcagcag aataaatgtc aagtagcaca
     2821 tcacacctta atatactact tcttttgtta ccgtttttca agtctatctt gcgttccgta
     2881 tttaacgtaa ctaattctta gaacaaatgt tatcgatttt gtttttcttc ttccgctgct
     2941 gggatattca aatcagacac ttttatgttc gattttccag acattttttt gttgttttta
     3001 ttatgatata tttttataca actaaaaatg aatatattaa aactaccaaa aataactttt
     3061 aacgctgttt cattatatgt tttttctatt ttatataaac ttttggatac ttaataccaa
     3121 ccggttggat tgtaccaaca tgagaatgtg tcagttctat ttcctgtcgc acttgcatag
     3181 gcccatactc cttttgttgc atttgctgat cgaatagagt ttccaacttt cgcttttgca
     3241 ccgtgacgat tatagacacg actatagtgg ttagaatgac ctgtttttct cgtacaagtt
     3301 gtatcactat aataaaccca tcttccagag ctatgattaa ttgctgttct agaaatttcc
     3361 cggtctactg gtaaatttga cttaataata ttacctttag catcaaaatg aatctctcct
     3421 ggctttaaag atttgtaata gatttcaccg tgaactgaat ttgcttccac ttcagatgac
     3481 atagcgtttc ctccaacaaa acctatccct agtgcacaaa taataactgc ttttttcata
     3541 aaacgacatc ctttcctttt tgatttttaa agcatgatct tcttgtttcc tattttggtc
     3601 agatatggat catgcgtgac tacgataact aacgtacctt gggaagcttg ttgcgataag
     3661 atttcaacta ctttatcctt atttctttta tccaatgacc cagtcggttc atcggctaaa
     3721 atgattttgc tattcttcaa taagactctc gcacaggcga ttctttgctt ctcaccacca
     3781 gataatgtgt agataggcgt acttagcttc ttgtttatat ttactttttt caatgcctca
     3841 tactttgctg ttcgcttatc tgaaacattt aaattcgaaa acttcaatcc aatatctaaa
     3901 ttaaaatcga ttgtttcata ttcaatcaac ccaaaatctt gaaaaagaaa agatatggta
     3961 tttcttttta tcaagcgctt ctctctccca gttaattgtt tcgtctcttg atcgaacaaa
     4021 tagaattgtc ctgaactgaa ctgatcattc aatcctaata tattcaataa cgtactttta
     4081 cctgctccac tttctccaac aacagtcaca agatccccag catccgcagt gaaacgatcc
     4141 aaatgaagaa tcgttttgtt tcgaatgatt tttttcgcac cttttatcac tatcaacggc
     4201 tccaattgtt aacctccatt catcagcaat aactgacttt tcttttctgt agacaaaata
     4261 aaaacaactg aaagaataaa atcaatgaag ctaaagaaaa aaatattaaa aagatattta
     4321 ggctctcttt ctataagaaa aaggaagatt acacttgtcg ttccccattt gatgaggttc
     4381 atcatgaaga aatctttata cgtttcaaag agcgaataac cacttgaacg aaagatagcg
     4441 attttccgac aattgtagac aaaatatatg cataacatga catagctcaa caagaagaaa
     4501 gaaaagaaag tgagtaaaaa tatctgtatc aagtaatgaa atgatctgct taacactttg
     4561 acagctatct cttcagtctg agtatacgga aatgataact gcaagttatc acgtaactga
     4621 ctttcttcaa tcagctcaaa taacctttct ttcgacaaag agcctatctt gatctttaac
     4681 ggtggataga tttctccgct gagaatattt ctttccaaat acatactgtt tttcaatgtc
     4741 agtatttcaa caaccggata atgttcgatc caggggatag aaggaataaa tgtataaatg
     4801 ggttgattgt tttttataaa tagaaatttc ggttcttttt cactgatttc ttgataatat
     4861 tctgttattt gcgccaggtc attttttaaa tctgtatgtc tatatcgttc agggatcaat
     4921 ataacagggt gcgtttcttt ttcggttatt tggatcaacc ttccagagac atcaatcaaa
     4981 ggaaatttct taagataatt cagatttatt tttatccctc tgccaaactg ttcattttct
     5041 tcattcaagt aatctgatac attgactaat atacttccgt ttttattcaa agtttcatat
     5101 aattcctgat ctgctgctga tgcaaaacga ttggaataaa taaaatccac gtggtttttc
     5161 ccgatggtta ctggataaaa tacatgatag tcctcaccag cgatttcttt tggtggttca
     5221 tgggaaacag ctaactgtga agaagaaaaa acgatagttg ctaattcgac attggcaacg
     5281 gtcaaaagaa gagaaaacaa caatccaaat gtaaaaagaa tgtattggat atagttgaac
     5341 gcttctctta acgaagcgat tttttcaact aataaaagag aaatcaaaga gataccatat
     5401 attccgctga acaagaaaac gtacatctgg aacaaataaa gaaattgctc cttataatac
     5461 ataaaaataa aaccaccaat gattcctgca attatgaatg taataatgat tttctttttc
     5521 cccaataaac accacaatac ttgatgtaat gaaaagtcat tattcaacaa taaactgatt
     5581 tctttattca tcaataagaa aaaggatgat aacaaaagga ataaaagaat caatccaata
     5641 gttaaataca ctcgataatt atatacgtct gtatttgaaa taaccgaata cgaatagcta
     5701 ttttcaaagt cttcaaaaat attagtggca taatcagtgt gaaatgcttg attgaatcga
     5761 tcagtgaata gtgaaatgaa ccgttcatag gcttcttttt ctctcgtcat caagaaaaat
     5821 tcaccttcaa aatcttttat tttgatcgat tcttcaatgg acgttacgcg aaaggaggta
     5881 ttagaatagg gtaccttctc gtgagaagat ttgacatccc cttgataata caatgtcatt
     5941 tcaagctttg gctgtatctt gaagttccaa gatgtatcta cttcattgga ttcatttact
     6001 gtttttttca tataagaaag ctcagtttct gatgagacat tttcaaatac catgattagc
     6061 tgctcatatt cttcttgccc aataaaatgt tgtggcaatc gaatcggagt ataagtatct
     6121 gtttgatgga aaaattcatt tgtccgatag agtacctgtt tatttatact aaccaaggca
     6181 aaaccactca tgataccggt cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt
     6241 atcaccactc tcccttactt aaatgattct ttgataaaat cataccgttt ttcatcaaaa
     6301 aaacgtatct atcaagtgta taggtcatgt agaataaatc tatatactgt agaatcgaaa
     6361 ggagaagaag atgaacaccg gagaaaaaat acgaacttac cgcagaaatt gtaagcttac
     6421 gcaaaaagaa ttaggcgaaa aaattggtgt ttccgataaa acgatttcta gttgggaaaa
     6481 ttctcgtaca atgccagacc ttgaaatgct gtcactttta catcatactt taggtctgcc
     6541 gattgatttt ccttctattg aatcagctac cgaatcaata gaaccaacat tgccagatga
     6601 acctcttgtt aacaagaaat cttattcatc aaaacaaccc ttctcactca aaaagacact
     6661 atctttcttt ctgctcgtct tttgtttggt ctatcttttt cttatcaatt atcaatacaa
     6721 aaatgaaacg atcgatcgat tcaatccttt tttgaaacca caaatcggct ataccacact
     6781 ccctgtagga tacgtggaca attccatcga acgttgggta tgtaatgata tctttggcca
     6841 tggtacatgg ctgtcttttc acgctggaga ggtagaaaaa gagaaaaacc atgctgtaat
     6901 caaacacaaa ggaaaacacg tcatgaacgt tcgcctgctc acttgggaag ccattccctc
     6961 agattaccaa gaaatcctca gccaagacta tgacgacgcc ttaaaaagaa gccctcagga
     7021 gccagatagg cattaagtag gagatgaacg tagagataga aaaaatcaat gcacatgatc
     7081 ttatccaaaa aacaggggta caaattaatt gaaaaagcct tgagatgaaa gttcctaaat
     7141 aaaaaagttc agaatgatag gtatttctgg cttatagtat aatatttacg ccacagcctc
     7201 ccaatgattc tttttggaat cataatcaag gatggacatt cacaaaaata ttttgctcat
     7261 tcgatccgaa tagattaacg accaatctag taagtaatat agattggtac gtagtcaagc
     7321 tgcacataat ttagatcaat tttagttctt ttttatattt ctatgatctg ctcatttact
     7381 tttatatgat ggcttacagt aacataaata aatatgataa tcgctggtag tttatccaag
     7441 agtactcaat aaaatacaaa atggattgtt caagcgccta tcataatgat aaaatgaaac
     7501 aaataaacga tacaaggagg aagagacttt gagtaatggc agaacaattt tttcattgta
     7561 aaaattgttc agttgttaat ctatgggatt tcggtagcat gggcattttt ttatagagga
     7621 atcacaccaa cctggccgtt ttatctcttg ttagtgggaa tattagtagg aaattttgcc
     7681 cctcttcact atcgtacgaa cttttttcca actgattctg gcctttttct taaaacaaag
     7741 acgcgaaaat tagaaaacat tattgaaatg acaattacct gtataatcat tttcttagtt
     7801 atattcctaa acgtcttcta ataagaatct cttaaaatta gcttgttaca gttagttacc
     7861 tagtttatat aacacagtta tcttatcttc cttatcaaca tcttttgcca actctttgtc
     7921 ttaaattcga aacatataag cagagctacg aacaccaaga ctgtttcggc tctgtttttt
     7981 gcatcaaatt cactcttata tagctgataa tctcggctct ttaaaagaaa ttattttcgc
     8041 ttcattttat tataaaaagg ctaggaacct tgatgttatc aggttcctag cctttattta
     8101 agtattaccc cacagaccct tccatataga tttttaaatt acacactagt ttaaactaaa
     8161 acaaacaagg aaacacttac catttaatca taaaattagc tcatatgaat atattagaat
     8221 gtaaaataga ctggtcaaaa tctggtcaaa aaagaggact aatacaggta gt
//
LOCUS       DADQCX010000107         8228 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.109, whole genome shotgun sequence.
ACCESSION   DADQCX010000107 DADQCX010000000
VERSION     DADQCX010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.109"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="J8R83_002407"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="J8R83_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAZ9575522.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="J8R83_002408"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="J8R83_002408"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAZ9575523.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="J8R83_002409"
     CDS             2591..3376
                     /locus_tag="J8R83_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9575524.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="J8R83_002410"
     CDS             3389..4240
                     /locus_tag="J8R83_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAZ9575525.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="J8R83_002411"
     CDS             complement(4364..4816)
                     /locus_tag="J8R83_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575526.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="J8R83_002412"
     CDS             complement(5281..5649)
                     /locus_tag="J8R83_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAZ9575527.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="J8R83_002413"
     CDS             5799..6281
                     /locus_tag="J8R83_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAZ9575528.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="J8R83_002414"
     CDS             6318..7328
                     /locus_tag="J8R83_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAZ9575529.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="J8R83_002415"
     CDS             complement(7443..8156)
                     /locus_tag="J8R83_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575530.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DADQCX010000108         7904 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.110, whole genome shotgun sequence.
ACCESSION   DADQCX010000108 DADQCX010000000
VERSION     DADQCX010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.110"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(13..2184)
                     /gene="copB"
                     /locus_tag="J8R83_002416"
     CDS             complement(13..2184)
                     /gene="copB"
                     /locus_tag="J8R83_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAZ9575531.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2204..4390)
                     /locus_tag="J8R83_002417"
     CDS             complement(2204..4390)
                     /locus_tag="J8R83_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAZ9575532.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4390..4599)
                     /gene="copZ"
                     /locus_tag="J8R83_002418"
     CDS             complement(4390..4599)
                     /gene="copZ"
                     /locus_tag="J8R83_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAZ9575533.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4612..5052)
                     /locus_tag="J8R83_002419"
     CDS             complement(4612..5052)
                     /locus_tag="J8R83_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAZ9575534.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5126..5665)
                     /locus_tag="J8R83_002420"
     CDS             complement(5126..5665)
                     /locus_tag="J8R83_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HAZ9575535.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6280..7746)
                     /locus_tag="J8R83_002421"
     CDS             complement(6280..7746)
                     /locus_tag="J8R83_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9575536.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         2147 a         1735 c         1375 g         2647 t
ORIGIN      
        1 cttttttcat tattatttga ttttcaatgt caaagcattt agagctacaa ctaccgtact
       61 taacgacatc aagacagcac caactgctgg acttaatatg ataccaattg gcgcaagaat
      121 tccggctgct agcggaattg caagaatatt gtaacctgcc ccccaccaga ggttctggat
      181 cattttcttt cgcgtttgct tggctagatc aagaaaatgc aaaatatctt ttggatcgct
      241 gtttgtcaat acgacatccg cagaatcgat tgcgatatct gtccctgcac cgattgccat
      301 cccgattgaa gcacgggcta aacttggcgc atcattgatc ccatcaccca ccatgattac
      361 ttttttccct tggtcaaggt atttctggac aacagcttct ttatcatctg gtaataaacc
      421 gccataatat tcttcgatcc ctaaataatc tgctactgct tgggcagcgt ttttattgtc
      481 accagtaagc atgacaggag tgatttttct ttctttcaat gttcggataa attcttttgc
      541 ttctgttttt actacgtcac ctaaagcaac gattgcagct agatgatttt ctaaaatcag
      601 gaagctgatg gtatttcctt gttcttggta aggtttcaat aatgcttgtt ctacgtttaa
      661 tccgagacgc tcaacttctt tttcattaac tattttcact tgttgttttt tgactgttgc
      721 ctctagcccg actcctgaaa gattttttag attttcagct tgataaggct tgatttcatg
      781 ttctttcaaa taattcataa tgccaacagc caatggatga ttggcattcg cttccaaggc
      841 tcctagatat tgaaggattt catttttatt gaacgcatca tcaagtactt cgacacccgt
      901 tacagtaaat tttccttctg ttagtgttcc tgttttgtcc agcatgatca catctagatc
      961 attggcttgc tccagtgcat tgcggttttt caaaagtaat ccgtttttag ctgctattga
     1021 tgtggagcga gcaacaacta atgggatagc taaacctaga gcatgaggac aggcgatgat
     1081 aaagactgtt accatacgtt ctaatgcatt aggaagatct gtcaagaaca accaggcgat
     1141 gaatgccagg atacccacaa ttaatgcgac ataaaacagc cattttgcca ctttgtcaga
     1201 taatgactct agcttggatt tttctccttg tgcttttcgc accatttcca taaccttcgc
     1261 tagataacca ttttcaccag ttccagttac ttcgatttcg atcgttccat ccccattgat
     1321 agaaccgcca atcactttgt cattggcttg ttttttgatt cctcttgatt cgccagtcac
     1381 agctgattcg tcaacaattg tttcaccttt caagattaca ccatctgttg gcattttatc
     1441 accagaccgg acgatcaaac gatcaccttc gtttacttct ttcaatgaaa ctgtctcttc
     1501 ttttccatct ttcgtcaagc gtttcactga ttctggcagt aattctgcta gtttttgtaa
     1561 agcattgctg gcattcgaca cagcattcat ttcaatccag tgacctagta gcataataac
     1621 gatcaaagta gccaattccc agaagaaatc catgacgtgt gtatgtggat tgagcagatt
     1681 tgcgataaac gaatagacac tataaatata tgcaactgta atccccatcg cgatcagtgt
     1741 catcatagca ggactttttt gtttcaattc catcttagct ccacttaaaa atggctgacc
     1801 gccatagata aatagtatag ttgctaagat caatacgagc caatcagaac caggaaacgt
     1861 tacttgaaat ggaaattcca ttcccatcat tggtgaaaaa agaatgattg ggatagctag
     1921 gataagcgat agccaaaatt tttgtttgaa attccccatg tgcatggaat gatccatgcc
     1981 gccgtgttcg tgatccatgt gcatcgaatg gtccatttgt ttgctgtttg ctatatctcc
     2041 atggttatgt cccatgtgca tggaatgatc catctgacta tggtcatgtt tcatctccat
     2101 ctgtttttca tgagattctg tactttcttt gtttactact tcttttttat gctcatgttt
     2161 tttctccata tcgttcccat tcatttttac tccatccctt ctcttacttt ttcatgtgtc
     2221 gatttaagct cagggagttc aacaatacac tgacggaact aaacgccatc gctcctcctg
     2281 caatgattgg attcaaaaag cctagtgcgg caaaaggaat accaatcgta ttatagacaa
     2341 aagcccagaa aagattttgt ttgatttttc tcaatgtcaa cctagacaac tcgattgttt
     2401 gtgcaatgga tgccaaactg ctattcatca gcgtcacatc ggctgtttcc atcgcaatgt
     2461 ccgttccact tcccattgcc ataccgacat cagctaatgc taaggccggt gcatcattga
     2521 ttccatcgcc tgccataccg acttttttgc catctttctg aagtttttct acgtaggctg
     2581 ctttatcctc tggaagtact tcagcaaaga tatgctttgg atcaatacca acttgtttac
     2641 caatcgtttc ggctgccagt ttgttgtctc ctgtcagcat aaaaacatct aatcctttat
     2701 tctggagctg cttgattgct tgtttggctt ctagtttgat ttgatcagcc acggcaatcc
     2761 acccgatcac ttgcttttca tcagctaaaa acatgactgt ttttccctgc tgttctaatt
     2821 ctaacgcgtg ttcttggtat tcatcaaatg ataggttcaa ttcaattaat cgtttacgtg
     2881 tacccgcaaa atagcgtact ccattaatcg taccgctgat cccagcacct gggtgggctg
     2941 taaaatcaat catatcgtat gttgctgctt cttgcagttt tccgtattcc acgattgctt
     3001 tacctagtgg atgttcagaa gcttgttcta aagtataaaa aatagatagg acttcttttg
     3061 aaccgactag atctgtaact ttgggctttc cttctgtaat cgttccagtt ttatccaaaa
     3121 caatgctgtc taagtgagca gctgcttcta atgcttctcc gcctttaatt aaaattccat
     3181 ttcgtgcacc aacacccgtt cctaccataa tagctgttgg ggtcgctaaa cctaatgcac
     3241 atggacacgc aatgactaat acagagacac tatggatcaa tgcgagttgc caatcaccag
     3301 tgatcaaacc tgtagctatg agcgtgataa acgcgatgac taatacgatc ggaacaaaaa
     3361 tccctgagat ccgatctgcg attttttgga ttggggcttt gctcccttga gcatcttcca
     3421 ccatttgaat gatttgcgct aatactgtct gcttgccgac ttgtgtgact tccatgtgta
     3481 gcagaccatt cgtattgatt gtcccgccaa aaagcgtgtc atccggattc ttttctacag
     3541 gaagattttc accagtaagc atactttcat ctatcgcact gcttcctgaa ataattcgac
     3601 catctgctgg aatctgctca ccaggacgga tgactagttg atcaccaacg actacttctt
     3661 caatcgctaa cgtttcttct ttcccgtttc ttatcacttg ggcggttttt gtttgaagag
     3721 acatcaattg tttgattgca ttacctgttt tcgtttttgc tgtatgttcc aaatatttgc
     3781 cgagcaaaat cagcgtgatg atcatactgc tgctttcaaa ataaagatct tgggggtgtc
     3841 cacggaaaaa tccgttgtaa atgctcaatg caaaggcagc cgatgttcca attgctacca
     3901 atacatccat atttggtgct ttcgtcttga ttgcatggta cgcaccttta taaaaacgag
     3961 caccgacata aaattggaca ggagcagaca gcactaactg gacgattgga aaatgaaaaa
     4021 agtgaacaat cgccgcatgg cttcctaaca tcatagcaat cattgacaac atcaacggca
     4081 aagtcaaaac cgtactcaat ataagatcga atagcatttt tttcaaatac gcttgctttt
     4141 cttctgcaat tttttgtttg tgggcttcat cgtacaaaat tgcaccataa ccgatgtttt
     4201 ctacgctttg gattaatttt tcagtggtcg tcccttcata tttgacactt gctttttcag
     4261 tggccaagtt gactgtggca ttgaccacac caggttgtcc gttcagctct ttttcgatcc
     4321 tagcagaaca atttgcacaa gtcatacctg taatgacgaa cgtatccatt ttggtttctg
     4381 ctgttgccat caaatcacct ctgctttata acccaatcca ttgattgctt gacaaatctt
     4441 ttcggattga acttttgttt catcaaactt gaccgtaccg tttgcttttt tcaaatttac
     4501 tttcactttt tgcacgccgt caagtgcgct tactgtttct tctactcttg ctgcacaatg
     4561 attgcagctc ataccttcga ttgaaaattg ttgtttcatt ttttcttcct cctattgatg
     4621 ttgtttacat tcacattgac ctgggataca gttacattcg atcgtatcta ctggttgctt
     4681 ttgttccagt tgtttcaaaa tctcattgat atcttcttga gtcaaagtgg cttcttctac
     4741 tagatccgca atcgtctctc caatcctttt tgcacagata tgggaaaaaa gattttccgt
     4801 cgcactgcga actgtttcca tctccgagac agctggatga taaatgaatt tttttccttc
     4861 ttgttctgtc cagatcactt ctttttttac caaacgtccc agcaaagttt tgatcgttgc
     4921 tggtttccaa tccatcgaat cagctaagat ctgcgtgatt tcttgggctg tcgtctgtcc
     4981 aagtgtccaa ataacacgca tgatctccca ctctgaatca ctgatcttta ctggcgtttt
     5041 gactttttcc atttatttca cacctttcgt ttacaaatgt aatcattagc ttatgaatac
     5101 agattacgct tgtaaacaaa aactgtcaat tatttttgct ctctattttc aatttagtta
     5161 aaaattcttg tttctctcgt cttgttttaa ggatgatcag tttatttctt gcattagcta
     5221 cttggatcag ctgctgtatt ttcggttcat tgttttcttc aaaatgccag ataaaagata
     5281 aaaattctaa gtattccctg tttagtttct ctgaaaatga ttcaggcata tctggccgag
     5341 attttttgtt tatctttctt tttagagaac gccaaactac tcggtagatg gcgagataac
     5401 gcggcacttt aagccaaatg atcttatctg cttctttaat cctttcctct aatgtagaag
     5461 tataatttcc ttcaacaatc catgacggat tagataccat aaacgattgc tgttcttgca
     5521 aaaaccactt ttttgcctga atactgtagt ctgttgtatg ccataaaagg tctagcggca
     5581 gtagcggaaa gtcggtgatt tctttgatct tccttgcgag ggtcgatttt cccgacccac
     5641 tttgtccaat cacgatgatc ttcattcttc tccctcactt ctctttggaa tttggttcga
     5701 tcataccact tataacgccg caaaaaaaca agggactgtg acaaaagtcg tgtcaaagtc
     5761 ccttgtttcg aataaatggt gttcaatcag ctgaccttca gcattaactc aaaaaacggc
     5821 aaaatatgag gagctatttt ttcgtttgtt cctctaatac tcaggtcaaa tcgctgattt
     5881 tacaacctct tccttaaacg gtgttctcct gccaacacct cggtcacaag gcacaatagt
     5941 caacaaacat gagaagttgt tttttgaaat tgctccttgt gactcggagt taaacggcag
     6001 gctcactacc tctttcttaa acggtgttca aaagcttgca tctgcggtaa taagcccagc
     6061 aaaacgaaaa atatgagggg ctatttttgt ttggctgttc ttattacttg atgcaggaca
     6121 gctttttcac aacctctgat tcacggtgtt ccagaagtag cttctgcgaa aaacaagccg
     6181 aaacttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc ttgaagctga
     6241 ccacttctgt cacaacctct tgtaacaagt atttctattt taaggctgaa ccactgtttc
     6301 tggttcagtg atttctttgt ttttgtctcg acgagcaatt gctggcaaga tcatacctaa
     6361 taagatcaag acaattggtg tgatgatatt cgtgaataat tggaaccacc atgctttagg
     6421 atcagcagta taatctactt ttggcaccat tcctaggata catgcaaacg cagtgaaggc
     6481 aaagcaccaa gcaccaaaga taaaaccgat ttttggattt ttaacaaatt tatattcaga
     6541 attgaatttc ttataagctt tattcaacat catatatgcc aagaacaccc ataggtaacg
     6601 cattggcatg acaactgagt tcaagttcgt caaccatttt actaattcat tcatatcttt
     6661 gataccaaag atcggcaaca aaataatgat tcctactagt atacctgtca gaagataacc
     6721 attcaccaat gtacctttac gattacgttt acgtagccag tttggtacaa attctggatc
     6781 cgcatctgct aacaagattt ttagtggtgc atcaattgaa aaggctaatg cggagatttg
     6841 tccaatcatg tttgtcaatg cgtaaatgat catcaatgag ttaccgatac catagtaatt
     6901 acctaaaatt tgaaaagcac tgtatgcccc atttgccatc aagtctttag gaatattatc
     6961 gctagcaaac agcataccca ttgcgactga gcctaataca gcacaaatcc ctaccattgc
     7021 tgctaagaag atcatccctt taggaaattc ctttgcagga tttcttgtag agttgacata
     7081 aggggatatt ttttccgctc ctccaactgc aaatactagc atcgaaacgg ttgtgaaata
     7141 actgaaatca aatgttggaa tatatgtttt cacttgattc atatgtggtg tggcaaattc
     7201 catcgttgga ttgatgaacg gtgccgttac agctaaaaga ataaataaga tcgacatgac
     7261 gaacatcgct gttccggcca gtccgccaat cactttcaaa gtagaaagtc cttttgttga
     7321 taaatataaa aaggcaagaa atataataag tgaaataact gctaccattt gtactgacat
     7381 cgtatttacg atatttccat ttccttggac tgcccaaccg ccagcaatca ggattgcttg
     7441 aggcttttgt gccaaataag gaatatggac gacccagtaa gtccaagcgg catagtatgc
     7501 cagtcgttta ttagatgtcg tattttcgac ccatgaactg acgcctcctt tactatcctt
     7561 gaaggctgac cctaattgtc caacgatcaa tgcgtatgga ataaaataaa tggccaaaat
     7621 caatagccaa gaggtgacaa ctgatactcc ttgctgagca tagttattaa ctacattccc
     7681 catgccccaa accatgttaa atgcaattaa cgcaacagta aaccagcgta attgtttgtt
     7741 gttcattcgt tctctccttt atgataaaaa tttgttatcc agatgtaatc atattcaatt
     7801 tttaacaaac ttacaagaca gtgttatttt atgtgtgtat tcttttattt aatacacatc
     7861 gttttttcat attttttcca tcaaaaaaat aagttatttt cttt
//
LOCUS       DADQCX010000109         7700 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.112, whole genome shotgun sequence.
ACCESSION   DADQCX010000109 DADQCX010000000
VERSION     DADQCX010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.112"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            545..1108
                     /locus_tag="J8R83_002422"
     CDS             545..1108
                     /locus_tag="J8R83_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575537.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1387..1674)
                     /locus_tag="J8R83_002423"
     CDS             complement(1387..1674)
                     /locus_tag="J8R83_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9575538.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPNLLCGTHENFYEQLKKIR"
     gene            complement(1664..1993)
                     /locus_tag="J8R83_002424"
     CDS             complement(1664..1993)
                     /locus_tag="J8R83_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9575539.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2298..2627
                     /locus_tag="J8R83_002425"
     CDS             2298..2627
                     /locus_tag="J8R83_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575540.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2914..3399)
                     /gene="vanZ"
                     /locus_tag="J8R83_002426"
     CDS             complement(2914..3399)
                     /gene="vanZ"
                     /locus_tag="J8R83_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAZ9575541.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3552..4463)
                     /locus_tag="J8R83_002427"
     CDS             complement(3552..4463)
                     /locus_tag="J8R83_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAZ9575542.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4891..5499)
                     /locus_tag="J8R83_002428"
     CDS             complement(4891..5499)
                     /locus_tag="J8R83_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAZ9575543.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5505..6536)
                     /gene="vanA"
                     /locus_tag="J8R83_002429"
     CDS             complement(5505..6536)
                     /gene="vanA"
                     /locus_tag="J8R83_002429"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAZ9575544.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6529..7497)
                     /locus_tag="J8R83_002430"
     CDS             complement(6529..7497)
                     /locus_tag="J8R83_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAZ9575545.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2350 a         1532 c         1282 g         2536 t
ORIGIN      
        1 gttaaaactt ttttagcaga ttttaaagtt tcgtcaaaac taatatattc tggtagctga
       61 gcattcaaat agctttcaga cttcagaaga aaattacgag catttttata gtccatctct
      121 aataaagtta ttcttttttt atccaataca ttcagctcaa ttccttataa tattctattc
      181 cttagtatct caacattatt tactttataa aacgaataaa ttttgtagtt ctaattcaaa
      241 tattgcatgt tatatctaat atgggagcat tttataattt tcattgtgat aaactcgtta
      301 ttaactttag gatacactag ttaggattaa attaggtatc tagaaattta cttaagattt
      361 ttttgtttat ttcgtataca cactcgtatc aaaaacaatc gattatgaga caaaatgaaa
      421 tgacctcttt tattaaataa aagaggtcat attttgtatc ataacttgtt gcattaacta
      481 tgtatctata actccctttt atgatacaat caagccagaa ttaaagtacg aaaggaagaa
      541 aagcatgagt ggatacattt atggttatgc ccgagtgagt acacgttcac aagaactaaa
      601 tcgtcaatta gacttactca atgaacaaaa ttgtaatgaa atcctaactg agaaaatgac
      661 gggaaccaaa gcggttcgtc cccaactaaa tcgtttaaaa gataaaattc gtccgggaga
      721 tacggtaatt gtagaaagtt tttctcgatt gggtcgtagt acaaaggatt tgattgacct
      781 tgttacctat tttgaagaac accatgttaa gctggtgagc ttgaaagaaa acttcgatac
      841 cagcacgcct cacggacgct taatgatgac tgtcttccaa gcatttagtc agttcgaacg
      901 tgatttaatt gttgaacgta ccaaagaagg tttgaaaagt gcacgtgcga gaggtcgtaa
      961 aggtggccgt ccacgagtga accagaaaga tgttgatcga gcagtaaaat tgtataaaag
     1021 tcaggtttat agcgtaaaag aaattacgga aatgactggt attagcaagg caacactcta
     1081 ccgctactta aaagacaata gggaataatc tattttaatc tttaggaatc tataatattt
     1141 atgggagaat tagagtgatt tttttattat tactaaaaaa caatataaaa taacgcattt
     1201 taagccctct ttgtgcataa ggatgaagct tttaatttga aagaggctta aaatgcgttt
     1261 taattttttc tatttttcat aaatatatag gttagtggtt taaaattata gggtattaca
     1321 actctcagct gttaaaaatt atcttttaaa gtgtcgtcta tcctctcaag ttgaaacatt
     1381 gggttcttac ctaatctttt ttaattgttc ataaaaattt tcatgcgttc cacatagtaa
     1441 gttaggtatc actgcattat ctttaatttc atatgcaacg cgatatgtcg tacctgcata
     1501 cttgaatcca atagcccaaa ttcctgataa atcacccgtt ttttgttctc ccgaatgagg
     1561 acgaactgct atctcatcat aaattatcgt taaaaattgt tcttttaatg ttttctcttt
     1621 taattttttt agatacttta ttacgtgttt agaaggtaga atctcataag ccaatttctg
     1681 ctgccaactc ctcttttgtc atcggtttag aatttgcaac agtatcttca gcaatagatt
     1741 taaatgcaga agttaacgca ttttttctat ttctaaattc ttttaagatc tcttgtttgc
     1801 tataaccttc tgaaagaata tcagccaaaa tatcttcact aaaatcaaaa aattcttttt
     1861 taggctctac aaactcataa aggataccat tctctacaag cttagcttct acttcaacac
     1921 cattgggcac atcgaattct ttagggaccg ttaacataat agaatttcct tgttttcttg
     1981 tttttgtaat catattattt cctccattat tttacatttc gtaattactt agtaattaca
     2041 ttgtacgcta tttttagtag aaatacaaaa taataaaact cctttagaac aattttcaaa
     2101 ggagttttat ttgattagga aattatgtag aataataata tgtttttaac ttggaatcaa
     2161 aaacgcactt gcaagtaagt ttacttcaat acatgaaatt gcttataata gtgtattgga
     2221 attaaggtag attgacaaaa gagtgatcaa ataggtatac ttcattcaaa taatcgtttg
     2281 aatgtgaggt gagatgaatg aaaaaagttt gccaagtgac tgtcgtacat aaagaaaaag
     2341 taaatggaat aaaaaataaa ttggatcaaa aagatttttc aaacttactt gtgttaggga
     2401 aatgtttcag cgatttttct agaattaaaa ttttctatgc tttagaaacc tataaggaaa
     2461 tgtgcgtctg tgatttagca gaaatactta ctgctagtgt cgctacaacg tcacaccatt
     2521 tacgtttttt aaaaaaacat ggaatggcaa aatcacgtca agatggaaaa gtagtttatt
     2581 actctttagc gaatgaagac atcctttccg ctattcgtgt tttttaaagt tatcagaaaa
     2641 tctatctatg aaatcttagt ttgggggtac cgtcaggaaa atgcggattt acaacgttaa
     2701 ggaaatttat taaagagacc aattcctcag cactaaaatt gataattggg ctttctttgt
     2761 tactatagtg ttaggtaagc tttttacttt atcaccggtt ttcccctcac ttcacaccta
     2821 cgggcgagtt tccccacatc ccgttttcca tctaatccaa ttcattcaat atctttatgt
     2881 gtatgaaaga tcagattgct tgatttagac atcttacacg taatttattc ttaaatgggt
     2941 acggtaaacg agcaataata cgagcaaaag tatacctaca aaaataataa ctctgtctaa
     3001 ttttttttga ttcatatgct tattgcttaa accatataat ttcagtccaa gaaagcctcc
     3061 aacagtattt gtaattacat ctgttatgtc tgtcgctcca atagcgaaga taaattgaat
     3121 tatttcaaaa gtaagactta aaaccagtac aaaagcaaac ttaggtaaaa atccgatttc
     3181 tttaaaattg acattcaaaa gcaagccaaa tggaataaag attataacat tatctatcat
     3241 ctctctgaaa ttcccagtag cagtaaatgg agtcaagtta agacttcttt gatgataatt
     3301 aaatactgat aaaatattgt attgtaattt gaataacact aaccagatta gtgtcactaa
     3361 atataaagct agcaatcctc tagataatat ttttcccaat ataatttcct ctaattcttt
     3421 tgtttaagtt gtatcattag tatagcaatg tcctagttaa cgtgggtttt aaattaaaaa
     3481 gctaacgtta ccccaaaagt gctagtacaa taatgctgtt cattaatttc gttggtttca
     3541 ttccgccatc cttacctcct tgaattagta tgtgttgatc cgggaaacac tgtcacaatt
     3601 acaccgtcta tattgtttcc tgatatctca taacgaagat tagtcggcac atgaatggtg
     3661 gtatttttag taacaggata ataaaagatc tcatattttt ccccatttac actaacagaa
     3721 atggtttttt cttcttttag gtaatccata tattcctcga gaacgaaatt cttttctttc
     3781 ataatcgcac tatgtggtaa accaacatag cgaatatgcc atggttcata ttgaattcct
     3841 gttaactctg ttttgtcctc tggataacgt aaaatgaacc cgtatttcca agcattttct
     3901 tctatccact ttccttcagg ggctcgttcc attttcgtca agcttgatcc tacatctagt
     3961 gataaacctg aattatgctc actataacct gctggtaagg catactcagc ccccatttct
     4021 tggtaaagca cactttgctc atcaaagtct cgatagccac tattaataat aaaatgacta
     4081 acgccaccct ttacagcatc attgaccatc tctgaaaatt tttgtgctat ttcttttgac
     4141 atataaatat tactatcaag caacccgtat ccatttatta attcgtcatg tttagataaa
     4201 ttcacgatat ctgacttcac actttcttgg cgaacaggat atttactatt gattaatagc
     4261 agatttcctt gataaacctg ttcttctgta attgttttct cttgggtatt ttcagaagtc
     4321 ccactatttt ctaaatgttc tttgggattt tgatcataat tttgaaattc gactttttcc
     4381 tgagaaaaca gtgcttcatt aacgtagtca taacctaagt atattaagaa taacaataac
     4441 aataaaaaaa acaacttctt cattttcagt ctcctcctta actatatagt tggaagtatg
     4501 aaatatttct agaatcttcc ccttaaacgg cacaatctcg tttgagattg tgccgttttg
     4561 ccccgtaaat tacagtcaat tatttcgccc tactggattt actattatca ccaatgtaga
     4621 tgaattttca taagtgatac ccatgctgaa tttaacgagg ctgaactgcc tgttgacaat
     4681 gggcggtgtg aaataccacc cctctatgcg atcagtctta ttatcaggct atcttgccgc
     4741 agcgcacgca gataatgacc gcaatatcgc tctgccttac atcttcaata ctatctacta
     4801 tatataaatt ccctaagaac cagttacata cgtcgggttt cctgccgaaa gagttagctt
     4861 atatagtttg tccgtgcaac ggttaaaagt ttatttaacg gggaaatcaa aatagctatt
     4921 ggggtatggt tcgtctctta atacatagtg ccaccattcg aggctatatg cttcaaaccc
     4981 actgttttcc atgatggagc gcaaacgtct gcgattttgc gcttcattgc atgatattcc
     5041 atttgccgca tgatgagagc gttcatccat aaaatcaaat cggctcccca ttggtacaag
     5101 ctcacccgtg tctaatcgat aaagcgtaag atcaatggca ctgccgcggc tatggcttga
     5161 ttttgaagcc acgtatcctt ttgaaatcat ctcagttcgg tcaatattgg gataataact
     5221 ttcctttgtc aggttatttt ccggctgtgc agcccattgc ataaaacagt ttacagcacg
     5281 attaggacgg taaccgtccc atagaagcaa tccgtaccct tgggtagcag ccagttcttt
     5341 tgccttcaaa agcgattcag ccaactcgta tgtccctaca atgcgattta cttcataacc
     5401 gtcaaccggt tttccggtga aattatccca agtggcatat ttagcgtccc aacgaacacc
     5461 gtgtactatt tcatctaaaa aagtaaatcc tatttccatg cttatcaccc ctttaacgct
     5521 aatacgatca agcggtcaat cagttcggga agtgcaatac ctgcagcggc catcatacgg
     5581 ggataacgac tgtatgacgt gaaaccgggc agagtattga cttcgttcag tacaatgcgg
     5641 ccgttatctt gtaaaaacat atccacacgg gctagacctc tacagccgag cgctttatat
     5701 attttttttg ccgtttcctg tatccgtcct cgctcctctg ctgaaaggtc tgcgggaacg
     5761 gttataactg cgttttcaga gcctttttcc ggctcgactt cctgatgaat acgaaagatt
     5821 ccgtactgca gcctgatttg gtccacctcg ccaacagcta acgcggcact gtttcccaat
     5881 accgcacaac cgacctcaca gcccgaaaca gcctgctcaa ttaagatttt gctgtcatat
     5941 tgtcttgccg attcaattgc gtagtccaat tcgtccgcgc tattgacttt tttcacaccg
     6001 aaggatgagc ctgaacgcgc cggcttaaca aaaacaggat aggtaaacgt agctgccacc
     6061 ggcctatcat ctttattaat aacccaaaag gcgggagtag ctatcccagc atttttcgca
     6121 acgatgtatg tcaacgattt gtccatacaa attgctgagc tttgaatatc gcagcctaca
     6181 aaagggatac cggacaattc aaacagacct tgtatggatc catcttcacc tgacttgcca
     6241 tgcaaagctg aaaatgctac atcaacatgg ttgatttcat attcatggtt ctttttaaca
     6301 agtaatccgt gcattttttt atccggcgag agtacagctg aatagcaatt gtcgttttcc
     6361 cattccgcgc aaggtttttc gcacattttc catacaccag atttcgtaat tccaatgtat
     6421 aacggctcgt atttttcttt attaatgtta gcggctatct ctattgcaga ttttaccgat
     6481 acgtcatgct cctctgagca acccccaaac agtattgcaa cttttattct attcatgctc
     6541 ctgtctcctt tcaaaatcca aacagttttt aatggttttt tcaacggtat cacgcaacgc
     6601 ttgctcggta taataggccg tatgcggtgt gattatcacg ttaggcattc tttgaagttt
     6661 aagtaaaaat tgattatcaa ttggtttttg ggtgcaatca gagtagaaaa actcttcctc
     6721 tccttccaat acatccaatg cggcaccgcc cagtttcccg ttttctaatg ctttaaccaa
     6781 ctcataggta tctacaagtg gaccgcgccc agtattgata agaaatgctc cttgcttcat
     6841 tctctgtatt tgttcgtggc tgataatata gtgcgtatcc gtattgagcg gcacatgaag
     6901 cgtaacgata tcgctatttt gcagcaactc atcaaacggt acatagttta cctctatact
     6961 tcggctgcga ctataagcca acactttaca tccaaatcct cgcagccgct caataaccgc
     7021 tttgcctatc tggcccgttc ccaccacacc aactgtcatg tcgctgagta ccttgccacg
     7081 gtcgctgtcc aacctgaaat catgtttttc cacagagcgc acaatcgatt ttacgttgcg
     7141 tactgccata agaattagca tcatagtata atcggcaacg ctatccggcg agtacgccac
     7201 attgtcgaca gtgatgccca ttctcttagc agcagttgta tctatatgat tgcagccgat
     7261 gcttcgggta gaaatatatt tcacaccggc tctcttcagc gcaagaagaa tagaggcgga
     7321 aatctctgat ttatgtccca cactgataca ttgattgaaa ggcgcggatt tggcgttgga
     7381 ttccgacacg ttggcgttaa ttatcgttgc cataacgcca aagcgaggcg aaagagcatg
     7441 gaatgcatct gcctcatcct gctcacatcc ataaacagta atgccgatgt tattcataat
     7501 taagaccaac cctttctgtg aaaggcacca aataaaacgg ggatgccaat ggtaatcttg
     7561 tcaaatcttt ctctgaagaa cgaaaacggc tcgttcttac ggtattaagt ctaccgtgta
     7621 agaacgagcc gtttcttaat attaaattgt taatttccta agaaaaagta aagataacct
     7681 tgagattttc ctaaaaaatt
//
LOCUS       DADQCX010000110         7692 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.113, whole genome shotgun sequence.
ACCESSION   DADQCX010000110 DADQCX010000000
VERSION     DADQCX010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.113"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..690)
                     /locus_tag="J8R83_002431"
     CDS             complement(<1..690)
                     /locus_tag="J8R83_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9575546.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKS"
     gene            complement(810..1457)
                     /gene="eda"
                     /locus_tag="J8R83_002432"
     CDS             complement(810..1457)
                     /gene="eda"
                     /locus_tag="J8R83_002432"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAZ9575547.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(1541..2968)
                     /gene="uxaC"
                     /locus_tag="J8R83_002433"
     CDS             complement(1541..2968)
                     /gene="uxaC"
                     /locus_tag="J8R83_002433"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAZ9575548.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(3042..4121)
                     /gene="uxuA"
                     /locus_tag="J8R83_002434"
     CDS             complement(3042..4121)
                     /gene="uxuA"
                     /locus_tag="J8R83_002434"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAZ9575549.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(4124..5755)
                     /locus_tag="J8R83_002435"
     CDS             complement(4124..5755)
                     /locus_tag="J8R83_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAZ9575550.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            6059..6730
                     /locus_tag="J8R83_002436"
     CDS             6059..6730
                     /locus_tag="J8R83_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9575551.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(7455..7692)
                     /locus_tag="J8R83_002437"
                     /pseudo
     CDS             complement(7455..7692)
                     /locus_tag="J8R83_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2493 a         1498 c         1041 g         2660 t
ORIGIN      
        1 agattttaac aatgaaactt tgtattgaga ttggtcaatt cttactcgtt cagtagttag
       61 tttataacat attaaataac aaataagtgc acatatcgaa aatattcccg caacaattgt
      121 aaaagttgat ccaccacgaa ctatttgagc gcctgaatca tctcttgtat aaataaataa
      181 tggtgttaat acaccaatga ccaaacttgc taaagtagct ccaacatttc ggaatgtcga
      241 tagcattgtt ctttcttctg taatagaagt aatagctgat gccattgatc cataaggaat
      301 atttatagat gtgtaaaaaa tactccccca taatatatac gtaacataca tgtatactac
      361 cttaacgctc atagaagctg aaatcataga agtttgatac attaaaaaac ttgctaaagc
      421 gactggacca ctcattctta aaatccacgg tttaaactta ccctgcttag ttgctttcga
      481 tctatcaaca atacgcccca tagttacatc agtaactgca tcgataaatc ttgctactaa
      541 aaataatgtt ccaacggcag ctccgcttat ccccaatact tttgtataaa agatcattaa
      601 aaaagaacta gcaaaaatga aagtaaaatc gtttccaaaa tctccaaaca tatatcctat
      661 tttgtctctt ataccaaatt ttctttccat acaattctct cccttctgtt gttaagcgtt
      721 ttcattctga tgaaagtacg tactatactc tgaagcgtaa agagtcagta tttatttttt
      781 acatttcaga gtattatttg ttttttctcc taataattct ttatctcata aaacttatct
      841 atatatttac tagctactcg acttacttct tcaaaatcac ctttttcaac agaagccaat
      901 aaattcccac ctacaccaac tgcaacaact cctacttcaa accaatcttc taagttctct
      961 atacttactc cgccagtagg cattatattt acgtgtggta atggagcttg ataggctttt
     1021 acaatggatg gaccaaaagc agaacctggg aatagtttaa tgatatctac gccagcagta
     1081 agtgcctcct ttatctcagt aattgtcata caacctggta aataaggaat ttgatataaa
     1141 ttacaaatct cagctgtttg tcgatcaaaa gatggactaa cgatatattc tgccccagcc
     1201 ataattgcga tacgagcagt aaacgcatct aaaaccgtac cggctccgat tattacatct
     1261 ttttgatcag catatttttt agcaatttct ttgattattt cttcagcatt aggaactgta
     1321 aaagttagtt caatcccttt aattccaccc gcaataattg aatttattgc tttaatggcc
     1381 tcatccttat ttttcccacg tacaaccgca atgactccag ccgcttctaa cttacttaaa
     1441 atttctactt ttttcatatc tatctccttc ctttatggat acatactttg tctagctgta
     1501 ctaacttaca aagaataaat ttaagctttt atttcaagta ttattttcta cttccgattt
     1561 caaaaaaatt aaaataatta tacgcattac gataacaaat attctccact atctgactaa
     1621 gatacatttc atcatctgga attcggcctg ctttaaccca ctcgcttagt aattgacata
     1681 atactcgacg aaaatactca tggcgaggat agcttagaaa acttcgagaa tcagtcaaca
     1741 tacctgtaaa attcgacaac aaactttgtt gtgccatcgt agtcaactgt tgacgcattc
     1801 cttcagctgt atcattgaac caccaagcac atcccaattg gattttttga atcatacccc
     1861 cttggaagct ttgcattgct gttgctagtg gaagccaatc agttggattt aatgaatata
     1921 aaattgtttt tggtaagcac ccactctttt cagcggtatc gaacaatgct acaacatttt
     1981 gtgtcaaact agcttgatcc cccatcgaat caccaccgac atctactcca atttgttcct
     2041 ttaatatact tgaattattt cttaaagcat ttaaatgcat ttgcatcgtc caaccatatc
     2101 ttgtatactc agacatcaaa tgtaattgaa tacctgtaac aaattgtgca atttctgata
     2161 aatggaaatc cgtttttcct gctaaagctt ttattaacag attgtcgagt attttttcat
     2221 ctgctatttc ataaaaataa gtattcaaac cgtgatctgc taatcgacag ccaatttgat
     2281 gaaaatgatc cactcgttgg ctcaatgctt gcttcaaccc attaaagtct ttgattggta
     2341 tagccgctgt ttgactaagt tttaaaatat agttcgaaaa gcctgatgat ttgatactcc
     2401 agaccttatc tggacggaaa gtaggtaata ccttgaaaga attatcctgt ttagaaagct
     2461 cagtatgata ccacaagtca tctgtaggat catccgttgt acagatggct ttcacatcca
     2521 tcatctccaa caattctttc gggcgatagg aatccgtttg aattttttcg ttagcacgtc
     2581 gccaaatttc tggtgcattc ttctcagaaa ttgtcaaatc aatatcaaag taacgttgta
     2641 attccaaatg agaccattca aaaataggat tacctggcgc cttctccact gtttttacaa
     2701 aagctaaaaa tttttcataa tcatcacctg gaccactgat caactcttct tctataccat
     2761 tagctcgcat caatcgccat ttataatgat ctccagctcc tttatcattt aaccatacct
     2821 gagtcaaatt cttgtattgc ttattttcta gcaaatatgc tgggtctaaa tgacaatgat
     2881 agtcgataat tggttggtgt tttgcaaatt tatgaaaaag tcttttagct atttcattct
     2941 ctaataaaaa gttcttatct aaaaacatat ttaaacactc ctttccttcc gttagttttt
     3001 agaagagaaa atttttcctc taaataaact cccttatata attatttact cgcccccttt
     3061 tcaagcgctt cccaaatacc atttaaataa actgcaccta gagctcggtc atataatcca
     3121 taaccaggtc taccggtttc tccccaaatc atccgaccat gatctggacg aatatagcca
     3181 ttaaatccat tatcgtacat tgtttttaat atcttataca tatctagaga accatattct
     3241 gatttatgcg gcgcttcgta aaaatcgagt ccattgtcac ttaaatattt gatattacga
     3301 acatgtgcaa aaggaatccg atcccgttga caaaattcag atagaatttc atagacatca
     3361 ttatctggtc gttctgcaat acttccagta cataatgtaa taccattaga aggagaatcc
     3421 actacattac acaaccaatc taaatcgtca cgatttttaa caatacgagg taatccgaaa
     3481 atggaatatg gtggatcatc tgggtgaact gccattttaa tcccaacttc ttcacatgtc
     3541 gggataattg ctttgagaaa atatgcaaag ttctctcgta atttctcttc atcaacttct
     3601 ttataggctt ctaataattg cttaatttgt gataaccgat gaggttccca acccggcaat
     3661 tcaaaattat tagtagaatt ttctacttct ctaataattt cctccggatc agtagggata
     3721 ttttttgaaa tataggctaa cgtagaagac ccatcatcta aacgataatc caaatccgat
     3781 tttacccaat caaatactgg cataaaatta taacagataa cctcaatccc aaattctgcc
     3841 aaattgcgaa tcgtctgttt ataattctca atgtattgat ctcgtgttgg taaaccaatt
     3901 ttgatatcat catgaacatt aacactctca ataactttca aggtaagtcc attggcttcg
     3961 acttcatctt ttaaagattt aattcgttct ctcggccaaa cctctccggc tggtatatcc
     4021 attaatgttc caacaattcc tttcattgct gggatctgac gaatttcttg tagtgagatt
     4081 ttttcttcat ttgccccata ccatctaaaa gtcatttcca tagttacttt cctccaactt
     4141 ctgttatata tttattgatt gttttacgaa ctgcttgagg acctactagc atttcgcaaa
     4201 agattttttc agttttcttt cctaccccaa cttgatataa atctaaacca aagatttctt
     4261 tattttctaa aatttcctgt accgcacaat gaatctttga aggatcttgt tcacctaatt
     4321 tcaatactga taatttatcc tgcaactcta ccaataacgg atcaggactt ggcacaaaat
     4381 tttccccttg atcatcgact gccagtaaat aacgtaacca agcagcaata gcgataggaa
     4441 taaatgttag attttctgca tttccgtctt tttcgacata ctttttaatt gtttcaccat
     4501 agcgaatcgc tactttttga gaagtatctg ttgcaattcg ttgtggtgta tctggaatat
     4561 agggattagg caaacgttta ttaattactt catcaataaa ttgttttgga tcaataatgc
     4621 ctggattttc aactactggt aaaccttcta aataacctat tcctttgatt aaaccaacca
     4681 aatcatcatc ctgcatctct gctgaaattg attgatatcc tagcagacaa cctgttactg
     4741 ccaaagcagt atgaagtgga ttcaagcttg tcgtaacctt catgatgtct gctttatcaa
     4801 ccgtctctct atctgtcata atcacaccag ccttttccaa tttaggccgg ccatttggaa
     4861 aactatcttc aataactaaa taatgaacta cctcagtatt agtgaaagca gcaatattgg
     4921 tatgtttttt tgtgtgaatg atatctaaat cctcgagccc catcatcaat agatcttcct
     4981 ttacattctc tgaaggattt ggcgtaattc gatcaatcat actccaagga aaagtcactt
     5041 tttctttatc ctttaaataa gcaataaatt tttcagaaac atatccttct ttttgccaag
     5101 cttctgcaat cgtaaaaata ctatcttgaa aacgttgacc attctgtgag aaattatcag
     5161 tagaaaccat cgcaatcggc aactctccag cattaaatct gctatataac aaggatgtta
     5221 caatactcat cgtatgttga ggattgctag gtccagattt gatatcagct ttgactaccg
     5281 aaaagaattg ccctttagaa tcttttaaac tgtaaccttt ttcagtaata gtaaacgttg
     5341 taaactgtaa tttaggatct tcaaaatatt taaccactct ttgatagtcc gctatattct
     5401 tcggattgca atataaacta tcagccgtta ctgccaaaag tctttttttg agttcaccat
     5461 ctccactcat aacaatttcc aaaatgtcat tgttatagtc atgataagct ttttccacta
     5521 cttcttcatc aaatgtttca cacacaacta ctcctgtttc taattcattt tgatctgcta
     5581 agcattgagc aatttctgca tgaaatcctc gataaagatt tcctccacca aaatgaagcc
     5641 atactggatg ttgctggcct tcttgcttaa cttctttgac atcaaaacac ggcagtagaa
     5701 tctgcatttc attgaattct tcgatagaat tttgccaatt tttaatcgaa accataatta
     5761 acctcctcaa actgatatgt tagttttgat acattttata ttttaaaacc cattgtaacc
     5821 gttgtcaata taaaaaggga ataaacttgc ttttttctac catatcagaa tgattgtatt
     5881 ttttattcag aaaaataaaa tactccttct ttttggactg attttatcga aacttatttt
     5941 ttcttttttt catgtattct tttattttta taactagtgt attacttcaa aatttgatat
     6001 tatatggcat gaacagaatt aaaatatcag ttaaaataaa agttaaggag cattgtgtat
     6061 gacaattaaa actagtctcc aaaatcaagc ttaccaatct attcgccgac aaattatcta
     6121 tgctgactta gaacctggaa aaaaagtatc agaaaaaaaa ttagaagaaa cactttctat
     6181 tggtcgtaca ccaatacgtg aagcactgat tcaactccga caacaaggtc ttgttgatac
     6241 aattcctcaa agcggaaatt atatctcatt aattgattta gattcggcca aaaatgctcg
     6301 atttgtcaga gaacatttgg aacgacaaat tatgttagag tgttgtgcca aaatgaataa
     6361 ccaaaaaaaa cggattttag aaactataat ttcagaacaa gaaaaagctg ttagtcaaaa
     6421 aaatgctcgt agtttttttc ataatgataa tttattccat aaagcttgtt ttgaaattgc
     6481 agagcgagaa gaagtatggc aatggttaga aaataacaat acacacttag aacgatttcg
     6541 atggctacga gtaaaaacgg aaggattaaa gtgggaaaaa attatggaac aacattatca
     6601 actatttgag gcattaacaa aacaagatcc agaagaagct aactttctaa catcgttgca
     6661 tcttcattta atgcttaatg agcaaaatat tgttttagct actcatccaa aatatttcaa
     6721 aaatatataa cttttaactc tttttaaatt aaatggttgt tctgatcaga aaaatatcgc
     6781 ttgttttctt attatgtaat atatttcata aactattctg cataacaact attgtttgta
     6841 ctttttacat tggataacta attatgactg ctgataactt ttgatattaa actagtatct
     6901 ccaatacaaa taaaaaatag atatcttgtt catcaaaatt agttcgtgga tacttacctt
     6961 catttacatc attcagcggt ttcccatttt cttttattct attatttcat tttctaatag
     7021 acttggcttc atttcgcaat actttttttc aataggcatc aaattggtgt tgtttagata
     7081 tttagttgta gttttgtgac atgataagta tgctcctttt tctcttttcc actaatacaa
     7141 cgatcaaagg gtgctttttt caaaaaacta gaaaaatcaa aataagattc gtattttgat
     7201 tctatatatc ctgtttcaac tacatcttat atttcacaat agaataaata gccttttgca
     7261 tagctgctta acttataaga aattgcaatt tacttcttca aagtgaaaac gaatatgagt
     7321 aaaataaaat tattcttctt acagataatt aaaaatagcg cgtaacaaaa atcggcattc
     7381 aatcacataa ttaggattga tgccgattac ttatattcta cgtatagttt tagtattctt
     7441 attttttatc accagtaacc aattgagaac agccctaaag cagaatagtc ttttatctca
     7501 aaacgcttaa tttcaggctt aggaatatga ataatctttt gagtatattc tttctctttt
     7561 aatcttactg aagaaatacc actgcctatc ttttttacaa atatttcatt tggtgtacag
     7621 actaataaaa caatatttgt aatcaatcct tgcactaaag aattaaaagg aagactattt
     7681 aaaacagggt gt
//
LOCUS       DADQCX010000111         7629 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.114, whole genome shotgun sequence.
ACCESSION   DADQCX010000111 DADQCX010000000
VERSION     DADQCX010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.114"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(16..708)
                     /locus_tag="J8R83_002438"
     CDS             complement(16..708)
                     /locus_tag="J8R83_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9575552.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            793..969
                     /locus_tag="J8R83_002439"
                     /pseudo
     CDS             793..969
                     /locus_tag="J8R83_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1145..1714)
                     /locus_tag="J8R83_002440"
     CDS             complement(1145..1714)
                     /locus_tag="J8R83_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9575553.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="J8R83_002441"
     CDS             complement(1788..2111)
                     /locus_tag="J8R83_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575554.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="J8R83_002442"
     CDS             complement(2265..3077)
                     /locus_tag="J8R83_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575555.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3431..4279
                     /locus_tag="J8R83_002443"
     CDS             3431..4279
                     /locus_tag="J8R83_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAZ9575556.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4424..5365
                     /locus_tag="J8R83_002444"
     CDS             4424..5365
                     /locus_tag="J8R83_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAZ9575557.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="J8R83_002445"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="J8R83_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1372 g         2472 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 aacttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggtttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgagaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg aatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccaaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcatataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctcgaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaaccttt
//
LOCUS       DADQCX010000112         7617 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.115, whole genome shotgun sequence.
ACCESSION   DADQCX010000112 DADQCX010000000
VERSION     DADQCX010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.115"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..2305
                     /locus_tag="J8R83_002446"
     CDS             <1..2305
                     /locus_tag="J8R83_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9575558.1"
                     /translation="NKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFTFLGSLSSI
                     YVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQLIDPTEKEI
                     TAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVAVNGSMSAD
                     KTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNTIDSVTPNA
                     DKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKGNVSNFPTY
                     QAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVTGYSFAQTN
                     GSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQDLTTNTPTI
                     NGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKTNATVSINA
                     NGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNEKGVEVTAP
                     TEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGSKTYDGKAG
                     VPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTNSGIDKVKA
                     ANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVTGVVLGESL
                     DYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPSTGGIGLLP
                     FVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2431..2760
                     /locus_tag="J8R83_002447"
     CDS             2431..2760
                     /locus_tag="J8R83_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAZ9575559.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            2823..3803
                     /locus_tag="J8R83_002448"
     CDS             2823..3803
                     /locus_tag="J8R83_002448"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAZ9575560.1"
                     /translation="MDDHPLVSKERTKNTCCTHITKTVENKQTDFADGDKVPYLITVT
                     IPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFVLSDSGKDL
                     SSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQFVKVDRQT
                     KQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHGLSFGSYEL
                     VEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTPVQMQTNGP
                     SNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK"
     gene            3800..5229
                     /locus_tag="J8R83_002449"
                     /pseudo
     CDS             3800..5229
                     /locus_tag="J8R83_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            5435..6607
                     /locus_tag="J8R83_002450"
     CDS             5435..6607
                     /locus_tag="J8R83_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9575561.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6769..7224)
                     /locus_tag="J8R83_002451"
     CDS             complement(6769..7224)
                     /locus_tag="J8R83_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575562.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
BASE COUNT         2570 a         1440 c         1514 g         2093 t
ORIGIN      
        1 aaataaaatc caacgtatat gtcaaaaaca ttttgtttct agactcaaag ctgtatctaa
       61 aagaaaatac ttacatccca ttatgatttc gatcatcttg atttttactt tcttagggag
      121 cttatcaagt atttatgtaa acgtttatac agaaacgtca aattttgcta accaaacgac
      181 agaggagaca aatagtccac cctattctga aatacagtcc atagaaagca ccaatcagtc
      241 tagcaacaac gagacaacct caaccacatc ctcgactcaa ctgattgatc cgacagaaaa
      301 agaaatcaca gcagcaaaag cagcagggga gaaagcttat tcagaaacag gtagaagcca
      361 gacatttagt actgttgcgg ccactgcgaa tttcaacgga cataccatac cagatggata
      421 tacagtgata tatgccaaag atggagtcat tgttgcggtt aacggatcga tgagtgcgga
      481 taaaactgcg ttacaaggcg taaccaaagc aatcgctttt attgataacc gtccagatat
      541 ccataatctg tttattggct ccacagtaaa tggtactact atcacattcc caaaaagtat
      601 ctatatgggg gtggctaccg ctggaaatac gatcgattca gttacaccca atgcggataa
      661 aagttattct tttacaccct caacatgggg agggcttcct gccggaggag gtatgagtac
      721 tttttcaatc ggtatacagt tagcaaatga tattccattc acggggtact cgatcaaaaa
      781 tgggcagatc gttgatggta agggaaatgt ttcaaatttt ccaacctatc aagcagcaac
      841 ggttcaggtc aatgcgaatc ggacaggaac tttttcttat acagtcaatg gtggagcagc
      901 aaaaatcgga acgtacggga ctacattatc tggaatccat gtgggtgaca aagtggttat
      961 cactccaaca gcagtaacgg gctattcttt tgcacaaaca aacggttctt tcacagccct
     1021 agaaagtaac gtcgatacgg tgacctatac aggcaaacaa acaccaatca ctattaagta
     1081 tcaagactat tttggacaga tgattgctcc ttctaaaata atgaatctta cttacggaag
     1141 tgctgcacaa gacctgacga ctaatacgcc tactatcaac ggatatacct ttacagctgt
     1201 ttcagcgaca gaaacaaaga accaatcagc aatgagtgtt ttagctagtt tagatacaaa
     1261 tggaaatgta atcgtaaagg acgcaaatgg aaaacagatt tctgaagtca tcctatatta
     1321 taagacaaat gcaacagtat caatcaatgc aaatggcagt aagtactatg atggtctttc
     1381 tgttgtaccg atcgttaaat atgcctttaa tgataaaaca gaatcaacat cccttttaaa
     1441 caatgatctc agtattgatc aaatcacatg gaatccaact gatttcaaag cgatgaatga
     1501 aaagggagtt gaagtaactg cgcctactga aattggaacc tatacgtctt ggcaattgac
     1561 aaaaagcgga ctagctaaac tagctgccag aacaaactat ttatttacta tcgtgcagac
     1621 atctgatgtc tatacgatta agcaaatcag cggtgcggta gagctcagtg gcagtaagac
     1681 atatgatgga aaagcaggtg tcccgtcaat ccatgtcaag ctagcagagg gtgtcactag
     1741 ttcgcttact ccagtacaag tggcacttag cagtatggat tacacagcag atgcacaatc
     1801 agcaaaaaat atggttaatg ctggcagcta tacaattaaa ctaacgaata gcggaataga
     1861 caaagtcaaa gcagcaaatc ccaagttgtc atttactgat atagccaaca catcaggaac
     1921 ttataccatc tataaagcta acgcagtgat tactgtcgat gacgctgcct ttaattatga
     1981 tgcccaaagt cactcgattt cggttggaaa tctccacgtt accggtgttg tcttaggcga
     2041 atcattggat tataccctaa cagttaacag ccggacagat attggatcac aaatagtaac
     2101 gattagttta ggcgaaggaa gtgtaaacaa taattatacg attatcgcaa cagataccgc
     2161 taagttgacg atcaatccga ctctcttgct tccttcgaca ggtgggatag gtctactgcc
     2221 ctttgtcttt ttaggactga tctttatttt ttctggcttc ttttatttta tccatcgtaa
     2281 gaaaaaagca ggtgaacagc gatgaaaaaa acaaaaaatg tacgtgtgga tatatttgct
     2341 gttctctttt ttatcctact ggtctttttt ataggttctc cgactgtgtc agctagagaa
     2401 tcacctatta catttacttt gcataatcga atgttcgaaa gcgataagat gccaagtatc
     2461 agtcaaaacg acggaataaa tatcccggat aactttcaag gagtaaaagg gttgaacggc
     2521 gttactttcg ctatatatga tgtctcggat gaattttaca agctgcggtc agaaggaagt
     2581 agtgtggaag acgcacaaag aaaactagca caaaaaagtg atagtgaaaa aatactggca
     2641 gaaaatgtga caaaaacagt agacgaggaa gagggcattg cttcttttag tgcatcggac
     2701 aaagatgagc aaggtcgtga cgctgtttac cgatttgcgg aaataaagac ttcagattaa
     2761 gtaaaagaaa aatcagcacc atttgtcgtt gtgcttcctg tgacagattc atctaatcat
     2821 aaattgacga ccatccactt gtatccaaag agcgaacaaa aaatacctgc tgcactcaca
     2881 taacaaaaac agtagagaat aagcagacag attttgcaga tggggataaa gttccttatc
     2941 tcatcaccgt aacaattcct gagaacatca acgagatagg aacctatacg atcaaagata
     3001 cagctgatcc tcagttatgg ctagaaccag aaacgatcga ttttttgatt ggtggagaca
     3061 agattcatac atttcacaca caaaaaacaa aacatggttt tgtcttatca gattctggaa
     3121 aagatcttag ttcgtttgct gggaaaaaat taacgatccg ttaccaaatg acattgaaag
     3181 aaaacagtga aaaaacgaca tttgataacg atgtacgttt gacgactgac aatcaaacag
     3241 tagaaacaca tcttgccatc caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa
     3301 cgaaacaaaa actagcagat gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc
     3361 aagaaaacgg gataaatcat tgggtagcca aagatgattc aagagcaacg atttttactt
     3421 ccagtaaaga tggaacattt tctgtccatg gattgtcttt tggaagttac gaactagtgg
     3481 agattaaacc gcctaaagga tatatattga gtcaatcaac cattctcttt gaagttgaaa
     3541 aaggcagtta tgatccgctt catcctatac cattggaaat catcaacgaa ccaaaagcaa
     3601 atccgacgaa taatggaaaa acgccagttc agatgcagac aaatggtcca tcaaatgaaa
     3661 aaaatggagg aagctttcca aaaacaagcg aagagatgct tggaggtttc tcaattttag
     3721 ggttgttgct agtcctttca acagggacag cttggtttta taaaaaacaa caaaaaggaa
     3781 acaataggag ggaaataaaa tgaaaaacat caaaacaaaa atatggacgt ttttaggaac
     3841 tgctatcatg ctgcttcctt tcgttctcgg cctaggaact gcagaggttt ctaggccgta
     3901 tcacctacac cagaaaatgt tacggttaat ttgcataaat tgaaattcac ttcagcacca
     3961 gaaaatcaaa taaacaacgg aacggaattg acatttccga atagcgaacc gttgaacggc
     4021 gttgaattca acgtatatga catcactgct acgtactatc caagtaaaga cacagcagtt
     4081 ccagcagacg ctacaccctt cgcaagtgta acgacttctg gtgaaggatt agctaacctg
     4141 actcttccag gtaaatctga tgggaaagat gctgtatacg tctttgtaga aacaccaaag
     4201 cccggtgtcg aaacgtcgcc aaatatcgtg ttaagcttac ccttttataa cccgaattca
     4261 tcagaccctg acaaaccttt agacacgatt cacctatatg ctaaaaatgt catcaaagaa
     4321 agcaatatca aaatccagaa agctgggaac ttttcagggg tagataagtt agcaggggcg
     4381 caattccaga tcaaaaattc agagaatcaa ttcgtgaccg gttttgatga aaacactggt
     4441 gtcgctctct atgatcctgc tgagtcagcg ttgacattca caactgatac tgaaggatcc
     4501 atcagtgtca atggattaat agacggcaat tatactttag ttgaaacaaa agcaccagat
     4561 ggttatcaat taaccaatcc acaaaaagaa actactttta tagtaaaaaa cggaaaattg
     4621 caacaaacaa ccggtatcat ccatggcgca gatgaagcca atcttgggaa tccaaacggt
     4681 gtagtcaatc gggaaaatac aactacggat aacacgatta ctgtagaaaa tgtccaaaac
     4741 tacggtgatt tccacttcat caaacaagat gtgaacacgc aagaaaaatt agccgatgca
     4801 gaattttcta ttctaagagc aaaagatcca actgttaaat taatgaaaaa aatagcaaat
     4861 cttgcctcag gagaataccc atatgcttgg tcagatgaag tcacaggttc tgactgggaa
     4921 gaagtgaaat tgatttctga ttcagaaggg aaattttcaa tcgaagggct gaaacaaggg
     4981 gcatactgcc ttcaagaaac aaaagcacca gaaggctacg cattacctaa gaatgaagct
     5041 gcgtacactg aatttacagt agatgatgat ccaacaactt ctgatgaaac aacgatcgat
     5101 aaccaaccta aaggaatctt gccttcaact ggtggtatgg ggatcatcgt attcatcttg
     5161 gtaggtactg ctttagttgg aggagcagtg atctacttca aaaaacgcca tcaagaaaca
     5221 gaagcttaaa ctattggaaa caaaaatcat acgataaata aacgatagtg attcaaatgg
     5281 ggagaaaggt tgtgacaagt ggtcggtctc ttggtattcg ctcaacaaac ggcaaaatag
     5341 gaggaactat tttgccgttt gttgagcgaa tactcaggtc aaggcgctga tttcacaacc
     5401 tcttcatata catattagaa aataggtgga catgatgaat aaaagcagaa taagaatact
     5461 ggacatcttc atggcaatca ttttagtcgt tgggatcggg atcttttctt atccttttgt
     5521 agaagattca ctgaatgatt ttcttgccca gcaaatgatc atccattatc aaaagcaagc
     5581 atcgaataag aattcagagg aaataaaaaa acagcaggaa aaaatgacaa agaaaaacca
     5641 acagttggca gagcaaaacg tatcaccagg gataggcagt ttcaaccaag cagttgatgc
     5701 aaaagcatta aaagatttac ctagtaatgc cttttttatg gaacatatgc ttggagtcat
     5761 cgaaatccca aaaatcaatg tcagcttacc tatattcgat cagacaacgg aaatattttt
     5821 gcaaaaagga acgtcattat tggaagaaag ttcttatccg actggcggga aaaacaccca
     5881 tgccgttctt tctgggcatc gtggactccc agaagcaaaa ttatttacag atttgcctaa
     5941 gttgaaaaaa ggagaccagt ttttcatcca gatcaatgga aagacattgg cgtatcaagt
     6001 agaaaaaatc caagtggtct tacctgatga agtagattct ttgggtatcc aaaaaggcag
     6061 agatctcgtg actttgctta cctgtactcc ttatatggtc aatacacatc gactgcttgt
     6121 gacggggcat cgtattcctt atcaagcaaa agaggcaaaa aaagcgatcc aaggaattga
     6181 tcaatggaaa aaatggaaat tttttatttg gtttatcggt atactacttg gatcaatcgg
     6241 cttagtttgg ctactcatcg cttatttaga ttctttggcc atcgctaagc gaaactatcc
     6301 tttatctttt tatgtaaaga acacaaacgg acgaccaatc gaaggaatgg tcttttctgt
     6361 aaaaacgctc aacggcaaac actatattac tagagaaaaa gttccatttg tgaaagcttc
     6421 tgatgaatac ggactagtga gattttctga tttaaaaggc aggaactatc gcttgcaaca
     6481 tgaggagctc ctgcttaaaa tccatgtaaa acataaacat tcgaaacagt tttcaatgaa
     6541 attgaaaaaa ggaagatata aactgcgaaa agaaaaagag gtgtactatt tgattgagaa
     6601 agaatgaatg aagatgtcca aaaaagcaga gggaacagac taaatgaaaa aagagagaag
     6661 ctgacgaaat ggacgtgtaa actgctattt ttggtttact atctggaacg ccagcttcta
     6721 tttttttatg tttcagaaga attttattat tatagtataa cttttgaatt agtttccata
     6781 acatttggag caaggggtta aaccacgagc ttgagcttcg cttaaagtgg caggggtata
     6841 cgtaccattt ccacatttat gtgtatggta ttttgaaccg gtcggtgtga catagacagt
     6901 ttgttcatta ttttgctcag gagctgcggc ttgtgcctgc tgagaggcct gttcagctgc
     6961 tgcttgctgt cgcgcctgtt ctgcttgttg ctgtgcgatt gcttcttgtt gcgcttgttc
     7021 tgcttgttgt cgtgcaattt cttcttgctt tttccgttct tcttctgctt cttttgcttt
     7081 gattgtggaa tcaattgcag caagacggct tgtcaactct tgtttgtttt caggtagcgc
     7141 ttggatagct gctgaagcag ttgcatagtt ttcttttgta ggatttgctt cagcttgtga
     7201 caaagcagat tccgcttctg tcactttttt ttctagtgca gctttttccg ctttttgttt
     7261 ctcttcttct tttttctttt caatttgttc ttgttctttc gatgaatctg ccgtactttc
     7321 ggagatcgtg gtactgctgc tggaagcctg agctgaactt gtgctttgag tagtagacgt
     7381 agtagcacca cacccactca acaaacttcc tgcgaccaaa aacaatgcaa ctaatttttt
     7441 cactaaattt cctccttaag taaaaaacaa ccgttttcaa taaatgtcct tttcaattgt
     7501 ttacttactt gttataataa ttgtgttatg aatagtgatt gaggaaactt aatctaatcc
     7561 cgttttgata cacgggattt tttgctatag ttctgttatt aagtatgcaa taataaa
//
LOCUS       DADQCX010000113         7534 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.116, whole genome shotgun sequence.
ACCESSION   DADQCX010000113 DADQCX010000000
VERSION     DADQCX010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.116"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="J8R83_002452"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="J8R83_002452"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAZ9575563.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3273)
                     /locus_tag="J8R83_002453"
     CDS             complement(2032..3273)
                     /locus_tag="J8R83_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAZ9575564.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="J8R83_002454"
     CDS             complement(3291..4214)
                     /locus_tag="J8R83_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAZ9575565.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="J8R83_002455"
     CDS             complement(4435..6927)
                     /locus_tag="J8R83_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAZ9575566.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="J8R83_002456"
     CDS             complement(6934..7401)
                     /locus_tag="J8R83_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAZ9575567.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         2075 a         1638 c         1208 g         2613 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatc
//
LOCUS       DADQCX010000114         7176 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.117, whole genome shotgun sequence.
ACCESSION   DADQCX010000114 DADQCX010000000
VERSION     DADQCX010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.117"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1145..1543)
                     /locus_tag="J8R83_002457"
     CDS             complement(1145..1543)
                     /locus_tag="J8R83_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575568.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIKFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1759..2814
                     /locus_tag="J8R83_002458"
     CDS             1759..2814
                     /locus_tag="J8R83_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAZ9575569.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQDI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDESLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2834..3187
                     /locus_tag="J8R83_002459"
     CDS             2834..3187
                     /locus_tag="J8R83_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575570.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3369..3665)
                     /locus_tag="J8R83_002460"
     CDS             complement(3369..3665)
                     /locus_tag="J8R83_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575571.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3669..4487)
                     /locus_tag="J8R83_002461"
     CDS             complement(3669..4487)
                     /locus_tag="J8R83_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9575572.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4713..4934
                     /locus_tag="J8R83_002462"
     CDS             4713..4934
                     /locus_tag="J8R83_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAZ9575573.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4936..5202
                     /locus_tag="J8R83_002463"
     CDS             4936..5202
                     /locus_tag="J8R83_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9575574.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5315..5854
                     /locus_tag="J8R83_002464"
     CDS             5315..5854
                     /locus_tag="J8R83_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575575.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
     gene            6063..6245
                     /locus_tag="J8R83_002465"
     CDS             6063..6245
                     /locus_tag="J8R83_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAZ9575576.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            6348..6632
                     /locus_tag="J8R83_002466"
     CDS             6348..6632
                     /locus_tag="J8R83_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575577.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6648..6884
                     /locus_tag="J8R83_002467"
     CDS             6648..6884
                     /locus_tag="J8R83_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575578.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            6906..7160
                     /locus_tag="J8R83_002468"
     CDS             6906..7160
                     /locus_tag="J8R83_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575579.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
BASE COUNT         2492 a         1188 c         1106 g         2390 t
ORIGIN      
        1 cgtgttaagt ttctttacat tcctacgcac cttgcgtgta aaatttcttt attcctccca
       61 cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa ccgaacaagt
      121 ttttacctat tcccaaaatt aatttattcg ttattttttc attgattaag aataattatt
      181 tgatgcttaa attagctaaa aaaacgattt tttactgata taatcatgat attaaagctg
      241 aattaggcgg aaagataaaa tgttcgcaaa atcaaagtat caattatctt gtttttttat
      301 aaatttgtaa gtaaaaatct aaaaagtttt cttttaattg gtatatgtat taaaatcaca
      361 ttcaatcact cataaaagta tgcgctttca ttttttttgg atgagattaa tatcaataaa
      421 taacgatgta aaaaccatta attatgctct tttataagga tattaattaa tctaatttga
      481 aaaaataatt caaaatttaa atgttttaat attacaaata aaatcatgtt atcgtaaaat
      541 ggtataaaaa agctaaatat tctatttttg ttattttatt agcagggaaa tttaaatagt
      601 ttacaagaat ccgtagaaat atattggttt tgccttcaga ttaatactgg atcatattaa
      661 tctgaatata atatatgaac taataaatag cttaacctcg ctattttgtt ttttctgatc
      721 actatctata cagcattagt aaatagaatt ttaaaaataa aaaaattaag acaaaaaaag
      781 tatcaacata aacatataca tatacacgtt tatgttgata cacttaattt gtcctttaaa
      841 aagcacttat tttaatatta tgttatttta taatcttatt acaagctgat tgttagacgt
      901 tgtcctttca ttacatttat taacggttat tttatcgttt aatttattaa ttatttttga
      961 tctaaaactt agcttaacaa ataaataatt aaccaaccgc cagataaaaa tgcgatcatt
     1021 gctaatacat aagcaaagat aaaaatatgt tcgatcagct taaaccctga tgcgattaag
     1081 cagaccaagt aaaatagaaa ttctcttaca gataatggta attttctaac tagcatactc
     1141 ataattaaca ccccaaagta atattgtatt ttgaacattt tacatccaat acagcatcaa
     1201 tcaaccattg ccaatcaaaa atacaaggct tcattgaagt atgtttttca gatgaaaaga
     1261 tataatataa tttcttcgga ataatatttt cagttgttgg gatcaagcta aatttaatac
     1321 catctaactc atagctacca gctttctctc cattaaaaat ttccttagca ctttcttcta
     1381 aagaatcaaa atatttttcg acagcaacct ttgaagcttt tactattgaa gcatttccct
     1441 tttcgataaa atctgctttt gttttaccga caataagtaa ttcttgatca gtaaaatctt
     1501 ctaaaataat agtagtgtaa ttcttatttc ttctcaatcg catcaggatc actccttaat
     1561 ataatttatg cttttataat atcataataa gataaatttg caagtgttta tttacacctt
     1621 tttatttaca ctttattgta attgattata cttttttgat tgcatttttt tcttataaac
     1681 agttgcaact attagtaaat aggtgtaaac tattttcgta ccgaaatacc ataaacacaa
     1741 acagaaagag gtcataccat gaaagaacca ttattgtttt ccgttgactt agggaataaa
     1801 tcagtaaaag aaatgagtac acacgtttct ccactctcgc ttccctctcg tattttgaac
     1861 aaaaatatca ttaattcagg acgtttttct aatataggtt cctcattaaa acgatcacta
     1921 aacgtttctg aatatagcct agtaaacact actgaaagct attattttgg gaaggatata
     1981 cacgagctag gaaaagatga ctacgtgata gaatcactag gttttgggat cagcagatac
     2041 aagcaggaaa cctaccaaga tatcctatct ttctctttag ctaacctagc acgtttagaa
     2101 gatcaatctg atgacgtttt aaccgttaat ctagttttag gtctgccttc atccgactat
     2161 accgaaacaa tcgtcaaata cgtgatgcaa caagccacac gacaacattc agttgaagtt
     2221 gacggtaaag cttataatat aaacgtagat accgtttggg tactgccaca gccgattgga
     2281 acactatata acctcctcct tgctgatgat ggtagtgtac aagatgaatc attgatcagt
     2341 cagaagatcg gttttgttga tattggtggt ggcacgaaac tttttgatgt tgtccaaaat
     2401 tttgaaattg acgaaaacaa ccgtgaacaa aaggataccg gtatttttac tttatataat
     2461 cgtatcgtaa atatgcttga ccttccgatc agtcctaatg ctttccaact tgaaaagatt
     2521 atccgagaag gcaaagaaaa aggcgtatat ctatttaaac caagcggaaa tgaaagtttt
     2581 gatatttcag aagtagttga aagagaaata aaaacataca ccaatatggt tgttgcagaa
     2641 gttttagcta cattcaaaaa cttcacaacc ttagataaag ttgtctttac tggtggtggg
     2701 gcttctatta tcgacaaaca acttgtaaaa gataaaattc cgcatacctt gtttgttgaa
     2761 gacagtgaat tttctaatgt aaaaggcttt tacaagtttg gtttaactca ataaaacagc
     2821 gaaggagatc aacatgaata agggaaaatc agagcgttat gtagttataa tcaatagaga
     2881 aaaggttagc gagttacctt tagcagagtt tcttgaatct gaatatgaaa cactaggcgt
     2941 taaatactct cagacgatca aaaaagcttt gaatctatat cggcgtgtaa agaacaatga
     3001 agttacaatt attgaagcag gcaacgatag aaacgatagc aaagtagctg aagtaaagaa
     3061 taaaccaact gatcataacc ctattcaaca agcgcatcct tcaacggtta catccgatca
     3121 ttcagcaaag aaagaaaagc caatgctaaa agggttcaat gcaccaagta acaaagactt
     3181 actttaaaaa taaaaaggcg aggttacaat acctagcctt tttattatgt acaaatacaa
     3241 acataaacat atacgtatac atgtatataa acatgtatac gtatatatcc ataaacacgt
     3301 atacgaaatt tagttaagct atacctaacc gcttattcca ataaaaaaag tgatcagctt
     3361 taaactgatc actcaccaaa aacttcatca tacaagttat ctatcatttc accaagtaaa
     3421 gctgaatctg atcgaattcc taacttttcg ctgattttag atagtttctt tctttgtgat
     3481 ggttgaagcg tgaattgata atttttcttc ttttcagaac tatcactttt tagtttagct
     3541 accaaagaac ttgttgtttc tttaggtgtt tgtttaggtt cttcaactgc ttcaaccact
     3601 tcaggaactt cttctacttc agcttcagcg aattttttaa atctattttc tttcacttca
     3661 atcactcctt attcttgtgc cgtatcaatt attttgttgt atagcgtaaa cgtgctttca
     3721 aagaaatcct tattcttacg atagatattc ttatccttag cgaactcagc aatattctta
     3781 ccttctaagc tagttgcatt aagcaattcc ttctcttgta catatccaag ataattagat
     3841 aacgttggta ccaattctag gaactcacga cttgaattag tattatgttt gatcctgcta
     3901 ccgatcgtag cgtatttagt ttccatcagt gtttcaccag tcttaatatc aatcaactgt
     3961 tttgctagtg catcaatatc tttaccaagc ttaagcaaag cttcaaaacc atctttagat
     4021 ggatcagaaa tgcctacgac aagatcagat acagcccaag cattttgagc tagtagacct
     4081 gcatcattat gagtatcaat cagaattaga tcatacttct ctttaagctg ttcatagtta
     4141 acaacgatcc atctaaacag tagggttctg ttgttaggca tatcacgcat ttgcatctca
     4201 acttgtttta aatcttcacc tgctactaaa atatccatgt tctcatttat agctaaaggt
     4261 tcagctgatc catgaagata taaatgattg attgtattct ctcttttcgc tttactgaaa
     4321 gcatcaggaa atcgttttga taggttttgc gacttatctt catcaatata cagcaccttc
     4381 atacctaaat tttcgacagc atatccacct agattgtaga ttgttgttgt tttacctgtt
     4441 ccaccttttt caatgtttcc agtaatgatt gacaacttct tttccatgat taaacctccc
     4501 ttattaatct tttgtaactc cattatacac tataaacacg tttatgtata tatttatata
     4561 cataaacgtg tttatattta tatttgcttt tatattctac aacataaaca tatatatgta
     4621 tatgtttatg tttatgtata tattcaaata tataactatt gcatttgtca tacaatcgta
     4681 gtacaatgta attgaaaagg agttgataaa ctatgccagt aataagtatt cgtgtatcta
     4741 aagaagaaaa agattttctt gaaaaagttg ctgaattcaa cggagataac atttctgaat
     4801 ttatgcgtag taattccctg caaacagcag aaacgttagt agactttgcc acctacaagc
     4861 aactaatgaa agagcatgag gaaaacgatc aaagtatttc ccacgaagat atgctaaaag
     4921 agttaggctt ataagatgac ttaccaagta agatatgaac gtgaagctca aaaagcgcta
     4981 aaaaaaatgg ataagtttca ggcaaaggtt atcctaaact ggatcgagaa aaatcttgta
     5041 ggcactgatg atccaagaaa gcatggtaaa ggtctaacag ctaataaatc aggctactgg
     5101 cgatataggg taggtgcata ccgtataata gctgatatta gcgagcatga agtgacaatt
     5161 cttatattgt ctattggtca cagaagtgaa gtttataagt aacagacaag ctgataaggc
     5221 ttgtctgttt ttttgttaac ccaacaaaat cactgtttac gatcccactt tacctaaaaa
     5281 agaacaatat cctcttgata ttatacacac cagtgtgtat aatataagtg taaacaagct
     5341 aattaacttt caaaaggagc gattttttat gggatggtat ggtgattatt catcagcaaa
     5401 tgaagtgatc gaagaaaaga aagggtacgc caaaaatggt ttggaaatcg taggtaccaa
     5461 agtaacgaag acctatggaa ttatcctttt caaagatgca gaaggaacct acgatattga
     5521 cagcttcatc tttcgagatg aaatgtacaa accaatctac ttcttaaatg acagtcctgc
     5581 ttactttaag aaaattccga aaaaatggtt gaaattcttt gtcggtgatc aagaaaaaat
     5641 ggttaagcta caactagata gaattaaaga agaaagcaat aaaccaaaac ttgatgactt
     5701 attagttgca ggtaaaactt actcaatctg ggatggatcg tatgtcgctg tctatcagta
     5761 taaactcaaa cgtagcttta tttttcgact acaagatgga tcactcactc ggttcactcg
     5821 actatcagca ggagatgtta aggaagtaac ctaaaactta aatacataaa cataaacgtg
     5881 tatacgttta tgtttatgta tatgtatatg aatataaacg tattaggtac gaacactttt
     5941 aaattctttt ctgggctttg tttttagggt agggctaaaa aaaacatcac catctgatcc
     6001 aaaacagctc agaaacgcat ttaaacgtat ctgataccaa tattacagaa ggagtgtatc
     6061 gtatgattaa cctatttctt ttagtgacag ctagtacatt attctttact ggaatatcac
     6121 tgataatttc ctatttgatc tataagaaag ccgaaaatca cacaagcaaa gcaatcggac
     6181 tagccgtttc atccttttta actttgctga ctttatttgt tactttatcg ttttcttttg
     6241 tttagaacag ctgatccatt agcacctttt tctctttaca ttatacacac tgttgtgtat
     6301 aatgtatttg taaacaagct aattaacttt taggaaggag tgacaagatg ctaacagcta
     6361 ctttacagca acctactcac gttgctattg cagaaagtta tacaattaat gcagggatcg
     6421 ttaaacagct gatcaaggat cgagaattca aaaagtttaa cagtcggcaa gcgtataaca
     6481 gacagctaaa gaaagctatt ctaaagcaca aagattcctt catcgggaac ttggaaagtg
     6541 tagatgttaa aactgtttca acggcatttt cagttgttga agtgactatt gacggtcgct
     6601 tgatttctct atttgctttt ggaattaatt gatagggagt gtgaactttg gaaggtaaga
     6661 cttttgcaga aatttggact gaatttattg aggtaccaac tcgcattgat ccgataactt
     6721 ctgaaaaggt attggatgca gacttctaca atctcaaagc aggtactagc cttgaatgcg
     6781 tttggatgta tttagaagag catttcaaag gcgtaacgct cggtcacgtc ttataccaca
     6841 atggtgccga gtgggatgca attggaaata tccatttttc ttaatataag aaaggagaac
     6901 acaatatgaa ttataccgat gaagaacaaa tcgctttgga atacgttttc acaaatgaag
     6961 aaggggagga aattgaaaaa gtcttgatca tttcatcaaa agacttggag aaggctttgg
     7021 cttatgaacc atacgaatca accgtaactg tcattgaatt cttagatacc tatacttcta
     7081 atgatacttg ggaaattatg aatatttgca acgctaataa cattcaattt gctgaaaaaa
     7141 ccaataaatc attttattag ttttgcaata aaacat
//
LOCUS       DADQCX010000115         6914 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.118, whole genome shotgun sequence.
ACCESSION   DADQCX010000115 DADQCX010000000
VERSION     DADQCX010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.118"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            243..1019
                     /locus_tag="J8R83_002469"
     CDS             243..1019
                     /locus_tag="J8R83_002469"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAZ9575580.1"
                     /translation="MAFQVYLQRVYILSTGVIIGHYAEMGLNRIAYAGLMGDFSFAGL
                     YLATGCLYAFLKYVDLKNWKLLFFIIIEVFLLGAILCVSARTGLVSLFVTMTLYYLFN
                     INRISVPHLLVLIGGIITTPYILVMLMAGRSGQSLLDSSGRLENYMSSLNAFSDKYLI
                     GYGLGLNNLYTLLGVAVPHNFFIQYLLQTGIIGTLIILSGFFKFTYEELKKSGCYKWL
                     FLMIVVGAMFIPDIVSSRFLYAIVVLCMISASERTIKKES"
     gene            1030..1491
                     /locus_tag="J8R83_002470"
     CDS             1030..1491
                     /locus_tag="J8R83_002470"
                     /inference="COORDINATES: protein motif:HMM:NF012360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HAZ9575581.1"
                     /translation="MRRKAEKWADKACRQYRNGQNKMSKISCYILRIIYGCEFYGQVD
                     FSSNAQLVHNGLGCVFHPKTKIGNNCKIYQNVTLGGNGKIINGKETVGAPTLEENVAV
                     FAGACVLGPINIGHDSIIGANAVVTKSVPPYSLVYGNPAIITELKFDYKFD"
     gene            1550..3007
                     /locus_tag="J8R83_002471"
     CDS             1550..3007
                     /locus_tag="J8R83_002471"
                     /inference="COORDINATES: protein motif:HMM:NF024832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HAZ9575582.1"
                     /translation="MGNNIHGKTAKALKWSSLAEIIAKIITPISNMILARLLTPDAFG
                     VVATVTMVISFADMFSDSGFQKFLVQHEFDNEEHMFSSTNVAFTSNLGISLLLWLFIC
                     VFNNKIAHLVGNSGLGLVIIVAGVSLPITSFSSIQSAIFRRNFDYKILCYARIISALI
                     PLVITVPLAIIGLSYWSLVIGSIIGNLVTAAILTKLSEWKPKLFFSKKEFYEMFSFSA
                     WSLVESLGTWLSSYIGTFIVGGILSVYYLGIYKTTMTTVNGIFAIVTSATTTVLFSTL
                     SRLQNSKTEYDKTYLDFIKIVSIFIIPLGIGIYVYRELVTNILLGSQWKEAVPFVGIY
                     GLMSCFTLVLGQYASEYYRGLGKPKANVLMTILHLAVLIPVLIIYSRKGFIELAYGRS
                     FVKIEQIIVFWIILWFGFKFNPFKILKQVWKSCASALLMGVLAKIMLEFCTNYVMQLL
                     SVCLCVILYFFIYSCIFKGKTEIINMVRMFTGKGY"
     gene            3042..4211
                     /locus_tag="J8R83_002472"
     CDS             3042..4211
                     /locus_tag="J8R83_002472"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9575583.1"
                     /translation="MKKVTILIPGMYYGGMERVAFITRQILLKNNYNVSFVTLFDNDA
                     DYQPNFEYLSLKCDIKPSKFGKVINIFKRVYKMKSVKKKLKTDITISFGQSCNLVNVL
                     SKRDDKVYVGIRSYDWLFQYIFHYYVDKFVYKKADAVVSVSQLIKRDAENIFNFNKDK
                     SYFLYNPYDLELINNKSKEKITEIEVPTDKKIIVTVGRLEDQKGLYHLIKAISMLKNK
                     DNVVVYILGHGTKKELLENLIKAYQLQNVIFLLGGQSNPYKYMSRADLYVMPSITEGF
                     PNALVEAMSTETAVLCADCKSGPREILSNRTLDTICENIEYAESGILVCPMTDSRNYS
                     PQYEECDKNLANAIEELIENDNLRNKYAKAAKKRAELYSYDAFEHNLLQIMKTFN"
     gene            4249..5340
                     /locus_tag="J8R83_002473"
     CDS             4249..5340
                     /locus_tag="J8R83_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAZ9575584.1"
                     /translation="MLKKNTSLQNKTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFLFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(5408..6886)
                     /locus_tag="J8R83_002474"
     CDS             complement(5408..6886)
                     /locus_tag="J8R83_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAZ9575585.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRVESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
BASE COUNT         2299 a          915 c         1252 g         2448 t
ORIGIN      
        1 ttttgatgtt atatattatt atagaaggaa cattaaatcg ttcatacttg attattttat
       61 ttttatttat ttgttttgga atatcgacgt ctatgttctt acctttttta atagatgcat
      121 taaagcaatt aatgactatt tcgttgttta tctgtagttt tttaatagga aaacgtttta
      181 aaatgtatag caaaaactta actatgattg ggtggaattt ctatttcata ggagtagtat
      241 ctatggcgtt tcaggtatat ttgcaacgag tatatatttt atctactggt gtaataatag
      301 gccattatgc agaaatgggt ttaaatagaa ttgcatatgc aggtttgatg ggagatttta
      361 gttttgcagg gttatatctt gctacaggct gtctatatgc ttttctaaaa tatgtggatt
      421 taaaaaattg gaaattatta ttctttataa taatagaagt atttttatta ggtgcaattt
      481 tatgtgttag tgcaagaaca gggttagttt ccttgtttgt cacaatgaca ttgtattatc
      541 tatttaatat aaatagaatt agtgttcctc atcttttagt tctaataggt ggaatcataa
      601 ctacacctta tatactagta atgttaatgg caggtcgttc tggacaaagt cttttggatt
      661 cttcaggcag attagaaaac tatatgtcct ctttaaatgc ttttagtgat aaatacttaa
      721 taggatatgg attaggatta aataatttat acacgctact aggtgtagca gtaccacata
      781 atttttttat tcaatattta ttacagacag gaattattgg tacgctaatt attttaagtg
      841 gcttctttaa atttacgtat gaagaattaa agaaatcagg ttgctataaa tggttatttt
      901 tgatgatagt agtgggagca atgtttatac cggatattgt atcttcgcgt tttctttacg
      961 caatagttgt tttgtgtatg atttctgcat cagaaagaac tataaaaaaa gaaagttgag
     1021 gtagaaaaaa tgagaagaaa agcagagaaa tgggcagata aagcttgtag acaatacagg
     1081 aatggtcaaa ataaaatgtc aaaaatatcc tgctatattt taaggattat ttatggatgt
     1141 gaattctacg gacaggtaga ttttagctct aatgctcaac tagtccataa tggtcttggt
     1201 tgtgtattcc accctaaaac aaaaatcggt aataattgta aaatatatca aaatgtgact
     1261 ttgggtggaa atggcaaaat aataaatgga aaagaaactg ttggggcacc aacgctagag
     1321 gaaaatgtgg ctgttttcgc tggtgcatgt gttttaggac caattaatat cggacatgat
     1381 tcaatcatag gtgcaaatgc tgtagttaca aaaagtgttc caccatatag cttagtatat
     1441 ggaaatccag caatcataac agagttgaaa tttgattata aatttgatta aaaagtaatg
     1501 tttaatatgc gaaaggttgc tatatttatt tagcaaaatg gggtaataaa tgggaaataa
     1561 tattcatgga aagacagcaa aagctttaaa atggtcatcc ttagctgaaa taattgcaaa
     1621 gattataact ccaatttcga atatgatttt agctagatta ttgactccag atgcttttgg
     1681 agtagtagcc actgtaacta tggttattag tttcgctgat atgtttagtg attcaggatt
     1741 tcaaaaattt ttagtacagc atgaatttga taatgaagaa cacatgtttt catcaacaaa
     1801 tgtagctttt actagtaact taggtatttc tttattatta tggttattta tttgtgtgtt
     1861 taataataaa atagcgcact tagttggaaa ttctggactt ggattagtaa ttatagtagc
     1921 tggagtttct cttccaatta cttctttttc cagtatacaa tcggcaattt ttagacgaaa
     1981 ttttgattac aaaattttgt gttatgctag aataatatct gcattgatac ctttagttat
     2041 tacagtaccg ttggcgataa ttggactaag ttattggtca ctagtaattg gatctataat
     2101 aggaaattta gttacagctg caatattaac taagttatca gagtggaaac caaaactttt
     2161 tttttcaaaa aaagaatttt acgaaatgtt ttcctttagt gcgtggtcac tagtggaatc
     2221 attaggtaca tggttgtcat cttatatagg tacttttatc gtaggaggca ttttaagcgt
     2281 atactatttg ggaatataca aaactacaat gacaacggtt aatggtattt ttgcaattgt
     2341 aacttcagca acaacaactg tattattttc aacattatct cgtttacaaa atagtaaaac
     2401 ggagtatgat aagacatatt tagattttat taaaattgtt tccattttta ttattcctct
     2461 gggtataggt atatatgtat atagggaact agtaacaaat attctactcg ggagtcaatg
     2521 gaaagaggct gtaccatttg ttgggatata tggattaatg agctgtttta ctcttgtctt
     2581 gggacaatat gcctctgagt actatcgtgg tttaggaaaa ccaaaagcaa atgttcttat
     2641 gactatccta catttagcag tattaattcc agttctaata atctattcaa ggaaagggtt
     2701 tatagaacta gcatatggta gatctttcgt taagatagag cagattatag tcttttggat
     2761 tattttatgg tttggtttta agtttaatcc atttaaaatt ttaaagcagg tttggaaatc
     2821 ttgtgctagt gcattgctaa tgggagttct agcaaaaatt atgttggaat tctgtactaa
     2881 ttatgttatg caattacttt cagtgtgtct ttgtgtaatt ctatattttt ttatatatag
     2941 ttgtatattt aaaggaaaaa cagaaataat taatatggtt agaatgttta ctggtaaagg
     3001 atattaagag agatttttat ggcaaggttg tgattaggaa aatgaaaaaa gtaacaattt
     3061 taattcctgg aatgtattat ggtggaatgg aaagagtagc ttttataacg cgtcaaatac
     3121 ttttgaaaaa taattataat gtatcatttg taactctttt tgataacgat gcagattatc
     3181 agccaaattt tgaatattta tcattaaaat gtgatataaa gccatcaaaa tttggtaaag
     3241 taattaacat ttttaaaaga gtttataaaa tgaaaagtgt caaaaaaaaa ttgaaaacgg
     3301 atataactat atcttttgga caaagttgta atttagtaaa tgttttatca aagagagatg
     3361 ataaagtata tgttggaatc cggtcctatg actggctatt tcaatatata ttccattact
     3421 atgtagataa atttgtatat aagaaagcag atgctgttgt gtctgtcagt cagttaatta
     3481 aacgtgatgc tgaaaatatt ttcaatttta ataaggataa aagctatttt ttatataatc
     3541 catatgattt agagttgata aataataaga gtaaagaaaa aattacagaa atagaggttc
     3601 caacagacaa aaaaattata gtgacggttg gtcgattaga agatcaaaaa ggtttatatc
     3661 atctaattaa agctatatct atgttaaaga acaaagataa tgttgttgtg tacatcttag
     3721 gacatgggac aaaaaaagaa ttattagaaa atttaataaa agcatatcaa ctacaaaacg
     3781 taatattttt gctaggtggc caatcaaatc cttataaata catgtcacgt gcagatttat
     3841 atgtcatgcc atctataact gaaggttttc ctaatgcatt agttgaagca atgtctacag
     3901 aaactgctgt cttatgtgca gattgcaaat ctgggccaag agaaatatta tcgaatagaa
     3961 cgctagacac gatttgtgaa aatatagaat atgctgaatc aggcatatta gtatgtccaa
     4021 tgacagacag tagaaattat tcgccccaat atgaagaatg tgataaaaat ttagcgaatg
     4081 ctatagaaga attgattgaa aacgataatt tgaggaataa gtatgcaaaa gcagcaaaaa
     4141 agagagcaga actatatagt tatgatgcct ttgaacataa cttgttgcaa attatgaaga
     4201 catttaatta attcatatga tgaaataaaa ataagggagt ataactagat gctgaaaaaa
     4261 aatacatctt tacagaataa aacaatatta ataactggcg cagccggttt tattggatca
     4321 aatttggttc ttgagttatt acgtactcag tcatcaataa aaatcattgg cattgacaat
     4381 atgaatgatt actatgatgt ctctattaag aactatagat tatcagagat agaaacggag
     4441 gcaaagaacc atccaggatc tacttggaat tttatcaaag gttctattgc tgataaagca
     4501 acaattgatt tcctctttga taattataaa ccaagtatcg tggtgaattt agcagctcag
     4561 gcaggagtcc gttattcaat tactaatcca gatatgtata tcgaatctaa cataatagga
     4621 ttctataata ttcttgaagc ttgtcgtcat tcatatgata atggagaatc tggtgtggaa
     4681 catttagtgt atgcctcatc gtcttccgtt tatggtacta ataagaaaat tccttattct
     4741 acagaggata aagtagacaa tcaagtatcg ttgtatgcag caactaagaa aagtaatgaa
     4801 tcaatggcac atgcatattc taaactttac aatattccgt ctacagggct acgtttcttt
     4861 acagtatatg gtcctgctgg tcgtccagat atggcttatt ttggttttac tgataaactt
     4921 cgtgctggtg ataatatcca aatattcaat tatgggaatt gcaagcgtga ctttacctat
     4981 atagatgata ttgttgaagg agtaaagagg gttatgcagt gcgctccaga gaaaattgat
     5041 ggggaagatg ggctaccaat cccaccatat catatttata atattggtaa caatacgccg
     5101 gaaaacctac tagattttgt agatattcta caacaagagc taattgcagc aggggtgcta
     5161 ccagaagatt acgactttga atctcatacc gaactagttc caatgcaacc aggagatgtg
     5221 ccagttactt atgcagatac tagtgcgtta gaacgagatt ttgaatttaa accaagtaca
     5281 agtttgcgtg acgggcttcg taaatttgcg cagtggtata agtcttttta tgaagtataa
     5341 ttgtattttt ttacttataa aagtttatag aaacacctca gacactacaa atctgaggtg
     5401 ttatttttta atctcgttga aataaatctc tggtatatac tttttctttt acatcatcaa
     5461 gattactatc gtaacgatta gcaataatac tgtgactgat atttttaaaa tcatctaaat
     5521 tatttattac ttttgaacca aaaaatgtag tgttattttc aagtgttggt tcataaatta
     5581 caatagttgc cccctttgct ttaattcgct tcataactcc ttgaatagat gactgacgga
     5641 agttgtctga attactcttc attgtaagac ggtatacacc tatgactacc tctttttctt
     5701 tttctgcatt ccacgaactg ttagcctcat acgtgccagc aagttctaac actcgatctg
     5761 ctataaagtc ttttcttgta cgattactat cgacaattgc acttatcata ttctgaggaa
     5821 catcgttata gttagtgaga agttgttttg tatctttcgg taaacaatag cctccatatc
     5881 caaaagatgg attattataa tgtgtgccaa ttcttggatc taagcaaacc ccgtgaatga
     5941 tttcttgtgt atttagtcct ttcatttctg cataagtatc cagctcattg aagtaagata
     6001 ctcgaagtgc aaggtaagta ttagcgaata atttaactgc ttcagcttct gtgaatccca
     6061 tgaaaagagt ttcgatatct tttttgattg ctccttcttg gagtaaatct gcaaaagtgt
     6121 gagaggcttc tcgtaaagtt ttgtcagttt ggtccgtgcc gacaataatt cgcgaaggat
     6181 atagattgtc atataatgcc ttagattctc tgagaaattc tgggctgaat agaatatttt
     6241 tagtattgta ttttttacga atactttcgg tatagcctac gggtaccgtc gacttgatga
     6301 ccattattgc ctttggattg acttctaaca ccaatttgat tactgactct acagcagaag
     6361 tatcaaaata attttgttta ctatcataat ttgttggagc agcaatgaca acaaaatcgg
     6421 cttctctata ggcggctgca ccatcagtcg ttgcaattaa attaagattt ttttcagcta
     6481 gatatttttc aatgtaatcg tcttgtattg gagatttctt attgttaatt tgttttactt
     6541 tttcaggaag aatgtctact gctgttacct gattgtgctg ggcaagaaga gtagcaatgg
     6601 aaagacctac gtaaccagta ccggctacag caatattctt cgactgatgt tttgttctgt
     6661 ttgatttatt tgattcattt ataaatagat ctgttggttc aaaatttaga acttctgcta
     6721 atgattctaa ttgttgtatt gacgggataa aatcgagaga ttctactcga ctaattaagg
     6781 cacggttgat accagtagct actgcaagtt gttgttgtgt cattttcaga gattttctag
     6841 aatcaataat gatttgagct aaacgttttt gagataactt tttcatgatg cactcctttt
     6901 tttgttgcta ataa
//
LOCUS       DADQCX010000116         6652 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.119, whole genome shotgun sequence.
ACCESSION   DADQCX010000116 DADQCX010000000
VERSION     DADQCX010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.119"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            138..959
                     /locus_tag="J8R83_002475"
     CDS             138..959
                     /locus_tag="J8R83_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAZ9575586.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            979..1539
                     /locus_tag="J8R83_002476"
     CDS             979..1539
                     /locus_tag="J8R83_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAZ9575587.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2428..3195
                     /locus_tag="J8R83_002477"
     CDS             2428..3195
                     /locus_tag="J8R83_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAZ9575588.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3221..3766
                     /locus_tag="J8R83_002478"
     CDS             3221..3766
                     /locus_tag="J8R83_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575589.1"
                     /translation="MGERTQALITVKYGNSKTKAGVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3767..4333
                     /locus_tag="J8R83_002479"
     CDS             3767..4333
                     /locus_tag="J8R83_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575590.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            4348..4596
                     /locus_tag="J8R83_002480"
     CDS             4348..4596
                     /locus_tag="J8R83_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575591.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4615..4854
                     /locus_tag="J8R83_002481"
     CDS             4615..4854
                     /locus_tag="J8R83_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575592.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            4871..5455
                     /locus_tag="J8R83_002482"
     CDS             4871..5455
                     /locus_tag="J8R83_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575593.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            5562..5843
                     /locus_tag="J8R83_002483"
     CDS             5562..5843
                     /locus_tag="J8R83_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAZ9575594.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            5833..6174
                     /locus_tag="J8R83_002484"
     CDS             5833..6174
                     /locus_tag="J8R83_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9575595.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         2503 a          863 c         1363 g         1923 t
ORIGIN      
        1 ttcaattatt gtgaaatatt tccctttaat taatcaaatt ttttataaaa gtaatatata
       61 aaataaattg cttgaagtat tatatttaga tatcataatt tatggaagaa aaattaatta
      121 aaaaggatga gattataatg gggttactgg ttccgagagc taatacttat actatacctt
      181 taacgaaacg ccaattaatt gctaaaagat atcaaaggat tactagagcc atcaatagag
      241 agttttggaa ttctgaaagt gatactgctc acagtttata cgtaggttct tatgggagag
      301 gaacggcaat tagtactagt gatatagata taatagttga attaccgatg gcagaatttg
      361 acagattcaa aaattattta tcaaatggcc cgtctaagtt attacaagtt ataaaaaacg
      421 catttcagga aatactacca aatagtgata ttagagctga tggacaagtt gttaaaataa
      481 atttccatga tggaatcaaa tttgaaatag ttccagcttt taatgaaaaa gattattggg
      541 gtgagtcaaa agggtttatt tatccagatt caaacatggg agggaactgg aaagctacaa
      601 atcccaaaaa agagcaagaa gccatgaaat taaagaatac aaaaagtaat aatttattat
      661 atgctacgtg taaacatttt cgacatgtac gagatacaga atttacgagt tatcatcttt
      721 caggaatagt aattgacagt ttcgtatatg aggctatggg aaattggaaa ttcgttgaaa
      781 ataacagtgg gggtcaaaac attagttctg tatcttatga gacagcttta ttagaatact
      841 ataactcaca taaagttatg ggcggtttaa atttatactc tcctggaagc aatcaatttg
      901 ttaattctga tagtagtatc atatgtttag aaaaagtatt aaaaaaaata gctttataaa
      961 gttttatgga ggaacaacat gggagacgaa aaaaagcgct tggaagttca attacgtgaa
     1021 gcatatggac gagtaacgta tacttacacc actcatttaa agcaagccga taatattatt
     1081 tctgacaata aaattttaag gtgtcttcaa attggtttgt cagcccttac tactggaggg
     1141 gtacttagta ccattattac tgataatagt gagttaacct ttgttgctgg attatgttca
     1201 acaatttctc ttggattaaa cttatacttt aagaattttg atcttgctga agaagctaaa
     1261 aatcatcaaa ttgttgccga taaattatgg ttgatcagag aagaatacgt aagcttacta
     1321 acagatttaa atcgtttaag tgttgaagat attgtgaaaa aaagagatca attaatgaac
     1381 gaaactcatg aagcatataa aaatgcccct aaaacaaata gtaaaagcta tgaatcagct
     1441 cagaaagcat taaaatctga agaagagcaa ttttttacag aagaggaatt ggataagatg
     1501 ttaccagagc atcttagaaa aaagagttct aaatattgaa ctcttttttt atgcttaaaa
     1561 ttctcttgta atttttctat tcatctatat ttaagaagaa atatgatgat agaaacatct
     1621 cctaaagcca ccgcaagccg ttctaagcat agcttagccc gacattgcta gatatgctca
     1681 tctcaccatg aacgtttcct aaagccaccg caagccgtcc tagccattgc ctagtccgac
     1741 atcgctagat tagtgcatct cgccataaaa gttttctaaa gccaccgcaa gccgttctaa
     1801 gcatagctta gcccgacatt gctagatatg ctcatctcac catgaacgtt tcctaaagcc
     1861 accgcaaacc gtcctagcca tcgcctagtc cgattttgct tgatcggttc catttctgtt
     1921 tatttagtgg gtcaacaccg taatcttaaa tagccatcgc ctatttaaga ttactaggtc
     1981 tgctttgaag gtaaaaagtc tttcattctt caagactttt aggctttcaa gctacgcctg
     2041 aaagcattga aattcatcgc tctttatttg gttttgccat ttataattcc ttacgcccat
     2101 tatctttttc gcctgtcata ccttgtcaga agtgtttaga gcttatctca tctttggatt
     2161 aatacaagtg gcgtaaattt ttttctaaac gcaagcgtta cgaaaataat ttacttaaac
     2221 acttgtatta atccggcaga taagaacgca ttctaatcac tcccgacaag gcaagacagg
     2281 cgaaaaagat aaataaatga acgaaaggaa gaaacataaa atgcaaaacc aaatagcgat
     2341 gaagaaaaaa ccacctccct ctaaaacaat ccaaacaaaa aagaattttg aaaaaccaaa
     2401 aatcaaaaac agaaagaagc gttcaacatg agagatagaa ttttagaagt taatcaagaa
     2461 atggtaaaca agttaacaaa tatcagtggg aactatgaaa agtacgatgg tactttactt
     2521 gataactata tttttcacga tacacaaaat atcagaattg gcagaagtaa accgagagcg
     2581 ttcattctca tcaaagagaa atatttgaat gaatggaata gcacctatga aatggttatg
     2641 actgataact ttgaaaaggt attggatttc agaaatgctt tgttgggttc tgatatggga
     2701 aatagcagtc ttgaatctat tgaagttgaa aacaagaccg agaatgaagg tgaaggattg
     2761 attaagaatg tcttgaaaat cgaacaaaaa tatatcagtg aagatagaag tttttataga
     2821 gtcacaagct cggttggtct agcaaacttt gctactaact taattggaaa caatgctagt
     2881 gaatctttgc tagtgatgtg tctgaataca aagaatgagg tcattgctta tagcgaagtt
     2941 ttcaaaggtg gaattaatca atcagtagcg ataccaagag agatttttca actagctttg
     3001 ctaaacaatt cagcaaaaat cgcagtatca cataatcatc cgagcggata tgaatttcca
     3061 agtgaaaatg acaaaagttt tactacgaat ttgaaaaacg caggaaaaac aattggtatt
     3121 gaattgttag accatatcat cgtaacaagt aaaaacacaa gctattactc atttcaagaa
     3181 aatggttctt tataaaaatt agagaaaaga ggaaaacaag atgggcgaaa gaacacaagc
     3241 gttaattaca gtcaaatatg gtaacagcaa aacgaaagca ggcgtgtcga ttcattatca
     3301 gtgggggtat ggtcgatata tgctgatgga cgtattgaat caaggaattt atttaatcaa
     3361 taaagcatac gacttacgag ataaatcaag agaagaatta gcaaaaggaa tctttgatag
     3421 aagtacagga gttatcaatt ttgtcaccta tgaatctgga gtgagtgctt atgatgaaac
     3481 agggtttggt gggcgctatg aaccttatca agaaacgatt gaagatgtga tgaagttttc
     3541 agataacaat gatggctatg ctcatttaga gatggtgttc gatgaaaatg gatttagtct
     3601 agatgataaa accagattgc gattgtttga ttttgagggt caacagatag gactaaacaa
     3661 gttttgtgaa agcggaaaag agtttgctac gaaagatttt attaagggat acagattatt
     3721 gctagaaaat tatggaataa acctagaaga agagagcgtg aaataagtgt ttgaaaaaag
     3781 aaaagaccag ttccctaatt tagaagcgaa aagtcaaaaa gtgattgatg gtgaaatgat
     3841 tgaattattc caaaaaagtt atggaaccat agaaactacc gcaagttgca aatactactt
     3901 tcaaggaaag agaaacacgt ttaaaggctt tgccgattct gatgaagaat tggcaaagaa
     3961 aatcattgat tggcttgtca gcagtgaaca cgtagcaaga gaagataccg ttagaacaac
     4021 gattaatggg gaagtcctaa caggtactag atgtgtttgt tgtaatcatg aatttgtaga
     4081 agatgaaggt tgctaccgaa tcaatgaata tggtgatttt atttgccaga gttgccacga
     4141 gatagaattt ccaaccgaaa gaagttggtt tgaatacatg ctacaagatt atgagatgga
     4201 aacagaaaat ggtgaagtag ttttttgtac caaagaggaa ttgagtaaga gaagcgatga
     4261 tgaaattgaa gattggtgtg tgtggttagt agggacagat gattgcgttg catattacac
     4321 aacagcagaa taggagtgtg aatcagcatg gaaggaatgg attttataga tcatgaagat
     4381 ttgattgatt ttggttatac atggaaagga atggtaggta ttagcagaag tcttgctaat
     4441 gccttttacg aaagaaatta tgcagtctat gtcctttatg atgacaatac agaaagcctt
     4501 gttgatgaag agtataaatt ggatttagag aatgttttat atgggataga aaaagaagat
     4561 ttagcaaaat atattttttc atggttgggt caataaacga aagagggtag caacatgaca
     4621 aaattcaaaa gtaaaggtat gcaatggtgt tcttattatt atgttgggaa tgatgaagag
     4681 cttttgagaa aagccaaaca aaaaggttat ccagataaga tgttaaaaca gattggctat
     4741 tacatgccag aagagagaat agaaaaagaa tcttgtaagg ttctttttga tagtgaacag
     4801 ctattagttt tgttaactca aaataaattg atttgtcaat ttgaaaataa ttaatatggg
     4861 gtgaagaacc atgaatgaga ataagatggt attaagtgaa tacgcaagat tgagaaccat
     4921 taattggttg aatggtatgc aaagtagtgg cgcttttgat ggatttgatg aggagaatat
     4981 ggactttgaa agtttatcga atgaggatat tagatattat tttatcgaat ggtattttac
     5041 agaaccagat gaagaggtgg aagatgaacc agaattaatt ttagaacgtc aaagaatttt
     5101 attcagtgaa caagatagta agaggttgta tggtttatat gacttacaac tgaaaggatt
     5161 aaaagcgcag tatgttgctg atagttacga tgatatggta gaacaggggg cagatagggt
     5221 tgtcacttat tcagaagatg atgaagagga atgggaaaac tattcagatg atgagatatg
     5281 ctttaatgat gggtatatgc ctattgaaat caccgaagaa gaatatgata aagtgtcgga
     5341 tagcgatgag attggtatgt gtacggttgt aagtggattg gatatagatg tccaaagagt
     5401 agaggttgca taccagaaga tgaaagaacg tataaaaagt aaagtagaat cttgatttga
     5461 ttggattgtt tgcaaagtag ctaattaaga gtataatata atcataaatg tagttaatgg
     5521 atataataat gagtatatta tactcaaaag aggtgaacga aatgaaggta aaaaatccaa
     5581 aagaaaaaag cagaattcaa gtcggaatag acaaggattt aaaagaaaac gcagaaatga
     5641 tattggaaga gctagggtta aatccaacaa cagcaatcac aatcctttat aagcaagtgg
     5701 tcgctagagg tgagtttcca gtagagataa agctaagcga agaggaaaag caaggaatca
     5761 gattgcaaca gctaactatg gatatgccag ttgatgttct agatacagat gaaaagttag
     5821 aagagtggtt caatgaagcc taatgagata gtaacggtct atgttgcatt tacagataaa
     5881 aatggtggta aaagaagacc tattttggtg gttagtgata aagaagatag agtagaattt
     5941 tttggaatca caagtcaata tgagaataaa tcagaccaaa taaagagagt gtattttcct
     6001 attgcagaat gggaaaaagt aggtctaaag aagcaatcat ggattgacgt agggtcttta
     6061 aaggctattc ccaaaagccg agagaacata tcatttaaaa aggttggtat gctatcagct
     6121 attgatacga aaaagctaaa taggtttatc gagagattac aaagaaaagt ctaacaaggc
     6181 ttttcttttt ttgtttatat gtatattaag atatacgttt atataaacgt atttatgtat
     6241 attaaaatac acgtaaatat atacgtgatt ataaaaatta agaaaatatt aagtattgtt
     6301 aaatagtgat aattagtaat atacgaatta taagatacat tttatattta atgtatgtaa
     6361 ataaataaaa tgactgacgg atattgaata gtaataaata acaataattc agacggatac
     6421 agtgagtgaa gtagcttgct acgaacgaac aggcagaatg aaacggtagt ttcattagag
     6481 caagtcgctt gcgacgtagc gttaccactg atgtaactgg caagttacat agagagagtt
     6541 tgcttgcaaa cgaacgttac ccacttgaat agaaaacaaa aataacatat tagtgaattt
     6601 tgaataggag ccacaactca accaaccgct tgcggtgggt gagtcccacg ga
//
LOCUS       DADQCX010000117         6631 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.120, whole genome shotgun sequence.
ACCESSION   DADQCX010000117 DADQCX010000000
VERSION     DADQCX010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.120"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            147..2822
                     /locus_tag="J8R83_002485"
     CDS             147..2822
                     /locus_tag="J8R83_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAZ9575596.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3004..3243
                     /locus_tag="J8R83_002486"
     CDS             3004..3243
                     /locus_tag="J8R83_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575597.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3259..4632
                     /locus_tag="J8R83_002487"
     CDS             3259..4632
                     /locus_tag="J8R83_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575598.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4636..6270
                     /locus_tag="J8R83_002488"
     CDS             4636..6270
                     /locus_tag="J8R83_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575599.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6433..>6631
                     /locus_tag="J8R83_002489"
     CDS             6433..>6631
                     /locus_tag="J8R83_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575600.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2322 a         1071 c         1332 g         1906 t
ORIGIN      
        1 tgtgatttcc aaaatcacaa cttttttctt ttgtcaagat tttgagtggg atatattttt
       61 gtagaactga agatcatgaa attatgagag gttggaggta atgtagtcat acaaataaaa
      121 attttttaga aagtgagtgg taattaatga aaatgaatca cacttcaatt cagaagcatt
      181 tacaactgtt aaatacactg gggatttctt atgttaattt gagaactttt tctacattaa
      241 acaagaaaac cgtttctcat attttttcta ctgcagattc tcaagcaatt attaactatt
      301 tagaaaaaca gaaattgtct gaaggtacag taaacataac ttataatcct attaaacaag
      361 aggtgattac acaaaaaaag cattctgtga gagacaatga tattgaaaaa attcggtttg
      421 tatttattga tattgaccct aaaaggaaag agggaagtgc aacagatagc gaaaagaaaa
      481 aggcagaaaa tgttatggaa caagtagaac gttatttgaa agaaaagaga atagaatcat
      541 ttgtaaaagt tgatagtggg aatggctacc atatttttct tcccataaat gaacaaccaa
      601 ataatcacga gacgattctt actattcaga attttcttca attacttcac cgaagatttg
      661 gagtagaaga tgaagttgat attgatactt ctgtttataa tccttcaaga ttatgcaaat
      721 tagttggtac accagcggtc aaaggaaagt ccacaaaaga gcgtccgcat cgtttatcta
      781 gtttcctttc tattcccgat aacatagata gaagtaattg ttttaaaatt cttgaacaga
      841 tagttgaaga aaattccatg atgtcaacct ctagagtaaa aagccatcca tcttttagag
      901 aagtgttacc ttttattcaa gcagactata aacaatggtt agctcactat cctgaattaa
      961 cttataccat aaaagagggc gatcataaag gagttacctt acttatattt gacgaatgtc
     1021 cattaagaaa acacacgaat aattctaatg gttcttgttt gtctgttacg gctgataata
     1081 agattcgatt tcattgtctg catgcttcgg ataaaaataa agatattcaa gactttgtaa
     1141 aaaaatatcc gttgccaaaa cctgtaaatc cttctgtaga atcattagaa tccaatcaag
     1201 aatattattt tgaccagttt aaactgaatc aagaaggagt atttttggtg aaagaaggtc
     1261 aagaagaaaa agttgcttgt ccgatgttta ttaagcaaat acgcaaaaat atcgaacaaa
     1321 aagtcattac acttgttctt gcctattatg tcgatcattg ttgggatgaa atagaaatag
     1381 aaggtggatg tttacaaact aataatttta aacaattagc aaaacatggc ttaatcatta
     1441 aagctagaag agaagctgaa gtcgttgact ttttacagat tcaacgggag aatgctccaa
     1501 tcttttttga acatgaatct cttggctgga aaaaagaaaa tgaagcaatg atttttcagt
     1561 tacaagattc ttttggacgt gaaattcctt ctgtattaac taaaaactca tgctaccaat
     1621 taacaactaa tggtacagaa gcggaatttg acgcattggt tcataagtat gttttaggaa
     1681 cgaacttaga acttgcttgg tcgattggta ttgcttctat tgtgttaggc tatttaaacg
     1741 ttacgaaggc taatactttt ttgagtttac taattaacct acagggcaag agcacaacgg
     1801 gtaaaaccac tacgttacac tttattgcct ctttatttgg aaatccaact acggttctta
     1861 gaaatatgaa tgctaccaat aaagccatta taaagctagc atcaaacaat cagggaggtg
     1921 ttccactaat actagatgag ttaggagcag caactcaaaa taactttagc tcgttgatct
     1981 atcaattagc ttcaggagaa gaaaggctaa gattagattc taattgtcag cttatgccac
     2041 aagagacttt ttctgttttg acccttacct cttctgaaga gcgtttggaa aattatttca
     2101 atgagaaatt aactggtttg aaagttcgat atatcgaatt ttctgatatc aagtttacaa
     2161 aggatgcgaa tcacgcagag aaagttaaaa gtctttcttc taatactttt ggttggggta
     2221 taaagttatt tcttttgaaa ctctttgaac aagggattac aaaaattgaa gcaacttttg
     2281 tcgaagctca aaaaaaacta tgggctgttt tacctgaaca ttctttgaag caacgcattg
     2341 gtaataatct agctttgatt tatagtggag ccctcctaat tcaagatata ctgggctatc
     2401 ctttacgatt agagcatata cagacggtgc ttattaattc gtacgaacag ttaattgtag
     2461 atactagttt aggaagtgag caaacggtat ttgaccgagt gaaaacattg ttggtgatga
     2521 atagccataa atttttaaca aacagtgaca acaaacatac gcccagtacg atttggggaa
     2581 aagtatcaat tcaaaaaaat ggggatatta aggtaaatat ttttcctatc ccgtttgagg
     2641 acttgttaag gcgagaattt caagtaaagg atctaaccta tctttttagg caattgcttg
     2701 attcgggtaa tatgtgtgca gaaaaaggga gaagaacgaa acgtattcac atgaatcgtc
     2761 aagttcttcc aacatacgag attctattac cttcttcact caaatcgtat tttcgattgt
     2821 aatttagaat aaaccaaagt atgaaagtga ggcaccatgt tatggaaata tttcttattg
     2881 atttagcaaa acaactgatt acttatctgt atgatagcga gcaaacccaa acggaagtaa
     2941 atgaagcttg atctatgctt catttacttc attcaatcaa acatgaaaga aaggaaaatt
     3001 ctaatgacta aaaataaaat gacactaaaa gcagaggttc ttctgtatat tcaagaacat
     3061 ttttcaaatc aagccttttt tacaaaacca atttacttgg atttcgaaat aagaggggta
     3121 tctgctggat ctatcggggg tactcttcaa gcgttgaaga acgaaggata tttagaaaat
     3181 cactttgtgc aacgttcgtt caatagaaga gtcgtgaaaa aatggtattt agttcattca
     3241 tagagagggg aatcaagcat gcgtgtggct tgttatgatc gaacgtctgt ttatgaagaa
     3301 gcgaaaatta gtaatgacgc tcaatatgat gcagtgaaag agtatgtttt agagaaatat
     3361 gaacaaattc cccaacgatt ttcagacaaa ggagaatcag gggaaaaagc ggagcgtcca
     3421 gcttttcgac agcttagagc ttgggtttgt gcgtcagaag aagagggggt gatctatgtt
     3481 tggcgttatg atcgattggc acgtcaagcc aaaatagcct tagaatttat tgagttgtgc
     3541 caacaacatc aggttcaagt gtattcgatt tctgaacctc ttcctgcttc tttctcacac
     3601 gcgtcaacga ataaactatt tgtgcaatta ttgttcactt ttgcagaaca acaacgaaac
     3661 gtcattattg agaatgttcg tgccggactt tcctataaaa agcaacaacg gcaatatttg
     3721 tcttctgcgg taccatatgg gtatcgttta gtgaatggga aaatccaaca agaagtacac
     3781 gaagcaagga ttgttcgcta tatttttcaa ctttatttga ccaaaaaata tggctacaaa
     3841 aagctttgtc aacgattgac gcaacaaaag cttttcttcc gcgaacgtcc ttttcagccc
     3901 tatcatattt atagtatcct aaaaaatcca ttgtactatg gcgaaatcaa aggaggatct
     3961 ttggggaagt atctaggaac ctttgaaccg attctctcga aagcaacctt tttacaagcc
     4021 caagagattc gccaatcaag gtgtacagct aaaaaagata cgtatctgta cttattacgt
     4081 caaaaaattc ggtgtccctt ctgtggtcgt catctgagtt cgaagtatca atggaataca
     4141 aagaagacga agacgcttca ttattatcat tgtaccgacc gaagctgcca aggaattttt
     4201 cttcgggcag aaagggttga gtcagaagta ttggaaaaga tacaggcttt ttttcaatac
     4261 gaaggcgtct atcaagcctt gattgcccaa ttaacgcaac aattagccga aaagcgaaaa
     4321 gatgaaaaac gcaaagtaat ccaacaaaag aaacaagaag cacaatggat taaggcattt
     4381 gaagagggca attgttcact ggaagaactc aagcaacaac tgcaagctct tcaaaagccg
     4441 atgtctactt cttcgtttct ttcactccaa cagtgtgaag caaaagtgaa agaatggctt
     4501 caactaaaag acctctctag tcgacaatta ttatgtgact atgtttgtcg gattgaggta
     4561 acaaaggata aaacagtttg tgggatttac ttccgacaac tgacacaaaa tattttagaa
     4621 aggaacgaat gatctatgga aatgatacaa accaaacgag tcgcattgta tattcgcgtg
     4681 agtacacaag aacaagcttt agaaggacat agtattcaag cacaagaaca aaatggacga
     4741 cagtttgccg aacggatggg ctatgaagtg gtagaagttt atgccgatga aggaatcagt
     4801 gggaaatcca caaaaaatcg gttcgcctat caacgaatga tgaacgatgc tcggaaccat
     4861 cgttttgatc tactagtgat ttggaaattg acccgtctcg gacgcaatat gttagatgtc
     4921 ttacaaacag tcgaggaatt attgcgatat gacgtaggat tacattcgat ctcggaacaa
     4981 tttgacgtga ccacttcgac aggtaaattg atgttacaac tccttgggag tttcggtgaa
     5041 tttgaacgca accaaattgc ggagaatgtt caaatgtcaa tgcaaagctt agtgaaagat
     5101 aaaaagcgtt atgcaggagg ccgacgttta ggctatgtca gtggtattga cacgaatggt
     5161 caaaaacaat tggtcattga accagaagag gcgaaaattg ttcgtctgat ctatgcaaaa
     5221 tatttaggcg gagcagggta tcgagcgatt gccaattttt tgaatcgtca aggatatcaa
     5281 acagtcaaaa agaatgcttt ttctaccacg gcagtcaaag atatcttacg caataaaatt
     5341 tatgcagggt atttagaata tgcgcgctac atcaattggg aaaccaaacg acggaagggg
     5401 aagaatccga gaccgatttt agtgaaagga acccatgaac cgattatttc ggaagaagat
     5461 tatcaaaaag tacaagaacg ccttgcttta gaaggaaaac aacccaaatg gaaccataca
     5521 ggtgaaaatg tattgacagg cttgttacgt tgtccagaat gtggcgcacc gatggcagcg
     5581 agtaatgtca caaataccct aaaggatggc acaaagaaac ggattcgata ttattcttgt
     5641 tcagtctttc ggaataaagg agcaagtgtg tgtcatgcca attcgattcg tgccgaacaa
     5701 gcggaaacat ttgtcgccga ccgattaaag gagatcgttc agctaccaga agttcttccc
     5761 cgattggtgg cagcgttaaa tgaagaaata gtgcgacaaa gccaaccatt ggaacaagaa
     5821 ctcgtggtgt tactggaacg aaaggaagaa ttgaagacta aaattgaaaa atgggaagct
     5881 gctttggaag atagtcctga attgtttccg atgttaaaag accgcttaga cgaattgact
     5941 gaaaaacgac gacagttgca cattcgagaa aatgaaatct tagggatctt tcaacaagga
     6001 gagccgattc aagtcaaaga tgtccaacgg atattgacta gtttggatcg ttttcttgcc
     6061 cagagtgaga agaagcaaat caaagccttg tatcgtacct ttatagagaa aataaccttt
     6121 gatcctaacc ataaggagat gttggaaatt acgatgaaat tcacgcatgc cgtggtacaa
     6181 caattgaatg agcaatatca aatagccgta tccaaaacaa aggatacggc tatttttgtg
     6241 ttaaaaacac cctttacgtt aacgatctag tctaggttat atcaaacaac gttagagggg
     6301 cgctaacgct tctctagcga tttgaaatcg ttagagaagt agttagggag gtccttatca
     6361 taaataggga tatttattaa tgaatatttg aaatataatt gtatataaga attaaaaaga
     6421 gtggggatag atatgaaaaa gatgggtaag tgtattttat gtgaaaaata cactgaactt
     6481 actaaagaac atgtaccacc taaaaaatca gggaatactg gaggtaaaaa gaccagaact
     6541 ggtaatttag atgatttcct taagagcgat tttacaaaag gtgattttcc gaaggggatt
     6601 aaaaggaaac ctcaaggaaa tgtttattat a
//
LOCUS       DADQCX010000118         6593 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.121, whole genome shotgun sequence.
ACCESSION   DADQCX010000118 DADQCX010000000
VERSION     DADQCX010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.121"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(31..978)
                     /locus_tag="J8R83_002490"
     CDS             complement(31..978)
                     /locus_tag="J8R83_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAZ9575601.1"
                     /translation="MSERISYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1156..1959)
                     /locus_tag="J8R83_002491"
     CDS             complement(1156..1959)
                     /locus_tag="J8R83_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAZ9575602.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2105..3019
                     /locus_tag="J8R83_002492"
     CDS             2105..3019
                     /locus_tag="J8R83_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAZ9575603.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3067..3537
                     /locus_tag="J8R83_002493"
     CDS             3067..3537
                     /locus_tag="J8R83_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAZ9575604.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3622..4230
                     /locus_tag="J8R83_002494"
     CDS             3622..4230
                     /locus_tag="J8R83_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAZ9575605.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4364..4564
                     /locus_tag="J8R83_002495"
     CDS             4364..4564
                     /locus_tag="J8R83_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9575606.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            5318..6544
                     /locus_tag="J8R83_002496"
     CDS             5318..6544
                     /locus_tag="J8R83_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAZ9575607.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         2228 a         1001 c         1317 g         2047 t
ORIGIN      
        1 tttttctttt gaaaatattg ttttcagcta ttaatatcct gcagacaatt ttacttgatt
       61 ggtttgaagc tcatgggtgg caaagtagct tttcagattg gttaaaaaaa tagccattaa
      121 tttcttttga aaatcaggtg tcaaacctgc aatgtgggaa gtaatcagta cattgtccat
      181 tttccaaaga ggatgatctt gtggaagagg ctcttcctca aaaacgtcta atgctgcaaa
      241 ggaaagttgc tggttattta aagcctgcac cagatcttgt gtcttaacag aagcaccacg
      301 gccaacattg atgaatacag attttggatc aaagtgttca aacatatgct gatcaaagag
      361 cccagttgtt tcctccgtta gaggtaagat attgactacg aaatctactt caggaagaac
      421 ttcctttagt tgatttaaag aaaaagtctt ttccattcct tctgctggat gaccggatgt
      481 attgattcca tagcagttca tgtctaatgc tttgcatttt tttgcaatca tttttccaat
      541 atggccagtt ccaatgatta gtattttttt cccttggata gattggtaat ggaccgatga
      601 acctaaccat ttcatgtcac tctgtgcctt ttgtgcttga aaaagaccac gagaataccc
      661 aaggatgatt cctaagacat gctccgtaat cgattcactg tggatgccac taccatttga
      721 aagtaaaata tgtttctttg aaaaagtctc aaggggtagc tgatcaacac cagctgagat
      781 agattggacc catttcaagg tagaagaggc taatagtttt tcttggtagt ctgagttcca
      841 gcccaaactg atctctacat tttgtagatc ctctggttgt aattctgttt taaagatata
      901 accaggcgct atagtatgga tttcttcgat aaattcatca cgaaatggac gatctgcata
      961 actgattctt tctgacatag ttaatttccc gcctttcttt actctaagtg tagcgcatac
     1021 aagaagaact ttgaagcgcc ttgcttgttt tttgagaaag aaatattttt caaataaaaa
     1081 aggggctgtg acaaaaaaat gtcacaacct ctaaaagggt ctattgaagt agaaataacg
     1141 agttgtcttt atttcttaat tgatcgatat ttttgcccat cctttgacag cttgagcaaa
     1201 aataaagatt cctgcaaaag caatgaaggc gctagtgtca aaagaaggaa gaaagaccat
     1261 caagattgtt gcaattatag taggcaatga aattgaatag atcaatgttt ttaaacaatc
     1321 aagaaaagta gcttttgtta gtcgaaagcg tgcatagaga aaagcagcaa tgttggtaaa
     1381 tagcaaagtg atcagcagat tcagaaaact aggataaata gaaaatataa atgtcaggac
     1441 ttttatccaa agtggtatag atgcttcact taaaaaagaa cggagctgct tacctgttaa
     1501 gttttttaaa gattcattgg tgtagggaag ttctaattgg ttattgttca acaaagcaga
     1561 agtcgtgcct gtattaggaa gagctatgat aagtttgttt tttaacatcc cgacactaac
     1621 aaaattcccc atcaaatcag tagagatgtc ctgttctgtt cgttttccct ctggatcaaa
     1681 tgtgaagata atggagtttg tttggtaaat gaatccttct ttttcttcgg tttgaagctg
     1741 cccgttttgg attgtaaaat caggaatgcg agtagcaatc ttttgcccat ccaattgaat
     1801 gttgtttaag acttgaaaaa cttgaaaaga gattggcaaa gccataatta tactcaaaac
     1861 taaaagatag acaatggctt tccaaaatgg gacatttctc gcctccttta ggtctttgaa
     1921 tcgtataaag gaactgataa ttaattgttt tgttgtcata agtactcctc atctagtagt
     1981 gtcatcactt gcaattctag cgaagtatca agtgaaatac aagtgcttta aggaaacagc
     2041 tgaatgattg gtgaaatatc aaaaaaatgt tattcttgtc taaagactat ccaatataaa
     2101 taaaatggag gaaggaatag tgcctacaca gccacagaga tcatcaaaaa aactatttgg
     2161 agtagtggtt ttgaatgcgg tgatcacttt atcagaattt attggaggga ttatgtcagg
     2221 gagtttgtct cttgtttcag atgctttcca taaccttagt gatacattgg caattatttt
     2281 ttcttacggg gcacaaaaaa tggcccgaaa agaagcaaat aaaaaacgta cgtatggcta
     2341 ccagcgttta gaaatattga gtgctttcat caactcattc atattgatca tattatcctt
     2401 gtttttaacc gttgaagcat tcaagcggtt cacttcacca gaaaagataa atagtcattt
     2461 gatgctaaca gtagcagtta ttggattgct cgcgaatttg ttctcagtat tattattacg
     2521 acaagaagca gatgaaagtt tgaatataaa atctagttat ttgcatttgt taagtgatac
     2581 actgtcttcg gtaagtgtga ttatcggagc aattttgatc cgttttttcg atatctactg
     2641 gatcgatcca gttattacac tgatcatttc gatatatata ttgatagaag cgataatggt
     2701 gatcaaaaaa gctgccgcta ttttgataca aagtgcacct gctatcgact atgaaaaaat
     2761 ggaacaagaa attgaagcaa tcgatggggt aaaggatgtt catcatgtcc atatttggca
     2821 gtatagcgaa aagataatta ttttcgacgg acatattgat tttgaagatc agctactaag
     2881 cgagattgaa aagatatatc ctcgtataat ttctttatta aaattaaaat atggtattac
     2941 acatgtgacg atccaagcag agacaaaggc aaaggatcaa aaaaaattaa tttttttaaa
     3001 taaagatgaa agttattgaa atatagagta tgataaataa gaatttttaa taaggtaggt
     3061 tggctcatga agcagtatcg acagttaaaa ggatatttag aagcaaaagg atattgggag
     3121 atactagtct atctcttttt tggtggtttg gctacgattg taaattttgt tagttttgct
     3181 ctcgcacgcc aatattttga tttaagtatg gccttatcca attctatttc gtggttttgt
     3241 tctgtattgt ttgcttttgt aacgaacaaa ctttgggtat tccattcaaa atcaccgaat
     3301 tttacacatg cacttattga atgcggtaag ttcttcttct accgtatcct ttcttacgga
     3361 ttggacatgg gggcaatggt attgttgatc aatgttatga acagcaatga gtatgtggcg
     3421 aaaatcatca ctcaaattat tgttatcctt gcgaactata ttttcagcaa gttgtttatt
     3481 tttaaagaaa ctgaggtttt tgaagaagaa gtaggtcaaa gtgaaaaaga cgactaggca
     3541 taacaattga agaatttcct tctctttgtt actctttgta atgtagacat tattaagaaa
     3601 acattgagga ggaatttttt tatgacttac acattaccag atctacctta tgcatatgac
     3661 gcattggaac cttatattga cgaagaaacg atgcatctgc atcatgataa gcatcacaat
     3721 acttatgtga cgaatttaaa ttcagcaatt gagaaatacc cagaattagg cgaaaaaaca
     3781 atagaagaat tattatctga tatggacgct attccaacag atatcaagac agctgtacgt
     3841 aacaatggtg gcggacatgc taaccattca tttttctggg aaatcatggc accaaatgct
     3901 ggtggcgaac ctacaggaga aataaaagaa gcgattaatg aagcttttgg tgatttttct
     3961 tcttttaaag aagaattcaa aaaagcagcc gctggacgat ttggttctgg atgggcttgg
     4021 cttgtaatgg aaaatggaaa attagctatt acctctactg caaatcaaga ttctccattg
     4081 atggaaggaa agacaccaat tctaggtttg gacgtttggg aacatgctta ttatttgaaa
     4141 tataaaaatg tccgaccaga ttatattgca gcattctgga atgttattaa ttgggatgaa
     4201 gtaaacaaac gtttcgaagc agcaaaataa ccatttcctc cgtcatatca gtcttaaaaa
     4261 taatttggaa aataaaagag cgaaagcttg ctagcgtttt ctaaattggg tataatgttc
     4321 ttgcaaggtt acttgcaaga acttttttgg aggatataca tttatggaac acggaacggt
     4381 taaatggttc aacaatgaaa aaggatttgg gtttattaca gtagacggcg gagatgacgt
     4441 atttgttcat ttctcagcaa ttcaaggaga cggcttcaag agcctagaag aaggtcaaga
     4501 agtagaattc acgattgttg aaggtgcacg cggacctcaa gctgctgaag tgactaaatt
     4561 ataataattt gttgaataaa gacacgactt cttagagagt cgtgtctttt tgtctattta
     4621 tgaagttttt agattttttg gctaagtaaa tgcatttgtt cacttgacat gtcctaacta
     4681 attatcaagc aaggaacatt ttcttcgtta gtaatggatt ttaaagaaat ttcagttttt
     4741 ggatgttgaa taaaagacca tttgtgaaac cactagtata catactcatt accatgtcaa
     4801 ttctattact ttaaaagaaa atcgttttac tttgaagagg agcatatcta tccattaaaa
     4861 gatgatggta atgcaatcac tagttcgagt cattttaaga gccatgcagt gagctggaaa
     4921 taaaacgaat agaagatggg tttaacaaaa ggaccagtca taggaagaaa ttgtcgtgaa
     4981 atcgaatgat aatctgaacg gtaggcaaag actgttaaaa agatgggaaa ggtatgtgcg
     5041 atcattttac tgcacgatta tttggaaaat accttgttgt tcgctttttc tggaaaaaat
     5101 acataaaaaa agataaaacg attgcgaact gcgtgtattc ggtctttcga tctttttcac
     5161 ggtatggtat gatagttaag aattttgaga aattttaaaa aataataatc gttacacaaa
     5221 aatgtttttt aaagttttct tatgattaaa aagtgaattt gctgattgaa cagttatatg
     5281 agacaatatt ttagaaaatg tgaaacagag gtgtattatg aagcgatggc aaaaagttct
     5341 attaaccttg ttaggggtat tcgttttgct gattgccgga ttatcagcat acggaatcag
     5401 atttatggga gaagcgagcc aaacagtaaa caaaatttct aaaaactcta atcgaatatc
     5461 ctccaaacgt tctgagagag taagcattga tgacaaagaa cctttttcgg ttttgctatt
     5521 aggtttagat accggtggat taggaagaac ggaacaagga cgttctgata cgatgatggt
     5581 agtaacagtt aatccgaaac aaaaaaaatc aacgatcatc agtttggacc gagatattta
     5641 tacgaatatc gtaggttatg gaacggtaga taaattaaat catgcctacg catttggtgg
     5701 tgtcgaaatg gccatggatt caattgagca actgctcgat attcctattg atcattatgt
     5761 aacgatcaat ttggatggca tggaagattt gatcaatgcg gtcggtggca tcaaagtgaa
     5821 taataaaatt gactttactt tggatggtgt ccatgtacca gtaggtgaac aaacattgaa
     5881 tggagaaaaa ggtttagcct attctcgaat gcgacacgaa gatccagaag gcgatatcgg
     5941 tcgacaacgt cgtcagcggg aagtagtgac gaaaatcgtc aataaagttt taagtttaga
     6001 tggcgtaagc aattatagaa aaattttaaa agcagttgag aacaatgtga cgacggactt
     6061 agattgggat gacatgcttg atgtagcgac gaactacacc ccggcgtttg aaacaatcaa
     6121 acaagaccag ttgcaaggcg aaggacaaat gatcaatgat atctactatc aaattttagg
     6181 aaaaaatgat cttctttcga tccaaaatga actgaagaaa caattaaata taaaaacaag
     6241 cgatacatta cctaatttga aaaatgagaa tgcttcaatg atgttctttg atgattcgga
     6301 agatggcgat tcgacaaacg gtgatggatc gaatagtgaa gggtacaccg attattcttc
     6361 ctattcagaa aacacatatg atcagtacca agatccgaat acctattatc agcaaacaga
     6421 agatacaagt cagtactata caccaagtca agatactcaa agttatgatc cttacgctgg
     6481 acaggaacaa aatggttatg gttatgacca gaataatgag tatggaacaa caagtgggta
     6541 ctagaaaaaa atagtttggt taataaagag tgccacctaa attagacaaa aaa
//
LOCUS       DADQCX010000119         6555 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.122, whole genome shotgun sequence.
ACCESSION   DADQCX010000119 DADQCX010000000
VERSION     DADQCX010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.122"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            63..1574
                     /gene="gadC"
                     /locus_tag="J8R83_002497"
     CDS             63..1574
                     /gene="gadC"
                     /locus_tag="J8R83_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HAZ9575608.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            1587..2987
                     /locus_tag="J8R83_002498"
     CDS             1587..2987
                     /locus_tag="J8R83_002498"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003134257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAZ9575609.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(3152..4587)
                     /locus_tag="J8R83_002499"
                     /pseudo
     CDS             complement(3152..4587)
                     /locus_tag="J8R83_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4980..5573
                     /locus_tag="J8R83_002500"
     CDS             4980..5573
                     /locus_tag="J8R83_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HAZ9575610.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(5557..6555)
                     /locus_tag="J8R83_002501"
                     /pseudo
     CDS             complement(5557..6555)
                     /locus_tag="J8R83_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2027 a         1102 c         1236 g         2190 t
ORIGIN      
        1 ataagcgatt ttccataacc ttggtaggaa tgacaaatta aataggaaag ggaagtaata
       61 atatgaataa aaaaaagtta tctctattcg gtttttttgc cctgacagct tccatggttt
      121 tgactgttta tgagtatccg acctttgcaa catcacaatt acatttggtt ttctttcttc
      181 ttttgggagg tattttatgg tttctaccag ttgctttatg tgctgcagaa atggcaacag
      241 ttgaaggatg gaaagatggt gggattttca gttgggttag tcaaacttta ggagaacgtt
      301 ttggttttgc agctattttt ttccaatggt ttcaaattac agtaggtttt attacaatga
      361 tctacttcat actaggagcg ctgtcgtatg taattaattt tccagagctt aatacagatc
      421 catttatcaa gtttattggt gtattagtca ttttctgggt actgactttt tcacagttgg
      481 gcgggaccaa tcgtaccgct aaaattgcta aagcaggatt tgtcattgga attgttattc
      541 cttcgatcat tctctttggt ttagcagcag cctactttat cggcggtaat ccgattcaaa
      601 tggctattaa tgcgaaagct tttattcctg acttttctca gctttcaact ttagtagtat
      661 ttgtatcttt tatattggct tatatgggcg tagaagcttc agcatcacat attaatgagc
      721 tggaaaatcc ccaaagaaac tacccattgg caatgttttt actagtgatt ttggccatcg
      781 ccttagatgc aatcggcggt ttctcagtag cagcggttat tccacaacat gacttgtctc
      841 tcagtgctgg tgtaatccaa acatttgaaa cgcttatttt acattttaac agtcatttac
      901 attggttggt aaaagtgatt gctctcatga ttgcctgtgg cgttatgggt gaagttagtt
      961 cttgggtagt tggtccatca cgagggatgt ttgcagctgc tcagcgaggt ctgttaccag
     1021 ttttcttccg gaaaactaat aaacaagacg ttccagttcc gttgattatg atacaaggaa
     1081 ttatcgttac tatttgggca gcagtcttaa cttttggtgg aggaggcaac aatttatcat
     1141 tcttagtagc aatctcctta actgttgtca tttatctcgt aggatattta ctatttttcc
     1201 taggttactt tgtattagtt tttaagaaaa aagacttaaa acgaacttac aatgtaccag
     1261 gaaaaactgt tggcaaaacg attatcggtg gaattggttt tattttatca gtgttcgcat
     1321 tgcttatctc ttttgtacca ccagcttcaa ttgcagctag tgagcaccga acataccaaa
     1381 tcatactact tattagcttt gtagtgactg ttcttttacc ttttatcatt tatgaagtac
     1441 atgataaaag tgctcacaca actattgagg aacctactca cgtgaaagct gaagacgtta
     1501 atcccgctgt ttatccagct gctagaggag agcaccacgt tacaaaaaat gatgaacata
     1561 ttttaaaaca ttaggaggaa ttcattatgt tatacggaaa agataatcaa gaagaaaaaa
     1621 actatttgga accaattttt ggctctgcaa gtgaggatgt tgacttgcct aaatataagt
     1681 taaacaaaga atccattgaa ccacgaattg cttatcaatt agtacaagac gagatgttgg
     1741 atgaaggaaa tgcgcgatta aacttagcta ctttttgtca aacgtatatg gaacctgaag
     1801 cagtgaaatt gatgacccaa acgttagaaa aaaatgcaat tgataaatca gaatacccac
     1861 gaacaacgga aattgaaaac cgctgtgtaa atatgattgc tgatttatgg catgctccaa
     1921 ataatgaaaa attcatggga acttcaacga tcggctcttc agaagcctgc atgctgggtg
     1981 gtatggccat gaaatttgct tggcgtaaac gtgctgaaaa attaggtctt gatattcaag
     2041 caaaaaaacc taacctggtg atctcttctg gttaccaagt ttgttgggaa aaattctgtg
     2101 tatattggga tgtggaactg agagaagtcc caatggatga aaaacatatg tcaattaatc
     2161 tagatactgt catggattat gtggatgagt acacaattgg tattgtaggt attatgggta
     2221 ttacttacac tggtcgttat gatgatatca agggtctgaa tgatttagtt gaagctcaca
     2281 ataaacaaac tgactataaa gtatacattc atgttgacgc tgcatcgggt ggcttttatg
     2341 caccatttac tgaacctgat ctagtttggg attttcaatt gaaaaatgtt atctcaatta
     2401 attcttcagg tcacaaatat ggtttggtat atccaggtgt gggttgggtc ttatggcgtg
     2461 accaacaata cttaccagaa gaattagtat ttaaagttag ttacttaggt ggagaaatgc
     2521 caactatggc tatcaacttc tctcatagtg cagcacaact aattgggcaa tactacaact
     2581 ttgtacgcta tggctttgat ggttatcgtg atattcacca aagaactcat gatgttgctg
     2641 tttatttagc caaagagatc gaaaaaactg gtatttttga aatcattaat gatggatcag
     2701 aattgccagt tgtgtgctat aagctgaaag aagatcccaa tcgcgaatgg acactatatg
     2761 atttatctga tcgtctgtta atgaagggat ggcaagtccc agcctaccca ttacctaaag
     2821 acttggatca attaattatt caacgcttag ttgttcgagc agactttgga atgaacatgg
     2881 ctggtgatta tgtacaagat atgaaccaag caattgaaga gttgaataaa gctcatattg
     2941 tttatcataa aaaacaggat gtgaaaacgt acggctttac tcactaaaat tcttcagaga
     3001 aatataaaag aagttaatta actaataaaa ggagttgtga ttaccacaca gctccttaaa
     3061 tctatttgaa taaatatatg atattcattt gttacactct caatcttagc tgttgttcta
     3121 ttcatcatta ctcttattgt aagtagttca gtcaaatttg cttgttcaat tgatcgataa
     3181 cagtatgaat tgtttgaaaa gtaatcggat atataattgt tttctcacta cctaagcctt
     3241 cttggtataa agaactatcg caaagtataa tccgctgagt acaaaagaaa gtgtcgtcta
     3301 ctatttctct aagttgttta caaatgatat tactaataga aaagtgttct cccaaaatgt
     3361 cttctaactg ttgtcgatag tataaatacc taaagtctga cggagctact atgaacactt
     3421 caattggaga tttccgttta tgctcattta aaagacttaa actaatggtt agtttacgaa
     3481 tagaattctc attccaacgc agaaataaat tgttttgttt tcgccattgt tcaagaattt
     3541 catgaacttc taagtacaaa gcgcgttgct cttcatttaa caagtaagtc ttatcaggtt
     3601 gaaatatctg aatatcagcc caaagtgagc ggataaacgg gagaagtgct ttatcaaaaa
     3661 gtatctgatt ttcttcagat atattcagag ataagataag tttttgactg agctcaatca
     3721 ccaaagggtt atctgctaca tggttttgat aaacaacgtt caagtctttt tgtaacaatt
     3781 caaagttatc gcatagataa tttctagagt tgaatagaaa gtagatataa aggcattcat
     3841 cttcgtcatg acataaagag aaagaaagtt gctctaatcc tttctgtatt agctgaaaca
     3901 agggagtatg tcgggcaact cttttttctt cctgactaaa atatattggg ttagtcttag
     3961 atctctgcaa accgatagcg atacctaata aaataaattg tttttcaact gtagggtaac
     4021 ttcttgaaaa aaatgttttt ctacataatc aatcaattgt tgaccgcttt gaataattga
     4081 tttatttagc tggatcaact ctgtccgatt tgtctcatag attatcgtta gtaacaaact
     4141 tcgataatcc ttttcaggaa tttcaaaatg gccatcagca tttaagtact gcatttgttt
     4201 aaaaaaatta atcaactcat ttcgtaagtt gtaaactttg cttaacgaaa tgaaggtagt
     4261 atcagctata ttactccaat tgtgttcccc tgataaataa tgtcctagta cattgaaaaa
     4321 gtcagagcgc tgatagatga gttgagtgag tgccaacctc gaaaacgaag agtcgaatgc
     4381 gactgtaaag ctacttctag atttctccac tgaaataatt tgctgatgga gtatgtcggt
     4441 aatgcattcc aagtcgttag tgacagtgag tgggcaaacg ttcaattgat ctgctatttc
     4501 gcgaatctga atggtccctt tttcgtgtaa ttgctcacaa atgtaaactt gacgaaaaat
     4561 acttttctcc agataggttt ccaacatagt actcctccta gtcattttat acataactat
     4621 tataactcta ccaatcggaa tagtcctgta atatattgaa tcaaaaatat aaattataaa
     4681 ataattagat ggggtatttg gtttaagtat cccttatata gtaataaatt tataggtgtg
     4741 attctcgaat taatacccga aaatgtgaga gaatttttat ggatttttta ggatacaaat
     4801 taattatttt tgcttttatc ctgattacca gtccagtact gtcggtatcc cattttgcag
     4861 caaaatcatg ttgataaagt gacaagaaga ctgatgagat atattatcca aattgagaag
     4921 ataattaatc ggattcttga gtatacccta ctttttaaga aagtagggta tacaagcgta
     4981 tgaataaaga cataactttc cctgtgatgg acgttcggct tgttccaatt accaaaatac
     5041 aggcgaacga ttataatccc aatcgagtag cgtctccgga aatgaactta ttggagcttt
     5101 ctatcattga agatggcttt actcaaccat tagtttgtta ttacaaggaa aaagaagaga
     5161 agtatatctt ggttgatgtg cttcataggt atcgtgttgc taaggaaaga ctcaacttaa
     5221 aagttgtacc ggtaacagtt attgataaac ccatagaaga acgtatggct tcaacaattc
     5281 gacacaatcg tgcaagaggg acccatgaaa taagaggaat ggaaattgtc atccaaagat
     5341 tagtaaaaaa tggatggtca gacaagagaa tatccaaaga attaggcatg gacattgaag
     5401 aaatttttcg ctttaagcaa gtgtctggtg gaatggcaac agtttttttg acaaatttta
     5461 taaggtgcag aacttctttc cgtatgctat tccgattgtc cttgacaatg agcctcctcg
     5521 gatgtgacga tcttcggcag gagctaacag ttaaagttag actgcctcgc tagcgttagc
     5581 acatccgagc tcattatcaa ggattcgctg cgccaatctc tggttacggt aaccaaccgg
     5641 tgtctcgtag ccaagtgtac cgtgcaaccg aaggtggttc caccaattta catagtcaaa
     5701 taactccaaa tccaattgtt gtaaggtttc aaatgtgtat tgatagacaa attctacttt
     5761 caacgactta taagttgatt cagctacggc attatcaaaa ggacagcctt tatgactcaa
     5821 tgatcgattg atgtcaaaag ttgttaataa ttcatcaata gcttggttat caaactcttt
     5881 tccacgatca gtatgaaaaa tctcaacctc tgtcagaggt tgtttgatac ggctaaatgc
     5941 tttttttact agaacggcat ctttatgttc tccacaagaa tagccgagaa tttctcgatt
     6001 gaacagatcc aaaatgaaac agacataatt ccattttttc ccgactcgta cataagtcaa
     6061 gtctgttacg atcgcttcta atgggttgtc tcttaagaat ttacgattca atacgtttgt
     6121 cgttttggct tcattgcaag tagaatgatg tactttaaaa taagcaacag tatagctcga
     6181 ttttaatcct ctatttttca tgattctact aatttttcgt cggctgatct gaatgcctcg
     6241 ttttgataag gcttttttta tttttcttga gccgtaggcc tttcggctgc ggataaattc
     6301 ttcagcgact acttcttcaa gttctgattc gtctttcttt ggttttgatt gataataata
     6361 ggactgacgt gatagaccta atattctgca catcgctgat atagggtaaa gatgcttatt
     6421 cgcatcgatt acttgtctct tcgtccgaat atcagcgctg cttgctttaa aatatcattt
     6481 tccatttcta attgctggtt tcttttacgt agttctaaca attctttttg ttcaggcgta
     6541 agattatctt tttct
//
LOCUS       DADQCX010000120         6173 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.124, whole genome shotgun sequence.
ACCESSION   DADQCX010000120 DADQCX010000000
VERSION     DADQCX010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.124"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            725..811
                     /locus_tag="J8R83_002502"
     CDS             725..811
                     /locus_tag="J8R83_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAZ9575611.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="J8R83_002503"
     CDS             complement(932..1621)
                     /locus_tag="J8R83_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575612.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="J8R83_002504"
     CDS             complement(1628..1906)
                     /locus_tag="J8R83_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575613.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="J8R83_002505"
     CDS             complement(1866..2780)
                     /locus_tag="J8R83_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAZ9575614.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="J8R83_002506"
     CDS             complement(2762..3142)
                     /locus_tag="J8R83_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAZ9575615.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="J8R83_002507"
     CDS             complement(3592..3879)
                     /locus_tag="J8R83_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9575616.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="J8R83_002508"
     CDS             complement(3899..4123)
                     /locus_tag="J8R83_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAZ9575617.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4763..5296)
                     /locus_tag="J8R83_002509"
     CDS             complement(4763..5296)
                     /locus_tag="J8R83_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAZ9575618.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="J8R83_002510"
     CDS             complement(5317..6159)
                     /locus_tag="J8R83_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAZ9575619.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DADQCX010000121         6072 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.125, whole genome shotgun sequence.
ACCESSION   DADQCX010000121 DADQCX010000000
VERSION     DADQCX010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.125"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..660)
                     /locus_tag="J8R83_002511"
     CDS             complement(<1..660)
                     /locus_tag="J8R83_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9575620.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            844..2490
                     /locus_tag="J8R83_002512"
     CDS             844..2490
                     /locus_tag="J8R83_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAZ9575621.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            2481..3563
                     /gene="uxuA"
                     /locus_tag="J8R83_002513"
     CDS             2481..3563
                     /gene="uxuA"
                     /locus_tag="J8R83_002513"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAZ9575622.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(3671..5224)
                     /locus_tag="J8R83_002514"
     CDS             complement(3671..5224)
                     /locus_tag="J8R83_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9575623.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            5372..>6072
                     /locus_tag="J8R83_002515"
     CDS             5372..>6072
                     /locus_tag="J8R83_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9575624.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDV"
BASE COUNT         2007 a         1068 c         1147 g         1850 t
ORIGIN      
        1 ctgctggaaa tactcgggat aacgttgagt aacagtttcc tgttctttca gcatcatgtg
       61 taagtgcaat cccgtttgaa atcgagcttc ttctggtttt ttatcaacta aagccttgag
      121 taaatcataa tgttgttcca tgatcgtttc ccatggaagc ccctgaatgg tcactcgtaa
      181 ccagcggaaa cgttctaaat gggtattatg gtcatctaac cagttccaaa cttcttttct
      241 tcctgcaatt tcgaaacaag cttcatgaaa taaattatct gcacggaaaa aagcgcgttc
      301 gtcatttatt ttgactgctt tttcttgttc ttctaaaatc gtttctagca ctattcgtgt
      361 ttgtgtgtcc aatttggaac aacattcaat catgatttgc tcttccaact gttctcggac
      421 aaagcgagca ttttctgcag aaacaagatt aattttggaa acatacgtac cactttgagg
      481 tatcgtatac acgagttctt gctgacgtag ttgaatcaat gcttcgcgaa tgggagtccg
      541 gccgatagca agatgttcct ccagtgcctt ttcagatatt ttccttccag gttctaagtc
      601 agcatagata atttgtttac gaatcgcttg ataagcttgt gattgcaagc tgcttttcat
      661 ctttattcct ccaaaatcat ttctatgaac gtagtataac agaagaggtc tgaaaaacaa
      721 tctggtatgt cacattaact agtaaatttg tataaatagt aaaattttgg ttgacatagc
      781 gatttttatt gtataaaatt cacttgaata caaaaactaa tatgttagtt taggagggga
      841 aaaatgattg atttaaacaa ctggaggaac tttatccctg aattatctca aaaagaagta
      901 gaaatacctc attttgaccg tgcatcatta agagaaaatg gacaaaaaaa tcctgtctgg
      961 atccatttcg gtggcggaaa tctttatcga ggatttcatg cagaaatcgc tcaacgttta
     1021 gcggatctag gcgaattgtc cactggtgtc attgtttgtg aaacattcga tgaagaaata
     1081 attgaaaggg cttaccaaga ttttgatgat ttgattcttg aagtggtcat gccaagcagt
     1141 ggagagttcg tcaaacgtat attagctgcg acagctgaca gtctgtattg tcatccagat
     1201 tgttctgaac actttgataa gatgattcga cactttgaaa atcctagttt acaattagtt
     1261 acttttgcta ttactgaaaa aggttatcga ttgaaagata caaataataa atatatagga
     1321 ccgattgcag tcgatataaa aaatggtcca aagaagccat cacatacaat gagtattctt
     1381 gctgcgctac tttataaacg ttttttatct ggagcttggc cgattgcact tgtctctaca
     1441 gataattttt cacaaaacgg tagtcaatta cgtacttctt tgctaacgat cgcaaaagaa
     1501 tggcaaaagg aaggttatgt acaaaataca tttatccaat acttatcgaa tgaagaaatt
     1561 gttgcgtttc catggacgat gattgatcgt atcaccccga atccttcctt gtcagttagc
     1621 aaaatgttgg caaaagaggg cttttcaaat atgtcgattt tccaaaccgc aaaaggaaat
     1681 aatattgctc catttgtcaa tacagaggac atccattatt taatcatgga agatcatttt
     1741 cccaatggac gtccgaaatt cgaaaaagct ggggtattct tgactgatcg tgcaacggta
     1801 gataaagcag atacgatgaa ggtgacgact tgccttaatc ctttgcatac gtctttagct
     1861 attatgggtt gtttactggg gtataggagc atagctgagg agatgaaaga tccagattta
     1921 tcgctgctag tttctgaaat cgggtacaat gaaggcctcc cagttgtgga gtctccaggt
     1981 atcattgatc caaagatctt tctggaagaa gtaattactg tgcgcttttc taatccaaat
     2041 attcctgata tgcctcagcg aatcgccacg gatacctctc aaaaggtggc gattcgttat
     2101 ggtgagacga ttaaaaaata tatggaaata gaagttaaag acccgcagac acttgtattc
     2161 ataccattga ctctcgctgc ttggcttcga taccttattg gcattgatga tcaaggaaaa
     2221 ccattcatcc cgagtccaga cccactattg acagactttc agcataagct ttccgatatt
     2281 caactgggta cgcaagatac atcacatatt catgagaaaa tggctcctat tttgtcaaat
     2341 aaagaaattt ttggtgtaga tctttaccaa gcagagcttg gcagaaaaat agaagaaatg
     2401 ttcatcaaga tggtagcagg accgaatgcc gtacgaaaaa cattacagga ttacttacaa
     2461 gaacatggag gaaatttatc atggaaatga cttttagatg gtacggatca caggaagaaa
     2521 agattacctt agatgaaatc agacagattc ctgcggtcaa agggattgta ggcacattga
     2581 tggatatacc agtaggagag gtatggccca gggagaggat caaagaacta aaagaagaaa
     2641 ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt caatgtgcat gatgccatta
     2701 aaattggatt accttcccgt gagcagtata tcgaaaacta taagcagaca atccgaaact
     2761 tggcagaata tggaatagaa gtcatctgct ataattttat gcctgtattt gactgggtga
     2821 aatctgacct tgactaccgc ttagaagacg gctcatccac gttagctttt atatctgatg
     2881 atattccaga tgatccaaga gaaatcgtcg cgcgcatcga acattccagc aatgaatttg
     2941 aattgccggg atgggaacct gagcgcttag ctcatatcaa atccttgctt gaagcctatg
     3001 catcagtaga cgaagaaaaa cttcgagaaa attttgccta ttttctccaa tcaatcatcc
     3061 caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc agatgatccg ccatactcga
     3121 tttttggatt acctcgaatc gtaaagaatc gagaagattt agattggttg tgccgcatag
     3181 tagacagccc ttataacgga atcactcttt gtacagggag tattgcagaa gatccagaaa
     3241 atgatgtata tgggatttta gcagaatttt gtcaaagaga tcgaatccca tttgcacatg
     3301 ttcgaaatat taaattttta gctaatcgag atttctatga ggcaccgcat aaatccgaat
     3361 acggttcatt agacatgtac cgcatactaa aaacaatgta tgacaacgga tttaacgaat
     3421 acatccgtcc tgatcatgga agaatgatct ggaatgagac aggaagacca ggatacggct
     3481 tatatgatcg agcattaggt gctgtttatc taaatggatt atgggaagca atcgaaaaag
     3541 gaaacaaaag taaagataat tagtgaaaaa aactgtaatt ttattatgta aataagaagg
     3601 atgttcaaat tcttgataca taaatccgga ggttgttaat aagcattcgg atttatgtat
     3661 cttatttggt ctaggaagta acttgatttt cttttttcga ttgatccatg agtgcttctt
     3721 cttttaattc aaagatatat tctgagatcc tcataatcac ttttttccag tcttctggtg
     3781 tgatgattcc ttttaaaata tagatttttt tgatatgaga aggcaattgt ttcaaagggc
     3841 agtcgctgat aacgatgttg cagttctcca taaaatcatt ttgtattttg atcgattcat
     3901 ttgaaaaaat ttgttctatc ttaacgatca gatctttact gatataaaaa tcacgcgtat
     3961 agttcacacc aatcacaatt cgcggctgtt ttttgtagcg atcatacaaa tgtactaggt
     4021 cttcaaccat ccattgcaca ttttcctttt ctaaaataac tggtaacaag tgttgatttt
     4081 gttctctgaa atccatataa aattgttcaa tggcggtttg gacttctttc aacacgctat
     4141 gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg ttgattgaag ttaagaaatc
     4201 cattataaag tttatttcgt gcgaatgcca atgagtaaag aatcttttct ttttcaggta
     4261 taaacaaatc aaatacagta caaaaggact ccaccatttc tcttgaataa agaacatgag
     4321 gaacgtttgc tttttttaaa agtttgtatt gctccaagct tgtttcttcc gattcgattt
     4381 tcgtgataga aagtcgagct aaaatattca ctaagatgcg ttgttcgcga caaattggca
     4441 gattaggtcg caaaatatct acagagggat caataaaaaa gtcaatatat tcatactctg
     4501 tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa attctcttta catattttta
     4561 atagaaaata taatttatct atcataccgc tatttagtcg gtcaagtact tcttttttaa
     4621 aaaaagtatt catcataaaa gccactactt gcggatcttc atcataaaat tctgtagcag
     4681 tacttgaaaa gatgttccaa taaatatcta atgctgcata ttgaatttgt acctcttttc
     4741 cagaaaaaga ctttctgcca ttattagaaa aggagataga caaaccgtac aatgctaaaa
     4801 atgcattaat ctttttcatt ttcgtataca aataagaggc actatagttt gtttgctgac
     4861 ttaaactgat aatcgaattt gtctgacagc tgaacaaaga agtcaagatc tgataactga
     4921 ctgattcgtt gcagtatctt ccaaatagac gataatagca gtaagccgga tcaattcctt
     4981 caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg cagttctgtt agattgagac
     5041 gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa atttgattca gacatatgga
     5101 aatgatctgc taaatattgt gtagtaataa agaaacgatg ttcagatagg aaaagaaaaa
     5161 tatctaattt tgtattgctt tttttcttca agagaaacgt tttaatcgct tcttgagttt
     5221 gcatgaaaga ggctcctttt tacttaaatt gttaaaactt gaaaatatta ctgttttttt
     5281 cataaattta gacaaaaaaa cagtaaacat ataggtagaa tctctactat cttatttctt
     5341 gcatacaaaa aaatcaagga gtgagagagt tatgagatat tcaaccatct taatatcaac
     5401 atttgcagcc ttaagcttat cgcttactat aaatcagaca gtccacacag aggagataga
     5461 aacagccaaa tggacagaaa ccaagtgggc caacgtcaat cgaattacct ttcaggatga
     5521 attttcatcc ttcaattcag gagtcgcaaa attaagaaaa ggacaaacag cgaccatcaa
     5581 agcaaaaatt gactattcag gagacttagc acctatacta caatcagctg ttacatttga
     5641 gaatgttgat cccgctttgt cgattggcta tgacgagaac actttgacta tccaacacaa
     5701 gcaagcgata tttaccttca ccgttacatt aaatcaggac ttgttaaaac cagcgctttt
     5761 tactgtcaag gtatcagatg gactaccgaa cgatcatcat catttaacgc cgtatagtca
     5821 gcggcagaca attgagcaag attcagctat cgactcagga ggagatcttg ttgaagaacc
     5881 aacagataaa ccagaaaatg aaaataagcc agaagtaccg cctacagaaa atccagacgg
     5941 agaacagaaa ccggaaatag aacctggaga agaacccgat acagaaactc aaccagagcc
     6001 agacaatgaa tcaaaacctg aaataacccc tggagaaaaa ccagatgtag acccagaaga
     6061 aaaaccagat gt
//
LOCUS       DADQCX010000122         6058 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.126, whole genome shotgun sequence.
ACCESSION   DADQCX010000122 DADQCX010000000
VERSION     DADQCX010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.126"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            292..2523
                     /gene="pflB"
                     /locus_tag="J8R83_002516"
     CDS             292..2523
                     /gene="pflB"
                     /locus_tag="J8R83_002516"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAZ9575625.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            2767..3528
                     /gene="pflA"
                     /locus_tag="J8R83_002517"
     CDS             2767..3528
                     /gene="pflA"
                     /locus_tag="J8R83_002517"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAZ9575626.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            3613..4539
                     /locus_tag="J8R83_002518"
     CDS             3613..4539
                     /locus_tag="J8R83_002518"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAZ9575627.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            4721..5614
                     /locus_tag="J8R83_002519"
     CDS             4721..5614
                     /locus_tag="J8R83_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAZ9575628.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            5748..5873
                     /locus_tag="J8R83_002520"
     CDS             5748..5873
                     /locus_tag="J8R83_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575629.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
BASE COUNT         2143 a         1022 c         1195 g         1698 t
ORIGIN      
        1 ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga cgccatctgt attaatacag
       61 gtggcgtctc tttttcattc atttttaata aatccttata cgtttgcaaa aaaagatgaa
      121 agtgttcaca atgcttaaat gttggtatgt caacgttgat ttaaatatat gtaaataaaa
      181 cataaaaatt gttaaataaa aaacaagaaa acccttgcaa agatagggtg ctgtgttata
      241 ctaatcacgt aaaaactgtt acataaaaca gaaatttagg aggtccatac aatggagcaa
      301 tggaatggat ttaaaggtac caaatggaaa gaaggcgtag acactagaga ctttattcaa
      361 aataactaca ctgaatatcg cggtgatgac agctttttgg aaggcccaac agaagcaaca
      421 gaaaaattat gggatgaatt gcaaaagtta aatgatatcc aattcgagcg taacggtgtc
      481 tatgatatgg acacagaaat cgtatcaact attacttcac acgatgcagg ctatttggat
      541 aaagatttgg aaaaaatcgt cggtctacag acagacaaac ctttgaaaca agcattcatg
      601 ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa gcaatggcta tacaccaaac
      661 gatgaattga cacatatttt cactgactgg cgcaaaacac ataatcaagg tgtatttgac
      721 gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa tcattacagg gcttccagac
      781 gcttacggtc gcggacgtat catcggtgac tatcgtcgtg tggcattgta tggaatcgac
      841 tatttgatgg aacaaaagaa aaaagatcat gatatgactg gttatcatac aatgagtgaa
      901 gaagtgattc gtttacgtga agaaatcact gaacaatatc gtgcattagc gcaaatgaaa
      961 gaaatggctg cgaaatatgg ctatgatatt tctaaaccag ctgcaaatgc aaaagaagct
     1021 gtccaatggc tatacttcgg atatttagca gcaatcaaat cacaaaatgg tgctgcgatg
     1081 tcaatcggac gtatctcagc attccttgat atctatatcc aacgtgattt ggataatgga
     1141 gtaatcacag aaaaagaagc acaagaattg atcgaccact tagtaatgaa attacgtatg
     1201 gtcaaattcg cgcgtacacc tgaatataac caattattct caggattccc tatctgggct
     1261 actttatcca ttgcaggtat gggattagat ggtcgttcat tagttacaaa gaatgatttc
     1321 cgtctgcttc atacattaac aaatatggga ccttcaccag aaccaaactt gactgttttg
     1381 tattctgaac accttccaga aggattcaga acatatgcta gcagaatcgc tatcgaaagt
     1441 tcttcgattc aattcgaaaa tgataatcag cttcgtgaac aatggggttc tgatgattgt
     1501 gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag acatgcaatt ctttggcgct
     1561 cgtgctaact tggctaaaac actattatat gccatcaatg gcggagtcga tgaagtgact
     1621 ggcgcccaag ttggaccaga atatcgtcca atcacatcag aaatactaga ctttgaagaa
     1681 gtgaaacata acttcatgaa tatgatggat tggttagcag aactatatgt caatacgttg
     1741 aacatcattc attatatgca tgataaatat tcttatgaag cagctcagct ggctttgatg
     1801 gattctgact tgcaacgcac atttgctaca ggtattgctg ggatctctca tgcggcagac
     1861 agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc gtaatgaaaa aggaatagca
     1921 gttgattttg aagtggatgg cgacttccct aaatacggaa atgatgatga ccgtgcagat
     1981 gaattagttt catggatctt ggaatacttc atgggacaaa tcaaacgtca taaaacttac
     2041 cgcaactcaa aaccaacaac ttcattattg acgattactt caaatgttgt ttacggtaaa
     2101 aatacaggaa atactcctga tggccgtgaa gctggaaaac cacttgcgcc aggagcaaat
     2161 ccaagttaca atgcggaaca aagtgggtta ttagctagcc tgaactcaac agctaaaatg
     2221 aattacggct gtgcattgga tggaatttca aatacccaaa caatcaatcc ttcaggtctt
     2281 ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg tcttagatgg atacttctca
     2341 aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg atttattgcg tgatgcaatg
     2401 gaaaatccaa tgaaatatcc gaacttgacg atccgggtat ctggttatgc agttaaattc
     2461 cgtgacttga caagagaaca acaattagat gtcttgatga gaacttcaca cgacagaatg
     2521 taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa aggacgttga atagccatcg
     2581 catcaaaatc gaataatcag tatgcttatt tgaaagaaac gatttacagg ggcaggactt
     2641 gtatgttccg tccctgtaaa ttttacacat aacgaagcgg caattgcgaa aaattttgtt
     2701 cagaaagctt cgcttcgaca gctaacttgt acttaaaatg aaatcaaaga aaagatgtga
     2761 acttaaatgg aagaaaaaac aatcggctat gttcattcta tcgaaacttt cggttcagta
     2821 gacggacctg gactgcgctt tgtcgtgttt atgcaaggat gccgcatgcg ttgccaattt
     2881 tgtcacaatc cagatacttg gaatattggc ggagggaaag aatacacagc agatgaactt
     2941 ttagataaag cagaacgctt cagaccttac tggggagata aaggtggtat tactgttagt
     3001 ggtggagaac ctctattgca gatcgatttt ttgatcgaac tatttaaaaa agcaaaagag
     3061 cggaagatgc atactacatt ggatacatgc ggaaaacctt ttacgtatga agaacctttc
     3121 ttttcacgtt ttcaagaatt gatgaagtat acagatttac tgttatttga catcaaacac
     3181 atcgataatg aagagcataa aaaactaacg cattgggaca atgaaaatat tttagaaatg
     3241 gctcaatatt tgtcaaaaat caacaaaccg gtttggattc gccatgtact agttcctgag
     3301 cgaagtgatt atgatgaata tttgatccga ctagacaact ttattcaaac cttgtcaaat
     3361 gtagacagag tagagattct tccttatcat acgatgggaa aatacaagtg ggaaacactt
     3421 ggtttgaaat atccattaga agggatcgaa ccacctacaa aagaacgtgt cgaaaatgct
     3481 aaacgattgc ttcatacaga agagtataca aaatatttaa cgcgataggt cgcatcggaa
     3541 agaagataag tattgcttct ttccgttttt ttgctattat taaataggag aaatcacaaa
     3601 ggagcgaatg acatgtcaaa aattttagtt tttggtcacc aaaatccaga tacagatgca
     3661 atcggggcag ccattgcgtt ttcacacttg caaaatgaat taggtaaaga aacagaagca
     3721 gttgctctag gtacacctaa tgaagaaaca caatacgcat tagaccactt tcagctatct
     3781 gcaccacgag tagtagagtc agctaaagca gaaaatgcag atgtcatgct tgtggatcat
     3841 aatgaattcc aacaaagtat ttcagatatc agcgaagtaa atattttagc tgtagtagac
     3901 caccatcgta ttgcaaactt tgaaacagct aatccattgt actatcgtgc agaaccagtt
     3961 ggatgtacaa gtacgattat tttaaaacta tataaagaaa accaagtaac aattcctaaa
     4021 gaaatcgcag gaatcatgct ctcagctatc atttcagata cattgttgtt caaatcacca
     4081 acatgtacgc ctgaagatga agcagctgca aaagaacttg cagcaatcgc tgaagtcgat
     4141 ctaaacactt atggacttga aatgttgaaa gcaggaacaa atctaagtga taaatcagct
     4201 gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg gcagttccaa cgttcgtatc
     4261 gctcaagtca atacagtgga ccttaatgaa gtgatggatc gacaagcaga gctagaagca
     4321 gcaatggaag atgaaatgaa agcaaatggc tacgatctgt tcgtattagt tgtcacaaac
     4381 atcttagaca gtgattcaga attacttgtt gctggtaaag gaaaagaaaa agtagaagaa
     4441 gctttccaaa caactttgac caacaaccgt gctttgctta aaggtgtcgt ttcacgtaaa
     4501 aaacaagtcg tacctcaatt gacggctgta tttagctaat caaatggtag tatgaagcat
     4561 tcaaaatgaa tggataagcg attgatataa aaagaaacat agaacatact aaaggccgaa
     4621 gaaatggagg agaataacag tcaattatga ctcttgttct tcctcctttt tacgtaaaag
     4681 ccttttaagt aaaataaaac ggatagaaaa gagaacatat atgaactatt attcaaaaaa
     4741 taaggaaaac ttttatcaaa aactgaccga tgatccgctt ttttcttcat tgaccgatta
     4801 tctatatgaa catcgagaac aagaaacgat tctaagagaa ttgaaaaaag aattttcgca
     4861 aaataaattt tcccattttc ttgatttatt gatcgatgca ggattaatca agagggaaga
     4921 acgaagatat catttgaact ttccaatatt tgatcctaaa gattacttgc aacaagccac
     4981 ttcggctgct gaaaccatag ctgaacaatt gaagagactc tctgttgatg aacaaaaatt
     5041 agcgatggga gaagttattt gggcgtattg tttcgaagat gaacggaaag aagcgtattt
     5101 ttatggagta agaaacagcc gagagacaga attgctgagg acaactgcag gaaatgagaa
     5161 gtaccgtttt atcacacttt cctctataga acacttcccg cttactttgg ctaattactt
     5221 ttttgtacag aagaatcagc ttcctgtaac gaaggcattc aaagaattag ccgaacttat
     5281 tggagacgta aatgaatcgt acttttttga tcaaatagaa gttatcgttg acaggatacg
     5341 taagaataaa tataaaaatc gccggcctag tattttccat cagtctctac ttgtgacgaa
     5401 tactataaag gaagaagaat cattcacatt agaattacct attgtcgaaa aaaacaattt
     5461 tgagattgaa ttaccaacat tggatccttc attgacaatg gaggaaatgg cctttcttaa
     5521 acgacaaatc ttttctgagc tgagcaagaa atttataccg catgcatttt cttatatcaa
     5581 agaatatgga acagttttag tgagtaaaac ctaagagagc agtaagcaaa aattatactg
     5641 actcttgcag gaggagcctt tctcttcctt tatggttaaa agaattattt gagtattttg
     5701 cctatctacc acctattaga ttcactacat ggtctggaaa caaaggaatg caaaaaaatg
     5761 gtgagaaatg tggaatgaca aaggaagtag tgataagaaa agttagattt ttaaataatc
     5821 aatattatga ttcagtcaag tatggcattt tatgggaaga actagctgat tagattagga
     5881 agtccatttg ataatccaga atcactaaga aacgaatggc gagtcattaa taatttatcc
     5941 aatcttgggt tattctttta gattgaagtg tttaaaacta aaaaagcatt tatgaagtcg
     6001 taatagtcag gcttcaaaat gctttttatt ttgtttgttt tttctttgcc acataaat
//
LOCUS       DADQCX010000123         5959 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.127, whole genome shotgun sequence.
ACCESSION   DADQCX010000123 DADQCX010000000
VERSION     DADQCX010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.127"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..450)
                     /locus_tag="J8R83_002521"
     CDS             complement(<1..450)
                     /locus_tag="J8R83_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9575630.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="J8R83_002522"
     CDS             674..1465
                     /locus_tag="J8R83_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9575631.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="J8R83_002523"
     CDS             1431..2384
                     /locus_tag="J8R83_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HAZ9575632.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="J8R83_002524"
     CDS             complement(2782..3756)
                     /locus_tag="J8R83_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575633.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="J8R83_002525"
     CDS             3871..4305
                     /locus_tag="J8R83_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9575634.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5416)
                     /locus_tag="J8R83_002526"
     CDS             complement(4430..5416)
                     /locus_tag="J8R83_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HAZ9575635.1"
                     /translation="MEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGAFFRVHHFAPQIG
                     SPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQGRVQLGVGRGSPE
                     QVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPMFPQGSGKLRIEP
                     YSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQQANQLRAYKEAW
                     KQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYHRNPTIFGKTFAG
                     EPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIAPELGWR"
     gene            5844..>5959
                     /locus_tag="J8R83_002527"
     CDS             5844..>5959
                     /locus_tag="J8R83_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HAZ9575636.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGI"
BASE COUNT         1872 a         1124 c         1026 g         1937 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttattg ttctactaag ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact ttcatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc atctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taagaagtgc ggggatcga
//
LOCUS       DADQCX010000124         5877 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.128, whole genome shotgun sequence.
ACCESSION   DADQCX010000124 DADQCX010000000
VERSION     DADQCX010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.128"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            641..1375
                     /locus_tag="J8R83_002528"
     CDS             641..1375
                     /locus_tag="J8R83_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9575637.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="J8R83_002529"
     CDS             1391..2560
                     /locus_tag="J8R83_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9575638.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="J8R83_002530"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="J8R83_002530"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAZ9575639.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="J8R83_002531"
     CDS             3650..4576
                     /locus_tag="J8R83_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAZ9575640.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="J8R83_002532"
     CDS             4595..5845
                     /locus_tag="J8R83_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9575641.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1968 a          955 c         1203 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacaac aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DADQCX010000125         5861 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.129, whole genome shotgun sequence.
ACCESSION   DADQCX010000125 DADQCX010000000
VERSION     DADQCX010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.129"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            237..1628
                     /locus_tag="J8R83_002533"
     CDS             237..1628
                     /locus_tag="J8R83_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAZ9575642.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            1687..2490
                     /locus_tag="J8R83_002534"
     CDS             1687..2490
                     /locus_tag="J8R83_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9575643.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2523..3377
                     /locus_tag="J8R83_002535"
     CDS             2523..3377
                     /locus_tag="J8R83_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HAZ9575644.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3374..4075
                     /locus_tag="J8R83_002536"
     CDS             3374..4075
                     /locus_tag="J8R83_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HAZ9575645.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4083..5150
                     /locus_tag="J8R83_002537"
     CDS             4083..5150
                     /locus_tag="J8R83_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAZ9575646.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5143..>5861
                     /locus_tag="J8R83_002538"
     CDS             5143..>5861
                     /locus_tag="J8R83_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9575647.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEEKYFYLQRNDSIMGKSFSM
                     NNFDVIEAWQYNKEKILDAFP"
BASE COUNT         2078 a          858 c         1134 g         1791 t
ORIGIN      
        1 atatgaatat tgtaacttgt gaataaggaa ttagcaggag aatactagtt cagcataaag
       61 gaagtgatgg gacttctgag acaactttct gttatgcaga aatacacata taaacagaca
      121 ataaacgctt ttccccgttt cttttaattt cctttacaat ttggttattc actaggtttt
      181 taaactttgc tatggtaaga tgatagaggc attattttat ggttaggagt gtatatatga
      241 ataaaaatgg ggagtggaat gcggcacgca gaatattcat tattcttatg gatgtacttg
      301 tattaaatgt atcgatctat cttagttttt tgctgaaatt ccagggagaa gtaccagtga
      361 gaaacttaga aacctttcag cattcagcaa tttttatttc catcatcttt attgcgttga
      421 atattttgtt aggagcttat gtattctata accgaatgat cagtgatatt gtcttcatta
      481 ctgttattgg acaagtacta atagcattgg ggatcatggt agttactttt gctggccgat
      541 ggtttgcatt tccgcgtggc gtcattttga tctcgtttat cctaggtacg atattactta
      601 gtgtttaccg gatagtcgtt tacaaactgt acttaagagt cagtcgtgat aagaaagtcc
      661 ttatcgtggg tttggagaaa gatgtcgcac cagctatcca aaattttcaa tctaagaaaa
      721 acaataaaca taaggttgaa gcagtggcaa tcgataatta ttacgaaaat acaaaaaaat
      781 tgatcgatga tatggatatc gtctatttgg cttctaaaat cccagaagat gaaaaaatca
      841 acatttatca attagtgact aaaaaagaga agaaattatt tttaaatacg acttttgaga
      901 atctgacaat gataaatccg aatattatga attttgaaga tgaaagcatc attgaagctt
      961 ctgggttcag aatccaacca gaatacgaac tattcaagcg tctctttgat atcatcgttt
     1021 cgcttatttt actgatcctc gcctcacctt ttatgctaat cacagcgatt ttggtaaaaa
     1081 caacttcacc tggaccaatc atctataaac aagtacgtat tacgaaaaat caaaaggaat
     1141 tttcaatcta taaattccgt tccatgagtg cgacagctga agcaaaatca ggaccagtct
     1201 tggctaaaag taacgatgca cgtgtgacac cagtaggtaa atttatccgt gctgtacgtt
     1261 ttgacgaatt acctcaaatc tttaatgtat tgaaaggcga tatgtcgatt gtcggtccaa
     1321 ggccagaaag accatttttc gttgatcagt tcaatgaaga aaatccttat tattacttaa
     1381 gacacaatgt acgtgcggga attaccggat atgcacaagt atacggaaaa tatgtatcag
     1441 attataacag taaactacgt tttgatttgt tgtatatcaa aaaatattca ttactattag
     1501 atttgaagat tttacttcaa acaatcaaaa tcttatttga taagatgtca tctcaaggac
     1561 tagatgaaga tgaaaatatt agttcattag cagaaatcga cttttcacaa gagaaaattt
     1621 atcgctagat tggaaaaatt ttgagcaaag aggtaggaga gaacattgga aaataaaaat
     1681 gtaagtatgc tgctttcttt atatgataaa gaaaagccag agtatttaaa ggaagcatta
     1741 actagtattt ttgagcaaac agtaatgcca aaagaaattg tattagttta tgacggccct
     1801 ataaatgaaa aacttcaagt agttgtcact tatttccaac aaaaagatcc tcacttgttt
     1861 acagttgtaa aattagaaaa aaatcaagga ttggggattg ctttagcaat tggattagaa
     1921 catacgaaaa atcgcttagt agccagaatg gatacagatg atataatgga accccaacga
     1981 ttagaaaaac aattagagat cttccaaaaa gatccagaaa tagcgattgt tgggagtaat
     2041 attgaggaat ttactggcac gcttagcaat gttatcggaa aaagaattgt acctgaatat
     2101 aacaatgcaa ttcgtgtatt ttctaaaaga agaaatccct ttaatcatat gaccgttatg
     2161 tttgataaaa aagctatttt ggaagtggga aattaccaac cattaagtgg gtttgaagat
     2221 tattatcttt gggcaagatt attaaaggca ggttataaag gatataatat tcaagaaaca
     2281 ttagtctatg cgcgaactgg caaagatatg tatgcaagaa gaggcggaat gaaatatctt
     2341 ggttctggtc ttatgggtcg ttatcgtatc tggaaagacg gtttagggtc agtaaaagat
     2401 tttataattg tttcttgcgg acatattttt attagcttac taccaaatca attaagagga
     2461 aaattttatc aaacgcaatt aagaaaatag gaggtttttc tttgtatagc actgatccaa
     2521 aaatgaaaaa aatacaacag attacgttga aaatgtctca agagattgtt gatttttgtc
     2581 taaaaaatca acttctttgt tatttctgcg gtggtggtgc catcggtact gtgagagaac
     2641 aagggtttat tccatgggat gatgatttag atttctttat gcctagagag gattatgaaa
     2701 aattttatca actatgggtt aattcagaaa aaagtaaaaa atatcccata cagaaggctt
     2761 ctaaaaatta taatgatcat aattctttta caactatccg cgatgcagat actacattta
     2821 ttaaaactta tcaaagagat ttagatatag tccatggaat tactattgat attttcccgt
     2881 tagatgttgc ccctgtttcg aaatttagcc gtaaaattca aaaactatgg gctttagtat
     2941 atgctttatt ttgttctcaa gtcgtccctg aaaaacatgg tggaataatg gctacaggta
     3001 gtaagatact cttatctatt ttccgctcac ctcgtacgag atataagata tggtcttttg
     3061 ctgaaaaaca aatgacaaaa tataataatg aaccaacggg ctatgtgact gaactttgtg
     3121 tcggacctaa atacatggga aatgtttatc ctgcaaaaga ctttgaatct gctgtgtggg
     3181 tgccattcga agatacagag atgccagtac cagttggtta tgataattat ttaagtcaag
     3241 tttttggtga ctatatgcag cttccgcctg aaaaagatca ggtttctcat catgaagcag
     3301 tttatattga tccagaacat ccatacacaa tgtacaaagg aaaatattat ttaactaaag
     3361 gagcagaaaa aaaatgatta cagctattat tattgctggt ggtgtgggta aacgaatggg
     3421 acaagatatc ccaaaacagt tcattacaat tgaaggaaaa cctattatta tctatacttt
     3481 agaatcattt caacaccatc ctcaagttga ccggatttta gtcgtttgca aatctggttg
     3541 ggaagaaacg atgtgggcgt atatcaaaga attcaatatt agcaaagtca aatgggtcat
     3601 tacaggtgga tcaaagggac aagagtcgat caataatggt gttcagtttt tgaaagacta
     3661 ttctgaagat gatgatacga tcatcatcca tgatggaatc cgtccactag tagacgaact
     3721 ggtattgtca gatgtaatcg ttaaatgtaa agaatttggt aacggtgtaa cctctctacc
     3781 ttacaacgaa caaattttta tcaagaaaac agaagaaacg acggaacagt atgtcgatcg
     3841 taacacattg aggcgtgtct caactccaca agcttatcaa tacggaaaac tacgggcagc
     3901 atatgaccgg gcagtgaaag aagacatcgg tatgactgat tcttcttata cgaataccat
     3961 gatggtagat ttgggagaaa ctttatattt tgctgctggt tctgataaaa atatcaaatt
     4021 gacaacaaca gatgatctag aattgttcaa agcatattta aaaatgaaag actaggtgaa
     4081 agatgatgac gttgattaaa caaccaatgt accaagaaga tttggcaaaa gtaatcaatc
     4141 atacaccaaa aataaaacag ctacatggaa aatccgttct gatgattggt gcttctggaa
     4201 tgatcggctc ttttttgatt gatacgttga tggctgctaa tgaacaacta ggcatcaaaa
     4261 tcaaagttta tgcaatgggc agaaaccgtc agaagcttga aaaaaggttt gccagttatc
     4321 ttgaattaga tactttcgaa attgttgaag gtgacgtcac agaaccctta ccaaaagaaa
     4381 ttcaagctga ctatttgata cacggtgcaa gtaacacaca tcctaaggct tacgcaactg
     4441 atccaatcgg tacgatcatg actaatcttg caggtacaga gcaagtattg aaacatgcag
     4501 tagcaaccca accggttaga gtattatttt tatcaacagt agaaatctat ggcgaaaatc
     4561 gaggcgatat agaaaaattc acagaagatt actgtggata catcgattgt aatacactga
     4621 gagcaggcta ccctgaagga aaaagagtca gtgaatcatt atgccaagcc tacatcgcaa
     4681 aacacgacct cgacatcgtg attccaaggc tttgccgtac gtttggtccg acgatgcttt
     4741 tatctgatac gaaagcatcc tcacaattta ttttaaatgc agtcgaacaa aaagatattg
     4801 ttttaaaaag tgaaggaaac caatattttt cgtatgtata tgttggagat gctgtttctg
     4861 ctattcttca tttactgctt gaaggagaaa aaggagaggc gtacaacgtt tcttcagaaa
     4921 actttgattt acgactaaaa gaattagccc aacagctagc tgatatcagc ggcaaacaag
     4981 taatttttga attgccggat gagattgaac aaaaaggttt ctcaaaagct agcacagcag
     5041 tacttgaaaa taaaaaaatt aaagagacag gttggaaacc aatttttcct ttgaacgaat
     5101 cattggttca tacagtagaa ttagttaaag gtgagaaata taatgtgtga gattagtatt
     5161 attgttcctg tgtataaagt tgaaaaatat ttaagaaaat gtgtagattc gattttagcc
     5221 caaacattta ctgattttga agttatatta gtagatgatg gatctcctga caatagcggg
     5281 aaaatctgtg atgagtatgc tgaaaaagat aatcgagtac gtgtgatcca taaagaaaac
     5341 ggcggattaa gcagtgctag aaatgcgggg attgatgttg cgagaggcaa atacttaggc
     5401 tttgttgaca gtgatgatta tattgatgaa gatatgtatg aaattttgta tgagaatttg
     5461 aaaattcatg atgccgacat tagctctgtt gaattgattc ctttttatgg tgatagatat
     5521 aagaaagcta ataaagaaaa gaaagtaatt atattaaata aaaaggaagc aataaaatct
     5581 gttttagaag gaacgcaatt ttatgcatac gcatggaata aactttatcg taaggaactt
     5641 tttaaagata atcgttactt ggatggaaaa acatttgagg atgcatatat aataatagat
     5701 ctattatttc aaacagaaaa aattgttgtt tccaatgaag agaaatattt ctatcttcaa
     5761 agaaatgata gtattatggg aaaaagtttt tctatgaata atttcgatgt tatagaagca
     5821 tggcaatata acaaagagaa gattttagat gcttttccag a
//
LOCUS       DADQCX010000126         5816 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.130, whole genome shotgun sequence.
ACCESSION   DADQCX010000126 DADQCX010000000
VERSION     DADQCX010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.130"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            213..1109
                     /locus_tag="J8R83_002539"
     CDS             213..1109
                     /locus_tag="J8R83_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAZ9575648.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1259..2200)
                     /locus_tag="J8R83_002540"
     CDS             complement(1259..2200)
                     /locus_tag="J8R83_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAZ9575649.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2326..3447
                     /locus_tag="J8R83_002541"
     CDS             2326..3447
                     /locus_tag="J8R83_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAZ9575650.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3705..5207
                     /locus_tag="J8R83_002542"
     CDS             3705..5207
                     /locus_tag="J8R83_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAZ9575651.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5274..5801
                     /locus_tag="J8R83_002543"
     CDS             5274..5801
                     /locus_tag="J8R83_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9575652.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         1914 a         1027 c         1219 g         1656 t
ORIGIN      
        1 atatttaaca atgactaatg ataacaaatt ttcagacaat tacaactatt cagaaaactt
       61 ttaggcgaat tttaatagaa gaatgattta tttcatcata ttttcataca aatgttaaat
      121 tttcatacaa atataggaaa cgttttactg gctttttact atttaaacag gctatcatag
      181 gaaaaagtga cagagaaagt gaggcggaaa agatgaacaa aaatgacgta ctgctagttg
      241 caaaaaataa atcactttat tttttgcctt ccatccgctc tttagatgtt tggtccggaa
      301 aagatttact acagtcggaa ttcattaaat cagctagaca acagttggca aattatcagc
      361 tgatcgtttt tttagattat ggatttgata tggagatggc tcgacgcgtg cgcccattta
      421 ccaatgcaaa aattgtgtta tttttttgga atcacttcaa agcagaacac gaggcgatgc
      481 tgaagcaggc acaagatgaa ccggcaatcg atgagattta tcattttgat tttttggaag
      541 caaaagaact tgggctgaaa cataatagtt cattttattc gaaacatatg aatttttctt
      601 ctagcgaacc aaagacggat ctattttttg gtgcaacgaa taatgggaga aaagaacgag
      661 cagaaagcta taagcaggaa tttataaaaa gagatgttac gaccaactat ttcattcttc
      721 cacatcgagg gaatgaacaa cctggatatc ttacttatga agagtacctg aaaaaaacag
      781 gggaatcgcg cgggattctg gaactgttgc gggagggtca gcaaggagtg actttgcgga
      841 catttgaatc catgtatttt caaaagaaac tagtgacgga taatcaagcg attgctcatt
      901 atcattttta tcgtcctgaa aatatttttt tgcttcgaga acgtgattta gatgaattac
      961 cggaatttct gcatacacca tttaagccaa tcctatcaga gctattggaa ttttatgatg
     1021 cagaaaattg ggcaaaacga tttatcacta acgattccac tatttatgag caatacgaat
     1081 atgacctctc ctctgttgaa aacaaataaa aaacctacat tttgaagaga ttatgtactg
     1141 aaacaaacaa gcacaattct tatggcatca tgagagttgt gttttctttt tgatctttta
     1201 ttgggcttaa aaaaagagaa ccagctgctg attcagctga ttctcatcag agagcctttt
     1261 attctgcgcc aaggattcct tcttttgcat ggactaattg ggtcaaaaag gcacaatatg
     1321 gtgtagcaat atcatatttt tgtccttttc gccaaatggc accattgatg tagtcgattt
     1381 cagtcaaacg atggtttttg atcaggtctt ggtacataga tgggtaatgc aacccgatgt
     1441 tgtcaggatc ataagtagaa gcaatatgtt ggtacacttc ttcttgatct agtatgattc
     1501 cttcttttgc tgcgatagaa gcaaattcag atacgattgt tcgaaccatg ctctctgccg
     1561 ctttttgcgc gcctagttca gcaatattac aatccaaaat cgtgcataaa ccattcaatg
     1621 ttccatttac acaagctttt cgccaaatgg aataacgaac gttatggcta tagatcggat
     1681 ttaaatttgc ttcttgaaag acttctacaa ctttttttgt aaatgcttcg ccttctggtt
     1741 ccaagttctc tagttcgatt tctccatcac ctaacaatgt gacttttccg ggaccagcta
     1801 gaccagctgt ccacatcgtg atcccaaata agatattttt ctttggcaca tatttttcca
     1861 gtacatcttc atgacctaat ccatttagta aacacaaaac ataagtattg tcagtaataa
     1921 tggattggat cgaacaaaac atatcatcta attgattggc ttttgttaat gctacgatca
     1981 agtccacgtg ttcgttgctt tcgatgattt cttctggtga atagattggc agttttgcga
     2041 ccacttcttt accgttaaag tcagcaatca acccatttgt acgaatggct tcaatgtgag
     2101 caggccaacg atcgatcaag aggacctcat ttccgctttg atgtagcatc aatccgattc
     2161 ggctgcccat tgctccggcc ccagctattg cgattttcat gttttttctc tcctttattc
     2221 aatgagttcc cttttagtat atagaaaaat ggaagaaaat agcattgttt tgtttgaaaa
     2281 aaatgaaaaa aagtgtctta cttaagaaga aagtgaggga tacagatgga tattttggcg
     2341 gcaattgatt catttaaagg aagtgcttct tcatttgaac taaatcaggc agttctaaat
     2401 ggctgggaag atcgtaaagg aagaaaaatc aatgtgccga ttgcagatgg cggagaaaat
     2461 actgcagaag caatctatta cgcgctcagg ggaacatggc gtaccattga tgggatggat
     2521 ctcttattcc gtcagcgaaa aatcagctat ttattgacaa cttggcaagg aaaaaacacc
     2581 gcagtcatcg aatctgcaca agcattgggg ttagatctac ttgataaacc aacggatcaa
     2641 actatccgac ttgcttccag ttatgcctta ggagaactta ttaaagatgc actgcttcaa
     2701 gaagtagaac aaattattgt cactttagga ggaagcgggt gtagcgatgg tggtctagga
     2761 ttactccaat ccttgggtgc ttctttagaa gggtacacag aaggaaatcc tttattatct
     2821 actaaaaaac ttcattttga tcgaagaaac gttcttgttt ctaaagtaaa attgattatc
     2881 gctgcagatg ttaccaatcc atatacaggt caacaaggag ctgcttggca atttggaaga
     2941 caaaaaggag gaatagatac gacgctagct ttcttagata aacaagcagg aaagattgct
     3001 cagcaaataa aagatttctg ggaggtggat ttagatgata ttccaggaag tggagcagca
     3061 ggcggtattg gtggagccct ttttttgttg ggagcgaaga tggtttctgg tttcgattta
     3121 gtcagccaaa tcactggatt ggaaaaaaag atcgaacaag cagatgtcat cattacagga
     3181 gaagggcgga tcgatcagca aacgatccac ggaaaagttc catacggtgt agcagtgctt
     3241 gcaaaaaaat atcgaaaacc aataatcgct atttgcggaa gtagagacca agagctagaa
     3301 ggactttctg attttctccc aattgtctta agtattcatt tgggtccaat aggtttagaa
     3361 gaagcaatgg aacacaggca aacattagaa aaaacaaaaa tcttaggaca gacacttagc
     3421 agatttttca ccatcctccc gaagtagttg acaaaatcat tttctttatg ctatcgtaat
     3481 ttcaaatata ggacaaagtg agggatccgt gcattgaaaa attaagtcga ttgatgaaag
     3541 ctgcattcag actgtacctt gtggagacaa ggaagcagtg tgcagatttt cgggattggc
     3601 ttggtttttt cgatgtatgg gtctttttgt gtgtatccaa cccttgcatc ctctttagcc
     3661 agttctgaaa ataggactgg tcttttttta cgaggtgatg gaaaatgtct aaaatcgaaa
     3721 taaaaaatct gacattcggc tacgacagcc aaggcacatt attatttgaa caagcaaatc
     3781 taaattttga cacacaatgg aaactaggac ttatcggacg aaacggtcga ggaaagacaa
     3841 ctttactgaa tattctacaa aacaaactac cttatcaagg gcaagtaatc catcagcaag
     3901 aatttgccta tttcccgcaa cagacaaaag ataaagaacg tttaacctat tacgtgttaa
     3961 atgatattac ggattttgag atatgggaaa tcgaaagaga gctccaattg atgcaaacag
     4021 atcctgaaat cttatggaga gaattcagca cactatcggg gggagagaag acaaaagtcc
     4081 tactggcact tttatttgtg gatgacactc atttcccgtt aatcgatgaa ccaacgaatc
     4141 atttggatat ctctggtaga aaacaagtag cggcttattt gaaaaagaaa aaacaaggct
     4201 tcatcgtggt cagccatgac cggggattta tcgatgaagt agtggaccat gttttagcaa
     4261 tcgaaaaaag tcaactggaa ctttatcaag ggaatttctc tatctatgaa gaacagaaaa
     4321 aacttcgtga tgaatttgaa atggctcaaa atgaaaaatt gaaaaaagaa gtcagtaggc
     4381 taaagaaaac agcagctgaa aaagccgaat ggtctcgttc ccgagaagga gataaaacaa
     4441 agaaacaagt cggattcatc gatactgaat ctagacgagt gaataaagga gcagtgggtg
     4501 ctgatgctgc acggacgatg aaacgatcca aagcaatcgt gaatcggatg gagacccaga
     4561 tcagcgagaa agaaaaacta ttaaaagata tcgaatatat cgattctttg acgatgaata
     4621 gccaagcgtc tcaccataag cgacttttaa gcgtagaaga tcttcaatta gggtatgaaa
     4681 atctgttatt cgagccaatt cattttacaa tcgagcctca tcagcgggtg gcgatttcag
     4741 gtcctaacgg tgcaggaaag tcatccatta tccattatct tctgggggca ttcaacggca
     4801 aggttatagg agaaaaatac cagccaaaac atctgagcat tagttatgca agccaaaatt
     4861 atgaagacaa tcgaggaacg ttggcggaat ttgcagagaa aaaccaagta gactaccaag
     4921 catttttgaa caacctccga aagcttggga tggaaagaga tgtttttcat aacaagatcg
     4981 agcagatgag tatgggccaa cggaaaaaag tggaattggc taaatcttta tcacagccag
     5041 ctgaactata tacatgggat gaaccattga attatttgga tgtcttcaat caagaacaat
     5101 tagaacaact gatcttgaac gtgaaacctg ccatgttact agtggaacat gatcaaacct
     5161 tcctggataa agtatctact gagattattt ctcttgagag aatctaaccc ttgtaatctc
     5221 aagaacaaca aggtatggtt aaggggaact ttgccaacga aggagagaat cacatgcttt
     5281 atgtaacgag acacggagaa acaacttgga acgcacaagg attagtttgc ggacgggcag
     5341 atgtgccgct gactgaaaaa ggacagatgc aggcacagaa actagcagaa aaggtagtag
     5401 atttgcctgt tccaatcacg aaaatcatcc attcccctct tcaacgagca agagatacag
     5461 cacaagcagt tgctgatcgt ctcagcttgc cgctgaccgt tgatgaacga ttggtagaaa
     5521 tggattttgg ggattatgat ggactgccaa gcaaagatga gaactttcaa aaagcacgtt
     5581 tagcgttcgc tgtacgattc ccaaatgggg agtcagtctt agatgtgtat gcacggatcg
     5641 ttcctttatt gaaagaatgc atcgaagacg aagaaaatgt ctatctgtta gtttgccata
     5701 atgccttgat aagagtgatc aatgcttatt ttcatccgat gcctaatgag gggttcttta
     5761 cattcatggt agataataca gaattggttt cttatgagta attatgtttt tgtgtt
//
LOCUS       DADQCX010000127         5806 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.131, whole genome shotgun sequence.
ACCESSION   DADQCX010000127 DADQCX010000000
VERSION     DADQCX010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.131"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(79..1518)
                     /locus_tag="J8R83_002544"
     CDS             complement(79..1518)
                     /locus_tag="J8R83_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HAZ9575653.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1519..1911)
                     /locus_tag="J8R83_002545"
     CDS             complement(1519..1911)
                     /locus_tag="J8R83_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575654.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            complement(1968..3140)
                     /locus_tag="J8R83_002546"
     CDS             complement(1968..3140)
                     /locus_tag="J8R83_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAZ9575655.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(3247..4737)
                     /locus_tag="J8R83_002547"
     CDS             complement(3247..4737)
                     /locus_tag="J8R83_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAZ9575656.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KKSMIGGRGVVLTSEEAIHENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTLIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKLVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREALGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALSEFFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(5132..5371)
                     /locus_tag="J8R83_002548"
     CDS             complement(5132..5371)
                     /locus_tag="J8R83_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575657.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSLIESGKSDPTL
                     KTLERIAELTNSTLVIDLIPNELEQVELQIEEEKQ"
BASE COUNT         1758 a         1033 c          774 g         2241 t
ORIGIN      
        1 acttccttta ttatttttca tttttttaaa ctatttaata ctaatgtctt ttataatagc
       61 ttttcatata ttatataatc aatctttata agtcctttta taaatttctt ttctaccatt
      121 ttcgataaat tcctgtttaa tatttttaat tccataaaca atagtttcaa taggataata
      181 ttcttcaact atatcttgat attcttttgc tttctcaata tctatatttc catacattct
      241 taatatatct tctccaaaat ttgttcctat ttcttcttca ctatcttcaa gtaagtatat
      301 aaaatcacaa tattcatcta taattccaga atctccaaaa tcaattattc cagttaatct
      361 attattgcca tctaacaata gatgattaca actaaaatca ttatggcata aacacttttt
      421 accctcaaaa actgttgttg catttagtct ttccataaaa ctttctatat aatctttttc
      481 tatatcagtt aaatcattat aaatagtttc acgcaacaat atatactctt ctaatacatt
      541 ttgtttatta tcaatagtac attcactaat atctgtataa tctaaaccgt gcatttgtct
      601 taaaaaactg gcaatatctc gttttaacaa attttgttct tcttctgaca tagtagaata
      661 aatttctggt gttaaaaaag ttcctttaat ttctttataa cctagtatag ataattcatc
      721 actaatatac gaatattcaa tattaggaat ttttacatta gtttctaaat ttgtatttaa
      781 aaaattatat attgcttttt cttttgcata accttttttc ttattagtac taaattttgt
      841 tttaaaaatg tattcattat taactaaata tgccacacta tcataaccac taccgattat
      901 ttcaatacta tctactttga aattatcaaa gtaatgctca attaaatatt tcattgcctt
      961 aacatttgtg gcattatcat catatctata ttccattaaa taacaatctt cttttttgcc
     1021 ctcgtgtaat tcatgttctg gcaaatcttc aataattcta aaaccagatt tttggtatgc
     1081 ccttattgct cttggattat ttttatgagg gtctaaaata actgcattag catttctttc
     1141 ttttttcaaa aattcaaaaa tcaatttaat atatcttgta ccaattcctt tactccaata
     1201 atttggctct cctataaatt gatccatacc atagactatc tcatcagttt ttggataatg
     1261 ataatcagta tataactcat catacatttt atatatttgt ccatatccaa taggaacatt
     1321 gttatattca ataattactc taaaaacttc atcttcccaa ggctctgtat aatgtttttt
     1381 taatgattct aatgtatatt ttttatctct accatcataa aattctaata ctctttcatc
     1441 agttaaccat tttaacatca aaggaaaatc atcatctatt aaagttctta tacatatttc
     1501 attttcaact atattcattt atttatcacc tttttcataa tcatatacat atactatttc
     1561 atctttataa tcatttttac cacctaattt ttcatataca tggcaagctc taggattacc
     1621 tttatcagtt attaaaaaca tttcagaaca accaatctct ttagaatatt ccttaataaa
     1681 agataataat tttgaaccat aacctttgtc ttgatagtta ggtaacattc ctattgagtg
     1741 taaataaaac attgtttttc catcaggtct taaaagtgta tagcaatatg caaatcctat
     1801 aattttatta ttttctttag ctataaaccc aaatgaactg gtatcattaa gaaatccttt
     1861 taaattatca atatcaaaaa ccatattatc atcaattaaa acttcttcca taaactcagt
     1921 caagtccaga ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa
     1981 ttgatgtatt ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca
     2041 attaagcgat tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt
     2101 acttcttgat tcagtcgttc aattagattg gtactcttta gtcgattgtg ggaatttcct
     2161 tgtacggtat attgaaaggc gtcttcgaat ccatcatcca atgatgcgca agcttttgaa
     2221 tattttggtt gatcgatata atcatgaatc aatcgatttt tagcctcacg cgctaagtta
     2281 atatctgtga acttaaaaat tcctttaaca gcttctctga aagattttga atttttttta
     2341 ggaatggtgg taaagatatt tcttaggaag tgaacttggc atctttgcca acttacgttg
     2401 gtgaaggatt ttctaatggc agagactaat cctttgtgcg catcagaaat aacgagttcc
     2461 gtaccttgta aaccgcgttc ttttaggtat tcaaaaaatg ttgtccaggt ctcttcgctt
     2521 tcgccacttt gaatcatgaa gccgataatt tcacggtcgc catctttggt tattccaatc
     2581 gctatatgac agctttttga gagtactcga ttttcttctc gtacttttat atagagtaca
     2641 tcggtcatta agtaaggata atttttttct gataataaac gattctgcca ctcgttaacc
     2701 ataggttcta gctgttctgt taagctagaa acgaaggact tagagacgga tttaccacaa
     2761 agttcttcca caatttttga tactttacga gttgaaacgc ctgatacata catttccaac
     2821 attgaagcca tgagggcttt ttcgtttcgt tgataacgtt caaacactgt gggtgaaaaa
     2881 tggccatcac gtgttctggg tacttttaat tctagcgtgc ctacacgtgt cgtaaagctg
     2941 cgctcataat agccatttcg ttgactttgt cggttttctg ttcgttcata ttcttttgct
     3001 tgaatatatt ctgttcgttg attttccatt agttgattaa ataccgttgt taaaatattt
     3061 ttagaaacgt catcctttac agaatattca ataatgcttt gaatctcttc gcttttcagt
     3121 gtaaaatgta cttgggtcat gtaaaagtcc tcctgggtat gtttttgtcg ttaaaaacat
     3181 tgtaccgtaa aaggactgtt atatggcctt tttactttta cacaattata cggactttat
     3241 ctattttcag cctgtatcat agctaaacaa atcgagttgt gtgtccgttt ttgggcgttc
     3301 tgctagcttg tttaaagtct cttgaatgaa tgtatgttct aagtcaaaaa actctgacag
     3361 cgcctttata tagctttctt tttcttcttt ttttacttta atgatcgata gcaacaatga
     3421 tttaacacta gcaagttgaa tgccaccatt tcttcctggt ttaatcttaa agaaaatttc
     3481 ctgattcgcc ttcagtacct tcagcaattt atctaatgtc cgctcaggaa tgcctagcgc
     3541 ttctctaatc tcttttttag tcgtcaccaa ataaggcttg tatacatcac ttttttcgct
     3601 aatataagcc attaaatctt ctttccattc tgacaaatga acacgttgac gttcacttct
     3661 ttttttcttg aatttaaacc acccttgacg gacaaataaa tctttactgg ttaaatcact
     3721 tgatacccaa gctttgcaaa gaatggtaat gtattcccta ttagcccctt gatagttttc
     3781 tgaataggca cttctaacaa gtttaatcac ttctttttct tctaagggtt gatctaatcg
     3841 attattaaac tcaaacatat tatattcgca cgtttcgatt gaatagcctg aactaaagta
     3901 ggctaaagag agggtaaaca tgacgttatt acgccctatt aaaccctttt ctcctgaaaa
     3961 tttcgtttcg tgcaataaga gattaaacca gggttcatct acttgttttt tgccttctgt
     4021 accgcttaaa accgttagac ttgaacgagt aaagccctta ttatctgttt gtttgaaaga
     4081 ccaatcttgc cattctttga aagaataacg gtaattggga tcaaaaaatt ctacattgtc
     4141 cgttcttggt atacgagcaa tcccaaaatg attgcacgtt agatcaactg gcaaagactt
     4201 tccaaaatat tctcggatat tttgcgagat tattttggct gctttgacag atttaaattc
     4261 tgattttgaa gtcacataaa ctggcgtttc taaaacaaaa tatgcttgat aacctttatc
     4321 agatttgata attaacgtag gcataaaacc taaatcaata gctgttgtta aaatatcgct
     4381 tgctgaaata gtttcttttg ccgtgtgaat atcaaaatca ataaagaagg tattgatttg
     4441 tcttaaattg ttttcagaat gtcctttcgt gtatgaacgg ttttcgtctg catacgtacc
     4501 ataacgataa acgtttggtg tccaatgcgt aaatgtatct tgattttcgt gaatcgcttc
     4561 ttcggaagtc agaacaacgc cacgtccgcc aatcatgctt ttttttgagc gatacgcaaa
     4621 aatagcccct ttgcttttac ctggcttggt agtgattgag cgaattttac tatttttaaa
     4681 tttgtacttt aacaagccgt catgaagcac agtttctaca acaaaaggga tattcattca
     4741 gctgttctcc tttcttacga aaattaatta gttagaagct acgatcaaag ttgaatcaca
     4801 acaaaaaagg caatcaacta agtttttctt aattgattgc ctggtatctt cttaaagact
     4861 tgaaattccc tcaaaaaccc gatataatgg gtttacagat atttaagtat ctgattaata
     4921 aagtaattaa atactttacc aaatttcggg tctcgacttc tttaattgat tggtggtaat
     4981 caattaaggc tcgcaactta ttttcttggc ggaaaataag ttggtcgtgg ctcttttttt
     5041 gtattcttta ttcagttcgt tgtttcgtta tatctagtat accgctttta aaaaaaataa
     5101 gcaacaattt cgttaaatat attaacgaca atcattgctt ctcttcttct atttgcaact
     5161 ctacttgttc taattcatta ggaattaagt caataactaa ggttgagttt gtcaattctg
     5221 caattcgttc caatgttttt aatgtcggat ctgattttcc tgattcaatc aatgaataat
     5281 ttgatctact catttctaat tcttgggaga atttttcttt tgatttggta cctctcatct
     5341 tttttaagct ttctctaaat gctagttcca agtttctccc tcctgtttat gtaagtattt
     5401 tgcacgtttt ccatttaatt atatcgttac accttgtaaa tcacaagtga ttaatcacaa
     5461 atcacttgtg attagtgatt gttattggtg ttgcctagaa cgattctaag cacatgttta
     5521 attttaaagt gggcaattat ctttaaaatg tcctacaatg attcaataaa agcatggctg
     5581 ctagtgaaac ttgcgaccat gcttttaaaa atacttaatg gggtcccgag cgctttagct
     5641 ccttggaagc tgtcagtagt atacctaata atttatctac attcccttta gtaacgtgta
     5701 actttccaaa tttacaaaag cgactcatag aattatttcc tcccgttaaa taatagataa
     5761 ctattaaaaa tagacaatac ttgctcataa gtaacggtac ttaaat
//
LOCUS       DADQCX010000128         5755 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.132, whole genome shotgun sequence.
ACCESSION   DADQCX010000128 DADQCX010000000
VERSION     DADQCX010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.132"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..731)
                     /locus_tag="J8R83_002549"
     CDS             complement(<1..731)
                     /locus_tag="J8R83_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9575658.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADK"
     gene            complement(1095..3761)
                     /locus_tag="J8R83_002550"
     CDS             complement(1095..3761)
                     /locus_tag="J8R83_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9575659.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            4102..5553
                     /gene="cls"
                     /locus_tag="J8R83_002551"
     CDS             4102..5553
                     /gene="cls"
                     /locus_tag="J8R83_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAZ9575660.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
BASE COUNT         1658 a         1219 c         1009 g         1869 t
ORIGIN      
        1 tttttatctg cggaccaaag gagcagtcta taggtcagct tagtcgtact aaggatttct
       61 cgtttttcac tgaatagttt gcgaatgtac ctggtcacaa caggatcttt tgcgtacgcg
      121 tcatagtata gcttcatcaa ttcttcagta attgattcct gtgtaaaata agtaaaatct
      181 tttttcttca ctttgaatcc ttcatcaatt aagtatgttt caaattgatc cattacaact
      241 ggcgatgtat taggatcttc ttctatcatt cctagttgct tttcgatagg ataaaaaaca
      301 tcatcgattg attccactac tctgattatc acgcaccatt tgcttgactt tttcatcaat
      361 ttttctaatt gaataagatg taccaatgct ggatttgctg ctgtaaaaac catttcatat
      421 gtctcatttg attggataaa ttcttctaac gactgtttga taaaggaaac atttggcaac
      481 tcattttttt ctgcttcttt ttttgcattt tctagcattc ctgaagaaaa atcgatcaaa
      541 tcatagcgat taatttcttt tgctaaggaa agaaatctgc cagatcctcc agcaacgtct
      601 gctgctgttt cagcaggcag gactttctcc gttttcagat aattttttac atcttcagca
      661 atagttactt gcgattcttg ctggatttca taatattctt cagcaaattc atcccattct
      721 ttttcattca tttgatttcc tctaattttt tgttatatgt tttcactttt cggaataaat
      781 cattctcctc ttttatctat tctatctctt ttgatgaata ataaaatgat tggctttccg
      841 tctatcataa ataaaaaaag ggactgtgac caaagtcgtg tcaaagtccc tctttccgaa
      901 taaacagtgt ccaatcagat gaccctcagt attagctcaa aatgctgatt ttacaacttc
      961 ttccttaaac ggtgttctcc tgccaactct tcggtcacaa gtcacaatat tcaacaaaca
     1021 tgagaagctg tttgttgaaa ttgcaccttg tgactcagaa ttaaacggca ggctcacaac
     1081 ctcgttgatt cgttttattt atttccttgt actcgtacaa tgatcaattt agtgatttcc
     1141 atcaaaacaa ttgtcacaag tgcgattccc atacatgtaa agacttctgt caatccaaat
     1201 gctgatggga tagagaagac ttctttcagt cctgggatca ttgttaagca gtaaagcgcg
     1261 ctacatacaa ctacagctag taagacactt ctgttagaga agaaccctgc ttggatagct
     1321 gtttgtgtgt ttgaacgtgc tgggaatgtt tgcaatgtcc gacaccaaat caatgttgaa
     1381 aatgacatgg ctacaccgaa ttcaggtgaa tgctgcatgc caagccattg agcaaagata
     1441 acagcaatcc caatcagcac accacgatac gttacagaaa tcaatgtttt gtccgtaaag
     1501 attcctgaat ttggatctct tggcgggcgg ttcatcgtag caggttcagc tttttctgta
     1561 cctaatgcaa ttgctggcag tgaatcattg actaaattga tgaacaacag ttgtaatgct
     1621 gtaaatggat tggaccagtc agcaactaag gcaaagatga tcgcaatgat cgcacctaaa
     1681 tttcctgcaa atagataaga aatagctttc ttgatattat caaacacatt acgtcctact
     1741 tctactgcgc tgacaataga agcaaagtta tcatccgtca ataccatcgc tgctgcatct
     1801 tttgccacat ctgtacccgt tcccatagca attccgatgt ctgcttgttt caatgctggt
     1861 gcgtcattta caccatcacc tgtcatagct gagatatgac ctttattttg ccaagcacga
     1921 acgatacgaa ttttattctc aggtgaaaca cgtgcataaa cagtgacttt ttctaaaact
     1981 tcgtttagtt gatcttctgt caattcatct agttccgtcc cggtcaaagc caggtttcct
     2041 tcttcaaaaa tcccgatttg ttttgcgata gcaacagctg ttgttttgtg gtcaccagta
     2101 atcatgattg ttttgattcc tgcacttctt gcttctgtta ccgcctgagt cacttcagca
     2161 cgtggaggat cgatcatagc aagcaaacca acaaggatca aatcgtcttc atcttcaaat
     2221 gataaatcaa aattatcaag tggacggtaa gcaaaagcta gtacacgtaa tgcgcgtgtt
     2281 gaaaaagctt cattttgctc ttggaatttt ttcatcaatt catccgtcat cggaacgact
     2341 tcaccattta gcaatacttt tttactgcgt tggaagacga tatctggtcc gcctttaaca
     2401 aacaagtaat ttttgttatc aattgtgtgt ccagtagaca ttaattttcg atctgagtca
     2461 aaaggaagtt ctgcttgtct tgggtagttg tttcggattt cctgataagg ctggtttaat
     2521 ttttcactaa agtcgataaa cgctacttcc gtagggtcgc ccaatttagt accgtcttca
     2581 ctgatcgatg catcattcgc taaaacactg atttcgatca agcgacgttc gtcagctgtc
     2641 cattttgaag ggtcatttgt gaaatcccca gtatcgccat tacctaaaaa gtagtcaaca
     2701 actgtcattt tgttttgtgt caatgtacca gtcttatctg tacagatgat acttgtcgaa
     2761 ccaagtgttt caactgctgg aagcttccga ataatggcat gacgttttgc cattttattc
     2821 gttcccaaag ataacacgat tgttacgata gactgtaatg cttctggaat agcagctacg
     2881 gctacggcta cggcaaacat cactgcgctg acgatatctg cagtcatatc tcctgtacct
     2941 tctccaagat aaatacgaaa cagttggata cctaaaatca ataaagacaa tgccaaaata
     3001 gccaaactta gttttttact gaatttatcc agacctcgtt gtaacggagt gacttgctca
     3061 gttgttgatt ccaaaaggcc agcaacttgt ccgatctccg tattattccc agttgaagtc
     3121 actaagaatt taccgcgtcc gtaagttacg atcgttccac tgaataccat atttgtacga
     3181 tctccgattg gtaccgtact tgtgatatcc gttacttctt tttctgcaga agtcgactct
     3241 cctgtcagca taccttcatc tacttttaat gatcccgcat ctagtaaacg tccatcagca
     3301 ggtacataat cgcctgcgtc taacaacacg atatctccta ccacaagttc gtttgccgga
     3361 atcgtttttt ccttaccatc acgaatcact cgagcatcgg gcgctgaaag gtttttcaac
     3421 gcttctaaag aaccttctgc tttttttgtt tggacaacac tgattataga attcaacatc
     3481 aatactgcaa aaataactaa gaattcgatg tagtcaccca tgaccatctg aatcagtgcg
     3541 acaatcagca atacgataac cattgcatct ttgaaagttt ctaagaacaa tttccaagtt
     3601 ggcttcttcg gcttttcttt tagctggttc aagccatctc tttctaattt ttccttcgct
     3661 tgcgtggtgc tcaatccatc ggttgagctc tgcgtttgct gcatcaacga gtcgatcgtt
     3721 tctttataga ccgcttgttg tgcttgttcc ttgttttcca aatttcatcc cccatttttt
     3781 gatcttggcc ctagtcctgt ctgaaaaaaa agagacctaa gacaaatacg catttgtctt
     3841 aggtctcacc atttcataca ataccagaaa accatttggt taacttactg ttgatattat
     3901 cgcaacaaac gttgccggtt actcccctaa ggagatattc aactgtacta atatcctacc
     3961 ttattaacct acaaaaagca actactttag cccgatttac ctacattttc atgaaaggag
     4021 tgaaaagtat attcaccttg gtaggcttct ttcttctatc atgctatact aatgttattg
     4081 tatgtaagga ggaacatttt tgtggtatct agtattataa ccgcccttta tctattaaat
     4141 gcacttattg ctttggtggc tattttgatc aaaccccgag atgtagcagc catttgggca
     4201 tggctcttag tattgtttgc ccttcctggg gtgggctttg tattatattt atttttcgga
     4261 cgtggattaa cggataagaa aaaattctat ctccgacaaa gtgacttgaa agaattagaa
     4321 aactttcagt cttttagagg agataccatt gaacattacg atcctgacat gggcgataaa
     4381 gacaaacagc aatttgttga cttcttctct tcattaaatc gtatgccgct gacaagaatg
     4441 aattctgtca ctcttctcac agacggacaa gagaaattgg attcactgct tcaagatcta
     4501 aaaaaagcca aacattcgat ccatatcgaa tattacgcat ttgtgacaga taatatcggc
     4561 cagcaagtct tacatgtttt agaagaaaaa gccgcagaag gcgtggaagt tcgaatatta
     4621 tatgatgcat ttggctctca tggcacaaaa gcaaaagatt tcaatcgtct aatcaaaaat
     4681 ggtggacatg tccatacatt tgttacctca caaagggcat tacttcgttt ccgattgaat
     4741 taccatgatc accgaaaaat cgttgtgatc gatggaaaga ttagttatac cggtggtttc
     4801 aatattgcca atcaatatgt aaatacaaca aaaaaattcg gctattggcg cgatacgcat
     4861 atacggattt tcggtgccgc ttcttctttg ctccagcttc gcttcttaac agactggaac
     4921 gtctcggtac ctgaagaaaa aaaggtcggc tatcatttga attatttctt taaaaaagca
     4981 gatcgagatg aatctaagct tgctgataca tccatccagc ttgtttcaag cggaccgaat
     5041 aacgaaaggg aacaaatcaa gctttcattt atcaaattga ttacttctgc taaaaaacgt
     5101 gtttggatac agacacctta ccttgttcct gatgaaagtg tcattgctgc tttaaaaatc
     5161 gcaactgcct ctggtgtaga tgtgaaaatc atgattccca acaaaccgga tcatcctttt
     5221 atttatcgag caacacaata ttatgctcgg cagctgatca aggaaaatgt acaaatcctt
     5281 gtctatgaga acggcttcct ccatgcaaaa acattgataa tggatgatga aatctgcatg
     5341 gtaggttcag caaatcaaga tattcgtagc taccgattga attttgaaac aagtgctgtc
     5401 atttacgatc ctgagttttt agaagaactt gctactcagt tcaaagaaga tgagacacat
     5461 tgttcatcca tgacaactga aacagtcaag gaaatgtcta actggctatt attcaagcaa
     5521 caaatttctc gattattttc tccaatccta taattttttt attcaagtag agaaaaatat
     5581 actaagatta aagggactgt gacaaaaatc ttgtcacagt cccttcttcc gaacaaacgg
     5641 tgttctcctg ccaactcctc ggtcacaagt cacaatattc aacaaacatg agaagctgtt
     5701 ttttgaactt gttccttgtg actcggagct ggacggcagg ctcacgacct ctttc
//
LOCUS       DADQCX010000129         5744 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.133, whole genome shotgun sequence.
ACCESSION   DADQCX010000129 DADQCX010000000
VERSION     DADQCX010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.133"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            872..1840
                     /locus_tag="J8R83_002552"
     CDS             872..1840
                     /locus_tag="J8R83_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9575661.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            1857..2381
                     /locus_tag="J8R83_002553"
     CDS             1857..2381
                     /locus_tag="J8R83_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAZ9575662.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            2757..3038
                     /locus_tag="J8R83_002554"
     CDS             2757..3038
                     /locus_tag="J8R83_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575663.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            3040..3456
                     /locus_tag="J8R83_002555"
     CDS             3040..3456
                     /locus_tag="J8R83_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575664.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            4086..5240
                     /locus_tag="J8R83_002556"
     CDS             4086..5240
                     /locus_tag="J8R83_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAZ9575665.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            5234..5656
                     /locus_tag="J8R83_002557"
     CDS             5234..5656
                     /locus_tag="J8R83_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575666.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
BASE COUNT         2204 a          985 c          905 g         1650 t
ORIGIN      
        1 ttatgagcga actaatgcaa aatttggcta gcaaaaaaag ttaaaaaata tatgctaata
       61 atcgagcgaa atgaacactt tttcaagtga gcgaatccgc catgacaaag ctgaagcagt
      121 ttatttcagc tttgtcatgg cgtgtgccta gacttttaaa aaagtcggca cacgagcaaa
      181 tatctttatc aagctctaat ttgcgtttta agacgtttga aacgtctaag tatataaata
      241 tataagagta ggtttaagag tgcttaaatc gaattttaga gggcattcag acaactttag
      301 ggttgttagg gcttgccctg accgcctgta aggcgcttta agaacaagat aagggattta
      361 tactaagact gtcttaaaac gtctcaaacg aaggctcata gcttctcaaa gagttcctta
      421 tgaacatttt tagcaaagga gccggaagcg actgcgcagt ataatgtgag agcagagcga
      481 tcacaccttt ttaagcgact gtagggagta agattcccag ttgagaaaaa tgcgcgaatc
      541 tgtttggaga aaaaagaagt ggttttttag gcgggaaatt ttgtccccct cttttataat
      601 ctctttttaa acctcttttt aaacctcttt accgtcggct atatccttac tctcccaagg
      661 gaatgacgct tttatctaca tcgttttgtc tgtttatcta catcgttttg tctgtttatc
      721 tacatcgttt tgtctgttta tctacatcgt tttgtctgtt tgtacattga attagtacat
      781 cgacgatgtt aatataagat gtagataaac aggcattttg tatttcataa cgtgtatctc
      841 ttgtgcgagt aagaaaggag ctattttaaa tatgtctaat gaaatcgtaa agtatcatca
      901 tgaattaaat acaattccgt tgcgaaaatt tacaccagtc gaaatgaatt tgttcttttc
      961 tatcgtatca agaatgcgtg atgtaggtga taaaaaagta caatttacat tcgagcaatt
     1021 aaaagattta agcaattata aagcaactgc aaatgttcga ttcatagatg atttagaaac
     1081 aacgtatgac aaattaatgg atttacgttt tggtagaaga agtgctgacg gtttgcaacg
     1141 tgaacgtttt gttttattta atcaatttaa aatcgacgga aaatctgata ttccttttgc
     1201 tgaaatacaa gttcatgaaa aagccttacc cttacttaat aatcttgaag aatgggtgcg
     1261 ctattctctc caacaattca atgaattaga aagcagttat tcaaaaacaa tgtttcgatt
     1321 actaaaacaa tacagaacca aaggtttcgc ttatttttca aaagaagact ttcatgaatt
     1381 acttgatatt cctaaaagtt acaaccaagg tacgattgat caacgtgtgt tcaatccaat
     1441 acgacaagaa ctaaccgcaa tctttaaagg tttaacaatc aaaaagaaat acggaaaagg
     1501 acggggaaag cctgtcattg gctatcaatt tacatttaaa cctgagataa aaaaatcaga
     1561 cgactttaac aaacatgccc caacaaaaga agaacaaaac aaagcattag aactagctaa
     1621 ccaacaagtt caatctgaaa aagcacctac ttcattacaa gaaaaaatca aagaacaaaa
     1681 gcgaaaattg gaacttttac aacagttaga aaagttagaa agagaacaaa atacccaaaa
     1741 taaagaaaat aatgcacaaa aatcagagat aaattccgat attccttcag aactaaaaaa
     1801 agacttatta gacaatcttc aaaacttatt caaagattga ggggttttta gattttatga
     1861 cagaaaaaac aatcaaagaa cttgctgaag aattaggagt tagtaaaaca gcaattaaca
     1921 aaaaagtttc tgacgaaaat cgaaaacttt ggttttcgaa aatcggaaac aagtttgtga
     1981 ttaatgaaac cggacaaaag gctataaaat caatgttttt taacgaaaac gaaaactcaa
     2041 atcaacaact agttggcgaa aaaacgaaaa ccgaaaacca caaaaacgcc aaccaagttc
     2101 ccgaattaga agtcctttct ctcctagaac aacagttaaa tcaaaaagat atgcaactac
     2161 aagaaaaaga cgagcaaata aaacaaatgc aaaaattact cgaccaccaa caacaactca
     2221 ccctgcaagc caaccaacaa atcgagaaac tgcaggaaca actacagttg acttatacgg
     2281 aagaatcttc ggaaaataaa tcaacgactc tttctgaaga aacagaatcg atagaaaaac
     2341 aatcaaaggc ggagaaaaaa tggtggcaat tctggcaata aaaccagcaa tttaaattaa
     2401 taaaaattgc tggttttatt cttctttttg cttttgcgag cagagcaaca tggacccatg
     2461 ttgcgatatt ttggtggcgc cccaatcccc gttttttcgt tgaatcttac tcggactgca
     2521 ctcgttttac agctgatttt tctgaatttt gaaagagcat aaggaaacgt ggtatcactt
     2581 tcttacgaaa ggtgctagat aggctgtgcc tatcacgttt ctcagaaaaa aatttgctat
     2641 cacttttttg ccattgtggc taggctatgt atagtgtttt ggcgaaaaat agctatacaa
     2701 atactatatt tgtatggtat acataaatta tacgctgata cgaaaggaaa atttccatgg
     2761 acattttagt tcgaaatatc aatcccaaaa ttattgcaag aatagataaa cgttgtcagg
     2821 aactcacaac caaaacgggc aaaaaatgga gtcgaaataa atatctaaaa gttctaatcg
     2881 aaagtgattt tgaccgtcaa cttatgaatt acaaaaaaga tcaattcgat ttattactcg
     2941 aaaaatttat tgccattcaa acagaaaata cgaacatact gaatgactat gttcacacaa
     3001 acaaccaact cattgaaaca cttatcggag gaatataaca tgagaaaaac ttctgttcaa
     3061 aaacacgtaa ccctttatcc cagtcacgtt gacgttttag attccatcat cgaaaaaaat
     3121 ccagacgtca acaattattc agaagccatt cgttttttat gtatgagtta tgaacctgat
     3181 accaatacaa ccacaaccag taaccaagca aaactcaatg ccatgggaaa agaaatttct
     3241 atcatgacag aaatcatggc agaatttgct gatttatatc taaaagatac tggtgttctt
     3301 atcggtacaa attctaaagt gtatcaagaa gtgaaagaaa aaattgaaaa tcaactcaat
     3361 ccttcccgac gaaatcaacc caaaaatcgt caaaaagaaa ccaatcaaac ctttacttct
     3421 ggaaattttg acccaacaaa ctttctaaaa agataaaaaa agaaaccgat ccctaaaaaa
     3481 attcctcgat ttctttttag ggatcagtct tccagcaaga tttgcaagtt ggtaccaact
     3541 tgcgaaaaaa aagaaaaatc cgcttatgca acttcttctt tttgtatttt ggggcgctac
     3601 cccaatcccc aagtatcggt tatttaatag cgcggaaatc caaagaatag gacgtaccct
     3661 gaaacaaaaa aagactgctc tcacgagcag cccaaaatga gattatccta ttcatcaaca
     3721 taaaaatatt acaaagtgaa gaactagaga aagacaaaaa aagcatatca aatcctctca
     3781 aaaataacaa gtctttaaaa aatgacagat aaaaatgcac aaagaactaa aaaagagaaa
     3841 tcgcgtaaaa tcaagcatta gaagctagta actagctaga ccaattaaaa atcacaaagt
     3901 gagcgtctct atccattggt agaggggcta cttggtctag tcgacattat gttaactagc
     3961 tcgataaata acgattatgt tcccaaaaca atattttatg aactataaca aaaatttgtt
     4021 atcgcatatt gtatatttta attatataat tataggtgta taccacttaa atttaacaca
     4081 aagacgtgat tattttgaaa cccaaaaaga aaatttatct aggtctcctc ttttccttga
     4141 tgattggaat ttttagtata ggaattacaa atacctatgc ttcagaaaat tctaatttca
     4201 atatcaactc ccaaccaatt gaagaacaag caattaattt tgcgaaaact gattttgaac
     4261 actccataac ttcaattctt ttaatggaaa ataacaccga aactgatatt aactatactc
     4321 ttggttcgcc atttaaaatg ctcgatggag aaaatacggc aaatagttct attttctttc
     4381 cagtattttc agacgctgat aatacgatta aatatattta taccgtcaaa aaaaatacaa
     4441 atggagaata ttcaggaagt atctcacaat ttttagcaaa agaacttcaa aatctagtag
     4501 atagtaatat aacagataca accttatttt ttcaagataa tagcatttat tattccgata
     4561 atggacaaat taaactactt tggaaatcac ctttaagtac agaaaaaaat ggtgtttctt
     4621 cctttacaga aaaaaatgat cttatatccg taaatataaa aaataaaatt aaaaatttct
     4681 ctaaaaaaca aaattttcct gcggttaaac gtgtaaaaag tgtctcctcc ggagataact
     4741 ttattatgat taattggcgt atagcagaaa cccaaacaag ttttccgtgg tgtgctgctt
     4801 acgtagaagc tgctatctta tgtaacaaaa cagatgtacg tgctacttca gctagagcca
     4861 ttatgcatta tacctatcct aatttaaaca acagtcaaat tgaatcaaaa agtcttaatc
     4921 aagatcaaat aataaaatat gcaaattact gtggtgttta tcctaaaaaa gtagcacgaa
     4981 tactaaacct ttcagaggtc caaacacaac taagaaaagg aaatgccatt tatatgggaa
     5041 ctgctggtta tggaaattat agtaacagcc gtcatgcact tgcattattt gggtgggtca
     5101 atcaaggtgg ttatcaaact tactatgtgt ggaatccttg gtataactac ccaactgtaa
     5161 taagtgcaaa tgcaggacca gttacaattc ctgtacctgg aggtggtttt acttgggaca
     5221 ataccattac aaattggtaa ataaacccat tgctttagtt atgggtctag tgttagttct
     5281 tttcttaact agttgttcaa aaaaacaaga aatacaaaag actgatctga ttccttttct
     5341 aggaacttgg caaactaaag atcattcaga acgtctagta atcactaatt taaatacttc
     5401 aaaaaatata gaacaatata ccatcttagt aaaagagaac aatcataaaa ttcaaatcat
     5461 tgataaaaat ttaaatataa atgaacaagt tttcatttac aaagcaacaa ataatttact
     5521 aacactgcgc tctaataaaa aacaattaga ttacactttt agtttggatt ctccaaaaaa
     5581 gctcgtattt attttgacaa cgaatgatgg gacagaaggg acagctaaac caattgaatt
     5641 ttttaaagct gattgatgaa tagttgtttg atattacaaa acaataattt caccgaaggt
     5701 gaaacaagcg aaactttaca aaaagtggct agcatttgct agcc
//
LOCUS       DADQCX010000130         5726 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.135, whole genome shotgun sequence.
ACCESSION   DADQCX010000130 DADQCX010000000
VERSION     DADQCX010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.135"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            195..920
                     /locus_tag="J8R83_002558"
     CDS             195..920
                     /locus_tag="J8R83_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575667.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            910..1419
                     /locus_tag="J8R83_002559"
     CDS             910..1419
                     /locus_tag="J8R83_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575668.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1489..2937)
                     /locus_tag="J8R83_002560"
     CDS             complement(1489..2937)
                     /locus_tag="J8R83_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9575669.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2937..3653)
                     /locus_tag="J8R83_002561"
     CDS             complement(2937..3653)
                     /locus_tag="J8R83_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9575670.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3634..3984)
                     /locus_tag="J8R83_002562"
     CDS             complement(3634..3984)
                     /locus_tag="J8R83_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAZ9575671.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4128..4901
                     /locus_tag="J8R83_002563"
     CDS             4128..4901
                     /locus_tag="J8R83_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9575672.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5072..5438
                     /gene="ssrA"
                     /locus_tag="J8R83_002564"
     tmRNA           5072..5438
                     /gene="ssrA"
                     /locus_tag="J8R83_002564"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1661 a         1124 c          994 g         1947 t
ORIGIN      
        1 aaattattgt cgctgctcct cttttcgaat aaacagtgtt caaaagcttg catctacggt
       61 aatagaatag ggcagcttct tcacaacctc ttgcttttta caaaatattt tctggtttta
      121 attcgtgatt tcactaaagg aatttcatac tttattcata ttcattttct atacttttta
      181 tagaggtgaa aagtatgaaa ataatccgct atgctactgc tcgattaatt tattacaaaa
      241 agcagacaat actctattgt ttattttcaa gcttttctgc ttttttattg atagcatgcc
      301 tgactcttta ccattcgcaa tcggctttag ccaatcaagt ccaagatcgg ctttcattta
      361 ttggcgcttc tgcatctaca gagcttcttc cggctttaga attagctagc cgattttata
      421 taaaaggcat attcagttta ttttttctat ttgccttcct ttttatcttt ttcttttact
      481 attcagtcag gcaaaacaag caggaattga tcaattggcg cctgactggt ctttctaaaa
      541 ccaaattatt cctttttatt ttctggcagc tgttctttcc tctctttctt tgttgtatct
      601 tggttttatt gtggatcgtc agcttccagt cagtttatga agcgcttctt caaaggatca
      661 attttcttgt cttaaagact actgaactgc cagatatccg tgatatcttg acttcggtaa
      721 gcggacttac aattccgatg gatcaacaga ctttttttac catcgatttc caaaatgatc
      781 tttttttcac agatatactt aagggatttg cccaaactct tattgggctc agtggatgct
      841 gtctcattct tagtctattc cctttcactt tttttatcca tcatttgcaa agtaggaggc
      901 ctggacgtaa tgaaacctga atatttgatt catgctgaac acttgaccgt tattttgtgt
      961 cctctcgaaa aacagcataa aatattggag cacttgaaaa aagaggttct tgttgcaaaa
     1021 ctggataatt ttgcgatcat ccaaaaaaat tggccgatgt ttccttatct gaatcttaaa
     1081 gaccatgtcc tgttggatgt accggaaaaa gaaatcaaac aagatcgttt ggcctatcaa
     1141 gaaaaacttg atatctctcc ttccttgctt aattgtgcgg cagctgagtt gacgtctttt
     1201 gaaaaagtaa agctgcaatt acttcatgcc ttgctttcca agcgaaacaa tattgttatt
     1261 gaagatacat ttgatgaact tagtgtattg gagatccaag agctactcca cttgctttct
     1321 tatttagctc atgaagaaaa tcaaggtatc ttactcttta ctcatgatgc tactattgct
     1381 caaagtcctt atattgatcg tttagagccc gcgggctaaa tcaatcattt tatagtaaaa
     1441 acaagcggta tagaagatcg attcatgatc ttttataccg cttgtttttt actctttttt
     1501 gatttctacg tcaggcaaac gaacagcgaa ttttgttcct tttcctagtt cgctttctac
     1561 ttctaatttt cctttatgca agcgtacaag ttgctgcacg attggtaaac ctaatcctga
     1621 ttcaccatat tttgtatttt ttcttgaagg atctacttta taataacgat cccagatact
     1681 tttcatttgt tgttcagaca ttccaattcc cgtatcttca atcgtgatga tcgtttcaag
     1741 atagcctttt tctaaagtaa tcgtgatttg gccgttttca gtaaactgta tcgcgttttg
     1801 aataatattg accatgattt ggacaaatcg gtcataatca gcgtaaacat caatatcatc
     1861 aacggctttc aatgtcaatg tatctcctgc tgcttctgct ttagcttcta actgtgcaac
     1921 aatatttttc aatgtttctg ttccattgaa ttttttaatg accatactga tttgattcgt
     1981 acggattttt tcataatcca agttttcatt caccaaacgg atcagacgct ctgtttcatt
     2041 tttcatcaat ttaatcgcgt tttctcgctg attttcaggg attgcattgt attctaaccc
     2101 ttccagaagt ccgttgattg tcgtaagagg tgttctcatc tcgtgagaag catctgccat
     2161 aaattgtctt cgacgatttt cttgttcttc aatttctgct tgagattctt tcaatgaatt
     2221 cgtcatttta ttgaaatcat ctgctaactc atcaaattca tctttgtcat gtacggggag
     2281 ctgtacatca aaattaccat tcgtcacttc tttcgtcgca ttccttaacc gattgatacg
     2341 cttaacttgg aatgctgcaa aagcatagct ggcaataact gcaacgatac tggaaaaaat
     2401 aaatcctttg aacaggttca gtgtaattgg acgaacgctg ttatcgatat ttcgcgcagg
     2461 ttgactaact acaagtgctc catagaattc atgattcaaa ttaaatggca caagtgcgta
     2521 agaggtcgcc tgtgcttgtc ctaaaatatt tttattcgat gtgaattttt cttgacgtcc
     2581 attcctcaga tttttccatt gatcagctgt taaggtaaaa ttcagtaaag ctgtattagt
     2641 cggataaatg acacgttcgt ttttatcgat aaatataaag ttcacatttt gttctgtcag
     2701 tacttgctct gtcagcagca atgcattttg aaacgcctga tcttgactaa actgcgggag
     2761 cgtatcggca taggtttgcg ttgtcttttc aactgattca gcatatccaa acagttgctg
     2821 gtaattgttt tcttcaatcg tttgttttgt cagttgtgta aaagaaactc caacgatcaa
     2881 taagatcaac gcgaccattc cgcaaaaagc taagagttgc tgatacaaat aacgcattag
     2941 gcaacaccag aatcatcgaa tttgtagccg actccccaaa cagtttggat gacttgtggt
     3001 ccgacctttt cgattttttg tcgtaatttc ttgatatggg cgtccactgt ccgttcatca
     3061 ccaaagtact gataatccca gactaattca agcaactgct cccgagagaa tacttgacgt
     3121 ggtttttttg ctaaagtaaa caatagatcg aactctttag gcgtcagtcc ttcaattggc
     3181 cggttgtcca gatacgcttc tcgtgttttc gtattcatct tgaaatgact agtctcgata
     3241 tcaaaatgat catctgaaac tgctgcttct tctcttgctt ctgccaactc actacggcga
     3301 tgcaaagctt tcattcgagc aataagcgtc agaggactga aaggttttgt gacataatca
     3361 tctgccccca tctctaagcc gatcacctga tcgctttcag aatctctagc tgtcagcatg
     3421 ataatcggca cagtacttga aactttgcgg atctctcttc ctactagcat accgtccagt
     3481 gtgggcaaat tcaggtctag tgtaatcata tcccaatgtt gtgggttttc taaaaaggca
     3541 tcgagccctt cttttccatc atacttgaaa gttgcttccc aaccttcatt taagaaaaac
     3601 atctgcatca tttcagaaac agattgatta tcttcaatca ttaaaatatt cattatcgtt
     3661 ccctccagtt tccaggtcat atttctgtaa tttcttttct gtcataataa aaataggcat
     3721 aattggaaat actagcagaa gcatttcaat cagaaaataa ttcgtatgcc cagatgtctt
     3781 taaataatag ccgatcaatg ccatcagtaa gcccataaga aaaaaccagt ttccgcttgt
     3841 cttttgagcc agccgccaat gagcgtctgt ttttgcggca agaggcgaat gatacccata
     3901 aaaaggcaga tttccttttg agggcagaat ccgaaaaaga ctgccaatta ttaagaataa
     3961 gataccaata ctgaaaaaaa tcattctttc cctcctaaat tctcttctta tagtatactc
     4021 taaattgttg actgaaccaa tatgttcagg aattcttcac gaaaggtttg tcttttgttc
     4081 attctttgtt aagataaact tattccaata aaaaaggagt tttatttgtg tcaaattatc
     4141 gtgcaatcac tttctttgat cttgatggaa cattactaga tgcgaaatca aaaatcacac
     4201 ccgaagtggc aaaagctatg aacgcattaa aagaaaacaa tgttctcccc gtcatcgcta
     4261 caggacgtac agaagcagaa atccactcta tcatggaaga tgcgggcatt acttctgcgg
     4321 tcaccatgaa tggttctttc attcgagtag acggcgaaga aatctattct caaacatttt
     4381 cttcagaaga atgtcaaaaa atgtatgatc atgtacagtt gaacggtcat gaactttctt
     4441 actataacga tcagaaaatc tggtgtaccg gtcatagcca aacaatgatc aatgcttacg
     4501 acttcattca ttcagatgtt ccggaaattg atcctttagg ctttaaagaa aacacagtaa
     4561 atatgttgct gatcttatct caatcaggtg acgaatacta tcacgaacat tttcctgagc
     4621 taacttttta tcggaatggt ccttactcga tcgatacagt gaagaaagga atctcaaaag
     4681 gggcaggtgt caaacgtctg caaaaagaac ttcagctgga aaaagttcct acttttggat
     4741 ttggcgatgg tccgaatgat tttgccttgt tggaagcttg cgacaacaaa atcgctatgg
     4801 acaacgccta tgacggatta aaagaacttt ctacctttat cacaaagaaa aatacagaag
     4861 gcggaattgt ccacgcattg aagtattttg atctgattta agatcttttt ttgaagctac
     4921 ctcttttctt aagaaaatcg cttatttttt cttaagaaag gggcagttat tatataaata
     4981 atgggatatg attcgctttt ttattgaatt tatcccaata tatgctatac taattttgta
     5041 tgaaaaatac acgtaaccct tgttagctaa cggggacgtt acggattcga caggcacagt
     5101 cgagcttgaa ttgcgtttcg taggttacgt ctacgtaaaa acgttacagt taaatataac
     5161 tgctaaaaac gaaaacaact cttacgcttt agctgcctaa aaacagttag cgtagatcct
     5221 ctcggcatcg cccatgtgct cgagtaaggg tcctaacttt agtgggatac gtttcaactt
     5281 tccgtctgta agttgaaaaa gagaacatca gactagcgat acagaatgcc tgtcactcgg
     5341 caagctgtaa agtgaatcct taaatgagtt gactatgaac gtagattttt aagtggcgat
     5401 gtgtttggac gcgggttcga ctcccgccgt ctccatatat gtatggttga gacagataaa
     5461 catgtatgaa aaacgttgtt aaatcaacgt ttttttattt tggtcaagga gagaaaagta
     5521 gagaaataca aaattttttg cattgatttt gcattcaaaa aaacattcaa acatttagaa
     5581 atccccaata cgtattcagg aaaatctatt ttaaggttta caaaaagaac ttttgttcgt
     5641 acactctttt tgaggtgaac ttttatgctg atggaaggaa aaacacaatt atggtttaag
     5701 catgttcctt caaataagtt ttttta
//
LOCUS       DADQCX010000131         5665 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.136, whole genome shotgun sequence.
ACCESSION   DADQCX010000131 DADQCX010000000
VERSION     DADQCX010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.136"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(72..542)
                     /locus_tag="J8R83_002565"
     CDS             complement(72..542)
                     /locus_tag="J8R83_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAZ9575673.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            872..2512
                     /locus_tag="J8R83_002566"
     CDS             872..2512
                     /locus_tag="J8R83_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAZ9575674.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2666..3988
                     /locus_tag="J8R83_002567"
     CDS             2666..3988
                     /locus_tag="J8R83_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAZ9575675.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(4056..4490)
                     /locus_tag="J8R83_002568"
     CDS             complement(4056..4490)
                     /locus_tag="J8R83_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575676.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(4555..5391)
                     /locus_tag="J8R83_002569"
     CDS             complement(4555..5391)
                     /locus_tag="J8R83_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAZ9575677.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
BASE COUNT         1696 a         1128 c         1038 g         1803 t
ORIGIN      
        1 gcaggttttt cacgacctct gattcacggt gtttcttttt catcaacatt tttacgaaat
       61 actgtggaag actattgaaa taagtgtgga ttgtttcttt gtgtttcaat cgtttcttgc
      121 cattcttcat ttaattttgg attaccgttt tcttccttga actcataagg tcctaattca
      181 aaaatcccag acagtatttg attcacgatt tcatatagtt cagtgtgatc agacacatga
      241 ttcttgaaga tcatctcatt atcaccacgt ttgaacctca cattcgggct ctcatgatga
      301 acctctatgc atttttctcc tttttttaac tgacggactt ctgaaaacat ctcataaata
      361 tcttctccag taaaaccttc agcaagcgcc agactgtcca caagaccgcc tactgtcagt
      421 tcagagatta ttgcttgatt ggaatctaat tttaatgtat agcttgtcgc ttctactacg
      481 ccacatgcat tgcaaccgcc ttctgatagt tcgctttttc taatcaattg aacttctttc
      541 attttctctt cctcctctta attttctact tatgtatttt tatcacctga cataggtgac
      601 tcctatcaac gctatcatgt gcttttttcc tcagaaatcc tatttatcca ttccatctat
      661 cccttattct tctacttttc tttctctagc atataagaga tacgcatagt attcaagcaa
      721 ggattgtcga tataaaaaga acaaatactg ctattttgat ttcttttggc tatattacat
      781 ataaataaaa tttatcatac ctgctctttt tgactatatc atcatctgac ttctatactt
      841 cgtttgtatt aaaacttagg aggaatcatt catgcttaca gggttaaact tattaaataa
      901 tccttttcta aataaaggaa cagcttttac aaaagaagaa cgggcaaaat atggaatcac
      961 tggtatgctt ccaagtactg tccaaacact ggaacaacaa tctgttcaag cttatggtca
     1021 atacttaagc aaacaaacag atttggaaaa acgtatcttc ttaatgaatc tattcaatac
     1081 gaatcggaca ttgttttata aattgatggg cgaacattta gttgaattca tgcctgtcgt
     1141 ttatgatcct gtcgttgcgg attcaatcga acaatacaac gaaattttct tgaaaccgca
     1201 agatgctgca tttctttcaa tcgacgaacc agaaaacatc aaagcaagtt tgaagaacgc
     1261 ggcagatgga cgagacattc gtttgattgt tgtgactgat gcagaaggaa tcttaggtat
     1321 gggcgactgg ggtgtgaacg gtgttgacat cgctatcggc aaattgatgg tctatactgc
     1381 tgctgctggt attaatccag cacaagtttt gcctgtatcg atcgacgctg gtactaataa
     1441 tgaagaatta ttgaataatc ccttatactt aggcaatcgt catgctcgtg tagaaggcga
     1501 aacttactat gaattcatcg atcaattcgt tcaatcagct accgaattat tcccagaatt
     1561 gttattgcat tgggaagatt ttggacgagg aaatgctgca gcgatcttag aaaaatacga
     1621 agatcaaatc actactttca acgacgatat ccaaggtaca ggaattgttg tcctagcagg
     1681 tgtattaggc ggattgaata tatccggtga acaattgaaa gatcaaataa ttttgacatt
     1741 tggtgctggt actgctggtg tgggtatcgc aaacatcctt ttagatgaga tgatccgtca
     1801 aggtgtacct gaagaagaag cacgccaaca tttctatcaa gtagataaac aaggtttatt
     1861 gtttgaagat acagaaggat tgactcctgg tcaaatccca ttcgctcgca aacgctcaga
     1921 tttcactaat gctgatgaat tgacaaactt agaagcagtt gtaaaagcga tccatccgac
     1981 aatcatgatt ggtacttcta cccaacctgg agcattcact gaagaaatcg tgaaagaaat
     2041 ggctgctcat acaccacgtc cgatcatcat gcctttgtct aatccaacaa aattggcaga
     2101 agcaaaagca aaagatttaa tagaatggac ggacggaaaa gcattagttg gaacaggtat
     2161 ccctgctgct gatgttgaat ataatggtgt aacttaccaa atcggtcaag caaataatgc
     2221 tttgatgtac ccaggtttag gacttggttt gattgcttca acagctacac gagtaaatgc
     2281 tgaaatcatt tctcaagcta gtcgagcatt aggcggaatc gttgatgtaa caaaaccagg
     2341 agcagctatc ttgcctccag tagcaaaaat cactgaattt tctcaaacga ttgctgaaac
     2401 tgtcgcaaaa tcagttgtcg cacaaaactt gaatcgtgaa gaaatcacgg atatcaaaga
     2461 agcagttgaa tctgctaaat gggttcctga atataaatct ttagaagatt aagatcgtta
     2521 tagtaaaaga acatacagaa actttgtatg acgtctaaaa agaaaaaagc gactgcggca
     2581 aaacagcggc cagccaactc ctgctctttt gtcgcttttc tttggctttt ttcatatgat
     2641 acagaataag aaaggatctg taaaaatggc acaaaaaaca acaactgcaa ctgcagttga
     2701 ggaaaagaaa aaagaaggtt tttggtccac aaaaatcacc ggcgtaagtt tgccacttta
     2761 tttgatcatg gtccttgtcc tgatcattgc aatggcttta gggaaattac cgacgaatat
     2821 gattggacca atcgcagttt tggttatttt cggtaattta tttcatttta tcgggacaaa
     2881 aatccctatc gtcaaaagtt atttgggtgg tggttccgtt tttgcgatct tcgcttctgc
     2941 tgcgattgct acatttggga tcttacctga atatgtagtg aaatccacag aaaactttgt
     3001 cagcaatatg ggcttttggg acttttatat tgctgccttg attactggta gcatccttgg
     3061 tatgaaccgt aatctattga tgaaagcttc tgttcgtttt attcccgttg cacttatttc
     3121 aatggtcgtc tccttttttg ccgtaggact cgtgggcatg cttatcggaa atggttttgc
     3181 aaattccgtt ttatacatct cattacctgc gatggctggt ggtgttggag ccggagccgt
     3241 tcctttatca acgatttatg caaatgtttt aggtacggat gcttcttcta tcatttcccg
     3301 cctgattcct gcgacagcaa tgacaaatgt cttagctatc atcggtgcag cattagttgc
     3361 tcgtgctgga caatcaatgc caaaattcaa cggcaatggt aaattaatgg aaaaaggcga
     3421 tcttggcgat ggaaaacctc gaactgtgaa accttccatt ccacagttag gtgttggttt
     3481 gatggtatca ttgactttct tcatcttagg acaaattggt aactattttg ttcctaaagt
     3541 ccatgcttac gcatttatga ttattatcgt tgtcatctgt aaaatcgcca acctattacc
     3601 agagtattat gaagatgcag ctatcatgtt caataacttg attgtcaaaa acttgacagc
     3661 agctgttctt gccggtatcg gtattgcgtt gctgaatctg aatgtattag cttctgcttt
     3721 gacatggcaa tttgttgtct tatgtctgac aagtgttatc gcgatttcag ttgtttcagg
     3781 atttgtcggt cgtttgtttg gtttatatcc aattgaatca actattactg ctggcttatg
     3841 caacaactcg atgggcggaa caggaaatgt agccgtctta tctgcagcta atcggatgga
     3901 acttattgct tttgctcaaa tgggcaatcg acttggtggt gccatcgttt tgatcatctc
     3961 tggtttcttg atgcaattac tttcttagtc aaaaaaacaa aaatacctga tcatcaagta
     4021 tcggcttggt gatcgggtat ttttttgata aagatttaca ggattttcaa aaatcttttt
     4081 tgcattttat cggaatgata accgatgtgt tcataaaatt ggtgtgcttc tactctgtat
     4141 tctgcagaat taagccttat tgtcgttatt cctcgttttt tcgcttcttc ttctacgcca
     4201 gtcatcaaag cctttccgat gcctcttttt tcagcatatt tagacacagc aagtgccata
     4261 atattgaaca ttggatcgct aaaaatcgat tcataggact ccgcttgtac atagccagct
     4321 gcttttttag aagtaggatc ttcataaacc aagaaaaaat ttttctctgg ctccttcagc
     4381 agtttcttca tttgtctcac cgtaacggtt aatggtatat cataccctaa ttgatccgca
     4441 ttgatttcac gtagtgcttc tgcatcttct aaacgcattt cccgtaacat ccaaatcacc
     4501 agccaatttc tgatttttta aaatgaattt ttttatcata gtatactctt tttttcattt
     4561 agaacaatat gtttcagtga ttttgacttg cgttagtcta gattctccta atgtttgtaa
     4621 gatgacaaag gcattgtaac aattgaccaa aagaaccacg aggacaatta cttgaaaaat
     4681 aaaggtcact ttttttggag acaaaaccct gctaaatctt gctccccaca aacctccaat
     4741 aacagcagcg gggataacat aaaacaacat agataaatca aagcgcataa agctacttgt
     4801 taaagcaatc gttaccaatt ttgccagttg agaaaagaaa atcgtagata gagaatatag
     4861 tgttgcttct tttattggca atgcaaacat cagcatcaac aaagaaacat tgactggtcc
     4921 accaccaata cctaaaaaac tagctaaaaa gcccagaacc cccccacata taaggtacca
     4981 agtccatgac gtcaaatgaa attttggctg atgatgcttg gtgtagaaga acgcaaaaac
     5041 caaggtcaat accgtcaaaa aaatttggat cagctgcaca tgcttctcgt tttcaaataa
     5101 ctgtaaaaaa acttcgaata caatgttgcc gactactcct ccaacaacag ctccactaga
     5161 tacccaaccg acaatctgcc aattcagtga tttcccgctt gatacttgtc gcacagtcga
     5221 aacaatggac atcgtgaata ccgcaactgt tgagtaaaaa gaaatccctg caacagaatg
     5281 ggcgccgata agatcaagaa tcggtttgat caacacgcct ccacccatcc cggaaatagc
     5341 gccaactgtg ttcgccagaa cgatcaccac aaaataaatc agaccaatca tcttgtattt
     5401 cctttctctt gtttatatct tttagcgatt gttactcttt tcttttatta tacagtaaaa
     5461 gaaacaaacg aggcttcgaa agcttttcta ctttttaagg aaatttagtg ctaaacgaaa
     5521 agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagctc
     5581 ctcataattt tcgtttggtt gaacttatta ccgcagatgc aagcttttga acaccgttta
     5641 agaaagaggt cgtgagcctg ccgtt
//
LOCUS       DADQCX010000132         5220 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.137, whole genome shotgun sequence.
ACCESSION   DADQCX010000132 DADQCX010000000
VERSION     DADQCX010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.137"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..360
                     /locus_tag="J8R83_002570"
     CDS             4..360
                     /locus_tag="J8R83_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575678.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            376..726
                     /locus_tag="J8R83_002571"
     CDS             376..726
                     /locus_tag="J8R83_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HAZ9575679.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            755..1534
                     /locus_tag="J8R83_002572"
     CDS             755..1534
                     /locus_tag="J8R83_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HAZ9575680.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1545..2222
                     /locus_tag="J8R83_002573"
     CDS             1545..2222
                     /locus_tag="J8R83_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HAZ9575681.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAMILG
                     AIFPAVN"
     gene            2241..3347
                     /locus_tag="J8R83_002574"
     CDS             2241..3347
                     /locus_tag="J8R83_002574"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HAZ9575682.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3337..4428
                     /locus_tag="J8R83_002575"
     CDS             3337..4428
                     /locus_tag="J8R83_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HAZ9575683.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4441..5181
                     /locus_tag="J8R83_002576"
     CDS             4441..5181
                     /locus_tag="J8R83_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HAZ9575684.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
BASE COUNT         1668 a          861 c         1248 g         1443 t
ORIGIN      
        1 atcatgatta aagtagttat tgcagaccgt atgggtaaag gacaaaatgt ggccaaaggg
       61 gtagaagcag ctggtggaaa agcagttgtc gtaccaggaa tgggggcaga tatgcgtttg
      121 ggcgatgtga tgcaacaaga gcatgcagat atgggtatct ctttttgtgg tagtggtggt
      181 gcaggtgcat taacagcagc aacaaaatat ggctatccag aacgacatgg tatgcgttcg
      241 attgaagaag ggatcacagc tatcaaggat ggcaaaactg ttctaggttt cggctttatg
      301 gatcaagagg aattagggaa acgtctgaca gaagaattta tcaaaaagca tggaaaatag
      361 aaagagggac atgaaatgag cgttcaaaag acaattcagc aaaaagttat cgtctccggt
      421 aaaggggaaa caaagcaaca tgcttttgca tcagcgttag cagaaattca aaacaaaata
      481 atggaacaat caaacgtatt attgcgaatc gaaccagtca atgtggatat tttaaaggcg
      541 gtcgaaaaca aatacacaga acgctttcta tttttcttct tcccacggca acgtattagc
      601 tatgaagtcg aactctctgt tactgtggct gtaacagaaa taaaattggc agacatatcg
      661 ttcagccagc aaatgactga agatccaaat gggattgcca ttccatttgt aactaaaaaa
      721 atctaatttt gaatcataag ggggaaagaa taacgtggat ttcgtaatca ttctagtcaa
      781 atcggtcatt atcgggggat tacttggttt tgcagcatct gtcggggcag ctcgaatgtt
      841 tcatgcacct aatacacaag gtttaggagc ttttagaaca ttaggcgaaa tgaatgcctg
      901 catgggtgat ccagcttctc atttttcatt tggtttaggc tttttcttta atgcatgggc
      961 ttcttcagtt ggtgctggtg cattcacaca agatgtgacg catcgaatca ttcccaattg
     1021 ggcagcggca gcacttctag caaaaaacaa agatgtcacc cagaccatgc atgatccgaa
     1081 aaaaatgggg atcattggag cggttatcgg ggcagtggtg gtagccttct taaacacaac
     1141 agctgcagca attccagagg cgttacaagt gacggcggtt tccgttttgg taccagcagc
     1201 gacgattctg atcaatacag taatgccagt tattttttgg ttggcagctt tagacgcagg
     1261 gaaacgaact ggtttttggg gcactctttt tggtggtatc gcgcaattga ttatgggaaa
     1321 tgcggtacct ggtgttgttc taggaatctt gattggtaaa ggcgtcgatg agagcggttg
     1381 gaatcgcgtc acgaagagca tgatgatcgc tattgtttta ttatttattt tcagtggatt
     1441 tttccgtgga tttgatatgg aaatgatcaa gagcttccag cttcaagtgc ctaattggct
     1501 tgataacttg cacaacatct ttagtgtgaa ataggaggag aatcatggag acaacagaag
     1561 aacaagcaaa agtattagaa gcaaagcggc aaaagagctt ttggtttgca gactggtctt
     1621 ttccgctaat cgtaggaatt atgtccgctg ctgtatttgc aggaacacac atgtatgtga
     1681 tgtatggtgt gggtgcattc aatgaagttt cgatcgtggc gatgttaaaa gccgggctgg
     1741 atggcggatc ctatggcgca gcggcagcgt ttggtgctag tttcttattt gccagaattt
     1801 tagaaggctc tttagttggg atcttggact taggcggttc gatcctaact gggatcggaa
     1861 ttggggtacc agcaattctc ttaagtatga aaatagcggc accaatcgat aattttgcac
     1921 tctctttatt gactggtttg gttctaggtt tgattgttgg tggcatcatt gtcttgattc
     1981 gtaaatttac gatcaatcaa tcaaattcca cttttggtgc tgacgtcatg atgggggcag
     2041 gaaattcatc tggacgtttt ttgggtccat taattatatt aagcgcgtgt gcagcatcta
     2101 ttccaatcgg cattggcgct acattaggag cactaggatt ctatgcttgg aaaaaaccaa
     2161 ttgctggagg tgctatttta ggagcaatga ttttaggagc aatcttcccg gcagtaaatt
     2221 aatagaaaga gggtcattaa atgtttgata ctttgattaa aaatggaagg ttagttgatg
     2281 gatctaaaat agaggtcgct atagaaaaag gcatgattaa agcagttgca gcagaaataa
     2341 atcagccggc gcaagaagta gttgacttgg agggaaagta ttatttatcc gctgggtgga
     2401 tcgatgatca tgtccactgc tatgaaaaga tgaatcttta ttatgactat cctgatcaga
     2461 taggggtcga aaaaggtgtg acgacggtca ttgatgctgg aactacggga gcagaaaaca
     2521 tccgtgaatt ttatcaattg acgaaatcgg tcaagacaaa tgtgtatgcg ctaatgaata
     2581 tctctaaatg gggcattgtc aaacaagatg aacttgctga tctaacaaag attcaagaag
     2641 atctagtaag tactgcgtta gcagaactgc cggaatttat tgtcgggatt aaagcgagaa
     2701 tgagtaagac agttgttggt gaaaatggca ttaagccatt agaattagct aaaaaaatcc
     2761 agacagaaaa caatgatctg ccattgatgg ttcatatcgg ttctgcacct cctgagttag
     2821 aagaagtatt gtcaagaatg gaaagaggcg atgtattgac ccattgtttt aatggaaaac
     2881 caaacggtat tttagatcca aagacagatc aaattaaaaa ctttgtctgg gatgcttaca
     2941 ataatggtgt cgtctttgat attggacatg ggacggatag ctttaatttc catgtggcag
     3001 aaaccgcact aaaagcagga atgaaagcta cctctattag tacggatatc tacatccgca
     3061 atcgtacaaa tggcccagtt tttgatctag caactacttt agaaaaattg agggtagtcg
     3121 gctattcttg ggaagaaatc attgaaaaag ttacagcagt tcctgcacgg aattttcatt
     3181 tgaagaataa gggccagtta gctgtcaatt atgatgcaga tttgacgata tttgagattg
     3241 ttgaaaatga aaaggaattg aaagattcca acggatttac acgtatagct aaagaacaaa
     3301 ttttaccgat taaaacaatt attggaggcg tcatatatga caattagcta tggaaagttt
     3361 gatttaaaag aagtcattaa tgcatcggga aaaatgacga tcctaggggt ttctaaggta
     3421 tctgaaagtg tcctagcagc acaacgattt ggaggcgagc atttttttga gatgagtgat
     3481 cttgccatca aaaccggcgc ttatctttct caattactga aagtggaaga tgcgcaaatc
     3541 gtttcttctg cttcagcagg gattgctcaa tctgttgctg ctttaatcgg acagggcgac
     3601 atgtaccatg tctatcatcc ctatacagaa aaaatcgcta gacgggaaat catcatacct
     3661 aagggacata atgtagatta tgggacaccg gttgaagtaa tggttgctca aggtggagga
     3721 aaagtcatag aagctggcta tgcaaatatg tgtacaccgg aacatgtttc catgatgatt
     3781 acggaaaaaa ctgctgcgct tctatatatt aaaagtcatc atgcagttca gaaaagtatg
     3841 ctgacggtgg cagaaatggt agaagttgcc aaagctcatc gtttgccatt gatcgttgat
     3901 gcagctgcgg aagaagattt attcaaatat agcgaaatgg gcgttgactt agtgatttac
     3961 tctggggcaa aagcaatcga aggtccgagt gccggactgg tcataggaaa aaagaagtat
     4021 attcaatgga ttcggctaca gtctaaaggt attggccgag caatgaaaat cggtaaagat
     4081 aatattttag gctttaccca ggcactagaa gattatttaa aaaatgggag cgaatccggt
     4141 gactccatga agcaacgatt agcgcctttt gttaacgcaa tcaatcaact tcctgacctt
     4201 tcagcgaaaa tagttcaaga tggtgccggc agagatattt atcgagcaag tgtaacgatt
     4261 aatggcgata aaagtgcgaa agaagtcatt caggaattaa aagcacgaaa tccagcagtc
     4321 tacacccgag aatatcaagc aaataacgga atcattgagt tcgacattcg ttccgtcagc
     4381 caaaacgaaa tggaaaaaat tataaaaaga ttgagagaaa tcatgtagga ggcttttaaa
     4441 ttgtcagtta tcccaaatta ttataaaaat cgtgtatgtt taaatgtatt agctcattca
     4501 gttgaaaatg caaaagcatg ctatgaagca gcggaagggc atgtcgtact aggtgtgcta
     4561 tcgaaaaatt atgctagcga tgaagcagca atcgaagata tgaaaaggta ccaagacgca
     4621 accaataatg cgttgtcagt tggattaggc gctggagatc caaaccaaag tcagatggtt
     4681 tcgcgtttat ctggggtttt acaaccacaa catgtcaatc aagtatttac tggcgtgggg
     4741 acttctcgtg ctttattggg ccaaaatgat acagtcatca atggattggt ttcaccaaca
     4801 ggtaagatcg gctatgtcaa tattgctaca ggtccgttaa gttcacaagc gccagcagct
     4861 gaagtgccta ttgaaactgc cattcaaatg ctgcaagaca tgggaggtac ttcaatcaag
     4921 tatttcccga tgaaaggctt agcacatagg gaagaattta aagcagttgc ggaagcttgc
     4981 gcaaaatatg aattctattt agagccaaca ggaggaattg atctttcaaa ctttgaagaa
     5041 attctgaaaa ttgcaatcga tgcaggtgta aaaaaagtga ttcctcatgt ttatagttca
     5101 attatagata aagaaacagg agatacgcgt ataggagacg taaagatact attaagcatg
     5161 gtaaaaaaaa ttattcacta actcattaga aaataagaag cttattccag aatgaaatta
//
LOCUS       DADQCX010000133         5208 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.138, whole genome shotgun sequence.
ACCESSION   DADQCX010000133 DADQCX010000000
VERSION     DADQCX010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.138"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(44..259)
                     /locus_tag="J8R83_002577"
     CDS             complement(44..259)
                     /locus_tag="J8R83_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAZ9575685.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            483..1283
                     /locus_tag="J8R83_002578"
     CDS             483..1283
                     /locus_tag="J8R83_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9575686.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            1302..3170
                     /locus_tag="J8R83_002579"
     CDS             1302..3170
                     /locus_tag="J8R83_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9575687.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            3163..3654
                     /locus_tag="J8R83_002580"
     CDS             3163..3654
                     /locus_tag="J8R83_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAZ9575688.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            3642..4196
                     /gene="srlA"
                     /locus_tag="J8R83_002581"
     CDS             3642..4196
                     /gene="srlA"
                     /locus_tag="J8R83_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAZ9575689.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            4214..>5208
                     /locus_tag="J8R83_002582"
     CDS             4214..>5208
                     /locus_tag="J8R83_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAZ9575690.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1825 a          826 c         1067 g         1490 t
ORIGIN      
        1 gaaggttcat gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa
       61 cttttctagt aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga
      121 tataaatgat cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa
      181 gttcgaacaa gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa
      241 tagcatctaa agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca
      301 aaaagagaaa cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga
      361 aaattttttt tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc
      421 ttaatttttt ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac
      481 atatgtcgga ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag
      541 gaattggaag aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg
      601 atgtaactga atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt
      661 ctaaaacgga catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg
      721 gtctagtcaa taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa
      781 aaagcaagta tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa
      841 gtgtatattt gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga
      901 tcgtgaatct ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg
      961 ctacaaaagc agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga
     1021 atgttcgtgt ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag
     1081 aatatgaaga agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt
     1141 acagtcgaac aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc
     1201 tagtctgcta ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt
     1261 caggaggtaa aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat
     1321 ggtaccaatt attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa
     1381 aagaaatcaa aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa
     1441 ttgccggtat tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt
     1501 ttgatttttt tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg
     1561 catccaaaag aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta
     1621 tggatgattt gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga
     1681 cattaaaaga gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac
     1741 taagaataat aggagatgag ctagaattac gactactttt attttatttt gtttctccct
     1801 acttttcaga gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc
     1861 agaagaagac gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt
     1921 ctttgaatag aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt
     1981 gttttgaata tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac
     2041 taactttgag ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa
     2101 gtataacgat gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga
     2161 tgcgtattcg acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga
     2221 aacagcacct ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat
     2281 tttatggtga gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac
     2341 aagcattaga agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt
     2401 tgtatttgga gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca
     2461 ttgttcatac gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat
     2521 tggggaggga tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa
     2581 acaaatattt cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg
     2641 tgatccattt gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa
     2701 aaaaaaagcg attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa
     2761 aaaagacgta tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg
     2821 tggatgaaga atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta
     2881 acaaagaatt tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag
     2941 tagggctaat aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat
     3001 ttgccatacc tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata
     3061 tcctatttga actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag
     3121 aatcattttt aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta
     3181 ttcatagttt tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta
     3241 aagcatttca atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa
     3301 cgacctggga aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa
     3361 gttttagaag tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct
     3421 gtctatgcgg gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa
     3481 gatcgtttga cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca
     3541 ggaaatgaaa aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg
     3601 atatggaaaa gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat
     3661 ttgctgaggg atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga
     3721 caggaatcgt accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt
     3781 taggtgaaga ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt
     3841 accttgtgtt accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg
     3901 ctcgtttcct tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc
     3961 atacgagcaa tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga
     4021 ttgctcaagg gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc
     4081 ttgtgggact gctgatgaac tttattggtg gttggataac tgattttact actggatttg
     4141 tatgcagaca gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa
     4201 aggagagttt taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg
     4261 tcctttgatt attaggccga caaaagataa acacaagttc atctatgtca caggtggagg
     4321 tgagaggcca atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg
     4381 gttcaaaaca tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac
     4441 tcttagatgt ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg
     4501 aaaaagtggc ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt
     4561 agaacaaata cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc
     4621 tccagataaa aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca
     4681 gcaaaactgg atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca
     4741 atcagcaaga gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt
     4801 ttcccttttg attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat
     4861 ggcaccttta gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc
     4921 atttttatct cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat
     4981 cggtgtagag attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc
     5041 tatcaatact caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa
     5101 agctgagaca gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat
     5161 cccacgagtt atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DADQCX010000134         5128 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.139, whole genome shotgun sequence.
ACCESSION   DADQCX010000134 DADQCX010000000
VERSION     DADQCX010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.139"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..708
                     /locus_tag="J8R83_002583"
     CDS             <1..708
                     /locus_tag="J8R83_002583"
                     /inference="COORDINATES: protein motif:HMM:NF025056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HAZ9575691.1"
                     /translation="KKLENNSKEDLFTSKNYVQWMTDVNYIFKTDLKNSIFKDEFEKA
                     YFYKNSRLKNSLYEIISILELIMSKSEGEITSMKEKIFISHSSKDKELAKEFVNFMKT
                     SFEINNRKIFCTSLNGSLGVGDNFITKIKKEIAESAIIIFLITPNYLSSKFCLCELGA
                     AWALDQNIFPILCESASIDDLNATPLLGTQCVKLDDEENMIDLAQMIVSTDLADSQSL
                     LDYKGNLKNFLKLIDAK"
     gene            754..1896
                     /locus_tag="J8R83_002584"
     CDS             754..1896
                     /locus_tag="J8R83_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9575692.1"
                     /translation="MFFENKLWYIVHEGDVFMNSDLFKIIEGGIEKDTQKVINYSKKL
                     AEQFYLEGKTSTGKKIERIIAENNTRVSSLDSLTSRPTDRDTKVDLVDVWIPFETGDT
                     LYFDSIIEKEIKNFTLTYYNRNRLIDHGIESSNNLLLYGPPGTGKSSLAKYIALQLKL
                     PLITVRMDGVISSLLGSTAKNIRKVFDYASKQPCILFLDEFDVIAKIRDDQSEIGELK
                     RVVNSLIQNIDSFSEDSILIAATNHSHLLDNAVWRRFDKVLFIRIPEYNTRKDIIVEF
                     SNRIENNFCNDSKKLDVLTSLTENFSPSQIKTTIGNSIKKTIVSGDELLKFSEVVYAI
                     FLEINQEDAVNDVDIIKFLHSNNISQREIAEQFSFSLRKVKDCLSN"
     gene            1911..4256
                     /locus_tag="J8R83_002585"
     CDS             1911..4256
                     /locus_tag="J8R83_002585"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HAZ9575693.1"
                     /translation="MDSKKSRLISFKQRDQDNLKVGPSPQTQVPTWVLSGADLDRKTK
                     FLIEKLDVIENNFPRFSTQELPDVLSVSFIEDAKAKTHQRKILDLMGSELNGRQIGMS
                     DDNSILLEFLSKDGIAKIKENIDSDQEKYKVSISAIEDFTPYKAKKNLNEKNKNNYLL
                     EFFDYSDKKMNENTFKYVEHLLKKNNIKFEEKIYNEDILLQIDNSSIKDALNLVENDS
                     IPIKSINPIAKTEVSPFRNVLAEAEEESMWVSYDEEKEYPIIGLLDSGVDMNSQTSQW
                     VVKGSGCNIPDEELDTSHGTFIATLLIHGNRYSNYTDCSVDGCRIVDVPIVPRYSIPE
                     NELINNIRDAISNNPEVKIWNLSVSLVEQIDQNSFSTFAIALDEIQDEFKVLICKSAG
                     NDRSFYAGSSAGIISKGAESLRSLTVGSILRNSDNFGFCKKGFPAPYSRIGRGPANII
                     KPEVVHFGGDVFALNAAPTSVEDYQSQGETSYLNAVKRIEAGTSFSTPKIAKSLSEIN
                     NSLIDSDLLLSKTLLIHSSTYFNNPDMKIEDKIKALGFGYPKKSSDILVEDTEYRTTM
                     ILKGELRKSNFIDIMSFPFPKNLLRDGHYYGKIKITLCYDNILDKRMASEYSQSNITL
                     RFGTFEKIEEVRPFANQKVPTNPFKRIGSKNVLLENRYSVNSMRNNTEYASERKLIKG
                     DFKYHSTKQYSIDLSETKPSKLSDLESDKSWFLYMSPEFRNPALDKYSSDQLKMNFCC
                     IITIEDPFKENNIYEGVIKSLEENNFEYNNIEINQDLSINL"
     gene            4760..>5128
                     /locus_tag="J8R83_002586"
     CDS             4760..>5128
                     /locus_tag="J8R83_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HAZ9575694.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEV"
BASE COUNT         1949 a          648 c          880 g         1651 t
ORIGIN      
        1 aaaaaacttg aaaataattc aaaagaagat ctatttacaa gcaaaaatta cgtccaatgg
       61 atgactgacg taaattatat ttttaaaacc gatttaaaga atagtatttt taaagatgaa
      121 ttcgaaaaag cttattttta caaaaatagt agattgaaaa atagtttata tgaaattata
      181 tctattttag aactgattat gagtaagtca gaaggagaaa taactagtat gaaggaaaaa
      241 atttttataa gccatagtag taaagataag gagttagcta aagaatttgt aaatttcatg
      301 aaaacatctt ttgaaattaa taatagaaaa atattttgta cctcattgaa tgggagtcta
      361 ggagtaggag ataattttat cacaaaaata aaaaaagaaa ttgctgaatc agcgattatt
      421 atttttttaa taactcctaa ttatctgagt agtaaatttt gcttatgtga gctaggagct
      481 gcatgggctc tcgatcaaaa tatttttcct attttgtgcg aatcagcaag cattgatgat
      541 ttaaatgcaa cacctttatt aggtacacaa tgtgtaaaat tagatgatga agaaaatatg
      601 atagatttag ctcaaatgat tgtatctact gatttagcgg atagtcaatc tctattagat
      661 tacaaaggta atctgaaaaa ctttttaaaa ctaattgatg caaagtaaag cagtttttta
      721 tggaacgaaa aagcaatata tgggaacaaa tatatgtttt tcgagaacaa attatggtat
      781 attgttcacg aaggggatgt atttatgaat tctgatcttt ttaaaatcat tgaaggcggt
      841 attgaaaaag atactcaaaa ggttataaat tactcaaaga aactagcgga acagttttat
      901 ctagaaggga aaacatctac tggtaagaaa atagagagaa taattgcaga gaacaatacg
      961 cgcgtttcct cgttagattc actaacttct agaccaacag atcgagatac aaaagtagat
     1021 cttgtcgatg tatggattcc ttttgaaact ggcgacacct tgtattttga tagtattata
     1081 gaaaaagaaa taaaaaattt tactttaaca tattacaaca gaaataggct aattgatcat
     1141 ggaattgaaa gttcaaataa tttattgttg tatggaccac caggtactgg taaatcttct
     1201 ttagcgaaat atattgcttt acaattaaag cttccactta ttactgtaag gatggatggg
     1261 gttatttctt cacttttagg aagtacagca aaaaatatca gaaaggtatt tgactatgct
     1321 tctaaacaac cgtgcatttt attcttagat gaatttgatg tcatagctaa aatacgtgat
     1381 gatcaaagtg aaattggcga gcttaaaaga gtggtaaata gcttaattca aaatattgat
     1441 tccttttcag aagatagtat attgattgca gctaccaatc attcgcattt gttagataat
     1501 gcagtttgga gacgttttga taaagtattg tttattagaa ttcctgaata taatacacga
     1561 aaagatataa tagtagagtt ttcaaataga attgaaaaca atttttgcaa cgattcgaaa
     1621 aaattagatg tactaactag tcttacagaa aatttttctc catcacaaat aaaaactaca
     1681 ataggaaatt caataaaaaa aactatagtt agcggagatg aattgttgaa atttagtgaa
     1741 gtagtgtatg caatattttt ggaaattaat caggaagatg ctgtgaatga tgttgatata
     1801 attaaatttt tacattctaa taacatttca caaagagaaa ttgcagaaca gtttagtttt
     1861 tcactgagaa aggtcaaaga ctgtttatca aattgaggac gtgatactat atggattcga
     1921 aaaagtccag attaatcagc tttaaacaaa gagatcaaga taatttgaaa gttggaccat
     1981 ctccgcaaac tcaagttcct acctgggttt tgagtggtgc agatctagat agaaaaacta
     2041 aatttctaat agaaaaatta gacgtgatag aaaataattt ccctcgattt tcgactcaag
     2101 aactacctga cgtactatca gttagcttta tagaagatgc aaaagcaaaa acgcatcaaa
     2161 ggaaaatatt agatctcatg ggctctgaat taaatggtcg tcaaataggt atgtcggatg
     2221 ataacagcat attactagag tttttatcaa aagatggcat agctaaaatc aaagaaaata
     2281 ttgatagtga tcaagaaaaa tataaagttt ctatttctgc tattgaggat tttactcctt
     2341 acaaggcaaa gaaaaatttg aatgaaaaaa acaaaaataa ttatctcttg gaattttttg
     2401 actactcaga taaaaaaatg aatgaaaata cttttaaata tgttgagcat ctgttaaaga
     2461 agaataatat aaaatttgaa gaaaaaattt acaacgaaga cattcttttg caaattgata
     2521 attcttctat aaaagatgcg ttaaaccttg ttgagaatga ttcaattcct ataaaaagta
     2581 taaaccctat cgcaaagacg gaagtgtctc cctttcgaaa cgttttagct gaggcggaag
     2641 aagaaagtat gtgggtatca tatgatgaag aaaaggaata tccgataata ggtcttttag
     2701 attctggtgt tgacatgaat tcccaaacta gccaatgggt tgttaaggga agtggctgta
     2761 atattcctga tgaggagctt gatactagtc atggtacttt tattgccaca ttactaattc
     2821 atggaaatcg atatagtaac tacactgatt gttctgtaga tggctgcaga atagttgatg
     2881 tgccaattgt gccaagatat agtattcctg aaaatgaatt aattaacaat attagagatg
     2941 ctatttctaa taatcctgaa gtaaaaatat ggaatctatc tgttagttta gtagagcaaa
     3001 ttgatcagaa tagtttttct acatttgcaa ttgcattgga tgaaattcaa gatgaattta
     3061 aagtattgat atgtaaatct gctggaaatg ataggtcatt ttacgctgga agctctgcag
     3121 gaataattag caagggtgct gagtcacttc gttcattaac agtaggatca atactgagaa
     3181 atagcgataa ttttggcttt tgcaaaaaag ggtttcctgc tccatattct cgcattggga
     3241 ggggacctgc aaatattata aaacccgagg tagttcattt tggaggagat gtatttgcac
     3301 taaatgctgc tcctacaagt gtagaagatt atcaaagcca aggagaaaca tcatatttaa
     3361 atgccgtaaa aagaattgaa gccggcacga gtttttctac tcctaaaatt gcaaaatctc
     3421 tatctgaaat aaacaatagt ttaattgatt ctgatttact tttatctaaa accttattga
     3481 ttcattcttc aacttatttt aataatccgg atatgaaaat tgaggataaa attaaagcgc
     3541 taggttttgg ttatccaaaa aaatcttcag atattttagt tgaagatact gaatatagaa
     3601 cgacaatgat tttgaagggt gaattaagaa aaagcaattt tatcgatata atgtcttttc
     3661 cttttccaaa aaacttactt agagatggac attattatgg taaaataaaa atcactcttt
     3721 gttatgataa tatattagat aagcgaatgg caagcgaata ttctcagtca aatataacac
     3781 ttaggtttgg aacttttgaa aaaattgaag aagtaagacc ttttgctaat caaaaagttc
     3841 ctactaaccc cttcaaaaga atcggttcta aaaatgttct tttagaaaac agatacagtg
     3901 ttaattctat gagaaacaat actgagtatg cttcggaacg aaaactgata aaaggtgact
     3961 ttaaatacca tagtaccaaa cagtactcaa ttgatttgtc tgaaactaaa ccatcgaagt
     4021 tgagtgattt agaaagtgat aaatcatggt ttctatatat gtcaccagag tttagaaacc
     4081 cggcattgga taagtatagt tctgaccagt taaaaatgaa tttctgctgt ataataacta
     4141 ttgaagatcc atttaaagaa aataatattt atgaaggcgt tataaagtct ttagaagaaa
     4201 ataattttga atataacaat atagaaatta atcaagacct gtcaataaac ctgtaaaaaa
     4261 actagaccta tttttaggtc tagttttttt acaggtttac ataagataca ttatgcgaag
     4321 ttcattattt taaaagctta aataataaac ttttttataa taccaattta tttatgtaaa
     4381 ccaatgacct taatcgctta agcaagcatg ttatgtaata ctctactctc tccaaaacta
     4441 atgactatct attttcaaag aagctagaat gattatctga tcaaatgata atttatattt
     4501 aattcctggt ctactgctct tcttttaatc aattaatgtc taacgtactg tacacgataa
     4561 agtaggaaga cttattttca acttcggatt cattttttta attcggtgaa aatcactaaa
     4621 ttaagagttt atccaagttc attttagctg agaatacgct tgaaaataat tttgatgaat
     4681 tttcctgaat taaaatttat taacttgttg agtgatataa ttgtaatgta ttaccaaata
     4741 gttagcactt agattagtga tggaaaggaa tagtgagaac aagatgactg gtagaaatcc
     4801 caaagtattt atatcatatt catgggagaa taaggaaaat aaagaatggg ctagagaact
     4861 agcagacaaa ttacttgaaa acggtattga tgcatatata gatcagtatg atttaagttt
     4921 aggtgataga ttacctcagt ttatggagca gcaaatatcc gattcagatt atgttctaat
     4981 tatatgtaca ccagagtata aaaaaaaggc aaataatcgt acaagtggtg ttgggtatga
     5041 aggtcatatt atctcagcag aattgctttc tggaaaaaat gaacgtaaat ttatcccaat
     5101 aattaaagaa ggacgtgcaa gcgaagta
//
LOCUS       DADQCX010000135         5005 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.140, whole genome shotgun sequence.
ACCESSION   DADQCX010000135 DADQCX010000000
VERSION     DADQCX010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.140"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(50..1204)
                     /locus_tag="J8R83_002587"
     CDS             complement(50..1204)
                     /locus_tag="J8R83_002587"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAZ9575695.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            1389..3830
                     /locus_tag="J8R83_002588"
     CDS             1389..3830
                     /locus_tag="J8R83_002588"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAZ9575696.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(4160..4864)
                     /locus_tag="J8R83_002589"
     CDS             complement(4160..4864)
                     /locus_tag="J8R83_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575697.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         1568 a          922 c         1047 g         1468 t
ORIGIN      
        1 taaaaaaaga acctttcacg actcgtgaag ggttcttttt atgattttat tatattttgt
       61 agtaacgaat atcattttcg atctttgtaa tcgaaaaagg tacatctgaa gtatattctg
      121 cacattctcc gtgttcagga agcgtctcac tgaaaatcgt ttcatattcg tcaacagtga
      181 tccgtgttcg agaatctagc atctcttgat gagattgtgc gaagagatat tcttgatagt
      241 tttcttccag ataacctgta aaaaattcac ttactgcacc agaaccgtag ctgaatagac
      301 cgatgcgatc tcctggctgt agtgatttcg aattttccag tagagaagtt agccccaggt
      361 ataatgaacc agtgtaaaga ttaccgattc gtcggctgta acggatgctt tcttcatagc
      421 gagccataag acgttcctga ttttcttcgt ctgtttggtc taatacgctt tgcaatgcct
      481 tttttcccat cttagtatac ggaatatgga aagcaatcgc ctgataatct tcgagtcctc
      541 gacccgacaa ttctttatgt cgattccaaa ctttttggaa tgattcgata tacgtagaat
      601 tagataaagg accatcaaca acaggaaatt cgctataatc tggacgccag aaatcataga
      661 tatcttctgt cagaaatacg ctgtcgtctt caatcgataa aatacgcggg ttttgagtga
      721 tcatcatcgc aacagcaccg acaccttgcg tcacttcacc accgcttgcc aagccgtaac
      781 gagcaatatc acttgctatg actagtactt ttcgttctgg atgatttttg acatattctt
      841 tcgccatgtg caaagctgcg gtgccaccgt agcaagcctc ttttacttca aaagaacgag
      901 caaaagattg gattttcagt aaatggtgga taattaccgc actcgctttt gaatgatcaa
      961 tcccggattc tgttccgacg atgaccatgt cgattagctc acggtctttt tctgttacga
     1021 ttttgctggc agcatttgct cctagtgtaa tgatgtcttc atttgcacga ttgactgcca
     1081 tttggtcttg accaatccct atatggtatt ttgcaggatc atccccacgg ctttctgcca
     1141 actctgtcat atctaaatat aaattaggaa taaaaaagga aagacgatca atccctattt
     1201 tcatttcaac acctctttac ttatgataaa aaacttactt tactaaggta tcataaaaag
     1261 attaaaagaa atataaaaaa gagaatattt aaggattgtt aaaatttaat cttagaaaaa
     1321 aataactgga acaagagcta tttgttttta cagcaaagaa tggtatattt ttgtaggagg
     1381 tggcttactt gaaagaagtc gttatgatag atgctgcaag aacgccgata ggaaagtatc
     1441 gcggaagttt aagtccattt actgcagttg aattaggcac acttgtgact aaaggattat
     1501 tagataaaac aaaactgaaa aaagataaaa tcgatcaagt aatatttgga aatgtcctgc
     1561 aagctggtaa tggtcaaaat gttgccagac agattgcttt gaacagcggt ctccctgtag
     1621 atgtcccagc aatgacgatc aatgaagttt gcggatctgg tatgaaagca gtgatcttag
     1681 cacgccagct gatccaatta ggtgaagcag aacttgtgat agccggcgga acagagagta
     1741 tgtctcaagc acctatgctg aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa
     1801 tttccagtat ggtcaacgac ggattgactg acgcattttc aaatgcacat atgggattaa
     1861 ccgcagagaa tgttgcaaca caattttctg tgagcagaga agagcaggat cgctatgcct
     1921 tgtcgtccca gttgaaagca gcacatgctg tcgaagccgg tgtattttct gaggagatca
     1981 tcccagtcaa gatttctgat gaagacgtgt tatctgagga tgaagcagtt cgtggaaata
     2041 gtacattgga aaaactgggc acgttacgta cagtattctc agaagaagga actgtaacag
     2101 caggaaatgc ttccccgttg aatgacggtg cctctgtggt gatccttgca tccaaagaat
     2161 acgcagaaaa taataatctg ccttatttag caaccatcaa agaagtagcg gaggtcggta
     2221 ttgacccaag tatcatggga atcgctccaa tcaaagccat tcaaaaattg acagatagat
     2281 caggaatgaa tttatcaaca atcgatcttt ttgagatcaa tgaagcattt gcagcttctt
     2341 ctatcgtagt tagccaagaa ctgcagttag atgaagaaaa ggtcaatata tatggaggag
     2401 caatcgcatt aggccatcca attggtgcaa gcggtgcacg tatcttgact acattagctt
     2461 acggattgct tcgtgaacag aagagatacg gtattgcttc attatgtatt ggtggaggtt
     2521 taggcttggc agtcttgtta gaagcgaata tggagcaaac acataaggat gtgcaaaaaa
     2581 aaaagtttta tcagcttacg ccatctgaac ggcgcagtca attaatagaa aaaaatgtat
     2641 tgacacaaga aactgcgttg atttttcagg aacaaacact ttctgaagag ctctccgatc
     2701 acatgatcga aaaccaagtg agtgaagtgg aaatcccaat ggggatcgcg cagaattttc
     2761 aaatcaatgg caagaaaaaa tggattccga tggcaacaga ggaaccatct gtcattgcag
     2821 ctgcaagtaa tggtgcaaaa atctgtggaa atatctgcgc agaaacacct cagcggctga
     2881 tgcgagggca aatcgttcta tcaggaaaat cggagtatca agcagtgatc aatgcagtta
     2941 atcatcgaaa agaagagctg attctttgtg caaatgaaag ttatccttca atcgtgaaac
     3001 gcgggggcgg tgttcaagat atctctactc gggaattcat ggggagtttc catgcatact
     3061 tatctattga ttttttagtg gatgtaaaag atgcaatggg cgctaacatg atcaactcga
     3121 ttcttgagag tgtggcaaac aagttacggg agtggttccc tgaagaagag attctattca
     3181 gtattttaag taattttgct acagaatcat tggcttctgc ctgttgtgaa atcccattcg
     3241 aacgcttagg gagaaacaaa gaaatcggtg aacaaattgc caaaaaaatc caacaggcag
     3301 gggaatatgc gaagcttgac ccttaccgtg cagcaacgca caacaaaggg atcatgaatg
     3361 gtatagaagc tgtagtggca gctacaggaa atgatacacg tgcggttagc gcttcgatcc
     3421 acgcctacgc ggcaagaaat ggattatacc aaggattaac agactggcag atcaaagggg
     3481 ataaactagt tggaaaacta acggtgcctt tggctgttgc cacagtaggc ggagcttcca
     3541 atatcctgcc aaaagcaaaa gcatctttag ctatgttaga tattgattca gccaaggaac
     3601 tagcacaagt aattgctgca gtagggttag ctcaaaacct ggctgctttg cgtgcattag
     3661 ttacagaagg aatccaaaaa ggccacatgg gacttcaagc tcgttcatta gcgatctcaa
     3721 ttggggctat tggtgaggaa atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga
     3781 tgaaccagca gacagctata caaatattgg aaaaaatccg ggaaaaataa aaaagcaata
     3841 tctttagaag aataaagcaa gatttacagt tattttattt actgcagatc ttgctttttt
     3901 ctctatcaga aaatatgttt attattagaa ttttttatag ttaaggttag gcatcttaag
     3961 aaatcaggca actccaagat atcttcaggt agaagagaag tcgcctaaca ttgtaggatc
     4021 ataggtgatt tgttggacag gtcaagctga tatttgagcc tgatgttaga aggaatttct
     4081 ttttacttgc tgtagaaatt attatatgac taaaaaggct gggattttaa atcccagcct
     4141 tttatgacaa atagaatttt tatcgatcag taatcgctgt cgctgcaaat tgttcgatca
     4201 aaggaatcaa agtcaatttg actttgtatt tccgttcgag tgctttttcg ataacgaact
     4261 cattttcagt agtcatagaa atagttgcta atttacgagg ttcatcagca tttttttcat
     4321 taataactac ttcatgttca ttttgttctg tgtaaaattt aggatactca gcaacggctt
     4381 ttgaaaaatc agcaaaactt aaagcggcat tcgtatcagt tgagcgtgta ttttcagttg
     4441 tgtccgcttt tggtttttcc gttttttctt ctggcacact gactgtttct tctgtaactg
     4501 gtgtcgcaac agcttgcgca gttggttcat cgtttttcaa tcgttgatca ttccagtaag
     4561 acacgatttc aataagaaga ttgtcacgga atcgttcgaa aatcccgttt tctcctgaac
     4621 gaattctctt taatacagta ttgaagttgt catcgattgg cacgttgatc cgtgtatctt
     4681 catttgtttt cccagctaat ccgatcgtta agatttgacg gtttttggga tcaagcatga
     4741 cttgtaacgg caaaccataa cgtcgcaagc tctcttcttc tagagaacgg aataattgtc
     4801 ctcttacacc atccaatgaa ggacggaatt gatttaataa tttttgtttc tgttttttct
     4861 tcatatgttc tctccttcgc tcataccctt tcgattataa gaaaaaaaca gccaaatgaa
     4921 aaggagtaat gcaaaaaaac ttgcgtatac gcaaattaca acagaaaaat ttgcgtattt
     4981 tcccgttttt tgaaagaaaa ataaa
//
LOCUS       DADQCX010000136         4977 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.141, whole genome shotgun sequence.
ACCESSION   DADQCX010000136 DADQCX010000000
VERSION     DADQCX010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.141"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..182)
                     /locus_tag="J8R83_002590"
     CDS             complement(<1..182)
                     /locus_tag="J8R83_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9575698.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="J8R83_002591"
     CDS             517..951
                     /locus_tag="J8R83_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9575699.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="J8R83_002592"
     CDS             974..1294
                     /locus_tag="J8R83_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575700.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="J8R83_002593"
     CDS             1435..1626
                     /locus_tag="J8R83_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575701.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="J8R83_002594"
     CDS             complement(1697..1954)
                     /locus_tag="J8R83_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAZ9575702.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="J8R83_002595"
     CDS             2112..2375
                     /locus_tag="J8R83_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575703.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="J8R83_002596"
     CDS             2399..2587
                     /locus_tag="J8R83_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575704.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="J8R83_002597"
     CDS             complement(2670..2855)
                     /locus_tag="J8R83_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575705.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="J8R83_002598"
     CDS             3070..3441
                     /locus_tag="J8R83_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9575706.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="J8R83_002599"
     tRNA            complement(3591..3663)
                     /locus_tag="J8R83_002599"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="J8R83_002600"
     CDS             complement(3709..4137)
                     /locus_tag="J8R83_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575707.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="J8R83_002601"
     CDS             complement(4197..4955)
                     /locus_tag="J8R83_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAZ9575708.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1734 a          781 c          977 g         1485 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaattctag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctg
//
LOCUS       DADQCX010000137         4903 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.142, whole genome shotgun sequence.
ACCESSION   DADQCX010000137 DADQCX010000000
VERSION     DADQCX010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.142"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            288..695
                     /locus_tag="J8R83_002602"
     CDS             288..695
                     /locus_tag="J8R83_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575709.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="J8R83_002603"
     CDS             709..1110
                     /locus_tag="J8R83_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575710.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="J8R83_002604"
     CDS             1112..1483
                     /locus_tag="J8R83_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575711.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1519..1818)
                     /locus_tag="J8R83_002605"
     CDS             complement(1519..1818)
                     /locus_tag="J8R83_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575712.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1824..2054)
                     /locus_tag="J8R83_002606"
     CDS             complement(1824..2054)
                     /locus_tag="J8R83_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575713.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(2490..3056)
                     /locus_tag="J8R83_002607"
     CDS             complement(2490..3056)
                     /locus_tag="J8R83_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9575714.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(3056..4012)
                     /locus_tag="J8R83_002608"
     CDS             complement(3056..4012)
                     /locus_tag="J8R83_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAZ9575715.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(4012..4668)
                     /locus_tag="J8R83_002609"
     CDS             complement(4012..4668)
                     /locus_tag="J8R83_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAZ9575716.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
BASE COUNT         1642 a          843 c          850 g         1568 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtccggcaca tcagtcacga tatcaaacaa
     1621 aaaatatacg tctttcttca ttctagtttt cgcagcaggg attttaaagt agttcttatt
     1681 agaatagtag agattaatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatc
     1741 ccacacctta taaaaatctt tgacaaatct attcgaagga tcaaatttaa accataattg
     1801 cgtctcatta aaaagcataa ccattactcc gatctatttt taaacttagt ctctacctct
     1861 aatatatatc gagtttttat tttgccttca gagaatactg tttctttttt tgcagttaca
     1921 ggttgtttat tttcggaaaa agctaatata gctaaaattg aaacatccat ctggaattta
     1981 tcttttttac tgctttgatc ataaaagtct gcatattcat cactgatatt ttttctaata
     2041 aattcttcca tcataaaaat cacctcaaaa cgattatacg aacttacgtt cttgttgtaa
     2101 agcgatattt gaggggcaaa aaaggggcat aatttgactg atattaagtt agctattgat
     2161 atatgaatga catacaaaaa tataaaatct tttaaaaatg cttatatatc aatgtttttg
     2221 ccattctttt atatatctgt tatatgtcaa aaaaatgtgt tcaatttcaa tttgtatttg
     2281 aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aatcaaaaac
     2341 agcttctcat gtttttgatt tggttggact tattaccgca gatataagct tttgagcacc
     2401 gtgaataaag aggttatgaa atcaacgctc taacctgagt attagagaaa aaaacgcaaa
     2461 acatatcatt tatgttttgc gttttttatt tatctttttt tctcaataca atataaaata
     2521 ggcggctggt tcttttggtt gataaaccga taattcagca cattatatgt ttcctgtggc
     2581 agtttggaac aaaaagaatc aaccatatcc agttcttttt ctccaccttc atgaccatag
     2641 tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt tcaatatttc ttccatagct
     2701 gtgcgtgtag tctctggcat agtgatgatt gctttatcac tttttgggag ataccctaga
     2761 ttgaaaatcc ctgctttgag attttgttgt tcagctatca cttctcctaa cgtttcgtgg
     2821 ccttgtagaa acaatgagac acgttcttct aactgacgct gttctagcct ttcacgagta
     2881 gcatcgattg cttgttgctg gatatcaaaa ctatagacat gaccagtttt tccgatgtgt
     2941 tctgctagaa aaaccgtatc gtggccattg cccatcgttg catctacgac gtgatcccct
     3001 ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca aagcagtttg caacatcaga
     3061 cgctcacctt tttccgtaca tcatattttc cttggaagct atctctgcga agaagttctt
     3121 catcaattgc attcaagact tcccattttt tcaagctcca cattggtcca atcaaggaat
     3181 cccacggcgc atcccctgtc aaacgatgga tgatgatctc ttttggtatc atttccagct
     3241 ggtcgcaaat gacattgaca tagtcaggac ggctcattaa ttgaaggcga ccttcatgat
     3301 agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa atggagcttg attccttgga
     3361 tatctgaatc taaaatggtg cgtctgacat tttctttcat catttctaaa ctttcgcctg
     3421 gtaatccgtt gatcaaatgc gtacaaacac ggatattatg tttgcgtaat ttagccacgc
     3481 catctaaata agtttgataa tcatgtgctc ggttgatcag ttttgaagtt tcttcaaaag
     3541 ttgtttgcaa tccaagttct acccataaat acatccgctc gttcagttca gcaaggtaat
     3601 caactacttc atctggcaga caatccggtc gtgtaccgac tgataatcct acgacacctg
     3661 gtaaattgac tacttgctca aatcgttctt tgattatttc aactggcgca tgggtgtttg
     3721 taaaattttg gaaataaacg atgtattgtt ggacatgagg ccatttttga tgcatcatgt
     3781 cgatttcttt ctggaattgg attggaagag ggtcttcagg tgcaacgatc atgtctcccg
     3841 aaccagatac actgcaaaaa gtacaaccgc catgggcaac agtcccatct cgattcggac
     3901 agtcaaatcc tccatcgatc ggcaccttga aaattttccc gccaaactca tttcgtaaag
     3961 cgtaattcca agaatgatat cttttatttc cttctgaata aggaaaagtc attaaaagtc
     4021 cttctttctg taagagttat ctatttgttt tcttttttct ctatacactg gataagtcag
     4081 gcacagccaa gaaagactga gtaagtaacc gccgatgata tcagtaggaa aatgaacgcc
     4141 cagataaatg cggcttatcc cgacacttac tataataaac atcatcagca attgaagcaa
     4201 tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga aatagtaaag aaccgtaaag
     4261 aatcatactg cctgctgcat gtccactagg gaaactgtaa cttgtttcaa ctactaagtg
     4321 cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc accgggttga tgattccagc
     4381 aattacaata aatccagaaa cgaaccaaaa tgtttctgcc ctttttttct tataccacat
     4441 ccataaagcc gcacaagcaa ataaaatgat gacggtaaga ggattaccga atttagtcat
     4501 aaagagttgg tagctgttca gatcaggata agaagctctg acaatgcctg taaaccactg
     4561 atcgaaacca gaaagccacg acagatggaa ctttacgatc cagcccaaaa tgaaaaacag
     4621 gacaagaaag aagctaccag ccacctgaaa tgatgtttta tatttcatac aattcctcct
     4681 ttgaagcaat gacttattat agcatttttg gtccagcgaa aaaaacggta aagagataaa
     4741 accaatgtat gattcctctt tgaataacca atattcttat aaaaaaaata actgtaatcg
     4801 gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa ataaaatcag tgtttttcga
     4861 aatcctttta aacaagaacg tagacgtagg aagaacttga aaa
//
LOCUS       DADQCX010000138         4812 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.143, whole genome shotgun sequence.
ACCESSION   DADQCX010000138 DADQCX010000000
VERSION     DADQCX010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.143"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(57..1205)
                     /gene="nagA"
                     /locus_tag="J8R83_002610"
     CDS             complement(57..1205)
                     /gene="nagA"
                     /locus_tag="J8R83_002610"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAZ9575717.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1281..2117)
                     /locus_tag="J8R83_002611"
     CDS             complement(1281..2117)
                     /locus_tag="J8R83_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575718.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2301..3518)
                     /locus_tag="J8R83_002612"
     CDS             complement(2301..3518)
                     /locus_tag="J8R83_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9575719.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3901..3984
                     /locus_tag="J8R83_002613"
     tRNA            3901..3984
                     /locus_tag="J8R83_002613"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3935..3937,aa:Leu,seq:gag)
     gene            complement(4224..>4812)
                     /locus_tag="J8R83_002614"
     CDS             complement(4224..>4812)
                     /locus_tag="J8R83_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575720.1"
                     /translation="FLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYF
                     GNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLI
                     VGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMA
                     VKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1466 a         1001 c          775 g         1570 t
ORIGIN      
        1 aaaaaacctt aaaaccaaac ttaagaagtt tagttttaag gttaacttaa attatattat
       61 gcgtggaaac gttccacgcc atctagataa gttgcttcca atgtcatatc agggttcaat
      121 acgataaagt ctgcatcgcg tccttgagcg atttttccac atgtatcatc gattttacag
      181 ctgattgctg gaatcagact agccatcatg actgcttgtt ctggtgttgc taatccccag
      241 tctacaacat ttttaattgc ttctttcaat ttcaatatac ttccagctaa gttgccagat
      301 tctagacgtg ctgttccttc ttttactact actggaaatt cgcctaaatt gtaatttcca
      361 tcaggcatcc caccggccat catacagtct gtaattaatg cgacatgatc atgtcctgct
      421 ttttccatta ggattcccgc agcatttgga tgtacatgat ggccatcaca aatcaattca
      481 gaaaagacat gttctaaaga taataacgca cccaccatac ctggttcgcg atgattcaat
      541 ccacgcatac cattgaaagc atggacaaat acacttgcgc ctgcttcaac agctttttgc
      601 gcttcttcta gtgtagcatt actgtgtcct agagaaacaa ctactccttc ttcagtcact
      661 tgtttgacaa actcttctac accttgacgt tccggtgcta aagcaatttt tttgattaaa
      721 ccacctgaag cttcttgcca ttcatggaaa gtatccaaat caggatcccc gaaataactt
      781 gggttttgtg cccctttgtg ttcttctgtg aagaaaggac cttcaaaata gattcctttg
      841 attttagctc ctggtgcttc ctgatacatt ttgccgattg tctcagctac atcttttaaa
      901 cgttctttgc ttgacgtcaa tgttgttggt aaaaatgaag tcactccaca agataacaga
      961 ccttcagaca tcactttgat gccttctgca tcattatcca ttacatcatg attcatatag
     1021 ccgtgaatat gtgtatctac caaaccagga gcaatccatt tgccgctttg gtcaatgatg
     1081 ttgacttctc cctcaggtag ttctttggtg tattcaccaa aaagtccatc ggtaatttca
     1141 agatagcctg catgtttgac acctgacgct aaaaagaatt tgtcagcata gataaaagtt
     1201 ctcattctat tctctccctt tgtttttcta cctctaaagt actcttattt agagaagaag
     1261 tcaagaatgg tctacaccat ttacaaattt tttgaaattt gtttcacagc ttgtgctaag
     1321 ccttcataga atgctgctct ttctggttct tctttacgct tgtatattaa gcttttaagc
     1381 acaaataaat cattgaggta atagtagcta ttcttctctt gagcccaata gattccttga
     1441 ttcacctgtt ctaacgcttc gtcgatttca ttttgatgga ataagaaatt tccataatta
     1501 taaaaaattt gcgaaaattc actttttgat cgttcatcag ctgattgatg cagcagttgg
     1561 atgcttcgac tcaaatagta gcgtgcttca gccgtttttc ctgccacacc atatattttt
     1621 ccgatacaac taatcagttg tatttctgtg tcagaaacat ggattctttc tttttggcta
     1681 gagtagctta atgcttcttt caaataataa agggactgag agatattttg acgcaacgtg
     1741 aattcgcaaa caccgagata ataataatag cgttgaaagt cagttgcttg atacagattt
     1801 tcagaaatat cagaagattt tagtacttgt tctaacttcc gataatcacg tttttggaaa
     1861 caactatcca acagttcaaa taatttatcg tttgtccgag tagtttttcg agagagattc
     1921 atcacatgat caatcgttac ccctagccgt tgacaaatct gcatcatcac caatacattc
     1981 ggcagttcct cattattttc gatccgactt aatacacttt gtgaacaaat atcatgcgaa
     2041 agcatttttt gcgtcatttt ttgttctttt cgaatctctt taatgatcgt tccaaaggac
     2101 tcgattaacg tttccataag tatcctcccc aaaatatgcg tattcgcatt ctattcgtat
     2161 tttactttag gaagtcgcaa acttcaagaa aagacttgca actaaataat atactttagt
     2221 tatttaagaa aactccacta gaaagagagc ctcagtgtgt ttgtctgtgg ccctcctact
     2281 gaaaaatttg gtttttaaaa tcatttttgg cgataggttg ctaggaattc tctcattttc
     2341 ttagctgttt gtttcaaatc atccatttta ggaagataaa cgattcgaaa atgatctggc
     2401 tggttccaat taaatccacc accatgtaca agtagaatat gatgttcatg taaaaagtcc
     2461 aaaacgaatt tttcatcatc caaaatattg aatcgctttg tatcaatttt tgggaatata
     2521 taaaaagcag cttttggttt tacggctgaa agaccaggaa tatcattgat tgcattatag
     2581 atatattctc tttgttcata gatccttccg cctggcagga gcagctcatc gacactttga
     2641 taaccgccta gcgcggtttg gataatttgc tgagacaata cattggaaca caaacgcatg
     2701 gaggacaaca tattcagccc ttctatatag cctttgacgt gtgacttatc tccacttagg
     2761 accatccagc ctactcgaaa tcctgctaca cgatgagatt tggatagacc gttcagcgta
     2821 acaacgaaca aatcaggcgc taatgtagca atcggaatat gttctagacc atccatcact
     2881 aagcgatcat agatttcgtc ggaataaata atcaggttat tttgtcgagc tacttcaacg
     2941 atttcttcta ataattcttt tggataaagt gccccagtag gattattagg attaatgata
     3001 acaatagctt ttgtccgact cgttattttt gatttgatat catcaatatc aggataccat
     3061 tctgcctctt catcgcaaat ataatgaaca ggtgtgcctc cagctaatgc aatagaagcc
     3121 gtccacaacg gatagtccgg cattggaacc agtacttcat ctccattgtc cagcaacccc
     3181 tgcatacaca tcgtgatcaa ttcgctcact ccgttgccgg tgtagatatc attgatcgtc
     3241 acattcggaa aatgtttcag ttggcaatat tgctcaattg cttttctagc agaaaagatc
     3301 cccttggaat ctgagtagcc ttctgagtca cgggcattca tgatcaaatc acgaatgact
     3361 tcgtttggtg cttcaaatcc aaaaggtgcg ggatttcccg tgttcaattt taaaatacta
     3421 atgccctctt cttgcatccg ctccgcttct tctagaacgg gaccgcgaac atcgtaactg
     3481 acaccttcta atttgttgga tttttcaaat tctctcatca cttagccaat ccctcatttc
     3541 aaaaagttag aactttccaa attttttgtt atttactatt tcaatatcat actccatcct
     3601 agaaaatttt gccacttatt taggaaaaac gtaagtatta aaaaaacaca aacaagcgtt
     3661 gagaacttaa ttgtcatgat agtcattcca tagattcgct gcccaatcca ttgcaattcc
     3721 acaaatgatt cctagcataa aaccaagcaa aaaacgtccg aatgcaagtc caatcaatac
     3781 acctaagatc attcccagtc ctgaaaattc tccgtcatat ttctccatct taataagtcc
     3841 tcccattttt gagcttgaca actatgtaaa acctcgctat cattagtgtg ttattattac
     3901 gcagatgtgt tggaattggc agacaagcat gattgagggt catgtgagcg ttagctcgtg
     3961 tgggttcgag tcccatcatc tgcactacaa ctcgtgaagt taattttgct tcacgagttt
     4021 ttttgtttga acgtttcttt atgccattat atacatatca ctgtatcctt tacaaaaaga
     4081 acgtacaatc atgtaaacag cctgaggtga gtatatgaag gtcggaaaca agctactcgt
     4141 agaaacttgc aagtgttaaa acaattaatc gaaaaacgag taaaatccct cacctaatac
     4201 taaagcgagg gattttttgt atattatctg tttatcaccg ttattataaa ggtacaaata
     4261 ccaagcacgg ttaatccaaa ttgcataaat tcattttttt gtacactcat gcttttcatt
     4321 agctctttaa ctgccattag tactaagatg gcgataacaa cataaagtat atagtacgtc
     4381 cgcattccgg aagcccatac tgtgggagaa aatcccataa ttaaccttga acaaaatccc
     4441 attatcatca aaataactaa aaaaatagaa gttttcttat tgtcaaaact taaataaatt
     4501 ccaacaatta aacatagtaa taatgccaag actactaaag tagctatcca agtacctgga
     4561 taaaaaagtg acagtttcgt tcctaactct gtaaagagat tattcaggtt actactactc
     4621 caaatcattg cccttttatt tccattgacg taagtaaagc tttgacccat tgtattacca
     4681 aaataaataa tcaggtttaa gaaaaacggt aatgcagtca atatacgcac ataatagttt
     4741 tgacatttcc tatatgttag aaggaaaatt aagaaaaata gcaataaaaa taagatattc
     4801 atgtctaaaa aa
//
LOCUS       DADQCX010000139         4810 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.144, whole genome shotgun sequence.
ACCESSION   DADQCX010000139 DADQCX010000000
VERSION     DADQCX010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.144"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(92..1177)
                     /gene="xerS"
                     /locus_tag="J8R83_002615"
     CDS             complement(92..1177)
                     /gene="xerS"
                     /locus_tag="J8R83_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAZ9575721.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3253..3771)
                     /locus_tag="J8R83_002616"
     CDS             complement(3253..3771)
                     /locus_tag="J8R83_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAZ9575722.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1580 a          786 c          731 g         1713 t
ORIGIN      
        1 atataaaaat gataatgaag cttgccttta aagttgggct tttatctaat tttagagaca
       61 ggcttcatta ttatactatt ttttactaca tttacaaagc gttcaaagca tcaattgtag
      121 ctgcattgtc tatatgagta tataaagttg ttgtatttgt acttgtatgt cccaattgtt
      181 gggcagttaa taccaatgaa tttgtctgtt gatagagtct agtagccaaa gtatgacgta
      241 atttatgtgg actgacttgg actctgaatc cttttgaata ttttgctacc atccgttcga
      301 ttgcaatacc ggatatacgc ttggcttctc cttgataaat tgctagaaat aaagcttttt
      361 cgttttctgt tactttgtat cgttctttcc gaatagctag ataattagct aaatattcca
      421 ttgcaaatgc tgctatattt actgcgtctc tcttatttcc ttttctagtt actaccacat
      481 tattcttttc taaagatagg tcctctaaat taatatttac aacctcggag agtcttaatc
      541 cagatcctaa aatcaatgca ttgatcgcca ggtctctttc tacatctcgt tgataataga
      601 tcaaagctcg tttgctcaaa gtttttttat attcattggc aatataatct agataatttt
      661 gtgtatcttc gtctagaaat aattttttct cgattgcgtt tgcacgggca gctaacgtag
      721 ttttatctgt gatagttgct acttgatcca taggattatt ttctaagtat ggttttccta
      781 aaggattatt ggaacttttc gaaagatatt taaatagaac ctttaatgct gtgatatttc
      841 tattgatagt agaagtagat agacctaagt tattattatc tttgagctta gtttttgttg
      901 tctctttttt tacattttcc tttgtgcgac gtttcaaatg agatttgtac aagtttagat
      961 cataggcagt taactgtctt atcgaggtga ttgaagtatc gggaacgata gactcactca
     1021 gaagccattc ataaaagagc ttataatttt ttagatattc taaagtagtt cgaggtgatt
     1081 gatctttatc ctcacgatct tgaacaaaat cttttatata atcgggcata tgaagtatga
     1141 ttgtatctat tttttgatat atttctgtat ttttcatgtt attcatcctt tcgataagta
     1201 ggggagagga gtatctctat aattggacta taccaattat agagtgtttt gtcaattggt
     1261 atactctgaa atttattaat ttatttcaaa aaagcagata aataggtata gatttaataa
     1321 tttaaaataa atggtataca tgaataggaa aggaaacaga aggaggcaat cttaattttt
     1381 taaattgtct aaattatata gaaagaacaa tctttctata taattagaca taagagggac
     1441 tacggttgat ttgatattaa caagcgtata tgaatgtata tacaaataaa aaaggggagg
     1501 gagaagttaa agaaaattca gagaagtggg gcactcagta gtattaacaa tttaaaagga
     1561 atttcttaaa gaaaatgggt tgcatcctgg agatacaatt tttttagata aagaaaaaat
     1621 tcaagcaaca attcaaaaaa atcttaactg ctgagattga tgtagcaata tctcaatcat
     1681 caacaaagta cgatcctgcc tttcaaaagc ttattgataa atgtttattc attataaaaa
     1741 taaaagaaaa atttatgtca gcttttttca tcaaagtggt aatgataatt cgtctattaa
     1801 ttgtattttt taggaaatat ggtataattg ttttaacgaa aaggtaattc atgatacacc
     1861 aaaaaccact agctggcggg ctagtggttt tcttttacgt tctattcaga ttaacgggta
     1921 ggcttactgt cttttttggc aataattttg caatcaagcc atttacagat gtaatgcgcg
     1981 gatacttctg ctaagattgc aaaaaacata tcgaaaaggt aattcataat acaacctcct
     2041 ccccttgcca taataggccg gggtagcaga cagcataaat attataccat aactgaaaat
     2101 ttcattttag tacatttcaa tatattgatg aaccagcaca ataaaacatg ccatgactaa
     2161 cagaaaaaaa cttattaaac cagatataac ttgtaaacat ccaactatat agaaaacgta
     2221 aattttctat atagttggat taagataacg actatttatt ttatcatatt tttactatac
     2281 cctatacttt tacttggtat atttatgaat aatcgcaaat ttacccctat actactagtt
     2341 tgtaagttag attaataaaa atactaaagt tatttgttct tttattaaat acacctacaa
     2401 cttataaatt gatggtattt agataacacg aaagaataaa aataacagct gatagtaaag
     2461 tttgttgacg attgctactc aatcgaaagt gagttagtgc gtatgaactt gcttctgaaa
     2521 acttatgaaa tgaaagacct tttacatctt gcagaaatcg gtactgggat taaactaagc
     2581 aataaaaact aatgttcccc tcattctttg aacttctact atttgattta tttattctga
     2641 taaatgacga tttcaccttc aggatcttca aatcccgtat agaatttatt taagatctct
     2701 tcagtatcag taataggata ggcgataggc cacataccct ttgatggtta gaataaactg
     2761 ctcaaaatct gtatcgtatg ttggctttag catattaaca aaggctatct ccaaattata
     2821 aaccataagc gttgaatcgt tcttaacaat ttcaattctt cctaacccaa agtcagaaga
     2881 tataattacc ggacttgcct tacccttcat gtgggttgtt gagattccat atttaaaggg
     2941 aattgtcggt actatcggcg gtctgaaaaa catcccaaaa ataaaaaaat ctttcccctg
     3001 ctagtctcct aagtcccttt gtagcggata tggcaccata atctcatttt atcgaagtga
     3061 gtcatggttt atctgttggc caaccaaaat tgatacaatc taacgatgca ccctctacgg
     3121 cattctaggg gagtgcactt gcattcaccc aataaaaacc ggcagttagc aaagaactta
     3181 tgtagtcgta tgttcttact gttaacatac aagaggtctc ctttccacaa ttgcttagca
     3241 gtaaacggga atttacaaag ctaatctctt ccattttctt atctttgttc taaaagtccc
     3301 aaatggagca actgtattta catgaataaa tttatatact tcccatacag ccgttttggt
     3361 tgcctcgtct gcccattttc ttttgtgtgc agtgaataga tcttcatcac tcattgaatc
     3421 aatcatcatg ttaatatcat caatattacg attgagaatt tcctctaatt ctttcaatgg
     3481 tagatgtgca taggtatttg taaaccactt atataactct cctaactgat tccatttaaa
     3541 ttgatcagaa ggcgttttaa cagataatcc atttctttca tcattttccc attttagaat
     3601 taaattcgtc caaccaactt gatatgctaa attttcagca ggtgttctat ccacttcctc
     3661 aactctttta tccttcaatt cttcaggaat agtttcaaat tctaaaatat atttagtata
     3721 agtcctattt atttcttttt ttaattcttc tttattttta tatgttctca ttatattacc
     3781 tccataaatt cctaattgtc tcctttaatt catctataat ttcatccacg atattttaat
     3841 ccgttctaca atgcatatct gatatgcatt gactgtctaa ctcatatgtg aatgatttat
     3901 aaaatatccc aacgtctcat ctaaagaaat gttgatcgtc agcaaggagc taaaaaatac
     3961 gaatatattt cttttgtagt aaaatcggac tggtttgcat atcattttct tcgtaaatat
     4021 caaaatcatg ttaactacta tcaattacta ataaaaacta ccactttaag cgttaagaac
     4081 tgttaagttt agttaagtga ggatagttca caaaatccat tgttaaactt cacgaaagtg
     4141 gtaaaactca aaatgcttta tataggatta cagcatcgct ctttcttcga ttgcgcgttg
     4201 ggtaaaaaat attatgaagt aaaaattgac gatgacacgt tccttacggc tcatcagatg
     4261 aaacagctac aaaaacgaaa tgatcaactc gaagaaaatt taattctaaa aaagcgattg
     4321 ccatattcac gcctcgctcg acgaactatt aaaggtcaag atttacctga agatcatcct
     4381 ttttaggaaa ttgaagcttt ttatgttgca caatgcattt ataatactac aatgatgttt
     4441 tcaccagata ttcttctagg gtgcggtgta atgaaacaga tacacttgca aaagaaaatt
     4501 caccgcgaat ttactaaaat tatgaataat tatgttaatc ttccgaaatt tttttccaaa
     4561 attaagggat caagctggtg ttatagattg tttaaggttg gcaaaaaaat aacttctttt
     4621 taaacaatta tagaaaaccg atactctgtt aagttggttg acacggtgtc gatttttatg
     4681 actttcttat tctgaaactt cactaacgga cagtacctaa aaagtctata gtatggacgt
     4741 ttacgagtac tattttatca aaaatgctgc tcatttcaac ttatatgttt tagtgaacta
     4801 cccccactta
//
LOCUS       DADQCX010000140         4744 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.145, whole genome shotgun sequence.
ACCESSION   DADQCX010000140 DADQCX010000000
VERSION     DADQCX010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.145"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            25..696
                     /locus_tag="J8R83_002617"
     CDS             25..696
                     /locus_tag="J8R83_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9575723.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="J8R83_002618"
     CDS             755..1195
                     /locus_tag="J8R83_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575724.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="J8R83_002619"
     CDS             1207..1875
                     /locus_tag="J8R83_002619"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAZ9575725.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="J8R83_002620"
     CDS             1939..2562
                     /locus_tag="J8R83_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAZ9575726.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="J8R83_002621"
     CDS             2618..3004
                     /locus_tag="J8R83_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAZ9575727.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="J8R83_002622"
     CDS             3217..4608
                     /locus_tag="J8R83_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAZ9575728.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1580 a          782 c         1011 g         1371 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttg
//
LOCUS       DADQCX010000141         4727 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.146, whole genome shotgun sequence.
ACCESSION   DADQCX010000141 DADQCX010000000
VERSION     DADQCX010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.146"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            828..1169
                     /locus_tag="J8R83_002623"
     CDS             828..1169
                     /locus_tag="J8R83_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575729.1"
                     /translation="MSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRKLDQDR
                     WEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLKEQLVN
                     KGKRYGIEVRS"
     gene            1766..2161
                     /locus_tag="J8R83_002624"
                     /pseudo
     CDS             1766..2161
                     /locus_tag="J8R83_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            2239..2751
                     /locus_tag="J8R83_002625"
     CDS             2239..2751
                     /locus_tag="J8R83_002625"
                     /inference="COORDINATES: protein motif:HMM:NF024954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9575730.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTLKKADSKKQQVFLE
                     ETFPSLKKNC"
     gene            3009..4229
                     /locus_tag="J8R83_002626"
                     /pseudo
     CDS             3009..4229
                     /locus_tag="J8R83_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352449.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            4222..4569
                     /locus_tag="J8R83_002627"
     CDS             4222..4569
                     /locus_tag="J8R83_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575731.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
BASE COUNT         1739 a          724 c          968 g         1296 t
ORIGIN      
        1 tgacaaaaaa aatagaagta tatgttgatg gatcacaaga agaaagggat tccttttttg
       61 attttttttg gaaaaatagt agagaatatg taaaagcgtt gaatctggta tataaacagc
      121 taatgtttga agagttgata aaagatgcaa ttaaagaaat ggatcaaggt tatgctgaga
      181 gagaagaaag tattcaaaat cggattgaaa agttagcata tactgatcca atagatcaaa
      241 aaaaacttga taaagcaaaa gctgaattat ctaaattgag aaatgaaaaa aataaagaag
      301 cgagagaaat attaacgcaa gcgatagggt tgaagagtca aacgagaaca cgagatgtag
      361 caaaaaaatt agactttgac tttggagatt ttgttgattc cgcaaatatg aaagctagta
      421 aagattttgg caatgatttt atcggaattg tgaccggaca aagaacgcct agaatatata
      481 aaaatagaaa caaatatgga ttattacctt ttagaggtcg agatattaaa atccataaag
      541 atgataagtt ttatatttat ttacctaaag gctttaggtt taaagtgaat ttaggtagca
      601 agccaagaaa agcaagagat gttgcttcag ttttacaaca cattatggat ggcgattaca
      661 aattaaatca aagtaatctt atttttgatg gaagaaaatt attttttaat ctaacaattt
      721 cttttgaaaa aagctataat gaaatggaat tcaagaaagg taatgaattg atcgtaaact
      781 ttgcagattt gtgtagcggt gaatgtttaa ttaatgataa atctgtaatg tcttttggtg
      841 atagccaata tataagaaac ttcaaaagta aaattttagc aatgaaatca aaagaacaaa
      901 gccgaggagt cttttctaag ggcggtcatg gtcgaaaaag aaaattagat caagatcgat
      961 gggaagcaat aaagaaaaga gaaagtaatt ttgttaaaac ttataataat caatgttctg
     1021 caaaaatcgt taaaactgct attcgcaata aagctcaaat tattcgtatc attgaaccag
     1081 ataaggctta tggcgaatgg gcttactatc aattgaaaga acaactagta aacaaaggaa
     1141 aaagatatgg gatagaagtc agaagttagt aaattaaaca atcgttgatt tggcaacgaa
     1201 atagtgaggg aaaatccact cactgaaggg taaactccgt caagttgtgt gaccagacgg
     1261 aaggacgaat gttgttgagg ttttagaacc atataaaaca gcatgtttct caaattttta
     1321 ggataaggga aattgctagc agtttgtttt agaaccatat aaaacagcat gtttctcaaa
     1381 tgagtacttt aaattaattg atggcgttcc tgctttagaa ccatataaaa caacatggat
     1441 ttaaaacaag aagtaagtca gttctccttt tactttagta aggaaaaata aagtattctc
     1501 aataaaactt aaaataagca aacctttgtt ttaaaatgat tgtcaagtta aaaaaatctg
     1561 ggatcatata aaatagtata gttctcaaat atgattagaa accctattaa agagcaatat
     1621 taagccaact tacttaaatc gtttaattaa gaacaataat ctcttttagt cagactttta
     1681 gtctgacttt tttgtatttc caaaatttat tctttacaaa aacgaacata cgtttgtata
     1741 attacttgtg aatgggggaa taaaaatgtt tgattacagt agagaaccgg tgaatgacta
     1801 ttttttaatc gacatgaagt ctttctatgc tagcgtggaa tgtattgaac gaaatttaga
     1861 cccaatgact acaccgttaa ttgtcatgag tagatcggac aacactggtt caggtctgac
     1921 tctagcttct tcacctactg caaagaaaaa atatcatatt actaatgtta gtagagctac
     1981 tgatttacct tatccattac caaaagaact tcatattgtt ccaccacgaa tgaacttata
     2041 tataaaaaaa aatatggaag ttaatcagat ttttagaaag tatgtcgcag atgaagattt
     2101 attgatttat tcgattgatg aatcaatttt aaaagtgaca aaatccttaa atttatttac
     2161 tatataaatt gagttaaatt gtattcgttt ttcctcctat aggcgtatac taaagaaaac
     2221 acttgaggag tggggaacat ggaaacagaa cgccaaatcc gtgaattgga aaaagcgatg
     2281 aatacgacag acaaccgccg gttgtacgag cgtttcctgg cagtcaagtt ggttcttgaa
     2341 ggccacaccc ggaaagaagc cgggcacacc atcggccgcg acgagcatac tgtcagccac
     2401 tatgtgaaaa actactgcca taatggaatc caaggtttag tctccaaaaa acaaagcgga
     2461 cgaccttcac ggctgacaga tgaacaggaa gcggaactgg tccaaatcgt cgcctaccac
     2521 actccggagg aagtaggttt caaatcccgt gccaattgga cattggcgat tgtgtgtgac
     2581 ctgattctcc gggaatggag ttatggatat acgcaaaaag gcgtggcgga cctccttcac
     2641 cggctaggac taagctggac ccgtccgacg tataccctca aaaaagcgga ttccaagaaa
     2701 caacaggtat ttttggaaga aaccttcccg agcctaaaaa aaaattgctg aatagcgata
     2761 ttgaccacct cctattcgag gacgaaacca tgatccggga ttaccaagcc attggctgca
     2821 cctggtttct ccgcggccac cagcgaaaaa tccccactta tggacaacac aaaggggtaa
     2881 aattgatagg caccttggat tatgaaaccg gtcggatcat ttgtacagaa gaaggggcat
     2941 acgatgcagc ggccttcctc cgttttctgg agcggacgtt gcgggaatac cccaccggaa
     3001 aaatcgtgat ggtattggat aatgccctta tccaccacgc caagctgatc cagtcttttc
     3061 ttgaagaaaa cgctaggcgc ctggcactca tcttcctccc tccctacagc cctcagttga
     3121 acctaatgga aggcgtttgg aagtggctca aggaatcggt catcaacaat gttttttttg
     3181 accacgtcca gaaaatcaaa cagtcggtcc gcggtttctt agccgatgta aacgagcgtc
     3241 cccttgaggt gattgaccga ctgtgcgtgc ggatgtaaag tatttaattc aacctatata
     3301 gttcaggaac aagaagcgag agaagaagag aattagctaa aataatcaaa gatgagattc
     3361 agaaagaaac aggtctaata gcaacagtcg gaataggaga taacccatta ttagctaaac
     3421 ttgcactgga caatgaagcg aagagtagta aagaatttat agctgagtgg acttatgaga
     3481 ctgtacctga aaaaatatgg aaaataaacg agatgactga cttttggggc attggatcac
     3541 gcatgaaaaa aagattgaat catatgggaa ttatgagtat agaagattta gcaaattgga
     3601 atccctacac aattaaaagt cagttaggtg taatcggact ccagttatat ttccatacca
     3661 atggaattga tcgtacggat attgctattc caccagaacc aaccaaagaa aagtcttatg
     3721 ggaattcaca agttctacca aaagattata cgaggagaga agaagtagaa ctagtagtca
     3781 aggagatggc agagcaagta gccattcgaa ttagacaaca caattgcaaa actggttgtg
     3841 tacgcttagc aattggtacg tcaattttgg aagaaaaatc aggtttctcg caccagatga
     3901 aaataccaat tacagataat acgaaagaat tacaaaatta ttgtcttttt ttattcaata
     3961 agttttatga ggggcaggaa gtacgacata taggagtaac ttatagcaga ttagtataca
     4021 cagattccct acaattagat ttatttagtg atccaagaaa aaagattgct gaagaaaatt
     4081 tggataggat tattgataag attagacaaa aatatggatt tacagctatt atacatgctt
     4141 catctatgtt agaaggtgca agaagtatta cgagaagcac tttaatagga ggacacgcag
     4201 gaggattagg aggtttgcat aatgattgaa tataacgata gaggacgttt aaaatggtcg
     4261 ggattttatt tgtctgatca tactgaaaga atcaatgcag acaatgtaca acgtgctaat
     4321 cataatttgg caaaagaaca aatgacgact gaagagattg cgaaaatact gagaactgct
     4381 gtcataaaaa atagacccgt ctgcattcaa aaagaggaac gaaacgctga aggttactat
     4441 ccagatgatg tagtaggaaa aattattgga tatgacgagc ttggtgtatt tgtggaagaa
     4501 gaaaaagttc actatgatga aattaggaat gtttctttct cggaattatt aaaatggagt
     4561 cagatatgaa cattattaaa aaatacgaat tcggttatat tacgtatgaa cagctaatag
     4621 aggaattatg gggatatggt caacaattaa ttaatgaagt ggggattgat tgcttttgtt
     4681 tctatattga atccggagca ggataccata agaacagata ctatata
//
LOCUS       DADQCX010000142         4621 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.147, whole genome shotgun sequence.
ACCESSION   DADQCX010000142 DADQCX010000000
VERSION     DADQCX010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.147"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1136)
                     /locus_tag="J8R83_002628"
     CDS             complement(<1..1136)
                     /locus_tag="J8R83_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAZ9575732.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTK"
     gene            complement(1290..1820)
                     /locus_tag="J8R83_002629"
     CDS             complement(1290..1820)
                     /locus_tag="J8R83_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575733.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(1919..2269)
                     /locus_tag="J8R83_002630"
     CDS             complement(1919..2269)
                     /locus_tag="J8R83_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAZ9575734.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2426..3955)
                     /gene="ahpF"
                     /locus_tag="J8R83_002631"
     CDS             complement(2426..3955)
                     /gene="ahpF"
                     /locus_tag="J8R83_002631"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAZ9575735.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(3965..4528)
                     /gene="ahpC"
                     /locus_tag="J8R83_002632"
     CDS             complement(3965..4528)
                     /gene="ahpC"
                     /locus_tag="J8R83_002632"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAZ9575736.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
BASE COUNT         1547 a          937 c          748 g         1389 t
ORIGIN      
        1 ttttttgtaa aatatttgag aacaagtgga gaaataagtg tacttaataa aatcacgata
       61 actaaaggtg aatagtactg tggttcgatc aattgacttt gctgtccaat ttgtaaaatg
      121 atcaaagcca tttctccacg cgaaatcata ccagcaccga ccatcaatga actatgttga
      181 gaaaaaccgg caatctgagc accaaaataa cctccaagca atttggtcaa aatcgctaca
      241 agcgtcaata tagaaataaa gagtagttgt tcactaaagt cagaaaaatc aacttctaat
      301 cctacactga caaaaaatac tggtataaat actgcatatc ctaaagcctc tacattgtgg
      361 tatacttctt ctttaacctt tgtctgactg acagctatcc cagcaaaaaa agcaccaatg
      421 acagagctaa gcccaacaag atccgctacg taagacattc ctaaacaaat aactagcgat
      481 acgatgataa tagaagaatt tgcgtacact ttttctgcaa atgaaagtag gaaaggcgca
      541 atccatttga ctaataagaa aataaaaaca aaataaatta gctgttcaat caaaacaagc
      601 ggtaaagaag cattgctaga agcttccccc gttagaaaag ataggctgaa acttagaact
      661 aaaacgacta aaatgtcatc taccacagaa gcacccaaaa ttgttgatcc ttcttttgta
      721 ttcactacgt ttagttcttt taatacttct actgaaatac tgacagaagt tgccgcaaga
      781 ataatcccaa agaaaatcgc ttcatttccc gaaacttgga atgctttgcc tgtcaaccag
      841 ccaaaaacaa ccgggaagat gatcccaagc aaagcaacga acataccagg tcggaaatat
      901 tttttcaaaa gagataaatc actttccaga ccagctaaaa acattaataa gatcacacca
      961 atctccgaaa agtcatggac tagaatatca ggtttgaccc aattcaatcc agcttggcct
     1021 agcaaaacac caacaagtaa ttgtccaatc actgctggga tacctaatct ccgcgagata
     1081 tgtgagccaa tcgttgttga aatcaatatc aggcataaaa taccaataaa ttccattctc
     1141 atcattcctt tgtataaaat atagcccgaa cttagcataa catacattat tgaaaaaata
     1201 ggaaaatata ctcacaaaaa aaccaacaat ccaaaagatt tttttggatt gttggttttt
     1261 atacggtcta ttttaataac taaaaatgat taacgtatag tcatttttct tattctgatg
     1321 aaattgataa tctcctggat gcccatgaaa atcaaaataa agccgaatat ttggaataga
     1381 agcatcaaac ttttgaatgg attgaacaat aagacgaatc cgccaatcaa caacagaata
     1441 ctactataaa cactccaact tttagctttt gtattcatgc tgaagaacaa ctggaacaag
     1501 ctgttgatga taacagctaa tccaagaaga atcggcagga tagaaacgat tgcaggtgca
     1561 aaagcataga cgatcagagc taagatcagg aaaaaaagac cactgaacag accgatactc
     1621 caagaacctg ttttcctttt aaaacggtaa gcctcaaaaa gattcaacaa cccaagcaaa
     1681 acaagatagg cggtgatcag ataaccgata aaatgaaaaa cagcagaagg gtttagcaca
     1741 atcgcaatcc cagaaataat ataaacagca gctcttaata aggcgtattt ttgaatattt
     1801 tgtttaatcg tctcaaacat ataagaaaac ctcctttgac ttattttaac gtgaactagt
     1861 cattttacca aattaaatgt tacaaaatga gcgaaggaga agaatatctc tggaaaaatc
     1921 aacttctgag gatcttttcc atttttttgc cttttgctag ctcatcgatc attttatcta
     1981 aataacgaat ttctttcatc aagttatcct cgatgtcttc tactcgtaca ccacaaacaa
     2041 cacctgtaat caaggaacgt gaaggattgg ggacaggggc ttccgcaaaa aattgttcga
     2101 aagtcacttg tttttgtagt tgatattcta gttctgtttg ggaataaccc gtcagccaac
     2161 aaatgatttc atctacttcc tcttttatac gatcttttct ctccgctttt gctacataca
     2221 taggataaac gcttgcaaaa cttgtcgtaa aaatacgatt ttgcgccata atcagtcacc
     2281 tttctttttt tcaaattatt tactacttat agtatataag aaaaagagaa gaaaaagcga
     2341 ttattcaaaa aaacaaaaag gattgtgaca aaattcttgt caccatcctt ttttccgctc
     2401 tctgactttt tacaatcttc atagctcaag tgcgcatcag ataatcgaat gctcctaaag
     2461 ctgcagtagc tcctgaaccc attgaaacaa tgatttgttt gtatggacta tctgtacaat
     2521 caccagctgc gaaaacgccg gggatattcg ttgcgccatt tttctcggtc actatttcat
     2581 ttcttggatt catttcgatc gttccatcta gccaatccgt attagggagt aagccgacta
     2641 gaatgaatac tcctgaaaca gctagtgtat gcatctccat cgtacggcga tcgatatagg
     2701 agagagattc tacctgattc gtaccgctga tttctttcgt cgctgcatgt ttgataacag
     2761 tgacattcgc aagagagact agtttatcct gtaagatttg atctgctttt aattctggta
     2821 agaattctag aacatataca tgttttgcta acccagccaa atcgattgct gcttcaacac
     2881 cagaattacc accaccgata acagcaatct cttttccttt aaataaaggg ccgtcacagt
     2941 gtgggcaata agcaattcct ttatttttaa actctttttc gcctggtaca ttgatagaac
     3001 gccagtgcgc acctgtcgcg atgatggcgg tttttgcttt aagtgatata ccgttagcta
     3061 agccaatatt aataaaatgt tgctctttat ttaaggaaac ggcctgttga ttcatcataa
     3121 tgtcgatagg gtaactacgc acatgacttt ctacttgctg catcaatttt ggaccttctg
     3181 tgtaagaggt accaatcata ttttcaatcc ctagtgtttc aacgacttgt ccgccgaaag
     3241 aatcagcgac aagtcctgta cggattcctt tacgtgctgc atagatagct gcactactag
     3301 ctgctggtcc accgccaatt actaatacat cataaggttc tttttcaaac aactcttctt
     3361 caatcaaagg gccagtgatt ttttcaacaa tttgttcgat cgtcatgcgt ccgctactaa
     3421 attcttctcc atttaaaaac acagttggca ctgccatgat ttttttatca tcgatttctt
     3481 tttggaacat cccaccttca atcatcgtat gagtaatatt tggatttaat acagctaata
     3541 tattcaatgc ctgtacaacg tcggggcaat tatgacaagt caagctaaca taactgtcaa
     3601 aatgcaatgt ttgtgttatt tttttgattt taagactcaa agattcactg attttcggtg
     3661 cccgtccact aatttgtaac atagccagta aaaaagagga aaattcatga ccgaggggga
     3721 taccagcaaa aacgattcca ctttctttgc caactggatt gatagaaaaa ctaggtgtgc
     3781 gcatcgaatc tcttttttcc caagagattt taggagacat ttctgctatt tccttcgtaa
     3841 attcagctag tttttgacta ttttcactat tatccaaact aacagaaaaa acaataggag
     3901 attcaatcag tgctaaatat tgttcgagat tttgtttagt ttctttgtct aacatatcca
     3961 ccacctaaat ctttccaaca agatcaaaac ttggtttcaa tgtttcgcca ctttctttcc
     4021 attttgccgg acaaacttca cctgggtggg tacgtacata ttgagcagcg cgaatcttat
     4081 caatcagtgc actagcgtca cgaccgattc catctgcatt gatttccata gcttgaacga
     4141 ttccgtctgg atcaataata aatgttcctc gctgagctaa tccttgctct tcatccaaaa
     4201 catcaaaaat acgagaaatc tgatgagacg gatcaccgat catcacgtat tcgattttac
     4261 cgatagcatc tgatgtatca tgccatgctt tgtgagtaaa gtgggtatcg gtagagcaag
     4321 aaaagacttc aacacctaaa gatttcaatg tactgtattg ttcttgtaag tcttctaatt
     4381 cagtaggaca aacaaaagta aaatcagctg gatagaagca aagaatactc cagttcccca
     4441 taagatcttt ttcactgact tctaaaaatt ctccttgatg ataagcatgt gcattaaatt
     4501 cttcgatttt tttcccaatc aatgacatag taaaacctcc aataataatt atttatttat
     4561 aattattgta atttagttgg agttgcaaag tcaatggata ttttgttatt taataaagat
     4621 t
//
LOCUS       DADQCX010000143         4606 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.148, whole genome shotgun sequence.
ACCESSION   DADQCX010000143 DADQCX010000000
VERSION     DADQCX010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.148"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            314..595
                     /locus_tag="J8R83_002633"
                     /pseudo
     CDS             314..595
                     /locus_tag="J8R83_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            669..1349
                     /locus_tag="J8R83_002634"
     CDS             669..1349
                     /locus_tag="J8R83_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAZ9575737.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVSH
                     ATIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
     gene            2075..2170
                     /locus_tag="J8R83_002635"
     CDS             2075..2170
                     /locus_tag="J8R83_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAZ9575738.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2472..2717)
                     /locus_tag="J8R83_002636"
     CDS             complement(2472..2717)
                     /locus_tag="J8R83_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575739.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            3062..3346
                     /locus_tag="J8R83_002637"
     CDS             3062..3346
                     /locus_tag="J8R83_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575740.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            3349..3765
                     /locus_tag="J8R83_002638"
     CDS             3349..3765
                     /locus_tag="J8R83_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575741.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(3902..4579)
                     /locus_tag="J8R83_002639"
     CDS             complement(3902..4579)
                     /locus_tag="J8R83_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9575742.1"
                     /translation="MNLVPLKNFNAKQMDLFFALCARMKDRGLKKVRFSFEELKELSD
                     YKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEINKTKKFVEVSVNPD
                     LEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIEEFRSLMDIP
                     EYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKIS
                     LRNWLEE"
BASE COUNT         1566 a          810 c          759 g         1471 t
ORIGIN      
        1 ctagactgtg caaaatagag acacttgaaa aatctatcgg gggtcagaaa cttaaaagtt
       61 tttgatcctt tattttcaag tctgatttgg cagcttttcg gcagctcatt tatttatggt
      121 cagaaataga tgctgaaatt ttaatctatt agcaaatagt ccagaacgta tgaagaggag
      181 tcggatatca tttgtcatta acaccataaa tatttataaa attcgtgttc acctacaatt
      241 aaatttaata tataatattc gttgtaaggg cttataattt tttgttaatg aacaagatag
      301 gaagaaacat ttaatggaca gttttcagag attgtcacta gtaaatcaat ttgagttatt
      361 ggctaaattt gaggaccaaa acagatctta ttatgaaaga aaaatcgaaa tattgagaga
      421 aggttacgag tatcattatg atgatgaaat ttggagtgat ctttctgagc catttccgaa
      481 agaagattct cgatttgtat tagatgtatt gaacatgtat cgagatatca attttagtaa
      541 atcaaagcta aacttagatg aaaaccaaat tactaattca tactatactc atttcggttc
      601 tgttgcaaag ttttccaaaa aatctatttt agtgtaaaat tgagaaaaaa gacagagagg
      661 gcagagtaat gaatcatttt aaaggcaaac aattcaaaaa agacgtcatt attgtcgctg
      721 ttggttacta cctgcgttac aatctaagct atcgtgaagt tcaggaattg ttatatgatc
      781 gtggcattaa cgtttctcat gcgacgattt atcgttgggt gcaagaatat ggcaaactac
      841 tctatcaaat ttggaaaaag aaaaataaaa aatcctttta ttcatggaaa atggatgaaa
      901 cgtacatcaa aattaaagga aaatggcatt atttgtatcg agccatcgat gcagatggtt
      961 taaccttgga tatttggtta cgtaaaaaac gggacacaca agcagcctat gcttttctta
     1021 agcggttagt gaagcagttt gatgaaccga aggttgtagt cacagataaa gccccctcta
     1081 ttacaagtgc ctttaagaaa ctaaaagaat acggctttta tcaagggaca gaacatcgta
     1141 ccattaaata cctgaataat ttgattgaac aagaccatcg tccagtaaag agacgcaata
     1201 aattctatcg aagtttacgc actgcctcta ccacgattaa aggcatggaa gccattcgag
     1261 gattatataa gaaaacccga aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa
     1321 tcaaggtatt attgggaatc ccagcttaaa tcatagatac cgtaagggat tttattcttt
     1381 atttaaaact ttgcaacaga accattccgt tttttcatcc attcctttct tcccccctta
     1441 caaataaata ataaccttta acaaccaact cgtaaatagg ttggttgtta ttatacaaaa
     1501 ggatattagt actcagataa aaagttgtta gtactcagat aaaaagttgt tagtactcag
     1561 ataaaaagtt gttagtactc agataaaaag ttgttagtac ccttctgtat ccgttgggag
     1621 agtaaggctc aactgccccc taaaaagggt tctaaaaaat ctttaaaaaa taaataaaat
     1681 aaacgcgcgc gcgcgagcaa aatttcccgc caaaaaatca cccacttttt aaaataaaca
     1741 ggttcgcgca tgatattaaa ctgccaatct agctccctat ggtcgctgta agaaggagtg
     1801 atcgctacgc tctcacattt tacttgcagc agtcgccttt aggctccttc gccaaaaata
     1861 attcattagg gactcctttg tggcgtcctg agagctcgtc taagccgttc taagacaaga
     1921 ttcgataaaa actatgtcct tcgttctaaa gcgccttaca ggcggtcagg gcaagcccta
     1981 acaaccccaa ggcaataaaa aacttaggct tatttttgct tttttattgt ataattgatt
     2041 gtcgcctatc cgacagtctt gcgactggaa ggaggtgtgt ttcgtgttca ctaactttat
     2101 ttgctccctt cttgttgggc ttttaagcgc tttgttcagt tactggttga ataaccgaaa
     2161 caagaagtaa aacttaatta aggcgactca gcccacaaaa aaagccccag agaatccgac
     2221 ctctctgggg ctttcgtgtg tttcgtgttc acttatttgc aatcaaatta taacagaaat
     2281 aaatatttat ttcaaaaata tcctacaaaa gtctaaaatc cgtaattatt tcttatatgc
     2341 aacatttaca aataaagtcg ctctgagagc tcgtattttt cgatttaaga cgttttattt
     2401 agtttttggt gtatttcatt ggtccaagct aaaaaactct tagaagcgat tttagagcca
     2461 tttaaaccca cttaattata ttctccatga aattcgctcc atgcgtcaaa agctgcgtct
     2521 gaaattccgc cgtcttcgtt cactagttgc attaattttt ccaacgatcg ttttctttcg
     2581 ggtgtcatat ttttatattc caacaatttt tcgtctgtta aatcgaactt gattgcttga
     2641 attgcttgct ctaatttttc taagttttga aaatattcgt aaggaaattt ttccattttt
     2701 tctttctcca gtctcacaat ttttctagaa ataaaatcac ttctttgccg tctatactct
     2761 caaaaaaaat gtcgtttgaa aaactaaata aatttttgat cgtgcatttt taaatttggt
     2821 tatcgattac acgtgcagca ctcccccccg aattttaaag agcataagga aacgtgtacc
     2881 cactttctaa aaaaagtggg tagataggct gtgcctatca cgtttctcag aaaaaaattt
     2941 gatatcactt tttcgccatc gtgggtagct tatgtatagc attttggcaa aaaacagcta
     3001 tacaaatata gtatttgtat ggtatacata aattatacat aattgcaaaa ggagattttt
     3061 tatggacatt ttagttcgga atattgatcc aaagtttgtt gcaacaatag acaaacgttg
     3121 ccaagaactc acgaataaaa caggagaaaa atggagtcga aataaatatc taaaagtttt
     3181 aatcgaaagt gattttgacc gtcaacttac gacttacaaa aaagaccaat tcgatttatt
     3241 gctcgataaa tttattgcta tccaaacaga aaatactcaa atattaagcg agtatgtcta
     3301 cacaaataat caaatcattg aaatgcttat cggaggaatg atataaccat gagaaaaact
     3361 tctgtccaaa aacatgttac tttgtaccct agtcatgttg acgttttaga ttccatcatc
     3421 gaaaaaaatc cagatatcaa taactactcg gaagccattc gctttttatg tatgagttat
     3481 gaacccgata ccaacacgac cactaccagc aatcaggcaa aactaaatgc tatgggaaaa
     3541 gaaatttcca tcatgactga aatcatcgca gaatttgctg atttatatct aaaagataca
     3601 ggcgttctta ttggcacaaa ttctaaagta tatcaagaag tgaaagaaaa aatcgaagct
     3661 aaactaaatc catcaaatcg aaatcgacca aagaatcatc aaaaagaaac cagtcaaaca
     3721 gtcacttcta gaaatttcga cccaacaaat tttctaaaac gataaaaaac agataggagt
     3781 tattcctatc tgttttttat ttagaagccc catacaatat gctagaatgt actagcaatc
     3841 ttagtcggtt gtaagggact tgtctacttg cttaatgtaa ggggggcgag ttctttttta
     3901 tttattcttc taaccagtta cgcagagaaa tctttggcaa atctgacgtt aggcttgaaa
     3961 aagtaaattc taatttggcg attttattgc ccttttttgc ttttattttt gtgactttaa
     4021 gatcattgaa gtattttttt agttctcgta atgcaggatt taatactttt tgatcaatgt
     4081 tacccatttg atagtattct gggatatcca ttaagctcct aaactcttca atacgaacta
     4141 cataataacc agtagaacgg tactgcataa gcagtcggaa tagagttttt gcatacgtag
     4201 aacgcaacga cgtgaaagca gataattcaa atctactaaa ttcagctgtt aaaccattaa
     4261 taatatattc taggtccgga ttaacactga cttcaacaaa cttttttgtt ttattgattt
     4321 caaaaccagt aaacaaaaca aagtagcgaa tagaatcctc atcttcagta cggtaagtaa
     4381 gattaagcat atctttatag agcttttcta aatcaccgac aaaggctttt gtagcagtca
     4441 tcttataatc acttaactct tttaattcct cgaaagaaaa tctaactttt ttcaaaccac
     4501 gatctttcat acgagcgcat aatgcaaaaa ataaatccat ctgcttagca ttgaaatttt
     4561 tcagcggtac taaattcaat tcattttgat atttgactgt taattc
//
LOCUS       DADQCX010000144         4594 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.149, whole genome shotgun sequence.
ACCESSION   DADQCX010000144 DADQCX010000000
VERSION     DADQCX010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.149"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            56..286
                     /locus_tag="J8R83_002640"
     CDS             56..286
                     /locus_tag="J8R83_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAZ9575743.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            383..1684
                     /gene="murA"
                     /locus_tag="J8R83_002641"
     CDS             383..1684
                     /gene="murA"
                     /locus_tag="J8R83_002641"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAZ9575744.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1697..1873
                     /locus_tag="J8R83_002642"
     CDS             1697..1873
                     /locus_tag="J8R83_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAZ9575745.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2008..2304
                     /gene="yidD"
                     /locus_tag="J8R83_002643"
     CDS             2008..2304
                     /gene="yidD"
                     /locus_tag="J8R83_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAZ9575746.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2489..2956
                     /locus_tag="J8R83_002644"
     CDS             2489..2956
                     /locus_tag="J8R83_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575747.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3041..3925
                     /locus_tag="J8R83_002645"
     CDS             3041..3925
                     /locus_tag="J8R83_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9575748.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4042..4275
                     /locus_tag="J8R83_002646"
     CDS             4042..4275
                     /locus_tag="J8R83_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAZ9575749.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4363..4443
                     /locus_tag="J8R83_002647"
     tRNA            4363..4443
                     /locus_tag="J8R83_002647"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4397..4399,aa:Tyr,seq:gta)
     gene            4450..4521
                     /locus_tag="J8R83_002648"
     tRNA            4450..4521
                     /locus_tag="J8R83_002648"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4482..4484,aa:Gln,seq:ttg)
BASE COUNT         1552 a          721 c         1015 g         1306 t
ORIGIN      
        1 atggtattat cattttatta gttattataa aacaatcgtt agaaaggacg tcattatgca
       61 agtatacgga attgatgcgg tgcttcgaat cgtgagtcat ttggcgttta tctacttagc
      121 cttctggtct ttacgttcgt tacgcattga aacttttttc agaccaatgc ataatacgca
      181 aattagaatg gcaatcgtac ttttttcaat ttttttaggg tacactgcaa gtaatttttt
      241 cttagaagtt atcgctttat gccgaaatct tttcgttagc ctgtaaattt taaaaaaagg
      301 tactatttta aaagcaagga tgttataata gaaaagattt tgagtaagtg tatgctcatt
      361 ggaatttttt ggagggaaca acatggaaga gatcatcgta agaggtggca atcaattaaa
      421 tggaacagta agaattgaag gagctaaaaa tgctgttttg cctattttag ctgctagttt
      481 gttagcagaa gaaggtatta cgacattaga caacgttccg attctttctg atgtcttcac
      541 tatgaatcaa gtgattcgtc acttaaacgt agatgtagat tttgatgaac aaaagaatca
      601 agtaacaatc gacgcttcaa gacaattaga aatcgaagcg ccttatgagt atgttagtca
      661 aatgcgtgct tcaatcgttg tgatgggtcc gctacttgcc agaaatggac atgcaaaagt
      721 agctatgcct ggtggatgtg cgattggtaa acgaccaatc gatttgcatt taaaaggatt
      781 tcaagcttta ggagcaaaaa ttattcaaaa aaacggctat atcgaagcaa ttgcggatga
      841 attgatcggt aacacgattt atttagattt ccctagtgta ggtgctactc aaaatatcat
      901 gatggctgcc gtaaaagcaa aaggaacaac catcattgaa aacgtagctc gcgaaccaga
      961 aatcgttgat ttagcaaaca ttttgaataa aatgggcgct caagtctatg gagctggtac
     1021 tgaaacaatg cgtattgaag gcgtggatca tttacatgca gtcaaccact caatcgtaca
     1081 agatcgtatc gaagcaggta cctttatggt tgctgctgca atgacacaag gcaatgtgct
     1141 gattgcagat gctatctctg aacataaccg cccattgatt tctaaattga tcgaaatggg
     1201 tgcagaaatc attgaagaag aaggcggagt ccgtgtcatc ggaccaaaac atatcttacc
     1261 tacagatgta aaaacgatgc ctcatcctgg tttccctaca gatatgcaag ctcaaatgac
     1321 agctatccaa ttagttgcag aaggtacaag tgtagtgact gaaacagtgt ttgaaaatcg
     1381 tttccaacat ttagaagaga tgcgccgtat gaacgctcat gtcaaaatcg acggaaatgt
     1441 agcaatcatg gatggaaacc atgaattgca aggtgcagaa gtatatgcaa cagacttgcg
     1501 ggcagcagca gcattagttt tagctggctt gaaagcaaat ggaatcacac gtgtgcgtaa
     1561 cttgaattat ctagaccgtg gatattataa tttccatatc aaactacagc aattaggtgc
     1621 agacgttgaa cgtgtagaca tggatcaaac ttctgctgaa aaaacagcac aaacgattgc
     1681 ttaaggaagt ggctgaatga gtaaccaacg atatatctta ttaactttga taaagatttt
     1741 aatggtgatc ttattgctta tccttctttt tgtggccgga acgatgatcg gatatggtgt
     1801 catcggtggc ggcaatccat ttaaagtatt tcagccaagt ttgtggattc atattcgaga
     1861 cttttttcat tgataaataa gaatcacagt ggttctagtc gatatgaagt gagccatgaa
     1921 gcagaacatg ataaaagaaa acagaaggga acgttgacgt tagtcgcgat cccttttttt
     1981 agtaaaagaa aagaaggaat ctaattgatg aagaagatat tgatttattt agttagagga
     2041 tatcagcgct ttatttcgcc tgcatttcca cctagctgcc gttattaccc aacctgttcc
     2101 aattatatga taaaagcaat tcaaacccat ggcgcgctaa aagggacggt aatggggact
     2161 gcacggatct tacgctgtca tccttttgtc aaaggcggta tcgattatgt accattgaca
     2221 ttccgattaa cgcgaaataa gaaagataaa aaagaaccag attataaaaa ggttgtgaaa
     2281 aatacgggta gcactgagcg ataaagaaac aatttggaaa atagcttctt atattttgca
     2341 aaattgtgag ttattgccga agtgttggat tttgaacacc gtcaaaaaaa aggttgtgaa
     2401 aaatacggct agcactgagc gataaagaaa aagaggaaat ttattgtcaa agtaacaact
     2461 ccgcaactac ttatatgggg gacaaaaaat gatcgaagaa ctaaacaaga aagatttacc
     2521 atggtccttg ttattagatg cagatcctga taaagaaaaa gttcaagtat atgtttccag
     2581 agggagtggc tggatatgga aagaaaaaga aaaaacaata ggtgtactga tctatgtggc
     2641 aagggaaaaa gaatacgaaa tcgtcaatgt agcagtaacc ccaacgtatc aaggaaaggg
     2701 gattggcgga aaattacttg agacagcttt tcagaagctt tcacaactcg cttccagtca
     2761 aactcagatc atcatacgaa ccggcagtac tagcagtgcg gcgttacatc tctatcaaaa
     2821 aatgggctat gtggagattg gtcgagtcaa agactatttt atccatcatt actctgagcc
     2881 catttttgaa aatggagatc aattaaggga tcaagtgatt ttagcaattc acttacctaa
     2941 aaatagcttt aactaataaa atttcaattc aagaaaatgc tttcaaatgc taaatagata
     3001 cattacaata gctttagcaa acaaaaagga gaatattttt atgggaatat tagtttttga
     3061 ttttggtgga tcggctgtca aatatggttg ttgggatggc aaagagatta aaggtaaggg
     3121 acaatttgca acgcctgaat cttgggaaga aatgaaagcg caattatttc aagtttataa
     3181 aaaaatactc gtttcttttg aagtcgaagg aattggaatc agctctcctg gagtagtgaa
     3241 taatgagaaa caggtgattg agggaatcag tgcgattcct tatattcatg gatttaatat
     3301 tttccgagat ttggaaactc tgtttcaact tccagtaacg attgaaaatg acgccaactg
     3361 tgccggaatg gctgaatttt atgaaggtgc tgcccgcgat tatcaagatg ttgcttttgt
     3421 tgtggcagga actgggattg gcggggcgtt gttcacgaaa ggacaaatca ataaaggggc
     3481 acatctttac ggtggagaat ttgggttgat gttcttaaat ggcgataaga cattcagtaa
     3541 acttggtaca gcggtacaga tggcttggcg ttattgtgaa cgcaaaggtc tcgataaaaa
     3601 tgcttatacc ggaaaagatg tctttgaatt agcagaaact ggagatgcaa tagcaaaaga
     3661 agaagttgag agtttttata cgtatcttac aaagggatta ttcagtattc aattttcgtt
     3721 tgatccagaa gtgatcgtat taggcggcgg ggtttctgca aaagaagggc tcattgatga
     3781 gatcaaaagc cgaatgaaga agctgacaga acaattcgat ctgcatgatt tcgaaccgca
     3841 gattttatta tgtgaataca gaaacgatgc taatcttgta ggtgcagcag caaactatct
     3901 cgctgtacgt caaggggaga attaagagct ttagagaagg tgcagcttgc ataaaagaag
     3961 tgaatgaaat gaataggaga tttttaccta aggaatgttt tatttgctgc agtatgataa
     4021 aatatctgag aggtgaaaat gatgtcaaaa aaaaataaag atattgaagt gcgtatagaa
     4081 gaagtgaaaa aagatatcaa aggtaagaat tatgaagtca ctcagttatt tatagggaaa
     4141 aaaatgattg gtgagatctt agcctatgga ccaaaagaat atgaaatttt ctttggtgaa
     4201 gaagattttg gaaaagaaaa aagtcttgaa aatgcgatag aaacagtgat tcgacactgg
     4261 aatctgcacg aataaaaaaa tatcaaaaaa actttcaata aagggttgca aaaatctgga
     4321 aaattaggta ttataactaa gtcaggttga tacaaacctt tcggaggagt agcgaagtgg
     4381 ctaaacgcga cggactgtaa atccgttcct tagggttcag tggttcgaat ccactctcct
     4441 ccatttcatt ggggtatagc caagcggtaa ggcaagggac tttgactccc tcatgcgttg
     4501 gttcgaatcc agctacccca gtataccaca atcgtaagct ctcgttagtt cgagagctct
     4561 tttttttgct ttgctacctt gttccttgaa gatt
//
LOCUS       DADQCX010000145         4496 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.150, whole genome shotgun sequence.
ACCESSION   DADQCX010000145 DADQCX010000000
VERSION     DADQCX010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.150"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..587)
                     /locus_tag="J8R83_002649"
     CDS             complement(<1..587)
                     /locus_tag="J8R83_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575750.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVF"
     gene            complement(735..1277)
                     /locus_tag="J8R83_002650"
     CDS             complement(735..1277)
                     /locus_tag="J8R83_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAZ9575751.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1412..1801
                     /locus_tag="J8R83_002651"
     CDS             1412..1801
                     /locus_tag="J8R83_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575752.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1805..2569
                     /locus_tag="J8R83_002652"
     CDS             1805..2569
                     /locus_tag="J8R83_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9575753.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2698..3645
                     /locus_tag="J8R83_002653"
     CDS             2698..3645
                     /locus_tag="J8R83_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9575754.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3775..>4496
                     /locus_tag="J8R83_002654"
     CDS             3775..>4496
                     /locus_tag="J8R83_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575755.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLG"
BASE COUNT         1565 a          749 c          909 g         1273 t
ORIGIN      
        1 ataaatacac ctagactgac gatgaagagc atatccaaca gatttcctgc gacttggatc
       61 gtcgaagggt tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa gctgtaaata
      121 aaacaggtga caggaactaa tcgaaagaag agcggacatt tcaattggct aaaaatgagt
      181 gaaaaaataa aataagtaaa aatggataaa atcacgacta aaccattcat gataaagaag
      241 aaaagcgtat tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa cgttttaaat
      301 gcaatcaata cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa aaaataggca
      361 ccgaaataaa cagaaaacag taagccgcaa agagaagaca aaatcaaaaa aaacggattt
      421 tcttcggctt ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc actagaaggc
      481 gcatgtgagg tcttaaggta tgaataacat agaaaaaata agatcgtcaa agttgcaaaa
      541 aaagagccta aatgtaaaaa attagtggtt ctacgttgaa tttccataat atctccaaat
      601 taaattgata agtatataaa gtataataac aaattgatga gtatatgtcg atgtttttta
      661 atcaaaataa taaataaaaa ctgtctaaca tttaaaattt aatttagata ttagacagtt
      721 tttaagtttg tgagttattt tccttgtcgt tttctcactt ttttagtcca gaaaccacct
      781 gaaatatatt ttggctcata agaaatgata aaagcacgct cttcgatttc tttgatcagg
      841 cgatacagtt cacgttcgct ttttctagga gaaagtattt cgagaactag ccgctcacct
      901 tccagcccca ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag tatacccggc
      961 aaacttttat cttctgcgct atttgctggc aaaatcgttg tgaccatgat gtatcctaat
     1021 gccaatttgt cttcaatcaa aattccgaca ctgataccta ctgcgtaacc taacgcatag
     1081 acaaataaat tcagtggatt atctaaacga tctaaaacaa gggataagcc gacgatataa
     1141 atcgtgatct cgaccatact gacaagtgga gcaatcagtc gatagccttt cattgtcaac
     1201 atgaaacgta acgtgttcag agtgatataa gcaaaattaa tgaggaagat catccccaac
     1261 atttttggat caatcatttg taaaactcct ttcatttata taacaacaat atcaaaaaaa
     1321 atcgtaagtg aagaaaaatt gaaactttat acatacaaaa aaatgataaa atgattataa
     1381 tagaattata aagataggtt aggtgattaa aatgaaaacg gtcaatcgtg tgttttgtgc
     1441 cagccacgtg ctaagtctcc ttctcagtat atacttaggt gtctattcga ttcaacagcc
     1501 aattgaggta gagaacattg tttttcagat gtcgctgaca gatggtttaa ttttaagcgt
     1561 ttttttcttt ttgatactgt ttattggtaa tattttcggt agcgttgcca gttttttgaa
     1621 tttttctatt tatccactcc tttcgctagc attaggagtg gtgggacttt gttctctgtg
     1681 cttatttccc gagccattca gtcctgcatt tatattattt ggtacactga acctgttcca
     1741 gacaactgtt ggagcatggt tgctatggcg atcaggaaat ttaatgaaaa taggtgagta
     1801 acaattgaat ccaattatat tgaaacgttc tgtccatcat attccagtgt tagaagttgt
     1861 tctgaaagaa ttaagagagg aacgtattcc cgttgtcatc tattatcacg gatggcagac
     1921 aagtaaggag ttagttttga cgcaaggaag aaaaattgcg cagcagggca ttcgtgtgat
     1981 cctgccagat gcgatgaatc atggggagcg caaacagccg gtttcttcta ttccatccta
     2041 tacattttgg gatagtatct acggaaatct gtttgaattt gacacactta tcaagcattt
     2101 agaaaaaaga ggtcttctac atgatcagct tgcagttggc ggggtttcga tggggggaat
     2161 gacaacatgc gccttgttgg ctaaacatcc tcatatagta gcgggcgtgt gtttgatggg
     2221 ttcccctgca cctttggaat atggaaaaga aatcgtaagg cgcgcatcgg aatataatta
     2281 tgtcgtacca aaagactatt ttgatttgat ttcatgggtt aagagctatg atttgtcatt
     2341 gcagccggaa aagttagctg gacgtcctct gttcttttgg catggacaag ctgacgaaaa
     2401 aatcccttat atacaaacgg aacgatttgt agaaaaaaat cggcataagt cttacggaaa
     2461 agaaattgtt tttcgttcct caaaaacaca gcgacatatg gtacaaatac cactaatgga
     2521 agaagcttcc acttttttag caaaaaattt gataaaaaag tataaataat tgaaacggaa
     2581 aatcactcat gacgatagag gattttccgt tttttatttt gggctataat aaactctgtt
     2641 aggaaaattt ggtataattg atagtaagaa tgacaacatg ttagaaagga agagagcatg
     2701 cccactttag cagatgttgc aaaacgtgcc aatgtttcaa aaatgacggt ctctcgagtc
     2761 atcaatcatc cggaacaggt gactgacgaa ttgaaagagt tagttttctc agcaatggct
     2821 gaactggatt accgtccaaa tattgctgca aaagcacttg tcacgaatcg gtcgcagatc
     2881 atcaaattat ttatactgga agaaatcgac acaactgagc cctattacat gaatttgctg
     2941 atgggaatcg ctaaacggat cggtaaagcg cattattctc tccaattagt tacaaatgat
     3001 gccttcgacg tcggttcttg tgatggatac atcatcacag gtgtcagaaa aaaagacttc
     3061 gattggatcg accgtttgga aaaaccagtt gtcttgtttg gggaaaattc tgaaggatat
     3121 gattatgtag acagcgataa tgaatatggt acagcaaaag caacgcaata tgccttagaa
     3181 agagattatc aaacgattat ttatatcggt atcgaagtgg acgagccttt tgaaatttca
     3241 agggaaactg gttatttatc tgtgatgaag gaagttgatc ttcctagtaa aatcttgcgg
     3301 tttccaaatc attcgacaga agtagaaaga tatatgacag aaaactgggc agattttaca
     3361 gataaaactt gttttgtatg tagttcagat cggctagcac taggagcagt aagagggatt
     3421 ataaatgctg gaggacactt gcccgaagaa tttggtgtga ttggatttga tggggtattt
     3481 ttagaccaaa tcagttcacc taaattgaca acgatcaagc aagatattat acgtatgggt
     3541 gaagtatgtg gagaaatgtt gttaaaaaaa atagaagaaa aaggggcgag tcaaggttat
     3601 cgtcgttttt ttcctgaact agttatcaga gagacaacga attaagtctt attactatat
     3661 atatatttat gaaattcatc gctattttct taaaataatc agcgcattgc tactgaaaac
     3721 aatgaatctg tgctattatt gagaaaagtt ccatttttga gaaggatggt ttgaatgaaa
     3781 gaaatcagac gaaaacattt ccgttttcct gcgtacgatg atgagttagg cgtaaaatta
     3841 accaacgaca agaagcgagt attatttgac ggacaagaag atcttttgac tgaacagaat
     3901 cagtccccgt ttgaacagat gaaagaattt catttcacga acacgaacac cgagaaaatc
     3961 cgtcgcaagc gtcgtgcaac aaatggattg aagtcagctc cgcgtaagga aaatttggaa
     4021 aagcataaag gaaaattacc ggattatacc ggccattacc aatcagaaat cacatcgaca
     4081 ggacgaaaaa aactttttgg tgattcctct cgttctgtca gacaaagtga aacaaggaca
     4141 gagtccaagc atactacacg aaacgcatct gttgacacga aggtgcggga gcgttcttat
     4201 tttgttccta aatatgtacc cgcatcgatt atcccagacc ctagagaaag caaaatttct
     4261 gaggatcatt taatcgaatc gatgaaaaaa acggatgact cttatctgtt gttcgataca
     4321 gaaccgacgc cgtatcaaga aaaaagaaat ggtgagccgt ctgtacgaac attcaatcga
     4381 acaaaaacgt tagaggaaac aaagcagtca gaagaaaaaa aatcgaaaaa aagccatggt
     4441 atcttagaac gctcattaca aggattgatc gatgatcaag gaaactcttt gggaga
//
LOCUS       DADQCX010000146         4493 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.151, whole genome shotgun sequence.
ACCESSION   DADQCX010000146 DADQCX010000000
VERSION     DADQCX010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.151"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(239..619)
                     /locus_tag="J8R83_002655"
     CDS             complement(239..619)
                     /locus_tag="J8R83_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAZ9575756.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            701..1876
                     /locus_tag="J8R83_002656"
     CDS             701..1876
                     /locus_tag="J8R83_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9575757.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(1953..2537)
                     /locus_tag="J8R83_002657"
     CDS             complement(1953..2537)
                     /locus_tag="J8R83_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9575758.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            2738..3736
                     /locus_tag="J8R83_002658"
     CDS             2738..3736
                     /locus_tag="J8R83_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9575759.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            3848..4357
                     /locus_tag="J8R83_002659"
     CDS             3848..4357
                     /locus_tag="J8R83_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAZ9575760.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPSILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4387..>4493)
                     /locus_tag="J8R83_002660"
     CDS             complement(4387..>4493)
                     /locus_tag="J8R83_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAZ9575761.1"
                     /translation="HSFILFFVLLELFFAVFLFLGKNSLKQTKKKELV"
BASE COUNT         1437 a          838 c          804 g         1414 t
ORIGIN      
        1 aactatttct tttaagaaat taagtatatt cgctaaacca gtctttcctt cagaaagttc
       61 cgctaacgca aattccaact tgtcatcaat tgaatggacc aaaaattttt tagtaccatc
      121 ctccaaatgc aacataattg taccagcaac tcttttgctt gccaaaattt ccacctcgat
      181 caacttgttc tatggcttac ataaaaattc tagcacattt tcagaaaaaa tacacttttt
      241 atttcttatt ttctttccgt tctagttcag ataatgcttc ttctatccaa ataggtaact
      301 gctccgcaat agtggtaaat ccgatcttac gatttttatt cgtgaaatac ctttttctgc
      361 gatatggaac agctggattt gttttttcta acgttcttaa agataaactg atttttttgg
      421 aatattcatc aatgtcgatg atctgaactg ttactggctg tccgactttt aacaatgaat
      481 ggatattttt cgtataaccg gattgtactt ctgaaacatg aataagtcct tgcgtctcgt
      541 tatcaagaga aacgaatgcg ccataaggct gtatccctgt cacttttcct tcaattattt
      601 gtccaatttt ataagtcatc tacttccctc tcttcgcatt tatcattata ctgtaaatag
      661 ctcaaaaaaa gaagcgacga aaatgactgg aggtcttaag atgatcgaat ttgataaaca
      721 gatttcaaga aaagatacag aaagtgtaaa atgggacgca attgctgaga catatcaaat
      781 ggatgactta cttcctttgt gggtagcaga tatggacttc ttgtctcccg gtggggtagc
      841 taaagcgttt agtgaataca tcaaacatgg aatctttggt tatgccactc tgtctgataa
      901 actatatcag gctatcattc attgggaacg ccaacaccat gctgtggagt tgacgaaaga
      961 aaatatcgtt tttacaagtg gtgtgttaac cagtttagct gcagcagtac aaacttttac
     1021 aaaaccaggc gattctattt tgattcatga cccagtttat cctccatttt cctctattat
     1081 agaaacaaat caacgtcaca tcgttcgaag ctctttgcta gaaaaaaata atcatttcat
     1141 catggacttg tctgacatgg agaaaaaaat cgaagaaaac aatgtaaaag caatgatttt
     1201 atgcaatcct cacaatcctg gagggcgtgt ttggagcaaa gaagaattga aacagttaag
     1261 cgaattgtgt ttaaaacatc aagtgattct gtttagtgac gagatccatc aagatttaac
     1321 tttattcgat catacattta cttccatgct aacgattgat cctaatttag atgatctact
     1381 agttgctttt acttccgcaa ccaagacttt caatctagct gcaatcaaaa attcaatggt
     1441 atttatcaaa aatccagaga tgaaagctga ttttgaaaaa catttagtga tgaaccaaca
     1501 gcacgaaatc aacacttttg gactgattgg aacccaagcg gcttatgaga cgggtggaga
     1561 atggttaagc caactgattc cttatctaga aaaaaatgtt caaacagtta atcagttttt
     1621 tgaacagtat cttccgaaag tgagaataat gaaccctgaa ggaacttact taatgtggtt
     1681 agattttacc gcctatattt cagacgacca agaattggag aacactcttg ttcggaaagg
     1741 aaaagtcgta ttaaatcctg gcatcacgtt tggtccttcc ggtcatgggc atatgcgctt
     1801 gaatattgct tgtccagaag aaactttact ggaaggactt aatcgaatca agtatgcttt
     1861 agagacaatc gattaaatca tttattcaaa ataaaaggac gagaccttac taggtttcgt
     1921 cctttttcat aattactccg taccatacca aactattctg aaatttcaat tgtttcaatc
     1981 actacatcat gtacaggtcg gtcttgtgga ccacgttgta catttgcgat ttcatctact
     2041 gtgtccatcc cttctagtac atgtccaaag actgtatgtc ggaaatctag ccaaggagtt
     2101 ccgccacctt tatacgcttc aatgatttct gatgggaatc cagcaccttc tagttgtcca
     2161 agcatattag ctggcacatt tgtgttattt acaataaaga attggcttcc gtttgtgttt
     2221 ggacctgaat ttgccataga taaagctccg cgaaggttga acagttcacg actgaattca
     2281 tcttcaaaac tttcgccata aatactttcg ccacccattc ctgttccagt tggatcgccg
     2341 ccttggatca tgaaatcagg aataacgcgg tgaaaaatca cgccatcata ataacctttt
     2401 ttggaaagtt caatgaaatt ttgaaccgtc ttcggtgcta gttcagggaa taattgaaca
     2461 gtaatgtcac cacggtttgt tttgataaca gcttttggtc ctttttcact ttttaaatct
     2521 agttgtggga atgccatatt gtttcctcct aatatttgca tacttcataa taataataac
     2581 ataataccta acctctcgta aaaatactag atttgttttc ttttattttt catcactaga
     2641 tacattctat aacttaccgt ttcgatttcg aattcaaaca tttttgagaa gcattctcaa
     2701 ttaaattctg ctatagtgtg aaaagggagg aatttttatg gaaatctatg acattacaat
     2761 catcggtgca ggtcctgtag ggatgtttgc cgctttttac gcaggaatgc gccaagctaa
     2821 aacaaaaatc attgacagtc tacctcaact tggtggtcaa ttagcaactt tgtatcccga
     2881 aaaatatatt tacgatattc ctgggtatcc agcaataaaa gcaagtgaat taatcgatca
     2941 attagaaaaa caattaacta cttttaacca tacattccat ttaaaagaag aagttctctc
     3001 gcttactcgt gaagacgaag ttatcgagat tactacaaat aaaggcatcc attattccaa
     3061 agcagtcatt ttagctttag gaaatggttc attccagcca agaaaattga atttagataa
     3121 tgctgaatca tttgaaaacc acggattgga ttatttcgtg aatgatttga tgaagtatgc
     3181 tggaaaaaaa gtcgctattg ctggaggtgg tgattctgct atcgattgga cgttgatgtt
     3241 agagcctatt gcaagcgaag tttacttgat tcatcgtcgc ccggaatttc gtgcgcacga
     3301 acatagtgta tcacgcttga aatcttcatc tgtcaacttg cttactccct atctcatcga
     3361 tggattatca ggcaataatg gggaactgac agatatccgg ttaaaaaaag tgaaaagtga
     3421 cgagacgatt gatttgatga ttgattctct gatcgtcaat tatggattct cttctaattt
     3481 agaacatctt tcttcttggg gacttgatag taccagaaat gccattactg taaaatcaga
     3541 tatgtctact tctattccag gcgtttatgc agctggtgac atctgtacct atgaaggaaa
     3601 agtgaaactg attgctactg ggctcggtga agcacctact gcagtgaaca acgctttaca
     3661 ctatattaat ccaaaggaac gaactcagcc tggtcacagc acaagcttat acgataaaaa
     3721 tcttcgtcct agttgatttt ttatatctct ttgcatttca agttaaaccc gaaagcagtt
     3781 tcttgcattt ttttcatgtt ccgttaacat gaaatagaga aagaaaaaat aaagggggag
     3841 caataatatg gtcgtcaaaa ctgagacttt agaagaaaag gcaagagaac tattgaagga
     3901 acgtggcgta actgtagaag atatcgcaca acttgtcatg tttttacaaa aagactatat
     3961 ttctgatttg actttggcgg attgtactga aagtgtcaac agcgtgctaa caaagcgtga
     4021 agtacataac gccattatca ctggaatcca attagatata ttagcagaaa agaaaaaatt
     4081 gatgagtccg ttgcaacata ttatcgaaga tgacgaaggc ctttacggta tcgatgagat
     4141 cctagccttg tcaatcgtga atgtttacgg tacgatcggc tttacgaatt atggttatat
     4201 cgacaaggtg aaacctagta ttttaaaaga actaaacagc cacgatggcg ttcatgtcca
     4261 taccttctta gatgatatcg tcggagcgat cgccgctgct gctgccagtc gattagcaca
     4321 caaagaacca gaaaaaagaa gtcgccttac tcaataattc aacaaaaaaa gaaagaaaac
     4381 gtctatttag acgagttctt tcttttttgt ttgtttcaag ctattttttc ctaagaaaag
     4441 aaaaacagca aaaaataatt ctaataatac aaaaaataag ataaagctat gca
//
LOCUS       DADQCX010000147         4381 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.152, whole genome shotgun sequence.
ACCESSION   DADQCX010000147 DADQCX010000000
VERSION     DADQCX010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.152"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..142)
                     /locus_tag="J8R83_002661"
     CDS             complement(<1..142)
                     /locus_tag="J8R83_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9575762.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQ"
     gene            complement(183..437)
                     /locus_tag="J8R83_002662"
     CDS             complement(183..437)
                     /locus_tag="J8R83_002662"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9575763.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
     gene            complement(548..802)
                     /locus_tag="J8R83_002663"
     CDS             complement(548..802)
                     /locus_tag="J8R83_002663"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9575764.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(995..1270)
                     /locus_tag="J8R83_002664"
     CDS             complement(995..1270)
                     /locus_tag="J8R83_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAZ9575765.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1242..2195)
                     /locus_tag="J8R83_002665"
     CDS             complement(1242..2195)
                     /locus_tag="J8R83_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9575766.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2807..4300
                     /locus_tag="J8R83_002666"
     CDS             2807..4300
                     /locus_tag="J8R83_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAZ9575767.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
BASE COUNT         1438 a          754 c          734 g         1455 t
ORIGIN      
        1 attgctttac ccatttgtca aatgctgaag ccgttagttc atattctcga atgatttcta
       61 cacgtggctt tccagctaag taaagattga cgatttgttg cttgaattct tgtgaaaaag
      121 ttcttcgtgt tctcttagac ataaaaattc ctcctggtat gttttcttct agtctacaca
      181 ccttaatttt tctgtctagt taattgtagc ctatccatga tcggtttatt agacctttga
      241 ggtctatatt ttttaactac aatcgacctt aaatttaatt gtttcattag cttttggaca
      301 tgtttaagag atactgaaat cccttctttt aataaaactt gatggatctt tgtggcacca
      361 tagcgttgtt tattcgtaaa aaaaattgtt gaaatcttct ttttcaactt attatttctg
      421 atttctgtag ctgtcaacgg tttattctta taaaaataat agacacttct agggatttct
      481 aataaccgac acaacaaaga aacagtgtaa tccttacacc atttttcaat aaattgaaca
      541 agcgaattta ggttttccga gagaatatgg ctgcggcttt ttttaagatt tcaagttcct
      601 catttaaacg agcattttct tttctcagtt cagctacttc ttttccagtc agtcctgtgg
      661 actgatcagg taaatataaa ttcttccatt tgtaaatcgt tgcttcagat aagccatatt
      721 ctttcgctaa ccctcgaaca gaacgtccag tttgattcag ttcaacaatc atttgtttaa
      781 aattttcttc atatcgggtc ataaaaattc atcctctcgt agataagttt aatttattct
      841 tgtctctacg aaaagctgtc taagatttga tactaacacc aaatgttgta tacccccaaa
      901 caatacacat attttgaagg attaggatta ataaagctaa aaatatagta agtatactaa
      961 atatatttac tatatctagt atacttacta tattttaatc ttttgatcgt ctattatata
     1021 taatccgttc ctcgtcgttt aaagtatcaa cataggcgtc cattgcaagt ttgactattt
     1081 catacatagg aatatctttt gcataactaa gatcccgaat ggtttttagt acgggaggat
     1141 ctacttgaac tggttttctt tctttcgcag tgtactttcg ttcccctaac tcgacattaa
     1201 tatcatcttt aattgaaata tcttcagcac caattttctt cttatctttg ttcgttggta
     1261 ataatgccat ttagtttaat ctcctttcca agaggtagga tatgattggc cattgagtca
     1321 gcatatttag gtgtataatc aaatccttca atatcaccat gttgttcata gtattcaatt
     1381 ctttcttcta attctgtaaa gatgtctgca aaaatagccc accatcttcg atctacataa
     1441 tcatttaatt ggataccatt ctcaccatac atttctaacc gatccgagcc tttaacaatg
     1501 cttttaaaaa tgtttgattc accatactta tcaattgttt tttgatagtt tgcgtgttga
     1561 gaggaacgtc gcactgagaa aagaacaggc aaaattccaa tgatttgaag atgagactct
     1621 tcaaaattcg tgacaatcgg aactaaaact ttattaataa aatcttctgt tccttccatt
     1681 gcgtaccgtt ttaattcttg cattgcaata atataatctg cagcagttaa gaatgcacga
     1741 accacattat ctgttgatgg tgggcagtcg ataaagatat aatcgaaatt ttttctcaat
     1801 tcttctaaag gtttaatgaa ggccaatgat ctcttacgac gatcaggata tttttcggac
     1861 aagtattcat taagttcttc agatccagga gagccagcca taatatataa atgtggactt
     1921 acttgagtaa tacctgaaac ccagtcccct tttttgattg ctgcagacat ggatcgatca
     1981 aagctagtaa tttgatacgt tgatccaatg ttggaagtag tatttctttg ttggtcataa
     2041 tcaattagca acacgtcttt ttcaaaaagt tgactagaaa caatcgctaa taaatcattg
     2101 tctgtagtct taccaatgcc gccttttcta cctgtaagca ttacaacttt tcctagttta
     2161 tctgatgttt taaatgcagt ccgtaagttt tccatagttc cctccaattt cctatactaa
     2221 atatatttag tatacttcat atacttaata tattcgatat atctaatata ctccaaattg
     2281 ataagaattc agactttata aggaatatag tggatatact aaatatattt gctatattca
     2341 gtatatcaga tatattcaaa atgtcaaaat atatttgtgc gttttgcgtt gacaatttag
     2401 agtgaaaaga ggtaaactta attctataga aaccacagat aattcactat ttacaaagta
     2461 gcaaaagcag tggtactctt taaacagaaa aattacataa aaaaaagaga cggaaataat
     2521 tgattttagc agaatcaatt atttctgaat cacatggtta ggacatgtgt tcacgctcgt
     2581 ctcaagaata tgtaagtagc taccaactac ttatattaaa agttgatcgg ataccttttc
     2641 cgattgcctt tattctacca aaaaaaggcg agcaactcaa cagaagaacg tttatttagt
     2701 gtacttaaat taaatattct taaacactga agagagaaca catactatgg ctgagattaa
     2761 agctaaactg tgttctcttt ttgtttgaga aaggacgtta caatcgatgt tgagcgaaat
     2821 ttattcagct attcttaaaa acggcttacg tacatacaaa tatcgaaaca gcaccatgaa
     2881 acctgcaggt catattgatt ccagtaggag tggtgctatc tttgcgtacc gtagcaagca
     2941 attaatgaat gttgggcgtg gtatggtcat tacttcggaa gaagctattt tagagaacga
     3001 aaagaaacta acgcattgga cacctaatac ctatcgcttt ggtacttatg cggatgatta
     3061 tcgaacagtg gttaaaggtc attctgagaa aaacttaagt caaatcaaca catttgtagt
     3121 tgatatcgat tcaaaagaga accatcaagg cgaaattatt ttagcctgtt tagatcaagt
     3181 gggctacatg ccaacgctaa ttttagaatc agatcatggt tatcaagttt attttgtact
     3241 aaagacacca ggctatgtca caaagaaaag caatttcaag gtgatcgatg tagcaaaaaa
     3301 aatttcaaaa acaattcgtc tacagttggc tgaaaaattg tccggagtgg atctaggatg
     3361 taaccacttc ggaattgctc gattcccaca agaaaataat attgttttta aagaaatgaa
     3421 ctatcagtat tcttttgctg actggattca atggtcgatg aagcttgaat cagatcaaaa
     3481 aacaaaagaa gatcgagaac gaaaactaat tgtctttcct gagaaaaaag aaattcgtca
     3541 agtagatgaa ccgtggttcg atatgttact tcataaagca aacatcgtcg gcggagaagg
     3601 acgtcttggt cgaaataatg tgattttcac gctttcttta gcttattact cttcaggtta
     3661 tgcattggat acttgcgaat acaatatgtt cacattcaac gaacggttac aggaaccgct
     3721 atctgaagca gaattagtaa agattgtacg tagtgcttat tctggtaatt atcaagcagc
     3781 aagcagagaa ttcattattg aattgtgcca gcaatgggtt tcaccaacct taaaaaataa
     3841 tgatctgttc attcaacgac gtggctggtg gaaatttaaa aagccacgag atcaaagaaa
     3901 atatagtcat aaaaatgaat ggaaagaaga tctattggct tatctaagcg aaaaaagtct
     3961 tgctagtgag ccttatttga acctgtcaaa aaaagaattg gcttcacaac taacgatgcc
     4021 caagcgaaca cttgataaga tcttaaatga gttacgagag gagaataaag tcttctacaa
     4081 ggtaacacga ggaagaaatg gcggaatgat cattgcttca gtcaaaacgt tgttcgcgag
     4141 ggttattcaa ctaagtaaag aaaagagact agattattca acaaggatca cagaggtatt
     4201 tggactcaac gagagcttag tagaagagac atttagacaa ttatcaaccc ccttgaaccc
     4261 tcttaaagaa gtgaatcttt ttgaagtaga tacaggttga aaaataaaag gtgcaaattg
     4321 ccttatacaa tatatctatg atacttctgt aggtgttgct ccctttgcct agctacgtgt
     4381 a
//
LOCUS       DADQCX010000148         4354 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.153, whole genome shotgun sequence.
ACCESSION   DADQCX010000148 DADQCX010000000
VERSION     DADQCX010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.153"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="J8R83_002667"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="J8R83_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAZ9575768.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="J8R83_002668"
     CDS             complement(2944..3378)
                     /locus_tag="J8R83_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575769.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..>4354)
                     /locus_tag="J8R83_002669"
     CDS             complement(3395..>4354)
                     /locus_tag="J8R83_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAZ9575770.1"
                     /translation="GPFRANNIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLGD
                     IRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLYE
                     NKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLGM
                     DIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQF
                     IGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNHT
                     ISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT         1337 a          815 c          601 g         1601 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gacc
//
LOCUS       DADQCX010000149         4335 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.154, whole genome shotgun sequence.
ACCESSION   DADQCX010000149 DADQCX010000000
VERSION     DADQCX010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.154"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            147..2087
                     /locus_tag="J8R83_002670"
     CDS             147..2087
                     /locus_tag="J8R83_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAZ9575771.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            2174..4096
                     /locus_tag="J8R83_002671"
     CDS             2174..4096
                     /locus_tag="J8R83_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAZ9575772.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
BASE COUNT         1463 a          728 c          890 g         1254 t
ORIGIN      
        1 attttattca acataataaa tcgtatatca atttttttag cgaaatttct atttattcca
       61 agaatttcag ttattacgga atcattttgt gcttaataaa aagaaaccgt ttttatatac
      121 tataaatgta gaaaggcggt aggaaaatga aaaaaattat tgcaatcaca tcctgtccag
      181 ttggtattgc ccatacatac atggcagcag aaaacttaga gaaagcgggg aaagcagttg
      241 gcgccgaggt aaaagtcgaa acacatggtt ccatcggtat tgaaaatgaa ttgactgcaa
      301 gagatatcga agaagcagct ggtgtaatca tcgcagcaga tactaaaata gataaatcac
      361 gattcggcgg taaacctttg ataaccgtag gtgtgcaaga aggaatccac catgcagatg
      421 agttggtgag agatatttta gcaggaaaag cgccagtcta taaaagtacg gaggcaatta
      481 tttcttccga aaataaaagt gaatcagaaa atttaggtaa aaaaatctat aagagtttga
      541 tgaatggcgt ttcgtacatg gtacctttcg tagttacagg agggttattg atcgcgattt
      601 ctttaacatt aggaggaaca gctacacctg aagggatcaa gataccagaa ggaacgattt
      661 gggcaacgat gaatagtatc ggaagtatcg ctatggggtt gatggttcca attctatctg
      721 catttattgc gcaaagtatt gcagatcgtc caggacttgt tcctggattt gttggtggga
      781 tgttagcggc aaacggagca ttatatggta gtgatgcgaa tgcgggattc ttaggcggga
      841 tcatcactgg atttttagca ggattcattg ctttaggaat caagaaagtg cgagtaccga
      901 aagctttaca atcgatcatg ccaattattg ttatcccaat tttaggatca ttggcagttg
      961 gttttgtgtt tatctatgtt attggagaac cagtagctct tctatttagt tcattgactc
     1021 actttttagc agggatgcaa ggaggaagtg aaattgttct agctatgatc ttaggagcga
     1081 tgattgcttt tgatatgggg gggccgttca ataaagtagc ctttttgttc ggatctggct
     1141 tgattgcaga aggcaattat tccattatgg ggccaattgc tgtagctatc tgtatccctc
     1201 cattagcatt ggggctggca tcattgattt taaaaaccaa atttacgaaa acagaacgag
     1261 aagctggtaa ggcgtcctta gcaatgggac tgtttgggat tacagaaggc gctattccgt
     1321 ttgcttcaac agatccacta cgggtgattc caagcattgt aatcggggca atgacaggaa
     1381 gtgtgatcgc gatgctttca ggagtgacag atcatgtagc tcatggcggt ccgatcgtag
     1441 cggttttagg agcagtggat cacgtagcca tgttttttgt agcagtgatt gctggtattg
     1501 ctgtaaccgt gctaatgtta agaatcctta aaccgacatt acaacaaact gcggttgctg
     1561 cagcaaatgg tgtgacagta gcagatctat cagagactga aacaagtgat gtttatacga
     1621 aaactgaaac ttttgattct atcacggata ttatgtcaga tgaagcaatc gttttaggtg
     1681 aaacagcaac aacaaaagac ggagtaatcg aagatttagt ccaacgttta gaaaaaacag
     1741 cggcgatcac agataaaacc agatttaaag aagtcatcta tgatagagaa catgaaagta
     1801 caacgggaat cggtatgggg attgctattc cacatggaaa atcagcttat gttcttaaac
     1861 caacagtggc atttgccaga agtcaatctg gggtagattg gcattcttta gatggaaaac
     1921 ctgcacatat gatctttatg attgctgtac ctgaaaacag ccaaggtgat atgcacttga
     1981 aaatactgca acgtctatca cgtaaattga tggatgatga cttccgtcaa gcactgatgg
     2041 aagcgccaga taaaacaaca gttcaccaat tattaagcga aatgtaacat aagatgaaaa
     2101 atcgaccgtg atgagacata atagatgtgt tatcatgatc gattttttat ttagaaggga
     2161 gtttctgcac attatgaatc agcgtcagca atctttgatc tatcaattaa gtgagaacaa
     2221 taattatata acaacaaaaa agctagcaga gcatttccat gtgtcagaaa gaacgattca
     2281 tagcgatttg aataccattg aaacttggtt gagagacaaa catctgcctt taatgtttga
     2341 aagaaaaaaa ggtacaggta tcttgttgaa tggtctgcct cacgaaaggg aacaactgaa
     2401 acgagcgctt aatgaagaga ctcaaacaga aatggataaa aaacagcttc gtcagttatt
     2461 gattttccat ctgctagtag caaaagacgg atttagtctt gaagaacttt cagaaaaact
     2521 atatgttgga aaacgtacga ttcgtaaaga attgacagag ttgcaaagct tttttgagta
     2581 tcaccattta cagctagtat ccaaaacaaa actaggaact tttcttaaag gcgatgaaca
     2641 agaaaaaaga cagttgcttg ttaagacatt acgaaatatg cagaaagaag atccacaaag
     2701 tccgtcgttg aaagaattct tcgctaaaga tacattaaaa gttatccaac atacattaca
     2761 agatgttttt tatgaaaacc atttagaaca gccgaatgga ctggctagtg tggagattca
     2821 catctacttt atgctcgagc gaatgaaaca gtaccagaaa gtgaaattaa gtaaagacga
     2881 aaacgaagtc gtggaacaca cccaagcaca aaagttaagt agtcaaatat tagcaaaact
     2941 agccaccatc tatccaattg aattttctcc tgatgaaatc aattatctgg ctttgcgtat
     3001 cgccaatctt tttacaaatt cacaagcagc cacacgtttt caaaaggaat ctagcgcact
     3061 tgctgatcat ttgatcgaac aagtggaaca gtttctaggc tattcattaa aagaagatca
     3121 gctactaaaa caaaatttaa ggtctcattt atcttcaact tattttcgac tccattatgg
     3181 tttgcagatt tctaatccat tgacgaaaaa tgtgtttagt acgtacacac aacttttctt
     3241 agttttacag ttaattttag aagattattt tgaaaaggaa aatttttatg ttccacaaga
     3301 ggagacagct tatttaacga tccatttcca agcagcgatc gagcgacaca aacatcagaa
     3361 aagtagaaga tatcaaacgg ttttagttag tgaatattca aaagctatgg ctacttttct
     3421 cgaagcacgg ctgaacagag aacttccaga attaacgatt atggatctag ttgaatataa
     3481 gccagaatta aagagacaag attttccctc tgttgatttt atcttggcta cgttaccatt
     3541 taaacatata agcattccag taatcgagat ctcaccaatg atcacagaaa ctgatctagc
     3601 ctatttgaca aaatatatgc tggagcatgt gcctatcaag aagaaaaaaa catttgatct
     3661 agcaagcttt actcatccat ttctgatctt tcctcaactt gaacggacag acccagccga
     3721 tattttaaac tttatgggaa acgtcttagt ggaacatcat tatgtggagc cggaattcat
     3781 cgattctgtc ttggaaagag acagtcactc cagtactaga gtagcaccat ttgtaacaat
     3841 ccctcacggt aatccgctgt atgtgaagca ttcgatgatt tctattgcta caatgaaaga
     3901 accagtccta tggcacgggg aacagatacg tatcgtactg ctattagcaa taaagaaaaa
     3961 tgatttgaaa catgcagagt tcaaaaaaat attttctgtt attcactatc tagaaaagca
     4021 gccagaacaa atggctcagt tgatgcaatc caatcatccg ctagaaatct taacgttgtt
     4081 atctagttat gaataagtag cgattaaaaa actgccttta tatttataat aattctatct
     4141 atttatttgg aagtagaaaa ctaaatacaa aaaaagagga tgtggccaaa gttgtggcac
     4201 atccttttat tttgagtttc ttataatttt ttatagttgc ttacgatgtc ttgactactg
     4261 gtaaacggtg ttcaagagac aatttgtcgg caataaggca caattttgta aaatatggaa
     4321 agctattttt ttaac
//
LOCUS       DADQCX010000150         4305 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.156, whole genome shotgun sequence.
ACCESSION   DADQCX010000150 DADQCX010000000
VERSION     DADQCX010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.156"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            148..1137
                     /locus_tag="J8R83_002672"
     CDS             148..1137
                     /locus_tag="J8R83_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAZ9575773.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="J8R83_002673"
     CDS             1134..1553
                     /locus_tag="J8R83_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575774.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1562..1870
                     /locus_tag="J8R83_002674"
     CDS             1562..1870
                     /locus_tag="J8R83_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575775.1"
                     /translation="MDKIDLREETVNRIEVMYERLADYLNLSDEDNYSEMLERMMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQISVINSKEKGM
                     "
     gene            1874..2236
                     /locus_tag="J8R83_002675"
     CDS             1874..2236
                     /locus_tag="J8R83_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575776.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="J8R83_002676"
     CDS             2458..3864
                     /locus_tag="J8R83_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAZ9575777.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1497 a          602 c          996 g         1210 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgtgagaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttta
     4021 aagggtgcgg ttttatgttt gcatgactaa gaatgagtgg gaaaatttaa cagccctatc
     4081 taacaggcgg ttaaatgtac aaaatatgta caccccctta aaaatgcagt ggtcgattga
     4141 tcgaatttta tgtctttggg ttttggggtt ttaaaacgaa aaaaaggggg cgattttcgc
     4201 cctctttttt gatgtttttt cttatcttga tactataggc aactatttct gcgaagaaat
     4261 cggggctata gtatgggtct atcccttgtg gctctaagga agaac
//
LOCUS       DADQCX010000151         4254 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.157, whole genome shotgun sequence.
ACCESSION   DADQCX010000151 DADQCX010000000
VERSION     DADQCX010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.157"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            832..1755
                     /locus_tag="J8R83_002677"
     CDS             832..1755
                     /locus_tag="J8R83_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9575778.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            1771..2310
                     /locus_tag="J8R83_002678"
     CDS             1771..2310
                     /locus_tag="J8R83_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAZ9575779.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
     gene            3573..4007
                     /locus_tag="J8R83_002679"
     CDS             3573..4007
                     /locus_tag="J8R83_002679"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575780.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
BASE COUNT         1614 a          638 c          697 g         1305 t
ORIGIN      
        1 ttatgagcaa attaatgcaa aatttggcta gcaaaaaagc taaaaaatat atgctaataa
       61 tcgagcgaaa taaacacttt ttcaagtgag cgaatccgcc atgacaaagc tgaagcagtt
      121 tatttcagct ttgtcatggc gtgtgccgac ttttttaaaa gtctaggcac acgagcaaat
      181 atctttatca agctctaatt tgcgttttaa gacgtttgaa acgcctaagt atataaatat
      241 ataagaatag gtttaagagt gcttaaatcg aattttagag ggcatttaga caattttagg
      301 gttgttaggg cttgccctga ccgcctgtaa ggcgttttaa gaacaagata agggatttat
      361 actaggactg tcttaaaatg tcttaaacga acgctcagag cttctcaaag ggttccttat
      421 gaacggcttt tagcaaagga gccggaggcg actgcgcagt ataatgtgag agcagagcga
      481 tcacaccttt ttagcgaacc gtagggagca aggtttggaa ttggcagttt tgataaattc
      541 gcgaacctgt ttagagaaaa aaggagtgat tttttaggcg ggaaaattag cctcccctct
      601 ttttatatct ctttttatat ctctttttat atctctttta tgtcggctgt gtccttactc
      661 tcccaagcaa ttcagagttt tttcaagtag gttttctacg cttttcaagt aggttttcta
      721 cgcttttcaa gtaggttttc tacgcttttc aagtaggttt tccgacatta ttgagtattt
      781 ttataaagta tgttactttt atttcatact ttataaaagt aggagaagct tatggcaaat
      841 gaaattgtaa aatatgaaaa tagattaaat catattcctc tgagaaaatt taatagtcgt
      901 gaaatgaact tatttttttc aattgcttca cgtgtacgtg aaaaaggtgt agatgagatt
      961 attttttcat ttcacgattt gaaaaaacta agcggttata cagaacgtgg ggaacaattt
     1021 ataaaagatc ttagtagcac gtatgacaaa ttattaagta ttaatgcttg gaatgatgat
     1081 ggaaatactt taactaaatt tgttgctttc acaaaatata gcattatacg agataaacaa
     1141 cttgttataa tttcagttaa tccagaattt aaaggacttt ttaatcaatt aaagaactgg
     1201 acaagattta atctagagca atttactaat ttggatagca catattcaaa aactatgttt
     1261 cgattattaa aacaatatcg aactcaaggc tggactgaat tttccaaaga aaaatttttt
     1321 gatttactag atattcctaa aagttattgg aatagtccgt caaatattga caaatttatc
     1381 ttaaggccaa ttaaagaaga actcactccc ttatttaaag gattaactat tcgtaaaaaa
     1441 tatggtaaag gtcgaggtaa acctgttatc ggttatcgtt ttacttggaa agctgaaatt
     1501 aaccatgctg acgatttttc caaagggaaa caagaagatt tacgtataaa attatttaat
     1561 attgatcaca atggagaatt aacacgagaa gaaaaatggc gcgctaaaga tcgaatacta
     1621 aatcttccct taggcactca tgaagctgat tttaaacaac aacaacaaac tgaagaaaaa
     1681 caggcagaaa aacgagaact ttcaaacaaa ctcaaacaag atttactagg aaatttacaa
     1741 aacttattcg attaagctta aggagtattt atggcagata aaacaatcaa agaacttgcg
     1801 gaagaattag gagttagtaa aacagcaatt aacaaaaaag tttctgacaa aaatcgaaaa
     1861 ctttggtttg caaaaaacgg aaacaagttt gtgattaacg aaaccggtca aaaagctata
     1921 aaatcaatgt ttttagtcga taacgcaaac ttaaatcgaa aactagttgg cgaaaaatca
     1981 aaaaccaaaa accataaaaa caccaaccaa gtttccgaat taaaactcct ttctttccta
     2041 gaaaaacagt taaatcgaaa agatatacag ctacaagaaa aagataatca aataaaacaa
     2101 atgcaaaaat tactcgacca gcaacaacaa ctcactctac aagcgaacca acaaattgag
     2161 aacctacaag aacagctcca tttaacttat acagaagaaa ctccaacaac cgaatcaact
     2221 gccttttctg aaaaaaaagc agacaataca caaccactta ttgaaaaaaa gtggtggcaa
     2281 atttggaaat ctaatagaac caatctctaa aattttctag aagttagttc ggatagtaga
     2341 ggaaaaagtt gtactacctg atggggagat cactcaaatt tttatgagaa agaaaaaata
     2401 gtttacaact gtaaacaatc aatgtttata gttgtaaact atcaaactat atggtgactt
     2461 attgcttaaa ataggttgaa atctcactca atttttggtg gaaaaacaaa ataaattcta
     2521 atcgattttg ttgaaaaagt cataaaaaaa caaatgtgat tttaacaaaa tttcaaaaaa
     2581 atcgtttgaa atttcgttta ttttttttga gaattttgat catcgtaggg tcattgtaga
     2641 atcattatga gatcatcgtg ggatcatcga ataaagtatg ggaaaggctt gcggtgcttg
     2701 gtattaaggg cattctccgc ctcccaggtt cttgaccatt ttctctcaac gtggtaaaaa
     2761 tcccacttat aagagaaaat ggtcaagaac ctaaacggtc ggcgaagaaa acataccaag
     2821 caccacaagc aaaaaaagtt agagtaactt ccaaaaaaga aaaatttttt agaacaactt
     2881 ttgaaaattt aattttgatt tatatccgtt caatttaaac atttgataaa ctgaaggcta
     2941 gtatttaaaa tgtgtataca agtggtagcg ttaaaaaaag tggaggtata acctatgtta
     3001 aaaaaaactg tgttggtact gggttctatt tctctaggaa tattaggttt tagccccatg
     3061 ctattatccg taattggaaa aaacaattcc aacggagaac ttaaattaaa ttcaaattat
     3121 tacaacagtc ctaacgaaga attgtttgta aaagagacgg ataaataata aaaaagactg
     3181 ctctttcgag cagccagtta aaaaataatg agtgtttatt cttgaaaaag caacgcgctt
     3241 atgaagcgct accaaaaatt tatcatattt tatgaaaaat aacaccccag taaaaaatga
     3301 ctggtaaaaa ttcacaaaga aacggaaaga agcaactgca gaaaatcaag ccttaaaaag
     3361 agcttttgac ttagaccaat cgaaaatcac aaagtgagcc cctgtatccc ttggtagaga
     3421 ggctacttgg catagtacac attatgtcta ctaaccttta aaataacacg ttttataaaa
     3481 taaaccctct tgacaatatt taattttctg attattctaa atatatacag aaagcgcttt
     3541 cctaggattt tatatctaag gaggaagtaa caatgaaaaa taaaattatt aaaattatta
     3601 cttgtctatt tttgttcggt atgattgttg gagcaagtac tccgttaaat ctgtttcctt
     3661 ttagtgctag aggtataaaa gtggaagctg caagttcacg atataatcat aatcatcgtg
     3721 gatttacttg ctataaaatg aactattatg ttactaataa aatgtgtaga gatttgaaaa
     3781 aaaattataa taagctaaag actcctgctc aaattgcatc ttttattcct attggtggag
     3841 ttggaacatg ggttattaca aatgctttta gtagtgctgt tgatgcaatg aatgtctttg
     3901 taagagctgc aaatcaagga aaaggtgtac aattaacata taatgctcac tttagcaata
     3961 caacatcata tcaatacaat gattacgctc gttatgtaat aaaataatca gaaagtgaaa
     4021 ctatctcatg aataaaaaga ttttagctgt aattatttca ataatagttt taatcactat
     4081 gttcttcata tttaggctaa ttttcaatat aagcttacaa aaaagtattc tttatctaat
     4141 tcctatagca tttatcttag caatttttag aagtatttac ggaaataaaa actctaaata
     4201 gctaaaaata aatcatacta aattttacaa aaagtggcta gcattttcta gcca
//
LOCUS       DADQCX010000152         4234 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.158, whole genome shotgun sequence.
ACCESSION   DADQCX010000152 DADQCX010000000
VERSION     DADQCX010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.158"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(37..1257)
                     /locus_tag="J8R83_002680"
     CDS             complement(37..1257)
                     /locus_tag="J8R83_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAZ9575781.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1882)
                     /locus_tag="J8R83_002681"
     CDS             complement(1277..1882)
                     /locus_tag="J8R83_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAZ9575782.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="J8R83_002682"
     CDS             complement(1931..2863)
                     /locus_tag="J8R83_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAZ9575783.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="J8R83_002683"
     CDS             complement(3284..4144)
                     /locus_tag="J8R83_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575784.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1203 a          853 c          695 g         1483 t
ORIGIN      
        1 tttattcttt atttaaagct ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgagaatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aattggttaa gata
//
LOCUS       DADQCX010000153         4232 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.159, whole genome shotgun sequence.
ACCESSION   DADQCX010000153 DADQCX010000000
VERSION     DADQCX010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.159"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..359
                     /locus_tag="J8R83_002684"
     CDS             <1..359
                     /locus_tag="J8R83_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAZ9575785.1"
                     /translation="FMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNN
                     AYCINEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSE
                     INNFLNEESSDERKQI"
     gene            340..1074
                     /locus_tag="J8R83_002685"
     CDS             340..1074
                     /locus_tag="J8R83_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9575786.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1107..2015
                     /locus_tag="J8R83_002686"
     CDS             1107..2015
                     /locus_tag="J8R83_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAZ9575787.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2012..2554
                     /gene="sat4"
                     /locus_tag="J8R83_002687"
     CDS             2012..2554
                     /gene="sat4"
                     /locus_tag="J8R83_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAZ9575788.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            2647..3441
                     /locus_tag="J8R83_002688"
                     /note="aph(3')-IIIa"
     CDS             2647..3441
                     /locus_tag="J8R83_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAZ9575789.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(3549..3737)
                     /locus_tag="J8R83_002689"
                     /pseudo
     CDS             complement(3549..3737)
                     /locus_tag="J8R83_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3717..>4232
                     /locus_tag="J8R83_002690"
     CDS             3717..>4232
                     /locus_tag="J8R83_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9575790.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
BASE COUNT         1447 a          635 c          969 g         1181 t
ORIGIN      
        1 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
       61 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
      121 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
      181 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
      241 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
      301 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
      361 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
      421 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
      481 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
      541 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
      601 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
      661 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
      721 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
      781 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
      841 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
      901 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
      961 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     1021 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     1081 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     1141 tttctttagc agaacaggat gaacgtattc gaattgtgac ccttgagggg tcacgcgcaa
     1201 atattaatat acctaaagat gaatttcagg attatgatat tacatatttt gtaagtgata
     1261 tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata ataatgatgc
     1321 aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc tatcttatgc
     1381 tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag ttagataatt
     1441 acctaaaggg cgataaatta ataaaggttc taattgataa agattgtaga attaaaaggg
     1501 acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg gagtatgatg
     1561 attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg tgccgtaagg
     1621 aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg ctgagaatga
     1681 tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag aactataagt
     1741 ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc taccggatgg
     1801 attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc agggcggtat
     1861 ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg aatataacaa
     1921 aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg gatagcacat
     1981 atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag cagggcacct
     2041 gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta taccgaggta
     2101 tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt taaaaagcta
     2161 ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata ttgacaatac
     2221 tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag ttaaactgcg
     2281 aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg atttcagggg
     2341 gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc ataaaaactt
     2401 gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat tctatcataa
     2461 ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg aaaacaactt
     2521 tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg aattggagtt
     2581 cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag aggaaggaaa
     2641 taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga aaaataccgc
     2701 tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt gggagaaaat
     2761 gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta tgatgtggaa
     2821 cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac
     2881 tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc
     2941 tcggaagagt atgaagatga acaaagccct gaaaagatta tcgagctgta tgcggagtgc
     3001 atcaggctct ttcactccat cgacatatcg gattgtccct atacgaatag cttagacagc
     3061 cgattagccg aattggatta cttactgaat aacgatctgg ccgatgtgga ttgcgaaaac
     3121 tgggaagaag acactccatt taaagatccg cgcgagctgt atgatttttt aaagacggaa
     3181 aagcccgaag aggaacttgt cttttcccac ggcgacctgg gagacagcaa catctttgtg
     3241 aaagatggca aagtaagtgg ctttattgat cttgggagaa gcggcagggc ggacaagtgg
     3301 tatgacattg ccttctgcgt ccggtcgatc agggaggata tcggggaaga acagtatgtc
     3361 gagctatttt ttgacttact ggggatcaag cctgattggg agaaaataaa atattatatt
     3421 ttactggatg aattgtttta gtacctagat ttagatgtct aaaaagcttt aactacaagc
     3481 tttttagaca tctaatcttt tctgaagtac atccgcaact gtccatactc tgatgtttta
     3541 tatcttttct aaaagttcgc tagatagagt tctatattag agatgtaaag agttttggtg
     3601 aagaggtttg tgagtatggc ttttataacc agggtgcaat gagaagcact aacagcagct
     3661 agcttaagaa cgcataggat atacttttta tggaagtcac agaggaggaa taaaatttga
     3721 acaggattaa cagagtaacc tctattctta ttcagctgca atcaaaaaaa ataattcctg
     3781 ccaaagaaat tgcacagcga tttaatataa gcttaaggac agtttacaga gatatccgga
     3841 cacttgaaga agccggaata ccaattggat ctgaggccgg aaaaggatat tttcttgtag
     3901 agggcttcct acttccgccg gtaatgttta cagcggcgga agtgggtgca ttgattacag
     3961 cagggaaatt tttaaattgc catggagatg aatcatttat aaaggatttt gattcagcta
     4021 tgtataaaat caaatctatt ttgaagcatg gtgaaaaaaa ctatgcacag gagttggaga
     4081 acagtattaa cgtgtacagc acatctggac agaaaaatac attggcggat aacgttattg
     4141 cagcaattca gactgcaatc tgcaataaaa gggtaatatc aattcaatat cctgcatcag
     4201 gagggcaaga accggaaagc agaatgatag ag
//
LOCUS       DADQCX010000154         4215 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.160, whole genome shotgun sequence.
ACCESSION   DADQCX010000154 DADQCX010000000
VERSION     DADQCX010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.160"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="J8R83_002691"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="J8R83_002691"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAZ9575791.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="J8R83_002692"
     CDS             complement(1174..1869)
                     /locus_tag="J8R83_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAZ9575792.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="J8R83_002693"
     CDS             complement(1882..2598)
                     /locus_tag="J8R83_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAZ9575793.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3536
                     /locus_tag="J8R83_002694"
     CDS             2928..3536
                     /locus_tag="J8R83_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAZ9575794.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3861..4184
                     /locus_tag="J8R83_002695"
     CDS             3861..4184
                     /locus_tag="J8R83_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAZ9575795.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
BASE COUNT         1219 a          837 c          761 g         1398 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcaaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aagaaagcac aggtgaaggt ggcgaaccag aagtgatcgg ttcaacagaa gaataatact
     3541 gaaacaatca ggtggtgtta gaagcggcgg gtcagcagct tttaacacgc cttttttatt
     3601 tctaatcgtt tattttcata tggggcttcc acttttgtaa atggctttac aaacgaaaaa
     3661 tcctaattta ccaagctttt cctcgcatac ttttatcgta cctttataaa aatttatact
     3721 ttgaaaaaaa gtattcaatt attgttgcat ttttcctgat tctttattag aatgaaccct
     3781 cgttgaagta agtatttcta gtttatccta ggattaatta taaaaataaa acattcgttg
     3841 attcgaagga ggttaaacag atgtttgaaa gttttgatag cagccgcaac cgttacgctt
     3901 cagttggtgt cgtatcaagt ttgccagatg aattgattga cagtatatgg tttattattg
     3961 acctagatct taagggagtc attccattag aaaatatatt aacctttgat ttgatcgaaa
     4021 atcgtggaaa agtgacgatg catttttctc aagcaggaag caatgtggaa atggatattg
     4081 atttgccgtt tgcctattcg aaccaatttc ctgctcaagt atacgcctat gatgacggta
     4141 cgagagaaac gatcctttta ccaagtgaga ttagacaata ttaaggtgat agataaacgt
     4201 ggatgtccct tattt
//
LOCUS       DADQCX010000155         4167 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.161, whole genome shotgun sequence.
ACCESSION   DADQCX010000155 DADQCX010000000
VERSION     DADQCX010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.161"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            15..99
                     /locus_tag="J8R83_002696"
     tRNA            15..99
                     /locus_tag="J8R83_002696"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49..51,aa:Leu,seq:caa)
     gene            354..1229
                     /locus_tag="J8R83_002697"
     CDS             354..1229
                     /locus_tag="J8R83_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9575796.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1333..2097
                     /locus_tag="J8R83_002698"
     CDS             1333..2097
                     /locus_tag="J8R83_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAZ9575797.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            2114..3526
                     /locus_tag="J8R83_002699"
     CDS             2114..3526
                     /locus_tag="J8R83_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9575798.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            3543..>4167
                     /locus_tag="J8R83_002700"
     CDS             3543..>4167
                     /locus_tag="J8R83_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAZ9575799.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIY"
BASE COUNT         1358 a          620 c          887 g         1302 t
ORIGIN      
        1 ttatttttaa atttgccggc gtggcggaat tggcagacgc gctggactca aaatccagtg
       61 tccgttgagg acgtgccggt tcgaccccgg ccgccggtat aattatcaat atagcaactt
      121 tcttatagag agttgctata ttttttttgt ttttatgtaa ttacctccaa atcaattcga
      181 tacaagtatt atcataaaac gagtaaaaaa gatattgata acgcttttat tatgtgttaa
      241 actatttttg taaattatgt agggtgctac tattcaatta ggcacgacct aagaaagggt
      301 tctttcttag gtcgtttttt gtctttaaaa attgtttgga gacaaaaata tgtatgaagg
      361 agtctgcaag ttgttttgtt ttatcatata gaggaggtga attaacggtg tatgtgatga
      421 aaaagctgaa tcataatgct gtattgatcg atgacgatgg aatagaaaaa attgcgatgg
      481 ggaaagggat tggcttttct gctaaagtga gtaagccatt tgatgttgag gatgctgaca
      541 aattatttgt attagattct aaagaaaaga tcaaacgatt cagtgagata gtctcgcaga
      601 ttccaatcga atttatggat tttgcggaag aagtgattga actgataaca gctaggatct
      661 cctctccatt agattcaaat atctatatta cattgacaga tcatatttat tttgctattc
      721 aacgaaaaag agaagataga gatgtcacag caattatgtt gccagaaatg agattccttt
      781 atccaaatga atatgatata gcagtagaag tggtcgagcg aatcaatcat cgatatcaaa
      841 ccgagttagg gtcaaatgaa gtaggattca tcactatgca tatcattaat gctgagctag
      901 gagagcctaa tagtttaaag agcttaaaaa tagtagaaat gacgaccacg attttgtccc
      961 atctagaaaa atcctattca aacgtttatg ataaagaatc actgacttat catcgcttaa
     1021 tggttcatat caaattcctg gttaaacgct tgatttatca ggaagaaacg ccagtagaaa
     1081 atattggttt ttttactgaa acatttaaac atagcaaagc gtattgtaca gcactaaaga
     1141 ttaaagatat catcgaacag caatttcaac ttgccattca agaaaatgaa atcatctatt
     1201 tggcaattca tctagcaaga atctattaaa ataagggcgt aactatctat aggcgcaacc
     1261 aaatgacaca tagtaaatgg actatgatta tttggttgcg cctattttag tagaaaaaag
     1321 aaggagaatg aaatgggaaa agtgattttt aattcggatg attttggcta tagccatggt
     1381 gtgaattatg ggattatgga tgcttatcag cgaggaattt tgacatcaac tacattgatg
     1441 gcaaatatgc cgggtttcga gcatgctgtg aaactaagaa aggaaatgcc taggctaggt
     1501 gtaggagtcc atttaacatt gacgtgtggc aaaccactcc tcaaaactgt cgatactctt
     1561 atcgaaagcg gagagttcag atccttatct tattatcagc atccatttaa cattgacaaa
     1621 gatcaactgt atcaggaatg gaatgctcag attcaaaaaa tttatcatgc ggggatcata
     1681 ccaactcatt tagacagtca tcatcatact catactttgg atgaaaatca ggaggtagtt
     1741 gttacattag caaaaaaata tgatttgccg gttcggagca actttgaacg aaaagatgaa
     1801 gttcgtcatg tcgattattt tgagccttgt ttcgatgtcg taggagaaac tgatgaaaaa
     1861 aaacgacaaa tcaatacgag tgtggaagaa tatttggcaa gtttactcat gatattgaga
     1921 gaagataaaa cgatcgaagt catgtgtcac gcagcgtatt tggatcagga attgttaaat
     1981 ggttcaagtt ttgtgtatcc tcgtacccac caagtcgaat ttttaattca ttcagcattt
     2041 gctcaaaaag tgaaaaatga tcctttgatt gagttagtaa catatgagga tatttaatag
     2101 aggaggaata aaaatgaatg ttaaatcaaa tgtgcagaag cttggaagag cgatgctact
     2161 tccagttgca gcgatgccat tagcgggatt gatcatgcgt ttatcagctg acgatatgct
     2221 gaacatccca gtaattggtg cagctggaaa tgccgttttt ggaaacttgg atatcttatt
     2281 tgctatagga gttgcaatcg gttttgtcaa aaataaggac aaaggaatac ctgcacttac
     2341 tggtttttta gcgattgcta ccttgaaaaa aggcttagaa attatggacc cagaagtgaa
     2401 tatggggatt tttggtggaa ttatttccgg tttagtagcg gcatggacgt ataatcgctt
     2461 taaagaacaa aaattaccag tagttttttc ttattttgcg ggcgaaaaat tcccattgac
     2521 tatggtgatg attctacaaa caatcgcagc tgtttttttg ggctttatct ggccgctcat
     2581 ccaaattggg attgataatt ttgcaaaact gctcgttgat atgggagcat taggtgtggg
     2641 gatatttatg tttttgaatc gtttgctgat cccctttgga ctgcaccatg tgttgaatac
     2701 gtatatttat tacgatttag gaagctatac atctcctagc aaggaagttt tcagaggaga
     2761 gatgacacgc tttatcaacg gagatcctca ggctggactg tttttatcag gtttttttgt
     2821 agtaatgatg tttggtatac cagctatatg tctagctatc tataaagcag cttataaaga
     2881 aaataaagag atggtcaaag gaatcatggg aagcggtgca ggaacttcat ttattgcaaa
     2941 tatcactgag cctgttgaat ttagtttcat gtttctttct cctatgttgt acgtgatcca
     3001 tgcacttttt gccggtttag cagggattgt ctgttactta ttcaatatac gaattggttt
     3061 tacattcgga gcatgtattg ttgattatct catcaatttt cgaatcgcta ccaatgctat
     3121 tttgattctt ccaatcggaa ttttcttttt tgccttgtat tacgttactt tttattattt
     3181 gatcaataag agaaacattc agacattagg acgtgaagct aaggcagagt ttggcaatga
     3241 agtaacctta gaagaaacag agttagggtt agcaagtaaa aattatgaat atatggcaac
     3301 aaaaatgcta caagcgtttg gaggaaaagc caatatcctg gatgtctata gttgtaatac
     3361 acgcctacgg gtagaggtag tggatcccac catggtcgag gaacagcgaa tcaagcaatt
     3421 agggataagc gggatcatta aaccaactga aaaaaattat caaattatca tcggcttaga
     3481 agtgacttat gttatggcag aattcaataa attattagaa gaatagaaag gaaaagatga
     3541 tgatgaaaaa acagattatc actatagctg gaggcgggag tacgtataca ccaggaatcg
     3601 ttcaagccat tttgaacaat gaaaaacggt tgccattatc tgaaatacgt ttatatgata
     3661 ttgatgaaga aagaaatatg gatatgtact tgattgttaa atttatgctg aaaagaaaag
     3721 gtttttcaaa tattcgcatt cgtgcaacgg atgatccaaa gcttgctttt acaggatgcg
     3781 attttgtttt ctcacaaatt cgtgttggag gattggagat gcgagaaaag gacgaaaaga
     3841 ttccacttaa acatggatta gtaggacaag aaacgtgtgg actcggagga tttgcttatg
     3901 ggatgcgctc aatcaaaggt ttattggaaa ttgtcgatca tatacaagac tatgccccca
     3961 aagcatggat tttgaattat acaaatccag agtcgatcgt ttctgaagct gttcgtcgta
     4021 aatatccgaa tgtaaaaatg attaatgcct gtgatatgac tatttcaatt gaagaaacga
     4081 ttgcagtgaa ttacggttat gatcgtaaga attggatcgt tacgtattat ggtttaaacc
     4141 actttggctg gtatacatcg atttatg
//
LOCUS       DADQCX010000156         4034 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.162, whole genome shotgun sequence.
ACCESSION   DADQCX010000156 DADQCX010000000
VERSION     DADQCX010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.162"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            79..234
                     /locus_tag="J8R83_002701"
                     /pseudo
     CDS             79..234
                     /locus_tag="J8R83_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
     gene            253..1530
                     /locus_tag="J8R83_002702"
     CDS             253..1530
                     /locus_tag="J8R83_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575800.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="J8R83_002703"
     CDS             1540..2196
                     /locus_tag="J8R83_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9575801.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="J8R83_002704"
     CDS             2196..3572
                     /locus_tag="J8R83_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9575802.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="J8R83_002705"
     CDS             3702..>4034
                     /locus_tag="J8R83_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAZ9575803.1"
                     /translation="MARKKGNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1611 a          439 c          705 g         1279 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaattaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaggaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DADQCX010000157         3858 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.163, whole genome shotgun sequence.
ACCESSION   DADQCX010000157 DADQCX010000000
VERSION     DADQCX010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.163"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..101)
                     /locus_tag="J8R83_002706"
     CDS             complement(<1..101)
                     /locus_tag="J8R83_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAZ9575804.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQE"
     gene            176..454
                     /locus_tag="J8R83_002707"
                     /pseudo
     CDS             176..454
                     /locus_tag="J8R83_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
     gene            597..818
                     /locus_tag="J8R83_002708"
     CDS             597..818
                     /locus_tag="J8R83_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575805.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            834..1676
                     /locus_tag="J8R83_002709"
     CDS             834..1676
                     /locus_tag="J8R83_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575806.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1739..3541
                     /locus_tag="J8R83_002710"
     CDS             1739..3541
                     /locus_tag="J8R83_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAZ9575807.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3600..>3858)
                     /locus_tag="J8R83_002711"
     CDS             complement(3600..>3858)
                     /locus_tag="J8R83_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAZ9575808.1"
                     /translation="GITISIPPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1366 a          559 c          772 g         1161 t
ORIGIN      
        1 atttcttgaa cttcacgata gctaaggtta taacgaagat agtagcccac ggctacaata
       61 atcacatcct gctgaaattg ctttccttta aaatgattca tcgtcattcc tcctgctatc
      121 tttttctatt attctacctt atttgatagt agatttaaaa ctttgcaaca gaaccaaaga
      181 actcatcaag ctggctaata agggtcaaga ttatgaacat ctagcagatg agattgatga
      241 gctgagagac aagcgacagc tccttttagt agaagatgcc tccctcagtg gcgagaacga
      301 gcgaatcaat gagctgattg aatttatccg caagaacaaa ttccgtacct tagagtacga
      361 tgataagctt gtaaggaaga taatccagag cgttacagtc tatgaagaac acttcgtcat
      421 atccttcaaa tctggcatcg aaatggaaat atgaaaacca gaagtaaata gcctatgatt
      481 ctacagtaga gtcgtgggtt ttcttttgct tgctgattat aataatattt taataactat
      541 tgttattata aaccaaatga tttataatat tcttagcgta aacttggagg tgctgtatga
      601 ctacggcaga aatgattaaa gaactgtgtg agcaaatgaa tataagtgtt tccgaacttg
      661 ctagacgtat tggacagact ccacagaatt tcaataagaa attacaacga gaaacggtaa
      721 ccttagatga gttgaaagcg attgctgatg tgctaggtgt caagtttgtg caggctttta
      781 tattgcctga tggcaatgaa ataaagatag gtaattagga ggtgtaattt gtattgaaaa
      841 tcataacaat aaatgatgtt gagtatgctg tatttgctgc taatgaaggt acttccaaac
      901 cacaacctca tatcatagaa acgaaatctg gtactattcc agaaggaaaa caactgagtt
      961 tattaaaaga atatcttaag cagaatgata tttccccaat aaaaggagca acaacatatt
     1021 ggtgcattga caaggttctt aagcttgatt caagtaaaga aaaaactata agtgaaacaa
     1081 tccataaaca aaaatactta tctttaactg aagaaaatat tgagaaacag cataagtttg
     1141 taggtgcaag ctctaattat gggaaagaag gtctaataat acatgatgtt ttgaatgcat
     1201 ttcctcttca taatgattta aatactattg cgatgaagat tgcggtaatt gatgtaacaa
     1261 attcaacaca tctttctcaa tataagagca ggttgtctct atatgatttg gctaaagtaa
     1321 ttctggagat tccaaatttt gatgatcggt tggcaaaagg agatcctcag ttgataaata
     1381 ttatcgcaag gaacattggt gcagttaata tgttctcatt tgcatccaag tactgtacat
     1441 atcataatgt ggaagtgtgt gggagagatg attactccat ctttgatggt atcgttaaaa
     1501 atactcttcc acactatatc caaggactaa ctacgaataa gattgatacg tggcgaagaa
     1561 gttttgatta cgaggcattt aacgaatgtg ttggaaaact acttgatgaa aataatatac
     1621 atattccttt tagaagaaga aagttagatc acttcttgtg gtatgcgaat aggtagaata
     1681 taagaaaaag gcatcgtaaa agtgattctg gataaaatta atgggggagg aaataatagt
     1741 gggattattt gattttctaa agaaaaaaca aggaaaggtt agtaaacacg ttgattatca
     1801 actggcttct agtctatttc gtactggtaa agtttttgct gaaaaattgg aagtggacat
     1861 atcaaatgta gatgagtttc gtaaaacttt tatcgctttt gatgtggaaa caactggcct
     1921 aaattcttct tcagatagaa ttgtagagat tggtgcggtg ctatttaaag aaggagttcc
     1981 aattcaatca ttcggaactc ttgtcaatcc aaaagttaga attgcagcct cagcttcggc
     2041 aataaataat ataactaatg aaatgctaaa ctctgctcca aatgagcagg aagtttaccc
     2101 ccagttggta gaatttttag gagatgcact agatggaaaa atcactatgt gtgcacacaa
     2161 tgcaagtttc gattttggat ttttaagtaa cacattttct agacttgggt atgatgctaa
     2221 aattaagtat gttgatactc tgagtctctc tagaaaacat ataaaaggca ttgtaaatca
     2281 taagcaagag actgtagcgg aatatttcgg attaataaat gacactgccc atagagcgga
     2341 atcagatgca gatatatgcg gaaagatttt ttggggtgtt ttagatatta ttgaggagtc
     2401 gttggaagaa caaaaaaagc aaatagaaaa gatgactcca gacataaaag aacttgaagc
     2461 ttgtgctttt attcaagata ttattgagaa aaaaggatgc gacaccagtt ggatcaggta
     2521 tcgaaaaaac agtaataatt atgtcgatgt aacttgtcta tatacattct taaagtttaa
     2581 gtttgctaag aagggaaatt acatcattat tagaaaagat gctacaaatg gaattgattt
     2641 acctatagaa ccttgtactg taagtgaagg cggtacaaca aatgtgcgag tctattttcg
     2701 tagccccttt gacttaacgc ctctttcaaa ttatattttc agtgcttata gcgattgtta
     2761 taattctatg aatgaatata tgagtgttag taattacact aaaaaagaag cagagcaaag
     2821 ccttagtatg ctgaaatcta tttcaaaatc agcgatgaaa gagttattat tcgatgcaaa
     2881 aaatcgtgga tatgatgaga ctgaagttaa cctaaatatt gaaaaagtga tatctagaga
     2941 agatgtaatt attaacgggt tgcataatcg agtttcatta aacaagatac gaaatatagg
     3001 gaattgggag aaaggatttg atgcaggtta tccatattgg gaacgtggag aaactgctag
     3061 gaaaaatggc aaagtagatg aagctattgc actttttgat aaagctcgat ataacggcta
     3121 tgatgctcct gcgctatatg attcttatgc taaagcttat cgaaaaatta aggattacga
     3181 taatgaaatt ctcattcttg atgaaggaat tatgcgtaaa acacggcacg atgttggtac
     3241 tttagaggct cgtagggata aggcaattaa gctattattt gctaaacaag aggcagagcg
     3301 gatagctaag gaaaaatctg attttctaaa agcgaacaaa aaagaggatg cgattagtga
     3361 gcctagcaag aagcgtggaa gacagattat tcaaatgact gatgatggaa caataataaa
     3421 agaattcgat actatagctt ctgctgtaaa agaagttggc gttaactcaa aaagtattag
     3481 ggatgctgca aatggagttc aaaaacatgc tggaggatac tactggaaat acaaagatta
     3541 gcagataatc taagataacc taggatcttc ttaatagata cccgtggtgc tagttaattt
     3601 taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg acttaataga
     3661 acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac agaacgtgag
     3721 ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtcccaac tgtttttctt
     3781 tgttttccaa gtaagctgtg gtctagtttt tctgatttat ccatgttttt acgtggcgga
     3841 atggatatag taatgccc
//
LOCUS       DADQCX010000158         3848 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.164, whole genome shotgun sequence.
ACCESSION   DADQCX010000158 DADQCX010000000
VERSION     DADQCX010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.164"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(692..3841)
                     /locus_tag="J8R83_002712"
     CDS             complement(692..3841)
                     /locus_tag="J8R83_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAZ9575809.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1070 a          795 c          632 g         1351 t
ORIGIN      
        1 tgttattttg atattctaaa tcatttttta ttggattatt cccttgttcg atatagaccc
       61 aaattgatct atcaataatt atcaaactga gtcatataga gacaaaaatt tcaaaaatga
      121 cctgttaaat ggtcatcgaa tatcatttaa aatcaatacg acggagtcag acacggagtc
      181 aaaacaagcc cgctgagagt aaaaaatata tacagtccca taggtaaagt gccacaggac
      241 tgtatatttt tttatttgag attacctgaa atgattccat ttacttttta tctcattttt
      301 tcctactagt tagtatcaaa tactctccta ttttctcaat aaactatttt gggttacatg
      361 gtatctgaaa cagctaaaac cttgtcatta cagcaaaaaa tcactttatc tccgtttcat
      421 ttcagataca tttcacttaa gcggattcca aaaaaacaaa agaaaaagga acccctagtt
      481 agcctatgct ttttattggt tcctctcaaa acacggtcat ataacaacgg ggtggggtaa
      541 atgaatgaaa aaggtggagg aaacattatt caatagctgt cttaaatact tcgttataaa
      601 atgtgaacaa ataaaagaca tctatcccta ttttctacac ttccacttta ctaccatctt
      661 tgaatcgtac aattttctta actcttctcg tttacctcaa ttcattttca agtggaatca
      721 gctcatcatc taacatttta cgccatgctc gcttcatttc ttgtgggtat ttaaatggct
      781 tcgcttctgg atggttggct ttatatcctt cgtaatcctt actgttgata attgctttca
      841 tattaggaat tggatcttca cctggcatat attgcagatt agaagcatgt aattctttct
      901 cagaaacaaa ccactcattg gaaaagacat gaatcaaatc atcactcgct tgtgtaaaat
      961 agcgacgttt aatgacaaag atatcttcat tactatctaa agtccccaca tcaaacgcat
     1021 ttaaaatttg tcggtaaact tctttgactc cttctgtttt attcaattta gccaaagctt
     1081 tttcaatttc ttctcgtgca tctgaactat tcgccgcata agttcctagt aattgatcaa
     1141 tataagtaga atcaatatca tacaacttcg tggtattttc actataaaat tcgatcgtgg
     1201 aaaaatcttc tccctctttt tctggttctt cctctattaa tgaacccttc acggtctcgt
     1261 acacgccaat ttgttcttcc aaaagttgaa tttgattgtt caaggttgaa gatttcacca
     1321 tgtcatcatt gtaatcgtca taagtcacta acgattcata agcacgattc aattcttgga
     1381 atgctttgac gtactcgata cggatttcaa gtggcgtatg ttcatcaatg gattccatgg
     1441 atgaaacctc ttttaactta ccatatgctt gcttgaatct ttttttggat tcctgataac
     1501 ttggataaat caaacccgat tcttcttttg cttctgaata cagttttgtc gcatcctcga
     1561 cattcttctc cattgtggct ggctttcgga aagtaacaat tagtcctttt gttttttctg
     1621 gatacgtacg gttcgtacgt gaaaaagctt ggatcaatcc tgcatactct agattacgat
     1681 ccacaaatag ggtttgaatc gtaggtgcgt caaaacctgt caatagacga tccactacga
     1741 tcactaaatc aatttgtttc ccaaattgtt tgaattccgc tctttttcgt gccaaacgat
     1801 tattgatgtc tccgttataa cgctcaatgt ctgctaatga ccaggaagta tcataatact
     1861 gattatattc ctcaataatt ttttgcattt cttcttgttg gacacttgaa tctcggctgt
     1921 tttcttctaa tgaataggta atagcgattc gtggaaaatc aggatcctcc atcgttcttc
     1981 cttcacgaat gggctgatta ggaaactctt ttgttaacca gtcaggttct ttcgtcattt
     2041 ctttgatcgc tcgataatac tttttggcca tgtcaatgga actcgtggtt aagatcgcag
     2101 acttcgttgg acggccattt cgaaaatcaa attttgtata ggcattgtct ggacggaaca
     2161 ttttatgaat gactttttgg atatgttcat ctgcttcaaa aacagtaggg tccaaataac
     2221 tttctttttt gacaggctcc atttgatcaa tcatacgatt gatctgttcc ggtgaatact
     2281 ctgcatatgt ttctacttct tttaatttcc gatagatttt attctctaat gaagtcggct
     2341 ccacggtgtt ttcatgctct acttgaaatc ctaaaaccga gccatcttct aatgcattct
     2401 tgatggtata ggtatgcaag acctctccat actgatcatg ggtcgtacgt gccaattgcc
     2461 ctttggcttg tttccgattc tcagggaaaa tcggtgtacc tgtaaagcca aaccaagtgg
     2521 atttcggaaa catttttttg atttcttcca tattttcagc acttaacgct cgatgacact
     2581 catctactac aaacacgata tgttgcccca ttaatttttg gaagcgattg gttccttttt
     2641 tctcttcttg tttttttgca tatttcaacg ccgcatctag cttttgacgg gttgtaataa
     2701 tcacaacatt tgcattggca tctgccaaca gagtttcact taactctttg gcacttcctg
     2761 ttcccacgat caagctattc gctttggcgt tcccggaaga aatcccagta ttaaattccg
     2821 aagcaaattt cgtaaactct gtggtggttt gattatctaa atctttgcgg tccactaaca
     2881 tgatcgtccg atcgatcccc gattttcgtg ctaaaagctt agtagataca aaactagtca
     2941 acgtttttcc tgaaccagtc gcatgccaca catatcctga ttgatgttta tttgcagcaa
     3001 taaacaaggc ttgaatcgca tgtacttgat aaggatgtaa caccatgagg attttattgt
     3061 cttgatcttc actgacaatc gtataatccg caatcaagcg atgagcatcc gggatattta
     3121 gcacttgttt gcaaaactca tataagtttt ctaccttttt attatctttc gttcgccaac
     3181 taaataaaaa cttaggatgc aaatcctttg gtaaggcatt tgcaaaatac cgagtggttt
     3241 gttcattgga aaccacaaac aactgtaagg tcgaaaagat attgttccga aacatacctt
     3301 cttctgcata ttttttgatt tggttaaacg cctgataaaa actatctttt gcggttactt
     3361 gtttcagctc gatttggaca atcggtaatc cattgatcag taaggtgacg tcaaaacgtc
     3421 gatcccgtgc ttctatgtta cttccacgtt ttgcaatttg atggaccact tcataggtag
     3481 agattcctcc accaatgtct tgattagaat aaagaatgag cgagacagaa cccagttgcg
     3541 gatcttcccg ttcaatcgtg atccgagcca ttccattttc accttttaac catttcgcag
     3601 catcaaaggg ggttttcgtt cgtagtaaca attctgtttt gatcgtttca aattctttat
     3661 cggtcaaagg aaaatcattc agttctgctt gattatttga gatgattttt tggcgtaaat
     3721 tgacccaaag atcttcttct gattttagat cgggacgata cgtccactga ttatgccctt
     3781 cccccaatac acggatcaac tgttcttcga cttccgcttc ctcacggtga ctaattttca
     3841 tttatctt
//
LOCUS       DADQCX010000159         3794 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.165, whole genome shotgun sequence.
ACCESSION   DADQCX010000159 DADQCX010000000
VERSION     DADQCX010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.165"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            7..981
                     /locus_tag="J8R83_002713"
     CDS             7..981
                     /locus_tag="J8R83_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9575810.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKKQVRE
                     YLIDNFFFIIKNKRLTFQRKISMLLLTFGIAAYKIPVKYQYKKVKAVN"
     gene            1052..2539
                     /locus_tag="J8R83_002714"
     CDS             1052..2539
                     /locus_tag="J8R83_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAZ9575811.1"
                     /translation="MFIYILRIVIQFVGRSFFIYFLGAKYLGLNGLFTNILSFLSLAE
                     LGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIGIVGVLIIPLLPLFIKN
                     STDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAINDFAFLFFMNIVQVIA
                     LYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVVSLDKQTKDEVKKNVIG
                     NMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQNLCKQITNSITASVGN
                     FAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISLWVGAKYMLPMSTTILI
                     VLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSLLLLIVFDMGINGVLIG
                     TIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIELIISAIVVFLLNEYLANGG
                     STFLQFITKTLITIVTTSILYLLLYFRREEFTFIKKILFRYILKK"
     gene            2596..3711
                     /locus_tag="J8R83_002715"
     CDS             2596..3711
                     /locus_tag="J8R83_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9575812.1"
                     /translation="MGGASIVASKIAKGLIDSGHEVFFVSYLESEKPQVESKYYDLYE
                     KKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSV
                     LFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIVCLSQDTKEK
                     LSLYNNHIKVIYNPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
BASE COUNT         1400 a          406 c          630 g         1358 t
ORIGIN      
        1 actaaaatgt gcagaataag tataatagtt ccagtttata atgttgaaaa atatttaaaa
       61 aagtgtgtcg attcaattct aggccaaaca tttaccgatt ttgaattatt attaattgat
      121 gatggttcta cagataattc aggaagtata tgcgatgaac ttgcgaaaac agacaaccga
      181 ataaaagtga tacataagga aaatgggggt ctaagtgatg ccagaaatat tggtattgag
      241 gtagcaaagg gagattttat tgggtttata gatagtgatg attacattga tgaagatatg
      301 tatgcatttt tatataacaa tatattgaaa tatgatgcag agttatcaat gtgtggtatt
      361 tatgacgtcc ataagaataa agaaattaaa aagttaactc ctttttctca attggttact
      421 aaatctgaag caattgaatt agtattagat ggtaagctag ttgttgctaa tgcagtaagc
      481 aagctatata aaaaagaatt atttgagaat gtgagatatc caaaaggaaa aattgctgaa
      541 gacgcagcag taatactgaa aattatcaat cagtgtaata aaatccatgt tgatacttct
      601 caaaaatatt attattatca tcgtggagat agtattacta gtaaaaaatt tacaaaaaaa
      661 gattttgata taattgatgt atggaatgag aatgaaaaat ggattattaa aaattatcct
      721 caaatgtacg ataaagtaca tactagagtt tgttgggctt actttgttgt gttagataaa
      781 ttagttttaa ctgaagaaaa aggactgtat caagaaaaaa aacaagtaag agagtattta
      841 attgataatt tcttttttat tataaaaaat aaacgattaa cttttcaaag aaaaatatct
      901 atgttattgc ttacttttgg aattgctgcg tataaaatac cggttaaata tcagtataag
      961 aaagtaaagg ctgttaatta atgctttagt taggatgaat tagatgaaaa aaagcaggtt
     1021 agagtattct ttaataaatt cttctatatc aatgtttata tatattttaa ggatagtaat
     1081 acaatttgta ggtagaagtt tttttattta tttcttagga gcgaaatatt taggattaaa
     1141 tggtttattt acaaatatac ttagtttctt gtcgttggct gaactaggca taggctcttc
     1201 tattatttat tccctataca aaccattagc ccaaaaggat gaaagtaaag taaaggcttt
     1261 aatgaatttg tataagaaga catatgaatt tattggtatt tttatcggca tagtaggagt
     1321 attgattatt ccgctgttac ctctatttat taaaaatagc acagacatac cacatatgta
     1381 tcgatattat gtattatttt tattaaattc agttcttagt tattttttca cgtataaaag
     1441 atcacttgca atagcagatc aaaaaaatta tctggttgcg attaatgatt ttgccttttt
     1501 attctttatg aacattgtac aagtaattgc tttgtacttt tattctaatt ttactctatt
     1561 tctaatagtg cagattttgt ttactctatt ttctaatata aatatttcca gaacagttga
     1621 caagagatat tcatatttaa aagagaaaga tgtagtttct ctagataagc aaacaaaaga
     1681 tgaagtaaag aaaaatgtca taggtaatat gtcctcaaaa ataggcgggg ttattgtaat
     1741 ggggacagat aatatattaa tttctacatt tgttaattta acagctgtag gaatttattc
     1801 taactattca ttgattgtca caagtgtgca aaatttatgt aagcaaatta ctaattctat
     1861 cacggcaagt gtaggaaatt ttgctgtatc aaataaaaaa aaggattcat ttgagctatt
     1921 taaaaaacat ttttttatca accactcact aatctttttt tcttctatat tgttattgac
     1981 tttaatgaat cccttcatta gcttgtgggt aggagccaaa tacatgctac ctatgtcaac
     2041 gactatttta attgttttaa attatagtgt acaggtttat agaaatacat ccttcgtttt
     2101 tatagagtca tttggtttat attggtctca acggaaaaag cctataattg aagcaggtgt
     2161 aaacttgtta ttatctttgc ttttgttaat agtttttgat atgggaatca atggagtact
     2221 tatagggact atcggatcgt ctctaggatt tgtgatttgg tatgaagcat ttatcatata
     2281 taaaacggta tttgagaaac gttttattca tttcttttta actttctggc gaagttttat
     2341 agaattaata atttcggcaa tagtcgtttt tctattaaat gaatatttag caaatggagg
     2401 cagtacgttc cttcaattta taactaaaac cttaataact atagtaacaa catcgatatt
     2461 atatttgtta ttatatttta gaagagaaga atttacattt atcaaaaaaa ttctttttag
     2521 gtatatttta aaaaaatagc tttctataaa ggagtgtttt atttgaaaat agctatacta
     2581 tctccagctt tctcaatggg aggagctagt atcgtggcct caaaaattgc aaaaggatta
     2641 atagatagtg gccatgaagt tttttttgtt tcttacttag aaagtgaaaa accacaagta
     2701 gaatctaagt attatgattt atacgaaaaa aaaatttttt tatttaaaaa tttttctcga
     2761 tttcataaga tattagagta tagattgttt ggaggctttg ttcctagtag atatataaaa
     2821 aaagaaaaag aacaactaaa aaaagttcta aagaaagaaa aacctgatgt catcatattc
     2881 aatactttta tacctagtgt actattctcc gaattcctaa agtatgaatt tccaacagtg
     2941 aaattaatta cttggatgca ctctgatcct gattacagct taaatcatat tgctaaattt
     3001 tataaaaaag aatatagaaa aagttttgaa cgcgtggatt ccattgtttg tctttcgcaa
     3061 gatacaaaag aaaaactttc attatacaat aaccatatta aagttattta taacccattg
     3121 acattaagcg gctctagttt aataagtaac cttgataaaa aaattatttc atttactgcc
     3181 agatacgata taaatattaa agggtttgat tatttatgtg aagtagctaa aaacttacct
     3241 gttggatggg ctataaggat tgctggagat ggtacagaag aagaacgtaa agagctgaaa
     3301 agattaattg agaaaaatgg tgtgttagat aaaattattt gcgcaggtgc attatttgga
     3361 gatgaattaa tcaatcatta tatagaaagt tctattttca tatctacttc tagaagtgag
     3421 ggactaccat tagtgttgat agaagcaatg acttatggat tacctgtaat aagttttgat
     3481 catggtggtg ctaaggaaat attacaagat ggaaattatg gaattttaat taagaatttt
     3541 gacgtacaag atatgaataa tgagatagaa aaattgtcta ataatcgttt acttatggaa
     3601 aaatatcaaa aattctcttt agaaagagct aaggatttta atgaaaaaaa aataattggt
     3661 gaatggcaaa cattgttaaa tgaattagga aatgaggatg ttagaaattg aggacttcga
     3721 ttaaaaattt taatttatgg aaagaatggt atctatatat attttttata gggatgatta
     3781 ttcgtgcaat aaat
//
LOCUS       DADQCX010000160         3476 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.167, whole genome shotgun sequence.
ACCESSION   DADQCX010000160 DADQCX010000000
VERSION     DADQCX010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.167"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..203
                     /locus_tag="J8R83_002716"
     CDS             <1..203
                     /locus_tag="J8R83_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9575813.1"
                     /translation="PLNENSNGILRRNGLPKSMDFREVNQTFISSVSNQRNHIPRKSL
                     NYRTPIEIFLSYVQEAFYSSLI"
     gene            697..984
                     /locus_tag="J8R83_002717"
     CDS             697..984
                     /locus_tag="J8R83_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575814.1"
                     /translation="MEIKEIKVRGINKKYVQEIDHRCVELTEQTGQKWSRNDYLKLLI
                     ENDFERPLMDYKKDQFDRLLEKFTDVQLHNTKVLEAYTNEVKNLIEILIAH"
     gene            1002..1424
                     /locus_tag="J8R83_002718"
     CDS             1002..1424
                     /locus_tag="J8R83_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575815.1"
                     /translation="MVKAIEKHITFYEAHDEVLKHIMETQPTVKNYSEAIRFLCMNYD
                     PEIEKNNNMTNAKLNAMGKEISILIEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
     gene            1444..3036
                     /locus_tag="J8R83_002719"
     CDS             1444..3036
                     /locus_tag="J8R83_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575816.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQNSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQIEQERQ"
     gene            3292..>3476
                     /locus_tag="J8R83_002720"
     CDS             3292..>3476
                     /locus_tag="J8R83_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575817.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         1385 a          537 c          664 g          890 t
ORIGIN      
        1 gcccattaaa cgagaattct aacgggattc tgcgtcgtaa tggactgccg aaatcaatgg
       61 attttagaga agtgaatcag acatttattt ccagtgtcag caatcaacgt aatcatattc
      121 caagaaaatc attgaattac agaacaccaa tcgaaatatt tttgagctat gtacaagaag
      181 cattttattc tagcttaatt tgacaaatca tatgaaaaaa gtatataaaa aatgtttatg
      241 gatcagctat atcaccctag gtatagctgt taaagagatg ggagaaaaca ttaaccacga
      301 ttctaacaca aacatcaagc acataaaaca tttaacactc ctcctttctg gctgaagatt
      361 tcaaccaaac aggaagacag cgtatcaatt atagcataca ctttttctta aattcatttt
      421 tcatatgaca aaatatttcc ttctaatcga caaagttaga aggatttttt attgtctaaa
      481 tacacaaata accttaattt ttaaagagca taaggaaacg tgggaacact ttttaaaaaa
      541 agtgttccaa taggctgtgc ctattacgtt tctctaaaac aaaagtgggt acaaaatatt
      601 cgatttatgg atagtgtatg gatagtaaaa cagctataca tggatagcat atggatagac
      661 tccatagact atccatactt ttttcggagg gtgaaaatgg aaattaaaga gattaaagta
      721 agaggtatta ataaaaaata tgttcaagaa attgatcata gatgcgtaga attaacagaa
      781 caaactggtc aaaaatggag tcgaaatgat tatctaaaac tattgattga aaacgacttt
      841 gaacgtcctt taatggacta caagaaagat caatttgatc gtttattgga aaaatttaca
      901 gatgttcagc tgcataatac aaaagttttg gaagcataca cgaacgaggt caagaactta
      961 attgaaatat taatcgcaca ttaggaagga gataatgttc tatggttaaa gcgatagaaa
     1021 agcatattac attttatgaa gcgcacgatg aagttttaaa acatattatg gaaactcagc
     1081 ctacggtaaa aaactattct gaagccattc gatttttatg tatgaattac gatccagaaa
     1141 ttgaaaaaaa taataatatg acgaacgcaa agttgaacgc aatgggaaag gaaatttcta
     1201 ttttaataga aatggtttca gagtttgcgg atcttcattt gaaagataca ggaatattaa
     1261 ttggtacaaa ttcaactgtc tatcaagaag caaaagagcg tgtggaaggg aaaataaaag
     1321 cgaatcaaac gaagaagtat tctcctaaaa tcaagaaatc aataaatgaa tctgttcatg
     1381 ccagagtaga cccgtttgat ccaacaaagt ttttaaaaag ataaaaagta gaaggggaat
     1441 atgatgaata aatcgcctgc agtcattctc acttgtcaat ttaccttgcc caataaaaaa
     1501 tctttttcaa catacattga ttatatgaca agagaaaaag cgctggaaga aatggaacga
     1561 cgtacgcctg aagaagaaca ggaactgcaa cgaatcaaga atgctttaga ggatttttat
     1621 attcctgaag gagaaacttt ttcggagagt aagacggata aagaattcag cgaaacgtcg
     1681 aatgaagctc aatctttgat gggaaatgga atcaactttg acaagttaga ggaacaagat
     1741 tttaccaaat atctttctta tatgacccgt cactatgcgt tagaacaaaa gaaagaactg
     1801 acgcaaagtg aacaaaaaga ataccaacgc ttgaaccaag caataaaaaa atatcaaaca
     1861 gagccacaca aaaaagcttc aggaaacctt cctggagttt tttctatggc ttcagacgaa
     1921 gtgaaaggaa gtgatctgaa ggagattaag caaatcttcc aaagaggaca acaaaaaggc
     1981 tcaatcattt atcaagatgt tgtctctcat gataattcgt atcttgaaaa aataggattg
     2041 tacgatccca aaacagatac tttagatgaa gaaggattaa aagcagctgg aagaaaaatg
     2101 atggagacat tattcgagaa agagcaactg aacgaaacag gctactggat ggcaacgatt
     2161 caccgtaata ccaaacatat ccatattcat tttgcagttg ttgaaaaaga aaatacgcgt
     2221 aaaccttaca cggaggttga aaatggtgtg agttatatcg taccgaaagg taagagaaga
     2281 caagcaacat tagacgcaat gaagaccaat tatgtacatg agttagaacg tttttcttat
     2341 gaaaaggatc gaatgattgg tatggagaaa cgaaatttat tgacgcggaa aagtgatttg
     2401 cgtaacacct taacaaaagt ggtaaaagag ccagcgcgtt acgatcgaca cgcaatgaac
     2461 ttattaaatg aagtatataa aaccctacct gacaaacgtt cggaatggca ttatggggat
     2521 gaaaaacgaa ccaaactttc accatacaca agagagaaac tcgatgagtt aaccaaatat
     2581 gttttaacaa aagaacctga atatcaagaa tatatacaga tttcaaaagc attgaaagaa
     2641 gaagcaaaaa gtctttatgg ggaaagcaaa agagaatcaa aggatgcaga aaaaaatgct
     2701 ctctttgatt tgaaaaagcg cacaggaaat gccattctaa cagaactgaa gaaacagaat
     2761 agtcaaataa aacctttaat agaaagtatg gatcagatgc aatctattta caatgaacga
     2821 tcctttcgaa cgcttaaaca gttaccaacg aatgaataca aatatagtta cgaagaattc
     2881 atgaagcgca ggaaacaatt ccaacaaaga gttgtcacgc aacggagttt gcgtcaatta
     2941 aatcgaacga ttaatgccca tgaagaaaaa taccacgcaa gtaaagccta cgaagagcaa
     3001 caacgaagaa tccaaataga acaagaaaga cagtaaagac agtaaagtta gcgccttatt
     3061 atactacttg ggaaatgaat gaagagggga tcaataactt cccgtgtaaa agcattgaag
     3121 agtctatttc actcacagaa tgttagttgt taagtgaata aaagaagtaa aagagtcctg
     3181 aacgtaattg tccaggactc tttttttcaa tgaattgttt tccgccaatt caatgagtgg
     3241 tgcgatttgc gactacatta tatcaaaaga aagagaaggg aggaagaaga aatggcttat
     3301 tcaacgattg gagttgttgt tgaaaaaagc agagacaatc tcgtttttgt gacagaaatt
     3361 caaacaggca gagcttttgt cgtcacagac aaagcggcaa aagcgtatca aaatggcgat
     3421 attttaacgt taaatctgac tacgaagacg ttcgtcgatg cggcagaaga ttatcc
//
LOCUS       DADQCX010000161         3310 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.168, whole genome shotgun sequence.
ACCESSION   DADQCX010000161 DADQCX010000000
VERSION     DADQCX010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.168"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(551..2164)
                     /locus_tag="J8R83_002721"
     CDS             complement(551..2164)
                     /locus_tag="J8R83_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAZ9575818.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2305..3213)
                     /locus_tag="J8R83_002722"
     CDS             complement(2305..3213)
                     /locus_tag="J8R83_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575819.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1078 a          564 c          577 g         1091 t
ORIGIN      
        1 taaataaata ggaacaaaaa aattaaatta tttaatacac acattaggga tcattcattg
       61 aaggattaga agacaacgag gatggcgaaa aatatgatta caatagaaaa gtcgttctaa
      121 accaatcagt tcctagtatc acacaacgca agccagtcga tttggtgaga ttagaggagt
      181 gaaagcaaac tttattatat aagaaaaaat attcgaaagg gatgctagtt taggtactag
      241 tgctgataga ttaatatgat gcctcgtaat attaggcgta gttactctag agacatcact
      301 atggactatg atttgtctca gagtcacaac atgttttttt atgaaaagaa acagctaaaa
      361 taattaaatt gcgcaatgtt taaactttct taaactataa cctaataaat gtgaagaaat
      421 aatgcacaat ttcttcacat ttatcttcta ttctatatac ataccaacca acaaccctat
      481 atactttttc atttttactc ctcaagtaaa aataactcct agaccgcggc tacccaccgc
      541 ggtcgttttt ttattcttca atcaaaatcg ctttgatacc caaacctgcc aagattcggg
      601 cagaagtata agtattcaat cctcttctga aagtaatgta aactttttta tcttttggga
      661 tttcattgat tcgatctcgt aactcattca ttggaatatt ttttgttgcc gagatactgc
      721 cagaaggtgc tttattaggt tcacgtatat ctaaaaagaa cgcttctttc aaatcgtttt
      781 cgggtatatc acttgctttg atcgtttcta cgatattcgt catttgattg attgcgacat
      841 aaccagctat attcaacggg tcacgggtag tagaatacgg tggagagtaa ggcaactcca
      901 aatcaggcaa atcaaagact gtcaagtttc cggtgattgc tacagaaagt tctcccatcc
      961 gtttatcgac acctttttct ccaaatgctt gtccacctaa aatacgaccg ctatctgcat
     1021 caaaaatcag ctttagattt aatcttgtag cttctggata gaaataggca tggtcaaagg
     1081 gagtgataaa aacagtttta taatttgtta tgcctgatgc ttttaattca tgttctgtca
     1141 ttcccgcata acttgctgta tgatcaaaga tttttgcgac acctgcacca atatatccgc
     1201 gatagcgcat aggcgtacca tttaaaatat ctgccagcat atgtccttga cgattggccg
     1261 cactggaaag catactttgg atcggctgac cagtcactac actagtcgtt tcgataatat
     1321 cgccaatcgc atagatgtcc ggcagattgg tttgtaactg gtcatcaaca atgatctgac
     1381 ctgtatctga taattgtatg ccggttgctt tcaccacttc attcttcgga gaaacaccaa
     1441 cagcaaaaat tagcatatca gcagaaagga cggagccatc tgataatact atttctcgac
     1501 ctttatcacg gatctcagta actcttgttt ctaaatgaac ggctaatcct tctttcagca
     1561 atttgtcata aactaaatta gcaatttctg gatcataagg gaaagcgact tgtggcaatt
     1621 gatcgattaa agtcacgtct aagccgcgat gcttgaaatt ctcagctaat tccagaccca
     1681 taacacctgc accaagaatg acgacatgtt gtggattttt ttcttcaagg aacgatttga
     1741 ttcgatccgc atccgtcaca ctacggagga caaagccgtt ttctgcttca aaaactccgg
     1801 gaatatccgg ataatctggt ctagcaccag aagagatgat caacttatcg taatctgttt
     1861 ttatttcttc atttgtggat aggtctttaa ctgttaatcg cttagtagaa ggatcgattg
     1921 ctgttacttc gtgtttagta aagacatcga tgttgttttt tgttttcaat atttctggtg
     1981 tacgttcgat cagcgagtca cggtcagtga tcacacctcc taaataataa ggcaaagcac
     2041 aacttgcata agaaatattt tctccgcgtt catagataat gatttcgtgc gcttcattca
     2101 atcgacggaa acgagtggca aatgaaggac cgccagctac accgccaatg acaacaactt
     2161 tcataaaaac atctcctttt ctacgttgat cgtactatgt tatggtaaaa aacagcaaat
     2221 aattgtgccg gaaaattatt gtttattttg aatagacaga aaatatagag aaataatttg
     2281 tggataaaac ctaaaaattt ttttctattt taaggataga taatactttg aaggggataa
     2341 ccctgtatat tttttaaaag ctgaagaaaa atgatggatc gaatgaaatc ctaatatatc
     2401 tgcaatttct gtataggtta attcattttc tagcacgaga cgttttgctt tttccatttt
     2461 tagttcttta aaatagctaa taacactttt tccattcact tttctaaaat gtttttttaa
     2521 gctggctgga ctgataaaaa aaatttgggc taattgttca agcaaaaaat tttctgaaag
     2581 atgttcttct aaatatcgta tgattggatc aactaattca tctgaataaa gaatatgctt
     2641 ttttttagga atgactttct catttgaagg tattgtcaat aaagcaagtt cctgttgata
     2701 atgccttggt aaggaagaca attgaatttt ttgcagacaa taagtaacta ataaggaaag
     2761 caaatgaatg ctcatctgtt ggcatagtat gaaaaaagaa ttgatttcct gatcatagga
     2821 aatagctggc ttactatgtt ttagataatc aattttgaac tgttcatttt tcagaaaagt
     2881 aatgatagat gttatttctt gatctataga aaaagattgt cccgtaatat gtgctaataa
     2941 ttgctcatca aaataaaact ggataatgat aaaagtttgt gtttcctttt gagtagaaaa
     3001 gatttggact tcttgctgtt tatcaatgaa taaaagggaa ggattatcta gttctataga
     3061 tttatgtgca aattcagcat ataaattagc gctttcattt attagtagtc gaaaataggg
     3121 agcagcagat aaatgaagat gggtatctat ggaataggtt agtgtttttt tgacaagatt
     3181 ggaggattgg ttgtttgtta acaaaagaac cactttcctt tctcttttta tataaaaagc
     3241 tttctattta taattaatga ctattataac aaaaatgaaa agccaaaacg acaagtaaaa
     3301 tattttttta
//
LOCUS       DADQCX010000162         3279 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.169, whole genome shotgun sequence.
ACCESSION   DADQCX010000162 DADQCX010000000
VERSION     DADQCX010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.169"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2232)
                     /locus_tag="J8R83_002723"
     CDS             complement(<1..2232)
                     /locus_tag="J8R83_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575820.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="J8R83_002724"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="J8R83_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          897 a          732 c          535 g         1115 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctat
//
LOCUS       DADQCX010000163         3220 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.170, whole genome shotgun sequence.
ACCESSION   DADQCX010000163 DADQCX010000000
VERSION     DADQCX010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.170"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            50..1438
                     /locus_tag="J8R83_002725"
     CDS             50..1438
                     /locus_tag="J8R83_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HAZ9575821.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3220
                     /locus_tag="J8R83_002726"
     CDS             1776..>3220
                     /locus_tag="J8R83_002726"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAZ9575822.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1184 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaaga
//
LOCUS       DADQCX010000164         3058 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.171, whole genome shotgun sequence.
ACCESSION   DADQCX010000164 DADQCX010000000
VERSION     DADQCX010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.171"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            160..1014
                     /locus_tag="J8R83_002727"
     CDS             160..1014
                     /locus_tag="J8R83_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9575823.1"
                     /translation="MEKEELKILEELRRILNSKNEAIVILNNYFKGGVGKSKLSTMFA
                     YLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKNGNLASSIIHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMLERI
                     IQLENEKE"
     gene            1085..1300
                     /locus_tag="J8R83_002728"
     CDS             1085..1300
                     /locus_tag="J8R83_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAZ9575824.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDKALEEYIRKYLPDKL"
     gene            1317..1589
                     /locus_tag="J8R83_002729"
     CDS             1317..1589
                     /locus_tag="J8R83_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAZ9575825.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            1591..2454
                     /locus_tag="J8R83_002730"
     CDS             1591..2454
                     /locus_tag="J8R83_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAZ9575826.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAILEETQGNVIVIDNDTFKQQHPNFDELAKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSRLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMLQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGL"
BASE COUNT         1157 a          469 c          548 g          884 t
ORIGIN      
        1 tctttttcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg attcctaatg
      121 atacaatatt actatataaa aaaagaatgg ggcgtagtta tggagaagga agaactaaaa
      181 atacttgaag aattaagacg tattttaaac agtaaaaatg aagcaattgt tatcttaaac
      241 aattatttta aaggtggtgt tggaaagtca aaattatcga ctatgtttgc ttatttgaca
      301 gacaaattta atttaaaagt tttaatgatc gataaggact tacaagcaac attgacaaaa
      361 gacttagcaa aaacatttaa ggtagaattg ccacgtgtca atttttatga aggcttgaaa
      421 aatggaaact tggcttcttc tattattcat ttgactgata atttagactt gatccctggc
      481 acgtttgatt tgatgttact gccaaaatta actcgctcat ggacgtttga aaacgaaagt
      541 agattgcttg ctactctttt agcaccttta aaaagtgact atgatctcat tattattgat
      601 actgtaccaa cgccaagcgt ttatacaaat aatgcaatcg tggcaagtga ttacgttatg
      661 atccctttac aagcagaaga agaaagtaca aacaacattc aaaactatat ttcctatttg
      721 attgatttac aagaacagtt taaccctgga ctagatatga tcggttttgt tccttattta
      781 gttgatacgg acagcgcaac gataaaatca aacctggaag aactgtacaa agaacataaa
      841 gaggataatt tggttttccg aaatattatc aagcgaagta ataaagtaag tacctggtct
      901 aaaaacggca ttacagaaca caaaggctat gacaaaaaag ttttatctat gtatgagaac
      961 gtattttttg aaatgcttga gcgaatcatt caattagaaa acgaaaaaga atagaatcac
     1021 aaatcacttg tgatttgtga ttgttgatga taaaataaga ataagaagaa atagaaagaa
     1081 gtgagtgatt gtgggaaatt taggcgcaca aaaagcaaaa cgaaatgata caccaatcag
     1141 tgcaaaaaaa gatataatgg gagataagac ggttcgtgtt cgtgctgact tgcaccatat
     1201 cataaaaatc gaaacagcaa agaatggcgg aaacgtaaaa gaagttatgg ataaagcctt
     1261 agaagaatat attcggaaat atttacctga caaactttaa aaggagtgaa aatgaaatgg
     1321 cagttacata tgaaaaaaca tttgaaattg aaatcattaa tgagttatcg gcaagtgttt
     1381 ataatcgagt attaaactat gttttgaacc atgaattaaa taaaaatgac tctcaattat
     1441 tggaagtcaa tttattaaac caattaaagc ttgcaaaacg tgtaaatctt tttgattatt
     1501 ctttagaaga attacaagcc gttcatgagt attggcggtc aatgaatcgt tactcaaaac
     1561 aagttttgaa taaagagaaa gtggcttaat atggcaaata tagtcaattt tactgacaaa
     1621 caatttgaga atcgcttaaa tgataattta gaagaattga ttcaaggaaa aaaagcggtt
     1681 gaatcgccaa ccgctttttt acttggtggg caaccagggt cagggaaaac cagtttgcga
     1741 tcagcaattc ttgaagaaac acaagggaat gttattgtca ttgataatga tacctttaaa
     1801 caacagcacc ctaattttga tgaactagcg aaactttatg agaaagacgt agtaaaacac
     1861 gtcacccctt attctaatcg catgacagaa gcgatcataa gccgtttgag cgatcaaggc
     1921 tataatttag tgattgaagg tacaggacga acaacagacg ttcctattca aaccgcaaca
     1981 atgcttcaag ccaaaggtta tgaaacaaaa atgtatgtta tggcagtacc taaaatcaac
     2041 tcatatttag gaacaattga acgatatgaa actatgtatg cagatgatcc aatgacagcc
     2101 agggcaacac caaaacaagc gcatgatatt gttgtcaaaa acttaccgac caatttagaa
     2161 acccttcata aaacgggctt atttagcgat ataaggcttt acaatagaga aggagtgaaa
     2221 ctctattcaa gattagaaac gccttctatt agtccgaaag agaccttaga aagagaatta
     2281 aatcgtaaag tatcagggaa agaaattcaa ccgactttgg agagaataga gcaaaaaatg
     2341 cttcaaaatc aacaccaaga aacccctgaa tttaaagcaa ttcaacaaaa aatggaaagc
     2401 ttgcagccac ctacaccacc aatacccaaa acacctaaac ttccaggact ttaaacctta
     2461 aaaaaggaaa agagtagtta ccaaaaaacg gtaactactc tttttttata aaaacatttc
     2521 ctcatgtttt aaaagctgat cgagaaataa agcacacaac ggtattcttt cttttttcag
     2581 ttggtacatt ttgcagtctg taacgtgtca tttactgttt gttaccttaa catatccagt
     2641 cgaaaacaca agggtatata aacgagcaag ctcgccctgg ttctgttgca aagttagaaa
     2701 aatatagcta attggggtcc cgagcgccta cgaggaattt gtatcgataa gaaatagatt
     2761 taaaaatttc gctgttattt tgtacattta acttgacggt gacatctctc tattgtgagt
     2821 tattagtggt acagttttca accgttttaa tcataaaaaa gtggtgcatt tttaaattgg
     2881 cacaaacagg taacggttat tgcaggtgta tttcttatct atgggtttaa catggatttt
     2941 atcattaaaa tcatgagtat tgtccgagag tgattggtct tgcgtatggt taaccctaaa
     3001 gttatggaaa taagacttag aagcaaactt aagagtgtgt tgatagtgca ttatctta
//
LOCUS       DADQCX010000165         3052 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.172, whole genome shotgun sequence.
ACCESSION   DADQCX010000165 DADQCX010000000
VERSION     DADQCX010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.172"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            22..777
                     /gene="fabI"
                     /locus_tag="J8R83_002731"
     CDS             22..777
                     /gene="fabI"
                     /locus_tag="J8R83_002731"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAZ9575827.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(887..1900)
                     /locus_tag="J8R83_002732"
     CDS             complement(887..1900)
                     /locus_tag="J8R83_002732"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAZ9575828.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            2065..2985
                     /locus_tag="J8R83_002733"
     CDS             2065..2985
                     /locus_tag="J8R83_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAZ9575829.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT          888 a          618 c          588 g          958 t
ORIGIN      
        1 cagaaacaaa ggagagtcat tatgtcattt ctagaaggaa aaaaaatcgt cattatgggc
       61 gtcgctaaca aaaaaagcat tgcttggggt tgtgctgaag caatgttgaa acaaggggca
      121 gaaattatct atacttacca aaatgaacga atgaaaaaat cattagtcaa attggtcggc
      181 gaagaagcat tcactgtaga atgtgatgtt tctagcgacg aaagcatcga aaaagcaatg
      241 aatgccatcg gtgaatatgc tggggagatc cacggccttg tccatgcagt tgcttacgcc
      301 aacaaagaag aattgtccgg aaatgtgtct gatatttcca gagacggcta tcaattagct
      361 caagatatca gcagctactc tttaattgct gtatcaaaat acgcacaacc gtttcttgca
      421 ccaaacagcg ggatcgttag catgacttat ctaggttcag aacgcgcaat cccgaattat
      481 aacatgatgg gtattgcgaa agcttctctt gaagctgcta tccgttattt ggcagctgag
      541 ttctcgccta aaggaattcg ggtcaatgga atctcagctg gggcaatcaa aacattagct
      601 gtcacaggtg ttaaagacta tcaaaaactg atccagttat ctgaatctcg tacgcctgat
      661 cagcaaggtg tgacgatcga agaagtcggt aatgcttgtg ctttcttaat cagcccactt
      721 tccagcggaa tcatcggtga tattatctac gttgacaaag gtgtccatct ttcataaact
      781 tttgttgcat tctttaaagt aaaacatata aaaatcagga aaaaactttt taaagtctct
      841 tcctgatttt ttctttttac gtttttttca actcattact ttgaaattat tccacgactt
      901 caatccagcc ttctggtgct tctatgtctc caaattgaat acctgtcaat tcatcataca
      961 accgttttgt tactggtcct acttccgttt cactataaaa tacatgaaga ttgttattgt
     1021 gataaatccc accgattgga gaaataacag ccgctgtacc acatgcacca gcttctgcaa
     1081 attgatctag atcatcaatg aaaatatctc cttcaattgc ttgcagtcct agtcgttctt
     1141 cagctaactg caacaaggaa tatttcgtga tacttggtaa gatagagggc gattgcggag
     1201 tgatgaattt tccgtctttt gtaattccaa agaaatttgc tgcacctact tcttcgattt
     1261 tcgtatgtgt ggctggatca agataaacac aatctgagta atccagttct tttgcttctg
     1321 ttcctggaag taaactcgct gcgtaatttc cgccgacttt tgctgcacca gtccccttag
     1381 gagcagcacg atcgtaatca gatacaataa aattcgttgg ttttagtcca cctttgaaat
     1441 acgctcctac tggcgtacag aagacgacaa ataaatattc tggagctgga tggacaccaa
     1501 tgttttcacc gaccccaatc agtaaagggc gcaagtataa tgtagcgcct gttccatagg
     1561 gcggcacaaa atcttcattt gcttttacca cttgcttgac agcatcaacg aacatctttt
     1621 cagggaccat tggcatcagc aatcgtctag cactttgatt catccgtcga ctattttgtt
     1681 caggtcgaaa gagattgacc ttgccgtctt ttcgacgata agcttttaga ccttcaaaac
     1741 attgctgacc ataatgaagc gctggagagc cttcatgaat cgtcaggtaa ttatcttctg
     1801 tcaattctcc ttcttcccat tgtccgtctt tccatttggc aataaaacgc caaggagttt
     1861 tgatataaga aaaacctaga ttgttccaat cgatttgcat atacttacca ccttcgttat
     1921 tttctccaca ttttatcatt atccatatta tttgtcattt tattttcagc ttttttcctt
     1981 cattatagtt atttttgcta tttccttttt tgaaaacttc ttggtacaat acagaaagaa
     2041 tcaaatttta gaaaagagga ttttatgttt tcattattag caactgccgg tacgacagac
     2101 tcttctggcg agacattgac agatcaagct gtcagcaaag taaatgcgtt tcagcggttt
     2161 tgggacggga ttgattggga cgccattttg gctgccttta tccaaaaaag tttatatctg
     2221 atttttttga tcgtcctttt ttggattctt caccgtgtgg gaaaatatct gattgataag
     2281 tcttttaatc agtattctaa aaaagccatt ctaaacgaga gccgcttaaa gactttacat
     2341 agtcttttaa atactatttt tcattatacc cttggtttct tttttatcta tgcaatttta
     2401 tctgctatcg gtgtgccgat cggatcactt ttggctggtg ccggaattgc aggtgtggca
     2461 atcggtcttg gtgcccaagg gttcatgagt gatgttatta ccggattttt tattatcatg
     2521 gaacaacaga tggatgttgg ggactacatc aagctagcaa acttaacgat tgaaggaacc
     2581 gtcgtatctg ttggtatccg tacccttcag ctgaaagcaa cggatggtac tgtccatttc
     2641 atcccgaatc gaaacatcac cacgatcagc aatctctctc gtgcaaatat gcaagtactt
     2701 ttagatattc ggattgttcc tgaagaagga tatgacaaaa tctatgagat cattgatcga
     2761 gtaaatcgta cattagctga aaaataccaa gaagagctcc aaactgaacc ttctatcttt
     2821 ggattagtgg atcttggaaa cagcaatttt gcgattcgta cggtctgcta cgcattgaac
     2881 ggaaaacaat atgccttaaa agaagagttc ttgagctcct atgtcaaaga attgacagct
     2941 tctggtttca cgattccgaa cagtccaatt gctgtcggaa aataatttgg acaaacgatg
     3001 caacgaatct cactaaaaag agcgtgggac aaaagtaaag aacacttttg tc
//
LOCUS       DADQCX010000166         3048 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.173, whole genome shotgun sequence.
ACCESSION   DADQCX010000166 DADQCX010000000
VERSION     DADQCX010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.173"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(400..717)
                     /locus_tag="J8R83_002734"
     CDS             complement(400..717)
                     /locus_tag="J8R83_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9575830.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYEMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(718..972)
                     /locus_tag="J8R83_002735"
     CDS             complement(718..972)
                     /locus_tag="J8R83_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9575831.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1232..1450)
                     /locus_tag="J8R83_002736"
                     /pseudo
     CDS             complement(1232..1450)
                     /locus_tag="J8R83_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT         1011 a          495 c          424 g         1118 t
ORIGIN      
        1 catagatata ttggacttcc tcttttaaaa cacaaaaata aatactacct tatttaggta
       61 gtatttatta aaagttacgt caattttgat taaaaatata ctacttgaac ctctcatgag
      121 taaagtcacg aaatttttgg gaatagagcg tacttgatat cttatttttt cactaatagc
      181 agtgtctctt attcaccaag cgatccccgt agttcctacg gttcttaatt tttctctaga
      241 ctaatgattg tatctttaga ccttcggcca taacatggag caaaataaaa aggtactaag
      301 tcttatatat caatcttcga gtaaccgatg gttaacaacc atatcgagcg gcattaatca
      361 cccacctgta gaggatgagc gacttttgcc taattattgt taaaagccta gtttcatttg
      421 tttagattgg aaaatacgtc ctacaagtat ctcttttttt tcatggtcga tccgataaaa
      481 taaggcatag cttttgccga tcacgatccg atatgttggg atatccattt catagatttc
      541 ggaaacttcc tcatgcatag ttggaaaatt tttggttagt tctaaagcct tctggatcgc
      601 acctacaaat ctttttatgc tggctggaga aagagcaagc tcattttccc attcttctat
      661 tatcgtttca aggctggtct ggaaactttt agaataaact agcgtgtact ctttcatcta
      721 ttcactccag ccgtattttc cgaaagcttt taccatttca atttctgaaa ctgttaaacc
      781 tttctcaaag tcttggaaac tttcttcaat caatttgcga tcgtgttctt ttgctatttg
      841 agtagtatct aatatgaata agttgccttc ttgtttggct tggatagtgt ctccgctttt
      901 taatccaaga gagcttggaa ggatcactcc cacgctattg ccgatctttc taacctttag
      961 ttcttttccc atgttatcac actcctttta gtttttgata aataaattat aacatgttat
     1021 aacaacaatt gccaacggtg tttcttaagg gattccactc catattatta ttggacaaaa
     1081 taagccactt agaacgctga aaacatatac aaacgatatc aaaatacgag tgaactactc
     1141 accatacact tccgttaaca tccatttaag taggtatttt tattatatat agatttaaca
     1201 tatgtcggtc ggttgattga tatagctaaa gttataactc aaccgaagcc gatttatcta
     1261 cacgaataaa gttgcgagtg ttctcggcta attcataaaa attgttatgt gttccatata
     1321 gcaatactgg aataacttta ttttcttgaa tctcagaagc aactctatac acggtgaccg
     1381 catacttaaa tccattagac caattacctg ataaacctcc agttttttgc tcttacttaa
     1441 atggatcaat agaaatttca tcacaaacct atagaggatg agtgacttct gcctaattac
     1501 gttaaaaaat attgaaagta actctatgta gcaaaaaata tctagaattt catttcctca
     1561 aaactgatcg atattgtatc caaaaatata tactacctaa aataggtagt atatattaaa
     1621 atatgtgctt ttgttagaaa aatcaataca taaattatca tatctgtata tgtcatttag
     1681 gtattttagt tatgttataa tagttttgct gtctgctacc ccggcctaat ctggcaaggg
     1741 gaggaggaga tataatgaaa tacctttttg attttgtttt tgcaatcaag ccatttgcag
     1801 aggtaactgc acactacatc tgcaagtggc ttgattgcaa aattgccaaa aaagacagta
     1861 agcctacccg ttaattctat aatatagaaa cgtaaaaaaa aaccccatca gcctgcacgc
     1921 tgatggggtt tggtgatata atgaaatacc tctttgttac tcataattat accataatta
     1981 gtcacgaatg caaccaatag aaaaaactac ttagaacggt agatcatcgc taataacaat
     2041 gcattgtcca ccaaatggat tttgtgaagc attaaataca ttgttattaa ttgtcgctgc
     2101 ttttaactag gcctctcccc ttctattata aaagaagata tatatcattt cttaattacc
     2161 tactacctta aaccaaaatt taagtactac ctaatttaag tagtacttaa ataatctaaa
     2221 aaatagttat cccaattgtt atgattttat aatacgatta tttgtaacaa aatgaatatt
     2281 atataattaa acactaccat atttaggtag tgtttaatta ttagcaaaac aaaaaatatt
     2341 tattctattc tcttaacttc aactaagtta tgctgcacat ctttatataa atcatatgca
     2401 actcattagc tagacaaact acaagcatgt agttttatct gttaattatg tactacctaa
     2461 ataaagtagt ttataattaa caagtatata tatttaaaaa tttaaaatta atttttttat
     2521 gacttgtaca aatttatctg atattctctt attaagaact acctaatttg ggtagttctt
     2581 attttttaca ttttaagtag tatttaattg caatttggta gtattttttt attatcttat
     2641 tcctagaacg gtagtactta atataaatat aggtagtatc taatttaagt attaatggta
     2701 gtatctaatt taacaggtag tatgtaacta ctttaaagta atttttttca gattaacaca
     2761 gtagtatctt attaaataag ttaattctaa aggtagtaca taattattat atatatctaa
     2821 cattggtagt acttattgta ttttttagta gtatataatc tattgttttc tagcctaaag
     2881 ccttgtctta taagaataat ataatatata ctactgaaat aaggtagtat atattactag
     2941 tagtggtagt atgttttata tgcataaggt agttcttaat ttattttttg ttttgatact
     3001 ggtagtactt aattatcctt aattttaaaa ccaaatttta ttcatacg
//
LOCUS       DADQCX010000167         2992 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.174, whole genome shotgun sequence.
ACCESSION   DADQCX010000167 DADQCX010000000
VERSION     DADQCX010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.174"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(106..1053)
                     /locus_tag="J8R83_002737"
     CDS             complement(106..1053)
                     /locus_tag="J8R83_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9575832.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            1299..1763
                     /locus_tag="J8R83_002738"
     CDS             1299..1763
                     /locus_tag="J8R83_002738"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAZ9575833.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(1825..2868)
                     /locus_tag="J8R83_002739"
     CDS             complement(1825..2868)
                     /locus_tag="J8R83_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAZ9575834.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
BASE COUNT          990 a          593 c          571 g          838 t
ORIGIN      
        1 agaagctact tctggaacac catttattcg gaaaaaagga ctgtgacaag acttttgtca
       61 cagtcctttt tcatttaaaa aaatgtttac ttcatttgac gtatattatt ggtgaggctt
      121 caattcattt ggcttcactt tttctgtttc tcttatgata taaacaggac gctgtttcgt
      181 ttctaagaag attttcccaa tatatttccc gatgattcca agacataaca attggattcc
      241 accaatgaac aggaagatcg agaccatgga aggccatcct gatgtaggat caccaaacaa
      301 caatgcccgc aaaataatga acaaaattgc aataccagaa ccgacacaag acaaagcgcc
      361 gataaatgaa gcaatcgtta acggtgcatc cgagaagttc acgataccat caatcgagta
      421 gttgaataat ttccagaagg accaagatgt ttcgccagcc acacgttcgc ggttttcata
      481 agaaatatat tctgttttaa atccgaccca gctaaataat ccttttgaaa atcggttgta
      541 ttctgttaat tctaggacgg catccaccat ttgacgagtc atcaagcgga aatcacgagc
      601 gccatcgacc atttctgtat cgctgatttt attgatcaac tggtagaatt ttttcgcaaa
      661 gaaactgcgt atcgcaggct cgccttcacg agtcgaacgc cgggtgccga cacaatcgat
      721 atcagaagta gtgatccggt tgatcatctc aggaagcagt tcgggcggat cttgcagatc
      781 aacatccatc acggtcacta aatctcctgt agaagcttgc aatccagcgt acagagccgc
      841 ttctttccca aaatttctgg aaaatgagac aaagcggaca taaggataag ctgaggctag
      901 cttcttgatt gctgctaacg taccgtcttt tgatccgtcg tcaataaaca aatattcgaa
      961 ctcatgggca cctttgaatt tttcaacctc atcaaaaaaa agaggaacag ttttttcttc
     1021 attaaaacat gggacaacaa ttgatacttt catcgtttct atcctttcaa tcgtatgttt
     1081 atatatggtt tacattcaaa atttaataaa ccttaaataa cacctttaaa atttgatttt
     1141 acgtaaaaga acaggtattc tttttgtaaa ctaacgtatt tagtttacca tgtttcctcg
     1201 gtttatcaaa cttttaagaa caatttttat tagttggcaa gtagttttgg atagagaaaa
     1261 aggaggaagt tccagtctat tgactaggag caaacaaaat gaaaatacac acacctatcg
     1321 gctttttatg gttagatgca gatgaatccg gattgactgc tgtatctttt cagccaattt
     1381 cagaaagcga atcagcgaat cagcgaattt taacgcgcac acaagaacag tttgaagaat
     1441 attttgcggg aaaaagaaaa gaatttgatg ttcctttatc tataaagaga ggtacgcctt
     1501 ttcagcaaaa tgtctggaaa gctttgtcga ccattcctta tggagaaatc cgaacgtata
     1561 aagaagtagc cgttgctgtt gatagtccga aagctgtgcg agcgattggg caggcaaatc
     1621 gaaccaatcc attgccaatc gttattcctt gtcatcgagt gatcgggcaa aatggaaaac
     1681 tgacaggata tatgggaaac gcaatagatg gggttgaaat caaacgccaa ttgttgttgt
     1741 tagaaggata tctgcaaaat taaaaacagt tgtgattcgg acattgttcc atgcgagaat
     1801 cacaactgtt ttttcatgtt cattctaaac tttgatcagc caaataaata gtaaagccat
     1861 cactgtttgg agaagcccga cagctaatcc ataagataag aagcgtgtac cttctttcat
     1921 gaattttgca aagtctaaac gcagaccaat tgccgctaaa gcagtgatct caaaccagct
     1981 gctgataaaa tgtgccgatt ggtcaataac tacaggtaaa gaaaacaagc tgttgaccaa
     2041 acaaaagatc acaaacccta atacatacca aggaagcggt aattttcgtt ttttctgcgt
     2101 atcagttggc gtttcaaaca gagctggttg tttcttgtgc atgaattttt caaacagata
     2161 gacaacaaca acgagcatca taatacgtag aatcttaaat agcatggcga attcgacaac
     2221 agaattgtca agtaagcttg ccccagcgac tacttgacca acagattgga gtgtaccacc
     2281 caaaagtgca cttttttcaa tgagatttcc accaaacaac tgtaatccaa gaaaagggag
     2341 agtcaacatc atcacagtac ccagtagatt gactagtgtg atgatctgtc ctttttcttc
     2401 ctctttcgca tggatggaag gggcgattga agcaatagca gaagaaccac aaacagcgtt
     2461 tcctccagcc atcatcaaag aagaagtatc gctgaattgc agttttttac caatcaagta
     2521 agcaccgatg atagtgactg acatttgcag taacacaaaa acaattcctt ttacaccaat
     2581 ttgagcaatc gtttgagctg tgacagttgc acctagtaaa aaaacagaga attctaatag
     2641 tttgctttca gcaaattttg tgccgattgc tagaacaggc tgtttaaaaa aagtatttcc
     2701 taataaaata cccaataaaa tagcaatagt cgctccacct aactgtggca gataaatagc
     2761 aagaagcctg ctgaaggcag cgatggcaaa agaaagcagt aaaccgggta agatttcgcg
     2821 gaccgctgaa tcctttacag attttattgg atgtgacaat gatttcattt gatcggttcc
     2881 tttcgtcaat aaatactaaa agcatactcg aacatagtag cactaaacca gtattttgac
     2941 aaaagaacaa gaggtcgtga caaaagtctt gtacgacctc ttgtttcgaa ta
//
LOCUS       DADQCX010000168         2955 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.175, whole genome shotgun sequence.
ACCESSION   DADQCX010000168 DADQCX010000000
VERSION     DADQCX010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.175"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            7..729
                     /locus_tag="J8R83_002740"
     CDS             7..729
                     /locus_tag="J8R83_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAZ9575835.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            787..2826
                     /locus_tag="J8R83_002741"
     CDS             787..2826
                     /locus_tag="J8R83_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAZ9575836.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
BASE COUNT         1046 a          522 c          626 g          761 t
ORIGIN      
        1 tctattttgt tactgcttac attagtagtt ggctattttt cgattgagtt tatccatgga
       61 ttttcgtctg caaaacagag ttcaactgtg aaaaaggtag agccgaaaag tatccctacc
      121 acactaaatg tggctttgat tggttcagat gctcgttcga aagacgaaaa cggtcgctcg
      181 gattcacttc tggttgcaca atacaaccag aaaacacaac aagcaaaact gatctctatc
      241 atgagagatt catatgtcga tattccaggt tacggaatga ataagataaa tgcagcttac
      301 tcttatgggg gagttgattt attaaatcaa acattaaagg aaaatttcaa atttgaagct
      361 ccctattatg caagtatcac atttcaagat tttatcgatt gcgttaatga actgtttcct
      421 ggtggagtca agatcgatgc agaaaaatct ctagatttag atggcgtata tataaacaaa
      481 ggagagcaag tgatggatgg taatacttta ctccagtatg ctcgatttcg ggaagacaaa
      541 gaaggagact tcgggaggat cagaaggcag cagcaagtga tcaaagctat ctctcagcag
      601 ctgaaagacg taacttcaat attcaagcta cccaaagcgg ttgggaaatt acttggtagt
      661 atccaaacga accttccaga aagtgtgctt ctggattgtg gtatggattt cctcaaagac
      721 atatgttaga ataaacaggt ataaatagtg aaataaagga atgacaagca agagaaggag
      781 gaaaaaatga aaagaagtga caagcacggc aaaaatcgaa caggcgctta tattgccggc
      841 gcagtgatct taatagcagc tgcgggtggc ggttattttt actaccagca ctatcaagaa
      901 acccaagcag tagaagctgg agaaaagaca gttgagcaat ttgtccaagc tttgaacaag
      961 ggagattata acaaagctgc agaaatgaca tcaaaaaagg cggcaaataa aagtgcatta
     1021 tctgaaaaag agatcttaga taaataccag aatatatacg gtgctgctga tgtcaaagga
     1081 cttcagatat cgaatctaaa agtagataaa aaagacgatt ctacttacag tttttcatat
     1141 aaagcaaaga tgaatacctc attaggtgaa ttgaaagatc tttcttataa aggaacatta
     1201 gacagaaatg atggtcaaac cacgatcaac tggcaaccca acttggtttt tccagaaatg
     1261 gaaggaaatg acaaagtaag cctgaccaca caagaagcag caagagggaa tattatagat
     1321 cgaaatggtg aaccattagc aacaacaggc aaactaaaac aattaggagt cgttccaagt
     1381 aaacttggag atggaggcga aaaaacagcc aatatcaaag cgattgcttc ctccttcgac
     1441 ttaacagaag atgctatcaa tcaggcgatt tcacaaagct gggtacaacc cgattacttt
     1501 gtcccattga aaatcattga tggagcaacg ccagaacttc cagctggagc taccattcaa
     1561 gaagtagacg gcagatatta tcctttgggt gaagcagctg ctcagctgat tggttacgtg
     1621 ggagatatca cagcagaaga tattgataag aatccagaat taagcagtaa tggaaaaatc
     1681 ggtcgctcag gtttggagat ggcttttgat aaggatcttc gtgggacaac aggtgggaaa
     1741 ttaagcatta cagatgcaga cggtgtagag aaaaaagttc tgatcgaaca tgaagttcaa
     1801 aatggcaaag atatcaaatt gacaatcgat gcgaaggcac aaaaaacagc ttttgacagt
     1861 ctaggaggaa aagctggatc aactgttgcg acaacgccaa aaaccggtga tcttcttgcg
     1921 cttgctagct ctccaagcta tgatccaaac aaaatgacaa acgggatctc acaagaagat
     1981 tacaaagctt atgaagaaaa tcctgaacat ccattcatca gccgatttgc gacaggttat
     2041 gctcctggat ctacgtttaa aataattaca gcagcaatcg gtctcgacaa cggcactatc
     2101 gatccaaatg aagtgttgac gatcaacggg cttaaatggc aaaaagacag ttcttgggga
     2161 tcttttcaaa caacgcgtgt cagtagtgat gtatcacaag tagacttaaa aactgctttg
     2221 atctattccg ataatatata tgcggcacaa gaaacgttga aaatgggtga gaaaaaattt
     2281 cgtacaggct tagataaatt catttttggt gaagaccttg atttgccaat tagtatgaat
     2341 ccagcacaaa tttctaatga agatagcttt aactcagata tcttgctagc tgatactgga
     2401 tatggacagg gcgaacttct aattaatcct atccagcaag cagcaatgta ttctgttttt
     2461 accaacaatg gcacacttgt ctatcctaaa ttgattgcag ataaagagac aaaagataag
     2521 aagaatgtca tcagcgaaac agcagtacaa acgatcgtgc cagatctgag agaagttgtg
     2581 caagatgtaa atggtacagc acattctctt tctgctttag ggattccgtt ggcagcgaaa
     2641 actggtacag cggaaatcaa agaaaaacag gatgtaaagg ggcaagagaa cagtttcttg
     2701 tttgctttca atcttgataa ccaaggttat atgatggtca gcatgttgga aaataaagaa
     2761 gatgatgatt cagcaaccaa acgagcatcg gaactattgc aatacctcaa ccaaaattat
     2821 caataaaaaa ttgcttttta agtacagtaa aaggactgtg gcgttatcgt cacagtcctt
     2881 ttttcaaata aacggttttc acgatgtctc tttcacaact tctttttgat ttactcacac
     2941 ttcataaact ttttt
//
LOCUS       DADQCX010000169         2893 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.176, whole genome shotgun sequence.
ACCESSION   DADQCX010000169 DADQCX010000000
VERSION     DADQCX010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.176"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            243..587
                     /locus_tag="J8R83_002742"
     CDS             243..587
                     /locus_tag="J8R83_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAZ9575837.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            588..1007
                     /locus_tag="J8R83_002743"
     CDS             588..1007
                     /locus_tag="J8R83_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAZ9575838.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1099..1449)
                     /locus_tag="J8R83_002744"
     CDS             complement(1099..1449)
                     /locus_tag="J8R83_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575839.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1415..2746)
                     /locus_tag="J8R83_002745"
     CDS             complement(1415..2746)
                     /locus_tag="J8R83_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAZ9575840.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
BASE COUNT         1079 a          514 c          547 g          753 t
ORIGIN      
        1 gggtattaca atttgagtgt aacataaatg gcttttttat ttgtctcgct taattataca
       61 aacggcgtaa aataaaaaaa gcgttagcaa ctatgcttaa aaagcatatc gactgaataa
      121 actaagcatt ggacaggctg aaagactaca tttaaaatga aatgcgaaga aacaatagaa
      181 aataaagttg ccttagaacc atagttgaat cacctaacag tcgtgaaggg agaataagag
      241 aaatggcaga aaaacaaacc gcaggacgag atcaattagg agattttgca ccaaaatttg
      301 cagaattaaa tgatgatgtt ttatttggac aagtatggtc cagagaagaa ttatctgctc
      361 atcagcgtag tatcatcacc atatctgcat taatttcagg aggaaatttt gaacaattgc
      421 cagctcatct gaagattggc aagcaaaatg gcattactag tgaagaaata gcagaaatca
      481 ttacccattt agctttttat gtagaatggc caaaagcttg gtcagctttt agtttagcaa
      541 aagaaatcta tttagaagaa aatagcgaag ataagaaaga ggcgtaaatg atgacaaaac
      601 acgaagaaat acacaatggc gtgatttttc cagcaggtga aaaaaacgaa gcttacgctc
      661 aagtatttac cgggcaaagc tatctgaata tgttagtgaa tgatcccgaa gtttctgttg
      721 gtgtaggtaa tgtaactttt gaaccaggtt gtcgcaatca ctggcatgtc catacagacg
      781 gctatcaaat cttacttgtg accggaggag aaggctggta tcaggaagaa ggaaagccag
      841 caagacgatt aatggctgga gatgtcgtcg taacgcacaa agggattaaa cattggcatg
      901 gtgcgacaaa agacagttgg tttgaacatt tggcgatcac tgctggtaat tcagagtttt
      961 tagaacctgt aacagatgaa gtgtatgaag gattggaaaa tcaataatgt caagcttgaa
     1021 cagctcctga aagtagattt taatcgaact ttcaggagct gcttttttga ttcagtcttt
     1081 tataaataga aaatagggtt aataatagga atgagaagca cgtcgaaaga tcttaatatt
     1141 gataatcggc tgggcataca tgatttccac gtcatcaatc aaactaccta acagatgata
     1201 atcttcccga tcatgtcggg gattacctaa tagttcttga tagtagattt ccatactagg
     1261 gtcccgagga ttgttcagca aatcagcaag tacatctaaa tcttctggct gagtttctgc
     1321 cgtaccctgt atctctatga aaagcccttc ctcagcaaat tctactccaa tacgtatttc
     1381 agttatttca tgggaatata aataagtaag aagctcatcg atgattcttt ttgataattc
     1441 tttttccaag tgtctttttt tcctttctga cagcggtaaa gttatctagt atcggtacaa
     1501 ggatacctgc aacgaaacca gttgaaaaac cactgttata tagatttagt cctccgtgca
     1561 aagtgctgac gttatggaca agagcaatat gtagcacacc agctattaca ccgtaaaaac
     1621 tgccgtaaaa accgcttatg ggcgcaagac ctgtcccaaa cacagctgca acaagcatgc
     1681 cagtactggt gatctcatga aaagttccaa acaaagaagc aataaatatt ccgactagta
     1741 tcggaaaact gttttttaaa tgacaaccaa aagcactgaa acccaccgca gataaaatag
     1801 caccgatgac aggtccattt aactgaccgc caaccagcaa aacataagaa gacagcatca
     1861 gaccaactaa gcccatgttg atcaaagtag caccaatacc agaattagca atgaaatcag
     1921 ttgtcaattt tccagatgaa tcgaaaattt ctcgaatccc cgaaagccga aaggaattat
     1981 aatagaaacc aattccgact gtcagcgaaa aaaagccaaa aataatccaa atgagaggaa
     2041 agtgatattc attgaaaacc aatgtatttt cgacgattga atagctgaat aacctcaaaa
     2101 cagcagtaaa agtcatcgca atcaacccag aggtgaatcc aatattataa agtgtgaatc
     2161 cacgatggaa aactaaagtt tgagcagcta agggcggaag aagtatacca attgctatgc
     2221 cagctaaatt ccccaataaa atacctatca gtaaaggaaa acgcatacca aaagtgatat
     2281 aactaacgac cggtgataat acgctaccaa acagtccgat catgatgtac tgagaaaaag
     2341 gtttattgac aaatacagcg tatagataca cacctaaaat gattgagata gaattataaa
     2401 ggtttttgcc aaaaaaagag aaaccggtaa ctgttagaat cgaagcaaat aagggaccgt
     2461 ttaaaatcac cttgtgccga taagctaaaa gcacagaaag taaggtcaaa atccctacat
     2521 ttatgaatgc gcttccgaaa acacctaaag caaaataatc tgtcaaaaga ttgcttggcg
     2581 aggtaagaat agttagcaat ccactccaat tatcagtagg agtattagaa agcaagccaa
     2641 taaaaagaaa aaaaacacct gtaaaaccaa gataaaaata ctttcttttc tgtgaaacga
     2701 ttcgtttttg aggatgaata taaataacgt cagtttcgtt ttccattaca caccttcttt
     2761 ttcattttct ttaactataa cttgaaatga aagatttgga caactatcat ttaggtcaaa
     2821 actaaaaatg taagggaacc cattgaattt aaccaaattt ttttaatttt gcaaaaaaaa
     2881 gttaaagaag act
//
LOCUS       DADQCX010000170         2812 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.177, whole genome shotgun sequence.
ACCESSION   DADQCX010000170 DADQCX010000000
VERSION     DADQCX010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.177"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            181..504
                     /locus_tag="J8R83_002746"
     CDS             181..504
                     /locus_tag="J8R83_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575841.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            668..922
                     /locus_tag="J8R83_002747"
     CDS             668..922
                     /locus_tag="J8R83_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575842.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            992..1237
                     /locus_tag="J8R83_002748"
     CDS             992..1237
                     /locus_tag="J8R83_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9575843.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            1313..1678
                     /locus_tag="J8R83_002749"
     CDS             1313..1678
                     /locus_tag="J8R83_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575844.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1739..2302)
                     /locus_tag="J8R83_002750"
     CDS             complement(1739..2302)
                     /locus_tag="J8R83_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575845.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT          832 a          491 c          432 g         1057 t
ORIGIN      
        1 aataaaattt atttttgtta cttttcaact atagcacgaa tgacaaactc tcacaagttt
       61 caaaatataa gtaaaataat attgttattc ttatttcttt tacttgtgtc ataactattt
      121 tgttacttta atttttattt gcttatttta gaaaaaatgt tattctttta tttattctca
      181 atgttaggag tgattatttt gccatttatt gcgattttat tcgatttagt tgcggcagca
      241 gcttattttc tccaattaaa ttatcaaacc tcaggaattc tgtttattgg aatgattttt
      301 caaggtgtga ttaccctttt gcttcttgtc atgatgctca gctataaagg aaaaagatat
      361 gcccgtattc aaacaaaagt atttgttaaa tatgtttcca ttcgctatgg gatcatcatt
      421 ctttcctttt tagtgaatgc gatcgtcctc tttttatatg tattgaatta cttagatatc
      481 aatccattga ttttttctcg atagataaga cacattcagc ggaacagttc ctgcttatca
      541 gcagaaaact gttctgcttt ttcatttttc attgatctat tcttctttta ttttcctagc
      601 atttcatttg tgatgtatgc aataacatgt tatcttttat tatatgaatc gttgaggagt
      661 ccgttacatg attacgttgg tgagagtttt gttttgggtg cctgcggtcg cactggtcgc
      721 aagtattgtt tatcttatga attggaacaa agaacggttt tatttagcta ttttgactct
      781 tccggctatc tactttatgt ggaaagtttt taattacaac tactttgaac ccgatagtgt
      841 ttttatagaa gaattatcag gactggtttt gtctttattg atcgtcattc tttatttgat
      901 acgtttaaat aaaaaacatt gagtactatt gattgcatgt gtagctttct atagtcatta
      961 taactattct actataatga aaggtgatta aatgagtatc gaagaagcta ttttactgga
     1021 tactttacgt tgtcgtctga atttcttaag aactggccga tctttatctc aagtagctgt
     1081 ttctagcgcg ttaagtattc ctttattcaa atatcgtaag tacgaagaag gagaagaaat
     1141 tccaagcatc attgaattaa tctatatcgc tgacttttac gatatttccg ttgattacct
     1201 aattggtcgc tcagaaacag caagcaaact gaagtgattt tttccagcct tggtgctggt
     1261 tttttcattt aacgtctaag gttaacaatc tatatataaa ggagacattt ctatgcgatt
     1321 atggcatgaa aaattgattt caaagcttcc tcgtcaacag cttttaggac aacatcggga
     1381 atgctgtgca ttaagaggaa atggctgggg aaagaaacat gctactgtgg attatgtttt
     1441 tcactattct ccttatagat tattccaata tcatcagctt gtcatggatg aaatggaaaa
     1501 acgtggttac agcccagcac cagagtggaa aaatcctatg tatcgtggca aatcatgcga
     1561 agcatttttt gatttaccta ctgtagagcg caacgtgccg atttatccgg aacacgatga
     1621 agtttatcta gcagaatgtt tagcaaattt ggagcaaaaa ggaatttatc ttacctaata
     1681 taactagaaa agccttctat ctcctcttac ttcattaaaa agctttaacc atcttagatc
     1741 aagctaaaat gtcgtaagtt ttagggttat cttcatcctc acgtgcaaaa ctaaaagcgt
     1801 actctagttt tggttcatcg ccaacttccc tagacataaa tgaacatctc ctgacgtggt
     1861 ttaaaagtac cgcatcttcg acgtctgtat acgatgcaca gcacagattg cttcttttga
     1921 tctttctttt gatttttctg ttgcttcttc tacaccttct tcgattacta catcgatgct
     1981 tacaattgct tctgcctaat attcccatgc atcgtcgatt taagcctctg tagtcactgt
     2041 gatcgtttcc acattttaac tcctctgtcg tggcttcagt tgattttgtg atcagttcag
     2101 ttgctaagcc agagtcagaa caacctgcca ttgctagcgt taatattgat agtaaaaata
     2161 gtttttttat cataaggttc cccccctgaa aatagactaa aataataacg ctttcttttt
     2221 ttgttttcag acgaaaatta ataatttcta aatattcttt aaaaaagctt ataactatta
     2281 tgcctttttt aatatataac acagttattt ttaaaaataa gaatgctaaa tcactctaca
     2341 ataacggcga aagcacaaaa aataaaaaaa ttattacgtt attaaaaaaa cagatgaaag
     2401 atcaggtttt attagatctc attctttcat cacttgaagg gatttaatga actacttttt
     2461 cctctttgtc gtttttatat attcgtattc cttcaaacag taggatagcc tctttcaatg
     2521 cttgatattt gaactgtccg ttacttaaaa atttagatgt gccgccctct tcctagaaca
     2581 tattcttttt tactttttca ttaattgaca gaccaatcga acgaaactgt aaatttcgat
     2641 aggataatga ttggtcaaac tcattcattt tcaagacatc tcgattcata ttcaagatag
     2701 gaatcttttt atcaacatca ctttattcgt attttcctct accataaaag cttcacgctc
     2761 cacaaaattg ttttatacac tactattcag cccattcaac gaccaatgaa tt
//
LOCUS       DADQCX010000171         2726 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.178, whole genome shotgun sequence.
ACCESSION   DADQCX010000171 DADQCX010000000
VERSION     DADQCX010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.178"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1092)
                     /locus_tag="J8R83_002751"
     CDS             complement(<1..1092)
                     /locus_tag="J8R83_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAZ9575846.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1281..2042
                     /locus_tag="J8R83_002752"
     CDS             1281..2042
                     /locus_tag="J8R83_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9575847.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2157..2597)
                     /gene="fabZ"
                     /locus_tag="J8R83_002753"
     CDS             complement(2157..2597)
                     /gene="fabZ"
                     /locus_tag="J8R83_002753"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAZ9575848.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT          857 a          544 c          462 g          863 t
ORIGIN      
        1 ttttttattt tcaattaatt taaagcttga ccatggtttc aaaaagtcaa ggaggaataa
       61 ttcgtcatcg gagattcttc ctacaacatt gacacgtccg tcgtttttca tatccttcaa
      121 ggcgatttgt gtttctcctt tgtattgacc gtacccttca ttgtcaatca gtacatcccc
      181 atgatgcata tctcgcgtat tatgaggcgg gaaatcttta tctttgtagt atacacgagt
      241 catcgttgaa cgaaggatat attctgagcg atcccctcga taactatgaa ggttatcaaa
      301 caagcagatt cgttcgtttt ctgtaatacc ttcttccgta tctactttca atgttggata
      361 atccgcgtta aatgcttctg ccatttcttt caattcttct tcacttgcgt acgcatttcc
      421 aatagaaata tcatcaatca atcctgtaag gattaaatgc ttcacttgtg tcgcaatttc
      481 aagatctcgg tggtcttcca gcgtgcacaa gccatcttgc gtaggccaag ggccaaactc
      541 agcagattgc gaattgacga atgccatcgt attcaaatta tattttctga atttttctga
      601 acaaaaaaca aagtgttcgt atcctaaacc agagtatcga tgaggataaa aattatgaga
      661 acctaataaa ttatccgtgt ttggcgaata actcatgatg ttgtcaacgt aattcgtgcc
      721 cgaactcata ttgatctcga ttttgatacc aaaaggattg cgcgtcattt ttgcttcttc
      781 tgctcctgtg aatccgatat ctaagcggac cccgtaggca cccatcttat ggaaaaaaga
      841 taagtcatcg taagaaatct ccaactgttc aaataacgct ggattgatat caaccattac
      901 ttccatgcct aggctattcg cgtaatcaac tacttcttta aattctgaaa gaactttttc
      961 tttatcatca ttgatctgca gcaaactggt aaaaacccgt ttatacccat acttatgagc
     1021 taaatccaag tacgctttgt ccttttcaaa tgttgaccgt tctggataaa tcgagattcc
     1081 taattttccc atattaccat ttcctcctgc atcttttcgt ttttgtatcc acttacatta
     1141 tagcaaacac aaagtaaatg gtctacacct tttctttttc ttttaaaata aatgataaat
     1201 tccaataatt taagtaggta ttttccctct attttgttat cattaaagat aacaaaatag
     1261 taaattggaa aggaacagtt atgaagaaaa ataaagttat tttaagtatt agtttagcag
     1321 cagcattgct gtttgctgct ggttgttctg caaacaacac gacttcttct agttcgtcta
     1381 cagaaagttc aaaaagtaca tctactgcgg aaagcacgac tgccagtagc gtcgatttga
     1441 acgcattgga attaccacaa ttgacgaaag atgtcgccga aaatgaagat ctggtcgaaa
     1501 tggtgacgaa taaaggcaca atcaaaatca aattatttcc cgaacacgca ccaaaagcgg
     1561 ttgaaaactt tatgacacat gcaaaagacg gttactacaa cggactgact ttccatcgcg
     1621 tcatcaaaga tttcatgatc caaggtggcg atcctaaagg cgatggcact ggaggggaaa
     1681 gcatttgggg agaaggattt gaaacagaga tcaacaacca cctttataat ataagaggtg
     1741 cgttatctat ggctcgctca caagatccta acagtaacgg cagccagttc tttatcgttc
     1801 aaaatacaga tgatatgcat gatggtcttt taaaagacga ctatcctcaa gcaatcatcg
     1861 acgcttataa aaacggcggt tatccttcac tagatggcca ttatactgtc ttcggccaag
     1921 tgattgaagg aatggatgtc gtggatgcta ttgcaaatat cgaaacagat agttcagaca
     1981 aaccaaaaga agaagtaaaa atcgataaaa tcaatatact gcaagaagca aaacaaaaat
     2041 aaaaaaataa cgtctgaatc ctgcatagat gacaacgtat gctaggattc aggcgtcttc
     2101 tttttacata aaaagcaagt aagcttcctt ttgttttgct atatcaggtt ttatagtcaa
     2161 gcattttggt tgacgatgaa cgtgaactcg cactcacaga cttttttatc atctacatat
     2221 gctgcagata acgctgtacc gactgatccc ttcattttgg tgatttcaaa atgacatttc
     2281 agcacatctc ctggaacaac tttttgacgg aatttggcct tattgatccc accgatataa
     2341 gctctttttc ctagaaactc ttctgatttt aggataagta tcgaacctgc ttgtgccagt
     2401 gtttctagaa tcaacgcacc cggcatcact ggattgtcag gaaagtgacc ttggaaaaaa
     2461 tcttcattga ttgttacatt ttttgtcgca acgatctttt ttcctggttc taaagtatct
     2521 acataatcaa tataacaaat aggataacga ttaggaatca attccattac ttcagtagca
     2581 gataatacgt aagacataat taaactcctt ctttcaggca attgccattt tcattacttt
     2641 gactatcaaa gtatcatatt cctaaatatt tagcaatctt tttttaattt aagaaaaaat
     2701 agtttgacaa tcaaaacatt ttgact
//
LOCUS       DADQCX010000172         2633 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.179, whole genome shotgun sequence.
ACCESSION   DADQCX010000172 DADQCX010000000
VERSION     DADQCX010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.179"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..1149
                     /locus_tag="J8R83_002754"
                     /pseudo
     CDS             5..1149
                     /locus_tag="J8R83_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1320..1778
                     /locus_tag="J8R83_002755"
     CDS             1320..1778
                     /locus_tag="J8R83_002755"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAZ9575849.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1937..2407
                     /locus_tag="J8R83_002756"
     CDS             1937..2407
                     /locus_tag="J8R83_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAZ9575850.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2460..2575)
                     /gene="rrf"
                     /locus_tag="J8R83_002757"
     rRNA            complement(2460..2575)
                     /gene="rrf"
                     /locus_tag="J8R83_002757"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          770 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccaa aagatctagc cgatcagatc
      661 ggattttacc aaaatgctat cggagccgta cttggtcccc aagatagctg gttacttcag
      721 cgcggaatca agacactaag tgttcgtatg gaggaacatc aaaaaaatgc ttttgtggta
      781 gctgattttc tattttctca tccagcagta gaaaaggtct actatccagg attacccgat
      841 catgaactcc atggagttgc taagcagcag atgagcggct ttagcggaat gatttctttt
      901 actttaaaaa atgaagaatc tgctattcca tttgttgaat cactccaact atttacttta
      961 gcagaaagtt taggtggcgt agaaagttta gtggaaattc cttctgtcat gactcatgcg
     1021 tctattccaa aagaaaaacg agaagaggct ggcataaagg acggcttgat ccgtctttct
     1081 gtaggaattg agtatggtca ggatctcata aacgatttag ctcaggcatt tgacagaatc
     1141 aagaactaga agtcccaata aacgacttag cagaaaaatc taaaaaatat ttcagattgc
     1201 tacaccttgg aaacgataag tgttagaatc aagtagaaag acgtttttgt aaatttcact
     1261 aaataattct ttagtgaaaa gcatcaaaac gaatgaacaa acagatagga gtcttacaaa
     1321 tgagaatgaa tgtcgaaagt tttaatcttg accatacaaa agtcaaagca ccttatgtac
     1381 gtgtagctga tcgaaaaacg ggtgcgcatg gcgatgtcat cattaaatac gacgtccgct
     1441 ttaaacaacc aaataaagaa cacatggaca tgccaagtct acattcactt gagcacttga
     1501 ctgccgaact aatccgcaat cacgcagatt acatcgtaga ctggtctcca atgggatgcc
     1561 aaacaggctt ttacttgact gtattgaatc atgaaagcta cgaagacatt ttagatgttc
     1621 ttgaagcaac aatgaaagat gttcttgaag ctactgaagt acctgcaagc aatgaaacac
     1681 aatgtggctg ggctgccagc catacactag aaggtgcaca agctttggct cgtgaatttt
     1741 tagcaaaacg cgatgaatgg tctgaagtag aagcatagtt tctaaaagaa cgtaaagatg
     1801 agaagcaata tagctatctt atcttcgtat tttattaaat atttattgtc tgaaaagagt
     1861 tctaaacggg aaaacaaata gctagttttc agtttagcgc tctttttatt atataaaata
     1921 gaaaggagaa aactttatgt ctatttataa ttttgaaact actttagaag acggcactgt
     1981 ctattcattg aaaaaatatg caggcaaacc gataatcatt gttaacactg caacaaaatg
     2041 cggtctagca cctcaattta aacaattaga agaactttac caagcttatc agacacaagg
     2101 tctggttatc ttaggctttc cttccaatca atttaaacaa gagctagatt cagcgactga
     2161 agcagcagaa gcttgtaaaa ccacttatgg cgttaccttc cctatgcatc aattgattga
     2221 cgtaaatgga gaaaatacag atcctctttt tacttatctt aaaaatgaag ctcctggtac
     2281 tgtcactaaa gcaataaaat ggaattttac taaatttttg attgatagaa atggcaaagt
     2341 aatcgaacga tttgcaccac aaacttctcc attgaaaatg accgctgcaa ttgaatccgt
     2401 tctttaactt aataaaaata aaaaaagatg aactatttct agttcatctt tttgcctttg
     2461 cgtggcgacg tcctactctc acaaggggca acccctcact acaatcggcg ctaagaagct
     2521 taacttctgt gttcggcatg gttacaggtg tatccttctc gctatcgcca ccacactgtg
     2581 gtgttatctt ttattgagta aattttgttc actcaaaact ggatttgaag tca
//
LOCUS       DADQCX010000173         2593 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.180, whole genome shotgun sequence.
ACCESSION   DADQCX010000173 DADQCX010000000
VERSION     DADQCX010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.180"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1152
                     /locus_tag="J8R83_002758"
     CDS             <1..1152
                     /locus_tag="J8R83_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575851.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="J8R83_002759"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="J8R83_002759"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAZ9575852.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
BASE COUNT          859 a          491 c          620 g          623 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca act
//
LOCUS       DADQCX010000174         2559 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.181, whole genome shotgun sequence.
ACCESSION   DADQCX010000174 DADQCX010000000
VERSION     DADQCX010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.181"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..902)
                     /locus_tag="J8R83_002760"
     CDS             complement(<1..902)
                     /locus_tag="J8R83_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAZ9575853.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="J8R83_002761"
     CDS             1185..2153
                     /locus_tag="J8R83_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575854.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="J8R83_002762"
     CDS             2266..2544
                     /locus_tag="J8R83_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAZ9575855.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
BASE COUNT          837 a          466 c          524 g          732 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaa
//
LOCUS       DADQCX010000175         2543 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.183, whole genome shotgun sequence.
ACCESSION   DADQCX010000175 DADQCX010000000
VERSION     DADQCX010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.183"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..360
                     /locus_tag="J8R83_002763"
     CDS             <1..360
                     /locus_tag="J8R83_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575856.1"
                     /translation="GTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKRKLSHGYFVSYE
                     LYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGNICPGFMDQIIE
                     NESIESIENYVPVDLPK"
     gene            complement(533..715)
                     /locus_tag="J8R83_002764"
                     /pseudo
     CDS             complement(533..715)
                     /locus_tag="J8R83_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            702..899
                     /locus_tag="J8R83_002765"
     CDS             702..899
                     /locus_tag="J8R83_002765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575857.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(942..1517)
                     /locus_tag="J8R83_002766"
     CDS             complement(942..1517)
                     /locus_tag="J8R83_002766"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAZ9575858.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1672..2198)
                     /locus_tag="J8R83_002767"
                     /pseudo
     CDS             complement(1672..2198)
                     /locus_tag="J8R83_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT          812 a          443 c          403 g          885 t
ORIGIN      
        1 ggtacattat tttactatga ggaagttaga aatattgtaa aacatagaaa aaaagaaatg
       61 cctatacgtt gtccaaattg caatgaagtt attaagcgaa agttgtctca tggttatttt
      121 gtcagctacg aactatatga agaaagtaaa ataaatctga aaaaaaaacc aaaatactat
      181 aaaaatttga aaactggagc tattataact gaaaaagaat ttaaaaattt agtgactgaa
      241 gaagaaagca ggttttataa tttgtctggt aatatttgcc ctggatttat ggatcagatt
      301 attgaaaatg agtcaattga atcaattgaa aactatgttc ctgttgactt accaaaatag
      361 aaaaaataat cctgttttta cagtgaatta ttttaatttt gattttcaat aaaaatatat
      421 tacaataata atcgtaatag ctaatgaaac aatttctcaa tctttttacc actccaaaca
      481 gggagcgtca ataattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
      541 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
      601 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
      661 gaaactgctc ttttctgcgg ctgtatttct tgatttgttt attgaaagat tcgattgtag
      721 aaccagaagg aatggagaac acttttgaac tttacaacaa aactactgtt gataaattaa
      781 ttccaatttt agttccaact gatttaaatg gtcatgatgt tttacttcgt tttaacggat
      841 ttttaggtga ggattataga tacctaaaaa tttctgatcc tcaaccttta acagaataat
      901 aaaaaacgtg taatcaatta tttgattaca cgttttttat ttcaatcttc gttgtagtag
      961 tggttgcgac ataccgaaag gtaatcttca ttacctccta ctacaatctg ttcacctgaa
     1021 taaactggaa taccatcaac aatacgagca ttcattacag cctttttatt gcaaaaatgg
     1081 caaatagttt taatttcctc aattttatca gcaaatgtca ataatgcttc ggatcccttg
     1141 aagagattat tttgaaaatc attcttcaat ccatagcaaa ttactggtac ttcctcattc
     1201 attacgataa gtgatagatc aataatattc tctctactta aaaattgaga ctcatcgacc
     1261 aaaatacaat caacttttcc gtactgatca ataatctcca ctaattctcc gtacacatcc
     1321 atttcagaag taattgcaat agctggtttc gaaacaccta tacgactctc aacttttcca
     1381 aatcctgatc gagtatctat tgcgcttgtc attatgataa ctctcttccc ttgttcttca
     1441 taattatgag ccactttcag tagctcaata ctctttccac tattcattgt tccatatctg
     1501 taaaataatt gtgccattaa atttattccc ttcttttaca attcaattat tccttaattc
     1561 catctgcttt tatgcagctg ctcgtttatt ccttgatatg tctataacat ctactatccc
     1621 taaaaccaat ttataagcca ttagagatgg tattcctgaa catctctcat attgtttttt
     1681 gagtggtata tcatctgaaa aactgaagga atcatgaaaa tagcgacata cttatcattt
     1741 agagttctaa ctttaaatgc atttacttct tcagtcagca ctttagtcat gttggacatg
     1801 gtttggggcg tgtagtgatg cccatacatt ttctcaatca agtctgcgat ttccgacatg
     1861 gtaatacctt ttcggaagag gtgaatgacg gtctcctcta atgtgtcatt cgtccgtcta
     1921 taagcaggaa cagtctgttg cttgaactcg ccattgcggt cgcgcggaat ctggagatga
     1981 agttccccat actcggtctt gaccgtacgg tcataggagc cgttacgaga attacccgtg
     2041 ttaaaaccaa tgcgatcgta cttttcgtaa tcgaggaaag ccgttaactc cgttttgaga
     2101 agcgtattga cagctttttc caaatggaca cggaataatc cattcaaatc gcctttgttc
     2161 gctagagtct ttaggatttc tgtagtaaaa tcgttcatat ggaagtcctc ttttctgtga
     2221 atgtgttgtg gtaactctat tctacagaag ggacttcctt ttttctattt acacaaaata
     2281 ttttacactc tcaacaaaag tatcttcgat taatacttgc tcaagttatg tgcagctacg
     2341 aaaaagtagg taccgaggta ctttcttttt cgcagctttt tttggactta tgagaagtac
     2401 attcgctgga agaatacgat ataaaacgag ctttttcact aaagatatta atagagtgaa
     2461 agaaacaagc ttttgttgtc agttttttca cttttctaaa aatgaaaata aaaaattctg
     2521 gaagtggaga agaattttgc ttg
//
LOCUS       DADQCX010000176         2501 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.184, whole genome shotgun sequence.
ACCESSION   DADQCX010000176 DADQCX010000000
VERSION     DADQCX010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.184"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(117..707)
                     /locus_tag="J8R83_002768"
     CDS             complement(117..707)
                     /locus_tag="J8R83_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAZ9575859.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
     gene            1230..1391
                     /locus_tag="J8R83_002769"
     CDS             1230..1391
                     /locus_tag="J8R83_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575860.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLA"
     gene            1410..1904
                     /locus_tag="J8R83_002770"
     CDS             1410..1904
                     /locus_tag="J8R83_002770"
                     /inference="COORDINATES: protein motif:HMM:NF018154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin"
                     /protein_id="HAZ9575861.1"
                     /translation="MIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGYSF
                     ILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEMFI
                     NAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPIQYTSKELEE
                     ELHD"
BASE COUNT          898 a          374 c          413 g          816 t
ORIGIN      
        1 atgaatataa atagagtgta tcttctttga taaatgtcag aaaaagtgtg acaaataacc
       61 atcagtaaaa ttacttgtca tactattgat aaggagtatt taattgaaga gaatgattag
      121 gagaaaggat ctccgtactt tttatagtaa tcatagaatc caagtttgta tagacgaatc
      181 tttttttctc ttatttcttc tgtttcaaaa tggactgctt gaagaatcaa gtctgtgaat
      241 tctataggag ctgttccatt cgcagtaatc aaattacgat ctttcacagc ttgttgttct
      301 ataaaatctt ctttattctg ataattttcc gattctaacc aaggaaattg cgcatttccg
      361 gtgtgtttgt aaccttgcaa taatccgctc tgagctaaat aatcaactgc cccacaaata
      421 gcagctactg gtacgtctgt ttttaacaat ttatcgatta tttgatataa atgatgattt
      481 tttatgtccc atgaattgcc accgatcata ataaaaaggt caactttttc aggtatttgt
      541 tcgattaagt aatcgatttt tgtttttaat cctccaatgg aagtgacctc tgattggata
      601 gaagcagttt tgttttgcca tccctctttt tggtttagtg tgctagtaat ataagcacct
      661 tcccaatcgg catattcctc taatagaaac gtaatcgcag ttttcatttt caagctctcc
      721 tttactatct atgacaagga caacagtttt aacatacaga cattcattaa atttggatag
      781 cgacagcgaa aacaacaatt cttaagtttt agacagagta tacagacagt caacttaatt
      841 aaatacgaac taaataaaaa tgacaggtaa tcatttttgt ttaccagcat tataacattt
      901 tgcatacatg gatgacaaaa gaaccaattc ccacttgctt gagtacaatc ttaaaagaaa
      961 ctggaaggca aaaagtaatt atagaaacga aaaataaatc atatcgggca ctcagacatg
     1021 aaaacaaccc tagaaatata taactagtcc aatgaaaaaa aagcgaatgc cgtagaaaac
     1081 aaggattctg cgtacattca tatctcattt tgcgagcata tctgctatta ctgtgactaa
     1141 atgttaatat ggttaaaatg accgttatat tttttatata aatatcgtat aattagtatg
     1201 aatatagaag aaggaaagaa ggtgcaatct tggaacctaa agacaagtat ttagattacg
     1261 ctagggtcaa taaagataaa tttattgaaa caatcatcaa gggaaaaatc cctgatgatg
     1321 aaaaagatgc ggtattcatg gctggaagcc caggagcagg taaaacagag gttgcactag
     1381 gtttagctta aaattatgac aaccatgttg tgattgatgc ggactatttt agagcacaat
     1441 ttccagaata caatggaaag aactcaagtg tttttcagaa agcttcttct tggttagttg
     1501 aacaatcatt aaaatatgta ctggaacatg gctattcttt catactagag gatacttttg
     1561 ctatccttag tgcagagaaa aatattattc gagcccttaa aaataacttt cgcgttacga
     1621 ttttctatgt ttaccaagat cccaaagttg cctgggattt cactcgaaaa cgtgaactag
     1681 ctgaaggacg tcatgtgcca aaagaaatgt ttatcaatgc gttttttaag tccagagaga
     1741 atattgaaaa agtcaaaaat agacatcctg aagtagtcct tcacataatg attaaggatt
     1801 atcaaaacga catttctgaa gtgcattatg cagcagataa tattcaatta gtactaccaa
     1861 tacaatatac ttcaaaagag ttggaggagg aattacatga ctgagaaaga acaagtacaa
     1921 caaatcgtga agaagtataa taaaagtatc gctgatttat cagaaaacgc ctcagcgaaa
     1981 gaatttaaaa cagtaatgaa ttacgtagca gatgaagcaa atcgtaagca gcgaaaacta
     2041 gttgggttgg ataaataaat tttttaaacc atatccttgt aaagttgagt tttttatttt
     2101 aatgaattaa gactattaaa tagataatta ttgtaactta aaaaacacag ctaaaaatta
     2161 gttgtgtttt ttattaggtt tacttttctg gtataaaagg aactagctac tttttcaaaa
     2221 tttctaaatc attcaatatg tagcgcttac taaattattc gccataaaat tttataattg
     2281 gatcactcat tgttttacct aagtcatatt taagtaataa ccggtgtttt tacataagaa
     2341 gacttcgggt attttttagt ttgattagct ctgatatacc tataaagaat atgctaaggt
     2401 aagaatagta aaaattcaca tagatgaggt ataataatga tatttttata tattacagat
     2461 aacttgacac aaaatgagtt tttttcgatt tttcaagtta t
//
LOCUS       DADQCX010000177         2493 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.185, whole genome shotgun sequence.
ACCESSION   DADQCX010000177 DADQCX010000000
VERSION     DADQCX010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.185"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..435
                     /locus_tag="J8R83_002771"
     CDS             <1..435
                     /locus_tag="J8R83_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAZ9575862.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="J8R83_002772"
     tRNA            complement(759..842)
                     /locus_tag="J8R83_002772"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="J8R83_002773"
     CDS             1370..1870
                     /locus_tag="J8R83_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9575863.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="J8R83_002774"
     CDS             complement(2060..2404)
                     /locus_tag="J8R83_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAZ9575864.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT          777 a          478 c          413 g          825 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt tta
//
LOCUS       DADQCX010000178         2485 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.186, whole genome shotgun sequence.
ACCESSION   DADQCX010000178 DADQCX010000000
VERSION     DADQCX010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.186"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1016..1306)
                     /locus_tag="J8R83_002775"
     CDS             complement(1016..1306)
                     /locus_tag="J8R83_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575865.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1514..2205)
                     /locus_tag="J8R83_002776"
                     /pseudo
     CDS             complement(1514..2205)
                     /locus_tag="J8R83_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          735 a          459 c          348 g          943 t
ORIGIN      
        1 acatacttgc aaagtaatac tacaattcct aacataatcg tagaatttaa taatttccat
       61 agcataaagt gtttagaaaa gaacattaag aatagttcta taataattct tgaactccat
      121 gtcttataat gttctatcga agcacccaaa tagccaagtt catctaatct acttgcataa
      181 actacgtcat ccgctctcat agtcggcata tacatattaa agagtaaaaa gataccccaa
      241 atccctatta gtaacaagat cagttctttg ttattcgtta tttttctatt atgtttgttc
      301 atttttatac tccttcttat atttcctaat agagtataac atagctttaa gcattactta
      361 aagataactt aaaagttatc ttttaaatac ttaattgtta aataccttat ttgatgcaaa
      421 agaaatctac gatagtcaac aaaaaaattt tcattatatc cagaaaaatt tttcttagtt
      481 aaggacctat ggattgcagt aatgcagaat tcgtcgaata aactgccaaa gacatacaat
      541 catattgctt ttaaaattga cgaacaagat atagattcgt ttgtctcaaa aatccaaatg
      601 ttaggtttaa ctgtcgaacc aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac
      661 ttttacgact atgataatca cctcttcgag ttacataccg gtactctcca ggaacgttta
      721 aaatcctaca attccactac ctgagactag taatgactag tctcttttta tggcctctga
      781 tccccccatt gagcgaatac taatagggct tcgaattgat ctgttcaatc tttaagcaat
      841 atccctcaaa tgagtttgga aagtttagtg attcatcaca aatacttaaa tacatgtagt
      901 tatatataga ttgaggttct tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg
      961 catccatctt tccaaaacaa gcggctagga catttttgtc tcagccgctt gttttctagt
     1021 ttattctttc atcttgtcgg accttttttc ttgggtatag acttttctca tattctacca
     1081 caattttggg tttccctaac acatgatagg atctcacaac aaattgcttt ctattattat
     1141 aataacctgt aacgactaac ttcatccctt cgtctacttc agctaggaag ttcaaactat
     1201 gggaagcaat caaacaattg accccattta aactgaaacg gatcaacggt ctggcactaa
     1261 cttgcaaagt acggatctta tctactgttc catatttttt ctccataacc ttcacctcaa
     1321 taccattata cgaacataca ttccctttgt aaagaagaaa ctctgtttta tctttttgac
     1381 tttttgtcta ttacctttct taaaatcata ttggcacttc ctgcgaagat gaaggacatg
     1441 tactaaaaaa aagaggcagc agtatagatt actgttgctt ctttactaat ttaggtttac
     1501 ttgttaagaa agattattta cgcaaatgtt cttcaacaat ttgctgagat ttatcagctg
     1561 tatcttccac ttcatctttt gctttttcta acttttgaat atattgtttc aagcttgagt
     1621 tttcagcagt tgcttcgtct aatttctttt gtgtatctgt taactgattt ctacatttgt
     1681 tttttcttgt gtcagtgttg cgatttgttg attcaaacca tttacagtat tttgtaattc
     1741 tgaaagtttt gcttgtgctt cttgtagtct tgctgtccaa tctgcattca gatgattgat
     1801 ttcatcattt ttttggttga tctcatctag tttgacattg atttcatttt gtttgctttg
     1861 tagttgtgca tccttgctga ctaattgact ttctaagttt tgtttttctg ctgccgattg
     1921 atttttttgg ttttctaatt catttacttt tgtttggtat tcttggacat ctgcctttga
     1981 atcttgcaat gtctgttctt tttgtgctag tcgagcggta agatctgtaa tcgcttgctc
     2041 tttatctgtc aatgtatgat caagctgtgt cagattctca ttgattgtat caatatctgt
     2101 ctctccaccc cacaaaataa tttcatttgc gtaccgcgtg cctgtgtagc caattagaca
     2161 tagaaatgca acgacaatcc caccagtaat aaatttcttt ttcatttgca tagctcctta
     2221 atccaatact tttacatgct aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa
     2281 attacatatg taattttaat ataaatacta tcaaatactc atttaatcct ccttttttat
     2341 ctatttaaaa aatctttttt atagagaaaa atgcaggtta atactttctt aaataaatat
     2401 ttatggtgaa caaaaacaaa aaagcaagtt ttattaaacg taaccctttt catttcatag
     2461 attactgtat ttattacaaa aaacg
//
LOCUS       DADQCX010000179         2471 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.187, whole genome shotgun sequence.
ACCESSION   DADQCX010000179 DADQCX010000000
VERSION     DADQCX010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.187"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..418
                     /locus_tag="J8R83_002777"
     CDS             <1..418
                     /locus_tag="J8R83_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575866.1"
                     /translation="QEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLD
                     LSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMN
                     YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            632..1327
                     /gene="vanR"
                     /locus_tag="J8R83_002778"
     CDS             632..1327
                     /gene="vanR"
                     /locus_tag="J8R83_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAZ9575867.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1305..2459
                     /locus_tag="J8R83_002779"
     CDS             1305..2459
                     /locus_tag="J8R83_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAZ9575868.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          853 a          443 c          521 g          654 t
ORIGIN      
        1 acaggaagat gacatcattt atgttacaga cttaactcga atcactcgta gtacacaaga
       61 tctatttgaa ttaatcgata acatacgaga taaaaaggca agtttaaaat cactaaaaga
      121 tacatggctt gatttatcag aagataatcc atacagccaa ttcttaatta ctgtaatggc
      181 tggtgttaac caattagagc gagatcttat tcggatgaga caacgtgaag ggattgaatt
      241 ggctaagaaa gaaggaaagt ttaaaggtcg attaaagaag tatcataaaa atcacgcagg
      301 aatgaattat gcggtaaagc tatataaaga aggaaatatg actgtaaatc aaatttgtga
      361 aattactaat gtatctaggg cttcattata caggaaatta tcagaagtga ataattagcc
      421 attctgtatt ccgctaatgg gcaatatttt taaagaagaa aaggaaacta taaaatatta
      481 acagcctcct agcgatgccg aaaagccctt tgataaaaaa agaatcatca tcttaagaaa
      541 ttcttagtca tttattatgt aaatgcttat aaattcggcc ctataatctg ataaattatt
      601 aagggcaaac ttatgtgaaa gggtgataac tatgagcgat aaaatactta ttgtggatga
      661 tgaacatgaa attgccgatt tggttgaatt atacttaaaa aacgagaatt atacggtttt
      721 caaatactat accgccaaag aagcattgga atgtatagac aagtctgaga ttgaccttgc
      781 catattggac atcatgcttc ccggcacaag cggccttact atctgtcaaa aaataaggga
      841 caagcacacc tatccgatta tcatgctgac cgggaaagat acagaggtag ataaaattac
      901 agggttaaca atcggcgcgg atgattatat aacgaagccc tttcgcccac tggagttaat
      961 tgctcgggta aaggcccagt tgcgccgata caaaaaattc agtggagtaa aggagcagaa
     1021 cgaaaatgtt atcgtccact ccggccttgt cattaatgtt aacacccatg agtgttatct
     1081 gaacgagaag cagttatccc ttactcccac cgagttttca atactgcgaa tcctctgtga
     1141 aaacaagggg aatgtggtta gctccgagct gctatttcat gagatatggg gcgacgaata
     1201 tttcagcaag agcaacaaca ccatcaccgt gcatatccgg catttgcgcg aaaaaatgaa
     1261 cgacaccatt gataatccga aatatataaa aacggtatgg ggggttggtt ataaaattga
     1321 aaaataaaaa aaacgactat tccaaactag aacgaaaact ttacatgtat atcgttgcaa
     1381 ttgttgtggt agcaattgta ttcgtgttgt atattcgttc aatgatccga gggaaacttg
     1441 gggattggat cttaagtatt ttggaaaaca aatatgactt aaatcacctg gacgcgatga
     1501 aattatatca atattccata cggaacaata tagatatctt tatttatgtg gcgattgtca
     1561 ttagtattct tattctatgt cgcgtcatgc tttcaaaatt cgcaaaatac tttgacgaga
     1621 taaataccgg cattgatgta cttattcaga acgaagataa acaaattgag ctttctgcgg
     1681 aaatggatgt tatggaacaa aagctcaaca cattaaaacg gactctggaa aagcgagagc
     1741 aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt tatgtacttg gcgcacgata
     1801 ttaaaacgcc ccttacatcc attatcggtt atttgagcct gcttgacgag gctccagaca
     1861 tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt ggacaaagcg tatcgactcg
     1921 aacagctaat cgacgagttt tttgagatta cacggtataa cctacaaacg ataacgctaa
     1981 caaaaacgca catagaccta tactatatgc tggtgcagat gaccgatgaa ttttatcctc
     2041 agctttccgc acatggaaaa caggcggtta ttcacgcccc cgaggatctg accgtgtccg
     2101 gcgaccctga taaactcgcg agagtcttta acaacatttt gaaaaacgcc gctgcataca
     2161 gtgaggataa cagcatcatt gacattaccg cgggcctctc cggggatgtg gtgtcaatcg
     2221 aattcaagaa cactggaagc atcccaaaag ataagctagc tgccatattt gaaaagttct
     2281 ataggctgga caatgctcgt tcttccgata cgggtggcgc gggacttgga ttggcgattg
     2341 caaaagaaat tattgttcag catggagggc agatttacgc ggaaagcaat gataactata
     2401 cgacgtttag ggtagagctt ccagcgatgc cagacttggt tgataaaagg aggtcctaag
     2461 agatgtatat a
//
LOCUS       DADQCX010000180         2464 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.188, whole genome shotgun sequence.
ACCESSION   DADQCX010000180 DADQCX010000000
VERSION     DADQCX010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.188"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            164..2317
                     /locus_tag="J8R83_002780"
     CDS             164..2317
                     /locus_tag="J8R83_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAZ9575869.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          844 a          428 c          545 g          647 t
ORIGIN      
        1 aaaaatagtt ggatatgtaa ctttaagtga ttgctgtgaa acaaaaagtt gattttatct
       61 tgaaattagg taaagaattt cttgctccgc ccattttttc ttttttatta agaagttttt
      121 gggtacaatg aagcatgaat gtaaataggc ggaaggatag gaaatgatga aagattttat
      181 gaaaaaaata ttaaatactt cttggttaga aaaaataaga aaaggtgcac aagaacctaa
      241 gaacaaaacg tttcgccggt cccatgttcc ttttcgctta aattttcttt ttttcattat
      301 atttacgtta tttgttgcgt tgattgctag attgggttat ttgcagatcg tgaacggcga
      361 agagatggag gcgcgagtga agtctacttc tacgattacg gtccaagaaa gtactcctcg
      421 cggaatgatc tacgactcca caggaaaagc tttagttacg aataaagcga atcaggccat
      481 cacatatacg agaggaacac aagttacggc taaagatttg cttgaaatcg caacgaagct
      541 gaactcgctg atcgatgttc cggtagatga aaatctgaca gatagagata aaaaagattt
      601 ttggctggct gatcccaaac atttgaaaga agccacaaaa agactttcgg caaaagaaaa
      661 gcaattaggg aacagcgaac aatatagtgc gatggtcaat aaagtcacag ctgatgagat
      721 taatttaaac gaggagcaat taaaaattgc taccatcttt aaacggatga atagtgcata
      781 tgaattaaac actgtctata tcaaaaactc tggtgttact gatcaagagt tagctgttgt
      841 ggcagaacgc gcttctgaac ttccaggagt ttcgactggc acagactgga cacgagaata
      901 taatgcagca agttcactga aaagtattct tggcagtgtg acgactgaaa agcaaggact
      961 tccagcagat gaagcagaga aatacctagc aaaaggttat tctcggaatg accgtgtagg
     1021 acaaagttat ttggaaaaac aatatgaaga tgtcctgcaa ggaaccaaaa cccaatatga
     1081 agtttccctt gataatgaag gaaatgtttc gaatcaaaaa gaaatcttct ctggggaaaa
     1141 aggttctaat ttaatgttat ctatgaatgc agaattccaa tcaaaagtag aagaaatttt
     1201 gaaaaggaat tatcaaacat tgatcaacaa cggcaaagca cagtattcgc ctggtgctta
     1261 tgcagtggct atgaatcctc agacaggaga agtgctagca atgactggtt tcagtcatga
     1321 acaaggttcc aaagaaatca ccgagaatgc tttaggcacg attactagcg cctttgatcc
     1381 agggtctgta gtcaaggctg gtactttgac agcaggctgg gcaagtaacg cgatcagcgg
     1441 aaatcaagtt ttgattgatg agccgattcg tctgcaaggt gcttcagaaa aaagctctgt
     1501 ctttaatcga agcggacaag ttgctcttga tgcagtcaaa gcatcggaat tgtcttctaa
     1561 tacgtatatg atcaaagtgg cgttaaagat gttaggacta gactatacac ctggaatggg
     1621 actacctagt ttagatgaag aagctaaagc ttatcagcaa ttgagagact ctttcaaaga
     1681 gtttggtctt ggtacaacga ctgggatcga tttgccgaat gaatctcctg ggatctcacg
     1741 ttctgttgat tatatgaaga agttcaatgc ggataatggc aaagaatggt atgctccagg
     1801 taactttacc gatttggcat ttggacagtt tgacacatat acaccaatcc aattagctca
     1861 atatgcttca acagtcgcta atggcgggaa acgagtacag ccgcacctag tcaaagcgat
     1921 ctatggcaat gacgaaaatg gaaacttggg tgaagtgaag aaagaaattg gcacaacagt
     1981 agaaaatacg gtcaatattt ctgcagaaaa tatggcgatc ctccgtgaag gattccacca
     2041 agttgtccat ggtaccgatc cttacacaac agccaaacca ttagccagtg cgaaaatgga
     2101 cctttccgca aaaacaggga ctgcagaaac ggttgcggaa ggtcatccag atattgcgac
     2161 agtcaatagt aatatcgtgg catacggacc aacagacaat ccggaaattg ccatcagtgt
     2221 tgtcttgccg aacttattag acgaacaaga ccacataaac ttgacgattg ctaaagaaat
     2281 aatggacgcg tattatgata tgttcatggc aaaataaaaa agaggtcgtg aaaaagccgc
     2341 ttagtttcga gtatgaagaa aaattttgtg aaaatagctt ctcacatttt tgcttaaatt
     2401 tgacttcata ccgagaaact ggcttttgaa caccgtttac tcggcaaaaa aggttgtgac
     2461 aaaa
//
LOCUS       DADQCX010000181         2387 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.189, whole genome shotgun sequence.
ACCESSION   DADQCX010000181 DADQCX010000000
VERSION     DADQCX010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.189"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(491..1783)
                     /locus_tag="J8R83_002781"
     CDS             complement(491..1783)
                     /locus_tag="J8R83_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAZ9575870.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2057..2317)
                     /locus_tag="J8R83_002782"
     CDS             complement(2057..2317)
                     /locus_tag="J8R83_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575871.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          788 a          448 c          361 g          790 t
ORIGIN      
        1 atattataaa ttcacatgat tatcgaattt tattaagtta gtttttcttg taaatctctg
       61 ttcccaatga aactcgagac acttatttta aagaggaaac aatgtggtat ttaaatagcc
      121 ctcttgtatg ggctactctg tgatacttat tagccattaa actattttac ccacatagca
      181 tatattttga aatcgttcat tccgtaaatt caactaaata tgcctaaaaa aataaaaaat
      241 ctaagataga ataagattta ttcagtctta gatggattta tagcaacttt ttcgtaacaa
      301 ctttaaaaaa tacgaaaaga aagagctgtt ttactctgac tacgttgcta aattgtcgtt
      361 taatcattca tttaaaccaa atcttttttt atagaattcg ttttaatcct cctgaatcca
      421 aaaactatga aaaccgtaat taaatagtta agagttttta accaccataa ttctctcggc
      481 tattttgaaa tcagataaat tttgatcgga cacatagttg aataaaccta ccgttgttac
      541 ggaaggtaaa tcgcatactt ttcattctag aggagaaggt ctcgttgatc attaactgat
      601 taagcaccat agcccagttt tgaattcgac cacctgacca cttcgcgtgt aattctttcg
      661 tgcgtaaata aagtagtttt aggagtgcat tctcattaga gaacgctcct ttttttgtga
      721 cttttctgaa gctggagtgg acactttcaa ccgcattggt agtgtacata atttttcgaa
      781 tggcactacc ataatcaaat agttgttcaa catgtgcaaa gttccgtttc cagacatcta
      841 cagcaccaga ataatgagac caccgatttt gaaaactgtc aaaagcagca tgtgcagcgt
      901 ttagagaaga agcaccgtag aactttttca tatctcggca gacttcctta tagtccttac
      961 ttggaatata gcgcaatgca tttcgaacaa gatgaacaat acagcgctga acaattaccg
     1021 atggaaagat cgcttttgcg ccttcttcga ggccagaaac accgtccatc gaaatgaaaa
     1081 agacatcttc gacaccacgt gctttcagtt catcaaatac ttgcatccag cgatttttag
     1141 attctgtttg atttaaccat aatcctaaaa tctccttatt tcctttgaga tcatagccaa
     1201 gaatggtgta tacagcatat tctttggctt cataattttc tcgtaaagta acatacatac
     1261 aatcaacgaa tagaaaggca taacactttg ctagggggcg ggcttgccat tcttccaatt
     1321 caggaaggac agcgtcagtg atatctgaaa tcatttcatg ggaaatatca aagccataaa
     1381 tagcttcgac ggttgcggca atatctcgtt gactcattcc tcgtgcatac atggaaagaa
     1441 ccttcccttc gatgtcggag acatctcgtt ttctcttagg aattaactct ggttcaaagg
     1501 aagcttcccg gtctctagga acatcaatag ctacttcacc aaaactggtt ttaagcgttt
     1561 tagttccata gccatttcga cggttatcgt gttccttagg ctctttagaa tgggcatcat
     1621 aacctaaatg attattcaat tctccttgaa gcattttttc aaaaaggggc ccaaacacat
     1681 ctttcaaagc atcttgcatg tcatcgacag attcaggttg ataggcattc agaatggatt
     1741 cagctaactt ttcggcatca ggatttcttt tctttctagc catcgtgtaa tcacctcttg
     1801 atcttattgt agaaaaagaa aaaccgcgaa gcaaccacct gcctaggatt aatggttact
     1861 tacacggttt atattacact ctcatcatta aaaaagtatc tttcgatatt actaaacaat
     1921 gaaattatct atttgaaatt taaatctgat aatatattga gtgttccaat gagggctttg
     1981 atcctattat ccatatcttt ttcagtttta atattgatac acattataag aaaaagaaac
     2041 ttttggttaa tttatttcat cccagtgcaa aatataaaaa agtaaaatag accataggca
     2101 atagattaac aattaatata atacaagcaa atattctatt cattgtattt ctgctttcaa
     2161 aaagttctaa tattgaaagt ataattccac aaatgcctat aataagtatg ggaataagat
     2221 tagaaaataa caccccgagc caatctgtga aaattactat atttactaat atccctatta
     2281 acatacctat catatttatt aaatcaattt ttttcattag atatttctcc tttattaaat
     2341 ctgaagtact tatattaaaa taattctaaa ctatttacct caaaaag
//
LOCUS       DADQCX010000182         2385 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.190, whole genome shotgun sequence.
ACCESSION   DADQCX010000182 DADQCX010000000
VERSION     DADQCX010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.190"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(14..259)
                     /locus_tag="J8R83_002783"
     CDS             complement(14..259)
                     /locus_tag="J8R83_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575872.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(276..1127)
                     /locus_tag="J8R83_002784"
     CDS             complement(276..1127)
                     /locus_tag="J8R83_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAZ9575873.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            1293..2297
                     /locus_tag="J8R83_002785"
     CDS             1293..2297
                     /locus_tag="J8R83_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAZ9575874.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT          757 a          406 c          479 g          743 t
ORIGIN      
        1 cgttccattc tttctatttt ttcggtatca aggcaaaaac aggtagttca ggtgaataaa
       61 tgacttcatg ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt
      121 cttcgatgat ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt ttctctgcat
      181 cgatcaaaaa gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag agagaattca
      241 agcgttcgat tggatccata aaatcacctt tcgacttaaa attgggtagt atctgggtct
      301 tttgctttgc cgactacacc atctaactga tcgatttgtt tcatttcttc ttctgttaat
      361 tcaaaatcaa ataattcagt attttctttg attctgcttg gtgtcactga cttaggaaga
      421 ggaaggaatt cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt
      481 gcttcagcga tttgtttcat ttcaggcaca tcgaagattt taccagtgcc taatggacta
      541 tatgcttcga ggatcatatc atgttttttt gcatactcaa ctacagttgt ctgtaattcg
      601 cctggtgcaa ggaaaacttg attgaccatc ggcataattt ttgctgtttt tgctagtgta
      661 tctagatggt ggggtaagaa attgctcaca ccgattgctt tgattttacc tgcttcatac
      721 agttcttcaa atgctcgcca tgtatctgca tttgcttgtt cccaattatc acgaaaagca
      781 acagggtttg gccagtggat caaaaacaga tctaaataat ctgtttggag cttcttcaat
      841 gattcttcaa aagaagacat cacaagttca tagctgtggt ttgcattcca taattttgtt
      901 gtcaagaata tctcttctct aggaattcca ctttccttaa tcgcttggcc gacgctttct
      961 tcattcttgt atccttgggc agtatcgata tggcgataac ctgcagccag cgcttcttta
     1021 acagaggaaa cagcgacatc cccatcaggt gtttgccatg tgccgaatcc tactaccggg
     1081 atttcgtaac catttgatag acgataagtg cttgttaatg aattcatact ttcagctcct
     1141 tttttattcg ttcaactata agtgtagcgc atttttcgaa aaaaagaatc cattttgttt
     1201 ctactcttga aatttttgtt taaaagaaaa tgattttgat tctggtattt ttgatttttt
     1261 ttccgtaaac taagacagaa gggaatgaga aaatggatat ctatttaaaa aaagcaattc
     1321 tgcatattat tgacagagaa actggttctc cagtcttttc acaaaaagag ctggatctga
     1381 caaaagaata tattcgtgat tttcttcaaa agaagatcca aaaaatctct tctgctcaaa
     1441 caaaaactgg acaactagca gaagaaagca tgatcgttga atcacttaaa atcgctcaag
     1501 aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa
     1561 gtgaagaagc acctagtgca gatgtatttg ttgtcttgta tgaattagat acagtgatgt
     1621 acttatcttt attgaaagtc aattatcgtg aggcttacac tcactttgtt gaagcagacg
     1681 aagcagggat cgacaaccgc ttgattttga atcgagcaat tctaggggcg aaaacacaaa
     1741 aagcagatga agcattcgct gtgaatttga ctgattggac ctacgaatta attgaaaaaa
     1801 aatatgagtt ttctggcaaa aaagagcttt atttttctgg aagagtgatc gaaagtgttc
     1861 ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa agtagccaag catcttggaa
     1921 aaaaatttga gacagaagaa tttgatatca tggctgattt gaaagaagct gtctatgata
     1981 cgatagaaga aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa
     2041 acatcacggc aaaaatggct tttaaagaag aagtacaaga gcaaggattt gtcccagaag
     2101 cacctcctgt aaaagaagta caagaaattt ctgagaaaaa atttggaaaa caaaaattca
     2161 agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac ccagatttga
     2221 ttgaatttgt gaataatccg gatggtacga tatccgtgat gatcaaaaat gtggatgaag
     2281 tattgaatcg tttataaaaa tgactagaat attaggtgtt caagtaccag tgatcagtta
     2341 aatgaattgt gtcaagagaa ggatcggaaa agacgaatat aacaa
//
LOCUS       DADQCX010000183         2348 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.191, whole genome shotgun sequence.
ACCESSION   DADQCX010000183 DADQCX010000000
VERSION     DADQCX010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.191"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(138..428)
                     /locus_tag="J8R83_002786"
     CDS             complement(138..428)
                     /locus_tag="J8R83_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575875.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="J8R83_002787"
     CDS             complement(546..806)
                     /locus_tag="J8R83_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575876.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="J8R83_002788"
     CDS             complement(943..1356)
                     /locus_tag="J8R83_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAZ9575877.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="J8R83_002789"
     CDS             complement(1812..2297)
                     /locus_tag="J8R83_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575878.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
BASE COUNT          860 a          381 c          368 g          739 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaa
//
LOCUS       DADQCX010000184         2293 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.192, whole genome shotgun sequence.
ACCESSION   DADQCX010000184 DADQCX010000000
VERSION     DADQCX010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.192"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..1598)
                     /locus_tag="J8R83_002790"
     CDS             complement(51..1598)
                     /locus_tag="J8R83_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAZ9575879.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="J8R83_002791"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="J8R83_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAZ9575880.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="J8R83_002792"
     CDS             complement(2043..2237)
                     /locus_tag="J8R83_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575881.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DADQCX010000185         2286 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.193, whole genome shotgun sequence.
ACCESSION   DADQCX010000185 DADQCX010000000
VERSION     DADQCX010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.193"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(22..837)
                     /gene="thiD"
                     /locus_tag="J8R83_002793"
     CDS             complement(22..837)
                     /gene="thiD"
                     /locus_tag="J8R83_002793"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAZ9575882.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            1131..1406
                     /locus_tag="J8R83_002794"
     CDS             1131..1406
                     /locus_tag="J8R83_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575883.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            1833..>2286
                     /locus_tag="J8R83_002795"
     CDS             1833..>2286
                     /locus_tag="J8R83_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAZ9575884.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT          742 a          436 c          343 g          765 t
ORIGIN      
        1 ctttttcaca acttctttct tttactctaa ttcaccagct gcccaatgat tgatggggcc
       61 atatttgtgc cctacattta tttcttcacg aattgcacgg tttacatagt cttttgccaa
      121 tcggatcgct tgttcaactg tttttccttt cgctaactca gctgcaatac atgcagatag
      181 cgaatcgcca gttccgttga tccggtcggt aggataaaat ggtgcattta accaaaatga
      241 ttttcctgat tcgaacaata cgtagtcatt gactgtttct tgctgcgcat ttttagcatg
      301 atgtcctttg atcataacgt tttttgcacc catatcttgc agttcttttg ctgcttgcac
      361 aaaatcttct tcagctgcta atgtccgtcc agtcagcttt tctgcttcat aaaaattagg
      421 tgtcagtact tcggccaaag ggacaagctt ttctttcaag ctttgcaaag cagattcttc
      481 tagtaaaaga tttccatgtt tcgttacgat tacgggatcc acgactaatg gtccaaaatc
      541 atatttttgg taatttttta caactgtctc aatcaacttt gaatctgcta gcatacctgt
      601 tttagctgca cgtatttgaa agtccttcgc aatcagttca aattctttgt cgataaaatc
      661 tgttggcaat gtcacacttg ctccgattcc gtaagaatta cctgcaacac atgcggtcat
      721 gacagaaaca ccgtaaacat ttcttgtaaa gaatgtatgc atatctgctt gcatccctgc
      781 gcttccatcg ctatctgatc ctgcgatcgt cattgcttgt acatactgat cttccatcaa
      841 atcgattcct ccatttttat aaaaagattt ttcataatac tgttactgtt tctatcatat
      901 gtttttcaaa gtatccctca gtaaatatac cactaccttt tcttggtaat caaatttatt
      961 tgaaaaaaca tttgcaataa atcagaaaat agtggtcgtt tatttgtatt cgctattcta
     1021 ataataaata accactattt gatttatata tatttcagta tccttcttgt tttcatataa
     1081 ccaaaggcgc tatgatttcc atatgaaaaa aataaagtca ggtgaaaaaa atgaaacttg
     1141 aggataaaaa agtcattttg aagaaaatca aacgactacc agaccaaata gatggctata
     1201 cgatctgttc tttcaaaaaa gacaggagta taaaagctta tacgcaaaac acagaaaaag
     1261 gaataatcta tttcctacat gaagaaggtt acgataccca aacctttatg tttactgaaa
     1321 aaaaagaatt tcataaacag atgaaaaaac tgattgaaaa agaatttcca agaagtcata
     1381 aactctatgt gaatcagcaa ttttaacttc taactgttct ttattaatta aaaatgttct
     1441 gtaataaaat aaaactttat aacaactata acaaaaccga atgcaaaaca gaagttctat
     1501 aagttataat catagttgtt aggtgattca tctagtaaaa acaccagatt tcaaatttca
     1561 cacaatttaa actagatcaa tcatcaacct tcttcaaatt gttagaaccc tttcccgagg
     1621 agctgcagca taagcaaaaa aacaaacagg aagccaaatg gctaagacat tttttctatt
     1681 agtctagttg tttctcgtcg caagtttaag actttagaaa gttatttcta atgatgtttg
     1741 ggttgttttg atcaatgctt atgcacagct ccttacctat tatttatctc aacagatcta
     1801 acaaattaat ggactattta aggagttttt ttatgcttac gatctattct tctcgcacac
     1861 atagttacca tctgatggca aactggctga aagaccatca aatgccttac agagaacgaa
     1921 ttttcacacc taaacagcct ttaacaagga aagagatatt ttatttattg tcattaacag
     1981 aaaacggatt tgacgatcta ttagctaaac gctcgattga ttataaaaat ttgaaagacc
     2041 aaatcgacca atgtacgacc tcagagcttg tcgatctgat cgtctcgcat tttactttgt
     2101 tacaacgtcc catcattact gacggaaaga aattattagt cggattcaat gaagatagca
     2161 tgcgtctttt tatccctgta caatggcgca gaagtcaact gaaatctgtc tataacgatt
     2221 ttacatgggt aagcaatcta gaaaattcta cggatttaga tgatgaattt ttaaattatt
     2281 atatat
//
LOCUS       DADQCX010000186         2279 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.194, whole genome shotgun sequence.
ACCESSION   DADQCX010000186 DADQCX010000000
VERSION     DADQCX010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.194"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            88..1950
                     /locus_tag="J8R83_002796"
     CDS             88..1950
                     /locus_tag="J8R83_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9575885.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            1950..>2279
                     /locus_tag="J8R83_002797"
     CDS             1950..>2279
                     /locus_tag="J8R83_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9575886.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          817 a          340 c          450 g          672 t
ORIGIN      
        1 tataagttgc acttagttaa gtgcaaacat ttcatattgt cgttagttta gaaaacgctt
       61 atattagcaa tgtaaggaga gatgataatg cagcagctaa caaaaagaga aaggcagctt
      121 ttgatttact tggtggaaat gtctgaaccg gtaacaatca aaaagttggc tgaaaaagaa
      181 aatgttagtg ttcggacgat aaaatacgat ctagatgata taagagagtg gctgaatgag
      241 cggaagcaag tcctatatag caaacgtagt cagggaattt ggatgaatat tagtagctct
      301 gatcgaatca aattaaaaag cgaattgatg gatgttaatc gttttgaaat atttgcagat
      361 caaagtctcc gaatcaaacg tttactaatt atgcttttag taacaaaaga agctattact
      421 ggaatgaaaa tggccaacgc attagatgtc agcaaagata cgatcatgaa tgatttagat
      481 gtgctggaaa ataattttct taaggaagga ttgaccttga atcgtcaggc gcgaaagggt
      541 ttttggatca taggagaaga acgtctagtt cgattaacga ttgaagagat tcttcaaaaa
      601 gagttcacgg attatgacat ttataaatta atgtcattgt tattgaatgg cggtgagact
      661 gaatactttg aaatgtattc tgctactgct acacctatcc aagaggtatt taatcaagta
      721 atcattcgaa tgcgacactt actggaattt gaaaatctag agaaactgaa ttacgcggaa
      781 ttactaaata ttctgattcg agtgacaatt gctaccgttc gcttacgcaa agaggctacg
      841 attggtcgtt atcaattggt tgctgaacaa gaattagaca aaaacgatct ttcttatcgc
      901 gtcatgcagc aggtctttga ttattatcag ttgccactgt tcgaggatga atatcattat
      961 atctatagtg atacattcga cacgattcac cagcaagacg tcatgaaact agttgagaat
     1021 gtgatttata aagtaagtaa agcaatcaac cattcttttt atcaagatcc acaattgttg
     1081 acgaatctgt atgctcattt atccatgcga ttatcgagaa agaaaaaatt tgtcaatgaa
     1141 tataatcctt ttaaagaaga tatcaagcag aaatacccgg aattatttga tgcgatcaag
     1201 caagcagttc gacaagaaat aagtgaacaa aatattctga tcaatgattc tttcgtggca
     1261 tatattgcct tacacttttt ggtttcctac gaaagagaag aagatctacg aagcgttaga
     1321 gccgtctaca tttgttcaac agggttgggt gtgactagtc tgatcaagca aaagatcaat
     1381 gaagaattaa ataatatcac tatcgtggca tttgcttcag tattgaatgc gcaagaaatg
     1441 attgctacca aagatcctga tttggtgatt agtatttttc caattaatgg catcgatcgt
     1501 cctttcatca aagtccatcc attacccact gaacaggact tgaaaaaaat tcaacaaata
     1561 ataaaaaaaa tacttgcttc ttccaatcag caggaaaggc ataacttgaa tcttagagaa
     1621 acgtccatca ataaagatac tttagaagac tttagcaagg aattgatttt gaaagcttat
     1681 acgatttatg aacgtttact tgtcattttg gaagcagaat tgatccaaga atatcgagaa
     1741 gcttttttgc ttcatgtatt cttaatggtt catcgtatca catttgatca acaatatatg
     1801 gcagaaggtc gtcaagtaga ccagattatt ttagacaaag gaacactggt aggaaaaatc
     1861 gaagcagttt ttgcagaaaa taatttagga atcaatcagt cagaaatcag tgcattattc
     1921 tcatatataa aagaaggagc gtcaagttag tgaaaatgtc agacgaggct ttaaaaatta
     1981 tcgaggaaag tcaaaatcgg gaaaagttaa aacaagtgat tgatctaatt gaagagcgat
     2041 tagtagaaca tgctattgta ccaaccgagt tgcagtggac cattctaatt aatcacttga
     2101 atgagatgct gaaacgttct caaagaaagg aaacgattcc cgtagtcgat cgggatttgt
     2161 tcaaagaagt atccaaagaa gccataacta tttctgatga aatagttaga agtatcggta
     2221 atttaaccga tgatgaaata tatgttttgt cgattcattt tgaaacagca aaaaataat
//
LOCUS       DADQCX010000187         2273 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.195, whole genome shotgun sequence.
ACCESSION   DADQCX010000187 DADQCX010000000
VERSION     DADQCX010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.195"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..148
                     /locus_tag="J8R83_002798"
     CDS             <1..148
                     /locus_tag="J8R83_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAZ9575887.1"
                     /translation="LNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYI
                     NFDK"
     gene            309..1478
                     /locus_tag="J8R83_002799"
     CDS             309..1478
                     /locus_tag="J8R83_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAZ9575888.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
     gene            complement(1803..>2273)
                     /locus_tag="J8R83_002800"
     CDS             complement(1803..>2273)
                     /locus_tag="J8R83_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9575889.1"
                     /translation="NISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKIT
                     VNNYILDENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKI
                     SNMDKIFDVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT          814 a          362 c          322 g          775 t
ORIGIN      
        1 actgaatcaa gaagtacgca gaagagaaaa gattattcgc atcttcccca atcaaacatc
       61 agccaatcgc ttaattggag ccgttcttat ggacctgcat gatgaatgga tttattcttc
      121 aagaaaatac atcaattttg ataagtagaa attgtaaaaa cattgtatag cattttacac
      181 aggagtctgg acttgactca aaaagatagc gtaaaatatt ttgtgtaaat agaaatttag
      241 ggtagaaaaa aaagtccatt ctgtaaaatt aaagttacca cacagaaatt ttataggagg
      301 actttctcat gactaaattt actatagaaa ttatgcaaac actactcaat aaaggggatt
      361 tagatgaatt atttcaggat catttagagc gagcgattaa ttcacttcta caagcagagc
      421 taactgcttt tttagattac gaaaaatatg atcgaaatgg attcaattca ggaaattccc
      481 gtaacgggaa ttattcacgt acatttaaaa cagaatatgg cgagttgaat ttaactattc
      541 ctagagatcg gaatggcgaa ttttctcaac aaacactacc agcatataag cgaaccaatg
      601 attcattaga aacgaccatt atccaattat ttcaaaaagg cattactatg gctgaaatct
      661 ccaaattaat tgaaaaaatg tatggtcacc actatacgcc acaaacaatc tccaacatga
      721 gtaaattggt ggctgaagat gttttagctt ttaaagaaag aacgttagaa gccaattatt
      781 ccgttatatt tatggatgcg acgcatatcc ctgtgaagcg acagactgtt tcgaaggaag
      841 cagtgtatat tacgattggt attcgtttgg atggaaccaa agaagttctt gggtttacta
      901 ttgccccaac tgagtctgct tatatttgga aagaagttct tcaagatctt agaaaacgtg
      961 ggttagaaga agttttatta gtagtgacag acggattaag ctgtattgaa gaaagtatcc
     1021 atagtgtgta tccgaatgcc caatttcaac aatgttgtgt gcatgtatct agaaatatcg
     1081 ctcataaagt tcgtgttcga ggtcgaaaag aaatttgtga ggatttcaaa ttggtttacc
     1141 aagcgaattc aaaagaagag gcattggatc acatcgactt tatgactagg aaatggaaaa
     1201 agcagtatcc aagagtcgtc aatttactct tgaatcctgc cctattaacc ttttataatt
     1261 tccctcacgc catcagacga acaatttatt cgacgaacct gattgaaggc tttaataagc
     1321 agctaaaacg atatactcga agaaaagaac aattccctaa tgaagaatct ctagagagat
     1381 tcttcatttc tcaatttaat caatataacc aaaaattttt aggtagaatt cacaagggat
     1441 ttaaagaaat tcaggataca ttagagtcga tgatttaact gtaattaaca gaatggattt
     1501 tccatttaca cataattctt gacgctacca taatctaaat aaccatcata ttcatctact
     1561 acttatataa ttgagtttta ttaaactttt taagtttcta ttctatcaaa tatttaaaca
     1621 atctctgcat ccgaaaagac tacctcgtat agttttacta acaatatttt tattagcgtg
     1681 ttcaaatcct gatttcttgt atcaattatt ttctgttcac tttcaataag aaaaaagtct
     1741 ttacttccat ggataataat aagtctctat ttttcaataa ctattgcaaa attatatctt
     1801 aattaagaaa atatttttat tttaaagata aaaaattctt catcctgcaa tactttatat
     1861 tctatattgt aattattcag aatattactt acaatatata aacctaatcc attactattt
     1921 tccttattta aatcaaattt aacatcaaat attttatcca tattcgaaat tttattgtta
     1981 ccgtatgaat tctctatata taaccaatca ttaactatcc caatattaat taccccattt
     2041 acatcagtat attttaccgc attactaatc aaattagata gaataatctt taaagctgtt
     2101 tttcctatat aaacattctc gtctaatata taattattga cagttatttt cttttgattt
     2161 gctaatattt catacttttt taatatgtct tctaatgtat catttatttt caaatattct
     2221 tcatcattat tcaaattttc tatagaatga actgataata tttgagaaat att
//
LOCUS       DADQCX010000188         2246 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.196, whole genome shotgun sequence.
ACCESSION   DADQCX010000188 DADQCX010000000
VERSION     DADQCX010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.196"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            126..425
                     /locus_tag="J8R83_002801"
     CDS             126..425
                     /locus_tag="J8R83_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575890.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            690..1565
                     /locus_tag="J8R83_002802"
     CDS             690..1565
                     /locus_tag="J8R83_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575891.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            1562..1780
                     /locus_tag="J8R83_002803"
     CDS             1562..1780
                     /locus_tag="J8R83_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575892.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            1767..>2246
                     /locus_tag="J8R83_002804"
     CDS             1767..>2246
                     /locus_tag="J8R83_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575893.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     "
BASE COUNT          879 a          249 c          433 g          685 t
ORIGIN      
        1 atctggagta tgatacttta ttcttataaa tacaaataaa tacatttttt tacgcaattt
       61 gtatttattt gtacttataa aggtagagga gttatagaat aattaattaa aaaggagagg
      121 tttttgtgga agcaataaaa ttaatgattt cagaagaaca ggaggaaatg tttctaaagc
      181 agttttatca aattgctaca aaagctattg aaaaggctca agaaaatgcg gggatgacaa
      241 gggaatatct caatcaaaaa gaaatggcgg aatacttaaa tgtgagtgaa aactttttaa
      301 aaaatgctgt gagaaatgag ggattgcccg tagttgaatt aggggcaaga aaattttatt
      361 cgaaaaaggc agttaatgag tttatgtttg ctcgaatgaa aagaggggaa aatattggaa
      421 gatgatgaag tagaaattat aaaaaaatgc tttaaaaaaa gaaaaaaagt gttcccaaaa
      481 gtttgcagac tgggggaaca ctcaataata aagtgctgag aaaactttat ttatagctat
      541 tatatcaaaa aagaaggtga aaaggtgttt tcttctggaa atgttgtagt tgacaaactt
      601 agagaaataa attttgacgg aaatgtaatc cacacacatg gtacgatcaa ttaagaaaaa
      661 aaacgaaaaa aggtgttgag aagccctatt tgaatgcaat agttatctta gcagaaatta
      721 cctattggta tagacctaaa aaaattttta acgatgatgg tcagctactt ggttatcaaa
      781 aaaagtttct tgaagatatt ttgcaaaaat catataagca attaagcaaa aaaacaggat
      841 tatcagaacg agctataaaa gatgcaattg tgtacttaga gaaaaagggg attatcaaaa
      901 gggtttttag aaatatttat tatgagaaaa gagcagttac attatcaaat gttatgtaca
      961 ttgttttaaa tgtacataaa ttgatagaaa ttacttttcc tactttggat tgcgaaaaaa
     1021 aggagtatat gccgaaaatt cgtcagaggg gtatcgaaaa aaagagatat gtctctttaa
     1081 aaaaaggtag aggtatgtac aaatttgtat atacgtatac aaagactact tcacagaaca
     1141 tatcaaagac tactctcgtt atggaagaag aggatattaa tataaagagg atttacagta
     1201 agattagtgt tctttatgac gcaaataacg aagatggtcg aaaattattt caagtgtatc
     1261 actatttgag aaacgctaat gtagatacag aagatatcag aaaaatcatt gaatatttat
     1321 ctgaaaatac tcagtatctt attgctgagt gtattataaa acaacatgaa gcatgctttt
     1381 ttcaaagaaa aactgaagaa gggttatacg attatgtaac atattttttg aatggacttc
     1441 agaaaagata taaaagtcaa tttttagaaa atgtagagcc tatagatcag ttcaaaaaag
     1501 ctttcgaaat caaagagtta cctgaaatta ctatgcataa ttggttgaaa ggagaagaat
     1561 catgattaaa aatcgcttaa tagatcaaat gtggtgtctt gatcaaaata cagatactct
     1621 cgaattaatc gagagtatct gcttcaacac agtagttctc gatttaagag ctgaaaatga
     1681 caattgtgta actcatatca taattaatca aaaaatggct cagcagctct ctgagagcct
     1741 aagaaaatgg gctgaaggag aaaactatga aagcaattaa agaaaaaatc gttagtagaa
     1801 aaataaactg gttagcactc agtgtacttg ttttaatgat tagcgttgtt tttacaagta
     1861 atattgttga agctagcatt ttcaattggt ttgatgacac aaaaagtcaa acagagtttt
     1921 tgaataattc tctttataga ccttacctaa aaaaatacaa tggagatttc cttagtcagt
     1981 tcgggatttg gcttggatgg gctgtggtaa aaggcatgtt tactgtgact gattcgattc
     2041 aaaatatgat tccagatgtg ttggatttgt tcaatttcat tgaaagtaca gggctaaata
     2101 atgtttatca atcagtcata aatacaattg tcgttggatt aatgatcctt tcattgatgt
     2161 ttgttggcta caagatgatt actggaaaag gaacaataga tttaagatct gttggaatga
     2221 atatagtgat gtctgtagcg ttaatt
//
LOCUS       DADQCX010000189         2193 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.197, whole genome shotgun sequence.
ACCESSION   DADQCX010000189 DADQCX010000000
VERSION     DADQCX010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.197"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..469)
                     /locus_tag="J8R83_002805"
     CDS             complement(<1..469)
                     /locus_tag="J8R83_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAZ9575894.1"
                     /translation="MSKRGTIINEWENLTALSNRRLSVQTLTTPLKIQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQ"
     gene            complement(1031..1234)
                     /locus_tag="J8R83_002806"
     CDS             complement(1031..1234)
                     /locus_tag="J8R83_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575895.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(1693..>2193)
                     /locus_tag="J8R83_002807"
     CDS             complement(1693..>2193)
                     /locus_tag="J8R83_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAZ9575896.1"
                     /translation="QYRVVDPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQE
                     TKRKIVPPEIKTWWRLELQLRRGKATDWYAMVHESLDSFASPHFLPTDTKHTDRIMIA
                     GLISDQNLWAGLARHTKYKYRNLLKKESQSDELVNHLRETFSESADVLKKELDTWLLG
                     LDVTEE"
BASE COUNT          630 a          506 c          347 g          710 t
ORIGIN      
        1 attgcgtaat aaaatcatca ggcacatcga taatgtcgca agcaatatca gcacgtgaga
       61 aatgtggttc taaaaataaa tcatggataa agttcttcat cgaacccgcc aaaaattggc
      121 taattttatt tgggttaaag tcaattcgcc cttgcccttc ttgatatttc aaaatttcaa
      181 tgtaagcaat attctcatca tgcttatcca caatttgcca accatttaga ccaacagatt
      241 taacataacc attattttca ttcagtcgca ttaactgttc aaagtctaaa atcaatacat
      301 cattttgcgt gtgataataa atattctctt tgagttttcc aacaatggta attcggtcaa
      361 ttgaccactg tattttaagg ggggtggtca aagtttgcac acttaaccgc ctgttagata
      421 gggctgttaa attttcccac tcatttatga tcgtgccacg tttactcaaa ttttgttcct
      481 cctcaaagaa aaagagactt ttggaaagaa tttccagagt tcacgtaacc ctaaaaattc
      541 atatccaaaa atctctagct tgaagaaacc taaaaatatt cgtataatga acctgagtta
      601 cggagctagg tgaagtagtt tccgtaaata gtcgagagtg ttagcgcact gctcggcttt
      661 tattttgctc ttttttctcg ttttctttga ttatagcact cctcctaaaa aaataaaaag
      721 acctcaggga atttcattcc ccgaacccct tgagcctcct cctgccgaaa tggaaagggc
      781 gcacccgctg tttatttcat tcagctatcg gctttcacaa tctaacacga tcgttccgct
      841 accagtcgcc ttacaggctc cattttcgct cctctaacgt gttttaacga ttgtgccgat
      901 aactaaacga aataaacgct aaaaccgctc agaacgcaaa atatgccatt ttagagctat
      961 tgtagaaaat gtagtttgaa atgcaatttt cttctttcag ctttttattt cccacttgta
     1021 aatctgctaa ttattttcta ccagacaaac cattgatttt ttggctatca gttaactcac
     1081 gattattatg agaaatgctt gtattctttg ttcccttttt gaacgaaata ctaaacccta
     1141 aggtgaaccc ctccttcgcg ctgtcgctaa taaaaagagt gtaaaccttt ctgttactct
     1201 ttgacaaaga gtaacatttt cctaattgtg acatggctgt cacaattcca aacgctctcc
     1261 gagggttttc gctgtcacaa gtgacaacga aaaaaggagc cgaaagcgtg tcacgctctc
     1321 aactcctttt acgctttatt ttgcttcacg caaaataatc gcttatctta aacattgacg
     1381 taaatttact ctcacttatc tgactttttt actcggtatc actccgagta agccgtcata
     1441 ttcattggga taatctcgtc tgcttcgctc taattttcca gagtgagggg taactccttc
     1501 ccccgaatta ccccaaagag tgacactggg atatccctaa atttattata aaaagccaag
     1561 tctctttgcg caactgtttt atccaagtcg gcatttgcgg attcgttagc gttttttcgc
     1621 tcttgctgca aacgcacgac ccaccatgcc gacttgtgct gaaaataaaa aagtggacaa
     1681 aaattcatcc actcattctt ccgtcacgtc caaccccaaa agccacgtat ccaattcttt
     1741 tttcaaaaca tctgccgatt ccgaaaatgt ctctcgtaaa tgattaacta actcatcact
     1801 ttggctttct tttttcaaca aatttcgata tttatatttt gtatgacgag ccaagccagc
     1861 ccataaattt tgatctgaaa tcaatcctgc aatcataatt ctatcagtat gctttgtatc
     1921 agtcggcaaa aaatgaggac ttgcgaaact gtctaaactt tcatgaacca tcgcatacca
     1981 atcagtagct tttccacgcc gtaactgcaa ttccagtcgc caccaagttt ttatttccgg
     2041 tggtacaatt ttccgtttgg tttcttgttc caattttttg ttgtacatcc ttatttgtcg
     2101 ctcactggca cgactacccc aatatgccgt ttccagcttc ccagaccgcc catagattgg
     2161 tttgaatgaa acagggtcaa ccacacgata ttg
//
LOCUS       DADQCX010000190         2173 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.198, whole genome shotgun sequence.
ACCESSION   DADQCX010000190 DADQCX010000000
VERSION     DADQCX010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.198"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..424)
                     /locus_tag="J8R83_002808"
     CDS             complement(<1..424)
                     /locus_tag="J8R83_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAZ9575897.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
     gene            complement(533..1564)
                     /locus_tag="J8R83_002809"
     CDS             complement(533..1564)
                     /locus_tag="J8R83_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9575898.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          686 a          345 c          365 g          777 t
ORIGIN      
        1 gaatctgttt tgattttgtt ccatttgaaa tttctctcac tcgctttttt gtctcatcat
       61 caaataaaat gaaagggtct tctaaacgat cgataaatac ttccattgtt gttgttggta
      121 gatgataaga agtcatgaca ggcactgcac caaggtaaga cacagaaaca gctagaaggt
      181 atgtgtcaaa agcggaactc ttataaataa taactttgtc tccggatttc actccaagat
      241 gagccaattg ataagcccgt ttcaacacac tttcgcagca ttttttgtaa gttgtttcaa
      301 gtcctaattc tgggaaagct gaaagtggct catcaaagat aatcggggtc tcggaaaagt
      361 tagctgcagc ttcttgaaaa ttcgtaaata agttcaaagg ggaatacgtt atggtctcca
      421 tcattcacac tccattatct tttgttaagt aatatacaaa ttcaagataa tcgtaacata
      481 atcctttata taataacata gtttattgtg aaaaaaagat catacatttg ttttatatgg
      541 aagaaacccg aacgaatgcc gctaattcgt gataagaaaa atcaaccatc ttttcccaga
      601 tatcttgaaa agaatgggat gagaggtatc gattaccaca taaataattt accgcgtcag
      661 catcatctaa atatagttct gcataataac gatatgtttt tctgcatagt tctggcgata
      721 cgtttttata tactgtaatt ttgctcaaaa tttggcgaat agtccgagga gaaatttgct
      781 gatcatgtga ggaacgaaaa acaaaagaat tttcgtccgt attttgtgct gttaacttaa
      841 aatagttctc cagaaatggc atcgcttctt ttggtattgg tactttattc agtctgtttt
      901 cttttctatt cagattaaga atctgcttgg tcaaagatac atctttacgt ttaagttcta
      961 ctacttcatg gatctttaat ccgcaataca gaagaatggc agtaattgca aggttcctcg
     1021 gtctattctt ttcttcaaag ctagcttctc tgcttgtttg aaagccttca atcgggataa
     1081 acaaatgctc aaaatctttg aaaagttctg catcgatata tcgcggagct gctttggttg
     1141 tttccggtaa acttgtaccc aaaagagaaa tctcttcttc aatcagtcct ttttgataca
     1201 aaaatcgtaa aaaatgattt aatgaatatt gcttccttga aatcccgtaa tagctatttt
     1261 caaacaattg ctccgtttct tggttcgctg tagtttggaa cgaacgagta tgtcgataga
     1321 ttttagctaa gaaattctga taatcttgtt tttctaaatg gataatcagc tgatcatcca
     1381 cttcttcaga aaatactttt ctcaaataat cagtaaacag atgaaaatct tttgcgtatt
     1441 catagcgact gcctaatgaa agggaagaac gattttcttc taaaaactgt tgaaagacgg
     1501 aagggagcaa gtgtgtacgt tgctttaact tttcttgcag ttgttttcta gttttgctgt
     1561 ccattacaaa ttccctccaa tagtgttcat tttctatatt ttaccgcatt tcatcaaatg
     1621 aagatagaca gtttgtcttg atcttaggaa gcaaattttt aactaagtac tagctaaaag
     1681 atatgaagta agaagataca tttttagtta ttttattagt gcagtcattc ttttgatctt
     1741 ttaattgatt tatcctcttt ttagctatgt ggttacttca tgagcaatga aatggatttg
     1801 gttcgttcta atggcaggag gctctttctt ttatttccga aaaattagaa aacatttttt
     1861 cagaatcgat tggctctcca tttattcaat aatggtttgt ctaacgatat tgttgggata
     1921 attcttaaag aagtattaga aatagttggt acttcattac tttacatgaa gatttattct
     1981 atggtaggag caattatatt gagaattaat ccttttttat ataagttgtt tgcttattga
     2041 tggattggat aaattaaacc atcacaacga gtggaaatta tatgaaattt ttcataaaaa
     2101 ttcatataga aacaaatgac attttattag aatatgactt tcattaacat aaatgttttc
     2161 aaatttcaat taa
//
LOCUS       DADQCX010000191         2071 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.199, whole genome shotgun sequence.
ACCESSION   DADQCX010000191 DADQCX010000000
VERSION     DADQCX010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.199"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>2071
                     /gene="acm"
                     /locus_tag="J8R83_002810"
     CDS             <1..>2071
                     /gene="acm"
                     /locus_tag="J8R83_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAZ9575899.1"
                     /translation="ITSLIPVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSFD
                     EKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNENI
                     KNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYYK
                     TGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQKV
                     YRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQINF
                     ENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPNV
                     TFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSNE
                     LKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPVP
                     DAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVVT
                     NENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTNL
                     PKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEKT
                     EREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSFA
                     VIIGLLIV"
BASE COUNT          812 a          341 c          406 g          512 t
ORIGIN      
        1 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
       61 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
      121 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
      181 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
      241 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
      301 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
      361 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
      421 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
      481 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
      541 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
      601 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
      661 aggagaagag ggaatccaac aatttttaca agatttcccc agcgctacat ttaatttttc
      721 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
      781 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
      841 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
      901 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
      961 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
     1021 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
     1081 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
     1141 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
     1201 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
     1261 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
     1321 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
     1381 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
     1441 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
     1501 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
     1561 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
     1621 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
     1681 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
     1741 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
     1801 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
     1861 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
     1921 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
     1981 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
     2041 ttttgctgta atcattggtt tattgatagt a
//
LOCUS       DADQCX010000192         2063 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.200, whole genome shotgun sequence.
ACCESSION   DADQCX010000192 DADQCX010000000
VERSION     DADQCX010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.200"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..914)
                     /locus_tag="J8R83_002811"
     CDS             complement(<1..914)
                     /locus_tag="J8R83_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAZ9575900.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="J8R83_002812"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="J8R83_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAZ9575901.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT          688 a          370 c          402 g          603 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agc
//
LOCUS       DADQCX010000193         2034 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.201, whole genome shotgun sequence.
ACCESSION   DADQCX010000193 DADQCX010000000
VERSION     DADQCX010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.201"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(274..>2034)
                     /locus_tag="J8R83_002813"
     CDS             complement(274..>2034)
                     /locus_tag="J8R83_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAZ9575902.1"
                     /translation="FLKGTQAYFRDVLLMHGFILFICLPLLSSTTRFILHRGAIDYLS
                     YDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKKKEPISLKQLLHLT
                     ILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIMDFIFANRWIIVSS
                     FLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLLAITGQFIVIGGTI
                     LLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNIVMSTVGIFYIIVD
                     FMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCLYNMDYLTSAVQTK
                     PVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGHFVVMHDANLRHLT
                     GVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKLLIEIKTSKKDSDD
                     LVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILPFNIVGPPVTPADF
                     LTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGIITDEMGLLNESVK
                     QTDEEITYSDKLLNFVLGVG"
BASE COUNT          711 a          372 c          379 g          572 t
ORIGIN      
        1 tatttttgag aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga
       61 agatatgcca aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc
      121 aattcctgct attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca
      181 cattatgagc gtcaaacaaa aaacgcatat acctgcggtg gcaggttatg cgttttttgt
      241 tgtataaaga cttttttcat taacgatttt tgattagccg actcccaaaa caaaatttag
      301 cagtttatct gaataagtga tttcttcatc tgtttgtttc acactttcat ttagtagtcc
      361 catctcatcg gttatgatac catccacacc ataaaacatc atgcgactca tagcatctga
      421 atcgttgatt gtccatacat atacttcttt tccgtcttgg tgggcagaat taatgaagtt
      481 acggttgatc gtactatatt ccattgtcag aaaatcagca ggcgtcacag ggggcccaac
      541 aatattgaaa ggtaagatgt agcccacata aaagtttggt tctgcttctt ttaaatctga
      601 aacggtttgg tacgtcaaac tttgcaaaat atgatggttc tctaagataa ctttgcggta
      661 tttatggaca aatcgttcga caaggtcatc cgaatctttt ttagaggtct tgatctcaat
      721 aagtaatttt tggtttagct tatgtgcttt ttccaaataa gaatcaaaag aacaaacagg
      781 ggcttgcact ccgttttcag taactgtaag atttgtcaat tctttcaatg taagatcctg
      841 tggtgttcca tttacccctg ttaagtgacg aagatttgca tcatgcatca ctacgaaatg
      901 accatctttt gtttcctgaa catccatctc tacataatca ggatgatagt ctctgcttgt
      961 tttttcaagt gcttctaaag tattttgcgc cccattttgg gtactcacac ctctgtgaga
     1021 gacagtcact ggttttgtct gaacagctga agtcagataa tccatattgt aaagacagac
     1081 gccaataccg aaaaaaactg caaaaagagt caaaccagtg tttttcagcg cagagaaacg
     1141 caagttgggg gcttgtggga taaaccactt agggatctca ggcaagaagc cttcgtcatc
     1201 catgaaatca acaatgatat aaaaaatccc tacggtagac atcacgatat tgaataataa
     1261 aatcccttgt aaaagcgtca tagcaaacac agcgctgatc aatgcatagt ctgggaaaaa
     1321 ttgttcaacc atactttgtg ccaaaataac aacgatatat cctaaagaag aaaggagtaa
     1381 aatcgtaccg ccaatcacaa taaattggcc cgtgatggcc aaaagacgcg atttggtcaa
     1441 tgaccagctt tcccgaatgg ctgctcgaaa aggacgatcc cgtagaatca tttccggtaa
     1501 agcaaaaatc agtcgaatcc caatatagcc aaggaaaata taaacgagta aaaaggaact
     1561 gacgatgatc caacgattag caaaaataaa atccataatg aaagcgggga tttttatttt
     1621 tgacagtaga tcagaattaa aacttaatcc gctgatcggt agaatcaata aaaaataagc
     1681 aaggaaaaac aaaaaagtaa tgggtctcac tttcttcagc tgaagtatcg tcaagtgtaa
     1741 gagttgcttc aaagagattg gttctttctt tttaataaaa aaaacactca tcaaaagaaa
     1801 agtaaattcg aaataaacta acagtaaaat cgtcatcaaa actacgatta acgagagtag
     1861 aaccccagga tgttgagaaa aaattgaagg aatattgtca taagacaaat agtcaattgc
     1921 ccctcggtgt aaaataaaac gggtcgtact gctcaataag ggtaaacaaa taaataaaat
     1981 aaagccatgc atcagcaaga catcacggaa ataagcttgt gttcctttta aaaa
//
LOCUS       DADQCX010000194         1842 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.202, whole genome shotgun sequence.
ACCESSION   DADQCX010000194 DADQCX010000000
VERSION     DADQCX010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.202"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            161..358
                     /locus_tag="J8R83_002814"
     CDS             161..358
                     /locus_tag="J8R83_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575903.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            464..946
                     /locus_tag="J8R83_002815"
     CDS             464..946
                     /locus_tag="J8R83_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575904.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1004..1600)
                     /locus_tag="J8R83_002816"
     CDS             complement(1004..1600)
                     /locus_tag="J8R83_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAZ9575905.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT          574 a          279 c          366 g          623 t
ORIGIN      
        1 ttctaaatac aacagctgtt ttaattgtga aaacgaaaac agtacgctat aatgcctgta
       61 aggttgattt ttaactgtaa ataaaaatca atgagttaaa tctccaaaga aatagcagtg
      121 gtaatgtgga gaaaagttcc agcagtttag gaggattttg atgacggaag aaatgattaa
      181 tttaggagaa caatatgcat gcaaaccaat tggttttaca aaaacggtca ttggtgaagt
      241 tgtatcaaaa atgacaaact gcgccgtggt caaagttgcc caatgtgctg cagaggacca
      301 agaattatta gatgaaaaag caagcatggt tgttgcaaaa tatgatacat ttgaataaag
      361 aaaacaattg gacgtgcggc gtgctgcaag tccaatttct ttgagaaggt aaatcagtat
      421 tcttttccta ttttctggag aagaaaaagc gaggcgagtt gtcatggtaa cattctttac
      481 ggttctattg tttttattcg ttgttgtgat gtttttattt ctttggctgg ttcgaaaaga
      541 aattatttat cggactgtgc gaaatcgatg ggtctacttg gtgataccct tcttagtgtc
      601 actagtcatt tggtatacac tcatcagtca tcctacagca gatgaattgg caaaagggat
      661 cttgtcagca atgattttta ttagtttttt gttggacagt agaggaatca cagaagaagg
      721 acttgttttg aatagctttg acaaaaaagg tgttcctttt tctgagatca ataaaattgt
      781 attatatcag ccaaaaggtt ctaaaatcgt aaaaatgaat tttttccgaa acggatggcg
      841 aggaccgatg ctgaaatttt ctgcatcatt agaagaatta gttccatttt tgtcccaacg
      901 cttaaacgat gaggcagaga ttgatattat gattgatcca gaataaaaac agaggttgcg
      961 acaagatgtt tgtcacaacc tctgtttttt atttcaaata aaattatcca aatacgcgga
     1021 agcgatcggc atcgttcatg tattcttttt ccccagccgg tgtttctggt gaaccgaata
     1081 ctaattgcga acgtagtttc cagtttgaag ggatattcca ttcttttgca actgcttcgt
     1141 caataactgg gttgtaatgt tgcaagtttg cgcccaatcc tttatcaact aatgctaccc
     1201 aagtattagc tgttgcgatt ccgtttgatt gttctgacca atctgggaag ttgtctgcat
     1261 ataattcaaa ttgttcttgt agacctttta ccacgtcagt atctttgaag aataatactg
     1321 taccataacc atttttgaaa ccagctaatt tgttttgtgt atttgggaaa gcttctgctg
     1381 gagtcaatgg gcgaagtgct tcttcagtga tttcccaaag tttttcatgt gcatctccga
     1441 aaaggataac tgcgcgtgtt gattgagcat tgaaagcagt tgggctttct ttaattgctt
     1501 ctttgatcaa agttgttaat tcttcattag aaagtgaaac attacgtcct agatgataga
     1561 ttgaacggcg gtttttcaaa gtgtcagtaa aagttgtcat aataaaattt ctcctttgat
     1621 ttgcgttttg cattttttta attgattacg aaatgaagta tagcacctta caaaaagtaa
     1681 gtaaacagat atgctcacaa aaaataagcg aagttcaaaa aacaatttta ataagaaaaa
     1741 tcgttatgta aggattttct tagttatcgc tttcattgtt gtgttttagg aatttttgct
     1801 tatttgaaaa aaacagctga tatataatta ttaaatctct at
//
LOCUS       DADQCX010000195         1818 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.203, whole genome shotgun sequence.
ACCESSION   DADQCX010000195 DADQCX010000000
VERSION     DADQCX010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.203"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(358..855)
                     /locus_tag="J8R83_002817"
     CDS             complement(358..855)
                     /locus_tag="J8R83_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9575906.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(895..1704)
                     /locus_tag="J8R83_002818"
     CDS             complement(895..1704)
                     /locus_tag="J8R83_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9575907.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
BASE COUNT          525 a          338 c          312 g          643 t
ORIGIN      
        1 atcaagtaat aagaacagcc aagtaaaaac agcttcttat gtttttactt ggctgttctt
       61 attactgcag atgcaagctt ttgaataccg tttaaggaag aggttgtgaa atcagcgttt
      121 tgacctgagt attagcttaa caaacggaaa aatagttcct catattttgc cgtttgttaa
      181 gctaataccg agggtcagct gattgaacac catttaagaa agaggtcgtg agcctgccgt
      241 ttcactctgt gtcataaaaa agccaatcta ctttgataga aaaagcacgt aggactaaaa
      301 cagttctgcg tgcttttttt attgtgtgtt aaatatcgta aatgaagata gatattttta
      361 tgattcgacg atagagacgt tgaaatcttt caacagctct aaagcggatt ctccgtgttt
      421 tctactggag actaacattg gatcaacaaa aaagtctgct tcaggaaaag cactctgcag
      481 gcctatcaga ttagagagta cacacaagtt tgtttcaatc ccgactactt cgatctcttt
      541 ttgttcttct ttgctttcaa ataaagtttc ctggatttca gctaaagttt caggtggaat
      601 cgtaaagtaa tactttttaa tcactcgttc attttcttgt ggagaaagaa gagggatcaa
      661 ttgcaaatct tctcgttctt cttctttgtc cttcagttca actggtatat cccgtgtgaa
      721 gagaatatat tcattatttt ggcgtgcttt agctaatctt tgagcaatac gttctgccaa
      781 ttgatctgac tctggaatat aaaattcgct gtttggatca agaatatgat tttgcatatc
      841 aataataact aacattttct ttcctcctac attcatatcg tcattttatt ctttttaata
      901 gaagtttttt aaaatataag caacaccagc ttcttcattc gtcagtgtta cttggtttgc
      961 aatttctttt acttgtcgct gtgcattccc catcgcaata ctcaacccgc tgtaattcaa
     1021 catagcaatg tcgttttctt gatcgccaaa agccatgatg tcactcgatt cgattccaag
     1081 gtaatccgcc agaaaaacaa gtgaatgagc tttagtgata cctgtaggcg tgatttctaa
     1141 gaaatgcgga tcagagaata ctgattggat accatctgct tgcagatctc tttgtagctt
     1201 ctgtagtttt tcttcactct tatctgttaa tgctaattta agatagctaa gagaaggatc
     1261 ttccaacata tttaaaattt gatcaaaaga atggttctgt aaattgaaat gttcataata
     1321 agggtcatct ttgactagat ttgattcatc gaatgtcagc tgatcatctt gggtttctcg
     1381 gctagcaatg atggatattt tcgcttcttg agcatagaag aaggcttttc tcagtgtatc
     1441 gctatctatt tttgaacgtc tgagaacttt cgccattttt ccatccttca tttcagcaat
     1501 cagtgaacca ttggaagaaa tcaaatagcc accgattcct aattcggaaa aaatatcttt
     1561 agcagaaatg ctgttccttc cggtagcgac ggttacgatt ccgccatttt catcaaattt
     1621 ccgaagtgct tggatatttt cttctggtat ctttccattt cgatcaagca aggtaccgtc
     1681 taaatcaatc gctgctagtt tcattttatc ttcctacttt ctttttacat atctattttc
     1741 ctgttacctt aagattaaat gagaatttaa aaaaatgaaa ctaacttgct ttgtcattat
     1801 gaattttttc aaaaaaca
//
LOCUS       DADQCX010000196         1723 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.204, whole genome shotgun sequence.
ACCESSION   DADQCX010000196 DADQCX010000000
VERSION     DADQCX010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.204"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(32..580)
                     /locus_tag="J8R83_002819"
     CDS             complement(32..580)
                     /locus_tag="J8R83_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575908.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(581..1438)
                     /locus_tag="J8R83_002820"
     CDS             complement(581..1438)
                     /locus_tag="J8R83_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9575909.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
BASE COUNT          485 a          347 c          247 g          644 t
ORIGIN      
        1 taaaggtagt tacttagttc ttctttgatt attatctaac tttattattc attccccacc
       61 ctttgcgcag tgagtcttcg gtatcttgtt ttatctgact ggtagttctt attatttctc
      121 cacgatcatc taattctgga acaattggat atttttctct gaacaagtct agttctttca
      181 ccacgtcatt aaacaaatct tgcttatctt cttgcgtaag attctgttta atatactcat
      241 ctaaagcttt tctaagcaat tcatctcttg tcatattagt ctcatacttt tctactaaaa
      301 ctctggaagt cgcatttaac aaagtcgaca gttttaaagg atgcttggtg gaataaacct
      361 tatcaaactt tctgattggt gcgccaactt tttttgttct tcctctactc tgtctttcaa
      421 cattggagga agtttttatt tcttgaactt ggtgcacttc taattgctta ttttcagatg
      481 gtgtaattgc ttgctgcttt ttctttgctt ctgcttcttt ttttattttg gcgagtcctt
      541 tattgttccc aaaaatatca agtcctttga tgtcagccaa ttactccacc tccgcatacc
      601 aattctcgtg ttcttccaat tctttcaaaa tactgataaa taattcgtgg cttttgcgat
      661 cccattgttt taagagacct ttctttgtct tctccatcgt aatacctgat ccgtcgtatc
      721 gttttaagcg cgcatttttg agtacaacat ttttaatcaa atgttcccca taaatctctt
      781 gggcttgttt atacatttcc tgatctactg cgtcaccgct ttccaacatg aaaggaataa
      841 caccagcaac atataaattt gtatcaaatt ctttcacaaa aaagtccata tactcaagat
      901 attgcatcgc atttctcatc gattttactt gggtctgtaa gacgacgatt gcccagtccg
      961 caatgtacat cgcggattta ctatatacag aaatagaagg tgggacatct aaatagatga
     1021 cgtcaaactc atcaaataat ggttctagct tttctttcat atatttgaat tgggataatg
     1081 aatcattata ttggtctttg atccaatcat catacatttc aaaggacatg tctgctggaa
     1141 gtatatagag gttattgatt actttataga cagcctcttt aggtggaaga ttgtttatca
     1201 acacgtcagt cacagtattt tcgtaaacaa tcggttcacc ttctccgcct ccttcttcgt
     1261 tagtgaagtt catatgcgtt aagttcatca catcagaagt atttccttgc atatccaagt
     1321 caattatcaa ggttcttttt ccttcattaa ctgctgattc aaaccctaac atttgcgcgc
     1381 acgtactttt acctacgcca cctttaaaat taccgattac atatttcttc gctaccacgt
     1441 tcctacctct tttcttttag caatattcat ttgatactat tataacatat ttatttttag
     1501 ttactaccaa aaaaaagata tatatgtact accttataat taataaggaa aaggtagtac
     1561 ataaataagg aaaagctgaa atatattgat ttatagcttt cctcaaagta atgacgttat
     1621 ttaatttatc gagaagcaga gaatactcgc gactttagtc atgtagacga atcagatttt
     1681 cgataaaaaa gaagccgtcc ttcttaagaa cgacaacaaa tca
//
LOCUS       DADQCX010000197         1719 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.205, whole genome shotgun sequence.
ACCESSION   DADQCX010000197 DADQCX010000000
VERSION     DADQCX010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.205"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            387..575
                     /locus_tag="J8R83_002821"
     CDS             387..575
                     /locus_tag="J8R83_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAZ9575910.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            653..1666
                     /locus_tag="J8R83_002822"
     CDS             653..1666
                     /locus_tag="J8R83_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9575911.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
BASE COUNT          576 a          277 c          361 g          505 t
ORIGIN      
        1 ttttagttag tctacattat tttggcgatt tgccaataag gactgttgag ttgtgcaaaa
       61 tcaaatctgg gtcagaatga acgtcattct gtctcagatt tttcgttatt tcaatttgat
      121 taactgattg atcaaaaaga tttttatttt catattctca aatgattcaa cactaaatat
      181 acatgtttga cgcggaaatt attattcgat tttggcggca tcagggggga tgacgacgta
      241 gcagacccat tattttactc aagaaaatgt ccgtgcctat tatttagaat acgatagtga
      301 acgtgctggg agttttgttc ttttagagaa agtctctgaa gataaattag ttgtcttaga
      361 ttttgactgt aacgaaaaat ggcgaaatgg aagagcacca gcaagtgatt gaccggatct
      421 acgaagcgac acgatatctg cctttggatc gtttgtgctt aagtcctcaa tgtggatttg
      481 cttcaacaga agaagaaaat gttttgtttg aagaacaatg gaaaaaattt cttttgtcaa
      541 aagcattgca gaagaagttt ggggaaaatc attaaatcat ctaggagagc ttgataggaa
      601 ataacactat ggtataatca gaatgcttaa tactaactac tgagggagcc ttatgaaaaa
      661 gaaaattctt aaatttatcg gatggttctt cggaatcatt cttgggatcg cgtttgcaat
      721 ctttcttgcc ttccagcttt cccccagacc tggagcattc ttgatcaacc atatgttttc
      781 aaatactgtt caaatcactg ataaaaaaac gttcgatcaa gcagaaaaaa acgtggcgaa
      841 aaaaacagat ttgacgtatg agtccaagta taaagagaat acttatgaca tctactatcc
      901 aaaaaacagc aaggggcctg ttcctgttct attttgggta catggtggag gattcgtcgg
      961 cggagataaa tcgggtgtca aagaatttgc gacaaaatta gtttcagacg ccaacatcgc
     1021 agtggttgcg atgaattatg aattagcgcc tgattcagaa taccctaatc aagttcttca
     1081 agtgaatgaa ctgatcaaag atttattagc tgaagaaaaa gacgacaaat tgctagacat
     1141 ggaacaatta ttttttggtg gagatagtgc aggttcacaa atcgcattgc aatatgcagc
     1201 tatacaaacg aatgatgcgt atgctaaaca aatgaaaatc aaacagctac ttccaaaaga
     1261 tagtctgaaa ggaaccattt cttattgcgg acctgttgat ttgaagctaa cagcacagca
     1321 gcattcggat gatcgattta tgaagttttt cgtcaaaacc gttgcgtggt cgttgattgg
     1381 aacaaaagat tggaaaacga gtgagcaatt gaaagaagct agtgtggctg accatgtttc
     1441 taaggaattt ccgccaacgt atataactga cggaaatgca tactcattcc aggagcaagg
     1501 tcaagcatta gaaaatcggt tgacagaatt aaaggtaccc gtgcaatcct tgttttatac
     1561 agatacaaaa aaagagatta cccatgaata ccaatttgat tacacgctaa aagaatcgca
     1621 aaattgttac cagcagacat tggattttgt gaataagtat aagtaagagg ttgtgaaaaa
     1681 gccgtttcgt tttgagtatg aagaaacgaa gcggctttt
//
LOCUS       DADQCX010000198         1614 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.206, whole genome shotgun sequence.
ACCESSION   DADQCX010000198 DADQCX010000000
VERSION     DADQCX010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.206"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1330
                     /locus_tag="J8R83_002823"
     CDS             <1..1330
                     /locus_tag="J8R83_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9575912.1"
                     /translation="IIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECGTSLFI
                     KGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQEYDKV
                     ILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYIGVEIA
                     EAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYLGRKKI
                     EKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKDIYAIG
                     DCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFNYNFYA
                     AGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQLCSQED
                     LSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            1442..>1614
                     /locus_tag="J8R83_002824"
     CDS             1442..>1614
                     /locus_tag="J8R83_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9575913.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSEL"
BASE COUNT          637 a          204 c          266 g          507 t
ORIGIN      
        1 aattattggt tcaaaccatt cagggctagc cgcagctcga tttctaaact taagcgattc
       61 aaattatgaa gttattctaa tcgataaaaa atcagaaatt agttacttgg aatgtgggac
      121 atcgttattt ataaaaggag aagtaagtaa tttagaagat cttttttatc aaaatagaat
      181 gacactaaat tctgagataa aaaagttatt tctagagaca gaagttgaca aaattgatat
      241 tcaaaataaa aagattagtt gtgtaaaaaa agatggtaca agattctctc aagaatatga
      301 caaagttata ttagctacag gttcaaagca aattatgcta gatataccgg ggaataattt
      361 agctaatatt ttttcgataa agaattttcc aaatgcaaaa gagattttta aagctttgga
      421 tgatagtact attaaaaaag taggaattat tggagcagga tatattggag ttgaaattgc
      481 tgaagccata agaaaaagag ggaaagaagt atatcttttc gatgttgcag atagagtgtt
      541 gtcgacttat tacgaccgta gtttttcaga taaagttgaa gaaatactat caaaaaatgg
      601 aatacatctt tgtctatcag aaagtcctaa aaaatattta ggaagaaaaa agattgaaaa
      661 aatagtcact acaagtggta cccaatactc tatggatatg gtcgtacaag ctataggatt
      721 tctatctaat agtccaattg gggaaaagga actcttgaga gatgttagtg gagcatatct
      781 aactaatgaa taccagcaaa caaatataaa agatatatat gctattgggg attgtgctac
      841 aacttttttt acgtccatta atagaagtag tgttgatttt tctatttcta atgctctaag
      901 aacagcttat attgcaactc aacatattaa caatcaagat tttacacctt ctggttccca
      961 atttacaaat ggcttttcta tatttaatta caatttttac gcagcaggtt tgaatttaaa
     1021 aacagcacga ttattaagtg agtctataga ttatatagaa atagaagatt tcattagacc
     1081 tgcttttttg agaaaaaata gtcgtgtaaa attaagaatt agctttgaaa aaaatacaaa
     1141 gagaatagta ggtgtacaac tttgtagtca agaagattta tctggactat tatcaatgtt
     1201 ttctcttgct atagaagaac aaattacatt agacaaattg aaaatgttag attatttatt
     1261 tcatcctagt tttagccaac cctataattt tattttaaag gcagtaacag gattaaacat
     1321 tgaaacataa tcgttactaa atgaaatcaa gaaatatact gtattactca attcattgaa
     1381 aatatttatc ataattttta atagaaaaca ctattaaaga gaaaaaagag aggtaaatca
     1441 aatgaaaaaa tctttaaaac ttgcatcagc agttatatta atgtcccaac tccttatagc
     1501 aacacctttc catgtgttgg caagcgaaaa ttcaacatac aaaattgcaa aagaaagaac
     1561 cgagacgact gaaatgagta attccgatgt aacagcagag agtagtgaac tttt
//
LOCUS       DADQCX010000199         1606 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.207, whole genome shotgun sequence.
ACCESSION   DADQCX010000199 DADQCX010000000
VERSION     DADQCX010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.207"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            40..438
                     /locus_tag="J8R83_002825"
     CDS             40..438
                     /locus_tag="J8R83_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAZ9575914.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            422..1117
                     /locus_tag="J8R83_002826"
     CDS             422..1117
                     /locus_tag="J8R83_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAZ9575915.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          611 a          228 c          317 g          450 t
ORIGIN      
        1 aactattaga caaatgatat tttacgagga ggaacagaga tgacgatctt tgaaacggtt
       61 gtaacagatg ttggtataga agcagaagta ttcaggaaag aaaaaataat gattttattt
      121 ggagatgaag caccggaaac attaacagat tattgttata agattgaatt gaatcaggta
      181 agaaaagaaa taacttgtga tatgaagctc tgttttgata aacaaatgta tgtaatcaca
      241 gcagtaggag atgttgtcca aactaatttg aatgaattag gacatatcac gataaaattt
      301 gatggatctc atgagccgga acttccagga acaatgtatg tagaagataa ggaaatgccg
      361 catttaagaa aggggacaat cattaaaatc gatcaagagg atcagaatgg gggaaagcta
      421 tatggaaatc atgcttgata cagcaaatac aaaaagtatt tattcttgtc aacagttttt
      481 gaatttaaca ggcgtaacaa caaatcctac aattctgaaa aaagaaggag cgtcaaactt
      541 cttctcgcat atgaaagaaa tcaaaaaaat aatcggacag attcctatcc atattcagac
      601 aataggaaga acggaagaag aaatgataga ggatgctcga gttatcatag aagaactggg
      661 aaaagatacg tttatcaagg tgccggtgaa tcaagcaggc cttcaagcga tcaaaaagtt
      721 gaaaaaagaa ggttatttga ttaccggtac agctatttac acagaattac aagggtattt
      781 agctattaat aatggagcag attatattgc accttattat aacaggatgc aaaatcaagg
      841 cattgatgct atgaaagtga ttgattcgtt gcggactgag atcgaacgta cgcaaagacc
      901 aacaaaaata ttagcagcta gtttcaaaaa ttgtgaacaa gtcactacag ccattcgatc
      961 tggagctcat gcgataacgt taggtaaaga gctactagat caagtattag agatgccctc
     1021 gattgataaa gcagtgaggg gcttccaaga agattgggtg caaactttcc aagcagaaac
     1081 gattggtgaa ctaaaaaagg tcgctgatta cttctgaatc aatttctcca taaaataaac
     1141 gatagccttc tcgaaaactc gaggaggcta tctgacgatt caatattcat taatttaaag
     1201 tttgggtgac tattactaac tattacttat ttctcattta aacgatgtat tccctaacct
     1261 ctaatacatc cttgtaactc tgaagttacg ccagttttga ataaatttca taaaaacaaa
     1321 tgaaaagtgt cgcataaaaa tatctttcgt gtttctctag tataacagaa taagaagaac
     1381 aagtccagaa gggatatttt tagtcttttt taaaataact tttcagtcga gtttgagttt
     1441 atgatagttg tttttgaagc gatacggcaa gtgaaaaaat agggaagcat gaaagaatct
     1501 acttaatggc gcattgattc atgtgataga aataaaaaac ttttttaaat tatatcctca
     1561 tgattgtaac aaatccagtg atttgttttg gtacaaataa aaaaag
//
LOCUS       DADQCX010000200         1568 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.208, whole genome shotgun sequence.
ACCESSION   DADQCX010000200 DADQCX010000000
VERSION     DADQCX010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.208"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            322..1452
                     /locus_tag="J8R83_002827"
     CDS             322..1452
                     /locus_tag="J8R83_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAZ9575916.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
BASE COUNT          442 a          257 c          340 g          529 t
ORIGIN      
        1 tatagtaata accttgttag gtgaggctcc tatacaaaca taggctgttg cccagaaacg
       61 tcgaaagtcg ccaatgggta aaacagaaac tgttggatta aggctttttc caatagctaa
      121 gaatgttttc tttacgttgt atagtgctaa aactcggacg atgagatgat gctaggtcag
      181 aattcttgtt cgaaaaggtt tctgaccttt tctttatatt tttgtgactg acttatttga
      241 tgagacaaac tcgctcctca cctgacaagt ggattgctgt gtgaggagga gatgcggtga
      301 aaaaagatcg attggtggat tttgggtcct tatttgactt tgtccatgat cggtctttta
      361 gaagtataca gtgccagttc ttatcgttta ttgcaagccg atgaaaatac aaaaagtcta
      421 ttattgcgtc aactaatttt catatttttg agttggagcg tgatcttctt agctcgttca
      481 gtcaaactac actatttact tcaccctaaa atagcaggat acggtttagc cttatcgatt
      541 ttctttttag tattagtaag aatagggata ttcggtgtca ctgtcaacgg cgcacaacgt
      601 tggatctctc tgtttggcat tcaattccag ccttctgaac tggcaaatct ttttttgatt
      661 ttttatttaa gctggttttt tcgtgacgga aatagtagcc caaaagatct aaaaaaacca
      721 ttcctgatta cagtaggtat aacttttctg attttatttc agccaaagat tgctggagca
      781 ttgatgatcc tttcgattgc gtgggtcata ttttgggcag cggcggttcc atttaaaaaa
      841 gggatctatc taatcgttac tttttctgca ttgctgattg gagcagcagg cggggtatta
      901 tatttaggaa ataaaggttg gcttccacag atgtttaatc atgcttatga aaggatcgcg
      961 actttaagag attcttttat cgatagtcat ggtgcgggct atcaaatgac ccattcgttt
     1021 tatgcactat ataatggtgg catatttggg cggggattag gaaatagtat cacaaaaaaa
     1081 gggtatcttc cagagacaga aacagatttt attttttcga ttattacaga agagcttggg
     1141 ctaatcggtg cattgtgtgt gcttttctta ttgttctcat tatgcatgag aatcttttgt
     1201 ttaagcagtc gctgtaaaaa tcagcaagct ggattgtttc ttttaggatt cggaactttg
     1261 ctattcgttc agacgataat gaacgtggga agtatcgcgg ggctgatgcc aatgactggt
     1321 gtgccattgc catttgttag ctacggagga acaagttatc tgatcctttc tttaggaatc
     1381 ggaatcacgt tgaatatttc ttcaaagata caggccgaag agttggcgct ctatcgacct
     1441 gaaaaacaat aaagagaaac tgagaaactc tcagtttgaa ttatcataaa gtacaatctt
     1501 ttatttttca agcgagaggt tcttttagaa agaggaattc gcaatgaaag tatctcaaaa
     1561 aatcatat
//
LOCUS       DADQCX010000201         1549 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.209, whole genome shotgun sequence.
ACCESSION   DADQCX010000201 DADQCX010000000
VERSION     DADQCX010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.209"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(145..459)
                     /locus_tag="J8R83_002828"
     CDS             complement(145..459)
                     /locus_tag="J8R83_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575917.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            745..984
                     /locus_tag="J8R83_002829"
     CDS             745..984
                     /locus_tag="J8R83_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575918.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1346..>1549)
                     /locus_tag="J8R83_002830"
     CDS             complement(1346..>1549)
                     /locus_tag="J8R83_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575919.1"
                     /translation="KQKVIGEVISKLENCVVICVDEYHDVDRNEILEKCGKVVAKYTH
                     VYELETTEYLYNYSNKYEHTLVS"
BASE COUNT          537 a          273 c          211 g          528 t
ORIGIN      
        1 tataaactct agagaaatta attcatccta acataaaata attgttcact caaaagtttt
       61 tctagaacaa ttaaaacagc aggcttcaca ttcgctatac atttgtaaga agtaataatt
      121 cctgtactaa aaggcataat tgctttaatt attttttgac ttctcttcaa acacaagaag
      181 tagttgtgta ataattgcag aaataaggat tccaataata gatataaaat ttgacatgga
      241 aacgtctata acattaaaag aataaagtgt tgaagaaagt aaactgattg aaataacccc
      301 tccgtaaaaa atagtctgtg aatataccca ctttttttca gaagacgtac ttcgtttggt
      361 tctaaaacct atccctgcat ttctactctt atcaaaaaac caaatattta gaagtaataa
      421 tattgctatt attaagataa aattactgta aaaatccaaa agctatcctc ctagcaacta
      481 tttaaatacc caaaaaaatt acctctagat aatatcatac ctacgttttc acttataaat
      541 tttttcataa aaaaagcgtt tagaggcata atcgttaata cagatggtaa ccaatgtatc
      601 tggtttgaac tgggatatca ccctctccat atatgtatta ctaagactaa tagatactat
      661 aaaagacttg atagttttgc attgattttg cctaatactg agcataggtg tatgctaaac
      721 gatactataa ggagtgtgta cataatgaaa agaattctgt ttatcagttt atcaaattta
      781 ttgttactta ctgcttgtgg gacttctgca tcaaagaaca taccttcaga tacgcaaatt
      841 tcgaatagta tcgattcaac aatttctaca aatgagaaaa attctccggt agaaacttcc
      901 gatataaaag tttctacctc tgcaaaaaac agggtaaaga aactgtcagc acgtctcctt
      961 tatttcaaac aaactctgaa ttagcttctt catcttcttc agcaaataat gatgatagtt
     1021 tcgcgtttac tcctaactaa atgcaacctt tacaaatgct ttacgataac aagcctgagc
     1081 taaatgatcc tgatatcagt tttgcatttt ttgaaatgat tggatcggat gatcttttta
     1141 aaactactag tttgtctatc cgaaaatagg acagttctgg cagtataggt ttttatcgag
     1201 tttctccacc aggcctcgtt acagagacag attctctagg cgaacctttt gaataaatca
     1261 aaaatcatga acaatcactg ccaactaaat aaagtgcctt caaaagcttg gtcttctcgc
     1321 ttttgaaggc actttattta aatctttatg aaactaaagt atgttcatat ttgttgctat
     1381 agttatatag atattctgtt gtttccaact cataaacgtg agtatatttt gccactactt
     1441 ttccgcattt ttctaatatt tcattgcgat cgacgtcatg atattcgtct acgcagatca
     1501 caacacaatt ttctaattta ctgattactt ctccaatcac tttttgttt
//
LOCUS       DADQCX010000202         1524 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.210, whole genome shotgun sequence.
ACCESSION   DADQCX010000202 DADQCX010000000
VERSION     DADQCX010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.210"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            14..1480
                     /locus_tag="J8R83_002831"
     CDS             14..1480
                     /locus_tag="J8R83_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAZ9575920.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          417 a          289 c          324 g          494 t
ORIGIN      
        1 tggggtatag attatggaaa aacagcaaga caagggcttc ttcgggcagc cgaagggatt
       61 gtcaactttg ttcttcactg agatgtggga acgatttagt tattacggta tgcgtgcatt
      121 acttatctat tatatgtacg atacagttgc caacggggga cttggattac cacgagcaac
      181 agcattagct atcatgtcga tctacggatc tttgatctac atgtctagta tcgtcggcgg
      241 atgggtatct gaccgagtgt taggagcaaa acgcactgta ttcttcggtg gagttttcat
      301 tatgcttggc cacatcgtct tggctttacc atttggtgta agtacattgt ttgtttcgat
      361 ggcattgatt attatcggaa ccgccttttt gaaaccaaat gtttctggca tggtcggaca
      421 tctttattca aagactgact tgcgaagaga tgcaggattt tcgatttttt acatgggtgt
      481 caacttaggg gcattattag caccactaat cgttggtaca atcggtcaag aatataacta
      541 tcatttaggg ttctctttag ctgctattgg gatgttcttt ggattattac aatacatcat
      601 ccaaggacgc aagacattag acggagtggg tacaacaccg ccgaatcctt tgacaactga
      661 agaacgtaaa ggattcatcc gtaacttgat catcgcactt gttgttatcg ctgcagtatt
      721 cggcggggca caactaactg gtcatctgac aattgacttt tttgtcaata caatcagtgt
      781 attggggatt atcttaccgt tgtattactt tatcaaaatg ctgacttcaa aagatgtaac
      841 tgctgaagaa aaaccaagag tatgggctta tatcccatta ttccttgcag caatcatttt
      901 ctggtcatta caagaacaag gttcatctat cttagcttta tttgctagtg aacgtacaca
      961 atctacgcta tttggtgtaa cgatccaagc aagctggtat caatcattga atccaatttt
     1021 catctttatt ctgacaccag tattcgtaac gatgtggacg aaacttggtg aacgtcaacc
     1081 atctacagta gtgaaattct ctcttggact tttatttgca ggattatcgt acttgctatt
     1141 gatgttgccg ggtatgcttt atggtacaag tggaaaagta agtccattgt ggttgttggg
     1201 aagtttcttc atcgtggtta ttgctgaatt gtgtctttca ccagttggtt tgtctgtgac
     1261 aacaaaatta gcaccacgag catttgaatc acaaacaatc gctatttggt tcttagctga
     1321 tgcttcttca caagcaatca atgcacaaat tgcacgcttc tacacaccgg gaacagaatc
     1381 tgcttacttc ggtattatcg gtgcagtagc aatcgtcggt ggtatcttgc tatttactgt
     1441 gaaagaacca atcaaaaaac taatgggctc tattcattaa tcaatgaaca taaaaacagg
     1501 aattgcttat ttgcagcagt tcct
//
LOCUS       DADQCX010000203         1480 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.212, whole genome shotgun sequence.
ACCESSION   DADQCX010000203 DADQCX010000000
VERSION     DADQCX010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.212"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            365..919
                     /locus_tag="J8R83_002832"
     CDS             365..919
                     /locus_tag="J8R83_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9575921.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1173..>1480
                     /locus_tag="J8R83_002833"
     CDS             1173..>1480
                     /locus_tag="J8R83_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575922.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     "
BASE COUNT          591 a          156 c          256 g          477 t
ORIGIN      
        1 gaaaagtttg gtagcacggt tattcatatg ctaatttatt tcactttata gtaaggggag
       61 ttcttagtat attgttcaaa cttaaatttc atataattta attatgtaaa ttagctattc
      121 taagaacttc tacggataac tgcccgtcta aaatttaaat aagagcttag aatcttcata
      181 taagtaaggt taattttttt gtacaaaaaa gtcggaatat tctgagttac tgaaatgata
      241 taaaatcata aactaaaccc cttgattttc ttcactttta acagagtata tatataagtt
      301 catgattatg gtaaaatata tatataatca tgaactcaga atatttttaa gaagggaaac
      361 aatagtgagc tataatgtac aaccgttaag gacaaatgaa gagatacaag attttcagtt
      421 ttggctaaga agaacaagta atccagaaag agatagtttt ttatttttgt ttggaatcaa
      481 taatgggtta cgtatgtcag atattatagg attaaaagtt ggagacatac gaggtaaaag
      541 taagcctatt attgttgaac ataaaacagg taagcgaaaa ccgattttta tagataattt
      601 gagagaagag attttattat atactgaagg taaagaagaa aatgattggt tatttccaag
      661 tcggcaacaa ggtcgacata taacaaggga tcgtgtctat cagatatatg cagatatagc
      721 agaaaaatta ggaagagatg atataggaac acatacatta agaaaaactt ttgggtatca
      781 ctactacaag aaaactagag acattgctac cttaatgttt atttttaatc atagctcgca
      841 agcaattaca aaaaggtaca ttggtataac tgaagatgaa ataggggcat cgttacgtgg
      901 ttttaaattg ggaggctaat tgagatatta ggatatattt tttgtgtata atgaaaactt
      961 agaaggtgag attaatgaag ataactgaat tttcggaagt atttaaaacg tttagtaaca
     1021 tttacaatag aataccagag atagaacaaa atgttgtagt tgataatgat tattatatag
     1081 agaatgattt taataaacca agaaaatatg acaacctata caattttata cacaatagaa
     1141 caacaataaa taacaacagt aacactcgag ttttgattaa ttcagcatat tttcatatta
     1201 aatatttaaa gaaatatgag tatgaagaag ttgtattaga ttatgggcta aatagacagt
     1261 catttttaat ttatgcaata aataacggaa atttgccaag caataaaaag aacataatta
     1321 ttgaaacata tgcctatctg gaggggggat ctaaaaaact aattaagtca tgtaatatag
     1381 agtatcaatt atcagtagga gaaattaaat gtgttttcga agaagattta gaacttgact
     1441 taaaaaaaat ttttgccagc attcatgatt atataggttt
//
LOCUS       DADQCX010000204         1451 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.213, whole genome shotgun sequence.
ACCESSION   DADQCX010000204 DADQCX010000000
VERSION     DADQCX010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.213"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1350
                     /locus_tag="J8R83_002834"
     CDS             <1..1350
                     /locus_tag="J8R83_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9575923.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
BASE COUNT          572 a          225 c          314 g          340 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata t
//
LOCUS       DADQCX010000205         1449 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.214, whole genome shotgun sequence.
ACCESSION   DADQCX010000205 DADQCX010000000
VERSION     DADQCX010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.214"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            131..505
                     /locus_tag="J8R83_002835"
     CDS             131..505
                     /locus_tag="J8R83_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAZ9575924.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="J8R83_002836"
     CDS             complement(619..1248)
                     /locus_tag="J8R83_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9575925.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
BASE COUNT          487 a          221 c          255 g          486 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaa
//
LOCUS       DADQCX010000206         1434 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.215, whole genome shotgun sequence.
ACCESSION   DADQCX010000206 DADQCX010000000
VERSION     DADQCX010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.215"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            115..1047
                     /locus_tag="J8R83_002837"
     CDS             115..1047
                     /locus_tag="J8R83_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAZ9575926.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1119..>1434
                     /locus_tag="J8R83_002838"
     CDS             1119..>1434
                     /locus_tag="J8R83_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575927.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLV"
BASE COUNT          629 a          166 c          225 g          414 t
ORIGIN      
        1 ttaaatgatg aaataaatca aaagtatgat gaaacattaa aaaatgtcta ttcttcactt
       61 atcgtttcaa atatagaaga aacttcatct tctgaaataa aaaataagct ttctttgtta
      121 aaattaaaag aaaaggaata tattattgac gatgctgttt ctgtccctct tattttaaat
      181 aaacgagaga aaaataattt aaagaaaaaa atgctcattc catttgattc agaagtgaaa
      241 ggattactca ataaactaac tatttctaat atagactcga ctagggaaaa aatcataaaa
      301 atatttgata aaattaataa tttattcaag aatgacaatg ctgaattaag gaagggtctt
      361 ttagagttta aacttcaaga actagaactt cattactctt atttagtgaa aattaccgaa
      421 gaaaaagaac aacaaaaagc aataaaagaa cagatgatag aagaggaaaa agttcgtaga
      481 gaaattgatc gtgaaaagaa acgtattgat aaagaacaac gtcaattcaa ttctgaaatt
      541 tccaaattaa tcgcatatat gcaaaaagct aatgcagatg tggaaaaaga attatatgca
      601 aataaaattc aagaactgga agaaaaatta aaagaattag aagttatacg tgaaaatgta
      661 ttacaaagag aattaaatac tagagccggt tatgtgtatg taattagtaa tattgggtct
      721 tttggtgaag acatatataa aattggtatg actagaagat tagaacctat ggatagaata
      781 aaagaattga gtagtgcatc ggttccattt gaatttgacg ttcatgcgat gattttttca
      841 gaggacgctc cgtctttgga aactaaattg cataatcatt ttagaaaaca agaagttaat
      901 aaaattaatc aaagaaaaga atttttcaaa gtttcactag acgaaataga gaaagttgtt
      961 ttagaaaatt ataatggaac agtaacattt acaaaattag ctaaagctga acaatataga
     1021 cgatctttag aattgtcaaa agattaaata tataaaaagc cttcgggctt tttcttttaa
     1081 caattaatag gaacgtatat tcgaaaggaa tagaaataat gtggttagaa aaaataaatg
     1141 acaaaaaatt taagtacacc gaacgttata cggatccctt aactgaaaaa aagagaaaag
     1201 tgtccgttac tttatctagc aattcacgcc aagcttggaa tcaagctaac ttacttttga
     1261 atgaaaaaat cgcagaaaaa ataaaacgaa atgaagaatt accactaact tttggagaat
     1321 taaaaactaa atgggatgaa aaatacaagc caactgtaaa agaaagttcc tatcgaacaa
     1381 ctcaggttta tctatcatta atttcaaaat atataaaaga tgatgtactt gtaa
//
LOCUS       DADQCX010000207         1425 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.216, whole genome shotgun sequence.
ACCESSION   DADQCX010000207 DADQCX010000000
VERSION     DADQCX010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.216"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            100..1392
                     /locus_tag="J8R83_002839"
     CDS             100..1392
                     /locus_tag="J8R83_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9575928.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          463 a          292 c          258 g          412 t
ORIGIN      
        1 tgacaccagc atctttttta ttttccaaaa catatagaaa agacaccttg aaatccttta
       61 gaattaattt ggcgaaccaa cccaaaagga ggaatcaaga tgtcttacac tcaccttatc
      121 aaagaaacat tagatattct agacttatca gttactttta acgaaaattg tctcacaaaa
      181 gaaaaataca aagggcaaat ctgtcatatt tatcgtggaa acttgattta tacagcccaa
      241 gaatgcatcc actgtaaaca ccagattgct tcagatattg tgcgttgggg tacaacaacc
      301 gtccggttgt taatgaacga tgtttctgaa taccgtacct acctcgaatt gaaaaagcaa
      361 cgcttcaaat gcaaagcttg tcagcggacc tttgtcgcag atacttctgt tgcgaaaaaa
      421 cattgtttca tcagtgagaa agtccgctgg tctgtcgtga ctcgtctgaa aaaaaatacc
      481 tcaatgacag agatcgccgc tcagaaaaat ctatcggtct cttctgttta ccgtattatg
      541 aagcgatttt atcgtccgtt gaatcctttt cggacaccgt tacctaaggt actttgtttt
      601 gatgaattca aatcagttcg gggtgtttca ggtgctatga gtttcatcat gatggatgga
      661 caaacacagc gcttattgga cattgtcgag aaccgacaac tgcctttttt aaaacgttat
      721 tttagtcatt tttcacgaga aattcgtgaa gcggtcgaat ggatcgtgat tgatatgtac
      781 gctccttatg tatcgctcgt taaaaagctg tttccaaaag cacagctgat tattgaccgg
      841 tttcacatcg tccaacatat tggtcgtacc tttcgcaatc atcgaatcaa agaaacgaac
      901 caactattaa aaagcaaaga acaaaaacac tatcaattag gtaagcaatt aaaaagatac
      961 tggaaacttc ttcaaaaaga tgaacgcaag cttgattata ctcgacgcct ttggcgacct
     1021 ggcttcaaag ctcatttaac agagaccgat attgtggatc gcttactgaa agggagccct
     1081 gctttgcgtg taggctatca gttatatcaa gactttcttt acgctgtaaa ggaacgagac
     1141 tacgtatcgt ttgaagaact acttaccaat aatatcatgc ttcccgaagg ctatcagacg
     1201 accttgagaa cgttccagaa atttctgcca caaatcaaaa atgctttaca acaaagttat
     1261 tcaaatggcc cacttgaatg tctgaacaac catatcaaag tgttaaaacg aaatgcatat
     1321 ggctttcgta gcttttataa tttcaaattg cgcatcatga ttcgtcatgg caacgcattg
     1381 attttcaact aaaaaagatc aagaggaact gatccacttg atctc
//
LOCUS       DADQCX010000208         1417 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.217, whole genome shotgun sequence.
ACCESSION   DADQCX010000208 DADQCX010000000
VERSION     DADQCX010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.217"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            306..1354
                     /locus_tag="J8R83_002840"
                     /pseudo
     CDS             306..1354
                     /locus_tag="J8R83_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180785.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          542 a          170 c          275 g          430 t
ORIGIN      
        1 aggcttacca gcgagataga gatcgacgat ttgttgtttg aattcttttg aataggttct
       61 tcgttgacgt cttggcatga aaaatcctcc agtgtgtttt ttattattct acacacctta
      121 ttttttctgt ctagtctagt gtagccgatt caagttcttc gtgttctctt agacataaaa
      181 attcctcctg gtatgttttc ttctagtcta cacaccttaa tttttctgtc tagttaattg
      241 tagcctatcc agtttggaaa aataaaaaat tatatttcat caacgtttca taaaaggtgt
      301 gtagaatgtt attgaaagta gctataaaat gctattgtgt aaaaaataaa ggaggaataa
      361 tttatgaaaa aatagtacca agaggagcat gcctattact tgcattatgt ttgagcttaa
      421 gcgcagttgg gtgtcaaaaa agtaatgaaa acaataaaat aaaagaagga caatccataa
      481 gttctgaaga ggaaggcatg tcaattaatg caaatggcaa aaatgaaact tttaagccat
      541 cagattatac attggaggca aagaaagaat atgtttatga atatttaggg cttaaattta
      601 aactctcaga caaatttaga aattatatag ctgataaaaa gatagcgatg ttagatgatc
      661 aaagtcctat agataaagaa ctaaagtatg ctattttgac atttgagaaa atgacagaag
      721 aacaaaagaa tgcagttata gaaaagatgg gcgatggata taaaaattgg caaaatgagc
      781 ttgaaagaat tgggactatt ggtatatttg aaaaaaatac atcagaagaa aaaaatctaa
      841 aattataaaa tgtgatactc atactaaaat aggagtttca agtgatggaa aatacgattg
      901 ctatttaagc acaaatagcg gagctgaaag taatcttctt gatgaattaa aaagaactga
      961 gattcaaatt atagataaaa aagaacgtcc taaaaatggt tttgtgctat cagaaaaaac
     1021 tgatttagaa aatacagaag catttaacaa agaatcggtt aaagatttac gtaaactacc
     1081 aacaaaggac ataaatggca aggattttac aagtaaagat tttgagaagt atgatcttac
     1141 tatggtaaat gtatttgcaa cttggtgtac agcttgtgta aaggaaattc ctgatttggt
     1201 tgaggttcag aatgaaatga aaagcaaggg tgtaaatatc gttggagttg ttacagatcc
     1261 tgttgatgat aacggtgaaa acaaggaagc aattgaaaag tcaaagttaa tacatgaaaa
     1321 gacaaaggct tcatatcctt tcttaatgcc agatggaatg gcaacacttt ttttgacaaa
     1381 aattataagg tgttgtgaat gctgcggtgt tatggct
//
LOCUS       DADQCX010000209         1416 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.218, whole genome shotgun sequence.
ACCESSION   DADQCX010000209 DADQCX010000000
VERSION     DADQCX010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.218"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1233)
                     /locus_tag="J8R83_002841"
     rRNA            complement(<1..1233)
                     /locus_tag="J8R83_002841"
                     /product="23S ribosomal RNA"
BASE COUNT          319 a          395 c          273 g          429 t
ORIGIN      
        1 accaatacac ctaaaggtgt actccacagc ttcggtaata tgtttagccc cggtacattt
       61 tcggcgcagg gtcactcgac tagtgagcta ttacgcactc tttaaatggt ggctgcttct
      121 aagccaacat cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg
      181 ggaccttagc tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt
      241 ctgactcccg gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat
      301 gggcccctag tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa
      361 agctatttcg gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca
      421 cctcatcccc gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc
      481 ttcaacctgg acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc
      541 ctattcagac tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt
      601 aactcgccgg ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt
      661 gtaggcacac ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc
      721 tcacggtact ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc
      781 cggattccga cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca
      841 catttcgtct acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct
      901 gaaagaacta ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt
      961 ttcccgtttc gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact
     1021 tagatgtttc agttctctgc gtctacctcg aatgtgctat gtattcacac aatcgtaaca
     1081 tcctattaaa gatgttgggt tcccccattc ggaaatctct ggatcatagc ttacgtacag
     1141 ctccccaaag catatcggtg ttagtcccgt ccttcatcgg ctcctagtgc caaggcatcc
     1201 accgtgcgcc cttattcact taaccttatc aaccttacgg ttgggttttg atccttcttc
     1261 tagcgataga agttagatca agaaaataag caattgaact tattaaaaaa ctctatccag
     1321 ctcacaaatc agcctgtacg gcaaaaagat cgatcgtctc ataaaatcaa agattttatg
     1381 gccgtccgcc tattttgctt caggctaaac aatttg
//
LOCUS       DADQCX010000210         1368 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.219, whole genome shotgun sequence.
ACCESSION   DADQCX010000210 DADQCX010000000
VERSION     DADQCX010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.219"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1361
                     /locus_tag="J8R83_002842"
     rRNA            <1..1361
                     /locus_tag="J8R83_002842"
                     /product="23S ribosomal RNA"
BASE COUNT          368 a          297 c          417 g          286 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg acttaaccaa taggttaa
//
LOCUS       DADQCX010000211         1362 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.220, whole genome shotgun sequence.
ACCESSION   DADQCX010000211 DADQCX010000000
VERSION     DADQCX010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.220"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            82..>1362
                     /locus_tag="J8R83_002843"
     CDS             82..>1362
                     /locus_tag="J8R83_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAZ9575929.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          464 a          262 c          257 g          379 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat ta
//
LOCUS       DADQCX010000212         1346 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.221, whole genome shotgun sequence.
ACCESSION   DADQCX010000212 DADQCX010000000
VERSION     DADQCX010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.221"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(158..1299)
                     /locus_tag="J8R83_002844"
     CDS             complement(join(158..1071,1071..1299))
                     /locus_tag="J8R83_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9575930.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          331 a          270 c          284 g          461 t
ORIGIN      
        1 cggacacgat ttgtgagaat tttttcgaga ttccagcggg tgagtatctc atcgtttcga
       61 ccagcggtca aaccaaaacc gtttgaccgc tgatcgaagc gatgaagttg aaaccctgtg
      121 gaaatctcgc caaaaaaatg taagtggtag ctaggaacta agcttgcaat gccaactcct
      181 ccatctgatt tggtgttaaa tagttgatac tactatggat tcgcttgcga ttgtaaaatc
      241 cttcaatgta ttgaaataac gctaaataag cagcttcaaa gttttcatac gcttttgatg
      301 gatagacttc ttcttttttg agtgaggcgt gaaacgattc gataccggca ttatcgtagg
      361 gacagccctt acgactgaag gagtgccgaa tgttcaattc attcagcttt gcctcatagg
      421 cttcgctagt gtactgagaa cccaaatctg agtggatgat caagttctcg gagggtgttt
      481 ggtttaagag cgcattgtca agggtttcga taaccaattc tttcgtcatc tgcttgccaa
      541 acttccaacc gatgactttc tttgtgtgga ggtcttgaat agtggagagg taggtccagc
      601 catcttttag ggtatgaata taggtaatat ctgtcaccca tttttgattg atcgacgtag
      661 tggtaaaatc ttggtttaac aggtttttac gtccttcact tttaactttc gcttgtttgc
      721 caggcttgta cttcttgagg gtgactgaac gcaagcctaa ttttctcatc agtatttgta
      781 ctttctttaa ggacaaggtc tcgccacggc caacaagaat cttatgaatt ttaggcgcac
      841 catagatacc cttgttttca aagtagattc ctgaaatcaa gcggtttaag cgtttgtttt
      901 ctgattggcg cttggaaggt ttctttttct tccagtcata gtagctggat ttcggtgctt
      961 ccaaaacggt acacatttgt tttacgtcat gatcatgaac atttgattga ataaattcga
     1021 agacatcact catttttact tttgagcgaa tatggttaaa gcctttttta ggatagtgtt
     1081 ttcctcctgc atgcgggcca tttccttttt catcgctagg atttctgcct cagtcatgcc
     1141 ggttgctaca ttctttgtat gaagcttctt ccaacgataa atcgtttgtg tagcgatacc
     1201 atattgcgct gccagttctt cgaccgattg gccagactgg tttaaatcta agatcatctt
     1261 cttaaagtct tcatcaaatt ttttcttggc ttttgccatc gtggacacgt ccttttctta
     1321 gtagttagat tctaccaaat cgtgtc
//
LOCUS       DADQCX010000213         1290 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.222, whole genome shotgun sequence.
ACCESSION   DADQCX010000213 DADQCX010000000
VERSION     DADQCX010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.222"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(15..1154)
                     /locus_tag="J8R83_002845"
     CDS             complement(15..1154)
                     /locus_tag="J8R83_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAZ9575931.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          336 a          281 c          239 g          434 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt
//
LOCUS       DADQCX010000214         1288 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.223, whole genome shotgun sequence.
ACCESSION   DADQCX010000214 DADQCX010000000
VERSION     DADQCX010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.223"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            82..>1288
                     /locus_tag="J8R83_002846"
     CDS             82..>1288
                     /locus_tag="J8R83_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HAZ9575932.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIK"
BASE COUNT          433 a          245 c          248 g          362 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaaga
//
LOCUS       DADQCX010000215         1222 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.224, whole genome shotgun sequence.
ACCESSION   DADQCX010000215 DADQCX010000000
VERSION     DADQCX010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.224"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..587
                     /locus_tag="J8R83_002847"
     CDS             <1..587
                     /locus_tag="J8R83_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575933.1"
                     /translation="VLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKPALGDIP
                     RHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRVPSQLWK
                     ELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIEKSNTQE
                     KKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(584..1180)
                     /locus_tag="J8R83_002848"
     CDS             complement(584..1180)
                     /locus_tag="J8R83_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9575934.1"
                     /translation="MQQNPSIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQE
                     VLDFVRDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLD
                     KFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLV
                     YRSIVQDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT          404 a          196 c          226 g          396 t
ORIGIN      
        1 aagtacttcc tacttttctt gctggaaagc ttggaattga tttatcagat agccagcatt
       61 atgatgaaaa cttagatgat ttaattacaa ctatatttgg tgttaagaga aaaccagcat
      121 taggtgatat acctaggcat attaaaggca gtcctttact acctatagaa cataatgaaa
      181 ataaagatat tgaaatctta ggaattatca ctgataaagt aactgtacct aaaatggatg
      241 gctcaagggg ttctgcatta tataaaattc catttagatt aaatagagta ccaagtcagc
      301 tttggaaaga gttgtttgtt agaaattgga attcaccacc acgatataca acaatgcata
      361 gaccaggaat tgcttctgtt gtagacgatg aaattttact taatggaaca actattgagg
      421 aagtccggga atatcatcgg gaaactttaa aactttgcat tgaaaaaagt aatactcaag
      481 aaaaaaaaat attgctagag gaggaacaaa aaaaagagag agagaatgag cgagtcagat
      541 cacataaaga aagtgttcag aaattagcag atgaattaga gttctagttg atagtcagtt
      601 ctttcttaat tcgatacaca gtttgtctag ttacattata gtctgttgct atttttgaaa
      661 tagcaacacc attctcctgg tcctgaacga tgcttctata aacaaggcga cgttgaggat
      721 cttttgtgtt cgcactgtat aacttaggac gtcctttata gacgccgttt gctttagcaa
      781 tctttatccc ttgtgcctgg cgtcgttttg attcagtacg ctcttgttca gcaatcatgg
      841 ccaagatttg aatgattagg tctttgataa atttatccag gagaggattt ccgattgctt
      901 cagccatgat cggtaaatta gtgataataa gtcgcacatt tttcttcttt agataattta
      961 ctgaatcgat aatctcgtca taattacgtc caagtcgatc gatagcctct acaataaaaa
     1021 tatcttggtc tctaacaaaa tctagaactt cctgaaaaat cggtcgatga gtaatagtcg
     1081 ctccagattg tttctcgatg aaaatttttt cagcaccaaa ttttctcatt tcctcgattt
     1141 gacgttgttc attttgatcg atcgatgggt tctgttgcaa agttttccaa aaaatctatt
     1201 ttagtgtaaa attgagaaaa aa
//
LOCUS       DADQCX010000216         1215 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.225, whole genome shotgun sequence.
ACCESSION   DADQCX010000216 DADQCX010000000
VERSION     DADQCX010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.225"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            414..947
                     /locus_tag="J8R83_002849"
     CDS             414..947
                     /locus_tag="J8R83_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAZ9575935.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          389 a          226 c          225 g          375 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttacc
//
LOCUS       DADQCX010000217         1204 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.226, whole genome shotgun sequence.
ACCESSION   DADQCX010000217 DADQCX010000000
VERSION     DADQCX010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.226"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(418..1110)
                     /locus_tag="J8R83_002850"
     CDS             complement(418..1110)
                     /locus_tag="J8R83_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAZ9575936.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
BASE COUNT          371 a          175 c          132 g          526 t
ORIGIN      
        1 ccaaataaac attattagtt aaagtaaaat gaaaaataat tgatttacgt gtctttatta
       61 taaatatgaa gtcaaaaaaa atcacctata ttttttactt aaaagaaaaa atatagaatt
      121 acaagtcgtt caaaagttta atcacctgtt attattacta actagtttcc atatgttatc
      181 atcataatta cttcttgata ataattcata ttacaaaatt attcggtacc ttttgtcaaa
      241 tcgaaatttt catatcaata ataagcgaga ataataaaaa gactactctt tcgagtagct
      301 atatactgat gtcatcaaaa atagaaaagg aaacggtgtt tagattgtat aatattatga
      361 catttatatt ctatctcatt atctccaaac ataccatttg ttaaattaaa actatatcta
      421 ttggattgta tgttcattta caatttgttg tgctttattt gcggtatcct ctacatcatt
      481 tttagctttt tgaagctttt caatgtaatt attcaaacta ctattttttg acttttcttc
      541 ttctagcttt tgctgagtag cttgcagttg attttgaatg ttattttttt cactcaacat
      601 ttgattaatt tgctggttta aactattaat agtagattgt tcttcattaa atttgttctt
      661 ttcattttgt aaacgattat tccaatcgct atttaatcga tttatttcag ctactttttg
      721 gttaatttcg tctattttcg cattaatttc attttgtttt ccttgcaatt cagagtcttt
      781 tgctgacaat tgattttcta aattagtttt ctctgatact aattgattct tgtcgttttc
      841 taaagatgcc actttttgtt tggaaacttc aatattagtt cttagttgtt caagagtttg
      901 gttgtttgaa gacaattgtg aatttaaaat actaattttt tgctctttat tttctagagc
      961 tgtgtctaat atagttaaat tgttgttgat cttttcaata ttatcttccc ctccccataa
     1021 taaaatatta tcagcatatt gctttccgga gaaaattact aacatcaatc ctataattac
     1081 tccagcatta ataataatct tttttctcac ttttatcttc tccttcaaaa aatttcctta
     1141 aataagttat taaaaattat tttcttcgtc aagctttctt tagacacttt ctgttttttg
     1201 tcta
//
LOCUS       DADQCX010000218         1195 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.227, whole genome shotgun sequence.
ACCESSION   DADQCX010000218 DADQCX010000000
VERSION     DADQCX010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.227"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1076
                     /locus_tag="J8R83_002851"
     CDS             <1..1076
                     /locus_tag="J8R83_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAZ9575937.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DADQCX010000219         1143 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.228, whole genome shotgun sequence.
ACCESSION   DADQCX010000219 DADQCX010000000
VERSION     DADQCX010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.228"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..106
                     /locus_tag="J8R83_002852"
     CDS             <1..106
                     /locus_tag="J8R83_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9575938.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT          428 a          169 c          176 g          370 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaa
//
LOCUS       DADQCX010000220         1139 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.229, whole genome shotgun sequence.
ACCESSION   DADQCX010000220 DADQCX010000000
VERSION     DADQCX010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.229"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..910
                     /locus_tag="J8R83_002853"
     CDS             <1..910
                     /locus_tag="J8R83_002853"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9575939.1"
                     /translation="ILNIRGLSYLPLKKFSRKEIDRAVHELNPDIIHAHDFNASVRAS
                     RYKKQIILSHLHNNPLWLPKLDIRTIIYSLCSSRFNSVIGVSNSVKEEFRYKQLIKDK
                     FVLLPNTVNTERIIKMGNEFVEDDIDILYVGRMAEPKNPIGAINVLENVVKKYSKHLR
                     VVMIGEGPLFDEVKMQIQKRNLTDVIELKGFKSNPYKYMKKSKVLLMPSLWEGFGLVS
                     VEAMLLETPVVAYNVGGLKDIIDETNGFLCGSEVELSNSLMKLLNSEELRKKMGENAA
                     ISAKKFSNMNRYQGVLEKIYVSAALK"
BASE COUNT          420 a          133 c          197 g          389 t
ORIGIN      
        1 tattttaaat attagaggtt taagttactt accattaaaa aaattttcga gaaaagaaat
       61 tgacagagcc gtacatgaat taaacccaga tataattcat gctcatgatt ttaatgctag
      121 tgtaagagca agtagatata agaagcaaat catcctttcc catttgcaca ataatccctt
      181 gtggttacct aaactagaca taagaactat tatatattct ttatgttcgt ctaggtttaa
      241 ttcagtaatt ggtgtttcga attccgttaa ggaagaattt cgttacaaac aattaataaa
      301 agataaattt gtgttgttac ctaacactgt aaatactgaa agaattataa aaatggggaa
      361 tgaatttgtt gaagatgata ttgatatttt atatgtagga cgcatggcag aacctaaaaa
      421 tccaataggt gcaattaatg ttttagaaaa tgtagtaaaa aaatattcaa aacatttacg
      481 tgtcgtgatg attggtgaag gaccattatt tgatgaagtt aagatgcaaa tacaaaaaag
      541 aaacttaaca gatgttattg agttaaaggg attcaaaagt aatccctata agtacatgaa
      601 gaaatctaaa gttctattaa tgccatctct ttgggaaggg tttggcctag tatcagtaga
      661 ggcaatgttg ttagagacgc ctgttgtagc ttataacgta ggaggattga aggatattat
      721 cgatgagaca aatggatttc tgtgtggtag tgaagttgaa ttatctaatt cactaatgaa
      781 gctattaaat tcagaagaac ttagaaaaaa aatgggagaa aatgctgcta ttagtgcaaa
      841 gaaattttct aatatgaatc gttatcaagg agtattagaa aaaatttatg tatctgcagc
      901 tttaaaataa aatatgaatt ataaaaatag agatcaatta gttttacgaa aaataatacc
      961 cattagtatt ttgtttcaat caggaatgat tttttattca ctgatgccct caatagcaat
     1021 tgcagttgtt tcttttttta tgtttttgta ttatatgtgg tgcttaaaaa agtatttttg
     1081 tttagcagat agcttattgt taacatcaat tcttttcatt ccaacatcaa ctatatcta
//
LOCUS       DADQCX010000221         1063 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.230, whole genome shotgun sequence.
ACCESSION   DADQCX010000221 DADQCX010000000
VERSION     DADQCX010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.230"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(38..994)
                     /locus_tag="J8R83_002854"
     CDS             complement(38..994)
                     /locus_tag="J8R83_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575940.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt caa
//
LOCUS       DADQCX010000222          955 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.231, whole genome shotgun sequence.
ACCESSION   DADQCX010000222 DADQCX010000000
VERSION     DADQCX010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.231"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..>955
                     /locus_tag="J8R83_002855"
     CDS             6..>955
                     /locus_tag="J8R83_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAZ9575941.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIE"
BASE COUNT          333 a          125 c          171 g          326 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaa
//
LOCUS       DADQCX010000223          941 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.232, whole genome shotgun sequence.
ACCESSION   DADQCX010000223 DADQCX010000000
VERSION     DADQCX010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.232"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            89..655
                     /locus_tag="J8R83_002856"
     CDS             89..655
                     /locus_tag="J8R83_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9575942.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            800..887
                     /locus_tag="J8R83_002857"
     tRNA            800..887
                     /locus_tag="J8R83_002857"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:832..834,aa:Ser,seq:cga)
BASE COUNT          331 a          144 c          195 g          271 t
ORIGIN      
        1 acgttttgag taaaatgttt gcaaaaaatg ctaaaaatag ggtacaataa aacaacatat
       61 actgcagtaa agaagtgggg gagttttaat gagaagaaaa gtctatacca aggatcaaat
      121 tctaaaagct gcttatgatg ttgttgcaaa ggaagggttt aaaggattta ctgcgagaaa
      181 tattgctaaa aagatgggga tttcgacaca gccgatttat ctggaattca aaaacatgga
      241 agatttaaaa aatacgttgc tggattctat ctttgaacaa ctaaaagaag atgttttccc
      301 tattgaacgt actggtgata aaatcattga tctcggtttg aactatatct actttgcaaa
      361 aaagcatcat agtctttaca tggcattgta cattgatgaa catggggacg gaaagaaaat
      421 gcatgatttt tcatacaatt atttccgtga aatagttaaa gaagatgaaa gatacaatca
      481 attatcggat gaatatgtcg atgctctgca tactggtaca tgggtagcag tgactggctt
      541 agcgtcattg atgtcatcaa acatcatgca tccaacagaa gaacaaatca ttgcactgat
      601 caaacggaca attgactcga ttttagcatt agataatcct gaaataatca gatagtgttc
      661 tatcagtatg aatttgatcg gtaagtccgt tggctgcaaa ctgtcaatgg acttttttgc
      721 taaaaaaagc gatttctgtt atttatctat tagaaatagg cttgacattt cgtgaaaaaa
      781 gtttaaaaat agtacttacg gaaggttggc agagtggtaa tgcaccggac tcgaaatccg
      841 gcgaaccggc taataccggc gcgcaggttc aaatcctgta ccttccttat atcaacgatt
      901 agaggttgtg aagaagctgt cctgcatcaa gtaataagaa c
//
LOCUS       DADQCX010000224          932 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.233, whole genome shotgun sequence.
ACCESSION   DADQCX010000224 DADQCX010000000
VERSION     DADQCX010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.233"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(79..765)
                     /gene="gpmA"
                     /locus_tag="J8R83_002858"
     CDS             complement(79..765)
                     /gene="gpmA"
                     /locus_tag="J8R83_002858"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAZ9575943.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
BASE COUNT          261 a          169 c          179 g          323 t
ORIGIN      
        1 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
       61 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
      121 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
      181 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
      241 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
      301 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
      361 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
      421 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
      481 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
      541 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
      601 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
      661 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
      721 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
      781 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
      841 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
      901 acgaacagtg cccacgcaac tgttcgtttt ta
//
LOCUS       DADQCX010000225          906 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.234, whole genome shotgun sequence.
ACCESSION   DADQCX010000225 DADQCX010000000
VERSION     DADQCX010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.234"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          350 a          106 c          113 g          337 t
ORIGIN      
        1 aacccattag caatatataa aagaaggtat caagagtcac agtgaattta ttccgaaaag
       61 tgaaaagagc aaatataaaa tttaataaaa ataagaacta aataggaaaa cgtagacgta
      121 attttctacg ttttcctttt catatatatt aaatattacg gaaaattata taaactaatt
      181 tagtgttttg tttgtaattc ctaattttgc tccactttta gataattttt aggtctattt
      241 aactcattag acattctatg ctcatttttc tccaaatttg tttcaactct ttcgtactta
      301 attttgcgta tttgaaaatt cttcttttag agtactttta ttacgatact agtatgatat
      361 atatctacag caaacagtta aaatcttcct aaaataagcg aatagcattc ctaaaaccta
      421 taaaattttt agatgaagcg acaagtggac aattaataaa ctacttgaac atgaaattat
      481 ggatcacctt tcaaatttag aaaatggaat tcttatactt attgcgcaac atttattgat
      541 tgcaaaatta tgtgacaaaa agaactagta gaagaaggaa taatggcttg ataataaagt
      601 actacctatt aaaggtagta ctttatttaa tttagtataa attaacatac tactatattt
      661 taggtttcat attatataaa ttaataatat actaccattt gttggtagta taatttaaag
      721 gtaataagtt attcttttat tactatgttt gggttttata gcaaagaaag tttaataaga
      781 gtttggacct agcaaacaat attaatgagg tcattaaatc ttattatctt tagtgatata
      841 atgaaatatc tacacgacaa aattatgatc ttgcgtaaag ttataaaata ttaataaaaa
      901 tatttt
//
LOCUS       DADQCX010000226          850 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.235, whole genome shotgun sequence.
ACCESSION   DADQCX010000226 DADQCX010000000
VERSION     DADQCX010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.235"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            155..394
                     /locus_tag="J8R83_002859"
     CDS             155..394
                     /locus_tag="J8R83_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013646120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAZ9575944.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            443..526
                     /locus_tag="J8R83_002860"
     CDS             443..526
                     /locus_tag="J8R83_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HAZ9575945.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            651..>850
                     /locus_tag="J8R83_002861"
     CDS             651..>850
                     /locus_tag="J8R83_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAZ9575946.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLS"
BASE COUNT          354 a          111 c          140 g          245 t
ORIGIN      
        1 attgatttta tatctttctc aaaataaaca taaaagtcct ttaaacaggg cttttatata
       61 ttaatcactt atcacaaatc acaaatcact tatcacaaat cacaagtgat ttgtgattgt
      121 tgatgataaa ataagaagga atagaaagaa gtgagtgatt gtgggaaatt taggcgcaca
      181 aaaagaaaaa cgaaatgata caccaatcag tgcaaaaaaa gatataatgg gagataagac
      241 ggttcgtgtt cgtgctgact tgcaccatat cataaaaatc gaaacagcaa agaatggcgg
      301 aaacgtaaaa gaagttatgg aaataagact tagaagcaaa cttaagagtg tgttgatagt
      361 gcattatctt aaaattttgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
      421 aattaagaag gagggattcg tcatgttggt attccaaatg cgttatgtag ataaaacatc
      481 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac attagattaa
      541 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
      601 gtttaacttc tgtatttgtt tatagatgta atcacttcag gagtgattac atgaacaaaa
      661 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
      721 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
      781 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
      841 tcaacttatc
//
LOCUS       DADQCX010000227          846 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.236, whole genome shotgun sequence.
ACCESSION   DADQCX010000227 DADQCX010000000
VERSION     DADQCX010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.236"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(36..236)
                     /locus_tag="J8R83_002862"
     CDS             complement(36..236)
                     /locus_tag="J8R83_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9575947.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          272 a          145 c          134 g          295 t
ORIGIN      
        1 tttctttcga aaagacggtt aaaagtcaat ttttattaag ctttaacaat gtttgttgct
       61 tgagggccac gttgaccatc ttcaacatcg taagacactg cttggccttc ttctaaagtt
      121 ttgaagccgt caccttggat agctgaaaaa tgtgcaaata catcatttcc atcttcacca
      181 gtgataaagc caaaaccttt gtctgcgttg aaccatttta ctgtaccgtt attcataaat
      241 aaattcctcc tgatacgtat caatgtacgt tttttcgttg caataaatat ttgataggca
      301 aaaggagttt tatctatgta gatatatcgc tcaaattacg tttcaaaata gattactcat
      361 ttaatatatc atgctttttc taataacaca aggataatgc aatgaaatat aaaattcatt
      421 gtcttctatt gtcttcgaat cgaagaaaaa gttgaataac cgcgattgat tcactttttg
      481 ttttcttgtt tatttgcttt tatctgcaac ttttgacttt aaaatttctt aactatgaaa
      541 acctttcaat tggtggtata cttataaatg gaatttcgtt atcaacgcgt tcgttgcctt
      601 tcagcaagta tttaaagaaa ggagaatggc tatgacattc tataacaaag atatacaata
      661 tcgagtaacc ttggatacag atttgaatct atttgtcgtt tttgacaaag aaaataccaa
      721 tcatgtagcg acaggtgtta cgatcgaaca agcagtgcaa gaattaaaaa aatctgcata
      781 aggagtggaa accctcatat ggacgattct cgttcttctc tttaaacgca tctactggta
      841 gataac
//
LOCUS       DADQCX010000228          805 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.237, whole genome shotgun sequence.
ACCESSION   DADQCX010000228 DADQCX010000000
VERSION     DADQCX010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.237"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..672
                     /gene="tnpB"
                     /locus_tag="J8R83_002863"
     CDS             <1..672
                     /gene="tnpB"
                     /locus_tag="J8R83_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAZ9575948.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          297 a          126 c          150 g          232 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgtca
//
LOCUS       DADQCX010000229          774 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.240, whole genome shotgun sequence.
ACCESSION   DADQCX010000229 DADQCX010000000
VERSION     DADQCX010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.240"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(22..618)
                     /locus_tag="J8R83_002864"
     CDS             complement(22..618)
                     /locus_tag="J8R83_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAZ9575949.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          294 a          146 c          119 g          215 t
ORIGIN      
        1 actaatttta caaaataaat attatccaag aagaccactt agatattgac ctccataaat
       61 caaggccata ctatataaga aaatcgacag tggtttagca atcaaaatga ttagtgtata
      121 tcgtttcact gacatgtttg tcaatccagc catcaaacat aacgcatcgt caggagcaac
      181 tggaagaaaa atagctagag caaacagctt ctcaaaacgg ttttgattat ccagccagcc
      241 aatatatttg ttatatgtct tatcgctaat catggaaagt atgaatggct ttccataacg
      301 acgccctagc agaaaaatga taatcgaacc aatgcagatt ccaatatagt tatagataaa
      361 tccagcataa gggccaaata tcaggacacc agctgcagta ctgatccctc caggaatgat
      421 tggaataact acttgcagga tttggatgaa gacaaaaata atcggtccta aaatgatgga
      481 atcacctact aatcctctta acgcattcaa atctttgaaa acacctaaat taataaaata
      541 aatcgtcagc gcgattgata ggcctaatcc gataatggat atgaaattta tcagttttcg
      601 agaggcagca atattcatta ttcatcaact ccttagaggt tctttgttaa ctatacttta
      661 ctagaaaagc aactaactgc gccatttttt gatatgacag aaaacaaaca attttgtaag
      721 ttcatcataa gtataaaaga ttgatctcaa aaaaacatcc aactaaagac ttat
//
LOCUS       DADQCX010000230          763 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.241, whole genome shotgun sequence.
ACCESSION   DADQCX010000230 DADQCX010000000
VERSION     DADQCX010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.241"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(237..761)
                     /locus_tag="J8R83_002865"
     CDS             complement(237..761)
                     /locus_tag="J8R83_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575950.1"
                     /translation="MIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVE
                     LDVNNYRELYVFNSLDVEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKC
                     FESAVVKFPQFKLNPAASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKK
                     AFKIKTIGTAPNFK"
BASE COUNT          260 a          102 c           85 g          316 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact tggcagtata
      541 tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa catctaaact attaaaaaca
      601 tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg aacaatagat
      661 cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata gcacatatta
      721 agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DADQCX010000231          748 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.242, whole genome shotgun sequence.
ACCESSION   DADQCX010000231 DADQCX010000000
VERSION     DADQCX010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.242"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            320..>748
                     /locus_tag="J8R83_002866"
     CDS             320..>748
                     /locus_tag="J8R83_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HAZ9575951.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKS"
BASE COUNT          281 a           83 c          123 g          261 t
ORIGIN      
        1 gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt gaactaatag
       61 agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat agttggttat
      121 tataaaatag taatatagct gatttggatt caattcatat ttatttataa atcaaaaata
      181 cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta cttacttaaa
      241 ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc agtgaattta
      301 taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt tagacggtac
      361 tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga aacatttacc
      421 ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta ataatattct
      481 caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg gatttgatgg
      541 agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa ttgattctgt
      601 cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat ctcagaatta
      661 taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta tcaaagagct
      721 aaactatgag cttgagtatg aaaaatct
//
LOCUS       DADQCX010000232          735 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.243, whole genome shotgun sequence.
ACCESSION   DADQCX010000232 DADQCX010000000
VERSION     DADQCX010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.243"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            27..>735
                     /locus_tag="J8R83_002867"
     CDS             27..>735
                     /locus_tag="J8R83_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9575952.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          260 a          127 c          139 g          209 t
ORIGIN      
        1 caaagaatta taaggagtga gtacaaatga cctataccca tcttacaacg gatgaacttg
       61 taataataga gtcttatttc aaaatgaatc aatctgttgc taaaactgcc cattgcttga
      121 atcgttcaag acaaacgatc cataaagtat atctgttctt caagcaagga aaatcagcct
      181 tagaatatta tcaacagtat aagaaaaaca aatcaaactg tggtagacgt ccgcttgttt
      241 tacccgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg acacccgatg
      301 tgattgttgg tcgtgcagcg tttcctatta gttgttctgc tcgtaccatt tatcgtatgt
      361 tcaaaaaggg gctatttgat tcttctgact taccgatgaa aggcaagcgt aaaccgaatg
      421 gacatcaaga aagacgtgga aaacaaactt tccgccgctc tattcatgaa cgtgaaaagg
      481 attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc gtaggtctga
      541 aacataaaag tgctgtaatt accttagttg aacgattatc aaaagttatc atcacattga
      601 aaccgtgtgg tagacaagcg attgatattg aaaaaaaatt aaatcaatgg tttgaatctg
      661 taccgaaaaa cctattcaaa tccatcactt ttgattgtgg aaaggaattt tcaaattgga
      721 aacagatcag taatg
//
LOCUS       DADQCX010000233          731 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.244, whole genome shotgun sequence.
ACCESSION   DADQCX010000233 DADQCX010000000
VERSION     DADQCX010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.244"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            119..448
                     /locus_tag="J8R83_002868"
     CDS             119..448
                     /locus_tag="J8R83_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9575953.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            438..725
                     /locus_tag="J8R83_002869"
     CDS             438..725
                     /locus_tag="J8R83_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9575954.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKIIPVLLCGTHEKFYEQLKKLI"
BASE COUNT          283 a           80 c          138 g          230 t
ORIGIN      
        1 gttgaaattt attcagcaag gacgcattac gagtcacagt aattacttgt aaatacatta
       61 tctcgtggta taatgtattt actaagtaat tacatactgt tagaaatgag ggatttaaat
      121 gattacaaaa acaagaaaac aaggcaattc aatcatgttg acagtaccta aagattttaa
      181 tgttcctaat ggagtcgaag ttgaagcaaa gttggtagag aatggtattc tttatgaatt
      241 tgttgaacca caaaaagaat tttatgattt tagcgaagat attttgtctg atataattgc
      301 agaaggctac gataaagatg agattcttgt agaatttaag aatagaaaaa acaaaatgca
      361 ttcttccttt agagatattg ctgaagatac acttactaat tctaaagtaa tgactaaaga
      421 ggagttggca acagaaattg gcttatgaaa tcgttccttc aaaacatgtc attaagtatt
      481 taaaaaagct aaaagagaag ccattgaaag aaaaattttt gaatttaatt tatgatgaaa
      541 ttgcgattga tccatataag ggtgaacaaa aaactgggga tttatcaggt atttggtcta
      601 gtgggtttaa atatgcgggc acaacatata gagtagctta cgagattata gaaaacaaga
      661 ttattccagt attgttatgt ggaacgcatg aaaaatttta tgaacagttg aaaaaattaa
      721 tctagtgatt t
//
LOCUS       DADQCX010000234          708 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.245, whole genome shotgun sequence.
ACCESSION   DADQCX010000234 DADQCX010000000
VERSION     DADQCX010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.245"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            38..127
                     /locus_tag="J8R83_002870"
     tRNA            38..127
                     /locus_tag="J8R83_002870"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Ser,seq:gga)
     gene            142..213
                     /locus_tag="J8R83_002871"
     tRNA            142..213
                     /locus_tag="J8R83_002871"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:175..177,aa:Glu,seq:ttc)
     gene            229..301
                     /locus_tag="J8R83_002872"
     tRNA            229..301
                     /locus_tag="J8R83_002872"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:262..264,aa:Val,seq:tac)
     gene            311..383
                     /locus_tag="J8R83_002873"
     tRNA            311..383
                     /locus_tag="J8R83_002873"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Asp,seq:gtc)
     gene            419..494
                     /locus_tag="J8R83_002874"
     tRNA            419..494
                     /locus_tag="J8R83_002874"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:452..454,aa:Phe,seq:gaa)
     gene            496..576
                     /locus_tag="J8R83_002875"
     tRNA            496..576
                     /locus_tag="J8R83_002875"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:530..532,aa:Tyr,seq:gta)
     gene            583..656
                     /locus_tag="J8R83_002876"
     tRNA            583..656
                     /locus_tag="J8R83_002876"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:615..617,aa:Trp,seq:cca)
BASE COUNT          158 a          163 c          196 g          191 t
ORIGIN      
        1 ctcattttga gaaagagtat tgagcttctt tcactctgga gagttgtccg agaggccgaa
       61 ggagcatgat tggaaatcat gtagatggtg ccaaactgtc tcaagggttc gaatccctta
      121 ctctccgtag caaatttacc tggcccgttg gtcaagcggt taagacaccg ccctttcacg
      181 gcggtaacac gggttcgaat cccgtacggg tcattttaat tgaatgttgg aggtttagct
      241 cagctgggag agcatctgcc ttacaagcag agggtcagcg gttcgatccc gttaacctcc
      301 ataatgaact ggttccgtgg tgtaggggtt aacatgcctg cctgtcacgc aggagatcgc
      361 gggttcgatt cccgtcggaa ccgtcgttct tgttattcaa ttaataattt taaaatatgg
      421 cgcggtagct cagttggtag agcaacggat tgaagctccg tgtgtcggca gttcgattct
      481 gtcccgcgcc accatggagg agtagcgaag tggctaaacg cgacggactg taaatccgtt
      541 ccttagggtt cagtggttcg aatccactct cctccatttt ataggggcat agtttaaagg
      601 tagaacagcg gtctccaaaa ccgttagtgt gggttcaatt cctgctgccc ctgccatggc
      661 gaatgtggcg aagtggttaa cgcaccggat tgtggctccg gcattcgt
//
LOCUS       DADQCX010000235          699 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.246, whole genome shotgun sequence.
ACCESSION   DADQCX010000235 DADQCX010000000
VERSION     DADQCX010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.246"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..625)
                     /locus_tag="J8R83_002877"
     CDS             complement(<1..625)
                     /locus_tag="J8R83_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9575955.1"
                     /translation="MANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQ
                     IKDNINVNLESDSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLL
                     ISILFSAIISLIYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDL
                     YSTLLRTIDDLEFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILE"
BASE COUNT          232 a           89 c           63 g          315 t
ORIGIN      
        1 tttccagtat tattttaaga ctagcaagag gggttttaag ttcatgggat gcacctttaa
       61 aaaagtcata ttttaacttt tctaatttta aaatttcttt atttttaaat tccaaatcgt
      121 caattgttct taataaagta gaatacaaat cattaatttg ttgttttaat tctccaactt
      181 catcattaga gctaactttt aaactcattt ttttatcaag tttcatcatt ttatcagtaa
      241 caatttttat ttcttgtata ttatttttta ttgattttgc ataaattaaa gaaataatag
      301 cagaaaataa aattgatatt aataaagaat atggtaaaaa tttaaggctt aaatctttcg
      361 catctttttg catatcagct gtagaaacaa attgtagatt tgttttttta ccatcattaa
      421 gctttatttc tctttcttca attatcaaag aattactatc actttctaaa ttaacattta
      481 tattatcttt gatttgtatt tcattcttat tatttttttc ttttatgaat acttttattt
      541 cactactctt ggaataaaac tccaaagttt gttctatata ttttatttct tttccattca
      601 tattactaga aatttcattt gccatattat gaatcttttc ttttctcgtc tccaaatatg
      661 ttttaggaaa gataaaaaaa attaatgaat gaactaata
//
LOCUS       DADQCX010000236          696 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.247, whole genome shotgun sequence.
ACCESSION   DADQCX010000236 DADQCX010000000
VERSION     DADQCX010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.247"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(53..628)
                     /locus_tag="J8R83_002878"
     CDS             complement(53..628)
                     /locus_tag="J8R83_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9575956.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DADQCX010000237          630 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.248, whole genome shotgun sequence.
ACCESSION   DADQCX010000237 DADQCX010000000
VERSION     DADQCX010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.248"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>630
                     /locus_tag="J8R83_002879"
     rRNA            <1..>630
                     /locus_tag="J8R83_002879"
                     /product="16S ribosomal RNA"
BASE COUNT          156 a          144 c          196 g          134 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct
//
LOCUS       DADQCX010000238          560 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.249, whole genome shotgun sequence.
ACCESSION   DADQCX010000238 DADQCX010000000
VERSION     DADQCX010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.249"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            142..399
                     /locus_tag="J8R83_002880"
     CDS             142..399
                     /locus_tag="J8R83_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575957.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          236 a           68 c           78 g          178 t
ORIGIN      
        1 tttctgtcca cgttcatttt actccaaagt tttcctcatt tcaaaagaaa atcacagaat
       61 acacgaagaa gcgtttctat ttgtataaac tatatcaaag ttctatactt aaattatcaa
      121 ataaaaagga cgtgaagata aatgtcaaat ttagaaaaca aagaagaaaa agttgtaaac
      181 aaaattgttt ctgttgtcaa taaactggat aaagagttag acgaacttga tacgttatct
      241 gaaaatccag aaaaaaaaca taacctaaaa aaatggttag ttgaacgaaa ggctattcat
      301 gaaattaaaa aagttcttca tgaagctgat aaatatgaaa aatatgatga aaaagaactt
      361 gataaagaat ttaaagaaat caatgactta ttactataat tgatttatac gactcatttt
      421 tgagtcgtca gactgcaaac aacactctaa atttaggagt ttgtctacag tctgaataaa
      481 ttttaaattt attgtccata atgttattat gaatttatag cattaagaaa agagataaga
      541 ctttacattt ttttaggaat
//
LOCUS       DADQCX010000239          555 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.250, whole genome shotgun sequence.
ACCESSION   DADQCX010000239 DADQCX010000000
VERSION     DADQCX010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.250"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(82..171)
                     /locus_tag="J8R83_002881"
     tRNA            complement(82..171)
                     /locus_tag="J8R83_002881"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(133..135),aa:Ser,seq:tga)
     gene            complement(195..268)
                     /locus_tag="J8R83_002882"
     tRNA            complement(195..268)
                     /locus_tag="J8R83_002882"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(232..234),aa:Ile,seq:cat)
     gene            complement(282..355)
                     /locus_tag="J8R83_002883"
     tRNA            complement(282..355)
                     /locus_tag="J8R83_002883"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(319..321),aa:Met,seq:cat)
     gene            complement(383..455)
                     /locus_tag="J8R83_002884"
     tRNA            complement(383..455)
                     /locus_tag="J8R83_002884"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(420..422),aa:Ala,seq:tgc)
     gene            complement(475..548)
                     /locus_tag="J8R83_002885"
     tRNA            complement(475..548)
                     /locus_tag="J8R83_002885"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(512..514),aa:Pro,seq:tgg)
BASE COUNT          146 a          156 c          133 g          120 t
ORIGIN      
        1 ggagcaggat ttgaacctac gaccttcggg ttatgagccc gacgagctac cagactgctc
       61 catcccgcga taatatgaaa aaggaggata agggattcga acccttgcac ggttttaccc
      121 gcctgacggt tttcaagacc gttcccttca gccggacttg ggtaatcctc catatgaaac
      181 ttacaacgcc acaatggacc ttgtaggact cgaacctacg accggacggt tatgagccgt
      241 ctgctctaac caactgagct aaaggtccag gctcttaaaa atcgcggcgg aggggatcga
      301 acccccgacc tcccgggtat gaaccggacg ctctagccag ctgagctaca ccgcgaaaaa
      361 gatattcatt atttaaatga aatggagcct agcgggatcg aaccgctgac ctcctgcgtg
      421 caaagcaggc gctctcccag ctgagctaag gccccgtgtt taaatttata attatcggga
      481 agacaggatt cgaacctgcg accccttggt cccaaaccaa gtgctctacc aagctgagct
      541 acttcccgtt taatt
//
LOCUS       DADQCX010000240          554 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.251, whole genome shotgun sequence.
ACCESSION   DADQCX010000240 DADQCX010000000
VERSION     DADQCX010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.251"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            129..527
                     /gene="spxA"
                     /locus_tag="J8R83_002886"
     CDS             129..527
                     /gene="spxA"
                     /locus_tag="J8R83_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAZ9575958.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          196 a           87 c          110 g          161 t
ORIGIN      
        1 ttttaaaaaa attatgaaaa aaaggtagct atttaaaagt tgattatgta taatagaaac
       61 agatgggaga ttattatgat cttctgttac aaaaaagtga ttcttatcac gaaaaggagt
      121 ggtgcacgtt gttaacatta tatacttccc caagttgtac ttcctgcaga aaggctcgtg
      181 cgtggttgca agaacatcag attccatttg ttgaacgtaa tattttttca gaaccattga
      241 acagttctga attaaaagcg attttacaaa tgacagaaga cggaacagaa gaaatcatct
      301 cgacacgttc caaagtattc caaaaactga acatggattt agatgatctg ccgttacaag
      361 aattattgga acttgtgcaa aacaatcctg gattgcttcg ccgtccaatc atgattgatg
      421 ataaacgtct gcaagttggt tttaatgaag atgaaattcg tcggttccta ccgcgcgatg
      481 tacgacaatt agaattacgt caagcacaat tgatggctgg attatagaag gataatacga
      541 aacttggaaa agac
//
LOCUS       DADQCX010000241          549 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.252, whole genome shotgun sequence.
ACCESSION   DADQCX010000241 DADQCX010000000
VERSION     DADQCX010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.252"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>549
                     /locus_tag="J8R83_002887"
     CDS             <1..>549
                     /locus_tag="J8R83_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAZ9575959.1"
                     /translation="CTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKNL
                     DKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFIP
                     WILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHLY
                     DNPVGVLTNNPPFDYQLFNLNN"
BASE COUNT          196 a           81 c          102 g          170 t
ORIGIN      
        1 gtgtaccgca atcacttatg caacgaaaga ccattatttt ggaaggaatt ttgattatga
       61 gatgtcttat aatgaagtgg tcactattac tccaagaaat tatcgtttcg attttagaaa
      121 ggtaaaaaat ttagataaac attatgcaat gataggaata gcagctgggg tatccaacta
      181 tccactctat tatgaggcta caaatgaaaa agggttgagt atggcaggac tgaattttcc
      241 tggcaatgct gattataaag aattacaaga aggaaaagat aacgttgcac catttgagtt
      301 tattccatgg atactagggc aatgctcaac catagacgaa gctaaagaat tattggctac
      361 tatcaatcta gtcaatatcg attttagtga aaaactaccc ttgtcacctt tacactggtt
      421 attagctgat aaagaaaaat cgatagtaat tgaaagtatg aaagatggac ttcatttata
      481 tgataatcct gtcggtgtgt tgacaaataa tccgccattt gattatcaat tatttaatct
      541 gaacaatta
//
LOCUS       DADQCX010000242          535 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.253, whole genome shotgun sequence.
ACCESSION   DADQCX010000242 DADQCX010000000
VERSION     DADQCX010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.253"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          171 a           92 c           65 g          207 t
ORIGIN      
        1 ttttgaagtt tttttcgata gaatcaagct tcgcaagtgg ttctttttta acgactcagt
       61 tatcttatca tgtcgttagt aacatgtcaa taactatttt ttaaattttt tagaaatgtg
      121 atataacatc cacttcagaa tcaacgctgt taaatttatc atgtatttct tccttggtca
      181 actataaatt aagcattact ttgtgaaatg atttttcgat caattattat tattcgttat
      241 acaaccgttt tcaacatatt ttgaaaataa aatgcactaa aaaactatct ttagcagaac
      301 atttcattgt attttttgga ccaaacaata aaaaaagaag tttgaaaaaa attcaaactt
      361 ctttgttcgc ttaatctgta ttttagaaga aaggcactcc ctctacttcg taagttccaa
      421 gaacagagcg catttgacct ggttcttccc aaatatatcc ttcgcctaat tcttctcttt
      481 gattcttttg ttcagtttca aagacaaaca acggaacatt ttcctcttta atatg
//
LOCUS       DADQCX010000243          533 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.254, whole genome shotgun sequence.
ACCESSION   DADQCX010000243 DADQCX010000000
VERSION     DADQCX010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.254"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(170..>533)
                     /locus_tag="J8R83_002888"
     CDS             complement(170..>533)
                     /locus_tag="J8R83_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAZ9575960.1"
                     /translation="VEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVN
                     SVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNDLSTVT
                     YEQVLSIFNSYLLFNGRK"
BASE COUNT          154 a           99 c          102 g          178 t
ORIGIN      
        1 gggtcccgag cgcttagtgg gaatttgtac cccttatcga tacaaattcc tcgtaggcgc
       61 tagggacctc tttagcttct tggaagctgt cagtagtata tctaataatt tatctccatt
      121 ccctttagta acgtgtaact ttccaaattt aaaaaagcga ctcatagaat tatttcctcc
      181 cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta acggtactta
      241 aatcgtttac tttggcgtgt ttcattgctt gatgaaactg atttttagta aacagttgac
      301 gatattctcg attgacccat tttgaaacaa agtacgtata tagcttccaa tatttatctg
      361 gaacatctgt ggtatggcgg gtaagtttta ttaagacact gtttactttt ggtttaggat
      421 gaaagcattc cgctggcagc ttaagcaatt gctgaatcga gacttgagtg tgcaagagca
      481 accctagtgt tcggtgaata tccaaggtac gcttgtagaa tccttcttca aca
//
LOCUS       DADQCX010000244          530 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.255, whole genome shotgun sequence.
ACCESSION   DADQCX010000244 DADQCX010000000
VERSION     DADQCX010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.255"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(7..92)
                     /locus_tag="J8R83_002889"
     tRNA            complement(7..92)
                     /locus_tag="J8R83_002889"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Leu,seq:taa)
     gene            complement(109..180)
                     /locus_tag="J8R83_002890"
     tRNA            complement(109..180)
                     /locus_tag="J8R83_002890"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(146..148),aa:Gly,seq:gcc)
     gene            complement(192..264)
                     /locus_tag="J8R83_002891"
     tRNA            complement(192..264)
                     /locus_tag="J8R83_002891"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(229..231),aa:Thr,seq:tgt)
     gene            complement(282..363)
                     /locus_tag="J8R83_002892"
     tRNA            complement(282..363)
                     /locus_tag="J8R83_002892"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(327..329),aa:Leu,seq:tag)
     gene            complement(371..443)
                     /locus_tag="J8R83_002893"
     tRNA            complement(371..443)
                     /locus_tag="J8R83_002893"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(408..410),aa:Lys,seq:ttt)
     gene            complement(447..519)
                     /locus_tag="J8R83_002894"
     tRNA            complement(447..519)
                     /locus_tag="J8R83_002894"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(484..486),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          115 t
ORIGIN      
        1 ttgaaatgcc gaggaccgga atcgaaccgg tacggtgatc actcaccgca ggattttaag
       61 tcctgtgcgt ctgccagttc cgccaccccg gcgcgattgc tttggcaaag cggaaaacgg
      121 ggttcgaacc cgcgaccccc accttggcaa ggtggtgctc taccactgag ctatttccgc
      181 gtgtttaaag atgccggcta aaggacttga accctcgacc ctctgattac aaatcagatg
      241 ctctaccaac tgagctaagc cggcatgtaa aacttaaatt atgcgggtga agggacttga
      301 acccccacgc cgtaaggcgc tagatcctaa atctagtgcg tctgccaatt ccgccacacc
      361 cgcaaaaata tgagccgtac agggctcgaa cctgtgaccc tctgattaaa agtcagatgc
      421 tctaccaact gagctaacgg ctcatatgga ggttaacggg atcgaaccgc tgaccctctg
      481 cttgtaaggc agatgctctc ccagctgagc taaacctcca tggataactt
//
LOCUS       DADQCX010000245          510 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.256, whole genome shotgun sequence.
ACCESSION   DADQCX010000245 DADQCX010000000
VERSION     DADQCX010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.256"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..434)
                     /locus_tag="J8R83_002895"
     CDS             complement(<1..434)
                     /locus_tag="J8R83_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9575961.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
BASE COUNT          146 a           85 c           80 g          199 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc
//
LOCUS       DADQCX010000246          499 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.257, whole genome shotgun sequence.
ACCESSION   DADQCX010000246 DADQCX010000000
VERSION     DADQCX010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.257"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            107..>499
                     /locus_tag="J8R83_002896"
     CDS             107..>499
                     /locus_tag="J8R83_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAZ9575962.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTP"
BASE COUNT          193 a           86 c           81 g          139 t
ORIGIN      
        1 agagtataaa atattttgtg taaatgaaaa aatccataca aaaaaggaag tcccttctgt
       61 agaataaagt taacgacaac caattcacag aaaagaggac ttccctatga atgattttac
      121 tacagaaatt gtgcaaactc tagtcactaa aggcgattta aatgaattat tccgttcgca
      181 cttagaaaaa gcgataaaca cactcctacg gactgaatta acggcttttt tagattacga
      241 aaaatatgat cgcactggtt ttaattcagg taattcgaga aacggttctt actttcgatc
      301 aatcaaaacc gaatatggtg aattaacatt ggaaatacct agagatcgta atggtgagtt
      361 taaacaacaa actttaccag cctacaaaag aacaaacgat acattggaaa ccactattat
      421 ccatttattc gaaaaaggtg ttacgatgtc tgaaattgct gatttgatcg aaaaaatgta
      481 cggtcatcac tatactcca
//
LOCUS       DADQCX010000247          489 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.258, whole genome shotgun sequence.
ACCESSION   DADQCX010000247 DADQCX010000000
VERSION     DADQCX010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.258"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..414)
                     /locus_tag="J8R83_002897"
     CDS             complement(<1..414)
                     /locus_tag="J8R83_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575963.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFF"
BASE COUNT          186 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaacggc tttccaaatg atgaaatacc taaatctaac ttattaagaa agttgaaatt
       61 tttatattca ggaaaccatt tattaatttc atgtgcagca cgtaatgcat tccctggagt
      121 tgtcaaagag aaaattaatt ctgctaagct tattattgaa aatactgata acttataatt
      181 atatcgtcca ttgacaatca aatataaact aactatactt gttagaacaa aaaaacaggc
      241 gttgacttgt tcttgattag ttaaaaatat caataaagga atacttaccc aatatatttt
      301 tctatttatt tcttctcctc ttaagagttg aaaaaacgga taaaaagtta gtaaactaaa
      361 tgctactggc cactgatagt tcaaggtggt tgctctccaa ccggtttccc ccattactgt
      421 caatggtatt aaacagtata tagagcaaac caataataaa tttttaacat ttattttctc
      481 aaaaacata
//
LOCUS       DADQCX010000248          469 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.259, whole genome shotgun sequence.
ACCESSION   DADQCX010000248 DADQCX010000000
VERSION     DADQCX010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.259"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(76..147)
                     /locus_tag="J8R83_002898"
     tRNA            complement(76..147)
                     /locus_tag="J8R83_002898"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(112..114),aa:Glu,seq:ttc)
     gene            complement(159..232)
                     /locus_tag="J8R83_002899"
     tRNA            complement(159..232)
                     /locus_tag="J8R83_002899"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(196..198),aa:Ile,seq:gat)
     gene            complement(245..315)
                     /locus_tag="J8R83_002900"
     tRNA            complement(245..315)
                     /locus_tag="J8R83_002900"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(281..283),aa:Gly,seq:tcc)
     gene            complement(320..392)
                     /locus_tag="J8R83_002901"
     tRNA            complement(320..392)
                     /locus_tag="J8R83_002901"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(357..359),aa:Phe,seq:gaa)
     gene            complement(396..468)
                     /locus_tag="J8R83_002902"
     tRNA            complement(396..468)
                     /locus_tag="J8R83_002902"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(433..435),aa:Asp,seq:gtc)
BASE COUNT          146 a          127 c          103 g           93 t
ORIGIN      
        1 aaagataact ctgctaagct ttttaaaatc attctttcag ataaaaagaa aaagatactc
       61 aaaaagtatc ttccatgacc cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg
      121 gtgtcttaac cgcttgacca acgggccaat aaaataaatg ggcctaaatg gactcgaacc
      181 atcgacctca cgcttatcag gcgtgcgctc taaccagctg agctataggc ccataaaaac
      241 taaaagcggg tgacgagaat cgaactcgcg acaacagctt ggaaggctgt ggttttacca
      301 ctaaactaca cccgcataat ggcgcgggac agaatcgaac tgccgacaca tggagcttca
      361 atccattgct ctaccaactg agctaccgag ccaaacggtt ccgacgggaa tcgaacccgc
      421 gatctcctgc gtgacaggca ggcatgttaa cccctacacc acggaacca
//
LOCUS       DADQCX010000249          462 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.260, whole genome shotgun sequence.
ACCESSION   DADQCX010000249 DADQCX010000000
VERSION     DADQCX010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.260"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          158 a           63 c           64 g          177 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ct
//
LOCUS       DADQCX010000250          456 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.261, whole genome shotgun sequence.
ACCESSION   DADQCX010000250 DADQCX010000000
VERSION     DADQCX010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.261"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..452
                     /locus_tag="J8R83_002903"
     CDS             <1..452
                     /locus_tag="J8R83_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9575964.1"
                     /translation="KLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAAC
                     PNLRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNAL
                     HYSYSNGPLECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          164 a           91 c           80 g          121 t
ORIGIN      
        1 aaaaattgaa gcgctattgg aaactcctac aaaaagaaga agcaaagtta aactatgaaa
       61 aacgggtttg gcgtgccagt tttaaagatt atttgactga aagtgagatt gccgatcgac
      121 tgttagctgc ttgtcccaac ttacgccaag gctatcagtt ataccaagac attctttatg
      181 cggtaaagaa aagagatcag tcactatttg aggattgttt aactagagac attagcggtc
      241 tgccagaaac ctatacaacc actttacgaa cgtttaaaaa gtttctgcca cagatccaaa
      301 atgcgcttca ctacagctat tcaaacggac cattggaatg cttaaacaac cacatcaaag
      361 tattaaaacg caatgcgtac ggctttcgca acttttacaa tttcaaacta cgaattatga
      421 ttcgtcatgg caaaacattt ttaaccaaat aaacag
//
LOCUS       DADQCX010000251          440 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.262, whole genome shotgun sequence.
ACCESSION   DADQCX010000251 DADQCX010000000
VERSION     DADQCX010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.262"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            11..>440
                     /locus_tag="J8R83_002904"
     CDS             11..>440
                     /locus_tag="J8R83_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9575965.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DADQCX010000252          423 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.263, whole genome shotgun sequence.
ACCESSION   DADQCX010000252 DADQCX010000000
VERSION     DADQCX010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.263"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>423
                     /locus_tag="J8R83_002905"
     CDS             <1..>423
                     /locus_tag="J8R83_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575966.1"
                     /translation="KDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSA
                     TKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGN
                     KKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          173 a           63 c           98 g           89 t
ORIGIN      
        1 gaaagacggc gtaagcttac cagaagataa acttccagtg ttgaaagcaa aagatggtta
       61 tacagatgcg aaatggccag aggaagcaac tcaaccaatt acagcagatg atacagaatt
      121 tgtatcaagt gcaacaaaac tggatgataa atctgacgct gacaaatata atcctgaagg
      181 tcaaaaagtg actacagaat tgaataagga accagacgca tttgagggaa ttaagaacaa
      241 agaagattta ccaaaagata ctaagtatac ttggaaagaa aaagtagatg ttagcgcagc
      301 tggaaataaa aaagggactg ttgtagtgac atatccagat ggatcatctg atgaagttga
      361 agtagatgtt acagtgacag acaatcgttc tgacgccgat aaatatgagc caacagtaga
      421 agg
//
LOCUS       DADQCX010000253          400 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.264, whole genome shotgun sequence.
ACCESSION   DADQCX010000253 DADQCX010000000
VERSION     DADQCX010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.264"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>400
                     /locus_tag="J8R83_002906"
     CDS             <1..>400
                     /locus_tag="J8R83_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9575967.1"
                     /translation="GMIFKFANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDGYLSKE
                     EVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTESDYDGNKITVSGTYDYEL
                     KIKTTTKNTGSYRTIELSSNAKEIIDQLIEE"
BASE COUNT          166 a           48 c           62 g          124 t
ORIGIN      
        1 ggaatgattt ttaaattcgc caaccgtcga tatggattaa aatataatcc cgtaaatggg
       61 gtttctttag caagaaaacc taagacaaac gaagaaataa aaaaagaaaa agatggttat
      121 ttatcaaaag aagaagttca aatgattgct agtaaacaaa aaagttcaca tcaacagtca
      181 cgttattctt taattactaa atttttgttt ttaactggac tacgttatgg tgaattgata
      241 tctttgactg aatctgatta tgatggtaat aaaattacgg tttctggtac ttatgattac
      301 gagttaaaaa ttaaaacaac aactaaaaat acaggttctt atagaaccat tgaattatca
      361 agtaatgcta aagaaatcat agatcaatta attgaagaaa
//
LOCUS       DADQCX010000254          396 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.265, whole genome shotgun sequence.
ACCESSION   DADQCX010000254 DADQCX010000000
VERSION     DADQCX010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.265"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..302)
                     /locus_tag="J8R83_002907"
     CDS             complement(<1..302)
                     /locus_tag="J8R83_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAZ9575968.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT          126 a           62 c           66 g          142 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttgtatagac tgattgtaac atggaacaaa ataaaaaggc
      361 aatacgcctt agttgtcggt cttcgagtta ccaacg
//
LOCUS       DADQCX010000255          381 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.266, whole genome shotgun sequence.
ACCESSION   DADQCX010000255 DADQCX010000000
VERSION     DADQCX010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.266"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>381
                     /locus_tag="J8R83_002908"
     CDS             <1..>381
                     /locus_tag="J8R83_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAZ9575969.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHK"
BASE COUNT          134 a           71 c           62 g          114 t
ORIGIN      
        1 actttcctag taggagtcga ttcactcgct taagttcaaa cttagcttac actatcaaga
       61 ttattcgata ctttttcatc aagaagctca ccaaaggtga actagtcgga attatagata
      121 gttttcctag tccattatgt aaaccagtta gaaatagaca agcaaaacta ttgaatcaaa
      181 tagccaaagt tggctataac tcaacaaaaa aatcttattt ttatggtctt aaaattcata
      241 tgatcgttac taagactggc tttccgatta cttactcaat cacgaatcca ggtgtccatg
      301 acgtgaaagt gttagagact ttatcggaag aagcgaatct tcccaatatc ctaggggaca
      361 aaggatatat tagccataaa a
//
LOCUS       DADQCX010000256          380 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.denovo.267, whole genome shotgun sequence.
ACCESSION   DADQCX010000256 DADQCX010000000
VERSION     DADQCX010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.denovo.267"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            25..207
                     /locus_tag="J8R83_002909"
     CDS             25..207
                     /locus_tag="J8R83_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAZ9575970.1"
                     /translation="MSVSTLGITVDAATYYGNGVYCNTQKCWVDWSRARSEIVDRGVK
                     AYVNGFTKVLGGVGGR"
     gene            197..>380
                     /locus_tag="J8R83_002910"
     CDS             197..>380
                     /locus_tag="J8R83_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9575971.1"
                     /translation="MEDKKEKLFDLIANAYNSKSYNNVEVKEGFLQDAKKIREDKPYP
                     EIIISVYKHLSKLKAEE"
BASE COUNT          139 a           37 c           80 g          124 t
ORIGIN      
        1 tttttgattt taggaattgt tttattgagt gtatctactt taggaattac agtagatgct
       61 gcaacttatt atggaaatgg tgtttattgt aatactcaaa aatgttgggt agattggagt
      121 agagctcgct ctgagattgt tgatagagga gtaaaagctt acgttaatgg ttttacaaaa
      181 gtgctaggtg gagtcggtgg aagataaaaa agaaaaactt tttgacttaa ttgcgaatgc
      241 atataattca aagtcatata ataatgtaga agtaaaagaa ggatttcttc aagatgctaa
      301 gaaaatacga gaggataaac catatcctga aattattata tcagtgtaca aacatttatc
      361 taaattaaaa gctgaggaac
//
LOCUS       DADQCX010000257        13213 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.076, whole genome shotgun sequence.
ACCESSION   DADQCX010000257 DADQCX010000000
VERSION     DADQCX010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.076"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(204..2162)
                     /locus_tag="J8R83_002911"
     CDS             complement(204..2162)
                     /locus_tag="J8R83_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9575972.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="J8R83_002912"
     CDS             complement(2159..3031)
                     /locus_tag="J8R83_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9575973.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="J8R83_002913"
     CDS             complement(3373..4245)
                     /locus_tag="J8R83_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9575974.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="J8R83_002914"
     CDS             4373..4942
                     /locus_tag="J8R83_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAZ9575975.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="J8R83_002915"
     CDS             5009..5746
                     /locus_tag="J8R83_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9575976.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="J8R83_002916"
     CDS             5977..7245
                     /locus_tag="J8R83_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAZ9575977.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="J8R83_002917"
     CDS             7732..8196
                     /locus_tag="J8R83_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9575978.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="J8R83_002918"
     CDS             8180..8809
                     /locus_tag="J8R83_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAZ9575979.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr"
                     /locus_tag="J8R83_002919"
     CDS             9163..10641
                     /gene="msr"
                     /locus_tag="J8R83_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAZ9575980.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="J8R83_002920"
     CDS             10688..11134
                     /locus_tag="J8R83_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAZ9575981.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="J8R83_002921"
     CDS             complement(11333..11848)
                     /locus_tag="J8R83_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9575982.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="J8R83_002922"
     CDS             11965..13167
                     /locus_tag="J8R83_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9575983.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DADQCX010000258         9750 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.097, whole genome shotgun sequence.
ACCESSION   DADQCX010000258 DADQCX010000000
VERSION     DADQCX010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.097"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            290..2176
                     /locus_tag="J8R83_002923"
     CDS             290..2176
                     /locus_tag="J8R83_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9575984.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2188..3135
                     /locus_tag="J8R83_002924"
     CDS             2188..3135
                     /locus_tag="J8R83_002924"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAZ9575985.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3155..3682
                     /locus_tag="J8R83_002925"
     CDS             3155..3682
                     /locus_tag="J8R83_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9575986.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3745..4398)
                     /locus_tag="J8R83_002926"
     CDS             complement(3745..4398)
                     /locus_tag="J8R83_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAZ9575987.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4530..5372
                     /locus_tag="J8R83_002927"
     CDS             4530..5372
                     /locus_tag="J8R83_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9575988.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5530..6426
                     /locus_tag="J8R83_002928"
     CDS             5530..6426
                     /locus_tag="J8R83_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9575989.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            6429..7142
                     /locus_tag="J8R83_002929"
     CDS             6429..7142
                     /locus_tag="J8R83_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAZ9575990.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            7162..7680
                     /gene="msrA"
                     /locus_tag="J8R83_002930"
     CDS             7162..7680
                     /gene="msrA"
                     /locus_tag="J8R83_002930"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9575991.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            7677..7904
                     /locus_tag="J8R83_002931"
     CDS             7677..7904
                     /locus_tag="J8R83_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAZ9575992.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            8056..8607
                     /gene="lepB"
                     /locus_tag="J8R83_002932"
     CDS             8056..8607
                     /gene="lepB"
                     /locus_tag="J8R83_002932"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9575993.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(8690..9232)
                     /locus_tag="J8R83_002933"
     CDS             complement(8690..9232)
                     /locus_tag="J8R83_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAZ9575994.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(9469..9723)
                     /locus_tag="J8R83_002934"
     CDS             complement(9469..9723)
                     /locus_tag="J8R83_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAZ9575995.1"
                     /translation="MLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQI
                     AKENGGTFHEVDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3508 a         1697 c         1919 g         2626 t
ORIGIN      
        1 gttttctgcg aacagctatc gcaggaatat caatttgtta gaatcttata cgatgaacaa
       61 accatctgat aacttttctt tccgatttgc gtttcgagca aagtcaaaaa aaacgagtcc
      121 aataaaataa aaaggtaaaa attttcaagt tttataaaaa acaaaacata tcagaacagg
      181 atcgaatcgg tcctgttctt tttttgagaa cacaaaaaga acaaatacca aaaaaatttt
      241 cctgaagttc actattttta tgatacaata tccaagataa ggagggaaca tgttgaaaga
      301 attaaaagta actgacctca aaaaaactta tggtgaaaaa gatttgtttg accagatttc
      361 ttttttggtc cacgaaaaag accgtatcgg gttgattggg acgaacggga cgggtaaaac
      421 aagtctctta aatattattg ccggtatcga tagcagcgac ggtgatcggc aaacagtgtt
      481 ttatccaact gattaccgta ttggttatct ttctcaagca gctgaatttt ccgatgaatt
      541 aactgttctc caagcagtct ttcaaggaaa cagccccttg atccaaactg ttcgagcata
      601 tgaggaagca ttgatcgaac taggggaaaa cggagaagac cctgatgtgc aaaaacgtta
      661 tgctaaagca gaagaacaaa tgaataaaga agatgcttgg actacagata ccaacgcaaa
      721 gattattttg caaaaattag gaatcagtga attagataaa aaaatcagta ctttatcagg
      781 tggtcagaaa aaacgagtta gtctggcgca agtgttgatt gatgaacccg atttactatt
      841 actagacgaa ccaacaaacc atttagatta tgaagcgatc gagtggttgg aaaactattt
      901 gaaacaatac cgtggcgcac tattgatggt tacccacgat cgttattttc tagatagagt
      961 agcaaaccga atcttcgaac tttcatttgg aaaattatac gagtataaag gaaattatga
     1021 agcttacgtc ttagaaaaag cagaacgtga tcgtgtagaa gtagaacaag aagaaaagcg
     1081 caagcggctt tataaacagg aattagcttg gatgagggct ggcgtacagg cacgtggcac
     1141 caagcagcaa gcacggatca accgtttcga agatctaaag gagaacttgt accaagtaaa
     1201 ccaagaagat gatttagagc tgaacctagc gacacaacgt ttagggaaaa aagtactgga
     1261 aatcaaagat ggcagttacc gtataaatga ccaaacactg ctagaacatt tagatttatt
     1321 gattcaatct cgggaaagac taggtattac tggtaaaaat ggtgcgggaa aatcgacatt
     1381 gcttaatatt ctagctggca gaattcccct ggatagcggt acaatgtcta tcggtgaaac
     1441 ggttcatctt gcgtattata cacaagaaaa tgaagaaatg gcaccagata aacggatgat
     1501 tgcttactta caagaagctg ctgaagaagc aaaaacagca gatggcagtc aaatcggagt
     1561 agcagaatta cttgaacgat ttttatttcc aagatttatg catgggacac tgataggcaa
     1621 actttcaggc ggagaaaaac gccggttatt tttgttgaaa ctgctgattc agcaacctaa
     1681 tgttttatta ttggatgaac cgaccaatga tttggacata gcaacattga cgattttgga
     1741 agattatttt agaagttttc caggtgctgt gatcactgtt tcccatgacc gttatttctt
     1801 ggacaaggta gcagataagt tattagtatt ccaaggaaac ggaaaacaag aactttatta
     1861 cggaaacatg tccagttatt tactgaagca aaaagagacc cagcagcctg ctgaaaaagc
     1921 gaaaccaaaa atacagagca aggaacctgc tgaaaagaag aaattatctt acatggaaca
     1981 aaaagaatgg gaaacgattg aagatgagat tgcagaactt gaagaaaaaa tctcattgct
     2041 ccaagaagag atgaatcatc aaggagataa tttcactcga ttacaagaat tgcaaaacga
     2101 cgtatctgaa acagaagcac aacttgaaga aaaaatggca cggtgggaat acttgagtga
     2161 atgggtagaa gattaggagg aaaaaggatg gaacaagcgt atcttgactt aggaagaaaa
     2221 ttgttggaag aagggcatcg taaagaagac agaacaggca caggcacatt aagcttattc
     2281 ggataccaaa tgcggtttga tctgcaaaaa gggtttcctt tgttaacaac gaaacgagta
     2341 ccttttggat tgatcaaaag cgaattgctt tggtttttaa aaggagatac gaatatccgc
     2401 tatctattac aaaataaaaa ccatatttgg gatgaatggg catttgaacg ctacatcaaa
     2461 agtccagact ataatggacc agatatgact gattttggcc atagatgttt gacagatcct
     2521 gaattcaatg aagaatataa aaagcagagc aagctttttt gcgagaagat cctaaccgat
     2581 gattcctttg ctgaaacata cggcgatctt ggacacatct acggctatca atggcgtcac
     2641 tgggaaacaa aagacggtgg ctttatcgat caaatcaaac aagtgatcga agcaatcaaa
     2701 aagactcctg attctagaag attgatcgtt tctgcatgga atccggaaga tgttcctagc
     2761 atggctttgc ctccttgtca tacgatgttt caattttatg ttcaagaggg acggctaagc
     2821 tgccaattgt atcaacgcag tggggatgtg tttctaggcg ttccgttcaa cattgcaagt
     2881 tatgcgttgc tgactcacct aattgcacat gaaacaggtt tagcggttgg cgaatttgtt
     2941 cacacattag gagatgctca tctttatatc aatcatatcg aacaaatgaa agaacaattg
     3001 agccgagaaa tacgcgcatt tccgacttta gttttgaatc aggaaaagca gtcagtattt
     3061 gattttgaga tggaagatat ccaattagaa ggatatgacc cacatccggc gatcaaagct
     3121 cctatcgctg tttagaatca gaaaggatga gaaaatgtta gctgcaattt gggcacagga
     3181 tgaaaacgga ttgattggaa aagaagaccg tcttccttgg cgtttgccaa atgatctgaa
     3241 attcttcaaa caaatgacag aagcaaatac actagtgatg ggacgaaaaa cattcgaagg
     3301 gatgggtagc cgtccgttgc cgaatcgtca gacgattgtt ttgacgagag attcttccta
     3361 taaagcagaa ggcgtgcatg tcatgcatag tgtggaagac gtgcttgctc tggaaaaaga
     3421 aacagacggt atctttttca tcgctggagg gtcagctgtt tatcaagaat ttctgccatt
     3481 ttgtacgata ttataccgta cagtcatcca tcatgtattc gatggagatg cttattttcc
     3541 acctgttgac tggtctgatt ggtcactgat caatactagt caaggagaaa tggatgaaaa
     3601 aaatcgttat ccgcatcaat ttgaaacgta tcagcgtaat gagaatcctg taaaaagcgg
     3661 gacaggcgaa ttgacgatat aaaaaagcta tggatagact agctgttatt tagagctgtc
     3721 ccatccatag ctttattttt tttattaagt aaagaataaa acagagaagt acataaaacc
     3781 tgcacctaac ataacaaaca aatgccaaac aacatgcata tagcggatag aattcaagct
     3841 ataaaagaat gcgcctatcg tgtaagaaag cccgcctgct accatcaaaa taacaccagt
     3901 cattccaaga gagtgataaa gaggaacagc agccacgaca cagagccacc ccataaaaat
     3961 atagatgatc gtagatactt ttgatactct ctcccgttta tgcaacgtca acgctttata
     4021 tataatgcca agaatcgcaa acaaccagat taatacaaat aaagtccaac ctagccatcc
     4081 tcggatactc agcaaacaaa aaggagtata acttcctgca atcaaaagaa aaatcgaact
     4141 atgatcgaat acttggaaca ccttttttgc ttttgtaaaa atcaatgaat gaaacaaagt
     4201 agacgttaaa aataaaagaa tcatcatcga tccatagata gcataagaga caatatggag
     4261 ggaggaatgc aagtgggcac cttttactaa aagaaccact agtcccgcga tactcaatcc
     4321 agtcccaatt ccatgggtga ctgcattaaa cacttcattt aatatttcat acgttcgatt
     4381 aaatttcgtt ttttccatga aaacggctcc tttactaggt gtaattaatg aaaaatcatt
     4441 atttgtctgt tatactaaaa atagaaattg tcttacatgt agtttaacat gaataaggca
     4501 tcttgttaaa gaaagagaga gagaaaataa tgacaaatgt aaaaatcgta acagattctt
     4561 catgtacgat ggaaaaaaat gtacgcgatg ctttaggcat tcgtgtcatg ccgctatcca
     4621 tcatgatcga cggaacagta tatcccgatg atgaccaact agacggcgaa agatttatgg
     4681 aaatgatggc gaaagcaaaa aatctgccca aaacaagcca accaccaatt ggagaattca
     4741 tctcgatgta tgatgagcta ggagaagacg gcagtgaagt gatttcgatc catatgacaa
     4801 aaggcttgag tggaacagta gaagcagcaa gacaagccag taatctaaca aaaacgaaag
     4861 taacggttat cgacagtgat accactgacc aaggattatc ttttcaggta attcgagcag
     4921 ctgaattagc aaaagaaggt aaaacagtag agaaaatcct tgaagaagtc aaaaaagtac
     4981 aagacaatac aaaattatac atcggaatat ccacactaga taacttggta aaaggtggaa
     5041 gaatcagccg aacaactggt ttgctgtcta gtgttttgaa catacgcgtg gtgatgaatt
     5101 tcgcccattc tgaattaatc cctgtaacta aggggcgagg aaagaaaacg ttcgataaat
     5161 ggtttaataa tttgaaaaat gaactgaaag aattgccaaa tgtgcgacaa atcggtattt
     5221 cacatgcgga tgcaaaagaa ttggcgcaag aattcaaaga gggtttgcaa gaattattcc
     5281 cggacatgca tatccctgta ctgcatacga atccggttat cgctacgcat actggtaaag
     5341 acgcgtttgc aatcatgtat tatgtagatt agtcgaaaag aggataagcc ctcagcctga
     5401 aaggcttgca gcttattctc tttttcttta taaaattagg aaaataattg ttttcttttt
     5461 tcataaagac tacctttttg ataaaatttt tgataacatt agaaccaatc gaatacaaga
     5521 ggtgaaaaaa tgaaattaac gaaacgacat ttgatcctcg ttttgttccc attattaatt
     5581 gcgatcatca tctatgcagg tttagctgct tctataccga aagctggccc actaatgaaa
     5641 ccagtaacta ctgtgagaga agatccaaat aaaaaagaaa aacttcacta catagctatc
     5701 ggagattcgc tgactgaagg agtaggagat caaaccaagc aaggaggatt cgttcccctt
     5761 gtcgcaaatg atctaaaaga ccgttataat ttgaccgcgg ttgaaacaga aaactatggt
     5821 gtaaatggtg aacgaagtga ccagatctta aagcgagtaa aaacaaaaga agaaattcga
     5881 aacaatatca aaacagctga ttttatcaca ctgactgttg gcggtaatga tttgatgaaa
     5941 gttatccaaa ataatttatt cgggttaacg gtcaattcct ttaaaaagcc actgaaaaac
     6001 tatcaggaaa atgtcacaga actattggaa gaatttcgat ccctcaataa aaccgcacct
     6061 atttacattt taggcatcta caatccattt tatttgaact ttcctgagat cactgacatg
     6121 cagacaattg ttaacaattg gaacaaagga acagaaacgg tgacaaaaaa aatgccgaac
     6181 tgctacttta tcccaatcaa tgatttgctt tatcaaggat tgaatcagga agtaggtgtc
     6241 acagaagaag gaacagatca aacaactagc acgacagaaa atctaaatgg catcaaaaat
     6301 aatgtgctct atgaagaaga tcatttccat ccaaataatt taggttatca attgatggca
     6361 aatgcagtga gagatcagct gatcgagaca caaaaccaat ggttagagaa ggaggatgat
     6421 caataaacat gaaaacaaga tctgacgtat cttcaaacaa aacaaagaaa acaaattact
     6481 ggaaattcgc cttccttatc cttcttgggg tagtacttgg ttcgaccgta tttttaggca
     6541 gccgtatttt tgctaatcgg gaaccagaac tcccagaaat accagctctt acggaaagac
     6601 aaggagatcc tgtcttaacg atcaattcaa ataaagaaaa agtcaatcaa atcatcagct
     6661 ttttccttag tgagtatcaa aaagatagtg atattgaata taaattttat ttggaaaatg
     6721 aagcactact caatggtact ttcgaagtac taggttttcc tatcgatttc tatttatatt
     6781 ttgatccgta tgtgatggaa aacggaaatg tccaactaaa agctagaagt ctttctatcg
     6841 gaacattgag tttgccaatc aaagatgtga tgaatatgat caagagaaac tataaattac
     6901 cagattggat cgaagtcaat acagatgatc tgactatcat gcttaggttg gatcaattcc
     6961 gaatgcaaaa cgggatgtat attaaagcag ataaaatcga cttagtaaat gatgacattc
     7021 ggtttagtct atatttgcca aaagatacct ctgatgcttc aaacaactca aataccaaca
     7081 aaactagcac cagcagtact gaaagcaaga caaaagaaaa taaaaaatca tcggatgagt
     7141 agtattagag ggggaatcat aatggaacga gcaatatttg caggaggctg cttctggtgt
     7201 atgatccagc ctttcgacac gcttcctggt atccatacag tgatgtcagg atatactgga
     7261 gggcatgtac cagatccgac ttatgaacaa gtaaaaagcc aaacgactgg acatacagaa
     7321 gcagtggaga ttatctatga tccaacattg atttcatatg aacaattagt agaactttac
     7381 tggcagcaaa ctgatccaac tgacgctttc ggacaattcg aggatcgcgg tgacaattat
     7441 cgcccggtga tcttttattt gacagaagaa cagcggatca ttgctgaaaa aagtaagaaa
     7501 cagttagctg aaagtggacg tttcgaacag ccaatcgtta caaaaatcga accagcccaa
     7561 ccattttatc tagcagaaga agaccatcaa gagtattata aaaagcatcc tgaaaatttt
     7621 aaaagaaacc atgcacgccg ggctgccttt atcgaagaaa attggaggaa cgaagggtga
     7681 atcgaagctt ttttcattat ttaatgacac tgcgaggcgg tggcacacat gatgctttat
     7741 ctgttttcgc tacagaagcc ggtaaagaca tccaatttcc taagcacagc tctagctacg
     7801 aagaaatttc taattatctg gaactgaatg tcgactattt gccgtccatg gatatctttg
     7861 acgaagcatg ggaaaaatat ttagaaaata atcatgacat ataagagata gttttgtact
     7921 ttatgatcaa aaaagttttt tgtccaatag cctaattgaa agaattattt ttatttcagc
     7981 tatctagtcg catttttttg atatttttct tataataaag aaagaatgaa aaaaagaggg
     8041 atggattgat agagattgac aaaaaaacaa cgctatatta atcgcttctg gcttgtattc
     8101 aaatacttac ttgtttctgt attccttgcg ttcatgttgc ggggattttt attcatcccg
     8161 gtaccagtgg aaggcaattc aatggaaaac gtgttgaagc aaggtgatat ggttgtgatg
     8221 gaaaaatttt cggagatcag acgatttgat attgttgttt ttcaattagc agatggcacg
     8281 atttatatca aacgagtaat cggtcttcca ggagaaaatg tcagctacca aaatgatcaa
     8341 ttgaagatca atgggaaagt agttaaggaa ccttatctaa ctaaaaacct gaaatcagat
     8401 catgcaaatg catcctatac gacggacttt acactacaag agctaacggg acaatccaag
     8461 cttccggaag ataattattt tgtacttgga gataatcgaa gagtttcaaa agatagtcgt
     8521 tcgtttggca cgatcaataa aactgatatt ctaggtaaag caagatttgt ctattatcca
     8581 cttgatgaaa taaaatggat ccagtgagaa acaataaagc gtgcagtctg ttgagactgc
     8641 acgctttatt gtttaatcca aaatcagttt actaccttag tacgtaaaat caaacagctc
     8701 gtttaaacac ttttctagcc tctaaagttt tgataaatga ataaacaacc attatttgaa
     8761 tagggatttg gatcatattc ctgatgaatc tacctagaaa aattactttg aaatctgcac
     8821 caaacaaaac agacatcagc caagaattga taaaaaggct gactgggatc ataatcaata
     8881 attgggcagc gatgacggaa ggcaggttta tctttttatg atataaaaat aagccattaa
     8941 taaatccacc aaggaaagcc gtgataagaa aagcagcttg aaacgttcct gaaccaaata
     9001 tcgtgaaatt taaagtgttc gacaacattt caagcaaacc agcccagatc ggtccatata
     9061 gataacccat aagcgccata cttaaaaatc cgaatgtgat ttgaaaataa gcaggaccaa
     9121 tcgctatctt gtataagatg acatcaaggg ctaataaaag agcagaggtc gacaacaatc
     9181 ttgcattcat ttcgggcaat ctaaaaacgt cttttgcaat caaagtgttc aaaatattct
     9241 ctcctttgtc agttaataat aaaaggatac cataaaatca ccaatgtgtc atgacacatt
     9301 ggtgatttac atacactggc atctaacaat taaaaaaagg gtgagaagac tgcttttata
     9361 aactgtaaaa aagagattgt acgaataaaa aaaatagagg cggagaatac ttatcgtatc
     9421 atccgccttt gtttttttgt tataaaaaac gtcagattag ttatctgctt acatcttcat
     9481 ccatacgggt tctaatgtat ttccgtctag atcttggact tctaatgaaa acatttcttc
     9541 ttcaggcatt cccatatcta cttcgtggaa agtaccacca ttttcttttg caatttgagc
     9601 aaattttttt acttcatccg cattttcaac actaaacgaa atcaaagcac cacttgtttt
     9661 tttattatca gctatttctt tatcttttat aaatttttta taaaaatcat gagagagaag
     9721 cattatccaa aaagtgtcat cccataccat
//
LOCUS       DADQCX010000259         7780 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.111, whole genome shotgun sequence.
ACCESSION   DADQCX010000259 DADQCX010000000
VERSION     DADQCX010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.111"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            245..1213
                     /locus_tag="J8R83_002935"
     CDS             245..1213
                     /locus_tag="J8R83_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAZ9575996.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="J8R83_002936"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="J8R83_002936"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAZ9575997.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="J8R83_002937"
     CDS             2243..2851
                     /locus_tag="J8R83_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAZ9575998.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3279..4190
                     /locus_tag="J8R83_002938"
     CDS             3279..4190
                     /locus_tag="J8R83_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAZ9575999.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4343..4828
                     /gene="vanZ"
                     /locus_tag="J8R83_002939"
     CDS             4343..4828
                     /gene="vanZ"
                     /locus_tag="J8R83_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAZ9576000.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5115..5444)
                     /locus_tag="J8R83_002940"
     CDS             complement(5115..5444)
                     /locus_tag="J8R83_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9576001.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5749..6078
                     /locus_tag="J8R83_002941"
     CDS             5749..6078
                     /locus_tag="J8R83_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9576002.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6068..6355
                     /locus_tag="J8R83_002942"
     CDS             6068..6355
                     /locus_tag="J8R83_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9576003.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPNLLCGTHENFYEQLKKIR"
     gene            complement(6634..7197)
                     /locus_tag="J8R83_002943"
     CDS             complement(6634..7197)
                     /locus_tag="J8R83_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9576004.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2567 a         1298 c         1546 g         2369 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
     3001 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
     3061 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
     3121 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
     3181 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
     3241 tcatacttcc aactatatag ttaaggagga gactgaaaat gaagaagttg ttttttttat
     3301 tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca ctgttttctc
     3361 aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta gaaaatagtg
     3421 ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat caaggaaatc
     3481 tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca gatatcgtga
     3541 atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt aatatttata
     3601 tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta aagggtggcg
     3661 ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt gtgctttacc
     3721 aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat tcaggtttat
     3781 cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga aagtggatag
     3841 aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa acagagttaa
     3901 caggaattca atatgaacca tggcatattc gctatgttgg tttaccacat agtgcgatta
     3961 tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa gaaaaaacca
     4021 tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt actaaaaata
     4081 ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat atagacggtg
     4141 taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa ggatggcgga
     4201 atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg gtaacgttag
     4261 ctttttaatt taaaacccac gttaactagg acattgctat actaatgata caacttaaac
     4321 aaaagaatta gaggaaatta tattgggaaa aatattatct agaggattgc tagctttata
     4381 tttagtgaca ctaatctggt tagtgttatt caaattacaa tacaatattt tatcagtatt
     4441 taattatcat caaagaagtc ttaacttgac tccatttact gctactggga atttcagaga
     4501 gatgatagat aatgttataa tctttattcc atttggcttg cttttgaatg tcaattttaa
     4561 agaaatcgga tttttaccta agtttgcttt tgtactggtt ttaagtctta cttttgaaat
     4621 aattcaattt atcttcgcta ttggagcgac agacataaca gatgtaatta caaatactgt
     4681 tggaggcttt cttggactga aattatatgg tttaagcaat aagcatatga atcaaaaaaa
     4741 attagacaga gttattattt ttgtaggtat acttttgctc gtattattgc tcgtttaccg
     4801 tacccattta agaataaatt acgtgtaaga tgtctaaatc aagcaatctg atctttcata
     4861 cacataaaga tattgaatga attggattag atggaaaacg ggatgtgggg aaactcgccc
     4921 gtaggtgtga agtgagggga aaaccggtga taaagtaaaa agcttaccta acactatagt
     4981 aacaaagaaa gcccaattat caattttagt gctgaggaat tggtctcttt aataaatttc
     5041 cttaacgttg taaatccgca ttttcctgac ggtaccccca aactaagatt tcatagatag
     5101 attttctgat aactttaaaa aacacgaata gcggaaagga tgtcttcatt cgctaaagag
     5161 taataaacta cttttccatc ttgacgtgat tttgccattc catgtttttt taaaaaacgt
     5221 aaatggtgtg acgttgtagc gacactagca gtaagtattt ctgctaaatc acagacgcac
     5281 atttccttat aggtttctaa agcatagaaa attttaattc tagaaaaatc gctgaaacat
     5341 ttccctaaca caagtaagtt tgaaaaatct ttttgatcca atttattttt tattccattt
     5401 actttttctt tatgtacgac agtcacttgg caaacttttt tcattcatct cacctcacat
     5461 tcaaacgatt atttgaatga agtataccta tttgatcact cttttgtcaa tctaccttaa
     5521 ttccaataca ctattataag caatttcatg tattgaagta aacttacttg caagtgcgtt
     5581 tttgattcca agttaaaaac atattattat tctacataat ttcctaatca aataaaactc
     5641 ctttgaaaat tgttctaaag gagttttatt attttgtatt tctactaaaa atagcgtaca
     5701 atgtaattac taagtaatta cgaaatgtaa aataatggag gaaataatat gattacaaaa
     5761 acaagaaaac aaggaaattc tattatgtta acggtcccta aagaattcga tgtgcccaat
     5821 ggtgttgaag tagaagctaa gcttgtagag aatggtatcc tttatgagtt tgtagagcct
     5881 aaaaaagaat tttttgattt tagtgaagat attttggctg atattctttc agaaggttat
     5941 agcaaacaag agatcttaaa agaatttaga aatagaaaaa atgcgttaac ttctgcattt
     6001 aaatctattg ctgaagatac tgttgcaaat tctaaaccga tgacaaaaga ggagttggca
     6061 gcagaaattg gcttatgaga ttctaccttc taaacacgta ataaagtatc taaaaaaatt
     6121 aaaagagaaa acattaaaag aacaattttt aacgataatt tatgatgaga tagcagttcg
     6181 tcctcattcg ggagaacaaa aaacgggtga tttatcagga atttgggcta ttggattcaa
     6241 gtatgcaggt acgacatatc gcgttgcata tgaaattaaa gataatgcag tgatacctaa
     6301 cttactatgt ggaacgcatg aaaattttta tgaacaatta aaaaagatta ggtaagaacc
     6361 caatgtttca acttgagagg atagacgaca ctttaaaaga taatttttaa cagctgagag
     6421 ttgtaatacc ctataatttt aaaccactaa cctatatatt tatgaaaaat agaaaaaatt
     6481 aaaacgcatt ttaagcctct ttcaaattaa aagcttcatc cttatgcaca aagagggctt
     6541 aaaatgcgtt attttatatt gttttttagt aataataaaa aaatcactct aattctccca
     6601 taaatattat agattcctaa agattaaaat agattattcc ctattgtctt ttaagtagcg
     6661 gtagagtgtt gccttgctaa taccagtcat ttccgtaatt tcttttacgc tataaacctg
     6721 acttttatac aattttactg ctcgatcaac atctttctgg ttcactcgtg gacggccacc
     6781 tttacgacct ctcgcacgtg cacttttcaa accttctttg gtacgttcaa caattaaatc
     6841 acgttcgaac tgactaaatg cttggaagac agtcatcatt aagcgtccgt gaggcgtgct
     6901 ggtatcgaag ttttctttca agctcaccag cttaacatgg tgttcttcaa aataggtaac
     6961 aaggtcaatc aaatcctttg tactacgacc caatcgagaa aaactttcta caattaccgt
     7021 atctcccgga cgaattttat cttttaaacg atttagttgg ggacgaaccg ctttggttcc
     7081 cgtcattttc tcagttagga tttcattaca attttgttca ttgagtaagt ctaattgacg
     7141 atttagttct tgtgaacgtg tactcactcg ggcataacca taaatgtatc cactcatgct
     7201 tttcttcctt tcgtacttta attctggctt gattgtatca taaaagggag ttatagatac
     7261 atagttaatg caacaagtta tgatacaaaa tatgacctct tttatttaat aaaagaggtc
     7321 atttcatttt gtctcataat cgattgtttt tgatacgagt gtgtatacga aataaacaaa
     7381 aaaatcttaa gtaaatttct agatacctaa tttaatccta actagtgtat cctaaagtta
     7441 ataacgagtt tatcacaatg aaaattataa aatgctccca tattagatat aacatgcaat
     7501 atttgaatta gaactacaaa atttattcgt tttataaagt aaataatgtt gagatactaa
     7561 ggaatagaat attataagga attgagctga atgtattgga taaaaaaaga ataactttat
     7621 tagagatgga ctataaaaat gctcgtaatt ttcttctgaa gtctgaaagc tatttgaatg
     7681 ctcagctacc agaatatatt agttttgacg aaactttaaa atctgctaaa aaagttttaa
     7741 cttcgccgtt tgtataatta agcgagacaa ataaaaaagc
//
LOCUS       DADQCX010000260         6446 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.123, whole genome shotgun sequence.
ACCESSION   DADQCX010000260 DADQCX010000000
VERSION     DADQCX010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.123"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            240..2687
                     /locus_tag="J8R83_002944"
     CDS             240..2687
                     /locus_tag="J8R83_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAZ9576005.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQPKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            2917..3984
                     /gene="rlmN"
                     /locus_tag="J8R83_002945"
     CDS             2917..3984
                     /gene="rlmN"
                     /locus_tag="J8R83_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAZ9576006.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(4177..5280)
                     /locus_tag="J8R83_002946"
     CDS             complement(4177..5280)
                     /locus_tag="J8R83_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9576007.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            5833..6381
                     /gene="aac(6')"
                     /locus_tag="J8R83_002947"
     CDS             5833..6381
                     /gene="aac(6')"
                     /locus_tag="J8R83_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAZ9576008.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2160 a         1104 c         1381 g         1801 t
ORIGIN      
        1 agttattact ggtaccaaaa actgattgaa gaaaatggag agaaccttta gttcacatac
       61 ttaaaacaag aaggtacggc tggatatggc cgtgcctttt cttgataaaa tcatttagaa
      121 attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa
      181 aactttagtt cccttacttt tttttgtata atgaaacttg atgaaatgag ggataataaa
      241 tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa
      301 aacagcagca ggaacaaatg ctgacgattg gtgttgggtt tgccttgatt ttatttgctg
      361 tcttcggctt tttaaaatta ggttttttag gaatattgat tgcaaacggc tttcggatca
      421 ttgcaggaaa tacttaccaa atcctctgtc ttttattagc cgtattagga ttttggattg
      481 tcattaagaa tacagagttt tcaattggta aaaaccgacg ctggtttggc ggcatactct
      541 tttatttcgg tatcttatta ttgttacatg cccatttatt tggcaaactc catactgggg
      601 aaccaaatat catggggacg acatgggatt tgttagccag tgatataaaa caaagtcaag
      661 tagacaataa cgttggtggt gggatgattg gagcaatcct ttatcatttt acttacttct
      721 tgattgcaca gcctggaagt tatttagcag cagtgctatt actggcagga ggagcattcc
      781 tgttcagtaa tctggaaggc tatcagctgt taaatggtat ccaatcaatt ggagaacgag
      841 tacaggaatt attggaaggt gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag
      901 agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg cttagctgca aaagaagctg
      961 cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
     1021 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
     1081 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
     1141 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
     1201 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
     1261 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
     1321 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
     1381 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
     1441 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
     1501 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
     1561 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
     1621 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
     1681 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
     1741 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
     1801 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
     1861 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
     1921 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaaccga
     1981 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
     2041 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
     2101 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
     2161 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
     2221 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
     2281 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
     2341 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
     2401 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
     2461 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
     2521 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
     2581 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
     2641 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
     2701 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
     2761 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
     2821 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
     2881 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
     2941 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
     3001 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
     3061 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
     3121 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
     3181 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
     3241 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
     3301 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
     3361 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
     3421 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
     3481 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
     3541 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
     3601 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
     3661 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
     3721 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
     3781 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
     3841 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
     3901 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
     3961 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
     4021 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
     4081 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
     4141 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
     4201 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
     4261 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
     4321 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
     4381 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
     4441 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
     4501 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
     4561 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
     4621 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
     4681 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
     4741 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
     4801 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
     4861 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
     4921 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
     4981 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
     5041 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
     5101 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
     5161 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
     5221 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
     5281 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
     5341 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
     5401 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
     5461 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
     5521 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
     5581 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
     5641 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
     5701 tttttttatt ttataagtaa gataaataat gaaagaatag agatactgat tggtagctaa
     5761 agatttttga gcgagaacat ttcgtttttt caaaaggact gttagaataa gcaagaacaa
     5821 gggggaagac gtatgataat cagtgaattt gaccgtaata atccagtatt gaaagatcag
     5881 ctttctgatt tactgagact gacttggccg gaagaatatg gagacagctc ggcagaagaa
     5941 gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag cggtagacca agatgagtta
     6001 gtaggattta ttggtgcaat ccctcaatac ggtatcacag gttgggaatt gcatccatta
     6061 gttgtagaaa gctcccgacg aaagaaccaa ataggtactc gattagtcaa ttacttagaa
     6121 aaagaagtag cttccagagg aggaatcacg atttatttag gtacggatga tttagaccat
     6181 ggaacaacgt taagtcaaac ggacctgtat gagcatacat ttgataaagt ggcttccatc
     6241 cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat taggttataa aatcgtaggt
     6301 gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa aacgattatt
     6361 cctcgaccaa attctcaata ataaaaagag gttgtgacag aagtaatcag cttcaagaaa
     6421 taagaaggaa tttacgaaaa ttactt
//
LOCUS       DADQCX010000261         5728 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.134, whole genome shotgun sequence.
ACCESSION   DADQCX010000261 DADQCX010000000
VERSION     DADQCX010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.134"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            94..990
                     /locus_tag="J8R83_002948"
     CDS             94..990
                     /locus_tag="J8R83_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAZ9576009.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1140..2081)
                     /locus_tag="J8R83_002949"
     CDS             complement(1140..2081)
                     /locus_tag="J8R83_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAZ9576010.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2207..3328
                     /locus_tag="J8R83_002950"
     CDS             2207..3328
                     /locus_tag="J8R83_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAZ9576011.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3586..5088
                     /locus_tag="J8R83_002951"
     CDS             3586..5088
                     /locus_tag="J8R83_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAZ9576012.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5155..5682
                     /locus_tag="J8R83_002952"
     CDS             5155..5682
                     /locus_tag="J8R83_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9576013.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         1875 a         1017 c         1211 g         1625 t
ORIGIN      
        1 ttttcataca aatataggaa acgttttact ggctttttac tatttaaaca ggctatcata
       61 ggaaaaagtg acagagaaag tgaggcggaa aagatgaaca aaaatgacgt actgctagtt
      121 gcaaaaaata aatcacttta ttttttgcct tccatccgct ctttagatgt ttggtccgga
      181 aaagatttac tacagtcgga attcattaaa tcagctagac aacagttggc aaattatcag
      241 ctgatcgttt ttttagatta tggatttgat atggagatgg ctcgacgcgt gcgcccattt
      301 accaatgcaa aaattgtgtt atttttttgg aatcacttca aagcagaaca cgaggcgatg
      361 ctgaagcagg cacaagatga accggcaatc gatgagattt atcattttga ttttttggaa
      421 gcaaaagaac ttgggctgaa acataatagt tcattttatt cgaaacatat gaatttttct
      481 tctagcgaac caaagacgga tctatttttt ggtgcaacga ataatgggag aaaagaacga
      541 gcagaaagct ataagcagga atttataaaa agagatgtta cgaccaacta tttcattctt
      601 ccacatcgag ggaatgaaca acctggatat cttacttatg aagagtacct gaaaaaaaca
      661 ggggaatcgc gcgggattct ggaactgttg cgggagggtc agcaaggagt gactttgcgg
      721 acatttgaat ccatgtattt tcaaaagaaa ctagtgacgg ataatcaagc gattgctcat
      781 tatcattttt atcgtcctga aaatattttt ttgcttcgag aacgtgattt agatgaatta
      841 ccggaatttc tgcatacacc atttaagcca atcctatcag agctattgga attttatgat
      901 gcagaaaatt gggcaaaacg atttatcact aacgattcca ctatttatga gcaatacgaa
      961 tatgacctct cctctgttga aaacaaataa aaaacctaca ttttgaagag attatgtact
     1021 gaaacaaaca agcacaattc ttatggcatc atgagagttg tgttttcttt ttgatctttt
     1081 attgggctta aaaaaagaga accagctgct gattcagctg attctcatca gagagccttt
     1141 tattctgcgc caaggattcc ttcttttgca tggactaatt gggtcaaaaa ggcacaatat
     1201 ggtgtagcaa tatcatattt ttgtcctttt cgccaaatgg caccattgat gtagtcgatt
     1261 tcagtcaaac gatggttttt gatcaggtct tggtacatag atgggtaatg caacccgatg
     1321 ttgtcaggat cataagtaga agcaatatgt tggtacactt cttcttgatc tagtatgatt
     1381 ccttcttttg ctgcgataga agcaaattca gatacgattg ttcgaaccat gctctctgcc
     1441 gctttttgcg cgcctagttc agcaatatta caatccaaaa tcgtgcataa accattcaat
     1501 gttccattta cacaagcttt tcgccaaatg gaataacgaa cgttatggct atagatcgga
     1561 tttaaatttg cttcttgaaa gacttctaca actttttttg taaatgcttc gccttctggt
     1621 tccaagttct ctagttcgat ttctccatca cctaacaatg tgacttttcc gggaccagct
     1681 agaccagctg tccacatcgt gatcccaaat aagatatttt tctttggcac atatttttcc
     1741 agtacatctt catgacctaa tccatttagt aaacacaaaa cataagtatt gtcagtaata
     1801 atggattgga tcgaacaaaa catatcatct aattgattgg cttttgttaa tgctacgatc
     1861 aagtccacgt gttcgttgct ttcgatgatt tcttctggtg aatagattgg cagttttgcg
     1921 accacttctt taccgttaaa gtcagcaatc aacccatttg tacgaatggc ttcaatgtga
     1981 gcaggccaac gatcgatcaa gaggacctca tttccgcttt gatgtagcat caatccgatt
     2041 cggctgccca ttgctccggc cccagctatt gcgattttca tgttttttct ctcctttatt
     2101 caatgagttc ccttttagta tatagaaaaa tggaagaaaa tagcattgtt ttgtttgaaa
     2161 aaaatgaaaa aaagtgtctt acttaagaag aaagtgaggg atacagatgg atattttggc
     2221 ggcaattgat tcatttaaag gaagtgcttc ttcatttgaa ctaaatcagg cagttctaaa
     2281 tggctgggaa gatcgtaaag gaagaaaaat caatgtgccg attgcagatg gcggagaaaa
     2341 tactgcagaa gcaatctatt acgcgctcag gggaacatgg cgtaccattg atgggatgga
     2401 tctcttattc cgtcagcgaa aaatcagcta tttattgaca acttggcaag gaaaaaacac
     2461 cgcagtcatc gaatctgcac aagcattggg gttagatcta cttgataaac caacggatca
     2521 aactatccga cttgcttcca gttatgcctt aggagaactt attaaagatg cactgcttca
     2581 agaagtagaa caaattattg tcactttagg aggaagcggg tgtagcgatg gtggtctagg
     2641 attactccaa tccttgggtg cttctttaga agggtacaca gaaggaaatc ctttattatc
     2701 tactaaaaaa cttcattttg atcgaagaaa cgttcttgtt tctaaagtaa aattgattat
     2761 cgctgcagat gttaccaatc catatacagg tcaacaagga gctgcttggc aatttggaag
     2821 acaaaaagga ggaatagata cgacgctagc tttcttagat aaacaagcag gaaagattgc
     2881 tcagcaaata aaagatttct gggaggtgga tttagatgat attccaggaa gtggagcagc
     2941 aggcggtatt ggtggagccc tttttttgtt gggagcgaag atggtttctg gtttcgattt
     3001 agtcagccaa atcactggat tggaaaaaaa gatcgaacaa gcagatgtca tcattacagg
     3061 agaagggcgg atcgatcagc aaacgatcca cggaaaagtt ccatacggtg tagcagtgct
     3121 tgcaaaaaaa tatcgaaaac caataatcgc tatttgcgga agtagagacc aagagctaga
     3181 aggactttct gattttctcc caattgtctt aagtattcat ttgggtccaa taggtttaga
     3241 agaagcaatg gaacacaggc aaacattaga aaaaacaaaa atcttaggac agacacttag
     3301 cagatttttc accatcctcc cgaagtagtt gacaaaatca ttttctttat gctatcgtaa
     3361 tttcaaatat aggacaaagt gagggatccg tgcattgaaa aattaagtcg attgatgaaa
     3421 gctgcattca gactgtacct tgtggagaca aggaagcagt gtgcagattt tcgggattgg
     3481 cttggttttt tcgatgtatg ggtctttttg tgtgtatcca acccttgcat cctctttagc
     3541 cagttctgaa aataggactg gtcttttttt acgaggtgat ggaaaatgtc taaaatcgaa
     3601 ataaaaaatc tgacattcgg ctacgacagc caaggcacat tattatttga acaagcaaat
     3661 ctaaattttg acacacaatg gaaactagga cttatcggac gaaacggtcg aggaaagaca
     3721 actttactga atattctaca aaacaaacta ccttatcaag ggcaagtaat ccatcagcaa
     3781 gaatttgcct atttcccgca acagacaaaa gataaagaac gtttaaccta ttacgtgtta
     3841 aatgatatta cggattttga gatatgggaa atcgaaagag agctccaatt gatgcaaaca
     3901 gatcctgaaa tcttatggag agaattcagc acactatcgg ggggagagaa gacaaaagtc
     3961 ctactggcac ttttatttgt ggatgacact catttcccgt taatcgatga accaacgaat
     4021 catttggata tctctggtag aaaacaagta gcggcttatt tgaaaaagaa aaaacaaggc
     4081 ttcatcgtgg tcagccatga ccggggattt atcgatgaag tagtggacca tgttttagca
     4141 atcgaaaaaa gtcaactgga actttatcaa gggaatttct ctatctatga agaacagaaa
     4201 aaacttcgtg atgaatttga aatggctcaa aatgaaaaat tgaaaaaaga agtcagtagg
     4261 ctaaagaaaa cagcagctga aaaagccgaa tggtctcgtt cccgagaagg agataaaaca
     4321 aagaaacaag tcggattcat cgatactgaa tctagacgag tgaataaagg agcagtgggt
     4381 gctgatgctg cacggacgat gaaacgatcc aaagcaatcg tgaatcggat ggagacccag
     4441 atcagcgaga aagaaaaact attaaaagat atcgaatata tcgattcttt gacgatgaat
     4501 agccaagcgt ctcaccataa gcgactttta agcgtagaag atcttcaatt agggtatgaa
     4561 aatctgttat tcgagccaat tcattttaca atcgagcctc atcagcgggt ggcgatttca
     4621 ggtcctaacg gtgcaggaaa gtcatccatt atccattatc ttctgggggc attcaacggc
     4681 aaggttatag gagaaaaata ccagccaaaa catctgagca ttagttatgc aagccaaaat
     4741 tatgaagaca atcgaggaac gttggcggaa tttgcagaga aaaaccaagt agactaccaa
     4801 gcatttttga acaacctccg aaagcttggg atggaaagag atgtttttca taacaagatc
     4861 gagcagatga gtatgggcca acggaaaaaa gtggaattgg ctaaatcttt atcacagcca
     4921 gctgaactat atacatggga tgaaccattg aattatttgg atgtcttcaa tcaagaacaa
     4981 ttagaacaac tgatcttgaa cgtgaaacct gccatgttac tagtggaaca tgatcaaacc
     5041 ttcctggata aagtatctac tgagattatt tctcttgaga gaatctaacc cttgtaatct
     5101 caagaacaac aaggtatggt taaggggaac tttgccaacg aaggagagaa tcacatgctt
     5161 tatgtaacga gacacggaga aacaacttgg aacgcacaag gattagtttg cggacgggca
     5221 gatgtgccgc tgactgaaaa aggacagatg caggcacaga aactagcaga aaaggtagta
     5281 gatttgcctg ttccaatcac gaaaatcatc cattcccctc ttcaacgagc aagagataca
     5341 gcacaagcag ttgctgatcg tctcagcttg ccgctgaccg ttgatgaacg attggtagaa
     5401 atggattttg gggattatga tggactgcca agcaaagatg agaactttca aaaagcacgt
     5461 ttagcgttcg ctgtacgatt cccaaatggg gagtcagtct tagatgtgta tgcacggatc
     5521 gttcctttat tgaaagaatg catcgaagac gaagaaaatg tctatctgtt agtttgccat
     5581 aatgccttga taagagtgat caatgcttat tttcatccga tgcctaatga ggggttcttt
     5641 acattcatgg tagataatac agaattggtt tcttatgagt aattatgttt ttgtgttatt
     5701 taaataaaat atttcaaggc actgcttt
//
LOCUS       DADQCX010000262         4314 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.155, whole genome shotgun sequence.
ACCESSION   DADQCX010000262 DADQCX010000000
VERSION     DADQCX010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.155"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..400
                     /locus_tag="J8R83_002953"
     CDS             <1..400
                     /locus_tag="J8R83_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAZ9576014.1"
                     /translation="YLIVDLKLCNRTNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFR
                     IVSCLNQVLFACNNAYCINEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDM
                     TEKLYNEVNEIVSEINNFLNEESSDERKQI"
     gene            381..1115
                     /locus_tag="J8R83_002954"
     CDS             381..1115
                     /locus_tag="J8R83_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9576015.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1148..2056
                     /locus_tag="J8R83_002955"
     CDS             1148..2056
                     /locus_tag="J8R83_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAZ9576016.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2053..2595
                     /gene="sat4"
                     /locus_tag="J8R83_002956"
     CDS             2053..2595
                     /gene="sat4"
                     /locus_tag="J8R83_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAZ9576017.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            2688..3482
                     /locus_tag="J8R83_002957"
                     /note="aph(3')-IIIa"
     CDS             2688..3482
                     /locus_tag="J8R83_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAZ9576018.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(3590..3778)
                     /locus_tag="J8R83_002958"
                     /pseudo
     CDS             complement(3590..3778)
                     /locus_tag="J8R83_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3758..4300
                     /locus_tag="J8R83_002959"
     CDS             3758..4300
                     /locus_tag="J8R83_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9576019.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPVLLQSFK"
BASE COUNT         1478 a          648 c          980 g         1208 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaac ttttttatgt ttgaagcagg
       61 gttctcttta atgtttgtaa aagcaaattc gggaacagac gataaatatt atattgcggg
      121 tcatgttttt cgtatagttt catgtttaaa tcaagtgtta tttgcatgta ataatgctta
      181 ttgtatcaac gaaaagaaag ctataaaact gcttgaaact tttgaacata aacctgaaaa
      241 atataccgag aaggtaaatc atatttttga agtactcggt atctcacttt ttgaatgcta
      301 cgacatgacc gagaagcttt ataatgaagt gaatgaaatt gtatcggaga taaataactt
      361 tttaaacgag gagagttcag atgaaagaaa acaaatatga tgataatata ttttttcaaa
      421 aatacagtca aatgagtcgc tcgcagaaag gactggctgg tgcgggagaa tgggagactt
      481 tgaaaaagat gctacctgat tttaagggta agcgtgtgct tgatttagga tgcggctatg
      541 gatggcactg tatatatgcg atggaaaacg gtgcttcctc tgtagtaggt gttgatattt
      601 ctcataaaat gctcgaagta gcaaaaggaa aaacccattt tccacagatt gaatatgaat
      661 gctgtgccat agaagatgtg gatttcccag aggagagctt tgatgtaata ctaagttcgc
      721 ttgcgtttca ttatgtagca gactatgaga atttaataaa aaagatatat aggatgctga
      781 aggctggtgg caatttagtt tttacagttg aacatcctgt ttttactgct catggaacac
      841 aagactggta ttataacgaa aaaggagaaa tactgcattt cccggtggac aattattatt
      901 atgagggcaa acggacagct atgtttttgg aagaaaaggt tacaaaatat catagaacac
      961 tgaccacata tctaaataca ctgctttcaa atagttttat aataaatcag attgtggagc
     1021 cacagccgcc agagaacatg atggatattc cggggatggc ggatgaaatg cgacgcccaa
     1081 tgatgctgat tgtatcggca aaaaagaaga tgtaataata tagaaaaaat aaacgaggag
     1141 tatgtaaatg agatcagaaa aagaaatgat ggatttagta ctttctttag cagaacagga
     1201 tgaacgtatt cgaattgtga cccttgaggg gtcacgcgca aatattaata tacctaaaga
     1261 tgaatttcag gattatgata ttacatattt tgtaagtgat atagaaccgt ttatatctaa
     1321 tgatgactgg cttaatcaat ttgggaatat aataatgatg caaaagccgg aggatatgga
     1381 attattccca cctgaagaaa agggattttc ctatcttatg ctatttgatg attacaataa
     1441 aattgatctt accttattgc ccttggaaga gttagataat tacctaaagg gcgataaatt
     1501 aataaaggtt ctaattgata aagattgtag aattaaaagg gacatagttc cgactgatat
     1561 agattatcat gtaagaaagc caagcgcaag ggagtatgat gattgctgca atgaattttg
     1621 gaatgtaaca ccttatgtta ttaaaggatt gtgccgtaag gaaattttat ttgctattga
     1681 tcattttaat cagattgttc gccatgagct gctgagaatg atatcatgga aggtcggcat
     1741 cgaaacaggc tttaaattaa gtgtaggcaa gaactataag tttattgaaa ggtatatatc
     1801 cgaggatttg tgggagaaac ttttgtccac ctaccggatg gattcctatg aaaacatatg
     1861 ggaagcatta tttctatgcc atcaattgtt cagggcggta tccggtgagg tggcggaaag
     1921 gcttcattat gcctatccgg agtatgatag gaatataaca aaatatacca gggacatgta
     1981 taaaaaatac actggtaaaa ccggctgcct ggatagcaca tatgccgctg atatagaaga
     2041 gaggcgggaa cagtgattac agaaatgaaa gcagggcacc tgaaagatat cgataaaccc
     2101 agcgaaccat ttgaggtgat aggtaagatt ataccgaggt atgaaaacga gaattggacc
     2161 tttacagaat tactctatga agcgccatat ttaaaaagct accaagacga agaggatgaa
     2221 gaggatgagg aggcagattg ccttgaatat attgacaata ctgataagat aatatatctt
     2281 tactaccaag acgataaatg cgtcggaaaa gttaaactgc gaaaaaattg gaaccggtac
     2341 gcttatatag aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat aggcagcgcg
     2401 cttatcaata tatctataga atgggcaaag cataaaaact tgcatggact aatgcttgaa
     2461 acccaggaca ataaccttat agcttgtaaa ttctatcata attgtggttt caaaatcggc
     2521 tccgtcgata ctatgttata cgccaacttt gaaaacaact ttgaaaaagc tgttttctgg
     2581 tatttaaggt tttagaatgc aaggaacagt gaattggagt tcgtcttgtt ataattagct
     2641 tcttggggta tctttaaata ctgtagaaaa gaggaaggaa ataataaatg gctaaaatga
     2701 gaatatcacc ggaattgaaa aaactgatcg aaaaataccg ctgcgtaaaa gatacggaag
     2761 gaatgtctcc tgctaaggta tataagctgg tgggagaaaa tgaaaaccta tatttaaaaa
     2821 tgacggacag ccggtataaa gggaccacct atgatgtgga acgggaaaag gacatgatgc
     2881 tatggctgga aggaaagctg cctgttccaa aggtcctgca ctttgaacgg catgatggct
     2941 ggagcaatct gctcatgagt gaggccgatg gcgtcctttg ctcggaagag tatgaagatg
     3001 aacaaagccc tgaaaagatt atcgagctgt atgcggagtg catcaggctc tttcactcca
     3061 tcgacatatc ggattgtccc tatacgaata gcttagacag ccgattagcc gaattggatt
     3121 acttactgaa taacgatctg gccgatgtgg attgcgaaaa ctgggaagaa gacactccat
     3181 ttaaagatcc gcgcgagctg tatgattttt taaagacgga aaagcccgaa gaggaacttg
     3241 tcttttccca cggcgacctg ggagacagca acatctttgt gaaagatggc aaagtaagtg
     3301 gctttattga tcttgggaga agcggcaggg cggacaagtg gtatgacatt gccttctgcg
     3361 tccggtcgat cagggaggat atcggggaag aacagtatgt cgagctattt tttgacttac
     3421 tggggatcaa gcctgattgg gagaaaataa aatattatat tttactggat gaattgtttt
     3481 agtacctaga tttagatgtc taaaaagctt taactacaag ctttttagac atctaatctt
     3541 ttctgaagta catccgcaac tgtccatact ctgatgtttt atatcttttc taaaagttcg
     3601 ctagatagag ttctatatta gagatgtaaa gagttttggt gaagaggttt gtgagtatgg
     3661 cttttataac cagggtgcaa tgagaagcac taacagcagc tagcttaaga acgcatagga
     3721 tatacttttt atggaagtca cagaggagga ataaaatttg aacaggatta acagagtaac
     3781 ctctattctt attcagctgc aatcaaaaaa aataattcct gccaaagaaa ttgcacagcg
     3841 atttaatata agcttaagga cagtttacag agatatccgg acacttgaag aagccggaat
     3901 accaattgga tctgaggccg gaaaaggata ttttcttgta gagggcttcc tacttccgcc
     3961 ggtaatgttt acagcggcgg aagtgggtgc attgattaca gcagggaaat ttttaaattg
     4021 ccatggagat gaatcattta taaaggattt tgattcagct atgtataaaa tcaaatctat
     4081 tttgaagcat ggtgaaaaaa actatgcaca ggagttggag aacagtatta acgtgtacag
     4141 cacatctgga cagaaaaata cattggcgga taacgttatt gcagcaattc agactgcaat
     4201 ctgcaataaa agggtaatat caattcaata tcctgcatca ggagggcaag aaccggaaag
     4261 cagaatgata gagccggttc tgttgcaaag ttttaaataa agaataaaat ccct
//
LOCUS       DADQCX010000263         3720 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.166, whole genome shotgun sequence.
ACCESSION   DADQCX010000263 DADQCX010000000
VERSION     DADQCX010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.166"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            554..640
                     /locus_tag="J8R83_002960"
                     /pseudo
     CDS             554..640
                     /locus_tag="J8R83_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance protein"
     gene            641..2581
                     /gene="tet(S)"
                     /locus_tag="J8R83_002961"
     CDS             641..2581
                     /gene="tet(S)"
                     /locus_tag="J8R83_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HAZ9576020.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            2669..2836
                     /locus_tag="J8R83_002962"
     CDS             2669..2836
                     /locus_tag="J8R83_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9576021.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(3350..3706)
                     /locus_tag="J8R83_002963"
     CDS             complement(3350..3706)
                     /locus_tag="J8R83_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009009558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9576022.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
BASE COUNT         1327 a          577 c          618 g         1198 t
ORIGIN      
        1 tatttgatag tagatttaaa actttgcaac agaacccttt taatgatatt ttccaagtca
       61 aacttaatat taacaattca aaactattgg aaccactgca aaatattttg ttaagcagta
      121 tatatttcaa aaattatacg taatatattt gtagaaaggt tgtggacagt tgtcctattg
      181 acctgaaaag taatataata gctggatgaa taaagaatcc cttatgaact tgtaaatcgt
      241 tattaaatcg ctgaattttg atagccattc tgaagagtta tcttcaacta ctacactaac
      301 ttccattaat ttctcattaa tttccctttc gttcaaaaaa tatggttggc tttacaagca
      361 ttctatcata tgatagaatt aagataacat tcaaaaggag ataataaaaa tgcggcaagg
      421 tattcttaaa taaactgtca attagatagc gggaataatt aattaagcat ccttatttaa
      481 aataaggact ggttttttgt gcccagttta agaatacttt tatcatttta tcataaagca
      541 tctgtggcta tcagtgtgta gtatacagct atttttgtat taaaatccca gtgataagag
      601 tatttatcac tgggattttt tctgcttttt gagcttttga atggaggaaa taaaattgaa
      661 aattattaat atcggtatct tagcacatgt tgatgcagga aaaactactt tgacagaaag
      721 cttactatac agtagcggag caattaaaga gttaggaagt gtagatagcg gtacaacgaa
      781 aacggatact atgtttttgg aacgccagag aggtattact attcagaccg caataacatc
      841 ttttcaacgg gaaaatgtta aagtaaatat tgtagatact cctggacaca tggatttttt
      901 ggcagatgta taccgttcat tatctgtttt ggatggagct attttgctaa tctctgcaaa
      961 agatggagta cagtcacaaa ctcgtatact attccatgca cttagaaaga tgaacatacc
     1021 tataatattt tttattaaca aaattgatca aaatggaata aatttgccag atgtttatca
     1081 agatattaag gacaaacttt ctgacgacat cataattaag cagactgtga atctaaattt
     1141 gaaaccttat gtaatagatt atactgaacc agaacaatgg gagacagtaa ttgtgggaaa
     1201 tgattattta ttagaaaaat ataccattgg gaaaacattg aatattgcag aacttgaaaa
     1261 ggaggaaaac gaaagaattc aaagttgctc cttatatcct gtttatcacg gaagtgcaaa
     1321 gaataatatt ggaattaaac aacttataga ggtaattact agcaaattat tttcacccac
     1381 acaactcaat tcagataaac tttgtggaaa tgtttttaaa gtagaatatt cagatgatgg
     1441 tcaacggctt gtctatgtac gtctttatag tggaacgcta catttgcgag actcagtcaa
     1501 tatatcagaa aaggaaaaaa taaaagttac agaaatgtat acttcaataa atggagaatt
     1561 acgccagata gataaggcag agcctggtga gattattatt ttaaaaaatg agcttttaaa
     1621 actaaataac gtacttggag ataaaaaaag attaccacat agagaaattc ttgagaatcc
     1681 tcttcctatg ttacaaacaa caattgaacc atgtaaatca gtacaaagag aaaagttact
     1741 agatgcactt tttgaaatat ccgatagtga tccccttcta caatattatg tagatacagt
     1801 aactcacgaa attgtgctat cttttttagg tgaggtccaa atggaggtaa cttgtactct
     1861 gattcaagaa aaatatcata ttgagataga aacaagaaaa ccaactgtca tttatatgga
     1921 aagaccatta aaaaaatctg aatttaccat tgatatcgaa gtacctccaa atcctttctg
     1981 ggcttctatt ggtttatctg taacaccact tcctttgggt agtggcattc agtatgagag
     2041 cctggtttct ctaggttatt taaatcaatc atttcaaaat gcagttatgg aaggtatacg
     2101 ctatgggtgt gaacaaggat tgtacggttg gaaattaaca gactgtaaga tctgttttaa
     2161 gtatggtcta tattacagcc ctgtcagtac gccagcagat ttccgaatgc ttgcgcctat
     2221 tgtactagag caggctttta gaaagagtgg tacagagtta ttagagccat atcttagctt
     2281 cgaaatttat gtaccacaag aatatctttc gagagcatat aatgatgctt ccaaatattg
     2341 tgcaaatatt ttaaatacta agttaaaagg taacgaggtc attctcattg gtgaaattcc
     2401 agcccgttgt attcaagagt atcgaaacag tttaactttc tttacaaatg gacgcagtgt
     2461 ctgtttaaca gagttaaaag gttatcaggt tactaacatt aagtctgctt tccaaccacg
     2521 tcgtccaaat aatagaatag acaaagtaag gcatatgttt aataaaatca acttacattg
     2581 atagtgaact aaagagaaat ttttaaaatg aatattgagt tgttaattag aacaggagga
     2641 tatagatatt gtaaatacta ggtggatact gtgccctata tgtggcaata agacccgttt
     2701 aaaaatgagg gaagatactg aattaaaaaa tttccctcta ttttgtccta aatgcagaca
     2761 agaaatttta attgaaataa cgaagtttag aataactgta attacagagc cagacgcaaa
     2821 gacgcagagc cgataattcg agatatcaaa atctcatttt atcggctttt tcttttctat
     2881 gcataccatt gagcttagtt cttgatatcc tttataagaa aataagtgta ctgatttttt
     2941 ttgcagtagc tgtattacag tagacatccc tcaagcataa aaagtataca attaaaattc
     3001 aatacttgat tattgatgaa gtacagagtt actcgtcatt tcaaaactag tatatcagtc
     3061 aagtttttcc taaggaacaa aaacgaactt cgctatggga atcaaaaatt tttagtcgga
     3121 tgaagtgata tgcaataaat ccagaaaatt ttcccaacaa caaaaaatga actgtacttt
     3181 gcagcgataa gagtaaccaa agaactattt atcattcgct ctagttccta agtgtaacaa
     3241 agataaattc attttctatt tatgattaac aaaaatcaga aaaaattcat tacatctttg
     3301 taatcaatct ttcctgatag tattaattaa tccattgtgt attattgaac tagttaaatt
     3361 tacatttttc tccgtaaatt gcttgaatca ctttcccaat cgtcactaat tcatcttcat
     3421 ccagacaatc caactgtgct tctacttgaa gacgtttgga gcttttatga ctgttttctt
     3481 cccctaaaat aaatccatcc aaagaaatat ttagcaaagt cactaaatca tatacaacat
     3541 gaaaacttgg ctgttgtcct ttattttcaa tgttcgtcaa atagcgtggc gcaatctgga
     3601 tcattgatcc tacctgctca cgagtcaatc ctttactaag acgggcttct ttaatcgcaa
     3661 gacccaatgg tttgaaatca aaatttgata gagtagtttg ccatattctt gcacccaacg
//
LOCUS       DADQCX010000264         2553 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.182, whole genome shotgun sequence.
ACCESSION   DADQCX010000264 DADQCX010000000
VERSION     DADQCX010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.182"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..459
                     /locus_tag="J8R83_002964"
     CDS             <1..459
                     /locus_tag="J8R83_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9576023.1"
                     /translation="TLFDSRFKTLQQNLQEDDIIYVTDLTRITRSTQDLFELIDNIRD
                     KKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFK
                     GRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            673..1368
                     /gene="vanR"
                     /locus_tag="J8R83_002965"
     CDS             673..1368
                     /gene="vanR"
                     /locus_tag="J8R83_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAZ9576024.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1346..2500
                     /locus_tag="J8R83_002966"
     CDS             1346..2500
                     /locus_tag="J8R83_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAZ9576025.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          880 a          454 c          535 g          684 t
ORIGIN      
        1 accttatttg atagtagatt taaaactttg caacagaacc tacaggaaga tgacatcatt
       61 tatgttacag acttaactcg aatcactcgt agtacacaag atctatttga attaatcgat
      121 aacatacgag ataaaaaggc aagtttaaaa tcactaaaag atacatggct tgatttatca
      181 gaagataatc catacagcca attcttaatt actgtaatgg ctggtgttaa ccaattagag
      241 cgagatctta ttcggatgag acaacgtgaa gggattgaat tggctaagaa agaaggaaag
      301 tttaaaggtc gattaaagaa gtatcataaa aatcacgcag gaatgaatta tgcggtaaag
      361 ctatataaag aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg
      421 gcttcattat acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg
      481 ggcaatattt ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc
      541 gaaaagccct ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg
      601 taaatgctta taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa
      661 agggtgataa ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat
      721 ttggttgaat tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa
      781 gaagcattgg aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt
      841 cccggcacaa gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt
      901 atcatgctga ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg
      961 gatgattata taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag
     1021 ttgcgccgat acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac
     1081 tccggccttg tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc
     1141 cttactccca ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt
     1201 agctccgagc tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac
     1261 accatcaccg tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg
     1321 aaatatataa aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta
     1381 ttccaaacta gaacgaaaac tttacatgta tatcgttgca attgttgtgg tagcaattgt
     1441 attcgtgttg tatattcgtt caatgatccg agggaaactt ggggattgga tcttaagtat
     1501 tttggaaaac aaatatgact taaatcacct ggacgcgatg aaattatatc aatattccat
     1561 acggaacaat atagatatct ttatttatgt ggcgattgtc attagtattc ttattctatg
     1621 tcgcgtcatg ctttcaaaat tcgcaaaata ctttgacgag ataaataccg gcattgatgt
     1681 acttattcag aacgaagata aacaaattga gctttctgcg gaaatggatg ttatggaaca
     1741 aaagctcaac acattaaaac ggactctgga aaagcgagag caggatgcaa agctggccga
     1801 acaaagaaaa aatgacgttg ttatgtactt ggcgcacgat attaaaacgc cccttacatc
     1861 cattatcggt tatttgagcc tgcttgacga ggctccagac atgccggtag atcaaaaggc
     1921 aaagtatgtg catatcacgt tggacaaagc gtatcgactc gaacagctaa tcgacgagtt
     1981 ttttgagatt acacggtata acctacaaac gataacgcta acaaaaacgc acatagacct
     2041 atactatatg ctggtgcaga tgaccgatga attttatcct cagctttccg cacatggaaa
     2101 acaggcggtt attcacgccc ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc
     2161 gagagtcttt aacaacattt tgaaaaacgc cgctgcatac agtgaggata acagcatcat
     2221 tgacattacc gcgggcctct ccggggatgt ggtgtcaatc gaattcaaga acactggaag
     2281 catcccaaaa gataagctag ctgccatatt tgaaaagttc tataggctgg acaatgctcg
     2341 ttcttccgat acgggtggcg cgggacttgg attggcgatt gcaaaagaaa ttattgttca
     2401 gcatggaggg cagatttacg cggaaagcaa tgataactat acgacgttta gggtagagct
     2461 tccagcgatg ccagacttgg ttgataaaag gaggtcctaa gagatgtata taattttggc
     2521 tctttgtcaa atgatgttgg taaagagaaa tct
//
LOCUS       DADQCX010000265         1520 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.211, whole genome shotgun sequence.
ACCESSION   DADQCX010000265 DADQCX010000000
VERSION     DADQCX010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.211"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            3..1403
                     /locus_tag="J8R83_002967"
                     /note="aph(2'')-Ia"
     CDS             3..1403
                     /locus_tag="J8R83_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HAZ9576026.1"
                     /translation="MDDDFPLMLKWLTDERVLEFYDGRDKKYTLESLKKHYTEPWEDE
                     VFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTR
                     YIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCY
                     LMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFST
                     NKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYST
                     MSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIE
                     KDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCD
                     FIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQE
                     FIENGRKEIYKRTYKD"
BASE COUNT          647 a          115 c          259 g          499 t
ORIGIN      
        1 taatagatga tgattttcct ttgatgttaa aatggttaac tgatgaaaga gtattagaat
       61 tttatgatgg tagagataaa aaatatacat tagaatcatt aaaaaaacat tatacagagc
      121 cttgggaaga tgaagttttt agagtaatta ttgaatataa caatgttcct attggatatg
      181 gacaaatata taaaatgtat gatgagttat atactgatta tcattatcca aaaactgatg
      241 agatagtcta tggtatggat caatttatag gagagccaaa ttattggagt aaaggaattg
      301 gtacaagata tattaaattg atttttgaat ttttgaaaaa agaaagaaat gctaatgcag
      361 ttattttaga ccctcataaa aataatccaa gagcaataag ggcataccaa aaatctggtt
      421 ttagaattat tgaagatttg ccagaacatg aattacacga gggcaaaaaa gaagattgtt
      481 atttaatgga atatagatat gatgataatg ccacaaatgt taaggcaatg aaatatttaa
      541 ttgagcatta ctttgataat ttcaaagtag atagtattga aataatcggt agtggttatg
      601 atagtgtggc atatttagtt aataatgaat acatttttaa aacaaaattt agtactaata
      661 agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt tttaaataca aatttagaaa
      721 ctaatgtaaa aattcctaat attgaatatt cgtatattag tgatgaatta tctatactag
      781 gttataaaga aattaaagga acttttttaa caccagaaat ttattctact atgtcagaag
      841 aagaacaaaa tttgttaaaa cgagatattg ccagtttttt aagacaaatg cacggtttag
      901 attatacaga tattagtgaa tgtactattg ataataaaca aaatgtatta gaagagtata
      961 tattgttgcg tgaaactatt tataatgatt taactgatat agaaaaagat tatatagaaa
     1021 gttttatgga aagactaaat gcaacaacag tttttgaggg taaaaagtgt ttatgccata
     1081 atgattttag ttgtaatcat ctattgttag atggcaataa tagattaact ggaataattg
     1141 attttggaga ttctggaatt atagatgaat attgtgattt tatatactta cttgaagata
     1201 gtgaagaaga aataggaaca aattttggag aagatatatt aagaatgtat ggaaatatag
     1261 atattgagaa agcaaaagaa tatcaagata tagttgaaga atattatcct attgaaacta
     1321 ttgtttatgg aattaaaaat attaaacagg aatttatcga aaatggtaga aaagaaattt
     1381 ataaaaggac ttataaagat tgattatata atatatgaaa agctattata aaagacatta
     1441 gtattaaata gtttaaaaaa atgaaaaata ataaaggaag tgagtcaagt ccagactcct
     1501 gtgtaaaatg ctatacaatg
//
LOCUS       DADQCX010000266          787 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.238, whole genome shotgun sequence.
ACCESSION   DADQCX010000266 DADQCX010000000
VERSION     DADQCX010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.238"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            33..770
                     /gene="erm(B)"
                     /locus_tag="J8R83_002968"
     CDS             33..770
                     /gene="erm(B)"
                     /locus_tag="J8R83_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAZ9576027.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          292 a          138 c          122 g          235 t
ORIGIN      
        1 tttatagatg taatcacttc aggagtgatt acatgaacaa aaatataaaa tattctcaaa
       61 actttttaac gagtgaaaaa gtactcaacc aaataataaa acaattgaat ttaaaagaaa
      121 ccgataccgt ttacgaaatt ggaacaggta aagggcattt aacgacgaaa ctggctaaaa
      181 taagtaaaca ggtaacgtct attgaattag acagtcatct attcaactta tcgtcagaaa
      241 aattaaaact gaacattcgt gtcactttaa ttcaccaaga tattctacag tttcaattcc
      301 ctaacaaaca gaggtataaa attgttggga atattcctta ccatttaagc acacaaatta
      361 ttaaaaaagt ggtttttgaa agccatgcgt ctgacatcta tctgattgtt gaagaaggat
      421 tctacaagcg taccttggat attcaccgaa cactagggtt gctcttgcac actcaagtct
      481 cgattcagca attgcttaag ctgccagcgg aatgctttca tcctaaacca aaagtaaaca
      541 gtgtcttaat aaaacttacc cgccatacca cagatgttcc agataaatat tggaagctat
      601 atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg tcaactgttt actaaaaatc
      661 agtttcatca agcaatgaaa cacgccaaag taaacaattt aagtaccgtt acttatgagc
      721 aagtattgtc tatttttaat agttatctat tatttaacgg gaggaaataa ttctatgagt
      781 cgctttt
//
LOCUS       DADQCX010000267          787 bp    DNA     linear   BCT 02-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V1288
            SAMN18323929-rid11859353.guided.239, whole genome shotgun sequence.
ACCESSION   DADQCX010000267 DADQCX010000000
VERSION     DADQCX010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18323929
            Sequence Read Archive: SRR13984702
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996782.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996782.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 03:10:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,969
            CDSs (total)                      :: 2,924
            Genes (coding)                    :: 2,854
            CDSs (with protein)               :: 2,854
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 34 of 70
            Pseudo Genes (incomplete)         :: 28 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18323929-rid11859353.guided.239"
                     /isolate="V1288"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2015-12-24"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            33..770
                     /gene="erm(B)"
                     /locus_tag="J8R83_002969"
     CDS             33..770
                     /gene="erm(B)"
                     /locus_tag="J8R83_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAZ9576028.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          290 a          137 c          124 g          236 t
ORIGIN      
        1 tttatagatg taatcacttc aggagtgatt acatgaacaa aaatataaaa tattctcaaa
       61 actttttaac gagtgaaaaa gtactcaacc aaataataaa acaattgaat ttaaaagaaa
      121 ccgataccgt ttacgaaatt ggaacaggta aagggcattt aacgacgaaa ctggctaaaa
      181 taagtaaaca ggtaacgtct attgaattag acagtcatct attcaactta tcgtcagaaa
      241 aattaaaact gaatattcgt gtcactttaa ttcaccaaga tattctacag tttcaattcc
      301 ctaacaaaca gaggtataaa attgttggga atattcctta ccatttaagc acacaaatta
      361 ttaaaaaagt ggtttttgaa agccgtgcgt ctgacatcta tctgattgtt gaagaaggat
      421 tctacaagcg taccttggat attcaccgaa cactagggtt gctcttgcac actcaagtct
      481 cgattcagca attgcttaag ctgccagcgg aatgctttca tcctaaacca aaagtaaaca
      541 gtgtcttaat aaaacttacc cgccatacca cagatgttcc agataaatat tggaagctat
      601 atacgtactt tgtttcaaaa tgggtcaatc gagaatatcg tcaactgttt actaaaaatc
      661 agtttcatca agcaatgaaa cacgccaaag taaacgattt aagtaccgtt acttatgagc
      721 aagtattgtc tatttttaat agttatctat tatttaacgg gaggaaataa ttctatgagt
      781 cgctttt
//
